LOCUS       DAFEEZ010000001       107624 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000001
VERSION     DAFEEZ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 107624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 107624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..107624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.001"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(98..1228)
                     /locus_tag="LP245_000001"
     CDS             complement(98..1228)
                     /locus_tag="LP245_000001"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBL1517954.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1288..1515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1877..3079)
                     /locus_tag="LP245_000002"
     CDS             complement(1877..3079)
                     /locus_tag="LP245_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1517955.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3139..3342)
                     /locus_tag="LP245_000003"
     CDS             complement(3139..3342)
                     /locus_tag="LP245_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBL1517956.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3484..4716)
                     /locus_tag="LP245_000004"
                     /pseudo
     CDS             complement(3484..4716)
                     /locus_tag="LP245_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4879..5691
                     /locus_tag="LP245_000005"
     CDS             4879..5691
                     /locus_tag="LP245_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1517957.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6715..6912)
                     /locus_tag="LP245_000006"
     CDS             complement(6715..6912)
                     /locus_tag="LP245_000006"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBL1517958.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7058..7936)
                     /locus_tag="LP245_000007"
     CDS             complement(7058..7936)
                     /locus_tag="LP245_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL1517959.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7975..9093)
                     /locus_tag="LP245_000008"
     CDS             complement(7975..9093)
                     /locus_tag="LP245_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBL1517960.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9090..11189)
                     /locus_tag="LP245_000009"
     CDS             complement(9090..11189)
                     /locus_tag="LP245_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBL1517961.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11240..12061)
                     /locus_tag="LP245_000010"
     CDS             complement(11240..12061)
                     /locus_tag="LP245_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL1517962.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12058..12867)
                     /locus_tag="LP245_000011"
     CDS             complement(12058..12867)
                     /locus_tag="LP245_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1517963.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12888..13382)
                     /locus_tag="LP245_000012"
     CDS             complement(12888..13382)
                     /locus_tag="LP245_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1517964.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13394..13882)
                     /locus_tag="LP245_000013"
     CDS             complement(13394..13882)
                     /locus_tag="LP245_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1517965.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13959..16655)
                     /locus_tag="LP245_000014"
     CDS             complement(13959..16655)
                     /locus_tag="LP245_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL1517966.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17083..18156)
                     /locus_tag="LP245_000015"
     CDS             complement(17083..18156)
                     /locus_tag="LP245_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1517967.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18153..18980)
                     /locus_tag="LP245_000016"
     CDS             complement(18153..18980)
                     /locus_tag="LP245_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1517968.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18981..19787)
                     /locus_tag="LP245_000017"
     CDS             complement(18981..19787)
                     /locus_tag="LP245_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1517969.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19799..20884)
                     /locus_tag="LP245_000018"
     CDS             complement(19799..20884)
                     /locus_tag="LP245_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1517970.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20901..21443)
                     /locus_tag="LP245_000019"
     CDS             complement(20901..21443)
                     /locus_tag="LP245_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1517971.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21701..22690
                     /locus_tag="LP245_000020"
     CDS             21701..22690
                     /locus_tag="LP245_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBL1517972.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22687..23424
                     /locus_tag="LP245_000021"
     CDS             22687..23424
                     /locus_tag="LP245_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBL1517973.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23421..23972
                     /gene="coaC"
                     /locus_tag="LP245_000022"
     CDS             23421..23972
                     /gene="coaC"
                     /locus_tag="LP245_000022"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBL1517974.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23988..24620
                     /locus_tag="LP245_000023"
     CDS             23988..24620
                     /locus_tag="LP245_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL1517975.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24705..25352
                     /locus_tag="LP245_000024"
     CDS             24705..25352
                     /locus_tag="LP245_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1517976.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25357..26340
                     /locus_tag="LP245_000025"
     CDS             25357..26340
                     /locus_tag="LP245_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBL1517977.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26743..28257)
                     /locus_tag="LP245_000026"
     CDS             complement(26743..28257)
                     /locus_tag="LP245_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBL1517978.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28395..29201
                     /locus_tag="LP245_000027"
     CDS             28395..29201
                     /locus_tag="LP245_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1517979.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29376..29945)
                     /locus_tag="LP245_000028"
     CDS             complement(29376..29945)
                     /locus_tag="LP245_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1517980.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30028..32088)
                     /locus_tag="LP245_000029"
     CDS             complement(30028..32088)
                     /locus_tag="LP245_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBL1517981.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32365..33843)
                     /locus_tag="LP245_000030"
     CDS             complement(32365..33843)
                     /locus_tag="LP245_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1517982.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34141..35076)
                     /gene="murB"
                     /locus_tag="LP245_000031"
     CDS             complement(34141..35076)
                     /gene="murB"
                     /locus_tag="LP245_000031"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBL1517983.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35149..36069)
                     /locus_tag="LP245_000032"
     CDS             complement(35149..36069)
                     /locus_tag="LP245_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1517984.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36182..36934
                     /gene="xth"
                     /locus_tag="LP245_000033"
     CDS             36182..36934
                     /gene="xth"
                     /locus_tag="LP245_000033"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBL1517985.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            37798..38331
                     /locus_tag="LP245_000034"
     CDS             37798..38331
                     /locus_tag="LP245_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBL1517986.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(38821..39345)
                     /locus_tag="LP245_000035"
     CDS             complement(38821..39345)
                     /locus_tag="LP245_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1517987.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(39338..39811)
                     /gene="tsaE"
                     /locus_tag="LP245_000036"
     CDS             complement(39338..39811)
                     /gene="tsaE"
                     /locus_tag="LP245_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBL1517988.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(39934..40914)
                     /gene="pta"
                     /locus_tag="LP245_000037"
     CDS             complement(39934..40914)
                     /gene="pta"
                     /locus_tag="LP245_000037"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBL1517989.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(41067..41747)
                     /locus_tag="LP245_000038"
     CDS             complement(41067..41747)
                     /locus_tag="LP245_000038"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBL1517990.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            41873..42742
                     /locus_tag="LP245_000039"
     CDS             41873..42742
                     /locus_tag="LP245_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1517991.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            42768..43283
                     /locus_tag="LP245_000040"
     CDS             42768..43283
                     /locus_tag="LP245_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1517992.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(43330..43923)
                     /locus_tag="LP245_000041"
     CDS             complement(43330..43923)
                     /locus_tag="LP245_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1517993.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(43948..44127)
                     /locus_tag="LP245_000042"
     CDS             complement(43948..44127)
                     /locus_tag="LP245_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1517994.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(44204..44713)
                     /locus_tag="LP245_000043"
     CDS             complement(44204..44713)
                     /locus_tag="LP245_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1517995.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(44809..45189)
                     /locus_tag="LP245_000044"
     CDS             complement(44809..45189)
                     /locus_tag="LP245_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1517996.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            45518..46267
                     /locus_tag="LP245_000045"
     CDS             45518..46267
                     /locus_tag="LP245_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBL1517997.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(46451..47728)
                     /locus_tag="LP245_000046"
     CDS             complement(46451..47728)
                     /locus_tag="LP245_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1517998.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(47807..48451)
                     /gene="pcp"
                     /locus_tag="LP245_000047"
     CDS             complement(47807..48451)
                     /gene="pcp"
                     /locus_tag="LP245_000047"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBL1517999.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(48650..49594)
                     /locus_tag="LP245_000048"
     CDS             complement(48650..49594)
                     /locus_tag="LP245_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBL1518000.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(49596..50282)
                     /locus_tag="LP245_000049"
     CDS             complement(49596..50282)
                     /locus_tag="LP245_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBL1518001.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            50756..51076
                     /locus_tag="LP245_000050"
     CDS             50756..51076
                     /locus_tag="LP245_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBL1518002.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            51230..52135
                     /locus_tag="LP245_000051"
     CDS             51230..52135
                     /locus_tag="LP245_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1518003.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            52132..52905
                     /locus_tag="LP245_000052"
     CDS             52132..52905
                     /locus_tag="LP245_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL1518004.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(53086..54510)
                     /locus_tag="LP245_000053"
     CDS             complement(53086..54510)
                     /locus_tag="LP245_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1518005.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            54721..55167
                     /gene="nrdI"
                     /locus_tag="LP245_000054"
     CDS             54721..55167
                     /gene="nrdI"
                     /locus_tag="LP245_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBL1518006.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(55232..57214)
                     /locus_tag="LP245_000055"
     CDS             complement(55232..57214)
                     /locus_tag="LP245_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1518007.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(57228..58124)
                     /gene="murQ"
                     /locus_tag="LP245_000056"
     CDS             complement(57228..58124)
                     /gene="murQ"
                     /locus_tag="LP245_000056"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBL1518008.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(58127..59188)
                     /locus_tag="LP245_000057"
     CDS             complement(58127..59188)
                     /locus_tag="LP245_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL1518009.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(59399..59965)
                     /locus_tag="LP245_000058"
     CDS             complement(59399..59965)
                     /locus_tag="LP245_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL1518010.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(59993..61495)
                     /gene="eat(A)"
                     /locus_tag="LP245_000059"
     CDS             complement(59993..61495)
                     /gene="eat(A)"
                     /locus_tag="LP245_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBL1518011.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(61753..62874)
                     /locus_tag="LP245_000060"
     CDS             complement(61753..62874)
                     /locus_tag="LP245_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL1518012.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            63000..63941
                     /locus_tag="LP245_000061"
     CDS             63000..63941
                     /locus_tag="LP245_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL1518013.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(64091..64987)
                     /locus_tag="LP245_000062"
     CDS             complement(64091..64987)
                     /locus_tag="LP245_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBL1518014.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            65256..66596
                     /locus_tag="LP245_000063"
     CDS             65256..66596
                     /locus_tag="LP245_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1518015.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            66814..67257
                     /locus_tag="LP245_000064"
     CDS             66814..67257
                     /locus_tag="LP245_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBL1518016.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(67761..69179)
                     /gene="nhaC"
                     /locus_tag="LP245_000065"
     CDS             complement(67761..69179)
                     /gene="nhaC"
                     /locus_tag="LP245_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBL1518017.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(69582..70805)
                     /locus_tag="LP245_000066"
     CDS             complement(69582..70805)
                     /locus_tag="LP245_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBL1518018.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(70836..71675)
                     /locus_tag="LP245_000067"
     CDS             complement(70836..71675)
                     /locus_tag="LP245_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL1518019.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(71692..72372)
                     /locus_tag="LP245_000068"
     CDS             complement(71692..72372)
                     /locus_tag="LP245_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518020.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(72374..73447)
                     /locus_tag="LP245_000069"
     CDS             complement(72374..73447)
                     /locus_tag="LP245_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1518021.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(73503..73741)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(73784..74017)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(74094..74765)
                     /locus_tag="LP245_000070"
     CDS             complement(74094..74765)
                     /locus_tag="LP245_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL1518022.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(74852..77530)
                     /gene="mgtA"
                     /locus_tag="LP245_000071"
     CDS             complement(74852..77530)
                     /gene="mgtA"
                     /locus_tag="LP245_000071"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBL1518023.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            78189..78626
                     /gene="ndk"
                     /locus_tag="LP245_000072"
     CDS             78189..78626
                     /gene="ndk"
                     /locus_tag="LP245_000072"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBL1518024.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(78648..79514)
                     /locus_tag="LP245_000073"
     CDS             complement(78648..79514)
                     /locus_tag="LP245_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL1518025.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(79674..81767)
                     /locus_tag="LP245_000074"
     CDS             complement(79674..81767)
                     /locus_tag="LP245_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL1518026.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(82516..83139)
                     /locus_tag="LP245_000075"
     CDS             complement(82516..83139)
                     /locus_tag="LP245_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518027.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(83298..84695)
                     /locus_tag="LP245_000076"
     CDS             complement(83298..84695)
                     /locus_tag="LP245_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1518028.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(84727..85698)
                     /locus_tag="LP245_000077"
     CDS             complement(84727..85698)
                     /locus_tag="LP245_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1518029.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            86072..86497
                     /locus_tag="LP245_000078"
     CDS             86072..86497
                     /locus_tag="LP245_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518030.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(86985..87686)
                     /locus_tag="LP245_000079"
     CDS             complement(86985..87686)
                     /locus_tag="LP245_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL1518031.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(87702..88142)
                     /locus_tag="LP245_000080"
     CDS             complement(87702..88142)
                     /locus_tag="LP245_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBL1518032.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(88142..88717)
                     /locus_tag="LP245_000081"
     CDS             complement(88142..88717)
                     /locus_tag="LP245_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBL1518033.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(89565..90044)
                     /locus_tag="LP245_000082"
                     /pseudo
     CDS             complement(89565..90044)
                     /locus_tag="LP245_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(90203..90904)
                     /locus_tag="LP245_000083"
     CDS             complement(90203..90904)
                     /locus_tag="LP245_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1518034.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(91012..92421)
                     /locus_tag="LP245_000084"
     CDS             complement(91012..92421)
                     /locus_tag="LP245_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBL1518035.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(92469..94334)
                     /locus_tag="LP245_000085"
     CDS             complement(92469..94334)
                     /locus_tag="LP245_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1518036.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(94455..95306)
                     /locus_tag="LP245_000086"
     CDS             complement(94455..95306)
                     /locus_tag="LP245_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1518037.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(95616..96329)
                     /locus_tag="LP245_000087"
     CDS             complement(95616..96329)
                     /locus_tag="LP245_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBL1518038.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(96397..96723)
                     /locus_tag="LP245_000088"
     CDS             complement(96397..96723)
                     /locus_tag="LP245_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBL1518039.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELVDVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(96846..97073)
                     /locus_tag="LP245_000089"
     CDS             complement(96846..97073)
                     /locus_tag="LP245_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL1518040.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(97395..98366)
                     /locus_tag="LP245_000090"
     CDS             complement(97395..98366)
                     /locus_tag="LP245_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL1518041.1"
                     /translation="MMDYLGKRHLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTY
                     PTEHYFGGICILLSWGVIYLVLGSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQV
                     KERQHQESLQLYQINEEYYHHLEEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHS
                     AAIFEKPQIQQLTNIVSPAVRGVFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIR
                     CLSIFISNAFDHRVADQSPITINLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKK
                     NGGLGLYSAKKMLDVYENAELKIEFSKQNHYFFVEMYLASRKSKSAY"
     gene            complement(98413..98649)
                     /locus_tag="LP245_000091"
     CDS             complement(98413..98649)
                     /locus_tag="LP245_000091"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518042.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFLFYYEKPVYQLFDQ"
     gene            98710..99450
                     /locus_tag="LP245_000092"
     CDS             98710..99450
                     /locus_tag="LP245_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1518043.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(99536..100294)
                     /locus_tag="LP245_000093"
     CDS             complement(99536..100294)
                     /locus_tag="LP245_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL1518044.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(100291..101319)
                     /locus_tag="LP245_000094"
                     /pseudo
     CDS             complement(100291..101319)
                     /locus_tag="LP245_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(101339..104506)
                     /locus_tag="LP245_000095"
     CDS             complement(101339..104506)
                     /locus_tag="LP245_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518045.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(104730..105614)
                     /locus_tag="LP245_000096"
     CDS             complement(104730..105614)
                     /locus_tag="LP245_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBL1518046.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(105709..106146)
                     /locus_tag="LP245_000097"
     CDS             complement(105709..106146)
                     /locus_tag="LP245_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518047.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(106363..107274)
                     /locus_tag="LP245_000098"
     CDS             complement(106363..107274)
                     /locus_tag="LP245_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL1518048.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
BASE COUNT        31369 a        22456 c        18437 g        35362 t
ORIGIN      
        1 aataaataat ataaaaggta aataaaaaag agtggatttc tccactccat gaaaagccga
       61 ctttttggga cgcttttttt tgccaagcct cacattttta tagccaaact tcttttgcga
      121 cttgctgcaa taattggatt ttcttccatt gttcttcttc tgttaaatgg tttccttctt
      181 ctgttgaagc aaacccacat tgaggactga tacttagatt ttccaatggt acaaattgtt
      241 gtgcttcttt tattcgttct tttattttct ccgtatcttc caaatctgga aacttagaag
      301 taactaatcc taaaacaact ttactttctt tgttactcca atgtcttaaa ggagtaaaat
      361 ctcctgctcg gtcagaatcg tattccaaaa agaaaccatc ataatttgtt gaaaacaact
      421 cttctgcaat gggttcatat ccaccggaaa acagccaaga agaagcgtga ttcccgcggc
      481 agatatgtgt tgtgatcgtc aaatcttctg gtttgtcttc cagtgcgtta ttgataatct
      541 ctgtacaaat atgggccatt tctttcggat caattccttt ttgaagaagt gcttctcttt
      601 tagtttgatc agctagaaac gcccaatttg tatcatcgaa ttgcaggtaa cggcaacctt
      661 tttcataaaa agcatgaatc gctgctttgt aagtagagga caagtcctca taaaaatcag
      721 atagatcagg ataaatctcc ttgatttttg aagaaccatc attagatagg atctcttgtc
      781 gtaaaatcat cgtgggacta gggatcgttg cttttgcaac aaaagtatca tctgtttcca
      841 ctacttcttt cagaaaagca aaatctttta aaaatgggtg atttggattg aaagataatt
      901 tatctactac ccgaatatta taagctggtg ctgcttttcc gtggaatgtt tgattatatc
      961 cagtttctgg aacatagcct tcgataccat ttagttcttc taaaaaatca agatgccaaa
     1021 atccacgccg aaattcacca tctgtaattc ctttgatgcc gactgctttt tggtcttcca
     1081 ctaatttttt tatttcctgg tcttcgattg cacgaagttc ttcttttgaa agtaagcctt
     1141 cttgaacttt ttttcttgct tctttgatcg attgcgggcg taagaaactt ccgacatgat
     1201 ctactgtaaa tggtctattt ttgctcattt cactcactct tttctttgtt ttttgtaaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga accatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagatgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattttgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatcgac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta gaaccggggg ctttattcct gcagtccggc
     5821 tacgccttcc tgcaatagac aaaactccag atcgggtaat tcgcttgtgg cgaaacccga
     5881 cctggagttt gtctctgtat tttgaaccct aaaaattaat caaacagact gatattctca
     5941 taatcagcgc gaaataagcc attaagtaca gttttcctac ctatttttga taacccgctg
     6001 gttagttaat attccttttc cgagagagat aaatgattgg ttaaatctat atacatctca
     6061 acctttaaaa atgttttcga aatacttcat cagtacatgt catacaaatt accagtgcat
     6121 tctcaaattc tagttcttta attgatttca gttgaggagc agttactttt ggcggaaatt
     6181 tccatttttg tccaaacctc ttcccccgat gaaatttctt tgttgcaatt attgcaatga
     6241 aaaatttttg tttcaaaaat atacataatt acttcctcca ataaaaacta tctacctctc
     6301 aaattatttt tctctaataa gaaaaacaga aaaggtaata agatacaaca gtgatgattc
     6361 ctaataaaga aaagactaca ataatatttt tctaacttat cgccttcaaa gaaatagttt
     6421 cttatttttc actaaaataa aaaatttatt gcaaaaaaaa tagaagtgac aaaattatca
     6481 atcatttcaa ggtaatataa ctacctgagt ttattatcga ttaaaatgct aactacattt
     6541 gcaagagaag cgagagttaa aggtaaatat agaatttcta cttttttagc aatagaaata
     6601 ggaataaaat atttaaaatg tatagaaact ttcttttttt ttcttgctat ctttttataa
     6661 tcacaactct ctataataga attacgattt attttatacg gctgaaaaaa tctatcacca
     6721 aaaaaattca aacattaagc caaggattat gaagtcaaca tttcgaaaaa tgaacataca
     6781 ttggtaagca actataacta ttaccacaga cataaagtaa cacaatatat tactatttaa
     6841 gtgtacgcca ccagtgaata tcctcaaggt atacagcgca caacaaaaag aaaaaaggaa
     6901 acgcagaagc atttcctttc agtgatttaa tgaaaacaac acgatttgac ttagagcctt
     6961 tttatttgaa ttcattttcg ctttatccaa cttcatttga tcatttgatt actcggttaa
     7021 atacttttga catgagtatc aatgaaacat tcattaatta tggttgctta tttcttaccg
     7081 cttttctggc caatgctaat ccgccgatta ttccggcatt atcacctaat tcgggcgtaa
     7141 taatgtagct atcaattggt ggtatttcaa catatccatt tataagctca acaaatttat
     7201 cctgaacttt tttcttcatg tgttcttgtt tcattacacc accgccaaaa ataattctat
     7261 ctggcgaaaa catcagtgtt gtattgtatg cacattgggc aaggtaaaag gcttcaatct
     7321 gccaaaacga atcgtcagcc aataaattct ggccttttac acccaaccgt ttttcaatcg
     7381 ctggtcctgc tgccatcccc tctaaacaat cttggtggaa gggacagttt cctgaaaaat
     7441 tgtcctttgg atgtcgcttg atcaacatat gccccatttc cggatgactg aacccttcca
     7501 cgaaagtccc attgaacaag gcaccacctc cgatacctgt tcccacagtg aagtatgcaa
     7561 cacctgctaa ccctttgcca gaaccagcaa catattcacc atagcaagcc gcattgacat
     7621 ctgttgtcca ttcaatcgga atattgaaat attgctttag cgttcctaca aaattgaaat
     7681 tttgccaagc aagttttggt gttgatgtga tatgaccgaa actcgttgat ttgcattgaa
     7741 tatcaattgg accaaagcag ccgaccccga tgcctgccaa ttgttcctta aaaggtttaa
     7801 aaaaatcaat gacctgcttc attgtttcaa ctggagttgt tgtgggaaaa ctgactcttt
     7861 ccaaaatcgt taattcctca gtaccgactg cacagacaaa tttagtccct ccagcttcaa
     7921 ttgccccata tatcatcata ggttcctccc ttcgaatatg tgaaaaacac ttcattaacg
     7981 cggcaagcgt tctcgatcag tgaaatgacg tttagtattt cctgaagctt ctgttgaata
     8041 ccagtaagcg acactagcaa catcgtcttg ccgctcaaat aagcgaacat catcgttgcc
     8101 gatttgttgt aaagtgaccg ataaatcttc ggtaaaacag atggggtctt gaagatgcca
     8161 acgataaaga ccatgtcgtg gcattgcgtc gtcaccaaag gcatgaacgg cattcaattt
     8221 tcccgtttca aaacgatctc ttgtggcatc tctatttgat tggtaaggat accctaaaaa
     8281 ggctgttgaa tagtttttcg catgtggacg tccgaactca tcgtactcat gaaaggccca
     8341 cgccccgcca aaataatctt ctgaacctgt tgaggttacg gtcggatact cactatcccc
     8401 atcaatgtag aatttaaact cgccttcgcc ccaccaataa cgttctaggc aggtaagcgc
     8461 aaggtaagta cccacgtaat agccttgacc ctttaatcga tcaattaact tataatcctc
     8521 ctgtaatttg gtaatgcgtt cccgatgcca atttgcgtga aaatataggc tattttcttc
     8581 caattcgtcc accaaagcgt aatttatcgt ataaaaaaat gaggacatat ccttcggatg
     8641 taaattctcg atcgtaattt tagcggatgt ttggaaaggc atttcgaaat aggaattaaa
     8701 gccccctgta ggattaacca ctatcggcaa cgagttcacc tcgcaacgct ctccaaaccc
     8761 attacaaaag aaatccccta aaggactttc aacagcaggg ctatccgacc catcccaata
     8821 aattcttaag attaaatcac gtaaaacaaa actgccaaat tctgttcgat cacgaatcgt
     8881 catccacata tgacgaatta ttcccgttcc agtaatatcc gcaatcacag tttcttcacc
     8941 agaagtcagc ggaattgcgc cacgaccttt gcggcttggt cctagctcgc ttggcaacat
     9001 cgcagcttta cctttctcgc ctgttggatt ttcgggagtg attgctcgac tctggatttt
     9061 tttaaattgg gtaatatttt ttagtatact catctttttc tcctttgaat gtgaatcgtt
     9121 tttccctttt ctacgtgaag aatttttttc gtatcactta ttttcaatgg cttttctgac
     9181 aaatttgaaa tactcaactc ggattgcgta cattcaatcg aaatgaaggc ttgaccgaac
     9241 ttcaaattct tccaagaaaa cgttaaatta tcaacaggat caatttgcaa tactcctttt
     9301 ttgaatttca atccgaaata ttgactgatc attaggctga caaaaagacc cgatgcccag
     9361 ccgcatttgc cgcagccaaa gtctcgcacg acttctcctt gttgagcctc taagcgatac
     9421 ggccaccacc accacgaacc gtctaaatct gccaaacaaa ttagttcttc taatcgggtt
     9481 acgaaagctt gagggttgtg cagctcgctc attaaaacag tgataaagcc aggaaaagtg
     9541 gcgccggatt ctaatcccca agtgatgcct ttgatttcct cgctataggt tggattgaaa
     9601 gaactagcag aaaaggccat ggtgttctga tataaatgat ctttattatc taaaaattga
     9661 taaaaaggca tcaacgtagt gtctgattct tctccatcat gcatcaataa attaattttt
     9721 ccatccacaa tcacatcact taaaaagatt aacccttgct caagaatcgg tttttgatag
     9781 tgcttcactg aataggttgt tttctcctca tcaccgattc cctccaaaaa ttgctcacca
     9841 aaaggaccat cgatagtcat ttgtttacaa attgattcct ttagtttaca ggcaatgttt
     9901 ttgtatcgct tgctaagact cagttgttct agggcttcaa aaatttctgc aagtccaata
     9961 caggccttcc aaagacaaag attgctgccg gtatgatact ttccaagtgc aaaggcgtct
    10021 gataaccaaa cagatggaaa aagcattggt tcccctgacc gacgttgagc taatatgtcc
    10081 tcaataattc ttgaagcatt cagtagaacc tgcggacacc gctcaaagaa ttttgtatcc
    10141 ccagtatgtt caaaataaag actagccagt aacgcactgg ataacgaatt actcagagaa
    10201 tgattgatac ctcctgtaaa ttttgaacca ggaaacttaa cgccatattg atcaaaccat
    10261 agaaccgttt tttgacataa ctccggttca aacatggtga atggcaatga tgcgtaatac
    10321 atatccttat tccaaattcg attagtagca ggatagctgc cccaattgct gccgacgacc
    10381 tgtccctgtc gattcatacc gaaactagaa aagctttgat aaagtgcacg acgatagaga
    10441 tggacaactc tatcgtttgg cattgacagc tgcccaaata gctgagcaaa atagttcaat
    10501 gtttccttca gccatttttc gatatcagat tcctgaaaag tcattacttc ttcaaaagca
    10561 tttgggtcca caaaagcaat ggcgaagctt gccacttcct gttgtgcgat cgtgtcctta
    10621 tttccttttt gagaaatcaa cacattttgc tgatccgaat acttctcttg atacgaaggc
    10681 acatctttca ctgaaacttg aaggctttcg tgtgtttcat tcacaatgta aacctgttga
    10741 acaagcatac ttaaacgctt attagccagt atgggagcaa aggatactac aatgacctta
    10801 aacgtcgaat aatgatgaat atatctaggc aaacagtctt gaatcacatc gacttcaata
    10861 cgatgatccg attctgacaa atggtagaca atcccgttta cttcaacctt taaggataac
    10921 gaattggttt gagagagctg tttattgacc caaacacctg gtttttcctc agttagtaaa
    10981 ttttctcgat aaaaggtcaa cgtttgaatc gtcccgcaaa catcaaggtt tgctaatgtc
    11041 ttttgattac ttacatcgaa ggtcaatccc tttacatcag gaatattccg atagtagctg
    11101 tattcgtttg aagtagtcac atttccgtcg tttaactcag cattaaaaaa tgggtgtttg
    11161 ggtgaataaa ttacttcatt aatagtcatc ttttccctcc ttgctaaaaa aactgcagcc
    11221 tagtagctgc agcttcctac tatgcgattc caagtaatga caataaaatt cccaagacga
    11281 ccattccaaa aataattttg atgacgccga cttttttatc tagtaatttg aaacagctca
    11341 atgttaccaa taacggtaca attcctttaa aaatactatc gaggatttct tggacattca
    11401 ttagttcttc gcccttcatt gaaaagctca aaacggtatt gaatttgacc atactgatcg
    11461 tcattgcacc taccatgatc agacccaaga tactagcagc ttttgtcaga atttcaatta
    11521 acccgttcgc atacagcttt tcaatatatt tagagcctaa tgaatagcct aaaacgccgc
    11581 catagtatcg catcaagtaa ttaggtatat tgaacataac taaaaagata attggtgcca
    11641 aaatatttcc ggcattggct aagttgatcg ctagtcccgc ggtaacgaca cgccaaactc
    11701 cccagaacaa tgaatcgcca attccagcca atggtcccat caaactcgtt ttgatcgcgt
    11761 tgatactttc cacgtcaaaa ccagcttttt cagaattttc cttctccatc gatgccgcaa
    11821 tccccatgac aaaggacgcg caaggaatgg tcgtcgaaaa atactgtgta tgacgttcca
    11881 gcgccgcagc tcgatcttct tcacttttgt agaaatgatt aatgaagggc atcatagaat
    11941 aggcgaaacc accgccgccc atcgtcaccg gattcaccga agcatacata gtcatcgagc
    12001 gccaaaacat cttccgaacc aattttttct catctttaga aattccatca gctaatttca
    12061 ttgaaagaaa tcctcctctt cttggtcaag cgttgcattt acagcagcat cgctttgaac
    12121 tgcatgaaca gatatatttt ttagttgtag atctctttgg gctataacaa ttgcaataat
    12181 cgttccaact gcggcaattg caatcaatgg taactcgaga tacgccataa caacggcccc
    12241 aaagaaaaac cacacagcaa tatttttact ccaaagcatc cgtaacagca tcgccatccc
    12301 aactgccggc agcagatttc cagcgactgt taatccgttc atgatgacct ctggaatatt
    12361 atccaagacg cttttgacaa catctgctcc aaataaaacg gcaaagaatg gaataagagc
    12421 ataaagcgca tagtggacaa accacataaa gaagtgcaga ttgatgattc ctttttgatc
    12481 accagatttt gcaaatttga aaaatttagc agccatcggt ccacatacaa aagaaaaaat
    12541 catattcatt aactgtaatc ctaatactgc tagtggaaag acaatgggaa taatcgcatc
    12601 cacgtttcct cccattttga ttgcgaacgc tgtagccagc ccagcagcca aagaaggctc
    12661 cgccgtacta gagattccga tattgacgac acccataaag atggcttcta gtgacgcccc
    12721 gacaatcaac cccgtctgca aatcccccat caacgctcct gctaacggag caacaacaat
    12781 cggacgactc agcatggaca tcccgaacat ttcatgtcca gcaactccaa taaaaacggc
    12841 caaagcgact acaaatgcat catacataat ttttctcctt cctttttcta aaaatcactc
    12901 aaaatagaga tagctgaacg tttttccatc gccggtgtag gctgaaaaac ggtatctgga
    12961 taaagttcaa ctaattcttt taagtcttga atttctgacg tcgttaacat cacttccttt
    13021 gataaggttt tcttatcttc cgatggcggt gtcattttcc cagcattccc cacgttcatt
    13081 aattcgattt ccgttgggaa agctttcgca acttttaccg catctttgac attagggact
    13141 aaaaccatca agcgcatgtc cttcgcccgc ggatctttta acaaatgaat cgcgtcatca
    13201 actgttttaa taatgacttt gacattcgat ggtgcagcca tcttcaatgt catcttttga
    13261 atatcgttgg tagccgcctc atcgcttgct actactaacc cggttaaatt tagactcttt
    13321 gtccaagtca tcgctacttg tccatgaatt aatcgttcat caattcgcac tgctttaatc
    13381 atttttcttc ctcctaaaaa aaatcttcct cttcatttac tacatgtacc tcatcaagaa
    13441 tggtcatctt taattcctgt tggcatttat ttaccagttc ctgaatatcc tcctttgtta
    13501 attccttggt tgccaatact atttcgagca gaattggcag attaaagcca gacaaaatag
    13561 ttacagcaat ctctttctcc aaaaaggttt tggtaatctt ctgattgaca cttccgccaa
    13621 ataaatcggt aaaaacaaaa atctgatcct gctcgttcac ctggtttaca aatacattca
    13681 actcctgttc aaaatcacac tcatccacat aagcattaat caccgtaatc tcttgaacct
    13741 tccccgtcag taattgaata ctgctaagaa agcctgaagc taagtgaccg tgagtcgcta
    13801 ttagaatttt cttcatatgg ttaattcctt tctttctgtt cacttttata taagcaattc
    13861 ctgtgccaac ttttaaaaac attggtttaa tcacgttaat tcacattaaa aaaagtgtct
    13921 aacctaaaaa aaacagatta gacacttttt tagacacttt atttttgaat atacggtcct
    13981 aataattcat agagcagcga aagctcataa gcattgactt taaaattata tttcatctcc
    14041 attgattgaa aaatacttct agaaacataa taaaattcat cttcatctgg tttcaaatca
    14101 taattcggtt cttcagattt ttctgtccga gccaagaata aacgttccat catcaatgcc
    14161 gtatgcatat agagatttag ttttacacgg ccatttaaag tgaaatgata gtaattttca
    14221 tatttagaaa tgactgtttc cacttcactc atcacgatcg ttgggttcag aaagttcaaa
    14281 cggtccgcaa ttccttccaa cgaaaagaat tttactagct cctgaatcaa gcggttaaat
    14341 tctgccggct tcatttcagg actcaaaata tgctccaaat tggctgctcc atcaccgtct
    14401 aagatgtcat aaacattaat attaggaatt gaaaaggaac gtggaagatc cgaagtcgtg
    14461 atgaccaatt ttgtcttgtc aaaataagtt tcatcatttt ggtcgattaa ttcacgtagt
    14521 tctctgtagt ccttcgtgaa aacttcgatg gattcatccg ataaatgatg acgaaaaaca
    14581 tctttcaatt tgtccgaaat ccccaaaccc gacatacagg aaatgataat gttgctactt
    14641 tgagaaaagc cttcaaagta ttgaacattg attgaatact tgtctgctgc atcctccgca
    14701 atctgtttaa atggcgcatt catcgtcatc ttcaagccaa tatcaagtgc aatggaagtc
    14761 gtcaaattat tcagaagaag taactcccct tttaaatcgt tcttgatctg tgtgtaaatt
    14821 tgatttaaag agcccatatc tacgatcagc actagactat ctgtattcac ttgccgtttc
    14881 acgaaattcc ttgtcgattc gacaatctct gacacattac tctctactgg catatccaac
    14941 gcttcaaaaa cataattgcc gcataattga ttcactactg cttgaatgct gctagccgta
    15001 ctatctccgt gagcaagcaa caggcccttc agctcgatgg attcatctac ataatcagat
    15061 aaagtcacga caataagcag tcttagaaag ttctcgtcct tttctgagag cggtggtaaa
    15121 tgctccaaga actgattaca taagtaagtc gtccgaggta gatttgcagc taatgtacga
    15181 tttatcccgg ttaagtctgt cttatagctt ggggaaatga cataggatct gctaataatt
    15241 tctgcaacag gtccactcgt cgtcaatccg tacgtttttc ctaaaacgga tacccagacc
    15301 tttctaaaca tctgaatcat caattttcta ctcattgata aaaaagaatc cttatcaatg
    15361 tgatgcacca aatgctgtac ttcattcttt atcgaagaaa aattttcatt gaaattacct
    15421 tcatttatca gctgagtaat tttttccaaa atcgaatcat aatcaaacgg tttgattcga
    15481 tccgttttta tcttttgatt tttctttatc aataaactag caatcggcaa gctttctact
    15541 tcggattcca gcatatttaa ctgaatcaag atctcatttt tcccaatcgt taatggttct
    15601 tcttgtgttc gactatacac atccgcacaa ctgattttaa tgatattctt cagcttacca
    15661 atattcccac taaagggatg agataacatt aaagacaagg cttctcttga aacaataata
    15721 tctttttgta aaacatccgc ttcattttga aaaaataatt gaatcagctc taatcgttct
    15781 cgaatggggc gatcttcaaa agttggcaac ataacactaa tttgaatacg ccgatcaaag
    15841 gtgtctaata aataattttc acctttttcc gtcgtggcga aaataaaacg aaccttagca
    15901 gaatgccaat ttacattttc accgactgga cgatagtttc cagtatcaat aaatagaaag
    15961 agcttttctt gattttcttt cgataggcga tggacctcat cgagaaaaag atagccgttg
    16021 ttggccgttg ccaataaacc atcggtatcc ttttcagccc ccgtaaaggc ccccttcttg
    16081 tatccaaaca gtgttgccga aagcagttcg ggattgtccg cataatcggc acagtttaag
    16141 atagcaaatg gtgcatcttt ttcaataatt tgctcatgga tagcgtattc aaaaattttt
    16201 gtggctaaaa aactttttcc aacacccgtg gctccattta ttaatacact gagtccgtta
    16261 ggcggatatt tgacagcggc tatacatttt tgaatgacct ctctcagact tccgtcatga
    16321 ccaactacag aatgaaaggc ttcgtttatt tgctccgtat tatctacaac cgcatattca
    16381 tctaaaggct tccacaaaac aggctttccc ggtaatttct cgaccttttt atcttccact
    16441 aatctcgtca aataatggct ggcattctga cgagagatac ctagattctt cgaaattttc
    16501 tcggcagtga cagaagacat attccctgtt agtcgtatca gctcatcaaa aactcgatct
    16561 ttagcgctct ttttcatttt ttcctccagt ttaatgtgtc taaaagcata ataaactatc
    16621 ggctgcaata tgtctattct atatttgtat tccaattttt actttgaaac acaaatagtc
    16681 gaatatttgc ctcagatatc tgacaaaata atttatctac caatttagtt tttatctaat
    16741 atgattttta tgttttttca tagctacaaa tattgaactg gattcatata ttagttttat
    16801 taatagatta cagaagggtt aagtatattt gcatagtttc caattacttt atccttctgt
    16861 aactttttca atcttagatt tactagcccg tctcgggccc tattttacaa tggttttgtc
    16921 cacttttctc tggtagaaaa acgtggtaga aaaaataaaa taacacaaaa aaagcggcgt
    16981 ttcatccgct tttggtagaa gattggaaaa ctcagataga aaaaggacga tttttagctc
    17041 tttagaacgt tgataagtcc ccattcttac tgagttttgc cattatctcc tatacatctt
    17101 gaattctaag aataggtcat tatagatgcc taggtatttc gatcctagat ctttgtagac
    17161 ttcaagatgg gagatcgtgt catcagatgg atagaattgt tcgtccgacg aaatgtcttt
    17221 tggcaataac gcttttgctt cttcatttgg tgtagaataa ccaatatact ctgcattttg
    17281 tgccgcattt tccggttcta gcataaagtt gatgaaatca taggcacctt ctttattttt
    17341 cacggttttt ggcataacga tattatcaaa ccaaagattg gatccttctg gtgggatcac
    17401 ataatgtaaa tgttcatttt cccacatcat atcggcagct tcgccagaaa atgtcactgc
    17461 cacggaggct tcttcattga tcatatacat tttgatctca tctgccacga ttgctttgac
    17521 atttggtgtt aaatgattca atttatttgc tgcttctgtc agctgtgcca tattcttact
    17581 attcaaagaa tagcctaaac tattcaaaga aagccccata acttctcgtg caccgtcaat
    17641 cagcatcaaa ctgtctttta attccggctt ccacaaatca tcccaatgct taatttgatt
    17701 tgcatcaaag aatttatcgt tatatacgat ccctaaagtt ccccaaaaat atggaatcga
    17761 atactgatta tctggatcaa aatccaagtc taaaaatcgt ggatcaatat tatttaatcc
    17821 tttgatcttc gaatgatcta atggaagtac tagtttttct ttgatcattt tttggatcat
    17881 atattcactt ggtatagcga tgtcgtagtt tgtcccacct tgctggattt ttgtgaacat
    17941 cgcttcatta gaatcaaatg tttcataatt cactttgtat ccatattctt tttcaaattt
    18001 cgtgatcaaa ctaggatcga tataatctcc ccagttatag atggtaagta cctttgctcc
    18061 actcatgcca cttgtttttt caagttgacg aacaccaagc agcagcaccg caataatgat
    18121 gagaatacct aaaaacagag attgtaattt tttcatcgca gccgtgccac cccctcgcgt
    18181 actcttctgt ttttcttcag ccgttttgga cggttttctt tactaataaa gtagtatcca
    18241 atgaccaata tcatggagaa caagaaaact aacgcactta gcgcattgat ttctaaactg
    18301 attccttgtc ttgcacgaga atagatctct actgagagcg tcgtaaagcc atttcctgtg
    18361 acgaaaaatg taaccgcaaa atcatcaaga gaataggtaa atgccataaa atatccagct
    18421 atgattcctg gagaaagata aggcaaaatg atatttttga ctacttggaa attattagca
    18481 ccaaggtctc tagccgcatc gaccattgaa tcgttcattt cctgcaattt tggcaagacc
    18541 atcaagacga cgattggaat gctgaaagca atatgggaaa gcaatacact ctgaaaacct
    18601 aatccgaatc ctagtagtgt aaagaaaatc aagaaactag caccgataat aacatcagga
    18661 gagactaata agatgttatt catgctcaac aacgctgtcc gtgcacgtcg ttttttcgtg
    18721 taatagattc ccatagcccc aaatgtcccg atgatcgtgg cgatcaatgc agataagaaa
    18781 gccagcatga acgtattcaa tacgataatg atcaaacgtg tatcttcaaa aacagcttca
    18841 taattttccc aagtaaatcc tgtaaagctg ttcatcgttc ctccttcatt gaaggaataa
    18901 aaaatcagat agaagatcgg tgcatataag aataaaaaga cgatccctaa ataaagatac
    18961 gaccatttaa attttttcat ttatgagcga cctccttttt tcttctcgcc tgtcaggagc
    19021 atcacgatga acatagcaat gattaaaatc acaccgattg tagaacccat cccccagttt
    19081 tgtgtaacca agaaatgctg ttcgatagcc gttcctaaag tgatcacccg atttccgcca
    19141 atcagacgag tcagcatgaa taaagaaaga gaaggaataa atactgcttg gacaccactt
    19201 ttcacaccat ttaatgataa cggaaaaatc actcgtcgga aggtctcaaa gctattcgcg
    19261 cctaaatctc tactagcact gatcaaagaa ggattcatct cttccaatgc attgaaaatt
    19321 ggcataatca taaatggaat ctcgatatac gttgccacga acagaaaact gaagtctgtg
    19381 aataatatct gtttcggccc gatcccgata aaatcaaaga aatgattcac gctgccgtgc
    19441 acactgaaaa tcccaataaa tgcgtaagct ttaagcagca gattcaccca tgtaggcaaa
    19501 ataatcagca tcagccataa ttgcttgtgc ttcagttttg ttaaaaaata agcagtcggg
    19561 taactgatga tcagcgtgaa aaacgtgatc aaaaatgcat accatacaga attgatcgtc
    19621 atagaaagcg atgtccccga cgtaaaataa gatagataat tattcagcgt gaattgccca
    19681 ttcatatcaa aaaaagattg ataaatgatc attaatacag gcgcgatcac gaataaaccg
    19741 agccacaaaa tataagggac ggaatagatc ctgcgcattg ttttcattct tgtcccccct
    19801 attcttcgta gctgtcaaga cgtgcatcga attcttcttc agactcgttg aaacgcatga
    19861 catggatatc ttctggctca aaggccaatc ctactttgct tccttcttta gcttttttcg
    19921 ttgaatggac catccattca ttttgctgtt catcataaca gatgatttca taatggacac
    19981 cacgaaacag ctgagtatcg accgttacga ctagttttcc tttatctggt gtcgtgatcg
    20041 tcaaatcctc tgggcgtaaa acaacttcaa ctggttcatt tagacgcatc ccgccatcga
    20101 cacattcaaa ttgcttacca acaaactcaa ctagattatc ttcgatcatt acaccgtcca
    20161 cgatattgct ctccccaaca aaatcagcaa cgaaatgatt gattggctca tcataaatat
    20221 ctacgggtgt accactttgg acgattttcc ctttattcat gacaaaaatc tcatcactca
    20281 ttgccaacgc ttcttcttgg tcatgagtaa caaaaataaa cgtgattcct aatcgttgtt
    20341 gcagatcccg cagttcatac tgcatatctg tacgtagttt caaatcaagc gccgataacg
    20401 gttcatctaa tagcaatact ttcggttcat ttacaattgc tcgtgcaatc gctacacgct
    20461 gtctttgacc accagacatt tcactaatct cccgtttttc gtatccagga agctggacca
    20521 tacgcaaagc atcttttacc ttcttttcga tatctgattt ggacattttc ttgatcttca
    20581 atccaaaagc aacgttatca aaaacattca tatgaggaaa aagtgcataa tcttggaaga
    20641 ctgtatttac ttgtcgctta ttagctggca aatcattcaa ccgtttccct tcaaaataga
    20701 tgtccccttc tgtagcttcg gtgaatccag ctataatacg taggatcgtt gttttaccac
    20761 agccggaagg accaagcagt gtataaaatt ttccttgttc gatctcaaaa cttacttttt
    20821 ttaatactgt ttcatcatca tagcgtttca ctacttgatc aaatgaaatg attggtttcc
    20881 ccacgttttt accccctata ttacaaatat gattgcgttg caacaatcaa tacttttgtt
    20941 cgttttttga gatgattcct taattgatgt tgttttgtcg cttgataata gatcgactgt
    21001 cctgcttttg ccacatagac cgtctctcct aagcttaact ctaattcccc ttctaataca
    21061 aaaataaacg tttcagataa tgaaggttca aacgtcttat attctcctgc accttcaaaa
    21121 gtcagcaaga caggctccat ttctttttca ttcgaatcag ccacgagcca ttccaattca
    21181 tacccgtttt cttcatcgaa ataaaccgta tgatcttctt ttgaataaac cacttgcaga
    21241 ttcgctgctt cttgatgaaa aaattcttct ggagtcacac ctaagacttc aagaatagaa
    21301 aagaatgttt ccattgatgg tgaacttaaa tctcgttcca actgggaaat ataccctttt
    21361 gacaaatctg tgcgttcgcc tagttcttct tgtgtcaaat tcttttggat gcgcaaattt
    21421 cttaacttct caccaatttc cataatttcc tccgaatcga agttttctaa tagtaaactt
    21481 cctgtttact accactcgta ttagtatacg aaatttattg aaaaaggcaa ccctttgtaa
    21541 aatttttttt gctgaatatt tctttatctt ttggaataaa ttctagttgt ttgattcttt
    21601 atttttcacc taatttttgt ctaaatttac ggaagaacaa gaataaaaga gtaggcttta
    21661 tggtatgata aaagaaaatt ttaaaaggag tgtctcacga atgaacgctt ttcgatcttt
    21721 tcaggtaata aaggaacctg ttttccatac agcaatcagt gatctgccat ttactgagtt
    21781 ggctgaaaat gaagtcttgg taaaaattgc ctattctgat gtcaattata aagatgcatt
    21841 ggcaatgagc gagtctggtc aggtgatacg aacatatccg atgactccag ggattgattt
    21901 atccggaact gtcgtccaaa gtaacaatcc acgtttttca aaagaagatc ttgtacttgc
    21961 tactggtttt gggcttggcg tcacccatcc aggcggttat agccaatatc aaaaagtacc
    22021 aggagactgg ttagttcctc taccaaaaaa tatgacgctg cgtcaagcga tgatccttgg
    22081 tacagcaggg tttactgcta tgttgtgtgt gaacgcttta atccgtcaag gtatgacctc
    22141 cgataaaaaa gttgtcgtta ctggtgcttc tggcggtgta ggcagtacag cgatagccct
    22201 gttacataaa ctaggattcc agtcaatcat tgccttttcc agaaaagaag agtctgtcac
    22261 atggctaaaa agtctaggtg ctttgcaagt cgtacgacct gatgaatttc tgccagagac
    22321 aacaaaagct ttaggaaaac agcaaatcga ctatgtcatc gacacagtag gtggcgagca
    22381 gctaagcagt cttcttccat tgatctctta taacggtgca gtagctttat gtggcaatgc
    22441 tgggggaatc aaactaaacg cgactgtctt gccttttatt ctgcgaaaca tccagttgat
    22501 tggaattgat tctgtcaatg taccaataga tcaacgtctt tctttatggc aacagatggc
    22561 ggatttgcag attgcagatg aactggtcgt ccaagagatt actctggatc aattgcctga
    22621 aacagcatct aaactacttg ctggaacaca ccaaggaaga acactagtaa atgtaggtga
    22681 ccataaatga agattctaat cacagctgga ggaacgactg aaaaaatcga tcaagtacgt
    22741 gctattacaa atcattcgac aggacgatta gggcaagcat tagctgatta tttagctgcc
    22801 aatccggata ccacaatcga ttacgtgact acgaaacaag cactgaaacc gaaaagacac
    22861 tccaatataa cgatttatac gatcgaatct gcactggact tatttttaca attagaagaa
    22921 ctaacgaaaa aagaacacta cgatgcgatt atccacagta tggcagtcag tgattttact
    22981 cctgctttta gtttttcaga agaacagctg gcaaaaaacc tacccacttc ttcaacgcaa
    23041 gaagaactgg acaattggtt tgcggaaaat gaacagacag ataccactgt ttcaaagatc
    23101 tcttctaaca ccgagcatct tgtgctcgtt ttgaagaaaa caccaaaaat catttcttat
    23161 ctacgtgaat ggcagccaaa agcaaaaatc attggtttca aactattagt agatgtacca
    23221 aaggaatctc ttctggcagt cgcaaaaaat agtctgataa ataacaaaac tgattttatt
    23281 ttcgcaaatg atttgacgga aatccatggc gagacacacc acggctatct cttatctaaa
    23341 gatggaacag tggaagaagc tcaaagtaaa tctgagattg ctgcattgat tactgagaaa
    23401 attagactgg aggaatcaaa atgaaaaaga tcttactagg cgttactgga agtatttctg
    23461 cttacaaaag cgctgatctt acaagtcaat tcgtcaaatt aggtgcccag gtagatgtga
    23521 ttatgtctaa aagcagcaca cattttatca cgccattaac cttgcaatct ctgtcgaagc
    23581 gcgcagtcca tacagacgtc atgcaagaat caaatccgca ggtaatcaat catatcgaac
    23641 tagcaaaaca agctgacttg tttctcatcg cgcctgctac agcaaacatt atcggcaagc
    23701 tagcaaacgg cattgcagac gatcttcttt caacagtcgc aatggcgctt ccagtgggaa
    23761 caccaaaatt gattgcccct gccatgaaca cgaatatgta tcaaaacccg atcactcagc
    23821 gtaatctgga aacattgaga tctgtcggct atcaggaaat tgaaccaaga gaatctcttt
    23881 tagcttgtgg agattttgga aaaggtgcct tagctgatat tcagacgatc atcgaacagg
    23941 tcatgctgac tcttaatgaa agaaatgctt agaaaaaagg agtacttatg aaaaatacaa
    24001 aaaactttac attaactgcg atgtttttag ctattttgat tttattagct gttacgccat
    24061 taggttttat ccctatcggt ccaatcaatg caacaaccat gcatattcct gtaatcattg
    24121 cttcgatcgt tttaggacca agactaggtg cttttcttgg cggtacattt ggactgatca
    24181 gcatgatccg tagcacagtt atccaaacac ctttgtcttt tgtcttttct ccgtttatcc
    24241 cagtcatcgg aacagaacat ggaagctgga aagccttgct gatcgcgttt attcctcgca
    24301 tcttgattgg ggtggttcct tatttcgttt ataaaggtct gcgcaaacta atgaaacaaa
    24361 aagcagattc cgtttcttta ttcttagctg gactttccgg ttcattgacc aatacgattt
    24421 tagtgatgaa tatgatctac tttttattcc agcaagatta tgccaaagtc atcggaacaa
    24481 atttaaatgc tgtttattca gctattctag cggttatttt tacaagtggt atacctgaag
    24541 gaatcgtcgc aggtcttgcg actgcagcag tatgcaatgt cttgttaaga tacttcaagc
    24601 acccttctct tactaactga tagtcatcgt agccgatctc tgattttttt ctcttttggt
    24661 gttactattg aatggaaaga tttgacgtcg aaaggatgat ccaaatgaaa atttttgttg
    24721 taggtgcaaa cggacaaatt ggccgacacc tgataaaaga tttagctcca agttcccatg
    24781 aaatttttgc aggggtgaga gatgttgctt cccaaacatt agtaaaaaaa gagaatgttt
    24841 cgtatgtctc ttttgattta acttggtccg tggaaaaaat gaccgaagca ttcaaaggca
    24901 tcgatgtatt gatttttgct gccggctctc aaggaaagaa tcttctgcaa gtagacttgg
    24961 atggcgcaat caaaacagtg atcgcagctg aaaatgcgca tgtctctcgc tatctgatgg
    25021 tcagtgctgt ttatgcagat gaaccagcaa aatggcctga gtccatgaca gattattata
    25081 ttactaaaca ttatgcagat gaatggctga aacgaactaa cttagatttt gtcattcttc
    25141 aaccagtcac attgactaac gatgaagaag ttacttccat tcaattaact aagcctaatg
    25201 agaaggcatc aaaaacgatc actcgctcta cagttgctgc tgtacttgcc gctctagtgg
    25261 aagaaacgga tatttctcgt acgactctag tactttctga aggtagcaaa gagttgaata
    25321 cagcattcca agaatgggca aaggaggaat agatccatgc gtgccatttc aatcaagcat
    25381 cctggttctg tagatgtatt agaacaaatt gaagtgcctg ttcctaaacc aaaacaaggc
    25441 gaattactga tcaaagtcca tacagcagct gtcaatcgaa cagatattat gaaaagagaa
    25501 tcagtctctt tgaaacctcc ctaccctatt ttgggagtcg aagtagctgg agaggtagtt
    25561 gagaataaaa gtgatatctc cacttttact cctgggacaa aagtatacgg attagtcaat
    25621 ctaggtggtt atgccgaata tgctgtgatg cctgccgatc gtgcaatcct tctccctgat
    25681 acgctagact atgtttctgc tgctggaatc tcagaagttt ttttgactgc ttatcaaaca
    25741 ctttactggc ttggaaaatt acaagaaggc gaaactgtct tgatccatgc aggagcaagt
    25801 ggtgtgggaa cagcagcgat ccaattagct agacagcttt ctcacgcgaa aatcatcgtt
    25861 actgcaggat cagaagaaaa actcgccttt tgtaaagaac ttggtgcaga tgaattgatc
    25921 aactataaaa aacaagactt tcaagaagag gtacgaaaaa tcactgaagg tcggggagtc
    25981 gatgttattt tggatttcat cggcgcttct tactgggaaa agaatttagc ttctatagcc
    26041 gttgatggac gttgggtctt gattggtatg ctaggtggga ccatcgtgcc tgagatagac
    26101 cttggtgtat tgattgggaa acgtgtccaa ctgcttggta cattattgac acctagaagt
    26161 gatcagtata aagcagagct cgcacaaact tttatgcaaa aagctgggcc ttttctagaa
    26221 aatggcaaga ttcggccaat cattgaccgt acattccaat tcagcgcagt caaacaagcg
    26281 catgaatata tggaagcaaa caaaaacatc ggaaaaatca ttttgaagat aactgaataa
    26341 aatcatgctg atcaaaaaag aggctgggac agaagcgttt aactccaaga aataagaaga
    26401 aattcacgaa aattgctttt caaatttttg tgaatttcag cttatttccg aaggaatttc
    26461 ttctgcttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct ttacttttgt
    26521 cccacgctct ttttccgaat aaacggtgtt caaaagcttg catctgcggt aataagtcca
    26581 accaagttaa aaacataaga agctgttttt acttggctgt tcttattact tgatgcaggg
    26641 cagctttttc acaacctctt cactaaacag tgttcaatca gctgaccctc ggtattagct
    26701 caaaacgctg atttcacaac ctctttttat ttacgttcta tttcattcat tttccgaagc
    26761 aaatcgagct gcttgtatgc ccgcttgtcg cccaaaaata atgatctccg caactgaatt
    26821 tccaccgatc cggttgtttc catgtaagcc acctgtgact tcaccagcag catataaccc
    26881 cctaattggc tggttttctt tatctaatac ttcagtgttc gtattgattt tcacaccgcc
    26941 catcgtgtaa tggattcctg gtgcgatttt gatcgcataa taattcggag acgataagtc
    27001 atgttccatg gctgtggcac ggttgaattg agcatctttt ttctccgcaa catccgtatt
    27061 ccatccatca actgtttttg ctagtgtttc ttttggtaaa tcgatttttt ctgctaattc
    27121 ttccattgtc tttccagttg tgacatatcc tttttggtca taaaattcaa tagctgtggc
    27181 acgatcacgc acgccttggt caaaaatcaa ataagctgat ttttcaggca atgctgtaat
    27241 tgctgcagat actttatccc ttgtatccat ttcattgaca aatcttttcc cctcttgatc
    27301 gaccaagatt gctccttctc cgcgaacaac ctcaccaatc aagaccccct catcctgctg
    27361 cacagttgga tgaatttgta ttttatccat atcaacggtt tgtccaccta atttttcaat
    27421 catggtgata ccatctccag ttgatccttc ttgatttgtc gtaatataat cagctaaatc
    27481 gggacgatat ttttcaataa attctttgct ggcaccaaaa ccgcctgtgg taactacgat
    27541 tgcttttccg gtgacctctt ttggttcttc tccttgaaca tgtacagtca cttcattgac
    27601 cgtttcccca tttttcttaa tgtctgtcac atctgcgttg acaaaaatag ggatttcccg
    27661 ctcatggacg ttattcaata acccctccac taagtatcca ccaatagccg agccatcaga
    27721 cggacgatgt gtcctctttt cactcatccc tccagtgatc gttaagttgt ccagtttgat
    27781 accgttttga tctagccaat cgaccgcatc agcagagtga tcgacaaagt atcgaagcat
    27841 ttctttatca ttcgttcctc caccaccttt tagcgtttct tcatagaagg catcattcga
    27901 gtctttgatt ccttcttctt tttgaaattt tgtttctgaa gcattcatac cgcttgatga
    27961 tttagatgtg tttcctccgg caacaggcat cttttccaaa attactggat tcaacccagc
    28021 atcttttgct tcgatagctg ctgccatccc tgcaccacca gctccaataa tcacgacatc
    28081 ataagattct ttcatttctt ttggatctgt atatacttgt tcagaagcgc ctgatgatac
    28141 ttcggcagat tccttcgtac tagaacttgt ctgcgctgta tttttctgat ctgcgccgca
    28201 tgcgctcata gcaagaagtg caacggctgt taataaacca gcaactaatt ttttcatttg
    28261 tatccccctt ttctccttat actatattaa gtgatttttt tcacaatatc aactctgttt
    28321 ttctttaagt catatagctt tggtaaacac acgcttctta gtataattaa ggatatacat
    28381 gaaggagtta ttttatgaat catttgaaaa ccttttttac gaacagtaca aaaactgcag
    28441 gtagaatcac aaacggaatc tatattttat tacgtatcat cgtcgttatt atgctagtgg
    28501 atcaggtctg gaaccaacac tggggaaata caatgctttt attactgaca ttaattttat
    28561 ttgaaatccc ttattttctg gaaaagatat taaagataca gattccaaat atgctagaaa
    28621 tcattttgtt atcttttatt tttagttcaa cagttttagg agagttaagt gatttttatg
    28681 gctatttttc aatgtgggat acttttctac atgcattcag cggattttta gctgggggtg
    28741 tcggcttttc ccttgtttat ttgctcaata aaaatacaaa aaccatgaac ttgactcctt
    28801 tattactagc agttgtttcc ttctgttttt cgatgacagt tggtgttatg tgggagtttg
    28861 tggaattttc agcagataaa ttactgcaat tcgatatgca aaaagatacg atcatccagc
    28921 aaatcaatag tgtggagtta agtaaagacg gaaacactgt ctatcatgtt ccagatatca
    28981 ctcggacaat cattgaaagt caaaatgcag atggtaaaac agataaaaca atcatccaaa
    29041 atggttactt agacgtggga atcatggata ctatgaagga tttatttgtt aattttattg
    29101 gagcagttgt tttcagtgta tttggttacc tctatagtcg aaacgattac caaaaattta
    29161 cgttcatcaa gaattttatt cctaaaaaaa tcaaacgata aaacatgcta aaaaacaaga
    29221 gaaggggcag tgacaatact tttgtcactg ccccttcttt tttgaatgta tggcatgcca
    29281 ttagttatcc gatagtatta actcaaaaaa gtaagatatg aggaatgact atttcgtttt
    29341 ttatcccaat actgaggact tatttcacca tttcgttatt tatctaattt acttaaaacc
    29401 tgcataactt tttcataatc tggattaggt gtgccgtcta gattttcagc aataaaagta
    29461 aaacccattt ttttataaag agcaatcgcc tgatggctcc atgtctgtgt gtgaagatag
    29521 attggtccgt ccgtatggag ggtaggaaat tcttgcaaga ctctggcagt caatgctttt
    29581 gcgagccctt ttccttggta atctggtttc actgctaacc aatgaaaaac cggatacact
    29641 tgctctcttg atttttttcg ccaagcggta caggttgcta ctttttctcc tttttttgtc
    29701 tctacaaaaa acatccttct ttcaagttct tcaggataag gagcaaagtt ttgttgaaaa
    29761 tactcaagtg cttcatctgt cgtttgaaat tccccaacgg aagtctcaat ctccgcccaa
    29821 gcagattcat cttctttttg ataaaatcga aattcaaaac cttccgctaa aggcgtgatt
    29881 ggaacatttt gttgaagtgg tcttgtcatc cagatttctg cgtaaggtaa cgttttatct
    29941 aacatttttc tatccctcct cgtctccatt atgccaaata acatatgact cagctactta
    30001 tttgactata acagatagag atataaatca gaaccagtca tctgcgtcaa attcatttcg
    30061 attagcgtat acccatgttc ctgccatacc tcgcatgaaa tctcctaaag cagaagaagg
    30121 aatacctcca ccaggtgcgg gtgttcccgg actaggaagt ggtacttgcg gctgcagatg
    30181 ctcatcggtg gaatcaatag ttgacaagcg ttttttcttc gtttccttct ggtcatctga
    30241 ttccttctga tcttccgact gtttagcaac aaattctttt tctgattgtt gttttatttt
    30301 aggctctaaa atttcatttt ccaatccaga aacttgtggg gccaaatgag cttcttgcct
    30361 tatcgtttta ttagattctg agatttttct agatattctt gctaactcta ggcttcttgt
    30421 ttgttttact ttccctgttg gagaaactgc atgagccatt tgttgttttt tttctgacaa
    30481 gctttcttct tgtctttttt gttctttttg atctatctgt ttgtttaatg gtaaaacatg
    30541 taatagtgac tgagcatgga gttcttggag tgaatacggg tcatgataac tatacataat
    30601 cgtaaaatca cctgtttgtt tggtcaaata accatcctcc aatggtactt cattgattgt
    30661 aaccgataca tcctttaacg gtacgggttt acctaaggaa tttgttgctg attggatcaa
    30721 ctcttctttg tttatttttt cgtttggatg aacaataaga tcatgacctt ctaatgaacg
    30781 attgtctggt atataaacat aagtaaaggt aatttcccct cctgattgct tcctattatt
    30841 catcagttct gagtgaagta cttcaaggat ctccgaccag tgactttttc tgtctaatcc
    30901 gtttgcttgc atccaatcag aaatagaagt gactttccca ttttgttcat aagtcgataa
    30961 atctatattt ggcactcgat cagaaaattc agcaggtagg cgcaaatcag gaatacgatt
    31021 tacactactc atatgtgttt ctgcttgaag ttctttattt gtttgactat ctataaaatg
    31081 agtgatgaca gtcgatgaag cagcagatgc ttctacataa actacagctg ttgtttctgc
    31141 cacatttgat gttttcgagt ctatataagt taatacaacg ggatattctc ccggagttgt
    31201 agtatctact gtcccgttca ttttgatttc ttctttattt cctgaagttc catcgctttt
    31261 tgttacatat tcaacaagat ctttaggggc gtaactctct cctgttctta agtgaagatc
    31321 ttttcctttg atagctgttt gatcagcacg aacatggatc acagcagatg cagtcattgt
    31381 ttttaaagca attggatcaa aataggacaa ggaaatagta gatgttcctg tattagtcgt
    31441 atccacgata ttcccattgt ttgaaattac tttggacata tctccttgtg ttccatctgc
    31501 gttcttcagc ctttctacca gatcagatat cgaaactttt gtccctgcca gaacatcgat
    31561 tttctttctt tcaaactgtg aataatcttt ttcatataca taagaaactt gtgcgcttcc
    31621 accgtccttt atatctgtca aagcatgatt caaaatatca gtgatctgtt ttaactgatc
    31681 accttttgta ggatcagtca tatcggaaaa gatagaaagc ggcacactgc ttccggtttc
    31741 cgatgtccat aatgttttgt taggaattaa ccagtagtgg tttatcgttg gaggataact
    31801 gactttatta taggaagtca atgcaggaag tagctgtttt ccatttgcat cagtgaaagt
    31861 atgagtaata gtgatagggg aatcagtggt ctcagaaaca gaggtacgta cgaccttgat
    31921 ggtttgtgtc gttgcctgaa cgggtacatg catatagaca cctacagata aactgatcag
    31981 catcgtgcgc atcataaact taacgtagtg tttttcagaa cacgaccgtt ccttatctaa
    32041 acgacaagcg tgtttattta gttgttttga acgtcttttt gaacacattt attcttagtc
    32101 ctccctactc ttgtctaaac atgaagtagt aattttcata agatgatttc attatataaa
    32161 taaaatcaaa agaagatgga ctattaggag agtatttttt ttgatttttt attgtttcaa
    32221 gaaaatcgga ataataactt atgtactttt taattttgtt aagtaatata tctagttata
    32281 tctagttata tctagttacc ttttctttga aaaaaacata aatcagctaa taaatatgtg
    32341 agacaaagct gccatccata aatactagct gattttttca gttaaatgtc tatttttttc
    32401 tctgatgatg gtatttccaa aatattccca gtcatctgga gtcggtggat ttttccaaat
    32461 tatctgttct ttattaaatt tttcaagtaa acaatcagat aaataaatat tcgtacgaga
    32521 agtgattcga ctctcaatca caatattgta atttttaaat cctttcactt gagaaataat
    32581 gtaatcggta taagcagatc cttgcgaaaa atcaatacag acatgaatcg gtgcttcaaa
    32641 atatgatacc ggacaaatac cgaccaataa aaagagataa tcataaaata agcgaatcat
    32701 gaaacgttca tcttttccca agaaatagcg tttattctct tgtatgacct tttggattgc
    32761 tgtactgaat attggatacg tctcgaagaa aaactgtagc tgctttttag acgtaaagct
    32821 agtcatctca aagtcgaata tccaattttt tcgattgaca tgcatcatac ccatacgaag
    32881 ttcttttcgt atatatagtc tttcttcttc agagatttca atcgaaaatg gtaattgatc
    32941 aatcaattcc actgacattt tttgactaat catgtggata tcatgaaaat gagcttccgc
    33001 aagtccaaat gcgccatcta attcaaattc ttcttccgtg atcaaaaaca acatgatata
    33061 agaaatctca tcaatgatct gctctttagg gatatgaaga aaagaaatat gtgataaatc
    33121 cttgatgatc ttcattcctt ctgagctctt aaagtattca tctgaaaaga aacgttttcc
    33181 gattggttga ttcccatagg ccctcaacaa actaatagtg gttagcaaat tgaatttgat
    33241 tcgttttgtt gcagacagtt ttaaattgaa cagatattca aaatattgca cgatactctt
    33301 tgcttcattc atgacgcttt ctctaaatgg catagaaaaa ccattaaaga ccccgaaata
    33361 taccccaaat aatacgttcc gtatgtttat ttcttcccca actaatatgt ttttctttaa
    33421 ctttatttga tgctgttcaa gaaaagagac taattctctt ctttttacat aggctcttga
    33481 tatgcttaaa aaatgattct ctgcaaattt ttcgatcgtt acttttgaat ccacgatctc
    33541 cgttaacagt cgagcaattt ttgatcgttg aaagtagatt cttcttaaat ttttgatatc
    33601 cgtcaaattc agacgttcga catggatctc tgcttcttct gaaatttgga tctctggctt
    33661 tgttttgaat tcagtaaatt ctttatttaa ttctatgata taatttcttg ttttaaattt
    33721 agacaaacct aatgtttcat ataacttagg cagcactaca taattctttt tctcaaattc
    33781 taaatatcta gctagcagca gtttttctct atcttcctct tctataaggt aatccaactt
    33841 catatcctac acctcaaaaa atgcctcata ccaattactt gatatgcaga tgaaagttca
    33901 tcttttcacc tatactgatt ttatgatgga ttatgcttgt tttttcatca gttattctca
    33961 ttttttatct tttttttgag aatattgcaa aaaatggaaa aatttatgag gaaatattct
    34021 atattttttg ttttattgtg ttaaaatgta caagatttgc gccatttgcg taaacaacca
    34081 caaaaaagag caggacggcc accgtcctgc tcttttactt attttaagtt ccattactta
    34141 ttaattggct aaacttctgc ttgtttctga tattgcttgt ttttctccaa tgatccgcac
    34201 ttctgtttct aaagacacat caaatttttc tttgattact tcttggatgt gcgcaatcaa
    34261 ttcaatataa tctgtcgctg tcgcatgatc gatattgacg atgaatccag catgtttttc
    34321 agagacttgt gcaccgcccc atttcaggcc ttgcaatcct gcttgttgga tcagctgacc
    34381 tgtatagtgt cctactgggc gcttaaagac acttccgcat gaagggtatt ctaatggctg
    34441 ttttgattga cgcaattcgg tcaactcatc cattcttgct ttgattgctt cataatcccc
    34501 tgtttgcaaa ctgaatcgag cttccaatac gatagcacgt aattcttgga ctttactgtg
    34561 acgataagaa aataccattt cgtcttttgt caaagttttc aatgttccat cttcaagcaa
    34621 aagatccact tcagcaaaaa catctttgat ctctccgcca tacgcacctg cattcatata
    34681 aaccgctcca ccgacacttc ccgggatgcc gcaagcaaat tcaaatccag tcaatgattc
    34741 tgccaaagct gcataagtcg tatcaatcag tgaggcacct gcttccgcaa tgaccatcgt
    34801 tcctttgaca tgaatctgtt tcatttcagt cagcatgatg actacaccgc gaatcccgcc
    34861 atcttgaacg atcagattgc ttgcatttcc taataccatc caaggtatat catggattcg
    34921 gcaataatcg atgatttgct ttacttcttc ttgttttttc gggaatgcaa ggacatcagc
    34981 tggtccacct gttttcgtaa acgtatagtt catcaatggt tcatcaaaca atatagtaat
    35041 cgtggctaag ctttcaacta tttcttcttt attcactgag gattttcctt tcttttctca
    35101 aacgtcctca ttattctatc acgcttaata caatcttgcc agtcttgttc aaagttgatg
    35161 acggtagtga tctttaagca cttcctcaca taattcatga cttcttacaa cttctttttg
    35221 tttaagcaat tctgtttccg atttacctaa acggatctga gaaaagaagg cctctaccat
    35281 tggctcaaac ccgcgtttga ctagcgtgtt tgtccagtcg ccaaattctt tcactttttt
    35341 tccatcagca tcttgaatga caagctgggt cagatcgttt acttcataag taccattttt
    35401 acttgttact tgatattttt ctatattagc gccacttgct aaatccatcg ttaaaatagc
    35461 cgtttgattt tgtgtttcta attgtaaaat ggcatattcc aaaaattcct ttgtttctct
    35521 tatctggtat tttgttctca aaatgggttc atctaataaa tacacagctg tatcaataag
    35581 atgtaaaaac aaatcataaa ggacgaactc tgtcgtttct tttgccgcta ttcgattttt
    35641 ttgcaggtgg atcaaccgct tatctgggat acgtttcaat tcttctacca taggagcaaa
    35701 gcgccggttg aaaccgatca tcaaaattat ttggttctta tcagctaatt cttgcaattc
    35761 acgaacttca tttagatgga cactcagtgg tttgtcaata taaacatgga taccattttc
    35821 tagacatttt ttggctaatt cataatgtac ttttgttgct gcgtggatca tacatgcttc
    35881 gattttttct tctaaaagct catcgatcgt ttcatataga tgttggaacc cgtactcttt
    35941 ttgaattctt tcttttgttt ctttatttct tgttgcaaaa taaaaatcaa gtgttccttg
    36001 ttttttcgca taagttggta aatatgcttt ttctgcgata ttccctacac cgattacacc
    36061 aatcttcatc tactttcctc ctggatcatt tagttacttt catcttacac cattttttac
    36121 taaaatgagg tacaatagta tcgcaaaggt aaggaaatta attcgaagga gtgtgctttt
    36181 attgaaattt atctcttgga acgtaaacgg gcttcgtgcc atcgtaaata aaaatttttt
    36241 agaagttttt catgagttag acgccgattt tttctgtctg caggaaacga aactccaagc
    36301 aggacaaatt gatttagatc ttccaggtta ttatcaatat tggaattacg cggaacgaaa
    36361 aggctattcc ggcacagcga tttttgctaa aaaaccagca ttgaatgcca cttacggaat
    36421 gggtatcgat atccatgata cagaaggccg tctgattact ttggaatatt ccgatttctt
    36481 tcttgtaacc tgttacacgc caaattctca aagcgaatta aaacgtttag attaccgatt
    36541 agaatgggaa gaagcctttt ataattattt ggaaaatcta aaaaaacaaa aaccagtcat
    36601 cgtgtgtggg gatctaaatg tcgctcatca aaagattgat ttgaaaaact ggaaaacgaa
    36661 tcaaaaaaat gctggattca ctccagaaga aagagcggct ctttctcgac tgttggataa
    36721 cgggtttatc gatacattcc gttattttta tccaacccag gaaggtgtct actcttggtg
    36781 gaactaccga ttcaattcaa ggaaaaacaa tgctggttgg cggatcgatt actttttgac
    36841 gagcaaagat ttagagccag gactagctga tgcaaagatc catacggaca ttatgggcag
    36901 tgatcattgt ccagtagaat tagatttgaa ataaagaggt tgtgaaaaag tcgtttagtt
    36961 tcgagtatta agaaaaattt tgtgaaaatg gctttccaca ttttgcataa atttggcata
    37021 ataccgagaa actggctttt gaacactgtt tatcgagaga ttgtgaaaaa gctgtcctgc
    37081 atcaagtaat aagaacagcc aaacaaaaat agttcctcat atttttcgtt tggttgggct
    37141 tattaccgca gatacaagct tttgaacacc gtttattaag aggttgtgaa aaagctgcac
    37201 tgcatcaagt aataagaaca gccaaacaaa aatagttcct catatttttc gtttggttgg
    37261 gcttattacc gcagatgcaa gcttttgaac accgtttatt aagaggttgt gaaaaagctg
    37321 cactgcatca agtaataaga acagccaaac aaaaatagtt cctcatattt ttcgtttggt
    37381 tggacttatt accgcagatg caagcttttg aacaccgttt attgagaagt tgtgaaatca
    37441 gcgtcctgac ctgagtatta gagaaacaaa tggcaaaata gttcctcata ttttgctatt
    37501 ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagaa gttgtgaaaa
    37561 agtcgcctac tttcgagtcg taagaaattt ttttgaaaat ggttcctcac aactttgcat
    37621 aaatttgact taataccgag aagtcatgat ccccatctaa ctccaaatca caaggaatga
    37681 gttcaaaaac tagcttttct caacaaatat tacataaaaa attctatgtt ttttgttaaa
    37741 tttatttgct tttttcaaaa gtatgttaca gtaatttccc aaggaggttt tacagaaatg
    37801 aattttgttg ccatggattt tgaaactgcc aatcatcagc cttatagtgc ttgttctctt
    37861 gcgctagtca tggtaaaaaa tagccagatc gttgatgaat tctatacatt gatacagcct
    37921 gagactcctt ttttctggcg aaatgtccaa attcacggaa tccatcaaga agacgtacgc
    37981 aatgcgccga aattcccaga agtctggcaa actatccaac catattttca aaaaaatcgt
    38041 ttagtcgttg cacataatgc tgcttttgat acaaaggtct tagcgggatg cttagattat
    38101 tatcatcttg aacagcctaa ttatctttct ttatgtacag tgaaaagtag ccgtcgcctg
    38161 tttcctgaat ttccaaatca tcgattgaac actgtgtgcg aaaatttgaa catccaatta
    38221 gatcatcacc atgatgcatt ggaagatagt cgtgcatgtg cggaaatcct gctttatcaa
    38281 gaaaaaaaat tcgggacaga tccattgaaa aaacttgtga ctataaagta aaagaatact
    38341 tatgaaacac acaaagaggt cgtgagcctg ccgtttcact ccgagtcaca aggagcaatt
    38401 tcaaaaaata gcttctcatg tttattaaat attgtgactg gtgaccgagg agctggcagg
    38461 agaacaccgt ttattggaga ggttgtgaaa aagctgttct gcatcaagta ataagaacag
    38521 ccaaacaaaa atagcttctc atatttttca tttggttgga cttattaccg cagatgcaag
    38581 cttttggaca ccgtttacca agaggttgtg aaatcagcgt tttgacctga gtattagaga
    38641 aacaaacggc aaaatagttc ctcatatttt gccgtttttt gagctaatac cgaaggtcag
    38701 ctgattgaac accgtttatt caaaaaaaat ggactgcgac acgacttttg tcacagtccc
    38761 ttcgtgtgtt tttctgcctt ctcaaaagga tgacagtttc tcactctttt cctatttctt
    38821 ctattcaatc aaataactca ttttatatac atctaaaaat tcacctagat ctgttcttgc
    38881 ccctctaggc atgaccgctt cgatttggaa gcccattttt cggtaaaggt gtacggctct
    38941 ttcattacga acttgaacgt caagctccaa tcgaaaaagt acacccattt ccttcgccca
    39001 actgatgatt tcttctagca taagagtgcc tagtcccatt ccccaatatt cctgcagaat
    39061 actgataccg acttctccca cgtgagacaa acgaaattga ctgtctgcct tgacagatgc
    39121 tgttccaata atcgtccctt catagattgc aagcagcaat aaattattat tgctttcgta
    39181 tatataatcc aactcttctt ctaaggtttc tggtggtaac aggagttctg cttcatccaa
    39241 aactaaaaat tctgtctcct tattaacttg tcccatcatc aaaagaatgt cttttgcatc
    39301 tcctggcact gcttcccgca agatgatccc aacttcttca ctcatgattt tcagcccatt
    39361 tttctagaat tcgctgtttg aaggtttcac tttgctcccc gtatgagatt agtttcacat
    39421 accgcttttc taaatctgta tcactttttt ctaaaatcag ttccaaataa tcctccggca
    39481 gtgcttcttc taatagattt ccccattcaa caacggaaag cccatcacct tcaaaatatt
    39541 catctaaccc taaatctgct ccgctagctg ctacccgata aatatccata tgatacaacg
    39601 gaatccgacc ttgactatat tctctaataa tcgtgtatgt cggacttttg atcatttgcg
    39661 ttatccctaa tccttgggca attcctttcg tcaacgttgt tttacccgca cctagatcac
    39721 cagtcaatat cagattgtca cctggcattg cggaatgacc aattgcctct gcgaattgtt
    39781 ctgtcattgt taatcctgat agttcgatca tttttcatct tctcccgctc ttctttcttt
    39841 ttgccagtat atcgcgtaat gaagtttttt taaagaaaaa atgaactagt caagaacagc
    39901 agctgctgtt tttggctagt tcgcgtgtat ttgttaatca atcaatgttt gtgctgctgt
    39961 gataatcgat aatttatata catcttcttc atttgctcca cgagacaaat cagaaaccgg
    40021 tttgttcaag ccttgtagaa ttggtccgat tgcttcaaag ttaccgaaac gctgagcaat
    40081 tttatagccg atatttcctg actgcaattc tggaaataca aagactgttg cttgaccagc
    40141 tacttctgaa tctggcgctt tcagttgtgc aactgaagga acataagaag catcaaattg
    40201 caattcgccg tcgatcatgt attgtggcgc tagtttttta gcgattttag ttgcttcaac
    40261 tactttgtct acttctggcg atttcgctga gccttttgtc gagaagctca tcattgctac
    40321 ttttggttcg atatcgaaca attctgctgt ttttgcagaa tctacggcga tttcagccaa
    40381 ttcttgcgca gttggattca cgttgatcgc acaatccgaa aagacatatt tttcttgatc
    40441 tcttccacgt accatgatca tcgctccgct tgtccgactg atgccaggct ttgttttgat
    40501 gatctgaagt gctgggcgaa cagtgtcgcc agtcgaatgg atcgctccag agaccattcc
    40561 gtctgcaatc cccatatacg taagcatcgt accaaagtaa ttcacatctt ttaaaatctt
    40621 ttctgcttgt tctttggatg cctttccatt tctacgttca acaaaagtat ccaccatttc
    40681 atcccactta tcgtaattat cagggctgat gatcgtaaag ctagatgttt tgattcctct
    40741 ggcatgcgct gcatttctta tttcttcttc gttccctact aaaatgggtt ccacaagttc
    40801 ttctgctttc aaccgggcag ctgcgcctaa aatacgagca tcagtagctt ccgggaaaac
    40861 gattttgatc ccacggcgaa caattttaaa tcttaaacta tcaaacaatt ccacaagatg
    40921 acctccagac gtttttatat gtattatcat acactattcc agaaaaaaag aacagtttat
    40981 tttatctgta tcagtcaaaa atgctggaaa aattaagttt ttcacataca aagcgaactg
    41041 cactataaca ggaaagcgct gttttattac actgtttcag gcagttgcca atcaatcggt
    41101 tcttctccta acgcaaggag cgcatcattc gttttcgaga agggtttgga accaaaaaag
    41161 ccacgacttg cagataacgg actgggatgt ggagatgtta tgatgatatg gcgactctta
    41221 tcgatcattt tgattttttc ttgtgccggt tttccccaca agataaacac gattggtttt
    41281 tcccgttcat ttaatttttc aatgatcgtg tctgttaatc tttcccaacc tttcccgcga
    41341 tgagaatacg cttgcccttc ccgaacggta agaacggtgt tgagtaaaag gactccctgt
    41401 ttagcccatg acactagatt tccatgttga acaggtgcga ttccaagatc atcataaagc
    41461 tctttataga tatttcttaa cgatggcggg atctttacgc caggttgcac agaaaaagat
    41521 aagccatgag cttgattttc tccatgataa ggatcttgtc ctaaaatcac cactttaact
    41581 tcttcataag gagtcaattc caatgcttca tagatatgat acatatctgg atggatcttt
    41641 tgggacgcat attctttttt taaaaattct cttagatgca gataataatc ttttgaaaat
    41701 tctgaggaca aaacttcttg ccaactgtta tgaatgattt ctttcaaaaa ctccacctcc
    41761 taataaaaag aataactcac attttcttca atcacaaggg acaatcttca ccctcagcac
    41821 ttgattaata tggtaaacta ggaacaagaa gcagaaagga acgataatca ttatgatcaa
    41881 attaattgca tcagatatgg acggcacatt attagatgcc catatgagtg tttctcctga
    41941 aaatgccgag gcgatacgtt ttgcaaatga tgccggtgtt gagttcatgg tcgctactgg
    42001 tcgaaactat caagaagctc gcgcagcttt agatgaggta ggaatcgatt gtgcgatgat
    42061 cactttgaac ggggcacagg tatttgataa agaaggaaat tcattgttta ccgtgtcgat
    42121 tccaaataat caagcaatct ctgttttaga tattctagat gctaacggta tttactatga
    42181 agtagcaacc aacgatggtc tttattctga aaatcaagcg aaacgaattg aaagttttgc
    42241 ttccatggtg gctacccatt tacctcacct tacgtataaa atggcgattg ccatggcctc
    42301 agctaagctg gagttattgc acatcacata cgtggacagt attcgtgcta ttttggaaga
    42361 aaagaatctg gaagttttaa aaattatttg ttttcataca gaagggccag ctgtattagg
    42421 tccagttgga aagcagattt ctcttttagg cgatctagcc gttacttcct ctggtcaaaa
    42481 caatatcgaa gtgaaccata aaaacgctca aaaaggaatt gctgttgccc atgtcgctca
    42541 cgagcgtggg atttctttag aagaagtcat gacgattggc gataacttca atgatgtcag
    42601 catgctgcaa gtagcaggag tcagtttcgc aatgggaaat gcagaaatcg aagtaaaaga
    42661 ttatgccaaa tatacaacgg acacaaacct tgaatctggc gtaggaaaag ccatattgcg
    42721 cgcgattgca gaagacttgt agttttatct agaaaagagg gatatagatg tcagaatttt
    42781 tcattcagga aaagcagctt ggacgtgcaa ctcggacaat tgtcaaaaac gaaaaaggac
    42841 attccctgtt tttgatggtt ggtcgctggg gaacaaaggg cgatgcattg tctctttatg
    42901 ccatgaatgg cgatctcgtt gctcacatca agcagataag cctgacattc ggtacgcgtt
    42961 ttgagctgta taaagagttc gaaaaggtgg gaaccatgca gaaaatattc aattggcccg
    43021 gtgactttta ttatattcgt agacttcact ggacagtcca aggtgatatc tataatcatc
    43081 aatatcaaat ccatcatttc aatcagcaaa tcatgaaaat ggataaagca acactttttt
    43141 caggagatta ctatgtattg gatgtctcaa atgatgaaga tgctccagtt tgtatttgta
    43201 ttgctgcggt tttagattac tggctctacc gtaaagacaa aagtcgcgat aagcctgttt
    43261 cttaccgact taacttaagt taaaaagatg tacctgaaat gcggaaatac gcatttcagg
    43321 tacatctttt tagatattct tttgcatatg atcataaaga tgaccactga tcatccgctg
    43381 accgacaact ttgaagtcat ggcgttcgta taatttttta gcctttggat ttttttcatc
    43441 cacacttaga ccgatgacgg agcgattagc tttcttcgcc aatttaggta atgcttctaa
    43501 taatcgcgaa ccgatgcctt gtcctctaaa atcttctgat acactgatag agtccaaata
    43561 ccattcgttg ggaaacgttt ctttatcaat gaacaaacgt gtagacgcat ctagctgata
    43621 tttctctaag ataggtacca gtggctgatc gatgattgat tcttcttcat ctgtataacc
    43681 gtaagcaact cctgcaactt taccgtctat ttcttctacg atacctcgtg aataactgta
    43741 acgataattt ggatcagtga ttgcttcttc taaaatctct aaagtctttt gttcccctgt
    43801 ctgcttcaaa aatggcagtt ccatatcttt tagaatcact aagatcaatg gggcgatttc
    43861 tggagcatct tcttttctcg caaaacgaat catagtttcc tctccttttc tccattctaa
    43921 catgcagaaa aagaaatcgc aaaatcgtta ttttaaaaaa tcttcaatct tttcagtaat
    43981 gaaataacca tgagtaacga ttcttgccgc ttcagttcgg caataagggc agacgactgg
    44041 catttcttta tcattatgtt cgactacatt attgacttct tcgtatgcaa atttttttcc
    44101 gcaattaggg catttcattt tttccatgtt atctcaactt cctttcatct ttactctctt
    44161 agcttactct tatattgtaa aaaagagaag caatatcctt cttctatgca gatatccata
    44221 cctgacggtc ctgttctcca tctattaatc ggactttata ataaggacgt tcatctttga
    44281 ctagaagtgt ccactctttc acttttgctt ttttcccgta gtagctgact gcttccttca
    44341 tcgctgcttg cggttgtttg aactcttccg ttttttctat atcaaaaaga tgttctgcgg
    44401 ccttttccgt gtcatttcgt acggttgttt tcccagtgga tggattgact gctatgactt
    44461 gtccttcaca aaaaaactgg tattcatatg ttgcattcgt aggattctcc aaatcttttt
    44521 caactgcaaa atgaatagca gatatgttat gttcttttgt ttcgtttttt acgattgctg
    44581 ctgctttttt caatgagatc cgatattcct ggtcactaat atcatccatg tgaaaagcgg
    44641 cattgagcag tcccgtcata ccggtaatcc ctattacgat gagggcagca acaccaaaca
    44701 tcattttttt cattcttcat tctcctgttt ctttttttta aagaatatca agaaatgaac
    44761 gaatgaaaaa tcgaatgaaa cgaaaaaaaa gtgacaattt tgttatcttt attcgtgcag
    44821 ttctaatggc aatccgtctg gatcaaagaa aaacgtcatt ttttttcctg taaaggtatc
    44881 ttctctaatc ggttctgatt cgatccctaa ggactgcaat tctgcaattg tttcttcaat
    44941 atcgtctact ttgaaagcaa gatgacgcaa gccacaagct tctggatagt ttggtcgttg
    45001 tggcgcatta gcaattccaa aaatctccaa ttcagcactt cctagtttca gatctaattt
    45061 atagtcatct cgttctttgc ggtaattttc tctgattact tcaaatccta atttattaac
    45121 ataaaaatca cgtgatttct gataatctga aacaatgatg gctatatgat ggatcgttgt
    45181 aaggttcata tgagcactcc tattcttcgt ttaagctcgg atctatatta atctccagtt
    45241 ccattgtaaa tgtgtcagat tgaaaaaaat agctgttttt cctttttata agaaaaaagg
    45301 caaaaaaaca gaaagtaggt cctccaagac actcttcctg ttcccaatat aataaatgaa
    45361 agtaagaaat tatattttca agaaaacaaa cagaaaatta tcataacaca aattatttat
    45421 aattgaaaga ctagtttttt ttcaagaaaa gcatacaata gattgtgtta gtaaatacag
    45481 aacacactac atttagtgtc ttaaggagtc ctcatacatg aagtcatatt ttcagttttt
    45541 agctcatcag ctaaaaggct ggccgcaaca aaattattat cttttctttt tcagtcttgg
    45601 ctgccaggtc atgactcttg tcaatagtcc catcacttgg ctgtccgtta ttacatttat
    45661 cggtaccacg cttggtgtat tgtgtatttt atccatcaat gcggcaaaat cagtcaacgg
    45721 tattttaggt attttgtctg cgatttgttt tattatcgtt gggttttcag caaagaacta
    45781 tttaagtatc ggtgaacaga ttgcttatat gatcacattg gatatccccg tattgttaag
    45841 taaagaatgg aatcataata tggcttcaaa aatccgaaaa ttcactggaa aaagctggtt
    45901 tatcgcaatc atcagtactt tccttgtcta tcttgtttca ggattcctga ttggtcgtta
    45961 tacagatgat cctcggccgt gggtagatgc cattgctttt tctattagct tgactgctgg
    46021 tatcatcagt ttcttgcgtt acaacaacca atattactgg tggttagctt cagggcttgc
    46081 tcaaatggtc ctttggtata tttcatttac gcatggatct gcaagtttgg cgatgttcgt
    46141 gaacagctct gtttacttgc tgaatgatgt ccttgcattt accgtttcac cttggtataa
    46201 ccaaaaagaa cgtgaacgta tgcaaaaaat ggaagaagaa tactacaacg cacaacaaca
    46261 cgcataaaaa aactgagcgt gggacaaaag taaagaacac ttttgtctca cgctctaaac
    46321 acgtataaac ggcggaatca gaagcaactc cttcggaaat aagctgaaat tcacaaaaat
    46381 ttgaaaagca attttcgtga atttcttctt atttcttgga gttaaacgct tctgtcccag
    46441 cctctatttt ttatagtaat tccttcagat actttcttgc ctcatcattg aaacgcagtg
    46501 attcttctaa cttctgataa tattccaacg cttgtttctg agcttcagta aaacgataat
    46561 gttttccttt ccatttgtcg attgtctctt gcacatttcc agattggata tctttcacta
    46621 ctagttgcca tttttctttt gagactgtac ggtctttctt atcagcagat tgtatagctt
    46681 ctcgttcttt acgcaatact tttaaaaaac catttctgac tatccgagga atgctgtcga
    46741 agaacccttc tgtaaaacca tagcgacaat attgcttcca aataaataga tagatttttg
    46801 gttggatgaa tcgttggttt ttcgcaaaat attccatctg agcagtgact tctggtgttc
    46861 gttgacgttt tgtctttctc aacacggaaa taaatgtttc aaaataagca ttaggatgta
    46921 ctggcacttc ttcatatacg atggattgcc aatctttacg taaaaatgcg cgatagttga
    46981 tcaagaattc ttctacatcc tttactaatt cttctgcaaa gtcgtcaaat agttcttttt
    47041 ttatctgtcg cttttttgac tgcccattga tgtgttcact tattttcttg atttcatttt
    47101 ccaatgcttg ataatccgct atgtaaatcg gcatttctac ttggcgaaat tctgcgagcc
    47161 gctgagctaa ttttatatcc ggtaaatatg gctgtttcat ccgacgattt tggtacaaga
    47221 caaaacagta tttttgccat agtccttcag gaaaatcgat attcttctgc ttaagccata
    47281 ataattcgtc taaggccaga tcaacttttg tcattccctg atggatcgaa gctgccactg
    47341 tcggagagac atgcaggtga tcggcaaagt ggttgatgcc tagttttagg atctttccgg
    47401 tttttggcga tttaacgatg tattgcactt ttaattctct accacactca caatacaatt
    47461 tttgctggct tcgttttgtt cgaaaaaacg gattgatctt gaagtcagaa aacacccaat
    47521 ctgttgcagc taaataatgt tcttccataa aacgagagct gattagatat cggcggtgct
    47581 tatcgactag ttcccgctgt tttttcgtta attttgcata gatctcccaa cgttgactgc
    47641 ttgtgtattg tttagaaatt ttgatgggat agcttttgct gatttctttt ggaaaccatt
    47701 cttcaaagac ggattgccat tcttccacgg ctgtttcttt cctttctaat tacaaaaagc
    47761 tggctactaa cataacgtta gcaaccagcc agtgtttctt gctaaattag tgagttgttc
    47821 cggcatttcc ggaaatatct tctttatttt ctactgctgc ttcaactgca taagtcaaag
    47881 aagaagcaat gtcttctaaa gacatagaag gcgtacccac tggacgatcg atcacttgat
    47941 cgggtgagaa tggcacgtgg atgaacccac ctcgaattgc cgggaattgt gtttcgatca
    48001 aatgaagcaa acgatacatg atatcattgc agacaaatgt tcctgctgta taagagatgt
    48061 acgctggtag accatgatct tgtacatttt ttgtcattgc tttgattggc aatgaggtaa
    48121 agtaagcggc tggaccgttt tcttctaaag ccgtatcgaa tggctgattt ccttcattat
    48181 cagggattct tgcttctgct agattgattg cgacacgttc gaacgagact gctgaccgcc
    48241 cacctgcttg tccgacacag atcacgacat ctggttggtg ctgttggatg gcttctttga
    48301 ctacttgact gcttttttcg aatacggtcg gtacttccac tttgatgatt tcagcaccgc
    48361 tgatttcatc tggcattttt tttactgctt cataggctgg attcactttg tccccaccaa
    48421 atggatcaaa acctgttact agtactttca tctgttgttc ctccgtccga ttgatttaac
    48481 atatggttat cttttatcat accattttcc ttgaacagcg taaataaagg aaacaatagt
    48541 ttaaataaca taacagatca aacttaatat attcttataa aaaaatagtg ttccactaca
    48601 atgttagaag aggttgcgac aattattctg tcacaacccc tctcttctat tatttaaata
    48661 gaatcatata agcaatttgg aaaactagca taaataacgc aataaacaac tggtttttga
    48721 tcactccgta tttgtctttc atctccagca tcgctacagg cacgatattg aagttagcag
    48781 ccatcggtgt cagcagggtc ccacaaaaac cgcaagtcaa tgcaaccatt cctattaacg
    48841 ctggattcgc tccatgacta aatacgaatg gtgcaccgat cccaaccgtc atcacggtga
    48901 tggccgcaaa tgcattcccc atgattaccg taaatatcac catgccaaga gcgtaaatga
    48961 tgatgccgat gttcacattt ccttctggaa cgatcgtacc tactgcattg gaaatcactg
    49021 tcccaactcc agcgcttgta aataccgcac ctagagaagc taaaagcatt ggcaacatgc
    49081 ttaacggccc tactgtgccc agcatatctg ctgcatcatc taaaaatgta cttggtcgat
    49141 tatctcgaga aaagaacatc aagattagca tggctgcaaa aacaccgacg cccacgccga
    49201 ctaaagcacc taaattggta aatagagcaa acaagatcgc aaagacaccg atactcaaag
    49261 ctggaataaa aattttcatt cctagtttgt ctgacatttt ttccatatat tcttttgatg
    49321 gaagccggct ttctcctttg ctgactttct tagcaattgc tggtatggtc atcgcaaaga
    49381 tcaagccacc gttcacgatt gccggaagcc atcttcctcc tgcaataact acccctaaga
    49441 ccgtccagaa aaaggctgac ccataacgat gaggattggt tttatctgtt aaatttctta
    49501 ctccagtgta aatcaatacg agtcccatca cgatataaag gatctccagt aatttatcgc
    49561 ctaataaaat atcaggattt gtaaaaaagt ccatcttatt gcccctttcc tggataatat
    49621 ttcttcgcta atttcttttc tttaagatag aagtagacac ttgccacaac taaagccgtg
    49681 atagccactg gaacttccac taaagcaagc tgtcccaatg ttacgtcata tcctagatct
    49741 ttcagtgttg attggactag caacgcccct gctcctccga tgaatagtac ttggccaaag
    49801 aaccagcaga cattttccat agctgaagcc atacctttta gttcttcttc atgcttagga
    49861 tggacttcta acccttttga ttcgatggtc cccaatgcca tcggtaaaat gattggacga
    49921 acaaatccag caactccacc aaaactcacg ttaaaagccg caaagatcat tcgaaagatc
    49981 ccataaatat ctacaatcat accagcagat actttcttga atcgcttgat caaggaagcc
    50041 gctgattctt tcagaccatt tctttcaagc gttcctgttg ccaacataat gatgataaaa
    50101 atcgccatcc cgcgattgtt tacaaaactt gtacctaaaa gttctaacat tccttgaatg
    50161 ccaagaccgc cagtcaaagc tgtaacaact aaagcaacca ttacgatcaa tatcgagtct
    50221 aatttaaatg caaacccgag aataacaatc aagacgccta aaaggctaag ataattttcc
    50281 atatattttc ctccataaaa tgacaatatt tttttaatta taaagcaaaa cacataaaaa
    50341 atatagttgt tttctcacga aatagacact atttttaaat atttttcgtt atttttttat
    50401 cacaaaaatt atcttactta ttgtaaggta aagctttttt taatttattg cccgataata
    50461 tatagaaata aggtctagtt actgtttttt ttaaatgatt aataaataac aacttctttc
    50521 tatgaaattg caaagcattc atcttctttt ccgctaacga tatatccgtc agtgcttggt
    50581 acactttact aaaaagtatg agattgccga tatctggata ggtgtgctat actacagaaa
    50641 aagatataca atctgccacc gggtaggata aagaggatga tcattccatt aggtctttga
    50701 agggatgatt ttcctctttt tgtgtatttt tttatagtta aggaggaatg taagtatggc
    50761 atggatggaa ttaatcatag caggaatttt ggaagtattc tggtcaacga tgatgaaatg
    50821 gagtgatggt ttttctaaaa tcaattattc tttttacaca gtgattggca tgattgctag
    50881 tttttacttt ttgtcaaagg caatcaaaag tttgccgatg agtctctctt atcctatctg
    50941 gacagggatt ggcgcagttg gttcggtcat aattggtgtg gtcttgtttc atgataagct
    51001 gaatctttcc acttggttct ttgtggggat gctactcatc agtatcattg gcatcaagat
    51061 tactagcggc cactagacac ttggaataag tactgatcag aaaaaataag cctttttatt
    51121 taatattcaa tttttttatg aaaaaataag aaataagtcc aatgacctag cgacttctcc
    51181 actcatcagg tgtatgcttg tactatctat agaaaaggag tgaatatttt tgaaaagtct
    51241 ttcggtccaa gaattatcca agaactttgg tcacaaacaa gccctcagcg atgtcagttt
    51301 tagcttatcc cctggcaaaa tcgttggatt agtaggtcct aatggcgctg gaaaaacaac
    51361 gatcatgaaa gctattttag gactgatcca ttactcagat ggaacaatct gtattggtga
    51421 aaatgagatt tctccctcta gtcataaagg gttggaacaa gtaggagcat tgatcgaata
    51481 cccgggtatc tatccattct taacaggcta tgatcatctg aagttattct ctgaaaccaa
    51541 cgatgtatct gctatcgaca ctatcgtgaa tcagctcaag atggaaaagt acattcacaa
    51601 aaaagcgaaa tcctactcgt tgggaatgaa acaaaaattg ggaattgctc ttgccttact
    51661 gaaccatccg tctatcgtta ttttagatga gccgatgaac ggtttggatc cacaagcaac
    51721 aagagatgtg cgaaaaatca ttaccgactt ggctactcag ggcacctctt tcttgatctc
    51781 cagtcactta ctcagcgagc ttgaaaaaat ggtcgatgag ctgatcctga tcaatcaagg
    51841 aaagatcatc aaacaatgta caatggctga attgaaccaa acagcgcaag atttcatcgt
    51901 tatctctaca acaaatgatc tagctgctcg aacgatcttg acagaagctg gatatacttt
    51961 ggaagatcct gataaaatca agcttttaaa agaaaacgaa gaattattag gaaccgtgat
    52021 ccagctattg tctgcacaaa atatccatgt gacagacgtc cagcatctga cgaatgattt
    52081 ggaatcttct ctattggaaa ttctggattc agtaaagggg gaagaagaaa aatgacattg
    52141 cttgtaaaac aagaattatt taaattgatc aagaaaaagt caactgctgt tttatctgtt
    52201 ctattagttg ttttgctcat aggaacagca cttctagcca aaaaatacac gacgatcatt
    52261 gatccagttg aaatgactgc tcagcttttt agtgccacat cttggattgt ctttatcatg
    52321 attgcagctg caagcacgat catttcgatg gaagcacaat atggtacatt gaaaaatctc
    52381 ctttatcgaa agtattctcg aggagaaata ttagtaagca aatggatcac attagttatt
    52441 tattctgttt atttatacct tttagctatt attgtcactg tgttgatgaa actgattctt
    52501 ttcccttcga tttccttcac ggagaaggtt tctactggtc aaacactgat ccaaagcttg
    52561 ttcacttata ctttgggtag ttatatcggt ttatggctga ttttaagttt agtgttgatg
    52621 attgcttgct ttatcaatag ttccggcgca tccatctcag caggaatcgt cttttatttt
    52681 gcttcgtcaa tcatatctgg tatccttatt gcactcatcc aaaaatggga gtggatcaaa
    52741 tggaatccga tcagtatgtt gaatctgcaa aaccaaattg gaaacgaaga gatcatgaag
    52801 caattgactc atctttctac taatcaaatg ctattcggta atttagctta catcgttttg
    52861 ttcttagcat taggatatct cgtatttaag cgaaaaaatg tatgatgact catcaaaaaa
    52921 gaggctgtga aagagacgtt cagccttatt gccgattggc tgtctcttaa acaccgttta
    52981 ttctgaaaaa ggagctgtga caacatttgt gtcacagctc ctttcctagt atgtttttga
    53041 ataaacgaca ggctcacaac ctctctttat acttctttta tacttctata cgtgaagcat
    53101 cccagtggca aataaaacca ttgcaatcac tccgaccatc gtcacaccta taagtaaaat
    53161 cttatctaag tggatatgtt gtacaggctc gttttgctcc ttacgtgctt tgaggtaaaa
    53221 ataaatgcct ggcaagaaaa gaacaagaac aagcattact tcattaaagg ctacgactag
    53281 catagcccat acttgaaagg cacttgctaa aagccctact aaaaattgga cccattcttt
    53341 ccgctgataa gaaagtttca tttggtacaa tcctaagaaa agccacgtga agaaaatagc
    53401 tgctgtacca agtgtgtaag caaagttata agcactgtca gtgaataata atgaaagtaa
    53461 aaagacattc gtacataacg tcgtcaatac gatagcataa gttggtgccc catttttgtt
    53521 gagttttccc catgctttag gcaaaagtcc gtcttcagcc atgtttccca ttgtttcaat
    53581 cggtaagatc gtccatgaga gccaaacacc aactaaagaa atgatcaaac cgccgttgat
    53641 cacgactgct ccccatttac caaccatcat ttcaaacaca tagcccatag caggctgcgc
    53701 cttgatcgtt tgcagctgat tcatcgtcat tgtcccatat ggaagcatgg aaaccaagac
    53761 gtaaataata atcaagccga atatccctag aatcgttgct ttcccaacat ctgattgttt
    53821 ttttgctcgt gaacctacga cagaggctcc ttcaatacca acaaataccc aaagcatcac
    53881 catgatgcaa ctcaatactt gactggaaaa cgggatcggc tgtccattcg cattcaatat
    53941 aatgtcgcta gaaaagttat caatgaattg ttggatcgaa aacgtgctga tagctactac
    54001 aataaataaa aataatggca ctaatttaca gaatgtgacg atagcattga cgaaactagc
    54061 attttcgact ccccgattca ctagccatgc atatccccat aaaaagactg tactcatcac
    54121 gatcgatgcc agattttgcc caccttcaaa tactgggaag aaatatccta atgcgctcat
    54181 caacaatgtt gcaaaagcta cgttgcctaa ccagcatgtg agccagtaac cccaaccgct
    54241 gataaaacca gcgaaacggc caaaaccttc ttctgcgtaa ctaaagatcc cgccttttaa
    54301 atctggacgt tttttattga tattattgat cgacaaggag agcatcaaca ttgctgttcc
    54361 tacgagtacc caactgaaaa tagctgggcc gccagccgat ccggagatgt ccgtcataat
    54421 accaaatacg ccacctccaa tcgctgaacc aattactaag gcagcaagtg gaattaaacc
    54481 aattcctttt ttctgttgct ctgtatccat gtaagcatcc tccaaaataa aaccgctttt
    54541 atcaaaaagt ataacaaacc ttttttattt ttacttaatt aataaaaact ttaatagaaa
    54601 tataattcta ccggcttttt tctcattata caagcaaagc gcctagtccc tttccaaatt
    54661 acaccaccaa aaaacttaaa aaagatgcta tactaaaagg aaagaattgg aggatgatcc
    54721 atgaacattt tatatatatc gatttcagga aatacgcgtg cctttgccaa acatctagca
    54781 gaatatgctg aaaaaatgca tgcagaagat cctgtcaatc ctgaagttac tttaaaagaa
    54841 atccatgaaa atagtgattt tacgaaagaa acagaaccat tttttacttt cgttcctact
    54901 tatttagacg gcggaaatgg tttagataac ggtgatacag aaatcttgac cgaaacgatg
    54961 cgtgaatatc tggaacatga agacaatcat aaactttgtc ttggtgtagt cggtagcgga
    55021 aataaaaact tcaataatca gtattgtcta acagccaaac aatatgcaca aacatttggc
    55081 tttcctttct tggcagatta tgaattacgg ggaacaccat ctgatgtgac acgaatttat
    55141 cagattttag cagaaaacaa taaataataa aaaagaagaa gctgaaaaat agatttcagt
    55201 ttcttctttc gtttctattg tttctatcat attaagcttt gacatccatc acaggtgctt
    55261 ttgcttttgc tttacctgtt ttttccaaga caaagttttt tacacgatcc atattggtta
    55321 ccaagacgat catggatgtt tctttgcctg ctgctttgat cgcttctaag tcagcttctg
    55381 ctacaagcgt atcaggtgtc acttgctgcc cttctgttac tttcacatca aatggcgtac
    55441 cgcctaagtc aactgtgttg attcccatat gaagcaagat ttctaaacca tttggcgttg
    55501 tgatcccaat agcgtgtttc gttgggaaga cagagctgac taccccagta actggagaat
    55561 agatatgtcc gttttctggt tctacaaagt agccttcacc catcatcttt tgtgcaaaaa
    55621 ctggatcact tgctttatct aaagaaacaa ctgttccgtc agcaactgat gagaggatag
    55681 tcacactttc agctgaagtt tgaggtacta ctttttcagg cacttcattt actgtggctg
    55741 tttcagtcgc taattcttct ttttctaaac ggtctttagg aataccgaag aagaatgtag
    55801 caacgaagcc accagcataa gctgccaata atccaaggat gtagcctaac catttaccgt
    55861 cagagatcaa tgggatcaaa gcggctcctg aaggtccaat agcgatagcc ccgacatttc
    55921 cgatcattcc gatcactgcc ccgccgatac ctccaccgat acaagcagta ataaatgggc
    55981 gtcctagagg taatgttact ccgtaaatca atggttcgcc gattcctagg atcccgactg
    56041 gtaaagctcc tttgatcatt tctgttaatt ctttatcttt tttgcagcga atccataatg
    56101 ccaatgctgc acccacttgt cctgcaccag ccatcgcaag aattggaagc aatagcgtac
    56161 gaccagtttc atcaatcatt tgcacatgga ttggagtcaa aatttgatgc agtccgaaca
    56221 taaccatcgg caagaataat gtgcctagaa cgaagccggc aaatgctcca ccaacgccaa
    56281 gtacccagtt gatcccaccg accatgccat cagaaatgaa acctgctaaa ggcatgatga
    56341 agaaaatttc aatcagaccg atggcaatca atgaaagagt tggtgtaacg atgatatcta
    56401 ccgcatcagg tactacttta tgcagttttt tctcaacgat tgacaatagc caaacagcga
    56461 agatgacacc taggatccca ccttgtccag ctgcaagagc ttcaccagta aataagtttt
    56521 tcagtggtgc ttccggattc atccctgtca gcatcacaac ggccccgata actccaccaa
    56581 gagttggtgt tgcaccaaaa acttgtgcag cattgatacc tgtatagata actaggtagc
    56641 taaacatccc gtttttcaag atgttcatca catcgatata ttgttgccat gttgctgcat
    56701 caagtgttcc ggctgtgact aagtttgcta aaactgcggc aatccctgcc acgatcccag
    56761 taccgacaaa tgcaggaatc attggcacaa agatattaga aatgtctttt aataccgatt
    56821 tgattttaga tggtttttgt ttcgattttt gtgccgcttt catttcttgt gcccgttcgt
    56881 ttacacggtc ttttccagat gctgatgaat ttgctgtagc tgtacttaca gaagaaagtt
    56941 tttctcctaa tttcacgcct gccaaatcaa ccatttgctg tgctactttg ttcactttcc
    57001 caggtccgat gatgacttga agctgttcat cttctactac accaagcact cctggaatcg
    57061 cttttaattc agagacattt acaagatcat cattgatgat cttcatacgc acacgagtca
    57121 tgcagtggac aatgctttct acattgccca tgccgcctgc ccctttataa atttgttttg
    57181 ccagttcttc caaagtcagt tcgttttttg ccatggtctt ttccccctca taaggtccct
    57241 tttacaaatc cgtttgcttc agctaatttt gcttgagctt cctctttatc actatttgtc
    57301 aaaatcatga cgatagccag cttaacattt tgatctgctt cttcaaagta cttttcagct
    57361 gtttcgtaat cagcttctgt cgcttgcatg atgattcgtt ttgagcgttc gattagtttt
    57421 tcatttgttg gtttgacatc gaccatcaag ttattgaata ctttacctat accaatcata
    57481 ctgatagtag aaatcatatt caagataagt ttttgtgctg ttcctgactt caatcgagta
    57541 gagcctgtca aaaattctgg acctgcatcg acttcgattg ggaaatccgc gtgtttactg
    57601 atttcggctt gtttattgca agaaatcgtt cctgtgacag caccgatcga ttttgcgtaa
    57661 tctaatccac cgatcacata tggtgtacga ccgctagctg cgataccaat aactatatca
    57721 ttttttgtca aattcagctt gattagatct tcttgcccta gctcataaga atcttcggcc
    57781 ccttcgacag ctacagtcat tgcttcttct ccaccagcaa ttagacctat gaccatttcc
    57841 ggttctacac cgaatgtcgg tacgcattca gcagcatcta acacacctag tcttccactt
    57901 gttccggctc ccatataaat cagacgtcca ccttttttaa aggactcaat cgtgttagca
    57961 atcactggtt cgatacttgt cagttctttt tcaaccgcag cggccacttt ctgatcttct
    58021 ttgttcatta gttgaacggc ttgagaaata ctcatctcat ctaatccaaa agtttcttgg
    58081 tttctgcgtt ccgttgttag gttctctaaa ttgattttgc tcatttttat cttccttctt
    58141 ttcttataaa ttgatagttc ataccagctt tgatttggtt gatcaatggt agctcttctt
    58201 tgataacttt agctactaca ttcacttttt catccgctgg caaatcatat ttggttaatt
    58261 ggatctcacc catatagcgc aaatactttt cgttatctaa agtaatagac cctttcatac
    58321 gcgtagctgt atttcttgct gggataggcg gaatctctcg aaaacgtgca tctacgcttc
    58381 gtatgacatc tcttgcatcg tcttgccgat tcgtatgctt ccctaatata tattcgtaaa
    58441 attcttcatc tacaggttcc gtatggagca agactgtctg ttctttttgg aaagaagcaa
    58501 attgctcctg aacgttttct gacagacctg catctccgat gtaaacaata tccgtgttac
    58561 ttgctaatag atctagagcg cctgcaagag gatggatccc tcgatgttct tccaaagttg
    58621 gcaatccttg atatagtggg cctctcaact ctgtatctcc tggtacaaaa ccttggacaa
    58681 ggagaccttg aattttgagc cattgatttt ttttctgata ccattctttg tccagccctg
    58741 tttcgggacg tggataataa ttatgccaag cttcaatctg tgagaaatca gcttctgctt
    58801 ctttcaattc atcgatatct ttaggcgtga tcgtgctagc attcaaactg attttcaatt
    58861 gatgtgacca gtcggcaatc tgctgattgg aaatatgata atccattctt aaacctgtta
    58921 caccaattgc tttcaaaggc gttagatctt ctaatgaaaa acccgctcgt tccaatgcct
    58981 ctcctgaaat atcgaccatc aattctagtt tattcttttt cgcttcgctt cctagttcga
    59041 tcaatcgctt ttgatatgcc gaaacatcat cttctggtat atgcatggaa gtgaaaatac
    59101 cgacaaagcc attggatgcc atttggcgga tatactgttt cttctcttct gacaaagaat
    59161 cgttcataaa tattgaaaag ccaaacatat tatccctctt tttctgtatc cgtcttcatt
    59221 tctatgacta gagtatatat ctaaagaaac aaaatttcaa tacttttatt aaaataatta
    59281 aatttcattt ctaaaggttg agtttatatt atcaaaagaa ttgtcataac ctaaaaaagg
    59341 cactgctaag caaaagcagt gccttgaaat attttattta aataacacaa aaacataatt
    59401 actcataaga aaccaattct gtattatcta ccatgaatgt aaagaacccc tcattaggca
    59461 tcggatgaaa ataagcattg atcactctta tcaaggcatt atggcaaact aacagataga
    59521 cattttcttc gtcttcgatg cattctttca ataaaggaac gatccgtgca tacacatcta
    59581 agactgactc cccatttggg aatcgtacag cgaacgctaa acgtgctttt tgaaagttct
    59641 catctttgct tggcagtcca tcataatccc caaaatccat ttctaccaat cgttcatcaa
    59701 cggtcagcgg caagctgaga cgatcagcaa ctgcttgtgc tgtatctctt gctcgttgaa
    59761 gaggggaatg gatgattttc gtgattggaa caggcaaatc tactaccttt tctgctagtt
    59821 tctgtgcctg catctgtcct ttttcagtca gcggcacatc tgcccgtccg caaactaatc
    59881 cttgtgcgtt ccaagttgtt tctccgtgtc tcgttacata aagcatgtga ttctctcctt
    59941 cgttggcaaa gttcccctta accatacctt gttgttcttg agattacaag ggttagattc
    60001 tctcaagaga aataatctca gtagatactt tatccaggaa ggtttgatca tgttccacta
    60061 gtaacatggc aggtttcacg ttcaagatca gttgttctaa ttgttcttga ttgaagacat
    60121 ccaaataatt caatggttca tcccatgtat atagttcagc tggctgtgat aaagatttag
    60181 ccaattccac ttttttccgt tggcccatac tcatctgctc gatcttgtta tgaaaaacat
    60241 ctctttccat cccaagcttt cggaggttgt tcaaaaatgc ttggtagtct acttggtttt
    60301 tctctgcaaa ttccgccaac gttcctcgat tgtcttcata attttggctt gcataactaa
    60361 tgctcagatg ttttggctgg tatttttctc ctataacctt gccgttgaat gcccccagaa
    60421 gataatggat aatggatgac tttcctgcac cgttaggacc tgaaatcgcc acccgctgat
    60481 gaggctcgat tgtaaaatga attggctcga ataacagatt ttcataccct aattgaagat
    60541 cttctacgct taaaagtcgc ttatggtgag acgcttggct attcatcgtc aaagaatcga
    60601 tatattcgat atcttttaat agtttttctt tctcgctgat ctgggtctcc atccgattca
    60661 cgattgcttt ggatcgtttc atcgtccgtg cagcatcagc acccactgct cctttattca
    60721 ctcgtctaga ttcagtatcg atgaatccga cttgtttctt tgttttatct ccttctcggg
    60781 aacgagacca ttcggctttt tcagctgctg ttttctttag cctactgact tcttttttca
    60841 atttttcatt ttgagccatt tcaaattcat cacgaagttt tttctgttct tcatagatag
    60901 agaaattccc ttgataaagt tccagttgac ttttttcgat tgctaaaaca tggtccacta
    60961 cttcatcgat aaatccccgg tcatggctga ccacgatgaa gccttgtttt ttctttttca
    61021 aataagccgc tacttgtttt ctaccagaga tatccaaatg attcgttggt tcatcgatta
    61081 acgggaaatg agtgtcatcc acaaataaaa gtgccagtag gacttttgtc ttctctcccc
    61141 ccgatagtgt gctgaattct ctccataaga tttcaggatc tgtttgcatc aattggagct
    61201 ctctttcgat ttcccatatc tcaaaatccg taatatcatt taacacgtaa taggttaaac
    61261 gttctttatc ttttgtctgt tgcgggaaat aggcaaattc ttgctgatgg attacttgcc
    61321 cttgataagg tagtttgttt tgtagaatat tcagtaaagt tgtctttcct cgaccgtttc
    61381 gtccgataag tcctagtttc cattgtgtgt caaaatttag atttgcttgt tcaaataata
    61441 atgtgccttg gctgtcgtag ccgaatgtca gattttttat ttcgatttta gacattttcc
    61501 atcacctcgt aaaaaaagac cagtcctatt ttcagaactg gctaaagagg atgcaagggt
    61561 tggatacaca caaaaagacc catacatcga aaaaaccaag ccaatcccga aaatctgcac
    61621 actgcttcct tgtctccaca aggtacagtc tgaatgcagc tttcatcaat cgacttaatt
    61681 tttcaatgca cggatccctc actttgtcct atatttgaaa ttacgatagc ataaagaaaa
    61741 tgattttgtc aactacttcg ggaggatggt gaaaaatctg ctaagtgtct gtcctaagat
    61801 ttttgttttt tctaatgttt gcctgtgttc cattgcttct tctaaaccta ttggacccaa
    61861 atgaatactt aagacaattg ggagaaaatc agaaagtcct tctagctctt ggtctctact
    61921 tccgcaaata gcgattattg gttttcgata tttttttgca agcactgcta caccgtatgg
    61981 aacttttccg tggatcgttt gctgatcgat ccgcccttct cctgtaatga tgacatctgc
    62041 ttgttcgatc tttttttcca atccagtgat ttggctgact aaatcgaaac cagaaaccat
    62101 cttcgctccc aacaaaaaaa gggctccacc aataccgcct gctgctccac ttcctggaat
    62161 atcatctaaa tccacctccc agaaatcttt tatttgctga gcaatctttc ctgcttgttt
    62221 atctaagaaa gctagcgtcg tatctattcc tcctttttgt cttccaaatt gccaagcagc
    62281 tccttgttga cctgtatatg gattggtaac atctgcagcg ataatcaatt ttactttaga
    62341 aacaagaacg tttcttcgat caaaatgaag ttttttagta gataataaag gatttccttc
    62401 tgtgtaccct tctaaagaag cacccaagga ttggagtaat cctagaccac catcgctaca
    62461 cccgcttcct cctaaagtga caataatttg ttctacttct tgaagcagtg catctttaat
    62521 aagttctcct aaggcataac tggaagcaag tcggatagtt tgatccgttg gtttatcaag
    62581 tagatctaac cccaatgctt gtgcagattc gatgactgcg gtgttttttc cttgccaagt
    62641 tgtcaataaa tagctgattt ttcgctgacg gaataagaga tccatcccat caatggtacg
    62701 ccatgttccc ctgagcgcgt aatagattgc ttctgcagta ttttctccgc catctgcaat
    62761 cggcacattg atttttcttc ctttacgatc ttcccagcca tttagaactg cctgatttag
    62821 ttcaaatgaa gaagcacttc ctttaaatga atcaattgcc gccaaaatat ccatctgtat
    62881 ccctcacttt cttcttaagt aagacacttt ttttcatttt tttcaaacaa aacaatgcta
    62941 ttttcttcca tttttctata tactaaaagg gaactcattg aataaaggag agaaaaaaca
    63001 tgaaaatcgc aatagctggg gccggagcaa tgggcagccg aatcggattg atgctacatc
    63061 aaagcggaaa tgaggtcctc ttgatcgatc gttggcctgc tcacattgaa gccattcgta
    63121 caaatgggtt gattgctgac tttaacggta aagaagtggt cgcaaaactg ccaatctatt
    63181 caccagaaga aatcatcgaa agcaacgaac acgtggactt gatcgtagca ttaacaaaag
    63241 ccaatcaatt agatgatatg ttttgttcga tccaatccat tattactgac aatacttatg
    63301 ttttgtgttt actaaatgga ttaggtcatg aagatgtact ggaaaaatat gtgccaaaga
    63361 aaaatatctt atttgggatc acgatgtgga cagctggtct agctggtccc ggaaaagtca
    63421 cattgttagg tgatggagaa atcgaactag agaacttgga accagaaggc gaagcattta
    63481 caaaaaaagt tgtagaagtc tttcaagaag caaatttaaa tccgatctat agccataacg
    63541 ttcgttattc catttggcga aaagcttgtg taaatggaac attgaatggt ttatgcacga
    63601 ttttggattg taatattgct gaactaggcg cgcaaaaagc ggcagagagc atggttcgaa
    63661 caatcgtatc tgaatttgct tctatcgcag caaaagaagg aatcatacta gatcaagaag
    63721 aagtgtacca acatattgct tctacttatg atcctgacaa catcgggttg cattacccat
    63781 ctatgtacca agacctgatc aaaaaccatc gtttgactga aatcgactac atcaatggtg
    63841 ccatttggcg aaaaggacaa aaatatgata ttgctacacc atattgtgcc tttttgaccc
    63901 aattagtcca tgcaaaagaa ggaatccttg gcgcagaata aaaggctctc tgatgagaat
    63961 cagctgaatc agcagctggt tctctttttt taagcccaat aaaagatcaa aaagaaaaca
    64021 caactctcat gatgccataa gaattgtgct tgtttgtttc agtacataat ctcttcaaaa
    64081 tgtaggtttt ttatttgttt tcaacagagg agaggtcata ttcgtattgc tcataaatag
    64141 tggaatcgtt agtgataaat cgttttgccc aattttctgc atcataaaat tccaatagct
    64201 ctgataggat tggcttaaat ggtgtatgca gaaattccgg taattcatct aaatcacgtt
    64261 ctcgaagcaa aaaaatattt tcaggacgat aaaaatgata atgagcaatc gcttgattat
    64321 ccgtcactag tttcttttga aaatacatgg attcaaatgt ccgcaaagtc actccttgct
    64381 gaccctcccg caacagttcc agaatcccgc gcgattcccc tgtttttttc aggtactctt
    64441 cataagtaag atatccaggt tgttcattcc ctcgatgtgg aagaatgaaa tagttggtcg
    64501 taacatctct ttttataaat tcctgcttat agctttctgc tcgttctttt ctcccattat
    64561 tcgttgcacc aaaaaataga tccgtctttg gttcgctaga agaaaaattc atatgtttcg
    64621 aataaaatga actattatgt ttcagcccaa gttcttttgc ttccaaaaaa tcaaaatgat
    64681 aaatctcatc gattgccggt tcatcttgtg cctgcttcag catcgcctcg tgttctgctt
    64741 tgaagtgatt ccaaaaaaat aacacaattt ttgcattggt aaatgggcgc acgcgtcgag
    64801 ccatctccat atcaaatcca taatctaaaa aaacgatcag ctgataattt gccaactgtt
    64861 gtctagctga tttaatgaat tccgactgta gtaaatcttt tccggaccaa acatctaaag
    64921 agcggatgga aggcaaaaaa taaagtgatt tattttttgc aactagcagt acgtcatttt
    64981 tgttcatctt ttccgcctca ctttctctgt cactttttcc tatgatagcc tgtttaaata
    65041 gtaaaaagcc agtaaaacgt ttcctatatt tgtatgaaaa tttaacattt gtatgaaaat
    65101 atgatgaaat aaatcattct tctattaaaa ttcgcctaaa agttttctga atagttgtaa
    65161 ttgtctgaaa atttgttatc attagtcatt gttaaatatt gctatttatt cttaatataa
    65221 attttgattg tgaatttaaa agaaagaggt catttatgga agataaaaaa ttgaaaaaac
    65281 aacttagctc cagacatatc accatgttag ctttaggtgg agcaatcggt gcaggtctat
    65341 ttaaaggaag tggcgaagcg attgggatcg ccggcccttc tgtattgatt gcttttttga
    65401 ttggtgggct gattttatat atcgtgatga aaggtctggg aaaaatcgtt ttaagcggtg
    65461 gcgacacgca tcacggatta tctggtttga tacgccctta tctaggtgct cattctgctg
    65521 attttactga ttgggtctac tggtctatgt ggattatcaa tatcatcgct gaagctgttg
    65581 cagctgcttc ctttttgcag ttgtggttcc cgcacattcc agcctgggta tttgttttta
    65641 tgttggctgt tttaactacg atcatcaatc tttattcggt acggttattc gcagaaacag
    65701 aatattggct ggcttttgct aaaatcagtg tcattatctt actgatcatt tttgctactt
    65761 atcttgtcgg tcagcaaatg ttgggcacag gcgttttccc tacccttcag caattgactg
    65821 accatggtgg gtttactcct catggtatga agggaatcat cagttctttg cttgtagtta
    65881 tctattctta cggcggttct gaactgattg ctatcacggt aagcgaagca gatgatccta
    65941 aacgtgcgat tcctaaagca atcaaaggtg tcatgggaag aatcatttcc ttttacatca
    66001 ttcctttgtt tttgcttttg attctttttc cttggaatac tttagcaggc acgaatgtca
    66061 gtccttttgt gatggtattt gaaaaaatga atatcccatt tgcagcggat atcgtcaatt
    66121 ttgtgattgt ccttgctttg ttctcatcta tcaattcggg tgtgtatgca tcttcaagaa
    66181 ttttgttctt ccgtttgaag gatcgaaaag gttcctctag aaaactagct gttttaaaca
    66241 agcatcaagt accgcaacgt gctgttttat tttgtaccag tgttctttat cttggtgtag
    66301 ctctttctta ttttgtcggt gacaaattat ttggctatct ggcaggttcc ctttcgtata
    66361 cagtattatt gatctggatc attatcagtg cggcatcctt tgtactggca ctaagaaaag
    66421 gaacattatg ggataaagga atcagctttt ttgcattagc tgtcttagga ttgattttcc
    66481 ttggtatcct gttcacgaac tccattgggg taactgtatt gactggcctg ctttacctgt
    66541 tcatttattt cagttatcaa aaaaagaatg atgcgttcgt attgacgaat gaatgaaatc
    66601 gatagaaaat tttattttat ttatgtggaa tagatggagc tattgaagaa aggagttgtg
    66661 acaaaagtct tgttgcaact cctttttccg aataaacagt ctcatgacct cttggtaaac
    66721 ggtgttcaaa aaccctctgt gcaaaataat tgattgttct ccatgctcat gacatgatag
    66781 aagaaaggaa tgaaaaaaag gagtttgttt taaatgaaaa agtattggaa gtttttgttg
    66841 atgatcggtg tttcaacggt agttatgttt ggtatgatgt acttgaatgt ctatgcgctc
    66901 gatcatatct tcttcagtcg tacacgagta ttcatggcgt tgatgatggg tgcagtcatg
    66961 gcagtcatca tgctgttgtt catgtggaaa atgtatgaaa acaaaaagat aaatgttatg
    67021 atcttagccg ctagtcttct tgtttttgcc ggttccttgt ttatggtacg aagccaaact
    67081 actgtcaacg acacagcttg gatgaaggcc atgattcctc atcattctat cgctatcctg
    67141 gcaagtaaac gagctgattt aaaagatcct gaagtaaaaa aattagcgga agaaatcatt
    67201 caggcacaag aagaagagat cgacaaaatg aaaaaaatga tcaaagaaat ggaatgacca
    67261 ttatccgtcc aaataaaaaa agaggatgtt ccagaagtta tcagcttcaa gaaataagaa
    67321 gaagctactt ctggaacgcc gtgaataagg ggttgtgaaa aagctgccct gcatcaagta
    67381 ataagaacag ccaaacaaaa atagcttctc ctatttttcg tttggttagg cttattaccg
    67441 cagatgcaag cttttgaaca ccgtttatta agaggttgta aaatcagcgt tctgacctga
    67501 gtattagaga gacaaatgga aaaatagttc ctcatatttt gccatttttt gagctaatac
    67561 cgagggtcag ctgattgaac accgtttatc gagaggttgt gaaaaagtcg cttagtttcg
    67621 cgtattaaga aaaattttgt gaaatggctt tccacatttt tgtataaatt tggcttaata
    67681 ccgagaaact ggcttttgaa taccgtttat tcgtaaaagg gattgtgaca aaagtcttgt
    67741 cacaatccct ttttatgttt ttattgttct aattgcgctg tcttgcttac tgcttcttgc
    67801 ggtttcacaa atttttttga gattccccaa cctgtgaagg cactgaccat cgaaaacaca
    67861 ggagaaagca aactgaaaaa tacgaatggc aagtaagtga gtgtaggaat accaaatgta
    67921 cttgctacga aacttccggc aattccccaa ggcactaagt agttgattac tgttccacca
    67981 tcttctagcg ttctacctaa tacagttgga tcaaatcctg ctttttcata agtttcttta
    68041 aatgcattac caggcagaat aacagatagg aattgttcac caataaaaat atttactccg
    68101 atacttgtca tcaatgttgt aaaaatcaaa tttggtgtgt tcgtcatctt tcttgatact
    68161 cgttccatca cggttgagat caagccaaat tcgatcaaca atccacctaa tgacaaagtt
    68221 agaataatca atgacacagt aggcatcata ctttcgattc ctccgcggct aagcagtgaa
    68281 tcgatttgtt ggtttccagt atttgaaaca aaccctgatt cgatgacccc agccaacttc
    68341 gttaaggaag tttgtgggtt ttgaataaaa atcattccta ctgctacagc gatattcaac
    68401 aaaatcgtta aaattgccgg cacctttttc catgcacaca gtaacattaa aaataaagga
    68461 atcagtgacc agattgaaat agtaaagttt gcttctagaa catcagtcac ttcacgaata
    68521 gatgaaagac ttgcggcttt acttgtgtgt cctaaaatca tgaataaaaa gaaagaaaca
    68581 acaaatgccg ggacagttga ccacatcata tgcttgatgt gtttgaacaa atcggcatca
    68641 acaatagctg ctgctagatt tgttgattcg gataatggag acatcttatc tccaaaaacg
    68701 gcacctgaaa caatagctcc aacaaccagc gctggattta agcctagtgt tgtcccaata
    68761 ccgaaaaatg caatcccaat cgttgacata acagtaaagg cactccctac agcgctacct
    68821 acgattgcac acacaacaaa tacagaaggg acaaaccact ggacactgat caatttgaac
    68881 ccaatgacca ttagagttgg aatgatccct gcttgtatcc atacagcaat caatgaaccg
    68941 actaaaataa aaataaagat tgggatgatt cctggtttga tgccattgat gattccttcg
    69001 tgcagccaat ctgtcgggta tctttttatc actgcataca acatgaccat tccgatcgct
    69061 gctaagatcg tgatattagg tgagaccttt aatccgacaa cgccaatcgc aatgcctaaa
    69121 acaataacca ttaatacaag tgttgcttct aaaaaacttg gtgttccttt ttttcccatg
    69181 ataatctctc cttttttagt tgttcttatg ttctaaaaaa gttaagatat cggattactc
    69241 cgccgcaatt catccgcgat tcctccttta taaaaataaa aagacctgtt ttaaactaag
    69301 gacgaatgac tccgcggtac caccttaatt aaaaacagat ctgtttttca ctttcaaact
    69361 tttattcaaa tgtatggact ttccatgtaa ttcgtcaatt aggcttgatc ggttcacagc
    69421 gaccaccgac tttctgaaca aaacacctaa ccgctactgc gtgaaaagtt gacttgtacg
    69481 aagtttacct tccataagat catttgtcaa tgaaaaagaa aatatttttt catttttctg
    69541 aaaattattt ttataacttt cacacacaag tttatttttt actagaaagt agcgccctct
    69601 tgtttttttc ttgctactat ttcttgatgt tcttgcttga ttctttctaa tagctttggc
    69661 tctttcaaca gatcaagagc tgtattggcg agtagttctg ctgcaatcgc aatagaagca
    69721 aggcctttgt cacttttagc agcagctttg aattcttctg tgtgtccggc aatatatgtc
    69781 tcagagattg ctaccgtagg ctggattgtt ggtatgactt ggctgacatt tcctacatca
    69841 gaagaaccga gacttgttct ttgttccgtt tctatttctt catctggaac acctgcttct
    69901 tttgcatgct ggaagaataa gtcatcaaaa gaaggagtaa cgatgacatc atcaactgca
    69961 ttttggaaca atccaaactc aaaagtcgtg cccgtactta tcgcagcacc tcgtacgata
    70021 ttttccactt tttcatatac tttatctaat gtttgccgat ttcctgcacg taaatagaaa
    70081 cgtccagcag cgtaatctgg aatgacgttg gcagctactc ctccgtctgt aatgatccca
    70141 tggatattga catcttttgg caattgcaag cgtagagcgt tgattccatt aaacacttgg
    70201 atcaatgctt ccaaagcatt tactcctttt tcaggtgctg ctgctgcatg ggaagcgaca
    70261 ccgtaaaatt tgatgtcgac tggatcattc gctaaagatt ctgtcgtttt cccataacga
    70321 aaagctggat ggacgcataa cgctacatcg acatcctcaa aaaaaccttc tcgaacaaag
    70381 ctgcctttag ctgatccgtt ctcgccccct tcttcccctg gggtgccata tacacggatt
    70441 tctccaccag tttcatcaat gaattgcttc actatgctgg cggctaatac ggagtaagta
    70501 ccaaacaaat tatgcccgca tgcatgacca atacctggta aagcatcgaa ttctgccaaa
    70561 aaggcaattg tgggaccggg tttattggaa atataacgtg catcaaaggc tgttcggtgt
    70621 ccagctactt ctttttctac ccaaaacctt tctttttcta attgtttaat caacgctgct
    70681 gaggaataaa actcatagtt acttacttca ggatgttcgt ggatatctag agcaagtgct
    70741 tgatattctg gtaaacgata ttggattaga tccttcaatt ggtttgttga gattgttgtt
    70801 gtcataaaaa attcctccta tgctagtcat ttttcttatt ttctcccgaa tgtttcccat
    70861 gcaggcacgc ttgatccttt tgatgttttc tcgattactt tgactgtgtc ttctgtttga
    70921 taagcgtcta ctattttttg atacgtttta ttgttttcat cttcttttct tgcaacgatg
    70981 atattcacat aaggacgtgc atggtcatcc actggttcta agaagatggc atcagaagca
    71041 ggattaaatc cagcatctac agctacaccg ctattgatca ctgaaatgtc tacatctgac
    71101 aaagcacgtg ctgtttggga agcatctaat tcagaaatgt ctagattttt tctattctcg
    71161 gtaatatcag aaacagtggg cgcttgtcct tttgccttat ccactttgat caatccagca
    71221 gtttgcaata acagaagagc tctgccgcca tttgtaacat cattagggat tgctactttt
    71281 gctccgtctt tgatatcagc tacatccttc aaagtgttag aataaattcc cagcggtgca
    71341 ttgacagtat ttccgatcga tactaaatca gttccgtgtt ctttattgta attgtctaaa
    71401 aagaattgat gttggaaaga attcaaatca atcgatccat ctgctaaagc cacatttggt
    71461 tgattgtaat ctgtaaattt cacgtattcc aaattaatgt tctccttttt caaacggtct
    71521 ttcacgttgt cccatacatc tgtatcttct ccaataatcc ctagttttac gatagtttct
    71581 tttttgtcag ttgtatctgc ttttccttgg ctacaccctg ccaaccaaat aattgctaca
    71641 aatgtaatga ctacaaaacg aataattttt ttcatttttt ctcctccact ttcaatgtgt
    71701 aattttttta atcagttgat tactgataaa ttgacttaaa aaaactaaga ttagaatcaa
    71761 taatgtagcc acaatcgtta catctgtttg gaatcgatta taccctctcg atatagcaag
    71821 attccctaat ccgcctgcac ctactgctcc agccatggta gtcagtccga tcacgttgat
    71881 gatagtcaac gccgagaccc gaatgatacc aggcaaacct tctaacaaat acacacgtaa
    71941 aatgataccg attggactgg ttcccatcgc ttctgccgct tcgatcaccc caggatcaac
    72001 ttctagcagt gcgttctcga tttgacgagc aaaaaacgga acaactccaa aaatcaatgg
    72061 cactaaagct gctttcgcac caatcgtcgt tccaactaag aaacgagtag tcaatgctaa
    72121 aagagaaagc aagataatga aagggatgga acgaatgata ttgatcagct tatcaagtat
    72181 ttcaaatagc agacggttag ctagtaatcc attagggcgt gtcactacta acgtcacacc
    72241 taagatgatt ccaatcatcc cgccaatgaa tgctgtccaa aaagacatat atagtgtttg
    72301 cttcgtcgct tcgacaaatt catccggaat caaataaaca ttgggcaaat atgttttaaa
    72361 gaaatcagtc attttatctt cctccttcga tcactttgat acgactatct aaatcgtttt
    72421 tttgtaaaat atttattttt acaccagatt tgatcaaata atccaatgct tttttccgct
    72481 gtttggtttc tccagctaaa gtaacgatca aactccctaa cggcgtttct tgtaataact
    72541 ctacattgcc atataaaata ttcgctgtta cttgatattt gctgtacaga tgagcgatta
    72601 gaggttcgtt cgtctgattt ccaatataac ttaattccac cagccattta ttggcgatct
    72661 gatcggcaaa agcagaatgg gcaatgatcg tttctaatgc ttggtcaaga tgagtagctg
    72721 ttcgaataaa atctttggtc aattcttctt caggattgct gaagatctgg atgctgctac
    72781 ctttttcaac gattcttcca tcttccataa ccgctacctt gttgcagatt tctttgacaa
    72841 cttgcatctc atgagtgatc aggacgattg ttaaacctaa ctggcgattc aattttttta
    72901 acaatgcaag gatctgaagg gtcgttttcg gatcaagtgc actggttgct tcatcacata
    72961 ataatacctt aggttcattc gccaaagctc gtgcgattgc tactcgttgt ttttgtcccc
    73021 ccgacagttg tttaggataa gcagatgctt tttcttccaa accgacaagt tccagtagtt
    73081 cattcacttt ttgacgacgt tcctgtttcg attttccaga atactttaaa gaaaaatcaa
    73141 cgttgtcaaa aatagttcgg ctttccatta gattgaaatg ctgaaagatc ataccgatgg
    73201 cctttctttc ttttcgcaat tctttgggag agagctgact cagattcgtc tgattgacaa
    73261 tgacttctcc tgctgttggt ttctgcagca aattcatcac acgaactaac gtacttttcc
    73321 ctgcacctga gtaaccgacg attccataaa catcgccttt ttcaatcgtt aaatctacag
    73381 aatctactgc ctgtatctct ttttcttttt gtttgaaaca tacagaaaca tctcgcaatt
    73441 caatcattaa aattcctcct tatctaaaaa aagcgtcctc aagaaaatga aaatgtcatt
    73501 ttcttgagga cgcttttttg cgtgttacca cctcatgttc aagctgtgtt cacacacaac
    73561 tcctcttcaa gtacgatcat actctagcaa gatatcggtc gcagccgtca tcgccttaca
    73621 tctatgctcg ggatgaattg ctcgatggcc attttccaat agtcgttcct tgcttcttct
    73681 cagctaccga agctctctgt caaaggttct tctatcgtac ttaccatttc aatgcaaata
    73741 atattcaaaa aaaaagtcct tttactaaca taaactatgt cagtaaaagg acgacgtatc
    73801 gcggtaccac cttttttcgg aagtttcctt ccctcaagcc caacatctca aaaagagaga
    73861 ttggcgttcg ttttaacggt cgaacagttc cgaatttgcc tacttatcga caaattattc
    73921 tccaaggcca ttttcagctt ttcttacttg actcttctca ccagccagag cctctctgca
    73981 aagtttccaa acttactttc cttttcaacg aaatcgatat tttgttgttg ggattaatct
    74041 acatgaggaa aactgaaaag tcaagtacga aattcaaatt attttttcta tatttatttt
    74101 tctgtttttt tatttaacat ttcaataaca gttcgaagat cttttccttc cgcaagaagt
    74161 ttcaattttt ccttttcttc gacggtataa tttcggacaa aactggaatc aggtatcaaa
    74221 acaacgccta atcctgctcg tgaagcagct gttgctccta ctaaagaatc ttccactgca
    74281 aaggctgaac tagcttctaa tcctgttcgt tccaaagctg tcagataagg aatcggtgaa
    74341 ggcttgttct ccgacacttc gtctccgaat gtaaacgtgt ccaagtaatc agctaattta
    74401 aagtgatcca agatatctgt tgctcttttc gtaacagtgg tcgtagcaat gcctagtttc
    74461 atatgacgtt cttttaagtc tgccaatatt tcttttgcat atggttttaa gtggatggct
    74521 ccgcttgtca gctgttgata aaaatattct tcacgcttcg ctcggacttc ctgtactttt
    74581 tcagggctac ctgctgcttt cactaaaata tcaaaacttt gtttccagtt ttttccgccc
    74641 caagcgtcaa cgatttcttt tgggatatgg atatcaaatt gctgaaatcc ccaaagccag
    74701 ccatcacgat acgttttttc tgtgtcaact aacaaaccat ctaaatcaaa tattgcacct
    74761 ttcatctata cattaatcct ttccaaaaca atacacatag tttagcacga ctggtccaaa
    74821 aagaacagaa gcaaagaacc agccttctcg tttataagag ttcttggaat cgacggatat
    74881 agattttctt cacagctgtc acaagcgcca gataagcgat gactgtagca aataaccata
    74941 accagtaatt gccaggaagt ggcatcaagc ctaattcagc accaaaactt gtaaaaggaa
    75001 ggacagaacc gacaataatt cctaatgtag tgataacaaa catggcaaat gttgcgttgc
    75061 tttggataaa tggtactttc ggtgtacgca gtgcatggag cactaaggtt tgtgtccata
    75121 gtgattcgac aaaccatcct gcatggaata atgcgatgaa aatcactcgc tgtgaactat
    75181 ccaatgtatg gaaacttccg cccactacag caggacaaat aacaaaatac atcaacaagt
    75241 aagtagtaat atcaaatatc gaacttgttg gaccaaagta aaccatgaat tccccaatac
    75301 tagatgcatt ccattttttt ggctcgtcca aatattcttt atccatccga tcccatggca
    75361 aggaaatgca ggaaacatca tagatcagat tcaaaaacaa aagttgtaaa ggcagcattg
    75421 gtaaaaatgg caggaacgta cttgcaatca gcacggaaaa catattgcca aaattagaac
    75481 ttgctgtagc cttgatatat ttcatgatat tcccaaaagt ttctcgtcca gaaagaaggc
    75541 ctctttccaa aatcgtcaaa tctttttcta aaaggatcac gtctgcagat tctttcgcaa
    75601 tatccacagc tgtatctaca gaaataccga tatcagccac tttcattgca ggagcgtcat
    75661 tgataccatc tcctaaaaat ccgacagtat gaccattttt acgtaaagct gtcgtcaaac
    75721 gtgctttttg ctgaggattc aattttacga atacttcatg gtcttcagct acttgtgcta
    75781 attcatgatc actcatttcc gagattttct caccggtaac caattcattg atctctagac
    75841 ctacttgacg gcacactgaa cgtgtaacta attcgttgtc cccagtcaga acttttacag
    75901 ctacaccatg ttctttcaga gctttcaacg cttgtttcgt tgtttctttt ggtggatcaa
    75961 ggaaagcaag ataaccaatc aaaaccatgt ctgactcatc tttgactgaa aattctccaa
    76021 cgacgcttgg attggtcttt tgtgcgacac caatcactcg taagccatct tcattaagtg
    76081 actgtacttt tgcaagtacg gcttcttttc gttcttttgt taatggtgta acagtaccgc
    76141 caagatcaat aaatttagaa atgttcagca tttcttcaat cgcgcctttt gtgatcattt
    76201 gtgttttacc agctggatca gcaaccacaa cactcatacg acgacgttca aaatcaaaag
    76261 gaatttcatc cactttttga taattgatct tatctgtatc taaagtttct gttgcttcat
    76321 caatgatagc cacatctaac aaatttttca gccctgtttg atagtagcta tttagatacg
    76381 catggcgcaa aacacgatca tcttcatttc cttcacaatc catatgatat tcaagaatga
    76441 ttttatcttg tgtcaatgtc cccgttttat ccgtacataa cacatcgatt gcaccaaagt
    76501 tctggatggc attcaaattt ttgatcactg ttcctttttt ggccatcaca cttgctcctt
    76561 tgaccaaatt cgtcgtaacg atcattggaa gcatttcagg tgttagacca actgctacag
    76621 atagtccaaa aagaaaagct tctagccaat ccccttttgt aagcccattg atgacgataa
    76681 ctgctggagc catcaatgac ataaatttga tcagtagcat ggatgtttta tggatgccta
    76741 attcaaagct tgattgaatt ggtttttcag atagcgtttc tgctacatga ccaaatagtg
    76801 tttcatttcc aacagaaaca atgattcctt ccgcacttcc actgatgaca ttacttccca
    76861 taaagacaag attttcgtaa cttgtttcgc tttgctgatc gtcttcacat actttcgcat
    76921 gcttttctac tggatagctt tcccctgtca atgctgcttg ggaaatgaat aaatcctttg
    76981 cggacaataa acgcatatcc gctggtatca tatcccctgc tgaaagccga acaagatctc
    77041 cacagacgat ttcttccata ggaatctctg tgtactttcc attacgtttt acagctgccg
    77101 ttactttcac aagtgatttc agtttttcag ccgcttgatt ggaacgtacg gactgaatca
    77161 acgtcattgt cccgctgacg ataaccatag tgaagataat ggctacaccg aaaagatctt
    77221 tatctccagg agctgctaat acatattccg tgatgaatga aataattcct aatgcgatca
    77281 acactaatgt aaatggcgtg atgtatgctt tcaatatttc tacaatgaat ggtgtttttt
    77341 tgccatatga aatcgcattt tcaccgtaat tttctcttga acgttcgatt tgttcttctg
    77401 tcaatccatt tgctgatgca tggaatagtt caaataattc ttgtttcgtt tttccagcaa
    77461 aagctgcata gattttttgt gtatctttct ttttttccat ctcaatctct cctttgtgtc
    77521 caaaagacag ctgttctcgc tgcttttggt ctttagctat tcatcggatc gatagagaaa
    77581 aaactgaaag gggctgagaa cagatagata atagccctgg cctttcctct agatccttgt
    77641 ttttcgaatg actgtcatcc atttgttctc atctccttta ctaagtaatt ttaattcatg
    77701 acttccaatc atttttcgaa tagttatttt tccaattaga ccacctcctt tttatttttc
    77761 accgatgggg atttgcggca acaaaaaaac ctctcgccaa atactcagcg aaaggtttga
    77821 aaaagcatat taaaaaaagc ttctcagatc tcatcgttga gttttgacac tgtacaacgt
    77881 aaaaagcaga tacctgcttt tagctacctt atgaaaagcc ttatctcgac aattcctgtt
    77941 ctacccattg gcgtctctcg acgtttttgg gcagtagcct atgtttgtat aggagcctca
    78001 cctaacaaat cttattcggt tttccttcgt taatataaca actaaaaaag aggatgtcaa
    78061 atcaattttc catgtttttc atactttttt taaaatacac acgttatatt cctgtctcac
    78121 gcggttttat ttgtctcatt ttccacctcc cgctataata gaaatatagt aggaaacgag
    78181 gtgctgttat ggaaagaaca cttgttatta tcaagccaga cggcgtgaga cgccatttag
    78241 tcggaagcat catccaacgt tttgaagcaa agggactggc cattgctgaa atgaagtttg
    78301 aaactatgac tcctgaatta gcaaaagaac attatcagca cttgactgag cgcagttttt
    78361 ttgatgaact gatcgattac atgacttccg gtcctgtcgt ttatcttgtg ctggtcggcg
    78421 aggaagtgat cgatatcgtc cgtaagatgg ttggagcaac aaaagctgcc gatgctgttc
    78481 caggtacgat ccgaggagac tacgcgctgc cggggactga aaacatcatt cacgcttctg
    78541 attcccgtga tgctgcggta aaagagatcg cccgcttttt cccgccattc gatataaaca
    78601 aaccgtctga aaaagcggcg aagtgataca aattctaaac tgctggtcta gttgctgggt
    78661 tcagcaatgg ccagcagttt tttctctaag gacctccgtt gattctttcc taacatatat
    78721 tcgagcactg tgaagaattc ttggtagtct ttcgtctttt cttcccctaa agcagcagaa
    78781 atcaatcttt gataataatc tgccatcaat gtttcataga tcactgtact tctttcttta
    78841 tgtgataagc tccgtttcat atcttcattc acactacgtg cctttttcaa ccgaccattt
    78901 tctatataaa acgaagtcag gttcattaaa aaagtaaaga gatactgctc atgattgttc
    78961 aactgtgcta atcgtcgcat tctttttttg attttcaaat aattgttctc aatgaaccga
    79021 tcactgaata tccaaggaaa atcagctaga atagatagtt caaattgacc atagtctggt
    79081 atctgcatca agtattcttc aatgattcgg cattcataac gtaaaaattc aaattctgtc
    79141 tcagatactt ctgttttttc gaccatgtga agattcaaaa ccaaataata cagatcttct
    79201 gttttcttaa aatgcctacg gttattgctg atctctttat aaggatcaaa gctgtcttct
    79261 tgtacccgat ctagcattcg tctttttttc tttaacttta ttggttcatc cagctggttt
    79321 cgcatccatt catattctgc aagtgtcatg ttcattcgct ctaaaaatga tctcaatgtt
    79381 acaaatgaca tttttttcac tgaatttgtc tcaatcccga ctagagaagt cttaaaacag
    79441 attccttccg ctaattggga ctgtgtcaac ttcttgttga ctcgaagttt cttgatcaat
    79501 tcaccatcat acataatagt tctccttttt aatttaaatt tttccacatt caataaatag
    79561 atacgttaaa aaggaaaaat acacgaaaaa aataaaaaaa tgtttttttc ataaaaaata
    79621 ccaaccttca agcattagaa tgttgtctaa ctactgaagg ttggtttgat tgtttattga
    79681 ttattttttt gctgttcaac gtctgttctt gttactggat ataagttggt tgttgtttta
    79741 ttaccatttt ttgaaaagac acttgtcgaa tgttcgcctt tttgcttttc gattgcttca
    79801 ttacgttccg cttcattttt atagtcatat tttttcggat caatcgtctc aaatccgttt
    79861 ggcacataaa accgcaagag attttcctga ttcagcttat ctgaaagact taacgcagtc
    79921 ttgacttttt cctgatcttt ggagatttcc tcatcgattc ctgctgcttt cgtatcgatg
    79981 atttctcctg tctgattatt gtaagctttt cctcctagga cggtgtattt gggtgtcaca
    80041 aagttcccat ttcgaaaagc aactacttga tcatgctgag aagataataa gtctgtacca
    80101 aaatgaagat aatctttatc atcgattccc aatagatgta gtaatgtcgg caaaacatcg
    80161 atttctccac cgtattcatg attgactgtc cctttagtat aaccaggcat atggatcatc
    80221 aatggcactc gttgcatctg tgcgttgtca aattcatccc atgtatctgg atctttacca
    80281 agagcgcttg ctaaatcttt attatctgta ttcgagatcc caaaatgatc cccgtaaatc
    80341 acaaagattg aattttggta aataccagat tttttcaaat acgtaaaaaa ttgttccaat
    80401 gattgatcca gataatgtgc cgttcgaaca taattatcta ctgtgctatt gccagtattc
    80461 aaagatggaa agtcgaaatt cttgtcatcc gtataataag gcgtgtggtt ggttacggaa
    80521 agaaatttcg tgtaaaacgg ctgttgtaga tgctcaagat attgggcaga ttctctgaat
    80581 aaatctttat ctaatatccc ataacctaac gtttcgtcgg attcatcaaa ataagatcga
    80641 tcaaagaaat tgtcataacc taagttttta tatacatgat ctctattcca aaaactagct
    80701 acattcccat ggaaaacagc gcttgtatag ccttgctttt gtccaaggat cgctggtgcg
    80761 gcttgaaaga cattgtctga cccaagttct gtgaataatg agccttgagg taaaccaaat
    80821 gtgccagttt ccaacatatt ttcagcatca cttgtctttc cctgtcctac ttcatgaaag
    80881 aaattgtcaa agctgatcgt tgcttgattc tggaaaatac tatttaaaaa cggtgtgact
    80941 tcttgtccgt ctaccttcat attaatcaaa aactgctgga aactttctaa atggagaacg
    81001 atcacatttt tccctttagc gatcccaaat gtttcgggat ttggctctgc ataatgtttc
    81061 tttgtataat ctaaaacttc atcaatccca ttactgcttg catgcgcgcg aacactgcta
    81121 gtcattcctg ttttgattcc gtcataaata gtatacgcat cgattcctag atatttgaca
    81181 atatatgaac ggtcaaatgt tcgctgcagc aattgtggac ggttggcttc gctcagcgct
    81241 agatttcctg aaaaaataag ccctgaaaga caggtaacag cgatagccat cggtttgccg
    81301 acagggttgc ttttgatagg tattttcttg accttcaacc aaaccagtag cccaatgaac
    81361 acagcgatat ccagccagta gatgacatca tggggcttca tcaaagaaaa ggagcttcct
    81421 gacaatcctt gcgacacttt cgaaaagcct aatacagatt tgactgtaat gaaatctgtg
    81481 aattcccgat aaaaaataat attcaagtac aacaaaagcg tatttaaaat atcaatgatc
    81541 aaaagaatag ctaacgctgg ctttggcttt ttaatataca aagaaaggcc aaaaaacaat
    81601 aaggtagtcg caattgggtt gatccacaag ataaagtact ggatcgtacc ttccacacct
    81661 aatgaaaaat ctgcatagta ggcaatgatc gtcttcagcc agaaaaagaa aacagctgtc
    81721 aaaacgattg ctaaacgatt ttggcacaat tttttaagtt gtgtcacgta tatcacttct
    81781 ctctattcac attttttctt attttgctcc tgaaaaatga aaatttccta aaaaagttgt
    81841 tatcttaaga tttttttatt ctttctaaag attattccgt ccacttttca cagcataaaa
    81901 ccgctgcgat gtaagcgatt aaactaatga agagataaaa gtcttgtggt gaccgcttca
    81961 ctccacggta ttcaaaagcc agtttctcgg tattcgtaca aaaaaagagg ctgtgacaaa
    82021 attcttgtcg cagctcctta tttcttgatg caggacagct ttttcacaac ttcttcctta
    82081 aacggtgttc tcctgccaac tcctcggcca caagtcacaa tatttataaa acatgagaag
    82141 ctgttttttg aaattgttcc ttgtggctca gagttaaacg gcaggctcaa gacctcttga
    82201 tacacggtgt tcaatcagct gaccctcggt attagattat gtcaggacgc taattttaca
    82261 acctcttggt aaacggtgtt caaaagcttg catctgcggt aataagccca accaaacgaa
    82321 aaatataagg agctattttt tgaaattgct ccttgtggct cagagttaaa cggcaggctc
    82381 aagacctctt gatacacggt gttcaatcag ctgaccttcg gtattagctc aaaaaacggc
    82441 aaaatatgag gaactatttt gccgtttgtt tctctaatac tcaggtcaaa acgctgattt
    82501 cacaacctct gtttttcatt gtccatagga ttgatattgt ccttgtgatg actcattcgt
    82561 aataattgag gcttgatttt cttcacttcc cgttatcgtt tgtccactgc cagaatctga
    82621 aggacttgtt cctgtcgact cgtttttttg agaagagaca gttgttttct tgacttgttc
    82681 atttgtcttt ttccattccg ctaaacgatc ggcgaccact tttttgtcta ctttttcaga
    82741 ataagcggtg atcacttttc catttttcaa acgggctact ttgtcgccat catgagtcaa
    82801 aagcaaaacg gtcaaatgct tgtctttaaa ttgatattgt ctgagagaaa tcgcactaag
    82861 tacgtcatcg atattaataa attgattttc ttcttttcct tttggcaaat aaatgtccaa
    82921 ttcgcctttt tcgtaattgg cagttatttt atactccgcc caccaataag ttgagaattc
    82981 ttttttgaaa ttatctactg attctttgct tgctacgatt ttttctgttt ctttctgagc
    83041 aagatctgct gtcatttttc ctgaaaatgc tgcggataaa ataagcagta agaaaaaacc
    83101 gaataaccaa aagagaagaa acggtctttt tttcctcatg ctttcctcca ctcctattta
    83161 attttgacta ttctattata tacaaaaaat gaaatagaaa gacaaaaaag ttgaaaaaga
    83221 tcgtaaataa ttgaacttct ttttcacaaa atggtaagaa tggagaattt cacgcatttg
    83281 ctctcaacta ttctttctta agcctcaaat ccgtttttat ctgatacgtc tttgaaccaa
    83341 tgacccgatt ttttgattgt tctttttcca tcttgtgcta agtctactga aataaagcca
    83401 tatcgattct tatatgcatt ggtccacgac cagttatcca tacatgtcca catatgatag
    83461 cctaaacaat tggcaccttc ttgaatggct tgatggacat atttcagatg agattggaca
    83521 aattcgatcc gataatcatc gtggatcatg ccatcttctt tgataaatcg tgcttcgttt
    83581 tctacaccca taccgttttc agaaataaag cagtcgatat ttccataatg atctcgtaca
    83641 ttgatcaaaa tatcatagat tccttgttca tagatctccc atccgcgata aggattcatt
    83701 ttacgaccag gcatttcata attgtcgaaa taatcctcag gcattggacc gtttttagta
    83761 tcgattggtg tttcttttgc ttttacccgg cgtggctggt aataattgat acctaaaaga
    83821 tctactgtat tttctttgat aaccgtcaaa tcctctgcat ggatcacagg catgagatca
    83881 agttctttta ctatctcaat caattcactt ggaaactcgc cttttacagc tggatcaagg
    83941 aatgaacgat tgaagaacgc atctgctatt tgcgctgctt taacatcttc agggtttgat
    84001 tcgtctcttg gatagcttgg tgtcagattc aagatgatac caataacacc accttgctcc
    84061 atttcatggt aagatttgat ggctaacgct gaagccaacg cttcatgata gccaacttgg
    84121 atcgcttttt tcatatctga ctcttctgga taatgccatc gatataaata acctgcttcg
    84181 actggaacga ttggttcatt atgagtaaac cattttttta ctttcgaacc aaacaattca
    84241 aaacaacttt tggcatattt ttcataggct tcaaccgttt ctcggttcaa ccatccgcct
    84301 ttttcttgca gatacatcgg catatcgaaa tgatacagat tcacaaaggg ttcgataccg
    84361 ttttcaatca actcatcaaa ataacgatga tagaaacgaa cggcttcttc gttgattgtt
    84421 ccagattcat caggtatcaa acggctccat tggatagatg ttcgaaatga attatgccca
    84481 gtctgtttca tcaactgtac atcctcttga tacttcgtat aaacttgcga ggttttttca
    84541 ggtcctactt gatcaaagaa cttttgcggt tcttttttgt accaataatc aaaaatgttc
    84601 tctccttttc catcgcctga aatccttcct tctgtttgtg ggccacttgc tgcagaaccc
    84661 caccaaaaat ttgctggaaa ttgatatttt ttcatcaaag cacctctttt tcttttttag
    84721 ttcgttttag ttgattccat gtatgatatt ttccatcaca atcacttttt cattttcttc
    84781 ctcttctttt ttgattcgtt ttaacagctg ttctgctgct cgttccccga ttttatctgt
    84841 tggtggcgtg atcgtgattt tcggaaggat actcagatcg tttttatcta aataatcata
    84901 gtgactgaac gcaatatcct tcccgattct gacaccttct tgattgaaac attcgatggc
    84961 accaatcgac atattgtaat tgctgacaaa aatagcagtt gccccttttt ctaataatgc
    85021 ttttgccccg taatagccgc tttttctaga atagtctcct gtaaagacct ctaattggat
    85081 cgatggatca ttttggaccg cttctttggc tcctgctaaa cgttctcttg ctacgtagtc
    85141 tgtttgagtg gcagcaataa atccgatttt tttatgtcct tgttcaccat gatgagcgat
    85201 cacttttgct acactttctc gatcattcac taatattgta tcaatacctg ctggtccttc
    85261 tggacaattc aatgcgataa ctggaatact catttttgtg agcatttcaa atccagacca
    85321 ctcttcttcg gataagaaga caatcagccc atcgatcaca tgcttcatca ggtattcaat
    85381 tttttgttca attttttctg gctgatcggc aaacccgctt aataataagc tatacccatt
    85441 ttcttcagct actctttcga tccctgagac aacttccgac ccaaaacggc tggaaatccc
    85501 gtttatcaaa agtccaatag agaagcttcg attattcttc aaccctttag caatgatgtt
    85561 ttctttatag tccaacgctg aaatcgcttc tgctattttt ttcatgttct tttccttcag
    85621 ttgctgacca ttcaagtaac gggaaactgt tcccactgaa acaccagcca tcttagccac
    85681 atcacggatc gatgccatac attctcactc ctgccagtta catttgattt ctctttcttg
    85741 ttgttcgatt atgatgaccg cattctttgc atagtgttgc ttgtcatcaa tatccatata
    85801 actaaagtct tcagtagagc aacttcctct cactattaat tatacttaaa caagtatttg
    85861 aaccggttca tttttaatat agcatttttt taaaagattg caacactttt ttaaaacgct
    85921 ttctgaaagt ggcggatttt ttgccttttt aaaattttat tctaaaattt actctatttg
    85981 tgggtgtttt gtgcgttttt ctcttccatc cgtttgaagt tttacattcc aatggtataa
    86041 tttctttatc ctatcaaatg ggggaagtat tttgaagaaa ttaatcgtac tatttatttt
    86101 gtctgcggga cttttgacat tgactggctg tgatttgttt ggcggctctg accaatcctc
    86161 ggacgaaaca accgattctt ctgtcttaaa agcggaaaaa gcagatacca ccaacagtgt
    86221 atatacgcta aaagtacgta aagatatgga tttatccgcg ggacagttga catttacaga
    86281 taaaaaaatg gaatggacac gcacgtatca gacacaagga actgattctt ctgaatcatc
    86341 tgaagaaaaa acagtgctga cagatatcaa gatcactacc aaagatgacg aatatattat
    86401 ttcaggaaaa gaaaataaaa aagaaacaac agtcatattt acaaaaatcg gtaattaccg
    86461 tttgaaggat gaggatggca acatctacag tctatagtgc cgtctgttgg atcttctttt
    86521 gtttctcccc ttcttttctg ctatagtaaa gaagcaagat gattgtaaag gagacgaaat
    86581 ggatgatcga tagtcctgat tattgtacat gtaataacaa caaaaatatc catacagaat
    86641 ttaatgacca aggaagcttg agcatatgcg acaactgtca caaactagtc aaagattcat
    86701 ttaaaacatt tgaatcttat cctgttcaaa attatgtaaa aagtagaaga agataaacaa
    86761 atccaagcaa aactcactat ggctgatttt tatgaacttc aaactcagct tcttcctttg
    86821 atcaagcttc atcagtaaaa caaacagtgg atcatttcag tttacaaatc aaagagtaaa
    86881 gatttattta tttcaaatat ttgaatataa aataaccaaa cgatagaaag gcttattcta
    86941 catcacgtag taatttttct ttcccgtcgt ttggtttttt atttttagcc taattcttga
    87001 ccttttgcat gctggttatc cgtaaaatat tttccagcag gctttccttc caattcagct
    87061 aatttttctt ggatctgacg gatcaccttt tttgcatctt ctggattttc tacaaaatcg
    87121 aatttatccc catccacttg tattttagga catacatcaa aatcttcata ccattgatta
    87181 tagcgggtgt tcaacgtttc ataataggta tataacgtct catcgctttc tagctgttca
    87241 tagtcacgcc cacgtttttt gatacgttct agcatcgtgt ccaaagaaac tttgatatgg
    87301 accatcaaat caggccgttt ttttggagca acatcatcta actcgtttag catcgtatct
    87361 aataagctat cgtactgctg tacttcgata tccgttaccc gacctaaatc agcgtttaga
    87421 tggaacaaca ggctatcttc atagatggat cggtctagca cattgtcatc gttcactaaa
    87481 gcatttttca ttgctaaaaa tcgcttgttc aaaaagaaga tttgcaataa aaaagcgtac
    87541 tgctcaggat ttgaataaaa gagcggcaat acttcgttat cttcgacatt ttcataaaat
    87601 ggtttagaat caatctcttt tgcaagcata tccgtcaaac tgctcttacc tgcaccaatc
    87661 gttcctgaaa tcaaaatcac tgacatacaa cccttcctct tctataagta ctcgcctacg
    87721 taagtttcaa caggcaatgt ttcaaaatca tattcacgta cagcttggtc tgattttaaa
    87781 tacgtatgga gactttgtgt aatcatcaag ttcgtaggta ccgtctcttc ttgtacaatg
    87841 atcatcggtt ttttcaacat agttgccaca cctaattcgt aagccgttcc tggatcgatt
    87901 gtttgatgct caaagtcaag gatagcaaca acaaattctg catttgtcag ttcttccata
    87961 tctttttcgt atacttcctg cgcccatcca gcgctgaata gttcataatt gctttcttgg
    88021 tgatgacgtg gagagtagaa acttgtgact gttttgtttt cctccaacgc tttttcgata
    88081 cgacttactc gatcgatttg ctcctctgaa aaaaatggtc ctgctaaata tatttgactc
    88141 attattttgc ctccttcaat aataactgat ttttaataga tactgctcgt aattcattga
    88201 ccagttccaa tggattgttg gaaaagatta cttgatccaa ccatttttta tccataaaat
    88261 cctcttttgc aaaagtttct aataattgtt gcaagccgct gtaataaccg ccaatattca
    88321 atattccgat tggcttgtcg ggcgtcagac cgattgctat ccaagaaaga agttgtgaga
    88381 attcctccaa tgtacctaga cctccaggga aaacgaggac agcatctccc ttttcaaata
    88441 ataatacctt tctttcatcg atcgtttctg taggaataaa tgtagtaaca tcttttccag
    88501 gcaattcagt ttcaaaaagc ccattcggat agatacctgt gacttttccg ttattttcca
    88561 gtactgtttt actaatcact cccataatcc cggagtatga accaccgtaa accagttcga
    88621 tttcttcttg tgccatgtat tttcctaacg tttgcgcaat aaatttgtaa ctttctttat
    88681 taccaaaacg ggaaccgcaa aaaacagtaa gtttcataaa aaaacactcc ctaactcaaa
    88741 agtctatctt cattctacac gtgttttttt aaaataaaag actagatttt gtagtttttt
    88801 agtggtatat aggatagacg ccactatata tagtatttag aaaaaaatca tttttcagcc
    88861 attttataga taaaacaaaa ataaataacg tgttttcatc gatatgaaat gacttactta
    88921 tagaagatac tgggatttcg tcctatatgc caataacgtg tattatttta aacaacaaat
    88981 acttgtttct tttattaacg aaaaaatcat tttgttctcg tgttatgttt cactgataaa
    89041 tgatgtttct ctaaataaaa aagccgacga actaaacgat caaaatttga tcatttttgt
    89101 tcatcagctt ctcctaaaaa tctttttgtt aacgataaat agctggattt gtaaaaatat
    89161 cacttgaatc gtcactgctg gaagaaaatt cagtgataac cgcacctgtt gcgcctgcct
    89221 ggaactagtg tttgatattg ggctcgaacg tgtactgatc tctagcatga agaataattt
    89281 ctttttttac tgtataataa ctttctttcc tttttggaat agtacaggaa agtttttttg
    89341 tttcctttcc ttcgacataa ggtataccag accctttcga caacgaaagg ttctcatttt
    89401 tccttcatcg tcatttcaag gagggtgccg atgctctgga cagtttcgat cgctcctaaa
    89461 ccaaaatctg tatattcgat tctttctaac tctgattctt tcataccatt cctgtctcaa
    89521 ggtacatcta ttgtactttt ttcttgtaat ccattctgcc tctcctaact aattgtcaaa
    89581 tcatcccaag atatgtcttc ttcctctttt tcttcttgga tgatttctgc attcggatct
    89641 actggttttt tcaataataa aatggttatt cctgtgacaa aagaaccagc taacaatgca
    89701 ccaatgaatg cccatggtct ggtcatcgta gcgactgcaa acattcccga tgccggaata
    89761 cggctatctg cgccccaaaa catgcttaat ccgccaccta ctgtcccacc gactcccgtt
    89821 gctatgacat tgcgtgccaa gtcgttcaat acgataggga aacatccctc tgtgatctga
    89881 cagatcccca taggaaaagc ggtcttcaat gtatcgattt cttgacgatt gagtatattt
    89941 ttacgaatga ttttccctaa gaaataagcg atcgtcaagc cgaatggggt taccatcgaa
    90001 gctaaaatca atacagtgat tggttcatag attccttctg aaaatcgtgc cacaccccct
    90061 tatccagaat aaatggtaat ccagaaacag ccgtgtatct gcggtaataa gcctaaccaa
    90121 acgaaaaata tgagaagcta tttttgtttg gctgttctta ttacttgatg cagggcagct
    90181 ttttcacaac ctcttttttt atttatgttt cataatcaat atggtaagga tgcagctccg
    90241 tatggtagac cgcctccgaa tattcaatca tttccccaat ttgcgtagac gatttccgta
    90301 tccgtttgat gccgatctgt gcgtctgttt tcagaattcc ttgttcttct tctgttaaaa
    90361 atactgccga gaaatcatca gaaaatgagt caatagtata tccttttttc gtcagcaaac
    90421 gatacaaaga ttctttgcca aattcttctc tgctgaattg catcatttct tgtggaagat
    90481 aatgaacaaa ataaatataa ggctgattgt tcaaataata taagcgctta aaacaaacag
    90541 cttgctcacc gaaaaaggaa aacaaaggat cttccttctt tatatggacc aattgcaaat
    90601 ccagcgtttc tttccggact tcatatcggg agttctccaa gatttgcgta aagcttgccg
    90661 ctttggataa tcgattgtaa ggacgattgc ttagaaccgt cgtcccacga ccacttttct
    90721 ttgcgacata ttcatctgat gccagcagtt cgattgcctt tcggacagtg attttgctga
    90781 cttgaaacag ttcttctaat tcactttctg tcggcaacat cgaaccgact ggatattttc
    90841 ctgagaaaat atcttcttta attttatctg cgacttccaa gtatagtaca cgtgtccttt
    90901 tcataacgtc accctttgct ttactattac taaaagaata gcacataaaa aataaaaaaa
    90961 gaacacaaat cacatgtgag aagtgtgttc tttttcattc agctgcttta attacaagtt
    91021 tacgccattt gaggcaatta cttctttata ccaatcaaaa gattttttct ttgatcgatt
    91081 cagtgtccca tttccttcat cgtctagatc cacatagata aagccgtaac gtttactcat
    91141 ttctcctgtt gatgcactga caagatcgat acatccccaa ggcgtatagc ccatcaaatc
    91201 tacaccgtct gctactgcat tagccatcgc ttcgatatga cgacgtaaat aatcgatccg
    91261 ataatcatca ataatcgtgc catcctcttc catatgatca atggctccaa gaccgttttc
    91321 aacaatgaat aatggtttct ggtaacgatt gtataattca ttcaatgcga ttctcagccc
    91381 ttctggatcg atctgccagc cccattcact tgcctcaaga aacggatttt ttactcctcc
    91441 cagcaagttc ccttctgaag ttgctgcttg tggatcagtc tcattgattg ccgtagacat
    91501 ataataacta aatccgatgt agtccactgg atattctttt agcaactgga agtctttttc
    91561 cgtttgctct aatttttccg gatcgactcc atatttttta tgggtacgcg ctgtgtatgc
    91621 agggtattct ccacgtactt ggacatccgt gcagaaaaaa ttgaattctt ggttttggat
    91681 cattgttgct gcctgattga ctggattggc atcgatgctg taagttgttg catagataat
    91741 catgcagccg atttggatat ccgaacgcaa ttcgtggccg atttttacgg ctttgctact
    91801 tgcaacgaat tgattatgcc atgcttggaa aatattttgg tactctcctg ctccattgct
    91861 ttttactaat ccttgactta aagctggaaa gtgaaaggcc gaattgattt cattgaaagt
    91921 catccaatat ttgactttac tgctgtatct ctctaatact gtctgagcaa atcgttcata
    91981 gaagtcgatc agttttcgat ttttccagcc accgtattct tttgccaaat gaagaggcat
    92041 ttcgtaatga gaaatcgtga tcacaggttc aatatcatat tttaagcact catcaatcag
    92101 ctgatcataa aattctaatc ccgcttcgtt aggagtacct tcgtctccat ttggaaaaat
    92161 tcgtgtccag gcaatcgaaa aacgataaca tttgaatccc atttccgcaa acaaggcaag
    92221 atcttctttg aaacgatcgt aatgatcgat tcctcgatga ttcgggtaaa tatatttttc
    92281 ttgatcaatc gtccagtcaa attcttcact gccgataatc gcaaagcgct gcttacctcc
    92341 aggcatagca tctgcaacgg atagtccttt tccgtctcga tcataagccc cttctaattg
    92401 atttggcagc agttgctcca ccccataaaa atttttctga aaaacgtgat tgcatcctga
    92461 tttcctcctt attttacaat tgccagaaca tcttcgtttg caataatctc tttttggtct
    92521 aattcaagta tatcggcaaa tgcatcagta ttcgtaatga caactggagt gattacgcta
    92581 tagccagctg ctctaattgc ttcgatgtca aaacgaatca ataaatctcc tgctttgacg
    92641 agatcccctt gtttgactaa gatctcaaag ccattcccat ttaattctac tgtatccatc
    92701 ccgatatgaa tcaaaatctc cgctccgtca gtcgttgtga tccctacagc atgtccagtt
    92761 ggaaaaatag tcgtgatctc tccgtctgca ggtgcaacta gttctcctac ttctggatca
    92821 atagcgatac cttttcccat cacgccagaa gaaaaaactt ggtctggtac ttcactcaat
    92881 ggcagtactt tacccgttaa aggacttttt aaggtatgcc gtgctgaagt aatcggttct
    92941 cctgcattcg catgtttgtt ttctaattga ttgtcttgtg tttgttcgtc aaatcctaaa
    93001 atcaatgtac ctacgaatgc aagaacaaaa gcaattcctg tagctattac tgctactgtc
    93061 acatttgact ctacaccatc caccgtatta atgaaagtcg gaatcgtcaa taagctgacc
    93121 aaactgctgg agaaagcttt tactccggaa aatccgataa tagctccacc aatacctcca
    93181 gaaatacaag cggcaatgaa tggtttcttc aaaggtaatg tcacaccata cacagttggt
    93241 tcagtgattc caaataacga agtcactgta gaagaaatcc ctaatgctcg aagtttcgta
    93301 tcttttgttc gcaatgctac agctaaagca gccccacctt gtgccaagat ggctggaaga
    93361 agcattggca tcaatacatc aaacccatat tgttcgatat tcaaaaacat gatcggtacg
    93421 aatccccaat gcatgccgaa catcacgaat acttgccata aacttcccat gattagacct
    93481 gctacgattg gactaaatcc ataaatcgag ttgaagagac cgcctaaagc attaccggca
    93541 accgtcccga ttggtcctaa agcaagaaat gttaatggaa ccatcactac taaaacgaca
    93601 agcggaacta aaatcatttg cagaaattgc ggaatcactt tttttacgaa tggctctaat
    93661 ttactttgaa cccatacggc tagaatgatt ggtatgacag aagaagtata accagatggt
    93721 gaaagaatca ctgggatccc aaagaaactg atagcttctc ccgcaccagc aactgctgtg
    93781 atagctggat acacaagtgc catagcaatt gctactgcta aaaactggtt ggctttgaac
    93841 tttttagctg ctgtaaaagc aagcatgaca ggtaagaagg taaagacacc atctgctgca
    93901 gcaaacaata tttgataagt accgctatca gctgtcagcc agcccatcac cgttgccaat
    93961 gataagaatc ctttcaatac cccggcggct gccatcgccc ctagaaaagg tgtaaatata
    94021 ctagagataa tatcgatcag acgattcaaa atatttttgg actcttcttt tccatcctcc
    94081 gaaactgcaa gaccttcctc atccacgatc gattgataaa catctgctac attactgcca
    94141 atcactactt gatactgacc gccactttgt acgacttgga tcacgtccgg gtcttctttt
    94201 aacttttgcg tatctgctaa agattcatct tttaatctga atcgcaaccg cgtagcacaa
    94261 tgtactaaac ttttgacatt cttttgtcct cctaccgctt cccatacacg acgaccaact
    94321 gcttgattat ccattgtttt ttccttcttt cttttttatt taaaaaataa aaacccagat
    94381 tgaaaaaaac agtcacaaac attcgtgaac ctattttttc aatccaggtt ttgcctgcca
    94441 tacagtaaca atccttatga ttggatgctt tttttctcac ttactactct ttgaatatga
    94501 atcgttaaat aaatctgctc tgcgatcccc atttcctgtt tttgcgtttg tcgaagatac
    94561 tcattgatcc gttcgacaca atgaaacgct tttggatact ttccttgaac taatgcgtag
    94621 agaaattcat cttgctcgtc agatccttcc cctttgagat aacgctgggc aaaaaactgc
    94681 agatgagtaa tgatacgctg ataattcaaa gattcttcat cgaacacgat gccgaagaat
    94741 ttactgatga tactcagtat atctcttacc attgtggtag cggtcatcgt cacttgcatg
    94801 tcttcgtttc cttgttggct attcacaaaa tgaaaggcaa taaaaccggc ttcatcctca
    94861 gaaagttcca cacccgtctt ttgtttcacg aacaaaagag cctctttcgc tgcttgatat
    94921 tctttcggat aaaatttttt tgtttcaaat aataatggat taggcagttg gatattttct
    94981 tttgctcgtg tgatcgcata atgaagatga tcggtcaatg tcagataaat attaggcgaa
    95041 aattcaactt ttagtttatc ttcagccagt tcgactactt gtttgaccca ttcgatctcc
    95101 tctgccggaa tatcagccat cagctgctgg aattggtttt tagcaaaaga atctcttaaa
    95161 acaaattctt tttggaccgc ttctggcgaa atctcgtccc caatcttttt ttgaaaagct
    95221 agtccttttc ccatacaaac gacttcttcc ccgaatccat ttttcgaaat gacgacattg
    95281 ttattcaaaa ttttatcaat tttcattttg cttcgccctc tcaagaaaaa taaaaaaacc
    95341 tagaattcgc ctactgtttc ttagctgaat tctggttttg cctgccgtac agtaacaatc
    95401 catttcttat tcaaaatcat cataccatcg aatttttatt tatgcaagcc ttttcatata
    95461 aaaaataaaa aaactggaac acaagtctat ctagaaaaca accaaatcag agatgcacct
    95521 ctttgcgttt ctcttttttt cagcaaattg gtttttcctt atcgattcat atcctttggc
    95581 tgtttttaat ctgtaacgac ttatgtccca gtatcctaaa atgtttttgt ctctagattg
    95641 aaagcagatc tcatatcatc tgtcgcatct tttatcgatg taacactttc cagttctcct
    95701 tgtacaacta gtcgcgtgac ggcgtccatg tcgccacaag taattagtgt gacaatttct
    95761 tttccctcga cttcattcag taattgggta tctgtaggag caactttttc tttaaaaaat
    95821 gttttgtatg tatacacatt ttctaaatct gtcaaataga tcttggcacc catctctaaa
    95881 ttttctagcg gtgtaaacag caattcaggg ttcgttgcac gatggcttgc taaggcataa
    95941 tttccttttc ccatttcttg atctggagat aatgttcctg ctccgtaaag tagtgacgta
    96001 ttatccaagc ctttgaaaac cggtaaattg attgaaactg aagggactgc gatactagca
    96061 atcactggta gatctgttcc tctcatttgc gacctcatga ccccttctgt cgtcattggt
    96121 tctaccgcat caaagtcaaa actgacatct ttatcgttat tctttttcag atcttctttt
    96181 gttacattcg ctatagcata tttatctcct gtctctctga caaaataatc cttgatctgt
    96241 tcattgaaaa tcaaagctag tcctactaat aacaagagga acaagaggat attgactagc
    96301 catctttttg cttttccttt ttttttcatt ttctctccct ccagactcat tttactgttt
    96361 ttcttttgct ctttccaaca gccgaatgac acatttctac aactctgtgt atttttttcg
    96421 tacacctgcg cttttttcta caggatattt caaattattt ttgatcaatt tttcttcaat
    96481 gatctcatct agatccaggt gaaggttgtc tgccatcatg tatgaataga tcaatacatc
    96541 taccagttct tctttgattc gttctaattg tgtttctttt acttcttccg gcgttttcca
    96601 ttgaaaaagt tctaacaatt cagatgcttc caaagaaata gagatagcca aatctttttc
    96661 gttatgaaat tgtcgccaat tacgttcatc tctaaactgg ttgacttttt ccatactatt
    96721 catttgcttg ccttcttcca atcacttctt acttgattaa tcataccatt tttttacata
    96781 aaaaatagat gatgctttta aaaaaactcc tgttttcttt tatttaaaat aaatgtcata
    96841 gaaaatcaat aatttaggta gccaccatgt gtatgcagta gcgtgtcttc ttcccttgag
    96901 gctttttgtt tttcgatacg ttcttcttcc caaacagaca acgctactag aatctctctt
    96961 aatgattttc cttcttcggt gagcgagtac tctactttag gcgggacttg gttataggct
    97021 tttcgatgga tactttcatc ttgttctaac tctcttaact gctgggtcag catttttttt
    97081 gtgatcgtag ggatttgctt gcttctccac gcctaaaata agcgatattg ctcttccctt
    97141 tatctggtgt aagcaaagca gttagcattt tgacgatcgt gggttccgct tttcacttct
    97201 tatctactta gtatcatgaa gtatactttc gtactaatac taagtagcgg aagtgtcaac
    97261 tactttgttt aactacatag caaaagaaac agaagggtga caacggtcat cacgcttctg
    97321 tttcttttga atatgctgtg ttgttgtctc tatctccgtg tagactttcc tcaaacttat
    97381 cctttgacag taagtcagta ggctgatttg ctctttctag atgccagata catttctaca
    97441 aaaaaatagt gattctgttt tgaaaattcg atttttagtt ctgcattttc gtaaacatcc
    97501 aacatttttt tcgcactgta tagacctaac ccgccatttt ttttagaggt ttttcctctt
    97561 ttgaccatct ccgatagcgt caaattcgtt ggatttgcct tgttcgctat actaaaacgt
    97621 gatccctctt tttcttccag cagattgatc gtaatcggac tctgatcggc tacacgatga
    97681 tcgaatgcgt tagaaataaa aatagataaa cagcgaataa aaacaaccag atcaatcggg
    97741 attgttttca cttcgacagg aataactact tggatcggga ttttctccga ttctgctttt
    97801 tctagaaatt ttaaaaagac acccctgaca gctggggata caatatttgt tagctgttgt
    97861 atttgcggtt tttcaaaaat agctgcagaa tgatcttcta atatttctaa aaattccaac
    97921 gtttcttttt tattttcctg aagagtaatt tttaatgaaa acagtagact tttataatca
    97981 tgtttgaatt cctctagatg atggtaatat tcttcattta tttgatacag ttgaagcgat
    98041 tcctgatgtt gtctttcttt tacttggaaa ctgatcaaca taatggaaaa aaacaaagaa
    98101 aaaaaactga tgactatcga caaaagagat agaagcagat aattagatga gcggaagtga
    98161 acacttccca ataccaagta aatcacgccc cagcttaata aaatacaaat acctccaaaa
    98221 tagtgttcag ttggataagt aaaaagcaag ttgagaaatc tcgtctgttt gtctatactt
    98281 tttactaata gatagaaaat aaatgcgata agtagtgcaa aaaaacttgc tgttccaaga
    98341 tgtctctttc ctaaataatc catcagatca aaaaccagaa aaaagctgag tccagtgata
    98401 gcaaaaaaaa gattactgat caaacagctg ataaacaggt ttttcgtagt aaaataaaaa
    98461 aagaaacatc aataataagc caactaggta aggaaagctc actttaggga taggaagtaa
    98521 aagtgtcacc accatcaaag ctatacaacc aaagctgttt tttactagca gttgtttcga
    98581 aaagaataaa tagataccta aatctaaaat caaagtaaag gtcaaataaa gtgtcactgt
    98641 tgcgaccatc ttattcctcc attgttttgt ttcaaaatgt acacatattt ttttaatagg
    98701 agcctgcata tgaaaaagta ttttatcata gaagataacc agtttcacag cgaatggatc
    98761 atcagagaat tggtcaatca tcatatcgag aatatcgtgc agctcacttc tatctctcaa
    98821 atcaatcagt tgatccagtt gggcactatt gataatcacg atgttttctt tatcgatatc
    98881 gacttgaagc aatcactcac aggtattgat gtcgccgaac aaatacgtaa aaaaaatgca
    98941 catagtaata ttgttttttt caccgcttat acgaattttg cagtagagat catcaatcgg
    99001 aaaatccttc cgattggata tatcagaaaa gacaggaatt tatctgaaca aattcgtcaa
    99061 gtgctagaac agatcaattg gaaagaacag cagatcgtaa atgtcgataa aatctttatt
    99121 gatcaaaaag gtggaagtct cgtcctgtat cctcgggaaa ttttatatat tgaaagtatc
    99181 aaaggtttga aaaaccaagt tatggtcaaa acaactacag aagataaatt agtgaatact
    99241 tctttaaaac aattgaagac agagttagaa aagtatgctt actttttact tttaaaatct
    99301 tactgtatca acttatcgca attgcagaaa attgattctg ctcattatgt gttagaattt
    99361 ttcaacggtg actccttact cgttggtcga aagatctttg aaaagacaaa ggaacgtttc
    99421 catgacttcc aaaaaactgc ttcgagttga tgaataagag ctgagacgta agcatagcag
    99481 atttcaggga gtgggccttg aatcggctcc actccctgaa atcgttgata tgattttacg
    99541 cttcctcttc tgtaggagca tctgttaacg accatgtgaa tgttgaaacg tagttgtcta
    99601 cagcataatt ggatacagga acaaataatt ccactgattg tctcccttgt tccacattct
    99661 ctcctaatga ataaatccat gtgccaatcc cttcatttgc tcctgcagtt actagatcta
    99721 ctgcctgatc tgctgggatt tcgattcctt cagcgccagt tccagaaacg gtagatggca
    99781 ttccactgct attagttgcg ctatttcgaa tcacggcgtt tttgaatttc acctttgaac
    99841 cagttagttt attcgtatca gatgttgtac caataaattc tgttcgtttg actgataatt
    99901 tccaaccggc ataatttccg cttttatccg ttacttgtac gaaattctgt acttgtgttt
    99961 gtgctccagt actgtccgtt ccgctttgta atgcagcata tactgttttt gctgtaccta
   100021 acttgattgt tccaaaatca agatctggag cttggtcaat cgtcagtaat ccggatgttc
   100081 cctgatttgg ttcgtcaggt gtaaaaggag tatcaggatc atttggatca acaggaggaa
   100141 ctggaacaac gtcttcagga tttgcagcat ctggtttggt cacagaaatc gttccttctg
   100201 tagtggctga gctcttattc tcagcaaaaa cactttgtgt acataataat agacttccag
   100261 ctagaacggt acttaatgca attgtttttt tcatttcttt ttccttcttt cttttaaaat
   100321 aaataatcca gcaaataagc caataagaat gactccaaca agtatcagcc atcgccagtc
   100381 aaatgtttct ggctgatttt ttaaatcaat atccttttca ttcaattggt ccgctgcatc
   100441 atcagttatt tcaaaatcgg tatggagatt ccagcgtttt tctttccaag cacccttcac
   100501 aaccgcttga taatgtcccg gagctaattt ttttccttct aatgggacaa gtaaatcaaa
   100561 atttgtattg ggtgctacat ctattttttc tttttttatt gaaaggtaag gctcttttgt
   100621 ttcttttttg tagatttcaa ccgatgtagt caagccgaac atataagaag catttggatt
   100681 ttgaagattc gccttaatca catttcttcc atcgctttga tccgcataag ctttttttaa
   100741 tttcaaatct ggggaagact ctttttcgct atttcaaatc aagattgctt tcacttgaga
   100801 aaactgattg acgacaccaa ctgtactttt gttagaaacg ttctcttttt tttcttgaaa
   100861 cgtgatccct cctgcgacca caccagccag ctctttttct ggcgctttca gtgaaagtgt
   100921 ctcagtgacc gcactttgag gaggaacagt tatttctccc actgtttttg ctaagttttt
   100981 catatcataa cttaatgttt catcaaattt actttttgat tctccatatt cgatcacacc
   101041 gtttgaattc gtcgtagcgg agtggatcaa tgtctcaact gttactgatt tatctgttcg
   101101 gttaaagacc gtgtagggga tttcctgtgt tttcccaggc tccatcctta catttatata
   101161 tgttttgttc ttatcaatct gattagccgg taattcaaaa tctaccgcaa aattgaattc
   101221 ggaggcatgg acaggtgtct gccaaaggat gaatccaagg agaaggatca taagtaaaga
   101281 gcagttgttt cgatgacttt tattccatat tcgattcatc aatcatcctc cttgatcttt
   101341 attctgtcgg cgcatctgct aatgtccatg ttatctctgc tgagtaatta ccagctatct
   101401 gattttcttt ggttaagaca agtttaaacg cccgaccgtt atttaaatat tctgaataat
   101461 ctgcttgcac attcgttgaa ttttgtcctc tgacaatttc cagttcttct tcattcacta
   101521 attgatactc ctctcctttc ttgaaatata ggacatcctg catagaaaat cctgcatcat
   101581 ttgtgaaagg ctgagataat tttatcgtta agatccacgg atttttcgtt tctcgctgat
   101641 cataaatcca taatttttcc tgtatatcca tttggccaaa tgcttcttgt gtcaaaccag
   101701 ttgctttgat ctgaccaaaa tcgagtttgg aaggggcaag aaatgagaga ccaccttcta
   101761 ctacgatctt cgtagcaggt gcaaaaggcg gggcatcatg ataaacaact ggcgtatcac
   101821 ttggattgtg attcccaatt tcatcgttgg tacttggctt gttctgcaca cccttagcag
   101881 tagcttctcc tgcttggtcg tttaatacaa tttctaatac atctcctgca aaaagttgat
   101941 tttctgggat agaaagaaca aattcccctg tatcatcaat agttgtttct gacaaaacag
   102001 cttgattttt tttcaatgaa accaaggctc ctgcttcacc tgtacctgtg atcgtgcgag
   102061 aagctgcatt gatcaatgtg gtacttaaat tagcaggttc aggaggaatc acatcgactg
   102121 tcgttttggc agagtccagt tctgtcactt cttggccacc tcttactttt ttagcagcaa
   102181 caacttgcac ttgatcctcc gtttttaatc tctcatcatt gggtacttga acttcgaaca
   102241 agccgccttg ttcgccttct ccccatgggt tatatcctgc cccttcattt tcatctgttt
   102301 gtccttgcgt gagagcagta atttctacag atgatttcgt cgtatctgcg taagtaatac
   102361 gtaaagtcac ttctacttcg cctgtccaag catctcttgg ctttgcctcg acaccttcgg
   102421 gaacaacgac atgcccatag atttttttat ctgcattcgt tggcactctt aaggattcaa
   102481 tcatcgggag ctgattattg gcactgattc gattataatt tttcattccg gcacctgtct
   102541 gagcaaattc atttgttaaa cctgcactag ggcttgatac gaaattgcct aagtcggtcc
   102601 cattgatcga taagtctgtc atatcagaaa aataatccgg gtctttttca aagttatcga
   102661 atgttgcgcc tgtttttcgc cataaagcga tttctgaatg ggcgatcttt aaagaagaat
   102721 ctccatttcc ttggaatacc cagccgccta tgccattggt ctcgcttcca atccgtttgt
   102781 tttggaaatc aaaataggta ggagattcta agtccacatt caacacatcc ccactgatga
   102841 tgccggtctt atcttcccct gttttcccga ccatgactaa ataagttttt tcacctgccg
   102901 taaaatttaa atcaatatct ccagttgtat ctacagttgc tccggaatct gcgcgtatat
   102961 cgatatttga tttttctcca gtgactgtaa aatcagctga acctggactt tctagaaaac
   103021 cagaagcgtc ataaaattgg atcgcttgat ttccttgatt gagtctgttc acgtaagatt
   103081 tgccatcacc tgtatttctt accctcaatg agcctccatt ggttactgtc agcttttgcg
   103141 taccattctc aaaacgaact gcgctggaac gcccactctg cttatcgatg tcgataactg
   103201 atccggctcc ttctacgatc aaagaaaggc cttttcctac aaaacgcatc ccattgttcc
   103261 cgggttgatc gtcatctcca gccattttga ccgagatttg tccaccactt gatacatgga
   103321 tttgactaga atctccttgc aagcgaaatc cgcccgtagt tgctgtattg atggtgattt
   103381 tcccaccatt cgatacagtg actttcgatc ctgaacctct catttggatg attccgcgat
   103441 tgttgtcatt ggtaatattg atctttgtat ttaccgaaaa ttcgcttccc gaaccactga
   103501 cttcaaacat gacattacca ggtagcgtat cgactgcctc tccttcatcg ctaacgccat
   103561 ctgcccgatc ataatcaaga gagacctttg aaccgcttaa gatatggatt cctggcgctg
   103621 tttttccact accagtctca tctcctgaat ctagaaaacc gtagaatttc cctagatacg
   103681 gtccataaag ttgactacca ttgatcacat tcaattgata gcttctacaa aaataggctt
   103741 tacccggagc ggcattcagt ccttccttca ctggttggac atccaacaca ccggaaacac
   103801 catctaatgt gacagttgca cgaggagcgt aaatcagtcc taatttggac ccatcataca
   103861 aatcaagtgt cccggtaaat tttatttctc ccgtaaaatg atatctgctt ccccaaaaat
   103921 cggtcatata agcaatgata atggcatttc catcgatatt tggtgtcaat ccacctggat
   103981 gtgcagctgt tcctttaaaa ttctggaact cgatcgactg aggtatctca ttgatataaa
   104041 tatggtgtgt gccgaaattg tgagcgaatc caccaaaatc aataacgata tctcgtttga
   104101 tctctaattc cctgtctaaa gtcaaaggct gaatcagtcg gatcttagtt actgattcgt
   104161 ctgcgagaag ctgcgccagt tcttctgttg tggcagcttc gctgtaccca tccgctgaaa
   104221 cagctcttgc cagtgccgct tcactgctat cagacgtttg ttcagctact tctgaggtct
   104281 cacttgtctt attttcttct tgccttttat tagtagaagc ctcactttga gattctgtag
   104341 tttcagaagt aatcgattct tctgaaaaag tagtcttgtc aaaactttga ttctctgatt
   104401 gcgttgattc gtttgttttc tctacatcgg caaaaacgga tgtcaccatc aagagaggga
   104461 agacaaacaa aatcgacgca atcagctttt ttacacattg attcattctc caccatcctc
   104521 tctgacgttt tgacaatttt attttatcgt tttaatctat ttccaattgt actttcatat
   104581 ttaaaatatg tatttttatg gaaaaatttt tctattaggt gtaaatttct tttttgtaca
   104641 aaaaaaaggc tgtgacaaaa gtcttgtcac agtcccttat cccgaacaag cggtgttctc
   104701 ccgccaactc ctcggtcaca acctccattt taacaataaa cctgtaaatg tgagggcaat
   104761 actttgattg tcacaggtaa tttatcccct tcatctccat caacattcgt cgtcaattct
   104821 tcctcatcag ctaatgacac aactaattgc tcacaagtaa ggtaggctag atttttcgta
   104881 gattcatcta ctccttttaa taggtctggc aatgttttaa gcgtatcgat caaagaagaa
   104941 tcttttaaat aaaccaaatg gagcttacca tcatccactt ttgcatttgg aagtaatgtt
   105001 tcaaaaccgc cgactgagtt agttagtcct atcagcaagg tactgctctc aatttcttcc
   105061 ttctttccat caacttctac gtgaaacgag taggattgtg tggaagctaa ctgtttgatt
   105121 cctgacatga aataagctag ttttccaaat ttcgtcttct tctccgcatc tacatcattg
   105181 attgattcag ggatagagcc aattgcgacg acattcataa aatagtcgtc atttattttt
   105241 ccaatatcca atggcttgac tgattcaatc gaaaaatgat tgatcgcttc ctcaggttct
   105301 agcggtatcc ctaatgctcg agccaagtca ttcaccgtac ccaatgggaa aaatccgaaa
   105361 tttggccgat gttcttgttc agcgattcca ctgattcctt cgttgactgt tccatctccg
   105421 cccatgacaa acacactatg atacccttcc gtagccgctt cgcgagtaaa gttttttgca
   105481 tcccctgctt tttttgtatg caagacgacc acttcatcaa acaccgattc caattttgct
   105541 atcgctaatt gctcaaattc ctttgcttgt tcaccgcctg aactggggtt taccactaat
   105601 aaaacttttt tcatcacttt ctttcccttc tgattgattt ctttaatata acgatagcat
   105661 aaagaaaaaa attaggctgt gatgaagtac tgttcatgaa acattcattt attttttgac
   105721 aagataaaac atccatacta tgaaactgag gaaaattaaa acaatgatat aggaaataaa
   105781 agaaaatgat aggcattgta tacctaataa agtaaaaatc ttaggtggca gataaaaaca
   105841 caaaaatagc aagagaatgt aatagcgttt cttccacttt ttgttatcag accttatagc
   105901 gatcagagga ataccaaatg cataactgaa aaactcttga tgtactgtta atatgtcacg
   105961 gccttgaata ataaatgcga caatccccgc tataattagt gtgcctaaca ccaaaacgga
   106021 aaattgatga atatatttta tatacaaatg atccattgta cttcctgcct ttttatttgt
   106081 gagaaaaaca aatccgtata cgtgaataac ttctagaaat aaaagaaatt tgcaaaacca
   106141 ctccatttat ctacttctac gtgcattttt tgatattgtt ttctttattt aagattatac
   106201 agaaaaatat ctagggtcgc tggattctaa gtaaaaaaaa tttttaaaat aaaaagaact
   106261 aaatcaagta gtaattaaac tactgttgat ttagttctaa taaaaagatt tagatgaaca
   106321 gttttattga tttaaatagt tcatattttt tatttatacc gcttatttac tacttgctgt
   106381 actagaatct gaagtgaatg tactcaaaac attttcaaag tctttgtctt tgatttttac
   106441 attagcgtct ttcaatactt cgccaattac tttattctgg aaggtactgt cacttaattt
   106501 tgtgtctgtt gcaatttctt tcaattcttt tttgtattta tccatgtcgt tgcctttgtt
   106561 ttggtttttc accattttaa ccacataata ttccgtagta taagttgaag cattggtaga
   106621 agtgatcaca tcagaaactt gaccatcttt caacttaaag gctgcttctt tgacttctgc
   106681 cggaaccgtt gtagtagtgg aatcaaattt cacttttccg ccatcttctt ttgtcgtagt
   106741 atcagttgac ttgtctttgg ctaatttaga gaaatcgtct cccttatcag cagctttctt
   106801 cacatctttt gcatcatctt cacttgctac ttggataatt tgagcttcca cttctggatg
   106861 gaaagattcc caagccgttt ttaaatcttc atcggtcaat ttgatatgtt tctttagacc
   106921 ttcttgaaag gctagacttt gtttgatact gtctttgaat gtttgttctg tgtaacctgc
   106981 agatttcaat tgtgaatcaa atgaatcacc caattgtttc tttgtttgat catattgaga
   107041 atcgatttct ttggttgata cgtcatctcc atatttatct tcaaatactt gataaacgat
   107101 caactgttgc acagcggaat ctgctccttg catttttttc aagctatcca ttacttcttg
   107161 ttcgctgatt gtaccgcctt tataactaac ggctgttttt tcaccggcat tcgtacagcc
   107221 tgacaataag ccagtgccta gtacgatggc aagtgctaaa aatctttttt tcatttatca
   107281 attctcctac ttttcgtttt ttgcgaattg ctaaaaacaa aggtgttcaa gatgaaaatc
   107341 atcaagaaca cctttactaa tctgctcgat acgtcctgaa tagatataag gctacacaat
   107401 ccagaaagtt cgctcagcag aataaatgtc aagtagcaca tcacacctta atatactact
   107461 tcttttgtta ccgtttttca agtctatctt gcgttccgta tttaacgtaa ctaattctta
   107521 gaacaaatgt tatcgatttt gtttttcttc ttccgctgct gggatattca aatcagacac
   107581 ttttatgttc gattttccag acattttttt gttgttttta ttat
//
LOCUS       DAFEEZ010000002        94657 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000002
VERSION     DAFEEZ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 94657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94657
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.002"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            221..1279
                     /locus_tag="LP245_000099"
     CDS             221..1279
                     /locus_tag="LP245_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBL1518049.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1283..2317
                     /locus_tag="LP245_000100"
     CDS             1283..2317
                     /locus_tag="LP245_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBL1518050.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(2419..3135)
                     /locus_tag="LP245_000101"
     CDS             complement(2419..3135)
                     /locus_tag="LP245_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL1518051.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3104..3889)
                     /locus_tag="LP245_000102"
     CDS             complement(3104..3889)
                     /locus_tag="LP245_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBL1518052.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3880..4629)
                     /locus_tag="LP245_000103"
     CDS             complement(3880..4629)
                     /locus_tag="LP245_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBL1518053.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4927..5451
                     /locus_tag="LP245_000104"
     CDS             4927..5451
                     /locus_tag="LP245_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBL1518054.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5467..6966
                     /locus_tag="LP245_000105"
     CDS             5467..6966
                     /locus_tag="LP245_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBL1518055.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFREEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(7054..7656)
                     /locus_tag="LP245_000106"
     CDS             complement(7054..7656)
                     /locus_tag="LP245_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL1518056.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7760..8716
                     /locus_tag="LP245_000107"
     CDS             7760..8716
                     /locus_tag="LP245_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBL1518057.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(9021..9977)
                     /locus_tag="LP245_000108"
     CDS             complement(9021..9977)
                     /locus_tag="LP245_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1518058.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10151..10711
                     /locus_tag="LP245_000109"
     CDS             10151..10711
                     /locus_tag="LP245_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518059.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10704..11528
                     /locus_tag="LP245_000110"
     CDS             10704..11528
                     /locus_tag="LP245_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBL1518060.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11538..12155
                     /locus_tag="LP245_000111"
     CDS             11538..12155
                     /locus_tag="LP245_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL1518061.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12173..12856
                     /locus_tag="LP245_000112"
     CDS             12173..12856
                     /locus_tag="LP245_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL1518062.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13539..14822
                     /locus_tag="LP245_000113"
     CDS             13539..14822
                     /locus_tag="LP245_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1518063.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14838..15725
                     /locus_tag="LP245_000114"
     CDS             14838..15725
                     /locus_tag="LP245_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1518064.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15742..16578
                     /locus_tag="LP245_000115"
     CDS             15742..16578
                     /locus_tag="LP245_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1518065.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16581..17204
                     /locus_tag="LP245_000116"
     CDS             16581..17204
                     /locus_tag="LP245_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518066.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17201..18492
                     /locus_tag="LP245_000117"
                     /pseudo
     CDS             17201..18492
                     /locus_tag="LP245_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
     regulatory      18851..18948
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            19064..19645
                     /locus_tag="LP245_000118"
     CDS             19064..19645
                     /locus_tag="LP245_000118"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBL1518067.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19648..20955
                     /locus_tag="LP245_000119"
     CDS             19648..20955
                     /locus_tag="LP245_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBL1518068.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21371..21859
                     /gene="purE"
                     /locus_tag="LP245_000120"
     CDS             21371..21859
                     /gene="purE"
                     /locus_tag="LP245_000120"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBL1518069.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21852..22976
                     /gene="purK"
                     /locus_tag="LP245_000121"
     CDS             21852..22976
                     /gene="purK"
                     /locus_tag="LP245_000121"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBL1518070.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSIEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22989..24284
                     /gene="purB"
                     /locus_tag="LP245_000122"
     CDS             22989..24284
                     /gene="purB"
                     /locus_tag="LP245_000122"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBL1518071.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24464..24841)
                     /locus_tag="LP245_000123"
     CDS             complement(24464..24841)
                     /locus_tag="LP245_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518072.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            25097..25825
                     /locus_tag="LP245_000124"
     CDS             25097..25825
                     /locus_tag="LP245_000124"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBL1518073.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            25825..26079
                     /gene="purS"
                     /locus_tag="LP245_000125"
     CDS             25825..26079
                     /gene="purS"
                     /locus_tag="LP245_000125"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBL1518074.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            26081..26752
                     /gene="purQ"
                     /locus_tag="LP245_000126"
     CDS             26081..26752
                     /gene="purQ"
                     /locus_tag="LP245_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBL1518075.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            26753..28975
                     /gene="purL"
                     /locus_tag="LP245_000127"
     CDS             26753..28975
                     /gene="purL"
                     /locus_tag="LP245_000127"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBL1518076.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            28960..30399
                     /locus_tag="LP245_000128"
     CDS             28960..30399
                     /locus_tag="LP245_000128"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBL1518077.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            30422..31474
                     /locus_tag="LP245_000129"
     CDS             30422..31474
                     /locus_tag="LP245_000129"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBL1518078.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            31471..32049
                     /gene="purN"
                     /locus_tag="LP245_000130"
     CDS             31471..32049
                     /gene="purN"
                     /locus_tag="LP245_000130"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBL1518079.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            32046..33581
                     /gene="purH"
                     /locus_tag="LP245_000131"
     CDS             32046..33581
                     /gene="purH"
                     /locus_tag="LP245_000131"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBL1518080.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            33597..34871
                     /gene="purD"
                     /locus_tag="LP245_000132"
     CDS             33597..34871
                     /gene="purD"
                     /locus_tag="LP245_000132"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBL1518081.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            34993..35907
                     /locus_tag="LP245_000133"
     CDS             34993..35907
                     /locus_tag="LP245_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL1518082.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(36040..37605)
                     /locus_tag="LP245_000134"
     CDS             complement(36040..37605)
                     /locus_tag="LP245_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL1518083.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSYFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(37598..39049)
                     /locus_tag="LP245_000135"
     CDS             complement(37598..39049)
                     /locus_tag="LP245_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL1518084.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(39063..40079)
                     /locus_tag="LP245_000136"
     CDS             complement(39063..40079)
                     /locus_tag="LP245_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1518085.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            40299..41387
                     /locus_tag="LP245_000137"
     CDS             40299..41387
                     /locus_tag="LP245_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBL1518086.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            41441..42967
                     /locus_tag="LP245_000138"
     CDS             41441..42967
                     /locus_tag="LP245_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBL1518087.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            42969..44174
                     /locus_tag="LP245_000139"
     CDS             42969..44174
                     /locus_tag="LP245_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1518088.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            44431..45408
                     /gene="guaC"
                     /locus_tag="LP245_000140"
     CDS             44431..45408
                     /gene="guaC"
                     /locus_tag="LP245_000140"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBL1518089.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            45672..47096
                     /locus_tag="LP245_000141"
     CDS             45672..47096
                     /locus_tag="LP245_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBL1518090.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            47557..48666
                     /gene="pdhA"
                     /locus_tag="LP245_000142"
     CDS             47557..48666
                     /gene="pdhA"
                     /locus_tag="LP245_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBL1518091.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            48669..49646
                     /locus_tag="LP245_000143"
     CDS             48669..49646
                     /locus_tag="LP245_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBL1518092.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            49671..51314
                     /locus_tag="LP245_000144"
     CDS             49671..51314
                     /locus_tag="LP245_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HBL1518093.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            51322..52728
                     /gene="lpdA"
                     /locus_tag="LP245_000145"
     CDS             51322..52728
                     /gene="lpdA"
                     /locus_tag="LP245_000145"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBL1518094.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            52890..53165
                     /locus_tag="LP245_000146"
     CDS             52890..53165
                     /locus_tag="LP245_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBL1518095.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            53171..53938
                     /locus_tag="LP245_000147"
     CDS             53171..53938
                     /locus_tag="LP245_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBL1518096.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            54106..55935
                     /gene="typA"
                     /locus_tag="LP245_000148"
     CDS             54106..55935
                     /gene="typA"
                     /locus_tag="LP245_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBL1518097.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            56196..57968
                     /gene="recQ"
                     /locus_tag="LP245_000149"
     CDS             56196..57968
                     /gene="recQ"
                     /locus_tag="LP245_000149"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBL1518098.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            58082..58384
                     /locus_tag="LP245_000150"
     CDS             58082..58384
                     /locus_tag="LP245_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBL1518099.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            58387..59550
                     /locus_tag="LP245_000151"
     CDS             58387..59550
                     /locus_tag="LP245_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL1518100.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            59576..63004
                     /locus_tag="LP245_000152"
     CDS             59576..63004
                     /locus_tag="LP245_000152"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBL1518101.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            63025..64149
                     /locus_tag="LP245_000153"
     CDS             63025..64149
                     /locus_tag="LP245_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518102.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            64139..64576
                     /locus_tag="LP245_000154"
     CDS             64139..64576
                     /locus_tag="LP245_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL1518103.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            64560..64898
                     /locus_tag="LP245_000155"
     CDS             64560..64898
                     /locus_tag="LP245_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBL1518104.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            65017..65577
                     /gene="rsmD"
                     /locus_tag="LP245_000156"
     CDS             65017..65577
                     /gene="rsmD"
                     /locus_tag="LP245_000156"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBL1518105.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            65574..66065
                     /gene="coaD"
                     /locus_tag="LP245_000157"
     CDS             65574..66065
                     /gene="coaD"
                     /locus_tag="LP245_000157"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBL1518106.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            66055..67098
                     /locus_tag="LP245_000158"
     CDS             66055..67098
                     /locus_tag="LP245_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBL1518107.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            67257..67985
                     /locus_tag="LP245_000159"
     CDS             67257..67985
                     /locus_tag="LP245_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBL1518108.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            68101..68346
                     /locus_tag="LP245_000160"
     CDS             68101..68346
                     /locus_tag="LP245_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL1518109.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            68343..68561
                     /locus_tag="LP245_000161"
     CDS             68343..68561
                     /locus_tag="LP245_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBL1518110.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            68697..69236
                     /locus_tag="LP245_000162"
     CDS             68697..69236
                     /locus_tag="LP245_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBL1518111.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            69229..71502
                     /locus_tag="LP245_000163"
     CDS             69229..71502
                     /locus_tag="LP245_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBL1518112.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            71540..72586
                     /gene="holA"
                     /locus_tag="LP245_000164"
     CDS             71540..72586
                     /gene="holA"
                     /locus_tag="LP245_000164"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBL1518113.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(72675..72929)
                     /locus_tag="LP245_000165"
     CDS             complement(72675..72929)
                     /locus_tag="LP245_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBL1518114.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(73329..73598)
                     /locus_tag="LP245_000166"
     CDS             complement(73329..73598)
                     /locus_tag="LP245_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518115.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(74068..74523)
                     /locus_tag="LP245_000167"
     CDS             complement(74068..74523)
                     /locus_tag="LP245_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBL1518116.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(74661..76589)
                     /locus_tag="LP245_000168"
     CDS             complement(74661..76589)
                     /locus_tag="LP245_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBL1518117.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(76786..77619)
                     /locus_tag="LP245_000169"
     CDS             complement(76786..77619)
                     /locus_tag="LP245_000169"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBL1518118.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(77811..78515)
                     /locus_tag="LP245_000170"
     CDS             complement(77811..78515)
                     /locus_tag="LP245_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL1518119.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(78538..79164)
                     /locus_tag="LP245_000171"
     CDS             complement(78538..79164)
                     /locus_tag="LP245_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL1518120.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            79490..81865
                     /locus_tag="LP245_000172"
     CDS             79490..81865
                     /locus_tag="LP245_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBL1518121.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(81889..82380)
                     /locus_tag="LP245_000173"
     CDS             complement(81889..82380)
                     /locus_tag="LP245_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBL1518122.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            82567..83487
                     /locus_tag="LP245_000174"
     CDS             82567..83487
                     /locus_tag="LP245_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1518123.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            83641..83985
                     /locus_tag="LP245_000175"
     CDS             83641..83985
                     /locus_tag="LP245_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBL1518124.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(84175..84675)
                     /locus_tag="LP245_000176"
     CDS             complement(84175..84675)
                     /locus_tag="LP245_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1518125.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            85203..85286
                     /locus_tag="LP245_000177"
     tRNA            85203..85286
                     /locus_tag="LP245_000177"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:85237..85239,aa:Leu,seq:cag)
     gene            complement(85610..86248)
                     /locus_tag="LP245_000178"
     CDS             complement(85610..86248)
                     /locus_tag="LP245_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1518126.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            86583..87017
                     /locus_tag="LP245_000179"
     CDS             86583..87017
                     /locus_tag="LP245_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL1518127.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            87040..87360
                     /locus_tag="LP245_000180"
     CDS             87040..87360
                     /locus_tag="LP245_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518128.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            87501..87692
                     /locus_tag="LP245_000181"
     CDS             87501..87692
                     /locus_tag="LP245_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518129.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(87763..88020)
                     /locus_tag="LP245_000182"
     CDS             complement(87763..88020)
                     /locus_tag="LP245_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBL1518130.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            88178..88441
                     /locus_tag="LP245_000183"
     CDS             88178..88441
                     /locus_tag="LP245_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518131.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            88465..88653
                     /locus_tag="LP245_000184"
     CDS             88465..88653
                     /locus_tag="LP245_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518132.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(88736..88921)
                     /locus_tag="LP245_000185"
     CDS             complement(88736..88921)
                     /locus_tag="LP245_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518133.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            89136..89507
                     /locus_tag="LP245_000186"
     CDS             89136..89507
                     /locus_tag="LP245_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL1518134.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(89657..89729)
                     /locus_tag="LP245_000187"
     tRNA            complement(89657..89729)
                     /locus_tag="LP245_000187"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(89694..89696),aa:Gln,seq:ctg)
     gene            complement(89775..90203)
                     /locus_tag="LP245_000188"
     CDS             complement(89775..90203)
                     /locus_tag="LP245_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518135.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(90263..91021)
                     /locus_tag="LP245_000189"
     CDS             complement(90263..91021)
                     /locus_tag="LP245_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBL1518136.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            91316..91513
                     /locus_tag="LP245_000190"
     CDS             91316..91513
                     /locus_tag="LP245_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518137.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            91619..92101
                     /locus_tag="LP245_000191"
     CDS             91619..92101
                     /locus_tag="LP245_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518138.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(92159..92755)
                     /locus_tag="LP245_000192"
     CDS             complement(92159..92755)
                     /locus_tag="LP245_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL1518139.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            93142..94608
                     /locus_tag="LP245_000193"
     CDS             93142..94608
                     /locus_tag="LP245_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBL1518140.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT        30713 a        16255 c        20144 g        27545 t
ORIGIN      
        1 ataatttaag ttaaccttaa aactaaactt cttaagtttg gttttaaggt tttttttgtg
       61 ttctagtaaa aatcacttta cataagtttc aaaagtttct ttaatttcct attgttcaat
      121 aagtaacaat gtaaagataa aattaaaaat gttaatacgt attagcaaaa taaaagcttt
      181 tttttattgt gaataaatga acataattag gaggagaaag atgaacttat ttgacatttt
      241 tcgatcgact ttgacagata tgtcgattgt cagtgcaatc acttcaacag tttttattat
      301 attattaggg tttgtttgta gaaaaaaggg gattttttct gaatctgttg gaaaaattct
      361 atcgaaagtc gtcttaacag tggctttgcc agcactggca tttcgagctt tcatgcaaga
      421 tatcaataca gaattactga tgcaaggaat caatgtcttg atttggggat tagttattta
      481 tattattctt attctagttt caaaaccttt tttcttaagc tataaagggg ataagcaaac
      541 aacgttgcgt gtcctgacga tctttggttc tacgaccttt ttcggaacgc ctatcgtcag
      601 tgcgatttat ggtcctgtcg gcgtgatgta ttcctcaatt ttcaatattg gctaccgaat
      661 ctttttgtat tcttatggat acataaaaat gagtggcttg aagatggaag ctaaaaatat
      721 caaagcgatg ttcgtcaatc caatcattat cgctactttt gccggccttt tcatttggct
      781 gttccaaggg tatctgccac aagtgtcagt tacaggtgca gaaggagaga taagccaagt
      841 agcgtttttg cgaattgacc agactgcacc gtggctattt cagccgatgg attatttagc
      901 tggtttaagt tcaccattgg cgtggctagc aatcggcgca acattaggtg aagtaagctt
      961 caaaaaagct gcatctgaaa aaacttcatg gtattacagt ctagtcaaag tggtatttgt
     1021 acctgcattg aatatcgtga ttctagcagt tttgacggca acgaatattc taccagtcaa
     1081 ttttgaagca ctggcaacaa tcgttatcat gatggctaca ccagctgcaa cagtggcagc
     1141 agcctatgct atcagttttg atagggaggc acttttagcc tccaatgcat ccttactgtc
     1201 aactattttt gctgtggtac tgacacctgt atggatcgtt gtattacaaa tgattcatgg
     1261 cataggttta ttttcataag aaatggagga agaaagtatg agaatcgcat gttacggtgt
     1321 tcgtccgaac gagatagatt tttttgaaaa attgaatatt taccattatg atctcagtct
     1381 ttatgaagaa ctgttgacac atgacaatat cgtgtcagca aaggaccatg atgctgtatt
     1441 gttgagggga aattgtatag cagatgagac caatcttgca aaaatgcagg aatatgggat
     1501 tcgttatgtt tttacacgga ctgtgggagt caatcatatc gatctacaag cggcagctga
     1561 ttttggtatg acagtagccc gtgtaccatc gtattcgcca aatgcgatag cagagttatc
     1621 tttgactttt gccatgatgc ttttgagaaa tactgcgtat acgacgatcc gaacatcttt
     1681 caaagatttt cgagtggatg agcaaatgtt tagtcgtgaa atcagaaatt gcacagtagg
     1741 gatcatagga acaggcagga tagggttgac ggaagctgtt ttgtttaagg gactaggagc
     1801 caaagtgatc ggctacgata ttcatcagac agaagctgct aaaaaagtat tgacgttcca
     1861 ctcgcttgaa gagttattag ccaaaagcga tattgtcagt attcatgtac ctcatatccc
     1921 aggtgaaaac gatcaaatga tcaatgaagg atttttagct caaatgaaaa aaggtagcat
     1981 cttgattaat acagcccgtg gagagcttca agataatgaa gctattttaa gagctttgaa
     2041 aagcaatcat ttagctggtt ttgcaaccga tgtttttgca aatgaaacag aggttttttt
     2101 ccgatccttc aagccatggg agacgattcc agaccctgct atccagcaat tagtagaaat
     2161 gtaccctaga gttcttgtaa ccccgcatgt aggttcaaat acagatgagg cattatcaaa
     2221 tatgatttcg acaagtttcg agaactttcg tgaaataata gaaactggaa aaacgaaaaa
     2281 tgaggtatct cttcctaaag cccgtcaatt aagataagaa aacatggata ttcgtcaata
     2341 aaatgtttaa aaatagtcca agtaaacagt tgttacttct gtatacttgg actattttgt
     2401 atgggataat tcgatgactc aacagtaatc tgtgagcttt ttccgcccat tctttgtcaa
     2461 ttcataacag gttagcggcc ggccgatttc caaatatttg attctttcgt tcaatatatc
     2521 ttgttctact aaaaaattca aatatttctt gacggatata cgtgacagtg agcttttttg
     2581 agccagttct tttgttgaaa aaatagtatc ttcttttaga ataaatgcac ttattttttt
     2641 taaagtcagt tttgacagac ctttaggcaa atcgatgaat gatggtattt cgtgaatggg
     2701 agtggtgtgg ttgaatactt gatcgatcaa tttctgatcg gctttttcag tcgtttggat
     2761 tgtctgagag aaagcaagat acttttcgat cgccagctga aaacgttgca aagtgaacgg
     2821 tttgatcaaa taatctaagg caccgtagcg gatcacattc tttatggttt cgatatcatc
     2881 tgcagcagtg atcaaaatca ctgggatatc atttccttgc tgtctaagcc aagataaaaa
     2941 atggatacca ctttcgccag gcatgtatac atcaagcagc agcagatctg cgtttttttg
     3001 tctgaaatat ttttttcctt cttctacatt tctgaaactt tcgattacgt tcatattagg
     3061 gatgctttcc acaaaagtac gattcaattc tgcaaccatt ggatcatctt cgattatcag
     3121 gacatttgtc atcattttga tcttcctttt ttggtaattc tagatagacg attgtaccgc
     3181 catttgtttg tttggaaaat tctaaaaatc caccgtggcg tttgacgatt gaatggatga
     3241 gattcaatcc aaacccacga ttgattccct tcgtcgaaaa acctagcgta aatatttttt
     3301 ctgagatttc ttctgatatc ccgacaccgt catcgcagac ggtcacgatg aatacttcag
     3361 cttctgtgtc atagtttaaa tgaatccgga cctgtccgtt tctttcatgt ttttgtagca
     3421 cggcttcttt tgcattatca agtaagttcc ctaacacttg caaaagtgaa tggatggagt
     3481 catccatctc cattttaggg ataaaagaat cgctttctaa cagcatttca acagattgtt
     3541 ctttggcttc gtttattttg cctaataaaa aaccggcaat tgcaggtact ttgatcagac
     3601 ttgagacttg gccaatctct tttttataat tttgatttag ctgctggata aaatgggtga
     3661 cttcttcata cttcttcaaa tcaatcaaac cagaaatgac atgaagttta ttcatgaatt
     3721 catgggtttg agctctcatg gagtttatat attgtttcgt ccccccaagc tcctccatta
     3781 atttcattac ttctgatcga tttcgtaaag ttgcgactgc tcctaaaaaa cggtcattgc
     3841 taaaaagagg tgtaacgcta gaaatagttt ctatcccatt taaatacatg gattgagtcc
     3901 gaacggtcgt ttgatgctca atcgtctctt taaacaaaac gtcatataga ttatcactga
     3961 tttttttcct acttcgaaat ccaatagctg ctctgtttgg tagaaaatgt tttttgcagg
     4021 tgtattgatc aagaggatag ttttatcaga agagatggct aagattcctt catctacttc
     4081 attttcgata atcgtttttt cacttaactg ttctgctatt tcttgtggtt caagtccaag
     4141 cagtactttt ttcatttttt gggcaagaaa aacggcgcct atgatgccta cgctaagtcc
     4201 aataatcaat gaaaaaacaa tcattttttg tccatctttg acttgattgt caatcgtgtt
     4261 gtttgttaag ccaacacaaa ctgcaccaat aatctcttga tcataataaa tagggacgaa
     4321 atagcggaag ccgaacccta acattccttc tttttcagag aaaaattctt gtcctccaat
     4381 cacttttttc acatcttcat gacttgagaa aggaagaccg atgtaacttg ggtctgcgtg
     4441 agaatatcga atgccttcag ggtccatgac aacgataaaa tctaaattcg atgcaatcat
     4501 gatttcattt gttattcctt gaatcgcatg tgtcgggtca ccagtctgca gctttttttg
     4561 gatgagttta tcattggcaa cgattttagc aatgctagag attttatctg acacactaga
     4621 tcggttcatc gaaagaataa aattcctgat caatatggca gaaacaatca aagaaacgaa
     4681 tgtggagaaa caaacgacaa ggatgatcgt gttctggagc tttaatggtt ttttcttaaa
     4741 aaaaggaaac ataggctacc tcgaaagaat ttattgtgaa aattttaaca tgaaaacaaa
     4801 aatttaacaa attgtcaacg ataaacacaa ccttcctata aaaaacacca ctgagtcggt
     4861 aaaagaagct atacagaatt ttcaaacatt ggtatgatag acgtagaaat ggaaggaggc
     4921 gtgtatatga tagggggaat cgcacttgag acgatttatt ggtatacatt gctgatttgt
     4981 gcaggattgg cagtcctatt gattattttt ggagatgtat tcgattttga tggcccgctt
     5041 gatccgatgc ttattatccc ttggttaact ttcacaagct tatttggttt tctaggtgag
     5101 cgtttaacag atcaatcatc tttattttta tttattgcta gtggaggcat atcgatagtg
     5161 ttggtatttt tgcttaattt ctatatattg atgccgatga aacatgccga atcaacgatg
     5221 tcgtcttctg aaaaaactct ggaaggacaa gtagctgttg tgatcacacc gatccctgta
     5281 cgaggtatgg gagaaattca gttgaaaagt gttaccggtt ccattagtcg tccagcttgt
     5341 ttttacagcc cccaagaaca gacagctgag cggggaacga aagtattgat cattgagatc
     5401 aaggaaagaa tctgttatgt catgccttat gaaagcatga taaaagctta aaggagcgtg
     5461 tgttaaatgg aaataccagt tgtttttatc gcgatcgcaa tcgcagcttt gattttactg
     5521 atgttgctga tcgtctttgt agcgaagtac cagacagcaa aaccggatga agcgttgatc
     5581 atcagtggaa gttatttagg aagcaaaaat gtgcacattg atgaaagcaa taacaaaatc
     5641 aaaattgtgc gtggaggtgg cgcattcgtc ttgccagttt ttcaacgttc gaatcggatc
     5701 agtctattat cgagtaaatt ggacgtctcc acccctgaag tgtatacgga acaaggcgta
     5761 ccggtgatgt gtgatggtac ttcgatcatc aaaatcggtt catctgtaga agagattgct
     5821 acagcagcag aacagttttt aggcaagaca agagaagaac tggaaaatga agcaagagaa
     5881 gtattagaag gacacttgcg ctcgattctt ggttctatga ctgtagaaga aatctatcaa
     5941 aatcgcgata agttcagtca aagcgtacaa gaagtcgctt ctgtagacct tgcaaaaatg
     6001 gggttgatca tcgtttcttt cactatcaaa gaggtcagag acaaaaacgg ttatcttgac
     6061 tctttaggga aaccaagaat cgcccaagtc aaaagagatg cagatatagc agaagcggaa
     6121 gctctaaaag aaacgcgtat caaaaaagct caagcagaaa aagaatcaca agcagctgaa
     6181 ttacagcgac aaacagagat cgcagaatca ttaaaagaaa aagaactgaa attagcaacc
     6241 tacaaacaag aacaagatgt tgctaaagca aaagcagacc aagcctacaa tttagaaagt
     6301 gcccgagcac aacaacaagt aatcgaacag gaaatgcaga ttaaaatcgt agaacgtcaa
     6361 aaacaaatcg aactggaaga aaaagaaatc acacgtcgtg aaaagcaata tgattcggaa
     6421 gtgaagaaaa aagcagatgc cgatcggtac gctaaagaac aagaagcaca agctcaaaaa
     6481 gtcaaagaag tgactgaagc cgaagcagaa cgattccgtg aggaagcact ggcagaagcg
     6541 gaagccaata agacacgttt agctggacaa gcagaagccg aagcagcact agcaaaagga
     6601 aaagcagaag ccgaagcaaa acaaaagatc gccaatgcct tcaaggaata tggcgaagca
     6661 gctgtcttga gtatggttat cgatatgcta ccgcaattga tgcgcgaagc agcacagccg
     6721 ctaggaaata tcgaaaaaat ctctgttgtc gatacaggaa gcagttcagg agaaaccagt
     6781 ggagcgaacc gagtgacaaa ttatgccaca aatttgcttt cttctactca agaaacacta
     6841 aaagcgacaa caggacttga cttgaaggaa atcgtagaga atttgtcgac acgtgggact
     6901 actagccaag taaatatgta tgaagcgcca aaagaggcag aacaaaactc gatgaaggaa
     6961 gaataaagta gtacacttca ccgttcaatc aaaaatggag gaagactttt taaagttctt
     7021 ctctccattt ttttatttta ttgcaaaaga aaattagtcc tcgctatttt tcttttgttt
     7081 ttggatctta gcttctatct cttgtaaatt tgttcttagc aatcgttctt tcttttggag
     7141 ttcgaccaaa tcttctgata gttcttcctt cttttctgtt tcaggaggac gaagaaagaa
     7201 attgataccg attgcaatga atgtccctat aaaagtatct agtacacgtt ggatagcata
     7261 caaagcggat tcgccttgag ggatgctcaa cgcaatcagc aacaacgtag ctattgcgga
     7321 aatgataccg gaattattgt taataccatc tgacacgacg atcacaataa taactagaat
     7381 aggaagcaag atcaattcta ccaaaaaatc attgtgaaaa tagcttttga caaaaaaata
     7441 aatgatagct aatgtaccac ctaatgtatt gccgatgatc ctagactttc caaaagaaac
     7501 ggttgtagtc aagtcctgac gcaaagaaaa aacagcagat aatgcagcaa tcatcgggat
     7561 tcctcgttga gtcaaatgaa aaaacaagat acataaaaaa acagctaagg cacttttgat
     7621 cgtacgcata cctagtcgaa aacggccaaa ttgcatagag attctccttt ttggtctttt
     7681 tactatcata cctaaacttt tgtctgatag ctagtttttc attattcaag tataattaaa
     7741 ataaaaaagg gggaagtaaa tgcgtatagg aatgcgaaca gtcaaaacag tgatcagtgt
     7801 cttcttttcg atggtcacag cgggtagctt atcgctgttg tattggccag ctgcagggat
     7861 cattgcatta ttaagtgtag gaaataccaa gcgctctaca ttgcgtacgg gcatgaatcg
     7921 aatcgcagcc tttatattag ctacggcaac agcactgttc agtttttttg ctgttgggta
     7981 tactattttt ggcttcagtc tttttttatt cctgttcatc ccgcttgcct ctcgcttcaa
     8041 attaaccgaa gggatagtag taaattcggt tttggtcact cattatttag tggaggaaaa
     8101 catgtcttgg cagctgatcg gcaatgaagc gggattaatg gcgattggat tagtatttgc
     8161 tttgcttgca aatgtttaca tgccagatcg tacgaagcag ctgaaggaaa accaaataca
     8221 gatcgaaaaa gaatttcgaa atattttgag acaaatggca gaatttcttt tatcagaaaa
     8281 taaagaagat gtgcagatca aatgcgaaca tttactgaca ttcattcgcg aaagccaaga
     8341 agatgccaga gaacatcaag aaaactactg gctcagacag ccgctatact acgaaactta
     8401 cttctctatg agaagagcac aggccaatgt gattaaagac atgctggaaa atctagagag
     8461 aatccagcaa ccagcttatt atggaaaaca tatctatggt ttattgattt atactgcaga
     8521 aacattttca gagtcaaatg atggcagaca aattttaaca cgtattgaag aagtttatgt
     8581 attgtatcgg caaatgcctc tgccgactag tcgccctgaa ttcgaggatc gagcagaatt
     8641 gttccagttt ttgcagtctt ttaaaagttt tattgaaatc aaggcagaat tctcccaaca
     8701 aaaaatccaa aaatagaggt tgtgaattca gctaatattc aggtcaaaaa gctgatttca
     8761 caacctcttc tttaaacggt gttctcctgt caactcctcg gtcacaagtc acaatattca
     8821 acaaacatga gaagctgttt tttgaaattg ctccttgtga ctcggagctg aacggtaggc
     8881 tcacaacctc tttcttaaac ggtgttcaaa agctttcctc tgcggtaata agtccagcca
     8941 aacgaaaaat aggaggagct atttttgttt ggctgttctt attacttgat gcagaacagc
     9001 tttttcacaa ccttttaaaa ttacatattt ttccatagaa cttgcatttg atccaagatt
     9061 tcgatgacat cttttgtcaa gaagagagag cgattgggca agtcaccttc aatcatgtgt
     9121 accatattct ttatttcgta attcattgct tcagatgtat tcccgctttc gatgaattcc
     9181 tttgtaccat ctgtaaataa gatctccgca cgatcagcac gcgggtaatc agcaatcgtc
     9241 acataaccgt tctcaaaggc aacgataccg acttttggca tttttgcctg aaaagtcaag
     9301 ctgacagcag caagttcatt ttctttgtta cgcaagatag tgacggattg ttcgtccacg
     9361 cctgtttcaa aaggaaccat tgtagaggca actacttcag gttgagagct caaaaagaaa
     9421 cgagcgaaag atacagcata cgtaccgata tccaacagag ctcctccagc taattctgga
     9481 ttgaagaacc ggtttttagg gtctggttct ttgtaactgc cgaaaggtgc ttggatcatt
     9541 tttaaagccc ccagttttcc tgtatccatt attgagcgta actgctgata aagtggcatg
     9601 ttgaagattg tcatcgcttc tgctaagatc aaattctttt cttctgctaa gcgcatagcg
     9661 tcagccagtt cttttttatt catcgtgatg gctttttcac atagaacgtg tttgcctgct
     9721 tccaatgctg ccaagatatg gtcgatatgc tgtctatttg gtacagcaat gtacacgatg
     9781 tcgatttcag catcgtctaa catttcttga tagcttccgt aagcttttgg aatattgtaa
     9841 cggtgagcga agttttccgc tttttctgaa gttctggaag caactgctgt tagttcgctc
     9901 gtctcttgat tgaagctttc ggcaaactca tgtgcgatgg taccaagacc aacgattccc
     9961 cattgatatt ttttcatctg aaaacgctcc ttcatagttg gattgagttt cttgtctgtc
    10021 tattattata acaaaaatca cgaagaataa agaggagagg acttgaaaca ttaaaaaaaa
    10081 tgaaagcagc gatttaagag gtgctttttg atcaaaactt aagtagaata gttaaaagga
    10141 ggggataaac gtgcatcaag tatatattga tcttattatg agtgtattat tagaacagtt
    10201 tgaaactgaa aaaaattttt tagatgaata cttgctgatc agtccagaac aatggcaaaa
    10261 atggaaagat ggcgagaaaa atctgccatc tgaagcgatg cagaaagtaa aaaatctttt
    10321 cactgattat gaatggatgc taacgcaaaa gattttgcgt caaacgatta tttttcccga
    10381 aaaacgaaac gttgccgttg cagagtacaa gcaaatcaaa acacgcatcg cgcaaaaatg
    10441 gcttagcagc aaagcagcaa aagtcgagct gatccctttg aaaaataatc agcaggctgg
    10501 tagatacctt gacttgaaag taagtattca atatgatgaa tggggctatg atgatatttt
    10561 gaattttcgt ctgccagcag atgttcaaaa acagatcgaa ggagaaaaaa tcgaacttct
    10621 cgattgggtg aatgaaaatc tggaagaaac ttacgttcat gaggcgaatg gggaacgtga
    10681 agaacaacga aaggattttt caagtgaata aatttttagg atttggagca gttgtgatta
    10741 tgatcgcagc aatgggctat gttattttta gcgatgatga ttcgcatgtt caagccggca
    10801 atcaagcagt cgaacgaaca agcaccaaaa caactgctag taaagaaaag aacagtcaaa
    10861 caaccagcag caaggtaaag gacaaagaaa caaaagatcg tacgtccaaa caattgccag
    10921 atgttaaaac agacgattgg aagctagttt tggttggtcc agatcacaaa ttagaaaaag
    10981 aaattgatga gtctactcaa ttggcatcat taagtaacgg atacttgatc gacaaacgca
    11041 ttgctccaga atatgaagca tttgccaagg ctgctgaagc agctggattt ccattagtga
    11101 tggtctcagc ttaccggtct gtatcatccc aacaacaagt tttcgaacaa aatgtccaag
    11161 atgtgatgag tcgtcaaggt gtatcagaag aggaggcgac aaagattact aaagaaacga
    11221 ttacggagcc aggatacagc gaacaccaca caggtctggc agtcgatgtc gtcgatcaaa
    11281 actggtacaa cagttatcct tctactgtat tggatgcaag ttacggagat cagcctggag
    11341 ctaaatggat cgcagataat gctgcgcagt atggatttat cgttcgttat ccaaaaggac
    11401 acgaagatat aactaagatc acatatgaac cttggcactt acgttatgtc ggtaaagaaa
    11461 acgctgagta tatcaccaaa caccaattga cgctagaaga atatctgaat gaattaaatg
    11521 aaaagtagga attgatcatg gcgaaaaaaa agtggaaaaa gcaaaagcgc aagaatatcc
    11581 gttggccagc agtggttgcc ggtgtagcag tgatactctt agcctttgtt ttttccttga
    11641 agaatctgtc ttctcctttt actgataatc agcaagaaaa tgaagcgcaa tcccatcagc
    11701 aatttattga acggcttgtt ccgcatgccc aagaactaca agatggttat ggagtgcttc
    11761 ctagtatcat tttaggacaa gctatattag aatcaaattg gggaaaaagt accttggcta
    11821 gcaaatacaa taatcttttc gggatcaagg cttatgggga tcagaagaaa gtaagcctgg
    11881 aaacaaagga atttgttaac gaagaatgga taactatcca aggagacttc aaagtgtatg
    11941 attcatggga acagtccatg gatgaccata cacaactgtt cgtccaagga gtagattgga
    12001 atcctgcgct gtatgaaaaa gtgattacgg ccaccaacta tcaggaagcc gcacaagcat
    12061 tgcaagatgc aggttatgcg acagaccccg gttatgcgca aaaaatcatc caggtcatcg
    12121 agacgtatca attgaatcag tatgaccgga gatagcaaag gagaagtggc tgatggcaga
    12181 acaatttacg ccagaaatca tgacggaatt gagaaaagat atcgtaagag taccggaaat
    12241 cattttagaa gcaagcggga tcaagatatt tggaaaattg atccgttcga tcatctttac
    12301 tacggatatt gcgatcatac gtaatacaaa tgcgaatgca gtaattgctg tgtatccttt
    12361 tacacctcat ccagcgatta ctaaaagcat tattgaggca gctgacattc cagttttctc
    12421 cggtgtaggt ggtggtttga cacaaggtgc tcgttcttcc tacatgagca tgttcgcaga
    12481 agcgcaaggt tcgttagggg tcgttttgaa cggtcctacg cctttagaga cagtaaaaga
    12541 agtttgtcga gtagttgata ttccagttat cagtacggta acgtcgaaat atacagaaat
    12601 agatgaaaag ttagcagctg gtatttcgat tatcaatatc agtgcaggta aagaaactgc
    12661 agaagcagta cgccattttc gtaaaaaata tcctgaactt cctatcattg cgacaggtgg
    12721 tccaacggaa gaaagtattg ctgagaccat tcaagcagga gcaaatgcca tcacatatac
    12781 gccaccaagt agcggagagc tttttagtcg taaaatggaa aaatatcggg aaactgagaa
    12841 aaagaatcat gaataacagg tgagaatcaa aagacgagga agagcagata gtggctcttc
    12901 ctcgtctttt gtactccagt actatttgtt cagaattcaa aaaaaagaga aatttttttg
    12961 tttttttacc tgtaatgtac ataagaagag ttaaaacctt ttgttattat tagcattcta
    13021 acaaaaaaat gtcttgattt attgaagcgc tttctataga atgaaaaacg aataaaaact
    13081 aaaaaaggca cccgacaatt tagtagcagc taaattgtcg gggcttgaaa agtcagcggg
    13141 aactgaccaa tcaagttgcc atagtcaatg cttgtgcatc gacgtgtata ttgtacctaa
    13201 tttcatacag aattactagt tatttttctg ttttttaggg aagagcgcac acgaagaagc
    13261 atgcttattt agctatgtca aggatattgg gcagttgtct gatatccttt tttctttgcg
    13321 taattatcct cccatcattg aagcaagaag tgtttttagc gatgaaagaa gaatcagcac
    13381 tatctaattt ttcttgaaag tattgagttg ttcatcctag gcagaacgat aaggcaagtc
    13441 ttggttttta ttccccttga aaaagatcgt ttaataaata tgttctgtat aaaaatacag
    13501 tatattgaaa aataacaatg gaagtagagg tgcagagaat gaagaaaaga atgagaatca
    13561 tcttagcttt aagtgttatg ttattcttct tgacggcttg tgggcaagaa gatgacaaaa
    13621 aaatcacgct gaacatggct tggtggggtt cgcaagtccg acacgatgca acagtaaaag
    13681 taatcgagct ttatgaagaa aaaaatcccc atgtgacgat cgattatgaa ttttatgatt
    13741 atgaaggata ttacacaaaa ttaggtacac tagcagcatc agatgatatc tgggacattt
    13801 tccaactgaa caatcaattt cctcaataca tcaatcagat tgaaccatta gatgaatatg
    13861 tggagcaagg gataattgat atttctaatg cagatgaatc ctatttagca acgacgactt
    13921 acgacgggca attagttgga ctgtctaacg gggtgaattc gtttgcgatt gcttacaata
    13981 aaaatatatt tgaacaatta aatatccctg aaccagcttc aaattggaca tgggatgaat
    14041 ttgaacaaat cagctatcaa atcactgaag aattaggaat ctatgctatt tcaagattcg
    14101 aagattttat agctggctgt attattcaaa taccacaagt tgagaaagga ttgaattttt
    14161 ataatcggga agatctatct aacagcttgg gatttgaaaa tccagactat ctaacagatt
    14221 ttttccagct gcgtaaaaat ctggtagaca aaggggccca tccagaacca ggtggtggag
    14281 ctgcaagtac gacggatctg tcttttcagg cggttaggga tagagaagcg gcaatggtgt
    14341 ttctatcaag taaccagttg acagaaatat tgtcaggggc tcctgaagat atggagattc
    14401 agttgattaa tccacctcgc agaaaagcag atggagaatc tggtatccct ttacgttctt
    14461 cgcaaatgct gagtatggca aaaagctcag cccataaaga agaagctgct aagtttattg
    14521 atttctttca aaacagtgaa gaagccaatg aaattttaaa aggagaacgt ggtgtaccaa
    14581 tcatgtcgaa tattcgagaa cagctcgctc gtgcagatga tgcaactttg caagcgacat
    14641 ttgattattt agaaatgatt tccgatatgg acaacggcga agtgaatgtc tttgatagtg
    14701 ctttgaatcc ggaaattcaa gaccaataca atcttttagt tgaaaaagtc atttatgaag
    14761 aagtaacagc agaagaagca gcagagagtc tttatgagtt tgcgtcaaac attctaggat
    14821 agcagcagga ggaaggcatg aaaaaagaaa aactaaaacg gttcttggat caagacaatg
    14881 tggtcggtta cgtatttgct tctccattca tcctaggatt tctattgata acagtgatac
    14941 cgatgatctt gtcactttat tattcgttca ccgattatcg tttgggaaat ccagtctcat
    15001 ggatcggctt ggataattat ataaagatgc tgagtgatgc ccgttttttg aactccatcc
    15061 gagtcacttt tctctatgta tttgcatctg tacctgtgaa actgatcttt ggtctattga
    15121 ttgcttatct tttaacgagg aatatcaaag gaacgacttt ctttcgttct ttgtattatg
    15181 tgcctagttt gatcggtggc agtatttcta tcgctctagt ttggcgggag ttgttttcta
    15241 aaaacgggtt agtgaatatt ttcctggaac gattaggcgc acctgcgctt tcctggttta
    15301 gcgatcaaaa actggtcatg atccctcttg ttttgatgtc tgcttggcaa ttcggttcgg
    15361 caatgatcat ctttgctgca ggtatcaaag agatcccagg ctcgtattat gaagcggcag
    15421 agatcgatgg agcgaacaaa tggcagacgt tttacaagat cacgttacct cttctttcgc
    15481 cgatcatttt gtataacttg gttatgcaga caatcgcggc gtttatgact tttacgcagg
    15541 catttatcat tacccaaggt ggtccgaatg atgccacgaa cttttatgct ctttatgtgt
    15601 ataaccaagc tttttctttt aattctatgg ggtatgctag tgctatttcg tggatcatgc
    15661 tgttgattat gggagctgtc acctttctga ttttcaaatc atcaaaaaaa tgggtcgttg
    15721 tgtgaatgag aggaggaaga aatgaataat acagtaacga aatggtttca atacggtttt
    15781 attttgctat taggtctagt catgatttat ccggtcttat ggatgatcgc aggttctttt
    15841 aaaacggatc aagagattat gagtggttcg ctgaatttga ttccagagac ttttcaatgg
    15901 gaaaattacg caaaaggatg ggcggggttt gctggaattt cattttttac tttctttagg
    15961 aattcgtttg tcatctctgc agtttcgacg atagggacag ttctgagctc gacttgtatt
    16021 gcttacgcat tatcgagaat cgatttcaaa ggaaaaagat tctggttcgt cgtcatgtta
    16081 gtaacgatga tgattcctgc acaagtgatt ttgattccgc agtttattat ttacaatcgg
    16141 ctgaatttgg ttgggacgta tgtgccgctg attttaccac atttttttgg acaagcattt
    16201 ttcatttacc agatcatgca attcatggtc agcatcccca aagagttaga tgaatcagcg
    16261 attattgacg gatgcagcaa gtatagtgtc tttaccaaaa ttatttttcc tttgctgaaa
    16321 ccttcgatca tcacgacgat catcatccag ttttattgga aatgggacga cttcatggga
    16381 ccattgattt atttaaacaa gccgagatct tacacggtat cgattgccat caaattattt
    16441 gcagacgctg gatctagtac gacttacgcg agtatgtttg cgatgtctac gttgtcgctg
    16501 ctaccggttt ttctgatttt cttattcttc aataaatatc ttgtccaggg gatcagtaca
    16561 agcggtctga agggctgaat atgaaaaagc caatagaaga gatgtttctt tacaagctca
    16621 actactatgt ctgtcggatt tttttaacca gtcttatcag taatgctctt ttcgctttag
    16681 ttctaggatg tttgttcact ttaggattag tgctgtctgc tcgtgttgtc tatctgattt
    16741 attttttgat gatgtatcct tcttattatc tatctgtcca ttacttggca gaaaaaaagg
    16801 tatgttggag gaaaggaaaa atcaaacgga tgtgtttcat cattacgttg tttcagctgt
    16861 ttgtcattat ttttgcagtt gattggtatt tattagtggg aaagattgga gcttggtatc
    16921 tgattccttt tctattgtgt ctgttgcttt ttgtatccca tagttttttt agtacgctaa
    16981 ttgatatctg caaagaagat aaagcagata gtcttgttta tttgatcaaa aggaatatct
    17041 ggctgttgtc aaaaaacgtc aaggggtttc tgtggtattt atgccttttg tatggactgt
    17101 tctggtgtat acagcatgat tttttactca ctgcattact gtatccaggg ctgccatttg
    17161 tcacagtatt ttgcttaaaa gaaaaggaga atgactttaa atgaagaaaa aatatgtaca
    17221 agtcggactt ggtgggagag cgcgtttttt ttatgaggca attgcctcta cgtatcatca
    17281 aacttgtgaa ctagtcggtt tttgtgatgt atctcaaaca aggatggatt atgcaaatcg
    17341 gatacttgtg aacaagtatg gacagaaaaa agtaaagaca tgtatgccat cacaatttga
    17401 gcaactactg gatgacgtac ggccggctga agtcattatt acgtcagtag atcgaacgca
    17461 tcatgattat atcattcgtg caatgaaaaa aggatatgat gttatttgcg aaaaacctct
    17521 gactatcgat gaggaaaaag ctcaagaaat aataacggtc caaaaacaga cgggaagaag
    17581 cctgcgagtc acttttaatt atcgttatgc accgtatcac acgaagataa aggaactgat
    17641 agaaagtgat gtgattggtg atgtgttttc tatccacttc gaatggctgt taaatacgca
    17701 acacggggca gattatttca gaagatgcat cgaaataagc acaatagcgg cgggcttctt
    17761 gttcataaat ctacccatca ttttgatcta gtgaattttt ggttgaacag ccgtccccaa
    17821 aaggtatttg cattcggtgg attaaacttt tatgggatgc ataatgcgga gaaacgcgga
    17881 gtagaaatat tttacagtcg atgctatgga agcgaactag ctaaagctga tccatttgct
    17941 atagacctgt cagccaatga ggaattgcga gaaatgtatt tagaagcaga aaaagacagt
    18001 ggatatattc gtgaccgcag tgtattttcc gatgatatct ctattgaaga tacactaggc
    18061 gtaacggtca aatatgaaac tggtgcgatt ttgacgtatt cgctaaacgc gtatatgccg
    18121 tgggaaggat tcaatgtttc tttcaatggc agcaaaggac ggatcgaaat gaaagtgatc
    18181 gaaaagtctt acatcaatgc aggtggagat aaaaaggatg aaggagcagc cgttcttcag
    18241 tccatccatg tctatccgat gttcggtgag ccatatgagg taatcgtcga acaagaagcg
    18301 ggcggacatg gcggaggaga tccgcgttta ttagatgatc tatttggtga agaaaaagaa
    18361 gaagatccgt ggaatcgggc agcaactcac gtagatggta ttttgtcgat tttgacagga
    18421 atcgcagcaa atcattctat tgcttcagga aaagcagtag tgattgacga gcttgtcagc
    18481 ttaaaagaat aagaatagat ttacggaaat tacttcccgt agtttataaa atcttgcctt
    18541 attgccgata ggctgtcttt tgaacactat ttattcggaa aaaggggcta tgacatgctt
    18601 tttgtcatgc cttcttttta tgtgggctgc ttttttagat aggagaaaat aaaaataact
    18661 atttaaaccc gaacaaaaag gaataatgca ttaaaaatca ttagatttta caaaaaaata
    18721 agtaaaccac gttgtcagtt tcagaaagta gtgttagact gttttcaata tttgaaacaa
    18781 cattttttat tcaaatatgg caaactgcct tcacgtgcaa aacagttgca agaaaatgaa
    18841 tttacactat tattagtttt acatacctac ttatatatcg tcataatatg gatgacagtt
    18901 tctagccagt accgtaaatg ctggactata agtaaaagat tggctatttc acccttcttt
    18961 tcttatgata aagtggaggg tgtttttctt taacagaaac atagtaggtt tttgcacaaa
    19021 agcggttatt tcggtattaa taaatgataa aggagcaaat aaagtgaaag aattagttga
    19081 acgtattcaa aaagacggac gtatattagg cgagggcgta ttaaaagtcg acagcttcgt
    19141 cactcaccaa gtagaccctg tattgatgga acaaatggga aaacggtttg cagaagtatt
    19201 taaagaacaa ggaatcacga aagttgtgac cattgaagct tctgggatcg caccagcttt
    19261 atttgctgca agagaattag atgttccaat gatcttcgct agaaaagcaa aaagtttgac
    19321 gatggatgaa gaattattga cagcttctgt ttattctttt acgaaacaag tgacaagtac
    19381 gatttctatt tctcgtaaat ttttatcttc agaagacaaa gtattgatta tcgacgattt
    19441 cttggcaaac ggacaagcgg caaaaggatt gatcgaatta tgccagcaag ctggagcgca
    19501 agtagaagga atcgggatcg tcatcgaaaa gtctttccaa gatggacgtc agttacttga
    19561 agaaatggga ttgagagtcg tttctcttgc gcgtattgct tccttgacga atggacaagt
    19621 tgagtttctt gaggaggacg cataatcgtg gaaaaagaaa cacaaaatgg aaaagctgcg
    19681 gttttagggc tgcagcatct gctagcgatg tatgcaggag cagtagcggt gcctcttttg
    19741 atcggtacag gactaggctt taatcaagaa cagatgactt atttgatttc aattgatatc
    19801 tttatgtgtg gattagcgac attattgcaa ttgacagtta accgattttt cggaattggc
    19861 ttgcctgtcg ttttaggatg tgcgatccaa gcagtagctc cactgatctt gatcggaacc
    19921 aatgaaggag taggagctat ctacggatct attatcgctt ctgggatctt tgttgtgtta
    19981 gtttctggtg tcttttctaa aattaaaaaa ctattccctc ctatagtaac aggaacggtt
    20041 atcaccgtta ttggtttgac tttgattcct gtagcaatcg agaaaatggg tggaggtaat
    20101 gcaacagcag ctgattttgg tgacaaaaca aatctgctac ttgcatttgt gacgattctc
    20161 ctaattgtag gcgtgcaaat gctggcaaaa gggttcattc gttcaatcgc ggtattgatt
    20221 ggtttagtcg gaggaagcat cttagctgct ttcatgggaa tgattgatct gagcgcgatt
    20281 ggagatgcgc cgttgttcca tgttccacaa cccttttatt ttggtaaacc aactttcgac
    20341 gtatggtcga ttttactaat gatcatcatt tccatggtca gcatggtaga atcaacaggt
    20401 gtatattttg cacttggtga cattactggg aaaaatgttg gagaagaaga attgaaaaag
    20461 ggatatcgtg cagaaggact tgccgttatc ttaggcggta ttttcaatac attcccttat
    20521 actggctttt ctcaaaatgt cggattggtt caactttcgg gaatcaaaac aagaaaaccc
    20581 atctatttct ctgcattctt cttgattgtt ttaggattat tccctaaaat cggtgcgtta
    20641 gcacaaatca tccctgagcc ggtacttggt ggaggaatgt tagtcatgtt cgggatggtg
    20701 gcagtccaag gaatccgtat gctgttggaa gttgatttca gcaatgataa aaatctattg
    20761 attgttgctg tttctgttgg atttgggctg ggtttcaatg ttacgccgac attattcagt
    20821 caaatgccgc aaacattgca aatgttcact ggaaatggca tcgtaatgag tagcattacg
    20881 gctatcatat tgaatttgat ctttaatgga ttgaaaaaag atgaagaaat attggaagaa
    20941 gccttcaaga agtaatagag caaaagaaag gttgtgaaat cagcgttttg acctgattgt
    21001 tagagaaaca aacggaaaaa tagttcctcg tattttgccg tttgtttgag ctaataccga
    21061 gggtcagctg attgaacacc gttgaaggaa gaggtcgtga gcctgccgtt catctccgag
    21121 tcacaaggaa caatttcaaa aaaaagcttc tcatgtttgt tgaatattgt tccttgtgac
    21181 cgaggagttg gcaggagaac accgtttatc cataaaaagg aatgtgacct aacttttgtc
    21241 acattccttt tttttatctt taataaacac gaacaataaa atgtttttct ttgttaacat
    21301 tcgaaatttc tttgacatca aaaaaagtga ttgttaaaat atgaatgtag aaaaactggg
    21361 aggaaaaaca atgacagcaa aaatctctgt gattatgggg agtacttcag attgggaaac
    21421 aatgaaagaa gcatgtcaaa tattggatga attcggtgtg tcttatgaaa aaaaggtcgt
    21481 ttctgctcat cgaaccccag atttgatgtt tgaatatgca caaaacgctc gaaaaaaagg
    21541 aatcaaaatc attattgcag gagcaggggg agccgcgcat ctgccgggta tggtcgcatc
    21601 aaaaacaact ttgccggtta tcggtgtacc ggtccaatca cgaacattaa atggtttgga
    21661 ttcgcttctt tcgattgtcc aaatgcctgg aggagtacct gtagctacta cagcaatcgg
    21721 aaaagcggga gcaattaatg ctggactact tgcgatacag atgctttcca tgtatgattt
    21781 agaattggag gctaaattgg ctgaaagacg ttcaatgttg gctaaaactg ttatagaaag
    21841 tagtgatcaa cttggttaaa cctttgttgc ctggttcaac gatcgggatc gtcggtggcg
    21901 gtcaattagg tcgtatgatg gcgattagtg caaaagaaat gggctttaaa gtaggtgtgc
    21961 tggatcctgt gagcgattgt ccagccgcac aagttgcaga ttggcacatt gaaagtgtct
    22021 atgatgacac ctttgcgctg aaagagcttg ccagaagaac agatgtcatt acctatgaat
    22081 tcgaaaacgt cagtatagag gcgttaaatg cgattttacc catgtcattt attcctcaag
    22141 ggacagactt gcttgcgatt acgcaagacc gcctgttaga aaaatctttt ttggaaacga
    22201 ataacatcgt gattgctcct tatgcaacga tcgtcagtcc gacggatatc caagatgcga
    22261 ttgacgggat cggctatcct tgtgttttga aaaccactcg aggcggctat gatggcaagg
    22321 ggcagtatgt tttgaaaagt cgggcggatc tagctcctgc catggacctt ttaagagaag
    22381 gaacctgtgt tttagaagca tggatcccgt ttgaaaaaga gatttcgatc atggtggcag
    22441 gaaatggtca aggagatttc acgacttttc cggtcgtgga aaacatccac cacaacaata
    22501 ttcttcatga aacgattgct ccagccgcga ttgatcagga tgtgatcgag gaggctgagc
    22561 gtattgcccg tgtgattgca gaagcagtga gcctttcagg tgttttaggg gtagaaatgt
    22621 ttttaacaaa aacaggcggg ctatatgtga atgaattagc tcctcgtcct cacaattctg
    22681 gacattattc tattgaagct tgttctatga gtcagttcga tgcccatatt cgaggtattt
    22741 gtggttggcc attaggagaa aaagtacgtt tgataagcaa tgcagtaatg gtcaatgttt
    22801 tgggagaaca actgctggaa agctatcgct tgattgagaa taagccagac tggcaattcc
    22861 atttctatgg aaaaaaacaa gcaaaaaaag gtcgcaagat gggacatatc actatcttga
    22921 cagaagacat ccagcaaacg ctggaagaaa tcaaacaaac gaatatttgg gattagagga
    22981 gaaaaaacat gttagaacgt tatacacgcc ctgaaatggg gaatatctgg acggaagaga
    23041 acaaataccg tgcgtggctc gaagtcgaga ttttagcaga tgaagcttgg gcagaacttg
    23101 gtgaaatccc gcaagaagat gtgaaaaaaa ttcgtgagca tgcatcattt gatatcgatc
    23161 ggatcttgga aatcgaaaaa ttaacacgcc atgatgtcgt tgcgtttaca cgagcggttt
    23221 ctgaaacatt gggagaagaa agaaaatggg tccattatgg tctaacaagt acggatgtcg
    23281 tagatactgc ttatggctat ctcatcaagc aagcaaatga tattttacgg gaagacttga
    23341 aacgttttac ggaaatcatt ggcgaaaaag caaaagaaca caaatataca gtgatgatgg
    23401 gtcggacaca cggtgtccat gctgaaccaa ctacttttgg attgaaactt gccacatggt
    23461 attcagaaat gaaacggaac atcgaacgat ttgaacatgc ggcaaaagga gtagaagcag
    23521 gaaaaatctc aggagcagtg ggaacgttcg caaatatccc gccatttatt gaagagtatg
    23581 tatgtaaaca attggggatc cgtccacaag aaatttctac tcaagttctc cctcgggatc
    23641 tacatgctga atatttctca gcgatggcgc ttattgctac aagtattgaa cgttttgcaa
    23701 cagagatacg cggattgcaa aaatccgaaa cacgtgaagt agaagaattt tttgcgaaag
    23761 gtcaaaaagg ttcttctgct atgccgcaca aaaggaatcc gatcggttca gaaaatatgg
    23821 ctggtctagc cagagtggtg cgcggacaca tggtcactgc ctatgaaaat gtcacattat
    23881 ggcatgaaag agatatttct cattcttcag cagaacgaat catcttgcct gataccacga
    23941 ttttattgaa ttacatgtta aatcgttttg gcaatatcgt taaaaatcta acggtctttc
    24001 ctgaaaacat gaagcggaat atgtctgcaa catttggttt gatttatagc cagcgcgtta
    24061 tgctgaaatt gatcgataag ggaatgacaa gagaagaagc ttatgatctt gttcagccaa
    24121 aaactgcgta cgcttgggac aaccaagtgc agttccgccc gctgttagaa gaagatccaa
    24181 ccatcacatc ggtattatct aaagaagaaa tagacgatgc ctttgattat catcatcatt
    24241 tgaaaaacgt tgacgtgata ttcaaacgag taggtttgga ataaagaaga gtgagttgca
    24301 aaattcaatt aaaatagaat agcaaaaata accaaaaaag aagcagatcc gttagcggtt
    24361 ctgcttcttt tagtttatta tattttctta tcaataatag gaacctgatt ttaaaagcgg
    24421 ctacctcttt accgtgcctc tttacataca aaaaatagag gaattaagcg taaatggctt
    24481 ggctattata actaaaatgc tggttatgga gatgttgcag caagttttcg agaaaagcgt
    24541 attccatctc ttgtccattg aataagatct ggatacgata atgatttttg aaacgcttct
    24601 gttcatgaat ctgactgatt gaaagttcgc ctttgtgttc tgtctgataa agaaaagtcc
    24661 ttttacggca ttcagcacag cgcttggttg ctcggcggat ttttcggaat gtataaaaac
    24721 tagtatcttt attgcataaa taaacgtctt tgatcgacag caaatcatta tatagacagg
    24781 aacgttcttc agctgttaat tctgataaaa aaagctgacc ttgttttatt gcatcttcca
    24841 tcggcaagtg cctcctcgaa cccattatcc aaatttttag ttaattctaa tataccatca
    24901 ttaagtataa atgtaaacgc ttgttgatgg tataagattt tcgtttctga taaaacacga
    24961 acattaaaag aatctaatgc cttaaatgta catatttttg ttgatttata aaaagatgat
    25021 tgctaaaatt taaagtgaaa aaacgaacaa aaaacgatgt atttgctttt aatgtaaata
    25081 aaaaggagag acgtacatgg agaagaaaga acttttgtat gaaggaaaag ccaaaaaaat
    25141 atatcttact tctgatgaga acttgatttg gatagaatat ttagatcaag caactgcgtt
    25201 gaatggcgcg aggaaagacc agataagtgg aaaaggagaa ttgaataatc aaatcacaag
    25261 tgcaattttc cgttatctga ctcaaagagg aataaaaaat cattttattg aacaattgtc
    25321 taaaaccgaa caattagcaa aaaaagtaca aattatccct ctggaagtgg ttatccgaaa
    25381 tattgcagca ggaagtttct caaaacgtct aggtgttccc gaaggtaaag aattcatcaa
    25441 accaatcatt gaattctact ataaggatga ccagttggat gatccattta tcaatgaaga
    25501 gcatatctat ttcttacaac ttgcaaagcc ggaagaaatc agtgagctga aagcccaagc
    25561 gttggctatt aatgaaattt tgaccgaatt atttgctaag gtcggtttgg ttttagtaga
    25621 tttcaagcta gaatttggcc ggtcgaatgg acaaattttg cttgcggatg aagtaacacc
    25681 ggatacttgc cgattatggg atgaacgtac gaatgaacat atggacaaag acgtttaccg
    25741 cagagatcta ggtgatttga tcccagtcta tcaagaagta tataaccgtc tatcggaact
    25801 aactgaagaa aaggagcgag tatgatgtat ttcgtaaaag tatatgtaac ctataaagat
    25861 tcagtgttag atcctcaagg ggaggcagta aaaaaagcag tccatcgtat gggatatgaa
    25921 acaatcgaag atatccgaat aggaaaatac tttgagatac aacttgctga tgcagaagaa
    25981 ccaatcgata cagtgattga aacgatttgt gacaagctgc ttgcaaatgt aaatatggaa
    26041 acataccgat atgaaatcaa aaaaatggag gaagtataac atgaaatttg cggtcatcgt
    26101 ttttccaggt tcaaattgtg acgcagatat gttatgggca gttcgcgaga tcatgggcgc
    26161 tgatgccgaa tttgtacggc atgatgagtc ctctttagaa ggatttgatg gggttttact
    26221 gccgggagga ttctcctatg gtgactattt gagatgcggt gcgattgctc ggttttctac
    26281 aatcatggaa gaagtgattc gttttgctga agaagggaaa ccagtattcg gtacatgcaa
    26341 tggattccag atattgacag aagcaggact tttgccaggt gtactgagac gaaatgagtc
    26401 tttgcatttt atttgcaaaa ctgtaccatt gaaagtcaac cccaagacgg cctttacttc
    26461 agagtatgaa gccgacgaaa taatctatct tccagttgct catggggaag gaaattattt
    26521 ctgtgacgaa gaaacacttc aagaactaaa aaaaaataat cagattgcct ttacttataa
    26581 tgacaacatc aacggcagcg tggaaaacat tgcagggatt acgaacaaag cagggaatgt
    26641 gttaggaatg atgcctcatc cagaacgtgc agtagaagac ttgctaggat cagaagatgg
    26701 gaaacggttc tttgcttcca ttttaaaaaa cttcggaaag gtgaccgtat agatgaaaac
    26761 attgaaagaa ccgacagctg aagagatcaa gaaaaaaaga atctatgccg aatggggatt
    26821 gactgatgaa gaatatcgaa tgatcgaaga agatatctta ggaagaatgc ctaattatac
    26881 ggaaactgga ctgttttctg ttatgtggag cgaacattgt tcctataaaa attctaaacc
    26941 ggttctacgc aaatttccta ctagtggacc tcatgtgttg caaggccctg gagaaggcgc
    27001 aggcatcgtc gacatcggtg atggactagc agttgtcttc aaagcagaaa gtcacaatca
    27061 tccttcagcc gtggagcctt atgaaggagc tgcgacagga gttggcggaa tcatcagaga
    27121 tattttcagc atgggggctc gtccaattgc gttgctagat tcattgaggt tcggcgaatt
    27181 agataatcca agaacgaaat atttactaga agaagtagtt gcaggtatcg gcggatacgg
    27241 caattgtatc ggcataccga ctgtaggcgg cgaaattgca tttgatcctt gttatgaagg
    27301 aaacccatta gtcaatgcaa tgtgcgtagg tttgattgaa cacaaacata tccagaaagg
    27361 gcaagccgct ggcgtcggta attcgatcat gtatgtaggt gcaaaaacag gtcgcgacgg
    27421 tatccacgga gcaacttttg cctcagaaga atttaatcaa gaagaagaac agcaacgttc
    27481 tgctgtacaa gtaggcgatc cttttatgga aaagctgctg cttgaagcgt gtttggaatt
    27541 aatcttgcat cattcggatt ctctaatagg tatacaggat atgggagcag caggacttgt
    27601 ttcatctagt gcggaaatgg cttcaaaagc tggctcagga cttatattga cattagatga
    27661 agtcccacaa agagaaactg ggatgacacc ttatgaaatg atgttatcgg aatcacaaga
    27721 acggatgttg atttgtgtta aatcaggaga ggaagaaaaa atccaagaac tatttcagaa
    27781 gtatgatcta gatgcagtca ctatcggtaa agtaacagac gacgggcaat atcggctata
    27841 tcatcaagga gaagaagtag caaatctgcc agtcgatgca ttagctgaag atgcaccagt
    27901 ttatcataaa gaaatgaaag aaccagctcg aatcgtagaa tttcagcagt tagctcctta
    27961 tcagccagtt atcgaagaac ctggacaagt attgcttgat ctgctgcagc aaccgacgat
    28021 tgcttcaaaa cgttcaatct acgaaactta tgattcacaa gtacaaacca atacagttgt
    28081 ccgtccagga agcgatgctg ctgtgatgag ggttagaggg acgaataaag cgttagctat
    28141 gaccacagac tgcaacgcgc gctatctgta tttggatcca aaaatcggag gacaaatagc
    28201 agtggcagaa gctgctagaa atattattgc tagcggtggt aagcccttgg cgatcaccga
    28261 ctgcctgaac tatggttctc ctgataaacc agaagttttt tgggaattat cgacttcagc
    28321 tgacggaatt gctgctgcgt gtgaaacgtt aggaactcct gttatttcag gaaatgtctc
    28381 tttatataat gaaacggatg gtcaagcaat ctatccaaca ccaatgattg gtatggtcgg
    28441 attgattgag gatcataaac atatcactac tcaggaattc aaaaaatcag gggatctaat
    28501 ctatatatta ggtaagacgt ttgcagattt tgatggcagt gaattacaaa agatgcagct
    28561 tggaagaatc gaaggtgtga tccgaaactt tgatctatcc attgaaaaga gaaaccaaga
    28621 gttagtattg acagccatcc aaaacggatt gattgaaagt gctcatgact gttcagaagg
    28681 tggcttggca attgcactgg cagaatcagc tttcaaacat cagctaggga tatctgtaca
    28741 gtttgaattg tcctctgctc aattatttgc agaaactcaa tcaagatttg tgttgacagt
    28801 cgcaccggaa aataagacac gattcgaaga aatgatggga gatgctgctg ttttagcagg
    28861 taaggtgacg gatgaagcga taatcgaaat ttcagcaact gacggtcaga tcaaaataga
    28921 aactgcagta gcaagaaagt gctgggagga tgcaatcgta tgtcttatga agtgaagagt
    28981 ttaaatgaag aatgcgggat cttcggtgtt tggggtcatc cagacgccgc tagtgtggca
    29041 tacttcgggc tccatagtct tcagcatcga ggacaagaag gtgcaggtat cgtgtccaat
    29101 gatcgaggaa agcttaaggg gcatcgagat ttggggctgc tttctgaggt attcaaagat
    29161 caaagaaaat tgcagcagtt aacaggagaa gctgcaatcg gacatgtacg ttatgcaaca
    29221 gcaggcaatg gaagtgtgga caatattcag ccttttctat tcaaatttca tgatcagtcg
    29281 atcggcttag cgcataatgg taacttgatc aatgctcgtt cccttagaaa agagttagag
    29341 gaaaatgggg cgatcttcca ttctaactcc gatacggaga tattgatgca tttgatccga
    29401 cgaagtgaag aaacagattt tttaaataaa ttaaaaagtg ctttgaatga agtcaaaggt
    29461 ggctttgcct atttattaat gacagaaacg gcaatgattg ccgctttgga cccaaatggt
    29521 tttcgtccat tagcaatcgg acaaatgaaa aacggagcat acgtgattgc ctcggaaact
    29581 tgtgcattag aagttattgg ggcacgtttt ataagagatg tccagcctgg tgagatagtg
    29641 atcatcaatg acgaaggaat ccagattgat tgctttacga aggacacgca gctttctatt
    29701 tgttcgatgg aatatatcta ttttgccaga ccagattcaa acatcgcagg gatcaatgtg
    29761 catactgcac ggaaaaatat gggacggaat ttagcgaaag aatcgccagt aaaagcagat
    29821 atggtcgttg gcgtacctaa ttcttctttg tcagccgcaa gcggttatgc ggaagctagt
    29881 ggaatccctt atgaaatcgg attagtaaaa aatcaataca ttgcccgaac atttatccag
    29941 ccaacgcctg agctaagaga gcaaggtgtt cgaatgaaat tatctgctgt acgaggagta
    30001 gtggaaggta aaaaggtgat tatggtcgat gattcaattg ttcggggtac gacaagcaga
    30061 cggatcgtcc atcttttgaa agaagcaggg gcaaaagaag tccatgtgag gattgcttct
    30121 cctcctttga aatatccatg tttttacggg attgatattc aaacgcgtaa agaactcatt
    30181 gcggcaaatc acacgattga tgaaatcaaa gaatgtatcg gtgcagattc tttaggtttt
    30241 ttaagtgaag agggtctgat cgaatcgatc ggtctggaaa aagatgctcc gtattcagga
    30301 ttgtgtatgg cttatttcaa cggagattat ccgacgccgt tatatgacta tgaagaaaaa
    30361 tatcaggaat cactaaaaga aaaagtatcg ttcttttaaa agcagaccaa gaagggagta
    30421 tatgaattca atggcaaatg catacgcaaa agctggcgta gatgtcgaag ctggatatga
    30481 agtagtagaa cggatcaaga agcatgtcaa aaaaacggaa cgtttaggta tgatgggcgc
    30541 tataggagga ttcggcggtt gttttgattt atcggtcttt caattaaaag agccagtcct
    30601 tgtctcgggg accgatggcg tggggacgaa attagcagtg gcaatcgaag cagacaaaca
    30661 cgatacaatc gggatcgact gcgtagcgat gtgtgtcaat gatatcttag cacaaggcgc
    30721 agagccgtta tatttcttag actacttagc aacggggaaa aatgatccgt tacgtttgga
    30781 aaatgtagta aaaggtgtag cagatggatg tgttcaagga aatatggcgc tgattggcgg
    30841 agaaacagct gaaatgcctg gtatgtactc aggtaatgat tatgatctag ccggatttgc
    30901 tgtagggata gctgaaaaat ctcaattatt gacaggagaa acgatcaacc caggagatgt
    30961 gttgcttgga atagcatcta gcgggattca ttcaaatggg tactctcttg ttcgcaaaat
    31021 tttctttgag cagcagcagt tttctttatc atcaaaactg ccagaattga aaaaaacact
    31081 tggcgaagaa ttgcttgagc caacgaaaat ctatgtttct tccttgcttc cgctgatcaa
    31141 agaaaagaaa ataaaaggag ctgcacatat cactggtgga gggtttgtag aaaatatccc
    31201 gcgaatgtta ccagaatcta tggctgcaca aatcaaactt ggctcatggc cgattcttcc
    31261 aatattcggc tgtttacaaa aatatggtga aattcctgag atggagatgt atgaaatctt
    31321 caatatgggc atcggtatgg tcctggcagt cgaagaatcg aaagtaaaag aaatagtaca
    31381 cgaaattgag caagctggcg aaaaagttta tgaaatcggg aaagtgatcg ccaaagaaaa
    31441 acatcgtgtg gtgtttatag gagaagaacg atgagaatcg ctgtttttgc ttctggaaac
    31501 ggaagcaact ttcaagcgct agccgattat ctatcgaaaa aaggattgga atcttcgatt
    31561 gactggttgt tttgtgatca gcctgaagca tatgttttga aacgtgcaac tgcgttgagt
    31621 gtaccggcag attgtttttc acctaaagaa tttgattcaa aaaaagagta tgaagaagca
    31681 attttgcata aattgaaaga aaaaaagatc gatttgatcg tattagctgg atatatgcga
    31741 atcattggac cggtattgct gaaaaattat gataaaagaa tcatcaatat ccatccgtct
    31801 cttttacctg ccttccctgg tttgcatggc atacgtgatg cctttgaagc tggagtaaaa
    31861 gaaacgggtg tcacaattca ttatatcgac caaggtgtag atactggacc aatcatccgg
    31921 caggaaaaag tgagaattga acaggaggac acgttcgatt ctttagaaga aaaaatccat
    31981 agagtagagc atcgaatcta tccagaagtg attagtgaaa ttattgaaaa tggaggctat
    32041 ctgaaatgac aagagcattg atcagtgtat cagataaaac tgggattgta gcattcgccc
    32101 aaggtttgat tgaacaagga gtagaaatca tttcaacagg aggaacaaag catgcgttgg
    32161 ataaagctgg gatcaaaacg ctttcgatcg aagaagtgac agggtttcct gaaatgatgg
    32221 atggccgtgt caaaacactt catcctaaaa tccatggtgg tcttttagga agacgcgatc
    32281 tccctagcca tatggaggca atggaaacgg aaaatatcca accaatcgac tttgtttgtg
    32341 tcaatttata tcctttcaaa gaaacgatta tgaaaccaga tgtcgaaata gcagaagcta
    32401 ttgaaaacat tgatatcggt ggtcctagta tgctccgtag tgcagcaaaa aaccatgaat
    32461 ttgtcacctc tgttgttgat ccatctgact atgaagaagt actttcagaa ttacgtcagt
    32521 atgggcatac ttcactttct ttcagacaaa aactagcggc aaaagtcttt cgtcatactg
    32581 cggcatatga tgcactgatc gctcaatact taacggattg ggtggaagaa aaagaaccgg
    32641 aaaaattgac acttacgtat gaacgaaaac aaacgcttcg ttacggtgaa aatagccatc
    32701 aagccgctgc cttttatcag tccgctcttc tggaaaaata ttcgatcgca gcagcaaaac
    32761 aactccatgg gaaagaactt tcttataata atatccgaga tgcagatgct gcgctacgga
    32821 tcatgaagga atatgacgag ccaacggtag tcgccttgaa acacatgaat ccttgtggta
    32881 ttgggacagc atctacgatt ttagaagcgt gggaagcagc gtatgaagca gatcctgttt
    32941 caatctttgg tgggatcatc gttttgaatc gagaagtaga tctgccaaca gcagaacaga
    33001 tgcataagct gtttctagaa atcatcattg ccccttctta tacacaagaa gctttggaat
    33061 tactgcaaaa aaagaaaaac atccgattac tgacagtaga ctttgcgcag gaagaaaatc
    33121 aaaatcgaga agaaacggtc tcagtcttag gtggacttct tgtacaagat caagatctgg
    33181 caatagaaaa tgaagaagag tggaaagtcg tgacaaaacg taagccgact ccagcagaag
    33241 caaaagcatt agtgtttgct tggagagctg tcaaacatgt gaaatctaat gcgatcgtac
    33301 tggcaaacga acgtcagaca gtaggaatcg gagccgggca gatgaatcga gtcggttcag
    33361 taaaaattgc gattgaacaa gcgcaagaga aaatggaagg tgcagtttta gctagcgatg
    33421 cttattttcc aatggatgat tcggttgaat atgcagccaa acatggtata aaagcaatca
    33481 ttcagccagg aggaagcatc aaagaccaag attctattga tatggcgaat aaatacgatc
    33541 tagcaatggt ctttactgat gttcggcatt ttagacatta gagaggagtc ggataaatga
    33601 acattttggt gatcggtgca ggtggtcgtg aacatgcaat aagtaaaaaa cttttagcca
    33661 gtccgaaggt ggatacggtg tattgtgcgc caggaaatcc ggggatgaca aaagatggta
    33721 tcaattgtgt cgctatcagt gagcgagatc attcagcgtt aatccatttt gttaagaaag
    33781 aggctattga ttggagtatc gttggtcctg aagttccttt gttaaatggg atcgtcgatg
    33841 attttatggc ggaaggattg aaaatcttcg gtccgacaaa agcagcagct ctgatcgaag
    33901 gttcgaaaag ttttgctaaa caattaatgg atacttatca aatcccgaca gctaaatcca
    33961 gaagttttga atgttacgaa aaagcagcag cgtatatcaa agaaaatggt gcgccaatcg
    34021 tagtgaaagc ggacggctta gcagctggga aaggtgtagt cgtggctacc acagtgaagg
    34081 aagcgctgga tgcggcagaa caaatgttga accagcatcg atttggggat agtagcaaaa
    34141 aaatcgtcgt agaagagttt ttggcaggag aagaattctc ccttttggcg tttgtccgta
    34201 ataccaaggt gtatccgatg gtcatttcgc aagatcataa gcgggcattt gataacgata
    34261 aagggccaaa tacaggcgga atgggtgctt attcaccagt accgcaaatt tcaaaaaaga
    34321 tgattgaaaa agctgtggaa gaagttttaa aaccagcggc tttgggaatg aaagaactag
    34381 gacgctcttt cacgggtgtt ttatatgcgg gtttgattgc tacgaaggaa ggaccaaaag
    34441 tgatcgaatt caatgcgcgt ttcggtgatc ctgaaacgca agtcgttctt tctcggttga
    34501 agagtgactt tgcgcaagta atcgatgatt tattagagaa tcgtacagta gagttaaagt
    34561 ggcagcaaga aggatacaat gtaggcgttg tggttgcagc tgccggttac cccgaagaat
    34621 atgagacagg aatggttcta ccagattttc tggaagaaga gctttctgtt tactatgctg
    34681 gagtttcctc aaataacggc aaactagttg gagcaggagg acgtctttat ttagtagaag
    34741 catacggtga gacgatcaaa gaagcacaga aaaaaattta caccgcgtta atggataaaa
    34801 cgacagatgg aacattttat cgtacagata ttggagaaaa agctgccaat agcgaactga
    34861 tcgtgaagta aatcagctgc ttccatttat aaaaaataca acaaacataa tcggaagcgc
    34921 cgattttagt gaagcctttt cataaagagt gtggtacact tttgttgtgt atataaataa
    34981 ggaggagttc agatgaaaaa aattcaatta ggtacttctg atcagaaagc agctgcagtg
    35041 atcttaggct gtatgcgtat caacaatgcg gaagatccag taaaagtgat tgagacagct
    35101 tatgaaaacg gcattgattt ttttgaccat gcagatattt atggaaacgg tgaatgtgaa
    35161 gaaatctttg cagatgctct agcaaaaaca tcaatcaaac gagaagatct ttttattcaa
    35221 acaaaatgtg gaatcgttcc aggtgtgatg tttgattttt ctaaaaaaca tatcattgaa
    35281 tctgtagaaa aaagtttgac ccgtctgaaa atggattatg tggatgcttt acttcttcat
    35341 cgtccagata cattggtaga accagaggaa gtagctgaag cgtttgatga attggaacgg
    35401 tcaggaaaag ttcgttattt tggcgtcagc aatcaaaaac caatgcaaat cgaattgctg
    35461 aaaaaatatg ttcgtcaacc attagtagct aatcagctgc aatttggctt gaaacatact
    35521 ggaatgatcg atcaagggat tcatgtcaat atgacagatg aagcaagtat cgatcatgac
    35581 ggtagtgtac ttgattattc ccgattgcat gatatgacga tccaagcatg gtcaccatac
    35641 cagtatggat tttttgaagg tgtatttatc gggaacgaaa aattccctga attaaaccaa
    35701 acattagaag aactagcagc taaatatcaa acgacaccaa ctggcttggc ttctgcttgg
    35761 attttacgcc atccagccaa tatgcaagtg atcgccggta cgatgaacgt agggcgaatc
    35821 aaggaaatcg ctcaagcttc agaaattaat atgtctcggg aagattggta cgaattgtac
    35881 cgtgctgctg gaaacatttt accttaaaga ttgtcataag caggtcaaaa gggctataaa
    35941 ttaaaaagac agaataactt gaaagctgtt ttcagcttcg agatattctg tcttttttta
    36001 ttgcaaatgg aaagagtatc attgtacgga tttcgtttat tagttatttt tgtttttaag
    36061 gaaaagctgt gtccgatatt cttttggaga aatcccttgt tttttcttaa ataaataact
    36121 gaaatagtta gggtcattat aaccaatttc aaaagcaata tctgaaatac gatagtctga
    36181 ttgctgcaat aatttttttg ctaattcgat tctttgttct gtcagataat cgatgaatgt
    36241 ttggttaaac gattgagaaa aaatcgtact gaaataagag ggacttaatg caacttgttg
    36301 agcgacccaa gttaaggaca tatctggatc ggtaaaattt tctttgataa aatccaatgc
    36361 atggttcaaa attggctgat atttgttcct tgaaggctgt gagggcagag cagttaagaa
    36421 agaaatgaac atataaactg tcgaacggta aagcgagtcg tcggcgctga ttgctaagcg
    36481 ttgactggtg gatgtgcaat gaaccatttc ttgcgggatt ttcttttctt tcaggcagac
    36541 atgctggagt agcttagtca agacaaataa acgatataat cgtgttcgag ttggtgtgcc
    36601 ttgtggtttc gtcaagtgtt cgatgtactt agatacttcg tttttcgata atgaagacaa
    36661 atcaagtgag aggtcaaagt aaaagacaga atcaactgga agtttcgctt cttgaatcaa
    36721 atcctcatag ctgataattt gttctttaag ggaactggcg gtttcaagta tcatctgcgt
    36781 gatctcaaaa gatgcaggta attcgctgat tctttctgcg acaggaccaa tggcgacaga
    36841 aaaattattt ttttgtccct tttctaattc atggaccaac gtttgggcta cctgataact
    36901 ggtctcgatc acattttctt caagagaatc aactattaaa aatttgatga atcgagagga
    36961 aacagcagag aagatcactt gttgattctc cctaaataaa aacttcaaat aatcactgag
    37021 atgagcgtaa tcttcaaagt ctgtactgac ttggtttgct gctaataata cggtcatttt
    37081 tttccctgct aaagagcgat tgaaagattc agcaagtttc aatgtttcac tgatcgtaag
    37141 tgagcctttg aacaaaccgt tcaagaaatg attttttttc aattcgaaaa caagatcaga
    37201 agaagtgtgc gtttcttttt gctgcaaatc taaagcagtt actgcttttt ctattgcttg
    37261 tttcaattcg ctacttttaa tcggtttaag cagataatca tctgcctgta cctggattgc
    37321 tcctttcata taatcgaaat cgtcgaatcc actaataaat atgagacgag tccaaggaag
    37381 tagtttcctt gcttcttttg aaaaagtcaa cccgtccatg aaaggcattt ggatatcagt
    37441 cagaatgatg tcgggctgta agtcgataat tgaagacagt gccatctcac catctccagc
    37501 ttcgccgaca taagtgattg gataataaga accaaggaca gttatttgtt cccgcaagtt
    37561 attgcgaatg aggtattcgt cttcgatgat aaaaacttta tacatgtttg tttcctccaa
    37621 ttgttttggg agatagaggg atcatcagtg tgacagttgt tccttctcgg tatttgctgt
    37681 caatcgtgat aggtttttga tcatttccgt aataaagaag gagacgcttg tttacgttgt
    37741 aaagtccgta gccgatactg aaatctgaat cgatcccttt ggctaactct ttacgtattt
    37801 ctgccagttt ttctgcaggg atgccaatcc cgttgtctat aactttgaat tggatcatct
    37861 catcaatttt gcatgtggta atacgaataa atcctttgtg acggacgtac ttcgttccat
    37921 ggtatacagc attttcaatc aatggctgca agatcatttt taaaatagaa acaggaaaaa
    37981 gtgtttctgg tatatcgatc ttatagtcaa gcatatggcc gtatcttatt tttaagatga
    38041 ctagataatc attgatatgg ctaatttctt tttcaagagg aatccagtct tgtcctttgc
    38101 ttaaagacgt acgaaaaaag ccggaaagtg catgggtcat agtcagagct tcttcaaagc
    38161 agtcttgttc gatcaaagaa ataatggcat ccaaactgtt ataaataaaa tggggagtaa
    38221 tctgagcttg caatacacga acttcacttt gtgctaaatg gtattgtttc aaagcgttct
    38281 cccgtaaaga ctggtttaga tcttccgcca ttttattcat gctagcggta agtgtttgta
    38341 attccagtgt ttccggcagg gttaaacgaa agccaaggtt ccctgaagaa agttgttctg
    38401 acatctcgat cagctgattg atcggttctt ggacctttct ctctaaaaag cgacgattct
    38461 ttttcgcata gaaaaaaatg gtactaagaa ctccaagttc cactattgtt aatagaatga
    38521 gcgagcggac aagtgtcgta ttttttttgc ttgctaagtc gatctccaca cgaacaaaat
    38581 cttgtaagat atctgacagc agttgagtga cagaatctac ctgattgatg atctcttcat
    38641 tggtatccat aaaatctttt gccaagatat tattgatcag ctcgttttga taatcttcca
    38701 gtgtatcgat cgtacgtagc gatacatcta acgtactaat ttctttaagt gtatttgtat
    38761 tatttttgat ctctcgaata tcattcctaa gttcttctag gatattttcc tcattgaact
    38821 catctacggt tacttggcca gaaatcaagt cccacatact ttccaaaact ttttgatcaa
    38881 ccttcaaagc aattgcatct gctttttgga tatttgcgat cgtctgttga taaatcaaaa
    38941 gctgttgcga atataacagt atgctcagta gcaaagggat aacagcaaat agaagcatgg
    39001 ctttgtttgc ttgggcaaaa atctgtttta tgcttaaatt ttttgtcatg atacttctcc
    39061 agtcaataat ttctggttgg gatgttagct atattctgct gggaaaagac agtctcggaa
    39121 ataaaaatat ctttaggtaa tgtttttcct gtttgaatat ttccaaaata acgagtaacg
    39181 gtattggcta cataccagcc gacatcaggt ttacactcga ctacacaatt gacgattcct
    39241 gagcgtagct tctcgatcat atcttcttgt ccatcaatag ttacaatgat caaatcttct
    39301 ccaggtttga ttgatgtttc ttttatcgca gctaaagcac cgtgagtcat ttcatcacta
    39361 tggctgtata atacatcgat ttcggataaa tcatttgttt ctaaatatcg tttcatctgg
    39421 tcttttcctt tcatccgaat aaaatcaccg acaattcggt gaacaatagt catcggaggt
    39481 ttatggtcga tggttccatc tttttttagg gttggtttac gattgattga ttccaaaaat
    39541 ccttcggagc gtagcttggt cggtgtggag ttctctgaac cagcaagttc taggattctg
    39601 atttcctgtt tctttgaatt tgtgaagtga ttgctgacaa ataaacccgc ccgatttcct
    39661 tctgctttga aactggggcc aatgtgggtg acgaaaagct cgggatcatt cgtttgaata
    39721 tgtctgtcga caagtatgac agggatccct gctcgctttg cttcttttaa tacagagtcc
    39781 cacccggatt cttgcaaagg agtaaaaatg atcatatcca ctttataggc aatgaacgtc
    39841 cgtatatctt ggatttgccg ttcctgattc atgtagccat ttcggtagag aacttggtaa
    39901 tcttcttttt caagcgcagt gataattgat tcagtatgct ttttccgcca gctactctcc
    39961 gttcctgatt gcgaaaaacc aacgactagt gggtcaggtg cttcctttgt attaggtgta
    40021 caccccatca tttggtaagc gattacaaca agggctaaaa aaaataaaac acgtttcact
    40081 ttaaatcact ccatctggat ttgttagtac tatcttatca gataaaaggg aaaatcaaag
    40141 tcaaaaggaa tcaatcgaaa aaaatccaag aaacttaaaa aaatccaaga caaaaaaagt
    40201 acacctaaaa aatttaaagt aaatcccata aaaaaatcaa tgttaacgct ttctttatta
    40261 gctatactcg gtgtatcaat tgaaatgggg gataaaaaat gaaaaacaaa tttagaaaga
    40321 ttgttgggac tatcgctatt ttgaccgcaa gcattctatt aagtgcgtgt ggcaattcag
    40381 gatctgcaga tgatagtacg gggtatgtag gaatcgctat gccgaccaaa tcagcagaaa
    40441 gatggatcgc tgatgggaac aacatggtct cggaattaga aaaactgggt tataaaacag
    40501 atcttcaata tggagaagat aaagtagaaa atcaagtagc acaaatagaa aatatgatta
    40561 caaaaggggt agatacactt gtgattgctt ctatcgatgg ttcggcttta actgatgtgt
    40621 tagctaaagc aaaagaagca gatatcaagg tgatcgccta tgatcgttta ctgatgaatt
    40681 cagaaaatgt cgattattac gcgacttttg ataattttgg agtaggtgta tcgcaagcag
    40741 cttatattga agagcactta ggattgaaag aaggaaaagg accattcacg attgaattat
    40801 ttggtggctc gcctgacgac aacaacgcac taatcaatta caacggagtg atgtctgttt
    40861 tacaaccata tatggacaac ggtcagttgg tcgtgccatc tggacagacg agtttcagtc
    40921 aaatcgctac gcttcgctgg gatggttcta cggcgcaagc aaggatggat aatctgttaa
    40981 gcgcaaatta tactgaccaa acattggatg ctgttttgtc gccatatgat ccaataagtt
    41041 taggaatcat ttcgtcatta aaaggcgtgg ggtatgggag tgaaagtaaa cctttacctg
    41101 tgattactgg acaagatgcg acagttgctg gcgttaaatc gatcattgcc ggggaacaaa
    41161 cacaaacgat ctttaaagac acacgtatct tagcaaaaaa tacgattgaa atgatcaaag
    41221 caatcagtga tggagaagag gttccggtca atgatactga aacttatgat aatggggtga
    41281 aaactgtccc tacgtattta gcaaatacag tatctgtcga taaagataat tatcaagcag
    41341 agctgatcga caccgattat tataaagaat ccgatctgaa aaattaagag gaaccaaaca
    41401 aggaactaaa gagatctaag tcagagagag gataagaatt atggcggatt gtattttaaa
    41461 aatggcagat atcaccaaaa aattttctgg aatccgagcg ttagattgcg tgaatctgat
    41521 gattgaacgt ggggaaatcc atgcattgtg cggagaaaac ggagcgggaa aatcaacatt
    41581 gatgaatgtc ttgagcggct tgtatccata tggctcctat gacggggaaa tcttttatga
    41641 tggaaagctg tgtcaattta aagatttgaa agatagtgaa gaaaaaggca tcgtcatcat
    41701 tcatcaagaa ttagcactaa gtccttatct ttcaataaaa gagaatattt ttctcggaaa
    41761 tgaacaagca gaaagaggcg tgattgattg ggaactgaca gaaaagaaaa catatgaact
    41821 gctgaataaa gtcggtttgt ctatcgaccc gaatcttcta gtatcccaga ttggcgtagg
    41881 gcaacagcaa ctagttgaaa tagctaaagc attatcaaaa tccgtccgtc tgttgatttt
    41941 ggatgagcct accgctgcat tgaatgaaga agaaagcgcg aatttgctga gattgatccg
    42001 agagttgaaa gagcaaggtg taacctccat cattatttca cataagctga atgaaatcgt
    42061 ggatatcgca gatcgaatca ccattttacg ggatggacag acgattgaga cactagaaaa
    42121 tgaaatgatc agcgaagagc atattattcg cggaatggtg ggcagagatt tagttgatcg
    42181 ttatcctgaa agaaaaccgg atattggaga agtttatttt aaagtagaag actggacggt
    42241 ctatcaccct cttgatcacg agcgaatcat aaacgaccac atcaacttgc atttgaaaaa
    42301 aggagagatt gtaggaatag ctggactgat gggagcgggc agaactgaat tcgctatgag
    42361 tctatttgga cattcttatg gaagcaagat atccggacgt atattaaagg aaggggcaga
    42421 gatatcagtt aagaccgttc cttcagccat tgcaaacgga ctcgcttatg tctcggagga
    42481 ccgaaaatct ttaggactga atctgctgat ggatattcgg gaaaacgtga cgctgagcag
    42541 tttggataaa ataagtcaaa aaggagtatt agataaagaa aaagaagtaa ctgaggcaga
    42601 aaatttccgg aaaaagatgc gtataaaaac aaactccatc catcaaattg tcagtagtct
    42661 tagtggtggg aatcaacaaa aagtcgtttt atccaagtgg ctgatgacac aacccgatat
    42721 tctttttttg gatgagccaa cccgtgggat agatgttggg gcaaaatatg agatctacac
    42781 gattatcgaa gaaatggcag caaatggcaa agctgtctgt cttatctctt ctgaacttcc
    42841 tgaaatatta gggatgtgtg atcgaatcta tacgatgaac gaaggacgta ttacaggaga
    42901 agtctcgcga gaagatgcag atcaggaagt cttgatgaaa ttaatgacga aagaagaggt
    42961 gggttaagtt ggaacaggca aaaaatctta cggataaaaa agagaaaaaa ctaaatttga
    43021 aaagtagagc agctgatctt tttggtcgct acagcatggt gatcatttta gcgggactac
    43081 ttattgcgtt tcaattgatg acggatggta ttttctggcg tccattgaat ataactaacc
    43141 ttgttctgca aaatagccat atattagtac tagctgcagg gatgttatta gttgtgctct
    43201 taggtcatgt ggatttgtcg gtagggtcag tgatggcgtt tgttggtgca attgcgggca
    43261 tgatgatggt caatcgccaa atgaacccgt ggatgacagt tatcgcatgt cttgcagtag
    43321 gcgggctgat cggcgcatgg caaggttttt gggtagctta tgcagggata ccggcgttta
    43381 tcgtgacttt agcaggattg ctgatgtttc gtggactgac acaagttgtt ctaggaggcc
    43441 aatctctagc accttttcca gctgttttcc aaaaaatgtc tacgggttat ttaccagact
    43501 taagcgaagg aagcagcctt cacttcttga cattgatttt aggaatgatc atcacgatcg
    43561 tgttagttgt tggtcaatgg cgaacaagaa atcgtcggaa aaatcattta tttgaagtgg
    43621 aatctccaac agctttcttg gtaaaggcgg tatttacagc agtcgttgta ctaggaataa
    43681 cttatatctt tgcctcttat caagggtatc cgattatttt gatcattctt ggtttgatcg
    43741 ttgcagcata tgggtttttg acaaataaaa cagtagcagg tcgacagatt tatgcgacgg
    43801 gcggaaatcg aaaagcggct gaactatcag ggatcaaaac aaagcgaatc acgttctggg
    43861 tattcgtcaa catgggagtc atggcagctt tagctggatt agttttagct gctcgattga
    43921 atgcggcaac acctcaagca ggtacatcga tggaactgga tgcaatggcg gcagtatatt
    43981 ttggtggtgc ttcgacttcc ggcggcattg gaacaatcat gggtgcgatt gtcggtggct
    44041 tggtcatggg tgtattgaac aatggcatgt cgattttagg cgtcggggta gactggcagc
    44101 aggcaatcaa aggattgatc ttgcttttag ccgttgtgct agacttgtat aataagaaaa
    44161 aacgaacaac gtaggagaac gccggttatt cagaaaaaag actgtgacaa gacatttgtc
    44221 acagtctttt tttcgctaaa agcgaacatt cattgtttcg tttgtataga ctaaaaataa
    44281 tatatgtttt tttaccattc gtataaattc tctttttgct cttgattttt ttgcttaatt
    44341 gagttaaatt acatagggcg ctaaaaaaag ccttgattaa attaataatg ttcgtgtttt
    44401 gctggatgtg aacatcagga ggataatgta atgaaagtat ttgattacga agatattcaa
    44461 ttaattccta ataaatgtat cgtaaatagc cgttctgaat gtgatacaac ggtcacatta
    44521 ggtaaacata cattcaaaat gccagtagtg cctgccaaca tgcagacgat tattgatgaa
    44581 acaatcgcag aattcttagc ggaaaatggt tatttctata tcatgcatcg gtttgatgaa
    44641 gcagctcgaa ttccgtttat caaaaaaatg aaaaagcgtg gattgattac ctcgatcagt
    44701 gttggcgtca agaaagagga atattccttt atagagaagt tggcagaaga atcgctaaat
    44761 cctgattata tcactatcga catcgcgcat ggacatgcta actcagttat tgatatgatt
    44821 cagcatatta aaaaatattt gcctgaaact tttgtgattg ccggtaatgt tggtacaccg
    44881 gaagccgtcc gtgaattgga aaatgcgggc gcagatgcaa caaaagtcgg gattggtcca
    44941 ggaaaagtat gtattacaaa aatcaagaca ggctttggga ctggaggctg gcaactggca
    45001 gctcttagat ggtgtgcgaa agcagctcgc aagccgatca tcgctgacgg tgggatcaga
    45061 acacatggcg atattgcaaa atctgtccgt tttggtgcga caatggtcat gattggttca
    45121 ttgtttgccg gtcacgagga atctcctggc gaaacaaaag tcgaaaatgg aatcgtgtat
    45181 aaagaatact ttggttctgc ttcagaattc caaaaaggcg aaaaacgaaa tgttgaagga
    45241 aagaaaatct ggatccaaca caaaggatct ttgaaagata cactagtgga aatgcaacaa
    45301 gaccttcaat catctatttc ttatgctgga ggaagagatc tggaagccat tcgaaaagtt
    45361 gactatgtca tcgtgaaaaa ttcgattttt aatggagaca caatctaaaa aataaataaa
    45421 atattaggat gttgtgaaaa agttgtcctg cattaagtaa taagaacagc caaacaaaaa
    45481 tagttcttta tatgttttgt ttggctggaa ttattatcgc agatacaagc ttttgaacat
    45541 cattattcag aataagggac tgtgataaga tttttgtcac agtcccttat gttttgcaaa
    45601 aaaagttttt cttttttctc gtaaattcgg taaaatcaaa agaaaaaata gacaatagaa
    45661 aagagaagct tatgtgggaa aaagtagaga aaaaacaagg accgatttat cgtcaaatta
    45721 tggaacagat tatgagagaa atcgaaaacg gaaggatcaa tcctggaagt caacttgaat
    45781 cagaacgaaa actagggcaa ctttttggtg tgaatcgttc caccgttgtc catgcattgg
    45841 aagagcttag ggagcttggg gtactaacga gcaaacgtgg cagcggatgg tttgttaatc
    45901 agactgaatg ggggaaattc gctgttccaa gaatcgattg gcggcaaatg atctctcctc
    45961 gttatgagca gacggactgg tatgagcaaa aaataagaga agcaaagcag atccaaaaaa
    46021 catcgtttct tgatttatac gctagcgaga tgccagatga gcttttgccg aattttgagt
    46081 ttccttctta ttctcttgaa gaaatcttag cggaagaaaa agaaatggat cttttaggct
    46141 atactccgtt acgtaacaaa atcaaacggt atttggaaag taaatttgaa ttggcatttt
    46201 cccccaacca gcttcttgtg actggtggcg gtcagcaagc aatctttttg attttacaaa
    46261 cgattctttc agctggagag gggatagctg tagagtcacc ttcttttttt taccgattac
    46321 ctcttttcaa agcttcagga acgcgtttat ttgggatacc gatggatgaa gaagggatcg
    46381 acttagaaaa actgaaagaa tcgatccata aaaataaatt gaaagcagtg cttatcaacc
    46441 cgaattttca aaaccctaca ggaaaagtga tgagtcaaaa acgacgagaa aagctagtag
    46501 aattgtgtcg acagtatcgg cttccaatta ttgaagacga tgtatttacg gatctttcat
    46561 ttctaaacca agaagaagtc cttcctatac gaacgattga tccggataat gtgttatacg
    46621 tcggttcgtt atctagggtt ttaggaaaaa caacgaaaat cggttgggtg ataggacctg
    46681 agacttttat ctcgcaacta gctcaagcgc aagaaatgat ggagttttcg atgaatatcc
    46741 ttacacaaat cacagtggct aatgtattta atgaagcaat tgatttgaaa atgcaagatg
    46801 taagaaaaaa gttgaaagaa aaaagccgac tgataagcgc ttggggagat tcacaatcgt
    46861 ttttcaagct tcattcaatt ttaggtggtt actatgcctg gattacttgg gatgggaaaa
    46921 aactagaccc cgaactagca gaaaaagtag tagatatggg tcttggaatt gcaccaagtc
    46981 tactttttgg gcaagatata aatggaatca gaatcaatta cagtaggctg gatgaaaacc
    47041 aaataccgtt gttttattca aagatgaaaa ttctagaaaa gtggttaaca gaataatttc
    47101 acaaagtaaa tagattaaag aatataacag cttggattta aatttcaagc tgtttctttt
    47161 ttttcggaaa aagaatacga tataaagaaa ctaagaaaaa accattattt gtacgtccgt
    47221 tcacgatgtg taaataaaat aaatgtttgc aacaaaactg tataacacca acgtttttaa
    47281 atagaaacag atggttgtaa gtttgattag aaaatagaaa aaatgcagat gaaatataaa
    47341 acgctttcct tattgtgatt ttattcacta atgctgttaa tatgcggatt ggcataattt
    47401 cctttcatcg tgaaaatttg tgcttttagc ttgtatttct cataaatcca tgataattta
    47461 ttaatgaaga cggttaaata gtgatacagt tttattcact gtttcaatcg cagaatgaag
    47521 agattttctt atagatgaga gaggaatgtg tgacaaatgg caaacaaaaa agcaccgatc
    47581 gacttccaag cactgctaga tgaagtcaat gcagatttcc cagtatatca agcacttgat
    47641 caagatggaa acgtagttaa caaagattta gtacctgatt tatccgatga tgaactcgtt
    47701 gaattaatga ctcatatggt atggtctcgt gtattagacc aacgttcaac agcgctgaac
    47761 cgccaaggac gcctaggctt ttttgcacca actgctggac aagaggcaag tcagctggct
    47821 agtgcttacg catttgataa agaagatgtt cttcttccag gttatcggga tgtacctcaa
    47881 ctagtaaaac atggtttacc tttatctcaa gcttttttat ggtctcgagg acatgctgca
    47941 ggtaattctt atccggaaga attgaaagct ctaccaccac aaattatcat cggtgcacaa
    48001 tatgtacaag cagccggtgt tgcattaggt ttgaagaaac gaaacaagaa aaatgtcgtc
    48061 ttcacttata ctggtgatgg cggttcatca caaggtgatt tttacgaagc aatcaatttc
    48121 gctggcgctt accatgcaaa tgccgtattt tatatccaaa acaacgggta tgcgatctct
    48181 acacctcgtg aaaaacaaac tgcagcaaaa acacttgcac aaaaagctgt cgcagctggg
    48241 attcctggta ttcaagtcga tggaatggat ccgcttgcag tatatactgt atctaaaatg
    48301 gcacgggaat gggcgatcag tggaaatgga ccagtcctaa tcgaaacact gacttatcgt
    48361 tatggaccac atacactatc tggtgacgat ccaacccgct accgtacaaa agacacagat
    48421 gacgattggc agaaaaaaga tccattgatc cgcttccgta aatatttgac ggaaaaagga
    48481 ctttggtctg aagaaaaaga agaacaagtc atcgaagcaa ctaaagaaga aatcaaagca
    48541 gctattgctg aagccgacaa agtaccaaaa caaaaggttt cagatttctt gaaaaacatg
    48601 ttcgaagtat ctccacaatc aatcaaagaa caaattgcaa tttatgaagc gaaggagtcg
    48661 aaataatcat ggcacaaaaa acaatgatcc aagcaatcac agatgcctta gcacttgaac
    48721 tagaaaatga cgagaatgtc gttgtttttg gtgaagatgt tgggaaaaac ggaggagttt
    48781 tccgggcaac tgaaggattg caggaaaagt tcggagaaga ccgagtattc gatactcctt
    48841 tagctgaatc tggaatcgca ggattgagtt tcggtcttgc gttagaagga tttcgtccag
    48901 ttcctgaaat ccaattcttt ggttttattt tcgaagcaat ggacgaagta gtagctcaaa
    48961 tggctcgtac aagatatcga atgagcggca ctagaaatct acccatcaca attcgttcgc
    49021 catttggtgg cggtgttcat acaccagaat tgcattcgga taatttagaa ggtttgatcg
    49081 ctcagtctcc tggtattcga gtagtgattc cttccaaccc ttatgatgca aaaggactat
    49141 tgatttcttc tattagaagt aacgatccgg ttgttttcct agaacacatg aaactatatc
    49201 gctcattccg agaagaagtg ccggatgaag cttacgaagt tcctttggat aaagcagcag
    49261 ttactcgtga gggaacagat gtatctatta tcacatacgg agcaatggtg cgtgaagcaa
    49321 tcaaagcagc agacaatctt gcaaaagaaa atatatctgt tgaaatcatt gatcttcgta
    49381 cagttgcgcc attagatgta gaaacgatca ttcaatccgt ggaaaaaact ggtcgcgtag
    49441 ttgttgtcca agaagcacaa cgacaagcgg gcgttgccgc gcaagtagtt tctgagatct
    49501 cagaacgcgc tatcctttca ttagaagccc caatcggacg agtttctgca cctgatacag
    49561 tcttcccatt tggacaagca gaaaatgtct ggttgccaaa tgcaaaagat atcgaagaca
    49621 aagtaaaaga aatcgcggaa ttttaagaaa agaagggacg aaacaaagtc atggcttatc
    49681 aatttaaatt gccggatatc ggtgaaggaa tcgcagaagg tgaaatcgtc aaatggttcg
    49741 tcaaaccagg agatacgatc aatgaagatg atacattact agaagttcaa aatgacaaat
    49801 cagtagaaga aatcccgtca cctgttacag gaacggttaa aaatgtgatt gttccagaag
    49861 gtaccgtagc aaatgttggg gatgtattag tagaaatcga tgcaccagga cacgaagaca
    49921 atgaagggga cagtggtgta gccgcagaat cccaaactcc agctaaaccg gctgctgaac
    49981 ccactgttga tacagaatca gctggatcgt caagcgaagg agtcttccaa tttaagttac
    50041 cggatatcgg tgaaggaatc gcagaaggtg aaatcgtcaa atggttcgtc aaaccaggag
    50101 atacgatcaa tgaagatgat acattactag aagttcaaaa tgacaaatca gtagaagaaa
    50161 ttccgtcacc tgtcacaggg acagttaaaa acgtgattgt tccagaaggc actgtagcaa
    50221 atgttgggga tgtattagta gaaatcgatg ctcctggaca caatagtgca ccgtcaacta
    50281 gtgcgccatc agctgaagca ccaaaagaaa aagtggaaac atcaggttca gcaagtgtcg
    50341 ttgaagctgc cgatccaaat aaacgtgtat tggctatgcc atctgttcgt caatttgccc
    50401 gtgaaaaaga tgtagatatc tcacaagtaa ctgcaactgg aaaaggtggc agagtaacaa
    50461 aagaggacat cgaaaacttc ttggcaggtg gtccaagcag tgcaccagcg aaatcagaag
    50521 cgccagaagc ggcagcaccg aaagaagcag ctcctgcagc agaaagcaaa ccagctgcac
    50581 cagcaaaacc attcaagtcc aacttaggag acttggaaga acgtgtagca atgacgccaa
    50641 cacgtaaagc tatcgctaaa gcaatggtca acagtaagca tacagctcca cacgtgacat
    50701 tgcatgatga agtagaagtg tctaaactat gggataatcg gaaacgattt aaagaagttg
    50761 ctgctgcaaa tggtacgaaa cttactttct tgccatatgt cgtgaaagct ttaacagcga
    50821 ctgttaagaa atacccagta ttgaatgcat ctatcgacga tgcaaaccaa gaaatcgttt
    50881 ataaacatta ctacaatatc ggtattgcaa ctgatacgga tcacggacta tatgtaccaa
    50941 atgtgaaaga tgcagaccgc aaaggaatgt ttgctattgc agacgaaatc aatgagaaag
    51001 caaaattagc tcatgacggc aaactatctg cagaagatat gcgcaatgga acaattacga
    51061 tcagcaatat cggatctgta ggtggcggtt ggtttacacc agtcatcaac tatccagaag
    51121 tagctatttt aggtgtagga acgattgcac aacaaccaat cgtaaatgct gaaggcgaaa
    51181 tcgttgtcgg tcgtgtgatg aaactgtcat taagtttcga tcaccgtatc gtagatggag
    51241 caactgcgca acaagcaatg aataatatca aacgtctttt agctgatcca gagctattaa
    51301 tgatggaagg atgataaaca aatggtagtt ggagattttg ctgtagaatt agatacagtt
    51361 gtaattggtg cgggacctgg tggctatgta gctgccatcc gcgctgctga aatgggacaa
    51421 aaagtagcaa tcattgaaag agagtatatt ggcggtgttt gtttgaatgt cggctgtatt
    51481 ccttcaaaag cactgatagc tgcaggacac cattatcaag agtcactaga ttctgaaatg
    51541 tttggagtaa ctagtgaaaa cgtcaaacta gattttgcaa aaacacaaga atggaaagaa
    51601 aacaaagttg tccatacgtt gacttctggt gttggtttcc tattaaaaaa acataaggtt
    51661 gaaacaatcg aaggagaagc gttcttcgta gatgatcaca cactacgcgt cattcatcca
    51721 gattcagctc aaacttattc gttcaataac gcaatcatcg caacaggttc ccgtccaatc
    51781 gagattccag gatttaaatt cggaggacgt gtgttagatt ctactggcgg attagcattg
    51841 aaagaagtac ctaagaaatt tgtgatcatc ggtggcggtg tgattggtgc cgaattgggc
    51901 ggagcgtacg caaacttagg agcagaagta acgattcttg aaggctcacc acaaatttta
    51961 ccaacttacg aaaaagatct agtaaaatta gtagaagatg atttcaagaa aaaaggcgta
    52021 acagtcgtaa cgaatgcaat ggcgaaagaa gcagtcgata acggtgacag cgtgacagtg
    52081 aaatatgcag tggacgggaa agaagaatcc gttactgctg attatgtgat ggtcactgta
    52141 ggtcgtcgtc cgaatacaga tgatatgggc ttagaacaag cgggtgtcga agtaggagaa
    52201 cgaggattga tcacggtgga taaacaagga cgtacgaacg tacctaacat ctatgccatc
    52261 ggtgatatcg ttccaggggc ggcattagca cacaaagcca gttatgaagc aaaaatcgct
    52321 gctgaagcaa tctctggcaa aaaagtagct gtagattata aagcaatgcc ggcagtagcc
    52381 ttcactgatc ctgaattggc ttctgtaggt atgacgatca aagaagcaaa agatgctggt
    52441 atcgaagcaa aagcatataa attcccattt tcagggaacg gtcgggcatt atcgcttggt
    52501 aaaacagaag gattcatccg tctagttacg acgatcgaag ataacgtgct tattggcgcg
    52561 caaatcggtg gagtcggcgc aagtgatatg gtctctgaat tagctttagc aatcgaatca
    52621 ggaatgaatg ctgaagatat cgccttgacg attcatcctc atccatctct tggcgaaatc
    52681 gtcatggatg cttcggaatt agcattaggt ttaccaatcc atatttgatt tgaataatac
    52741 aggcgaaacg caactgaaaa atcagttgcg ttttgttttt tagaattatc aataatatta
    52801 ttatgtaaac ttaaaaatat gacaacttct tggtttatta ccacttccta tgctacactg
    52861 aagaggaata tgaaatagga gagttgaaga tgcaagaata tcagtatcca cttgatttag
    52921 attggacaac agacgaaatg gtcattgtaa tgaagatgtg ggaagatctg gaacgtgcga
    52981 atgaaaaagg gataaacaat gaagcttttt tgaagactta tcagcagttt aaaactgttg
    53041 tcaaatccat tggtgaggaa aaacgattgg gacgggaatt tgaaaaagct tccggttatt
    53101 ctttatatcg tacagtgcag caagcaaaaa aaaatccaaa caaaactttg agaatgaacg
    53161 ggtgagataa atggaacaga tgattgatca tatcaagtcc tggcttgaag aagctggtga
    53221 gaaaatcaaa tcttctcaac aaacattaac aatctcgcaa aaatcaaatc gaacggatct
    53281 agtaacaaat gtcgatcgaa acatccagaa ttttctaatc gaaaaaatcc attcctttga
    53341 tccagaggcg aaaatattgg cagaagaaga agggtgtaat caattatcgg atctcgatgg
    53401 aagagtcttt atcatcgatc ctattgatgg caccttgaat tttgtgattg aaggggaaaa
    53461 tttttgtatt atgctcgctg tttatgaatc cggcgttgga aagcttggtt tcatttatga
    53521 cgtgatgaga aatgaacttt tttggggtgg aaaaggaata ggcgtgtata aaaatgatga
    53581 gccattgcct agaccagcaa ataaatcctt atcggaaggc ttacttggtg tgaatagtta
    53641 tcttttcggt cataataaat atggaatccg agaaattgcg gaaagcagca tggggacacg
    53701 tatgtacgga tgcgctggtc ttgaactagt ggcaatcttg aaaggaaacc acattgctta
    53761 tatttcaaac cttagccctt gggattatgc agcgggaaat gtcttattgg aagagtttgg
    53821 tatggtaaca agcggtcttt ttggtactcc tttgacattt gaaaaaaggg aatactattt
    53881 agcagggact tcttgtgcat atgcagaaat cgcagacctt ttgaaaaaag aaggctgaaa
    53941 aaaaggtaga aatcattcac aaaaatgata aaaacgagca aaagattaat tttctcgaaa
    54001 aaatgaaaac attttactat atttcatgaa aaaagtctgc tataattagc agtcgagtaa
    54061 aatttgccct gtcataaaga accaataaaa aaggagttag ttacattgaa ttatagaaac
    54121 gatatccgta acgtcgcaat tattgcccac gttgaccacg gaaaaacaac attagttgat
    54181 gaactattaa aacaatcaga tacattagac gcacatacgc aattgcaaga acgtgcgatg
    54241 gactcaaatg cgctagaaaa agaacgtggt atcacgattt tagccaaaaa cacagctgta
    54301 gactataaag gtattcgcgt aaacatcatg gatactccag gacacgcgga cttcggtggc
    54361 gaagtagaac ggatcatgaa aatggttgac ggcgttgtgt tggtcgtaga tgcgtatgaa
    54421 ggaacaatgc ctcaaacacg ttttgtattg aaaaaagcac tggaacaaca tatcacacca
    54481 atcgttgtcg taaacaagat tgacaaacct tctgctcgtc ctgagcatgt cgtagatgaa
    54541 gttcttgaac tattcatcga attaggagca gatgatgatc agttagactt tcctgtgatt
    54601 tatgcatctg cactaaatgg tacgtcaagc ttgtcagatg atccagcaga tcaagaacca
    54661 accatggcac ctatttttga tacaattatt gaaaaaatcc ctgctcctgt cgataacagc
    54721 gacgaaccat tacaattcca agtttcatta cttgactaca acgattatgt aggtcgtatc
    54781 ggaatcggac gtgtatttag aggaacaatc aaagtaggag accaagtagc attaattaaa
    54841 ttagacggaa cagttaagaa attccgtgta acgaaattat ttggtttctt tggactaaaa
    54901 cgtctagaga ttcaagaagc aaaagctgga gacttgattg ctgtctcagg tatggaagat
    54961 atctttgtcg gtgaaacagt tactcctgtg gatcatcaag atgcgttacc tatccttcac
    55021 attgacgaac caacattgca aatgactttc ttagttaata attcaccatt tgccggtcga
    55081 gaaggtaaat tcgtaaccgc tcgtaagatt gaagaacgtt tgatggcaga acttcaaaca
    55141 gatgtatcct tacgagttga accaacaaac tctccagatg catggacagt ttctggtcgt
    55201 ggagaattgc atttgtctat cttgattgaa aacatgcgcc gtgagggata cgaattgcaa
    55261 gtatctcgtc cagaagttat tgaaaaagaa atcgacggtg taaaatgcga accgtttgaa
    55321 cgcgtgcaaa tcgatacacc agaagaatat atgggtagtg ttatcgagtc cttgagctta
    55381 cgtaaaggtg aaatgcaaga tatggtccat acaggaaacg gacaaatccg tttgacattc
    55441 ttaacacctg cccgcggttt gattggttat tcaactgaat tcctttcaat gacacgtggt
    55501 tacggaatca tgaaccatac ttttgaccaa tatctgccaa tgcttcctgg tcaaattggc
    55561 ggacgtcacc aaggggcgct tgtttcgatc gatacaggaa aagcaacgac ttattctatc
    55621 atgagtatcg aagaacgcgg tacagtcttc gtagaaccag gtacagaagt atatgaagga
    55681 atgattatcg gggaaaacag ccgtgataat gatttgactg tcaacatcac gaaagcaaaa
    55741 caaatgacaa acgtacggtc tgctactaaa gaccaaacat ctgtcatcaa aaaaccaaaa
    55801 caattgacgt tggaagaatc tttggaattc ttgaatgatg atgaatattg cgaagtaaca
    55861 ccagaaagca ttcgcttgag aaaacaaatt ttagagaaaa atgctcgtga aaaagcatct
    55921 aaaaagaaaa aataatctgt aaaaggatga agagagaaac cagcttgtta taaaaaatag
    55981 ctggtttctt tttttgtcca actcttttct gtggagaagt catctttgtc aatggacata
    56041 aattcagaaa atacgccgaa aggcgtttaa aagactttta aaaaacttat ttctagagag
    56101 tttttgtttc ataataagat aatgtttcac gaaaggagat caacttgtcc ttcgaagaaa
    56161 atcgaagtaa aatggcaaga gaaaggagcg ggaagatgaa cgacttatta aaacaatact
    56221 ttggctatga tgagtttaga cctggtcaaa aagaaattat ccagaaagtc attgatcagg
    56281 aaaatgtatt aggaatcatg cctaccggaa gtgggaaatc aatctgttac cagcttccag
    56341 ctttactatt agatgggctt actgtggttg tgtccccttt aatctctttg atgaaggatc
    56401 aggtggacgc ggcgaatcaa ttaggtatac ccgccacttt tatcaatagc tcgttagatg
    56461 gttacgaaac agctagacgc ttccaagaaa tcgatagaca gcagtaccgt ttactttata
    56521 tcgctcctga acgttttatc atgccggatt ttatccaagc aatgaagcga tggaacgtcc
    56581 gtatgatcgc tattgacgag gcacattgta tctctcagtg ggggcatgat ttccgcccaa
    56641 gttatttaca gatggcgaac cagctagatc aactgccaaa tcgtcctgta attgttgctt
    56701 tgacagctac agcgactgtg caagtagctg ctgacataaa aagactttta aaaattccag
    56761 aaaacaacca tattcagact ggttttgaac gagaaaatct acgatttcaa gtaattaaag
    56821 atcaaaaaaa agaacaatat ctaatcgaat atttaaagat caacaaaaat caatctggta
    56881 tcatttatgc agcaacgaga aaagaagtag accgtctcta tcatttgctt aaaaaattcg
    56941 atttttccgt gggtagatat catggtggtc taaatgagaa tgagcgaaca gaaatgcaag
    57001 aagccttttt atacgatcgc ttgcagctga ttgtagcgac aaatgcattt ggtatgggta
    57061 taaataaaag caatgtccgt tttgttatcc attatcaaat tcctggctct ctagaagcat
    57121 actatcagga agctggtcgg gcgggaagag atggtctttc cagtgaagcc atcctgcttt
    57181 tctctcctca agatatccaa gtccaaaagt tttttatcca gcagtcccaa agagaagaag
    57241 ggcaaaagca aaaagaatat gaaaaattaa aagcgatgac agaatacgtg tatattgagt
    57301 cctgtcttca gcaatacatc ctaaactatt ttggcgagac aagcagtccg tgcaaccgtt
    57361 gtggtaactg tttagatgac agagaaatag tagaagtaac gacagaagca cagatggttc
    57421 tttcttgctt aaaacgtatg ggtgagaact atggtaaaca aatgctgatg aaagtcttag
    57481 caggatcgaa agaacaaaag ctgcaagctt taggttttgg acatttatct acctatggac
    57541 tgatgaaaaa ccaatcgcaa aaagaaacga tgcagttaat tgaatatttg atatcgaatg
    57601 gctatcttct gaccatcaat ggtgagtatc ctgttttgaa agtaacagaa agagggatac
    57661 aagtattgaa aggacaagaa tctgtttatc gaaaggaacc caagaaagtc cagcagctat
    57721 cggatgaaga aaccgataca ctatttgaag tgctgcggga actgcgaacg gatctagcat
    57781 cagaagcagg cgttcccccg tatgtcgtat tttcagattc cacattgaaa gaaatgagcc
    57841 gaatacgtcc atcaagcaga ttggagatgc ttcagataaa aggagttggc caaagcaagc
    57901 ttgataaata tggcgaagcc tttttatctc ggataaaaaa tgcggactct aacgttctgg
    57961 ataagtagaa agaacgaata cgtaaaaatg aataaaaaca actggttaaa tctgtttttt
    58021 ttgctcctta tgaaaatcaa atatgttata attaaggaat tagaatggga ggtaagcaca
    58081 gatggattct ttgtcgaaaa aacttgcgat ccaagtatta aatgatgaag cagaacggat
    58141 caaacgatta atccgaaatc aaaacaacag tctctgtatc tcacaatgca aagccttcga
    58201 agaagtggta gatacacaga tgtacggctt ttcccggcaa gtcggttttg ctgtccgtat
    58261 aggagtaatc ggaaagaacg agggccagct gatgttaagt gagctagaac gagaattgaa
    58321 tcagttatat agtgaggttt accaagaaat ttatgataaa aaagaagttg gcaaggagga
    58381 atagacttgc ctaagaaagt gaaaaaaagg catctattag actatagcat cttgattccc
    58441 tatttaattt tatgtgtatt gggattgatc atggtatata gttctacgtc gtatctatta
    58501 ttagaaaacg gacaaaatcc gtccgcatca gtcattaacc agagtatttt ttgggtgctt
    58561 agcttgattg ctatcgcact actttataaa atgaaaacag atgttttgaa aaaccagcgt
    58621 ttgatcatgg cagccatcgc agttttgacg attttgctgc tgattgttgt gttttttggt
    58681 aaggagatca atggggcgaa aggttggctg caaattgcag gattctcgat ccaacctgcc
    58741 gaatacctaa aaatcatttc tatctggtac ctgtctctga ctttatctaa aagacaaaac
    58801 agtgtacaaa aagattttct tgggactgtg aaacgtccac ttgcaatggt tatcggactt
    58861 actgcattag tcgctattct tcccgatttt ggtaatgcgg cagttatctt tttgattatt
    58921 ttggttctgc ttttagccag cggagtcaat tatgtgtata ctttgattgt aggagtagga
    58981 ggcttttgtc taagtacttt tacgatctgg ctgatcaata tcacaaacgg aaagatctta
    59041 cccggacgtt tacagtatat ctataatcga tttgctattt accaaaatcc tttctcagac
    59101 gaattaaata aagggcatca actagtcaac ggctactatg ccatgttcaa cggaggacta
    59161 tttggcaggg gattaggtaa cagtatccag aaaaaaggat ttttacaaga agcacaaacc
    59221 gattttattt atgcaatcgt agtggaagaa ctgggagtga ttatggggat tttgatatta
    59281 gcgttgctat tctttatgat tgtgcgcatt gtccttgtag gtatccgttc aaaagatccg
    59341 ttcaattcgc ttttgtgcat tgggatcggc gcaatgtttt tgatccaagt atttgtcaat
    59401 cttggaggaa ttactggcgt tattcctttg acagggatca cgttcccatt tttaagtcaa
    59461 ggaggctcca gtttgctgat gctttcgatt tgtgtcggct ttgtcctcaa catcagtgcg
    59521 gatgaaaaac gcaagagctt aggtttataa taaaaaaaga tgtaggagtg gttcgatgaa
    59581 aaaagtttta gttgctaaca ggggtgaaat cgctgtacgt gtatttcgtg cttgtacaga
    59641 attaggaatt aaaactgttg gaatctatgc agaagaagat gaatattccg tacaccgttt
    59701 caaagcggat gaagcatatt tagtaggaca aggaaaaaaa ccgattgatg cgtatctaga
    59761 tattgaaggg atcatttcta tcgcgaaaga atgcggagct gacgctattc atccgggtta
    59821 cggtcttttg tcggaaaact tgaattttgc gcaacggtgc gaagaagaag gcatcatttt
    59881 tgttggaccc aaactgcatc atttagatat ttttggagat aaaatcaaag caaaagctgc
    59941 agctatcgaa gcggggattg cttcgattcc aggcacagat ggaccaatcg cttctataga
    60001 cgatgccttg gagtttgcga aacaatacgg ttatccgatt atgatcaagg cagctctagg
    60061 cggcggcgga cgcggcatgc gtgtagctca cgatgaaaag agtgcaagag agggctacga
    60121 acgtgcgaaa agcgaagcaa aagcagcctt tggtagtgat gaagtgtatg ttgaaaaata
    60181 catcgctaat cctaagcata tcgaagtaca gattctcggg gatacgcatg gaaacgtcat
    60241 ccatcttttt gaaagagatt gttctgttca gcgccgtcac caaaaagtag tagaagtagc
    60301 gccttgtgtc tctatgaatg aacagcaacg tcaaaaaatc tgccaggcag ctgtccaatt
    60361 gatgaaatat gtcgggtatg tcaacgcagg tacagtagaa tttcttgttg aaggagatga
    60421 tttttacttt atcgaagtca accctcgcgt ccaagtggaa catacgatca cagaaatgat
    60481 tacagatatt gatatcgtaa caacgcaact gttgattgct caaggtttgg atctgcataa
    60541 agaaatcgga ttgcctcagc aagaaggaat taaattaaat ggttcagcca ttcaatgccg
    60601 aatcactaca gaagacccgt tgaataactt tttaccagac acagggaaaa tcgatacgta
    60661 tcgttcacct ggtggttttg gcgtacgtct ggatgtcgga aatgcttacg cgggctatgt
    60721 agtgacaccg tattttgatt cattgctagt aaaagtatgt acgcatggtg ctacctttga
    60781 aacagccatt cagaaaatgg aacgttgctt gaaagaattt agaatccgtg gagtgaaaac
    60841 aaacattcca tttatgctca atgtcatcac acatcctgaa ttccaatcag gaaatgcaaa
    60901 aacaaccttc attgatagta cagcaacatt atttgaattt cctcgactac gagaccgcgg
    60961 aaacaaaacg atgaaatata tcggtgaaat tactgtgaat ggttttccag gtatcgaaag
    61021 tggcgaaaaa ccattttatg aagaaccacg tatgcctaaa gatctaatca caagaactga
    61081 ttacgtaacg gctaagaatg tattagatgc gaagggtgcc gatgctttgg tcgaatggat
    61141 caaaggacag gaaaatttgt tgttgacgga tacgacattt agagacgccc atcaaagtct
    61201 gctagcaact cgtgttcgga caaaggattt caagcagatt gcacgtttga ctggagaagg
    61261 tcttcctgaa ctcttttcaa gtgagatgtg ggggggagca acatttgatg tggcttaccg
    61321 ctttttgaat gaagatcctt ggcaacggtt gagaaaaatt cgttctttaa tgcctaatac
    61381 gttgctgcaa atgcttttca gaggttcaaa tgccgttggg tattctaatt atcctgacaa
    61441 tgtattggtg gaatttgtca aagaagcagc agcgcaagga atcgatgtat ttcgaatctt
    61501 tgatagtttg aactggactc cacaaatgga aaaaagtatc caagctgtac gggatactgg
    61561 taaaatcgca gaggcagcta tttgctatac tggcgatatc aacgatccaa gtcgggcaaa
    61621 atacaatgtt cagtattata aagacatggc aaaggaacta gaacaactgg gtgcgcatat
    61681 cattgcaatc aaagatatgg ctgggctgct taaaccgcag gcagcttatc gtttgattag
    61741 tgaattgaaa gaaacgacag atctgccaat ccatctgcat actcatgata ccagcgggaa
    61801 tggaatcatc acttattctg ctgcttcaaa agcaggagta gacatcgttg acgtggcaat
    61861 gagtgcaatg agtgggaata ctagtcagcc tagcatgagc agcttgtatt atgcactggt
    61921 caatggtcca cggctgccag aaatcacgat tgaaaatgca cagaaattaa accattattg
    61981 ggaagatgtg cgcatgtatt acaaaccgtt tgaaaacggc ttgaatgctc ctgaaacaga
    62041 agtatatatg catgaaatgc caggaggaca gtattcgaat ctacagcaac aggcaaaagc
    62101 tgtcggatta ggtcatcgct gggatgaaat caaacaaatg tatcatactg tcaacttgat
    62161 gtttggcgat atcgttaaag taactccatc atctaaagta gttggagata tggcactatt
    62221 tatggtccaa aatgatctta cagaagaaga tatttatgaa aaaggcgaaa cactaagttt
    62281 ccctgaatct gttgtgactt tcttccaagg agaactaggg caacccgttg gcggatttcc
    62341 taaaaaattg caaaagatta ttcttaaagg cagacctgca ttgaatgaac gtccaggtct
    62401 tttggctgaa tcagtcgact tcaacgaagt aaaaaaagaa ttggcagaaa aaattggcta
    62461 tgaaccaaaa caagacgaag tattaagcta tttgatgtat ccgcaagtct ttttggacta
    62521 tcaaaaagca tataatcaat ttggcgatgt tacattactg gacacaccaa catttttcca
    62581 aggtatacgt ttgggtgaaa caatcaatgt acaaatcgaa cgcggaaaaa cgcttatcat
    62641 tcgtttagat gaaatcggag aacccgatat cgaagggaat cgcgtactgt tcttcaattt
    62701 gaatggacaa agacgtgaaa tcactatcaa agataattcg atcatcagta cggtccaaac
    62761 ccgattgaaa gctgaaccga caaaccgaga acaaattgga gcaacgatgt ctggttctgt
    62821 tttggatgta ttagtgaaaa aaggcgataa cgttaaaaaa ggtgatacgt tgatgattac
    62881 tgaagcgatg aaaatggaaa cggccatcga agcacgtttt gacggagaag tcgcacatgt
    62941 atatgtgtct tcaggagaca ctatttcgtc tggtgacctt ttgattgaag tgactgagaa
    63001 ataataagcg aaaggtgggg aaacatgaaa agactgggtt tgttttggct gattctgcta
    63061 ttagttattg tggcattcta catggaacca gtcttgtttc cgccaaaact tgaagtgaag
    63121 gaaaactctg atcaacaaat atcaaaccaa atgacaacgt ggaaatacca ggagcttaaa
    63181 gcaactggtt tttctactta tatcggaaaa ccgatcgatc agctggaaaa ggattttggc
    63241 caagcctatg atcgattaac tagcggattt ggttttgaaa caagatatta tgaaaataaa
    63301 gctagtcatc tcacatttga agcgaacatc caagacagca gagtcacaac tgttaaagta
    63361 ctgcaaacag ggcctgctga tatcgcgccg ttttatttag ggatgacgat gcaagatctt
    63421 acgaaaatca ctactatcta tactaatttc acttttgagt accatgatac agaagttgga
    63481 atcgaactaa tggaagagga tatgaattat cgtccgctaa ttgcttttga taacgacact
    63541 tttgctattt tattttttga tcaaacaaca aacggcctat tttcagttgt gtatttagat
    63601 aaagatagtc ttttgaaact attgccatat caagtgtttg gtgaaggcct tccacattat
    63661 caagcagata aatcggctga ttgggaatca atcaatcgcg ttaaagaacg aaaaagtacg
    63721 actttattaa atatgcttag aagagaagac gaacttccca tatacaatca aacacttgcc
    63781 tttcaaaacc acagtcagct gctactacat gattttttga caaggcctga ggaaatattg
    63841 tcagaggaac gtatggctga ttggcaaaaa tcgctaggca gtgctcaaac gacagtgaaa
    63901 ttctcactga cgaatgatga attggagaag ttaatcagta aacaaaaatt agaaaatact
    63961 agtgggctat ttattcatcc ggcgattgac gctacttttt cgtttttata ttggtacagc
    64021 gatccttaca accatgaccg tttcatggac ccgggaacgg attctgtagg cattgctttt
    64081 tctaaagaaa atatgttagt cttattgcaa gaagaaaacg gagaaagtag tgatagcagt
    64141 gatcgttaac gaagagctgt ttcaactgga ggatcaatgc ctccaagtcg ctgaaatgat
    64201 aaaaaagagt aaaacgatgg cttcttatct tgaacataaa cagtcaatgg aagaatctgc
    64261 aaaagtttgc cagttgaaag aagcgttctt gtctaagaaa gaagcatttg aaaatgtagc
    64321 ggcatatggt gagtatgcac ctgattatcg tgaaaaaaaa cgagctgttc gaaaagcaaa
    64381 aagacagctt gatatggatg agcatgttgc agctttccga tatagtgaaa cacagctgca
    64441 aagtctgttg gatcaaattg tccaagtact tgccgaagaa gtttctaatg aaatcaaagt
    64501 agatgcaggt agcccgtttt ttgaaacgaa aaaacacttt ggatgcggag gtaattgtca
    64561 tgcaattaga caatagtgaa tttgaaataa caaaacgacg cgggctgatc gtatgggtct
    64621 acagcttaaa acaattaaag aatctgaaaa agttcggctt gttgcattat gtctcaagaa
    64681 gaatgaaata tgtcgtgctt tacttaaatg aagagacatt ggaagaaaca gaagaacgaa
    64741 tccgtaaatt acattttgtt cgaaacgtag aacgttctta ccgaccggat atcgaaatga
    64801 attttgccga aaaaatagga aacaaaacag tattaaaaga cgaaggtttc gaaattgaag
    64861 agctaaatac agaaatccga ttagctgaac atctttaaaa atctcttatg agcagttttt
    64921 aaataaaaaa taacttggat aacgatcgat ttttgatcat tgtccaagta tttttttggt
    64981 atactagtac cagtaccatt tctaaggagt gagtagatgc ggataatatc aggaaattat
    65041 ggcgggcgcc gtttaaaaag tttagcaggg gcgaacacca gaccaactac agataaagta
    65101 aaagaatcca tattcaatat gattggacca tattttgatg gagagacagt attggatctg
    65161 tttgcaggaa gcggtggttt agctatcgaa gcagtatcta gaggctgcag tcatgcggta
    65221 tgcgtagaca aaaattacca agcgctaaaa atcatcaaag aaaacatcga aattacgaaa
    65281 gaaccagaga aatttaccac aataaaactt gatgcggaca aagcaatcga acggctagca
    65341 gcggagaaac aacaattcga ctacttgttt cttgatccgc catatgcaaa acaaaaaata
    65401 atcgatcaaa tccataaaat ggaagaactg ggactttttt ctaaaaccgc agttatcgta
    65461 tgcgaaacgg ataaaacagt cgaattgcca gaaactgtgg ctggattcca tcaaataaga
    65521 aaacagattt atggcataac ggccgtaact atctatagaa aagagggaaa tcaatgaaac
    65581 gtgcattatt cccaggaagt tttgatcctt ttacaaaagg tcacttagat acggtggaac
    65641 gtgcggctaa attattcgat gaggtagtaa ttggtgtttt tatcaatact tcaaagaaaa
    65701 gtttgtttcc cccagaagaa agaatgacat tgatcacaaa agctgtttct catcttccta
    65761 atgtaaaagt catgcatcaa gaaaatcaat tgacggtaga aacagcaaaa gagattggtg
    65821 cagatgcgtt gatcagaggc atacgaagta tcaaagactt tgaatatgaa cgagagattg
    65881 ctcagatgaa tcatcatcta tatgatgaat tggaaactgt cttcttatta gcaaaaccag
    65941 aatatagtca cgtgagttcc agtattttaa aagaagtact gcactttggc ggagatgtga
    66001 gcagctactt accgccagtg atcaacgaag ctttagctgg aaagcgtgaa tcaaatgaaa
    66061 gctaaacaat ggttgaaaac agtactgatt atcatatttg gaatgttgat cattggattt
    66121 gtagtagttc ccttgccgta ttatgtagaa tcaccgggag ccacgatcga tctgaaagaa
    66181 ctaattacgg tcaatgataa ggaagataaa ggttctgggt ctttctctct tacctctgtt
    66241 ggtatcaggc aagctacagg tttcttagct ttaaaagcta aaatgacccc ttttgaagaa
    66301 ttgatcagtg aagaagaatt gactggtggg gcgacaaatg aagaatataa tcaaatgcaa
    66361 cagtattata tggattcttc ccaaaatgca gcaatcgaac aagcgttaaa acttgcagac
    66421 aagccttata aaatggaatt caaaggcgta tatgtcatga gtgtagagaa aacatcgaat
    66481 ttctttggca agctttcagt tggagataca gtaacaaaag tagacgggaa aagctttcaa
    66541 agtacagaag catttatgga ttatgtaaaa agccaaaaag ttggacaaac aatcgaaatc
    66601 agttatttgc ataatggtga agaaaaaaca gcttctggtg atctgatcga gttaccaaca
    66661 gataaaaagg caggaatagg tatcacgctt actgaccata ccgagatcga atcagataca
    66721 gatgttcgta ttaattctgg ctctatcggt gggccatcag cgggattgat gttcacttta
    66781 gaaatctatg aacaagtcac tggtaaaaac ttgcgacatg gtaagcaaat tgcaggaact
    66841 ggaacgatca acagtgaagg agaagttggc cgaatcggag gaatcgataa aaaagtggca
    66901 agtgcggata aagctggcgt agagattttc tttgcaccag atgatacgat ttcagacgat
    66961 gttaagaaag aatatcctga aataaaaacc aactacgaag aagcaaaagc tgccgctaaa
    67021 aaattgaatt cctcaatgaa aatcgtacca gtaaaaacag tacaagaagc gcttgactat
    67081 ctagagaaaa tgaaatgaaa ctaaataatt aaagaggggt tgtgacacga gttctgtcac
    67141 aacccctctt tttcgtcaaa aatcttcacg ataaaaataa aaacaaaaga aaaaattgac
    67201 gtaattagat gttgaaggga cgattttgcc agagctcact gtttcttcaa ttttaaatga
    67261 aaggagtaat gaatgatttt tactggtcat tctttgaaaa aagaacaatg atagaaaaaa
    67321 tcagcaagaa aatactagct tcacccaaat tgatcatttg gatgtctatg atagttctta
    67381 tcttttgtat cgcaagtggt tttttattat caaatttgct attttataga gaaacagaag
    67441 agactgctgc aaaagaaata ctttcttcgt ttagttccag tggagaagat ccatcagctg
    67501 aaggaaacga tgtagaagag gatgctcgtc caaaggtcat gtacaccgat atcaaaggaa
    67561 gtgtgaagga gcctggtatc tattcctttt cttcagaaga acgggtctat gatgtactaa
    67621 agcgtgcagg tggattatta gaagaagcgg atagcgatcg aatcaacttt tctgcgaaga
    67681 tagaagatca gcaagtccta tatatccctg ctgtaggtga agagctgcca gaacatcttg
    67741 atcagttggc atcctcggaa ggaaaacagc ctacagcaga ttccgagcct cccaaaataa
    67801 atatcaatac agccactcca tcagaacttc agcagattcc tgggatcgga tcagtcaaag
    67861 cgcaagaaat cattcgattt agagaagaaa acggatcctt ccagaaagtg gaagacctgc
    67921 aggagatttc tggtatcggt gaaaagacag ttgaaaaact aaaaaacttc gttacaatta
    67981 aatagaatga ttcaaaatcg actggcacga gcaataaatg gacgctaatg gatactaaga
    68041 ataatccaat tctaagagct tggcaggacg aggaggtagt atttttggat aggaaatagc
    68101 ttgattgttc gcaaagaaac attaaaaaaa ccaatgctga atgtctatct ccaaaataaa
    68161 atatctggga ttcatattat gaatacggct gtcagcggca ataacagtca agctctacga
    68221 gaacgctttg ccaaagatgt acttagctat acagcagata aagtatttat tctcattggg
    68281 acgaatgatc tagcagagca taaacaactt tctaaagaaa cgtaccaaaa aatctgcagt
    68341 ggatgatagt tcagctgaaa aaagactata gttctgatca tgctttcttt atcacgccac
    68401 cagcagtcga tgagacaaaa caaaaatatc ggaataacaa gttgatcaaa gaatatatct
    68461 ctgttctcac agaagtagca aaacgccatg attgtgaagt atcgattttt atacggaatt
    68521 tcttgaacaa atggattcga agaattttta taatgggcta atggatgacg gacttcattt
    68581 cggcagtgaa gggtaggatc ttttgtcaga caggatgatt cgttatattt aaagaatatt
    68641 ttgtttaagc aatgagtact ttttaatcaa cttgaaaaaa cggaggaata taaaacatgt
    68701 tagaaaaatc ttcaaaagca tgcgatacga ataaagaaaa agttactgat aagtcacata
    68761 atgaacgcat tccttgggac cagtacttta tggctcaggc agtactgtta tctttacgta
    68821 gtacgtgtac acgtttagaa gtaggagcga cactcgttcg agaaaaaagg atcattgctg
    68881 gcggctataa tggagcagtc agtggagatg tccactgcat agatgaaggg tgttacgtcg
    68941 tggatggaca ctgcttgcga acgatccatg cagagatgaa tgcactccta cagtgtgcaa
    69001 aacttggtat cccgacggaa ggttcagaaa tctatgtcac acattttcca tgtttggcct
    69061 gtacaaaggc tttgttgcaa gctggtgtga aagggatcaa ttatctccat gactatcgaa
    69121 atgatcctta tgcccaagcg ttgatcgaac aattaggtgt atctgtacac caagttgctt
    69181 tagactcaca gcatttttca aaacttcaaa atgaattaac aggaaaacat gtctagcgtt
    69241 ttagaaaggc atgttcgaaa tcggttgatt tttccggcaa ttacgtcgat gattatctgt
    69301 ttgttgtatt acactgacaa ttggggttat cgtttgcttc ttgccggaat ttttttatgg
    69361 ttttcgctaa aagaaggacg ttttatcgcg tacttgtgta ttttgtgtag cataacggta
    69421 tccatttctt ataggctaca agagtattca tttttagagg aaaaaacaac atctgcgcaa
    69481 attactgtat ttacagatac gattcgtgca aatggtaatt ttttgacaat ggaaggaagg
    69541 ttatcagaga ataaacaaaa gctccagctt tcttatcaag taaacacaga agcagaattg
    69601 aaaacatggc ttaacttccg aggaaaggga atagaattga ctgctgaagg cgagttcatc
    69661 tctccagcaa aaaagcggaa tctttataat tttgaccaag aagcttactt caggaaccat
    69721 agaatttctg gacggttcca aattcaaaag attgaacaga tcaccatgca aaatcactgg
    69781 cgaaactggc ttcagagaaa aagaggatct tttatctcct ttgtccaatc tgaatttccg
    69841 caaaaaacaa gtgtatatat taattcttta ttatggggct ataaagatgc aggattcaga
    69901 gaaccagaag aaatttttag ggagagtggt ttgctgcatc tgttcagtct atcgggtcta
    69961 cacatccaat tttatttagg gtggctgtat tatttatttc gacgtatcgg atggccacta
    70021 cacgtcagta ttattccgtt gagtctacta actatctgtt atgtttctat tgcaggaagt
    70081 tctatttctg ttttgcgtgc tagtttgctg tttttattgc gattgctagt caaattgctg
    70141 aataagcatt attccaccat ggacttattt gcagttgtct tttggcttct tttactattt
    70201 gatcctcgat ttctttttca tgcgggtgga cagcttagtt ttttcatgag ttttttgttt
    70261 atcctgattt cttttgatgg agattggttg aaaaaaacgg cctctcacgt cctgtttact
    70321 atgatcacga tgccgttgat tgtatggcat ttttatgagt ggcctatttt aggtagtctt
    70381 tttacattac tgattgcacc ggtattcaag tttctttttc ttcctggtgt gttatttctc
    70441 acactcttca atcgctggct gccggaaact ttacttttgt tgatagaaga gggattaatc
    70501 ttatttgagc gaataatcga tttttcttca gggtcgtctc tcattatagg acgtttgccc
    70561 cttgtgctat ctgggatgta tattttcgga ttactgattt gtatggatag gttgaaagaa
    70621 caacctgtga aacacttgtt ttatgttggt cttttttctt ttattttttt gactttgcca
    70681 tttttacgct tttcttcaac gatcgctttt atcgatgtcg gtcaaggaga cagtatcttt
    70741 ttgcaaagtc cttttcgaaa agaaacgatt ttgatcgata ctggaggtca gttacacttt
    70801 gaaagagaaa agtgggcgca aggtatgata cgtcctcctg ctgaaagaaa tatcgttcca
    70861 tatctaaaag gtcaggggat aagtgtaatc gataaactca tcttgacaca cgacgatacg
    70921 gatcatgtgg gagaattacc cacgttatct cagcatttta ctatcaaaaa aatttatatc
    70981 ggttggggcg ctggacgaaa tgagccatta caaaggcatt tatctgaagc tcaaaaaaat
    71041 ggtactgaga tcattgaaat caaacatggg gacaggatca gcggttatta tgatctttat
    71101 gtattgactc cttttgaaaa gggagaggga agaaatgaag attcgattgg tctatggatg
    71161 gaatataaca ataggcgctt tttattttta ggagatttga atcaagcaat ggaaaaacaa
    71221 ttgcttttga tttatcctaa tctgaaagcc gatgtagtca aattaggtca tcacggtagc
    71281 cgtacgtcaa gtaacacaga ttttctttcc catattgaag caaaacatgg gattatatcc
    71341 tgcggcgtaa ataatcgtta tggtcacccg cacagcgaag tattggagac actagaagaa
    71401 aatcagataa aaacatggcg aacggatcaa caaggaatga tcacctatcg ctggcatcca
    71461 gtttttcatc ctcatgggct agtggaaaca atgatagact agtaattctc atctgctcat
    71521 ggtaggataa tttttgaaag tggtgagtaa tttgagtata caagcagagt tacaaaaaat
    71581 acgtaaagaa aaacttgcat cttgttactt gattttagga acagaaaagt ttctccaaga
    71641 tcaagttcgg acagaaattg tcaaaaaaat ccaattagag ggcgaagatg acttaaattt
    71701 tttaagtttt gacatggaaa atgcaagttt agatgaggta gtagctgaag cagagacgtt
    71761 gccgtttttc ggagatcaac ggttagtatt cgtagagaat ccttattttt taacaggtga
    71821 aaaagtaaac aatggaatcg aacaaaatac tgatttattg acggcttatt tgaaagaacc
    71881 attagaatcg actgtattag tattctttgc gccatatgaa aagttggatg aacggaaaaa
    71941 agtaacgaaa caattgaaaa aaacagcaat tatcatcaat gtccaacagt tgaatgaaaa
    72001 agaagtacgt caatatctga tgaatacctt agagaattcc tcaatcaaaa tggaacgaag
    72061 tgcaattgat ttattcttga ggttgaccga cttagattta tccaaaatga tgagagagtt
    72121 acagaaattg gtcctttatg gacaaaatca acagcaaatc acggtaagag aagtagaaga
    72181 attagttcct aaaacgttag aacataatat ttttgacatg acccaatata ttttaaaagg
    72241 gaagacggaa caagctttgc gtttatacga agatttagtt atgcaagggg aagaaacaat
    72301 caaaattaat gcgattttgc tttctcaatt acgtttattt ttacagacaa aatttcttgt
    72361 aaagattggt tatcagcagg caaatattgc tgaaacattg aaaatccatc catatcgtgt
    72421 aaaacttgcc atgcaggaag taaaaaaatt cgatgaacat ttgctggtac agttgtttga
    72481 tcaattagtt gagatggatt atcaaatcaa aacgggacaa atcgaaaaag aattaagttt
    72541 tcaactattc gttttgcgca cagggcagtt gttaagaaat cgataagaag aaagacgagg
    72601 gcaaagcatg cgggaaggtc gtttgttttt gtcctttttt tgacaaataa aaaaatcggc
    72661 cgaagccgat tcttttattt agcgattttt ttgcttaaac gagatttgtc gcggttagct
    72721 ttgtttttgt ggattagacc ttttgattca gccatatcaa tagctttaac agcttcttta
    72781 tataacgcat ctacgttgtc agcacctgaa gctacagcat cttcaaattt tttgattgca
    72841 gtacgcatag cgcttgtttg agatgaattt ttcacattag cgttttcgct tgtacgaaca
    72901 cgtttgattg cagattcaat gtttggcatt agtttcacct ccgataactt aagttcttac
    72961 gcgtgttacc gcataattca acattcatta ttatacctaa aggcagcgtg ctttgcaata
    73021 tgaacatgac aagttttttt ccttaacagt cttttattag gatttttttt cagtaaaaac
    73081 ggatagtaca agctgaaaaa aatcaaaaag acgctattgt gggaggcaat agcgtcaaac
    73141 caaactagat ttttatttat ctatttaaac aaagtttgaa tgggaatgtt tggtactaag
    73201 ttattatata acaaagagaa ccgtttgcaa agtttttttt gaaaagggat acgattccct
    73261 gttgttcttt gtttttctat taagaaactg cagttatttt ataaccagta tcctttgatc
    73321 agtaaaggct attctggtgt accgattatt ttaatgtatt catcgatatt ttttatcaac
    73381 atttttttta tgaccaactg gttccgacgg ttccatttgc cacttacttc cagcacatat
    73441 ttatttaggg gcaaacgtaa gatatatttt gccaaatagc gatctttaag caggccattg
    73501 atcacacggt cctcaagctg caagttgatc ccagtcagca tcattggctg ttcttgtaaa
    73561 acgtacgtat caattaaaag accttcaaaa gtttccacaa gcgtcttcct ttcttttcaa
    73621 agtaacctga aaacaggcac taattcttcc attttgatat tcgttgaagt ggatgcgatc
    73681 attctttctt ttgtccactg taatctagta taacaaaaaa gagcagaaga gccaaaaaga
    73741 aaaaagagca tcgaattcta taggaagtct cattggcacg gcctaaatta ttacaaaaca
    73801 ttgattaaaa aaagcccctg catcgcagga gcatccccta tatcgtttta ataggtcaat
    73861 caaaaagcag tatcaaacac attttgtatc aaatcaggaa ataatagata agctaagccc
    73921 agaatcaaaa gtaccgctag aagaaaccag ccgattgttc ctatgaaata ctttaatttt
    73981 tcgaacattg tatcacctcg ttgtcagtat atcacggatc agtaaattgg gggtgttaag
    74041 aatctcctaa aatagacaaa atttgttcta ttttcctaaa gcaaatactt gtaagataca
    74101 gtaagtgata ccagaagcaa tgaccggtcc ggcggcgatt cctcttaaga agacaacacc
    74161 taaaatcgtg ccgaaaacaa gtgcaacagt gatttgtgga tcagaagcaa tcaatcctac
    74221 acccttggaa gataagacag ccactagccc accgcaaaaa acagctaccc agccaatagg
    74281 ggatttaaag gcttctaata gatcacgtag accgatttct cctgttgcga tagggattag
    74341 aatagccgct gtgatgatcg tcaccccaat attgattcct ttgccttgaa gccaagggaa
    74401 aaaggaacgg gaggctggta tgagcttcat aatcaaaaca aaagctgccg ctatcatcag
    74461 actttgattt ttagctaaaa ttgctacaag taaaataatt cctaaaaaaa gccaactttc
    74521 catgaaatat attcctcact ttcttcgaaa caatcataac atgtttttag aaagttacaa
    74581 aagtaggaat tcatccttca agacctattc ataagctgtt tttttcataa aataaacaaa
    74641 atcataaaaa aacactttgc ttatttgaca gaagacagcc gcgctttgta tagtggacaa
    74701 gacttacatt tttttgaaga atcagaaaga tcaggtaaag gtcttagtaa acgcaagcca
    74761 ttcagaataa ccaatattgt gcttccttcg tgtcctacaa ctccaagagg tagatttaaa
    74821 aattgcagga agttagaagc aatcaacaag agaataacaa gaatcgaaaa aataatattt
    74881 tgtttgatga tccgccgcat ttttaaagat agccgatgac tgtagacaaa tttatttaag
    74941 tcgcttttca ttaagacgat gtctgcgata tccatagcgg catctgtccc ttgccccata
    75001 gcgacaccta aagaagcggc tgctaaagca ggcgcatcat tgactccatc accaaccatc
    75061 gcatttactt ggtaaagttc attctctttt ttgactagtt gtgttttttc ttccggagta
    75121 cagcttgcat agtaatgttc aatccctact tgttcagcaa tggcctttgc tgtgccagaa
    75181 tggtcgccgg ttatcatact tgtatggatg ttttgggatt taaagtagga aattacttgt
    75241 tgggtatttg cttttggaat atctagcaga cctaaaacag caattaactg ctgatcttta
    75301 gaaagataaa tcacggtttt gccttgattt tccaaacgtt cgatcatttc cgcaatctct
    75361 ttgctgatta tcatcgtctc aggatcatat gcgtgcttgc caactttcca ttgcgcacct
    75421 aaataggtag tttgtaatcc aaaaccagta atttcttcta ttggtaagta ttggatttct
    75481 tcaggtattg tgcaatcgaa atattgcaaa atcgcatgag caagtggatg cgtcgttttt
    75541 tgttccatag caacaagaag ttgttgtgcc aaatcctttt catcaaagaa aaagctgtca
    75601 gttacaactg gttttccttt agtgagcgtt cctgttttat caaaggcaat cgcttttaat
    75661 tcagaaagct tttctaaatg gataccgcct ttgattaaaa tcccattttt tgcagaattt
    75721 gaaagagcag ctagagaagc tggtgtagca gatgcgacaa gcgcacaagg agaagccaca
    75781 actaataata ccattcctcg ataaaagctt tcatcccaac tccaacctag gaaaaagtgg
    75841 gggagaagga tcattagagg aacagcaagc aaaatcaatt ttacataatt attttcgatt
    75901 cgttcgataa atgaagctgt ttgagttggc gtattctgcg cttcttctac taattggata
    75961 atcttagcaa agacagtttc ggaactcgtt tttgttactc gaatcgtgat gggatttcct
    76021 tgattcagcg ttcctgcata catctcatcg cctaaatatt tttctacagg cacagattca
    76081 ccgcttaatg cagactcatc gatcgttgcc tgtgtgcttt ctaaaaagcc atctatcgga
    76141 acagctgctc ctttagcgac aaataccaag ttatccacct ttagttgaga aacatctact
    76201 tcttgcattt gtccattttc ttttaataat tgggcttttt gtggttgaag attcatcaaa
    76261 gcagtaattt ctttttgact tttattagtt gtgtattcct ctaatgcacc gcttaaacaa
    76321 aagatgaatg tcaacattgc tccttcaaag taattaccga tcaaacaggc accaatagca
    76381 gctaaagcca tcaataaatc cacattcagt gtccgatcat tccacaattc tttcaagcct
    76441 tccgatgttt gtttatatcc accgatgata atggcactga tataaaaaag tggggtgatg
    76501 gtaagagaga atcggtcgaa gataaaaccg aagatcataa ataaaaggca gccgattgtt
    76561 gctgcaaaag cttttttctg attagtcatc gttattagac ctccttgtca aaacaaggat
    76621 agcataataa aaatgtaatt gataataata acagctaaat gagaacgata atggttatca
    76681 tttggtgatt aagcttgatg ttgtttttat tatttataat gattattatt aaagaaaata
    76741 aaaaaccaga acatttctca aataagagaa gtgttctggt tttttctaca ttgcaataaa
    76801 ccaataacca atcaaaatga taccaaggat aatacgatac cagccaaaag cggtaaagtc
    76861 gtttttcttc aaatagctta gtaagaattt gatagctaag acggaaacca caaaagatac
    76921 gaatgttcct acaagaagaa caacagtttc ttccattttg aatgaattcc cttcagctaa
    76981 atatttgacg atcttcaagc cgcttgcgcc aaacatgaca ggaatcccta agaaaaatga
    77041 aaactctgta gcgacaaaac gcgaagcacc aatcaagata gatcctagga tcgttgcgcc
    77101 agaacgggat gttccgggaa caagtgccaa gacttggaat aacccaacaa gaagagctgc
    77161 ttggtacgta aagtcattca gagaagtcca acgaggtgtt ttgtttttgt tgcgtttttc
    77221 gacaataata aaggcaatac cgtaaacgat caaaacaatg gcaactggta agaacttgtg
    77281 gaaatttgct tctaaccaat catccaaagg caaaccaatg atgatggctg gtatgcaagc
    77341 aacgatcact ttaaaccaaa gtgtccacgt atcttttttt tctaccgttg atttacttgg
    77401 agaaaatggg tttaacttgt gaaaataaag aacgacgaca gccaagatcg cccctaattg
    77461 gataacgaca ttgaacatcg acataaattg tgaactggca tccagtttga tgaattcatc
    77521 tgctaggatc aaatgaccag tactactgat gggcagccat tccgttattc cttcaataat
    77581 accgagaatc actgctttga taatatttgc aaaaaacata aattccttcc ttcccaatta
    77641 agatacatct tatagtatac cgttattttt tgagaaaccc aatctgtttt ttaatattaa
    77701 gaaaaacttg agaaataaag cagataagta cacgaagaga aaaaagaaga caaagccctc
    77761 gttcagactt tgccttttat gattctctgg taaaaattaa aatatcccca ttatagaaac
    77821 gagtcgcgac tatgtgtttt cccgttatcg atataagacg tatcattgat gccgtggata
    77881 gaaaatcgac cgtttgcata agtgaccttt gttacgctgc catttaaaag cccagcacga
    77941 acaggctgtt taggatcgat cagattaagc aaaaaggcga tcgtcaaacc atgagatacg
    78001 actaaaacat ttccaccacc atttttttcg cagtgatggg cgatatcttc aaatcctgtc
    78061 catacacggt ctcgcaatgt ttcataagtt tccgcccacc cagcggtatc taagttgtat
    78121 acagcattag caatttgttc aaaagaaact tctgtggtaa acatttcatc atatgtttta
    78181 aaattcaata cacgagggat cacaccccac atttccatgt catatccacc ttcaagagac
    78241 ccgaaacacc attctctaat ccttttttca ataaaataag gaatttcttt tcccttagaa
    78301 tgttctccta gaataatacg ggcagtttcg attgcacgac cactgtcact agaataagca
    78361 aatgaaaagt cgacattttt taacccgcga cctaaataat gaatgccttc ttgtccttgc
    78421 tttgtgaggg gtgtatcaca ccagccttgt actcgttcaa ttgtattgaa catcgttttt
    78481 ccgtgtcgta cgatataaag tgtagtttct gtcattttat tctcctccta agtcgtttta
    78541 acgattgaaa aaaggatttg tccttttttc ctgttcaatc gtcgttgcat cgccatgtcc
    78601 tggatagact gcaaattcat caggtaatac aaacagctgg gtccgaatac tatgaagtaa
    78661 ttgttctaaa ttccctgtat acagatcggt tctaccgata cttcctctaa acagggcgtc
    78721 gccagaaacg acaaaatcat caaaaataaa gctgacgctt cctatagaat gccctggggt
    78781 agggacgacg cgaaaagaca tgtttcctaa agtataagtt ttcatttcaa attcatattc
    78841 tgcaggcgag acaataacat cagcaatatc atcatgtcta ccgagtccag aaagattcaa
    78901 aatcggatca cctagccatt tttgctctag tgggctgaca taaactggga tttgataata
    78961 cgcgcgtaaa ggttccactg caccgatatg atcgtagtga gtatgggtaa gcaaaatcgc
    79021 taccggctgt tggtttgttt ttttgatttc ttgtttgatt cgttccgcat cttctccagg
    79081 gtcaatgatc aaaagtgctt cttcgttgta gaccaaataa cagttttctt caatcattcc
    79141 tgtttttaat ctttcgatat gcatgtgcat tcctccttga tagccaaaac ttctttcatc
    79201 cattagtata acgcattcat tgctaggaaa caaaaacagg tacttatttc tctttactta
    79261 tctgaattat cagactatat gaaaagtatt tggatattct aaagagaagg aaagtaagtt
    79321 ttcatagcat tttaatatgt ccttgttaca ttagattcat ccaaaaatcc aaattctata
    79381 tcctatatcc ctgcctaatc agcagggtgt ttttttatgt ttggaaagag agctcttttt
    79441 gctaaactag gttttttcag gtaatcttag agagaaagag gtggtggaaa tgatcaaaca
    79501 gtcaaaaata tctgtgcggc acttagtaga atttattttg cgacgtggaa gtatcgacaa
    79561 tcgtaaaaaa agtaaccata ctgcattaga aggagcgaga atccaccgca agctccaaaa
    79621 agatgcggga gaaaactatg aaaaagaagt ctttttaaaa acaacagttc aattagatga
    79681 atattacctg atcgttgaag gccgtgcaga cggtattttc aaaagagacg gtatttatta
    79741 tatagatgaa atcaaaacct ccgaaccacg atttgaagat ttagaaccag aacaagtgga
    79801 acttttcttt catcaagcaa gggtgtatgc ctatatctat agtcaagaac atgatttaca
    79861 agaaataaat ctgcaattga cttacttcca gacggcagaa gaagtgatca cgagaaaggt
    79921 tgaacatcag acaagagagc agttagaaac tttttttaaa aagctgactg aagattataa
    79981 agaatggctt gtttttcaag aaaactggcg cactgtacgc aatgcctctt tgatggcttt
    80041 gaaattcccc catgatgagt ataggaaagg tcagcgtgaa ctagcggtag ctgcttataa
    80101 aacgatccgt acgaaacaga aattgtttgt agaagcacct accggaacag gaaaaacaat
    80161 ctctacgtta ttccccgctt tgaaagctgt aggggaagaa gagggagaaa agatctttta
    80221 tctaacggct aaaacaataa ctagacaagt agctgaagat gctatgacag cattaaaaga
    80281 tacaggagct gaagtaaaaa gtgtcacttt gacggcgaaa gacaagatct gctttttaga
    80341 tgagacgacc tgtaatccag atcagtgccc atatgccaat ggttattaca atcggattaa
    80401 tgaaggttta tgggatcttt tgaatcatga gaatcagatc actcgtgaag tcatcgaaac
    80461 ttatgcaaga aagcatacac tttgtccttt cgaactatca ttagatgtca gtatctggtg
    80521 tgacgtaatc attggggatt acaattattt atttgatcca actgtttatt taagacgttt
    80581 ttttgaagat gaaaaaaacg aggactatct gtttttgatt gacgaagcac ataatttggt
    80641 gaatcgttcc cgagagatgt attcggcaga actatcttat gaaaaaacga aacgaagtaa
    80701 ggaagctata ccaaaggaat tcaaaaaact tcatcgccgt ttcaacaaac tattaaaaga
    80761 atttgattcg atccgagaaa tagcaaaaga agatcattgg gattatcatc atcaaaaagc
    80821 accggctgaa tctttagtaa aggcaggtta tcaattaagc gaaaaaatta aagaatggct
    80881 ggcagaattt cctgagcacc catcacaaga acaattgctt ccttattatt ttgatttgct
    80941 tcattttttg aaggtcagtg aattttatga tgatcactac gaaacaacag tcgaaaaaac
    81001 gtatcgcgat ctgatagtaa aagagttttg tattgatcca agcttgtttc ttgagcagtc
    81061 gttggataaa ggaaaaagca gtattctttt ttctgctagt ttttcaccac tctcttatta
    81121 tcaggaaaca ctggggggac aaaaaagtct ggcttacaaa ctgccgagtc ctttcccaga
    81181 aggaaaccag caagttttca tcgcaaatta cctagagacg acttatcgaa aaagggaaca
    81241 cagtctggca aaattagtag agacgattca tgcttttgct gatggaaagg tcgggaatta
    81301 tttcgttttc tttccttctt atcaatattt agatcttgcg gtggaagcat tcagacagca
    81361 atatcccgac agcaatgtgc taatccaaga aacggacatg aatgaggaag aacgcgaacg
    81421 atttttaaca aaatttcaaa caaatcccgc tgaaacattg attggatttt gcgtacttgg
    81481 cgggattttt tcagaaggaa tcgatttgag aggggaccga ttgatcggca gtatgatcgt
    81541 aggtgtaggt ttgccgcaga tgaatcatga gcaggaactg atcaaatcat attatgatga
    81601 gaaggaacac cttggatttg cttacgctta tcagcttcct ggaatgaaca aagtcttgca
    81661 agctggtggt cgagtgattc gtggcatggc ggatcaagga atcgttgtat tggcagatca
    81721 acgattttct agtttttctt atcgacgttt attcccacaa cattggcaaa cagcaagaga
    81781 agtacgaagt gttggggaat tggaagaagg aatacagcgt ttttggttat caaaagaagc
    81841 agtaaatcaa aaaaacgagg aatgacagac gtcagcctcg ttttttgatt aacgatagtt
    81901 agtgaattgc aactcgattg gtaagtcaag tttacgtaat aaagcaatca cagcttgtag
    81961 atcatcacgg ttcttacctg tcactctaat ctgatcttct tggatttgtg cttttacttt
    82021 cagtttttca tttttgatag ctgtagtgat tttcttcgcg ttttcacgat cgattccgtt
    82081 gaccaaatcg gcagtttgtc gagctttgcc acctagagcg tgttctgatt cggaaaaatg
    82141 gatatttttg attggcacat ttcttttgat cagcttacca aataatacat ctttgatctg
    82201 ttcgattttg aaatcatcat cgctcaatac aactagattg ctgttctcta atttgatttc
    82261 tactgtagaa tccttgaagt caaagcgatt ggacaattct tttgttgttt gctgaatcgc
    82321 attttttact tcttctgtat tgacttctga tacaatgtcg aagctagcat cttttgccat
    82381 aggaaccctc ctgatataca tataaatatt taccatacat ctatcttatc ataggattag
    82441 ggcagattct tacctgtttg ctaaaattct tctcatttga gttcgaagta ttttatttta
    82501 atagataaac tgttattctt acatttggaa taccaaagta ggggagaggt gcttgtgagt
    82561 aaaattatga ctgcgtatca taaaaatgaa agattaaaga aaatagtggt tattttgata
    82621 accggattga ccgctgcggt cgctttaaat tattttttga ttccagccaa tgtcttttct
    82681 gcagggatga atgggatcgc tcaaatcatt tcctcgcttt tatatgaatg gtttcatatc
    82741 aagatagaca caggaacatt tatttttctt ttgaatatcc ctgtgtttgt attagggttt
    82801 ctcaaagtag gaaaacgagc aacgatcctt agttttgtga atgttgtatg tgtatcggtg
    82861 atgacgatgc tgcttccagt cggacagatc actgataata ttttgatgaa tgccctagta
    82921 ggcggtgttt tattaggtct tggcgtagga ttatctttaa aaatgggctt tacaactggt
    82981 gggatggata tcatctctct tgtactttca caaacaactg gaaaaacagt cggaaactac
    83041 atgctgattc taaatggtat cattgtagtc atcgcaggct tcttctttaa ctgggaaagt
    83101 gccttgtata cgattatttc catttatgca atgactcaag taattgatgc catccacacg
    83161 agtcatcaaa aagtaacagc aatgatcgtt accgtcaagc cagaagaggt aacagaagaa
    83221 ctagcaaaac ggatggtacg tggaatgaca ttactgccgt ctgtcggtgg ctattcaaaa
    83281 aaacaaggga acatgatcat gatggtcatc acccgctacg aaatgtatga tcttgatcag
    83341 atcgttcatg aaatcgacga cgatgcattt atcaatattt taccaactca ttcagtattt
    83401 ggccggtttg caaatgaaaa cgaacaaaaa atgtatcgaa caactggcgt attgccagaa
    83461 ataaaaaatc gttcacaaaa aaaatgagga atcaggttta ttttagaata aatttaatct
    83521 attacatcta ataagaacat ttttataaat ttaaacgaga atcttacttc taaattctca
    83581 tttacaagca gctaaaaaaa gagtatgata aataaaaatc gtgttaagga gtgtcgtacg
    83641 atgagcgaag caaaccaaga acggtctgga caagaaatag aactaatcaa agaacgtatt
    83701 cttgctgcct tggaaatggt gattgatcct gaattaggaa tcgacatcgt caatttaggc
    83761 ttgatttatg atatagaatt caatcctgaa aatggagaaa cagtcattaa gatgactcta
    83821 acaactatgg gctgtccatt agcagatatt ttaacagaat ctatccatga cgcattaaaa
    83881 gaagtgccag aagtaacgaa agcagaagtc aaactagtct ggtatccagc atggacgaca
    83941 gataagatga gccgttatgc acggattgcg ttggggatac gatagaaatc ttggctgact
    84001 agctatgaga agcaaatagg aaaaacaaaa aagcctttta tcctttctag aagaaaagag
    84061 ataaaaggtt tctttgttta taaaattttg tctgctatat tataagttaa ttaaataaat
    84121 gtgttctatt gataaaggac attcaaatcc ctttcctttt ggaatccttc ttttttacat
    84181 cagtttgatt ttcgtatagt attctttctc atcttcacga taaatcgcag ccccattttt
    84241 ttgttgtgct ttaagactgc caagattttt tttatttaca gacaaaagtg cctcatcaat
    84301 gccgattttt tttgcctctt gtagtactaa tgctaatcct tgtgtggcat atcctttttt
    84361 acgataatta ggggagatgc cgtaaccaat atggccagcg ccgtttctta atgtttcgtt
    84421 cagtttatgg cgcaaattaa aaattcctac atactcatgt tcatcacttt ctaaaataaa
    84481 gacggttgcg ggaacgtaac tctcaggaag atcgattcct aaagacgttt tttcgcattt
    84541 ttttacataa tctaaaaatt cagcaaatgt atagccataa gcattgttga taaatccact
    84601 ctcatttggt ccaaagctag tttgtagctg ataagctttc tttaaatctg cttcccatag
    84661 tttgatcagt ttcatcgtat tcacctcttt aagtaacctt attcatttgt tttctactat
    84721 agcactattg ttgtaaatag ccatgcctat ttttatttat tgtgtcatat cgtattaaga
    84781 atcatcgaac aatacaaata tgaattacaa taaaaaaatt atttgaagtt cgttcattcg
    84841 ttacttatga tctctagaag aaagaaaacg tgaattactt cagcgtctag aattccagaa
    84901 ggatagtaat caacagaaga aataatcaat atccaaatga aagaagatag ctgaatcgag
    84961 aaaaagagga aaaaagaaat gaagaaaaaa ataaaatagt tactaatccc agagtcgttc
    85021 gtttaacatt gaaatcgatc atatggataa aacagatttt ttcaccaacc ctcaatagat
    85081 gatggagttg ctcggatgaa ttatttgtgt agatggcata agggagggcg tacagaaatg
    85141 aaaaagaaca aaaatatgtt cttgacaaaa aacacatgta atcctaaact aaaagatgtg
    85201 atgcggctat ggcggaattg gcagacgcgc tagcttcagg cgctagtgag ggtgacctcg
    85261 tggaagttcg agtcttctta gccgcataat ttgttttttt ataaagagaa ggtacacctg
    85321 gagcgatgag aaagaaaata acatattatc taaaagaata taggaaaaat tttaaacaac
    85381 ggaaccagat tcaaataaat caaaaaaaat ttgtgtgaag gtgggacagt ttaaaaccta
    85441 atagattgat tcaaatagta gatttataga ttctgataca agaaatactg gcaaacgata
    85501 gttaaggaat aaagactaaa cttaaactca aaaagaggtc atgcgaaaga ataaatcgca
    85561 tgacctctta ctatattttg aatgtgttta aacgttcaaa taatgaatct tagtaccaac
    85621 cgtttgcttc ccagaatgct ttcgccgctt cccaagaacc ataacgtgaa gtaacatatt
    85681 gttctgctac tctttcttgg tttgcagcag agtagtcacc atttaagtaa gaagaatcta
    85741 attggtaacg gccgatgtaa cgtccgttcg ttgctgtgta agaaccgctt gattcttttt
    85801 gtgcgatcca ttcttttgca gagcttgtac ttgctggagt agcagcagtt tctgttacag
    85861 caggagcagg ttgtgtttca gcaacaggcg ctgcttgtgt ttccgtttga accgtttctt
    85921 gtacaacagg ttgttcagct tgaacaggtt cagcttggac tggtgcttct tgaacggctg
    85981 cttgaggttc agcagctgct tgtgcagagc cttctgttgg gattgttaat tgttgtcctg
    86041 agtagatcag gttaatatca gaaattgaat ttgattctgc aatggcattg atcaaggagt
    86101 tatcaccaac gtatttttga gaaatcgttg atagagtatc acctgattga acggtataag
    86161 cttcgtccgc atgagcagtc gttcccatga agaatgcagc gccggcagcc aaagttgttc
    86221 caaaaagtaa agttttaagt gatgtcatga aaaatctcct ttattcgtta aaaagtttta
    86281 tttgttgtgt tcaacgagga atactttaac acgtgaaaat atttcatagg taaaagaagc
    86341 atgacaattt atgacaaatc cacgtttttt gtaacagaat gatgttcgct cgatgtgaaa
    86401 aatgatgagg aatttcacat aatgcagaaa taatgggatt agaacaggtg ttctgatgag
    86461 aaaagaaatg tataaataac ttgaaagaaa ttgcttttgt tcatcatttt atttacatat
    86521 tgcgtatatt ttttgtattt ttgcttgaga tgttacaata aaagaaaaag gaggcggttc
    86581 caatgagtaa aagataccag aacatcatgg tagcagttga cggatcaaga caatcgatca
    86641 aagcgttcgc tgaagccctt gacttagcaa aggacaatga agcccactta tttatcgtgt
    86701 caatcatcaa caaagttgag ctgacccata gtgcctatgc cttttcaaaa atctatgcag
    86761 atgaaaaaca aagaacagaa gtagccatgc tgaaaaaaat caatgatgcc aaagagtacg
    86821 gcattgctga gatccacgca atagttgaaa ctggagatcc aagaaatttg attgccaatg
    86881 tcatccctgg acaagaaaat attgatttga tcgttatggg agcgacagga aaaggtgcta
    86941 tacaacaagc attagttgga tcgaccgctt cttatgtcgt atcacatgcc ccttgcagtg
    87001 tgttggtcgt gaagtaatga gataagggag gaatagaaaa tggttcgtcc tcaagaagtc
    87061 cgtgcgccaa aagaaaaaat agaaatttta gcaattattg aagacggcac acaaacaaag
    87121 aagggatact cgatcgcttt agtaaagtgg aaaggaaaaa aaggtgttgc tctgagatgg
    87181 gatggagata accaacaaga taaaggattc cctgtcacag ctaacggtta tcatccagcg
    87241 tggtttgttc tgcctgataa atttatggaa ttatacagct atgattatgc aagagccgca
    87301 gcatcaatca aagcattaga taaattaaca gaagagcaga atgaaatgga ggaaaaataa
    87361 aaaagacgaa ccaatcagcc tttagaaaac tgattagttc gaggagtaaa aatgaaaaaa
    87421 ggttatttgg gatgaaacta gaataatgcg tataacttaa ataaaactta aagcaataaa
    87481 atggcaagag ggtgaggcaa atggaagcag gaaaagtatt acaggaagta aaagcactat
    87541 gtgcagataa aaaatatgaa gaagcgaaaa gcctgatcga aaagaacaaa gaaaatttgg
    87601 aagaaaagta cccgatcgca caagaattta tagaattaaa acaaggaacg atccttcacc
    87661 gattcaaaca tttttttggt ataacagaat agaaaaaacg attaaagatc ggcagaaatt
    87721 tgctgcatct ttaatcgttt tctttttaaa catgcgaggg attcaattct gattcttata
    87781 taaaaaatag atccaaataa taagaaaaat tactgaaagc gtcaattcga tgatgtgtgt
    87841 tattaataca gacgttgttt cccaatgcct aaaagaaaaa atttgataag taaaatatac
    87901 agcaggtaaa gaggccagta aaactgaaaa cttctttttt gtccatttta tgtaatagaa
    87961 aagaatgctt atcataataa aaaaaggaat ataaaaaaca aattgaccga tcgcgatcat
    88021 actattgcct ccgataaata aagtccatga tacaaaataa cactttgtgc gaaatggcgc
    88081 aagcagtttt gtggatttat ccggtaaaat ctgtatcgat tttgaaatta gaggagaaac
    88141 ttgctataat caaagtgaaa gaaggagtgg gattttcatg gatcatgtag tgttagaaat
    88201 cgatttgcat ttgatcaata atattcgggt gatttactat gttgtaagta acagtgtcga
    88261 acaacgtgta ctgacgaata aaataaatgg tattttagca aagaaagacg ttcaccgatt
    88321 caataatggt gaaggaagtt attatagtat cccagtagaa aaaattattt atacgacagt
    88381 caaagtcaga gaagatctag ataccaaaaa agcatatgaa cctattttta caacttattg
    88441 attgacagca gatggaggaa aaaaatgaat ccatatgaac aacttattca agatttgatc
    88501 gatggaaaaa tcgaaaagat tgatgtaaaa agagaagaat taatggcttt tcgagaagcg
    88561 tggctgaagt tggagaatcg taaatatgtg gtgggaaaag cctcactgaa cggcaatgtg
    88621 acttatcatt acgatccgac acgtttattt tagtatgaag tattcagaaa agaaccaaag
    88681 gaggacgatg cagcagcatt gtcctccttt gattttacaa aagtgaaagt tttacttatt
    88741 tgaatagatt tttaaatttg tttttgacac tgtcgatatt tacatctttt aaaagatttt
    88801 gggctttctc tttataaggt cctaattgtt ctttatgttc ttcgataaat cgttttgcgc
    88861 catcgaaatt gccgttctta atcatttcct tgactttttg aaataattct tcttgattca
    88921 ttttgaacac atcctttgct atcaacatga ttttttacat ggacaaaacg agaaaaactg
    88981 atttatccac acgtcaataa tatcaaataa cgatcatttt tactaaaaaa acactcgatt
    89041 ctcgcttcta aagtaggaga aaaatctcca acttgggacg gatggaattt ctttaactga
    89101 cccatatact gaatatataa caaggaggta gaaagatgaa agtgattaaa tatttgattg
    89161 gactggcggc gattagtggt attttgctat ttggactgaa atattatact gaaggaagtt
    89221 atggagaaat ccctggtata cttgatcagc taaatccatt agttgaaaaa ggagaggtct
    89281 atgtaaagac acaaaaacca gaggaagtaa atgaatatgg tacagcaagg tatgtgcaga
    89341 aagctgctga tgccaatggg aaagaacgaa cggttgaatt taatggtctt tctgtgttaa
    89401 aagaaaatca ttatttgaaa attagcaata aaggagcaca catagaaacg tatgaggaag
    89461 ttcctagaga aaaagttccg gagaaagcat tagcaattat tgggtaaatc agtttttgta
    89521 ttaagaatac gcccgatttt attattcata atttaattat gtaaactaaa tacaagtagt
    89581 aaaaataata caataatccc cctgcaaaaa gattgttctt ttacaggggg ttcatttttt
    89641 cagcaagcac atcaaattgg gatggcaggg ttcgaaccta caattgcttg attcagagtc
    89701 aagtgcctta ccagtttggc tacatcccat ttattcaaca aaataatcat agcactttcc
    89761 taaaaaaacg caagttattt ttcttgatcg gatagttgtt gctttactcg taaaaggcgg
    89821 cgtactagtt tcttttctaa tccagcagga agggcaatca gttctgctac tgacaagacg
    89881 gtgtccaata actgatattc tttgacaggt tcattcataa tatgatagat gtttgctaaa
    89941 cgttcaatat attcaaagcg agtatactct gttcgagcaa ttagaaattt caataaatcg
    90001 gtggctttct cgtactcttg atctgcgtaa taaacaagag attgacgata caatttgatt
    90061 tccagttcat tgagggtagc aggtctgcga cgctcgttcc actcattaat agagacttta
    90121 ccttgaacat ttcccttgca gtcacggaca aaaataatcg gaatttcatt tggatccatt
    90181 tttttatgtg tgaatttttc cattatctac gctcccttca aaggtttggt atcttgagta
    90241 taagggattt ttgtttgaat tactagcttt tctccaaagt tagcatctgt ccacccattg
    90301 cagtgaaaat cgccgaaaaa tcgttgatcg gtactgctcg attttttaca ccatagggat
    90361 cgttgacata aatattttct ttgtcatatc cagtgactac acaagcatga acaagaggag
    90421 tgactcttac ttctccatta tttgtggtcc aagtcataaa atcagtttca tctgggactt
    90481 caaaattgat agtcacagaa gtccagacag gatttccttt agatagtgct tttttgatat
    90541 catcgagttg agcatcggtt tttggaaaag tgtgataatc cgtttggacg atttgctgag
    90601 caagggaggc aactggggga acatagacga ccatagccca gtctccgcca ctgatatcac
    90661 caacaaatcc ttcattagga tcgccatgag tcccatctgc attgaaaaca gggacgtaat
    90721 ccaattgctc agctaactgg tttttagttg tttcataacc ataaaaagat aaaagcatag
    90781 aaagcgaagt gacttcacag ccattttcta aagaaggaga atcaaactgg ctctctaatg
    90841 gaacatctag taaaacttct gctttctctt ttgtcttttt cgttttttgt gttgaacttt
    90901 tttgtgcagt gttcattgta tgttctggag aatggatatg taggtaataa cttgtaccgc
    90961 ttaataaaag agcagctgtg ccccctagaa acaatagttt tttgaacgtt tttttcttca
    91021 tttgaaatct cccttttcag ctgtttatct ttcctattat aaatgtattt ttattggaaa
    91081 tggaagtatt atattttaat atgtaggaaa taattagttt ttaaggaata tgttttaatt
    91141 ttttgaaaaa aattcttcta aatacaacag ctgttttaat tgtgaaaacg aaaacagtac
    91201 gctataatgc ctgtaaggtt gatttttaac tgtaaataaa aatcaatgag ttaaatctcc
    91261 aaagaaatag cagtggtaat gtggagaaaa gttccagcag tttaggagga ttttgatgac
    91321 ggaagaaatg attaatttag gagaacaata tgcatgcaaa ccaattggtt ttacaaaaac
    91381 ggtcattggt gaagttgtat caaaaatgac aaactgcgcc gtggtcaaag ttgcccaatg
    91441 tgctgcagag gaccaagaat tattagatga aaaagcaagc atggttgttg caaaatatga
    91501 tacatttgaa taaagaaaac aattggacgt gcggcgtgct gcaagtccaa tttctttgag
    91561 aaggtaaatc agtattcttt tcctattttc tggagaagaa aaagcgaggc gagttgtcat
    91621 ggtaacattc tttacggttc tattgttttt attcgttgtt gtgatgtttt tatttctttg
    91681 gctggttcga aaagaaatta tttatcggac tgtgcgaaat cgatgggtct acttggtgat
    91741 acccttctta gtgtcactag tcatttggta tacactcatc agtcatccta cagcagatga
    91801 attggcaaaa gggatcttgt cagcaatgat ttttattagt tttttgttgg acagtagagg
    91861 aatcacagaa gaaggacttg ttttgaatag ctttgacaaa aaaggtgttc ctttttctga
    91921 gatcaataaa attgtattat atcagccaaa aggttctaaa atcgtaaaaa tgaatttttt
    91981 ccgaaacgga tggcgaggac cgatgctgaa attttctgca tcattagaag aattagttcc
    92041 atttttgtcc caacgcttaa acgatgaggc agagattgat attatgattg atccagaata
    92101 aaaacagagg ttgcgacaag atgtttgtca caacctctgt tttttatttc aaataaaatt
    92161 atccaaatac gcggaagcga tcggcatcgt tcatgtattc tttttcccca gccggtgttt
    92221 ctggtgaacc gaatactaat tgcgaacgta gtttccagtt tgaagggata ttccattctt
    92281 ttgcaactgc ttcgtcaata actgggttgt aatgttgcaa gtttgcgccc aatcctttat
    92341 caactaatgc tacccaagta ttagctgttg cgattccgtt tgattgttct gaccaatctg
    92401 ggaagttgtc tgcatataat tcaaattgtt cttgtagacc ttttaccacg tcagtatctt
    92461 tgaagaataa tactgtacca taaccatttt tgaaaccagc taatttgttt tgtgtatttg
    92521 ggaaagcttc tgctggagtc aatgggcgaa gtgcttcttc agtgatttcc caaagttttt
    92581 catgtgcatc tccgaaaagg ataactgcgc gtgttgattg agcattgaaa gcagttgggc
    92641 tttctttaat tgcttctttg atcaaagttg ttaattcttc attagaaagt gaaacattac
    92701 gtcctagatg atagattgaa cggcggtttt tcaaagtgtc agtaaaagtt gtcataataa
    92761 aatttctcct ttgatttgcg ttttgcattt ttttaattga ttacgaaatg aaatatagca
    92821 ccttacaaaa agtaagtaaa cagatatgct cacaaaaaat aagcgaagtt caaaaaacaa
    92881 ttttaataag aaaaatcgtt atgtaaggat tttcttagtt atcgctttca ttgttgtgtt
    92941 ttaggaattt ttgcttattt gaaaaaaaca gctgatatat aattattaaa tctctatctt
    93001 ctttttttta tgatattgcc attaaaaatt acttgctttt atagaaaatt agtttatatt
    93061 tcttaaataa gttttttagt taaatttttc ggtaaagatg tataatattt tctgaaaatt
    93121 taaagaattg gggtatagat tatggaaaaa cagcaagaca agggcttctt cgggcagccg
    93181 aagggattgt caactttgtt cttcactgag atgtgggaac gatttagtta ttacggtatg
    93241 cgtgcattac ttatctatta tatgtacgat acagttgcca acgggggact tggattacca
    93301 cgagcaacag cattagctat catgtcgatc tacggatctt tgatctacat gtctagtatc
    93361 gtcggcggat gggtatctga ccgagtgtta ggagcaaaac gcactgtatt cttcggtgga
    93421 gttttcatta tgcttggcca catcgtcttg gctttaccat ttggtgtaag tacattgttt
    93481 gtttcgatgg cattgattat tatcggaacc gcctttttga aaccaaatgt ttctggcatg
    93541 gtcggacatc tttattcaaa gactgacttg cgaagagatg caggattttc gattttttac
    93601 atgggtgtca acttaggggc attattagca ccactaatcg ttggtacaat cggtcaagaa
    93661 tataactatc atttagggtt ctctttagct gctattggga tgttctttgg attattacaa
    93721 tacatcatcc aaggacgcaa gacattagac ggagtgggta caacaccgcc gaatcctttg
    93781 acaactgaag aacgtaaagg attcatccgt aacttgatca tcgcacttgt tgttatcgct
    93841 gcagtattcg gcggggcaca actaactggt catctgacaa ttgacttttt tgtcaataca
    93901 atcagtgtat tggggattat cttaccgttg tattacttta tcaaaatgct gacttcaaaa
    93961 gatgtaactg ctgaagaaaa accaagagta tgggcttata tcccattatt ccttgcagca
    94021 atcattttct ggtcattaca agaacaaggt tcatctatct tagctttatt tgctagtgaa
    94081 cgtacacaat ctacgctatt tggtgtaacg atccaagcaa gctggtatca atcattgaat
    94141 ccaattttca tctttattct gacaccagta ttcgtaacga tgtggacgaa acttggtgaa
    94201 cgtcaaccat ctacagtagt gaaattctct cttggacttt tatttgcagg attatcgtac
    94261 ttgctattga tgttgccggg tatgctttat ggtacaagtg gaaaagtaag tccattgtgg
    94321 ttgttgggaa gtttcttcat cgtggttatt gctgaattgt gtctttcacc agttggtttg
    94381 tctgtgacaa caaaattagc accacgagca tttgaatcac aaacaatcgc tatttggttc
    94441 ttagctgatg cttcttcaca agcaatcaat gcacaaattg cacgcttcta cacaccggga
    94501 acagaatctg cttacttcgg tattatcggt gcagtagcaa tcgtcggtgg tatcttgcta
    94561 tttactgtga aagaaccaat caaaaaacta atgggctcta ttcattaatc aatgaacata
    94621 aaaacaggaa ttgcttattt gcagcagttc ctgtttt
//
LOCUS       DAFEEZ010000003        85548 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000003
VERSION     DAFEEZ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 85548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.003"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..171
                     /locus_tag="LP245_000194"
     CDS             <1..171
                     /locus_tag="LP245_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBL1518141.1"
                     /translation="SLFPLYHGSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFK
                     IEYTKKRQRLAY"
     gene            406..642
                     /locus_tag="LP245_000195"
     CDS             406..642
                     /locus_tag="LP245_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518142.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            649..2601
                     /locus_tag="LP245_000196"
     CDS             649..2601
                     /locus_tag="LP245_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBL1518143.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="LP245_000197"
     CDS             complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="LP245_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBL1518144.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3532..4572
                     /locus_tag="LP245_000198"
     CDS             3532..4572
                     /locus_tag="LP245_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBL1518145.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            4670..4858
                     /locus_tag="LP245_000199"
     CDS             4670..4858
                     /locus_tag="LP245_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBL1518146.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(4916..5269)
                     /locus_tag="LP245_000200"
     CDS             complement(4916..5269)
                     /locus_tag="LP245_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1518147.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            5800..6222
                     /locus_tag="LP245_000201"
     CDS             5800..6222
                     /locus_tag="LP245_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL1518148.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            6219..6449
                     /locus_tag="LP245_000202"
     CDS             6219..6449
                     /locus_tag="LP245_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1518149.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            6947..7147
                     /locus_tag="LP245_000203"
     CDS             6947..7147
                     /locus_tag="LP245_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBL1518150.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            7174..8367
                     /locus_tag="LP245_000204"
     CDS             7174..8367
                     /locus_tag="LP245_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1518151.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(8435..10000)
                     /gene="guaA"
                     /locus_tag="LP245_000205"
     CDS             complement(8435..10000)
                     /gene="guaA"
                     /locus_tag="LP245_000205"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBL1518152.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(10059..10982)
                     /locus_tag="LP245_000206"
     CDS             complement(10059..10982)
                     /locus_tag="LP245_000206"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBL1518153.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            11178..11783
                     /locus_tag="LP245_000207"
     CDS             11178..11783
                     /locus_tag="LP245_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1518154.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12091..13107
                     /locus_tag="LP245_000208"
     CDS             12091..13107
                     /locus_tag="LP245_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL1518155.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13248..14549
                     /locus_tag="LP245_000209"
     CDS             13248..14549
                     /locus_tag="LP245_000209"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBL1518156.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14595..15257
                     /gene="deoC"
                     /locus_tag="LP245_000210"
     CDS             14595..15257
                     /gene="deoC"
                     /locus_tag="LP245_000210"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBL1518157.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            15278..15676
                     /locus_tag="LP245_000211"
     CDS             15278..15676
                     /locus_tag="LP245_000211"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBL1518158.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15742..16824
                     /locus_tag="LP245_000212"
     CDS             15742..16824
                     /locus_tag="LP245_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1518159.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            17036..18598
                     /locus_tag="LP245_000213"
     CDS             17036..18598
                     /locus_tag="LP245_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518160.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18591..19724
                     /locus_tag="LP245_000214"
     CDS             18591..19724
                     /locus_tag="LP245_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518161.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19724..20680
                     /locus_tag="LP245_000215"
     CDS             19724..20680
                     /locus_tag="LP245_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518162.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            20779..21945
                     /gene="deoB"
                     /locus_tag="LP245_000216"
     CDS             20779..21945
                     /gene="deoB"
                     /locus_tag="LP245_000216"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBL1518163.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            21969..22787
                     /locus_tag="LP245_000217"
     CDS             21969..22787
                     /locus_tag="LP245_000217"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL1518164.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            22804..23511
                     /gene="deoD"
                     /locus_tag="LP245_000218"
     CDS             22804..23511
                     /gene="deoD"
                     /locus_tag="LP245_000218"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL1518165.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(23809..24495)
                     /gene="gpmA"
                     /locus_tag="LP245_000219"
     CDS             complement(23809..24495)
                     /gene="gpmA"
                     /locus_tag="LP245_000219"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBL1518166.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(24667..25248)
                     /locus_tag="LP245_000220"
     CDS             complement(24667..25248)
                     /locus_tag="LP245_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1518167.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(25381..26064)
                     /gene="rpiA"
                     /locus_tag="LP245_000221"
     CDS             complement(25381..26064)
                     /gene="rpiA"
                     /locus_tag="LP245_000221"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBL1518168.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            26383..26796
                     /gene="rpsL"
                     /locus_tag="LP245_000222"
     CDS             26383..26796
                     /gene="rpsL"
                     /locus_tag="LP245_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBL1518169.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            26880..27350
                     /gene="rpsG"
                     /locus_tag="LP245_000223"
     CDS             26880..27350
                     /gene="rpsG"
                     /locus_tag="LP245_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBL1518170.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            27444..29531
                     /gene="fusA"
                     /locus_tag="LP245_000224"
     CDS             27444..29531
                     /gene="fusA"
                     /locus_tag="LP245_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBL1518171.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            29703..30890
                     /gene="tuf"
                     /locus_tag="LP245_000225"
     CDS             29703..30890
                     /gene="tuf"
                     /locus_tag="LP245_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL1518172.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            31297..31605
                     /gene="rpsJ"
                     /locus_tag="LP245_000226"
     CDS             31297..31605
                     /gene="rpsJ"
                     /locus_tag="LP245_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBL1518173.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            31636..32265
                     /gene="rplC"
                     /locus_tag="LP245_000227"
     CDS             31636..32265
                     /gene="rplC"
                     /locus_tag="LP245_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBL1518174.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            32293..32916
                     /gene="rplD"
                     /locus_tag="LP245_000228"
     CDS             32293..32916
                     /gene="rplD"
                     /locus_tag="LP245_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBL1518175.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            32916..33206
                     /gene="rplW"
                     /locus_tag="LP245_000229"
     CDS             32916..33206
                     /gene="rplW"
                     /locus_tag="LP245_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBL1518176.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            33245..34078
                     /gene="rplB"
                     /locus_tag="LP245_000230"
     CDS             33245..34078
                     /gene="rplB"
                     /locus_tag="LP245_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBL1518177.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            34121..34399
                     /gene="rpsS"
                     /locus_tag="LP245_000231"
     CDS             34121..34399
                     /gene="rpsS"
                     /locus_tag="LP245_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBL1518178.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            34422..34769
                     /gene="rplV"
                     /locus_tag="LP245_000232"
     CDS             34422..34769
                     /gene="rplV"
                     /locus_tag="LP245_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBL1518179.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            34783..35439
                     /gene="rpsC"
                     /locus_tag="LP245_000233"
     CDS             34783..35439
                     /gene="rpsC"
                     /locus_tag="LP245_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBL1518180.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            35442..35876
                     /gene="rplP"
                     /locus_tag="LP245_000234"
     CDS             35442..35876
                     /gene="rplP"
                     /locus_tag="LP245_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBL1518181.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            35866..36054
                     /gene="rpmC"
                     /locus_tag="LP245_000235"
     CDS             35866..36054
                     /gene="rpmC"
                     /locus_tag="LP245_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBL1518182.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            36079..36345
                     /gene="rpsQ"
                     /locus_tag="LP245_000236"
     CDS             36079..36345
                     /gene="rpsQ"
                     /locus_tag="LP245_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBL1518183.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            36403..36771
                     /gene="rplN"
                     /locus_tag="LP245_000237"
     CDS             36403..36771
                     /gene="rplN"
                     /locus_tag="LP245_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBL1518184.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            36808..37116
                     /gene="rplX"
                     /locus_tag="LP245_000238"
     CDS             36808..37116
                     /gene="rplX"
                     /locus_tag="LP245_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBL1518185.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            37144..37683
                     /gene="rplE"
                     /locus_tag="LP245_000239"
     CDS             37144..37683
                     /gene="rplE"
                     /locus_tag="LP245_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBL1518186.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            37702..37887
                     /locus_tag="LP245_000240"
     CDS             37702..37887
                     /locus_tag="LP245_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBL1518187.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            37923..38321
                     /gene="rpsH"
                     /locus_tag="LP245_000241"
     CDS             37923..38321
                     /gene="rpsH"
                     /locus_tag="LP245_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBL1518188.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            38353..38889
                     /gene="rplF"
                     /locus_tag="LP245_000242"
     CDS             38353..38889
                     /gene="rplF"
                     /locus_tag="LP245_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBL1518189.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            39050..39406
                     /gene="rplR"
                     /locus_tag="LP245_000243"
     CDS             39050..39406
                     /gene="rplR"
                     /locus_tag="LP245_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBL1518190.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            39427..39927
                     /gene="rpsE"
                     /locus_tag="LP245_000244"
     CDS             39427..39927
                     /gene="rpsE"
                     /locus_tag="LP245_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBL1518191.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            39942..40121
                     /gene="rpmD"
                     /locus_tag="LP245_000245"
     CDS             39942..40121
                     /gene="rpmD"
                     /locus_tag="LP245_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBL1518192.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            40165..40605
                     /gene="rplO"
                     /locus_tag="LP245_000246"
     CDS             40165..40605
                     /gene="rplO"
                     /locus_tag="LP245_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBL1518193.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            40605..41900
                     /gene="secY"
                     /locus_tag="LP245_000247"
     CDS             40605..41900
                     /gene="secY"
                     /locus_tag="LP245_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBL1518194.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            41962..42609
                     /locus_tag="LP245_000248"
     CDS             41962..42609
                     /locus_tag="LP245_000248"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBL1518195.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            42800..43018
                     /gene="infA"
                     /locus_tag="LP245_000249"
     CDS             42800..43018
                     /gene="infA"
                     /locus_tag="LP245_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBL1518196.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            43051..43167
                     /gene="rpmJ"
                     /locus_tag="LP245_000250"
     CDS             43051..43167
                     /gene="rpmJ"
                     /locus_tag="LP245_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBL1518197.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            43185..43550
                     /gene="rpsM"
                     /locus_tag="LP245_000251"
     CDS             43185..43550
                     /gene="rpsM"
                     /locus_tag="LP245_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBL1518198.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            43578..43967
                     /gene="rpsK"
                     /locus_tag="LP245_000252"
     CDS             43578..43967
                     /gene="rpsK"
                     /locus_tag="LP245_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBL1518199.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            44047..44985
                     /locus_tag="LP245_000253"
     CDS             44047..44985
                     /locus_tag="LP245_000253"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBL1518200.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            45013..45393
                     /gene="rplQ"
                     /locus_tag="LP245_000254"
     CDS             45013..45393
                     /gene="rplQ"
                     /locus_tag="LP245_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBL1518201.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            45665..46504
                     /locus_tag="LP245_000255"
     CDS             45665..46504
                     /locus_tag="LP245_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL1518202.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            46480..47349
                     /locus_tag="LP245_000256"
     CDS             46480..47349
                     /locus_tag="LP245_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL1518203.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            47339..48136
                     /locus_tag="LP245_000257"
     CDS             47339..48136
                     /locus_tag="LP245_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBL1518204.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            48339..49085
                     /gene="truA"
                     /locus_tag="LP245_000258"
     CDS             48339..49085
                     /gene="truA"
                     /locus_tag="LP245_000258"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBL1518205.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(49418..52087)
                     /locus_tag="LP245_000259"
     CDS             complement(49418..52087)
                     /locus_tag="LP245_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBL1518206.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(52325..52513)
                     /locus_tag="LP245_000260"
     CDS             complement(52325..52513)
                     /locus_tag="LP245_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBL1518207.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            52783..53145
                     /locus_tag="LP245_000261"
     CDS             52783..53145
                     /locus_tag="LP245_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL1518208.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            53197..54879
                     /locus_tag="LP245_000262"
     CDS             53197..54879
                     /locus_tag="LP245_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBL1518209.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            54996..57032
                     /gene="recG"
                     /locus_tag="LP245_000263"
     CDS             54996..57032
                     /gene="recG"
                     /locus_tag="LP245_000263"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBL1518210.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            57081..58082
                     /gene="plsX"
                     /locus_tag="LP245_000264"
     CDS             57081..58082
                     /gene="plsX"
                     /locus_tag="LP245_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBL1518211.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            58204..58446
                     /gene="acpP"
                     /locus_tag="LP245_000265"
     CDS             58204..58446
                     /gene="acpP"
                     /locus_tag="LP245_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBL1518212.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            58714..59718
                     /locus_tag="LP245_000266"
     CDS             58714..59718
                     /locus_tag="LP245_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518213.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            59719..60663
                     /locus_tag="LP245_000267"
     CDS             59719..60663
                     /locus_tag="LP245_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518214.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            60663..61625
                     /locus_tag="LP245_000268"
     CDS             60663..61625
                     /locus_tag="LP245_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518215.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            61652..62566
                     /locus_tag="LP245_000269"
     CDS             61652..62566
                     /locus_tag="LP245_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518216.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            62592..64373
                     /locus_tag="LP245_000270"
     CDS             62592..64373
                     /locus_tag="LP245_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1518217.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            64721..65407
                     /locus_tag="LP245_000271"
     CDS             64721..65407
                     /locus_tag="LP245_000271"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBL1518218.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            65427..69008
                     /gene="smc"
                     /locus_tag="LP245_000272"
     CDS             65427..69008
                     /gene="smc"
                     /locus_tag="LP245_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBL1518219.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            69017..69826
                     /locus_tag="LP245_000273"
     CDS             69017..69826
                     /locus_tag="LP245_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1518220.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            69837..70835
                     /gene="ftsY"
                     /locus_tag="LP245_000274"
     CDS             69837..70835
                     /gene="ftsY"
                     /locus_tag="LP245_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBL1518221.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            71022..73289
                     /gene="gshAB"
                     /locus_tag="LP245_000275"
     CDS             71022..73289
                     /gene="gshAB"
                     /locus_tag="LP245_000275"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBL1518222.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(73378..73830)
                     /locus_tag="LP245_000276"
     CDS             complement(73378..73830)
                     /locus_tag="LP245_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBL1518223.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            73980..74930
                     /locus_tag="LP245_000277"
     CDS             73980..74930
                     /locus_tag="LP245_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBL1518224.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            74923..75882
                     /locus_tag="LP245_000278"
     CDS             74923..75882
                     /locus_tag="LP245_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBL1518225.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            75879..76634
                     /locus_tag="LP245_000279"
     CDS             75879..76634
                     /locus_tag="LP245_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1518226.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            76657..77610
                     /locus_tag="LP245_000280"
     CDS             76657..77610
                     /locus_tag="LP245_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1518227.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(78254..78550)
                     /locus_tag="LP245_000281"
     CDS             complement(78254..78550)
                     /locus_tag="LP245_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBL1518228.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            78905..79261
                     /locus_tag="LP245_000282"
     CDS             78905..79261
                     /locus_tag="LP245_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL1518229.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            79271..80170
                     /locus_tag="LP245_000283"
     CDS             79271..80170
                     /locus_tag="LP245_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBL1518230.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            80687..81418
                     /locus_tag="LP245_000284"
     CDS             80687..81418
                     /locus_tag="LP245_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL1518231.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            81563..83590
                     /locus_tag="LP245_000285"
     CDS             81563..83590
                     /locus_tag="LP245_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBL1518232.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            83698..84795
                     /locus_tag="LP245_000286"
     CDS             83698..84795
                     /locus_tag="LP245_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBL1518233.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            85102..>85548
                     /locus_tag="LP245_000287"
     CDS             85102..>85548
                     /locus_tag="LP245_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1518234.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        28137 a        15267 c        18127 g        24017 t
ORIGIN      
        1 tctctgttcc ctctttatca tggaagtgca aaaagtaata tagggattga taaccttata
       61 gaagttatta ctaataaatt ttattcatca acacatcgag gtccgtctga actttgcgga
      121 aatgttttca aaattgaata tacaaaaaaa agacaacgtc ttgcatatta agtagttcag
      181 ttttggagta caaaaagtga aaatgtaaac ctaaatgagt atcaaattgc aactgaattt
      241 gatactcgtt ttttattgtt aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag
      301 ttaaaatgta tataaaaatg cgaacgtgaa ataattattg taggaatgca aattggtgtg
      361 ttaaaatggt tacaatttac taagcaaaaa ggggtgcatt ttcctatgca atttcttgag
      421 ccaaaaaata agaacgctaa gtctgtggat tgggaaatat cagagcaagt aagggtgata
      481 gttaagcaat acgctgaata tgcagagcgt actgaaagcg aagcagtgga tgaattctta
      541 ttgaacattt tagacgataa gaagtttatt gaatggattg ccaacaagcg aagtaataag
      601 cggattgttg aaaaaatggg tatcaaagat agagtgggtt gatagacaat gaccaagctt
      661 aaaagattag ccacgaagga agatgaaatt gtagatgtta aaattccgat ttcaaacgaa
      721 gaattaaaag atagggctaa acaatatgat ttattaactc caaaacgatt tgcaacaagg
      781 tataacaaaa tgttgttctt gccaacgtct tttaaatgga acggttctga atatcccatt
      841 caatataatt actgcatcaa tccgttttgt tgtaattttg ggaaagaaca gcacaaattc
      901 aaagatgtaa aagggaaacc aagtcgatat aaaatgactg gtagttccaa agataaaggt
      961 cataaaggta tgtactgcaa tgacaatcct attggcagag gtgtatcgca aaactgtaca
     1021 gtaacccctt tatctaattg gtctgttgtt gaagaaatta aacgccttat agaaatcaat
     1081 agcatccaag atgttgagcc agattatcaa tttcataaag aaggctgctc ggaagaagaa
     1141 tcaaccccat tcaatgagcc gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct
     1201 caacgctatc aatgtaaggc gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa
     1261 accactactt atcaccaaca aaagaacacc attcttccaa tgttcgctaa gatggttgtt
     1321 ggaagggttt cagtcagtcg tacttgtgat attttaggaa ttggagttgg aacctactat
     1381 cataagctgg agtggctgta taggcgttgt ttggagtttt tagaacgata tgagacacaa
     1441 ccccttcaaa caaagaaatt taacgagatg tggcttaata cggacaagat gcactactac
     1501 ctaaataacg tccgtaagaa aggacaaggt tcaaagaaat atacggggtt tgaagacctt
     1561 aatatgcaaa cgtatatagt tgtatctgct gaggtcttat caagatatgt gttccgttct
     1621 gatgttgcct atgattggaa tatttcaatg gatgaattaa atgaagatac aagaaaattc
     1681 aaagaagacc atctcaatac ttttagtcgt aaaaatgata ggttagattg gtcttattat
     1741 ccacaagaac catccgctaa cgatagcgaa aataggaatg cttatcttca cgaattaggg
     1801 aaaattacta ataggagtag atttgtcgat ggtttaaatg ttgatgctcc ttatactaca
     1861 actgctcact attggttaat taaacaaatg gttaatgccg acgaatggcg aatgattagt
     1921 gatgatgact tctctattag aaacgccttt tatagagtat tcacgaaaga attaaggttg
     1981 agcgatgcac atcattttat ttgccaagtt aacaagacga aaagcagaaa acaatgctta
     2041 aaagaattcg gacaagcaaa agcagaactg ctcgattggg gagatatcag aggattcaaa
     2101 acaaagtttc tacggacttt ggcatctcat tatctaactg aattactaac aagtcatcaa
     2161 ttccacgaag aggctattag taaagatgga gaaagatatc gcaaatatgc cgataaccct
     2221 atcaaacatc cattagccac taaggataaa ggattttatt cagttgattg tagaacggat
     2281 ttatctgctc tggaaccaaa cgaaatcgca aagatgctat taaatgttaa tgaccattcg
     2341 accaatagct ttattcaaca gataagacgt tatatatcat ctcttgaaag accattaaca
     2401 acagctcgtg gtgataagaa gagctatatt tacgctaact tcaatccgaa gtatgctcaa
     2461 tttgcgatta caattctaag aacttactac aacttttgtc gcccttttaa atcagcggat
     2521 aaaaaggttt tgacacctgc tcaaagatta gggattacag ataaacaatt tgattggaaa
     2581 gatataattt atttcaaatg acaaaaagag cttggagtaa tcccaagctc ttgtgcttta
     2641 tctttactgt tcttcttcaa ttaacgcacc cgttaactca ataagttttt tctttcatat
     2701 acatgaaaat agtagttata cggattttta tcattcttta tccctttttg ggcaaatacc
     2761 tcattccatt cctcataatt cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt
     2821 atttttgtga tgtacatttt ctcaacataa gggaaaaaca aattataaat ctgttctcct
     2881 ccgaaaataa aaatttcttc ttcgttttta cataactcaa aaacatcttc tattgaatga
     2941 acaatttcac aaccattaaa ggtaaacccc ttatctctcg tcagaataat atttcttctg
     3001 tcaggtaagg ctcttccgat tgattcaagg ttcttcctac ctaatattat cggatgtccc
     3061 tttgtagtat ttttaacata ttcccagtcc ttgggaatcc tccaaggaat gtcattctct
     3121 ttgccaatca ctctattctt atccatcgca gcaatcaaag aaactttcat ttataacaca
     3181 gcctttttaa ctaatttacc atctaatttc ttatttctat caaaaaacct tttctcatta
     3241 tcctgcccgt tagttgaata agcaattttt tctataagtt atattatcat aataccacaa
     3301 aatcacaaat tttcattcaa ttatcatttt caattgcatt ttataaatca ttttgtatgt
     3361 aatttggtat gtaagttaaa atgaaaaaag tagtccattt tgaagtacat tttgtcattt
     3421 tgtactccaa aactgaacta cttacttgca tatatacgcc tttatagtgg agtactacat
     3481 ttacgagatt cggttagagt atcagaaaaa gaaaaaataa aagttacaga aatgtatact
     3541 tcaataaatg gtgaattatg taagattgat agagcttatt ctggagaaat tgttattttg
     3601 caaaatgagt ttttgaagtt aaatagtgtt cttggagata caaaactatt gccacagaga
     3661 aaaaagattg aaaatccgca ccctctacta caaacaactg ttgaaccgag taaacctgaa
     3721 cagagagaaa tgttgcttga tgcccttttg gaaatctcag atagtgatcc gcttctacga
     3781 tattacgtgg attctacgac acatgaaatt atactttctt tcttagggaa agtacaaatg
     3841 gaagtgatta gtgcactgtt gcaagaaaag tatcatgtgg agatagaact aaaagagcct
     3901 acagtcattt atatggagag accgttaaaa aatgcagaat ataccattca catcgaagtg
     3961 ccgccaaatc ctttctgggc ttccattggt ttatctgtat caccgcttcc gttgggaagt
     4021 ggaatgcagt atgagagctc ggtttctctt ggatacttaa atcaatcatt tcaaaatgca
     4081 gttatggaag ggatacgcta tggttgcgaa caaggattat atggttggaa tgtgacggat
     4141 tgtaaaatct gttttaagta cggtttatac tatagccctg ttagtactcc agcagatttt
     4201 cggatgctta ctcctattgt actggagcaa gcctttagaa aagctggaac agaattgtta
     4261 gagccatatc ttagttttaa agtttatgca ccacaggaat atctttcacg ggcatataac
     4321 gatgctccca aatattgtgc aaatatcgta aatactcaac tgaaaaataa tgaggtcatt
     4381 attattggag aaattcctgc tcgatgtatt caagattatc gcaatgattt aacttttttt
     4441 acaaatgggc ttagtgtttg tttagcagag ctaaaaggat atcaggttac cactggcgaa
     4501 cctgtttgcc agacccgtcg tctaaatagt cggatagata aagtaagata tatgttcaat
     4561 aaaataactt agtgcgtttt atgttgttat ataaatatgg tttcttatta aataagatga
     4621 aatattcttt aatatagatt tgaattaaag tggaaaggag gagattgtta ttataaacta
     4681 caagtggata ttgtgtccta tttgtggaaa taaaacaaga ctacgaatac gagtggatac
     4741 tatacttaaa aatttccctt tatactgccc caaatgtaag aacgaaactt taattaatgt
     4801 tcaaaaaatg aatataataa caatcaaaga gccagacgcc aagacgcaga gccgataatt
     4861 tgagaaatga aactctcatc ttatcggctc tttttgttta tctgaatttt actgactagc
     4921 cttcaatatt tcttgcttca ttgatacctt ttgctagtgc ttccattaag gatagttctt
     4981 tgtctgtaaa gctatccatg tatttttcta cctgtaacct tcgagtgctt ttaatcaaat
     5041 tatctgtagg taagaaaaat tcatcaatag atacatggag taatgataca agatcataca
     5101 gcacttgtgt acttgggtgt tgtcctttgt tttctatatt tgttaaataa cgtgggtcaa
     5161 tttcaatcat tgttcccact tgttcacgag tgagaccccg tttcattcga gcctctttaa
     5221 tcgctaaacc aacggctcta aaatcgtatt tatcttcttt tttacgcata ctaaatcacc
     5281 tctatacatt ttactgttcc tatataacca taaacaggta tagaaaaaca tgttatatag
     5341 tttatgagtt cctatagaac actgtggaat ttattaatgc gatgaatcca atttcaaata
     5401 gaaaggtcgc tgattttatt tacctataca actttataaa atttagtcat actcctagaa
     5461 agtagataaa attggcgact taatggaggg aaaagtcgcc atgagaaaga taatctgtca
     5521 tctagttctc ttaattaagt tcttatcaaa aaaacttatc cacctgtact ggatagatat
     5581 gaccatcaat gtggttttgc agattacata gatagaaaaa tcaaagcata tgaacagaga
     5641 aaacaatctg tttatgtgct tttttggtca cttaataaat atcttttagg atttctcttc
     5701 atttatgcaa caaatccccc gttcgtgtcg gggtttagta tgaagggaga taaagaagca
     5761 catgccactc cctttcacga cagaaagggg gtgaaaagca tgaaaccatc ttcttttcaa
     5821 gaaaccatag aaaatcagtt tgactatatc tgcaaacaag ttattgaaga tgaacgaaaa
     5881 gattacttca aacatctaga cagactatca gcaaaagaag tctcgttttc tgatatagat
     5941 aactaccttg tcaactcttt ttctactgtt gatacgtacg tcactgattt ccaactattt
     6001 aaattatttg gattaagaat caatgttgaa agtgatttat taagtgaagc cctgcgtcat
     6061 ctttcagaga aaaaacggaa cattatttta cttcattact ttatggatat gagtgatgtg
     6121 gagattgcgg agttactaaa tttgaatcgt tcgactgttt atcgtcatcg aataagtgga
     6181 ctagccatga ttaaagaatt catgaaggag tgtaaagaat gaaaacagct tatccaaggg
     6241 ttcccttccc cctcattgta aaggcgacag atggcgacgt ggaagcaatt aatcagattg
     6301 ttaaacatta tcgagggtat acctcaaaac gttcattacg tcgcatgaca gacgaatatg
     6361 gaaattctca tatggttatt gatgaaaccc tacgtggcag aatggaaacg aaactcatct
     6421 ctaagatttt atcgttcgaa attaaatagt cccatttttt cgtggaagcg tgtcgaatcg
     6481 tatccacgct tcccgatttg ggaggtttgt tattccatca aagcatattg tgtgttcagt
     6541 aggttttgat aggctaacaa gccaaacgtt ctttgacaac caaataaagg caatcgaata
     6601 cgtttcggta agaaaagagc tgatgaacta acacgccatg acctacaaaa ttagtgagcg
     6661 attcatgtta gtaattcgaa agtaatcttt agcaggattg ctgccatgac tttcttatcg
     6721 tgataatgat actcccgtat agccatagtc cgagcgttag aagcgtcaca ggcaatgggt
     6781 acggctacat gagaaccatg cagaagtgaa attcctgtga gctttgctag agctgttcga
     6841 ttgctaagat attcttctct tgtcagtgta ttattataaa actatttgat ataattatag
     6901 gtgaatattg gagttttcct agcctataat tgggaaagga gtaataatga taacggtcac
     6961 aaaaaaggat ttagttgagc taggatatgg aacttctttt tcagcagaca tcataaaaaa
     7021 agcaaaagaa ttgatgatta caaaagggca tatctactat caatctcgaa agctagatag
     7081 agtccctcgt gaagctgttg aagaaattct aggaattcgg ttttcaaatg aaaacaggtc
     7141 tgagtagttt ttgcacagta aggagtaaaa actatggtta aagacccaat aaaaaaagca
     7201 aagaatggaa cctattattt tcgtgcaaat ctaggttatg attctaaagg gaaaaaaatt
     7261 caaaaatatc gtagtggatt cactactaaa aaagaagcaa gagaagaata ttcgaaactg
     7321 ctattgatga aaccagaaga attaagtgag aataaggata aaatgacgtt taaacattat
     7381 atctttgaaa ttttccttcc atggtataag acacaggtaa agctcagaac atatgaaaat
     7441 cgcttaccaa ctattaagaa gcatttctct tattttgata aaatggctgt ttccgatatt
     7501 gagcctattg atgtgcaaaa ttggcaacta aaattatcaa agaagtgtaa gtcttcttat
     7561 gtaagagctg ttcaaggact attttcagtt gctatggatc gagcaattgt ccttgggata
     7621 accaccacaa atccatctaa gattattggc aatgtgaaaa agcaaaagtc taaaattgaa
     7681 ttttggacaa aagaagaatt tgaaaaagta atctctctaa tttacaaaga agattactat
     7741 caacactttt tatttatctc tctgtggttt ttatttatga ctggaatgcg aattggtgaa
     7801 gctactgcca ttcaatggga agatattgat tttgactcag gagtactaac catcaacaaa
     7861 acactctatt acaagaatca atcgaattat agatttgttg aaccaaaaac aaaggcgagc
     7921 gttcgtcata ttgtattaga taaatgcaca ttaacttatt tatccgaatg gaaggaagta
     7981 caacaaaatc taattcagac agactttgta atgagctata acggtattcc tacccaaaaa
     8041 catacactat catatgctat tgaacgctat gctaagctgg ctggtatcca tcgaatcaga
     8101 atccatgggt tacggcattc tcatgcttcc ttgttaatca gtatgggaga aaatccactt
     8161 atcattaaag atcgtctagg acacgaagat attgagacga ctttaggaac gtatggacat
     8221 ctttatccta acagtaattt cgaggtagct aacaaattaa atggagccat ttcctttaaa
     8281 gaagcaaaac aaaattatga tacttcacca aagaatcaat ttactgtaga ctacttgcga
     8341 aacaaagaaa tgaaaaaagt gcaataaaag tgcagtaaaa agataagaag agccagaaac
     8401 ccttggtata agaggatttc tagctctcct acaactattc ccactccact gttgctggtg
     8461 gtttagaagt gatgtcatac acgatacggt tgacgtgggc tacttcgttt acgatacgta
     8521 cagagatttt ttgcaagact tcccatggga tacgggcaaa gtcagcggtc attccgtcga
     8581 ttgaagttac agcacggata ccgactgtgt agtcgtaagt acgtccgtca cccataacac
     8641 cgacagagcg gatccctgga agaacagtga aatattgcca gatatcacgg tcaagtccag
     8701 cagctgcgat ttcttcacgc aagatagcat cagattcgcg tacgatttct agcttgtctt
     8761 cagtgatttc gccaagaaca cgaataccaa gaccaggacc agggaatggc tgacgccaaa
     8821 cgattgaatc aggcatgcct aactgagtcc ctaattcacg gacttcgtct ttgaataatg
     8881 tgtttaatgg ttcgatcaat tcaaattgca tatcttctgg cagtccacct acattatggt
     8941 gagatttgat cgtctgtgct gtttctgtac cagattcgat aacgtcagta tacaacgttc
     9001 cttgtgctag gaaagagacg ccttcttcac cagcaagttt tgttgcttcg tcatcaaaaa
     9061 catatacgaa ttcattccca atgattttac gtttttgttc tgggtcagat acacctttca
     9121 acttgtctaa gaagcgatct cttgcatcga ctttgatgat gttcaagccg aattttccgc
     9181 ctagactttc cattacttgt tccgcttcgc ctttgcgtag cagaccgtgg tcaacaaaga
     9241 tagatgtcaa ttggtcaccg atcgcttttt gtaaaagaac cccaacgaca ctagaatcaa
     9301 cgccacctga aagaccaagc aagacttttt tgtcaccaac ttgttcacgg attttttcta
     9361 cttgcatatc gataaagtta tccattgtcc agttaccttc acagtgacaa acatcaaagg
     9421 caaagtggcg cagcaattcg attccgtatt cggaatgacg tacttctgca tggaattgga
     9481 taccataaaa attacgtgtt gtgtcttgga tagaagcaat cggacaatct ttgcttgttc
     9541 cgactgtttc aaagccttca ggaactttag ttaccaagtc accatggctc atccatactg
     9601 tttgttgttt tggtgtttct ttaaacaaga cagcttgatc gcttgttact tctaacaagg
     9661 ctttcccata ttcgcggttt ttagcaggct ctacggaacc gccaagtttg tacgtgatca
     9721 attgcatacc atagcaaatc cctaatacag gaatacctaa attgaagatc tcaggatcga
     9781 tcccaaatgc attctcatca tatacactgt ttggtccgcc agaaagaatg attccctttg
     9841 gattcatcgc ttttacttct tctgcagtaa tgcggtggct caataattcg gaaaagactc
     9901 caagatcacg aatacgtctt gtgatcaatt ggttatactg actaccgtag tctaatacga
     9961 taatcttttc aacgttcgtc atatcggcaa cgtttgtcaa atttattacc cctatccctt
    10021 taaattttat ctcaaaatag tcaaactatt ttaaaatgct aatattttcg catgaaaatc
    10081 gaatcgatga tatgattttc agttttatgg agaattatat cggctcttcc tcgtgtaggc
    10141 aagatatatt cctgtaaatt tttcaaattc acatttttcc atacatcttt tgccatttta
    10201 aaggcttctt cacgatctcc gatagcaaaa cgataataat aattctctgg attttggaaa
    10261 gccgtatcca gtaacgcacc aaaacgatcc aaataccatt tttcgatcag cacgggatcg
    10321 gcatcgacat agacagaaaa atcaaaaaag tcgctgacgt agatttgctg attcgcaggt
    10381 aattgaagcg tattgatccc ctcaacgatc aagatatcag gctgctggat caattcgtac
    10441 ttgtctggaa tgatatcata cacatcatgt gagtaaacag gtacttttat ctcttcctga
    10501 ccagatttta cacggttcaa gaaatcgatc agcatctcca tatcataact ttcaggaaat
    10561 cctttacggt ccatgattcc acgctctttt aatatacgat ttggataaag aaatccgtca
    10621 gtcgtgatca gctgaacgtt tcttcgtttg aaggtacgag acaaaatcgt ctgcagcagt
    10681 ctggctgttg tactttttcc aacggctaca cttccggcga tcccgataat aaaaggcggt
    10741 acttctacgt atttatgaag aaataaacct ttactcaaga acaaagattc aaattctttc
    10801 atataaagat aaatcagatg agcaagaggt acatagatat ctcgaacatc ctgcatggaa
    10861 atgcggtcat tcaaactttt gatattatct agttcatctt gtgtcaaagg tgcttgccca
    10921 ttacgataaa attctcgcca ttcttctctt gccacacggt agtagttcat tggatcattc
    10981 atattagcct cctgcgttct cccatcaatg gaactatttt aacacaaaat aaacgcaaac
    11041 cccaccactt aagagagatt gccgatcttt ttgtataatc tttataatag aaagaaacgg
    11101 agtcttattc ttgacttgcg cacggataca taaaaggata gactgttgtc atgaaagaaa
    11161 tgagaaggat ggaagacatg acaaatcatt actattctga acgcccagat acggcgcacg
    11221 attttgaaca atgggctttt gagttaaaag gcagaacctt tcaatttgta acagattctg
    11281 gtgtattttc acgtgaaaca gtggattatg gttcacgtgt cctgattgat gctttcgatt
    11341 gggaagagtt acctgatgaa ggaaagatct tagatgtggg atgcgggtat ggaccgattg
    11401 ggttagcttt ggcatttgcg acacagcggt ttgttgaaat ggtcgacatt aatgaacgag
    11461 cggtaagtct agcgcaagga aacgcaaagc gtaaccaaat cgaacatgtt gatatccatc
    11521 aatcgaatat ctatgaagca gttcatgaag aaacctatgc agctatcgta agcaatccgc
    11581 cgatccgtgc tggaaaaaaa gttgtacatg aaattttgac aggcgcatat cctcggttga
    11641 agaagggcgg tacactgaca attgtgatcc agaagaaaca aggagcgccg agtgcgcaaa
    11701 agaaaatgga agaaacattt ggtaatgcag aaatcgtcac aaaagataaa ggatattata
    11761 tcatcaaaag tgtgaaagaa taactagctg aaaaatagtg gagcgacgaa agagtggaac
    11821 tgggcgtgca tgtacgggta cgtatcagtt ctttttttgt tgagaagttt ttaaaaacaa
    11881 agaactattt tttcttcaaa aagaaatagt aggaacagag tcgttgtttt ttacgataaa
    11941 ataaataaga tacagaactt gtatagaagg ctgccaagtc ggtagataaa ggaggttttt
    12001 atcaaaaaac atactttcct tttttctcta ttcttttctt gggggttttg gtacactgat
    12061 agggaattta gatagaaggg agccaatagg atgaagctga ccatcagaga tatcgcagaa
    12121 atggcaggcg tatcagtaac aactgtctca cagattttga ataacaaagg aagcagattt
    12181 agtgataaga caagaaaaaa agtgttgtcg atcgtgaatg aacatcatta taagcccgat
    12241 tatttcgctt caaatgtgat caatcgacat tcaaagacca tcggaatgat cgtccctgat
    12301 gtcactgatt tcttcttctc caaactgatc gaaggtgtag agagctattt gaatcctttg
    12361 ggctatgtga tcatgttatg caattctcgt catagccaag aaaatgagat caagtattta
    12421 caagagcttt cccaccgctc agtggacgga atcttgctgg ccacaccaaa tattttacct
    12481 gagaaatatg cattagacag cggtttttat caaaaaatgc caatcatttt aatcgatcgc
    12541 ggattgaatc gtcgggataa cggacggctt atcgtaaagg aatatgaggg cgcctatcaa
    12601 gctgtttcgc tgtttattga aaatggccat acgaagatcg gcatgctgaa ggaaaccact
    12661 ggatactatc aattagaaga acgtttcaac ggatatcgtc atgcgctgaa agatcatggc
    12721 ctgcctttta atgggaaatt tgttgaacat ggagagttga ctgtccaagg tggatatact
    12781 gcatcaaaaa aattactcaa acataaagat atcacggcta ttttttgcgg gaatgatgcc
    12841 atggcgatcg gatgctatca ggcgatcgat gaattgggca aaaaaatccc agaagatatc
    12901 tcagtcatag gattcgatgg attaaagctg tcagaataca tgattccgca attgacgaca
    12961 gtgcagcagc caagttttga tattggattt tatgctgcac gtttcctgat cgatacgatc
    13021 gaatttcctc aaagaaaagt tccgaacaaa gtgttcgaaa caaaattaat tattcgtgag
    13081 agcgtaaaag tattgacaaa gggctaactc ggcggtatat tgcttatgta agcatttaca
    13141 aaggctagtt agtgcttttt ttatttttag taaaccagtt tactaaagtg gtttaccttt
    13201 cctaaaaata atgtataata ccgaatgaag acaaggagga tcaggcaatg cgaatggtgg
    13261 atctgattga aaaaaagagg gatggaaacg agctgtcgaa agaggaaatc gagtacatcg
    13321 tcacgaacta tacgaatgga aagattccag attatcaagt cagtgcatta ttgatggcaa
    13381 ttttttatca agacatgaca aatgaagaaa tcacgaactt aacattggcg attgctaatt
    13441 ctggtgatgt catcgatttg agttctcttg aaggaataaa ggtagataag cattcgacag
    13501 gtggcgttgg tgacacgacc acattgattt tagcccccct agtagctagt gtcggagtga
    13561 cagtggctaa aatgtctgga cgcggtctag gttacacagg tggtacacta gacaagctag
    13621 aagcaattcc cggatttcag atcgagcttt cggatgaaga atttgtacgc attgttaatg
    13681 aaagtaaagt agcggtaatt ggtcaatcag gaaacttggc accggcggac aaaaaattgt
    13741 atgccttgcg tgacgtcaca gcgaccgttg attctcttcc gctgattgcc agttcgatta
    13801 tgagtaaaaa aatcgcggca ggagcagatg caatcgtttt ggatgtgacc actggagacg
    13861 gtgctttcat gaagaacatc gaagatgcaa gacgtctggc aaagaccatg acgagcattg
    13921 ggaaactggc taaccgagaa acagtggcgg ttatctcaga tatgtcagaa cctcttggcg
    13981 aagctatcgg aaatagtcta gaagttgtcg aggcaatcga aacattacaa ggaaatggtc
    14041 cagaagatct agtagaaatg tgctacgcct taggaagcca aatggttgtt cttgctggca
    14101 aagctaagac aaccgatgaa gcaagaacgt tgcttcaaga agctctggaa tcaggtaaag
    14161 cgttagcaaa attcaaagaa atgatccaaa atcaaggggg agacccagcg atcgtggaac
    14221 atccagaacg aattttgact gcacgctaca caatggagct tcctgctaaa caaagcggag
    14281 ttgtgtcaaa aatcgtggca aatgaattag gaattgctgc aatgatgcta ggtgctgggc
    14341 gtaaaaccaa agaagaagat attgatcacg ctgttggatt gaaactgcat aaaaaaattg
    14401 gtgacactgt gacaaaaggt gagtcactat tgacgatcta tagtaacgac gaagaaatca
    14461 cttctgtcat tgaattatta tataaaaata ttgaaattgg tgaatcggca atgaagccaa
    14521 cgttgattca tgacatcatc acagaataaa ggaaaaaagc ggactttacc gttttaaaga
    14581 aaaggggaaa agaaatggaa ctaaaccgaa tgatcgacca tactattttg aaagcagacg
    14641 catctaaaga agctgtgatg caaattatcg aagaagcaaa aaaataccat ttttattctg
    14701 tctgcatcaa tccagcatgg gttgcgctag cgaaagaaca attacaaggt gagccagtag
    14761 ccgtatgtac agtaatcggg tttcctctag gagcaaacac acccgagaca aaagcatttg
    14821 aaacaacaga tgccatcaat aacggtgcag atgaagtcga tatggtcatc aatatcggtg
    14881 ctttgaaatc aaaggatgat caacaagtcc aaaaagatat cgaagcagtt gttgaagcag
    14941 caaaagatcg tgcgcttgtc aaagttatta ttgaaacatc gttattagat agagaagaaa
    15001 tcatccgagc ttgcgaaata gcaaaagctg caggcgctga ttttgtcaaa acatcaactg
    15061 gtttctcaac aggcggagca aaggtagagg atgtccgttt gatgcgtgaa actgtaggac
    15121 cagaaatggg tgtcaaagct tccggcggta tccataacga agaagaagca atggcaatga
    15181 tcgaagctgg tgctacaaga atcggaacaa gcgcaggagt agcaatcgta tctggttcaa
    15241 ctggtgaagg ctattaattt tttcaaagga gaagctcatg gcagaactca aacaagaatg
    15301 gatcaacaca gctattgaag cgttagataa agcctatgtt ccttattccc attttccggt
    15361 aggcgcttgt ctcgtaacgg aatcaggcaa gatttatcaa ggcatcaaca ttgagaatgc
    15421 atcatttgga ttaacgaatt gtgccgagcg cacagctttt ttcaaagcag tatctgaagg
    15481 agaaaaaaca tttacgcatc tagtcgtagc ggggcacacc cccgatccta tctctccttg
    15541 tggtgcatgt cgacaagtaa tggcagaatt ctgttcccct gatatgccgg ttacgctagt
    15601 aggagacaat ggtgtgacga aggcaacgac cgttcgtgca ctgctgcctt atgcatttac
    15661 tgaaaaagat ctataactca tgttcattca gtcagctgac tgttgaaaaa taaaacaatt
    15721 attttaggag gctttacaga aatgaaaaaa gcaaaattat ttggtttagg tgctgtcgca
    15781 ctagcagcag ggttattttt aggtgcatgc ggcaacaacg gctctactga ttcatccggt
    15841 ggcaaaagct catcagacac aacaactgca gcattgatca cagacacagg tggtgtagac
    15901 gaccgttcat tcaaccagtc agcttgggaa ggactagaaa aatgggggaa agatcaagga
    15961 ctttcacgag gaaatgatgg cttccaatat ttccaatctt caaatgaatc agattacatc
    16021 ccaaatattg accaagcatt gaatgctgga ttcaaaacga tttttggtat tggttataaa
    16081 ctaaaaccag cgatccaaga acaagcaaca aacaatacag gtacgaactt tgttattatc
    16141 gatgatgtca tcgatggatt agataacgtt gtatctgcaa ctttcaaaga caacgaagct
    16201 tcttatcttg caggtgttgc agcagcttat acgactgaaa caaacgtagt cggctttatc
    16261 ggcggtgtaa aaggtgaagt aatcgatcgt tttgatgctg gattcaaagc cggtgttgat
    16321 gcaggtgcga aagaattagg aaaagaaatc aaagtattga atcaatatgc tggtgacttc
    16381 tctgctccag ataaaggacg ttcaattgct caaggtatgt atgcacaaaa cgcagatatc
    16441 atcttccatg cttcaggcgg tacaggtaac ggtgtattcc aagaagcaaa atcattgaac
    16501 gaatcaggcg acaaaaaagt ttgggttatc ggtgttgacc gcgaccaatc agacgaaggc
    16561 gaatacacat taaacggcga aaagaaaaac ttcacattga catctacact gaaagcagtt
    16621 ggaacagtag tagaagattt ggcacaaaaa tcagcggacg gtaaattccc tggcggcgaa
    16681 cacactgttt atggattgaa agaagacggt gttggtctaa cagaaggaca actttctgac
    16741 gaagcgaaaa aagcagttga tgaagcaaaa gaaaaaatca tttcaggtga cgtaaaagtt
    16801 ccagaaactc ctgaagaaaa ctaaaaccat ttctatagcc ttgttagaca catgtttgac
    16861 aaggctatgg tttgattaga acaagaattt ttcatttatc caagctgcct tgtgacagtt
    16921 tggataaggg aacaactccc tgaagtaatg tttgtttcaa aagaagaacg ctcactaagc
    16981 gtgaatctta gtcaatcgtt gccctagata gaaatcgtta ggatgtgaaa aaaaggtggt
    17041 tcaagaaaat attgtcatag aaatgcagaa tattaccaaa gaatttggaa cattcaaggc
    17101 aaatgacaac atcaatttac aagtaaaggc aggagaaatt catgcgttgc ttggagaaaa
    17161 cggtgctggc aaatctacat tgatgaacgt gctttccgga ttattagagc cgacatcagg
    17221 gaaaattttg atgcgtggga aagaagtaaa gatcacaagt ccgaccaaag ccaaccaatt
    17281 agggattggg atggtccatc agcactttat gcttgttgat gcctttactg taacagaaaa
    17341 catcgtgttg ggaagcgagc ctagtcgcgc agggatgctt gaccataaaa aagcacgaaa
    17401 agagatccaa aaagtttctg aacagtatgg attgtcagtc aacccagatg cttacgttcg
    17461 tgatatttca gttggaatgg aacaacgggt agaaatttta aaaacacttt accgaggagc
    17521 agatgtactg atttttgatg agccgacagc tgtattgacc cctcaagaaa ttgatgaatt
    17581 aatcgtgatc atgaaggaat tagtcaaaga aggcaagtcg atcattttga ttacgcataa
    17641 gttagatgaa atcaaagcag tagctgaccg ctgtacagtt atccgccgtg gaaaaggaat
    17701 cggtacagtc aacgttaaag acgtaacctc acaacaatta gccgatatga tggttggaag
    17761 aacggtttca ttcaaaacga tgaaaaaaga agcgaagcct caagaagtcg ttttgtctat
    17821 tgaaaatcta gtggtgaaag aaaatcgtgg attagaagcc gtgaaaaact tgaacttaga
    17881 ggttcgtgct ggcgaagtac ttggtatcgc tggaatcgat ggaaacgggc agtcggagtt
    17941 gatccaagct ttgactggtt tgcgaaaggc agaaagcgga catatcaagc taaaagggga
    18001 agacatcact aataaaaaac cccgaaaaat cactgaacat ggtgtaggac acgtgccaga
    18061 agaccgtcat aaatacgggt tagtcctaga tatgacatta tctgaaaata tcgcactaca
    18121 aacctatcat caaaaacctt acagtaaaaa cggcatgctg aattattcag taatgaatga
    18181 acatgccaga gaattgatcg aagaatatga tgttcgaaca acgaatgaac ttgttcccgc
    18241 aaaagcttta tcaggcggaa atcagcaaaa agcaattatc gctcgtgaag tcgaccgaga
    18301 tcctgatctg ttgattgttg caaatccaac tcgtggactg gatgtaggtg cgatcgaatt
    18361 tattcataaa cgtctgatcg aacaaaggga caaatacaaa gcagtgttac tgatcagttt
    18421 cgaattagaa gaaattttaa atgtttcgga tcgtattgct gttatccatg aaggagaaat
    18481 tgtcggtatc gttgatccga aagaaacatc tgaaaatgaa ttaggtctat tgatggcggg
    18541 ctatacctta gaagaagcac gaaaagagtt agaaaagggg gctggcgcac atgaatgatc
    18601 gcagcgaaaa attccgtaat ttattagtgc ctgtactttc agttgtttta ggattgatct
    18661 taggcgcgat attgatggct gcttttggtt ttcagcccat ccaaggttat tcttctatgc
    18721 tagatgcagc ccttggttcg caaagaggga taggtgaaac gttaaggcaa gcaacgccgt
    18781 tgatttttac agcattaggt ttttctgtag ctaactcagc tgggtttttc aatattgggc
    18841 tttctggaca agcactttgc gggtggatcg tcagtgtctg ggtggcactt gcgtttccag
    18901 atctgccaaa agttgttttg cttccgttat gcgtgatctt aggtgcctta gctggtgcga
    18961 tggcagcggc tgttccaggt ttacttcgag cattttttgg aacaagtgaa gtgatcgtaa
    19021 caatcatgat gaactatatc ttattatacg taagcacatt tgctttacat gaagtgatgc
    19081 ctgaaagcta tcgctcaagt ttggactctt ccaatatgat cagtcaaaat gcctcactgc
    19141 ggttaccatg gttaacacaa gcttttggcg gctctcgcgt aaactcagga ttatttttag
    19201 caatcatcgc gcttattttc gtttggctgc tgatgaagaa aacgacttta ggatttgaaa
    19261 tccgttctgt tggattgaat ccttttgctt ctgagtatgc aggaatgagt agtaaacgta
    19321 cgatcgtttt gtcgatggtc atttctggcg ctttggcagg gcttggcggt gtggttgaag
    19381 gattaggaac gtatcaaaac ttctttgttc aaacgacttc gctatctatt ggatttgacg
    19441 gaatggctgt ttccttgctt ggttctggat cagcaatcgg tattctttta tcagcgatct
    19501 tgttcagtat tttgaagatc ggtggacttg gcatgcagac aggagcaggt gttccgtttg
    19561 agatcgtcaa tgtatcgatt gctttgatta tcttctttgt cgggatcaac ttcctgattc
    19621 gtttcgtcat ggctaaagtc ttccaaggga aaaaacaaga agagatcgtt gcgacaatag
    19681 aatcgaaacc aacgaatcaa aaccatgaag ggggcgaact ataatgtcga ctatcgaatt
    19741 aattgccttg atccttactt ctacactggt ttattcaaca ccgctaattc taacgtcact
    19801 aggcggaact ttttctgaac gaagcgggat cgtaaacgta gggctagagg gaatcatggt
    19861 catgggtgct tttagttcca tcgttttcaa cttgacgatg agtccatcac ttggttctat
    19921 gacaccatgg atcgctattt tagtgggtgg cgtcgtaggt atcctatttt ctctgattca
    19981 cgcagtagca acagtcagtt tgcgtgctga ccatattatc agcgggacag taattaatct
    20041 gatggcacct gctttaggtg ttttcttgat caaagcatgg tatggtaaag gtcaaactga
    20101 taacatcacg cagaatctgg ggtatttttc tttcccagga ttagcagata ttccggtcat
    20161 tggaccaatt ttctttaaaa atacattctt acctgcttat tgtgctattt tgattgctgt
    20221 cctagcttgg gtgatcatct tcaagacgaa attcggcttg cgcctccgtt cagttggtga
    20281 aaatcctcaa gctgccgaca cattaggtat caatgtatat gctatgcgtt attcaggcgt
    20341 actgatttct ggcttgttag gcggtatggg cggtgctgtt tttgctcagt cgatttccgg
    20401 taacttttca gctggtacga tcgttggaca agggttcatc tccatggctg ctatgatctt
    20461 tggtaagtgg aatcctttag gggcaatggg tgcctcattg ttctttggtt ttgctcaaag
    20521 cttgagtatc attggcgcac aattaccagt tatttcttcg attccgccag tattgctgca
    20581 aattgctcca tatttgctga caatcattgt gctggttgtt ttcttaggga aagcttctgg
    20641 tccaaaagca aacgggaaga actatatcaa atcaaaataa tcttttagcg aataaaaagg
    20701 gtgggttacg ggaagtgttt ttcgtctcgc cctttttgtt ttaaaggcaa taaaaataaa
    20761 aagaaagaag gaataatcat gtttaaacgc gtacatctga tcgtcatgga ttcagtagga
    20821 attggagaag caccagatgc cgataagttc ggtgatgttg gttctgatac attaggacac
    20881 attgcgaaag aagcaggatt gaacgttcca catttagagc agcttggttt aggaacgatc
    20941 cgtcctcttg aaggtgtgga atcagtgaaa gatcatcaag gctatgcgac gaaattagaa
    21001 gaagtttctg tagggaaaga tacgatgaca ggccactggg aaatcatggg attgaatatc
    21061 aaaactccat ttcgtgtgtt tcctaatgga ttccctgatg atctgatcaa acaaatcgaa
    21121 gaattttctg gccgtaaagt cgtatgtaac aaaccttata gcggaacagc tgttattgac
    21181 gattacggtg aacaccaaat gaaaacaggc gatttaattg tatatacttc tgccgatcct
    21241 gtccttcaga tcgcggcaca tgaagaaatc attcctttag aagaattata tcggatttgc
    21301 caattcgttc gtgatataac aaaagatgat ccgtatatga ttggccgaat cattgcacgt
    21361 ccgtacgtgg gtgaaccagg agacttcaca cgaacaagca atcgccatga ttatgcgttg
    21421 aatccattcg gacacacagt ccttgattct ttgaaagaag caggaaagga cgtgattgct
    21481 gttggaaaga tcaacgatat tttcaacgga caaggaatca ctgaatctgt ccgcacgaaa
    21541 agcaatatgg atggcgttga ccagctgctg aaagttatga aaaacgattt ttcaggaatc
    21601 agctttacca atttagtaga ttttgatgca ttatacggtc atcgtcggga tgtagtcggc
    21661 tatgcgcatg cgattgaaga atttgactta cgaattccag aattgcttga agcgatggaa
    21721 gaagacgact tgctaatgat tacagccgat cacggaaacg atccgacgtt tactggtacc
    21781 gatcatacgc gagaatatgt accgttattg gtttacagta aaaaaatgaa agaacaaggg
    21841 gcattgcctc aaggatatta ttcagatatt tcagcaacga ttgctgagaa ctttagtgtt
    21901 tcttcgactg aaaatggcga aagcttcttg aaattattaa aataatcttt ttaaatagga
    21961 gaaagcaaat gaccaagtta agcgagatgt tacaagaaac gacccagttt atccttgata
    22021 aaggagtaaa agaaattgat tttggtttga ttctaggttc aggattaggt gaattagcag
    22081 atgaaatcga agatgctgta atgatttctt atgatgagat cccgttcttt cctgtttcga
    22141 cagtagttgg gcatgcagga aagctagttt atgggtctct ggcaggcaag aaagtgttag
    22201 ccatgcaagg gagattccac tactatgaag gtcattccat gcaaacagtg acctatccag
    22261 tacgtgtgat ggccggacta ggggcccatt cagtcattgt gactaatgca tgtggtggtg
    22321 tcaacgaatc atttgtacca ggagatttga tgctgattac cgatcatatc aattttactg
    22381 gtgaaaatcc tttgatcggt ccgaatgaag atgcaatggg ccctagattt ccagatatga
    22441 gtcaagctta tacgcctgac tatcaagcaa cagcaaaagc agcagcagaa aaactaggtt
    22501 tggatcttaa agaaggcgta tatatgggct attctggacc aacttatgaa acgcctgcgg
    22561 agatccgaat gtctcggaca ataggagccg atgcagtagg gatgtcgact gttccagaag
    22621 tcatcgtagc agctcacagc ggattaaaag tgttaggaat ctcttgtatt accaacttag
    22681 cagcaggtat gcaagcgaat ctgagccatg aagaagttgt agaaacaact cagagagtca
    22741 aacaatcttt taaagcattg gttaaagaaa cattgacatt attgtaatag gaggaacaat
    22801 aaaatgagtg tgcatattga agcgaaagaa ggcgagatcg ccgataagat tttacttccg
    22861 ggagatcctt tgcgagctaa atatattgcg gagacttttt tggaagatcc agtttgttac
    22921 aatcaggtac gcggtatgtt aggctttacc ggcaaatata aaggagaacg tatttctgtt
    22981 caaggaacag gaatgggaat gccatcagcc accatctatg cccatgaatt gatccagtcg
    23041 tatggtgtaa agaaattgat tcgagtaggt acatgcggtg cattgtcaaa agacgtccat
    23101 gttcgtgatt tagtactagc acaaggtgca gcgaccagtt cttcgatgat cgaaaaaaat
    23161 ttccaagcct ttcattttcc tccaatcagt gatttcaatc tattactgaa agcatatgag
    23221 atagctaaag aaaagggcta tacggttcat gtaggaaatg ttctttcgga agattctttc
    23281 tacaaagatg atttgacaga gacgttccaa ttagctgaac ttggcgtttt aggagtggaa
    23341 atggaagcag cggctcttta ttacttaggc gcgaaatacc atgtgcagac attaagtttg
    23401 atgaccgtta gcgaccattt gatcaccggt gaagaaacaa cagctgcaga acgtcaatct
    23461 acgttcaatg aaatgatcga agtaggattg gaaacagcga tagcagaata agaaggaaat
    23521 gaaaaagctg ccctgcatta agtaataaga acatccaagc aaaaatagct cctcatgttt
    23581 ttgacttggc tggacttatt attgcaaatg taagcttttg aacaccgttt accaagaggt
    23641 tgtgaatctg ccgtttaact ctgagtcaca aggaacaatt tcaaaaaaca gcttttcatg
    23701 tttgatgaat attgtgactt gtgaccgaga agttggcagg agaaaaccgt ttatacgaaa
    23761 aaagggactg tgacaaatcg tgtcacagtc ccttttttat agtgtttttt ataggtagta
    23821 ttttttagca actgttaagt catcatttaa ttcataaaca agtggttgac ctgttggaat
    23881 ttcaagatcc atgatgtctt cgtcagagat accttcgata tgtttagcta gggcgcgtaa
    23941 tgagttacca tgtgcagcta ctaaaacagt tttgttgtct agtaatgctg gagcaatttc
    24001 atcttgccag aatggcaaag cgcgttctaa tgtcactttc aagttttctc caccaggaat
    24061 atcgcgtttg tctaacattg cgtaacgacg gtcatttgct gcagaacctt cgtcagtttc
    24121 ttccattaat ggaggaagag tatcgtaaga acgacgccag atgtgcactt gttcgtcgcc
    24181 gtatttttca gctgtttctt ttttgttcaa accttgtaat ttaccatagt gacgttcgtt
    24241 taagcgccat gatttgattt gtggtaccca aagttgatct gaatattcta agatcaagtt
    24301 acatgttttg attgcacgag ttaaaacaga agtgtaagca acatcaaatt cgattccagc
    24361 ttctttgatt ttgcgtccgc cttcttttgc ttcttcgatt ccttctggtg ctagatttac
    24421 atcagcccaa ccagtaaatt ggttcaatgc attccattca ctaagaccgt gacgagaaaa
    24481 aactaatttt ggcatgttta gctctccttt taagataggt ttatatttct gaaattttca
    24541 gttctgtttt attgtacaat tttttggaag agatttccat cgaaaaatta gataagattc
    24601 tatgagaaaa caagtagaga atataaaaaa acgaacagtg cccacgcaac tgttcgtttt
    24661 taggtattag atgcataatt gctcgatttc tttttcaggt aaattgatat atttataaca
    24721 tgttccaact gaaacaccgc attttgaaga aataaattgg atcgtttctt ttttttcata
    24781 atagagacgt cggatttttt tgatcgtttt tgcatcgatt tttggtcttc cgccgatttt
    24841 tcctttttta cgagcttcat ctaatccaac taatgtacgt tctttgatca atgcgcactc
    24901 catgtttgct aggttttcca ttaattggaa atagattttt cccatttcgc gcgtatcgat
    24961 tccttcatca agactaatca agtgcagccc gcgatctttg aataattgcg tgagttctgt
    25021 taattgccgc gtagatttgc ctaatcgatg aagttggcaa atgactagtg catcgccttg
    25081 ttgcatgtca gcgatcactg actccaaatg aacagcagta gaatcatttt gttccacttc
    25141 atatgtctca tggaaaattt cttgacaacc aaagtcagat aattgatcaa cctgagttgt
    25201 taaatcaacg tcatttatgg ttgtgcgtgc ataaccaata attttcatgg tgattccttt
    25261 ctagcagtga ttttctaact ggatataaca gtaaaaatgt agcataaagt acgtcaaaaa
    25321 gatagttttt tcgcaaattt tccgctgtct ttttttattg gatgatcaag cagtttttct
    25381 ttatttacga cggattgcgt caagaatctc aacgcctttt tctgagccga caactacttt
    25441 agaaaccatg tttaggaaaa gcccatgttc tactacccca acaagttcat ctaaataggt
    25501 agctaagctt tctggctgtt cgatgacttc tagatgcaga tcaatgatgt aatgaccacc
    25561 atctgtggtt aagacttctc cgttttcgtc tgtacgcaag acgggttgga atcttttttc
    25621 ttcaaaaata tgaagtagct gttgggagcc ataagggatc acttcaactg ggagtgggaa
    25681 cttcccaagt ttatcgacta atttagaaga atcaacgatc caaatcgttt cttttgagta
    25741 cgtagcgact attttctcga aaagcaaagc agcgccgccg cctttgatcc cttgaaaatc
    25801 agcactgatt tcatcagcac cgtctattgt caaatcgact acggggactt catcaatact
    25861 ctttaacggt attcctaatt tttccgcttg ttcttttgtc gcatttgaag tagtaactcc
    25921 tgtgatacgt aaaccttctt cacgcatacg gcgaccaatc tcttctacca tataataggc
    25981 ggttgaaccg gtcccgagac ctacgatcat cccgtccttt acgaatttcg cggcttcaat
    26041 gccagctaat tgttttaaat tcatctttgc gtccaccttt ttttagtttg agcatcgtgc
    26101 tttcctcact attttagcgt gatttacggt aaaaagatac cattcttttt tattccaata
    26161 aagctttttc aaaaaaaatt gcatctcttg ttgacatgtt ttttcattcg tgatattcta
    26221 acaaaggtgc tttatctaca ggtttctgtg aagaaacgtg ctgactgttt atcaaagcat
    26281 atttgataag gatgcagaca ttgcatttat tttttatcac aaaaaaagaa ccacctggat
    26341 gtgtggaact agacgcaaat cgtgggaagg aggaaacaag gaatgcctac aattaaccaa
    26401 ttagtacgta aacctcgtaa atcaaaggtg gaaaaatcta attcacctgc tttgaacaaa
    26461 ggatataaca gctttaagaa aactcaaact aacgtaaact cacctcaaaa acgtggggta
    26521 gcaactcgtg tgggtacaat gacacctaaa aaaccgaact cagctttacg taaatatgca
    26581 cgtgttcgtt tgtcaaactt aattgaagtt actgcttata tcccagggat tggtcataac
    26641 ttacaagaac acagtgttgt attattacgc ggtggtcgtg taaaagactt accaggggta
    26701 cgttaccata tcgttcgcgg tgctttagat actgctggtg ttaacgaccg taaacaaagc
    26761 cgttctaaat acggaactaa aaaacctaaa gcttaatttt aattattaaa caaatgaaac
    26821 ttgcttctac tatatagaag taattactat gaacaatatt tcggaaggag gagttacgga
    26881 tgccacgtaa aggtcctgtt gcaaaacgtg atgttttacc agatcctatt tataactcaa
    26941 aattagtaac tcgcttgatc aaccgtgtaa tggttgacgg aaaacgcggg attgcagcta
    27001 acattatcta taatgccttt gacttgatca aagaatctac aggtaacgat ccattagaag
    27061 tgtttgaaca agcaatgaaa aacgttcaac ctgttcttga agttaaagca cgtcgtgttg
    27121 ggggttcaaa ctaccaagta ccagttgaag ttcgccctga acgccgcgtt actctaggtc
    27181 ttcgttgggt agtaaactac gctcgcttgc gcggtgaaca cacaatggaa gaacgcttag
    27241 caaaagaaat catggatgct gcaaacaaca caggtgcttc tgttaaaaaa cgtgaagaca
    27301 ctcataaaat ggctgatgcc aaccgtgcgt ttgctcacta tcgctggtaa gattctctct
    27361 gtttggtcgg cttttataag tcgacctcag atagtgtcct tatttttagc aactagatag
    27421 taaagagagg agaaacaagg agaatgacca gagaattttc tttacaaaac actcgtaata
    27481 tcggtatcat ggcccacatc gatgctggta aaacgactgc tactgaacgt atcttgtact
    27541 atactggtaa aatccataaa attggtgaaa ctcatgaagg agcttcacaa atggactgga
    27601 tggaacaaga acaagaacgt ggtattacga tcacttctgc tgctactaca gcacaatgga
    27661 agggtcaccg aatcaacatc atcgacacac caggacacgt agacttcaca gttgaagttg
    27721 aacgttcatt gcgtgtactt gatggtgctg taactgttct tgatgcacaa tcaggtgttg
    27781 aacctcaaac tgaaacagtt tggcgtcaag caacaactta tggtgtacct cgtatcgtat
    27841 ttgcaaacaa aatggacaag atcggtgctg acttcttata ttcagtatca actttacatg
    27901 accgtttgca agcaaacgct cacccaatcc aattaccaat tggtgcggaa gacgacttca
    27961 caggaattat cgaccttgta acaatgaagg ctgaaatgta tacaaacgat cttggaacag
    28021 agatcgaaga aacagaaatt cctgaagaat accgcgaatt agctgaagaa tggcgcgaaa
    28081 aattggttga agctgtagct gaaactgatg aagaacttac tttgaaatac ttagaaggtg
    28141 aagaaatcac tgaagctgag ttaaaagaag gtatccgccg cgcaacagtt aacgtagaat
    28201 tctacccagt actatgtggt tcagcattta agaacaaagg ggttcaatta ctattggacg
    28261 ctgttcttga ttacttgcca tcaccgttag atatcccagc tatcaaaggg attgacccta
    28321 aaactgatga agaagtagaa cgtcctgcag acgacagcgc tcctttctca gctttagcat
    28381 ttaaagttat gactgaccca ttcgtaggtc gtttaacttt cttccgtgtg tactctggtg
    28441 ttttacaatc aggttcatac gtacaaaacg caacaaaagg caaacgtgaa cgtgttggtc
    28501 gtatcctaca gatgcatgcc aactctcgtt cagaaatctc tgaagtttac gctggagata
    28561 tcgctgctgc tgttggtttg aaagacacaa ctactgggga cacactatgt gatgaaaaga
    28621 gtctagttat tcttgaatcc atggaattcc cagaaccagt tatccaagtc gctattgaac
    28681 ctaaatcaaa agctgaccaa gataaaatgg gtgtggcttt acaaaaacta tctgaagaag
    28741 atcctacttt ccgtgctgaa acaaacgtgg aaacaggcga aacaatcatc gctggtatgg
    28801 gtgaacttca cttagatatc atcgttgacc gtatgcgtcg tgaattcaaa gttgaagcta
    28861 acgtaggtgc gcctcaagta tcttaccgtg aaactttccg tgctggcact caagccgaag
    28921 gtaagtttgt acgtcagtct ggtggtaaag gtcaatacgg tcacgtatgg attgaattta
    28981 caccaaatga agaaggtgct ggtttcgaat ttgaaaatgc gatcgtcggt ggggttgttc
    29041 ctcgtgaata cattccagct gttgaaactg gtttgaaaga tgctatggaa aatggtgtct
    29101 tagctggcta tccattagta gatatcaaag ctaaacttta cgatggttca taccatgatg
    29161 tcgattcaaa tgaaactgcc ttccgtgttg ctgcttctat ggcattacgt gcagcagcta
    29221 agaaagctaa tccagtaatc cttgaaccaa tcatggctgt agaagttgtt atccctgaag
    29281 attatttagg tgatgttatg ggtcacgtaa ctgctcgtcg tggacgtgtt gaaggtatgg
    29341 aagctcgcgc tggcggccaa caagttgttc gtgcgatggt tccacttgct gaaatgtttg
    29401 gttatgctac aactcttcgt tctgctactc aaggtcgtgg tacatttaca atgacatttg
    29461 accactacga agatgtacca aaatcagtac aagaagaaat cattaagaaa aacggcggaa
    29521 aagctgaata atttcttaaa accggatagt cctgcaaaga gattatccaa agagactata
    29581 tttttaatat agtttcgtgt aaaataatta tcgatgatat gggcatgtgg tgtaccttgt
    29641 gtacatcata tacctatcag acaaataaaa aatatattgt atttttagga ggacatttta
    29701 aaatggcaaa agaaaaattt gaccgttcta aaccacacgt taacattggt actatcggac
    29761 acgttgacca tggtaaaact acattaacag ctgcaatcac aactgtacta tctaagaaaa
    29821 acggcggcca agctatggct tacgatcaaa tcgatggtgc tccagaagaa cgcgaacgcg
    29881 gaatcacaat ctcaacagct cacgttgagt atgaaacaga tacacgccac tacgctcacg
    29941 ttgactgccc aggacacgcg gattacgtta aaaacatgat cactggtgct gctcaaatgg
    30001 acggagctat cttggtagtt tctgctgctg acggcccaat gcctcaaact cgtgaacaca
    30061 tcctattgtc tcgtcaagtt ggtgttcctt acatcgttgt attcttgaac aaagtagaca
    30121 tggttgatga cgaagaatta ctagaattag ttgaaatgga agttcgtgac ctattaacag
    30181 aatacgaatt ccctggtgac gatgttcctg tagttgctgg atcagctttg aaagctctag
    30241 aaggcgacgc ttcatacgaa gaaaaaattc ttgaattaat ggctgcagtt gacgaataca
    30301 tcccaactcc agaacgtgac aacgacaaac cattcatgat gccagttgaa gacgtgttct
    30361 caattactgg acgtggtact gttgctacag gtcgtgttga acgtggacaa gttcgcgttg
    30421 gtgacgaagt tgaagttgtt ggtattgctg aagaaacttc aaaaacaaca gttactggtg
    30481 ttgaaatgtt ccgtaaattg ttagactacg ctgaagctgg agacaacatt ggtgctttac
    30541 tacgtggtgt tgcacgtgaa gacatccaac gtggacaagt tttagctaaa ccaggtacaa
    30601 tcacacctca tacaaaattc tctgcagaag tatacgtgtt gacaaaagaa gaaggtggac
    30661 gtcatactcc attcttcact aactaccgtc cacaattcta cttccgtaca actgacgtaa
    30721 caggtgttgt tgaattacca gaaggaactg aaatggttat gcctggcgac aacgtaacaa
    30781 tggaagttga attaatccac ccaatcgcta tcgaaaacgg tactaaattc tcaatccgtg
    30841 aaggcggacg tacagttggt gccggtgtcg ttacagaaat caaagcttaa ttcacttaag
    30901 ttttaaagta aagcaacatt tattcggacg taatcgctcg gaacgaaggt cttaggatct
    30961 ttgttccgag cttttttatt tattgcagga tcaggaaaaa agacaggagt attataaata
    31021 gaagaaacac gaaataaaag agtcagtatt ttctaaatga aactttatga aaacaaaatg
    31081 ttttttacaa gaaaaagcct tgctttgtga gtttatatat attataatga caaaggtgcg
    31141 tttactttag tgaattgcac agacgtaatc agaatgattt cgtcggctaa gaaacgagag
    31201 gttgcgacac gcccggacgc tttgccacga acgagcgtga cggaaatttt cgtggagcta
    31261 tgtctacttt tcaaaatagg cgaaggaggg aacaagatgg caaaacaaaa aattcgtatc
    31321 cgtttaaaag cgtatgaaca ccgtatttta gatcaatcag cggataaaat cgtggaaact
    31381 gcaaaaagaa ctggagctag cgtgtctggt ccaattccat taccaactga acgcagtctt
    31441 tacacaatca tccgtgcgac tcataaatac aaagattcac gcgaacaatt cgaaatgcgt
    31501 acacacaaac gtcttatcga cattgtgaac ccaacaccaa aaactgttga tgctttgatg
    31561 aagctagact taccatctgg tgtaaacatc gaaatcaaat tataaaacta aaacaaaaat
    31621 aatggaggtg tactcatgac caaaggaatc ttagggaaaa aagtgggaat gacacaaatc
    31681 ttcactgaat ctggtgaatt aattccagta actgttgtag aagctactcc aaacgtagta
    31741 ctacaagtga aaacaatgga aacggatggc tacgaagcta ttcaagttgg ttaccaagat
    31801 atgcgtgaag ttttatcaaa caaacctgcg aaaggtcatg ttgcaaaagc aaacacggct
    31861 cctaagcgct tcattcgtga attcaaaaat gttgagctag gagaatatga agtaggaaaa
    31921 gaaattacag tagatgtttt ccaagcagga gacattattg atgtaacagg tactacgaaa
    31981 ggtaaaggat tccaaggggt tatcaaacgc cacggacaaa gccgcggacc aatggctcac
    32041 ggttctcgtt accatcgtcg tcctgggtca atgggtccag ttgcacctaa ccgtgtattt
    32101 aaaaacaaac gtcttgctgg ccgtatgggt ggcaaccgcg taactatcca aaacttggaa
    32161 gttgtacgtg tcgatgcaga aagaaatgtt atcttgatca aaggtaatgt tcctggagct
    32221 aaaaaatctt taattactat caaatcagct gtgaaagcta aataattgta ggaagaaagg
    32281 aggaactaag gaatgccgaa tgtagcatta ttcaaacaag atggaagcca aaacggtgaa
    32341 atcacactta acgaagaaat cttcggaatt gaacctaatg aaagtgttgt ttacgatgca
    32401 atcgtaatgc aacgtgcgtc attaagacaa ggaacacacg cggttaaaaa ccgtagcgct
    32461 gttcgcggcg gcggacgtaa accatggcgt caaaaaggaa caggtcgtgc acgtcaagga
    32521 tctatccgct caccacaatg gcgtggaggt ggcgtagtct ttggaccaac accacgttct
    32581 tacagctaca aacttcctaa aaaagttcgt cgtttagcaa tgaaatctgt attgtcagaa
    32641 aaagttgctg aaaacaactt ggtagcaatc gaaggcttga acttcgacgc accaaaaaca
    32701 aaagaattca aacaagttct tgctaactta tctatcgact ctaaagtatt ggttgttcta
    32761 gaaaaaggta acgactttgc tgctttatca gcacgtaact taccaaacgt ttctgtagta
    32821 acttctgata atgtgagtgt gctagacgtt gtatcaaata caaaagtgtt agcaacacaa
    32881 actgctctta ctcaaattga ggaggtgctt gcataatgaa cttactagac gtaatcaaac
    32941 gcccagtgat cactgaaaaa tcaatgcttg ccatggatga caagaaatac acttttgaag
    33001 tggacactcg cgcaaacaaa actttagtaa aacaagcggt agaagctgct tttgacgtta
    33061 aagtcaaaaa cgtgaacatc gtgaacgtac gtgcgaaatt caaacgtatg ggcaaatatg
    33121 caggatatac aaaaaaacgt cgcaaagcga tcgttacatt gactgaagat tcaaaagaaa
    33181 tccaattatt cgaagctgct gaataagcac taatagataa ctcattaaat taggagggaa
    33241 aaacgtggcg attaaaaagt acaaacctac ctcaaatggt cgtcgtaaca tgacaggttc
    33301 tgattttgct gaaatcacaa catcaacacc tgaaaaatca ttgttacaac cattgaaaaa
    33361 ccatgctgga cgtaacaaca acggccgcat cactgtacgt catcaaggtg gcggacacaa
    33421 acgccaatat cgcgtgatcg acttcaaacg taacaaagat aacgttgttg caactgttca
    33481 aacgatcgaa tatgatccaa accgttcagc taacatcgcg ttagtacact atgaagatgg
    33541 agtgaaagct tacatcttag cacctaaagg actagaagtg ggtatgaaac ttgtttcagg
    33601 tccagaagca gatatcaaag tcggaaatgc tcttccatta gaaaacattc cagttggtac
    33661 tgttatccac aacattgaaa tgaaacctgg taaaggtgga caattgatcc gttctgctgg
    33721 tacaagtgct caagtacttg gtaaagaagg caaatacgta ttgatccgct tgaactctgg
    33781 tgaagttcgt atgatcttag ctgcatgccg tgctacaatc ggttctgtag gtaacgaaca
    33841 acacgaatta atcaacatcg gtaaagctgg acgctctcgt tggatgcgta aacgcccaac
    33901 tgtacgtggt agcgtaatga accctaatga tcacccacac ggtggtggtg aaggtaaagc
    33961 tcctatcgga cgtaaagcac cagtttctcc ttggggtcaa ccagctcttg gttacaaaac
    34021 tcgtaacaaa aaagctaaat cagacaaact tattgttcgt cgtcgcaaaa ataaataatt
    34081 actttgacca tgtgtcgcac attttgagag gaggttcacc atgggtcgta gtttaaagaa
    34141 aggacctttt gtcgatgagc atttaatgaa aaaagttgaa gctcaagcag gggttgaaaa
    34201 gaaaaaagtt atcaaaactt ggtcacgccg ttcaacagtt ttcccaagtt ttgttggata
    34261 taccatcgca gtttatgatg gacgtaaaca tgtaccagtt tacatccaag aagacatggt
    34321 aggacacaaa ttaggtgaat ttgcacctac aagaacttat cgtggacatg ctgctgacga
    34381 taagaaaacg aaacgctaat ttgaggggag gataaatcca aatggcagaa caaatcacat
    34441 cagctaaagc aactgcaaaa acagttcgca cttcacctcg aaaagcccgt ttagtaattg
    34501 accttatcag aggtaaaagt gtcgcagatg caatttcaat cttgaaattc acaccaaaca
    34561 aatctgctgg aatcattgaa aaagtattga tgtcagcagt tgcgaatgca gaaaataact
    34621 ttgacttaga tgttgaaaac ttggtagtaa gcgaagcttt tgttaacgaa ggacctacaa
    34681 tgaaacgttt ccgtcctcgt gcaaaaggat cagcttctcc aatcaacaaa cgtacaagtc
    34741 atatcacggt agtcgtatca gaaaaataag gagggataat cagtgggtca aaaagtacat
    34801 ccaattggaa tgcgtgtagg catcatccgc gactgggatg ctaaatggta tgctgaaaaa
    34861 gagtatgctg agttcttaca cgaagattta agaatccgta aatttatttc aactaaactt
    34921 gctgatgctg ctgtatcaac agttgaaatc gaacgcgcaa caggtcgcgt aaacatttca
    34981 attcacacag ctaaaccagg tatggttatt ggtaaaggcg gttctgaagt cgaaagccta
    35041 agaaaagaat taaacaaatt aactggtaaa agaatccata tcaatatcgt ggaaatcaaa
    35101 aaaccagatc tagatgcaaa attagtaggt gaaggaatcg cacgtcaatt agaaaaccgt
    35161 gttgctttcc gtcgcgctca aaaacaagcc atccaacgct caatgcgtgc tggcgctcaa
    35221 gggatcaaaa ctcaagtatc tggtcgtcta aacggagcag atatcgctcg ttcagaagga
    35281 tactcagaag gaactgttcc tcttcatact ttacgtgcgg acattgatta cgcatgggaa
    35341 gaagcagata caacatacgg aaaactagga gttaaagtgt ggatctatcg tggagaaatt
    35401 cttccaacta aaaaaaacac tgagaaagga gggaaataat catgttagta cctaaacgtg
    35461 taaaacaccg tcgtgaattc cgcggaaaaa tgcgcgggga agctaaaggc ggaaaagaag
    35521 tagcattcgg tgaatacggt ttgcaagctg ttgattcaca ttggatcaca aaccgccaaa
    35581 tcgaagctgc tcgtatcgca atgactcgtt acatgaaacg tggtgggaaa gtatggatta
    35641 aaattttccc tcacaaatct tatactgcca aagcaattgg ggtacgtatg ggttctggta
    35701 aaggggcacc tgaaggatgg gttgcaccag taaaacgtgg taaaatcatg tttgaaatcg
    35761 caggcgttcc tgaagaagta gctcgtgaag cgttacgtct agcttctcac aaattaccaa
    35821 tgaaaactaa gatcgtaaaa cgtgaggaaa tgggtggtga atcgaatgaa ggttaaagaa
    35881 atcagagaat taaccactgc cgaaatgctt gatcaagaaa aacaattaaa agaagaattg
    35941 tttaatctta gattccaatt agcaacaggt caattagaaa acactgcacg tattaaagaa
    36001 gtacgtaaat cgattgcacg catcaaaact gtgttgcgtg aacaagctaa gtaattatgg
    36061 aaggaggcca ttaagcgtat gactgaagga agaaatcaac gcaaagttta tcaaggtcgc
    36121 gtggtttcag acaaaatgga taaaacaatt accgttgctg tcgaaacaaa gaaaaaccac
    36181 cctatctatg gcaaacgcat gaactattct aagaaataca aagtgcatga tgaaaacaac
    36241 acagcaaaag ttggcgacat cgtgagaatt atggaaactc gtccattatc agctacaaaa
    36301 cgtttccgtt tgttggaagt agtcgaagaa gcagttatta tctaataaca cgagattttc
    36361 ctatatagat tgaatgcaaa atctgaaagg aggatacaca acgtgatcca agcagaaagt
    36421 cgtttaaaag tcgctgataa ctcaggcgca cgtgaaattt tgacgatcaa agtccttggt
    36481 ggatctggtc gtaaaactgc taacatcggt gatgtgatcg ttgctacggt taaacaagca
    36541 acgccaggtg gggttgtcaa aaaaggtgac gtcgttaaag ccgttatcgt tcgaacaaaa
    36601 tcaggagctc gtcgtacaga cggttcatat attaaatttg atgaaaatgc tgcagtgatt
    36661 attcgtgatg ataaaagccc tcgtggaaca cgtatctttg ggccagttgc acgtgaacta
    36721 cgtgaaaaca acttcatgaa gatcgtttca ctagcaccag aagttttata atcttgagac
    36781 acttatcaaa ggaggtgcga aacagttatg tttgttaaaa aaggcgataa agttaaagtt
    36841 atcactggaa aagacaaaaa caaagaaggc gttgtactag cagcgttccc gaaaaaagat
    36901 aaagttattg tcgaaggtgt aaatgtcgtt aaaaaacacc aaaaaccttc tcaagctgct
    36961 cctcaaggtg gaattgttga gatggaagcg ccaattcatg tttctaacgt gatggtggtt
    37021 gactctactg gtgtagctgg ccgagttggc tacaaagaag tagacggcaa aaaagtccgt
    37081 gtttctaaaa aaaccggtga agttttagat aaataaaagt ttaaggaagg agggtcttac
    37141 tgaatgaacc gcctaaaaga aaaatatctt aaagaagtaa ctccatcatt gatggaaaaa
    37201 tttaactata gctctgttat gcaaacacct aaagttgaaa aaatcgtcat caacatgggt
    37261 gttggtgatg cggtatcaaa cgctaaaaac ttagataaag cagttgaaga attaactttg
    37321 atcactggtc aaaaaccaat gattacaaaa gctaaaaaat caatcgctgg attccgttta
    37381 cgtgaaggaa tgccaattgg tgcaaaagtt acattgcgcg gagaaagaat gtacgaattc
    37441 ttagacaaat tggtttctgt ttcactacca cgtgtacgtg acttccatgg tgtaagtaaa
    37501 aaagcctttg acggtcgtgg aaactatact ttaggtatta aagaacaatt gatcttccca
    37561 gaagtagatt atgatttagt agataaagta cgtggtatgg acatcgttat tgtaacaaca
    37621 gcaaactctg atgaagaatc tcgtgagttg ttgacacaat taggcatgcc attccaaaaa
    37681 taattaaagg aggcgaacta cgtggctaaa aaatcaatga ttgctaaaaa caaacgtcct
    37741 gcaaaatttt caacacaagc ttatactcgt tgcgaacgtt gcggacgtcc acattcagtt
    37801 tatcgtaagt tccatctttg ccgtatttgc ttccgcgaac ttgcctataa aggtcaaatt
    37861 cccggcgtga agaaagctag ctggtaaaaa gtaaattcgc ataagaagga ggtaaaagat
    37921 caatggtcat gacagatcca attgcagatt ttctaactcg tatccgtaac gcaaacatgg
    37981 ttaaacatga gtctttagaa gtacctgcat caaaaattaa acgtgacatc gctgaaatct
    38041 tgaaacgtga aggtttcgtt cgtgatgttg aatacatcga agatgacaaa caaggcgtga
    38101 tccgtgtttt cctaaaattt ggtaaaaacg gcgaacgtgt tatcacaaac ttaaaacgta
    38161 tctctaaacc aggtttgcgt gcttatgtca aagctgacga agtaccaaaa gtattgaacg
    38221 gtttaggtat cgcaatcatt tcgacttctg aaggtgttgt cactgataaa gaagctcgtg
    38281 aaaaaaatat cggcggcgaa gttatcgctt acgtatggta atcaagtaga atctacaagg
    38341 aggtgtcttt aagtgagccg tatcggaaat aaagtcgttg ttatccctga aggagtaaca
    38401 gttactcaag acggaaacaa cgttacagtt aaaggaccaa aaggtgaatt gactcgtact
    38461 ttttcagcag atatcaaaat gaatatcgaa ggaaacgaag taactttcac tcgtccaaac
    38521 gacagtaaag aaatgaaaac aattcatgga acaactcgtg cgaacttcaa caacatggtt
    38581 gtaggtgtca gcgaaggttt ccaaaaagcg ttagaactaa tcggggttgg gtaccgtgca
    38641 caattacaag gatcaaaact tgtattgaac gttggttact cacatccagt agaaatcaca
    38701 ccaccagctg gagtaactgt tgaagtacca gctaacacac aagtaattgt taaaggtgcg
    38761 aacaaagaag aagttggcga attagctgca aacattcgtg gaactcgtcc tccagaacct
    38821 tataaaggta aaggtattcg ttatgttggc gaatatgtac gccgtaaaga aggtaaaact
    38881 ggtaaataat cgtttagaaa aattgcatag aagccagcag caggaaaaag gcatttggct
    38941 gaagtttacc ttcaaaaaaa tacattttta cttgtgccgc agcttctatt tttcgaaacg
    39001 tatttactgc ttgaaatagt agtacaataa aaataaagag gtgacaattg tgattacaaa
    39061 accagataag aacaaaacac gtcaaaagag acatcgtcgt gtacgtaaca atatctctgg
    39121 tactgctgag cgcccacgct tgaacgtttt tcgttctaac aaaaacatct acgctcaaat
    39181 tattgatgac gtagcgggtg taacgctagc aagtgcctct accttggata aagaaatttc
    39241 aggtggaaca aaaacagaag cagcacaagc tgtcggtaaa ctagttgctg aacgtgcagc
    39301 tgaaaaaggc attaaagtag tagtctttga ccgtggtgga tacctttacc atggccgtgt
    39361 gcaagcttta gctgaagctg ctcgcgaaaa tggactagaa ttttagaaga aggaggaata
    39421 ccattcatgg tttatatcga tccaaaacat ttggaattag aagaccgcgt tgttgcaatt
    39481 aaccgtgtaa caaaagttgt taaaggtgga cgtcgtctac gttttgctgc tttagttgtt
    39541 gtcggtgaca aaaacggaca cgtagggttt ggtacaggta aagctcaaga agttcctgaa
    39601 gcaatccgta aagcaattga agatgcgaag aaaaacttag ttgaagtacc tatggttggt
    39661 tcaacaatcc cacacgaagt aatcggtgct tttagtggtg gtagaatcct aatgaaacct
    39721 gctgtagaag gttctggggt tgctgctggt ggaccagttc gtgccgtatt agaattagct
    39781 ggggtagcag atatcacttc taaatcttta ggctcaaata caccaatcaa cgttgttcgc
    39841 gcaacagttg aaggtttgaa acaattgaaa cgtgcagaag aagttgcaga acttcgcggc
    39901 aaatcagttg aagaattaat cggataagga ggacaacaat aatggctgaa ttaaaagtta
    39961 ctttaaaacg cagtattatc ggacgtcctc aaaaccaacg cgatacagtt aaagcgttag
    40021 gtcttacaaa gattaacagt tcagtggtta agccttctaa tgaagcaatt aaaggcatga
    40081 tcaatactgt ttctcaccta gtggacgttg aagaaattta atttagaaaa atcataacta
    40141 gaacattaag gaggtgccaa acctatgaaa cttcatgaat taaaacctgc tgaaggttca
    40201 cgccaagtac gtaaccgtgt tggtcgtggt acttcatctg gtaacggaaa aactgccgga
    40261 cgcggacaaa aaggacaaaa agctcgttca ggcggcggtg tgcgtttagg atttgaaggg
    40321 ggacaaacac cattgttccg tcgtttacca aaacgaggat tcacaaacgt gaaccgtaaa
    40381 gactatgcag tcattaatct tgatgtattg aaccgctttg aagacggagc tgaagtaact
    40441 cctgttgctt tagttgaagc tggaatcgtg aaaaacgaaa aagctggaat caaagtatta
    40501 gctaatgggg aactaaacaa gaaattaact gtgaaagcag caaaattctc taaagcagct
    40561 caagaagcaa ttgaagcggc tggtggatca atcgaggtga tctaatgttt agactattaa
    40621 aagatgcttt taaagtaaaa gacattagat cgaaaatcct atttactgta tttgtgttgt
    40681 ttgtatttcg cctaggtgca catattactg taccaggcgt aaatgctgct tcattgcaaa
    40741 acctttcttc tttgccattt ttcaacatgt tgaacttggt aagtggtagt gcgatgcaaa
    40801 acttttccat tttctcaatg ggggtttcac catacattac tgcttctatc gtcattcagc
    40861 ttcttcaaat ggacatcgtg cctcgatttg ttgaatggtc gaaacaaggg gaagttggtc
    40921 gtaaaaaact gaatcaagcg actcgatatc tgacattagt attggcattt atccaatctg
    40981 tcggtatcac tgctggattc aatcaatacg ctcaattagg tttcgtgaat aatcctaacg
    41041 tagcaactta cgtaacgatc ggtttgattc taacagccgg tacgatgttt gttacttggc
    41101 taggagaaca gatcacagaa aaaggtatcg gaaatggcgt atcaatgatc atttttgcag
    41161 gtatcatttc tagattgcct gaaagtatca gagaaattta tgaagattac tttataaata
    41221 ttgatccttc agacatatgg aaatctgcta tttttgtggc cattttacta gtagcggtct
    41281 tgttgatcgt gacattcgta acatttttcc aacaagctga acgcaagatc ccgatccaat
    41341 atacgaaacg cgtagctggc gcgcctacaa gcagctatct gccgttgaaa gtaaatgcag
    41401 ctggagttat tccagttatc tttgctagtt cgtttattgc tacgccaaat gctgttttac
    41461 aagcattgag cggtagattc ggttctgaaa actggtacaa agtgatgatg gagatcttta
    41521 actataatac agcacctggt gctacgattt atacgattct gatcgttgcc ttcactttct
    41581 tctacgcctt tgttcaagta aaccctgaga aattagcgga aaacttgcaa aagcaaggaa
    41641 gttatatacc aagcgtacgc cctggtaagg ggactgaaga gtatgtctca agattactga
    41701 tgcgtttaag tacagttggt gcagtcttcc ttggtttagt ggcattgctt ccaatcattg
    41761 ctcaaatggt ttgggatctt ccacaatcaa tcggattagg cggtacaagc ttactgatcg
    41821 ttatcggtgt agctttagaa actgcgaaac agttagaagg cttaatgctg aaacgtaaat
    41881 atgttggatt cattgagtaa gaaagcgtgt tgaggtttcc cctcaacaca cgttctcaca
    41941 catttattag gagggaaaac aatgaacctc attttaatgg ggctgccagg cgcaggtaaa
    42001 ggaacacaag ctgaaaaaat cattgatgct tatggtattc cgcacatctc aacaggagat
    42061 atgttccgcg cagcgatgca aaacgaaaca gctcttggcc tggaagcaaa gtcttatatg
    42121 gataaaggtg cattagttcc tgatgaagta acaaatggaa tcgtgaaaga gcgactagct
    42181 gaaccagata cagagaaagg cttcttatta gatggctttc cacgtacgct agatcaagca
    42241 aaagctctgg acgcaatgct aaaagatttg aataaaaaaa ttgatgctgt catcgatatc
    42301 catgttggtg aagaaatctt ggtcgaacgt ctagccggcc gatttatctg cagcaattgt
    42361 ggagcaactt accataaaat tttcaaccct acaaaagttg aagacacatg tgatcgttgc
    42421 ggtgggcatg aattctatca aagagaagat gataaacctg agacggttaa aaatcgtctg
    42481 gctatcaaca tcaaaaatag tgaaccaatc ttggcttatt ataaagaaca aggtttgcta
    42541 aacactattg atggtgctcg tgaaatcgat gctgtatttg cagatgtaca aaaaatcatt
    42601 gaaaaatagc acgattgccc gtagccgact tgcattatgc agttactctt gtcaagttca
    42661 ataaattatg atagaatatg tcagtccgac ttctagagaa tcctctagat gatccatttt
    42721 gagaattttg aggtgggaac tgcagtttcc gccattttat cgtgtgaaaa tgcgaaacaa
    42781 gtacaaggag gtactgtgcg tggcaaaaga agatatgatt gaagtcgaag gtacagtcgt
    42841 cgaaactttg ccgaatgcaa tgtttaaagt tgaactagaa aacggacacc aagttcttgc
    42901 tactgtttca ggtaaaattc gtatgcatta catccgtatc ttacctggtg acaaagtaac
    42961 ggttgaattg tctccatacg atcttaaccg tggccgtatt acttatcgct ttaaataatt
    43021 gtactccgta aaactacagg aggtattatc atgaaagtaa gaccatcagt aaaaccaatg
    43081 tgcgaacatt gtaaagtaat tcgtcgtaaa ggacgcgtta tggtgatttg cccagcaaat
    43141 ccaaaacata aacaacgtca aggataattg gaggtgctat aaatatggct cgtattgcag
    43201 gagtagatat tcctcgtgat aaacgtgtag tagtttcact tacttatatc tatggtattg
    43261 gtaacactac tgctaaaaag atcttagctg atgctggtgt atctgaagat gttcgcgttc
    43321 gtgaattaac gaatgaacaa acagatgcta tccgtgcaga agtagataaa ttaaaagttg
    43381 aaggggatct tcgtcgtgaa gtgaacttga acatcaaacg tttgatggaa atcggttctt
    43441 accgtggaat ccgtcatcgc cgtggattgc ctgttcgtgg acaaaacacg aaaaacaatg
    43501 cacgtactcg taaaggccca gctcgcgcta tcgctggcaa gaaaaaataa ttcttaagtg
    43561 aaggaggtta aaacttcatg gcagcaaaaa aagtgaatcg taaacgccgt gtgaagaaga
    43621 atatagaagc aggtattgca catatccatt ctacattcaa taacactatc atcatgatca
    43681 ctgatactca cggaaatgca ttagcgtggt catcagctgg ttcattaggt ttcaaaggaa
    43741 gcaaaaaatc aactcctttt gccgctcaaa tggcagcaga aactgctaca aaagcagcaa
    43801 tggaacacgg attaaagact gttgaagtaa cagttaaagg acctggttct ggacgtgaag
    43861 cagcaattcg ttcattacaa gctacaggtt tagaagtgac tgcaattcgt gacgtgactc
    43921 cagttcctca taatggtgcc cgccctccaa aacgccgtcg tgtttaatga gtgccgctca
    43981 ttttgagttt tatcagtaac gtcattgaac aagacacttt tcgttttgaa aggggtaaag
    44041 ataagaatga ttgagttcga aaaaccaaga atcgcaaaaa ttgatgaaga aaaagattat
    44101 ggcaagttca tcgttgaacc tcttgaaaga gggtatggga ctactttagg gaattcccta
    44161 cgtcgtattt tattatcttc tttgccaggt gctgccatca ctaatattca aatcgatggt
    44221 gtactgcatg aattctctac catcaaaggt gttagagaag acgtcactca aatcatcttg
    44281 aacattaaag gcttagcgct gaaaatgtat ggccaagaag aaaaaaccct tgaaatcgat
    44341 attaccggac ctgctacagt aactgctggc gatattatcg ttgatagtga tgtagaaatt
    44401 cttaacaaag atatgtacat ctgtagtgtc tctgaaggag ctacgttcca tgctcgctta
    44461 acagtgaaac ctggacgtgg ttatgttcaa gcagatgaaa ataaaaaaga agatatgcca
    44521 attggcgttc ttccagtcga ttcaatctac acacctgttc gtcgtgtgaa ctatcaagtt
    44581 gagaacacac gtgttggaca ccgtgaagat tttgataaat tgacgatgga gatttggaca
    44641 gatggttcaa ttgaaccgtt ggaagcaatg agtttgtctg cgaaaatcat gactgaacat
    44701 ttggatattt ttgtgaactt aactgatgaa gcaaaaaatg ctgaaatcat ggtcgaaaaa
    44761 gaagaaacac aaaaagaaaa aatgttggaa atgacgatcg aagagttaga cttgtctgtt
    44821 cgctcttaca attgtttgaa acgtgcagga atcaatactg tacaagaact tacaaataaa
    44881 tctgagcctg aaatgatcaa agtccgtaac ttaggacgta aatcattaga agaagttaaa
    44941 gcaaaattgc acgacttagg tttaggttta cgtaaagaag attaaaacct tttacgaagg
    45001 agggaaacca acgtgagtta tcgtaaacta ggacgcacat ctagccaacg taaagcgatg
    45061 ttgcgtgatt taacaactga tttattaatc aacgaacgta ttgtgactac tgaagctcgt
    45121 gcgaaagaag ttcgctcaac tgcagaaaaa atgatcactt taggtaaacg cggagatttg
    45181 catgcacgtc gtcaagctgc ggctttcgta cgtaatgaag ttgccagcgt gcgtgaagaa
    45241 aatgaggaca tcgtcattga atcagcttta caaaaactgt tcaacgatat tgcacctcgt
    45301 tacgcagaac gtcaaggcgg atacacacgc attttgaaga cagaaccaag acgcggtgat
    45361 ggtgcaccaa tggttgtctt agaacttgtc taaaatcaca ctaataacat cactttatag
    45421 atgattcttt tagagtgtta tgatgttgga agatattttt ccgagtctag ctcagcgctg
    45481 ctcctcaagc gaatatcgct tggggagtaa gcactcatca taaagtgttt ttttatacct
    45541 tcaattacct gtcatgacag atatgtttga aggcataaaa aaacatttta agcgagaaat
    45601 aattgaaaat tttgtctttt tttgatagtg ttagtaggaa ctttaggatg aagaaggagt
    45661 aatcatggag ccaattattg aattagaaaa gataaattat aaataccagc cagatgatct
    45721 tcgccccgca ttgaaagatg tctcctttac aattgataaa ggtgagtgga tcgctattat
    45781 tggacacaat ggttcaggaa aatcgacact tgccaaaacg atcaatggat tgcttctgcc
    45841 agaatcaggg atcgtgaaag tgggaaatca aatattggat gaagaaaata tttggacgat
    45901 ccgacagatg gttggaatga tttttcaaaa tccagacaat cagtttgttg gttcgacagt
    45961 agaagatgac gttgcttttg gtcttgaaaa tcaagggatt cccagagaag aaatgctagt
    46021 gcgtgtgaaa gatgcacttg agaaagttag aatggctgag tttgcttcac gcgagcctgc
    46081 tcgtttatca ggagggcaaa aacaacgtgt tgccattgcc ggcgtggttg ccttacgacc
    46141 tgatatcatt attttagatg aagcaaccag tatgctagat ccagaaggtc gtgaagaagt
    46201 gatctctacg atcaagaaga tcaaagaaga aagtcaattg accgttatat ctatcactca
    46261 tgatattgat gaagcagcta atgccaatcg gatactagtg atgagacaag gcgaacttgt
    46321 ccgtgaaggt acaccaaaag aaattttttc tgctggtcct gaactgatcg acttaggtct
    46381 agatctacca tttcctgaaa aactgaagag cgcactgaaa gaacgtgggg ttgatgtgcc
    46441 cagtgaatat atgacagaag aaaggatggt ggattggtta tggacatccg ttttgaacaa
    46501 gtagacttca cttatcagcc gaatacacca tttgaacaaa gagccttatt tgacatcaat
    46561 atgacgatca aagaaaacag ttatactgca ttagtagggc ataccggaag cgggaaatca
    46621 accttacttc agcatttgaa tgcgcttgtt aagccaacaa gcggtacagt ccatattgga
    46681 gaacgagata ttcagccgga tacggataat aagaatttaa agcccatccg aaaaaaagtt
    46741 ggcatcgtct ttcagtttcc agaagcacag ctattcgaag aaacggtagc aaaagacatt
    46801 gctttcggtc ctaaaaactt tggtgtcagc gaagaagaag cactagtcct agcaaaagaa
    46861 acattagaac aagttgggct ggatgaaagc tatttggaac gttcgccatt tgaactttca
    46921 ggagggcaaa tgcgtagagt agcaatcgct ggtgtgcttg ccatgaggcc ggaagtactt
    46981 gtattggatg aaccaacggc aggacttgat ccccagggca gaaaagaaat gatggagatg
    47041 ttttggcgtc ttcataagga acagcagatc actattgtat tagttacgca tttaatggat
    47101 gatgtagcca attttgcaga ttatgtctat gtgttggaaa agggacgaat cgttaatagc
    47161 ggggagccgc aagaggtctt tcaaaacatt gaatggctaa aagaaaaaca actaggcgta
    47221 cctactgcca ccgagtttgc agaagaatta atggctaaag ggatgaactt tgctaccttg
    47281 cctttgacag ctgaagaatt agcagacgct atcgtccatt atgctggagg aaatgcccat
    47341 gatgaataaa ttgatatttg gtcgttatat gcctggagat tccttgatcc atcgattgga
    47401 tccccgagct aaattattag ccagttttta ttttatcgga atcatttttt tagcaaataa
    47461 ttgggaaacg taccttttgt tggcattttt cacattactt tctgtcttct tgtcaaaagt
    47521 agatttgaaa ttttttatcc gaggcattcg cccattgatc tggctaatcc tcttcactgt
    47581 agctttgcag gtcttgttta caagtggcgg agaaacttat tggagttggg gtgttttcca
    47641 tatcactgaa tttggtgtga tgaacggcct ctttattttc tgtcgattcg tgttgatcat
    47701 ttttatgtcg actctactca cgcttactac accgcctttg gaattatcgg atgcgattga
    47761 gtacttgctt cgtccattga aagccgtacg gttcccagtc cacgaaattt cattgatgct
    47821 gtcgattgct cttcgttttg tgcctacatt gatggacgaa acagaaaaga tcatgaacgc
    47881 tcagcgcgct cgcggtgttg attttggtga aggaaaccta gttcagaaaa tgaaagcagt
    47941 cattcctttg ctgattcctt tatttgtcag cagcttcaac cgtgcggaag atcttgcgac
    48001 tgctatggaa gcaagaggct acaaaggtgg ggaaggaaga acgaaatatc gtgtattgca
    48061 ttggcataat agagacacga tggttatcat tgcttttgta ttattaactg tgctactgat
    48121 ctttttaaga ggataaacgt tcagtgggcc gctatctatt cttttcttgc tgatctgttt
    48181 gcaagaaagg atgcaagcag tgtatgacaa gaaatattag ggtctgtggc agactaaggt
    48241 cacaggcctc tttcttttat ctgaaaagaa agaacgaaaa aattttatag aaaaatcatt
    48301 attccagata accttttagg aacaaaggag agaaaaacat ggtacgttac aaagcaatca
    48361 ttgcgtacga cggaacaaat tttaatggat tccaaaaaca gccaaatggg cgtactgttc
    48421 aagaagaagt agaaaaaaca ttacaaaaaa tggcaaatgg aaaagaaatc acggtctttg
    48481 gttcgggaag gacagatgcc ggagtacatg cgatcgggca agtaatccat tttgattatc
    48541 cagaggagcg tccgttagaa cgaatgcgtt tcgcgctaga tacccagtca ccagaggata
    48601 ttgctgtaag acaagtagaa attgtttcag aagacttcca cgcaagatat ttggtcaaag
    48661 aaaagacgta tcaatttcga gtggatatag ggaaaccacg cagtcctttt cgacgccatt
    48721 atgcaagtta ttttccttac ccacttgatt tggaaaaaat tcagcgggcg cttcctgatt
    48781 tattagggac tcacgatttc acctcttttt gtgcatcagg aagctcgata gaggataaaa
    48841 tacgtacgat ctacgaggct aagatggagg taaatgaaac aaaagacgaa ttgttgttta
    48901 catttagggg aaatggcttc ttgtataaga tgatacggat cttagtagga acgcttttga
    48961 aaattggcaa tggccgattg cctgaagata gtatcccaga tattattgcg aaaaaagatc
    49021 gtaatgcagc aggacctaca gcacaccctg aaggacttta tttgtatgaa gtgaaatatg
    49081 aataagaggt tatgatagaa gtggtcagct tcaagaaata agaaggtatt tacgaaaatt
    49141 acttctcaaa attttgcaaa atttcggctt attttcgaag aagctacttc tggaacaccg
    49201 tttaagaaag aggtcgtgag cctgtcattt aactctgagt cacaaagagc aatttcaaaa
    49261 aacagcttct catctttgat gaatatcgtg acttgtggac gaggcgttga taagtgaatc
    49321 atctttttgt tacctatttt ttctgtaacc aaaaaacgat ggaacgttgt tttgattgcc
    49381 cttggtgcgg acagtctgaa caggttccat cgtttcttta ttttctacgt cttcttctgt
    49441 gtgtgtttcg tggttgttct tctattgctg gatcaatcgt gccataaaag gggcgattgc
    49501 ggtcaaggta ccagacataa agaataaaca atgcaataca taggacaaaa aggattgcac
    49561 ctatcgtaaa tccttcaggc aagtaactga aagtgacagt atgtttacct gctggaactt
    49621 ttatcatcaa gaatgcgtct ttgaaattgc tgaccttgac tggtttccca tcaattttag
    49681 ctttccatcc tttgtcataa ggaatagttg tcaccaacat ggaatcttca gcggtattta
    49741 cagtcccaga agcttttctg ccagtggctt ccatttcgac acctttttct ttgatctgat
    49801 tcattgcggc ttgataggct acaacatcta gaccaacgac tttaggctcc atgaaactta
    49861 tttctttcgt cccataaaaa cttgcagtaa atgtcactgt tgtctcttga ggataatagc
    49921 caagatcata gtattgacca gaaatgttga tttgcgtttt tcgcgatgta ccattgacag
    49981 tgatcgtcgc actagaactt tctaattgcg caaaattggt tgggaacaaa cttaagtaag
    50041 cttgtgtatt tgcaggcaca tggacttccc aagtgagctc ttttggctgg ttatctgctg
    50101 tttctgagta agtgacgcca gtcgttgtct ttgtgatcgt cgtattcaac tgattcttca
    50161 aagtaggtgt atagaatgta aaatactgtt catttagacc agacaatgta ttgatcaagt
    50221 ttgtctgact ggtcaaatta tctgtcactg gctgctcaac atcattaacg gacaacggtg
    50281 cagtaaatgc tagtggcaat gcattgacat tctgatacag tgtatagtcg ccgctttgac
    50341 cagcttggcg gaagccatat ttactgaacg tgctttcgtt tttagaaatg ttatatttga
    50401 ttcctgtaaa cccatccatc agcaaagtat tattgttata acggatattc aaatttgtcc
    50461 ctcttgaacg gaaacctaat ttatccaggt aagaggaaga attacgattt cttatagaag
    50521 aaaacaaact gataccactg taaccatagt tgatcgaatc gtttgcagat actggatcca
    50581 gattttccaa gcggtaaaac gagtcggaat ctttttttgt ttcatttaca agagctttca
    50641 agtcaggata aggatcagta tataaactgc gggaagcata attccaatca tcaagaatgc
    50701 catggatcat actgttcgta ttgaccagtg cttcagcaga catgatcaat aataacaata
    50761 tactcagatg attgaatgaa agttttttat gctgataaaa tcccacagca aaagcataaa
    50821 tccctaagaa aaccactgtc aatacaaagg aagtcatcgt cacataggtg tagcttcctt
    50881 caggtttgat gccccatgcc accgcaaaga gagcagctac gaccaaaatg attcctaaca
    50941 acagcccacc atcgtcttgt tctatctttt cccatccttt tcctgcaagc aggagcacta
    51001 agaaagagaa cagataggca taacggaata aaaacatatt cggtgcatgc ataccatgcc
    51061 agaacaaatt caatggaaca agataaaaac ttgcgataag tatggcgaaa agactgccgt
    51121 acaaaaattt atttttcaac ggtactttcc gactggcaaa ataaaacaga cagaggacta
    51181 atggtagcag acctgcgtaa acgaacggaa tcgatccgta ttttgtcgtg tcataaacac
    51241 caatcatatt tttcatgatt agatccagat aagaagtcgc ttctgttttc aacgtagtga
    51301 tctgactcag tgcctcgcca tttgaccgaa gatccagcac tgctggcaat acaatgatca
    51361 ttgaagcgcc gcctgccagt aaagaagtga taccataagg aacaatcgtt tttttatatt
    51421 ctgaccagtt tgtcaataga cgggcgataa aatataagaa agaaaatacg ccaatcataa
    51481 aacccatata aaaactggat aaaaacaaga gtaaataact gataaataaa agtttcggcc
    51541 gtttaagatc cataacacga tgaatcccca aaatcactaa tggaagataa acaaatgcat
    51601 ccagccacat gatgatctcc gaatgtgcag tgataaatga gatcaatgcg taactgacgc
    51661 taagtgcaac atgcccccag cgaggaatct tgaacgtacg tgcaagaaac caaaaagcca
    51721 atccggcaca gccgacctta agcaaagtca gaacatacag tgcatctggc atcatctggt
    51781 ttggaaaaaa gaacaccagt ggcgtgaaga tcccgcctag atagtaagaa attaaagata
    51841 aataattcaa tcctagagaa gcattccatg tataaaaaat actttgcttt ccaagaagaa
    51901 catttcggaa gctggcatga aaattagaaa actgtgaaaa ggcatcactt gccaaaatac
    51961 ttctgctgct tccaggatag attccgatac ttagataaac aagtgctaaa atcaaaaacg
    52021 gaatcaggaa actagctgct gcgtagcgtc cgttttctct aaagaatgac tttaaatttt
    52081 ttttcatatt tattttccac caaatttcta tgaagttgta ttcagtttat catatccttg
    52141 tttttctctg cttaaaaaga gtctagtttt cacaaaaaaa taaaatttag aataaataac
    52201 ttcataattt gttcgtataa caaaaataaa cgcaaaaaaa gggtaggaat caaaagtccc
    52261 acccttaaaa atttttatta aataaaaaac cgttcactat ctgaacggtc caagtatcat
    52321 tcaattaaac gcgttcaact tttcctgatt tcaaagcacg agttgacacc caaacttttt
    52381 taggttttcc gtcgaccata acgcgaactt tttgtaagtt aggtttaaca gtacgttttg
    52441 ttgagttcat agcgtgtgaa cggttgtttc cactttttgt cttgcgacct gtaaagtaac
    52501 aaacttttgc catggtaatt tcctcctttg ccttgatttg gagcaataga ataattcagc
    52561 tcataccaga ctaacatatc atatagaatg ggaatttgca agtacatttt catagataca
    52621 attgacaatt gagaagaata attgtaaatt aaacaaggtt atacctgaaa ttttgcaagg
    52681 tttttgagta ctttgggtaa ctgcctttta tttcaagttg cgctatgata aaatatgata
    52741 gaagaaaaat gggagttttt tacccgttaa ggaggctcat tcatggctgt aaaaattcaa
    52801 acgtcagctg gaaccattga aattaccaat gatgtaattg caacagttgt tggtggcgcc
    52861 gcgacagatg tgttcggtgt tgtaggaatg gccagcaaaa atcaaattaa agataatatt
    52921 actgagattt tgcgtaaaga aaattactca agaggagtag ttgtccgcca agaagataat
    52981 ggtattgctg tagatgttta tacgattatc agctatggta cgaaaatctc tgaagtttcc
    53041 cgcaacgtcc aagaaaaagt gaaatacaat ctagaggcat tattaggcgt aactgccaat
    53101 tcagttaatg tctttgtaca aggtgttcgt gtactgccag actaggcagg agactggctg
    53161 gtaactcagc agtcgatctg aaggaggatt atctaggtga gtgtaacaga aataagtgca
    53221 agccagttcc aggaaatggt ccaggcaggt gcgaatcgtc tgcaagtaaa tgcagaatac
    53281 gtcaattcat taaatgtatt ccctgtgcca gatggcgata cgggaacaaa tatgaatcta
    53341 tctatgacta gtggagctaa ggcagtagta gattcaacct cagaaaaagt aggagaatta
    53401 gcagcaatgc tttcaaaagg attgctgatg ggtgcgcgcg gaaattccgg cgttattttg
    53461 tctcaattgt ttcgtggatt ttctaagcaa attccagatg ttgtctcatt aaatgcttct
    53521 gatcttgctg cagccttcac tcatggagtt gaaactgcgt ataaagcagt aatgaaacca
    53581 gtagaaggaa cgattttgac agtagctaga gaagcagcga aagctggaga aaagaaagca
    53641 aaaagtactg atgatgtcgt tgaagtaatg acagctgttg taaaaggagc aaagcgtgct
    53701 ttagctaaaa ctccagactt gcttccagtc ctaaaagaag tcggtgtcgt agacagtgga
    53761 gggcaaggac tgctgtttgt ttatgagggc tttttaagtg cattgaatgg agaattccaa
    53821 gcggatgaaa catatgaacc ttctccagca gaaatggatg atatggtcaa tgcagaacat
    53881 catcgcagtg tccaaggtca aatggcgaca gaagatatcc attttggtta ctgtacagaa
    53941 atcatggtaa aaatcggaga aggacctaca gtcgatagta cattcgatta cgaagaattc
    54001 cgtaactatt tagatggtat aggagattct ttacttgtgg tcaatgatga cgagatcatc
    54061 aaagtccacg tgcatacaga aaacccagga gaagtcttga attatggaca aaaattcggt
    54121 tcattagtca aaatcaaagt cgacaacatg cgcttgcagc atgagacgat tttggaacac
    54181 gatgaagaag tgaacgagtt tgcgaaaaaa gaaataccac gtatcccgta tggtatcgta
    54241 gcgatcgctg ctggtaaagg cgtccaagag ctgtttgaaa gtttaggcgc taattatgtt
    54301 atcagtggtg gacaaacaat gaatccaagt acggaagaca ttgttaaagc gattcaagaa
    54361 gtaaacgcag ataaagtgat tgtcttgcca aacaataaga acatcttcat ggcagctgat
    54421 caagcagcag aagtagcaga tatcccagta gcagttgttc cttcaagaac gatttcccaa
    54481 ggattgacag ctatgctttc attcaatgat caagcttctt tagaagaaaa caaagaaacg
    54541 atgacagaaa tgttgtctag cgttgtgagc ggtcaagtca ctcacgcgat cagagatacc
    54601 tcaattgacg gtgtagagat caaagaagga gactttttgg gcatgatcga tggaaaaatc
    54661 ctgatctcta acccagatat cacagcaaca gcgttaagta cactagaaca aatgatcaat
    54721 gaggacacag agatcgtaac gatcttggca ggtgatgaag gaacagttga acaagcaaat
    54781 gaatttgctg agaaactaac agaaaaacat cctgatttgg aaatcgagat ccaccaagga
    54841 gatcagcctg tctatcctta tctattttct gctgaataat ttctgtgtca gaatatcttt
    54901 ctaacacagt attcattcat aaaaggcctt cggttagtga tcaggtatga tcgctgacca
    54961 agtccttttt ttgttaaagg agggaggaaa aatttatgcg ttctttagat gatccaatca
    55021 ctatgctggc aggagtcgga gaaaaaagag cagctagtct tgccagcttg ggcatccaaa
    55081 cgattgaaga cttactgact tattatcctt ttcgctacga agatattcag gaaagaaatc
    55141 taaacgagat ccaggatcaa gaaaaggtta ctttgaaagg aatcgtagtc tcgcctcctg
    55201 tgatgaatcg atttggttat aaaaaaagcc gattgcaatt tcgtatgatg caagaacatg
    55261 atgtgttcaa cgtttctttt tttaatcaac cttatctaaa agaaaaagtc attttatcgg
    55321 aggaaatcgc cgtatacggt aaatgggatg caaagcgtaa agccttgaac gggatgaaga
    55381 ttttaggttc tcaaacaatg gatgactttt cgccgatata tcacgtcaac aaatcaattc
    55441 gtcaaacgac attagttgat ctaatcaaaa aagggtttca agaatacggc acattgattg
    55501 aagaaaatct gccaaacaac cttgtggaga aatatcgact gcttgaccga gcttctgctg
    55561 taagaagtat gcattttcca aaagaccacg aagaaaacca tcaagccaaa cgacgtgtcg
    55621 tttttgaaga gttcttttta tttcaaatgc gtcttcaagg attgaaaaaa gcagaaaaag
    55681 cagaaacgaa tggtttggag atcctttatg atgtccaaaa attgaaacaa tttactcaaa
    55741 agctaccttt tgaactgaca aatgcacaaa aacgtgtaac gaatgaaatc tgtcgggatc
    55801 ttcgcagtcc gcagcatatg cagcgacttt tgcagggaga tgtaggtagc ggaaaaacag
    55861 tggttgccgc gattgcgtta tacgctaccg ttacagcagg tttccaaggt gcgttgatgg
    55921 tgcctacaga aatcttggca caacaacata tggaaagctt gcaacagctg tttgatccca
    55981 atgaagtaac catcgcattg attacggggt caacgaaagc aaaagaacga cgtgagctcc
    56041 ttgaaaaact agagcaaggg gaaattaacg tcgtgatcgg cacacatgca ttgatccaag
    56101 atggagtcga atttcagaat ttaggtctag ttattacgga tgagcagcac cgttttggcg
    56161 tgaaccagcg gaaagtactt cgtgaaaaag gctggcgacc agatgtctta tttatgacag
    56221 cgactccgat tcctagaaca ttagctatta cagcatatgg tgagatggat gtatctatca
    56281 ttgatgaact tccagctgga cgtatcccga tcgaaacacg ctgggtaaga acacctcaat
    56341 tggacagtgt actggattgg acgaaaaaag aactggcaag aggacatcaa atgtatgtca
    56401 tctgtccgct gattgaagaa tcagaagcat tagatgtaaa aaatgcagtg gaaatctatg
    56461 aaaaacttcg tgaactattt gcaccaaaat atgaagttgg cttgttacat ggtaaaatga
    56521 agaatcagga aaaagaagta atcatggaag ccttcaaaga caaccagatg cagatattag
    56581 tttcgactac tgtaattgaa gtaggggtaa acgtgccgaa cgcgaccgtc atgctgatca
    56641 tggatgcgga tcgatttgga ttggcacagc tgcaccaact tcgtggacgt gttggacgcg
    56701 gaagtgatgc ttcctactgt atcttagttg ctaatcctaa aaatgaacta ggtgtggaac
    56761 ggatgaaaat catgacagag accaccaatg gttttgtact aagcgaaaaa gatctggaat
    56821 tacgtggtcc tggtgaagta tttggcttcc gtcaatctgg tctgcctcaa tttgcgattg
    56881 ctgacttggt gacggatgga aatgttttgg aggtagccag agaagaggct gcagcccttt
    56941 ggcaaataaa ggattggcag atgcttcctg agtatcagcc tttagcgcaa agcctccaaa
    57001 tagaaaatca ggataatcgt tatttcgatt agcagactgt gctatacttt atactgatga
    57061 cggaaaaagg agtggaaaca atgaaaattg ccgtagatgc aatgggcgga gatcacgcac
    57121 ctcaagcaat tgtagaaggc gtggctttag cgcagcaaga ttttccagaa gtagaattct
    57181 tactttacgg aaaagaagca gaaatcaaga aatacttaac aaatgaaaaa aacatcacga
    57241 ttatccatac agacgaaaaa atcaatagtg atgatgagcc agtaaaagca attcgacgaa
    57301 aaaagactgc atcaatggtc cttgctgcac aagcagtgaa aaacggtgaa gcagatgctg
    57361 tattttcagc agggaataca ggcgcgctac tagcagcagg gttgttcatc gtaggacgta
    57421 tcaaaaatat cgaacgccct ggcttgatgt ctaccttgcc agtagtaggg aaagaaggtg
    57481 ccggtttcga tatgctggat cttggcgcta acgcagaaaa caaaccagaa catttgttgc
    57541 aatacggtat tttaggttct ttttatgcac gtaaagtccg aggtatcgga cgtcctcgtg
    57601 tcgcactctt aaacaacgga acagaagcaa caaaaggtag tgaagtgacg aaaaaagcct
    57661 atgaactcct tcagaatgaa acaagcttga attttattgg aaacgtagaa gctcgtgagc
    57721 tactcaatgg tgtggctgat gtagtggtca cagatggatt tacaggcaac gctgttttga
    57781 aatctattga aggaacagca atgaatatga tgaatctatt aaaatctgct attctaaatg
    57841 aagggatcaa aggaaaaatg ggcgctatgc ttttaaaaga cggcttacgt tctttgaaag
    57901 cagaaatgga ttattccaaa catggcggtg ccgttttgtt tggcttgaaa gcaccagtca
    57961 ttaaaactca tggagcaaca ggccccgatg ctgttcgcta tacgatccgc caaatccaca
    58021 caatgcttga gacagatgta gttggacaat tagtcgaaca atttgaaaaa agcgaagaat
    58081 agtatttgga tatctgaagc gatccgttcc attgaaaaaa aggtggacat tcctgaaaaa
    58141 tgccagtaaa attagccatg gtgtaggtaa ttgacaagtg tatgattctt ggaggtgaaa
    58201 aagttgactc gcgaagaagt atttaacaaa gtagcgaaaa ttatttcaaa tcattttgag
    58261 atagataccg ataaagtgac ggatgaattg aacatcaaag atgatttaaa agctgattca
    58321 attagtatta tggaattcgt tttagagctt gaagatgaat tcggtacgga aatttcagat
    58381 gaagacgctg aacaaattga aacagtcggt ggcgcagtag attatatcag cagccatctt
    58441 aaataatttc aaataaaagc aaagaaggat aaaaagctgc atgcagcttt ttatccttct
    58501 ttttttaatc tttttgacac gtaaaagtca tttttctgat aattctggcg ataaacagaa
    58561 attatgttgc aaagtaaagc ggttttctat ataattatta ataattcatt acacaaagat
    58621 aagaataacc tttgttataa aacgatttat tctgtgtaat gtcctttttt attaagaaaa
    58681 acttccattt aggaagcaga gaggggtatt cgattgtccg ataaccaatt attagaagtt
    58741 cagaacctac atacaggatt ccgactcaaa gatgactatt acgatgcagt agatgacgtt
    58801 tcatttactt tagacaaaaa cgagatttta gcaatcgttg gggaatctgg gtgcgggaaa
    58861 agtaccttgg ctactacgat tatgggatta cttgatccta ataacacaaa aattacaggt
    58921 gagattttat ataacgatct gaatttaatc gacctgaacg aaacgctcta taataaaatc
    58981 cgcggaaatg atatcggaat gattttccaa gatccgttgt ctgcattaaa tcctctcatg
    59041 agaatcgaag accagatcaa agaaggactt tcctatcaca caaagatgaa tgcagaacag
    59101 cgtcaagctc gtgcactaga attgctagaa caagtaggga ttcctaatcc tgcgagagtt
    59161 ggacgccaat atccccatga actatcaggc ggtatgagac aacgtgtcat catcgcaatc
    59221 gcaatcgcct gcaaacctcc aatcgtcatt gcagatgaac cgacgacagc cctagatgta
    59281 accatccaag cacagattct tgatttactg aaagaccttc aggaagaaac aaaaacaggg
    59341 atcatcttga tcactcatga cttaggagtc gtagcagaaa tggctgatcg agtggcagtg
    59401 atgtatggcg gacagttcgt tgaagtagca ggtgtaaaag aactgtttga tcatcctaag
    59461 catccttata cacgctcttt actgaactct ataccacaag aaggaaatca tgatgcagaa
    59521 ctccatgtga tcgaaggtgt cgttccttct ctgaaaaaca tgcctcgtaa aggttgtcgg
    59581 tttgcaccac gtattccatg gataccagca agcgatcatg aagaagagcc tatccttcat
    59641 gaagtcgcac cgaaccactt ggtacgttgc tcctgctata agcatttcca ctttagagac
    59701 gaaaaaggag aggtgtagat gacagaatta atcacaatca aagacctgaa agttcattac
    59761 cctattcgca gtggattctt caatcgagta acggatcatg tatatgctgt agatggtgtg
    59821 gattttatta tcgaaaaagg aaagacatat ggtttagtgg gagagtctgg ctctggaaaa
    59881 tctactacgg gaaaagccgt tgtgggatta gaaaaggtaa cagccggaca aatcatgtat
    59941 gaaggaaaag atgtaacgaa gcgaagcaac cgcaaaaaaa tgggttataa caaggatgtg
    60001 cagatgatct tccaagattc aatgtccagt ttgaatccta aaaagcgagt gttggatatc
    60061 attgctgaac ccatccgaaa ttttgaacgg ttaagcgatc aagaagaaaa gaaaaaggta
    60121 aaaggactgc tagatatcgt tgggatgccg gaagatgcgc tatataaata tcctcatgaa
    60181 ttttcaggcg gacaacgtca acgtctagga gtagcccgtg ctgttgctac caatccaaaa
    60241 ctgatcgtag ccgatgaacc tgtatctgct ctggatctat ctgttcaagc gcaagtattg
    60301 aatttcatga aacgaatcca gcaagaatac ggcctcagct atttattcat ttcacatgat
    60361 ttaggtgtag taaaacacat gtgcgacaat atcgcaatta tgtacaaagg tcgatttgta
    60421 gaaatcggta caagagaaga catttataat gacccgcgac atatctatac gaaacgtctg
    60481 ctttcagcta ttccgcaaat cgatgtagaa aatagggaaa gccacaaaga aaatcgacga
    60541 agagtagaac aagagtatat ccaaaaccaa aaagaatact atgatgcgac tggtcgagtc
    60601 tacgatttgc gtacgatcac aactacacac aaagtggcgt tgaaagatgg aggtgcaagc
    60661 taatgtggaa aacgattctg cgacgtgttt tattgatgat cccgcaagtt attattttaa
    60721 gtgttctgat cttcttatta gcccaagcga tgccggggga tccatttacc ggtttgatca
    60781 atccaaatca ggatccggca gtgatcgaac agatgcgaca agcagctggc ttgaatgacc
    60841 catggtatgt ccagtacttc cgttggatcg gaaatgcttt gcaaggcgat tttggtcaaa
    60901 gtttcttata caaacgctct gttgctgact tgatcggcga acggatcatc aacactttat
    60961 atctatcgat cttgacagtt gtccttactt atttgattgc tgtgcctctg gggatgcttg
    61021 ctggccggta tcaaaattca atcttggata agattgtcgt aatctacaac ttctttagtt
    61081 ttgctgttcc tttatttatc ttcggcttga tcatgctatt tgtttttggt tatcgtttag
    61141 gctggttccc aacaagtgga tcacaaacac taggtttgca aggtggattt atcactcaat
    61201 ggatagaccg tttgaaatat attctgttac catcaattac ccaagcattt ttggcgactg
    61261 ccgtcacaat ccaatatctg cgaagtgaag taatcgattc gaaatcgctc gattttgtca
    61321 gaacagcccg ttccaaaggg gtaccgacga ataaagtatt cagtcgacat attttccgaa
    61381 atgcagcgtt gccgatggct tctcaaatgg ggtatgaaat cacttcgttg attgctggtt
    61441 ctgtagttat cgaaaagatt tttggttatc cgggagtcgg aaaactattt attgattcca
    61501 tcggccaacg ggactatacc gtgatcacat ccttagtatt gattttagga atcgcgacgc
    61561 tagtggggac attactttca gatatcatca tgagtatcgt tgacccgcgt attcggattc
    61621 aataaaacca atcagaaagg agaatggatc gatgagtgaa aaaaacaata cagcagttca
    61681 agaaagtatt cctcctatgg ggatacgaat gattgctcga gaatttaaaa aagataaaat
    61741 tgctattttt tcattaggtt tgctagtggt tttattatta gtgatcttta tcggtgcgat
    61801 gctgaccgat caagacaaag tgatgtatgt tagtatcttc gacaaatacg ctgcaccagg
    61861 aacagtttcg acacaaggac aaaagttcat tctgggagca gatgaaggcg gacgtgatgt
    61921 attaggacaa ttgatcatag gtgctagaaa ctctgttacg atcggatttg cgatcacgat
    61981 ccttacttcg atcatcgggg ttggattagg gatcatctct ggctactacg gagggatcat
    62041 tgacaacatc ttgatgcgga tcgttgattt tatcatgatt ctaccgatca tgctgatcat
    62101 tatcgtcttc gtatcgatta tttccagata caatgtctgg tcctttatat tcatcatgag
    62161 tgcattttat tgggtagcta aagcccgatt attccgaagc aagacattat ctgaagcaag
    62221 aagagattat gtcagtgcct caaaaacaat gggaaccaat gattttaaaa tcatgttccg
    62281 cgaaatcatg ccgaatctaa gttcattaat cattactaat ttgacgatga actttgcggc
    62341 aaacatcggt atcgagacaa ctttgacttt cttaggtttc ggcttgccgg caaatgtacc
    62401 tagtttaggt acattgatcg gttatgcaag taacggagaa gtcttagtga atcggcaatg
    62461 gatctggtta cccgcatcaa tccttatttt agttttgatg ttgagtatca attatgttgg
    62521 acaagcattc aagcgttctg cagatgcgcg ccaacggtta ggctagtata gaagcgaagg
    62581 gggaaatagg aatgaagaaa acgatttttg gatttgcagc gctgatgtct gctgtcgttc
    62641 ttgcagcatg cgggggcgga ggtacagata cctctggaaa caactctgga ggcaacggca
    62701 ataacaaaga ggaattaact tttccaattg caacaaaaaa taatgatgat gcaatcgaag
    62761 acggcgaatt agaagctgcg gtcgcaacgg acagtcagtt taaaggattg ttccagtggg
    62821 agttttacca agattcatat gatgcagctt ttatggctcc ttctcatgaa ccgctatttg
    62881 caaacgatga cgatttcaga atcacagacg acggagctgc aacgcttgat ctagatgaag
    62941 atacgaaaaa agcgacaatc aaagtaaaag acaacgtcaa atggtcagat ggtgaagatg
    63001 taacggcgga cgatgtgatt ttcccttacg aaatcattgg gaataaagat tacactggta
    63061 tccgttatga cgacactttc cgtaacatcg taggtatgga agaatatcat gatggaagtg
    63121 ccgacacaat ctccggaatc aaaaaaatag acgacaaaac agttgaaatc gaatataaag
    63181 aagtaaaccc aagcatgctt caatcgggtg gtggtatctg gtcatatgca gcaccaaaac
    63241 atacgttaga aggtgtagca atcaaagata tggaatcaag cgatcaagta cgtaaaaatc
    63301 cagtgacttt tggcccttat tacatgagta atatcgttgc aggagaatca gtagaatact
    63361 tgccaaacga gcactactgg aatggtacgc ctaaattgaa aaagatcacg atgaaatctg
    63421 taccgatggc aagtgcaact gaagcattga actctaaatt atatgatatg attttccaaa
    63481 tgccaacaga tacttacgat acctataaag aaattgctgg ctatacaaac ttaggccgtg
    63541 aacaaacttc ttatacttat ctaggattca agttaggtaa atggaatgca gatacaaaga
    63601 gtgtggaata caatccagat tcaaaaatgg ctgataaatc attacgtcaa gcaatgggct
    63661 atgcattaga taataatgca gtaggtgaac gtttctatgc aggtttgaga agcaatgcga
    63721 cttcattgat tcctccagta ttccagtcat accatgatga tgagatgaaa ggattcacac
    63781 aagatctaga caaagcgaaa aaactattag atgatgctgg ctacaaagat gtggatgacg
    63841 atggtttaag agaagacaaa gatggaaata aactaacaat caactttgct tcgatgtccg
    63901 gtggggaaac agcgcaacca ttggcagatt actatatcca acaatggaaa gaaattggtt
    63961 tggatgtcca atacacaaca ggtcgtctga tcgaattcaa ttctttctat gataaattag
    64021 aaaacgatga tcctgaaatt gatgtttacc aagctgcttg gaatacagga actgatccaa
    64081 atccaagtgg actatgggga ccaaatgctg cgttcaacta cactcgttat gaatcagaag
    64141 aaaatacaaa attgatcaac gatatcagtt caagcaaagc atttgatgaa gagtaccaaa
    64201 aagaagcata tcaaaaatgg caacaatatg catttgaaga agcatttgcg attccaacgt
    64261 tgttccgtaa tgaagtattg ccagtcaacg accgtgtcaa agactgggat tggtcttatg
    64321 atgtaccaaa cccatgggca aatgtttctg ttacagcaga ttcacgttca taatcactaa
    64381 aaatgaccga aaaagggcga tgtccttttt cggttttttg atatttttct gtttatttct
    64441 ctaatattca ggtcaaggcg ctgatttcat gacttctcca ataaacggtg ttcaaagtcc
    64501 agtttctcgg tattaagtca aatttatgca aaaatatgga aagccatttt cacaaaattt
    64561 tttcttcata ctcgaaacta aacgaatttt tcacaacttc tcgtcaatca ctaggattat
    64621 taaagcttta cttacctttt gaccgaacca tttcaaattt gacaaaaaac cagtataata
    64681 aggaagtatc gaaaaaatat ccataaaagg aatgtggaaa atggacaacc agctgacaaa
    64741 agaactaaaa gaaaactata acatcgtttt tcacgatcta aatttgcttg aacaagcttt
    64801 tacccattca tcctatgtga atgagcatcg caatctgcaa ttatcggata atgagcgact
    64861 tgaattttta ggagatgccg ttttagaact gatggtttct cagtatttat tccgtttata
    64921 tcctcatttg ccagaaggaa aattgacaaa aacacgagct gcgatcgttc gcgaagacag
    64981 cttgtcgaaa tttgccaaag aatgtcactt tgatcaatat gttttgttgg gcaagggaga
    65041 agagaattca ggaggacgta cgcgaccagc attgctttgc gacctattcg aagctttttt
    65101 aggcgcgtta tatcttgacc agggattcga cacgacccat gcattcatcg aaaaagtgat
    65161 ttttcctaaa gtcaaagcag gtgctttttc acatgagatg gatcataaaa caaaactaca
    65221 agaagtcttg caaaaatcag gtgatgtatc aatcgaatac cgattgatca atgaagaagg
    65281 tccagctcat gaacgagtat tttggatcga agtttatgta gatgatcaat tgattggcac
    65341 tggacaaggg aaatcgaaaa aattagcaga acaagctgcg gcggaaaatg cattggcagc
    65401 actgtaaaag taagtgaggg aaagctttgt atttgaaacg aattgaaata gccggtttta
    65461 aatcatttgc agacaagaca gtcattgatt ttgaaaatag cgtcacagca gtggttggac
    65521 caaatggcag cggaaaaagc aatattacag aggctatccg ctgggtatta ggagaacaat
    65581 ctgctaaaag tctgcgaggc ggaaaaatgc cggatatcat ctttgccggt tccgataccc
    65641 gtaagcagct gaatattgca gaagtcacag tgattttaga caatagtgat cattatctgc
    65701 cattggagta caatgagatc agtgtaaccc gccgttatcg acggactggg gaaagcgagt
    65761 ttttcatcaa taaacaaagc tgcagattaa aagatatcca agaattgttc ttagattctg
    65821 gattaggaaa agaatcgttc tcaatcattt ctcaaggaaa agtagaagcg attttcagta
    65881 gtaaaccgga agaccgtcgt gggatctttg aagaagcagc tggtgtcttg aaatacaagc
    65941 agcggaaaaa gaaagcagaa cagaagcttt ttgaaacaga agacaacctc agccgcgtcc
    66001 aagacatcat ccacgaattg gaagaacagt taactccttt ggccgcccag agtgaggcag
    66061 caaaggagtt tttacggcta aaagaaacac tgactcaaac cgatgtctct ttgatggttg
    66121 ctgaaatcaa gacagcaaaa aaagattggg acaacaaaca agcacagctt gcgaaattca
    66181 atctagaatt aggcaaacta tctgagtcga tccaagaaca agaatccatt ttggcgaagc
    66241 agcgtaaaga aaatgcgcaa gccgatcgtc tgatcgaaaa aaatcagcaa gtattattag
    66301 atctttcgga aaaactgaag cagacagaag gacaaaaaga tgttttgcag gagcggacaa
    66361 agcatacaca aaaaagctcg caagaatatc aaacttcatt agcagaagca caaaaaaagg
    66421 ttaaacattt tgaaaagctt caagaaagct tgatgaaagc agcagcagaa aaagaaacag
    66481 agatccaaaa agctgaagca aatctcataa aaacacagca agaattagaa aaataccaaa
    66541 aatcaacgaa agaattattg gcagaattaa gagatcaata tgttgatttg atgcaagaac
    66601 aagcagctgt aggaaacgaa ctgaagtatc tagaacgtca atatatacaa gaaacagcaa
    66661 aaagcaagca gacgttagcc aagcaatcgg aagtagaagc atcagtagac cgattgatct
    66721 tacaaaaaga agaattgaca caaaagcagg cgcagctaaa atcatcttta actgaaacaa
    66781 aagagaagtt agaaatgatc caacaaaacg ggaaaaagtt ccaagaagca ttagcaaaag
    66841 aacagcctaa aatgtatcaa ttaatgaatc aagtccagca gctacgtgct cgtaagaaaa
    66901 gccttcaaga aatccaagaa aactattttg gtttttacca aggggttcga ttggtcttgc
    66961 agcataaaca gcagctttcg ggtattgtcg gagcagtggc tgaactgatc gatgttcctg
    67021 cagatttcac gttagctatc gaaacagctt taggtggggc agcccagcat gtcatcgttg
    67081 aaaatgaaaa agatgctcgg caagccatca cgtatttgaa acagcaaaga ggaggaagag
    67141 caacattcct tccactgacg acaatcaaac caagacaatt accggctcat atattgacac
    67201 aagcagcagc tgtagaaggg tttataggga ttgccagtga acaagtcagt tatcccgatc
    67261 aaatccaaac tgtggttcaa aacctgctag gaacgatcct tttagccaaa gacttaacta
    67321 gtgccaatgc aatcgcgcaa acgatccgct atcaatatcg agtggtttcc ttagaaggtg
    67381 atgtgatgaa tgccggagga tccatgacag gtggagcgaa taaacgagga aaccaaggca
    67441 gtttgtttgt acaaaatcaa gaattgaaac agttgactag tgaatttgaa gaagcagata
    67501 aacaactcca agcacaagaa aaaaaagttc aggagctgca acaagaaaca gctcgtttag
    67561 ccgaagaaca agaagttttg cgtacacgag gcgaacaatt acgttttgaa gaacaagaag
    67621 cgacaaatca gctacaaaac atcataaatg aacttgaacg ttttgaaaaa gaaaagcaaa
    67681 tctcaacttt tgagacacgt gaactgcagc agtttatcga agattacgaa aagcaaacga
    67741 acgaattgaa agacaaacaa acagatcttg aatcgcaacg acaaaaaatc gacgaagaaa
    67801 tcaaatcgtt aagtcaagaa agcgaccaga tggaagccag aagagcacaa gtacaaagtc
    67861 aaaaagcaca agaacaagca gatcttgctg tcttgaaaga gcagtttaat catctgcaga
    67921 tccagctccg cggtgcccga gtccaaaaag cagaggcaac cgaacgtcaa gaagcgatag
    67981 aaaagcagtt ggcgacattg acagcagact tttctgatca tgaagtcaca gaagaaagtt
    68041 tggaaaaaca aattaacgaa ttatctgctc agcgagaaac attaaaagcc gagttggcaa
    68101 aagccaaaga gcagcgagat agaaggcaaa aggagatcga taagcttgaa gcagtcttgg
    68161 cagagcgtaa tcgtgagcaa aaagcacgac tgtcggaaca atccaaatta gaagtccaaa
    68221 aagaccgagc tgaaatgatt ttagataatc atttgaccta tctgcagtca gaatatcagc
    68281 tgacatttga gaaagcttcc caagactatc aagaaacaac cgatatcgaa gacagtagaa
    68341 caaaggtttc atccttaaaa gaacagattg aaaaactggg accagtaaac ttaaattcaa
    68401 tcgaacaata cgaacaagtc agtgaaagac atacattctt agcaacacag cgagatgatc
    68461 tgttagcagc gaaaaaccaa ttgtttgaaa cgatggatga gatggatgat gaagtgcgga
    68521 caagattcaa agaagtattt gaagctatcc gtcaagaatt caaaattgtc tttccaaata
    68581 tgtttggcgg cggtaaagct gaattagtac tgacggaacc aactgatttg ctgaaaacag
    68641 gtattgagat tgaagtacaa cctcctggca aaaaactgca aagtctaagt ttgctttctg
    68701 gaggagaacg agcacttaca gccatcgcgt tgctcttttc cattatccgt gtctgtcctg
    68761 ttccgttttg tatcttagat gaggtagaag cagcgttaga tgaagccaac gtgaaacgtt
    68821 ttggtcgtta cttgagcgat ttccaagatg acacacaatt tatcgtagtc acacaccgca
    68881 aaggaacgat ggtcgcagca gatgtactgt acggagtgac gatgcaggaa tccggtgtat
    68941 caaaaatcgt ttctgtacgg atggaagata tcaatgaaga ggcgaaaatc aacgaaacga
    69001 aagtgtagga acgaaaatga tcaaattagt agcaatcgat ttggacggta cattattaaa
    69061 tgaacaaaag ctgatttcag atgagaataa acaagcatta gcacaagcaa aacagcaagg
    69121 ggtcaagatc gttctatgta caggacgccc cttagctgcg atggcgcatt atctgcaaga
    69181 attaggactg gtagatgaag gtgactacag catcactttc aacggcggtt tggtacaaaa
    69241 aaatgatact ggtgaaatca tggaaaagaa agtgatggaa gtatcagata tccaacgctt
    69301 atacaaactg gctcagcaat tggatctgcc actagatgtt ttgtctgaca atgtggtttt
    69361 acagctgcct agtgccccaa ggaagcaatc cttgtacaat gtgttgaata agctgctgca
    69421 attccaacca gcggatataa gcgatattac agatgaattt gtgcttaata aggcagtaat
    69481 cgcttatgac caagaagaat tagatcctaa aatcaaagaa ataccagcag aattccatga
    69541 aatgtatgag atcatcaaaa caagaagtat gcttttggaa tttatgccaa aaggtgttac
    69601 aaaagcttat ggtatttctt tattggcaaa agatcttggt ttgaaacaag aagaaatcat
    69661 ggcgatcggt gatgaggaaa atgatttacc gatgatccaa tatgctggac taggcgtagc
    69721 gatggagaat gctgtgcctt tcgtcaaaga agcagcagat ttcgtgacag ccagcaatga
    69781 agaaaatggc gtagccaaag tgatccaaaa atttgtatta gagtaggggg agtcaaatgg
    69841 gattttttga taaaatcaag cgtgctttta ctggcgaaga gaaaacagaa gaagttgaag
    69901 tacaggagaa gtacgacaag ggtttagaaa agacgcgtaa aacatttggt gaacggatga
    69961 atgagttgtt tgccaatttt cgaacagtcg atgaagactt ttttgaagaa ttagaagaaa
    70021 cacttatcgg tgcagatgta ggttttgaaa cagcgatacg aattaccgaa gcattacgtc
    70081 aagaagtgaa actcagaaat gcgaaaaaat cggcagaagt ccaaaatgcg atcatcgaga
    70141 aacttgtgga tctctatgaa gcggaaggaa tcaatgaagt aaatgaacta aatatccaag
    70201 aagacggact aacagttatt ttgtttgtcg gtgttaatgg tgtagggaaa acaacaagta
    70261 ttggtaaact tgcccatcag ttcaaaaacg aaggtaaaaa agtattgatg gcagcagcag
    70321 ataccttccg cgctggagca atcgaccagt tagttgtctg gggcgaacgc gctggtgttg
    70381 aagttgttcg tggcaatgca ggaggcgatc cagcagctgt cgtattcgat gctttggaaa
    70441 gagcaaagac agagcaggca gatgttttac tagttgatac tgcaggccga ctgcaaaata
    70501 aagtgaactt gatgaacgaa ttagaaaaaa taaaacgagt aatccagcgg gaattaccag
    70561 aagcacccca agaaacactt cttgtattag atgcaaccac tggtcaaaac gcgatggttc
    70621 aagcaaaaca attcaaagaa acaacagatg tgaccggtct tgttttgaca aaattagatg
    70681 gtacagcaaa gggcggtatc gtacttgcta tccgtaatga attgcattta ccagtgaaat
    70741 tggtcggtct tggtgaagga atcgatgact tggagccgtt tgatccaaat gattttgtcg
    70801 ttggattgtt caaaggatta ctaaaagaag aataacccat gtctaaaaag caggagctgt
    70861 gacaaaagtt gcagctcctt gtttgaatga ttgtttttaa catagctgtg tttttgatgc
    70921 cttcattttt atacttattt gtaagcggtt ctcaaacaat ttcgttcttt ttcttagact
    70981 ttttgattat aattagattc atatgaattg gaggtcactt aatgatgaat tttaagcaat
    71041 tattattgca tgtcaatgcg cgccctttta tcgaccaagc tcgatttggt atagaacggg
    71101 aaggacagcg ggttgatctt gcaggaaatc tagcaaaaac cgatcatcca gcaatctttg
    71161 gcgatcgatc ctatcacccc tatatccaaa cagattttag cgaaacacaa acagagatga
    71221 tcacccctgt taccgattct attcccgaat tatttcagta tctcgctgct gtttatgatg
    71281 tgactgctcg ttctataccg aaagaagaga tgatctggcc attaagtatg ccacctgcct
    71341 taccggaaaa agacgaagag atcattattg caaaattaaa aaatttcgaa gatgtcttgt
    71401 atcgacgtta tttagcaaaa gaatacggga agcgaaaaca gatggtaagc ggtattcatt
    71461 tcaattttga atttggcgat gagttgctaa gaacattgtt cagccatcag gaagaatttc
    71521 aagatttttc cgaattcaaa acagaacttt atttgaaaac agcgagaaac tttatgcgct
    71581 atcgctggat gatcacttat ttattcggtg cttcaccaat gagtgagaag aactactttt
    71641 tagatgaatc acatccgcaa gaacctgttc gcagtattcg caacagtgcg ctgggctata
    71701 cgaatcatcc aaatgtgaaa gtttcctatg cttctatgaa acagtattta gcagatatcg
    71761 agcgaatgat cgaagaaggg aaactttcgg aggagaaaga attttataca ccgcttcgtt
    71821 tccgaggcgg aaagaaagtc gcagatttag caacaacagg tgttcgttat attgaattgc
    71881 ggaatatcga tttgaatcct tatgcaagat tgggtatcaa tccagagcaa gttcggttct
    71941 tacaattatt cctgatgtac atgttatgga cagaagaaaa agaagactgt gaccaatggg
    72001 tagcagaagg tacgactcga aataacaaag tagcactaga acaaccatca gatcaaacag
    72061 aatttcatca agaaggtaga gaaattcttg aaggaatgaa gcaaatgctg gttgaattgg
    72121 attggttgga ttctctttat ttagtagagg aagcattgac tcaaatggat catcctgaac
    72181 aaacgttagc agcgaaactc tatcaagaag cacagctatc gagtcagcaa gaagttgctg
    72241 tggcattggg acatcaatat tataaagaaa gccatgaacg tccctatcag ttggccggtt
    72301 ttcgcgaaat ggaactttct actcagatat ttatgttcga tgccatccaa aaaggtgtcc
    72361 aagtcaaagt attagatgag tcggatcaat ttttgcgtct gcaattccaa gaccatgtag
    72421 aatatgtgaa aaatgcaaac atgacaagta aggacagcta tatcgtccca cttatcatgg
    72481 aaaacaaaac agtaacgaaa aaagtcttaa aagaagctgg gttccgggta ccaggaggcg
    72541 cagaattttc atccatggaa gaagcggtaa aagcttatcc gagatttgcc gagcaggcat
    72601 ttgtgatcaa acctaaatca accaattacg ggttaggtat cacgattttc aaggaaggag
    72661 ctagtctgga agattatcaa gcaggtttag ccattgcttt tcgtgaagac agttcggttt
    72721 tagtagaaga atttatgccg ggaacggaat atcgtttctt tgtgatcgac ggagaagtcc
    72781 aagccatcat gttgcgagtc cctgctaatg ttattggtga cagtatccga acagtgaaag
    72841 aacttgttga agaaaaaaat agtgaccctt tgcgtggaac gaatcatcgt gcacctttag
    72901 aattgatcca attaggtgaa ttagaacaat tgatgttgaa agaacaaggg ttgacgatcg
    72961 aatcagttcc ccaagccaat caaattgttt atctaaggga gaactcaaat atcagtacag
    73021 gtggtgattc gatcgatatg actgatgaat tttctgaagc ttacaaaaaa atcgccgttt
    73081 ctgcggtaga agcactagga gctaagatta gtggtatcga tttgattata ccagataaag
    73141 aaatcgatcc tacaactgat aaaaaagcat atgggatcat cgaagcaaat ttcaatccag
    73201 ccatgcatat gcatgtttat ccttttgcag gaaaaggcag aagattgacg atgaatgtat
    73261 tgaaattgtt atatcctgaa gtattttaaa agaaaaagct tttgacagat tgtcctattt
    73321 gatgtcaatc tgatcaaaag ctttttttgc atgtaaaaat ttatgtgttt tttcgtttta
    73381 aaataaacga tcccagaagc tttttttctt ttttggtttt tctttttcag ctggcgaaga
    73441 gttttcttct gggtattttt tttcgatatc aatcacaggt tcatttactg cttcttttgc
    73501 tgttaagagc aatccgaatt cctcaggatt tgcagtgacg taatcgttga ctacagtgaa
    73561 acggctattg tttttcgttg ctagctggat atattggttt tggacagaaa ggggtagagc
    73621 cccattcaag agtatggaag catctggatg ttttttgagt tcttttaaaa agttttcttt
    73681 gttttttggt tggatcattt cagcaacagt catactaaga tagcagcgtt ccctgaatgt
    73741 ccctaaatat ttatgctgtt cttcagggtt cactaaaggt gtaccataaa gtcccttatc
    73801 caaatggctt tttacatcat cttgtgccat aaaaaatacc ctccttcttc tctttgtctt
    73861 tcttacgatt atagcatatt cccaataata cctaaaacat atgaaaaagc ggttgctttt
    73921 gttcaacgat tcacttaaaa taagaatgaa aatcattctc aattagaaag gtggattgga
    73981 tgcgctacgg acgactagta gcattattag ttattttaag tagtatttca ttgttcatcg
    74041 gagtatcgaa tgtacaattg tcagaactgc tccagttaga tgggcaaagc ttacaaatct
    74101 tgctagtgac tcgtttgcca cgaacgattt gtttgatcct tgtgggagcg accagtagta
    74161 tttgtgggtt gatcatgcaa catttgaccc aaaataaatt tgtttcacca acgactgcgg
    74221 gcacgatgga tagtgcgcgt ttaggtattt tagtggctat gattttccta cctggtgcat
    74281 ccttgattgt ccgatccttg acagcatttt gctttgcttt tgcaggaaca ttgctttttt
    74341 tatcccttac gcgattgttc ctccagaaaa atcaattgat gcttccgttg attggagtca
    74401 tgttagggaa tatcattggt tcagttgcta ctttttttgc ttatcaattc cagttggtac
    74461 aaaatatgac ttcatggctt caagggaatt ttgcgactgt gatacgagga aattatgagt
    74521 tattgtatgc tgttgttcca ttgttgctct tggtttggct atttgcttac cgatttacga
    74581 tcattggtct gggcgaatcg tttgcagtaa atctgggaat agattaccag aagatgcagt
    74641 ttttaggcat tggcttagta tcattggcta gtgcagtcat gttgatcatg gtaggaagca
    74701 ttccttttat cggagtgatc attccgaatc ttgtctctag aatatatgga gatcaagtgc
    74761 acaaaacaat tggcgtaact gctttagcag gtagtttgtt cttagtattt tgcgatcttg
    74821 tcgctcgcgt gttgattttt ccttatgaaa taccagtcag tgtgatcgtt ggaatcatcg
    74881 gtggggctat cttcctttat cttctgataa ggggacgacg atatgcttaa aaaaaagcca
    74941 tctattttta ttggtatgct tgttcttgtt ttatttgtta caggaatgta cttgacgatc
    75001 catacatatg gaaactggca ttttgcatgt gcattgagga gtaagaaaat ttttgcattt
    75061 atccttgtct cgctagctgt cagcagtgcc acaatcagct ttcagacaat tacgcataac
    75121 cagtttttga ctccttcagt attgggactt gagtcgttat atgtccttgt ccaaacggtc
    75181 cttttcttct ttatcggagg agtgacgatg cttcagcaga caggtacagt ttttttctta
    75241 ttgaacgttg ggctgatggt cgggctgagt ctattgttat ttttctttct tttgaaaaaa
    75301 atgagagcga atcttttttt attactgatg tcagggatga ttttaggtac gctttttggt
    75361 agtgtcagta cctttttaca agtcatcatg gatccgaatg aatatgattt gcttcaaggc
    75421 agattatttg caagctttgg caatatccag agtcagtatc ttttgcctgc ttctttgatc
    75481 attatcggct gctggtacct gttatttcga tatcgacatg tgctagacgt tttccatctc
    75541 ggaaatgaac aagcagtaaa cctcgggata gacacagatc gttttgaatt tttgatttta
    75601 tgttgtgtca gtcttttgac agggacatca acggctcttg tgggtccagt tactttttta
    75661 gggtttattg tcgcaaatat cagttatcgt gtcttttcta cttatcgtca tggtcagcta
    75721 tttatcggaa gctttctggt agctatgctg tttctgacag gaggacagct cgcagtagag
    75781 cagattttcg gctggaatac aacagtgagt gtcgtcgttg aatttgtcgg aggaatttat
    75841 tttgtcacaa aattgattcg cgaaaggaag agtatcctat gattgattta caaaaggtca
    75901 ataaactgta ccatggaaaa tcagtggtta aagatgtaca gttaacgatt cctgaaaaga
    75961 aattgactgc ttttatcggt ccaaatggtg ctggaaagtc aacggtgttg tcgatgatca
    76021 gtcgtttgat accaaaagat acaggtgaaa tctatttaga ccataacgaa gtaaaggctt
    76081 ggaaatccaa tgaattagcc aaaaaattat cgatcctacg acaatcgaat gaaataaatg
    76141 tccaaatcac cgtgaaagaa ttagtagaat ttggacgatt tccttatacg aaaggaaaat
    76201 tgacgacaaa agacgaggaa atcgttcagg aatcactgga acaccttggg ttagaagaaa
    76261 tagcggatca atcgattgac actctttcag gcggtcaact ccaacgtgcg tatattgcaa
    76321 tggtgctagc gcaagacacg gattatattt tactggatga acctttgaac aatctagata
    76381 tgaattttgc ggttcaaatc atgcagattt taaaaaattt agtacaagaa atcgggaaaa
    76441 caattgttat tgttcttcat gatatcaact ttgctgcaag ttatgcagac gaaattgttg
    76501 caatgaaaga tggacagtta tttacgcaag gaacgaccca agaaatgata aaaaaagatg
    76561 tattggatga attatacgaa atggacatac ggatttgtga gattgaaggc cgcagattct
    76621 gtctttattt ctaaaactaa cattaggaga gaagagatga aaaaattagt agtaggtatc
    76681 ttgattctag catcatttgg tttagcagca tgtggaaata gcaacaacac cagtcaggca
    76741 gacacaaaaa aaagcagcac acaaactgaa actacattga cgataacaga tagtaatgga
    76801 gaccaaatcg aggtgccaaa taatccagaa aaagtcgtcg tattcgacaa tggttcttta
    76861 gatacgatgg atgctcttgg tgttggagat aaggtagttg gagcagctac aagcagcctt
    76921 cctgagtatc tttcatccta taaaaaagta gaatcagcag gtggaataaa agaaccagac
    76981 ttagaaaaaa ttaatcagct tcagccagat ctaatcatca tttctggccg acaaagagat
    77041 tttcaaaaag atctaagtca aattgctccg accattttcc tttctttaga tgcgaaaaat
    77101 ccatgggaat ctttccagca aaatgtcact gctttagggg agatctttgg taagcaagaa
    77161 gaagctaaaa ctcaattaga ggaattatct agtgcaatcg atcagacgaa aaagaaagca
    77221 gaagctactg acaaaaaagc actagtcaca cttgtgaatg aagggcaatt atcagcctac
    77281 ggatctggtt ctagattcgg tttcatccat gatttatttg gctttgaaca agcagatgat
    77341 caaatcgaag catccactca cggtcaaagt gtttcttatg aatatgtgct ggaaaaaaat
    77401 ccggatatct tatttgtagt agacagaaca aaagctattg gtggagacga cagcaaagat
    77461 gatatttctg ccaatgaact ggtagcacaa acgaatgctg gtaaaaatca gcagatcatc
    77521 tcccttgaac cagatgtctg gtatttaagc gggggcggtt tagaatcaat gaaactgatg
    77581 atcgaagatg tgaatcaagc atttaaatag cataaataac agaggattaa actctcatac
    77641 tatgtaacaa taatgtttct tacattctta aatagcaaga gcctatcctc aaagaagtta
    77701 tcaaaaacca tccgtaaaat cgtattgatg attttacgga tggtttttat ttatttgaga
    77761 aatctttttt caacgtgaat tcattatcta catcatacgg gttgattcta gaatggggag
    77821 tggcaaaaaa tagtgtgatc cattttttca gcatcaagat cgcctccttt gatttgaatc
    77881 aaaggtacaa agcgaaactt agataaaact taaatttaga tatttttatt ttgtaccgat
    77941 ctcttcttta aacgatgttc catctgctgc ttctcggcaa taagtccact agactagaaa
    78001 atatgagaag ctattttctg tccagcgttc ttattactca aagcaaatcg cagttgtcac
    78061 aatctcttct aaacgatgtt ccatctgctg cttctcggca ataagcccac tagactagaa
    78121 aatatgagaa gctattttct gtccagcgtt cttattactc aaagcaaatc gcagttgtca
    78181 caatctcttc taaacaatgt tcaatcagct gaccttcggt attagctcaa agcactgatt
    78241 tcacaacctc tatttaggca tgtgtctcag caagcggttg atagttgatg atctgcattt
    78301 ttcgataaaa atcggcggga agcttactcc accgttttaa taattgatag aaataactct
    78361 cttctgcttt gattttatac tcgcttaata tcaatccaaa actattcgtt ttttttgaag
    78421 ctaatttttt ataaatatcc aatgctttgg ttttatcttc attgacaaag agtgttttta
    78481 cttcaatata agaaccctcg atattttgtg tttcttcgat aaaatagatg ttttttatat
    78541 attccttcat agtgattcct ccaaagaagt cttttatttg ataagtttac tctaccgaag
    78601 agttgttaat aatccgtgaa caaaaagtaa ttctttttcc aatagttgtt aaaggttttt
    78661 tattttttat agtatttttt gttatttaag aaaggaataa ggttaaacaa ataacaggtt
    78721 gctttttggg tctttttccg ttcaagaaac tgaacgaaga aaagggaaag ttgtctcttt
    78781 tgtgataaga gaaatcataa taaacgaatg acttactttc caataaattg agaacagtca
    78841 gaaccagaca aattagttgc atctgatgaa taaagtgatt attctatgac atgaggtgat
    78901 acagatgaaa ttagaagtga caaaagaagc acaagaagta ttgaagaata aattagaagc
    78961 agacgatcaa cttttattag atatcgaaaa cggtgacggt ccatttgcag aaagccaagt
    79021 cagttgccaa ttggatacgg catttcgatt gatcattgtc aaaaaagata cacaaacaga
    79081 tctaagtctt tattctgtag tggctgatac accagttgga ccaatcaaaa tcaaagacag
    79141 tgcaatactt tacatggatg atccatccac acttgcttta gaaccaactt ataatagttt
    79201 acaattaaaa ggaccaagcg gcttgagaaa aggcaacttg caagttgttc gaaaagacta
    79261 gagggataaa atgggaaaat tggcgatcat cagcgaccta catgtggaca tcaataaatt
    79321 cggcgaatca gagctgatgc agctttggca agttttgcaa aagcacaaga tcactcggct
    79381 tcatctagcc ggagatacgg ctaataaagt agaccgttgc ctagctgttg tcgaattttt
    79441 cgtcaataaa ggattatcta cgacatttca tttcggcaat cacgagttgg cagatgtgcc
    79501 caatgaacag atgatggacc attttccaga cccacatttt ttaaatgaac ggtatattgc
    79561 tttaaatgag cagaccgttc ttttagggat gaatggctgg tacgactatc agttttccga
    79621 attgaaagat tacgaggcaa tcgtacgaat gaagcgtttg tattggtatg atcggttcat
    79681 ccagcgtggg aaaacagatc tcgaggtcaa tgcagaaatg cttgcagctg caaaaaattt
    79741 gctagaccag ctggaagcaa aaaaacttga ggtgatttta tccactcatt tcgttcctaa
    79801 acgggcattt atcatgtatc aatctgctcc ttatgagcgt tggaacaaat taaatgcatt
    79861 tttaggatca gaatcattcg gagaattact tgaccgttat tcaaatatca aacaagtagt
    79921 ttttggccat acgcatcgtc gctttgaaga taaatccatc ggtcacacga tttacagctg
    79981 cagacctttt ggttattatt atgaatggca gctgacccga gattttgtct tgaaagaaca
    80041 gttgctagac agctatgatc ctatgaaatt acgtgtcctc ttgcgtgccc atcacccagc
    80101 ttttcaggcc tatcaaacac aacatttgca agaggaattt gaacaagcga tgacaatcgt
    80161 tccgtattga gacagcatta gtaatgtgta aaagaaaata ccttgtaaaa cataaggata
    80221 agtaagagca gtagatccat ttatcgtgga tatgctgctt tttttgcgga aaataatcag
    80281 cgaatgttta tttgatcgga tgatttgtaa ctcgcagagt actagatgca agcgtgtatt
    80341 ctttttttga acgataatca caaaaaaaaa tataatatac attttttatt taattataat
    80401 taatattgat tgaagtctag gcagtcaagt cacattttga tagataggag ggggacttac
    80461 gaattatttt aaaggctatg acagctgtat ttctagattg tgtttgcatc aagttgcaat
    80521 aaaaactaga aatcaaatcg ggctgataat catttataac taatcgatac ataggaccaa
    80581 atataggtct atgttctttt atttcataag tatcgtaaaa cagaattttg ctatggatta
    80641 atccaatcga ctgatatgtt tagtaaataa agaaagagga atgtcaatga tgaaaaaaga
    80701 aatcgtatta acagcagcaa tgatgttatt cagcatggta gcaagtacga cttttgtttc
    80761 tgcaactgaa gtatacccaa aggaatataa cacagaagga acgattacat ttgaagcagg
    80821 agatgagggt gtaactcctc ctgttgatcc agagaatcct gatcccaata aacctgtcga
    80881 tccatcagat cctccaagcc ctggaacagg aggggcatta tcgattgatt atggatcaaa
    80941 attcaaattt gggactcaaa aaatttctac tgcggataaa acgtattatg cagctgctga
    81001 tgtgatgaac gatgggtcta gaaaaccgac atatgtccaa gtgacagata ggagaagtac
    81061 cttatctggg tggaaattaa gtgtctctca accagaacag tttaaaactg ccagtgggga
    81121 tgaactagtt ggagcacagc tgaaatttac gaaagggcag gctgtttctt tggttgatcc
    81181 aacatatacg ccgcaaacgg tgaattctga attaacgttg acaccgggag gaaacaatac
    81241 gttagcaatt aatgctaaat caggaacagg tgtggggact tgggtctatc gatttggtgc
    81301 aaatgaaaat gaaaatcaag atgcggtaca gctttcggta cccggtaaat ctgtcaagtt
    81361 agcgcaacaa tattccacta aattagtttg gacattagaa gatacaccta acaactagtt
    81421 tactgaaaag aactgttaaa aataaatacg tagtcatatt gtcttgcgag gtaatcgagc
    81481 aaaaattgtc aaaggctagg ctaaatttgt ttggatacga atagttcatc taggaattta
    81541 acgatcagga ggaaaagata tattgaaaaa gaggaggatc gtgctcattt taagcagtct
    81601 cttagtgact aatatctttc cgatcatagg gtactctttg gaattgaatc agttggagca
    81661 tggaaataga agagacgaag aaagcaaact cacttcgaca ttcgacagtt taatagaatc
    81721 caaccagaca caagaaagca gtgaggattt aagtatttcg agtagtggag agaccactga
    81781 caacgtagaa gctgagggtt cggacaaaca aggactagaa gatgcaccaa tttctgcggt
    81841 tgagctgcct gacgatccca atattatttc tatcgataaa atttttcaaa cacctatcgg
    81901 tactagcacg tccatattgg aaaatgggaa gttactgcag ttgaacccag cagaaaggtc
    81961 tcaaagagga gctatttggt caaataagaa gattagttta ctctcggatt ttacatttaa
    82021 atcttattta tacttaggaa atcaacgaga tagagcggga gatggcatga cctttacatt
    82081 gactggcgat cctagaatgg ctagtaatcc cagtcaagtt attggatcgc caggtatggg
    82141 aattggctca tattctactc gttctggcca accttacatt gcgaatgcgc tctcgattga
    82201 gtttgatacg tataaaaata gtggttcttc tgatcgaatg gatcgagaga taactgctga
    82261 taatagaggg catggacatg tcgcttttgt cacgcctaaa ccaaataata ataattattc
    82321 tggagagcat actggcgtga cggtagctcc tacatttctt tctaatggca catggcgctt
    82381 gttaataatt aaatgggacg cggagcaaag aagtcttact tatgatttgg aaggtgtcgg
    82441 tcactcttct cggattatac ctgatctcat taggcagttt ggttctacag aagtaaattg
    82501 ggggtttact tcttcaacag gtactttttt tcaagaaaat gctgtcgctg tcacgcgact
    82561 tccatcgaat gtcacatcaa cagctgatgt aaaagtcaac gatagtgatt atggggccat
    82621 cgctgaagct ggaggaaacg ataagataac tatcagaaat acattgaagg tcgaggggga
    82681 ttttcttgaa tataagaaaa tgcagactag tatcgacctc ccacaagaat taactattcc
    82741 cgagcatatc ttgatcaatg gaaatcaaat tgatgccaaa gatatcttga taaccggaaa
    82801 tcgagtcacg ctaaatctga cagattattt tattgctgga gatacgttaa taatcgaatt
    82861 ggagacaact ttgcaggaag taattcctga aaaagtactc actatgcatt ttgaatacct
    82921 tgaaaacggg aatttgattg agcaatcgaa tgaaataaac ctaaagatcg caaagctgaa
    82981 ggagatagat atccatgttt attataaaga taaagacagt cagattgata ttgctgaaat
    83041 gaaaacaatc actgggaaaa taggagagaa gtataaagaa actcctattg atattgaagg
    83101 gtatgttttt gactcggatt cagcgaatac agaaggcatc ttctccgaaa atacagagga
    83161 tatctatttt tattacagaa aaggcaaact ttatctctca actgctcctc aatatgtcaa
    83221 ttttggaaaa cataaaatat ccagtagacc attaagtgaa ttcggacagt tttcaggtgg
    83281 gttgaaaatt atagatgaac gggcttttgg aagttggaaa ttacaattga aacaagagaa
    83341 agttcttaca aatggagatt ttgagcttcc agaagctctt tcctttgtta cctctgaaaa
    83401 tacaacggtt atagggacat ccgctgttac gattttcgaa agtgatcaaa agggtgaaag
    83461 cgatttgtcc tctcttttag attctacagc tcatcgtgga atcagaatag atattcctgt
    83521 agaaaaccaa agaatcggaa cctttgaggg gaaactatct tggatacttg cagatgtccc
    83581 aggaaattaa caggaagaga agaatataac aaaattattg agtttcaaga agggcacagg
    83641 taccataggc tcttgtgtcc cacagagaca agattttgtt atagtcttct cttacatatg
    83701 attaaaggag cgattttctt gagaccaaaa caacaattat ttataacact cctagttatt
    83761 ttaggggcac tttttaacaa tatatcagtg tcagctagtg catttaattt ttcagtgacg
    83821 ccgataactt cagagaatca aatcgacaag agaaaaactt acttcgatct tcaacttgat
    83881 ccggatcagg aagtagaagt aaaagcggaa ttgagaaatg atacagaaaa agaagtgaaa
    83941 atcgatattt ctgtgaatag cgcaaccacc aattcaaatg tgatggttga atacggaaaa
    84001 aacgagattg aaaaagacat gagcctgatc tttgatctgg tagattatgt gagctatcca
    84061 cagatagtga cgctaaaacc taaaagtgtc caaaccgttg cttttcatgt caggatgccg
    84121 aatgagcgat ttgatggtgt attggctggt gggatcacat tccaagaaat ccagacggaa
    84181 aaggaccaaa cagaaactaa ggatcaaagc ttatcgattg agaatgaata cacctatatt
    84241 attgctttgt tgatgcaaca gacactgaac gaagttgctc cgaaccttac tcttcatgaa
    84301 gttaaaccag atcaaatcaa tgcaagaaat gtcatcttag caaacgttca aaatgatcaa
    84361 aaaacctata tcaatcaagt agttattgaa acaaaaatta caaaaaaagg acattctgaa
    84421 gttttatatc aagaggaaaa agaaggattg cagattgcgc cgaatacaaa tttttctttt
    84481 ccaactgctt taaatggtca accgctaacc ccaggtgaat atcaccttac aatgactgtt
    84541 ttaggaaatg aaaatgaaaa tggaaaattt tcgagaaaaa aaggaaatac tacgatcaac
    84601 tataccaatc aatgggtatt tgaaaaagat tttacaatag acggaaaagt agccaaggaa
    84661 ttgaacacga cggatgttac gattaaaaaa gacaataatt ggatttatat cttagtagct
    84721 tcacttttct tattgtttat tttattatgc atacttttgt ttgttttgag aaaaaaagaa
    84781 gagaaagaaa agtaaggtta agataacaaa tagtaaattt ttattattgt aggatggttg
    84841 ggctcttttt ataacaatat aaaatatacc attttattaa taaaaatgca tactagtaaa
    84901 tgatataatt ctaataacag gtttgatcgc gagaaaggcc aaataaaacg ctctccaaaa
    84961 tgttaaaaaa aagacaggac gatgtatatt atacaaacaa gaatcgctga caacagtgac
    85021 tcggatccag gaaatcagtt ttatccccag ctagttggtg aatgcatgga aagtaatata
    85081 cgtagaaaga gctgatgact aatgaattat gagttttttt taagcaaaga agatcacaga
    85141 agttattcat tacttaaata tttagaagca agctcaaatt tatcagagtc aatatcgaat
    85201 gttcaagaag agttgtcgct atcgacattt ctcttgaaaa aaacgatcga taagctgaaa
    85261 catgatttac aaaagttcga tctagagaaa aatttgcgag taaccgtcag tgaattggat
    85321 atatgtctgg aaattaatgg aaaatgttct agcaaagctc tgttatctcg ttatataacg
    85381 gattctttat ctatgaaaat ggtattggct ttctttcagg aaaaatatat ctcagtagaa
    85441 aattttgcta aacagcatca cgtgagttat tctgtggctt ataaagtatt acaaagacta
    85501 aaaagaaatc taaaaaaata tcaaattttt tttgaaaaga gaaagttg
//
LOCUS       DAFEEZ010000004        82798 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000004
VERSION     DAFEEZ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 82798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.004"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            212..604
                     /locus_tag="LP245_000288"
     CDS             212..604
                     /locus_tag="LP245_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1518235.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="LP245_000289"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="LP245_000289"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBL1518236.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="LP245_000290"
     CDS             3165..4775
                     /locus_tag="LP245_000290"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBL1518237.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="LP245_000291"
     CDS             5067..5936
                     /locus_tag="LP245_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBL1518238.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="LP245_000292"
     CDS             6101..7372
                     /locus_tag="LP245_000292"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBL1518239.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="LP245_000293"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="LP245_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBL1518240.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="LP245_000294"
     CDS             8763..9026
                     /locus_tag="LP245_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBL1518241.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="LP245_000295"
     CDS             9471..9920
                     /locus_tag="LP245_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1518242.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="LP245_000296"
     CDS             9977..11395
                     /locus_tag="LP245_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1518243.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="LP245_000297"
     CDS             11395..12255
                     /locus_tag="LP245_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBL1518244.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13203
                     /locus_tag="LP245_000298"
                     /pseudo
     CDS             12429..13203
                     /locus_tag="LP245_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
     gene            13350..13715
                     /locus_tag="LP245_000299"
     CDS             13350..13715
                     /locus_tag="LP245_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBL1518245.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13863..15071)
                     /locus_tag="LP245_000300"
     CDS             complement(13863..15071)
                     /locus_tag="LP245_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1518246.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15090..15368)
                     /locus_tag="LP245_000301"
     CDS             complement(15090..15368)
                     /locus_tag="LP245_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518247.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15522..16217
                     /locus_tag="LP245_000302"
     CDS             15522..16217
                     /locus_tag="LP245_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL1518248.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16659..17456)
                     /locus_tag="LP245_000303"
     CDS             complement(16659..17456)
                     /locus_tag="LP245_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBL1518249.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17453..18637)
                     /locus_tag="LP245_000304"
     CDS             complement(17453..18637)
                     /locus_tag="LP245_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBL1518250.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18662..19909)
                     /locus_tag="LP245_000305"
     CDS             complement(18662..19909)
                     /locus_tag="LP245_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBL1518251.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20124..21869
                     /gene="dnaX"
                     /locus_tag="LP245_000306"
     CDS             20124..21869
                     /gene="dnaX"
                     /locus_tag="LP245_000306"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBL1518252.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21889..22203
                     /locus_tag="LP245_000307"
     CDS             21889..22203
                     /locus_tag="LP245_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBL1518253.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22228..22824
                     /gene="recR"
                     /locus_tag="LP245_000308"
     CDS             22228..22824
                     /gene="recR"
                     /locus_tag="LP245_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBL1518254.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22888..23532
                     /locus_tag="LP245_000309"
     CDS             22888..23532
                     /locus_tag="LP245_000309"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBL1518255.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23547..23876
                     /locus_tag="LP245_000310"
     CDS             23547..23876
                     /locus_tag="LP245_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBL1518256.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23890..24828
                     /gene="holB"
                     /locus_tag="LP245_000311"
     CDS             23890..24828
                     /gene="holB"
                     /locus_tag="LP245_000311"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBL1518257.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24864..25688
                     /locus_tag="LP245_000312"
     CDS             24864..25688
                     /locus_tag="LP245_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBL1518258.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25681..26028
                     /locus_tag="LP245_000313"
     CDS             25681..26028
                     /locus_tag="LP245_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBL1518259.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26097..26969
                     /gene="rsmI"
                     /locus_tag="LP245_000314"
     CDS             26097..26969
                     /gene="rsmI"
                     /locus_tag="LP245_000314"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBL1518260.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27078..28199
                     /gene="dinB"
                     /locus_tag="LP245_000315"
     CDS             27078..28199
                     /gene="dinB"
                     /locus_tag="LP245_000315"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBL1518261.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28253..28855)
                     /gene="nrdG"
                     /locus_tag="LP245_000316"
     CDS             complement(28253..28855)
                     /gene="nrdG"
                     /locus_tag="LP245_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBL1518262.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29170..31359)
                     /gene="nrdD"
                     /locus_tag="LP245_000317"
     CDS             complement(29170..31359)
                     /gene="nrdD"
                     /locus_tag="LP245_000317"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBL1518263.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31658..32452
                     /locus_tag="LP245_000318"
     CDS             31658..32452
                     /locus_tag="LP245_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518264.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32442..34484
                     /locus_tag="LP245_000319"
     CDS             32442..34484
                     /locus_tag="LP245_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518265.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34765..34914
                     /locus_tag="LP245_000320"
     CDS             34765..34914
                     /locus_tag="LP245_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBL1518266.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34925..36439
                     /gene="dltA"
                     /locus_tag="LP245_000321"
     CDS             34925..36439
                     /gene="dltA"
                     /locus_tag="LP245_000321"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBL1518267.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36436..37641
                     /gene="dltB"
                     /locus_tag="LP245_000322"
     CDS             36436..37641
                     /gene="dltB"
                     /locus_tag="LP245_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBL1518268.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37686..37919
                     /gene="dltC"
                     /locus_tag="LP245_000323"
     CDS             37686..37919
                     /gene="dltC"
                     /locus_tag="LP245_000323"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBL1518269.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37922..39190
                     /gene="dltD"
                     /locus_tag="LP245_000324"
     CDS             37922..39190
                     /gene="dltD"
                     /locus_tag="LP245_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBL1518270.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39331..40413
                     /locus_tag="LP245_000325"
     CDS             39331..40413
                     /locus_tag="LP245_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBL1518271.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40413..41216
                     /locus_tag="LP245_000326"
     CDS             40413..41216
                     /locus_tag="LP245_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBL1518272.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFVFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41286..42026
                     /locus_tag="LP245_000327"
     CDS             41286..42026
                     /locus_tag="LP245_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL1518273.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42037..43041
                     /locus_tag="LP245_000328"
     CDS             42037..43041
                     /locus_tag="LP245_000328"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBL1518274.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43086..44930)
                     /locus_tag="LP245_000329"
     CDS             complement(43086..44930)
                     /locus_tag="LP245_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518275.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45142..45660
                     /locus_tag="LP245_000330"
     CDS             45142..45660
                     /locus_tag="LP245_000330"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL1518276.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45788..46471
                     /locus_tag="LP245_000331"
     CDS             45788..46471
                     /locus_tag="LP245_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBL1518277.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46780..46853
                     /locus_tag="LP245_000332"
     tRNA            46780..46853
                     /locus_tag="LP245_000332"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46814..46816,aa:Arg,seq:tct)
     gene            47012..47371
                     /locus_tag="LP245_000333"
     CDS             47012..47371
                     /locus_tag="LP245_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBL1518278.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47494..49125
                     /locus_tag="LP245_000334"
     CDS             47494..49125
                     /locus_tag="LP245_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBL1518279.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49187..49828)
                     /locus_tag="LP245_000335"
     CDS             complement(49187..49828)
                     /locus_tag="LP245_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBL1518280.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    50014..50090
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            50110..50418
                     /gene="rplU"
                     /locus_tag="LP245_000336"
     CDS             50110..50418
                     /gene="rplU"
                     /locus_tag="LP245_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBL1518281.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50445..50789
                     /locus_tag="LP245_000337"
     CDS             50445..50789
                     /locus_tag="LP245_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBL1518282.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50802..51095
                     /gene="rpmA"
                     /locus_tag="LP245_000338"
     CDS             50802..51095
                     /gene="rpmA"
                     /locus_tag="LP245_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBL1518283.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            complement(51188..52336)
                     /locus_tag="LP245_000339"
     CDS             complement(51188..52336)
                     /locus_tag="LP245_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1518284.1"
                     /translation="MAMIKQYKKKNGEKAWYFKTYLGIDPLTGKKKYTTKRGFRTQKE
                     AKTALSRLELELQKTGMPTSTNTTFKEAAELWLESYKKTVKESSYSRTKIIFNKHIYP
                     KFGNIKLSKINTAYCQKVVNDWSEKGTSKQYPLFINYMNKVFKYAINIGLTSDNPTLN
                     LLIPKPQIKTEKKLKLYTKEQLELFLNEVSQEQNPYFKNRDYTLFRLLAFSGCRIGEI
                     LALTWDNINFKTNEMAIKKTVARSDKYYISETPKTKKSNRIIYLDEKTIKQLKFWKLE
                     QRKYLFQLGFTKANYLFTNDENNFTINQSVAERYNIYRERAGLPYIGLHGFRHTHASM
                     LYEAGADHKEVQERMGHANIKTTMDTYTHITNSKKEETTQKLTNYINF"
     gene            complement(52348..52659)
                     /locus_tag="LP245_000340"
     CDS             complement(52348..52659)
                     /locus_tag="LP245_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518285.1"
                     /translation="MIYTEFKEWLEKSTTGYETFIIKATNYQIEKNKNRPQKKRWDDK
                     KIDKAVLEMWKQVVTNLYQTIRKEKGVPLINGKEIWLEFIEEQGLIEFFNDSMAELEF
                     E"
     gene            complement(52712..53107)
                     /locus_tag="LP245_000341"
     CDS             complement(52712..53107)
                     /locus_tag="LP245_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL1518286.1"
                     /translation="MIINELGVKVEERENLDADGHYVACMNTIVIKANLSKYRRQRTL
                     LHELGHASKHHDNYFLYNLAFSLHSKMEYEADRFMIEKLLDRYIAKSELEPHNINYMK
                     FIEDNNLSVRFEPLVKELLKARIYCYAAL"
     gene            complement(53143..53487)
                     /locus_tag="LP245_000342"
     CDS             complement(53143..53487)
                     /locus_tag="LP245_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1518287.1"
                     /translation="MLFERVKELCKKRGISISELENRIGFGKNSIYKWKTQSPKIETL
                     QKVADYFHVSTDYLLGRTDDPNAGVAPEERKLTVEEALASVMSSDGKPLTDNDREILS
                     AMIEAYLEKKDN"
     gene            53788..54009
                     /locus_tag="LP245_000343"
     CDS             53788..54009
                     /locus_tag="LP245_000343"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518288.1"
                     /translation="MKQNKKTPSAKGALITLNFKDQKFSAVVDEIHPQEHQKNSFATD
                     EKKTQKRSEKVLRIIQFLLEKIRHFGSLF"
     gene            54136..54912
                     /locus_tag="LP245_000344"
     CDS             54136..54912
                     /locus_tag="LP245_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBL1518289.1"
                     /translation="MNTPQIFNFEQHEVRTVTIHDEPFFVGKDVAKVLGYQNGSRDIN
                     RHVDVEDRQNYQNGTFESPRGLTIINESGLYSLILGSKQPNAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATKLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMRQGYTKSHTTEIPK
                     SDGGTKVVMNTKWTQKGRLFIYESLKKEGYIPEIDLLEEE"
     gene            54915..55103
                     /locus_tag="LP245_000345"
     CDS             54915..55103
                     /locus_tag="LP245_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1518290.1"
                     /translation="MSQEFILKVRIQLAKYGKSQNWLADTIGISRPYMSDIMNGRRKP
                     DKQIKPIEAALAELEKEK"
     gene            55105..55389
                     /locus_tag="LP245_000346"
     CDS             55105..55389
                     /locus_tag="LP245_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518291.1"
                     /translation="MQITIPDNLVVSELTTQITNAVLNSLDERLHLMNKSVELPPYPN
                     KSEVKKVLGIGDDKLTHWISLGLKTQQWSKLDIRIERSELQRFLKENFEF"
     gene            55410..55598
                     /locus_tag="LP245_000347"
     CDS             55410..55598
                     /locus_tag="LP245_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518292.1"
                     /translation="MSYTLQQEHQILGLIKQRRKQLQDDRAALRKSDELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            55924..56163
                     /locus_tag="LP245_000348"
     CDS             55924..56163
                     /locus_tag="LP245_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518293.1"
                     /translation="MENELSTLDQYLADPDWGKSNLQLVANKYEKSIDEAIVALTDAA
                     SITADDSKWTKRDLGILKRGVNWLEDQYREETKEK"
     gene            56169..56855
                     /locus_tag="LP245_000349"
     CDS             56169..56855
                     /locus_tag="LP245_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518294.1"
                     /translation="MFKPLIDSYSAVLKKFKGNDIGATINEEVNIERLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGREISLK
                     DESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            56858..57688
                     /locus_tag="LP245_000350"
     CDS             56858..57688
                     /locus_tag="LP245_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HBL1518295.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            57705..58556
                     /locus_tag="LP245_000351"
     CDS             57705..58556
                     /locus_tag="LP245_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1518296.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALEKAKSYTNEVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNTELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            58553..58912
                     /locus_tag="LP245_000352"
     CDS             58553..58912
                     /locus_tag="LP245_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBL1518297.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQA
                     PLILAKKYRNTFKEERF"
     gene            58927..59088
                     /locus_tag="LP245_000353"
     CDS             58927..59088
                     /locus_tag="LP245_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBL1518298.1"
                     /translation="MTTEEVIQMRIRNIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            59085..59390
                     /locus_tag="LP245_000354"
     CDS             59085..59390
                     /locus_tag="LP245_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518299.1"
                     /translation="MSVDKKATMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RKTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            59390..59746
                     /locus_tag="LP245_000355"
     CDS             59390..59746
                     /locus_tag="LP245_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBL1518300.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            59733..59951
                     /locus_tag="LP245_000356"
     CDS             59733..59951
                     /locus_tag="LP245_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518301.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            59972..60061
                     /locus_tag="LP245_000357"
                     /pseudo
     CDS             59972..60061
                     /locus_tag="LP245_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293000.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            60136..60603
                     /locus_tag="LP245_000358"
     CDS             60136..60603
                     /locus_tag="LP245_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HBL1518302.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQPR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            60878..61114
                     /locus_tag="LP245_000359"
     CDS             60878..61114
                     /locus_tag="LP245_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518303.1"
                     /translation="MYWRVYKMKIASEKIDQLTILVNQRIEDIIKEFEGEKIKNIKLT
                     LMDHKFELNSTKRKIVELIEEEIALQINEQQLAN"
     gene            61138..61479
                     /locus_tag="LP245_000360"
     CDS             61138..61479
                     /locus_tag="LP245_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518304.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDSRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(61472..61663)
                     /locus_tag="LP245_000361"
     CDS             complement(61472..61663)
                     /locus_tag="LP245_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HBL1518305.1"
                     /translation="MVKNLYFVIREATNGQYYFVIKSNNNEVVATSETYLTKYSAEQT
                     INSIKNGITKDSQVIDMTK"
     gene            61873..62520
                     /locus_tag="LP245_000362"
     CDS             61873..62520
                     /locus_tag="LP245_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518306.1"
                     /translation="MVGVVKFLGFTFDGYGTLGEWVGIILIVITIQQTSKYYWYSNSS
                     KIVSRITEGITKKDITVVGKYGFTITLLNEGKSETAIKFCGIIGKYNIFQRFIRKHWY
                     KYIYKYPVVKKLIEKYVDHEISYLNPTDLINQEFQNIGYLEKGLKIPIVNESLVTAMV
                     ANIKNSKKLEKRYKKCKKLKFSFLFLEYNGKEYYQDIYVLRGSNLYKDIKNKISV"
     gene            62780..63124
                     /locus_tag="LP245_000363"
     CDS             62780..63124
                     /locus_tag="LP245_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL1518307.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            63129..63410
                     /locus_tag="LP245_000364"
     CDS             63129..63410
                     /locus_tag="LP245_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518308.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            63513..63827
                     /locus_tag="LP245_000365"
     CDS             63513..63827
                     /locus_tag="LP245_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBL1518309.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            63805..65499
                     /locus_tag="LP245_000366"
     CDS             63805..65499
                     /locus_tag="LP245_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBL1518310.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            65519..66697
                     /locus_tag="LP245_000367"
     CDS             65519..66697
                     /locus_tag="LP245_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL1518311.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            66660..67346
                     /locus_tag="LP245_000368"
     CDS             66660..67346
                     /locus_tag="LP245_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBL1518312.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            67346..68507
                     /locus_tag="LP245_000369"
                     /pseudo
     CDS             67346..68507
                     /locus_tag="LP245_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
     gene            68517..69392
                     /locus_tag="LP245_000370"
     CDS             68517..69392
                     /locus_tag="LP245_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518313.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            69389..69700
                     /locus_tag="LP245_000371"
     CDS             69389..69700
                     /locus_tag="LP245_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518314.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            69690..70043
                     /locus_tag="LP245_000372"
     CDS             69690..70043
                     /locus_tag="LP245_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBL1518315.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            70033..70434
                     /locus_tag="LP245_000373"
     CDS             70033..70434
                     /locus_tag="LP245_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518316.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            70427..70831
                     /locus_tag="LP245_000374"
     CDS             70427..70831
                     /locus_tag="LP245_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518317.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            70843..71448
                     /locus_tag="LP245_000375"
     CDS             70843..71448
                     /locus_tag="LP245_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1518318.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            71468..71830
                     /locus_tag="LP245_000376"
     CDS             71468..71830
                     /locus_tag="LP245_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518319.1"
                     /translation="MIEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            71833..72015
                     /locus_tag="LP245_000377"
     CDS             71833..72015
                     /locus_tag="LP245_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518320.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            72032..75451
                     /locus_tag="LP245_000378"
     CDS             72032..75451
                     /locus_tag="LP245_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBL1518321.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITVIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWVSIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSIFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLCVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            75502..76239
                     /locus_tag="LP245_000379"
     CDS             75502..76239
                     /locus_tag="LP245_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1518322.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINYFNCTGLSKIQIYRNGLR"
     gene            76249..78540
                     /locus_tag="LP245_000380"
     CDS             76249..78540
                     /locus_tag="LP245_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1518323.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITASQAWQNAKTLAKPVIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            78564..80654
                     /locus_tag="LP245_000381"
     CDS             78564..80654
                     /locus_tag="LP245_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518324.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGGYDYSGKPNLMSKLKSSDFN
                     VGYHGSLTLDNEKLHFTSDGTGSIIMFTRINTPQLTSGKTYTLSAKVRFDEGTTGAID
                     KLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYMSISFVD
                     RDKINGGFKLYDIKIEEGSTATPYQPNLLDAPYYLSKVALGENLIKPESQQPVTNSNY
                     LINTYNIKPMVKGKKYTITLEGTKPATQVFRPFFTRATGDAWEVGDLQPVEGLTNVWS
                     KTFTAADDSHPTTPQVQIYQVPSTSVGQCTIKWLKLEEGNTRTPNISEYKYRGTGMRD
                     SNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASINEVDTT
                     AKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFV
                     ALNGKRSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNS
                     SYGSDYTFAITYTI"
     gene            80671..80820
                     /locus_tag="LP245_000382"
     CDS             80671..80820
                     /locus_tag="LP245_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518325.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            80817..81263
                     /locus_tag="LP245_000383"
     CDS             80817..81263
                     /locus_tag="LP245_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518326.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            81265..81402
                     /locus_tag="LP245_000384"
     CDS             81265..81402
                     /locus_tag="LP245_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBL1518327.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            81440..81733
                     /locus_tag="LP245_000385"
     CDS             81440..81733
                     /locus_tag="LP245_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518328.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            81730..81954
                     /locus_tag="LP245_000386"
     CDS             81730..81954
                     /locus_tag="LP245_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBL1518329.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            81951..>82798
                     /locus_tag="LP245_000387"
     CDS             81951..>82798
                     /locus_tag="LP245_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL1518330.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDV"
BASE COUNT        27663 a        13636 c        17082 g        24417 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aaagctttta gaaaacaatc agaccggctt gccgttttag ttacacagca aaaaattgca
    13081 cataaattca tgcatcaagc cattgctttt catgaaatcg attatctggt gacaagtaaa
    13141 gaactgacaa aagaacagta tgcgaaagta aaggaacacc atatcgaatg tctgtacgga
    13201 taaattatta cgtgaatgtt ctaagtggct tcctcatttt tagataggac cttatctttg
    13261 ctcgcttttc tcagccgatg gtataataat gaaaaggtta tcttgttaga taatcttact
    13321 tttttatcca ggagaaagga gtgcagaaaa tgaaacatgt gaaggcgttg gtagtgaagg
    13381 caatcatgat ctgggcgatt ctgtgggtcg tgctgacagg tttatacggt gttagcttta
    13441 tggattcaac gattgttggg gtaattattg tagtcatgat ctatgtgcta ggggatctgt
    13501 tgatcttacg taaagtaggg aacatcgcag cgacgatcgc agatgctggt tcagctgcag
    13561 ttatcttgtg gctctatcta tattttatga atgatacagt cgatatttgg atgaaagtat
    13621 tgattcctgc tctattgatc ggtgtggcag aatggttctt ccacaagtgg ttgctaagtc
    13681 aaggcatcgt accagatgaa cggaaaatgg aataaatcaa cagttaaact attcttatcg
    13741 ataaatgaaa gctttaaaaa taaatagatg tttaattaag aataatcata aactattttt
    13801 actcaaaaaa ccgctcagat tattttcaga tctgaacggt tttttttatc tattcatcaa
    13861 gatcaaattt catttttcaa tgattcaatc aattcgccct ctgcttcatg actatgtttt
    13921 cggccattaa caagatagag tgctgtacat atcaatggaa tgactccggc aatcacatac
    13981 aatcctctaa atgaagtaag agattttagc atccccatca aataaggacc aacgcctaag
    14041 cctaggtcta aaccaataaa gtaggtagat aaagcaatac tgattcgatg ttcgcggacg
    14101 atttttaaac aaacagcctg tccatttgac ataaacgtac cataacctag gccgactaat
    14161 gctccagaga taagcaatgt cacactattc gtcgttacac tcagtaaaaa taatcctgct
    14221 gttaagaata aatagctagg atacatcacg tattgttctc ctttgacatc gaaaatcctt
    14281 ccagtcaatg gacgtgtaaa tgtgatgacc aaagcatata cgacgaagaa aaatgaccca
    14341 gcagcaacta agtggattac ttttgtataa gaagataaaa atgataaaac acttgaataa
    14401 gaaagaccca tcaaaaaggc aattcctgta atgaaaagtg ctttcttttc aataaaacta
    14461 ttgatattcc atgagcgaag agatattttt tgttcttcag ataatggaat attttttaca
    14521 ggaaagacaa ggcaggcaat cgtaacaaag aagaccagta caattgaaaa ccagataatg
    14581 aaacgaaaat cagtcatatt cagcaaaatc attcctaaaa atggcccaac agcggcagct
    14641 aaactagtac ttaatccata ataattgatg ccttcccctt ttttagatgc agggatatat
    14701 gcagtaacga tagcatttgt agctgtagaa actgtaccgt agccgaatcc attcaagaat
    14761 cgaactaaat acaatgcccc gatagttggc gtataaagat atgctaatgt tgaaaggaga
    14821 tagaagatcg cgccgcctct taaggtaaac ttccgaccaa atagttctaa ctgtttcccc
    14881 atgaataagc gtgccagcaa tgttccgatg atatagatcc cagaagcaaa acctgcttgg
    14941 ctcaagctgg cgtgtaaggt gtcttgcgca atgactgcca tgatgaccat caacagataa
    15001 taaatcaggt agacaataaa attgatcaat gtgattccaa taaaatattt attaaataat
    15061 ttcttttcca tgtatgttat acattcccct taagctgaat atgcttttaa tttttgtatt
    15121 tgaacttcta catcgtgata attggatgga tagcgatcaa caagttggcg aataaataaa
    15181 tctcttgtag acataaacag atttaaaaat tcttcgcatt cgtttgttgg attctcatcc
    15241 actgctttga tcaattcgat cgagttttga tacgcatcat ttaaaaagac taaagaagct
    15301 ttcatatcaa atcttgtttg atatgctgtt tctaatcgat taatgattgt gttcatccag
    15361 taattcatgt tttttccctc tattcttaaa aaattttact tctgcagtat aacgaataaa
    15421 aaaaaggaaa aaaatcgcat aagtgatgga aaaaggtact taacaaatgt taatatcatt
    15481 agtaaaatac ctttggactt taaaaagttt taaagtactg tatgatcttt ttagatgaaa
    15541 gtttggatgg gggagcatca ttggatagta gagtcttaaa ggaatatttg gataaaaatg
    15601 attttccgat tatacgcaaa ggatatcata aatatttgac attcgaaggg atggaagatt
    15661 cccatacgta tatcttgaaa gagggaacgg taaaagcaag tgttatttca aatgatggga
    15721 gagaatttaa ccttcgctat atcaaagatc ttgaaatcgt ctctctttta aaagacgaat
    15781 attcacaatt catcgattcg ccgtataata ttcgagttga atcagaatat gcagagtttt
    15841 atcgaatcaa tcgtgtgcgc ttttggcaaa atatcaacca agacccaaag ctacaacact
    15901 atgtaaaaga gtattaccgc tatcgtctgc tttattcgat gaaaaaaatg cagcaaatgc
    15961 tattaaacgg aaagctggga gctgtttgta cgcaacttta cgaattatat gatttattcg
    16021 gtgtgcggac agaagaaggg atgctgatcg atttttcgat cacgaatgaa gaaatcgcca
    16081 aattttgtgg catctcaact gctagcagtg taaacagaat tttaaaacaa ctgaaaaaag
    16141 atggtattat caccgttaaa gaccatcata tcgttatttt gaatatggac ttgttagaag
    16201 acaatattat cttttgatga acaaagaggt tgtgaaatca gcgttttgac ctgagtatta
    16261 gagaaacaaa cggaaaaata gttcctcata ttttgccgtt ttttgagcta ataccgaggg
    16321 tcagctgatt gaacaccgtt taccaagagg ttgtgagcct gccgtttaac tctgagtcac
    16381 aaggaacaat ttcaaaaaac agcttttcat gtttgatgaa tattgtgact tgtgaccgag
    16441 gagttggtag gagaacaccg tttaccaaga ggttgtgaaa aagctgttct gcatcaagta
    16501 ataagaagag ccaagtaaaa acagtctctt atgtttttaa cttggctgga cttatcaccg
    16561 tagatgtaag cttttgaacg ccgtttattt gcaacaaaag gggctgtgac acgatttttg
    16621 tcacagccct ttttttgcga acattcattt agcaattttt agaaacttct gccgccaccg
    16681 ccaaaagtcc cgccaccgct agaatgggta gtacttccgc caccgccgct tccaggaggt
    16741 gggcttttgg ggattcttct tgtcgtgaca aaagaatttg tcagacgatc ggttttttca
    16801 gttaatttga tactggattt ttctcggaat ggatatttgt agatgcctga tttcaattga
    16861 taacgcgaaa cagtcacaaa ataaaagaca agactaagga taagagccaa aacaacagca
    16921 atgatgattt ctactgtcgt caaaacctta tagcgtgtaa ttttgccagt ttcttcgtct
    16981 acacgataat gtcctcctgg aactccgtct tccacatatg ttgctgattt agacaggtaa
    17041 gcttttgcag cattgtaata ggcagcattt gtcatctgat cataaacatc atctaagatc
    17101 gaatcgattc tgctatcagt caaataatcg atcatattac cagaagtcga aatgtagatt
    17161 tcacgctgtc ccatatctaa tagcaatact gagccatttt gatcatttcc gactgcgtct
    17221 cttaagtaat tatcagcaaa gtctcttggt tcttctgaat tagatgtagt cgttacgatc
    17281 aagactcgtc ctttgatttt ttcattcagc ttttctgcct gttgttccaa agattggatt
    17341 tgatctgttg tgaataaccc agcctcatca tttaccgtag ctgtatctgc atgagtagcc
    17401 accggccagc caacacttac tagcaaaaga aagaataaaa aaaatttttt catcatatca
    17461 agtaacctcc gatcagaaag aggatcgcta gcccagcgaa aatcccaaga gcggtcagtc
    17521 ccaatttttt ctggctgatc ggcaggacac cgctgacctt tcctgtttgt ccattcattg
    17581 cgtagtagta gactttttta cttgagtcat tgcttcgata agtaacaagc cataccggca
    17641 gtaatacgta attatttact tcgtttgtga ttgaagcaga agttcgcaca ccggtcaatg
    17701 ttgtatatcc atttgcggta tcttttaaca gcttctctga atagtctttt aattcagatt
    17761 gaatctgtga tttgattgcc tcatattcga tatctctttt ttctgcttgg aacccggcta
    17821 aatactggct tttaaaatca attgctttat ctaacgggaa aggttgcacg ccttcgacca
    17881 tcttttgttg cgtatttttt gataaggcat tttttactag ttctttaaaa gaaagcttgc
    17941 ctgctcttga aacagcaaat tgcttcgttt ctgtgtattc gatgtcacct atccgccata
    18001 tgcggataac tgtaccattc gcctgcatgg caccatctac ttcagcatct gtagcccaat
    18061 aagggaaata cacacctgtc aacttatcga tttgatcctt attgaaaaaa gctttgggaa
    18121 caaaccattt tttcttggtc caagcgagaa atctgttgat tgcttcttct ttctcgacag
    18181 caaaaggaag tactttattt ggcaagaatt ctccgcttaa acgtcccgat agtacgacgg
    18241 gattatggca gtagtaacaa taagtcgcag cagttgtcgc atcagtcacg atctctgcac
    18301 cacagttggg acaaagaaaa agatctatcg ctgcggtatt atctgcagat tcgtccgctg
    18361 tatctgaaaa accgcctgcc tcgtcaaccg ctttgcgctc ggcttcattc atatcggcaa
    18421 gctgttcttg ggctgtaaaa gtaaaatctt cggtaggtga aggttcttct ttgctttctt
    18481 cgccagccat acgcgcttct ttttgctttt gctcatattg gctgacttct tcttctgtat
    18541 agatattcag gcagtattcg caatgaaatt tttggtcttt gggatcaaaa gtcaacggac
    18601 cgccgcaatt aggacattta tgtgtaagaa catccatcag ctgcacacct ttctaaataa
    18661 attaattaac ggggattcct ttaaacggtt taccacagtt tggacagaat ttagggatgc
    18721 cgttggaaag atccacgatc tcattgcatt cactgcatcg catttgtagc ttaggctgaa
    18781 cgttttctac aggtttggca gctccgcagt tggaacagaa ttttccggaa ttttctgtcc
    18841 cgcaaactgg acatgtccaa gtatccgcat ttccttgtgc agtttgttga ttttgttttt
    18901 ctgcttgttg tttgatttgt tcttggttat tttgagctgc ttgagaaaga taagaaccat
    18961 ttgcattcat tcccatacct acacccataa agccggtcat tgctcctgct tcattttttc
    19021 cggctgcttc cataccacgt gcaatggaac cttgcacgta tccttcacgt acgctaggat
    19081 cacctagcat cgccccttcg ttacgcatat tgatcagttt cacagaatca tcggtgtaag
    19141 aaatgctggc tacagccaca gaaacaatct ccatcccacg taattcacgc caagaatcat
    19201 ccaatgcagt atccatgtat ttgcttaatt ccaaactctt agatggtaca taagaaatcc
    19261 gttgaccatc tgcagacatc tgattgattg ctgattgtag cgctgttagg aattcagcta
    19321 aatactgctc attgatatca ttgatttcca cttgtgtttt gtttttaggg attgcgtttg
    19381 tataaaataa aatcgggtca acgacatgaa tagaataagt gccatgtgcc cgtaagaata
    19441 attctgcgtt atagaaattg tcaaagtagt tcaacggcgc gcttgtaccg aatttgattc
    19501 cctttatttc ttggagattg atataaaaaa cttgttgttt ctgcggtgtg acgccgccaa
    19561 atttgaatcg gtcaaaagtt tcagcaattg cttctttcag tgttccattg aacatggaag
    19621 gagctgcgtc atttttaatg gtgtaataac cttcctcagc ggtataatcg atgatttttc
    19681 caccatcgac caaaagcatc atcatgtttg gatagacatg gacgactgtt ccgtctgtta
    19741 aaacatcttc tgttccttta cgattggagc cacgtttgtc atctttgcgg actttgacac
    19801 cttttgtcat gaccgttgta tcactcatat tgtctggttc gatgacttct agccattgat
    19861 ctgccagacc gccgccaacc atacttgttg ctgctttgat aagacccata aaaaattcct
    19921 cctctgattc agctagtgcc aaacaattat tgtttattta ttataccata ggaagatgtg
    19981 aaacttctcg gactagagac ggaattgaaa tggaaaattg cgtattgttt aaatacctga
    20041 aaaagccgag aaggatagta gtttttttac ctaatatcac gtataataag agatagtgaa
    20101 tttttaaaaa aagggggatc cttatggcat atcaagcact ttatcgagtc tggcgttcgc
    20161 agcgtttcga agacatcgtt ggacaaaaag ctgtgacaca gacactaaaa aatgctattg
    20221 tttcccacaa aacctcacat gcctacttgt ttacaggacc cagaggaacc ggaaagacga
    20281 gtgcagcaaa gattttcgca aaagcaatca actgtccgaa cagtaaagac ggtgagccat
    20341 gcaacgaatg cgaaatgtgt cgatcaatta ctgctggtac gcaagaagat gtgatcgaaa
    20401 tcgatgctgc cagcaataac ggagtcgaag aaatccgatt tatccgtgat cgggcaaatt
    20461 atgcgcctac aaaggcagcg tacaaagtgt acattattga tgaggtacat atgctttcaa
    20521 caggagcttt caatgccttg ttgaaaacat tggaagagcc aaaagaaagt gtcatattca
    20581 tcttagcaac gaccgaacct cacaaaatac cagctacgat catttcacgg actcagcgat
    20641 ttgattttaa acggatcaat acggcagata ttgtcgaaca tcttgaattt atcttgaaag
    20701 aatcgactat cagctatgaa ccagctgcat tgaatgtgat tgcccgttct gcagaaggcg
    20761 ggatgcggga tgcattgagt attcttgatc aggcaatctc gtttagtgaa ggaacaatta
    20821 ctttagatga tgccatgcaa gtgacaggta gcttaactga cgaaatgatg gacagttact
    20881 tgagtgcttg cgtgaaaaaa gaagtaccag aagcattgga aacattgaac caaattctcg
    20941 cagccggcaa agaatcacgt cgctttctag aggatatgtt acaatactgc cgtgacttgc
    21001 tgatgtatca gcaagcacct aacctagttg aggaacaatc gagtacgatc agaagtacat
    21061 ttacagaatt ggcacaaact gtttcagcgg atcagctgtt ttcaatgata aagattttga
    21121 gcgatactca aaatgaaatt cgttttacca atagtgccgc tatttatttg gaagtcgcta
    21181 cagtcaaact tgcacagcta ccgtctgctt ctgttccttc agcagatgta gcatttgcag
    21241 atgatcagat agtaaaacag ctacaacaag agattaagga actaagaaac gaaatcaagg
    21301 aactacgcag taatacagga attgagaata caaaagtaca gccggtacag caaacaaatc
    21361 ataaaaaaca gacaagtacc tatcgtgtac cgacggaacg agtatataaa gttctgcggg
    21421 aagcgacaag acagcatctg aaccaagtaa aagaagtatg ggaagacttg ctgatgagtc
    21481 tatctgtcac tcagcgagca atgcttaaag caagcgaacc agttgcagct ggacctacag
    21541 gactagtgat tgcgtttgat tatgagattg tttgtcaaag agcagcaaat gacgaagaat
    21601 tgcagctttc ggtacacaac aacttaagcc gaatgatcaa agattatgcg cctgatcctg
    21661 tttatattac aagagaaagc tggccagaac ttcgaagaaa ttatttgacg caggcacaag
    21721 aagagggaac agaaaactct tttgcttctg aagactcaga aggagaaatc gagttgcttc
    21781 ctcaagaaca agaagtacca gaagaaacac ttgtagtaaa agcagaggaa ctgtttggct
    21841 ccgaagctgt tacagtggta gatgattaat aaaaaggagt agataattat gatgcgtgga
    21901 atgggcaata tgcaaggcat gatgaaacaa gtacaaaaaa tgcaaaaaga aatggcagaa
    21961 gcacaagagc tgctaaataa aacagagttt acaggtaaag ccaccaatga attggtcaaa
    22021 gcggttttta caggcgatcg tcgcatgaaa gatatccaaa tcaatgaaga agtcgttgat
    22081 cctgatgata tcgagatgct tcaggatctt gtcgtaatgg cagtcaatga tgcgatcgca
    22141 caaattgatg tggaaactga gaaaaaatta gggaaatacg caaaaggttt gccaggattt
    22201 tagttttaaa ctgaaggagt aatgaatatg caatatccag aaccaattgc gaaactgatc
    22261 gacagctaca tgaaacttcc aggaatcggt cagaaaacag cgacaagact cgccttttat
    22321 acgatcgata tgaaagatga agtagtaaat gaatttgcta aatctttgtt aagtgtaaaa
    22381 cgcgatttgc atttttgtag tatctgcgga aacatcacag aagaagatcc ctgcgaaata
    22441 tgtagaaatc cttcacgtga tcgaagcgtt atcctagtgg tcgaagagcc gaaagatgta
    22501 atggcaatgg aaaaaatgcg agaatatcac ggactttatc atgttctcca tggtgtgtta
    22561 tcaccgatgg aagggacagg tccagaagac atcaatattt cttctctgtt gcagcggctg
    22621 catgatgcag atgtaaaaga agtgattatc gcaacaaatg caacaacaga gggagaagca
    22681 acagctatgt atctctcacg tctgatcaaa cccgcaggta tcaaagtgac tcgtctagca
    22741 catggtctgt ctgtaggctc tgatatcgag tatgcagatg aagttacttt attgaaagct
    22801 gtcgaaggaa gacgtgagtt ataaatttct aattaagtgt tttttcagat acaatataaa
    22861 agcagcacaa gagatggggg caacaatgtg aacggactat ttattacaat cgaggggcct
    22921 gatggtgcag gaaaaaccag catcttgaat gaactttacc ctcttttgaa agaagtagca
    22981 aaaacagaaa tcattcaaac aagagaacca ggaggcattc cgattgctga agagatccga
    23041 gcagtgatcc ttgatccaaa aaatgatcgg atggatgaac gtacggaagc actgctttat
    23101 gcagcagcaa gaagacaaca tctagtcgaa aaggttctgc ctgctctggc aaaagggaaa
    23161 atcgttttat gcgatagatt tgtcgacagt tctcttgctt atcaaggtgc aggccgacgc
    23221 atcggcgtta ccgagattgc tcggttgaat gagtttgcta cagaaggtac tacgccggat
    23281 tttacccttt atcttgacgt agattcagac accggattaa gaagaatcaa gaaaaacaga
    23341 caaaatcaaa tcgaccgttt agattcggaa ggtttggaat tccaccagcg tgtacgtcat
    23401 gcttacttaa agctggcaga agagaatccg gaaagaatcc acaaagttga tgcaagaaaa
    23461 agctttgaag aagtgctgca aacaagttat catacaatta ttgaacagta tccgcaattt
    23521 tttgaaaact aggaaggtga acgtttatga aaattatttt agcgattatc caagacaaag
    23581 acagcaaccg tttatcaaat gaattgattg atgcaaatat ccgtgccaca aaactatcat
    23641 cgacaggcgg cttccttaag gctggaaaca gtacgtttat cgtgggtatt gaagatgacc
    23701 gtgtagaaga agcattggaa atcatcaaaa aaacgtgtga atcaagaaag caatttgtat
    23761 ctacacctgt tacactggat atttcgatgg atgggggcgt cccttatcca gtagaagtag
    23821 aagtaggcgg tgccacagtc ttcgtcttac ctgttgaagg attccatcaa ttttaggagg
    23881 agctgagcta tgaatcaaga aataaacttg gctcaaatgc aaccgatcgt gtatcagcag
    23941 cttcaacgga gttttgagca tgggcgtatc gctcatgctt atctttttga aggggagaaa
    24001 ggaacaggaa aacatgaagt aggtatatgg cttgcacagc acctgttctg tacccaaatg
    24061 aaagacaatc tgccttgtgg aaaatgcaac aattgtcagc ggatcgaaaa gaaagaacat
    24121 ccagatgttt tggttattga accggaagga caaaccatca aagtcgatca gatcagacgt
    24181 ttgcagacgg aattcagtcg cagcggttac gaatcaagaa aaaaagtttt tttgatcaaa
    24241 gaagctgaaa aaatgaatag cagtgcggca aacagtttgt tgaaattctt ggaagagccc
    24301 cctggagatt ttttagcggt gttagaaaca gatgcagtag gaagaattct ccctactatt
    24361 caatctcgtt gtcaagttct gcattttcaa gaactttcga aagaagcact gatccatcga
    24421 ttgcaagaag agcagattcc attggaaaaa gcaaaacttt tggctttctt aacaaacagt
    24481 ttaggaaaag cagttgaaat ctctcaagat gaatggttta atgatgctaa ggacttgatt
    24541 tatcaatggt tcgtttactt gcaaaagcaa gatactcaag cctttatcta tgtccaaaaa
    24601 aaattggtaa aatcatttaa agaaaaaaca caacagttta caggattatc tgtcttgatg
    24661 ttttattatc aggaagcaca gcgtcaagca gtagcaaacg gcgaatatgg caaagtgaaa
    24721 cagataaacc agataattga acggatattg atcgcagagc agaaactacg cagcaatgtc
    24781 agttttcagg ctgttgcgga acagttcgtt ttgcatacga ttttttagct tgccgcaaag
    24841 gatgatgatc aaggaggatg gaaatggtag aagtagtagg tgtccgatat agagatgcag
    24901 gtcatatcta ttattttgca ccaggagact ctgaatatgt ttatagtgac aaggtattag
    24961 tcgaatctca gcaatcctta catattgcta ctgttgtcct tcctaaaaaa gagattgatc
    25021 ccaatgacct tcctgaagct atccgtccga tcttgcataa agcgtcacaa gctgaattag
    25081 aaaaagacaa aaaaaacaaa aaagatgctt atgatgcatt gaaaatcgca aaagaaaaag
    25141 tgcagttgcg tgagttggaa atgaaaatgg tcaaagccga atacacattt gatcgaaata
    25201 aattgatttt ttctttcaca gcggacgggc gaattgactt tagagaattg gtaaaagatc
    25261 tggccgctgt atttcgtact cgtattgagc ttcgacaaat tggtgtccgc gatgaagcaa
    25321 agataatagg cggaattggt ccatgtgggc gtccattatg ctgttcttct tttttaggcg
    25381 atttcgtgcc tgtatcaatc aaaatggcaa aagatcaaag tttatctttg aatccaacaa
    25441 aaatttccgg tttatgcgga cgcttgatgt gctgtctgca atatgagagc gaagaatacg
    25501 agacagcgaa aaaagaactc cctgactttg gaaaagtaat tgctacacct gatggtaaag
    25561 ggaaagtcgt agggttgaat ctgcttagcc gtatcgttag tattcggctg actggacggg
    25621 aaaatcctgt cgaatatgaa tgggatgaat tgaaagaatt tatccaagta ggtgagatga
    25681 atggataaga gatcattata cgacggattg aatcaattag aatcagagtt gagaaataca
    25741 ttaacagaac ttgttgaaat gaagcatgct ttgcatgaga tcgtagaaaa aaatacaact
    25801 ttggagatgg aaaatcaacg tctgcgggaa cacctgcggg aattgaacca agttgcacaa
    25861 gctccagctg aaaatgtgaa gcaggaactt tctaagtctc gtatgaatct tgaaaaaatt
    25921 tatgaagaag gattccatgt ctgctacgat ttatatggat caagaaggga caatgacgag
    25981 ccttgtgcgt tttgtctaga agtgatctat cgcgaaagcg gtcgatgacc aataacaaga
    26041 ggagactgga gcggagaaat actgctccag tctttttatt aaggagattg tgacagatgt
    26101 ataatcaaaa aagtttcaag ggaaatccgg tatatgggga tttatatctt gtaccgacgc
    26161 caattggaaa tttagaagat atgagctaca gaagtgttcg tatgctgcaa gaatccgatc
    26221 ttatcgcaag tgaggatacg cgtaatacac aaaagttatt gaatcatttt gaaatccata
    26281 caccccaaaa aagtttacat gaacataatt ataaagaacg tgtccctcaa ttgattgctt
    26341 tgttaaaaga aggaaaaacg attgctcaag tcagtgacgc aggaatgcct tccatcagcg
    26401 atcctggaca tgagctagtt ttagcctgca taaaagaagg gatttctgtg atctctatcc
    26461 caggacctac agctgggatg acggctttga ttgcttcagg gctagtgcct caaccatttt
    26521 tattttatgg cttccttcca cgtaagaaaa aagaacagaa agaaacattg aaaaagctaa
    26581 aagaacagac agttacgctg attttttatg agtcacctta tcggatcact gctacattga
    26641 cgaatttctt agaaattttt ggaaatcgcc aagtcgtttt gtgtcgggaa ttgacaaagg
    26701 tccatgaaga ataccttaga ggaagtacgg aagagctact cgcttatatc gaagaacatc
    26761 cagtaaaggg tgaatgttgt ctgcttgtag aagggaattt gttcgaaatg ccagtgacgg
    26821 aagttgatga agagttggga acgttaaagg aacaagtaga agcaaagatc gcttcaggcg
    26881 aaaaaccaaa tgctgctatc aaagcagtag cgctgaaaaa tgggctgaaa aaacaagaag
    26941 tctaccgtca gtaccatgaa ttagactgag atagtataag ttgtctataa tgaaagacta
    27001 atgaggaaat cagctactaa cttttcaaat ctcttgaacg cgaacgaatg ttcttgtata
    27061 atgaataaga ggtgaggatg atggagctgc aatttccttt acataatgat acatcaagaa
    27121 aaatcattca tattgatatg gatgcttttt tcgcttcggt tgaagaacga gatcatcctg
    27181 agtttcgcgg acatccatta gtaattgcca gacaccccag tgacactggt gggcgtggag
    27241 tagtgactac agcaaattat gaagcaagaa aattcggaat tcattcagca atgagtgcac
    27301 aaaaagcgta tgagctttgt ccgcaagcca tctttaagcc tggcgaccat cataaataca
    27361 gcgatatttc caaacaagta cgggaagtat tctatcgtta tacagatatt gtggaaccag
    27421 ttagtatcga tgaagcgtat cttgatgtga ccgaaaataa aatcaattgc aagtcagcca
    27481 tcaaaatcgc ccgaatgatc caagcagata tttgggagag tgtccagcta acatgttctg
    27541 cgggagtaag ttacaataag tttttggcca aattagcatc agactatcaa aaacctagag
    27601 gaatcacggt agttgcccct caagacgctg tgccattttt aaaagctttg ccaattgaaa
    27661 aatttcatgg ggtagggaag aaaactgtac ctagaatgca tgagctaggg atttatacag
    27721 gaaaagacct atatgaatgc acagaaatga tgttgattcg aaattttgga aaaatgggct
    27781 attctcttta tcgtaaagtc agaggaatcc atgattctcc agtaaacgtt acaagagagc
    27841 gaaaatctgt gggaaaagag catacttatg ggcagccgtt gcaaacggaa gaagcagtgc
    27901 tgactcagtt gcgccaacta gctgaaaaag tagaagaagc actgagaaga gtccaaaaac
    27961 atgggaaaac agtagttttg aaggtcaggt acacggacta ttctactgtg accaaaagag
    28021 tgacattgcc agaatatatc tataaaaaag aagcactctt ttatcaagca agccttatat
    28081 gggaggaaat cttgggagta gaaaaaggaa tccgattgtt agggattact ttgacgaatc
    28141 tggacccgat gacttatgaa aacatcgtcc ttccattatg ggaaaatcaa gaaatataaa
    28201 aacagctttg agagttgaaa ccggaaatcc gttttctctc ccaaagctgt ttttatatca
    28261 agtcttgctt tttgatttgt tcataggttt ctgttgcatc cgtacatttt tcccaaatca
    28321 caacttgatt ggattctaaa gatttttgga cgtcaatgat ccgctggttg ctacttccgc
    28381 gaaattgtag ttttaggtca cgtttgctta attcaaagcg tccgtcaaca aggatatcga
    28441 tttgcgaaag gagttctaat ttatcttctg aatcttgtag caattcatca aaggtatagc
    28501 ctgtccatga ccagatatct tttgtcgtac cgaactcttt tcggatacgt cgtacgactt
    28561 gcagacaaac atctgtattc aaaaaaggtt cgccaccaag taaagttaat ccttgcacgt
    28621 aatcgttgcg caagtcagcg atgatttgtt cttctaattc aggtgtgaat ggtttgccat
    28681 atcggaaatt ttgtgcagct ttgttgaagc agccttcgca ggcaaataag cagccactaa
    28741 cgtaaagact gttgcggaca ccttcaccat cgacaaaatt aaacggtttg tagtcagcaa
    28801 tatagttttg gctgtagtct tttgctaacc attcttttgg ttttggattt ctcataaaaa
    28861 aacttctttc atttaaggtt caaagatata gctattgaag ataaaatcta ctcgaccaca
    28921 taaataagaa caaactgacc taaatccatt gttcaagaaa gcttgttctt attttgatag
    28981 agggcgttca aagatacaaa gccatcgaaa gagggtggtg aaaaaagact tgtcatagcc
    29041 tcttattctg aataaacggt gttcaaaagc ttgcatctgc agtaataagc ccaactaaac
    29101 gaaaaatatg aggaactatt tttgtttagc tattcttatt acttgatgca ggacagcttt
    29161 ttcacaacct catttcatgt gtttcacacg tgaggaaatt tctttatggc ggccatgtac
    29221 catcggacga gcttgcggat ttcctaaata gccacaagta cgtttgacta catcacatgt
    29281 ttttggatca tgatttccac attctggaca ttcgaaccct cgttctgtcg gtttgaaatc
    29341 accttcgaaa ccacattgat agcaatgatc gattggcgta ttcgtaccaa gatacccgat
    29401 tttgtcatat gcaaaatccc atacagcttc taaagctttc ggattttgtt ggagcatagg
    29461 gtattcacag tagtggatga atccacctga acaatatttt ggataatcct tctcaaattc
    29521 caatttttca aatggcgttg ggtttttacg cacatcatag tggaaactgt ttgtataata
    29581 ttctttatct gtgatatttt cgatgatgcc gaatttttct gtatccaaac ggcagaaacg
    29641 gtcagttaga ctttcacttg gagttgaata gacactgaaa tgataaccat attcatcccc
    29701 ccatgcatct gcattagctt ttaattcttt gacgatatca agtgtgaaag cttttgcttc
    29761 tgggtttgtt tcccattcgc caccgaagaa agctgaagca acttcataca atccaatgta
    29821 gcctaacgat acagtagctc gacggttttt gaataattca ttgacagaat cggtacgtga
    29881 aagacgtttc ccgaaagcac catacatata taaaattggc gcatttgctg gaatggcttc
    29941 tttacaacgt tctacacgat agagaagcgc atctttcatg atttctaagc ggtcagacag
    30001 taactgccag aatttattct gatctccttt tgattcgatc gcgattcttg gcaaattcaa
    30061 tgtaacaaca cctaaattca ttcgtccgac atttacttct tgaccatttt cgtctttcca
    30121 cccttgcaag aatgaacgac agcccatagg tactttgaaa cttccagtta attcaacgat
    30181 tttatcgtaa ttcagaatat caggatacat tcttttcgtt gcacattcca atgctagttg
    30241 tttgatgtcg taattaggat cttcagggtt taagttcaca ccttttttca aagtgaagat
    30301 cagtttaggg aagatagctg tccgcttttc actccctaat ccattgattc gaatctgtaa
    30361 aattgctttt tgaatttctc tttcaaacca gttttctcct agtccaaatc ctaatgaagt
    30421 gaaaggagtt tgtccatttg aagtaaataa ggtattgatt tcatattcca aactttgcat
    30481 agcatcgaag atatcttttt tggtttttgc ttttgcatat tctttttggc gttctggcga
    30541 atcgatccat tcttccgcgt cttttagatg ttttttatag ttcaattctg caaaaggagc
    30601 aagcaattca tctgttcggt cggcagaaca gccaccatat tgacttgacg ctacattggc
    30661 aataatctgt gagatttgtg ctgtggcggt ctggatagat tttggcgatt cgacttcggc
    30721 attgccgatt ttgaacccat tgttcagcat gcctttgaaa tcaatcaagc agcaattcgt
    30781 catcggtgta taaggatgat aatccaaatc atggtaatgg atatcgcctt tttgatgcgc
    30841 atttgctata tgtggtggca acattttcag tccgattgat tttccaacga tcccggctgt
    30901 cagatctcgc tgtgtattga aaacattact gtctttattt gcgttttcgt tcacgacagt
    30961 ttggtccttg ttgattagct tttcaatcga aaagttgata tctgttgctt tactgcgagc
    31021 aaaatctcgt ttggtacgat aattgatgta ctcttctgct aattcatatt cgtttttttc
    31081 tagtaatata tgttccacga tgttttgaat ctcatagatt ttgacatttt cagcaaaccg
    31141 gcttttgatt tcttggacaa ccaagtctgc aatcatttga attttttcat aagtaagtgg
    31201 tgataatgag ccgtgaattt tcttttctgc tttgatcagt gcttcattga tcttttgttc
    31261 atcgaaatca acatggcggc catcgcgttt gatgactttc atctgggatg tctctggctg
    31321 ctgagtaacg acagtttttt cttcataatt tactttcatt atcttcaact cctgctaaat
    31381 tgttcttgtc tatcataaaa caaaatcggg gaaggagcaa ctaaatatcg gctatatata
    31441 gtattcaatg tgctgtataa ttggatttct atactatatg tagtgtatat tttattgtga
    31501 aaaaaggtga aaacttgtag ctggtggatt tgttttttgc atatttaatt ttgctgaata
    31561 aaataattga ataaaatttt ttattcagtc caagtaaaag tgacaaaaac ataagagcaa
    31621 attattcgta gatatgctac tatgcaaata aatagaaatg aaaaatgaaa gaggaggaga
    31681 agaattggaa aagatgatcg aagtgaaaca tctaagtaaa agctacggca gcaaactttc
    31741 tcccgtcaaa gccttagata atatctcatt cacagtagaa gaaggcgagt ttgttgggat
    31801 tatgggccca agtggtgcag gaaagacaac gctgatgaat atcttgtcca cgatcaattt
    31861 gcctacgatg ggcagtgtct cgatccaagg aaaagaaatc acaaaaatga aaaacagtga
    31921 gctcagtgac tttcgtcgaa aaaaactagg attcattttt caagagttca atttgatcga
    31981 taccctaaat gcaaaagaca atatcctatt gcccctagca gttgaacgga tgactaaaga
    32041 ggaaatggaa aagagagtaa gacatgtagc tcaattgttg aatatagaag aactgctcaa
    32101 acggtatccc gatgaacttt ctgtcggaca gagacaacga attgcagctg ctagagcact
    32161 tgttgttcag ccacaagtga tttttgcaga tgaaccaact ggctctttgg actcgaagtc
    32221 ggctacagaa ttgttgaact acttgaagac catgaatcaa aaagaaaaag caacgatact
    32281 gttagtcacc catgatccat atacagcaag ctactgcgat agaattttat ttattaaaga
    32341 tggtgtgatt ttttctgaag ttgtcagaag agggacaaga agagagttct ttgagaaagt
    32401 aatagacatg caggcgacga ttggcggagg aggaaaaatg aatgctgtat aaactagccg
    32461 ttaaaagttt ttttcggcag tcacgaggct atcttgttta ttttttcagt ttgactttat
    32521 ccgtaatgat ctattattcc ttcagcgcaa tgacctacga tcaatcttta gtcagaagag
    32581 caagtcaaga tacttcgata gatggtggat tgagttttgg tggatttatc attactgttg
    32641 ttttgctttt tttcgtattc agtgccaacc gatttttctt gaatagaagg caaaaggaaa
    32701 taggcatcta tcagcttttt ggtatgaata aactgcagat atcaggtata tatgtgttag
    32761 aaatcatgat aattggattg ttcgcctgta tttctgggat attactcggt attatttttt
    32821 ccaaactctt ttcaatgatt ttggttcgaa tgatggatat ggatcttact agtccatttt
    32881 ttatctccat tccatcagta gtagatactt tatttgcttt tttcatcatc cttttagcag
    32941 tatctgtata ttcaatatgg aaaatatggc gctatccaat gattcgaagt tttggagaaa
    33001 aagaacaagc agatagttca acaatgcgct tcaggacaag gcaccgatta ctcgcagtca
    33061 tcgggttact acttttaacg agcggatatt ttggagctag tcattttagg gaaatcactt
    33121 catggatgat cagttatcat tatcttgata cattagtttt cttttttcct tttttaattt
    33181 ttttcgtttg tgtggtcggt acttatttgt ttttctgtta tacatttcgg ttatttttga
    33241 tcatattgag taaatggaag atttattact atggtatcaa ttttttgata atgggtaaca
    33301 cgcaagttca tttgctcaaa agttggcgta caaattctct gattacagtc attctcggaa
    33361 tttctttaat gacaattggc ggcacggcta gtatctctac tattttatcc taccaggaga
    33421 aagtttcctc cccgatggac tatcagtttg atgttgagac agagaaaaaa atcaagccga
    33481 ttctagcaga ggaagggcag aagataacta aagaaatcac cttgcattat aaagtcattg
    33541 ggagtatcta tagtcaaaat ctcgaagaac ctatgtttca aactgctaat ctgatcacgg
    33601 aaacacaata tcaagccttc agaaaagtta atccagattt gccgaacatt tctttgaaat
    33661 cacctggtca tactgttttg cttgatcaaa tgcaaactct ttttcggaat atttcattat
    33721 atggatctag tattggactg ccagataatc aagaattgaa gattcaacaa atgcttccaa
    33781 gtgtattagg tgacgaaaca atggtatatc taagtcctgt actgattgta gatgataccg
    33841 tttttgaaaa agcaaaaggt gtggattatc aagtagtcaa tgtagatgta tcaggtggaa
    33901 ataatgaaaa aatagatgaa cgactgagca atgacctgtc gataaagtgg ctcaatgctg
    33961 tttattattc ttatgatatc gtaaatggaa gtctacaagg agaaattagc acaaagaaac
    34021 ttccggatga ccaaatgaag gaagcacaat ttagccaaga aagctctcgt ttgaatttct
    34081 cttccagcta ttcgaaattg cgtgcagtta atcggcgaat cggtatcaat atttttgtca
    34141 cactatttgt cgggatgatc gtgattattg ctactggtag tattttgaca gtccggcaat
    34201 tagcagaagc agaggaagaa aaagaaaatt atcacctatt gactaagctg gggattccac
    34261 aaagaaggat cagacggatg atcttcgagc aaaacgcact taccttcttt ccacccatga
    34321 tattagggat cactcacgca gtatttgcaa tcaatgtctt cactcagtat ataaaaactg
    34381 ccgattactg gttggcttat cttgtgagtg gcttattgat ccttatctat cttttgcttt
    34441 atgtcattac gagtcagtta tattgtcgga ttatcgagga atgatatacg gaataagaca
    34501 agataataaa tagaactaaa ttttgaatac catttatttg gaataagagg ttgtgacacg
    34561 atttttgtca caacctcttt attttttata ttttttaaaa gtacgagaaa ttataaagaa
    34621 aaaagcagtg atttgatgtg ctatttttat aaaagctatg tgacaaaact gttagtaaaa
    34681 aaacggtttc tgtaagctag acacatgttt ctttttgtca aaattagtta cactttgtgt
    34741 gaggttatat gaggagggaa tccaatgaac aaatggcgtt ctaatccaaa attgaattat
    34801 tggggaaaat tcatcattcg aacaattttt tatagtgcag tactgctgtt cctgatttat
    34861 ctgtatcact ataaaaatat tcaaggagga acttttatct ataacgaatt ttaggaggaa
    34921 gagtatggaa atcaaaacga ttattgaagc aatcgatgat tggggaataa atgaacctga
    34981 tcgagttgct tatcaggcgg atgagacgca tacttttggt gaattgaaac aagcatcaga
    35041 cgcacttgct tattatttag aaaaaaaggt agaaggcgat ggaccaattg tcgtttttgg
    35101 caatttggag tttgaaatga ttgtctcatt tctaggggtt gtcaaatctg gccatgccta
    35161 tttgccgatt gaagagcata cacccaagga gcgtatccta tcgatctttc gggtggctaa
    35221 accatctatg gtcatcagta tcggggactg gatagaagat attccttcgg ttcctgtcat
    35281 aacaaaaaaa gaatttcaag aaatcaagaa gataccagta ggattttatc ccagaaatag
    35341 cgtaaaaggt acagaaaatt tttatattat ttttacttct ggtactactg gagaaccaaa
    35401 aggcgtacaa atcagtcatg ataatctagt cagctttgtt caatggacga tggaagactt
    35461 tgggatcaag cctggtatgc atttcttagc ccaagcgcca ttttcttttg atttatcggt
    35521 attttctatt tatcctgcat tagtttctgg cggaatgctg aagccgttaa ataaagcagt
    35581 tgttcaagac tttcgtcaat tattcgcgac attgccagcc ttgaagttga atgtgtgggt
    35641 ttctactcca tcatttatgg atatttgctt gatggaacct acattcaatg gagaaaatgt
    35701 gccggaattg gacatgtttt tattttgcgg agaagaattg acgaaaaaaa ctgcagaaag
    35761 tctacttgat cgattcccaa atgcacggat atataatact tacggtccaa cagaagcaac
    35821 tgtagctatt tcaagtattc agattgacca gcatgtacta gatagttatg accgactacc
    35881 gattggctac gtaaaaaaag acacgaaagt ttctattgtc caagaaggta aacctgtttc
    35941 aaaaggagaa acgggtgaaa tcattattgc aggaccaagc gtatcaaaag gttacctgaa
    36001 caatcccgaa aagacagctg ctgcgttctt ttgtcaaaat gacttagcaa gttaccatac
    36061 aggggatgca ggtagactag atgaatatgg gcttttattt tatgaaggac gtatggatca
    36121 gcaggtcaaa ttacatggat accggattga actcggggat atcgaacatt atctgctcca
    36181 agacaaccga atcaaacaag ctgtcgtcgt accaaaatac caaggaacaa aagtacagca
    36241 gctggttgct tttgtcgtat tagaaaacaa aacgaaacag ccggattttc agttgactaa
    36301 atctatcaaa gaacaattac tagaagttgt aatggattat atgattcctc agaagttcca
    36361 ttatgtcgat ctgctgcctc agacagttaa tggaaaaatc gatcgaaaaa aattaacagc
    36421 tgaggtgaat cctgaatgat gttacctcat atgatccctt atgcagagcc gttttatttt
    36481 tttcttttag ccattgcgct tgtaccgatc gttctatctt tattgatatg ggaaaaaaga
    36541 ttaccagttt atcaatcagc agtgacactt ttctttttat ttgtcagctt tggaggtaat
    36601 tattggcaac agggagcggc gctgattggg tatgttttgt ggcagacgat acttgtatgg
    36661 ggctattttg tttatcggca aaggaaaaat cagacaggat ggttttttgc cgccgttatt
    36721 ttagcgataa ttccactgtt tttaacgaaa gtgactcctt tttttgaaca tggaaaagca
    36781 tcgttacttg gttttttagg aatctcttat ttaaccttta aatctgtaca aatgatcatg
    36841 gaaataagag atggcatgat caaaacatat aagccatttc gttatatcca gtttctgctg
    36901 ttctttccaa caatctcttc tggaccaatc gatcgctata ggagatttga aaaagatcag
    36961 ctccatccgc ctgttcgtga taaatatgtt gatcttttgg gaaaaggcgt ccaaaatatt
    37021 tttgtcggtt ttttatataa attcattatc ggttattatt ttggtcaagt actgcttcct
    37081 gtagtgggac gcattgcctt acagcatggt ggtatttcat gggcattagt aggttatatg
    37141 tacgtgtaca gtatgtattt gttttttgat tttgctggct atagcttatt tgcagtcggt
    37201 acaagctaca tgatgggata tcagacacca atcaatttca ataaaccttt tttatcatgg
    37261 aatatcaaag aattctggaa tcgttggcat atgacgctgt ccttttggtt ccgtgattat
    37321 gtatatatgc gattgatgtt cttcatgatg aagaaaaaat tttttaaaag caagatcgta
    37381 atgtcaaata tcggttattt tgctttgttt cttctaatgg gtatatggca tggattgacg
    37441 tggtactaca tcgtatatgg actgtatcat gcttgtctga tctgtctgac agatgcatgg
    37501 atccgattta agaagaagca taaagagcag ttgccttcta acaaatttac gcatggctta
    37561 gccgtatttt tgacatttca agcagtatgt tttagcttcc tgattttttc aggattttta
    37621 gataaacttt tttttagcta acgaatagtg acatattaat ttatataaca aaggagaaaa
    37681 ggaaaatgga agaacaaatt ttatcaatct tagaagaaat aacaggaaca gatgaagtaa
    37741 gaaaaaatcg tgatattgat ctatttgatg aagggttgct tgattcttta gcatctgttc
    37801 aattattagt cgagctagac ggagagctgg atatccaagt ccctgtatct gaattcgagc
    37861 gagaggattg gagcacaccg aataaaatca ttcaacaagc aactgcattg aagggttgag
    37921 tatgaaaaag aaactttttg ctattttcgg cccggttgtt ttagctgttg gcttactgtt
    37981 tgtgtttttt acctcctcct atcaagtaga tatctctaat ccagaaacga ttagacgtgc
    38041 ctcttcttcc atgtcagtga acgtgttgaa aggagatgcg ataaaaaatt atgcattatc
    38101 tgaaaaacaa tatattcctt tttttggctc aagtgaatta agcagaatca gtccatttca
    38161 tccgtctgtt ctggcagaaa aataccagcg aaactatcgt ccatttttgc tgggagcacc
    38221 cgggacacaa tcgttaagcc aatatatgat gatgcgttct gcaggagatg ctatgaaaaa
    38281 caagaaagtc gtctttatta tttctcctca gtggttcgtt aaaaatggtg taaaaactga
    38341 ttactttaat acgtattatt ctgaacttca aacatacgac tggttgtttt caatgaagaa
    38401 agtaacgcct gctgatcgct atttagctag aagattatta actttctcaa aagtaaaaga
    38461 gaatgatacg ttgacggcga ttctgcaaac gatcaaaaaa gggaagctac ctttacctga
    38521 atctttgaat cagctgcgca gccaatggaa catgctgaag agagaggatg aagtattcag
    38581 caatattggg ttgaaagatc gacagcaaaa aatcgatcat gagtcaaaac gattaccaaa
    38641 acaataccaa gaaacagaat tatccatttt agcaaatcaa attggagaac gagaaacgac
    38701 gaataatcca ttcgggttga aaaacgattt ttatacgcat cgtatccgag cccacgagcc
    38761 agagctcaaa cagtcacaaa aaaattggga ttatcgtttt tcgccagaat tttctgattt
    38821 tcagctggtc ttggatcaat tagcaaaaaa ccataacgaa gtattgttca tcatcccacc
    38881 ggttaacgag aaatggagcg attataccgg actatctcaa gaaatgttac aaggatttgc
    38941 caaaaagatc aaatttcaat taaatagcca aggattcaat cgaatagctg attttgtcaa
    39001 tcaagcgggt accaactatt ttatggaaga cacgatccat ctaggctgga aaggctggtt
    39061 ggctgcagat caacagatca gaccgttttt agaagaaaat catattactg ctagtaagta
    39121 tcatcttgac gatgcttttt ttagcaaatc ttggcaacat caaataccag ataaactaca
    39181 attaaaataa agaaaacagg cgagtgttgc tcgcttgttt tctttatttt tgaatattct
    39241 gaataaaaga taaaaatacc aagtttgcct gaacaaaaat cataagcaat ggtataatca
    39301 caatatgaat atagaaatgg gggaaaacat ttggatacaa aagaagaaca gctacttatt
    39361 gatttaactt ctgcaaaagg agtacctgga aatgaagaag aggtaagaga agtattcaga
    39421 gaatatgcca aaccattcgc tgatgatatt ttttatgacg gtttaggcag tgtgattgcc
    39481 aaacatggtg ctggcggagg ccccaaggtc tttatttctg gacatatgga cgaagttggt
    39541 tttatggtaa caaaaataac cgaaaaagga ttcttggaat tccaaactct tggaggttgg
    39601 tgggggcaag tcatgcttgc tcagcaagtt gaaatcaaaa cacgtgaagg gaaaatcgtc
    39661 cacggtgtga ttggttccaa accaccacat gttttaacac ctcaagtaag aaataaacct
    39721 tatgaaataa aggatatgtt cattgatatt ggcgcatcaa gccaagaaga agccaaagag
    39781 tggggcatac gtcctggaga tatggtcact ccatatattg aatacaaacg aatgaatggc
    39841 agtaaatatt tactggcaaa agcatgggat aatcgtatcg ggacagctgt ttctctgcga
    39901 gtattagaga atctatctaa agaagcacac ccaaatgttt tattcgcagg aagcgatgtg
    39961 caagaagaag taggcttgcg aggtgctcga acaagtacac accttgtaaa tcccgatatt
    40021 gcttttgctt tagatactgg tacagcagga gacactccag gaatgacacc aaaagaagca
    40081 gattcgattt taggaaaagg cccacagatt ttgatttttg atgcatctat gatcccgcat
    40141 aaaaaattat tgaattttgt tattgatgta gcagaggaaa tggatattcc attccaatat
    40201 acagtgattt ctggcggagg aactgatgca ggacaaatgc atttgacaag agatggtgtt
    40261 ccgtctgtag ccattaccgt tcctgttcgt tatctgcatt cccatacatc agtgattcat
    40321 gaagatgatt atttgaatac agtgaaacta gtcacagaat tagtgaaacg gcttgatagt
    40381 gaaacagttg aaaaaattcg gagttatgaa taatgaataa tagaatacct atttctgaat
    40441 atcggaaaaa agcacgagtt tctttggaaa atcaatgggg aatcaatact tggcttgttt
    40501 tcttatctat aatatttacg agcgtcatcc agaacttttt tgacggtttc agtccttttc
    40561 cggaagaaag catgcagcag cacttattga gttttctagt cgataattta cttttattcg
    40621 tattcaacta tgcattgttt tacattgcgc tagtagttgt acggggtggc agaccaaaaa
    40681 gtaacctttt attttcagtt ttccaaagaa agtattttgg ttcgatactt ggcatcaatt
    40741 tgatcaattc agtcatcaac tggctactca acagtttaat ctttctgccc atgtttttaa
    40801 tcagcggagt gagtacttat atgcagctgc ttttcagttc aaatgcggta cctacgggtg
    40861 tcatgccaga agattttctt gatatcagct ttgttttatc gatgataggg atgatttttg
    40921 tttcagcact catcatgagt attgttggcg gtttattcca atttgctgca tggacaaagt
    40981 tcgactatcc tgatttgtcg gttattcaat gtttgaaata tggctggttt ttattgaaag
    41041 atagaattgg tacgtatatt ttgttgcagc tgtcttttat cggctggtat ttgctaggag
    41101 caatcgcttt gttcatcggt cttttgtggg tcattgttta tgtgaatgtg tcagttgcag
    41161 aattttatga acaagcacgg attgaaaaag gaggtccaga cgcctatttt acttagcatg
    41221 taagcagttt attcatcaaa aaaataactt ttgtggtagg ataaatcttt gagggggaat
    41281 gtacgatgaa attaactgtt ttaggatgct taggagcgta tccttataaa aatcaaggga
    41341 caacaggtta tttgcttcaa tctgacgggt tcaatttgtt gatcgatgca ggtagtgcta
    41401 cgctgatcaa attacaagaa caccttgatc cacttgatct agatgctgtg atccttagcc
    41461 attatcatca tgatcatatt gctgaccttg gtgtattaca gtattactgg caacttcatc
    41521 ctaagagaaa tccggagaca ttgctttcaa tttatggaca cacaaaagat tccattcact
    41581 ttgaagaatt gacgttggaa aatgtctcaa aaggacatcc ttattttgaa gctgaagaat
    41641 taaaaattgg tccttttctg attactttta tggaaacaat ccatccagta gtatgttacg
    41701 ccatgcgtat cgtagaagaa acaacgggga aagtattcgt atttacaggt gattcaggtt
    41761 atttggaaag tttcgctgat tttgcgaaag atgctgattt gtttctagca gatacctatc
    41821 tttttgaagg aaatgaacat catcatgccc atttcacttc aaaagaagct ggagaacttg
    41881 cgaaatcagc taacgtaaag aaacttgtac ttacacacct acctcagttt ggtgatttag
    41941 aacaattgaa aaatgaagcg caaaaggcag caggcaaagg gattgatata gaacttgctg
    42001 cagttgacaa agtgtttaac atttaggagg aagaacatga tttttgtacc aaatgaaaac
    42061 cacgacccaa gaatcaattt agcaattgaa caatatttgc tgcaagaaat gcctttagat
    42121 gaacctattt tgctctttta tatcaatgaa ccttcaatca tcatcggcag aaaccaaaat
    42181 acgcttgaag aaatcaatcg agattatgtg gaagaaaatg gcattcatgt tgtccgtcgc
    42241 ttaagtggag gcggagctgt ctaccatgat tttggaaacc tgaactttag ttttatcatg
    42301 cctgatgatg gggattcatt ccgtgacttt gcgaaagtaa cacagccaat catccaagca
    42361 cttcatgaat tgggtgttgc tggggcggaa ttgaaaggcc gaaatgatct agtcattgat
    42421 ggcatgaaat tttctggcaa cgcgatgtat gctaccaacg gtcggatgtt tgctcatgga
    42481 acaattatgt tcgactctga tatcaatgaa gtagtcaatg cattaaaagt aaaaaaagac
    42541 aaaatcgaat caaaaggaat caaatcgatc cgttctcgtg taacgaatat caaaccattt
    42601 cttccagaag aaaagcaaaa aatgacaaca gaagaatttc gtcaagaaat cttgttgaaa
    42661 attttcggcg tagagtcagt agaagaagta aaaacgtacg aattgactga tgaagattgg
    42721 aaaaaaatca atcgaatctc tgaggaatat tatcgaaatt gggattggaa ttacgggaag
    42781 tctccagatt tcaatttctc tcgccaaaaa cgtttttcta tcggttcgat tgaagtccat
    42841 ttgaatgtct cagaaggaat gatcaaagaa gcaaaaatct ttggcgattt cttcggacta
    42901 ggagatatct ctgacgtgga aaaaaaattg gttggacaga aatatgataa agcatctcta
    42961 tcaaaaatag tcagccaaat tgatgtgaag aaatattttg gtgcgataga accagaagaa
    43021 ttgcttacct tactttattg aaaataaaaa atagcggaat ccacatatat ggattccgct
    43081 attttttata caggattcgg gtaatttcga gagagttgaa cagtgatccg atcaatgaaa
    43141 gtatcttttt cctgcgttag tgttcctgtg taacgatccg ctacgtcttt catcatcatt
    43201 aagtcaaaac gttcctgatc atctaattct tctgtgatgc ctcgactaaa taggtttgta
    43261 tcgtaatgtg cactatgttc gcaacaaatg acgaaatgtt cctcttgttc gtgtatcgac
    43321 aaataaattt ttcgatacag tggattttcg atggcatgag tttctctaaa ggaatgctct
    43381 aaagcgtgga tcaaaagttg agccagatcg tcatcgttga taggaagttc ttcgggaaga
    43441 tctgcttgga aggttatctg aatattccgt ttggcagcta acttctggta acgcgctaag
    43501 ataagatttg tcacctggtg gttgcaaaaa gaacacagca tttcgaaatt ttttgcttct
    43561 tctaatatct tttccacata gtttttagct tttgtttggt ccgtatgcat taaatcttgc
    43621 agattctcca tctcttggac aaattccagg cgaagtgtat ttacttcttg gatatgctgt
    43681 cgaagctgct cataatgttg ctccaacaaa tcatttttga tttttaagaa atctacttgt
    43741 ctccgatctt tgtcggtatt taagatgtga tcgattagat tgtagctgat aataacgatt
    43801 agaatgataa tatataaaat cgtagaccaa ttgatcgttg tttgatagat acctaatgcc
    43861 gtttggatgt aaatcaagca atggataatg gctaccaaga cgatccaagg tgtacaagct
    43921 acataaaaac ggttattctt atatgcttcg ccaatgcatg caagtgaagt gactaaagtg
    43981 cttataacac tagcaatatt agcaatcggc attaattcag gaagttctgc aggagtaaaa
    44041 gttgcataaa gcagaacgcc gataaaaatc aaaagttgga acgtacaaaa aattccgtac
    44101 cattttttat agtaaaacat tcggctccaa tagtagcaga tgatgaaagc tgacgttaag
    44161 ataataaata aatgagataa aaaagaatga acgaatggtt caaaaagaat accacttaaa
    44221 atatcttctg atacagcttc aaatcctaat gccaaagcaa agcaacttaa gagaataagt
    44281 gagtattcaa gacgtttttg tttatacatc aagtagatcg tatagaaaaa ggtccctata
    44341 gcgataaaaa cagcgattat catcgtcaat acttgcggca ctgattgtga ataaataaaa
    44401 ctaatcaatg gtccagttgt tcctagataa actttcggtg gcagtccagc atagttctga
    44461 taaggagatg agactgtaag ggtcaatttt tttccgatat aatttgctgg taaatctatc
    44521 acagccaatg agagtccggg attgctttct tcctgataat ctttccgttg gtataaaatc
    44581 ttttcgccta gatatacagt aatccattga tggtttcctt tgattagtaa atttgcttcg
    44641 tccaacggtt tttcaagtgt cgtttccata atgaatgttt cgtctttatc cacggtagga
    44701 atcgtacgag tgtacttgct gtcaaactta aaatcaggat catcttttgt atagaaaacc
    44761 cacgaatctt ttatttcttt catttgattg ctgtccgcag gagaaaaaat aaaataaaag
    44821 aaataagcaa ttcctgttaa aaataacaat gataatataa tgattatgct ccactttata
    44881 cgtaaataaa aagattcttt tttattatat atgttattaa aaaaagacat aaaggtattc
    44941 ctttctaaaa cttgtaatgt tagggtaaac gttttttaaa ctaacgtcaa ttatttataa
    45001 taaaaaatga gataaagatg aggaaataga attagaaaca tataattatt aaagggaaac
    45061 atttttacag ctataatttg aaaaaaattt atcgttatta tatgattaag aaggattgaa
    45121 taaagaaaga agttgaaaac gatacctgat tacaaaaaaa taacttttat aagttctata
    45181 acgttgatta tatttttaat tcttattctt ctcgtcgtct tggttccccg aatttttggt
    45241 ttgactcctt atattattga ggacaaagaa atgagtccat attatgcaca aggaaatctg
    45301 atatatgtac gaccgaaaaa tacaaatgag attttagtcg gagatattat tacatattat
    45361 gaaaattcag gaaaaaaaat ctcgacgcgt cgcgtaatag ccgttgaaaa caaccacgaa
    45421 gatttttata caaaagctga tacaaagact tatattgagc ctggagtagt aaaaaagaga
    45481 aatattatcg gtagtcccat ctttcagatt ccatatattg gactagtcct ttcaaaaacg
    45541 gcatttgcat ggattcaggg gttattcttt acgattgctt tttgcctaac aggaatcaca
    45601 gcatggaata cctttgtaga gttgaaaaag aagcggagac gaacacagaa atttttgtaa
    45661 gaatgttaaa aacataaatg tattccagag atccaacgac tcttctgaac atgaaacacg
    45721 agaaaacact catgcagctt gtagatttag tcagttgttc gtataatgtg tgaagaggag
    45781 gagtagtatg cgcaatgaaa tgatgcatcg tcctgtagtc aaagaagaac tattggattt
    45841 tatgcgtacc cagcaaaaaa aattaccggg tgagctaggc aaactggaag aagaagctca
    45901 tgtagcagaa gtaccagtta ttccccatga aacagttgta tttttgaaat ttttacttgg
    45961 acagcttcag cctgaacgaa tcttggagat cggagcagct atcggttttt catcaagtgt
    46021 catggccacg acaatcggag aaaacgctca tgttacgaca attgatcgtt tcgatgtcat
    46081 gatcgagaaa gctaaaaaaa actatgaacg tctaggactg acagataaag tgactttgct
    46141 tgaaggtcaa gcagcagata tcttgccgga gttgtctggt ccgtatgact ttatttttat
    46201 ggatagtgca aaatcaaaat atattgaatt tttacctgaa tgcttacgtt tgttaagaaa
    46261 aggtggcgtt ttgatggtag atgacatctt ccaaggagga acgatcttgc tcccagatga
    46321 agagattccc cgtggcaaac gagctatcca tcgtaaatta aatgaatttc ttcgtgttgt
    46381 gatggatcat cccgatttga catcgacaat cttgccatta ggtgatggtg tgatcttaat
    46441 gacaaaggaa tcagaaacaa tcgagttgtg atacatgatt atggcagcct gtagataatc
    46501 gattgaatcg agggctcaat tcgaacttga tgtaaaagtt tctatatttg taagtcaatt
    46561 aaaggataca ggaaatctaa ataaacagga gtagcatgaa gtcaatgtag ctcctgtttt
    46621 caattgataa ccttagaaca gctgaaggag aatgtctcgt tttaaaagat tgatttagta
    46681 gttgggccaa aataattcat tatttgctaa ttaaataact atttcgtatt gacagaagca
    46741 atttaattat ctataattat tgatgttccg ctgattcttg tcatagtagc tcagctggat
    46801 agagcatccg ccttctaagc ggacggtcgg gggttcgaat ccctcctgtg acgctaaaaa
    46861 accgttagaa actgaggttt ctaacggttt ttctttgttt tttgtgccaa tattgtttgt
    46921 tttcaaaggc aaataaaata aaaaaacatc cttatcgagt acaattataa ggagcaaaaa
    46981 aataaaactc atcagaaaag aggaagaaga tatgacgata ctatctagaa ttttagtgac
    47041 tctagttgca attgaatttt tttatatcat gtatatcgaa acggtgagaa ctgattctga
    47101 cacgacaagt agggttttta aaatgagtaa agaagagtta agcagaaaat ctgttcaaac
    47161 attgtttaag aaccaaggag tgtacaatgg actattagga gtgggactac tttatggagc
    47221 ttatctttct tccgcatcta aagaaatcac aagtatgcta ttaatatcta ttttttttgt
    47281 tgcattatat ggcagtttga ctagcgatcg ttggatttta ctcaaacaag gtgggctagc
    47341 tctgttggca ttgctttcta ttttcttata aatatagaaa aaataagaat ttatctaaca
    47401 ggaaactttg tgaaaaatat tactttatct catgaaatat gatattctaa tgaatggtat
    47461 tttagaaaat ttcatgaaaa aggagttaga taggtgttca aaaattatgt ttcctcacta
    47521 aaaaaagaat tttcaggtta tgatctttca agatttcaga aagatctttt ggctgggatc
    47581 acagtagctg ctgtagcatt gcctttagcc ttggcttttg gggtatcaag cggagctgat
    47641 gcggccgcag gtttgattac ggctatcatt gccggtatcg ttattggcgg tttatcaggc
    47701 ggtttttatc aaatatcagg tccgacaggt gcgatggcag ctatcttgat gtctattgcg
    47761 gcaacaaagg gaatgcaagg tgtattgctt gctacttttt tagcgggtct atttttactt
    47821 gcagcaggac ttttccgatt aggaacactg acttctttta tcccagcacc cgtaattacg
    47881 gggtttactt caggtattgc tatcattatt gcattaggtc agatcgataa tttatttggt
    47941 gttcactcgg aaggtacaaa cgttattgaa aaactaagta gttatcaaac gataggattt
    48001 ccgataaaca cagcctcttt gatcatggga gggctagtca ttttagggat gtttatctat
    48061 ccaaaaaaat gggcgaaacg aatgcctagt tcgctgctgg ctatcatttt ggcaacagca
    48121 gttatgctat tgttccattt accagtagca actgtgggta agattccaca aacattgatc
    48181 agtagtaatc gtttgaatat gggagatttt agcttttctg ccttgcaaca agtggcagtt
    48241 ccagctatta gcattgcttt attaggaatg attgaaagct tgctatgtgg tgcttcggct
    48301 ggccgaatgg caaataagcc cttagatagc aatcaagaat taatggcgca aggaattgga
    48361 aatctgttgc ttcctttctt tggcgggatt cctgctactg cggccatcgc ccgtacaagc
    48421 gtggccatca aatctggtgc acaaactaga ttagctggta tgatacatgc agttgtctta
    48481 ctgctctcca tgcttgtttt tgcgccagtg atgtcacaga ttccaatgcc agcacttgca
    48541 ggtgttttga ttgtgacggc ttggcgtatg aatgaatggg aaacgatcaa ggagctattt
    48601 actaataaat attggtcagc agttctattg tttatcctta cgatgatttg tacagttatc
    48661 tttgatttaa gtattgctat cgtgatcggg gtgatcggcg gctgtgtatt ttttgttgtc
    48721 aaaagcgctg ctatcacgat ttcattagaa acgatcgatt ggcaaagaat ggggctgcca
    48781 gaaacggaaa agctgaataa ctggacagta gtgtatatta gtggtccact gttttttatg
    48841 tcttcagaaa aactcaaaaa taaattggaa gaactaaatc atcacgatgg tgtcattttc
    48901 tccatgcgag gcgtaccaag tattgatttg acggcacgtg cagtttttga tgaatttcaa
    48961 gaaaaagcag agcaaagagg acaaacgatt atctatactt ccttgcagcc agaagtagaa
    49021 aaacaacttt ctcacttgtg ggaacataca ttcacgcatc aacatcaaac agttgctcat
    49081 gcgttgacag ctttacatgc gaaatatact gcaattagcc attaaaacaa tgaaaaagaa
    49141 cagacaagac tgtaaactga agattttatg gtcttgtctg ttctttttaa tattgctgta
    49201 aaagtgaagc tagtacttgc cagtcttgat ggataacagg tacaagggag cgattgtaga
    49261 aaatagctgc tggatgaaaa agtggaagaa ttcgatagtt tttttctgac cattcgtagg
    49321 catccttttg ttctgttaat tgtaagacag gccctgtata gagttgacca tgatttttgg
    49381 taaccgtata ttctttgcca agtaaacgtt gaagaccaat gtttccaagt gtcgcaatta
    49441 attttggctg gaccttcatc agttcgtaat ccaatattgg tgcatgcgca aatacttcgg
    49501 aacgagtagg tgtccgattt ggataaacag tttctgactg ttgtgtccgt ttattgatcc
    49561 gatgagtcac gcgatacggg cggctcctta cagcactggt gatatacacc tcttctcgtg
    49621 ttaagccagt tgaagaaagt gcctgcatca attcttttcc agcttgaccg ctaaaaggaa
    49681 catgcgtatc aatctctgtt ttccctgggg cttctcccac gagcatcagt ttaggatgaa
    49741 gaggtccttg cccagcgata aatccttcta caggacggcc gttcattctt aaagaagctt
    49801 cttgtatcag ttcttttggg tattccattt atgctcctcc tttttctttt attataagaa
    49861 taaaagaaac acaatgcgac tattttattt ggtagaactg tgaggataga aaagcagaag
    49921 tattgcttga atttttgttt tactttttga ttttaaattt agttgactaa cggttgctgt
    49981 tctggtaagc tagtactgtt gtaattgtgg actccacagc tacaaccgct cagaacaagt
    50041 aataagcaca gcatatgctg tcacttcgga tggcgagtct aagtatatca gaaggaggtg
    50101 ctttatagca tgtacgcaat tattaaaact ggtggtaaac aagtaaaagt tgaagtggga
    50161 caagcaatct atgttgaaaa acttgacgtt gaagcaggag aaaaagttgt ttttgacgaa
    50221 gttatcttag taggcggaga atctacaaaa gtaggcgctc caactgttgc aggtgcaact
    50281 gttgaaggta ctgttgaaaa acacggcaaa caaaagaaag tcgttacttt caaatacaaa
    50341 cctaaaaaac attcacaccg taaacaaggt catcgtcaac catatacaaa agtggttatc
    50401 gacgcgatca acgcttaata gcgtttgaga aagaaggcct atatatgatc aaaggaacat
    50461 ttaagcgaaa tgacgcaggt cagatcgttt cattcacttt gaccgggcat gctgatgctg
    50521 gtccttatgg aagtgatatc gtttgtgcgg gtgtttctgc gttagcgatc agcactgtca
    50581 acgggattgc ctcattagcc ggttttgagc cgattgttga aatgaatgaa gaagaaggcg
    50641 gttatcttta taccgaagtc acttcaggaa tgacacaaga acaaaacaat attgctgaga
    50701 ttctattaga aaatctttta ttaggattac aatcgataga agctgaaaac tcagaatata
    50761 tccaaattaa aacaattaat gataaatagg aggtgcagac catgttgtta tctatgaatc
    50821 tacaattatt tgcccacaaa aaaggtggcg gttctacatc taacggccgt gactcagaat
    50881 caaaacgtct aggtgctaaa cgtgctgatg gacaaacagt tacaggtgga tcaattcttt
    50941 accgtcaacg cggtacaaaa atctatccag gtgtaaacgt gggtatcggt ggagacgaca
    51001 ctttatttgc aaaagttgat ggcgtagtac gtttcgaacg taaaggccgt aacaaaaaac
    51061 aagtgtctgt ttatccagta gctcaagaag cttaataaat aaactgctct atctcttgtg
    51121 tagcaaggga tggagctttt ttgtaaatta tgggattttt tttgaccata cttttgacca
    51181 tactttctta gaagttaata taatttgtta gtttttgtgt tgtttcttct tttttgctgt
    51241 tagtaatgtg tgtatatgtg tccatagtag tttttatatt tgcgtggccc attctttctt
    51301 ggacttcttt gtgatctgcg cctgcctcat atagcattga tgcatgtgta tgtctaaaac
    51361 catgcagacc gatataaggt aagccggcac gctcacgata tatattgtat ctttctgcca
    51421 ctgactgatt aattgtgaaa ttattttcgt cattggtaaa caaataatta gctttagtaa
    51481 atcctaattg aaataagtac tttctttgtt cgagcttcca aaattttagt tgctttatag
    51541 ttttttcatc taaataaatt attcgatttg attttttggt tttaggagtt tcagatatat
    51601 aatatttatc tgaacgagct acagtttttt taatggccat ttcatttgtt ttaaaattaa
    51661 tattgtccca agtgagtgct aatatttcgc cgattctaca tccgctgaat gctaatagtc
    51721 taaagagcgt atagtctctg tttttaaaat atggattctg ttcttgagat acttcattta
    51781 gaaataattc caactgttct tttgtatata attttaattt cttttctgtt ttaatttgtg
    51841 gctttggaat aagtaaattt aatgttggat tatcagatgt taaaccaata tttatagcat
    51901 acttaaaaac tttattcata tagtttatga aaagagggta ctgctttgaa gttccttttt
    51961 cactccaatc atttactacc ttttgacaat atgccgtatt aattttagaa agcttaatat
    52021 ttccaaattt gggatatata tgtttattaa agattatttt agtccttgaa tatgaacttt
    52081 cttttacagt ttttttgtag ctttctagcc ataattctgc tgcttctttg aaagtagtat
    52141 ttgtacttgt gggcattcct gttttttgta attctagttc taacctagaa agtgctgttt
    52201 ttgcttcttt ttgtgttcta aatcctcgtt tagtagtata ttttttcttt ccagttagcg
    52261 gatcaatacc gagataagtt ttaaagtacc atgctttttc gccatttttc tttttatatt
    52321 gttttatcat tgccatcaat attaccccta ttcaaattct aattctgcca tgctatcatt
    52381 gaaaaattcg atcagtcctt gttcctctat aaattcaagc catatttcct tcccgttaat
    52441 taatggaact cctttttctt tacgaattgt ttgatacaag ttagtcacga cttgtttcca
    52501 catttctaat acagctttat ctattttctt atcatcccag cgtttttttt ggggtctatt
    52561 tttgtttttt tcaatttgat aattagtagc tttgatgata aatgtttcgt atccggttgt
    52621 gcttttttct aaccattctt tgaattctgt atatatcatt tttgttcacc tttctatttt
    52681 tgaacgtatg ttcttttttg cttaaaaaat tttagagagc tgcataacaa tagatgcgag
    52741 cttttaataa ttctttcaca agtggttcga agcgaacgct taaattgtta tcttctataa
    52801 atttcatgta attgatattg tgtggttcta attcagactt tgcaatatat ctatctaata
    52861 atttttcaat catgaagcga tcagcctcat attccatttt tgaatggaga gagaatgcta
    52921 agttatataa aaaataatta tcatgatgtt tagaagcgtg tcctaattca tgtaataagg
    52981 ttctttgtct tctatactta gataaattag cttttattac tatggtattc atacaagcaa
    53041 cataatggcc atcggcatca aggttttcac gctcttctac cttaacgccg agttcattaa
    53101 ttatcatttc aatttgactg tccaaatgac tcacctactt atttagttat cttttttctc
    53161 taaatatgct tcaatcatag ctgatagtat ttccctatca ttatcggtga gcggttttcc
    53221 gtcgctactc ataacagatg ctaaagcttc ttccacggtt agttttcttt cctctggtgc
    53281 aactcccgcg ttaggatcat ctgtgcgtcc tagcaaataa tctgttgata catggaagta
    53341 gtcagcaact ttttgcaaag tttctatttt aggactttgt gtcttccatt tataaataga
    53401 gttttttcca aatcctattc tattttctaa ttcagaaata gaaatacctc tttttttaca
    53461 gagctcttta accctttcga aaagcatgtc aaatcaacct tcctagagcg tacgataata
    53521 atttatacaa aaagatagaa aggtagttga caaatctatc caattgtctt atatttaact
    53581 cgtaagctaa tttaataagc taacaagcaa caagaaatac acctaataaa ataaacgaat
    53641 tcgaggtcgg caaactaaga atgttaattt ttagggtttt tctaggctta tttaactgta
    53701 tataaatata agacagttgg atagaaatgt caataaaaat tagctaattt tattagctta
    53761 catatttaaa gaaaaggagg aaacatcatg aaacaaaata aaaaaactcc ttccgcaaaa
    53821 ggagctttaa taactttaaa ttttaaagac caaaagttta gtgctgttgt tgatgaaatt
    53881 catccacaag agcatcaaaa aaattctttt gcaactgacg agaaaaagac tcagaaacgc
    53941 tctgagaaag ttcttcgaat aattcaattt ctgttggaaa agattcgtca ttttggaagt
    54001 ctattttgaa ttctttatta acagtcttga atacggtttg tttgaataag gcgtcgacat
    54061 ccatattaaa ttcttccata ctattttcac ctcgctttct attcaaaatt atatcaaaga
    54121 aaggaatgag caaaaatgaa cacaccgcaa atttttaact ttgaacaaca tgaagtaaga
    54181 acagtaacaa tacatgatga accatttttt gttggaaaag atgtggctaa agttctaggg
    54241 taccaaaatg gtagtagaga tattaacaga cacgtcgatg tagaagatcg gcaaaactac
    54301 caaaacggta cttttgaatc gcctagaggg ttaactatta ttaacgaatc aggtttgtac
    54361 tccttaattt taggaagcaa acaaccaaat gctaagaaat ttaaacgttg ggtgactagc
    54421 gaagtgttgc cagcaattag aaaacatgga ggttatctaa ctccagaaaa agtagaagaa
    54481 gctttgctta atccagatac aatcatccaa ttagcaacta agttgaaaga agaacgtact
    54541 ggaagactaa tcgcagaaca aaaaattgca gaatacgaac ccaaaatttc gtatttggat
    54601 agtatcttat cttctacaga ttcagtaact attagtcaaa tcgcggctga ttatgggatg
    54661 tctccacaac agatgaacaa actacttcat aagctaggta ttcagaaaaa agtaggcaac
    54721 caatggttat tatgcaaaaa acacatgaga cagggttaca caaaatctca tacaactgag
    54781 attccgaaat ctgatggcgg aacaaaagtt gtgatgaata caaaatggac tcaaaaaggg
    54841 cgtctgttca tttatgagtc gctgaaaaaa gaaggatata ttccagaaat cgatttatta
    54901 gaggaggaat gacgatgtca caagaattta ttttgaaagt cagaattcaa ttagcaaaat
    54961 acggaaagtc tcagaactgg ttagctgata ctatcggaat ttctagacca tatatgtcgg
    55021 acattatgaa tgggcgtaga aaaccagata aacaaatcaa gccaattgag gcagcactag
    55081 cagagttaga gaaggagaaa taacatgcaa ataacaattc cagataattt agtagtttcc
    55141 gaattaacta cacagattac gaatgctgtt cttaattcat tggacgaacg attacacctt
    55201 atgaacaaat cagtagagct tcctccatat ccaaacaaat cagaggtaaa aaaagtttta
    55261 ggcattggtg atgacaaatt aacacattgg ataagcctag gcttaaaaac acagcagtgg
    55321 agcaagttag acatcagaat tgaacgatcg gaactccaaa gatttttgaa agaaaacttt
    55381 gagttctaaa ggcaaaggag aatgatttta tgtcctacac attgcaacaa gaacatcaaa
    55441 ttctaggtct gattaaacag cgtagaaaac aattacaaga tgatcgtgca gcgcttagaa
    55501 aatccgatga gctatcagat agacaagctg aactaattgc ttctgaactt gaggatttga
    55561 gaatgctaga aataaaaaat agggagatta gattatgaag aagacagaca cactttttat
    55621 aggattcatt ttggggttat tagtgattgt agcgcaccaa agtattatcg gaggaagctt
    55681 gttcgcagca ttgatggttt taatcaatct gcttgactca aaagaaagga gcaactatgg
    55741 cacgagaaga agcgctaaaa atcggtaaag tgattgctga taattggtgg gcaaatagcc
    55801 gttctattat tttaagcaag caacatatcg aaaagaaaaa agcatggcaa caaataaaaa
    55861 agtgactccg ccgaccaaag caatgagtca ctcaaaaaat cataactaag gagattttaa
    55921 catatggaaa atgaactttc cactctagat caatatttgg ccgatcctga ttggggcaaa
    55981 tcgaatttac aactggttgc taacaagtac gaaaaatcaa ttgatgaagc aattgttgca
    56041 ttgactgatg cagcttccat aaccgctgat gacagtaaat ggaccaagag agacttgggc
    56101 attctaaaac gaggcgttaa ttggcttgaa gatcagtaca gagaagaaac aaaagagaag
    56161 tgatatgagt gtttaaacca ctaatagatt catactcggc ggtactaaag aaatttaaag
    56221 gtaacgacat tggtgcaaca atcaacgaag aagtaaatat cgaacggctg aaaacgatgt
    56281 atgacggata tgatggcgat cgagtcattg aaattcgctt tattgatcca cgacggttca
    56341 cagtacagca aagaaacttc atctatgcgc tcataggcga tattttcatc gatacaggca
    56401 tgccaacgga cttctggaag gaattcttct acttccgttt tgaaggtgtc acagggcgcg
    56461 aaataagcct caaagacgaa tcgaatacaa ccgtgagtga tgccaatatc ttagcgaata
    56521 tcatcctaga tttcatcttt gaacatcata ttcctttcaa agaaggatat gagattttac
    56581 cagcgaatca agagtattac ttctacaaat gcattacaaa aagagtctgc tgcatctgtg
    56641 gcaaaacagg agctgatatc gatcactttg acaaagcgct gggaagacga aagcgcaaag
    56701 aagttgatca ttcagagtac acatttgcag cactctgcag aatccatcac acagagaaac
    56761 acaaaatagg tgtgatcaat ttcaaaaata aatatcaaat caaagggatc aagttaaacc
    56821 aggaaacaat taaaaagtta aggataggag gataaatttg gctgagataa gttggatcaa
    56881 acttaaaact actatgtttg acgatgaaaa aatacgatta atccaagctg ttcctgagtc
    56941 ggatgccatc atcgttatat ggattcgatt actagtttta gcaggaaaga ctaacgacga
    57001 tggtctgata tatatccaga ggaacatgcc ttataccgaa gaaatgcttg ctacattgtt
    57061 tggcaaaaac gtaaatacgg ttcgcttagc gctaactaca ttggcaaatt tcaacatgat
    57121 tgatctaagc agtgatggac taattgccat cagtaattgg gaaaaacatc aaaatatcga
    57181 gggtatggat aaagtaaggc taaaaaatgc tgaaagaaac cgtaaataca gggaaagaaa
    57241 gagacaggaa cgtctcaaat tggaaaatga cgttagcgtg acgtcacgtg acggtacaga
    57301 taaagatata gaagaagata aagatataga taaagaagaa aagaaaggta agtattctga
    57361 cgaacactta cgccttgcta aaaagttgca aagtaattta actgaagatt ttccaaaaga
    57421 aatgaacaaa gtagatatcg aaaaatgggc agacacaatc aggttgatgg aagaaagaga
    57481 taaagcatct atagaagcga ttgagtatgt gatcaattgg ctacctacaa atgaattttg
    57541 gtttggaaat attagaagtg ctaagaaatt gagagaaaaa tttgagaagc tcaaattcga
    57601 aatcaaagca gacaagaaga atcataaaaa gcaaagtcaa aaactacagt acagcaatcc
    57661 tagtgaatat gacgacttgc caatttaaaa aggagatgca tcacatggaa agcctagcaa
    57721 atgctatgga gaaactaata agaagagtat tagtgcaaag cggaaaatgt ccagaatgta
    57781 gcgaaccttt gtatagttgg cgagctaaaa ataaggatgg ttcagaacgt tgtaaaccaa
    57841 catgcatgag ttgtggttat aaagcgttac gtgtgaaaga ggatatacag accgaacgga
    57901 tatataacga tagcttaaaa gcacgagcgt tgagtttttt tcaaaatggt tcggtattaa
    57961 cagataaaac tttgtttaaa tgcaaaatgg aaaattatca cgtagtggat caagaaacaa
    58021 aaatcgcttt agaaaaagca aaaagctata cgaatgaggt tctgctgaac catcctgcac
    58081 atttcattct atcagggaaa tcaggaagcg gaaaaagcca cttatcaatg gccacagctt
    58141 gggaaatact tgagcgctca aattatgaca agaaaatact ttttataagc tatcaagaat
    58201 tattagagca aataaagttt tcttataaca atactgaact gagaaaagaa attgaaggat
    58261 cgcttatagc cgatattaaa acaactgatt tggtggtttt tgacgatatt ggagctgaat
    58321 taggtagtgg ggtatcaaat agtaggcagt ttacaaacaa cacgttaaac acgctcttag
    58381 aagccagaca gaacaaggca acgatcatca caacaaactt atctggtcct gaactaagag
    58441 aagcctacgg tgaaagaatt gtttctagga tatttaagaa ttcagaaggt tatgcgctga
    58501 aattccaaca aacagcagac aagcgcataa aaccagtgaa aggtagtatc gcatgaataa
    58561 ataccgtaat aaaaaaactg ttcatcgagg tatcaagttt gattctatcg cagaagcaga
    58621 gtattacgat ctagccttgt ggcaagctga agcaaatggc tggaaagtaa aacttcagga
    58681 aagatttgag ctgatgccga aatttgaact agacggaaag aagtatcgca agatcgagta
    58741 tattcccgac ttcacatttt ataaaaacgg caaacttgtc aaagtcgtag atgtcaaagg
    58801 aatgcagaca aaagacttta agatcaaggc aaagttgttc tgtcatcaat atcaagcgcc
    58861 gttgatatta gctaaaaaat atcggaatac gttcaaggaa gagcgttttt aacgaggtgg
    58921 tccatcatga caacagaaga agtgattcaa atgcgtattc gaaacattca gcgtgaaatt
    58981 gacgatctag aacgaacaaa ggcagtgatg gtcaatgaaa cggcgagaaa ggcaatcgat
    59041 ttgcacatag agaacttaag aagggaaatt cgtagattgg aggaatgagc gtggataaga
    59101 aagcgacaat gaaacgaatt gctgaattaa ccaagtcaga atcttggcag gaagacaaag
    59161 aaatagttgc agaagtccaa aagctcggta aatcaatgtg gactgaaaag cctaaacgga
    59221 aaacgccgag aaaaattgca atctggcatg gtgatcgaat tctagtaaca ggtacagctg
    59281 aacagttatc tgaaattact ggattaagca aaaacattat ctgggataga gctaggagct
    59341 tatggattga ttcaaaagga cgacagttta ggtatgtgga ggagagataa tggatctcat
    59401 tacacaatac agtgacatca tcctcaagaa aatcatgatg aagattcaga aagacaaaaa
    59461 atcaaaagaa cgagctgaat tagttaagtt agaaatggct gaaacaggag caggagtgcg
    59521 aagtagcagg cattggaaag cagcagcaaa cattgaattt tattacaacg aaattcaaaa
    59581 agggttcgat cagatgcgtg agctggatcg gcaaacaaat tggagcaaga aacttcatca
    59641 agatcgtttc aaatttgtag agaagtataa agaaatatta gaagagtatt tgaggaggac
    59701 agcaaatgat aaaaaaactc gttcaattca gcatggattt atatgatatc gaatcaggag
    59761 caacactatc tgtggaatcg gaccatctaa tcataaattt tggtggaaag cgccagatta
    59821 ttttgtgggt agttgatgat gtactgtttc cagaaattgt tcatgatttc gaagaatcaa
    59881 aagcggttga gtttgaaata gtgaaaaaag taatggaatt gattgaaaaa tacgaggagg
    59941 acagcgaatg ataccgaagt ttagagcgtg ggatagagaa aaagacagaa tgaaggcagt
    60001 agctttggtt gaatttgctg aggcgtataa atcaggagaa ctcatttcac gtacaaaata
    60061 aaaaaagtcg gattcctccg actatgaata atatttccga cataagtatt atatcataat
    60121 tgggggaatc agaggatggt acttttcgat gtaaagaaat atgagacacc aagcgcgaaa
    60181 gatgttgata tggaacgcac aaaacataat gtcgctgtgt ttctttcagc atatctatca
    60241 gctagatgta gagtagggca acctcgagaa ccaaaagtga cagcatctta ttccttggtt
    60301 ccaccttcta cagctgatca tatatttgaa gcagaaagaa tgctgatcga taaagaagaa
    60361 gcacaggaag aatttgagta tctgcataaa ttgtttgttc gaggctattc agcgatacag
    60421 catccgcata agcctgatgt gactgaaagg cgcaagaaga tattctatga tcgttatatc
    60481 aatggtctgc ccatttatgt aactgctcaa aggaataata ctagcgaaga atcggttaaa
    60541 gtagaatcaa acagaattat catccaattt gcttcatcgt tagaactggt tgctttcaag
    60601 tagccagttt ttacactttt tatacccttt tattaccaat ttggtttcca ttttatacct
    60661 tttttatacc aatcacttac ctattcaacg ttgtattatg atagtgtcga aagattagga
    60721 aacaggatcg acaaaataaa atgtaaggga ggaaatctcc ctcatcgttt aattaagctt
    60781 cgataggcag cagcggaaat attaagaata aggatgtgaa tttcaactcc ttctaaattg
    60841 ttcttattat ctatcatccg ttgctgtcta ttaatttatg tattggaggg tatataaaat
    60901 gaagatcgct tccgaaaaaa ttgatcaact aacaatttta gtaaaccaaa gaatcgaaga
    60961 tattatcaaa gaattcgaag gtgaaaagat taagaacata aagcttactt taatggatca
    61021 taagttcgaa ttaaattcga caaaaaggaa gatcgttgag cttatagaag aagaaatagc
    61081 tctccagatc aatgagcaac aattagctaa ttaatttatg tattggaggg gaaatgaatg
    61141 gaagtcgaac aaataaagta tcaaggtatg gatcgggaac ggttgattga tattattgag
    61201 caacaacgtt tagaattgat ccaaaaagaa gctgtatgta aagagtacaa aaaacatttg
    61261 gaacaagtaa ttgagtatca ttcagtagaa aagtacagat cagtggtgca aaaaaataga
    61321 gcaacgagtc ctgattctcg tcaagatgta tcgattagta tcaagacgcc agtatttaat
    61381 tctgttaaat cagaaaagct agaaagtatc tcaactgctt tggtagaaaa agcagctgaa
    61441 atgaactccc tagcaaatga agttagtcgt cttatttagt catatcgata acttgagagt
    61501 ctttggtgat tccgtttttt atagaattaa tggtttgttc agcggaatat ttagtcaagt
    61561 atgtttcgct agttgctact acttcattgt tattggactt aataacgaag taatattggc
    61621 cattagttgc ttctcttata acaaagtaca aatttttcac cacctataat ttatttcagc
    61681 ggaccactcg ctgataatta aaattataag ctatgtataa aatttcacaa tatcaatttg
    61741 tcgctgtggc ggaaagggta gacgcaataa aggatgaatg ggaaaagtca atgagtaatt
    61801 atctgaaatt tacaagtccc ctgtttagtt atctaagatt atttgataat attatttctg
    61861 aggtgataga aaatggtggg cgtagttaaa tttcttgggt ttacatttga tggatatggt
    61921 acgttaggcg aatgggtagg tattattttg atagtgatta caattcaaca aacatcaaag
    61981 tactactggt attctaatag ttctaaaatt gtatcaagaa taactgaagg aataaccaaa
    62041 aaagatatta ctgtcgtcgg taaatatggg tttactataa ctttattaaa tgaagggaaa
    62101 tctgaaaccg caataaagtt ttgcgggatt ataggtaaat ataacatttt ccaacgtttt
    62161 atcagaaagc attggtacaa atatatttac aaataccctg tagttaaaaa gcttattgaa
    62221 aaatatgtgg accacgaaat atcttatctc aatccaacag accttattaa tcaagaattc
    62281 cagaatattg gatacttaga aaaaggtcta aaaataccaa ttgtaaatga aagtttagtt
    62341 actgcaatgg tagctaacat aaagaacagc aagaaattag aaaagagata taaaaaatgt
    62401 aaaaaattga aattttcctt tttattctta gaatataatg gcaaagaata ttatcaagat
    62461 atttatgttt tgcgaggctc gaacttatat aaagacatta aaaataagat ttcagtatga
    62521 gattttttaa aattcgtaga tcactctttg agtggtcttt ttattttgcg taaaggaggc
    62581 acgacgatgt atagaccaca atacttagaa cagaagcatg aagtaatcac tgtgcaaaac
    62641 ggtaacggtg agatagtacg aaagtataga agaccaataa agagcgatac atataaacgg
    62701 aaggaaagca atgaagttat tccattgtat ggcaaaagaa tagctaagta ttaaataaga
    62761 ttgcgaaagg agatgggaca tgaccgagga attctataga tggttattac agttgataag
    62821 agaagatcgt ttggttaagt tctatcagtc tcctaaatgg cgcaggctta gagagaaagc
    62881 gatgaaacga gatcactatg aatgccaaga gtgtagaaga ctaggtaagt atcatagagt
    62941 agagaacgtt catcatataa aggaagtcaa ggatagacct gacttagctt tagatttaga
    63001 taatcttatt tgtttatgtg ttgaacatca taatgaagtt catggcagat atcttacagc
    63061 gttagataaa caagagaaga agatagaaag cttcgctaac ttcgatgcaa gtgaaaggtg
    63121 gtaagtgcat gatcatcaat gacaatggca gagagtatga tacagaaaag attgaagagt
    63181 attcatctta tactcaggga ttaattaaac gtttgatata cgttcgctat gtaggtatta
    63241 gggatctgtt atcagataac tgttgtagta aatacaaagt gaatcaagta agagaagcgt
    63301 tgaataaaga taataacgtc gaaagaataa aaaatgtttt tggatatagt attgaagaga
    63361 ttaattatta cattgacttc gctgaagctt tcattccgat ggtgagataa ccccccctta
    63421 aaataaatcg caaatttttt gggggtgatg aaacggaggg ggctgtcagg aaaagagatt
    63481 ttttcgaact ttatcatgaa aggagggcta aaatgtttaa aaacgaattg tctcaaaatc
    63541 gctacagaga aaaattacgc cgctctttaa taagccaatt ggaaagtcag aaaacaaata
    63601 ttgagccatt cttagataat gttgatcgtt atatcagttt atgggaaacg gcgatatcac
    63661 tggaagaaga tatatccgag aacggcatta gactggagaa tggtaaaaag aatgaatcag
    63721 tagcgttgct tgtttctgtc aacaaacaaa tgggattgat gttggataaa cttgccatta
    63781 ctcctgaatt ggtaggtgaa gcaaatgaat caattcctga gttataagca tattgaaaat
    63841 tggttcaaag ctatagaaga aggcactatc aaggtatgca aagagcaatt attgctaaaa
    63901 aattatctag aagaaagagt ctttactaga gaagatattt acttcgataa gcagatggta
    63961 gaggattcaa tcaatatacc agcacaatac tttccattcg aattaattcc gtgggaaaaa
    64021 tttctacaat gttttattta tggtgttcga tggaaaaaag ataaaacact agtgttcaat
    64081 agatatcttt cattaatggg acgtggtaat ggtaaaactg gttttgcttc ttggaacaac
    64141 ttctttctac taaccgctaa acacggtatt aaaaattatg atattgatat ctatgccaat
    64201 aatgaaagcc aagcaaagac tagttttgat gatgtattta aagtaattaa agatcatcct
    64261 gatttagata aaaaagtatt taaagctacg aaggaagtta ttcaaaatat cgctacaaac
    64321 agcaaacttc gttataacac ggcaaatgct agaacaaaag atgggaagcg accaggtgca
    64381 aaccgctttg atgaaattca cgaaaatgaa gattattcaa tgataaatgt ggctacttct
    64441 ggtggtggta aaattcgaga ttatagagaa ttttatgata caactaatgg tcatgttcgt
    64501 ggtggtccgc ttgatgacat tatagaagaa tcaaaaatga ttctttctgg agaacttgga
    64561 attgacaagg atggagcaga attttctagt ttgtttccat ttatttgtcg cttggataac
    64621 gataatgaag ttgatgatcc cgacatgtgg gaaaaagctt gtccaactat taattacaat
    64681 gcagatttaa aacggaaaat gtttcaagaa tactctcaaa tgcaacgtaa tgctggttta
    64741 agacttacgt tcatgaccaa acgaatgaac agacctatgg aagatacacg atttgctgtt
    64801 gcttcatatg atgatgttct gcatacgaaa gaaaaagaat ttcctgaaaa aatggatgaa
    64861 gtgataggaa cagtcgattt tgctgataga cgagattttg ccagcgttgg gttgctagga
    64921 aaatacgata aagatgttta ttttacacaa catactttta tccacgaatc agcccttcga
    64981 ttacaaaaca tcaaacgaga ggttatagat atttctatag atcaaggaaa atcacagatc
    65041 gttcatggaa aaaatataga agctgattat attgtaggtt ggtttcttga aatgagtaat
    65101 aaatattata ttaaaaaaat cgctatggat atgtaccgtg caaaaatatt gaagcccgct
    65161 ttagaagaag caggttttac tgtggaaatt gttcgaagcg gatctgttac acatggtatg
    65221 ttaaaagatc tggttgatga cctttttatt aatcaacgtt tattttttgg tgacgatgcg
    65281 attatgcgtt ggtattgcat gaatgtatat gaagagcata tttctaatgg aaatatacgc
    65341 tatgaaaaaa tagaacctga aactagaaaa acggatggct ttttttcatt ccttcatggt
    65401 ttgaattttt tagatgatat ttatgattct gctcctgtaa cagtcacaaa tagctcagta
    65461 gaaaatacag gaactggatt tactcctcta gtattctaac ttgaaaggag gtgagaaagt
    65521 ggggattttt caaaaggcgg taggatactt cacaaaaaaa gcaacggttc ctttagaaga
    65581 atacttttgt aaattgcaag ttgattttgt gtatcgaaaa tttgcgattg aaacttgtat
    65641 tgatttgatt gcaaatgcga tgagtaaagc ggaattcaag tcatatgaag atggaaaaaa
    65701 taaaaagaat gatctttact ataggctgaa tgtagctcct aataagaaaa ataatgcaac
    65761 agaatttaga aaaaaactga tcaggagatt aatattctac aatgaagtat tgatcgtttc
    65821 tccgtctaat aattctagcg aaatatttat tgcggatagt tgggatgtca cagaatatgc
    65881 attgaaagat gatgtgtttt ctcaagtgca aattaacaac atagtccttg atagagaatt
    65941 tctagaaagt gatgttatct atataaaata cgcagatcaa caaattaggc aactagtcga
    66001 tgcgtattat caagcgtatg ggaaactcat ttctagtgcc atgaatgttt acaagcgctc
    66061 taacgctcgt agatacgtac tgaaagggaa tttattccga ccgcaagaca atacaacaca
    66121 agatcaaatc aataaaatga tgacatcaca atttaaggct tttatggaag ctgataatgc
    66181 aggtgcggta tttcaattac aaaatgagta cacattagaa gatttcagcg gaaacttcca
    66241 aagcaattca agagatataa aaaacttaat agacgacatc tttgagatga cagcagcagc
    66301 gtttcacgtt ccgaaaaacc tactaaaggg agacatgagt gggttatcgg atcaagtgga
    66361 cgctttttta atgttcgaaa tcataccgat tgctgaactt attcaggatg cgtttaacgc
    66421 tagtctctat gaagtagaag aatacttgtc agggaatttt gtacgtgtgg atacaactat
    66481 gatcaagatt actagcttca aagatttggt tgacgctatt gatgtaggca ttagaaatgg
    66541 agtatttaca atcaacgaag gaagagagcg cgttggaaat gatcgctctg ataaggcgat
    66601 ggcagatgaa atatttataa ctaaaaacaa tcaacaagta tcgaaaggag gtgaggcgaa
    66661 tgacgacaat gaaaacattt ctagcagtaa agaatgaagg cgcagtaccg caaattttta
    66721 ttcagggatt tattggttct agttggttct ttgaagggaa tactgacaag ggaatcaaaa
    66781 atattttgga tagtctaggt gatcaagaag aaattgaagt agtaattaat tcaaacggtg
    66841 gagacgtatt tcaagggatt gctattggga acttacttaa gtcaaataaa gcaaaagtta
    66901 acgttgtgat taacggctta gccgctagtg ctgcttcaat tatcgcaatg gctggcgata
    66961 ctataaaaat ctacaacaat gcacaattga tgattcaccg cgcttccaca tacggagaag
    67021 gaaatgtcga tgacttccgt acgattgctg accaactgga atcaattgat aaatcggtaa
    67081 aggcttcata taaaacacga ttcaatggca cagatgaagc attgcaagaa cttcttgaaa
    67141 aagaatcgtt tatggatgca gaaacagctt tgagttatgg attggtcgat gaaattatcg
    67201 atgcagaaaa tagctcaggt actgaagcta aaaaagaaca aagcgttgaa gaaattttga
    67261 atgacgttaa agaaaaaaga gcagaaaaaa ttgctgcatt tacagcagca ttaaataaaa
    67321 catttggaca aggagatgta aaataatgac agttaaaaat ttaaaaggtg taacagctgc
    67381 aagcgaccaa ttgatgaaag cttttaaaga tggtaacgaa gaatctttta gcgcagctat
    67441 ggtaagctta tctaaggaaa ttcaggataa aattttagaa gaagcaacag caaaaaatca
    67501 agatcaatta gtattaatga accgtggtca gcgtgtatta actacacaag aaacaaaatt
    67561 ctataacgaa gtagtgaaaa acgaaggttt tgcaggggtc gaagaattag tgccagctac
    67621 tgtatttgaa cgtgtatttg aagatttaga acaatctcat ccactattgc aaaaaattac
    67681 ttttgttaac acaactggtg taacagaatg gattgtgtca cgtggagtca atccagcatg
    67741 gtggggtaaa ctttgcgaag ctgttaaaaa agttttagat aatggctttg atgtaattaa
    67801 catgaagcag ttcaagctat caggttatat tcctgtatgt aaggcaatgc ttgatttagg
    67861 tccagtatgg ttagatcgtt atgtccgtac tgttttagta gaatcattga gaattgcatt
    67921 agaacaagca attgttgatg gtactggtaa agatatgcca gtcggaatga tgcgtgacat
    67981 gagcaaacaa actagcggag aatatgctga aaaaaaagca gaacctatta cagctttaga
    68041 tgctgtaact atgggcggtt tgatggcgcg actatcaaaa ttcaatatcg aaggtgtgaa
    68101 tgatccgatt tatcgtaatg tgaatccttc tgatgtggtc ctaattgtga atccaactga
    68161 ttactggtct aaagtattcc cagctaagac tgtactaact gctaatggag aatacgtaca
    68221 agtattgcca gtaccagttt cagatttgca gtcaacggct gtgccagaag gaaaagcagt
    68281 tattggggta gcctcagatt acttcatggg tgtaggatct acactaaaaa ttgaagcttc
    68341 agatgaatac cattttgttg aagacgaacg catttatcta gctaaacaat atgcaaacgg
    68401 tcaacctaaa cgtaacgata gtttcattgt attagatatt agcgctttgg gaactactac
    68461 tacaactaca aaaccaaaca accacaacaa ctacaacaca agcgtaggtg atcagaatga
    68521 agtatattct ttgtcagccg gcaatcaatc ggtttaaatg ggagcttgaa gtttgtttaa
    68581 ctaatctgaa gaaactagga atcaaagata tcgtattgct tttcagcaga cacgatgatc
    68641 agattcctat tttttttgag aaggaatatg gtgttgaagt tcatgtgtac gatgatctgc
    68701 gggacgacaa agagtatatt ccttcgatta aaccatattt atggtggaaa tatttagaag
    68761 aagatcattc gcgtgaggac gaccgatatt tctatatcga ttcggatgtc attttcaata
    68821 aaagaattaa tttgcgcaaa ttgccttcta aagatgatgt ttggtattgt agcgactgct
    68881 gtagttatct aagtcttgat tatattagaa gctgtgaaaa cggagaaaat attctaaaag
    68941 atatggcaaa cattgtaaat gttacagtag aatctttgga aactataaac actaattcag
    69001 gaggcgcaca gtgggttatt aaccgcccta aagcgaatta ttggaaaaag gtttatctgg
    69061 attctaatcg gctatatcgc taccttagag ggcaaaaaac aaatatacaa atctggacag
    69121 ccgagatgtg ggcacagctt tggaacatga tgtatttcaa tattggtcct aaagttcacg
    69181 aggaattaga cttttgtttt gctactgatc caatagaaaa agttaaagaa gtaaaaatct
    69241 tacacaatgc tggagtaaca acaaacgatg aagatttatt tttcaaaggg agatacgtga
    69301 cttctacgcc ttttgatgaa gatttatcat ttgtaaacaa gaaaaaatgc tcttacgcat
    69361 atgttaaagc aattaaggcg gtggttagat gacgcctgaa caagtgactg aagaattgct
    69421 aatagctgtg aaggataata tttacgttac ctggaacgaa gaagatgagt caattaaaaa
    69481 gatgatagct aaaaatgctg tttatcttca aagtaaagtg agtacaacac tttctttttc
    69541 tcctgaaagc ttagaatacg gattgctaat cgaaagatgt agatacgact ggaatcgtgc
    69601 tttagatgag tttgaacaaa atttcgctag tgagttatta ggtttcattc aacattatgc
    69661 gctacaagaa tatattgcag gtgatgtgaa tggcgaataa tcgtagactc gaagaaacat
    69721 tcaacgatgg ttggttaaag attttgacgc aaactaccaa aagaaatgaa ctaggaaaaa
    69781 agattggtgt agaagataca gaaatcactt ctttaaaatt tagaaatctt tccatgagag
    69841 atagtgatat aacagctatg gatgcgatgg gatcgaaatt aactaagaaa gtaaagactc
    69901 catttcatcc aatcgccaag aaatttaata aagatcaata ttttatcgta atcgatagta
    69961 tgcgttacaa cgttatctat gccgattacg ataattttta tatctatttt tatcttgaaa
    70021 gtgtgggtga atatggtgat tgataattct aaagaaaaag aacgtttaaa taagcaaatt
    70081 tctgctatca aaacttcctt agaagagcat tttggcctca aactctttca agactccgta
    70141 ggcgaggatg agctacctga tgattttaat tacttcattc tcgaaacagg agaaatagaa
    70201 atgatcactg agccaaaata tagcgtgggt caaaatctat atctaacttt ctattcagaa
    70261 aatagagaag atttaacagg agattcacta gatattattt cattgattca aaatcgttcg
    70321 attcgttttc agagaatgga tcccaatcat ttaaaactag agaaccaaga tcgctatatc
    70381 gatcaattgg tatttacgtt tagacgatta ttgaagagtg attgtcatgg ctaaaaatag
    70441 ttgggagcta aaaataaatg gacatgatga acttcttgtg cggatggaac gctattcaag
    70501 cgagagcgaa cgactgatta acgaagcatt gaaatcaaaa ggttcggcta ttgcagtgga
    70561 taggattaca gaaaaaattc ctgtttctga agcagattta agaagagggc accaacacgc
    70621 aaaaaatagt cgtccactta agactcaata cattaatttg ggtttcatca ttagacctac
    70681 aagaaaattt gagtatttaa aatatcctga tttggggata ggtacttcta aaagaaatca
    70741 gccggacgaa tttatgagaa gaggattagg tcttgcactt gatccaatta cagaacttct
    70801 gattcgtcaa ttcgataaat taaataaata ggaggaacaa caatggctaa aacaacaaca
    70861 gtaacaactt ttgacaatat aagtattaaa agaatttctt ttaattttaa gaatgcaaca
    70921 aatgcaattt caactgattg taatggacaa ttagatggcg aaacagaaat gcagagaatt
    70981 gtaaaaaaat gcggttcaac agaagtaaaa tcgaaatcta aaccaatcaa tatgacggta
    71041 acaattactg cacatgtacc gatggaagtt tatcgacgct tcaatgggtt gaaacaagat
    71101 gaacgtatta aatcgggaat ttactcttat ggtcctgatt ccgtagggga agatttctct
    71161 cttgctgcag agatcgtgga tgatttcgaa gaaaaaaata agctgattgg tatgttagca
    71221 tgcacttcga atacaggatt aacattctct attgaaaatg gtgcggatga agtagctgcg
    71281 ttagaactag aaacaaaagt tatgcaagat gaatttggta aattttatca tgaagcaatt
    71341 gttgcagaac ttgaagaaga cttaacagat caatggatga cgaatctatc tgctgatgtg
    71401 attaaaaaaa cttcagttgt gacaactacg gccactcaat cacagtaaaa aaaacggagg
    71461 tagcgaaatg atcgaagatt actcaaaaat tgaactaaac gatggaacaa ttttgaattt
    71521 agaacctaaa ctgaatatca agaaattatt gatgatcaat agagatttta acacagacga
    71581 gtttgcaaaa atgactgtgg gaaaaggatc catggatatt tctgttattc aaggtgcaaa
    71641 ggctgtgtat attgcttacc gccaagcgaa catgactgat tatatttcat tcgatgaatt
    71701 tatcgataaa tgggattttg atatggctac tgccagctat atttatcaat tgatgatgtt
    71761 caaacaagca cgcgatgctt atcaaaaaga atttgaaaaa gcaaataagg aaaaaaagct
    71821 tcaaaagtaa aaatgccaaa gctcttagtt gaaacgtggg tcgatgtcta ttcgatgttg
    71881 accgacgttt tttctatgcc ttcagatttg gttttaagcg atatctgttt agatgacatt
    71941 ttgcaaatgg cttacaacaa gagtgcttat gaaggatgga aaaactatgc aataaaccaa
    72001 tcccagaaaa actaaagaaa ggaggtaaaa aatggctaaa aagagaacag aagcagaagt
    72061 aacattcata gctaacgatg acggattgaa atctacgtta aaagaaatca gtgctgaatt
    72121 aactaaaaat agagcagaat taaaactaga acaagctcaa ttacaacaga ctggttctga
    72181 atcagacaag ttaggaagta aattatcttc tttagaaaag cagtatgaat tacaaagtca
    72241 aaaagttgaa gtaactagcc aacgtttagc caatgccaaa aaatattatg gagaaaattc
    72301 caccgaagtt cagaaacttg agagagaact gattaaccaa caaacagcgc aacaacgttt
    72361 gtcaaacgaa attgataaaa cgagtaatgc actagctcaa gcaaaaggcg aaatacagac
    72421 gtacgagtct acaatgcaac agttggatag tgaacaaaaa aatgttcaag ctagtgcttc
    72481 tctgattgaa tccgaataca aaaaatggca agcaactgct ggtcaatcag cttctgaatc
    72541 cgagaaatta gcgaaagccc aagaatatgt ttctcaacaa tctgaaaatg cagagaaaac
    72601 gatagatatc ctgagacgac agttagaagc tacacagtct gagtttggcg ctacatccac
    72661 agaagcaatg cagatggagg cgaagcttaa tgatgctgaa cgtgaatttg aagagttagg
    72721 acaagctgct aaaaatgtag atacaactaa cttggacgat atcggaagca aaatagatat
    72781 gaataatcta atggaagctt ctgacgtttt aagcgacatt ggcgataagc ttacagaatt
    72841 agggaaacaa gcagtggact ctgctaatag tgtaggtagt tcccagagta aaatacaagc
    72901 taattttggt ttgactaaac aagaggctga agaattaacg aatgtagcca gagacattta
    72961 ttataaaggt tttggagaat cgttagatca gtccacagat gcattgattt tggtaaagcg
    73021 taatttaggc gatttaaata atcaagattt acaaaatatc acggaacaag ctatggtcct
    73081 agaaaacacc atgggcgctg atatggatga aacgttacgt ggtgtaaatg gcttaatggt
    73141 caatttcggc ttgagcgctc aagatgcaat ggatttaatg gtttcgggta ctcaaaacgg
    73201 tttagataaa acgcacgaat taggcgacaa tatggcagaa tatagccaat tatggagtca
    73261 aatgggatat tcagctgatg aaacgttcgg aatgcttcaa aatggtttag atgcgggtgc
    73321 ttataacctt gataaagtca atgacttagt taaggaaatg ggaatatcgt taacagatgg
    73381 tcgatttgag caaaacatgg atatgtttag tgaaagtact agaaaagctt ttgaagagtg
    73441 gaaaaatggc ggaggaacac aaaaagacgt tattaattcc atgattcaag attttagcaa
    73501 tatggatggt caatacgacc aattaaataa agcttctaca atttggtctg cacttggcga
    73561 agataacgcg atgaaagttg tccaatcttt gactgatgtt aaccatacat ttgatgatgt
    73621 tagtggatct gcacaaaaaa tgaatgaaga ttctactact ccgttacaag aattaaacgg
    73681 aaaaatagct gaattaaagg attcattagc tcctataggc aacacaatca tagatgcact
    73741 cgaaccagta attgattttc taggaaagat ggctgatgcg tttaataatc ttccacaacc
    73801 agtacaggat tatgccgtag cgattggcgg attgactgct gcatttactt tattaatgcc
    73861 aataatagtt ggcttcatgg ctctaggtgg tcctactaca ttaataatag gagcagttat
    73921 tactgttatt gctggagtta tagcaattat aaaaaactgg ggcgcaatta ctgactggtt
    73981 taagggaata tggagtaaat tcactgattg gttgggtggt acttgggaaa gtataaaaga
    74041 aggtgcctca tcagtttggg atggagttaa agaaacctgg tctggatttg tagattgggt
    74101 tcaagatatt tggcaaggag tttctgattg gtttggagag ctatggagcg gattagttga
    74161 aggagcttcc aacatctggc aaggagtcca agagacttgg caagcattcg ttgattgggt
    74221 ttcaaatatt tggaacggag tcaaagaagt atggtcgatt atttgggcag acattgtagg
    74281 aattgttcaa ataccatgga ccttaataac gtcattgatt caagccggta ttaatattat
    74341 cgtgggtatt tttgatgtag ctggacagtt attaggcgca gcttggcaag ctgtttggac
    74401 acctatttct gatttcctta aaaacacttg ggatactatg acacaatggg taagcatcgc
    74461 ttggaatgga attgtaacta cattccatac tatatttgat ccagtagtgg catggtggaa
    74521 tggtatatgg acagctatta gtactacggc ttcaaatatt tggaattcaa ttagtgcaac
    74581 agcttctagt atttggaaca gtatcaagaa tacaatcact agcttggtac aagcagctgc
    74641 tacagtaatt caaaatattt ggtcaactgt atctagttgg ttaggtggaa tttggaattc
    74701 aatcagctct acagcatcaa atatctggaa tagcgtgact agtagtataa gcaatgctat
    74761 aaacgcagct aaaagtgcca ttcaaagtgt ttggaatagt atatcttcgt ggatcagcgg
    74821 aatttggaac ggtatcaaaa acactgcttt gaatctttgg aatggaatta caagcactat
    74881 tagctctaaa gtaaacgatg gaaaaaatgc aatttcaagc ggttggtcca atctaacagg
    74941 tattgtttcc gacatattca ataatgttaa aagtacaatt gctaacattt gggaaggtat
    75001 caaaaagact gttagcgctc caattgattg gatcagagat aaaatcagta gtatctttga
    75061 taatttgaat atttctatac cacatattcc gttaccacat tttaaattga gcggagaatt
    75121 caatccattg aaggggaaaa tcccaacgtt gtgtgttgat tggtatgcga aaggtagtgt
    75181 gtttaattct ccgaatatta tcggtgtcgg cgaagcagga cctgaagcag ttttaccttt
    75241 gaaaagatct gtgctgcaag aaattggtga tcgtatcttg agtagcacat cagtttcatc
    75301 tagggcacaa acgattcaac ctgtgaataa ctacgaattc aatttcacaa ttgatggtaa
    75361 cgcagatgag gttactatga agcaaacaac tcaacaaatc attgatagca ttacaaaagt
    75421 tcaaaatgat aatgcttcgg catggcgtta aacaggagag tatttctcct gtttttttag
    75481 tattaaaaag gatgtgaaaa aatgactgat tgtatacatt ctataatcga tggatttcct
    75541 gattatttgc ataaattggc tttagctgaa agaccaacca taccttctcc aaaaagacag
    75601 agagttgaaa cttctgtttt aggaaggtta ggtggcttag tacaagatta ctcgtttgaa
    75661 gacatgtcgt ttacattgca ctataactat ttagaggatg tggaagacca tcaagcgttc
    75721 aagcaatcgt tttatatcat gcgtcattgg ttaaattatg caaagaaatt agaattctct
    75781 gatgatccca acgtctatta tgttatccag actatcgata ttggggatgc agaaaacgat
    75841 attgttgaat ggggagagtt cgatgtaaat attactgcga aaccattcgc aagagttcaa
    75901 gaagatgtac ctataaccgt agataaacca cagtcattta acttgctgaa taatagttta
    75961 gaagaaagtt ttccaaagat tatcatcact ccttcagcta cttcatgcca gttcatctta
    76021 aatgattatg tgtttagttt tgaaggctta gtagtaggaa ctgacgtagt cattgatagt
    76081 gatttgatgc tttgctacga agagcaatcg gacggagata ttttagatcg gtccaacaaa
    76141 atgaagacca tgcaatatcc gacattgcaa gtggatatta attattttaa ttgtactggt
    76201 ttgagcaaaa tacaaattta tcgtaatggg ttaaggtagg tgaaatagat gatcgataat
    76261 ttaataacta tttacgataa aaacgacgcg aataatttag ctgaacattt atatgatacg
    76321 caaggtttag gcgctttgtc agactggtta acagctactg ttagcaataa attaaacgga
    76381 gccgagatat ttcagggtac ttatccaata agcggaacta atgcagattt gattgtagaa
    76441 ggacgtatta ttcagtgtta tgtagatgaa aatcgagcaa aacagcgtct acggatttat
    76501 tatgcaaaga cttctgtaat aggcaatacg atagaagtaa aagctgaacc tattttcaat
    76561 gatataagaa aatcggtgtt gaataaatat gacagtggaa cagaaaagat cactgctagt
    76621 caggcatggc aaaacgcaaa aactttagcg aaaccagtta ttccttcaca gttttctttc
    76681 tcgtcattag tagatacgct tgctaatgtg aagatagaaa aggcgaattt tttagaattc
    76741 tttggtggaa aagagggatc tattctagat cgatttcatg gggaatttct aaaagataat
    76801 aacacattac gtcatgaaaa aaggctaggc acggatcata aaatcaaagc gatttatact
    76861 aaaaacttaa ctggtcttga cttagagatt gatgctcaaa gtgttttagt tggagtttat
    76921 ccattcatta gcagctcttc agaaggagaa gacgagatca ctctaccaga agaagttatt
    76981 ttcacggatt acgtggatga ttatcctgct ggatatgttt cttttgttga ttttaaagac
    77041 aaagcgactg atgtagccac attaagggaa gctgctaaag actggttgaa aacaaacata
    77101 gataaacaaa aaccacaagt gagtggttcg attgaattag taccattgag gcatcaaaga
    77161 ggctatgaaa aatttgttga tctagaaaaa gtttcgatgg gtgacggagt agatgtgtat
    77221 catccacagt taaaagtgaa tatgtcagcg agaattgtgg aatatacgtt taatgttcta
    77281 accaattcat acgataaatt agttgtagga aacgtcaaaa caaacttctt agaaaacaca
    77341 gagaataatg tcagcaattt gattaatgat gccattgatc aattgaaaaa cggtggcgaa
    77401 atcagtgatt tactcaatga tattgtagat catcaaactg atatgattac tggtcaaaat
    77461 ggtggttatg ttttattaga tcctaaagaa gcgcctagtc gtattttgat tatggacaca
    77521 ccagataaga ataccgcaag gaatgtttta caaatcaaca atgctggtat tggtttttct
    77581 aaaactggca ttaatggaac atatgaaacg gcatggacgt tagatggcgg attcaatgcc
    77641 tcgtttatta cggctggtga aatagtagga attactatta gaggtactac attaattagt
    77701 gatggtgctg attatagaac aagtattgct aatggcaaaa tgacttggta ctcaaaaaaa
    77761 gttaacaaag atattatgga gctagaagca cgtgattatg taagtgctga tgccggtatt
    77821 gtatcataca ccatgaaaac tggtggtggt ttcatgatta gaaatccaca gggtaacttg
    77881 gtttttagta cgtgggataa tggtaataac agaccgtttc tatcttttgg tgcgcccaat
    77941 ttcaggtata gcaatgctag ttatgtaact tctggcgacg gtagttcttt aagcattaat
    78001 ggtagtgcgg gtaactcatg ggaatttaag gtagctggta ggactatgaa atttactagt
    78061 gatggtatgc taacgttacc aggttgtttt tttggttcat gggaagatgg gaaacttgct
    78121 aggtttgaac aatcaacggt acaagtatat aaagatttta ctgttagagg tactaaaaac
    78181 tcaactgtac caacagaaca ttatggacaa cgactattga acgcttatga aactccagaa
    78241 tattatttcg ctgattatgg ggaagccgtt acaggtgacg atggtaaagt tcgtgttgat
    78301 attgacccca tgtttgctga aacagtaaat ctaagtcggt atatgacaca tgtgacacct
    78361 acagaactag ttttgtgtgc tgttactcat gaagatattg accatttcat cattgaaact
    78421 agtaagccaa acgtattagt tagatggaat ttagtggcac accgtctagg gtatgaagat
    78481 attagattaa aagaggatac agcatatgat agcacagtgc ttgaccaaaa acgtttttaa
    78541 aacgaagaca aggaggtata taaatggcta gcagtttata taatttggct ttagatttca
    78601 gcaaagaatt aaactacacc aaagctatta tggctcgtca aggtgataaa gggattacgg
    78661 tgacggttaa accgtttcta aatggcttgc agatggatac gagtggcgga acatttactt
    78721 taaaaggaac aacaccatct aaccgttacg tagataatgt tgcaactagt gtaactagtg
    78781 aagaagtcac gttttctctt gatggcacat ttatgagtga agcaggatat tataaacact
    78841 gctacgtaga atatagaaaa gacaatcaaa ttttaacaac gcaagatatc atttttttct
    78901 cactaggagt gtctgacatt tcgcaaggcc aagccgatga atatgtttcg caattagaag
    78961 agttgattcg aaagtacaac gaaacttttg atgcttttat ggctgaaatc aaaggtagag
    79021 tggatagctt aaatcaacag attactgatt taactggtca agctaaaacg ctacaagaca
    79081 agttagatgc tctgaaagaa gaaatttcta agttaggtaa cttacaagtg atgtacagta
    79141 acagcatcga cttcggggga tatgattata gcggtaagcc gaatttaatg tccaaactaa
    79201 aatcgagcga ttttaacgtt ggttaccacg ggtcactaac tttggataac gaaaagttac
    79261 attttacttc tgatggtaca ggaagcatta ttatgtttac gcgtattaat acacctcagc
    79321 ttactagtgg gaaaacctat actctgagtg cgaaagttcg atttgatgaa ggaactacag
    79381 gagctattga taaattacgt ttggtgtatc gtacatcacc aggagaaaag atattattgg
    79441 aagcaaatag tacaaatatt acaacagatg atgtagggaa agaaataaca atcaaaggta
    79501 cagctaacgt taattatcaa atcacaaatt tagatcgatt ttatatgagt attagctttg
    79561 ttgacaggga taaaataaat ggcggattta agttgtacga catcaaaatc gaagaaggct
    79621 caacagccac accgtaccag cctaatctac ttgatgcacc gtattatttg agtaaggtgg
    79681 ctttgggtga gaatctaatt aaaccagaat cacaacaacc agttactaat agtaactatc
    79741 ttattaacac ctataacatt aaaccaatgg taaaaggtaa gaagtatacc atcacacttg
    79801 aaggaactaa gccagcaaca caggttttta gaccattttt cacacgagca acaggagatg
    79861 catgggaggt tggtgactta caaccagtag aaggcttaac taatgtgtgg tctaaaacat
    79921 ttacagcagc agatgactca caccctacta ccccacaagt gcagatttat caagtaccaa
    79981 gcacaagtgt aggacaatgt acaattaagt ggttaaaact agaggaaggc aatactcgaa
    80041 ccccgaatat tagtgagtat aaatatcgtg gtactggtat gcgtgattca aacaatccaa
    80101 aagattatgt ttgggatcta gcaccagaat atgtcgaaga taatttggcc acagatatta
    80161 aaatttctga aattactggt aaagcaaaca attataccga tgggaaagta tcggagatta
    80221 attcgcagtt gactgcttca attaatgaag tagacaccac agctaaggat gctcaaacaa
    80281 aagcgaatgc taatgcgact gctatagatg aattagacaa taagatcgat gaacgcatta
    80341 atgatacagc tactaccaca ttaacagtta caaacgggaa taccggatca gcaaagcttt
    80401 atcgtgaagg aaaaacagtt tctatatatt ttgtggcttt aaacggaaaa cgcagtggtg
    80461 gaaatgattc aacgatacta acaattccag aaggctatcg gccaccaatt agttttgagc
    80521 aactggttgg ctcgatagac cgttctactt tgaacagtgc tcagttatct attggtgcag
    80581 atggagccat taaatggcga agaaactcaa gttatggatc ggattatacc tttgcaatta
    80641 cttacacgat ttagaaaagc gtgaatcgat atgaaggcag catatagacc aattgaacct
    80701 tacggattcg agcaaatcat tgtgaatgat gaagaacatt taccggaaga atgcacagaa
    80761 gtcgaaccac cgattccaaa ttggaaaccg aaattcaatt actgggaggg aaataaatga
    80821 aaaacatttg gaaatatgga cgtactggcg gagagtacgc aggaaaagta ttggacgaca
    80881 tgcttgtatc cgttccttac acagatcagc caccgcttga aggaattcgt gctgatggcg
    80941 aaccgttaac aatcgctgat caaatgtttg atcctaaatt gaatcaatgg attattttag
    81001 cgaacgcact agatcacaac gatttaaaca atctcaaagc aatgtatgag tcgttagaaa
    81061 atgagaacgg cgatttaaaa cagatcaatg ccaaactcat gctaagcgat gtagcaatta
    81121 aacaggaaaa tactgcattg aaagaaaaag cggatagttt agcacaaatc aattcaaaaa
    81181 tgatgcttgc ttcgttacaa aatagcaaag acatttcaga aattaaagag caactaaatc
    81241 cagcttcaaa gggaggtgag tagtatgttt agttttagcg atgtgaaaat gatgtatgat
    81301 tggggctgtt tcactaacga acaagtaatg gttttcgttc cgttgtgcat tactgaagaa
    81361 aaagcagata aaatcattag caaagaagag agcgcatctt aattgatgtg ctttttattt
    81421 tgattcaagg agttgtcaca tgattaattt aggggaatgg ggagcgatag caggatcaat
    81481 aaccgctatc gtttctttga ttttattagt aataaaacca attactgcat ctttctcgaa
    81541 gattactgag actctttcaa aagtaagtca caatttagat ttgctgacta aagatttaga
    81601 atcgagcaaa tcagatcgat tgatgattca tgaagaacta aagaaacacg atgaaagatt
    81661 agatacacat gcagaaaaat tggtagaaca cacgcaacaa attaaaactt tatttaggga
    81721 gagaagaaaa tgaataataa aacgttcgaa gtactaaaat ggttcgcact ggtaattatt
    81781 cccgcactag ctactttcgt ggggttagtt ggtaaagcgc tcaattggca gtacacagat
    81841 atctgtgttg tcatcattac tggttttggc gcgtttttag ggagtgtgtt gggtgtatca
    81901 aatcgaacct acaaaatgtt ctcggctgaa agcgaagaag gaggaaacaa atgaaaaaga
    81961 aaattactat tactgcgatg agcctgttaa cggctctttt tttattaccc attaatacgt
    82021 ttgcttatac tattaatgac gagtataatt tagcgccgaa tcaaggagac tccagattag
    82081 caattcctaa caaaattatt ttgcacgaaa ctggaataga tgcaccagca agaaacgtag
    82141 ccgccaacat gaaaaataat tataacggaa gcaattctta tactacagat gttattggtg
    82201 acggtgggat tgtttaccgt gtgggtgagc aaggatatgt ttcgtgggga gctggtaacg
    82261 ctaatcctta tgcgcctgta cagattgaat tacagcgcac atatgataaa gcattgtttg
    82321 aaaaaaacta tcgagcttat attgaatata caagagatag tgcaaaaaaa tatggaattc
    82381 cattgactct tgatcaagga acttctttat ttacaaaagg aatcatttct catttgtggg
    82441 tgacaaatta tgtttggggg aaccacacag atccatatgg ttacttatcg caaatgggag
    82501 ttagcaaaga aaagcttgct tatgatttag ctcatggatt taccgatgaa aatccaacaa
    82561 cttctgaaaa caagcctgtc attgatccaa cacgagctgg tgcagctaat cctacgctga
    82621 cagatggaac aaatcacgcc cacattgatc agtttgggga aatcgaaaac gcaaacttgc
    82681 atgtggctgg atggcacatt gctaactata aatacgagta tattttcatt atggactaca
    82741 atactgggaa agaattagct cgagtaagag ctgatggaat ttatagacca gatgtaaa
//
LOCUS       DAFEEZ010000005        82072 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000005
VERSION     DAFEEZ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 82072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82072
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.005"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..227)
                     /locus_tag="LP245_000388"
     CDS             complement(<1..227)
                     /locus_tag="LP245_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518331.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVP"
     gene            complement(323..1117)
                     /locus_tag="LP245_000389"
     CDS             complement(323..1117)
                     /locus_tag="LP245_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HBL1518332.1"
                     /translation="MSKQCAKCGGKIGLTSYKIKDKQIVCGNCMKKAGYGMTTPYKII
                     RSLNLEDLDKDPSEKRKLNISDHTAQNNHDIGNDRMRTTEEMVEFCLKYGYGKGMTKK
                     WTTHHFNLISDQLNSDEYVIFCFVGLHNYISSTKHDNNYAYALTNKRLIVAQQKMIGN
                     NVQSIILDNLNNISKKRGVLLGTLTIDTLGKVLNVAVDKDTVDRISDSLNEIIYNLKR
                     RNISATNSNTSTISSASEIRKYKELLDDGIITEEEFNKKKQELLDL"
     gene            1763..4570
                     /locus_tag="LP245_000390"
     CDS             1763..4570
                     /locus_tag="LP245_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL1518333.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            4761..5252
                     /locus_tag="LP245_000391"
     CDS             4761..5252
                     /locus_tag="LP245_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1518334.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            5355..6344
                     /gene="manX"
                     /locus_tag="LP245_000392"
     CDS             5355..6344
                     /gene="manX"
                     /locus_tag="LP245_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBL1518335.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            6377..7180
                     /locus_tag="LP245_000393"
     CDS             6377..7180
                     /locus_tag="LP245_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBL1518336.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            7201..8115
                     /locus_tag="LP245_000394"
     CDS             7201..8115
                     /locus_tag="LP245_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBL1518337.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            8198..8572
                     /locus_tag="LP245_000395"
     CDS             8198..8572
                     /locus_tag="LP245_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBL1518338.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            8711..8956
                     /locus_tag="LP245_000396"
     CDS             8711..8956
                     /locus_tag="LP245_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL1518339.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            9128..10192
                     /locus_tag="LP245_000397"
     CDS             9128..10192
                     /locus_tag="LP245_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBL1518340.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            10438..10863
                     /locus_tag="LP245_000398"
     CDS             10438..10863
                     /locus_tag="LP245_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL1518341.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            10856..11305
                     /gene="nusB"
                     /locus_tag="LP245_000399"
     CDS             10856..11305
                     /gene="nusB"
                     /locus_tag="LP245_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBL1518342.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            11402..12256
                     /locus_tag="LP245_000400"
     CDS             11402..12256
                     /locus_tag="LP245_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBL1518343.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            12257..13594
                     /locus_tag="LP245_000401"
     CDS             12257..13594
                     /locus_tag="LP245_000401"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBL1518344.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADHYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            13599..13823
                     /locus_tag="LP245_000402"
     CDS             13599..13823
                     /locus_tag="LP245_000402"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBL1518345.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            13825..14715
                     /locus_tag="LP245_000403"
     CDS             13825..14715
                     /locus_tag="LP245_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBL1518346.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            14724..15542
                     /locus_tag="LP245_000404"
     CDS             14724..15542
                     /locus_tag="LP245_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBL1518347.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            15649..16098
                     /locus_tag="LP245_000405"
     CDS             15649..16098
                     /locus_tag="LP245_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBL1518348.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            16116..17798
                     /gene="recN"
                     /locus_tag="LP245_000406"
     CDS             16116..17798
                     /gene="recN"
                     /locus_tag="LP245_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBL1518349.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(17853..17969)
                     /locus_tag="LP245_000407"
     CDS             complement(17853..17969)
                     /locus_tag="LP245_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBL1518350.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(18042..18998)
                     /locus_tag="LP245_000408"
     CDS             complement(18042..18998)
                     /locus_tag="LP245_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL1518351.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            19169..19537
                     /locus_tag="LP245_000409"
     CDS             19169..19537
                     /locus_tag="LP245_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBL1518352.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            19707..20138
                     /gene="mraZ"
                     /locus_tag="LP245_000410"
     CDS             19707..20138
                     /gene="mraZ"
                     /locus_tag="LP245_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBL1518353.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            20159..21118
                     /gene="rsmH"
                     /locus_tag="LP245_000411"
     CDS             20159..21118
                     /gene="rsmH"
                     /locus_tag="LP245_000411"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBL1518354.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            21123..21524
                     /gene="ftsL"
                     /locus_tag="LP245_000412"
     CDS             21123..21524
                     /gene="ftsL"
                     /locus_tag="LP245_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBL1518355.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            21525..23717
                     /locus_tag="LP245_000413"
     CDS             21525..23717
                     /locus_tag="LP245_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBL1518356.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            23743..24705
                     /locus_tag="LP245_000414"
     CDS             23743..24705
                     /locus_tag="LP245_000414"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBL1518357.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            24719..26080
                     /locus_tag="LP245_000415"
     CDS             24719..26080
                     /locus_tag="LP245_000415"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBL1518358.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            26106..27194
                     /gene="murG"
                     /locus_tag="LP245_000416"
     CDS             26106..27194
                     /gene="murG"
                     /locus_tag="LP245_000416"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBL1518359.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            27209..28429
                     /locus_tag="LP245_000417"
     CDS             27209..28429
                     /locus_tag="LP245_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBL1518360.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            28585..29910
                     /gene="ftsA"
                     /locus_tag="LP245_000418"
     CDS             28585..29910
                     /gene="ftsA"
                     /locus_tag="LP245_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBL1518361.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            29933..31174
                     /gene="ftsZ"
                     /locus_tag="LP245_000419"
     CDS             29933..31174
                     /gene="ftsZ"
                     /locus_tag="LP245_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBL1518362.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            31191..31868
                     /locus_tag="LP245_000420"
     CDS             31191..31868
                     /locus_tag="LP245_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBL1518363.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            31882..32481
                     /locus_tag="LP245_000421"
     CDS             31882..32481
                     /locus_tag="LP245_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBL1518364.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            32496..32783
                     /locus_tag="LP245_000422"
     CDS             32496..32783
                     /locus_tag="LP245_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBL1518365.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            32832..33614
                     /locus_tag="LP245_000423"
     CDS             32832..33614
                     /locus_tag="LP245_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBL1518366.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            33635..34342
                     /locus_tag="LP245_000424"
     CDS             33635..34342
                     /locus_tag="LP245_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBL1518367.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            34604..37402
                     /gene="ileS"
                     /locus_tag="LP245_000425"
     CDS             34604..37402
                     /gene="ileS"
                     /locus_tag="LP245_000425"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBL1518368.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(37451..38977)
                     /locus_tag="LP245_000426"
     CDS             complement(37451..38977)
                     /locus_tag="LP245_000426"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBL1518369.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(38992..39639)
                     /locus_tag="LP245_000427"
     CDS             complement(38992..39639)
                     /locus_tag="LP245_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBL1518370.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(39823..40152)
                     /locus_tag="LP245_000428"
     CDS             complement(39823..40152)
                     /locus_tag="LP245_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBL1518371.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            40329..41057
                     /gene="sfsA"
                     /locus_tag="LP245_000429"
     CDS             40329..41057
                     /gene="sfsA"
                     /locus_tag="LP245_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBL1518372.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            41073..42086
                     /locus_tag="LP245_000430"
     CDS             41073..42086
                     /locus_tag="LP245_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1518373.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            42086..43363
                     /locus_tag="LP245_000431"
     CDS             42086..43363
                     /locus_tag="LP245_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL1518374.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            43426..46128
                     /locus_tag="LP245_000432"
     CDS             43426..46128
                     /locus_tag="LP245_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL1518375.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            46280..46597
                     /locus_tag="LP245_000433"
     CDS             46280..46597
                     /locus_tag="LP245_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1518376.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            46627..46947
                     /locus_tag="LP245_000434"
     CDS             46627..46947
                     /locus_tag="LP245_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL1518377.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            47055..48515
                     /locus_tag="LP245_000435"
     CDS             47055..48515
                     /locus_tag="LP245_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1518378.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            48583..48804
                     /locus_tag="LP245_000436"
     CDS             48583..48804
                     /locus_tag="LP245_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518379.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            48835..49017
                     /locus_tag="LP245_000437"
     CDS             48835..49017
                     /locus_tag="LP245_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBL1518380.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKERNN"
     gene            49017..49430
                     /locus_tag="LP245_000438"
     CDS             49017..49430
                     /locus_tag="LP245_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBL1518381.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            49553..50734
                     /locus_tag="LP245_000439"
     CDS             49553..50734
                     /locus_tag="LP245_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1518382.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(50805..50969)
                     /locus_tag="LP245_000440"
     CDS             complement(50805..50969)
                     /locus_tag="LP245_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518383.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            51123..51196
                     /locus_tag="LP245_000441"
     tRNA            51123..51196
                     /locus_tag="LP245_000441"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:51157..51159,aa:Arg,seq:cct)
     gene            complement(51265..52404)
                     /locus_tag="LP245_000442"
     CDS             complement(51265..52404)
                     /locus_tag="LP245_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1518384.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(52703..53338)
                     /locus_tag="LP245_000443"
     CDS             complement(52703..53338)
                     /locus_tag="LP245_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518385.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINSASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(53451..54086)
                     /locus_tag="LP245_000444"
     CDS             complement(53451..54086)
                     /locus_tag="LP245_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBL1518386.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(54120..54581)
                     /locus_tag="LP245_000445"
     CDS             complement(54120..54581)
                     /locus_tag="LP245_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBL1518387.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNLSAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(54711..55142)
                     /locus_tag="LP245_000446"
     CDS             complement(54711..55142)
                     /locus_tag="LP245_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL1518388.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(55160..55480)
                     /locus_tag="LP245_000447"
     CDS             complement(55160..55480)
                     /locus_tag="LP245_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1518389.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            55779..56555
                     /locus_tag="LP245_000448"
     CDS             55779..56555
                     /locus_tag="LP245_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBL1518390.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            56570..56773
                     /locus_tag="LP245_000449"
     CDS             56570..56773
                     /locus_tag="LP245_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1518391.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            56789..57127
                     /locus_tag="LP245_000450"
     CDS             56789..57127
                     /locus_tag="LP245_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBL1518392.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            57114..57293
                     /locus_tag="LP245_000451"
     CDS             57114..57293
                     /locus_tag="LP245_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518393.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(57336..57806)
                     /locus_tag="LP245_000452"
     CDS             complement(57336..57806)
                     /locus_tag="LP245_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518394.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            57893..58591
                     /locus_tag="LP245_000453"
     CDS             57893..58591
                     /locus_tag="LP245_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBL1518395.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            58769..59110
                     /locus_tag="LP245_000454"
     CDS             58769..59110
                     /locus_tag="LP245_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518396.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            59103..59774
                     /locus_tag="LP245_000455"
     CDS             59103..59774
                     /locus_tag="LP245_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBL1518397.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            59780..60466
                     /locus_tag="LP245_000456"
     CDS             59780..60466
                     /locus_tag="LP245_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518398.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            60469..61218
                     /locus_tag="LP245_000457"
     CDS             60469..61218
                     /locus_tag="LP245_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1518399.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            61230..61499
                     /locus_tag="LP245_000458"
     CDS             61230..61499
                     /locus_tag="LP245_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518400.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            61505..61669
                     /locus_tag="LP245_000459"
     CDS             61505..61669
                     /locus_tag="LP245_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518401.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            61662..61961
                     /locus_tag="LP245_000460"
     CDS             61662..61961
                     /locus_tag="LP245_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518402.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            61961..62263
                     /locus_tag="LP245_000461"
     CDS             61961..62263
                     /locus_tag="LP245_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBL1518403.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            62303..62668
                     /locus_tag="LP245_000462"
     CDS             62303..62668
                     /locus_tag="LP245_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518404.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            63158..63298
                     /locus_tag="LP245_000463"
     CDS             63158..63298
                     /locus_tag="LP245_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518405.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            63295..63483
                     /locus_tag="LP245_000464"
     CDS             63295..63483
                     /locus_tag="LP245_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518406.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKNLI"
     gene            63491..63685
                     /locus_tag="LP245_000465"
     CDS             63491..63685
                     /locus_tag="LP245_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518407.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(63718..63930)
                     /locus_tag="LP245_000466"
     CDS             complement(63718..63930)
                     /locus_tag="LP245_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518408.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            64055..64258
                     /locus_tag="LP245_000467"
     CDS             64055..64258
                     /locus_tag="LP245_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518409.1"
                     /translation="MVKVREQFKIVSDEDNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            64255..64527
                     /locus_tag="LP245_000468"
     CDS             64255..64527
                     /locus_tag="LP245_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBL1518410.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            64528..64713
                     /locus_tag="LP245_000469"
     CDS             64528..64713
                     /locus_tag="LP245_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518411.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            64700..65047
                     /locus_tag="LP245_000470"
     CDS             64700..65047
                     /locus_tag="LP245_000470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518412.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            65007..65483
                     /locus_tag="LP245_000471"
     CDS             65007..65483
                     /locus_tag="LP245_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HBL1518413.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(65629..66357)
                     /locus_tag="LP245_000472"
     CDS             complement(65629..66357)
                     /locus_tag="LP245_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HBL1518414.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            66405..66683
                     /locus_tag="LP245_000473"
     CDS             66405..66683
                     /locus_tag="LP245_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518415.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            66685..67071
                     /locus_tag="LP245_000474"
     CDS             66685..67071
                     /locus_tag="LP245_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518416.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            67068..67448
                     /locus_tag="LP245_000475"
     CDS             67068..67448
                     /locus_tag="LP245_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL1518417.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            67560..68012
                     /locus_tag="LP245_000476"
     CDS             67560..68012
                     /locus_tag="LP245_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBL1518418.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            68009..69736
                     /locus_tag="LP245_000477"
     CDS             68009..69736
                     /locus_tag="LP245_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBL1518419.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            69800..70987
                     /locus_tag="LP245_000478"
     CDS             69800..70987
                     /locus_tag="LP245_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL1518420.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            70959..71528
                     /locus_tag="LP245_000479"
     CDS             70959..71528
                     /locus_tag="LP245_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HBL1518421.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            71541..72905
                     /locus_tag="LP245_000480"
     CDS             71541..72905
                     /locus_tag="LP245_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL1518422.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            72907..73188
                     /locus_tag="LP245_000481"
     CDS             72907..73188
                     /locus_tag="LP245_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBL1518423.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETDQ"
     gene            73166..73492
                     /locus_tag="LP245_000482"
     CDS             73166..73492
                     /locus_tag="LP245_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBL1518424.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            73482..73820
                     /locus_tag="LP245_000483"
     CDS             73482..73820
                     /locus_tag="LP245_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518425.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            73810..74175
                     /locus_tag="LP245_000484"
     CDS             73810..74175
                     /locus_tag="LP245_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBL1518426.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            74182..74808
                     /locus_tag="LP245_000485"
     CDS             74182..74808
                     /locus_tag="LP245_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1518427.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            74808..75272
                     /locus_tag="LP245_000486"
     CDS             74808..75272
                     /locus_tag="LP245_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518428.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            75467..77776
                     /locus_tag="LP245_000487"
     CDS             75467..77776
                     /locus_tag="LP245_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBL1518429.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            77788..78492
                     /locus_tag="LP245_000488"
     CDS             77788..78492
                     /locus_tag="LP245_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1518430.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            78489..81248
                     /locus_tag="LP245_000489"
     CDS             78489..81248
                     /locus_tag="LP245_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1518431.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYER
                     PAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSG
                     YLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINW
                     ARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISSI
                     VIPPK"
     gene            81261..>82072
                     /locus_tag="LP245_000490"
     CDS             81261..>82072
                     /locus_tag="LP245_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBL1518432.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETRIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIET"
BASE COUNT        27793 a        13459 c        17146 g        23674 t
ORIGIN      
        1 ggcacgtcag tcacgatatc aaacaaaaag tatacaccct tcttcattct agttttcgca
       61 gcaggaattt tgaaatagtt cttattagaa tagtagagat tgattaataa gctatcttcg
      121 attgctaaaa agaaaacttc tgaatcccac accttataaa aatctttgac aaatctattc
      181 gaaggatcga atttaaacca taattgtgtt tttccttcca ttaacatata aagttcacct
      241 caaaaagagt atacgaacaa atgtttgtat tgtaaataga aaaagatgag ctaaattaaa
      301 tgcccatctt ctttgataga tattataaat ctaataattc ttgtttcttt ttattaaatt
      361 cttcttctgt aatgattcca tcatccaata gttctttata ttttcttatt tctgaagctg
      421 aggaaattgt tgatgtattg gaatttgtag cagaaatatt tcttcttttt aaattataaa
      481 taatttcgtt taaagaatca cttatcctat caacagtatc tttatcaact gcaacattca
      541 atactttacc aagagtatca atagttaatg tacccaacag cactcctctt tttttactaa
      601 tattatttaa attgtctaat ataatacttt gtacattatt gcctatcatt ttttgttgag
      661 ctacaattaa acgtttatta gttaatgcgt atgcataatt attgtcatgc ttagttgatg
      721 agatataatt atgcaatcct acaaagcaga agattacgta ttcgtcactg ttaagttgat
      781 ctgatattaa gttaaaatga tgagttgtcc attttttagt cattccttta ccgtagccgt
      841 atttaagaca aaattctacc atctcttcag tggttctcat tctatcatta cctatatcat
      901 gattgttttg tgcagtatga tcagatatgt ttaattttct tttttctgat ggatccttat
      961 ctaaatcttc taaattcaaa gatcttatta ttttataagg agtagtcata ccgtaaccag
     1021 cttttttcat acaattgccg caaacaattt gtttatcttt gattttatat gaagttaagc
     1081 caattttacc tccgcacttt gcacattgtt tactcacatt agttcctcct agatatcagc
     1141 tttctactac tattaacatt ctatcaatag tgaccatact ttgaccatac tttttagaaa
     1201 gaatagaaaa ttccaagata tttaataata gaagaaaagc actaacatca tgggttcaga
     1261 agaattgaga gcttatcagg aaacagtata attgaagtgt ctgtttatcc agtagctcaa
     1321 gaagcttaat tgaatcttat gattaaagag gttgtgacaa gacttttgtc acagcctttt
     1381 ttgtttataa aaataaaagt tgtagtggag gctacgaagt ttactttgtc tttttacact
     1441 taatattttt ttgccaattt ggaatcagga tgttttgata actatcgttt tcaattgatg
     1501 gaagctatat tgtttgctat cagtgaaata attatatggt aaacagtgtt ctttttcttg
     1561 tttccattat aaaaatcgta tcgggatttt tcgttctttt aaattgaaca tttctatcta
     1621 tccgcgtgtt atcaacaaaa caaaatcagg taaatagttg acgaaacaga aataaataca
     1681 tagtattatg ttttgaagcc taagtacaat agtctataga aaaggagcga taccattggc
     1741 aaaacgcatt gaccgaattt atatgtatgt caaagaaaaa accgctcatt taacaaaggc
     1801 agaatatgat caaggagtaa caacacagga aattgctgaa gtgttaggga ttcagcgaac
     1861 aaatagcagt aaagatctga atcagctagt gcgcgaagga aaactgataa agacagacgg
     1921 acgaccagta cgttacatat atcaaacact cgttacgcac gtaaagccag ttacaaaaca
     1981 tgtagtcagt tacaaagaaa cgccggtctc tgaagaaaaa aatacactcc aaatagatac
     2041 taaggatatc tttgcaaaaa tcattggagc taacggcagc atgaaaaatt cagtggaaca
     2101 ggcaaaagct gcgattttgt atccgccaag aggattaaat tgtttgatta caggacctac
     2161 cggatcagga aagacttatt ttgcacacgc gatgtatcat tttgcaaaag cgcatcatgt
     2221 aatagatgag gaaacggaac tgattgtttt caattgtgct gattatgcca ataaccctga
     2281 gcttttgatg agtcatttat ttgggtacgc aaaaggtgct tttacaggcg cagatgaaga
     2341 aaaaatgggg attatcgatc aagcggatgg cggtatgctg tttttggatg agattcaccg
     2401 gttgccgcct gaaggtcaag aaatgatctt ttactttatg gatcatggaa cttacagtcg
     2461 tcttggggaa acaacgaaat cccatgaagc aaatgtacgg atcgtaggtg cgaccacaga
     2521 agacccaggt tcttctctat tagaaacttt tgttcggcgt atcccaatca atatcaaact
     2581 tccggctttt gaaaaacgtc ctgcaaatga gaaagtcgat ttagtaaaaa tcatgattgc
     2641 ccacgaagca aaccgcacgc agcgaaagat ttctttgaca gaagatgtag caaaagcatt
     2701 gatcggcagt gtgacctatg gaaatatagg acaattgaag tcaaatatcc agttagtatg
     2761 tgcacgagga tttctaaatc atatgcaatc acccgaaatc tcgatcacaa tcgatgattt
     2821 gacagaaggg attcgtagcg gattgattca attagcaagc aaccgcagtg caatggcaga
     2881 gctttctaaa atattggagc caaagataac tgtagcacca aatgatacga tcatgaaaat
     2941 ccaatcggac tcctatgagt taccttataa tctatatgat atcatcggag ataaagcagc
     3001 tttactgaag tcggatggtt tggatcaaga agcaatcaat catttcattt ctacagatat
     3061 caacatccat ctgaagtctt tctataaaga ccatggtttt tcttttaatg cagacagcaa
     3121 attagcagaa tttgtagatc cgaaaatcat agaagtgacc aatcagattt atgtaatggt
     3181 caaaagatct ttaccatatg agtttcagca aaactttatt tatgctatga gcttgcatat
     3241 cagttctttt ttgaaaaaaa tcaacttagg agaagaacgg catacgaatg ataacatccg
     3301 tgagatggct tttgattttc cagatgaata tgctgttgcg aaagaagtgc gtagttatat
     3361 cgaaacgtat tttcaagtgg agattccaga aagtgaagac tattacttga ccgttctact
     3421 cgtctcgtta cgggcaaatc aagcaagcgg cagaatcggt gtagtcgttg cagctcacgg
     3481 aaacagcaca gcaagcagta tggtccaagt tgtccaacag ttgttagatg cagagaacgt
     3541 acgagcagta gacatgcctt tggatatgga tccgaaaaca gcattggacc gaattgaacg
     3601 caatgtacaa gaagtagatg aaggaagcgg ggtcatactc ttagtagata tggggtccct
     3661 tgcgtcgttt aattcgcaaa ttcaaagaga cactggaatt ccagtacgta ctgttgatat
     3721 ggtaacaact tctctagttt tggaaactgt acgaaaggtc tcagtattag ggacagatct
     3781 agatatgttg catgaatcat tgaaaaattt tcgaggttac gcagaaatat cttctgtaga
     3841 atctgttcag gaagcaaaac ctattcataa gaaaaaagct gttttggcta tctgcgcatc
     3901 tggcgaaggt acagcacaaa gaatcaaaga attgatcgaa cgagcggtaa acaagcgtca
     3961 agaaacagaa ttagaagttc tagctttgtc gattgtggaa gtgaaagaag aactgccagt
     4021 tatccaaaaa gaatatcaga tcatagctac tactgggatt actgatttga atatccaagc
     4081 cccatttatt cctttagaac gttttattga tcaaaatatc gaagtcattt tggatcagtt
     4141 gctgatggaa tcagaattgg aggaaactga attcatctcc ctagatgaag agtcagctaa
     4201 aaatacgtgt gttgagttta tctctgataa cttcatcttt attaatggta gtaagttaat
     4261 cgatccaatg tggcaatttt ctacacaaat ctctcagacg acgggaatcg gcgatgaaga
     4321 atatggattc aaaatcaacc tagtgatgca cacagcagga atgatcgaac gtattattcg
     4381 gaatgaacca ttgactgtgg aagaaaacga attgacaaat acaacgaatg atcctcttta
     4441 tagccaattg gcagcctcag ttgttctgtt ggaagatcag ataaaagtaa aagtgccgat
     4501 agaagaaatg tattatctgc tacgtctagt ccataatcag ttagataaaa aagaatacac
     4561 tgtgccatga atacacaaaa acgatacact tttatagtgt atcgtttttg tgtattggtt
     4621 aagaatcctt taaattcaat tagtgtatcg taaaaaagtt ggcacgcttt ttgcttatag
     4681 tagtgtgtgc taggaggtgg ttgttcacac agaaatgata ggggtttctg tgaagtagtg
     4741 aggaagaagg agttttgcag atggatattc gattggcacg tatagatgat cgtttaatcc
     4801 acgggcaagt cgcaacagtt tggtcgaagc aaacaggtgt tgaacgtatc attgtgatca
     4861 gcgatgtagt cgctcaagat aaattgagaa agtttctact aaaagaagct gcaccgccgg
     4921 ggatcacagc aaatgtaata accgtgcaga aaatgattca aatctatcat agtggattat
     4981 tatcacgagc aaaagtgatg cttttattca ccaatcccca agatgttgaa gcggttgtcc
     5041 gctgcggtgt acagttgaag tcgttgaata tcggcggtat gagttttact gaaggcaaat
     5101 caatgattac caattttgtt tcagtaaatc aacaagatat tgattccttt cgttacttga
     5161 acagtcaaga agtggagtta gagattcgaa aagtacctgc tgacaggaaa atccttttga
     5221 tggaactact agcgaaaatc aaaaaggtgt agcaagaatg gttgttggaa aaggtcaaat
     5281 aattctgttg taatggttag caattattaa tatttttgaa tttgttacaa caaaagtaaa
     5341 taggaggtat aaatatggta gggattatcc tagcaagtca tggacaattt gctgaaggaa
     5401 tcttacaatc cggttcaatg atctttggcg aacaagaaaa cgtcaaagcc gtgattttga
     5461 aaccaagtga aggtccagat gacttgagag ccaaattgga agaagcggtt gcttcttttg
     5521 ataatcaaga cgaagtgtta ttcttagttg atttatgggg cggaacaccg ttcaatcaat
     5581 caaacacatt attcgaagag cacaaagata aatgggcaat cgtcagcggt ttgaatttac
     5641 caatgttgat tgaagcctac gcatcacgct tttcaatgga atctgctcat gaaattgcag
     5701 cacacatcat tgaaacagca aaagacggtg taaaagtaaa accggaagaa ttagaaccgg
     5761 cagaagcacc gaaagcagca gttgaagacg cacaacctaa aggagcactt ccagaaggaa
     5821 ctgtggtcgg agacggaaaa atcaaatatg tattagcacg tgttgactca cgtctgttac
     5881 atggacaagt tgcgacagct tggacaaaag cagtgcaacc aaaccgtatt atcgttgttt
     5941 cagatgcagt atcaaaggat gatctgcgta agagactaat cgaacaagct gctcctccag
     6001 gtgtaaaagc aaatgttatt cctattagca aaatgatcga agtagcaaaa gaccctcgtt
     6061 ttggaaatac caaagcattg cttttatttg aaaatcctga agacgtattg acagctgttg
     6121 aaggtggcgt agacatcaaa gaattaaatg ttgggtcaat ggcgcattcg gtcggtaaag
     6181 tcgttgtaag taaagtattg tctatgggac aagaagacgt tgaagcgttt gagaagcttg
     6241 aacaaaaagg tgtgaaattc gatgtacgta aagtacctaa tgattcacgc gataacatgg
     6301 atgatatttt gaaaaaagca aaagctgaat tagcaaaagc gtaataaata atattaaaat
     6361 ttataggagg cttatcatgt ctattatttc aataatttta gtcgtattag ttgcctttct
     6421 agctggtatg gaaggtattc ttgatgaatt tcaatttcat caaccactag tggcatgtac
     6481 attgatcggt ttagttaccg gtaacctcga agctggtatc gtacttggcg gtacgcttca
     6541 gatgatcgct ttaggttggg caaatatcgg tgccgctgta gcaccagatg ctgcattagc
     6601 atcagtagca tcagcaatta ttttagtttt aggtggacaa ggtgttaaag gtgttccttc
     6661 tgcgatcgcg attgccgttc ctttggctgt tgcagggttg ttcttaacaa tgatcgtacg
     6721 tacaatcgct gttccaatcg ttcatttgat ggatgcggct gctgaagaag gaaacatccg
     6781 taaggttgaa atgtggcaca tcattgctgt atgtttacaa ggggttcgta tcgcggtccc
     6841 agcagcagcg ttgctattta tcccagcaca aactgtgcaa tcattccttg aatcaatgcc
     6901 agcatggtta acagatggta tggctatcgg tgggggaatg gtcgtagctg taggttacgc
     6961 tttggtaatc aacatgatgg ctacaaaaga agtatggcca ttcttcgtta ttggtttcgt
     7021 tgtagctgca atttctcaat taacattgat tgctctaggt gctttaggtg ttgcattagc
     7081 tcttatttac ttgaaccttt ctaaaatggg tggttcatca aataatggag gcggaagcaa
     7141 ctctggtgac cctttaggcg acattttgaa tgactattaa tcttgaagga ggaaaataaa
     7201 atggcagaag aaaaaatcaa attatcaaaa aaagatcgtt tagctgttgc gtggcgctct
     7261 accttcattc aaggttcatg gaactacgaa cgtatgcaaa acggtggctg ggcattttct
     7321 atgattccag caatcaaaaa attatacaaa acaaaagaag aacgttctgc agcattaaaa
     7381 cgtcacttgg aattctttaa tacacaccca tacattgctt ctccaatttt aggggttaca
     7441 ttggctctgg aagaagaacg tgcgaatggc gcgcctgttg atgatgtagc gattcaaggg
     7501 gttaaagtag gtatgatggg tcctttagct ggtgttggtg acccagtgtt ctggtttaca
     7561 gtacgtccaa tgctaggtgc actaggtgct tcattagcta tgggaggaaa tatccttgga
     7621 ccaatcatct tcttcttagg ttggaacatt attcgttggg cattcatgtg gtatacacaa
     7681 gaatttggct acaaagctgg ttctaaaatt actgatgacc tttctggcgg attgttacaa
     7741 gacgtaacaa aaggtgcttc aattttaggg atgttcgtat tagctgccct tgtacaaaga
     7801 tgggtatcaa tcaaattctt accagttgta tcaactgtaa aattagataa aggtgcttac
     7861 atcgaatggg ataaattgcc ttcaggtggt gaaggaatca agagtgcatt tgaacaagtt
     7921 aataatggct tagccctttc tcctgaaaag gtaacaacat tacaagacaa cttagaccaa
     7981 ttgattcctg gtttagctgc attaggatta acattgttat gtatgtggtt gcttaagaaa
     8041 aaggtttctc caatcgttat catccttggt ttattcgtag tcggtgttgt tggacacgtc
     8101 atcggacttt tataatccat aaaaatatag ctcgggcgtt gtcccgagct ttttttatat
     8161 agtatactgt tcataaacaa atatctggag ggagaaaatg gttcaatcaa tcaatacaaa
     8221 agtagacttg gtaattgatg ctacttcgtt tacgggtctg acagattacg ggcaaatcat
     8281 gataggtgat aatggttttg agttttacca tgcgcgagat agacgcaaat atatccaaat
     8341 tccatgggaa gaagtggatt atgtactagc atcagtcatg ctaaagggaa aatggattcc
     8401 tcgatatgcc attcaaacga aaaaaaatgg tacatacaca ttttcttcca aagaacctaa
     8461 aaaagtgctt cgtgcgatca gagaatatgt agatgaagat agaatggtac aatcattgag
     8521 tttctttgat gtagtgaaac gtggtattcg tagtatgttt aaacgcaagt aaaaaataaa
     8581 gaaaacttct aagaggaggt tttctttatt tttttacttt gcagaagaaa atatgaaata
     8641 gcaaaaccaa ttatttgtcc cctttaaatc ccatatgcta aaattgatta gcaaagaagg
     8701 aggttatatt atgagttggt tatggacatt gattgttgga gccgtgatcg gagcaattgc
     8761 aggtgcgatc accagtaaag gaaattcgat gggctgtgta acgaatatca ttgctggact
     8821 agtcggttca agtattggac aagcgatttt cggcgaatgg ggaccaaaag ctgcaggtat
     8881 ggcacttatt ccatctattt taggcgcagt gattttggta gcagttgtct catttttctt
     8941 tggaaaacga tcataagttt ttacaaaata gtaaactaaa aggagttgca gcgagactgt
     9001 gactcctttt tggctttatt tatttaaaat aaaaagaagt tttccggaaa tttttattta
     9061 actgtcgtgt acgaagaaaa gtttgctata atggaaaaaa gcgtgcaaag aaagagggag
     9121 tttcattatg atgctacgtg tagaaaaatt gcgcaaaaaa atgcaagaag aaaatttgga
     9181 ttcatttttg gttaccagtc cgtacaatct tcgttactta acgaacttta caggtacgac
     9241 aggattagct gttattactt tggaaaaagc attttttatt actgattttc gttataccga
     9301 gcaggcggca gcgcaggctc aagggtttga aattattaaa aatgtcggac ctatttttga
     9361 tgaggtagca aacttagtac gcaaagaaga actgcactca ttagcttttg aggaaacaac
     9421 agtctcattt ttagaatatt cggttttaga agaaatcatc gatgcggaat tagtacctgt
     9481 ttcacagatg atcgaagaac tcagagaagt gaaagatgaa gaagaaatcg ctattatcga
     9541 aaaagcatgt catattgcgg atatggcata tgatcacatc ctgaaaatga tccaaccggg
     9601 catgactgag attgaagtcg caaatcaact agacttttat atgcgttctc ttggcgcttc
     9661 aggtgtttct tttgatacga tcgttgctag cggattgcgt tcggctatgc cgcatggtgt
     9721 agcaagcaaa aaaatcatcg aacaaggtga cttgatcaca ttggactttg gttgctatta
     9781 cgaagggtac gtttccgata tgacacgtac attcgctatt ggtgatcctg gggaaaaatt
     9841 aaaagaaatt tatcaaatag tcttagatgc tcaattagca gttattgatg ctgcaaaacc
     9901 aggaatgact ggtgtccaat tagatgcagt tgctagagat tatatttcaa aacatggtta
     9961 cggggaagca tttggacatt ctacaggaca tgggatcggt ttagagatcc acgaaggacc
    10021 aaacgtttct tctcgtgcag aaaagcaatt tgtaccagga aatgtgatca ctgatgaacc
    10081 agggatctac ttaccaggaa tcggtggagt acgtattgag gatgacttgt tgatcacaga
    10141 agatggaaat cgtgtgttga ctcgttcacc aaaagaattg atcatcttat agtttcatca
    10201 atagaagaag taagcgtaaa aatcagtgtt cacagacttt gttatagaaa atcactcgat
    10261 ttaatgatac actatagaag aacttttaag ctgtaagaga taataaagtt gggtgttttc
    10321 tccaattcat agcagtttgc agctgatcgg cggcagtttt cttaccacgt gatcactatg
    10381 ccgcatcata gagaattcgg atgtatctcg tgcttaggca aagggaggaa taaataaatg
    10441 gcagatgaaa aaaatttgat tttaaacgca aaccaagatt taggagagat cgtgatcgct
    10501 cctgaagtca tcgaagtaat tatcgggatt gcagcttcta aagtagaagg cgtatacgga
    10561 atgcgcggaa cttttgccag caatgtcact gaattattag gacgtgcagc tcacggaaaa
    10621 ggtgtttact tagcaaacga ggaagatggc ttgaaagtag atctttactg ttatctagaa
    10681 tatggtgttt cagttcctaa agtagcaatg gaaatgcagg aacgggtcag ccagcaagtc
    10741 cttttcatga cggatatcga tttatctgaa gtcaatatcc atgtagtagc tgttgttcct
    10801 gaaaaattag aacaaccaac aatcgaagaa ctttttgaag acgaagagga agagaatgaa
    10861 taaagaatta tcaagacacg agattcggga aatggcattg caggctttat ttccattaga
    10921 cttcaatgca gacctaacaa aagaagatgc gattttcaac gcaatcgaat tagaccaccg
    10981 cgacatgatc aacgaagatg aatcagagtt tgttcctgtt tatcttgata cgctagttgg
    11041 cggtgtctgt gcaaaaaaag atgaattgga taaagtgatt gaaaaacatt taaaaaacaa
    11101 ttggcacatc aatcggatct caaaaatgga tttggtgatc ttgcgtatcg cgatttttga
    11161 aatgacttat gtgacagatg taccagcggc tgttgcttta aatgaagcaa tcgagttggc
    11221 aaaaacattt agtgatgacc gttcacgtaa attcgtcaac ggtgttttat ccaatgtatt
    11281 gaaagaatta gaagctgggg cgtaagtcct agcttttttc tatgaatcat cataaacctg
    11341 ttataaatcg ggaaaattct atggtagaat gaaaacacaa aaaatatctg ggagtggtta
    11401 gatggcagaa ttgattaacg gaaaagaatt agctgaaaaa atgcaggcag agattgctga
    11461 aaaaatccaa aaattgaaag ataatggtat ccatcccgga ttagtcgttt tattggtagg
    11521 ggaaaatcca gccagccaaa tctatgtaag aaataaagaa cgtgtagcaa aagaaatcgg
    11581 aatccattca ttggtagagc gttatcctga gacgatttct gaagacgaac tacttgcaga
    11641 aattgaaaaa tacaatcaag atcctagttt tcatggtata ttggtccaat taccattgcc
    11701 aaagcatata gatgaagaaa agatcctgtt agctatccgc cctgaaaaag acgtagacgg
    11761 ttttcatccg atgaatttag gcagactcct tgcgggtaaa ccggacaaga ttccttgtac
    11821 tccatacggc atcatgaaaa tgtttgaagc ttattctatc gatccggcgg gtaaacgagc
    11881 agtagttatc ggacgaagca atatcgtcgg taaaccgatg gctcagctac tcttgatggc
    11941 agatgcaact gttactgttg ctcattctaa aaccgaaaat ctggctgaac tggcacaaga
    12001 agcagatatt ttagtcgtag caataggacg tggacatttt gtcacaaaag aattcgtaaa
    12061 accaggtgct gtagtgatag atgtagggat gaatcgtgat gctaacggta agctgatcgg
    12121 tgatgtgaaa tttgatgaag tggagcctat tgcaggctgg atcactcctg tgccaaaggg
    12181 tgtagggcca atgactatca cgatgctgat gtatcaaacc gtaaaatctg ccgaagcttt
    12241 tggagcaggt gaatagatgg cacaagaata tttaactgtc actacattaa cgaagtattt
    12301 gaaaagaaaa tttgatgccg atcattattt agaacgcgta tatttaacag gcgaaatatc
    12361 gaatttccgt ttacgtgcca atgcccatca atatttcagc ttaaaagatg accatgcaaa
    12421 aatatctgct attatgttca aaggagcatt ccaaaaatta cgattccagc caaaagaagg
    12481 aatgaaagtc cttgtcgttg ggcgtatttc attatatgaa gcgggaggtt cttatcaaat
    12541 ctatgtagag cacatggagc ctgatggaat aggtgcttta tatcaagaat tggaagaacg
    12601 aaaagaaaag ctgatgaagg aaggcctttt tcaagggcct aaaaaaatgc tgccacgttt
    12661 cccaaagcga atcgcggtcc ttaccagtcc aagcggagcg gttatccgcg atatcatcac
    12721 gacggtgaaa agaagatatc caattgtcca attggttttg ttcccaacag ttgtacaagg
    12781 aaaccaagca gcggacaatg ttgtcaggaa tatccagaga gtagaagaga tgggcaattt
    12841 cgatacaatg atcatcggtc gtgggggtgg ttcgattgag gatttatggc cgtttaatga
    12901 agagcgggtt gctcgggcga tttatcaagc taatacgccg gtgatttcat ctgtaggaca
    12961 tgaaacagat accacgatcg ctgatttagt agcagatgtt cgggctgcca ctccaacagc
    13021 agctgcagaa ttagctgttc ctgttttgtc agaagagttg atgcgcattc aagaacggca
    13081 agctagattg cagcaggcgt ttgtacgcca gatccagcgc aaacaagaac ggttcgagcg
    13141 tgctcgacgt tcctatgtat ttcggcagcc tgaaagattg tatgaaggtc agaccatcaa
    13201 attagaccag ttgaaacagc gattatatca agctacacag caaatttatc atgcgaaaga
    13261 aaaacaaacg atcgcattaa gccaccaatt ggaacaagtg gctccgcttt atcgagttaa
    13321 agcagctcgc caagaaactg cttatctaga aaaacgctta gaagagaaaa tccaacaata
    13381 tatgaaacaa cagcagcagc gttttgctca agctgttcaa tctcttgatt tgttgagtcc
    13441 attgaaaatc atgggaagag gctacagcta tacgacgtta aatgatcaag tagtaaaaag
    13501 tgtcaccgag attcatcaag gggatttgct gacgatccat tatcaagatg gaatcgttaa
    13561 aggacaagta caagagatag acaaaggaga ataaaaatat ggaaaatcca acttttgaag
    13621 agtcactgca agaattagaa aaaattgtca tgcagttaga acaaggagac gttccattag
    13681 aatcagctct agattcgttt aaacgaggaa tggaattaag caaacattgc caagatacat
    13741 tagctaaagc agaagagacc ttgacgaaaa tgatgacaga atcaaatgaa gaagttgatt
    13801 ttgacggaaa cgaggaaagc tgagatgaga ttaactgact tttcagctat tcatctacct
    13861 gctgtagaaa aagaaatctt gtctttttta gatgagcata caacggatag aggactctat
    13921 gatgcgatga gttattcagt gaaagcaggc gggaaaagaa tacgtccctt attactttta
    13981 acggccgttg cttcctttga tgagcctatt gatgttcccg tctatcaagt agcagctgct
    14041 ttagaaatgg tgcatacgta ttccttgatc cacgatgatt tgcctgcgat ggacaatgat
    14101 gatcttcgta gaggaaaacc taccaatcat aaagtattcg gcgaagcatt agctatattg
    14161 gccggagatg gtttgcttac aggagcattc cagctaatca gtatggcaca cttaggtaat
    14221 tctcctaagc ttctgctgct tcagcaatta gctgtttgtg cgggatcaca aggtatggtt
    14281 gctgggcaag ctgcagatat cgagggcgaa tcgaaaaagc tttctttaga agaattagca
    14341 tttattcatg aaagaaagac agggcatttg attcgttatg ccttgctggc tggtggcata
    14401 ttagcgaagc aacctgaaga aatcttattg ctacttcaac gattagccga acatttaggt
    14461 ttagcttttc agataagaga tgatctactc gatgtgattg gtacaacgaa aacattaggg
    14521 aaaacagctg gtaaagatga acgtatggaa aaaaatactt acccgcgttt attaggccta
    14581 gaaaagacac gtgaggcgtt ggagattgag ctgttatccg ccaacaagat catagacaaa
    14641 ttagaagagg acgttttttc ttttgatggc gggctgatgc gccagatgat caagcaattt
    14701 gatgtggaga aatgagggaa agaatggaaa aagaacgcgt agatgtatta gcggtcaaac
    14761 aaggattatt tgaaacaaga gaacaagcca aacgttcagt gatggctggt ttgatttaca
    14821 acgaaaaaaa cgagcggttt gataaaccgg gagaaaaaat tccagtgagt agtgaattaa
    14881 gagtcaaagg taaaaaactt ccttatgttt ctcgaggggg attaaaatta gaaaaagcac
    14941 tcaaagcatt tgatctatct gttgaaggaa aaacattgtt agatattggt gcatccactg
    15001 gcggatttac tgatgcagct ttgcaaaatg gcgcaaaaat gagttatgct ttagacgttg
    15061 gctacaatca gctagcttgg aaaataagac aagatcctag agtcgtcgta atggaaagag
    15121 tgaattttcg ttatgcaaaa cccgaagact ttaccttagg aattccagaa gttgctgtta
    15181 tcgatgtttc ttttatttca ctaaaactga tgctgcctcc attacatgct attttaaaag
    15241 aagagggaga agtgattgct ttaatcaaac cccaattcga agcaggcaga gaagctgtag
    15301 ggaaaaacgg aattgttcgt gaccctcaga cccatcaaaa agttttagaa gacattttgt
    15361 catttgcggc acaaggtgga tatgatgtgc tggaattaag ttattctccg atcacggggg
    15421 gagaaggaaa tatcgagttc ttggctcact tgaggaaagt acccgaaagc ggaacaatca
    15481 attcagctat taatatggca gaagtggttt caaatgcaca cgaacagttt gaccataaat
    15541 aaattgtaac tgtgaaaatc aagtgagaag tatgcggatt cttctttatt ataccaagga
    15601 aataagctat cattgattaa gaagaatatg ctaaggagcg aagacgtaat gagaaaaaaa
    15661 gatcggcatc gtttgattac tcgattgttg agtgagcaag atatccgaaa gcaggaagaa
    15721 tttgttgaaa tcctgaaaag caaaggaata tctgttactc aagctacgat ttccagagat
    15781 ataaaggaac tgaaactgat caaggtaccg gcttcagatg gcggctaccg ttatagcata
    15841 ccagctgaaa caaacgaaga tgtaaatact aaattggaaa aactattaaa agacgctttc
    15901 gtggcagttg accaaatgga aaaatttgtt attttgaaaa cattgccggg aaatgcttcg
    15961 gcagcagcaa atttgattga taaacgttac aagaaagaat tattttcgat tatcaatgat
    16021 gacgataatg ttttgatgat tacacgaact gaagaccagg cagttttatt gaagaaagac
    16081 ttcctgcatt acctttaagt tgaggagcga atgtgatgct acaagaaatc agtattacta
    16141 actttgcgat tattccggaa ttgcggcttt cttttcacga aggaatgacc gcgctgaccg
    16201 gagagactgg tgcgggtaaa tccattatta tcgatgcttt aggtctgtta gcaggaggaa
    16261 gaggttcaag cgattatata cgtcaaggag cagaaaaatg tgtgcttgaa gggttgtttg
    16321 aactaccaaa acaagaagga ttctctgaac tgatggttga attagggatc gaaacagatg
    16381 aggacaatct gattgttcga cgggatatgt ccttaactgg aaaaaatgtt tgtcgagtga
    16441 atggtcatat tatcacatta gctaatctga gaagaatcgg cagttattta gtagatatcc
    16501 aaggacaaaa cgaacatcag gaactgctcc agcctgaatc acatcttgct ttattggatc
    16561 gttttggaga tgtagctttc caacagaaga aaaagagtta tcagcaagaa tatatctctt
    16621 atcgtgagct ggaaaaaagg gtacgaaaag tgcagcaaaa tgaaaaatcc tatgttcaga
    16681 gaatagatat gctccatttc cagcaagaag aaatagctgc tgctgatttg caagtcggag
    16741 aagaagagaa attaaaagaa gaaagagaaa aacttagcaa ttatcaaaaa attgctgatg
    16801 gattagctgc aggttacgga gcactgacga ataatgaaca aaacagtgta gatggtgttg
    16861 gcttggccgt ttcagaactg caagggatcg cccatctaga tgtggagtat gaagcaattt
    16921 atgaaaatat ccaaagtgct tactatttgc tgcaagatgc aatcggcgat atgagtcgtc
    16981 agattgattt attggagtta gatgagagtc gtttagaaga agttacgcaa cgtttagaat
    17041 taatccgaca gttgaaacgt aaatacggcg aatccattga gtcaatattg gcttactatg
    17101 acgaaatcac cgaagagcta gcttcttctg atttttcaga aggtcaattg gacaaaatga
    17161 aagaggaact agagcaaaaa gagcttctac ttcagcaaca agccgcagat cttcatgaag
    17221 cgcgtaaaaa aatcgcaaaa gaattggaaa aatccattct gcatgaattg aaaagtctgt
    17281 atatggaaaa cactgagttt gaggtacgtt tcttaaaaga agaaaataga caattgaatc
    17341 atgatggatt tgaccaaatc gaattttaca ttacgaccaa tccaggagag ccactgaagc
    17401 ctttggtgaa agtcgcttct ggtggcgaac tgtctcggat gttgcttgct ttgaaaacta
    17461 ttttttcttc tgagcaaggt gtgacaagta ttatttttga tgaagtggat acaggtgtga
    17521 gcggaagagt tgcacaggcc atcgcagata aaatttctca aatatcgaaa tactctcaag
    17581 ttttgtgcat cactcatctg cctcaagttg ctgcagtcgc cgactatcaa tattatattg
    17641 tgaaagcagt gattgatgga cgtacgcaaa cttctgtttc agagttgaaa acaaaagaaa
    17701 gagaagaaga aattgcacgt atgctggctg gaagtgagat tacaaaactc acactcgaac
    17761 atgcaaaaga actattgaaa ctcgcaaaaa ggacctgagc cacctcgcag tggttcaggt
    17821 ccttttcagc agctgatagc tatattttat ttttacatga cactcattac agcagtcaat
    17881 acaacagatc caatcgttaa aatcagcatt gtccaaatga caaattttgt tactttagca
    17941 aaagtacttg tttgtttttt ttcacgcatt gttttcaacc tcgtcattaa ttagttgatt
    18001 caagtgtaca atcttttttc catttccaca agagggcttt tttataaaaa cttccctttt
    18061 tttaaataat aggtagttac gatacaaata aataatgtta atagaactag ccatataaag
    18121 gcatcatccc tttcagcaat aggtaactta atgttcattc catagatact gccgacgatt
    18181 gtcggtatag ttaaaataat cgttaaagaa gttaaaattt tcataatatt attcagatta
    18241 ttcgatacga ttgctgaaaa agtctgattc atttgttcta ctagttttaa ttgaatgcga
    18301 gaagtagtca ttgcctgctc tgtttccacc aatacatcac gtaaatgatt tttcaaagca
    18361 tgattttctt ggaaaagttt attttgcgct agttctttca atgcatctaa attagcagaa
    18421 gtcgcttctc tgaaataaac gaggcttttt tggatatcca tgatttgata aagttgtttg
    18481 ttttcagtgg atacttgaag tttggcttcc aaagtatcgc attgagattg aagcgtagct
    18541 aaataactgt tgtaagagag tgtgacctgc caaatgaatt gaaagaagat attgagatta
    18601 ggcgaaatat cactttttgg aaaggtctgg ctaaagactt tctttaaaaa cagtggttca
    18661 tgattcgtaa ttgtgataag cttctttttg ggcgtcaaaa taatagagag cgggtatgta
    18721 tccacttgaa aataaccgct aggacttgtt ttagcaaaag gatattgtaa caataataac
    18781 gctggctttg tcaactttga ttgattgaat tcttctgtac gggaattttc tgcatcgtcc
    18841 aatatggaag tgatgtaatc tgacggaatt tcaaattgat gtgtcagctg atgaatctct
    18901 tcttgattag gacgttctac acaataccag atcgtttggt cagtttcctt tccggtatta
    18961 cgcagtttct cattatctaa tgtaaaatat ttgatcatga ttttcctcct gttgcctgtt
    19021 tcttttatta taacggatag ggaattggaa tacatggaat gtgtttgtaa gatatagaat
    19081 ataactgcat aaatttaaat aaaatgaaac agttgtgtaa agtatataca gtatacttga
    19141 agcaacgata aaaaaggagt ttacgttcat gggcacattc acaccactta tcttgttttg
    19201 gtatatttac ccggtaatcg ttttgtttgg ttgccaattt cttgtaaaat tattttcgtt
    19261 aaatcgtcgt tttaaaataa aagcccctga tttggcgatt ccttttttgt ggggcggtat
    19321 gcatgcattg tctagaaata cagggacaat ttctatctta ccgtttttct ttatttctgt
    19381 tttgctaatg ggaatttgta ttgctgtttt ccaagcatat tattatgaag aaattattta
    19441 tccgcgttat ttcaagatga cttggcgttt ggtttttctg ttgacaatcg tcttgtacgc
    19501 tgtcttgatc attgtgaaca tactttctta cctatgaaaa aaatagaaaa gctgtaaaaa
    19561 gtcttttaaa aggctttttg cagcttgatt tttaaaaaaa tgtttatgaa taaaaaaagt
    19621 tgttcccgga tttcccagaa aaggtggtag aaagtggggg attgtggtag actaatttta
    19681 gttagtggag gaatgggggg ctttcaatgt tgatgggtga attccaacat aatattgatg
    19741 caaaaggacg tttaatcgtg ccctcaaaac ttcgtgaaga acttggcgaa aagtttgttc
    19801 tgacacgcgg attggatggc tgtcttttcg gctatccgat gagcgaatgg gaaaatctgg
    19861 aagctaaact gaacgaaatg ccgttggcta aaaaagacgc acgtactttt gtgcgattct
    19921 tctattcggc tgccactgaa tgcgaacttg ataaacaagg acgaatcaat atacccagca
    19981 cgttaagaaa ttatgcagct ttgacaaaag gttgcgtagt catcggtgta tctaaccgaa
    20041 ttgaaatttg ggatgagaca cgatggcaag atttttctgc agcagcagaa gagaactttg
    20101 acgaaattgc tgaaagtatg attgatttcg gactataaga ataggaagag gctgactaat
    20161 gactgaaaca tttcaacact atacagtcat gttgaaagaa acggtagatg gattgaacat
    20221 caaaccggat ggcgtttatg tagactgtac actcggcggt gccggacata gtgaatattt
    20281 attaagccaa ctaagttcta aagggcatct gtatgcgttt gaccaagatc aaaaagcaat
    20341 cgatcacgcc aagctgcgtt tagcttctta tgtcgaacaa ggtatggtca catttatcaa
    20401 agcgaacttc agagaattag aagaacgctt gagtgagcat gtagataagg tagacggcat
    20461 tttgtatgat ctaggggttt cctctcctca gctagatgaa gcagaacgtg gatttagtta
    20521 tcatcaagat gcaccgttgg atatgcgcat ggatcagtca gctcctttat ccgcttatca
    20581 cgtaattaat gaatattcct accatgaatt agtaaagatt ttcttccgct atggcgagga
    20641 gaaattttcc aaacaaattg ctcgtgaaat cgaacgagta cgaaaaacaa aaccaatcca
    20701 aacaactggt gagcttgtcg aaatcattaa acaagtcatc ccagctcccg caagaagaaa
    20761 aggcgggcat cctgcaaaaa gaatttttca agctgtgcgg attgcagtaa atgacgaact
    20821 cggtgccgaa gaggcctctt tagaacaggc aatccggtta ttgaaagtca atggaagaat
    20881 cagcgtaatc acattccatt cattggaaga cagaattgtc aaaagtatgt ttaaagaata
    20941 tagtacggta caagatctac caccgggact tcctgtcata cctgacgaat tccaaccaga
    21001 actgaaagtc attactcgta aaccaatcct tccttcagag gaagagctaa cagaaaacaa
    21061 tcgatcacgc agtgcaaagt tacgtattgc agaaaaaata agaatgaaag aggagtagaa
    21121 tgatggcaga attaaagaaa atgcaagatt acgaatatga tttacctgaa ttggtggatc
    21181 agccggaaca acaaatgcct gattcttctt cgaatcaaga aatcattctt ccacaatcac
    21241 cggcaaaacg attaaagcag atttctgctt tggaaaaaat tgctgtggca agcgtggcga
    21301 ttgctattgt tgctttatgt gttttaacag ttatgctgcg cacaaatatc agcggagctg
    21361 aaaaagaaat cacgtcaata caaacagaaa tcaatgataa aaagcaagaa aaaacgagtt
    21421 tagaacaaga aaaaaacgaa ctttctcgta ctgaacggat taaacaaatc gcagaagaaa
    21481 aaggattgtc tattaatgac gacaatttaa ggaaagtgaa gtaaatgagt cttaaaaata
    21541 aaattcggcg gtttatggaa aagaaaaatc taaatccgat gaacaatcgc aaaaaagtag
    21601 gtatcatttt atttgctacg agtattggat tgttcttttt atttgccgtc cgtttctcgt
    21661 atatcgttat tggaggtcat gttgctggta cctcattagc tgaaaaaaca aaacagttgt
    21721 accaaggaag tgaagtagta aaagcaaaaa gaggaacgat ttatgatcgt aacggtgtgg
    21781 cgctcgcaga agatgcctcc tcttattcaa ttaaagcgat actctcaaaa acatatacct
    21841 ctggggataa aaaactgtat gttgaagaaa agaattttga taaaatagca gaaatcctgc
    21901 ataagaatct ttctatagac aaaaaagatg cactgaatat tttagaggac ggcgcaaaaa
    21961 aagagctgta tcaagttgaa tttggtagct atgggaaaaa tatctcccaa gaaaccaagc
    22021 aaaacatcga agcggacatg aaaaaagaag gtgtcgctgg tctttatttt gtcgaccatc
    22081 aggctcggat gtatccaaat ggcgtctttt cttctcattt tattggatac gcagttccag
    22141 acaaagatga gaatggctta gttggtaaac taggtttgga gtctgcttac aatgatatct
    22201 tgagcggtaa agatggtaag attatttatc aaaaagataa ttttcaaaat cctctgccag
    22261 gtacagtggc agaagaagaa aaagctgtcg acggacaaga tatctacacg actttagaca
    22321 gcagactaca aagttattta gaaacactga tggatcaagt aaatgaagaa tatcagccag
    22381 aagaattgac agcagtcctg atgaaagcaa aaaccggaga aatcttggca atgggacaac
    22441 gacctacttt caatcctgaa acaatggaag gattgactgg aaaagatgct atctggcgta
    22501 atttcttggt acaagatagt tatgaaccag gatcaaccat gaaagttttc actactgcag
    22561 ctgctatcga agaaggagaa ttcaacgaga atgaaacctt ccaatctgga aaaatccaag
    22621 tagaagatgc tacgatcaat gaccatgact ttggtgaaaa aggtgtgctg accatgcgtc
    22681 aagctctttc atggtcaagt aacgtcggga tggtcatact ggaacagcga ttaggcggac
    22741 gatggtataa ctatttacaa aaactgggat ttggacaaag tactcattct ggattagatg
    22801 atgaagtaaa cggtgcttta cctacattaa atattgtcga ccgagcaatg agtgcttatg
    22861 gacaagcggt aggtgtgacg aatttccaaa tgatgaaagc tttcacttct attgcgaata
    22921 acggtacaat gattcaacct cgatatatca gcaaagtggt ggatccccaa actggagaag
    22981 agcgaacaac tcaaacagaa gttctagggc aacctttttc aaaagaaaca acagaaaaag
    23041 tccgtgaata tatgagagat gttgtcgaaa gcgaaaacta cggtagtgct tatggtgtat
    23101 atagtgtacc tggatacaat gtatcggcaa aaaacggaac agcccaaatc gcttctgata
    23161 cagggggata tcaaacagga gatacagcct acctgtattc gattgtggag atggttcctt
    23221 ctgaagatcc agactatgtc ttgtatctaa caatgaaaca ccctaagaca tatgatcgaa
    23281 tggcattggc taaaatcgca aatccattga tgaaacgggc aatggatttt aaagaaactg
    23341 aagaagattc agatacagaa acaaaaacag aaaaagtatc cgtagccgat tatcgtaatc
    23401 ttgaagcgga cgttgcagca gctgatgctc aaaaaagtgg actgcaacct gtagtgatcg
    23461 gtaatggtaa aaaagtacaa aaacaatcta ctgccaacgg tgatcagttg atctctggag
    23521 aaaaactgat cctatatact ggtggtgata agctgatgcc tgacgtaaca ggatggtcaa
    23581 aagcagatat catgaagctg gggaaaatcc tcggtattga agttagtttt gatggagatg
    23641 gttattgtgt caaacaagaa cttgctccat atgaaaaaat cactgaagac aaacttagtt
    23701 ttactttaga agaataagaa gagaaatagg agagaaaaga gcatggaatg gacacaagca
    23761 ttgattccca ttgtcagcag ttgtgcaatg acaattgccg caatgccgct atttattggt
    23821 tattttcaaa tgaaaaagca aggtcaggcg attcgtgagg agggaccaaa gtggcacaat
    23881 agcaaagccg gaactcctac aatgggcggc ttagtgtttc tgatcggctc tattttgaca
    23941 ggaatttggg ttggagcttg gcaaaaacag ctaactccta ctcttttcat cttgcttttt
    24001 gtattagcgt tatacggagt aatcggcttt cttgatgatt ttataaaaat attcaagaaa
    24061 agaaacatgg gactgaactc gaagcagaaa ttgattggac agattctagg gggaatcatc
    24121 ttttatcttg tttaccgttc tgaaggttat ccaggtgtat tgaatttctt cggactagat
    24181 ctacctttag gaatcattta tggtattttc gctctcttct ggcttgttgg attttcaaat
    24241 gcagtaaatc tgacagatgg catcgatgga ttagttgctg gcttaggaag tatctctttt
    24301 gcagcttacg gtctaattgc ttggcatcag catcagtatg atgtattaat catttgctta
    24361 agtgttttag gaggtttact gggtttcttc gtctacaaca gaaaacctgc caagattttt
    24421 atgggagatg tcggttcatt agcgttgggc ggacttttag cggcaatttc tataatgcta
    24481 aaccaagaat ggacattgct tttgattggt ttgatctatg ttatggaaac agcaagtgtg
    24541 atgcttcaag ttacttcctt taagcttaca ggaaaacgaa tttttaaaat gtctccaatt
    24601 catcatcact ttgaaatgtg cggatggtcg gagtggaaga ttgatacagt tttttggttg
    24661 atcagcattg tgacttcgtt gatcacatta tggatcgttt ggtaggagat gacgggaaat
    24721 gaaaaaaata tcaacatatg aaaataagaa agtgcttgtc ttaggactcg caaaaagcgg
    24781 agtaagtgcg gccaaattat tacatgaatt gggcgcactt gtcaccgtta atgatggaaa
    24841 accttttgac gaaaatccgg aagcacaaga gctgctttct ttagggataa aagtaataac
    24901 aggtagtcat ccaatcgaat tgttggatga agaattttca ttgatggtca aaaatccagg
    24961 gattccctac agtcatcctt tagtagcaaa agcccaagaa atgggtattc cggtaattac
    25021 ggaagttgag ctagcttacg aagtagcgga atgcccaatt attgggatta caggaacgaa
    25081 cggaaaaaca acgacaacaa cgatgacagg actactactg aatgcaggag cagatcaagg
    25141 aattgcacgt ttagcgggta atattgggta tccagcaagt ggtgtagcgc aagaagcaaa
    25201 atcagaagat aaaattgtga tggaattgtc tagcttccaa ctcatgggaa tcacagattt
    25261 ccgccctcat atagcggtga ttaccaatat ctatgaagca catattgatt atcatggtac
    25321 aagaaaagaa tatgtcaaag ctaaatggaa ccttcaaaaa aacatgacag aaaaagatta
    25381 tctgatcctt aactggaatc agtcagaact acaagaatta gcgcaaagaa caaaagcacg
    25441 cgtactgcct ttctcgacaa aagaagtgtt ggaagacggt gtgtatgctg acgattactc
    25501 aatatactat aaaaaagaaa aaataatgga aatatctgaa cttggcgtac caggtaagca
    25561 taatgtagaa aatgcactag ctgctatttc tgtagcaaaa ttgtatggta tatcaaatga
    25621 agctatacga gaaacgttgc attttttcca tggcgtacca catcgtacgc aatatgtagg
    25681 agaaatccaa ggcagaaaat tttataatga ttcaaaagca accaatattt tagcgactaa
    25741 aatggctcta agtggatttg aaacgtctaa ggtcgtgtta ttggctggcg gattagacag
    25801 aggaaataca tttgatgaat taattccttc attaaaagga atcaaagcaa tggtcgtatt
    25861 tggccaaaca aaagaaaagt tgatggatgc tggaaaaaaa gcaggcatcg agacaatagt
    25921 aacagccgat tctgtagaac aagcagttcc tttagcatta gaaaacagta cagatggtga
    25981 tgtagtttta ttatcaccag cgaatgccag ctgggatcaa tacccaaatt ttgaaactag
    26041 aggaaacaga ttcatggaag ctgtgaaccg attaaaatag aaaaagtaga agcgagcgat
    26101 aaaaaatgaa aattttggtt acaggcggag gaacaggggg acatatttat ccagctcttg
    26161 cctttgtcaa ttatgtaaag actcaagaac cgaatgctga attcatgtat gtgggagcaa
    26221 aacgaggtct agaaaacaaa atcgtccctg atacaggaat gcctttccat accttggaga
    26281 ttcaaggatt taaacgaaaa atttccatgc ataacatcaa gacggtccga ttgtttctta
    26341 agagtatccg tcaagcaaaa aaaatcctca gtgattttca accagatatc gttatcggta
    26401 ctggaggata tgtttccgga gcggtagtgt acgctgcagc caaaatgggt attccaacag
    26461 ttatccatga acaaaacagt gtaccaggtg ttaccaataa atttttaagc cgatatgtgg
    26521 atcggatcgc tctttcattt aaagatgcgg cttccttttt tcctgaaaac aaagcagttc
    26581 ttgtaggtaa tcctcgagca caagaagtag cagatactaa aaaatcagat attttgaaaa
    26641 catttgattt ggatccagaa aagaaaacag tcttgatttt tggcggtagt caaggagcac
    26701 ttaaaatcaa tcaagcagta tcagtttttt taagtgaata tattccttct tcttaccaag
    26761 ttttgtatgc ttcaggagat agatattatg aagagatcct aaataaaata aatcctgaaa
    26821 tacaaaatat tagtgtccag ccttatatca aaaatatggc agaggtcatg gcttccagtg
    26881 atctgctggt ggggcgtgct ggtgcaactt cgatcgcaga attcacagct ctggggttac
    26941 cggcagtgtt ggttcccagc ccatatgtta cgaatgatca tcagactaaa aatgcaatga
    27001 gtcttgttca cgcaggagca gcaaaaatga ttgcagataa tgaactaaca ggtgaatcac
    27061 taagtcagac agtcaacgaa atcatgggtg atgaagaatt gcaaaagcaa atgtgccgag
    27121 cttctaaaga acaaggaatc cctgatgctt caaaacgtct ttatgactta gtaaaacaaa
    27181 taatcaaaaa ataaaggcgg tggtcttagt gagtaagaaa aaagaaccaa aaaaattgtc
    27241 tcatccgtct tctgatgaaa acaatttgac tccttggcaa aaggctaacc gaaaatatct
    27301 ggcagaacaa gagatgaaaa accaagagcc aaaaaaagaa gacataacat tagatacacc
    27361 cctttcagat tctgaagaag aaaaaacggt tcaagaggaa cagcaagaag aaagccagtc
    27421 cgagaaaaaa atcgaatttt ttgaagagat caagcaaaag aaaaacggtg gaccatataa
    27481 cggttctttt ttgaaccggc tgcccaattt aaaaagtcaa cggcacaaag tactatttcg
    27541 tcggttagct ttgatcatca ctgtattggg tataccgctg atttttttga tctattatgt
    27601 ttctccttat agcaaattac aagcagttgc agtatcaggc aataagacag tcaacagcca
    27661 agaaatcatc tctgatacaa aattgtcatt aggagaaaat gtttggggac agtattttca
    27721 tcgatctact tatatcgatc gccttaaaaa agcacagcca agaatcgaaa cagcaaatat
    27781 acatttcaaa gggatgaatg aattcgattt ggatgtaaca gaatataaag agattgcttt
    27841 gatcgcaaaa aacaatcaat actacccagt gattgaaaat ggaacagtat tagatgaaaa
    27901 agtagcaaat cctacaaaaa atctccctat cttggaagag ttcaaagact ctgcaaaaat
    27961 caaagaatta acaaagcaat acaatcagtt atcatcagaa ttacaaaaag caatttctga
    28021 aatcaagtac acgccaagag caagcaataa aaatctgatc caattgaata tgaatgacgg
    28081 caatcaagtt attgtaaata tcaataatct tgcgaaccaa atgaaatatt attcgcaagt
    28141 agccaaagat atggatgaaa aaggtgtgat cgacatggaa gttggtatct tctcgcatcc
    28201 ttacggtagc actcaagaaa cggaagaatc gggccaatcg gaagaaacaa ctgaaagtga
    28261 agaaaatgcg gatcaaacaa acgaatcaag tgaagaggca gaaacgcaaa aagcacaaac
    28321 acctggatcg tctagcacaa acggatcatc tgattcaaat gattcaagtg aaacaagtca
    28381 aatagaagat aatccaagta caactccgtc aagtttaaat gaaaattgat aaaacaactt
    28441 taaaaagtaa gaatgtactt tctaaaaacc agtaatttat ggtagaattg gaagcagtga
    28501 atatatctat taataagtat attttaaaac ggacgctagt tgttcgcttg tatatggaat
    28561 agtaagtagg agggaatccc attcatggca aaaacaggaa tgtatgtagg ccttgatatt
    28621 ggaacgacat ctgttaaagt tgtcgtggct gaatatatcg acagccaaat gaatattatt
    28681 ggagtaggaa acgcaaaatc agaagggatt aaccgaggca ttatcgttga tatcgataaa
    28741 acggtccaag cgatacaacg agcagtacga caagcagaag aaaaagcagg tatccagatc
    28801 aaaggcgtaa gtgtcggttt gccagcaaac atgcttgaag tagaaaattg ccagggaatg
    28861 attgcagtta acggagattc aaaggaaatc accgatgaag atgtcagaaa tgtggcttca
    28921 gctgcccttg ttcgttcaat acctcctgaa cgtcaaatcg tgtcaatatt gccacaagat
    28981 tttactgtcg atgggttcga gggaatcaaa gatcctcgtg gaatgatcgg cgtaagatta
    29041 gaaatgtacg gtctgttgtt tacaggacct aaaacgatca tccataacat acgtaaatgc
    29101 gtggaaaatg ccggattaat cgtcaacgaa atggtgatta ctcctttagc gctgactgaa
    29161 tcaattcttt ctgacggaga aaaagatttt ggtacgatcg tcattgatat gggtggcggc
    29221 caaacaacaa cggctgttat gcatgataag caattgaagt ttaccaatct tgaccaagaa
    29281 ggtggcgaat ttgtcactaa agatatctct attgtattaa atacgtcatt taacaatgca
    29341 gaagcgttga aaataaacta cggggatgca tacccagaac ggacatcacc agatgaagaa
    29401 tttccagtag atgtgattgg tcagtcagaa ccagtgaaag tcgatgaacg ctacttgtca
    29461 gaaattattt cagctcgaat ggaacagatt ttcaacaaag caaaagatgc attggaccaa
    29521 atcgaagcat tagagttgcc aggtggcgtc gtattgacag gcggagctgc tagtcttcct
    29581 ggtgttgtgg acttggcaca agaaatcttc ggcgtaaatg taaaattgta tgttccaaat
    29641 cacatggggc tgagaaaccc ggtatttaca aatgtaataa gtatcgtgga ttattcagca
    29701 aacttgagtg aagtgtatca attggcaaaa attgctgtta cgggtgaaac ctcagcagct
    29761 cgtcaaatgg tagttgaaca agaaacaaca aacacatatg agagctatga agcacctgaa
    29821 gaaacaatct acgatgagcc ggaaccaaaa gagtccggag aaaatgtaaa aaataaaatc
    29881 aagggtttct ttacaaatat ttttgattaa ttcatcctgg gaggaataag atatggaatt
    29941 ctcaattgat aataatatca atgacggcgc agtaatcaaa gtcatcggag tcggtggtgg
    30001 cggtggaaat gctgtaaacc gaatgattga agaaaacgtt aaaggtgttg aattcattac
    30061 agccaacaca gacgtgcaag cattaaaaaa ttcaaaagct gaaacagtta tccaattagg
    30121 ccccaaatat actcgtggtt taggtgctgg ttctcagcca gaagttggac aaaaagcggc
    30181 agaagaaagt gaacaatcct tacgcgaagc tttagacggt gcagatatga ttttcatcac
    30241 tgcaggaatg ggtggaggaa ccggtacagg tgctgcacca atcgttgcag gtatcgcgaa
    30301 agaattgggc gcattgactg ttggtgtcgt gacacgtcca ttcacttttg aaggaccgaa
    30361 acgtggccgt tttgctgcag aaggtatcgc tcgtttgaaa gaaaatgtgg atacattatt
    30421 aattatctca aataaccgtt tattagaagt tgtagataaa aagacaccga tgcttgaagc
    30481 tttccgtgaa gcagataatg ttttacgaca aggtgtacaa ggtatctctg atttgatcac
    30541 agcgccaggt tacgttaacc ttgactttgc tgacgtgaaa acagtgatgg aaaaccaagg
    30601 tacagcattg atggggatcg gtgtggctag tggagaagat cgcgtagtag aagcaacgaa
    30661 aaaagcaatc tcctctccat tgcttgaaac atctattgat ggagctgaac aagtacttct
    30721 taacatcaca ggcggtttgg atatgacatt gttcgaagca caagatgctt cagatatcgt
    30781 agcaaatgca gcaactggcg atgtaaatat cattctaggt acatctatca atgaagaaat
    30841 gggcgatgaa atccgtgtga cggtcatcgc aacaggtatc gatgaatcaa aaaaggaacg
    30901 caagtctagc cgaccagcta gacaagcaca aatgcaatca cctgctcaaa agactgtatt
    30961 agatatggat caagctaaac caacttcttc agaagaagaa aacagttttg gcgattggga
    31021 tatcagacgt gaacaaaatg ttcgtcctag agttgatgat tccaattttg acaatatcga
    31081 aaaaaaagaa tttgatacat tcaaccgcga agaaacaaaa tctcatggcg atgatgaatt
    31141 aaatacgcca ccgtttttcc gtcgtaaaaa ataaaggaga ggaagagcac atgattgctg
    31201 acaacttgca gaaaatcaag caagaaattc aggattcgtg tgctcttgtt catcgtgatc
    31261 cgaaagaagt tacattagta gctgtaacaa aatctgttga atccgctcaa gctgaagaat
    31321 tggttagagc tggcgttatg aattgtgcag aaaaccgagt agataaatta ttagaaaaga
    31381 aacaagattt atttgatttt cctgaaataa agtggcattt aattggtaat ttacagcgca
    31441 gaaaggtaaa attgattgta aatgaaattg attactttca tgcgttggac agtttaagat
    31501 tagcagaaga aatccagaag cggttagaga aagaattatc ctgttttatt gaagtaaatg
    31561 tttctggtga ggaatcaaaa catggaattt caccagatga gcttttaccg tttgtggaat
    31621 ctttagctgc ctgcacaaaa atcaaggttg ttgggttgat gactatggcg cctaaagaag
    31681 cttctgatga gcaaatccat aaagtgtttg gtacgctgaa agaattgcgt gatcttgttc
    31741 aagcaaaagg ttatgcccat gcaccatgta gtgaattaag tatggggatg agtcaagact
    31801 ttcaaattgc gattgaagaa ggtgcaacat ttatccgtgt aggaacagcg ctattcaaag
    31861 acgaataaag gaggaacaaa aatgccgctt ttaaacagag gagcaattgc taattttttc
    31921 ggattagctg atgaggaaga gtacgaatac caagattatc ctgaaacaac aaaaaaggct
    31981 gtacagccaa ctaaaaaaaa tacaacacag aatcaatcaa ctcattctgt atctgctgcg
    32041 aatactcatg aaaaacaaaa aacggcgact tcacgtcctg taacgcatga aagtattcag
    32101 ccggctgaaa agaaaaaagt aattgaacta catcaatcac ctacaaaaac tgtagcgaaa
    32161 gaaagaacag cttcaagaac ctctacacaa cctaaagcaa atcttgctgg aaaaatcact
    32221 gtaatggaac caagagctta ttctgaagct atggcgattg ctaaacgaat cattgctgga
    32281 gaagcaacct tagtgaattt tcatttagta gaagaaaaac aagcgagaag aatcgttgat
    32341 tttctaacag gaacagttta tgcactagat ggagatatca aacgtgttgg agatgagatt
    32401 tttctttgta caccgactgg gatggagatt gacagttcaa ccgctcaatc ttttgcagat
    32461 gcgaatttgt ttgatctgta agaggaggaa ctacgattta tactattgca ctattacttc
    32521 atttacttca acgggcagcc tatttctata gcattatctt gatggtatat gcattgctct
    32581 cttggtttcc aggcgggtat caatcagggc taggacgatt attagctaag atctgcgaac
    32641 cgtatatcag tttgttcgat cgtctgcctt tgaggattgg acccttggat ttcacaattt
    32701 taggggcaat cctgatcttg aacttagccg tacaaggttt agcacagatc gttatatgga
    32761 taactgtcca tttagtttat tgattgaagc aacaaaatct ttattctcag aatagatagg
    32821 aggggaaaat tttggatgca aatgtatacc agcactttcg ggcagatgaa cgtacattta
    32881 tcgattcggt aggcgattgg attgaacagg ttcaaggaca atatgcaccc tatctgaccg
    32941 aatttcttga cccaagacaa tcctatattt tagaaacact gattcgacaa agcagtgatt
    33001 tgcgtttcat gttttatggc ggatatgaac aggcagaaag aaaaagatgt ttgattttcc
    33061 ccgattatta cgaacctgta gaggaagatt ttgaaacagc attgtatgaa atccattatc
    33121 ctagcaaatt tgccagccta agtcatggga aaatccttgg aactttagtg ggaacgggga
    33181 tcaaacgctc ttactttggc gatatcatct cggacggtga tcgctggcaa gtatttattg
    33241 caaatgaggt ggatcatttt gttgctgcac aagtaacaaa gattggaaag gttgctgtac
    33301 gcttggaacc aatcaaatac acagaaatga ttatgccgaa agatagctgg acacaagaaa
    33361 gaggaacagt tagttccatg cgactagaca gtgtgatctc tgagatttat aatatttcca
    33421 gacagcggtc caagcagctg atcgaagctg gtaaagtaaa agtgaactgg acagaaaata
    33481 caagacctga ttttgtactt gaactattag atattatttc agtcagaggt tatggcagag
    33541 tccagatcca agaacttgag gggaagacga aaaaagaaaa gtacagggta ctgttcggtg
    33601 tattacgtaa ataaaataaa aaggtggttt actcatggct ttaactccat tagatatcca
    33661 aaataagaca ttcccgacaa aaatgcgggg atataatcaa gacgaagtag atgatttctt
    33721 agatttagtt gttcgtgact atgaggaatt gactcaaaga aatcgagaat tagaaaaagc
    33781 agtcaaacat tctgaagaaa aacttgagta cttcaatgaa ttaaaagatg ctttgaacca
    33841 atcaatcatc gtagctcaag atacggctga taaagtaaaa acaagtgcaa gcaaggaatc
    33901 cgaagtgatc gttacttctg cacaaaacaa agcagatgag ttagttgcga acgctgaaaa
    33961 acgtgcacat caattaacaa ctgatgcaga agaaaaagca agaaaaatct tgacagatgc
    34021 aacagaaaaa gcaagacagc ttgcgacaga aactgaagat cttaagaaaa aaacacgagt
    34081 attccatcaa cgtatcagct tgatgcttga gtctcaatta gaacaagtga aaagtccgga
    34141 atgggatgaa attttacaac cattctccag ctacgtgact gacagccatg aagtgatcaa
    34201 agaagtttta gcaaaacagc ttgacaatga aaatgatact gatgtaaact cagacacagg
    34261 agtcatagaa gcacctatga cggcatttga tacacaggct attgatatct cgatcgtgcc
    34321 tggtgaaaat gaaaacgagt agaacagaaa agcactttgt tattcttaaa gcgagccgat
    34381 gagagtggaa gttcggtaag acactgcatg gtgaaagatc ctctacttga gacctgcttt
    34441 tccgaaatta gagtaagaag cagcggctga cctcgttatt ggtcacagag agtttgcact
    34501 agatagatgc aactaaattt gggtggtacc acggcatgtt cgtcccttgc ggctgaacat
    34561 gcttttttgt gtccggaaaa caaataaagg agtgtatggt tgaatgaaaa tgaaagaaac
    34621 cttgcaatta ggaaaaacaa aattccctat gcgtggtaat ttgccaaacc gagaaggcga
    34681 gtggcaaaaa gaatgggaag aaaatcgaat ctaccaaaaa agacaagagt tgaacgaagg
    34741 aaaacctagc tttgttcttc atgatggacc tccatatgcc aatggtaata tccatttagg
    34801 acattcattg aataaaatca gtaaagacat tatcattcgt tcaaaatcaa tgtctggcta
    34861 tcgtgcacca tatgttccag gatgggatac acatggattg ccgattgaac aagtattggc
    34921 taataaaggc gtgaaacgta aagaaatgtc catggcagaa tacttggaaa aatgtcgtga
    34981 atatgcactt tcccaagtag ataagcaacg agcagatttc aaacgcctag gagttgcagg
    35041 agattgggaa catccttatg ttacattaga tccttcttat gaagctgcac aagtacgcgt
    35101 atttggtaaa atggctgaaa aaggctatat ttacaaagga ttgaaaccaa tttactggtc
    35161 tccgtcaagt gagtcttctt tagcggaagc tgaaattgaa tataaagatg taaaatctcc
    35221 atctattttt gtagctttca atgtcaaaga cggcaaagat attcttgatg aagatacagc
    35281 ttttgtcatt tggacgacaa caccatggac attgccagca aaccaaggta ttgctgtaaa
    35341 tccaaaattt acgtatgtat tggtggaagc cgatggccgt aagtttgtcg tagcgaaaga
    35401 tttgctagaa acagtccaat cagaaatcgg ttgggaaaat gtaacagttc taaaagaatt
    35461 tgctggacaa gaaatggaat atatgactgc aagtcatcca ttctatgaac gtgaatcact
    35521 tgtgatttta ggcgatcatg ttactttaga cgctggtact ggattagtcc atactgctcc
    35581 aggacatggg gaagatgact atatcgctgg tagcaaatat aaactatctg tagtgtcacc
    35641 tgtagactca aaaggattgt ttacagaaga agcacctgga tttgaaggta tcttttatga
    35701 caaagcaaat cctatgatca ctgatctatt aaaagaaaaa ggagctttgc tgaagctaga
    35761 tttctttact catagttatc ctcacgattg gcggacgaaa aagcctgtga tctatcgggc
    35821 aactccacaa tggtttgcat ctatcgataa attccgtcag aatattttgg atgaagtaga
    35881 aaaagtagag tgggttatcc catggggtaa aacacgtttg tataatatga tccgtgaccg
    35941 cggcgattgg gtaatttccc gtcagcgtgc atggggagta ccacttccga ttttctatgc
    36001 tgaaaatgga gaagcaatca tcacaccaga aacaatcgaa catgtggcaa aattatttgc
    36061 tgaacatgga tcaattatct ggtttgaaaa agaagcgaaa gaacttcttc ctgaaggatt
    36121 tacccaccca ggttctccta atggcgaatt tacaaaagaa aaagatatca tggatgtctg
    36181 gtttgattct ggttcttctc atgaagctgt tttacgtcag cgaccagaat tatcattccc
    36241 agcagatatg tatttagaag gatcagacca atatcgtggc tggttcaact caagtatcac
    36301 gactagtgtg gctatcaatg gtgtagcacc atacaaatca gttatttctc aaggatttgc
    36361 tttagatggt gaaggccgta agatgagtaa atctttagga aacatcattg caccagaaaa
    36421 agtgatcaaa caatttggtg cagatatcct tcgcttatgg gtatctagtg tagattatga
    36481 agcagatgtt cgtgtttcta tggatatctt aagtcaagtg gcagaagtat atcgtaaaat
    36541 cagaaatacg atgcgtttct tattagcgaa tacagaagat ttcgatccta aaaaagatac
    36601 tgtttcgtac aatgatttac gttctgtaga caaatatatg accgttcgat tgaaccaagt
    36661 aatcaaagaa atccgagaag aagggtacga caaatataac ttcatgcata tttaccgtac
    36721 agttatgaac ttcttgacgg ttgatctatc gtcattctac ctggattttg ctaaagatgt
    36781 agtttatatt gaagcagaag atgattatca acgtcgttgc atgcaaactg ttttctatca
    36841 aacagctgta gctttgacaa aattattgac tcctatcatt ccgcatacag cagaagaaat
    36901 ctggtcattc ctgaaagaag aagaggagta cgttcagtta agcgagtttc ctggttatga
    36961 agagtttgca aaccaagaag aattgatgga tacctggact gctttcatgg acttccgtga
    37021 taatgtctta aaagcattgg aagaagcaag aaacagcaaa ttgattggta aatctttgga
    37081 agcaaaacta actgtttatc caaaacaaca agttcgtgaa atgttaaaag ctttggatgc
    37141 agatattgca caattattga tcgtttcacc agactacttt gaagttatgg cagcagatga
    37201 acaagtgcca gataacgcta tggtatttga tgatgttgct attacagtgg aaaaagcaga
    37261 cggggaaact tgcgatcgct gtcgccaagt tcgtaaagat gtaggagtag atgaaaaact
    37321 tcctcatcta tgcggtcgtt gtgcaaaaat cgttgaagac ttctatcctg aagctgtagc
    37381 tgaaggattc gaagaaaagt aaaagggaaa agggggtgtg acatgttctt tgtcacaccc
    37441 ccttttgtta tcaatcgttt aattttccac gttcacgata ccagttatct ggttgccaga
    37501 tccattcgaa tccgtctttt tcaagtagtt cgaaagctgc tttaggtccc attgatccag
    37561 ctttgtagtt gggaaaatcc ggttgtgttt ggtcccaagc ttttcgaatg acatccacga
    37621 tatgccaaga ttgagcgact tcttcccaat gagagaagtt cgttccatca ccattcaacg
    37681 catctaatag taatttttcg taagcttctg ggctattttc aaccatttct gcactatttc
    37741 taaattccaa tttgattggt tccgtttcaa atccttgccc tacttctttc ccattcaagg
    37801 ataaagaaaa tccttcagtt ggctgaatat agatcgttag aacattaggt ggaagtgtcg
    37861 tatcgtcaca tggttcatcg acagatgttt tgaatacatt aacaggaact tgtttgaata
    37921 cgatgttgat ccgagtccct ttttcagtca aacgtttgcc tgtacgtaca tagaaaggaa
    37981 cacctgacca acggaagtta tcgatagtga atttgcctgc gacgaatgtt tcagtctctg
    38041 attgagcatc cactttgtct tcttcgcgat agcccttgaa ttgtacacca tccaattcac
    38101 cttgagcata ttgcccgcga acgaagtttt ctaacacttc ttcttcgtta taaatgcgga
    38161 tagctttcaa tgctttgatc ttttctgtac ggatttcttt ttcggaaaat gctactggcg
    38221 gttccattgc aagtaatgct acaacctgta aaatatgatt ttgcaccatg tctttaagtg
    38281 cgccactatg atcgtagtag cccccgcgat cttctacacc gaggttttcg ccaaaagtaa
    38341 tttggatatt gtcgatatag cgattgttcc attgagcctc aaaaatatta ttggcaaaac
    38401 ggatagctga gatgttttgg atcatttctt ttcctaaata atgatcaatc ctgaaaatat
    38461 cttgttctgg gaatacttct ctgatttgct ggttcaattc aaaagcagac tggtaatcag
    38521 aaccgaacgg tttttctatg atcaaacgat tgaagccatt ttttgtcata atattttgtg
    38581 atttcaaatg agaaacgatc gttccaaaaa attgaggtgc catagccaaa taatagacac
    38641 ggttaccgtt taattgatag tgtccatcta atcggtcaga caattctttt aatgtctgat
    38701 aatgcgttga atcatttaca tcatgggatt gatagtaaaa atggcttgca aaggtagttg
    38761 cttcttcatc tgaaggattc aatgcacgga ttgtttcttt gacaacttca cggtagtgct
    38821 catcgctcca gggacggcga gcggttccga ttacagcaaa atgctcgcct aaatttcctt
    38881 ttctgtaaag gcggaacaaa gacgggtaca atttacgctg ggctaggtca cctgtaccgc
    38941 cgaatatcgt aaacaataca tttttttcat tagacatgtg gatacactcc tttatatttt
    39001 atcgacaaaa atcgtgctgg ccgccttaaa gctgacgggg attttctttc tatcattttg
    39061 gatagtgatc ggtccttcat aagctgcgat gtcaacgatc tcatattctt cgttgatatt
    39121 caggtcaata gtgactaagt aatccaacaa ttctttttca tcaagcactc gtgcgatacg
    39181 cacttttgta ccgacaggat aggactccaa tgtttgtcgg cgttcttcat ggacaacttc
    39241 ctctttttta ggaatcgatc ctccatgagg acaatgttca ggatgattca aatagttttc
    39301 taaatgatct gcaagatgtt ccgaagtcac atgttccaat acttcagcat catcatggac
    39361 ttcattccag ctatagtcta aatgttcaac taaaaaaact tcccataagc gatgtttgcg
    39421 aatcagactg ctagcttttt gcagtccgct tgcagtcaat tgtacacctt gataagggga
    39481 atgttctaca agctcttctt tcacaagttt agaaatcatt tcactgacag atgcagctga
    39541 gacatctaga ctagatacga tttgtttatt gttgactttc gttgtatctc cacctagttc
    39601 taaaatgatt ttcaaataat cttctcgatt tggtgtcata ttcgatcatc ctttcatggt
    39661 aaaaaaccat cattagtaag tgtaacaaaa aaaacgttaa ttgactattt ttctaaataa
    39721 aaaacaaagg atttttagac gtttttacaa caaaaaacga aagatgatag agaagactca
    39781 ttctttcgtt tataaaggat atatatatac attgggaggg atctattttt cagataacaa
    39841 cttatatgaa gtgtctgcag attcgtcata aagagtttgt tcgggataag aaaagataag
    39901 ataaaaacca tactgatcac gtacgactaa acgatattca tctatttcta ccacagatgt
    39961 gccaagagac tgaccgttga tcaaaaacgt gtaatcagat gtaatctgta attgttgttt
    40021 ttgctggcta tcactaaaga accatgtacc ttgatacttt gagagtcctt ctgacttttc
    40081 cgcttgtttt ttctttttca agtaaataaa acttgagaga acggtaatga gtgaaccaag
    40141 aaaatagatc atttttttta tcaccaaatc actcctttat gagaaaataa tcgcatagac
    40201 atattctttc ttctttattt cattgtaccg aataaaagct aaaatttctc taagactttc
    40261 gactggtttt tttactgttt ttctacaaat tatgatagga tacatagtag gaagaaaggt
    40321 gacataattt gaagtatcag caagtggaaa tagctttttt tattgaccgc ccgaatcggt
    40381 ttatagcaca ttgtatgaaa aaagacggag aaataattat tgcgcatgtc aaaaatacag
    40441 gtagaggaaa agaggtcctg ataccaggcg ctgaagtggc tattgtattt gctcctggac
    40501 ctaaacggaa aaccgcctat gatctgattg ctgtaaaaaa gaagggtgac tggtttaata
    40561 tcgatagtca attgcctaat cggctggcaa ttgatggtat tttagacggc acgatccttt
    40621 taccaggatt aactggtcca tttacggtat acaagcgtga agtaacttat cttcactcca
    40681 aatttgatat ttatttagag acggtggtcg gacaaaaagc atttgttgaa gtcaaaggta
    40741 tgacacttga aaataaagcg attggtgctt ttcctgatgc gcccacactc agaggattga
    40801 aacatatagg agaattaacg tatgccgcac aagatggtta tgccgcttat gtcttgttta
    40861 ttgctcagtt cgaacatctt catctggcaa cgatccatga agaaatgcaa ccagcactag
    40921 ctgatatggt tcgacatgcg cagcaaagcg gagttcaaat cctcgcctat aattgtcaag
    40981 tatcggcaga tgaggtaact gtcaagcagg ccattccatt tgatgtagat atcccttttg
    41041 aagatcctat acaatagaaa gaaggtaaaa taatgatcaa cttaggtatt atcggaacaa
    41101 attggattac tcatcaattt gtccaagcag ctttaagcac aaaaaaatat gaattgacag
    41161 cggtatattc tagacatttg gaaaaagcac aggaatttgg ttctcattat gaaggggata
    41221 tcgaattcgc aacagatttg aagacttttt tcaatattac tcatatggac accatttata
    41281 ttgcttctcc gaatagtctt cactttagtc aagctaagca agcaattttg gcaggaaaaa
    41341 atgtgatagt tgaaaagcca gctttttcga cgccaaaaga aatggatgaa atcatccatt
    41401 tggcaaatga acacaatgtg tatttttttg aagcagcaag aaatatccat gaatcaggtt
    41461 ttaaaaagat tgccgattac ttaccattaa aagacgagat aatcggtgca aatttcagct
    41521 atatgaaata ttcttcgcgc tatgaccaag tattagatgg agaagaaccg aatatcttct
    41581 cgactcattt ctcaggtggt gcattgatgg atttaggtgt ttaccttgta tatgcagctg
    41641 ttgcttggtt tggaatgcca aaagaagtcc attatttccc aagaaagatt tctactggtg
    41701 tagatggtct tggatggggg atcttacgtt atgagaattt tgatgtatcg atccagccag
    41761 gtaaaatcgg tgattcttat ttaccgtcag agatttattt tgactcagga acgctagtga
    41821 tgaatggagt caatgcaatt gaacaagcac aatttcatga tcgcgcgcat aaagaaatca
    41881 ttgatttggc ggtaacagct gcagaaaatc caatggcaga tgaagcagag gattttgcca
    41941 atgtcatggc tcatccgaaa gatccagctt ggggattgtt gtatgaagag tggatcgagc
    42001 tagctagaaa tgtgaaccaa gtgatttatg atttaagaaa aaatggcggc atcaaattcg
    42061 atgcagataa tgaggaagat ttttaatgaa cgaatttgta caagtatttc ccgaaaattg
    42121 gcagaaaaaa tatgaggata aagggtttat ctcaccttct cttattcaac gagcagtttt
    42181 tcagccacta agtaataaac aaagtatagt agcggtttct cctacaggtt caggtaaaac
    42241 actggcttat ctttggcctc tactactaaa cgtggaacca ggtgaagcaa gtgcgttggt
    42301 catttttgct tcttctcaag aactagctat tcaagtagca gatgttgcac gtgaatgggg
    42361 aaaagacaaa gagttgaaag tccaatcttt ggtgggcgga gccaacgtca aacgtcagat
    42421 tgagggtttg aaggaaaaac cagaaatctt gattggtaca ccaggaagaa tattggaatt
    42481 gatgaaagca aaaaaaataa aagcacatca agtgaaaaca atggtatttg atgaagcaga
    42541 ccagctattt gacgctggga acagccaaat cattgatcaa attcttcatc aagctccaac
    42601 agagtatcag ctagcttttt tttcagcgac agcagatcgt tcccttgaaa gcattgaaaa
    42661 aatcactggg aaaacgtttg agacaattga cgtgacagca gaggacgatt ctcgaaaagg
    42721 actgagacat tactttttac gtgtaccgat acgaaagaaa gatgactact tgagacgtct
    42781 cacgcatata gaagattttc atggtctgat tttctttaat caactgactg aattaggcgt
    42841 aatggaagaa aaattgctgt atagaggtgt accggtagga agtctggcct ctgatcagaa
    42901 caagctactc cgaaaagcag cgctagaaca attcaaaaag aaaatggtca gagcactttt
    42961 gaccacagat gtggcggcta gaggtttaga tattacaggt cttccttatg tagtgaatgc
    43021 agaagttccg ttaagtgaag aagcttattt gcatcgttcg ggaagaactg gtcgaatggg
    43081 taatgaagga atagtaatta cactcgtaca agataataat ctaagagatt taaaacggct
    43141 tttacgtcca tcaaatataa cacttgaaga gattttttta tacggaggta agctgcaaac
    43201 tgagcagcca accaaagaag atgcagctcc tgcagtaaat aaaaagtatg cgaaaacttt
    43261 ttctggaaag gagcagaacc cagaatataa caaagaaaaa ataagaaaaa aagttaaaaa
    43321 taaatcaaaa aaagagagaa ataaaggagc aaggcgcaaa taagcgcctt tttatgctat
    43381 gattatgaaa acgggaacaa aattggttgc cagaggaggg gttatgtgaa agaacgtcaa
    43441 gaagagatct tgcagctatt gacagaaaac caacaaggat tgacagcaag tgatgtagct
    43501 gagcgcttaa ctatcgatcg aagcaatgca agccgatatt taagtgaact atacaaggcc
    43561 catcatattg taaaaaccgc tggccgacca gtcgtttact ctttgccaac ggaaaagtca
    43621 aaatctgatg aagtgcatgt cgactcttct acgcaagtga cttttgaaac actcgttgga
    43681 gaaaatgatt ctttaaaagt cagcatacag caggcaaaag ctgcgattct ttatccaccg
    43741 cgggggttgc atacgattat ttttggagaa actggtacag ggaagtcgat gtttgctgaa
    43801 tgtatgtatc attttgcaat cgattcagag atgctttctg cagatgcgcc atttgtttct
    43861 ttcaattgtg cggattatgc tcaaaatccg caactgctct ttggacacat ctttgggatc
    43921 aaaaaagggg cttacacagg agcagctcaa gatagtcccg gtctaatagc caaagcagac
    43981 ggcggtatat tgtttttaga tgagatccac cgtttaccgc cggaagggca ggaaatgctg
    44041 tttactttca ttgataaagg tatttaccgt ccgcttggag aaagtgcaca agtacatgaa
    44101 gcatctgttc agatcattgg ggcgacgact gaatcttcag aaagtttctt atctacgttc
    44161 aatcgacgga ttcctatggc aatcaccttg ccgaatcttg cttcacgttc actggatgag
    44221 cgttatgaaa tcatctctct ttttatcaaa caagaagcga atcgtttgaa tcaacgtatc
    44281 gatatcgaaa aagaagcgat tcttgccttc atgctttatg atgcggaagg aaatatcggt
    44341 caagtgaaac gagacttgaa actagtctgt gcaaaatctt ttttacatta ccgtactcat
    44401 catgagaaaa agctaatcat tcgaaaagaa gaactttccc ttcaagtaca aaaaggatta
    44461 ctgaaaatca aggaaatacc ggaacgtctc gaccgattca tggacagcaa aagtcagtat
    44521 ttgacatttg aaccaggatt tgctgatgtt gtctggtcac aagatccaga acgaaacatg
    44581 caggtctata acgatattga ggaaaaagtc acttctcttt ccgaaaccgg tgtggagaac
    44641 attgatctag agaccctcat ttcaaaagat gtggatgctt atttccagac atatgtcaaa
    44701 gaattgacta aaagttcgat tcccaaagat cttttgccag atgaaatctg gcggttaacc
    44761 aatcaattgt atgatgtggc tgaaaaacgg ttagaccgta tttataatga aaaagctcgt
    44821 tttgcttttg ctttgcatct gcaaagtaca ttggatcgtg tgagagaagg tcatatgatc
    44881 gtccacccag atttgaataa cgtacggaaa aattttaaga gggaattcca ggtagcaatc
    44941 gatctttcaa cgatcattga agaagaagaa caagttgaga ttccttttga tgaaatcggc
    45001 tttattagta tgtttctttc tatcaatcta ggagaaagtg agcctgttaa agaaaacaaa
    45061 gtagatgttc tcatattgat gcacggcaga cagactgctt caagcatgtt ggagatggca
    45121 caagaactat taggaacaaa agtagggaaa gcttttaata tgccactggt tatggaagtt
    45181 caaacaatgt atgaagaagt gttacaatat gtcaaaaact atcaagagca tttgacgaat
    45241 ggcctactct tgttaacaga tatgggatca ttaaacacct tcagtgattt gatttatgaa
    45301 gagactggca ttcggacgaa agctatcacg atgacaagta ccatgattgt gatagaagcg
    45361 atacggatgg caagtgttgg aagaagctta gaagatattt atcaaaatat ccagctttcc
    45421 tttgaatcga tcgtacgtga tcagttcaaa gcggaaaagt ctgaaacttt acagcgtaaa
    45481 aaagccgtaa tcgtgacatg ctttactggt gaaggagtag ctgccaaatt atatcagcgt
    45541 attatgccag tgattaatca aaataaggta gaactgatcc agatgcagtt tttagaacgt
    45601 gaatcattca aaaaacacat cgatgcctta ttggaagaat atgagatcaa agcaattgcg
    45661 ggaacagttg atgttgatta tcaaaatatc ccattttttt cagcctatga cgtttttgat
    45721 gatgaaaaac taaatatttt aaagcgtata gctgatgatg agatcccgac agctaaaatt
    45781 gtcgattcac ttgctggatc attaagcgat gtcttttcta ttgatgaact gatccgttca
    45841 ttgcaaaaga cagttcagca gatccagacc gatttgtcga ttatcgtgga acctggagta
    45901 gatactggaa tcgttatcca tttagccttc atgttagacg gattgatcaa acaagaaagc
    45961 catcggcaat ttgagaaact gtctattttc tcaaaaattt atcgtttgga aatggatatc
    46021 gttcgggcaa acttgatggc actagaacga aaatatcagg taaaaattcc agaagatgat
    46081 atcgcatttc ttacacaaat gtttcttgaa aataaaataa aaaaatgaac acactaatca
    46141 tactgtttac acactaaaca tctgtgtgcg cactataaaa aagagctaaa aagcatgaaa
    46201 acgctatttc agctcttttt tttattggca tgcttcttgc gttatataaa agtgtaaaaa
    46261 aataaaagga gtgttaaaaa tggcaaaaaa aacaatcatg ttagtttgtt cagcagggat
    46321 gagtacgagt ttattggtca caaaaatgca aaaagcagca gaagaaaaag ggatggaagc
    46381 cgatattttt gcggtctctg cctcagatgc agataataat ttagaatcta agaatgtcga
    46441 tgtattatta ttaggtcctc aagtacgttt catgaaagct caatttgaac aaaaacttgc
    46501 gcctaaaggt attccattag atgtcatcaa tatgcaagac tatggcatga tgaacggaga
    46561 aaaagttctt gcacaagcag aaaatctaat gaaataaatc aagtatgcag ttgggggtat
    46621 aacaacgtgg aagatcaaca aaatctagaa gccatcatgg ggttaatcat gtttggcggt
    46681 aatgcaaaga gcgatgcaat ggaagcgatt gcggctgcta aaatcggtga ttttgagtta
    46741 gcggatagga aaatcgctga tgcagaagaa tcacttatac aagcgcatca tgcacaaaca
    46801 gacatgttga cacaagaagc acaaggaaat catatgcaag tgacattatt gactgttcac
    46861 agtcaagatc acttaatgac atctattgcg tttactgatt tagcaaaaga aatcatcgaa
    46921 ctttatcgtc gcgtatacag cgaataaata caacttcttt tttgaacgga agaagaaaaa
    46981 tttttgaacg gattttttat tttgttataa ggagaactct ctttatataa aaaacttata
    47041 ggaggaagta aaaaatgaac ggactatcaa gttggatgga gaaatacatc ctgccggttg
    47101 ccgcaaaaat cggagcgcaa aaacatttag ttgctttgcg tgatgctttt atcggcacac
    47161 tgcccgcaac aatggcggga tcagtcgctg taatgatcaa tgcaattatt cgtgatttac
    47221 cgcaacagtt taacagtacc tatgctgaca gtttagcagc agacaaagga atctttgccg
    47281 tattgaatgt catcatcgga atcaatggtt ttgtctggaa cggtacacta gcaatcgccg
    47341 gattgatctt tgccttttct tgggggtata atcttgcccg agcttatgga gtaaatgatc
    47401 tagctggggg gatcgttggt ttagctacct tgattcaagg tatttccttt ggtccagcat
    47461 tatcagcagc attagatgtg aatgttcctt caaatgtcgc agatgcaatc aatagttctg
    47521 agattggtgc aacgattgca gatggcacac tgtcagttgg attatggggt tggctaaaac
    47581 tagatcattt gaatggaaac gcttatttta cagttatgat catgggagct atttcagtca
    47641 ttattttttg taaattgatg cttgccaaca ttacgatcaa aatgcctgat tcagtaccac
    47701 cagcagtatc taaagcattt gcagccattt taccagcgac gatcgcttta tacgtcattg
    47761 ctattatcaa ttatatcgta ggtcgtgtag ctgatgggca actgatcatt gatttggtgc
    47821 aaaaatatat tgcagaacca ttcctaggat tatctcaagg gttgggagca gtattgatcg
    47881 tcacagtatt tgttcaagta ttctggttct ttggtattca tggaccaaat gtattggcac
    47941 cagtgctaga gggaatctgg ggacaagcac aactaatcaa tattgatatt ttccaaaaag
    48001 gttataacgg aaaaactggt acaccagccg tgttagatgc aatcgaagat ggaaaagctt
    48061 atatgtgggt ccgcggatcg ttcgatgctt ttgcatggtt tggcggatca ggcggaacga
    48121 tcgtcttact gatagctatc ttgattttct ctaaacgtgc agattatcta acagtagcta
    48181 aattatccat tgggcctggt atcttcaata tcaacgaacc agtgatgttt ggtctgccaa
    48241 tcgtattgaa tgcaatcatg tttatcccat tcttgattgc tccagtagta gcaacagcaa
    48301 ttggatggac agctacttat cttggcctag tcgctccggt atcgcagcaa gtcacatggg
    48361 tagtaccgcc gttcttattg tcattcttag caacaggagc ggattggcgg gcaccgatcg
    48421 taacattagt atgtatggtc gtgactttct tgatttgggc accatttgtc atctctgcaa
    48481 acaaaatgga ccctgccgca ggcgaacaac aataagatga acgtgaggag cgggacgctt
    48541 taagtttcgt tcctcataat gaattttcta ggaggaactg aaatgattac aattgccagt
    48601 gcaatgcaac aagatgaaat caaagaattg ttagaaggat acaatgaaga aggaatgact
    48661 tttacattta aagaaaaaca aggaatcaag ctgttctttg aaacaagtgc agaagatccg
    48721 gaagttgcgg ctaaaaaagc aaaggaacta atcaaagcac agccttgggg aacagtcctt
    48781 tattttcaat caacagctgt ttagaaaatg gtttaaaaag ataggatggt tgagatgata
    48841 aaaaacggtt tatttttatg tagtattggt tctttgatcg tgttgtatag tttgaatcca
    48901 cattcgcaaa ggtatgattt gtatagtatg gtcacaggtc tttttctaac aggattagga
    48961 atctatttct tcatgaaggg gaaaaaaaga gaagaagcaa aggagagaaa taactaatgg
    49021 aaatcacgaa aaaattaaat attccagcat cgttttttta cgataaagtt atggactctg
    49081 tccttttcga tgtacgtaaa gcgaccggca aatcagtaac tagaaaacag ctgaaaaatt
    49141 tggagtacgt caaacaattc tcgcaaaata accgggctcg cataaaaatc gaagaagtca
    49201 ttgaaaacca gtcttataag tttcgtacat cgacaacgaa gaatgaattc gtcgttcatt
    49261 atcaaatcaa accattggac gattcgacct gtgaggttca ttacacagaa aaaatggagt
    49321 cttatggcat gcttcaaaag ttgaatgata tgcttttagg aacaatcttg atgtatttta
    49381 aacggagacg tttcaaaaaa atgctagata tgatcgaagc aacgtattaa atcaatgaaa
    49441 catggtacta tttagttatt gaaaaatgaa gtaagctaga aggaattttt cataggaaga
    49501 tagatctttc ctgcgaatcc tcactagctt ttttgtagga aggggcagca aaatgacaaa
    49561 caaagtaaga gagctaggtg tatcttcgat tgaggaaatg tttgatttag ccacttatgc
    49621 atttaatggg gcagatacac ctgaaaggcg agaacgtttt cgtacacttg cggagaattc
    49681 ttggaattac ggattttttg atgaggagga tcggctaaca agtcaagtca tggcgacccc
    49741 ttttccagtg aatttttacg gacaagagta cctaatggcc ggcattggct atgttgcttc
    49801 ttatccagaa gcaaggggac aaggcgggat caatcagatc atggaaaaga tccttgaaga
    49861 ttgccgtgat cgtaaagtaa gcttatctta tctggcgcca ttctcctatc ccttctatcg
    49921 gcgctatggc tatgaacaat catttgataa aatcagttat caactaaaca gtcgtgatgt
    49981 gccgtttatc aaaaaaaaat ctggaaaaat aaagcgtatg gattttgaag atgcaaaagc
    50041 tgcaatcaga agaatttatg aacagatgcc ggaaaaccaa cgagctggtc tgaagcgcga
    50101 agactggtgg tatacgtata aattcaagca aaaaggcaat taccagtttg ctttgcattt
    50161 tgatgataat gaggaagcaa cgggatatat cgtttatcag cttgcaacgt cttcctttat
    50221 tattgcggag tggggatttt tggatcatga tgctttttgc agccttgttc gcttcgtaag
    50281 ttctcacaat ggtgcttttg aaacatttga atattcatgc ggctacggcg gtaatgatca
    50341 aaattatcta ttagaaaatc catttgcttc tgtaatgatc acaccttata tgatggcgag
    50401 gatcgtagat atttctttgt ttttggaaaa ttatccattt aaaaagagac aagctgcatt
    50461 tgccctacaa atagaagaag atcattatgc gaaatggaat gaaggaatcg tggaagtaac
    50521 aatcgaaaat ggaaaaaatc atctctcaaa agtagaacaa acaaaactcc caatcgttcg
    50581 aggaagtatc caacatatca cgcagctatt attagggtat cgtaaagtgg aagagttggt
    50641 attccaagaa agaatacagg tgacaaaaga atatgaagaa acgttaagct caatcttgcc
    50701 acagcaacag ccaattctta atgactattt ttgataaaaa acgggtgatg acaatatttt
    50761 tgtcaccacc cttttgtttt tcatttggca tttgaaggaa aatgttaaag taaatcctct
    50821 tttttcgtaa atttgaattt tttgttttct tttgttttag ggttttcttt tttgtggtct
    50881 tggattgctt ctttcgtaat cttttcccga ttttttttag atgaatctaa gcgttctgcg
    50941 tatacttttt cttttggctt atcattcatt ggaaaggacc tccctacatt atttcattct
    51001 acctctagtt tatcatctgt taaggactag tggaaacgtt ttgcctaact tataagctga
    51061 tttttttagc agataagctt gcaagtaaaa aacaaacaag ctacaattga tttattgaaa
    51121 ttgttcctgt agctcagtag gatagagcaa tcgcctccta agcgataggt cgctggttca
    51181 attccagtca ggaacgtata aataacccct gtatcctttg cggtacaggg gtttgttttg
    51241 tatttgtgcc aaaaatgtgc caaactagtt atcattttta tataaactat cgaacacagt
    51301 attgattttt tctttatcct gatcttcaag ctctcgaaca atatgaagat aagtagacat
    51361 tgtagtttct aaactgctat gtcctaaacg tttcgatacg ctaagtatat ttactccttg
    51421 ataaagtaaa atagatgcat gtgtatgcct tagtccatgc aaagtaaatt gcttttcaat
    51481 ccctaattct tttaattttt tgcgcaaata tttgctgacg gcgtttgatg aaactaatcc
    51541 attttttaag ttgaaaaaaa caaaattatg agggtttttg atttcaaaat tctcgaataa
    51601 ttctttttga ttgattttaa acttttttaa gagatcaatc gtatgtttat caatggaaat
    51661 tttcctattt gaagtttcgt tttttgtttt tccccattca tttaatttat aattccatgt
    51721 tttattaata gtgatgattt gatcttcgaa atcgatatct tcccatgtta atcctagaag
    51781 ttcagcaaat cgcattccag tggcaccagc aactaacacg agcataggag aagagtactg
    51841 cgcagaaagg ttttcttcta cgagtttcat taaagattta aattgatcat aatctaaata
    51901 tttatcttct tttggcttca atgaatcttt tcctttgatt actgcttttc tagttggatc
    51961 aaacggaatt aatccttctt ctacggcatc tttcaacgac gctctaatat ggttattaaa
    52021 cttaataacg gtagatttta catggtcttt agcatactta tttaaaaagc gttgatatcc
    52081 cactctatct aaatcagaaa tcaataccgc tggcatatat ttctttatgt tcattaacgt
    52141 atcttcgtat tttctataag tgataggaga tactgttcct tctttataaa gttgcatcca
    52201 atcctcaaag taatctgata ataatagatt tttgcgatcc cctttaaggc ctttgttcaa
    52261 gttatattct aattcgttgg cggcatcttt tgcttctcct tttgtcttaa atcctgattt
    52321 tcttatcttc gtgtattttc cgtcatcttt tttgtatgaa atttcgtatt gccaactatt
    52381 tccacgtttg actaatcttg ccataattga atcagctctc tttctctgat acaataggaa
    52441 ctataaagaa gcccattgtt tgggttttat tattttttgc acatcctttt tgcttgccgg
    52501 cgcaaggatg tgctatttgt cgttttaatg gtataattgg atgtgtatta gatcatccaa
    52561 tcagaggtgt ttattatgat taaagtgatt tttaaaagaa taactgaact tccagagttt
    52621 agattatttg ttgattattg gtatgtctgg ttttttattg ttgcattgct gataggtcta
    52681 gatgtcatat tagaaagaaa acttaagtaa gagttgagtt aataaattga attcctaaat
    52741 gagatatttt gtagcccata ttttgtttgc cgacatcacc taatactatg gagctaatcg
    52801 ttttttctaa cagaccaaaa tcagataatc tatttaagct accatctatt agctcttgtg
    52861 aatagccaga catgctgata tttccagtga aattttcgtt tccacgactc attaagcatg
    52921 ctaacaattg aatctcaatc gatgttaatt gattcagtac aagaagataa tactcctcgt
    52981 tatcccatga agcgctgtta attcgaagta aacaattctt ataaagattt ttatacatat
    53041 ctattttatt ttgtgccttt gatttttcta cctcgtcatt tatcccttcg aatattccaa
    53101 tgagttggtc cttgttctct aagttgaaaa catcttctgg aatttgatcg cgaatgtttt
    53161 ctaatgattc gtttaaattt ttgtagaatt tctcgatgcg tttgaaacgc ttctcgtttt
    53221 tagacccaaa ataaagtgac tgcacaacgc caccaatata aggaattgct ccaataccgc
    53281 cttcaactat taattcaaga tattcttttt tggttagttt ttcattgcta ttatccatag
    53341 ttacctccta ttttgtcatt tcctttacaa gcattgtgac tcctgatggc actcttttgt
    53401 ataggtttta ttattgtgca caatctaact cttagtgggg cgtggttcat ttatttttta
    53461 cttactttac tattaatcat atcccattga gcataggatt tttctatgtt cgatcctctt
    53521 gaactaattt ctcctgtaaa agttacttta tcgccctttg taaaggtatc agcattgttt
    53581 aagtccttcg caaaaattac atatgaaact ttaggtgttg cagaaatatc attccaactt
    53641 ttatcatcgt actctttgtc tgctataatg gctattctag tagtcattga ttcgataaca
    53701 gttccttcaa aagtatatgt tttaccacta atatatttag taaaagctgt attttgctca
    53761 gtagctggag taatagaata ataactatct aagaaagcac cccagtcatg attatttgtc
    53821 tctaaaaatt cttcaaattg agttaggctt ttattgctgc tgttagatgt agtagtttga
    53881 gtatcagatg atgagctttc ctgtttgtta ttgtcatttg cctcgtttga tgaggaaagc
    53941 gagaaaccta cggtagtaaa aataatcccg ataataagga gaatcatagg tgttttctta
    54001 tttgtttttt tgataaatct tacaattaac atgattaaac ctataataaa taaaacaata
    54061 ccagtaaaac caaatatacc gtccattaat agatcctctt tctcttttga tattgaatat
    54121 tataaaccaa gcaattcttt tttcttaaaa tcgaattctt cttgattaat aatcccttca
    54181 tctaacaact ctttatactt tttaatttca tctgcacttg aaatttgtgt ttctttggaa
    54241 ttattatcta atatagattg ttgcttctct atatattttt ttaaattttc catttcattc
    54301 caatattttt ttgtaaacat aacggtgttt tcatctttcg tggccgctaa tatacctccg
    54361 cgactttcgt ttccgcctag caaggtaaat tgtatataac cattactcat acctggtttt
    54421 tttaattgta cggctgataa atttttaaag gggatagttt tttctccttt aataccttga
    54481 ttaactaaat ttataaatcc ttttctaata attgaaatag aatcatcagt tactttaatc
    54541 aaggtttttc ctggagattt tattaaaatc tctttttcca ttttttcttc ctcatttctg
    54601 tgatatgatt ttttttgtag aagctcatat atgaggaaag agcccgtgtt gcagcacggg
    54661 cttttttaat gttttgctga aatcggtttt tttaataatt cttgatgtat tcatacatat
    54721 tgccttgcgt aagaatattt tttcttaaaa tagcattggc agacagcata acaagtgtat
    54781 ctgagcttat tctgaataga ataatactcc ataaattttt cgagattaaa ctgagattca
    54841 tcagtcagtt cgttctcaat atagatattt aataaaatta gaatagctat tttatctgct
    54901 tctgtttcaa attttgagtg aaaagttgta gaagtatcgt acaaaactga aaattcaaaa
    54961 tgagaggcgc tgaaatgtgc aagttcatga gataaatgaa aggcttctgc agtttcaccg
    55021 tatagatttt cattcaaaaa aatgattctg ggttttggat agtagaaacc aggctctttc
    55081 atctccatat aaactacttt caaattgtat tcgctcaaca tttctttcaa tttcaaatac
    55141 atacaaacca tcactccaac tattcatttt cctctaaagc tttagcaatt gcaatcgctt
    55201 tacgcattgt ctccttagat atttcttttc catcaaaaga aaaaacagta tcgtcttctg
    55261 ataaatccac atgtttaggg gtttctcttt cttctctacc tagaaggtag tctacagaga
    55321 catcgaaata gtcagcaatc cgacttaatt catctgaatt aggagtatta tttttccact
    55381 ttgctagata accgttagaa tatccaaaat taatttctaa ctgccgtata gatatctttt
    55441 tcctcttcgc caagtctttt attatttcat aggtattcat cgataaaaca acctttctaa
    55501 atgtttacaa aaaaagttta gaaaaatacg cagaaataat ttgactaatt ctgagtaatg
    55561 agctatacta tatcttgtaa acagatttaa caactaaaaa gacaacaaaa aacactattg
    55621 atatgtaaat gcagaccgcc aagaaagctt taaaatcaat gtttttatgt cttatttaat
    55681 tatgctctta gtatagagta ttactcagat actgtcaatt gaatttagaa aaaagttgtt
    55741 aaatttgttt acgaatataa aagaaaggaa tgagaaatat gaacacaccg caaattttta
    55801 atttcgaaca aaacgaagtt cggacaattt tagtaaatga tgaaccatat tttgtaggca
    55861 aagacgttgc gagtgttttg ggttattcaa acactaaaga tgctttgtcg cggcatgtag
    55921 atttggaaga taagatgggg tcgcgaatca cgacctcagg tcaatcaaga gagatgacaa
    55981 tcatcaacga atctggtttg tacagtttaa tcttaaaatc aaaacttccc tctgccaaaa
    56041 aatttaaacg ttgggtaaca agtgaagtgt tgccagcaat tagaaaacat ggaggttatc
    56101 taactccaga aaaagtagaa gaagctttgc ttaatccaga tacaatcatt caattagcaa
    56161 ctcaactaaa agaagaaaga actggaagat taatcgcaga acaaaagatt gcagagtacg
    56221 aacctaaaat ctcctattta gatagcatat tatcttctac agattcagta acaattagtc
    56281 agattgcagc agattatggg atgtctccac aacagatgaa taaattactt cataaactag
    56341 gtattcagaa aaaagtcggt aaccaatggt tattgtgcaa aaaacacatg aaccaaggat
    56401 acacaaaatc tcatacaact gagatcccga aagccgatgg tggcactaaa attgtaatga
    56461 ataccaaatg gacacagaaa gggcgtctat ttatctacga attactaaaa aaagaaggat
    56521 attaccctca aatggattta gaggaaattg gttagaaagg agttttagta tgactgacat
    56581 tgcagaaatc actcaacgag atagagaaaa aatcaaagaa tatgtcgaaa gttcaaagtt
    56641 cttaacttac accatgcttg ctgaaagatt tggaattagc aaaagctact tatctttaat
    56701 tttaaacggt aaaaagactt ctgcagaagc aaacagaatt atagattcga ttatcactat
    56761 gtacgaattg taaagggagg aacagctaat gcaatatcta gaagcaaaaa tcccaattcc
    56821 agaaggctat gtaattatct cccaagtgga ttatgaggag ttaaaaaaag ctgatgatac
    56881 tggtagatgg atgacgttgc cagaagtgct agaacggatt aacagaaaat atgattggtt
    56941 tacttctaga gttttaaaga acccaagata tagaaatatt atcgatatcg agaaaaacaa
    57001 aaatggattt gtctattatc cagttgaagg aagagacaca tatctatttt taagaagtaa
    57061 aacacttgaa tttttagaaa caaatttttc ggaaatctta aggaggcaag cggatgggaa
    57121 aatttaatag agcgctagtg ttcagcgcac cgctaatcat ctacgcttta ggactttggg
    57181 gaagcaggca agcgttgata ggaacgattg tttacatggt ttggattttt atggggcttg
    57241 atgaagctga agctgagtac agagcgaaaa agccaaccga gggggctgac taaaaatgaa
    57301 tagaaaagag aaactagaat gtatattact attactcagt ttaattcttt cactaatttc
    57361 tctattggga agtttgtatt tttgatatca acaattttgt ggatttgggt tctatttaga
    57421 gtaaatatca tttttgtttg gtgattaagg agtttattaa aattaatttt ccctacttca
    57481 aatgcaaggt aacaagatat agcactttta ggaggaatat ttagcggtac agcttcagag
    57541 tatattctat tatcatcgac tgatcctcct ttagcaatta atttcttaaa tggagtagct
    57601 gaccatctgc ggtttaagtt agcggatgaa agttctaaat taactaacat agctggttct
    57661 gttgaatagt tagaaatgat tacttttgta taaatcatat ctgcagcgaa gtaagaagca
    57721 ttaagttcaa cttctagttg agggcgcatt ccttttattt ttatccctgt taaaaacgta
    57781 ctcaatataa aacttattat tgacatccat tgaaaaattg ttaagtgaaa aaaattcaaa
    57841 ataaacacca ccagttttta actaaattat accaaaaagg agagaagaaa taatgcaaga
    57901 attagtaatt ttgaaaaata aagaagctgt gactacgagc ttacaagtgg cagaaagctt
    57961 cgagaaaaaa catcaacatg ttttaagaga tattgatgca ctaaaaaaag atgtgtccaa
    58021 ttttggacag atgtttgtag aaggtaatga accagattca tatggcagaa atcgacgagt
    58081 tttcttcatt agtagagatg gatttttctt gctggctatg gggtttacag gaaagaaagc
    58141 tatctacttc aaacaaaaat acattgaagc attcaacgaa atggaagatg ttattcgcaa
    58201 gaatactgtt cctcaaacaa ttgaagatat gatgatctat caattagaag aaatgaaaga
    58261 tgttaaaaaa gatgtttcca tgcttaaaga tactatgcga attagcggac aacaagagtt
    58321 tgaaattaag caaaaaggaa atatgaaagt tatgggagtt ctagggggaa aagaaagccg
    58381 agcttatgaa gaaatcagca aaaaagtatt ctcaaaattt tggtctgaat ttaaacgtac
    58441 cttttcaatc ccaagatatg gcgagttacc tcgtaagaga ttcgatgatg ctgtttcatt
    58501 tattgaaatg tggttgccag aaactgcgat ccgtatggaa attgatcaac tgaacagaca
    58561 acagagactt tttggtgatg acaatgaata gagctgaagc gctaagaata gggacggcaa
    58621 ttgctaattg ctggtggaaa tactataaac caatcatcct aagccaacaa catattgaca
    58681 agcaaaaagc atggcaacaa ataaaaaagt gactccgccg gcaagcaaag agtcacaaag
    58741 aaaacacatc ataaggagat tttagcatat ggaaaaagaa ctttccactc tagatcaata
    58801 tttgattgat cctgattggg gcaagccgaa aattgaggaa acaagtggtc gaaaaatcag
    58861 acgaaatctt ttgacgaatg aagaactagc ttgggatcaa gatgatttag gcaaccatgt
    58921 aactatttgg gatcatgttt atcttatcca tctatcgaag cattcgaata aacctgaata
    58981 tatttacgtc atcgaagatg gcttgattga tgcgctagaa gagtacgaca gagataactt
    59041 gattgatatc tcttattacg gaccaggtaa gaaatacatt gctgaaatgg aggcagaatt
    59101 tgatgagtga aatcaaaggg acaacgaact ttgaaaaact ttttagtcgt aagttaaata
    59161 aaattctcaa gaaaaaagga aattttgatt atttatcttg ggctcacgcg tgggagatta
    59221 tgaaaaagaa tgatccacag gcaacggtaa ctattaatga gtacaaacac tacagggttg
    59281 tttctggaac tcatcaagac tttcttgttg aggaatataa accttttctt atggatgaaa
    59341 ctgggactta tgtatctgtc tcagtaacgg ttaaaggaca cacggaaacc gaattatttc
    59401 ctgttttaga ttatcgaaac caaccagttg ttaaaccaaa tgcaatgcaa atcaataact
    59461 cattgaagcg atgctttgtg aaagcattgg ctctacacgg actgggatta tatgtatttc
    59521 aaggggaaga tattccaaca ccacctagaa tcgatacaaa gaaattaaac atgctagaga
    59581 cgattctaga agctttcaat gagcagatgg gtaaagatat gaccaaaacc ttaatcgaat
    59641 atgttaatga gcagacagat aaattagggc tcttagctga taacgttgaa actattgaac
    59701 agttaagcta tgagcaatgt gccttgatgg agcgagcaat agcagctaag agaaaagaat
    59761 tagataagaa gtgatatgag tgtttaaacc attaatcgat tcatattcag cggttctgaa
    59821 aaagttcaaa ggaaaagaca taagcgcaac catcaatgag gaagtgaaca ttgatcgact
    59881 aaagacgatg tatgacggct acgatggtga tcgagtcatt gaaattcgtt ttattgatcc
    59941 tagacgtttc accgtacagc aacgaaactt catctatgcg ctgataggcg atatttttat
    60001 cgatacaggc atgccaacgg acttctggaa ggaattcttc tactttcgtt ttgaaggtgt
    60061 cacagggcgc aaaataagcc tgaaagacga atcgaataca actgtgagtg atgccaatgt
    60121 cttagcaaat atcatcttag atttcatctt tgaacatcat attcctttca aagaaggcta
    60181 tgagatttta cctgcgaatc aagaatatta cttctacaaa tgcatcacaa aaagagtctg
    60241 ctgcatctgt ggcaaaacag gagctgacat cgatcacttt gacaaagcgc taggaagacg
    60301 aaagcgcaaa gaagttgatc atgcagagta cacatttgca gcactctgca gaatccatca
    60361 cacagagaag cacaaaatag gtgtgattaa tttcaaaaat aaatatcaaa tcaaagggat
    60421 caaattaaac cagaaaacaa tcaaaaagtt aaatattgga gggtaaaaat gacagaacat
    60481 cgaagttatt atgcgattat accagccaac gtaaggtacg acaaaagact taaaccaaat
    60541 actaagttgt tatacggaga gataacggcc ttgtgtaatg aaagaggctt ttgttgggca
    60601 ggcaatgagt actttgcaga tttatatggt gtgaataaag agaccatatc gcgatgggta
    60661 agtgatttga ttaagtttgg atacttgaat cgggaaatca tttacaaaga gggtaccaat
    60721 caaataatca ataggtacct acgaattaat caatacccta ttgacgaaaa acgcaatacc
    60781 cctattgacg aaaaagtcaa agataataat acatctatta ataatacatt taataataca
    60841 aaagaatata taagagagtt accgccttcg aaaaaatcga aggctaagcc cgtccgtcat
    60901 aaatacggag agtataaaaa tgttcttttg tcagatgagc agatggagaa actcaaaaca
    60961 gaattcccta atgattacca agagcgaatc gaacgactgt cagagtattg tgaatcatct
    61021 ggtaagactt ataaaaacta tttggcaact attcgaagtt gggcaaggaa agaaaaaagt
    61081 gaacctaaga acgcaagcag tggatacaag cgcacaggaa gacgagagaa gcttcctgaa
    61141 tgggcaatcg accaagaagc ctatctcaag aaaaaagcgc tagaacgagc taatagacaa
    61201 tcaaaagcac cattctaaga ggtggaaaaa tgaagatcga ttatctagaa ctaattaatg
    61261 aaatagcgaa ttataaaaag ggcgaggaat tagacgtcct gagagacgta tatgatcaac
    61321 tcgaagaagc tggaattgaa ggaattaaga atgatcgttc gagttggagt aaactcagat
    61381 actatttcgc actctatatc gatggaacgc aattaagaaa tttagcatat accaaattac
    61441 tattcattga ttgtgttaaa ggcttgcaaa aacatcttaa tgaacttgag caggtgtaaa
    61501 caagatggac ctaaagacat ttacagcaca gatcgaatta atgcatcaag aagctttaag
    61561 acaaagtgtg tcgtacgaag acaagtggct caacacattt catggcggac gtgagagcgc
    61621 acttgatcaa gtactcaaat tactgaaagg agaatgtcgg gatggataag aaagcggcaa
    61681 tgcagcgaat tatcgaattg acttattcag aagattggca ggaagataaa aaaatagttg
    61741 cagaagtcca aaagctcggt aaatcaatgt ggactgaaaa gcccaaacgg agaacgccga
    61801 gaaagattgc aatctggcat ggtgatcgaa ttctagtaac gggtaccgct aaacagttat
    61861 ctgaaattac tggtctgagc aaaaatatta tttgggatag agctaggagc ttatggattg
    61921 attcaaaagg aagacagttt aggtatgtgg aggagaaata atggacgaac taatcgcgaa
    61981 agtagagcag tgggcaaaag ataagggatt ggatcaagcg gatttcagca agcaaatgtt
    62041 aaaaacggtc gaagaaatcg gggaagttgc cgcttctcta gctagaaaag atgaacatgg
    62101 tttaagagac ggaattggcg atgtagtagt aaccttgatc atcttggcaa tgcaaaatga
    62161 tatggattta tacgagtgct tggattttgc ttatgacgaa atcaaaggtc ggactggaaa
    62221 gatggtcaat ggtgttttcg ttaagtccag tgacctgaaa taattccatt aatggaagaa
    62281 ataactgaat aggaggatag acatgattga tgcaaaacaa gtgcaaaaac agaaagatgg
    62341 aatgttgatg tttgaagcat atgttctacc atttcttaat caatttgaag ttttggaatg
    62401 ctctgccagc ggagaagaat tggagtatgt tgtaattcgt gaaaccaaag aaaacgttca
    62461 gaagctaaac gaatttcttt gcactattaa ctgttgggat atgatagctc caggattttt
    62521 atgtccagct atgggagaat ttttggaata ttgtcgtctt gaagatgcag gcactttgga
    62581 tttagcttat ctggtataca actacctaaa catcaacaca gatcatttgt ggtttggcac
    62641 tgccgaaaga aaatgggtag tccgctaacc accaatatca atgaaaaaag gcggtttcct
    62701 gaaagtggaa ttgccgccat tgctgtaagg ttctttacgc gactcaaggt cacagaaata
    62761 taaatgcaaa tctcttttga agtgatccaa agctctcgga aaatggaagt tttttgtttc
    62821 aaagaataaa tgagatttgc gtcaagaacc tgagagttat ttccaaaaaa gcttccaaag
    62881 aaccgaatga gctaaggaca tcatgtgtaa acacataata tagctctcct ttcacggcta
    62941 atcataacat gaaaaatatt cgatgtcagt aggaaaaaag gtgaattatg aaaagaatat
    63001 taaattatcc cggcagtaac agattctgca attaaactcc gaagctgatg tatcagtatc
    63061 aactgtagaa tattatgagc gtggagaaag tcaagcagtc acaaatgtaa aaatcgataa
    63121 cgtcaacggt cttatctgtt tagatgaagg cgatagtatg aatgaaattg ctgcagacca
    63181 tgaattatca gaaactgctt taattgatca aatcgaatta gctagacaat actttgttcc
    63241 atatgcagat acctggtcca agcataagaa tgacatcatt tttccagagg aacaatgaga
    63301 gcaactgatc cagtaattat ccttgaggaa gccaaattta tttggactca cgaagagata
    63361 gagcaagcac gcttgctctt ttctcaagga gttaagccga gcaaagtagc tgaaataatg
    63421 ggtcaaaaga ttcttgatgt cggattgctt ttgctccatc tagcagaaaa aaatttgatt
    63481 tgaggtgaaa atgatgattc aacttgcagg catccaaaca gggaaaattt atttttctgg
    63541 agaaagcaaa agcgaagcca accaatggct attgaaaact tacacgaaca ataagaagct
    63601 aaggaaaaaa tatcctgatt tgttgctaaa ggatgatcag attatgccgg aaccgatgat
    63661 tttgacccgt aaggagggaa gttgaaacta aaaaaccagc cgtgtgggct ggagttgcta
    63721 tttcttttta ataatgagtt tttctaaatt taattcattc tcacgagttt gcgtccaata
    63781 atcagaataa tattttaatt gtttaagagt aggaatgtcg tcttcggtaa aattagaaaa
    63841 taattctgga gaattatctt tttttaattg ttctaatcct gattctttaa aacgttgttc
    63901 aacgagtttt actaaattgt tgatattcat gataaatcac ctttttaaat ttaatttcga
    63961 tttgattaat cgatacaagt attatatcaa ataaaaaagc tgatttaggg ggtcttacaa
    64021 aaacactaaa attttttcaa aaagaggagg aacggtggtg aaagtcagag aacaattcaa
    64081 gatagtgagc gacgaagata atgtttacaa aataaagatc gttaatatta atgaatatcg
    64141 agaagcagat cacaaatatt tggttgactt atacatgaac gataaatatt tgggagaagg
    64201 attttgtgga gattcacttt ttgatgatga gcgaattttg aaggaggaaa cagaatgatc
    64261 cacgaactaa aaatactacc agaatatttt gaagcagtga cgagcggacg caaacaattc
    64321 gagatccgca agaatgatcg tgacttcaaa gttggtgatc agttaatact acgtgaatat
    64381 aaaaaataca ttaaacatga attacctgga ctaacgagac caacatttag ttacactggt
    64441 gactcataca aagcagagat cacttatatt actgattaca tgcagaagtc cggatatgta
    64501 gtgttgggga ttaaaggggt gaattaaatg aaagtataca tcttagctat cacagagggc
    64561 acatggatgt tcccagtcgg ttccggaaaa atctataaat caaaaacagc tgcttataaa
    64621 gcatttgaaa aatacaaaaa agaaaacggt ggcggcacta acgcaaagat tctagtggct
    64681 gataactggc atgaagaagg tgaacgtaat tgatttacct gttcattttc gtggtactaa
    64741 ctatttttat gctagtaatc ttattcaaaa aaagatgagt aaagacgaac gaaaaattct
    64801 ggccaacttt tatttagtat taaaaatcga acaaaatgtg ttttcggaaa ggagaattgt
    64861 atgggaaaaa caaaatcaaa gattaagaag aaaaaacgac gtttggaaca aaaggcaatc
    64921 cagaatggaa cggctaagaa aaaataaaaa agctacccct ttcgagatag cagcgcaata
    64981 ctattctacc ataaggggtg gcgtttgtga gatttcattg gttaaaagat taccaagaac
    65041 tagatgagca gattctttac ttaaagtgga atcttaataa aagtaagctt gaattgaatc
    65101 gatgggtctg tggtgattta gcaaacgtcc gcatcgaaaa gaattcgaga acttcttctt
    65161 tagaagagaa tatccaaaag atagaaaatg aattggaatt gttgatcgag caaaaagaag
    65221 aaatgttatt gctgatagat agcttttctg gtatcgataa tcaaattgtt aagatgaaat
    65281 atgttgatca aatgagctta gaagatattg ctgaatctgt tgggtatagc tcatcgtatg
    65341 tcagacagcg acatgcagaa attagaaaga cattgaactt tttagatgag tatgaacaca
    65401 gacaagctga ccgattgaaa aaagaaaacg aaattgattt ttacaatagc gagaagtaca
    65461 aagaacaact ctctttattc taaaattaca ctgttcacta aatgttcggt cattgtagct
    65521 atgtaaacat tgttagcagc atgatattct attagtgtca aaaaaatatg aaagagccaa
    65581 gatatcccaa ccgttttatt aattggtatc tgtggctctt ttattctttt aattagtagt
    65641 tggcataaag ttatttccat ttataaattg atcagctaaa tcagcatcat aatcagccgc
    65701 gataaattgc gctgctgatt taataaatgc atccatatca tgaacatctt tattagtatg
    65761 tctacgaaca tagtgcgttt catcattacc aatccaagta gcagctttgg ctaatctttg
    65821 gagtttagga aaatcattca aataattttc aattgtttta cctaataaca ttttttttat
    65881 tttatcttca tcctctgaat ttttagatat tgcataatct ttaattagaa attctagagc
    65941 ttttctataa ccaactccag caatttgttc caattgctca gatttagctt gtgtggcttg
    66001 agtataaata tcaacaaatg taggagaaac tttttcaata ttttctggta aatctatttt
    66061 aatcggcgga cggtaataat ctttaattaa aatattttca gaatatcctt catcttcatt
    66121 aaacgtattt ataaattgta aactataaaa tttgttgcac tcatcattta tacactgtac
    66181 taatacgcca aagattctat cattatcgaa cgcactatat gatgaaaccc caaaatacac
    66241 atacggagtc attatatttc cgcaatgcgg acaactattt ggcaaataaa ttgtctctgt
    66301 attttgacga tcacgatact taatattaac ttcttgaagc attaaaacac ctcgcatctt
    66361 ttttataaat cataccacaa aatatctgat aggagagtaa acaaatgaat gattttcatg
    66421 aagcggtact tagtattgaa gtagaatcaa gtttggctaa agtttataag aaagcaattg
    66481 aagcagagaa tagtccgtac agagaaaatt ggaatggtaa tcatgcacat gtgcaagtgg
    66541 agaatgatga ttacagaact ggaatgaata cgttagttat ttctttattg tcacacactc
    66601 tacccaatct gcaggaaacg attgaatggt atgagcgaat gggcgcaaaa gtaatccgta
    66661 caaattacaa aggagagaat taaaatggca atgatcaaaa ttagaacatc cattagtgga
    66721 acagagtatt gggattcaga aaagaaaagg acagtagttg ttccgaaaga tcaagaacca
    66781 aattttgaag taaaagaaga aaaaggaatt ttgagtgatg gcaaatcatt tgttgctgtc
    66841 aatggcgaac tcatagctca tagcagtgaa attcttgata gcgatggaaa cactgctgct
    66901 aattttgatg gagacgaagc tactaatgat cagtccactg aagatacgga tgaactggac
    66961 aatatgactg caaaagaatt gcgtgcatat gctaagaaac atggtattga tattcctggt
    67021 gctatccgtg caaaaggcga tatcataaat cttattcgtg aagtagaatg aaatactgtc
    67081 agtttgacgg atgcacgaac aaaatagcaa agggtatcta ctgtactgaa cacaagagat
    67141 caagcagatc acgcaagaag aagcagcaag caaagtctgt ttatcatcat gagaacaaac
    67201 cattctatcg aacgcaagca tggaaagata tgcgtcaatt tatttatgaa agagaaggtg
    67261 gtcattgtca gcggtgtggt cagttcatat ttggaaagag agcacacgtc catcacattg
    67321 taccaatcaa agacaacgaa ctgcttaagc ttgatccaaa caatctcatg ctattatgtt
    67381 caaaatgtca tccaattgtt gaaaacgaaa cggaagacaa aaaagttttt ccttcgtatt
    67441 tcaattgaag cccccctatt cattttcaaa attttttcgc gtggggagat agggtagcgg
    67501 ggagtcacgc gcatcgttag gtcaaatttt tcaaaaaaca aaggggggtg tatacaaaaa
    67561 tgacgactaa agcgcaacgt aaagcgatta ttgatgaaaa agtaagtgct gaaaaagctc
    67621 gtatcttaga aataatgaat ttgtctgatt tgtacaccat cactcttgat ccattaatcg
    67681 aatcatactt ggatattttt gaaatttacc aacacaaata tttattgtgg aaggaaaaag
    67741 gatttccgga gacgcaaaaa ttcacgaata aatcaggagc tactaatcaa tcaaaacatc
    67801 cattggcaca acaagtagaa acttgggcag ataagaagat gaaagctcta gatttattag
    67861 gattaacaaa caaagcaaaa actggtagac taattgctgg aggatcgacc gcaagaaaag
    67921 atgaagaaat tacacgccca gaagtaaagc cagtagatga actagcagcg cacagaaata
    67981 aatggcgtaa gaaggcaggt gctgaaaaat gattgaacct ggtgtaaatt atgctgattt
    68041 atttgcaaaa gaagtaagaa agaaacctaa gaagtatcct aagaccgttc gtttagcaat
    68101 agatcgctgg tatcagtgga aaaaaagaaa agatatttgg tttgatgtag atcgcgcgaa
    68161 tgaaatgatg gattgggtag aatcatttat tgttcacaca aaaggagaaa tggtgggaaa
    68221 accgtttctt ttagaaccct gggaaaaatt tatttattct tggatttatg gttgggttaa
    68281 agaaaatgaa aaaggccaaa ttgtacgcgt tactcgtgag gcttatgtcc agattccaaa
    68341 aaagaatggt aaaacattga ttgctgtcgg ttcattagga tatgcaatgt acggagaagg
    68401 ggcgttatca gttgattgct atgcttgcgc atctgatttt gctcaagcgc aatatgctgc
    68461 caaacctttt gcagttacaa tcttaaacaa tccaatccta cttgaaggaa ctaaaatatt
    68521 tagggggcca aagggaactg tttctagtat tacttatgac tatattcatg aagatatggc
    68581 ttactcaaat aaatttattg ttcaaaccaa gaatattgat aatatcgagg gatccaatcc
    68641 atattttgta ttgaacgatg aattgcataa acaggagaaa atggaacagt atgacaattt
    68701 taagtctgct cagatatctt taccacagcc attgatgttt aatatctcaa ctgctgggaa
    68761 aggttcgtcg tctgttggaa tgcgtgtata tcgcgaagca aaagaagtgt tgaaacgtga
    68821 tgataatgat tcaaactttg ttctaatcta tgagccaaat aaaaattatg attggacgga
    68881 tagaaaagtc tgggaaatgt gcaatcctaa ctggggaata tcagtcgatt tatctgcttt
    68941 agaatcggca tttaaaacag cgcaacggtc agctcattcc aaagctgaat ttctaacgaa
    69001 acacttggat gtatttgtga acggcgcgga taatttcttt gaacaggatc aagtagagcc
    69061 atgtttagtt accacacaag aacttggtga tttaagtggc gaaccatgtt atatcggttt
    69121 agatttatca cgtacacgag atttgacctg tgtatcttta aacttcccaa catgggatga
    69181 agatggtaaa gcggttctta aagtaaagca actttatttt attccgaatg aagatttaga
    69241 gtttcgagaa aaagaagata atgttcctta cagtgatttg gctgaacaag gtttcgttga
    69301 attttgcgac ggaaaaatga ttgatcaaga tcagattttg cagtacatag aggactgcat
    69361 gaatttatat gatattcagc aagtgaatta tgatccagcg atgagtgaca aacttgttga
    69421 gaaattagaa aacttaggat tggaatgcgt tgaagttgct caatatccta aagtattgaa
    69481 tgctcctttt gacgatgtcg aacggttgtt ttatgagaaa cgaattcaat ttgataatcc
    69541 attattcctt tattgcactt tgaacgttgt agcaattact aacatcaatg gacaaaaagc
    69601 gccaagtaaa cgtcaatcaa agaaaaagat tgatgggttc gtggcgtttt tgtgtggtca
    69661 taaggaaacg atgaatcaaa tgacagatat tgattcagat gagttagatg attacctaag
    69721 ttccatctat agataaatag aaaggcggtg aaaaaaattg aaattacgtg atcggttatc
    69781 gaatgcagtc tattctttta tggaaaaacg tggatatatc gaggatattt ttggacacta
    69841 cacacgttat ggtcaaagat atgtgacgga ttcatctatc atggaatctt ctgatgttta
    69901 tgaattagtt caagacatat ctaatcaggt ggcattggcc acaccaattg ttattggtcc
    69961 cgacggcaac gaagtcaaag atcatcactt actaaatatt ttgaagagtc ccaatgatta
    70021 tttgacagga ttcgaattta ccaaattgga aacaaatact ttattgatca atggtgagac
    70081 attcccatta acggataggg atcagcttca tttggcgtac ggtgtaacaa ctaaaatcaa
    70141 tgaacgactt caagaagaat ttgaaatgaa tggtcaaaaa atacctggtc aaatgattcg
    70201 acacattaag aacatcggaa ctgattcatt aaaaggtgct ggaataattg atcttgcaag
    70261 aaacactcta gaaggcgttc tgagcgctga aaaagttttg acggacaaat atactaaagg
    70321 cggtttactt gcgttcatgc ttaaactaga cgcccacatc aatccaaata atagcgccca
    70381 aacaaaaatt gtcaaagcta tattggatca actggaagga acgcaaaatg agagtgatca
    70441 ttctgttaag atgattcctt tgggaaaagg atattccatc gagacattaa aaagtcctgt
    70501 tgatgacgcg gcaattttga attatttagg tgtttacaaa aaagacttag gaaaatttct
    70561 aggaatcaat gttgatacgt atcaatcgct gatgaagaca gatattgaaa aagcgatgat
    70621 gtatctgcac aacaaagcaa tcaaaccaat attgaaaaac aagagcgaac attacaccgc
    70681 tctttttttt atgcctaatt ctggctatag agtggaatgg aaaattaata ttttggattt
    70741 tgttccttac tcaacaaaaa caaatattgg ctacaacatc gttcgtaccg ggattacaag
    70801 tccagataac gtggcagaaa tgcttggttt tcctaaacag aatactccag aaacacaagc
    70861 tatctatatt tcaaatgact tatctaggat tggccagaaa aatgcaacag atgattcctt
    70921 accaacgaat gatcaagact tgaaaggagg tgatggaaat gaagaagaag gaaattcgca
    70981 cgattgacat caccaatctt tcaacacgtt ccgatgaaga aactcatacg aggaccatta
    71041 gcggctacgc tgctgtattc aacagtcaaa cacttttatg ggatgactta agcgaagtga
    71101 ttgttcctgg tgcattctca aaggcaatta gtaattcgga tgttcgttgt ttgttcaatc
    71161 acgattggtc caatgtgcta ggacgtacta aaagcggaac ccttcgcctt gaagaagatg
    71221 aacgtggttt gaaattcgaa gttgatttac cggacacaac ggtagcaagg gacttagtta
    71281 aatctatgga acgaggagac atcaaccaat gtagttttgg ttttgtgccg actgaagaaa
    71341 cgtgggacta caattctgaa ccaatgcttc gaacaatcca tgaagtggaa ttatacgagg
    71401 tttctattgt gcctttgcca gcatacgaag atacagaagc tgcattaaga agtcgtgatg
    71461 aattagaaaa aaacgtcgaa gaaagaaaaa aattaatcaa aaaaattaat caagcgctag
    71521 aagcgtagga ggaaaaatac atggataaag aattattgaa aaaaatgaag gcacgtcgtg
    71581 agcaacgatt gactgaatta cgtgaaaaag ttgaatcagg agaattacgc gaagcagatt
    71641 tagaagccgt gaaagaagaa attgacagtg ttattgatga attgaacgga attaaagacg
    71701 aattaggcgc agattctgga actgatgaaa cagacgacaa tacagatgat caatcgaata
    71761 gtacggattc agacgaaagc cgttctggtg aagacaacga tcaagaagaa gattcagaca
    71821 gtgaagatag ttcagaaaat cgttctggaa tgattactca acagcaacga gatggattac
    71881 ttggatcaat taagaacgga ttggaggcac gtgcaaaaat gaccaagaaa caaaaagatc
    71941 aacaactacg aaaagcattt gctaattttg tagctggaaa tatttctgaa gcagaagctc
    72001 gagctttagg gattgaagct ggcaacggtt cagttactgt cccagaagta attgcatctg
    72061 aagttattac ttatgctcaa gaagaaaatt tacttcgtaa atacggaaca gtggtgcgaa
    72121 catcaggaga tgtcaaatat ccaattcttg tgaagaaagc agatgcgaat gtaaacaaga
    72181 aagagcgttc aactgatatt gctgaaacag ctattcagtt tgatgaaatt ttgcttaatc
    72241 ctgccgaatt cgatgctttg gcaacagtaa ctaaaaaatt attaaaaatg tctggtgttc
    72301 cagttgaaga tattgttgtg gaagaattga aaaaagctta tgtgcgtaaa gaaatcaatt
    72361 atatgttcaa tggtgatgac gctggaaatg aaaatcctgg tgcattagcc aaaaaggctg
    72421 tagcatttaa aaaaccttta gatctaactg cttcaggtgc tgggcaaaaa ttatatgatg
    72481 cattaatcga atttaaaaat acaccagtga cagaagtgat gaaaaaggga cgctttatta
    72541 ttaatcgagc tgctttgact gccattgaaa aaatgaaaac agatgatgga tttcctttgt
    72601 tgcggccatt cacacaagca gaaggtggaa ttggttacca attagttggc tatcctgtgg
    72661 attggacaga tgcagcagat aaaaagggtg aaccagacac gccagtttta tattttggcg
    72721 atttttctgc atttaaaatt caagaagtta ttggtgcctt ggaaattcaa aaacttgttg
    72781 aaaaattctc tggtaaaaat caaattggat tccaaattta caacttgcta gatggtcaat
    72841 tggtttattc tccatttgaa ccggcagtat atcgctacga aattacaaaa ccagttggtg
    72901 gttaagatgg aagagcaaac taaagaattg tctttagagg aaaaattcaa atcacatatt
    72961 cattttgaag agggcatgga tgattctttg ctctcttttt atttaaatat ggcaaaagat
    73021 tatgtcaaaa cagcaactgg tggccaacaa gaatatctta ttttgatggt tgccggcatt
    73081 gcctatgaat atagagtttc agaggatgaa ctcgacaaag ctatgaatgc catgacgcca
    73141 tttatcgtgc aaggagcgat tcaaaatgcc gaagagacag accaataatc tcagatggaa
    73201 agccgaattg ctagacatca aaacaggaac agacggaaac gatcgtccaa ctacaattta
    73261 cgaatttaag cgtctaatat tctatgaaga actcggtgtg acttctcaag aaaaatattt
    73321 atcacagcaa gccaagacag acgttgtcag acgaattaaa gtcagatggg ataaatccat
    73381 cacagagaaa ttaagtgcgc tcaaaattga ttctgtaacg tataacatta ctcgcattta
    73441 tacgaatccc gatgcaagag aaatggagtt gagtttagct tatgtcgatt agctttgatg
    73501 aattgaaaac agcgctgaaa tcaacaaagt tagcagtgtt cagagacaaa gccagattag
    73561 ggacgatgta tccatacatt gtgtactcaa atgtgagtaa cagcaaaaaa atggcatccg
    73621 gtaaagtcta taaaaaatta ccttattacc aagtctcttt ttttacactt ggaacagaac
    73681 aggatttagt tgttattgaa caagcgctgc aaaatgctgg cattccatat tcagatttta
    73741 caggtataca aggtgatgag aacgacgata ccgtaaccaa ctattacaca tatgtgaggt
    73801 gtgtggaaaa tgccaagtaa taagaatggt ttttctgaaa tatcggatta tttaggaaac
    73861 ctttcaaaag ttgatccgaa aaaattatcg ttggaatctt tagaagaagc agctaacttt
    73921 tatctaaagc agttgcttcc taatattcct aagtcgctct taaaaaagaa acatatgcgc
    73981 gatcaaataa aagtagtagt tgaaaacgat caagtgaaag ttcaatttga agagacggcc
    74041 ttttactggc gctttgccga aaatggcaca acaaatcaac gtgcccaaca ttttgcaagt
    74101 ggtacgtatg aacaaaacaa agaaaaaatt gaagaaatta tgactagaaa aatacttgat
    74161 ttatgggaag ggtgatttta attgggaaaa caagatactt tttattttga aggattggac
    74221 gacattttaa ttgcgatgat ggcaacgcca gattctgttg gaactgcacc gacttatagt
    74281 gaagttttac gattgccaat tgccacaaaa atcggtgtca aagggaatgg aacagcatta
    74341 gaaaaatggg catccagcaa aatgtttcgt cgtgtgtcgc gagaaacaaa acatgaactt
    74401 gcgttggatc acgtgggtat tccgatagaa gtgatggatg aaatcaaagg attagttgct
    74461 aaaagcggag taacgtttag caaaaatacc gcacgagaat ttccgtactt cgcctttgga
    74521 tttattggaa atattgaaaa tggcggtaaa aaagcagttt ggtatcctaa tacacaacta
    74581 tccaatgtga ttgacgaaga gtatgccact gcagaggaag aaacaaaaat tgacgatgta
    74641 actgcaaatc tggtttccat cggactgaaa tacaataatg tgatgtatgc aagttttgat
    74701 tcaaatagag acggagcttc tctagaatta tttaataaat tcattgctca acctgtatac
    74761 gatgaagaac agtggaaaac attggctaaa gttggaggtg cgggttaatg gctcggttat
    74821 ctgattatgg aattcacgtt gaagacttaa aaaattctgc tgttgtaatt attcaaggcg
    74881 cagaattccc tatttcattt actatgcaaa cgatggaatt tatagcagat gtgtatggtg
    74941 gagattattc gcaatttgaa tctgatatga acgccatgct atctaaaaaa gaaggacaaa
    75001 tttcttctgc taacttatcg cctagtgatc taaaaatcat gcgtgccttg atttatgcca
    75061 tgctgcgtac tggtggttta gaggaagatc cagaaactat tttcaaattt ttgggaatga
    75121 gtggagaggt gttgtctgct tatagtacct gtatggaaat ttttgctagc cagacatttc
    75181 aggtggaaga cctaaaaaaa tccaagaagc cacaagactt tcaaaaagcg caagcaaaaa
    75241 gaaagaaaaa caaaaagaat cggaagagat aggaactcct tggagttttt atatttacgt
    75301 tgctctcact ctattgaatt ggagtgagag tttcttttta aagtctacac ctaacttgtg
    75361 gctcaaatct tatttacagt ggttacaaca aaacaccgat tttgaaccac ctcaatctgt
    75421 aactatggat aaatcgcctt ggtggtagaa aggagcgcta agataaatgg ctggtaaaga
    75481 atctgatgtc gttcttaatt ttaaaacgaa tggcgaagtc agttattcga aaacaatcaa
    75541 agaaatcaac aaagaaatga acttagccgc tgccgagtac aaaaaccaag tgtctgcgat
    75601 ggacaaggat gcaactcaaa cagaaaaatt gcgagcggct aaacaaaaat tagaaaaaca
    75661 attaggattg gctgaacaac gatctcaaat gctgagagag gaatatgaaa aatctgtcaa
    75721 agaaaccggt gaatattctg ctgaatcaga aaaactttat aaacaattac tcaattctga
    75781 aaccggagaa aataaacttc gtacagcatt agaacagacg aacgatgcac ttaaagaaca
    75841 aggtgacgtt tctgttgata cagcaaaaaa actccagaaa atcgaagaaa caggtgagaa
    75901 agtaaaaggc gttggtgaaa aaatgtctgt tggagtaacc gcgcctattg tagcggcagg
    75961 agcagcagga cttgcagcat ttggtgaagt tgacgaggca cttgatacca tcattacaaa
    76021 aaccggagca acaggtgatc aagctgatag actttcacag tctttcaaaa acgttggttc
    76081 aaatactcat ttacctttac aaacggttgg ggaagctatt ggtgaggtaa atacacaatt
    76141 tggattcatg gataaaaaac tggaagattc aaccaattat ctcctacagt acgctgaaat
    76201 caatgataca gatgtttcgc aatcagcaat atctgctcga caagctattg atgcttatgg
    76261 actagaatat gatgatttga attctgtcct tgatgtaaca acgaaaacat cgcagaatac
    76321 tggtcaatct gtagacgact tgatgcaaaa agcaattgat ggcgcaccac aaattaaaca
    76381 attagggttg agctttggtg aaggggtcac tttacttgga caatttgagc aatctggtgt
    76441 tgattcaagc gcagctttaa gtagtttatc taaagcaaca gtggcttatg cgaaagacgg
    76501 aaaatcttta agtcaaggac tagaagaact acaagacaag gtaaaaaatg caggttctga
    76561 aacagaagcc atcaatgcag cagcagaagt attcgggact aaaggcggtc ctagaatggc
    76621 cgatgcaatt cgtagaggta ctttgaacct ggaagattta gcaaaaactg ctggagaaag
    76681 tgggggagct gtaggagaca cattcgatgc tactctcgac ccaattgatc aagccgatca
    76741 agctatgaac aatgcaaaat tagcaatggc tgacgtaggt gaagcagtcc aagtaagcct
    76801 tttgcctttt tttgaaaaag caacttcctt attacaggaa ttctctaaat ggtgggggtc
    76861 tctagatcaa gatacaaaga attggatcat aacaattgct ggtatagcgg cagcagttgg
    76921 accagtacta atcgttcttg gttcacttat gggatctgtt acaaaaatcg ttggggaagt
    76981 taaaagtttt ataggagttt ggcaaggact tgctggttta tttggaatgt cgggaggctg
    77041 gtttgcatta gcagttatag ctattggcgc attagttact ggactaattt gggcatataa
    77101 taacgttaaa tggtttcatg atggagtgaa ttctttcttc aaaggtgttt cagatgtagc
    77161 tgttgaaata tttaattttt taagtggtta ttttggtgga tttttcgatg gtgttatagc
    77221 aaatttcaat aatttttata atgctggaaa acgaattttc agtggttttc tagattttat
    77281 cactggagta tttacaggga attggtcaaa agcatggcaa ggtctagttg atatttttgg
    77341 aggtattttc gatggtattg ttgctgtagg gaaagctcct attaatgcca tgattggatt
    77401 gatcaatgga tttattggtg gattgaataa tataaagata ccaaaatggg ttcctggtgt
    77461 aggtggaaaa tcattttcta tttcaaaact gccttattta gcacaaggcg gtcatctaat
    77521 caatggacaa gcgattgttg gtgaagctgg acctgagtta ctgactgcca agaatggtaa
    77581 aaccacagtt actccattat cagacgaaga aaaacgcaaa gggatcagtg gaagagtttc
    77641 tggaggtagc attgaacagc atatacacat tggcaaagtc gatgcaaaca atccatctga
    77701 gttagatcgt atgaatcgta aatttgctaa agcaaacaaa caggctattc gtgatttggg
    77761 aggtgttcct atttgagtcg acaatttatg aatccagatg aaccaaattt tatttggaaa
    77821 aatcggaatg cagtaattga tatgaattgc atcattgagg cagagcttcc agatattatg
    77881 ccgaacaagc gatacgaaac ttacacgatt cagggccgaa gcggagaatt gacggagacg
    77941 tttgatgact atgaaccttt tgatttggaa atagaaggga tcactattcc acattcgaaa
    78001 ctgagagaag tcaaacgatg gctcactggt aaaagccaat taatcacaca taatgatcca
    78061 gacaagtatc tagaggctat ctgcagcatg gataaagaag tccctttcga aaacgagtgg
    78121 ggcttctttt atacattcga tgttactttt cgttgtcagc cactcaaaag aaaaatcggt
    78181 gaagcaccta aaatttttca ttctagtgtt atggatattt ttgatcatgg tgacgaaatt
    78241 gcacatccct atctggaaat agaatcgaac ggaggagata taacgatcgc tgtcggtgat
    78301 aaaagcctaa caatacttaa tacgttagct gcaacaatcg tggttgatac tcagcttgga
    78361 aaagcaatac aagaaggttt gaatttattt acgcgtggtg attggccagt attgcagcct
    78421 gaatggaatc aggtaaaaat atccggaaaa tttaaagaag tgcggttttg gaataggagt
    78481 gtgtatctgt gacgcaagaa tttatttatg cttataaaaa aatgccagat gatttgagcg
    78541 tgaacggagc gtcgttagtt gattgggaag atttgccaga aatcaatcgt gtgctgaatg
    78601 gccaatatcg tttttatggt aactattcaa gaagcggaca gtatcgctct tatttaaaaa
    78661 aaggaaattt tataaaagcg aaggtaccag atggatcatg gcaatatttt gaaatttata
    78721 atgtcaaaaa gaatttgacc tccgtttctg taacagctcg gcatattggt tttatggcca
    78781 ataagaactt tattgtcaag tcgtttacgg ataacggcaa tgggtctcag atcatgacca
    78841 atcttaaaaa cagtttggca tttgatcaaa aatttaacta tctttcgaat gtagggacaa
    78901 cgcaccaatt tacagcaaga caagtcgcgc cagttgaagc aatcattggt tcaaataacg
    78961 gtaatcaaaa tttgactggc gtgactagcg cggaacttga tatggataac tatgatttga
    79021 aactggtaaa acagattgga tcagataatg gttttcggat tgattttggc atcaatttag
    79081 aagcaatcga agaagaaatt gatgaagaat caattgtcaa tagtttgtat ttggttggcg
    79141 gtgttcctga taacgattat gatgaagaca aagaacctat cgaatatggt tatttagaaa
    79201 ttgatggagt aaccaacgag aatcgacgta ttgccaaacg tgaaaacgga gattgtaaaa
    79261 cagttgatga attgatcaaa tggggcaaaa ccttatttga caatgatcgt atccatgagc
    79321 caaaagctac tcatacagtc agtatggtgg cgttggaaca cacactcgaa tacggtgaca
    79381 tgtatcaaga gctagcgtct ttacactttg gtgatgtcgc tcatgttagg gcgaaagagc
    79441 tagatatcga gataaaagag cgtatggtcg aatacactta tttcccaacg cttgggaaat
    79501 ataaggatat tgttttaggt aatgatttat cactgtacac ttcggcagta aatactcaag
    79561 cacaagaatt gaaaaagaaa atcgacaatc gaacagaaac gttagttcaa aatgtgttga
    79621 atgcgacggc atggatcact ggtaattctg gtgggcatgt cgtttttcgt ccagaaaaag
    79681 ctccatcaga gattcttatc atggatactc caaatgtggc gaatgcaaag cgagtgtggc
    79741 gttggaattt aaatggctta ggttattcag acaacggagt aaatggcccg ttcggtattg
    79801 ctatcacatc aaaaggagaa attgttgctg acttcatcaa agtaggaaca ataaatgcag
    79861 aagtattcga aacttccttt aatgcttatg gtgatgtgtt aaaacttgta aaaggcacgc
    79921 ttcaaatttg gaatgaaaac aaaaaaatca tggagctaac caaaaaaggt atggaattct
    79981 ggaatagaaa agaatccatt ggaacgatcg gaacaacaga ttcagcagga aatccatttc
    80041 caaatgctgt aacacctaca cctcttgagg aaaattcttt ggtaatacgt acaaatggcg
    80101 atggaaaata cattttaatt tctccaactg cagaaaaagg atttgtgtta ttaggaaacg
    80161 gaaaagcata ttatttcggt gatttagata ttcagggaaa acttactgtt agaggtaaag
    80221 aagtgatacc aggacaaaat ggcggtccat ctggcggagg agaaacacct ggtgggtatc
    80281 ctgatgaatt aaaaacagat gcagaaaaga gagcttggag aatatacgat attttgtgta
    80341 ataacggatt tacgaaacaa tctgcatgtg gaatattggg gaacattcaa caagaaacag
    80401 gaggaacttt tgatcctgat actgttcaaa taggtggacc agcatacgga ttagttcagt
    80461 gggatggttc ttcatatcct cttgttggtc cagcaacatg ggatggaaaa gtttatgttc
    80521 aaaacttatt taatgctgca ggtattaaag aaccaataac gagcttagat gcacaagttc
    80581 gattgcttat ttggacattt acaaatggac aatggatggg cgtagtacaa cctacgacgg
    80641 ttgatggatt taaggcctgt actgatccaa gacaagcagc atatgctttt gaacgaaact
    80701 atgaacgtcc ggcagcgaca catcctgaac gtcaagatta tgcagttaac tggtataaca
    80761 aatttaaaga tttaaaacca ggaggagcta ctggagaagc aggactaaaa catttagagt
    80821 ctttgattgg acaacgaatt ggcaatggtc agtgttatgg cttgtctgca gaatattcag
    80881 gatatctggg tggttgtggc atgggtgctg gaacaaaata tggtttaact catgtgatag
    80941 gaaatacttc tgcagcatct gatattggta ttgcctatga ttggtctgct gttggttgga
    81001 aagtgattca aaaccctaga tatgatcaat tagtagttgg tgcaattatt aattgggcaa
    81061 gaggtggaca agtgggttca tggtttgcag acggaactta tggacatact ggcgttatcc
    81121 gaggcttagc taatggtcgt atgcaaactt atgaacaaaa cacagagtta ggtatgattt
    81181 gtggaaagtt agatcgccag tattatagtg caagtgcaat ttcttccatt gtcataccac
    81241 caaaataggg aggtgattta atggcaaagt ggaatgtcat attaagtaca acagaaccct
    81301 ataattacgt ggggatgatt caagttcgac aaggcaataa aaacactgaa gttatggaag
    81361 ctacaattgt cgaaaatggt cttccatatg atttatcaga atgtaaggta tattttgaat
    81421 cagttgttgg cggaaaatat ccagtccaat tagaaacaag aattgtggat gctaaaaaag
    81481 ggaaaatcaa atatattttt gataaatatt ccatgcagtg tttgcatcga caaacagcca
    81541 atttcattat atttaaagga gaagacttga ttggaacaac tcaagacttc tcctattttg
    81601 tcatcaatgc tgtttcaaaa acagaaggag aaatgggttc ttattggcaa tcaattgaag
    81661 atttaattgc tgatatgaca gattttatta atgaaaataa aggcgatttt acggactgga
    81721 tgaatgaaag gaaagaagaa tttgatcgct ggagagaaga acaggagaat agtttccaag
    81781 attggagaga aggacaagaa tcagattatt tgtcatggtt tgaatcaatc aaggatattt
    81841 tgaagtctat cgatccaggt ggagtaatgt tagccgaatt aatggatgca cgtgtagatc
    81901 ttcaaggtgt acgccatgaa tcgatttctg aacgtttcct atccgatcta aattatttgt
    81961 atcaaaaaat gaaagcagca cttttcacga ttgaatacgg tgaaattgaa gtgactgata
    82021 ttcttcaaga cgatctcttt tcagataatc acgaagtcga aaaaattgaa ac
//
LOCUS       DAFEEZ010000006        68683 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000006
VERSION     DAFEEZ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.006"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(592..1983)
                     /locus_tag="LP245_000491"
     CDS             complement(592..1983)
                     /locus_tag="LP245_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBL1518433.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2196..2582)
                     /locus_tag="LP245_000492"
     CDS             complement(2196..2582)
                     /locus_tag="LP245_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBL1518434.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(2638..3261)
                     /locus_tag="LP245_000493"
     CDS             complement(2638..3261)
                     /locus_tag="LP245_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBL1518435.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3325..3993)
                     /locus_tag="LP245_000494"
     CDS             complement(3325..3993)
                     /locus_tag="LP245_000494"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBL1518436.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4005..4445)
                     /locus_tag="LP245_000495"
     CDS             complement(4005..4445)
                     /locus_tag="LP245_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518437.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4504..5175)
                     /locus_tag="LP245_000496"
     CDS             complement(4504..5175)
                     /locus_tag="LP245_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL1518438.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            complement(5360..5758)
                     /locus_tag="LP245_000497"
     CDS             complement(5360..5758)
                     /locus_tag="LP245_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBL1518439.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(5755..6528)
                     /locus_tag="LP245_000498"
     CDS             complement(5755..6528)
                     /locus_tag="LP245_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBL1518440.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6525..7208)
                     /locus_tag="LP245_000499"
     CDS             complement(6525..7208)
                     /locus_tag="LP245_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBL1518441.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7375..8262)
                     /locus_tag="LP245_000500"
     CDS             complement(7375..8262)
                     /locus_tag="LP245_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1518442.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8259..9128)
                     /locus_tag="LP245_000501"
     CDS             complement(8259..9128)
                     /locus_tag="LP245_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1518443.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9265..10551)
                     /locus_tag="LP245_000502"
     CDS             complement(9265..10551)
                     /locus_tag="LP245_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1518444.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            10824..11402
                     /locus_tag="LP245_000503"
     CDS             10824..11402
                     /locus_tag="LP245_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL1518445.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            11402..12331
                     /locus_tag="LP245_000504"
     CDS             11402..12331
                     /locus_tag="LP245_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1518446.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            12328..14064
                     /locus_tag="LP245_000505"
     CDS             12328..14064
                     /locus_tag="LP245_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBL1518447.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(14127..14963)
                     /gene="pheA"
                     /locus_tag="LP245_000506"
     CDS             complement(14127..14963)
                     /gene="pheA"
                     /locus_tag="LP245_000506"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBL1518448.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(14960..15469)
                     /locus_tag="LP245_000507"
     CDS             complement(14960..15469)
                     /locus_tag="LP245_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBL1518449.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(15462..16757)
                     /gene="aroA"
                     /locus_tag="LP245_000508"
     CDS             complement(15462..16757)
                     /gene="aroA"
                     /locus_tag="LP245_000508"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBL1518450.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(16770..17861)
                     /locus_tag="LP245_000509"
     CDS             complement(16770..17861)
                     /locus_tag="LP245_000509"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBL1518451.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(17878..19044)
                     /gene="aroC"
                     /locus_tag="LP245_000510"
     CDS             complement(17878..19044)
                     /gene="aroC"
                     /locus_tag="LP245_000510"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBL1518452.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(19046..20110)
                     /gene="aroB"
                     /locus_tag="LP245_000511"
     CDS             complement(19046..20110)
                     /gene="aroB"
                     /locus_tag="LP245_000511"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBL1518453.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(20143..21165)
                     /gene="aroF"
                     /locus_tag="LP245_000512"
     CDS             complement(20143..21165)
                     /gene="aroF"
                     /locus_tag="LP245_000512"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBL1518454.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(21824..22798)
                     /locus_tag="LP245_000513"
     CDS             complement(21824..22798)
                     /locus_tag="LP245_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBL1518455.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(22779..24662)
                     /locus_tag="LP245_000514"
     CDS             complement(22779..24662)
                     /locus_tag="LP245_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBL1518456.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(24680..26905)
                     /locus_tag="LP245_000515"
     CDS             complement(24680..26905)
                     /locus_tag="LP245_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBL1518457.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            27020..28054
                     /locus_tag="LP245_000516"
     CDS             27020..28054
                     /locus_tag="LP245_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1518458.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(28121..29134)
                     /locus_tag="LP245_000517"
     CDS             complement(28121..29134)
                     /locus_tag="LP245_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1518459.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKHLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(29212..29400)
                     /locus_tag="LP245_000518"
     CDS             complement(29212..29400)
                     /locus_tag="LP245_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBL1518460.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(29840..29968)
                     /locus_tag="LP245_000519"
     CDS             complement(29840..29968)
                     /locus_tag="LP245_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBL1518461.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(29971..31344)
                     /gene="rlmD"
                     /locus_tag="LP245_000520"
     CDS             complement(29971..31344)
                     /gene="rlmD"
                     /locus_tag="LP245_000520"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBL1518462.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(31455..32510)
                     /locus_tag="LP245_000521"
     CDS             complement(31455..32510)
                     /locus_tag="LP245_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBL1518463.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(32520..33950)
                     /gene="gatB"
                     /locus_tag="LP245_000522"
     CDS             complement(32520..33950)
                     /gene="gatB"
                     /locus_tag="LP245_000522"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBL1518464.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(33947..35419)
                     /gene="gatA"
                     /locus_tag="LP245_000523"
     CDS             complement(33947..35419)
                     /gene="gatA"
                     /locus_tag="LP245_000523"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBL1518465.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(35419..35724)
                     /gene="gatC"
                     /locus_tag="LP245_000524"
     CDS             complement(35419..35724)
                     /gene="gatC"
                     /locus_tag="LP245_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBL1518466.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(35830..37866)
                     /gene="ligA"
                     /locus_tag="LP245_000525"
     CDS             complement(35830..37866)
                     /gene="ligA"
                     /locus_tag="LP245_000525"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBL1518467.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(37883..40117)
                     /gene="pcrA"
                     /locus_tag="LP245_000526"
     CDS             complement(37883..40117)
                     /gene="pcrA"
                     /locus_tag="LP245_000526"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBL1518468.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            40272..41831
                     /locus_tag="LP245_000527"
     CDS             40272..41831
                     /locus_tag="LP245_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBL1518469.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVVGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(41942..43873)
                     /locus_tag="LP245_000528"
     CDS             complement(41942..43873)
                     /locus_tag="LP245_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1518470.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(43891..44805)
                     /gene="pfkB"
                     /locus_tag="LP245_000529"
     CDS             complement(43891..44805)
                     /gene="pfkB"
                     /locus_tag="LP245_000529"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBL1518471.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSETETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(44802..45554)
                     /locus_tag="LP245_000530"
     CDS             complement(44802..45554)
                     /locus_tag="LP245_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL1518472.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(45713..45922)
                     /locus_tag="LP245_000531"
     CDS             complement(45713..45922)
                     /locus_tag="LP245_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518473.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(45933..47261)
                     /locus_tag="LP245_000532"
     CDS             complement(45933..47261)
                     /locus_tag="LP245_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518474.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            47397..47552
                     /locus_tag="LP245_000533"
     CDS             47397..47552
                     /locus_tag="LP245_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518475.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(47626..48213)
                     /locus_tag="LP245_000534"
     CDS             complement(47626..48213)
                     /locus_tag="LP245_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBL1518476.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(48296..49546)
                     /gene="clpX"
                     /locus_tag="LP245_000535"
     CDS             complement(48296..49546)
                     /gene="clpX"
                     /locus_tag="LP245_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBL1518477.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(49793..51082)
                     /locus_tag="LP245_000536"
     CDS             complement(49793..51082)
                     /locus_tag="LP245_000536"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBL1518478.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(51236..52168)
                     /locus_tag="LP245_000537"
     CDS             complement(51236..52168)
                     /locus_tag="LP245_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518479.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(52325..52984)
                     /locus_tag="LP245_000538"
     CDS             complement(52325..52984)
                     /locus_tag="LP245_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBL1518480.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(52987..54012)
                     /gene="sppA"
                     /locus_tag="LP245_000539"
     CDS             complement(52987..54012)
                     /gene="sppA"
                     /locus_tag="LP245_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBL1518481.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(54025..54315)
                     /locus_tag="LP245_000540"
     CDS             complement(54025..54315)
                     /locus_tag="LP245_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518482.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            54724..56529
                     /gene="glmS"
                     /locus_tag="LP245_000541"
     CDS             54724..56529
                     /gene="glmS"
                     /locus_tag="LP245_000541"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBL1518483.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(56601..57956)
                     /locus_tag="LP245_000542"
     CDS             complement(56601..57956)
                     /locus_tag="LP245_000542"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBL1518484.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(57980..59149)
                     /locus_tag="LP245_000543"
     CDS             complement(57980..59149)
                     /locus_tag="LP245_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518485.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(59146..60033)
                     /locus_tag="LP245_000544"
     CDS             complement(59146..60033)
                     /locus_tag="LP245_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBL1518486.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(60222..63914)
                     /gene="nifJ"
                     /locus_tag="LP245_000545"
     CDS             complement(60222..63914)
                     /gene="nifJ"
                     /locus_tag="LP245_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBL1518487.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNIGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            64113..64634
                     /locus_tag="LP245_000546"
     CDS             64113..64634
                     /locus_tag="LP245_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBL1518488.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(65333..65890)
                     /locus_tag="LP245_000547"
     CDS             complement(65333..65890)
                     /locus_tag="LP245_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518489.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(66069..66680)
                     /locus_tag="LP245_000548"
     CDS             complement(66069..66680)
                     /locus_tag="LP245_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518490.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(66793..67050)
                     /locus_tag="LP245_000549"
     CDS             complement(66793..67050)
                     /locus_tag="LP245_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518491.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(67647..67925)
                     /locus_tag="LP245_000550"
     CDS             complement(67647..67925)
                     /locus_tag="LP245_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518492.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKK"
     gene            complement(67959..68210)
                     /locus_tag="LP245_000551"
     CDS             complement(67959..68210)
                     /locus_tag="LP245_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518493.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT        19206 a        14834 c        12080 g        22563 t
ORIGIN      
        1 ctgttctaac attctcaact ttgtcagttt accataggaa aatgggaaaa tctacgaaag
       61 ctctcaacag aatcgtccta cttaaatacg cttttcttta ataataaata agttggttgt
      121 ttttgttatt tgcgctttca cttttcggaa taaataatgt gtatttatat ggaataaata
      181 aaaaaagagg tcgtgactaa aaacaagtca caacctctgg taaacggtgt tctcctgaca
      241 actcctcggt cacaagacac aatattcaac aaacatgaga agctattttt tgaaattgct
      301 ctttgtgact cagagtgaaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag
      361 cttgcatctg cggtaataag ctcaaccaaa cgtaaaatat gaggaactat ttttgtttgg
      421 ctgttcttat tacttgatgc agggcagctt tttcacaacc tcttattcac ggtgtttcag
      481 aagtagcttc tcggaaataa gccgaaattt cacaaaaatt tgagaaacta tttttaggaa
      541 acttcttctt atttcttaaa gctgaccact tctatcacaa cctctttttg actatgcatt
      601 cacatcgatc actttagaat catcattgat gacatcgcga tctaaatctt tgatgcgtgc
      661 acttgtcacg ataccagcta ccatgctacc gctgacgttt actgctgtac gtgccatatc
      721 gattaatggt tcaacagaga taactaaccc aacgattgct actggcaagt tcattgcccc
      781 taaaacgatc agtgaagcaa atgttgcgcc cccaccgact ccagctacac caaaagaact
      841 gattgttaca attgccacaa gcatcaaaat aaattccaaa ctaaagacat tcactccagc
      901 tgctggtgcg acgatcgttg ccaacatagc tggataaacg ccagcacagc cgttttgtcc
      961 aatagacaaa ccaaaacttg ctgagaaatt agctgttgca tcatctactc ctaaagcttt
     1021 tgtctgagtc tcgatattca atggcaaagc tccagcactt gaacgtgaag taaacgcaaa
     1081 gctcaatacc ggaaaggctt ttttgaaata gttgattgga ttgacttttg caccaatcaa
     1141 aatcagtgag tggacaatca aaacagcaag caatgctacg taagaagcaa cgacaaattt
     1201 acctaaattg acgatagctg caaaatcact tgttgccaaa acgtttgtca tcaaagcaaa
     1261 tactccataa ggtgtcaaac gcaaaacaag cgtcacgatc cgcataatga ttttatacag
     1321 actgtcgact aaatctgaaa agaatgctgc ttcttttggc gcttttcttt tcacgcctag
     1381 ataagcgatt ccgacaaatg ccgcgaaaat aacgactcca atcgtacttg ttgcacgact
     1441 acctgctaaa tcagcaaaaa cgtttttagg gataaaggat aaaatctgct gtggaatcga
     1501 taagttttca actgtttcct gacgtgttgc cagttcagag attcgtgctg tttctgcagc
     1561 tccttgtgtg aatttagctc cttggagtcc gaacagcatt gttgaaccaa ttccgatcaa
     1621 tgctgcaata gctgttgttc caagtaaaga agtcaataca gtcgcactaa ttttccctag
     1681 cttttcagaa actttcattt ttgtgaatgc accaatgatc gaaataaaca ctaaaggcat
     1741 aactagcatt tgcaagaatg atacatatcc ttgacctaca atcccgatcc attccattga
     1801 ttgagtaacg actttgtcgt ctacaccaaa gatcaattga agcagaccgc caaagacgat
     1861 accaactcct aatgctgtaa agacgcgtgt tgaaaatttt gtatggcgct tttgcatacg
     1921 atagaacaca tataataatg ccgcaaaaac tagaaccact aaaactgtga tgagtgttgt
     1981 catttttctc ctcctcatat tattaatgac aagtccatcg aaggaagtaa aggttcccga
     2041 gaatgattct tcaaccatcc tcctgaaaaa atttttttca gtgactttta tattttagac
     2101 gatttttatc gaaatgacat tctttttgct tacaattagt aataaaaaaa catacctgtg
     2161 atagctttaa tctatcgcag gtatgttttt actgtctatt cttgtttttc tgattgaaaa
     2221 ttcaatttta ccccaggctg atctaaggcg atctctgtca cctcataaga cattcggcgt
     2281 acgatatcga ataacggtgc tactagctcg tccacttctt cttgtgtgac atcattttga
     2341 ccttcaattt tccgattgag gatatgattg atctgactca cacttccaga taaaacatat
     2401 gtatcaaaca ctaaacggaa ctctaagcgt gctcctacga tgctatgttc tttcggatag
     2461 ttttcgatcg tttcttttaa aggcgagaag cctactttca aatctgtttc tacttcttgg
     2521 ttcggcaatc tcatatcata atgaaatgct tctacaactt ctttttgtct tctgatttcc
     2581 atataatttt atcactcctt tatgaaaatt ataacatatc tcctttgaaa ggggatacta
     2641 ctttttaatg atgctctgca aggtaaggat ttcattcaga tttcctacca cataatctgc
     2701 cgggatctca cccagaaaat gatcgatgtc gtaaagacaa gtagcgactc ctgcattttt
     2761 ccctgcttcg atatctaaac gacgatcgcc gatcatcatc gtgtctgttc tttctaaatg
     2821 aaaagtatcg atcaaataat ttaaagatgc tggatcaggt ttacgaggaa agtcctgatc
     2881 gatccctact acttcctcaa tcagatgtgc caatcgatgt tcttttaaca ggccccatgt
     2941 tgattctgtc aaacggtggg tcaggatgaa atgacgaccg ccgttgtctt ttagcatttc
     3001 cagtacttgt ttcgtttctg gaaatggacg ggaaacttcc gtactttctt tttcatatcg
     3061 gtgaaataat tcattaaact ctctggcatt caagtttgat tcattgatca aataactagt
     3121 agaatacttt ttcattttga agtagatttc ttttttgtcc atactgatac caaaatcttt
     3181 tagtgcttgc catgcaccat ctaccattgc gggatacgta tcaaacaatg taccatcaaa
     3241 gtcccatata taatttttca tgttcctttt gttccattcc tttgcttctt ttttctatct
     3301 ctcactttta gataaaggtg ttctttaaag tatttttttg tccagaattg tcaaatcatc
     3361 tgctaatgta tactggattg gttgtgcatt tgggatatcg atcgtatcca tttgatcttc
     3421 aggaacatct tctaaatatt ttgtcagtgc tcggatgcta ttaccatgac ccacaactag
     3481 taaatcttgc cgatctttta gttttggtgc tagatgatct tgccataagg gaatgatccg
     3541 attcactgtc atttccagac tttctccgta tgggatcaaa tgcggatcca agtgatcata
     3601 tctgcggtca aatctatttt ctgcggttaa cggcggaact tccgtatatc ctctgcgcca
     3661 tgtttttact tgatcttttc cgtatatttc tttcatctta tctttgtttt tacccacaag
     3721 atccccataa tgccgttcat ttagacgcca tgtttttatt ataggaagcc ataactgacc
     3781 catttcttct agtgcgactt gtccggtaag aatcgcacgt ttcaaaacag aggtataaac
     3841 ggcatcgaat tgaagtccgg cttcaagcat tttttgaccg gcaactgctg cttgttcttt
     3901 tcctttttct gttaaggcga catctagcca tcctgtccag taattttcaa aatttgcttc
     3961 gctttcgcca tgacgtaata atactaattt cattcttttc tcccttaaac attcgtttcg
     4021 aattttatac cacatgtttt gcatgtcaca cgtattcgtc cttttccttt aggtgcacgc
     4081 tgcttttgat gacaattcgg gcactcaaaa aaagtataac tttttcgatc cattttgact
     4141 tgctttttgt tttttatctg atgatatttt tctttgactc tatcaagata tttcaaataa
     4201 cgttgattct catttagtct ggggtagatt ttttttgata ggaaacgaaa tatcatccat
     4261 ccgaaaaaga cgatgaacaa caattgtccg attctatagg gcaaccaacg acttagcaaa
     4321 ctaaagacaa gcgcagcgat caatagaccg cgattcaact gatcaaattt cgcatatctt
     4381 ccctgcataa gtttgtgata gttctgctga aatcgtatta gcctttctaa ccatgtttgc
     4441 atcatattat ctcctccatc atctaatatt tattatgaca aaaaaatcca aaaagaaaaa
     4501 gccttaattg gccttttcca ttgcaacttg gtgaaggaca ttccgatttc tggtaaagtc
     4561 aatcacaatc actttctttt tatcttctct gttgactact cgaaatgtgt ccgtcaatgg
     4621 aagaaacagc ttcttagatg gtagctgttg catacgtata aaacgatgga tcatcgtaat
     4681 caattgagga aattgaatag acgtgtgaag cagacctgga tattttttca acagctgtgt
     4741 cgttttgatc agattccgtt ttttactgat cacttttaaa aagcttttta gaatcttttg
     4801 ctgacgtcta aaaatagaaa aagaattttc gtcatctatt tgataacgca tttgtttttg
     4861 cagttctgct gcagtcagat ggatcttccc atcgtttgta tcgatcatta aaccttctgg
     4921 aaacagttca accactgctc gatcccaaga ttcaagagaa agctcgatat aatcttttac
     4981 tggtaattcc aattctacct taaaaaagtg caaaacagcc gacagccctt ctgcttgata
     5041 gatttctcct aatgttagcc cctctagatg gaactctggt gaaaaatgca gcaatgtttt
     5101 attttcctgc aattgaacat atagaaatgt agatcgctca atcagagtat cttttaaaac
     5161 aactaaaaaa ttcatttttc tccccctttt ttcatcattt ttaaaatagc atattttgaa
     5221 aagaaagtct gatgcttaga gtagaatttc ataaaaattt actatttcat aagtattcac
     5281 gagaaaaata caaacaaaaa agcggaaata acgctcatcc gccttcttgt ttgtgtttat
     5341 ttcctcttca aacgcttgtc tatgattcag acttttctct atcgttattt tcatctaaaa
     5401 gttcttgcat tccgataatt tctcgatatt gatgaatctt agtgatacca atgactttgt
     5461 ctacatcaat actaaaacaa ataccattac ctggaatatc gatgttgatg ccttgaccaa
     5521 tcgcatccat tactttattc gtcaaactat cgggtactaa tgtcaacaca atatcttttt
     5581 ctggcgaaat gtccaaacct aaaaatttcc ctgaatcatg tacaccagaa cctcttccat
     5641 gtaagatcgt tccgcctgct gcacctgctt cttttgaaaa gtcgataaca tcttcgccca
     5701 ttcctccgtc aacgatcgtc acaatcatgt gaagattcaa tgctacaaga tctttcattt
     5761 gctttccccc aatttttgca atctttcttt ttcgattctg tctttttcat cttttcgttt
     5821 ataaatatat cctagtacta aagtggataa tattggtgtc aatgcaatca ttgcaaccac
     5881 accaaacccg tcaatgatcg gatctcttcc ttcaatttgt gcagcgattg ccacgctcat
     5941 tgataaaata aatgtcgaac acatcgggcc cgttgctact ccaccgttat caaaagccat
     6001 tgctaaaaag atcttgtcca cttttcgtcc taaaataaat gctagcccgt atcctgggat
     6061 caagaaataa taaagagaga atccgacgag caaacgccac atagacaatc ctactgctgc
     6121 gccgatccca attgaaatta ccatcagcat gattttcgat cggattctcc cctcgctcaa
     6181 ttcttcaacc tgtttgatca ttacatgaat cgccggctca gcaaacccta ctaagaaccc
     6241 cattaaaaag ccaaggggaa ccagtatata attgtaaggc aatcccgcaa tagcactgcc
     6301 taaatgctgt cctaccggta cataagccat attgactccg tgcaggaaaa ggatcaaccc
     6361 aatagtcgtt atcaagaaac ctttcataat gtcaaagaaa cgctttttgc gcatacgaaa
     6421 actaatgata ttcattaaaa caaataggat tacgataggt gccactgcca aaatgacttc
     6481 catggtaacg atttcgattc catctatcac ttgctgccag aaactcattg gaagatcacc
     6541 cccaaaatca tcacggcaag aatcggccct aacgaagcaa taccgaccat tccaaaactg
     6601 tcattttcat ttttcttttg tttgatcata ctagtcatcc ctccggcaag ggccaagata
     6661 aatggaacag ttactggacc agtagtcact ccccccgaat caaaagcaat cggcataaat
     6721 tcggaactgg tgaaaaatga ggcgatcaaa acgcctatgt agcctatagc catcaattga
     6781 taataggata gcttgaatac gacccgaagc agcgcaaagg ctagaaatac tccagtgccg
     6841 acgctgacga tcccaatcag caacactctg ccaatctctc cgtcagatat atcatatact
     6901 tgttgtccca aaacttgcac ggaaggttca gcaatcgtga tcacgatccc gatagcaaat
     6961 cccaaactga ccaaaacggt caaacttttc tttttgatca tatatttccc tactagatct
     7021 ccgacttcca tcatagaata atctgctcca aacaaaaaga gcgtcattcc gatcatcatg
     7081 attgccgcac caaccagaaa tgaagcgagg tcttctcctt ctaacggtgc aaaaacaaac
     7141 gttaaaatga caatcaggac agtcatcggc aatatagcag caatcacttc tttaaaattt
     7201 tttagcatgt atcctcctcc tttactcttt aagtttacct taaaatgaaa gagttttcga
     7261 gcacaaactt aaaacgttat catttaattt ttctcaacat aaaataacac acgtcccaaa
     7321 agtatctttt tacttggaaa aatgactttg aaggaacgcg cttattgtgt ttttttattt
     7381 tacagagccg atcattcctt gaacgaattg cttttgcaaa acaaaaaata cgatggcagt
     7441 tggtaaagta gcgatgacta atccagccat gatcattcca tagtctggtg tataggaagc
     7501 acccatagca gataaaacaa gcggaaccgt ccgtttatca ggagattgca aagctactaa
     7561 gggccataaa taattgttcc agctactcat gaatgtgatg attgcagccg cggcataggt
     7621 atttttagcc gtcggcatat acactctaaa aaaaatactt agttctttta gaccgtctaa
     7681 tcgagcggct tctactagat cttttggaaa agatttaaca ttttgtcgaa agaagaagat
     7741 caaaaaagca gtgctaacag atggcaggat gacaaccaag aaactgttga ttcccaaaac
     7801 cgttccgttc aattgtgaaa acattcgata taaagggatc atcaatgccg caaaaggaac
     7861 catcatcgat agcagtagaa tattgaaaat taggtctttt cgtttacttt gataaatctc
     7921 aaatccatat cctgccattg acgaaatcag caatgcaaac acagtggtca ccaaagcgat
     7981 catcgctgaa ttccaaaggg aacgagtaaa attcagctca ttggaaaaca aattttgaaa
     8041 attgatgatc aagttactgc caatctttat ttttcccgat gtgatatcca cgggtgtatt
     8101 cgtcattccc aaaaccatcc agacaaaagg gaaaatggaa ataaatgata ggatgcttaa
     8161 tgctgtatac tttaatactg acccaattgt cgaacgaagt tctaatgctt gttttttgac
     8221 gttggggcgt tcgattgttt ctttttctac catatttttc atcgactttc tcctcctact
     8281 ttcgtttgga ttatcgacaa tatcacaata aaggaaacaa taacaaagga aactgctgcc
     8341 gcatatccaa aattaggcgt gaatttataa ctcaaattat agatgtattg agatagggtg
     8401 gtcgttgcat ttgctggtcc cccgccagta atattttgta cttcatcaaa aagctgcaat
     8461 gtcccgatcg tcgaagtaat ggaagtaaac aaaatgattg gttttaaatt tgggatcgtc
     8521 actttgataa actgctgcca tttagaagca ccgtcaatag atgctgcttc ataaatctcc
     8581 gaatcaatat tttgcatgcc tgaaaggaaa aaaatcatat tgtatccagt ccaacgccaa
     8641 gtgatcgaaa gaatgatcag aactctcgcc caaattggat gagtcaacca gccaatcggt
     8701 gtgtcaatca taccaatgcc caacaacaag ttgtttacaa ggccagattg agaaaataga
     8761 cttttcatga tcagagaata actgaccatc gaagtgatac atggaagaaa gatagcggtt
     8821 cgaaacaacc ctttatattt caacttttta tcatttaaaa ggttggaaat aaaaagtgct
     8881 agaaacaaca tgatcggtac ttgtacaagt aaatacagga atgtattaaa aaaagctttt
     8941 ttaaaagttg catctgtcaa catccgctga taattaccta acccgttaaa tgtcatattg
     9001 acagggggac cactttgaaa agacgtgatc aaagccaaaa ccatcggaat aaaaaccatg
     9061 attgatatca aaatgactgg caagattaaa aaagcatgcc cgtttttgaa taaatctttc
     9121 tgcttcattc ttttccctcc aattctatca ttgattatct acatgaaaag acaagaaaga
     9181 caatatctgt aaggcagacg tgatcttttt tgtcttttcg tttgtctgat gaaaaagcga
     9241 agaaattcac ttttttacca ccgatcaatt agccaattgt gcttctactt gtttttgtgt
     9301 atctgctagt accttgtctg tctcttctcc attgatgatt cgatgaagag cttcagctac
     9361 gactgcttca attgcatagg tctcatgtcc gtaattcact tctggtattt cagatgtcca
     9421 tgttgaaaaa tcgtcaaaga tcttttgacc actgtaaaat tcagaagctt cttgataagc
     9481 ttcttgttca ttcgcgctaa gcatcgtaga tactagtccg atttctttcg caagagtgcc
     9541 catcagttct tcattcgaag caaacgttgc ttctaggaaa tctttcgctg aatcttctcc
     9601 agctactcct ttgatcacat accagccagc gccgccaagg ttagaagctt gcgctttttg
     9661 cagattttct ggaagtgcag gtattggtgc aatcttccat tttccagatt ggttttctgc
     9721 tccttggatc gttgaagaat accaagcgcc agttgggcta gaagctactg ctcctgattg
     9781 tatcgcagtt actccagcat tccagtcaga ggtttgttcg actagatctt ctttcaaaag
     9841 agtggcaaac aattcaagac catactttaa agatgcattg tcttggatcg tgactgtctc
     9901 cccatcttca gatgtatacc attctcctgc ctgttgcata atcatcctta ctcgaccaag
     9961 gtcagaagga ttgacttcag cgattttctt tcccgtcttt tctttgacat ctcgcgctac
    10021 ttgaatatac tcgtcccact tcagattctc catatcctct tctgtataac ctgcttctgc
    10081 catcagatcc gtacgataga agtttgctgt tacgcccgaa tcgaaaggaa caccgtatat
    10141 tttatctcct actttgttta ccgcaaattt atacggtgca aaatgatctt cctttacaat
    10201 agcagacaaa ttagcgaatg catctggata agaagtcaaa tagccttgta tcctataatc
    10261 ttcaatcaag acgatattgg gcaatccttc tgtattcccg ctcgctaaag cggtgttcag
    10321 tttctgaacg atatcatcct gagacatcgt aacaacttct atctctgttt cttcgttctc
    10381 ataaactttt tttgcttcat tcactgcttt gatattgaat gtctcatccc acgcccagac
    10441 agtgactttt tcttctttgt ctgctgtact actagcactt ccgcatcctg ttaagaaacc
    10501 tgatgctgcc gctaaacaaa cgactccagc aattaacttt ctgatgttca tttttatccg
    10561 ctccttttcc atccattagt tgtttacgtt tgctacattc atcataccaa aatttgaaaa
    10621 cggtttcttt attattcaga tacttcaaaa atttctccta aaataataaa aaaatacaaa
    10681 tcaactatga caaaaggaat aatcttagca tctagaccaa agatcgaaat ggtgaggttt
    10741 ctttaaaata aaaatatcct tgcattttct cctagaaata agtattttta aattacaaga
    10801 ctattcttaa ggcgggtaaa aaaatgccaa tacgcgtaat tcttatcgat gatgaacaga
    10861 cgattttaga tggaatgaaa cagttgatca attggtctga gcacgggttt caattaatag
    10921 ggactttttc cagtccgctg aaagcgcttg atttttcttt ggtacatgca atcgatatcg
    10981 tggtcacaga tgtaatgatg cctgaattaa atggaatcga attatcgcgg ctattaaaac
    11041 agcaacaacc tgaaacacag atccttatcc tctctagcta tgatgaattt gatatggtta
    11101 aagattcttt taaagaaggc gtcgctgatt atcttttaaa gcctcgattg agtcctgatt
    11161 tttttctaaa ttccttaact gccgtttcac aaaaaatcaa aaaaaagccc aacaaaagcc
    11221 caatcaccaa tcgttatgag cagatctgcg agaatctttc acagcagatt gctggacaaa
    11281 ctcgtccatt gcttgaccct cttctttttg aacacacctt gtttttctgt tatataccga
    11341 aaaacggcca ttcagttcaa aacaaggctc taaacaaaaa cagtcgatca cccattcatt
    11401 gatggatagc gacgattcgt ttactattta tcctgtttct accttttcgg aagaatccgg
    11461 ctatgtaatc aatactgatt ccaaagatac acttaggaag tttgttcaaa agtttcgtca
    11521 agaagttttt ccaggtgatt tttttgttgt ttctgattct tttgcaatcc aagatatcaa
    11581 tgaaatattc caagagatca gaaattgcac caaaggacaa cgtttctatc ataagggaaa
    11641 gaaccttgct tatcagcatg aacttcttcc gttattaacc aaccacgagc agcaagcaag
    11701 tagttattta acaaaaatcg ttcataaaga ctacgcttta gctgtcaaag aacttgagaa
    11761 tttcttcacg acgatattgg aacagcctat tgatccagct tatttgaaac atgaggcaat
    11821 caatcgtttc tatgcattac tcaacgcttt ggctgacgag catgttggga atgaagaact
    11881 ttctttgctc aagatcgccc ttccttcttt attagccgat gctgagtatt tcgaagattt
    11941 ttctattctt gtcaaagaaa cacttgagaa actcacccac ttttctgcaa atgcaaaaaa
    12001 agacaatttc gatatcttga ctttgatcta cgagttcgtc caggaaaatt atgagaaaga
    12061 aatcaattta caacttttat ccgaaaaata tcatttttca tatagctatc tctcagccat
    12121 ctttactgaa aaatttggta tcaacttttc aaaatatcta aaaaaagtcc gtatcagtaa
    12181 agccaagctc tttttgacgg aaacacggct tactttgacg gaaatctgtg agaaagtcgg
    12241 ctataccgaa ctgggttatt tctccagagt ttttaaagaa gagacaggaa tgacaccttc
    12301 tcaataccgt aaaggaactt ttgtaaaatg agaaaaaaaa tcaaagagca tgaactcttt
    12361 gccaaacttc tgttcatttt gttcatcggt ctttttctgc aagccatcgt catttctttg
    12421 tttatttatc atcgatcaag ggatgcctat atccagctgt tcaatcaatc gaatgatgtg
    12481 gtactaaaaa agattcaatc tgaatttgaa agtttgaatg atacaatcga gaatacatta
    12541 gccgcttttg attctaatcc agctgtcaaa agctattttt ccaatgatcc agcccaacat
    12601 atggaacagc ttcagcaact aagaacaatc caaaaaatga atgactctct ttcaaaaatc
    12661 catccaatga tcgattacga tgtattgatc tttggagaaa atggaagaac ttttgtcgga
    12721 aacgacatgc tcactgccgt atctgccgat tctttttttc aatctgcgat tgctcagaga
    12781 gtgaatgaac gtgctgctga tacacaaatg ctttttgcac accacggatt gactcttcgc
    12841 gataagaaag cacccagcgt cttctttgtc aaaaaactga aaaatacatt gaatcacgtt
    12901 tacggatatg ctgttttatc gatctcatcc aagcaactag cgaatctttt tcaatctgta
    12961 gtaaatcctg agatatcgaa gatctccttc atgaacgaag aacagacgat catcgcatca
    13021 aatgaagaaa atacaattgg gagccgatca atgattttca aaaaactaac agtaggtgaa
    13081 acaacgattt caaatggaca gcagttgacc cgtcttcctc tgtaccgcca ggattgtaca
    13141 ttactcagtc aagtcgatct tcattcttta tctaaccaaa tgggcgtgat ttttccgatt
    13201 attttgtata atatcgtgac acttgctttt gctggctcat tggtatttat gtatttggat
    13261 cgacacacaa aatcgatcta ccgcttgatt gattcgctaa aacggctaga ggaagatggc
    13321 ttaaaagcta ctgttcctgt acaaggaagc catgaagtcc aattgctagg gaatacgatc
    13381 aatcaattgc taagtaatgc tcagcatcat tatgaacaga cgatccaaga cgaaaagaag
    13441 aaacgttcgc ttgaaatcca aactatgcaa gcacagatac agccccattt tatttataat
    13501 acgctgacta gcttgaaatt tttgatttgg cagaaaaaaa cagatgaagc agttcaagga
    13561 atcgacagtt tcattacttt actaagaagt acgattggga aaaaagaaga agtgattcca
    13621 gtcaaggaag aaatcaaaag cgtacaaagt tacatcgatc ttttgagtat gcgatatggc
    13681 gaaagaatct cggctaaaat aatgattcct gatgaactgc agtcattatc tatgccgaat
    13741 atgatccttc aaccaattat cgaaaacgcc tatcttcatg cttttcacaa taaaacgcaa
    13801 ggattcatca cggtgtacgg caaaacaaaa aatcagcttc ttttattcga agtgattgat
    13861 aacggcgatg gcttcgatac tgaaaatacc aaacaaaaaa atgatcattt ttcaggaatc
    13921 ggcatcagcc atgtagatga gcggatacgc ctaatgtatg gcgatgcata tggcttaacg
    13981 atccaatcag tgattgggac aggaacgact gtaacgattt gtctaccgct tcttcctaaa
    14041 aatcaatcag aatatcaaaa ataaagaata gccaagcgct gattttttta ttttaagtta
    14101 aataaatcaa tcagtattct tgactttcat ctacgcgtct cttctactgt cagcactgga
    14161 taacagccca atatttgact ttctcctccg agcatcttga tttcttggag cgcattctct
    14221 actaatgtca ttggacggtc caacaacaaa tcgatcacga aaaaatattc tcccaagcta
    14281 gttttcaatg gtcgggattc aatcttactt aagttgattt cccgccagcc aaaagctgcc
    14341 agcattttat gaagcatccc tggccgatta gcaggtagtg tcaagatgac actcattttt
    14401 actggagctg actgctggct ggtcatcttt cggtcaccga cgatccaaaa acgtgtctgg
    14461 ttcaactcat tatcttggat attctcagct aagatctcca atccaacatg ctgtgctgtt
    14521 tctaatgaag caatcgctgc tgcgtcttct ttcggatgtt ctgctacata cattgctgca
    14581 gcagttgttg attctgttgc tactaaagga acattaggat aatgcgtttc taaaaactgt
    14641 tgtgattgtg ctagtgcttg tggatgtgaa aggatttttg taatctttgt tgctggattg
    14701 cctaaaagct gctgcttgat aggaagaacg atttcacttt taacttcgac ttctggatgt
    14761 ttggaaagaa gatcgattgt gtgatgaaca gctccttcca atgaattctc tacaggaacg
    14821 acagccagat cgacttgttt gcgaaacaaa gcgcgcaaac aaacagggat ggaagcatac
    14881 gcagtcaatt gttctgtagg aaatagctga caagccgcct gataagtgaa tgaactttct
    14941 ggccctagat agctgacgtt catatgcttt tgatcctttc tataatggta tcgatgatct
    15001 tttctggtgt ttgattggtc gtgttgattc gatgtgtcgc actttcttca taccaagaaa
    15061 gtcgttgtgc caataatgct tttatttctt ctcttgtttt tccaagagct aaaggtcgaa
    15121 tagacgtttc atcttgttgg atacgatcaa ctagacagtc cgcttctgcc tctaagtaaa
    15181 gaacaatcgg ctgtgttttt aaaaaacgcc gattttctgc actttggaca atccctccac
    15241 cagtcgcgat aattttgtct tcatttgaca gctttcttaa aatatctgac tccacttttc
    15301 gaaagctttt ttcaccgtaa tagtgaaaat attcggcaat cgacaattgg atatgttcct
    15361 caatctttgt atctaaatct acatactctt tttgtaaaca ttgagctaac cctttaccga
    15421 ttgttgtttt tccagcgccc atgaaaccaa tcagcaaaat gctagccatg agcttctcct
    15481 cctgacacaa gttctgctaa atcgtcaaaa aatgccggat aagagattga aacagcttca
    15541 gctccttcta gttcgcaagg tccatcagct atcaaagcag ctacttgcag catcataccg
    15601 attcgatgat cgcctctgct ggacactttt gcgccatgca gaggtgtcgg cccatggatg
    15661 atcagaccgt ctgctgtcgc ttttatcttt gctcccattt tctgtaattc ttctgccacc
    15721 gcatcaattc tgttggtttc ttttactttt aattcttctg cgtctttgat gatcgtgatt
    15781 ccttctgctt gagtagccac taaagctaga atgggcaatt catcaatcag acgcggaatg
    15841 atttctccac caatcgttgc tttcttcaaa tgactcgtct tgacacttaa atcagccgat
    15901 tggttctgtt cattgtgatt cgtctgggta atcgctgcgc ccatctcctc caacacatct
    15961 aagataccag ttcttgttgg attgaccccg acatttttta acaacagttg gctttccgga
    16021 acaagaagtc ctgctgctag aaagaaagca gctgatgaaa tatcacctgg aacagttatc
    16081 tgttgaccag ttaatttttg cggtccggtc actatgatcg ttttatcttc cactgtgatc
    16141 cttccgccaa attgacgaat catttcttcc gtatggttac gggaacgttc tttttcaacg
    16201 attacggatg tgccttctgc ttgtaatgcc gcaaacagca aagcagattt gacttgcgca
    16261 ctggctacag gcatattgta tcggataggt gataaagagc gggttcctgt cacagtgatt
    16321 ggtagatact ggtcattttc ttctccttgc aagtcagcgc ccatctcgcg taaaggttcc
    16381 atcactcgcc ccattggacg tttagacaac gaagcatccc cgaacagagt agtcgtaaaa
    16441 ggctgtccag ccaaaatacc catcaataaa cgtatggtcg taccggagtt tcccatgtca
    16501 attgattcgg ttggttggac aaatgagtgg ctaccgcgac catgaatctt gatcacctct
    16561 tcctcttctt cgatctcgac acctaattgt tggaaggcat gtaaagtact cagacaatct
    16621 tctgcgcgca aaaaattttg tatagtcgtc gttccttcag caattgctcc aaacatgatg
    16681 ctgcgatggg aaattgattt atctgctggt atcctaacag tccctcttaa tccatgtatt
    16741 tgttgtaata attgcattta tccagcctcc tatttgatcc agcaatgata actggtatta
    16801 gacataatga ttctttttgc ttgtaacaaa tcctgttggt ttttaaaact gatttgcagt
    16861 attcctaaaa tatcttccct ggtctcttgg atcttcaaat taatcaaaga aactcccgct
    16921 tttccgatca gtccagttac ttctgcaata acgccaggtt catctggcac atcgataaat
    16981 aaatcaaaaa aggcaggaat cgcgccttgc ttatggacag gcaactggtc tcgactttct
    17041 tttgcccgat tgaaaaaaga aaagatttcc gattggttct cagtcatgat ccattctgct
    17101 atttgtgtca tttcttgttg ccaatctgcc aatcgttcca ataatatctg cttattgctc
    17161 aacaaaatat ctgtccacat gacaggatct gaggaagcga tcctagtgat atctcgaaag
    17221 cctcctgctg ccagttgttt ggctcgcgga tactcttgat tgaattgttc tgcctgattg
    17281 actaagccag ctgccagaat atgtggaaaa tgacttagca ttcctgttat acggtcatgt
    17341 tctcttgctg taagagttac atattttgct ttggttccgc aaaatagttc ttgcagtttt
    17401 tcaacatctt ttttcgtctt ttccaaaggt gtaaagatgt aataggcatt ttcaaatagt
    17461 ttagcatctg ctgcctgtat acctgattta tgagaaccag ccattggatg tccaccgaca
    17521 aaccgaagat ttttctgctc agcggatgtc acgacttgct gcttcgtact gctgacatcc
    17581 gtaatgatga cgtgatcaga caagttgatt ctttcaagga catcaagata agctaaggtt
    17641 gtacggacgg gaacggctaa taagataacg tctgcttgtt ctgcacctgt ttcaaaatca
    17701 cttgcaacgt aatcaacgat ctgctgttct actgcttgct cacgggtttt tgactgacta
    17761 tcccaaccaa ctactatcag ttctggattg gtctgacgaa tacaaagtgc catagaagca
    17821 ccaatcagtc caagccccac gataaaaaca tgttgtgcca tcttatttgc ccccttttta
    17881 gtaatgtttc aagtagtcac ggtactcctt cactgcagct ttcaactcaa caagcgaatc
    17941 acttgggaat tttgacaata gctctgtcgc taccacagtg gctacaacat tttccgcaac
    18001 gacgctagct gcaggaactg ctgtactatc cgaacgttct acacttgctt tgtaaggttc
    18061 ttttgtatcg atatcaacac tttgaagtgg cttgtacaat gtaggaatgg gtttcatgac
    18121 cccgcgaatg acaagtggtt cgccattggt cattccgcct tcgaagccgc ctagattatt
    18181 ggtacgtcgg aaatagcctc tttcttcttc ccataggatc tcatccatca cttctgagcc
    18241 tggtaatgaa ccagaagtga atccgacccc aaattctacg cctttaaagg cattgatact
    18301 aaccacagct tgtgcgattt tggcatctag cttcgtgtcc cattgtacgt agcttcctaa
    18361 tccagctgga acgcctccaa cgagcacttc tacaattcct ccgatcgtat ctccattttt
    18421 ctttgtctga tcgatcaaat cttttattct ttgctcaact gctggatcaa caactcgtac
    18481 ttctgacgct tcagaaattt ctttgatttc ttgaatcgag atatttccag gtatttctgc
    18541 ttggattcca ccaagacaaa tcacgtgtcc tgctacgatg atgtcaagtt cttccagaat
    18601 tttcttggca attgcgccga ttgctacacg catggtcgtc tctcttgcag aggaccgttc
    18661 aagcacattc cgaagatctc gatgatggta tttcataccg cctaccaaat ccgcgtgtcc
    18721 tggacgcgga cgtgcaactc gccgcagtga ttggtctttt tcaggcactt ctgctacaga
    18781 catgacagtt gtccaatttt tccaatcttt attttctacc actaaagtga caggtgaacc
    18841 aattgttttg ccgtgacgga tgccagacgt gatccgaaca cgatcttttt cgatcttcat
    18901 ccttcctcct ctgccgtaac cagcttgtct gcgagcgagt tcgtgattga tttcttcttc
    18961 tgacagaggt aatcctgctg gtagtccttc aataatggct gttaattctg gtccatggga
    19021 ttctcccgca gtcatataac gcatcttaca gtcctcctaa gtaatctttg aatgtctctg
    19081 tgggaacagg aacgattttt gcttgcccaa tcttttctag caagatgata ttcaattggc
    19141 ttcctcttgc tttcttatca tgggttatcg cgtggaataa ttcatctgga tgacttagat
    19201 cgtacgtaat cggcagatgg aatttttgaa gtatcctttc taaagcagct gtcgatccag
    19261 ttggagacaa gccgattttt tctgcatgag aagtgatggc taccattcca atagctactc
    19321 cttctccatg actgactacc ccatatcctg ctgtattttc aattgcatgg ccaattgtat
    19381 gaccaaaatt taaaataagt cgatttcctt ggtcaaagac atcttcttcc actacttttc
    19441 gtttgatttc caacgtagca gtaatgattg gaacagcatg ttccagaaga tctttttcgt
    19501 ctttcagctc gttcagctgt ttccaaagcg ttgcatctgc tatagctgct gatttgatga
    19561 tttcagcgat tccttctcgt aaacgacgta ccggcaaagt ttttagaacc tcaggatcaa
    19621 tcaatacacc agctggctgg ctaaatgttc cgacaaggtt tttcgctttg tttgtattga
    19681 ctgctgtctt cccgccaata ctagaatcta cttgtgcaag tagcgtagtc ggaatttgaa
    19741 cgaaatggat cccacgcatg aacgtcgagg ccacgaatgc tgctagatca cccaccattc
    19801 ctccaccaag tgcaagtatc ccatcgctgc gggtaaaatc attatctgct aaaaaatcgt
    19861 ataactcagc tgcttgttct aaagatttac tggtctcacc cgccggtacg attgaaagga
    19921 ctggttcaaa attagcttgt ctcaattgga acatgatttt ttctgcatat agtggagcaa
    19981 cgtttgtatc agtgatcaca gctacttttt gaggtctcca aatcgtttga agccatgatc
    20041 cagcctgttc tagtgcgcct ttttcaatat gaatatcgta tttttggtta tcaacatgta
    20101 cagtaagcat tcgtttcact tctttctttt aaaaagctgg aattaatcga gtgtctgaat
    20161 cttttccatt gcttctttca tgatcgcaac ttctttcatc atgcgtgagt aagtcttttc
    20221 attcaacgat tggggaccgt ctgaccaagc atttgcagga tcaggatgga tctctacgat
    20281 catgccatct gctccgcttg ccacacccgc acgagccatt ggtggtacaa gttcccaaat
    20341 tcctgtacca tgacttggat caacaatcac agggaaatga gttaattttt tcatcaatgg
    20401 gacagcactt aaatcaaacg tattacgtgt cgctgtttcg taagtccgaa tcccacgttc
    20461 gataaaaatg acaggagatt tgtcttcgac tgcaatgtat tctgcagcat taagccattc
    20521 attgatcgta ccggaaattc cacgtttcaa tccaacaggt ttacctgttt taccgacagc
    20581 agatagcagt ttaaaatttt gcatattacg tgcgccaatc tgtaggatat cgctgtactc
    20641 agccaccata tcgatatgcc cttcatccat cacttcagta atcactttca ttccaaattc
    20701 atcagccgct tgacggatgt atttcaatcc ttcttcttct aaaccttgga aagcatatgg
    20761 agaagtacgt ggtttgaagg caccacctcg cagaattttt gcgcccccgg ctttggccat
    20821 tcgcgcacat tctctgattt ggtctaatcc ttcgatagaa caaggaccag ccatcgtcac
    20881 gaaactgccg tcaccaattt ttactccgtc tacatccacg actgtattgc caggatggaa
    20941 ttctcgagaa gtcaatttgt atgtgtttaa aatacgcaca gcattttcta ctccttcata
    21001 gcgtgtaaat gctccttctt gtaaacttcg cgtatcacct tttagtccaa tcactactcg
    21061 ttctgttcct tgatcgattg agactttgaa tccttctttt tcgatatgat cgacgacttt
    21121 ttttatttgt tcttccgttg cttctttttt cataattact atcattgttt ttcccgcttt
    21181 cttttgttta cttatctatc ttggctgatt ttctctactt tttcaaggtg gttttacatt
    21241 aattcctact aaatgaccgt gtcctgttgt tctcattttc gctccttctt tcctacttat
    21301 gacccagata atcaacaaaa aaagatgtcc ctgtaggaaa ttgcctctac agtgaacatc
    21361 ttcaacgagc cttaaaaagc gctgcaaaaa tataaaatag ccactataga tgaatttctc
    21421 tacgtggctg taagtcgtgt ttaaaaatct ttagccatca tagatacaaa cctggtttgt
    21481 ttgtacccac gaagtcatga atacaaacct atctaaaata gctaaagtaa tacgtattca
    21541 gttttgtaag ttttctagat ttcataaaaa atcgctccaa actgatgtaa gaattgtacc
    21601 tagtatagac ataaaaaaat cgactgtcaa tcatttttat gaaacttttt ttaattttct
    21661 gatagttaac tttgtttttc agaaaaataa caattggttt tattgaagaa aatagtcatg
    21721 aacaaaagta tctgagaact tttttactct cttgttcatg acatatagaa taaagcagct
    21781 ttgtcttgta aactccgttt ttcaaataat aatctaaaga ttgctactga ataataaagc
    21841 cgatttcatg gtcctcttcg ctgctgattc ggtaaggtga ctcaacatcc gctccccagc
    21901 tattgatacc cccgactcct cttacttttg caaaaatcgt aagaaccgtt cgtctttctg
    21961 gcggtagttc ttctatatgt gttgcctgtt ccagttcttc tgctttgaat ggtaaagcgg
    22021 aaaaagcaaa tggcgtatcc tgctgttcaa atcgcaacga aaaatcttct tgatctttat
    22081 ccgtattatc caacgtttga tttcttgtta gttctaccca tttcgtttcc atatgcatgc
    22141 cgcattcttg gggaacaagg tatggggaaa cggggagtcc tgccacttta taaatacctt
    22201 cgacaccacc agccatccga tccggatatg tttcccctga taggccttca tactcaaaaa
    22261 attttgcttt cgttggcata atgaacctta aacccaatgc gggtaattcc ggtaatcctt
    22321 tttgtccata ataatgcata ttgacaagca ttttaccctc tccagcgatt tggtaggaaa
    22381 ttgtcacttg ggtttttggt actgtgttga tttccagtgt aaaaatgatt tcaaccgttt
    22441 cagcgtattc attacttgaa tattgattat ttactggagc aatcggcaaa tcgatctttt
    22501 tattgtccac cagtacttct atttctttga cttttggata caatccggct cctaaccaca
    22561 taccggattt aaatccaaat ccgctacctc tgtcattatc ggtcgttgct cgccaaaaaa
    22621 ctggaagtgt ttcccggtat agccattctt ttccgttttt attgagcgat tccagtccgc
    22681 ctcttgtata agaaaaaata taatgcgtat tccccgattt gacacctaat gtacagtcgc
    22741 cgaagacgat tgcaactttt tccgtatcca tatgactttt atttactgta tttttcataa
    22801 taatatctta cctcctgcat ggcgggtttt tcttgtccat ctgcaaaaac gatcccattc
    22861 cctgagaatt catagtcact tggtttatcg tcaaagtcac cgccatagcg catcacttct
    22921 ctgcctgtga ttggatcagt cacttggatc gcctgatctt taaaatccca tatatagcct
    22981 ccttggtaca tttcataacg atcaagcaac gtcatgtaag aatccattcc acctaacgaa
    23041 ttccccatgt catgcatata ttcacataag atgaacggtt tttccgcttt attttcaagg
    23101 tagtcaatga tctcttctgg tggcgcatac atgcagcttt ttacatctga aatcgaatct
    23161 tcgaatgctg gatttggaaa attcccttca taatggacaa gtcgatcggg gtctactttt
    23221 ttgaagtaat cgttcatttg tcgaatgttt tcttccgcat aagattcatt tccaagagac
    23281 caaaaaagaa tacttggatg gttttttaat gtttcgaaat tcgtttttgc tcgatcaaga
    23341 acagccgcct gccactgagg tactgcacct ggtacgttgt aagaaggctc aaatgcgccc
    23401 attttttgcc atgagccatg ggattcgagg ttcgtttccg ccatcacatg gattcctgct
    23461 tggtcgcata aataatacca agtgatctgg ttggggtaat gagatgtccg tacgccgttg
    23521 atctttgcat tttttatgat agccaaatct ttttccatat cttctatagt gatggcgcgt
    23581 ccttttttcg gatgccactc atgtcgattt accccgttga taatcatccg ttttccattg
    23641 aagtagatga ttttatcttt gatttcgatt ttacgaaaac cgaaggaata gtcaatatac
    23701 tccgttactc ttttttcttc gtctatcgtc tccaattcaa gcttatataa attgggctga
    23761 aaatgccccc acagtgccac attttcaaat ccatcgatgc gaatcgtcat ttgctctttt
    23821 aacggatatt gctgttgata gatttccttc ccatcaggat ctagtatcgc tacattcagc
    23881 tgactgtttt tggctacttg ctcaaaagac aaatctactt caagtttgcc attttgacat
    23941 ttgtcatcta agcgaggttt gatccaaaga tcttctaaat ggttttgtcc tcgagcaact
    24001 aagaagacat ctctgaagat cccaaaaaat cggaaaaagt cctgatcttc caagaatgca
    24061 gctgtacttc ttttgtaaac ctccacagct agaatatttt cttcttccaa ataaggtgtt
    24121 aaatcaaatt cagacggagt gaacgaatct tcggcatacc cgataaaatg accattcaac
    24181 caaataaaca ttgcttgttc tacaccagca aaatgaatcg agatttgttt tccctttaga
    24241 ccttcttcta atcgaaaagt cgtcaaatac gaaccaaccg gattgtcttt agcagctgaa
    24301 aagatccctt ccgcctcttt ctcagggctt gtcgtgaaag ggggacggcg aaatacatgt
    24361 ccctcccacg gatacatcgt attgatgtaa tggatcttgt cataatttgc taattcaata
    24421 tgactaggaa cagtgatttc atcaaaagaa caggcatcaa aatctttttt ataaaatgtt
    24481 tttggtcgta ccgaaggatt tggcgaataa caaaaacgcc atgatccatt taaagactgt
    24541 ttaagggagg atgtggtttc tacttcttcc cttgttgcat aacaaacatg atcgctatgt
    24601 gcatttgatt ggttcactct aaaaacttgt ggatcatcta accattttat atttgctttc
    24661 atactttttt ccttctctct cataactttt tgaaatgaag cagttctgtt tggaaatcac
    24721 cttgaaaatc ggggaagtaa agtccaactg tcatcaattc ggcccccgaa aatatccgct
    24781 tcgaggtctg ttcctgataa agtgcctcat catctaaccc catcagatat acttcatgga
    24841 acgctggttg agctgaagct agtatcctcc ctaaaaacac aatagcttca tcttgtttag
    24901 gagacacaaa catccatgcg gcaatatttt cttcaaaagg actcgccaaa cgataataat
    24961 ggccatactg gatcaccgga cgaatcgttt gataggatat aatttggtct tttacttgct
    25021 tttcttcttc aggagacagc tttgtcaaat ccagttcata accaaaaaca gcgctcatag
    25081 ctgtttctcc tcttgttttc aacgaagtag atctgtcggt ctgatgattt ggtacagctg
    25141 atacatgagc tgtgatggac gaaatcggat aagcaaggct tgttccatat tggattttca
    25201 tacgctccac tgcatccgtg ttatcacttg tccatgactg cggcatataa taaataaacc
    25261 cggcatcaaa ccgtccacct ccaccagaac agccttccca taagatttcc ggataatcag
    25321 ttgtcaaatg ttcaagtagt tcataaagcc cgagcatata acgatgcgct acttctcctt
    25381 gtctctgtgg gtcaagggta atcgaataga catctgaaag cgaacggttc atatcccatt
    25441 tgatgtagtc aagaggaatc gtatctaaaa tctttctcat ttgtttctca atcgtctgcc
    25501 gaacatctaa ccttgtaaaa tccagtacat gttgtgatct ggaagcagaa ggcattctac
    25561 ctggctcctg cataagaaaa tcaggatgtg ttcgatacag ttcagaatca accgagatca
    25621 tttcaggttc aaaccataaa ccaaatttca atcctttgct atgagcataa tctgctattt
    25681 cacgtaatcc atttgtcaac ttgccttcat actcgaacca gtctcctaat gaagaattgt
    25741 ccgcatctct ttttccaaac cagccatcat ctaatacgaa catttcgatg cctagctcct
    25801 ttgcttcatc aatgatcgcc ttgatttttt cactattgaa gtcaaagtaa gtggcttccc
    25861 agttattgac cagaatcggc cgttcagcaa attgatgacg acctcttgcg attctttcac
    25921 gtagcaactc atggtggatc tgactcattt tgttcaatcc ctgacttgag taagaaagga
    25981 tcatttcagg tgtttgaaaa gactggcctg cattcaattc ccacgaaaaa cgatggctgt
    26041 tgatcccacc gacgactctc aattgattga tctgatcttt ttcaagttcg aaagaatggt
    26101 tgccggaata aacaaattga agtccgatcg cttctccagt attttctgtc gtatgatgat
    26161 gaactaaagc aataaagtta ttcatatggt gactgctcgt tcctcgacgg ctttcaaata
    26221 cttttgttcc agataaaaca gattgccgtg aaatctgtct ttcattgaca tgtgctcctg
    26281 gcaaagcaat gacttcatca aatcgcctag tatgggcaaa gtctagctgg aaactagccg
    26341 ctttttctag tttgattgtt tctccggttt catttcttat ctttacagat cgtgtgatca
    26401 ctgctctatc agtaaatatg gtatagaaca aatcgaaata aatcgctgtt tctctatcct
    26461 taagtgaaat caccaacgtt tgtgcctctg acttgtccat cacataagtt tgaggcaagc
    26521 cttcgatctc tggcttccca tctgtaatat aatggctgtc atatctcaga tccagtaagt
    26581 ctgatccatt cttgcgctga atgatcgatg cgggcgttcg aaagtccatg ctgccatgag
    26641 aagagtattc ttgcggtagt gtatctttcg acagagaccg gtcaggattt aagggaacat
    26701 ttcctgaaaa tccacgatct cttcggggat aatttttatt gtctttgtac tgcttgactg
    26761 gtttgccaaa ataaatatgc gccaatacat tgctttcttc tatctttatc agataagaaa
    26821 gaaatgtatt tcgtaaatgg aagactcggc tcttttcatc aaataagatg aaatttttat
    26881 ctgtttttct atgcgtaata tccatcattt cactcccaac aaaacggaaa ccgtttactt
    26941 ttttttataa ttcctgtata ctgtttacta aacaattttg tcaataaaaa ttttttattt
    27001 ttttgaggag tgtgtaaaaa tggttggaat tagagatgtc gcacgaaagg caaatgtctc
    27061 tcctgctaca gtttcccgtg tgttgaataa cgatcagacg atccatgtgg ctcagactac
    27121 tcggcaacgg atagtagagg cagctgctgc gttggattat gacatcagta ctcgtaaata
    27181 tatcaaaaag agaatgcctt cgattggtgt gatctctacg atcggcaaag cgagcgaaga
    27241 acaggatatc tattacaaac atttgcgagt agggatggaa gaagaagctc gacgtctgca
    27301 tttagggatg aatcgaatct ataatctatc tgataatcct aaacaatggg aagatctaga
    27361 tcagttaggt gcggtgatcg ttgttgggac tgttacgaaa gaatcgatta ccgccttgtt
    27421 aaaacaaaac atgcaaatag tcgtcgtgga taaccctgac atccagcaag aggtcgatat
    27481 ggtgtatgca gatcttgaac ggatgactaa aaccgtactg gaattgttct tagaaaatgg
    27541 tcataaaaga atagcctata tcgggggata taaagtcgat atggatgaat tcggtgggaa
    27601 gcagatttct ataaatgaaa agaggatgcg tgcctatcag cattttatga tcgatcatca
    27661 cttagaaaaa tatatgtctt atcatctagg tggctggaca gaaaaacaag gtgaggtact
    27721 tgcgactaat ctattagaaa atgaatcccc tcttcctact gccattcttg tcgggagcga
    27781 tccaatggca attggtgtct atcgggcatt gaaacaaaaa aatatccaaa ttggagaaga
    27841 gattgttgta gcaagctttg ataatatcga gacaatcgca aacctctccc ctggcttgac
    27901 cagtgttcaa atcaatgcga aatcaattgg gcaagcagct gttcgaatgg cattggagcg
    27961 aattgacggt atacgggacg aaccaatcat tttgacttat cctgcacgat tgattgttag
    28021 ggaaagtttt atcccaagaa caaaaaggta ttgaaagaga ggttgtgaaa agccgcttcg
    28081 tttcttcata ctcaaaacga aacggctttt tcacaacctc ttacttatac ttattcacaa
    28141 aatccaatgt ctgctggtaa caattttgcg attcttttag cgtgtaatca aattggtatt
    28201 catgggtaat ctcttttttt gtatctgtat aaaacaagga ttgcacgggt acctttaatt
    28261 ctgtcaaccg attttctaat gcttgacctt gctcctggaa tgagtatgca tttccgtcag
    28321 ttatatacgt tggcggaaat tccttagaaa catggtcagc cacactagct tctttcaatt
    28381 gctcactcgt tttccaatct tttgttccaa tcaacgacca cgcaacggtt ttgacgaaaa
    28441 acttcataaa tcgatcatcc gaatgctgct gtgctgttag cttcaaatca acaggtccgc
    28501 aataagaaat ggttcctttc agactatctt ttggaagtag atgtttgatt ttcatttgtt
    28561 tagcatacgc atcattcgtt tgtatagctg catattgcaa tgcgatttgt gaacctgcac
    28621 tatctccacc aaaaaataat tgttccatgt ctagcaattt gtcgtctttt tcttcagcta
    28681 ataaatcttt gatcagttca ttcacttgaa gaacttgatt agggtattct gaatcaggcg
    28741 ctaattcata attcatcgca accactgcga tgttggcgtc tgaaactaat tttgtcgcaa
    28801 attctttgac acccgattta tctccgccga cgaatcctcc accatgtacc caaaatagaa
    28861 caggaacagg ccccttgctg ttttttggat agtagatgtc ataagtattc tctttatact
    28921 tggactcata cgtcaaatct gtttttttcg ccacgttttt ttctgcttga tcgaacgttt
    28981 ttttatcagt gatttgaaca gtatttgaaa acatatggtt gatcaagaat gctccaggtc
    29041 tgggggaaag ctggaaggca agaaagattg caaacgcgat cccaagaatg attccgaaga
    29101 accatccgat aaatttaaga attttctttt tcataaggct ccctcagtag ttagtattaa
    29161 gcattctgat tataccatag tgttatttcc tatcaagctc tcctagatga tttaatgatt
    29221 ttccccaaac ttcttctgca atgcttttga caaaagaaat tttttccatt gttcttcaaa
    29281 caaaacattt tcttcttctg ttgaagcaaa tccacattga ggacttaagc acaaacgatc
    29341 caaaggcaga tatcgtgtcg cttcgtagat ccggtcaatc acttgctggt gctcttccat
    29401 ttcgccattt ttcgttacag tcaaaatcta agacaactaa tttatcttca gagactttct
    29461 ctaaaagaac aaaactccca gcacgttcac tatcgtattc taaataatag gcacggacat
    29521 tttcttgagt aaaataatgg gtctgctacg tcgtcatccc ccctgatgcc gccaaaatcg
    29581 aataataatt tccgcgtcaa acatgtatat ttagtgttga atcatttgag aatatgaaaa
    29641 taaaaatctt tttgatcaat cagttaatca aattgaaata acgaaaaatc tgagacagaa
    29701 tgacgttcat tctgacccag atttgatttt gcacaactca acagtcctta ttggcaaatc
    29761 gccaaaataa tgtagactaa ctaaaaagac taagaaacaa taacaaaagt taacacttct
    29821 tagtctttct ttagcacgtc tatttattaa agattttagg gccttttctc atgtttttac
    29881 gatcattctt aggtgtttcc atttgtttgg atcggcctcc accttgtttc tttttgatca
    29941 attctttcat tttttctttt tggtccattt ttattctcct ttaacgaatg aagcgactaa
    30001 ttcgatatga tgggtttgcg ggaaaagatc tacaggctga actttcttca cggcataacc
    30061 tgcttctgca aataacttag catctcttgc aaaagttgcc ggattacatg agatatagac
    30121 gattcgttct ggtgacattt cgattgctga ttcaataaaa tgatgatcta atccttttcg
    30181 tggagggtca actacgatca cagatggttt gatccctttt tcttgccatt ttttcataac
    30241 tttttctgct tttccgactt cataatgaac attttcgatt ttattattta aagcattgaa
    30301 ctgtgcatct tcaattgctt ctggaataac ttccatccca tacaccttat ccactctgtc
    30361 tgctaaagac aagccaatcg tacctattcc tgaataagcg tcgatcacaa tgtctttttt
    30421 atctaactcg gcaaactcga tggctgtttg gtacagatac tctgcttgtt gagtatttac
    30481 ttgataaaat gactttgctg agattcgata ggtttttcct aatagctgat cttcgatata
    30541 gtctctgcca tataaaactt tttctttgtc tcctaaaatc acatttgttt tttcttcatt
    30601 gatattttgg atgaccgaaa ccacttctgg caattcttca tgaatagctt cagcaatttc
    30661 cttggattta aagaattttt ctttacgagt aactaaaacg accatcattt catgggaata
    30721 atgaccacga cggataatga tgtgacgaag ctgtccttca tttttttctt cattatatcc
    30781 tcgtacttgg aaccgttgca agatatctct gactactttg attgcttgat cgatgacagg
    30841 atcttggata taaaaatctt cgatagggac tagatcatgg ctattctttt tgtaaaaacc
    30901 ggtggctaac tgtccatcga tacggcgaac agggatctgt gctttattac ggtagccgaa
    30961 tggttctgcc attccgaccg ttggaagtac aggaacttct ggcatcttag caatcttcgc
    31021 cattacatgc tctacttgtt tttgtttgaa gacaagctgt tgttcatact tcaaatgggc
    31081 taaaggtgcg atacctatgc gaagtaatgc attgttttct acaggctgac gatcaggtga
    31141 ttgtgtaata aatgtttcga cttttccata tccaaactta ttgcctgctt ttactactag
    31201 tatttctact tcttctccag ggagtgcatt ttcgataaat aatggataac catcgatttt
    31261 tgctaccccc attccttcat aactcaagtc gacgatttcg actgtatatc gttcgttttt
    31321 ctttactatt tgctgttctg tcatattttg ctcctttaag cctatttttc aatcctactg
    31381 aactctacta taaatcagct aattacacaa ctaaaaccgg cactgacctt actacgttca
    31441 gcaccggctt ttgattaatt cttttgatta ggtgtttcgt ctgctatttt tccgtcaccg
    31501 tcgatatctt catccgttaa acgttcgact tcttttacga attctttgct gacaacctct
    31561 aattcttctt catctgtacc tgtgattgct tcatcaggaa tctgatcggt attggcaaag
    31621 aactcaatgt gttgatgaag attttggaaa tgcatcggtg cttccccgcc gtattcacca
    31681 tctaagttga tcattactgg tcgattgata tcatcttctg tttcaacgaa caaactgctt
    31741 gttttggtat agattattct tggatcatcg acatgtcgac cgccattcag catgagtgct
    31801 gcaatatgca agatctcaaa gatatttgct gtcttcacaa tgattaaaga aaacttccca
    31861 tcatccaatt tggcatctgg cgcgatctgt tcgaatcctc caacagagtt cgtcagccct
    31921 aggaaaaaca tcgaagcatt tccgatatat tccccttcat catacttcaa gcgcattttg
    31981 attggcttta ctcgagggag catctctgct cctttcgcaa gataagcaag ataaccaaaa
    32041 atactcttta gttctgatgg aacttcataa gtcaattctg tcaaatagcc acctgcagcg
    32101 atattgatga agtaactgtt atcagaaagg ccgatgtcca tttttacggt ttggtgtttt
    32161 tttatcactt ctgctgctgc tttaatatta tctctaggaa tttttaatgc tcgagcatag
    32221 tcgttcgttg taccagctgg gatgatggcc attttaggac ggtgttcaag cggagcgatt
    32281 ccattaacca cttcgttgat tgtgccatcg ccaccagctg ccactactag atcaaaacct
    32341 agttctgcga ctctacatgc ttcattcttg gctgaatctg gttctggtgt agttgcatag
    32401 gcgctggctt caaatcctgc ttcttctaat gcctgtagga tatccgccaa attttttttc
    32461 aataattctt ttcccgaggt ggggttataa attacgcgtg cttttttcat tttcagcctc
    32521 tatcgtttcg ctaattcatc tttaagtagc ttattcacga caccaggatt tgcttgtcct
    32581 ttagttgctt tcatgatttg accgactagg aagccaaccg cacgatcttt tccatttttg
    32641 aaatcatcga cagattgttg gttgttatcc aaaatttcat taatgattgg cagtagtttg
    32701 ttcggatcag ataattgcac ccaaccattt ttttcaacta cttcttgggc ttctccgcca
    32761 tttgtgatca attcacggaa gacttttttg gcgatttttg agctgatcgt tccatcggcg
    32821 atcaaacgaa tcattcctgc taagttctca ggtgtcaatt ttgtctcagc taattccagt
    32881 ttctcactgt tcaagtaagc agaaacttca cccatcaacc agttagatgc ttgcttggca
    32941 tctgcaccat tttccaaaac agcttcaaaa aaatcagaca tttcttttgt aagtgtcaat
    33001 accattgcgt catactctgg aagtccaaac tcacggatat agcgttcgcg acgagaagct
    33061 ggcatctcag gcaaactagc ttttactttt tgaatccatt cgtcatcgat cacgaatttc
    33121 gggatatcag gctctgggaa gtaacgataa tcactagacc cttctttgac acgcatcaaa
    33181 actgttttat tcgttgtttc gtcaaaacgg cgtgtttctt gttggatttc tcctcctgaa
    33241 agaagaactt ttgcttgacg tttttcttca aaagctaaac cttttttcac gaaagataaa
    33301 gagttcaagt ttttcaattc tgctttcgta ccgaactctt cttgtccata agggcgaaga
    33361 gaaatattgg catcacagcg catagagcct tcttccattt tcacatcgct gacttctgta
    33421 aattggataa ttgatcgcaa tgcttctaga taagcgtatg cttcttctgg tgaacgcata
    33481 tcagcttcag aaacgatttc gatcaaaggc gtgccttgtc ggttcaaatc aacgtaagaa
    33541 taaccgccaa taccatgcat gttttttcca gcatcttctt ctaaatggac acgttcgatc
    33601 cggatttttt tctttttacc ttctacttcg atttcgatcc atccgtcatg accgattggt
    33661 tgatcaaatt gggaaatttg atatgctttt ggattatctg ggtaaaagta atttttccgg
    33721 tcaaaatgag tatctttaga gatttcacag tttaatgcca aagctgcttt catcccgaat
    33781 tccagcgcag ctttattcat tactggcagc acgcctggat aaccccagtc gatcacgttt
    33841 gtattgctgt ttggttctgc accaaaatga gctggcgctg gagagaaaat ttttgagttg
    33901 gtttttaact cgacgtggac ttctagtcca atgactgttt caaaattcat tcgtctttcc
    33961 ctcctaaaat agctggttgt tgtttatgga attctgttgc ttgttcaaac gcatatgccg
    34021 cttgatacat cgttttttca tcaaaataat taccgatgat ctgcaatcca actggtaatc
    34081 cttctgataa acctgccggt acagacatac ctggaagtcc agccaagttg acagggatcg
    34141 ttaagatgtc actcatgtac attgtgattg gatcgttaat gttctcaccg attccgaatg
    34201 caactgttgg tgaagatggc ccgatgatca agtcataatc tgcaaagact ttttcaaaat
    34261 ctcgtttgat caatgtacgg acttgtcctg cttttttgaa gtaagcgtca taataacccg
    34321 cgcttaagga gaatgtacct aacatgatac ggcgttttac ttcttcaccg aatccttctg
    34381 aacgtgagtt gacatataca tcatctaatg atttcacatt ttcagagcga taaccgtagc
    34441 ggataccatc gaatcgttgc aaattggaac ttgcttctga tgaggcaatg atataataaa
    34501 cagccacacc gtattttgaa tgaggcaagc tgacttcttc cacaacagca cctaatgaac
    34561 ggaatgtttc tgctgctttc aatacagctt cttttacgcc aggggccaca ccttcgccta
    34621 agtattcttt aggtaaagca atcttcattc ctttgatgtc gcctgtcagt ccctctgcaa
    34681 aatcaggaac tgaaacgcct gaagaagtac cgtctttttc gtcataaccg ctgatagctg
    34741 tcaatgctaa tgcattatct ttcaccgtac gggtcattgg tccgatttgg tcaagagatg
    34801 aagcaaaggc aatcaaacca aaacgtgaga cacggccata agtaggtttc atccctacga
    34861 tgccgttaaa agctgctggt tggcggatac ttcccccagt atcactacct aaagaaactg
    34921 gaatttgtcc agctgcaact gctgctgcag aaccaccaga agagccacca ggtacttttg
    34981 ttgggtccca agcatttttt gttttcttga aataagaagt ttctgtactt ccacccatag
    35041 caaattcatc catgtttagc ttaccaacag ggatcatatc tgcttgatag attttatcca
    35101 tgaccgttgc atcataaatt ggttcaaaat tgtaaaggat cttagatgca gcggttgtca
    35161 agatatcttt tgttacgata ttatccttga taccaattgg aataccagca aggacgttgc
    35221 tttcatcaat ccctttttca tctaaagctt ttgcctgttc caatgctttt tcttcgttca
    35281 atgtaatgaa tgcctcgacc tcaggctctg tttctttgat tcgttcaaat gttgtttttg
    35341 tcaaatcttg tacagtgatt tctttcgata caagcatatg atgcagttct tctagagaac
    35401 gattgtgtaa ttctgtcatt atgcgccagc ctccccatta tcgatgattg cgggtacttt
    35461 gataaagccg tcttctgttt ccggcacatt tttcaataat tcatcgcggt tccatccagc
    35521 ttgcgcccga tcttgtcgca tcacgtttac tgtttcaacc acattcgacg taaatggaac
    35581 accttccgta tctacttctt ccagcatttc aaccatatcg atgattttac ctaattggtc
    35641 ggtaaaactt gcaagttctt catctgcgaa cgcaagtttt gctaatttgg caacgtgttt
    35701 cacttgttct tcactaatcg ccatactacc ccttctttct aaacgagtta aaaactttgc
    35761 tctctatttt aacacaagag tgccgtgtct gaaattgttt attgaaattt gtctgaaaaa
    35821 actcattttt cattcttcta ctgagcgact tttagccaat gcatctgcca tttgatcttc
    35881 tgtccaaact tcgattccta attcttgtgc tttggtcagc ttgctgccag catcttctcc
    35941 tgctaccacg atatccgttt ttttcgatac gctaccagtc actttcccgc caagattttc
    36001 gatcgtctct tttgcttctt cacgagtaaa tcgtgttagt ttaccagtaa ggactactgt
    36061 tttttcttta aaaggagact cgacttcttg caattgggca tttcgaagcc ctttgtattc
    36121 gaaattgacg cctgcttgtt ttaattcatt catcaattca tggacttctt cgttactgaa
    36181 ataagtgact acactgtcgg caatgatatc accgatcgta tcaagcgcaa taatcgactc
    36241 atagtcactt ttactcaatg tttctagatc accgaaatgt tctgctaaaa tttttgctgc
    36301 tttcgctccg acatgtcgga ttcctaaccc gaaaatcaac cgctcgaccg aattatcttt
    36361 gctgttgtcg attgctgtca aaatattatt tgctgatttt tcttttattt tgtccaacgt
    36421 caataactct tcttctgtca atttgtaaag atcagcaaca tctgctacta gttttttatc
    36481 atacatctgt tctagtacgc gcggccccaa cccatcgata ttcatcgcat ttcttgaaac
    36541 aaagtggttc aaaccttctt tcatttgagc agggcattta ggattgatgc accgtaaggc
    36601 tacttcttca tccaaatgga caagttcact tccacaaact ggacaatgtg taggcaattg
    36661 gtattcttcg ctgtctttag gtcgtttatc taacacgact tgcgaaactt ctgggatgat
    36721 gtctcccgct ttataaatca gaactgtatc tttcaagcgg atatccttca acttaatata
    36781 atcaccgtta tgcaggctgg cacggcttac tgtcgttcct gctactcgga ctggtgtcat
    36841 gatagctgtt ggcgttacta cccctgttcg accgactgtc cattcgatgt tttcgattag
    36901 cgtttcaact tcttctggcg gaaacttgta agctgctgcc catctcggtg ctttgatagt
    36961 aaaaccaagt tgatcttgta gcgagaattc attcactttg atgacgattc catcgatttc
    37021 atagggcaaa tccacacgtt tgtcatgata ttcttcaatg tatgaccaca cttcatcaat
    37081 cgaatgacat agacgttttt cccgattcgt gtggaatcca attttttcta gctcttctag
    37141 cgcatcatac tgggtttttg cttgcatagg accgaaatca gctactgtgt ataaaaaagt
    37201 gtccagattt cttttcgctg tgattttaga atctaactga cgcaaagaac cagctgcggc
    37261 gttccgagga ttcgcaaaga tatcttttcc ctctgcttct ctgtcttggt tcaattggac
    37321 aaatgaccgt tttggcatga aacattcgcc tcttacttcg atgttcattg gttcttttaa
    37381 tttgattggg accgaccgga cagtttttag gttttcagtg atgttttctc ctacagttcc
    37441 atccccgcga gtcgcacctc tcacgaaatt tccatcttca taacgcaaag aaacggaaag
    37501 tccatctatt tttagttcac agcaatagtc aactacacgt cccactgctt tttgtacacg
    37561 ttgatcaaaa gctatcagct cttctttgct gaaaacgtcg ttcaaactgt aaagcggaat
    37621 atcatgagtg actttttcaa aaccttctaa tacttttccg cctactcgtt gagtgggaga
    37681 atcagacgtg atcaaatcag gatattgttc ctcgattgct actaattctg cgtattcttt
    37741 atcataaaca tagtcttcca ctgttggttt atcttctacg tagtattcgc gagaccattg
    37801 gttcagtctt gtacgaagtt cttctgctcg tttagcagct tcgtcaatcg tcatttcatg
    37861 ttccatcatt taccctccac tactaagctt tttcaattgg cgcaaaggca gccaaaagac
    37921 gttttactcc ttgacttggg aaagccacat ctagttctag atccttcgac gtcccgctta
    37981 ctcggacgac tgttcctaga ccccattttt tgtgtttgac tttatctcca ggtttccagc
    38041 tgttattttc ccctccagta gcacttttag agggaacaac cgctgtctct ggctgtttat
    38101 agctatatgc tgttttttta gcgaatacag gcgttttttt aggcgtagga cgcatgcctt
    38161 cgatttccag taactcctga tcgatttctt ctacaaaacg agaaggtcgg ttatattgcg
    38221 tccgtccata taatgttctg gagaaagcat ttgttaaata caacgcttct tctgctcgcg
    38281 tgatccccac atatgcgaga cggcgttctt cctccagttc gctttcttcc atcaatgctc
    38341 gagataaagg aaaaaccccc tcttctagac caatcaggaa tacaactgga aattctaatc
    38401 ctttggctgc atgcaaagtc atcaatgtca cttgggaagc atcttcttct aaattgtcaa
    38461 tgtcggaaac aagtgccaga tcatttaaga agaccgttag tttttcttct ggtgcatcag
    38521 cgtcttcttc attttgctgt tcgaattgtt tgtcgaattc ttgtgtgacc gttaaaaatt
    38581 cctccaagtt ttcgatgcgt gcttgtgctt ctaatgtatt ttggattttt aagtcttcta
    38641 gatatccgct acgatccaaa acctctttcg tcaattctgt cactgtcaag tatgggatca
    38701 tctgagtgac ttcttggatc atctctccaa atgcacctaa ttgctgtcct gcttttccac
    38761 cgatatttgc cagatccaca ttttgcgctg cttcaagcag tggccattca tgaagagaag
    38821 caaaactgcg tagtttttcg atagatcctg gtccgatgcc tcgtttgggc gaattaacga
    38881 tacgctcaaa actgattgaa tcttgaggat ttaccagcac attcaaatac gctaaaatat
    38941 ctttgatttc tttacgatcg tagaacttgt gccctccaac cattttataa ggaatatttg
    39001 ctttcaacag agtttcttcc attacacgag attgtgcgtt cgtccggtac aagatggcaa
    39061 agtcgccgta attccgatga ttgcttcgaa tctcttcttg catccggtct acgataaaac
    39121 gggtttcgtc tcgttcatta tctgcacggt agtaagtgat cttgtttcct tctttgtttt
    39181 ctgtccacaa gttttttggt tttcgattgc tattgttttc aatgacttgg tttgctgcgc
    39241 taaggatgtt tttcgtggag cgatagtttt gttctagcaa aattactgca gcatctggat
    39301 aatctttttc aaaatccaag atgttctgca tatctgcacc gcgccagccg taaatacttt
    39361 gatctgcatc tcccacgacg cacaggttcc taaatctacc tgccaataaa ttgactagcg
    39421 tatactgtgc gtgatttgta tcttggtact catctacatg aatataatgg aatttgtttt
    39481 gataatacgt gagtgaatca ggatgttctt caaataatcg aatcgtattc atgatcaggt
    39541 cgtcaaagtc catacattga ttatattgaa gctctttttg gtaagcagca taacattttg
    39601 ccgcaatctc ttcgtaataa ctgccttgca tttttgcaaa atcctgaggg gtctgcaggc
    39661 tgttttttgc ttgagagatt gttcctaata tacttcgagg atcatatttt ttcggatcaa
    39721 tgttcagttc ttttagtatc cgtttcatca aggtcagctg ttcagaagaa tcgatgattg
    39781 taaagttccg gttatacccg ataaaatcaa catctcttct taaaatacgc acacacatcg
    39841 agtgaaaagt cgatacccag acatcttcgc ctccagatgc gagaatcgca ttgacacgtt
    39901 ctttcatttc ttttgcagcc ttattggtaa aagtaatcgc taggatgttc caaggattga
    39961 cttctttttc ctcaatcaaa taggcaatgc ggtgtgtcag cactctcgtc tttccacttc
    40021 ctgcacctgc cattagcagt aatggtccgt cagtgtgaag aacagcttct ttctgacggg
    40081 ggttcatccc gtttaataat tcagctttgg atgacattaa caacatcctt tcttttatca
    40141 atcttgttaa ttatagcatt ttcttggctt tcattaaact agctagttca aaatcatttg
    40201 tttcttttta tggatttttc cttgtcaatt cgttgatttc gcgctaaatt aaaagaaagc
    40261 gaggcgtttg aatggaaaaa aaaggaaaaa tcaagaaatt agataagact cagatatatt
    40321 ttattctaaa aggaatattt gttggactgc tgacaggaat cgtcgttagc ctgtttcgat
    40381 tatctatcga aaagctaagc gatttagttc gaagtatcta tgaaatgagt cgggaacagc
    40441 cgatttactt aattggccta gctatttgct gcatccttgc agcatttttc gtgggttatc
    40501 tggtcaaaaa tgaaccggat atcaagggaa gcgggattcc acaagtagtg ggacagcttc
    40561 gcggggaatt atcaatgaac tggttctctg ttttatggaa aaagttcatt ggcggtgtac
    40621 tttcagttgg tgcgggcctt tttctaggta gagaaggacc ttctatacag cttggcgcat
    40681 ccattggaca aggagctgga caattgtttc ggagtccatc ttcagaagaa aagattttaa
    40741 tttctagcgg tgcaagtagc ggacttgcag cagcattcaa tgctcctatc gcaggattac
    40801 tctttgtttt agaagaaatc catcactcct tttctccact tgtttggctg acatcatttg
    40861 cttcagcaat cactgctaac ttcgtctctc tttacttttt cggcttgaga cctgttttat
    40921 atctaggtga ccttccttct ttgccgttga aatattatgg ttccttagtg atcttaggag
    40981 tacttctagg catcttaggt tttatttatc agaatgtctt gctggctttg ccaaaatttt
    41041 acaaccgatt gcctttacca gcttattttc acgggttcgt tcctttcttg ctgattttgc
    41101 caattggtta tttatggcct agtactctag gcggaggcaa tcaaatcgtt ttagcttttg
    41161 gacatgcttc cttgccaatc attatgatta tcggtttgtt tgttcttcga ttcgtttttt
    41221 ccatgatttc ttacggtggg ggtcttccag gggggatttt ccttccgata ttgacattgg
    41281 gggctttaat cggtagcttt tatggaaaca ttatggttga tttcgggatg gatccaatct
    41341 acatcaagga ttttgtcgtt attgccatgg ctggttattt cacagcgatt ggaaaagcac
    41401 cgctgacagc aattatttta gtgacagaaa tggttggctc tcttaatcat ctgatgcctt
    41461 taggattggc tgctcttgtt gcttatatcg tcaatgacct tctcggcggt aatccaattt
    41521 acgaatcatt attggaacgt ctacttggaa atactcagac cgcctcacta aaaggtgcaa
    41581 ggacaacttt tgattttcca gtaacggcag agagttcttt agacggatta atggtacgag
    41641 acttcaattg gcctaaaaat atgctgctaa tctctatacg cagaggaaat caggaaatct
    41701 tgactcacgg tgatacgatc atgaatgtag gagatatttt ggttatcttg actgatgaag
    41761 caaacttgcc aagaatcaag caggaaatcg aggctaaatc ttctatcaca aatttgaagc
    41821 aatcatttta acgaacatgg aaaaactatt ttacaacaac tattcatcta cactacttga
    41881 ttctatatga ttctataaaa aaagaagagg ctgggaaaac ccagcctctt cttttttatt
    41941 tctatgcttc tgctactgca ggagcttttc tcaataaacc ataaatcaca ccagatacga
    42001 ctgctccgat agcaataaac accaaataca tgaccgggtg actcagtaag aatacaacga
    42061 aaatcccgcc gtgaggagcc agtaatttga ttccgaaagc tccgactaat ccgccagtta
    42121 aagcagaacc aataataaaa cttggaatgg cacgaatcgg gtcagctgct gcaaatggaa
    42181 tcgatccttc cgtgacaaac gatagtccca tcacgatgtt cgtcaaacca gcatcttgat
    42241 ctgttttgct gaatttattc ttaaacaaac gtgtagcaac gaaaattgcc aatggaggta
    42301 ccattcctcc agccataaca gaagccatca cgacacttcc gccagttgca acagtcgtag
    42361 ctaaagttgc tgtaccaaac acataagcgg ctttgttgat tggaccgcct aaatctgccg
    42421 ccatcattcc agctaataat gcaccaagta aagcagcatt cgaaccactc atacttgtca
    42481 agaaaccgtt caatgcatca ttgattgctt tcatagggac attgaccagc aacatcaaga
    42541 aaccagtaat cagtaagcca aacactggat aaaagaggat cgttttaatt ccatccaatg
    42601 attttggtaa gttcttgaat aatttacgta aaaatacgat gacataacca gctaagaatc
    42661 caccaatcag tgcacctaag aatcctgcac cgcctgtatt agctaatgca ccagcagcaa
    42721 atccaacgat caaaccaggg cggtcaccga tacttgaagc aataaatcct gctaataccg
    42781 gcagcatgaa accaaatgca gcttgtccga tttggttgaa ccagctagca gcttgattgt
    42841 aattccctag atttgataat tgatcatgtg gcacgccaat aaattggtcg atcatgaaag
    42901 aaagcgcaat agcgattcct ccaccaataa cgaaaggtaa catgtgtgat acgccgttca
    42961 tcaaatcttt gtaaattctt tgtccgatag taccatccgc atttccttct tctgaactgc
    43021 tttcttttcc atcaccatgg aatactggtg cagtaccact aagggctaga ttgatcaact
    43081 cttctggttt acggatacca tcactgacag gacgattgat cagttctttt ccgtcaaagc
    43141 gattcatctc tacttttttg tctgctgcaa cgattacacc ttctgcacgg gcgatgtctt
    43201 cagcagtcaa tcggtttttg attccttctg aaccgttcgt ttcgactttg atctccacac
    43261 ccatttcttt cgcttttttc ttcaaagcat cttctgccat gtaagtgtga gcgatccctg
    43321 ttggacaagc tgtaacggca acaacgaatt ttctttctgg atgagcagaa gcttctgcag
    43381 cttgtgtttc ttgttctgct ttttcttctg cttctttttg ctcttcagct gtttggaaca
    43441 agtcttggac ttcttctggt gtatttgctt cttttaattt tcctacgaaa tctgcatcaa
    43501 tcagcaatcg agatagtgct gctaatgctt gcaaatgtgt gtcgtttgcg ccttctggag
    43561 ctgcgatcat gaaaaacaga taagttggct gtccgtctaa ggcttcataa tctactcctt
    43621 tttggctttt tgcgaataaa actgttgctt ctttaactgc actgtttttc gcgtgaggca
    43681 tggcgattcc atcaccaaga cctgtagaag tttgtgcttc gcgggctaga attccttctt
    43741 tatatgtttc gatatcggaa atccggccgg catcaaacat tttttggacc atttcatcga
    43801 ttgcgccttt tttatcagtc gcttgcaaat ccatgatcat cgcttctttg accattaaat
    43861 ccttgatatt catgattatc ctccttgaaa ctaatcaatt tttgtgattt caacttctgg
    43921 cagcaactca tcaatcaatt cgcgagctgc caagtcatca gaaaaagctg ttgcgcttcc
    43981 gcaagcaact ccccatttaa aggcttcgat tggatctttc gtacggctgt aagccccaat
    44041 aaagccagca atcattgaat cccctgcacc tactgaattt ttcaatgggc gaactaatac
    44101 attcgtttta taagttcctt gttccgtgaa gagcaaagca ccgtctccag ccattgagat
    44161 cagcacattc tgtgcccctt cagctagtaa ttttttccca tacggaatga tttcttctac
    44221 agattggaag gttgtgttgt aaagctcagc taattcgtga ttgtttggtt tgatcaacaa
    44281 cggtttctta acaagtgcat tttttaggtc atcacctgtt gtatcaatca cgaaatctgc
    44341 acctttttct cgaatgatat caatcagttc ttgataaaat ccttttcgca ggctagctgg
    44401 cgcgcttcct gacaatacga cgatatctcc ttgtcctact gttcctaatg cttgcttcaa
    44461 ctcatcgatt tcttcatctg aaatagatgg gcctaagcca ttgatctcag tttcagtttc
    44521 tgattttagt ttgatattga ttcttgtatc ttcttttacg gttgtgaaca aagactggat
    44581 ttgttctttt tcaagccact tcgaaataaa ttcgccagtg aaccctccta aaaaccctag
    44641 tgctgtagat tgagaatcga tccgtttcaa aatacgggaa acattgatcc cttttcctcc
    44701 aggtaacttg aagtcttcct tcattcggtt caaatcgcct agttttaacc catctacgcg
    44761 tacgatataa tcaattgatg gattaagtgt tactgtgtaa atcattgtat tgcctcctta
    44821 attgttgtct tttcacggaa ttcattaacg aattctaatg gacaacgctc ggttatgatc
    44881 gtggctgctt ccaaaggtgc aacagaggtg aaggacaact ggttgaattt ggtatgatca
    44941 atcaatacaa atgtctcttc ggaatttttc atggctaaac gtttaacagc tgcctcttct
    45001 ggatccggag tcgtgaatcc ttgttcaaga tgggcaccgt tcattcccat aaatgcttta
    45061 ttaaaatgaa aattttttag ttgttctatc gcattagatc ctaaaacagc attagttgcc
    45121 agctttatcg ttccacctaa aataatggta gcaagctcca aatcaactaa atttgccgca
    45181 tgttgaacgg aatttgtcac tactgtgatc tgttttcctt gcagaaaagg aatcatttct
    45241 aacgtagtag agccagcgtc taaataaatg acatcttcgt cattaatggt ttcagctgcc
    45301 gatttggcga tttgctgttt ttcgtgaacg tttttgagtg atttttcact catattctgc
    45361 tcaaaattca ataattgctc tttcttagct ccgccatgaa ctctttctag aaacccacta
    45421 ttctccagct cttgtaaatc acgtcttatc gttgattcag aagcattcaa aaggtttaca
    45481 agatcttgtg atttcacgat tttctgctgt tcaagcaagt ctaggatttt ttgtctgcgt
    45541 tcctctgtaa gcattttcac gatcacctca atacaaataa tagcatattt tttttctact
    45601 agcaatataa atcagtcaaa aacgttcata aaaattataa atcagtcaaa aaaaaataaa
    45661 aaaccagtca gaaagactgg ttttttattt ttttgtctat catcaagccg ttttatcgtt
    45721 ttttattttc gcttcttgtt tttttcatat aaacagaagc aggttttctt tccttatgaa
    45781 gaagataata ataaagtccc atcccgccaa acatgaccaa aaaaccgatg actgatcgaa
    45841 taggaaaatt aggaacaaaa aagagacaga cggataataa tgatgccgga accattattc
    45901 gataatagag ttgtttatcc attttcttca cctcatattt tttgtaaagt aatcaattgt
    45961 tctaattctc ggtaatctaa aaattgcaca cgcagatgct gctcaccttt cttgacatcg
    46021 aattggatac ttcgccgctt tttctttatt cgtttgaagg taacatcaga gagtctatgt
    46081 ttgatttcct ttaacggtaa ttctgacagg gattctgaag gaacatagat tcttaaggat
    46141 aaaagatact cttgatattt ttcatctgtt acctctactt ctagatattc cctaatataa
    46201 taacaataag cttcgattcc attatccaaa gcaacagtcg gatcgataac tttatagcac
    46261 atcatgcgtg atcgattctc gtcaacccaa ggaaaatacg cctgagcatt tagtgttccg
    46321 cgaacacgcc tttctttata atctccttgt tggatatcat aactttttgt tacaaaaaat
    46381 gaagcattct ttttaggaac aggttgcatt tgtgcattct gatactggac agattggatc
    46441 gtatggtcag tgtaaatgta ttcaacgaat ggcggtttca ataaaccgac accattgtcc
    46501 caagcaagat gatcaaaccc aagctggtcc ctaaaatagg attgaaacat ttgattgttt
    46561 ggcttttgcc agttaaaggg gtctcgataa agctggatac atatgacttc gttttctaat
    46621 tccttcactt tttctacttg ttggatgtcg agaaaaatcg gtttagggat gatttgatga
    46681 taatagcgac tataatacat ttcccaacac gaagtgaaac ataaaccttg gtaaaaaaga
    46741 tcgtatcctg gaaattggtt gcaatcgact actacttccc cgttttgttg tttcatttta
    46801 ggtaaatgtt cgatttcatc ctttttctca aacaatagcc gttgagagat ctgttttgta
    46861 ttgtgataga taaactcgct ataagctcgc atataggcga acaccccatg agcaatcatt
    46921 tttttctgaa tgaagtctcg aatcaaaaat tgcttttctt tgaaaacaga gatagacaat
    46981 acatttttta tcaataattg attatcttcc aagcgaaaac tacattcgtt ctcgtcattt
    47041 cctacaacta accaactttc gtctcttacc gatgctagca ttattttttc ttgaagcttt
    47101 cgaagatcat acggatccgc ttgttgtgtg aaagagcgga taaatgttgg ctggatcaac
    47161 agacgtgtca aaatagccca atcgcttatt tcctgttttt tttcttcttc atttaagtct
    47221 gtgagctgga tagtcatcaa taatttatct tcgccaatca ttttctcacc tctttcaaat
    47281 ctttttataa tttaattata accaatgata aagaaaaact aaaactttat gtcttagaaa
    47341 ccaatttgga cgattacatg atagactaag taaaaagaaa caaagaggtg tttacaatgg
    47401 ggttgaaatt tgaacgtaca gataatttag ataaactttt cgaatcattt gctgtcgatc
    47461 cggaaaaaac agttgcacca aaagaagaga tcgatcgatt tctaaaacca cagccacaaa
    47521 atgaaaagaa aaaagacaag aaacaaaagt aagttaagct caaaaaaaga cttaccagcc
    47581 aaacttttat gaaagagttt gactggtaag tcttttttat tctttttatg attcaattgc
    47641 ttgttcgatt gctgcccacg cttcttcttt tccctgtttt gtaacggaag aaaagagaat
    47701 aaacgtgtca ttgcgatcaa aatccaacgc ttttttgatt tcgctctcat gcttgttcca
    47761 tttaccacga gggatcttat ctgccttagt ggcaacaaca attacaggga tatcataata
    47821 cttcaaaaat tgatacatct ggatatcttc ttgagaaggc ttatgacgca aatctactaa
    47881 agaaacgacc gcacgtagct ggtctctagt cgttaaatat gtctcgatca tctttcccca
    47941 ttttgctcgc tcagttttgg atacttttgc atacccatat cccggaacat cgacaaaatg
    48001 taatgcgttc tcgatcaaat aaaaattcaa tgtctgggtc tttcctggct taccggaagt
    48061 acgggctaaa ttctttcgat caatcaatgt gttgataaaa gaagatttcc ctacatttga
    48121 tcgtcctgcc agagctattt ctggcaattg tgtatctgga tattgttttg gtgccactgc
    48181 acttatgata atttcagctt gatggacttt catggtctct ctccttaaca aggtgatgaa
    48241 taaagcaagc ggctgtcgca aaagccaaaa tgacttttac ggcagcctct tttcatcaac
    48301 ccgctttttt ctctgaatct ttatagatta ctgttggctc accagacaat tcagctgctt
    48361 cttttgtgat aatcactttt tcgatgtttt catttgaagg gatatcaaac atcacatcca
    48421 tcatgatttc ttcaatgatg gaacgaagtc ctcgagcacc ggtattgcgt tcgattgctt
    48481 ttttcgcaat ggctctcaac gcttcaggtt cgaattcaag ttcggtatta tctagagaaa
    48541 gaagtttttg atattgtttg actagcgcat ttttcggctc agtcaagatc cgtaccagat
    48601 catctgttgt caatttctct aaagctgcca taacaggtaa tcgtccgata aactcaggga
    48661 tcaatccgaa ttttagtaaa tcttcaggaa tgatatgctg catgacactt tcgtcttcag
    48721 aaagtttttg gttttgtgta ccaaatccaa tcgtcttttc gcccatacga ttcttcacaa
    48781 tcgtttcgat gccatcaaat gcaccaccta cgatgaacaa tatgttcgtc gtatcaatct
    48841 gaataaattc ttgatgtgga tgtttacgtc cgccctgagg tggcacactt gcaacagttc
    48901 cttctagaat tttcagcaag gcttgttgga caccttcgcc ggaaacgtca cgagtaatag
    48961 atacattttc gcttttacgc gcaattttat cgatctcatc aatatagatg atcccttttt
    49021 ctgcaagttc cacattgtaa tcagcagatt gaagcaattt aagcaaaatg ttttctacat
    49081 cttcccccac ataaccagct tctgtcaaac ttgtcgcatc tgcgattgca aaaggtacat
    49141 tcaatgtttt tgctaatgtt tgtgctaaaa atgttttacc agaccctgta ggtccgatca
    49201 agcagatatt gcttttttgc agttcaacat catctgtgtt ttcttgtgct tgctgattga
    49261 cacgtttata gtgattgtat acggcaacag ctaacgagcg ttttgcgcga tcttgtccaa
    49321 tcacgtagtt attcaatact tcaagaattt ctagtggttt agggacttca gtgaattcgc
    49381 gtacagcttc ttcataaaat tcttcatcaa tgatttcttt acataggtcg atacattcat
    49441 tacagatgta gacccctgga ccagctacga tctttttcac ttcttcttgg gttttcccgc
    49501 aaaaagaaca gcgtacggtc tcattgctac ttggattgtc atacatggtc ttcacccctt
    49561 aacttgcaaa aagtatgcaa gaaactatca aagactttac agtcttttac tatcataaca
    49621 tagtttagta aaaagaaaaa gtgtttaaca aaggatcaac tgacctatac ctttgcattt
    49681 tttactctta acaaaaaata aggaactgtg acaaaatcgt gtcacagtcc cttatttcga
    49741 ataaacaatt ttctagaagt agcttcttca gaaatgattt attacttgat ttctattctt
    49801 tcgcttctgt cgctgtacct gtgatcaatt cgattgcttt tttcattgtc acatcatgtt
    49861 ccagcatatc ttctgtcaac acgcgtttga tttgttcgat tggcatgttg tatgtttctg
    49921 ataattcttg gatttctgca ttgatttctt cttctgttgc ttgaagattt tcagcagctg
    49981 caattgcttc gatcacaaga tttgttcttg tgcgcatttc tgcttcacct tcgaattgtt
    50041 tatgcaagtc ttcttctgta gaaccagtta attgatagta catttcagga gagatacctt
    50101 gacgttgcat gttgttcaag aattcgtcca ttgaacgatg tacttcatca tgaaccatca
    50161 cgtgtggcaa ttcaacgatt tctgcgtttt caacagccat acggatcgct gcttcatctt
    50221 ttgcatcgtc cgctgctttt tcttttgttt ctactaattc tttgcgatat ttttctttca
    50281 attcgtctaa tgttgatact tcgtcatcaa catcttttgc gaattcgtca tctaattcag
    50341 gcacttcttt tgcttttact tcatggattg tcactttgaa gactgcttct tttccagcaa
    50401 gatcttctgc ttgataatct tctgggaaag ttacatttac atctagactt tcacctgatt
    50461 tatgaccaac taattgatct tcaaaacctg gaatgaatga gcctgaacct aattcaagtg
    50521 agtaattttc gccttttccg ccatcaaacg cttcgccatc tacaaagcct tcgaagtcga
    50581 ttactactgt atcgccattt tcagctgcag catcttcttt gataactaat tcagcttgtg
    50641 cttcttgttc acgtttgata cgtgcatcca cgtcagcatc tgttacttca cggtcttgtt
    50701 tttcaacaac tagatcttta tattgtccta attttacttc tggtttcact gttacttcag
    50761 cagtgattac ccagtcttga cctttttcca tgctttcaac atcgattttt ggttgagaaa
    50821 caggatcgat gccagcttct ttgacagcag cttcataagc ttctggtaat acagcattca
    50881 atgcatcttc atataaagct tcttcaccgt acatacggtt gaatacttga cgagaaactt
    50941 tccctttacg gaatccaggt acgttcaagc tttttttcac tttattaaac gcagttgtta
    51001 atcctttttg gatttcgtct tgcgcaatcg taaattttaa aacaccatca ttcgtgcctt
    51061 ttttttcaaa tgttgcagtc atttaattcc ctccgagttt agaaattcat tttatacatc
    51121 aaaaacgttt catgcatacc tttaaatagt acactaaccc tttcaaattg taaacatatt
    51181 gaatggatag aatccttgtt tttcataaca tttttatctt tttcactgat aaaatctaat
    51241 ggaagaagat catttgctgc aaaatttttt ctcttttttt taaaaaatct tgtttttcat
    51301 cttctgtacc ttcatacatc gtttttcctg tacacgcctc tacagtcagt tgaaaccagc
    51361 gcttcgggtc ttcgatgtat gtatcataga caggataaac aattgcagat tgcaacgtga
    51421 attcttcttt taacacggaa ctaagcagcg catcttcatt cccgtaacga tctgaaaata
    51481 cacataattg ctggtaactt gcctgctgct gcggctttgg cagatctttt ggtatgactt
    51541 tgactaactt ttcttcaatc gtcaaataga aaacaggatg gcattcgttc aattgcctaa
    51601 gtgtctccag taattttgcc cttgctaaaa tatggacctc tggcgataca ataagtttac
    51661 tcgctgtttg gataaactca tgataaggaa gctgttcgat ctcatcaata gacgcaagct
    51721 gacgtgcagg ttccaacgaa ggaagttcct ccgatttatt gtggagtgcc ttgatcttct
    51781 gcctctccat ttgtccggat aattcttctg caaattggat tttttcaatg acccgctgct
    51841 cgaaagcttc ataaaaatct gtacttgcta tcaattttct agcatataaa aaatcttgtg
    51901 tactgattaa caagtcaaaa taaaattcag caaactcctc attttgaaga tactgttttt
    51961 catgcaagag tgcttgcttc aatgcttctt ttttctcgtc caactcgtaa agacaaaaaa
    52021 caagcaggct attagcctca aagctttctt tcaactcgta agctcgttga aataattctt
    52081 ttgcctgctg atattgctgg tttgctagtg cttgttgtgc cactcgcatt aaattctcat
    52141 atttttctgg aaaatcaatc ggcttcacgc agtgtcctcc tcttgctcat attcagctca
    52201 tgttcaatag tagcaaaaca aaaaaagcat gacaattaaa aataactgaa gcaccctcta
    52261 aaagctagat tttagatctg acttttagaa ggtgctttca actgttactg ctttttattg
    52321 ctcatcagct gttgacttcc tggttgaacg ctttgatcag attgatcgta acaacacttg
    52381 tattagtgaa aaaatcgccc agatgttgct ttttctgatt aaagactgct ggaagatacc
    52441 ctaacatcag caaaggaaat tttagaatga accggcaagc accttctcta actaaaacgg
    52501 ttgaccagct aagttcttct tcatcaaagc tgatgactcg aataccaaag atcattttcc
    52561 caatcgtttg gccatgattg aatttcgtca ataaaataaa atacgctaga taaataagta
    52621 aggctgtgaa tccgtagaga ctcagataag aatctgaaaa attaagccaa cctagatttt
    52681 tggcaatacc aagtgttaaa cgcgtaatag ctccgataca caaaagatcg accaagaagg
    52741 caaacattcg gataaaaaaa cctgcataga aatacttagg aaaatcattt gcttttggcg
    52801 gttcatttct tgtgtccgta tactttttcc atttacgttg tttctttttg atttcttcgg
    52861 gcgtcaaagg ctctctttca aaagagctca gtaccttttg ggaaaagttg gagtcaggtc
    52921 ctacagcagg ctgctgttgc ttatcttttt cttgttcctt attttcattt gaaagctctg
    52981 acatgcttac tcacctccgt aataatacat tgcttttggt gattccgctg tccctagatt
    53041 ctcaagaacg gataagatct gactagtctc agaaggcttc aatccctgga attctgctag
    53101 tttacttcct aaccatgtac tagcaaaccc agatggcgtg gaagaatatt ctactagttc
    53161 cgcatcttca agctgttgtt cctttcgtat agcttttaaa gcatcttcag gaaatcccaa
    53221 ttcatcgact aaacctactt cttttgcttg gacaccatca taaatccttc catcagcaat
    53281 ttttttgact tcttcttcag atttattccg tccctcgctg acgattgcta caaaacgact
    53341 atatgcgctg tcgatatatg cttgaagcac cgcttcttct tcttttgtct ctggtcgcgt
    53401 tcctgaaccc atatctttca acgctccgct tttaactgtt gtatcttcca cacccagttt
    53461 ttctagaagt cctgaataat tcaatcctga catgatcaca ccaattgagc cggtcactgt
    53521 ttcttctgtt gcaaagattt tatctgcttg agcagaaata tagtagccac cgctagctgc
    53581 catgtttttc atgctgacat acattgggat atcatgttct ttacgaatcg tatccaattt
    53641 cttagcgatt tccgcacttt cgtagacacc gccaccagga gaatttactt ctaaaaagat
    53701 acctttgact gttggatctt cttcaatcgc cttcagttgt tccataaaat ttttatgatt
    53761 gtaaccttca gaagcaaata aacctgaaga ccctcccgca gcaatcgttc catctactga
    53821 taattttacg attttttgcg tactgtctcc ctcttccaac acatttggag ctagttcttc
    53881 atccccatat aaccaactgt tcaatccctc aatttgatcg ttttcctgag gcttagtcaa
    53941 actagctgaa actaacgaaa ccacaaataa tcctgcagca atcagaactg ctgcccaacg
    54001 tcttttattc attctttctc ctttctaata caagtttttt atgacgatca cagtttctga
    54061 ctgctcagaa gtgtcgaacc gctctgcttt ttcttcccgc gcatacccgg aaaacgactc
    54121 ttttgttaat tcatcttcta ccgtaaactc acgagcttga gcaacttcca aggcatcagg
    54181 tgcgatttct tggatgctat cccagccagt atctaaaaat attttcgtat catctgatac
    54241 accagctgat gcttcgaatt tggacaattg tttttttaac attcccagtg tcatgatctc
    54301 aatttttgaa tccattttta ctcctcctct atccgattac tttctattgt accgaactcc
    54361 tgaaaaagat gatagataaa aacccattat tttttgacat aaaaaggaca tttgacaaag
    54421 aatttgatat ataccaattt attttttatt ctttttttgt tgacaagaac attcgcaaaa
    54481 ggttatgatt ttaaatgttt ccagataaaa aacaaaaagg aggatagtta taccttttag
    54541 gatagcgcca ggtctgtgta aacagatgac gaggagaggg tttatcgaaa gattcggcgg
    54601 atggccctag ggactgcact ctacagaaaa tccacaaaaa atgtctgcaa agataaaaca
    54661 aaaggatttt cctgcagctg gaagcattca tacgaattca ttatagaaag taggatgttt
    54721 tttatgtgcg gaattgttgg aatgattgga ttaaaaaatg taacaccagg attgattgac
    54781 ggtctagaaa aattagaata ccgtggttat gattcagctg gtatctttgt ctcagatggc
    54841 acaactgatt atctggtcaa agcacaaggc agaattcaaa atttgaaaaa caaaataaat
    54901 attgatacta caggaaatat aggtattggt catacacgat gggcaactca cgggcaacct
    54961 tctgaagaaa acgcccatcc acatacttcc caaagtggac gcttcgtgct cgttcacaac
    55021 ggcgtaatcg aaaactttga agaacttaaa attgcttatt tagcaaatga ccactttatt
    55081 ggtgagaccg atactgagat tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca
    55141 acgcaagagg cgtttttaaa agctttgcgg gtcatcaaag gttcttacgc tttcgctttg
    55201 attgatcgga cagcacctga tgttatttac gtcgctaaaa ataaaagtcc actattaatc
    55261 ggactcggcg atggattcaa tgtgattgcc agcgatgcaa tggctatgct tgctcatacg
    55321 aaggaattcg ttgagattga agatgaagag atggttaccg tcacatcaga aaaagttatt
    55381 attcaaaatt ttgcaggtga catcgtagaa cgttcttcat tcgaagcaca agtagatgct
    55441 tcagatatcg agaaaggtac ctatcctttt tatatgctga aagaaatcga cgaacagcct
    55501 attatcatgc gtcgtatcgc tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat
    55561 caaaagctgg tcgatacatt gtctgatagc gatcgaatct atatcgttgc ttgcggaact
    55621 agttaccatg cggggttagc aggtaaacag actttggaaa aattgacaca gattcctgtt
    55681 gaggttcatt tagccagtga atttggctat aacacacctc ttctttcaaa aaaaccattc
    55741 tttattttct tgagtcaaag tggcgaaaca gcagacagcc gccaagtgct ggtaaaaatc
    55801 aaccgtctcg gctacccttc acttacgatt acaaatgttg ctggttctac tctttcgcgg
    55861 gaagcatcct ttacactgct attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa
    55921 gcttatactg cacaaatagc tgtactaact ttattagcca aagctatcgg tgataaaaaa
    55981 gaatttgaaa cttctcttgt attcgatatc actcatgaat tgagtttagt tgctaatgcg
    56041 atggaatcgg tcatcgccca aaaagattat ttagaagagt tggcagaagt atatctcagc
    56101 gatacaagaa atgcctttta cattggacgt ggtgctgact acaacgtttc tcttgaagct
    56161 gctttgaaat tgaaagaaat cagttatatc caggcagaag gttttgccgc tggcgaattg
    56221 aaacatggaa cgattgcttt gatcgaagaa ggaacaccag tgatcggaat catcagtgaa
    56281 gaagtgactg gtgcgcatac tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa
    56341 acactagtta ttgtctcaga gggattagaa aaggaaagtg accagctggt gctaccaact
    56401 gtccaccctt atctaactac tctaaccaca gtcgtaccga ctcaattact tgcatattac
    56461 gcaacgctat tacggggatt cgacgttgac aaaccacgta atttagcgaa atcagtgaca
    56521 gtagaataat aaaagaacaa ggaccagtgt cagacatctg acactggtcc ttgttctttt
    56581 attttttatg aaaatatctc ttaatccagt ccgatttctt ctttgactac tgccgcgatt
    56641 ttatcgacat agtaattaac tttctcatca gtaggcgctt ctgccatcac tcgaagtaat
    56701 ggttctgtac cggaaggacg aactaggatt cttccttctg atcccatttc agcttctgcc
    56761 tcttcaatca cttttttgat tgccggaaca tccatcgcac cgtttttatc acttacgcgg
    56821 atattcacta atttttgcgg atagattgtt acctctgctg caagctctga taatttctta
    56881 cctgtctgtt tcatgatatt cagtaactga attcctgaaa gcatcccatc tccagttgtg
    56941 ttaaaatcta agaaaatcat gtgcccagac tgctcgccgc caaagttata atcgtttttg
    57001 cgcatttctt ctacaacgta acgatcacca acttgtgtaa cgacatcttt caaaccgatt
    57061 ccttccaccg ctttgtggaa tcctaagtta ctcatgacag tcgtaacgat cgtatctttt
    57121 ttcaatcgat ttttttctgc caagtattta gcacagataa acatgatttt atcaccgtcg
    57181 acaatgtttc caagttcatc caccgcaata atacgatcgc catcgccatc gaaagctagt
    57241 ccagcatctg ctcctttttc aacgaccatc tcagctaaac gttctggatg ggtagagcct
    57301 acgccgtcat tgatatttaa cccgtctgga tttgtgccca ttgtataaaa atctgtttca
    57361 agatcggcaa acaaacgatt aacacttgtt gaagttgctc cgtttgctgc atcgacacaa
    57421 atggtcaaac cggaaaggtc accgttgatc gtttgtacaa ggaattgaga atatttcaat
    57481 aagccttctg gaaattcttc tacagttccc aatccttcag ctgatggacg aggcaattca
    57541 tccacttcag catctaataa tgcttcaatt tctagctctt ggtcatctac tagtttaaaa
    57601 ccatctgcac cgaaaaattt gattccatta tcttgtgctg gattatgaga agcagaaatc
    57661 atgacccctg cgcttgcttt ttgcaaacgt gtcagataag caacacctgg tgtagagatc
    57721 acacctagct ggaacacttc gatacccacc gataaaagtc ctgaaatcag cgcttcttct
    57781 aacatttgac ctgagattct tgtatcccgc cctactaaca cgcgtgggcg ttttccttct
    57841 tcttcatgct ggcttaggac ataacctccg caccgtccca gcttaaatgc aagttctggc
    57901 gtaagttcct tgttggcttc accgcgtacg ccgtctgttc caaaatattt acccatagtt
    57961 gtaaaattac tcctttaact taattttctg aggaatttgt tctgctcatt tgtgttgatt
    58021 cgcttgtttc tgatgtttct tctgtacttg tggtcgagct gcttgtccca gattccgaac
    58081 tggaagaaat ggttgttgtc gatggttccg ttcctgaatc agcagatgaa atacttctac
    58141 tcgtacttgt attttcttgt gtccgactgc tcgtcgaagc agagctactg cttgacgttt
    58201 gcaacacggg tgtaatctcc acactaactg attcgggctt gatacttaac ccctcttcta
    58261 ctggtatttc aattttacga gttgttcgat gattgatacc tgagacattg atcggtacag
    58321 caatactgtc accgatcgat gcaagcaaat cgctagagcc gcttacttct gcttccagtt
    58381 ttgaaaaact gaaatcatag ctttctaccc cggcagctgg tgttccttgc tgtatcccat
    58441 aaagtcgtac cgacttgctt ggcttgatcg aatcagctct cactgttact tgcactggat
    58501 cagagacgat acttaatact tcccctgctg cattcagcgc ctgtattggg acctcactat
    58561 taatcccatc atctgtgacc atcgaagcgt ccacatcagc tactactcgt ttgatttctg
    58621 ccaatgtttt gtcacctgta gtgatagaga cttttttagg actaacggaa gtatcatcaa
    58681 gttcatatcc agatggtgtg aacgttgaag gaatcaacgt ttccacatcg aaatctttta
    58741 ttaccttttt ctcaaccgtt actgtaatag tcgatggttc gatctttgct gtgacagcac
    58801 tgctcaaatt ttgaattttt agcggaactt catgtgttcc ttcgcccagc ttagtgatat
    58861 ctgctgtgac gcggaacatc cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt
    58921 ttgcactgga aagtttgaca gtcactgcat tttcatatcc atggatatag tagcgctttg
    58981 aatcataaga aatcttgatc ggcacccccg taactgtttg attatacgct tcatttccag
    59041 aaagcgtatt tggaacggac tggccatttg cattgaagta cagcgcaata ctgaacagca
    59101 atgcaataaa actgtaaaga atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc
    59161 tcccttagtc ataccgtcta ggaaagattg aatcacgttt ttcttgtttt ttgttttctc
    59221 ttcagcaatt agttctctac gcaagattgc caaatattct tgctgggata agccagccat
    59281 cagttcatta tctaacgtga tgctgacgtc cccggtttct tcagagacaa cgatggtaat
    59341 cgcgtcactg acttcgctta taccgacagc tgcccggtgt cgagtcccga attctttagg
    59401 gatcaacata ctttctgata gaggaagata ggcgcttgct actgcgatct ttccttcttt
    59461 tacaataact gcaccgtcat gcagcggtgt attaggaata aagatattga tcagcagctc
    59521 cccagtgata tctgcatcta aagcaatccc tgtctcaata tactcatcta atccagtatg
    59581 acgttcgata gtgatcaacg caccgatttt tcgcttggac atatattgga tggctttgtc
    59641 aaaagacaag atcatcttct catcttcctg ctgttcgctt tttgattgtt tgaaaagcga
    59701 actgcgtcca agatgttcca gtcctctccg gatttccggc tgaaaaatca cgatagcagc
    59761 tatcaccccg tacgtaatga cttggttcat cagccaagac aaggtgtgca gaccaatgat
    59821 ttccgctacg attcggataa caataaaaat agctacacct ttcagaagct gaatcgcttt
    59881 tgtgcctcgc agcagttgga tcagtttgta tacaagatac cagacaacca gaatatcaag
    59941 tatgttcacc aaaaaattca gagagaacaa gtcaccggaa aacatttgct gccaatagtc
    60001 caaattaaaa agttccccga tttgaaatga cataaaaagc ctctcttctc ttttgagatt
    60061 tcctctctag tatatcatat gttttaattt tagaggctga tatgctcgta tttttcttga
    60121 gaaaaacgca taattttcaa gaaaattgca agtatgcgtt ttatttttct ctgcaataaa
    60181 tatttttaaa cttcagagaa ttattcatta tattttttct gttatttttc ctttttttct
    60241 tttgtagctt gttccatttt tttacgtcgt tctgctctgg cagctcttct agcagctctt
    60301 ctttcttctg cttcaaggtc cgtcgttttt tcttttctag tcttaacggg tacatcgata
    60361 gattcctctg gttcaagtcg tttcttgatt ttttctaatt ctcccgtcag tgcagcatag
    60421 ttgtaaaaac gtgttttagc gtcgtggaca gtcttttcaa ataaagcttt tgcaagattt
    60481 ggatttgcgt tatctagcga ggaaaagcga acttgtttcc tcatgaaatc aggcatagca
    60541 gagaaatcag gttttttgta gtccaaagtc attgggttct tgtttttttc gaccattgta
    60601 gggttatatc gatataatga ccaataacca gaagaaacag cttcttttgc ttctttaagc
    60661 gattctttca ttccgccaag caagccatgt gtgatacaag gcgtataggc aataatcaga
    60721 gaaggaccag gatacttttc tgcttcttca aatgccttga tcgtttgcat ttgattggca
    60781 cctgaagcaa tttgcgccac ataaacattt ccatatgtca tcgccatcat tcctagatct
    60841 ttctttgaag catactttcc actagccgaa aatttagcga ttgccgaagc tggtgttgct
    60901 tttgaggttt gaccgccagt attggaatag acttcgttat ccaaaacaag gatattcacg
    60961 tctgctccgc tggcaagtac atgatcgatc ccgccaaaac caatgtcgta agcccatccg
    61021 tctccaccaa tcatccattg gctgtttttt acgaatagat cctttctctt gtatatatcc
    61081 tccagttcag ggaaaattga tcgttcgctt tcgatcgcag cttgcagttt tgctgctctt
    61141 tgctgcgttc cttcactctc aaacatgtgt actaaccagt cttccatcaa ttctcgtagt
    61201 tcttctgata cttttggcaa tacttctttg attgaacttg ccaaagcctc gcgacgagtc
    61261 tgtgccgcta gaagcatacc ataaccaaat tcagcattat cttccaataa agaatttgac
    61321 catgcaggcc cttgaccaca ttcattggtc gtataaggag aagcaggaga agcaccgccc
    61381 caaatagaag aacagcctgt cgcattcgcg atcatcattc gatcaccgaa catttgtgtc
    61441 aataatttta cataaggtgt ttcgccacag cctgagcaag cgcccgagaa ttcaagaagc
    61501 ggttgattga attgtgtaga caagacagta ttctttcctt tgactggatt tgctttttgt
    61561 cttaatgtca ttgcaaaagc ccaattcaca gcttgttctt tctgttcttc ataaggcttc
    61621 atcactaaag ctttttcttt tgcgggacaa gcctctacac acagaccaca acctgtacag
    61681 tcttccactg aaacttggat acggtatttt acgccgtctg cgcctcgcat ttctctcacg
    61741 ataaatcctt ctggcgcttc ttccatttcc tcttcatctg ctaaaaatgg acggatggca
    61801 gcatgaggac aaacaaaggc acattcatta cacatcgtac agcgatcact aatccactca
    61861 ggtacttcta aagcgacgcc ccgcttttcc atagaagccg ttcctaaagg catttcgcca
    61921 gttgtcattc catttgctac aagtgtacca acagagagtt gatttccttc ctgtgcattc
    61981 actggttcaa gtatttcttg tatataacca atgttccttt tattgatttt ttcaggcatc
    62041 tccaacgttc tccaatggtc tgggatcgcg acttgatgaa gcagttcggt cgtccgatcg
    62101 attgcttgta tgtttttttc tacgatagcc attgatttat gtccatagct tttcagggct
    62161 tcttctttta gcagcggaag cacctcatca aaaggaatga tgtcagctaa tttaaaaaaa
    62221 gccgtttcca ttgccgtatt gatccggcgt cccaaaccga cttcttgggc caatctcatg
    62281 gcattgatcg tatagaatct aatgttattt tcagccaagt aacgttttaa ttttaagggc
    62341 agatgcgttt ctaattgttc gtcgctccaa agagtattca ataaaaaaat gccacctggc
    62401 ttcaatcctt tgaccaagtc atagctatgc aggtaagctg gtgtgtgaca ggcaacaagg
    62461 tccgcatgct cgacaagata cgctgaacgt atcggcgtat ctccaaaacg aagatgagag
    62521 acagtcagac cgccagattt tttcgaatca taataaaaat agccttgcgc atatttatcg
    62581 gtgtgatctc caataatctt gatagctgat ttatttgctc caactgttcc gtcagatcca
    62641 aatccccaaa acttggcctg gaatgtttgc ggttctgtca aatccagact ttcctttggt
    62701 tccaaagatt gataagtcac atcatccacg atccctatgg taaaccgttt tttgcgtatg
    62761 cttgggtctt ttttcaattc atcaaaaact gctgagattt ggtcgggagt cacatcttta
    62821 gaccccaatc cgtagcgacc accaataaca gccgggcgaa gttcagaatc atataacgca
    62881 ctttgaacgt ctaataagag aggttctcca cctgcccctg gttctttact tcgatcaaga
    62941 acagcaattg tttttactgt atgaggcaac ttttgcacga atgtttccac tggaaaagga
    63001 cgataaagat ggatattcaa aaaacctgtt ttccgtccgt ttgcattcaa gtaatcaatc
    63061 gtttgttcaa tcgtctgtgc aactgatccc atagaaacaa tgacttcttc cgcatcgtct
    63121 gctccgtaat aagtcaccaa gtcataagaa gttcctcgta atcggttgat ctctttcata
    63181 tatttttgaa cgatttcagg taatttatca taataggggt tgatcgtttc ccgttgttga
    63241 aaatggatgt ctggattctg gttcgtacca ctaacagtcg gatgattggg attcatccct
    63301 cgtttacgaa atgaagctaa tttctcctga ttgatcagag gagctaattc ttcatattcc
    63361 aaaacttcga ttttttgaat ctcgtgactc gtacggaatc catcaaagaa attcaaaaaa
    63421 gggacttctc cttcaataga agcaagatgg gcaacaggtg ctaaatccat cacttcttgt
    63481 acactgcttt cagctaacat agcaaatcct gtttgtcttg cagccatcac gtctccgtga
    63541 tctccgaaaa tattcaacgc atttgtcgtc actgcccgac tagcaacgtg gaaaacactt
    63601 ggcagtagtt ccccagcaat cttgtacata ttcggtatca tcaaaagcag cccttgtgaa
    63661 gcggtatatg tagttgtcag tgcaccagtt ttcaatgatc catggaccac accagctgct
    63721 cctgcttcgg attgcatttc tactactttt actggttgac cgaatacgtt ttcttttcct
    63781 gctgctgacc attgatctac taattcagcc atggtcgaac tgggtgttat tggatatatt
    63841 gcagcaatct cggtaaatgc ataagaaata tatgcggctg ccgtattgcc atccattgtt
    63901 ttcatttttc gcatgattca tcatccttgt tcatattctc tcttattatc tgttccatta
    63961 taacgtaaaa catgccattt ttttctttta tttataaaaa tattttacat gtatctattt
    64021 gaattggtca tctaattttt agacaaacag tctaaatcgt tgcctttttt tgtcagacat
    64081 gtataaacta taagcgaaag aggtgtttta acatggatat atcagtgatt gatgcaacga
    64141 aaacaaatac acaaaaagga atcctttatg gttcatcgaa tgctcctaaa aaaatggtcg
    64201 aattcatcaa cttagcttgt ccgtattgcc gacaatggtt tgaagaatct tatgagctat
    64261 tagaagaagc agtccaaagc gggcaattgc agcgagtgat caaattgttc gataaagaaa
    64321 aagaaagctt acagcgaggg aacgtgatgc accggtatct cacaatcagc gatggccaaa
    64381 aagcgatcaa agagatcaaa caaatattcg atactcaaga cgagtggaaa catctttctc
    64441 tccaagaagt agcggatttt gcagtagata aactaaagct gacagaacaa aaagacgaac
    64501 agctgagcca agctgtcatc aacgaagctg agcaagcaca tattcgattt gttccaactg
    64561 tcatcttggg taaagaaatc tttgatgaat ctatttcaat agaggaatta aaagaattga
    64621 tccaaacaaa ataaaaaaat aaggagcgtg ggacaaaagt aaagaacact tttgtctcac
    64681 gctctaaaca cgtataaacg gcggaagcag aagcaactcc ttcttatttc ttggagttaa
    64741 acgcttctgt cccagcctcc ttattccgaa taaatggtgt ccaaaagctt gcatctgcca
    64801 gattatctca tttcttatga caagctaagc aaattatctc caccaaataa tttattcata
    64861 tttttgactt gcgcatacta actaattctt aaattttcat acaaaatttc tcaatttccc
    64921 ttaacgagta atatttatgt acggtgattc tcactagtat cccaatcact ttttaagtta
    64981 tcccgatttc aattctactt caaaaatagt tgcttttatg tatgctgtta gttgattaga
    65041 tggtcatttg ttgagctagg tcgtttattt taaacaagtt gtttctttag cttataccta
    65101 tctcgtctac caaacgcaag atggcaaaca caaatgcata cgcatctgta tttgccactt
    65161 tgattcgtat aaagctaaca actattaact cctctcagct aatagttgct ctctttttta
    65221 ttcagattca tttttgctga tcacagccta gtatttcaat ggttttgaac actaaaccaa
    65281 attgttccat tacaacattc actggctgat gaaatggatt agtagatttc gattattcaa
    65341 agcgattttc tattggtgga tcgtgttccc aactaataag acggattcca aacctatcgt
    65401 acagatcttc taaaccactt ataaattttg cacctatttc aggtgtttta ttgcgtggat
    65461 attctattgt tacgccatta aatggatacc aattaggatt aggctctctt tttttctgta
    65521 catctcccat agaatagtta gcactttctg ggacataata tattcttcga ccatcctcta
    65581 attcatctaa taagatattt cgtgatcgtc tatcacttgc taaatgtaga cgccacgtgc
    65641 gataccatgc catgctacct gcatctgcag aaaatccatc aaataatgca acaattgtat
    65701 cttctatcac aatcctttcc ccatctactt catattctaa tctaaaatca aactcccctc
    65761 gggtaatttc tggtcttggt ggcttaggac ccaatattat tctacttaaa accgcattcg
    65821 ttcccagatg aaacacagct ataacaacaa taatgattaa tattttgttt ctatttgata
    65881 aatttctcat tattcgcaca tcacctctac attctcacat attagttcgt aatactcctt
    65941 taatatcaaa atatctactg gtcgtaataa tattcgctat gaattcctac tactcgtata
    66001 agaaaggcca aatcatcagc ttttacttgc tgatgatttg gcttgtttct atttatcgta
    66061 attgttttct aatcaccaaa attgttaaca atcggttcag atatttccca gttgattaag
    66121 gtaattccgt attgtgtcaa aacttcttgc gcttctccga aattaagtac agttcttatg
    66181 tatccacttt ctcctaatat aaagtctacc tctcttttaa aaccttcctc gagatttcta
    66241 agggctatat gtggttttaa tgacattgat tgtacatttt cccccatata atattgcgca
    66301 cttcctcgac taaaatagat tcctagatcg tccccaaaag gtagatcttc tctaccacta
    66361 gctaatctac ttctccatct tcgttctctt ttcatagaac ctgcgctgaa ctcacacccg
    66421 ttaaactcag ctatgacagt atcttcaatt atgttaatct gtccatctag ttcgtattca
    66481 atcctaaatg gaaattctcc ataggtgatt tccggttcgg gtattttagg tgagattaat
    66541 gcaaagaaag gaaatattaa gcttggcaac atcaaaaaaa ctcctcctat gatcacaatt
    66601 cccgatgtaa tccaaaatat aatttgtaca attctcattg atccattgta ttccatttta
    66661 ttccccctat tactattcat atccgcctat ctatatcgat cttccaatgc agagataatt
    66721 gcttccatac cttgattttt tactgagtta cctatgcgag atatcattct ccactaaggt
    66781 gcatcatatt gtctatctaa catgattaat tctccaatag gtgtatactc ctccaaaaac
    66841 aacatttaat gcatctccct cgacaacata agctaccatg tttgctgtat atgtgtttga
    66901 gtctaattca taagcagata aatttactgt cgctggatta aatataatcg cattcgtatt
    66961 tatagctact gaatttgctg cttcagcacc accttttgaa tgtccgatca ttgtgatttc
    67021 aatagtagga tttacgtgga cagccctcac cgtttaccct gaccattata gaaatcgctt
    67081 acttttttga actacgcaac aaaggataca atgctcctaa cttcactgtc tccatttttg
    67141 tccactaagg aatataaaaa ataggcatta attcatttaa ttcggtcaca acacgttacc
    67201 ttttaaatca ttatactgta tctcatacat tattatcaat aaactattat aaaaatgcaa
    67261 aaaatgcttt atcaatctat tttgtaattg gtcataatat cattgaaatc ataccctgta
    67321 tcgatttttc ctatgaatct cgtctatttg tgattgacga aaaagaggca agacagacac
    67381 tggaatggta attttaccca ctattttgct ccaactattt gtaatcgtac ccacttttga
    67441 aataccgaga tgatcatttt aattgatatg ctgattccca agcaaaaccc caagaaatta
    67501 aatgctctat cgcatctagc ttcttgggtt ttgcttatat aaattccaac atttaaattt
    67561 tttatgctgt tcggtctcag aaatgccgtt tttgcttata tcacaatatc aagatgtcaa
    67621 attattcgtg ttgccgatga ctttgattat tttttttcaa attgtttatt aagactaatg
    67681 ctgtcttttt gcagatacca atgttcgaac tttttaacat tatcatatga tcctgcaagt
    67741 tttaacttct taccattaga tgttatcaaa gttataatta accttgcctt tttcccatta
    67801 ggatctttta ttttatgaat tttctgcagg taatctctcc taatggcagc tatttttacc
    67861 tcatcagtgc tgataaacca ttgatcatcc acatacatac tgcctgttat gttgtgtttt
    67921 tccatttctt ccgagaacga aaagtttaag gctcgttctt acttccaaag ttgaatgagt
    67981 ccatggattg gacttagtgt gagaattgag aacaacaata agaatccata tcctcccgca
    68041 aacatcccta aggctatact gtctctccat ccataagtag gattagaaga gaaaagagtc
    68101 accgtttgta ataatatgaa aaggaataat ccagcacaaa caccaaagat aacaactcca
    68161 aacattgaat ttttatacaa tgaccattta tttataggct tttctttcat tttacttccc
    68221 cctactgttc tgttcacacg gaatgaattc aaagttcata agccctcctc tttgaacata
    68281 tgaatacgac ttgctaacta tactttaaaa aagcttgttt taagcggtta taggcgagtt
    68341 gtaatctcta ttcatctcat tagcaaataa cttgccgaaa agtctactga aattaaagca
    68401 gatagtggaa gaattattta gccaggatag acactatttg tgaaacacat gtctttactt
    68461 ttgaaattct atgatgaaaa gccttggaat acagtagctc ttaattggta atactttttc
    68521 cattataaat aacctctttt cattttatat ttatcccctc taaaaataat atctaatcta
    68581 atattttaaa cttatatttc cctcgctgtg ctaatagagc attactaaat aaatagaaac
    68641 tagaaaaaag cattacgcct gccagaataa accaattatt tgt
//
LOCUS       DAFEEZ010000007        65811 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000007
VERSION     DAFEEZ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.007"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(60..404)
                     /locus_tag="LP245_000552"
     CDS             complement(60..404)
                     /locus_tag="LP245_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBL1518494.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(541..1686)
                     /locus_tag="LP245_000553"
     CDS             complement(541..1686)
                     /locus_tag="LP245_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL1518495.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(1866..2840)
                     /locus_tag="LP245_000554"
     CDS             complement(1866..2840)
                     /locus_tag="LP245_000554"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBL1518496.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(2920..3795)
                     /locus_tag="LP245_000555"
     CDS             complement(2920..3795)
                     /locus_tag="LP245_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBL1518497.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            3925..5832
                     /locus_tag="LP245_000556"
     CDS             3925..5832
                     /locus_tag="LP245_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBL1518498.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(6373..9651)
                     /locus_tag="LP245_000557"
     CDS             complement(6373..9651)
                     /locus_tag="LP245_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBL1518499.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(9922..10467)
                     /locus_tag="LP245_000558"
     CDS             complement(9922..10467)
                     /locus_tag="LP245_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1518500.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(10479..11171)
                     /locus_tag="LP245_000559"
     CDS             complement(10479..11171)
                     /locus_tag="LP245_000559"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBL1518501.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(11190..11474)
                     /locus_tag="LP245_000560"
     CDS             complement(11190..11474)
                     /locus_tag="LP245_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518502.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(11487..12050)
                     /locus_tag="LP245_000561"
     CDS             complement(11487..12050)
                     /locus_tag="LP245_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL1518503.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            12278..12940
                     /locus_tag="LP245_000562"
     CDS             12278..12940
                     /locus_tag="LP245_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBL1518504.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            13064..14260
                     /locus_tag="LP245_000563"
     CDS             13064..14260
                     /locus_tag="LP245_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBL1518505.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(14361..15737)
                     /locus_tag="LP245_000564"
     CDS             complement(14361..15737)
                     /locus_tag="LP245_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1518506.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(15774..16640)
                     /locus_tag="LP245_000565"
     CDS             complement(15774..16640)
                     /locus_tag="LP245_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HBL1518507.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(16729..17754)
                     /locus_tag="LP245_000566"
     CDS             complement(16729..17754)
                     /locus_tag="LP245_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL1518508.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(17829..18446)
                     /locus_tag="LP245_000567"
     CDS             complement(17829..18446)
                     /locus_tag="LP245_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1518509.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDNNLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIE"
     gene            complement(18630..19523)
                     /locus_tag="LP245_000568"
     CDS             complement(18630..19523)
                     /locus_tag="LP245_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1518510.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(19597..21294)
                     /locus_tag="LP245_000569"
     CDS             complement(19597..21294)
                     /locus_tag="LP245_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL1518511.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(21287..22600)
                     /locus_tag="LP245_000570"
     CDS             complement(21287..22600)
                     /locus_tag="LP245_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBL1518512.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(22600..26637)
                     /locus_tag="LP245_000571"
     CDS             complement(22600..26637)
                     /locus_tag="LP245_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL1518513.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(26650..27108)
                     /locus_tag="LP245_000572"
     CDS             complement(26650..27108)
                     /locus_tag="LP245_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1518514.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(27406..27924)
                     /locus_tag="LP245_000573"
     CDS             complement(27406..27924)
                     /locus_tag="LP245_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBL1518515.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(27926..28543)
                     /locus_tag="LP245_000574"
     CDS             complement(27926..28543)
                     /locus_tag="LP245_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBL1518516.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(28540..29403)
                     /locus_tag="LP245_000575"
     CDS             complement(28540..29403)
                     /locus_tag="LP245_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1518517.1"
                     /translation="MTANDGLFQKDQCESANKKILSYVLMTVIGIILIIPLLWMVFTS
                     LKPMEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFI
                     AYGFAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGN
                     AFNIFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWN
                     DFLGPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFI
                     EGMDLTGGSKG"
     gene            complement(29390..30292)
                     /locus_tag="LP245_000576"
     CDS             complement(29390..30292)
                     /locus_tag="LP245_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1518518.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAGYAMAMSMILFLI
                     VLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(30333..31667)
                     /locus_tag="LP245_000577"
     CDS             complement(30333..31667)
                     /locus_tag="LP245_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1518519.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKIFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            31875..32705
                     /locus_tag="LP245_000578"
     CDS             31875..32705
                     /locus_tag="LP245_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBL1518520.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(32949..33267)
                     /locus_tag="LP245_000579"
                     /pseudo
     CDS             complement(32949..33267)
                     /locus_tag="LP245_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(33389..33583)
                     /locus_tag="LP245_000580"
     CDS             complement(33389..33583)
                     /locus_tag="LP245_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518521.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(34088..34273)
                     /locus_tag="LP245_000581"
     CDS             complement(34088..34273)
                     /locus_tag="LP245_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518522.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(35123..35464)
                     /locus_tag="LP245_000582"
     CDS             complement(35123..35464)
                     /locus_tag="LP245_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL1518523.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(35464..35694)
                     /locus_tag="LP245_000583"
     CDS             complement(35464..35694)
                     /locus_tag="LP245_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1518524.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            35981..36319
                     /locus_tag="LP245_000584"
     CDS             35981..36319
                     /locus_tag="LP245_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518525.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(36524..36763)
                     /locus_tag="LP245_000585"
     CDS             complement(36524..36763)
                     /locus_tag="LP245_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBL1518526.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(36739..37086)
                     /locus_tag="LP245_000586"
     CDS             complement(36739..37086)
                     /locus_tag="LP245_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBL1518527.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(37818..38399)
                     /locus_tag="LP245_000587"
     CDS             complement(37818..38399)
                     /locus_tag="LP245_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1518528.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(38582..39208)
                     /locus_tag="LP245_000588"
     CDS             complement(38582..39208)
                     /locus_tag="LP245_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1518529.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(39230..40561)
                     /locus_tag="LP245_000589"
     CDS             complement(39230..40561)
                     /locus_tag="LP245_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBL1518530.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(40716..41117)
                     /locus_tag="LP245_000590"
     CDS             complement(40716..41117)
                     /locus_tag="LP245_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBL1518531.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(41203..41409)
                     /locus_tag="LP245_000591"
     CDS             complement(41203..41409)
                     /locus_tag="LP245_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518532.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(41504..43006)
                     /locus_tag="LP245_000592"
     CDS             complement(41504..43006)
                     /locus_tag="LP245_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBL1518533.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(43024..43479)
                     /gene="argR"
                     /locus_tag="LP245_000593"
     CDS             complement(43024..43479)
                     /gene="argR"
                     /locus_tag="LP245_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBL1518534.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(43577..44194)
                     /locus_tag="LP245_000594"
     CDS             complement(43577..44194)
                     /locus_tag="LP245_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBL1518535.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            44415..45788
                     /locus_tag="LP245_000595"
     CDS             44415..45788
                     /locus_tag="LP245_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1518536.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            45863..46975
                     /locus_tag="LP245_000596"
     CDS             45863..46975
                     /locus_tag="LP245_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBL1518537.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(47047..48684)
                     /locus_tag="LP245_000597"
     CDS             complement(47047..48684)
                     /locus_tag="LP245_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBL1518538.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(48852..49460)
                     /locus_tag="LP245_000598"
     CDS             complement(48852..49460)
                     /locus_tag="LP245_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1518539.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(49844..50995)
                     /gene="queG"
                     /locus_tag="LP245_000599"
     CDS             complement(49844..50995)
                     /gene="queG"
                     /locus_tag="LP245_000599"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBL1518540.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(51014..51766)
                     /locus_tag="LP245_000600"
     CDS             complement(51014..51766)
                     /locus_tag="LP245_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518541.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(51907..52857)
                     /locus_tag="LP245_000601"
                     /pseudo
     CDS             complement(51907..52857)
                     /locus_tag="LP245_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
     gene            complement(52858..53697)
                     /locus_tag="LP245_000602"
     CDS             complement(52858..53697)
                     /locus_tag="LP245_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL1518542.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(53694..54440)
                     /locus_tag="LP245_000603"
     CDS             complement(53694..54440)
                     /locus_tag="LP245_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL1518543.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            54678..56048
                     /locus_tag="LP245_000604"
     CDS             54678..56048
                     /locus_tag="LP245_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1518544.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(56103..56999)
                     /locus_tag="LP245_000605"
     CDS             complement(56103..56999)
                     /locus_tag="LP245_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1518545.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(57113..57283)
                     /locus_tag="LP245_000606"
     CDS             complement(57113..57283)
                     /locus_tag="LP245_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518546.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(57280..57957)
                     /locus_tag="LP245_000607"
     CDS             complement(57280..57957)
                     /locus_tag="LP245_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBL1518547.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(58048..58953)
                     /locus_tag="LP245_000608"
     CDS             complement(58048..58953)
                     /locus_tag="LP245_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL1518548.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLILVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            59128..60582
                     /locus_tag="LP245_000609"
     CDS             59128..60582
                     /locus_tag="LP245_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1518549.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            60598..61629
                     /locus_tag="LP245_000610"
     CDS             60598..61629
                     /locus_tag="LP245_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL1518550.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            61636..62823
                     /locus_tag="LP245_000611"
     CDS             61636..62823
                     /locus_tag="LP245_000611"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBL1518551.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            62979..64361
                     /locus_tag="LP245_000612"
     CDS             62979..64361
                     /locus_tag="LP245_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBL1518552.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            64488..64718
                     /locus_tag="LP245_000613"
     CDS             64488..64718
                     /locus_tag="LP245_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518553.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(64918..65586)
                     /locus_tag="LP245_000614"
     CDS             complement(64918..65586)
                     /locus_tag="LP245_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBL1518554.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        18864 a        13755 c        11729 g        21463 t
ORIGIN      
        1 aaagttagtc atctaacaat aggccgtttc aaaactagtt gtctttttat atccacagat
       61 cattcgactt tttcgaataa cccacggcta atcatcccat ccatcagaaa ataaaattta
      121 tcttggctca ttttctgttt tggatctttg aaaatattga ctgctttcaa tccatttgct
      181 gtagtgatcg acattttcaa tgtttgaata tcttttgata cagtgatttt taatttgaat
      241 ccttctttgc tttgcggcgt ggcatctaat ggtcggatca attgataatt gcctccgttt
      301 gtttctgtaa atccattatc gcgcaatgta tatctttttg catcaggatg caaacgatag
      361 ctaattggtg cgcccagtac cgttgctgtt gtttcaaatg ccatgatttt cacctcgata
      421 aaattagttt ctctttatta taaaagttta tcctgatttt tactaggttt ttcagttaag
      481 ttccctaaaa aatgaaggcg ttctctcaga catctgttca tataagaatg acttcactag
      541 ttattttttg acagcacgaa ctaattgatc aaggaaatac tggatgtcgt cttcggtatt
      601 tcccaaacca aagctgatac ggatggattc ttttagtatc ggtgtatctt ctccatacat
      661 tgcttctaat acgtgtgaag gctcgatatt tcctgctgta caagctgaac cagtagaaat
      721 agcgacccca ttaagatcaa gcttcatcag tagcaaatca tttgcttcgc caattaagcg
      781 aagattcaac acatgaggga gtttattcgt taaatcacca tttacttgat aagggatttc
      841 gtttgcttct aatgtatcaa gaatcaattg ctggaatcct ttatatttgt tgttacgtgc
      901 ttcacgttct tcaggtgaca gcagttcaac tgcttttgcc ataccccaga tccctgctaa
      961 attttctgta cctgcacgcc gcttttcttc ctgctccccg cctaaaagca atgcagggat
     1021 atttactccg tctcgtttat ataagaaacc gacgcctttt ggcccattga ttttatgagc
     1081 agagatactt aataaatcga ttcctaattc ttctggatgg atcgtttggt ttccgtacgc
     1141 ttgtaccgca tctgtatgga aataagctgg atgatccgct aaaagttcac cgatttcttt
     1201 gattggcatc aaatttccga tttcattgtt cccgtacatc acagagacca agatcgtatc
     1261 ttctcgtaac gcttttttga cctcttcgat cgacagattc cctttttcat ctacaggcag
     1321 atatgtaacg tcaaacccct ttgtctctaa atatttcatg gtattaagaa cagcaggatg
     1381 ttcgatagct gtagtgatta gatgtctgcc ttctttttga cgcgagaacg ctgtttctaa
     1441 gatagctgta ttatcccctt ctgttccccc actgttaaag atgatctcgt gaggttttgc
     1501 ttgcagactg tctgcaatga tttgtcttgc tgtttccaat ttttcatgcg cgtggcgacc
     1561 aaatccatgt atgcttgaag gatttccaaa cgtgtcttgc atgattgccg tcatcgcttc
     1621 aattacttgt ggatgcatgg gggtagttgc cgcatgatcc agataaatag ttttcacttc
     1681 attcatccct tccaaattat tgctaggcac attctagcat aaaatagcga acaaaccaaa
     1741 gaagagctca tttttgtcta gaggacgttt catgggcata gaaaaaagga gctgtgacaa
     1801 aagtcttgtc gcagctcctt gaagctgctc acttctgtca caacttcttt ccctcttttt
     1861 tttgtttatt cgaattcttt ttcttccaga cggaataacg gactcatcgg tgtattttca
     1921 tggatgcgtt tgaccgcttc acccattaat tctgaacatg taacgattgt taagttttct
     1981 ggatgacgat tttcttctgt gaaaacagaa tcagtgatac aaatatcttt gattggtgca
     2041 ttgtctaaaa tacttttcgc atgatcggac aataatccat gtgacgcaca ggcatatact
     2101 tcttttgcgc cgttttcttt taatacattt gctgctcgtg caagcgttgc tcctgtgttc
     2161 aagatatcat ctaccatgat acatgtcttt ccttgaacat caccgatcac ataaccaccc
     2221 tcagttgaag catcatctgc atgatctacg atggctaatg tgctgttcaa atattctgaa
     2281 agactacgtg cacgctgaac accgctgttt tttggcgaaa caactacgat gtcatctccc
     2341 gtcagaccta attgacggta ataatgagca aacaacggca tcgtaaataa attatctaca
     2401 ggaatatcaa agaatccttg tacttgaacc gtgtgcagat ctaaagtcag tactcgagtt
     2461 gcccctgctt cttcgatcaa gttagcgatc aatttcgcag tgatcggttc atgaggtttc
     2521 gccgtgcggt cttgcctagc atacccatag taaggcaata cgacattgat cgttttcgca
     2581 cttgctcgct tcattgcatc gatcatgatc agtagttcca tatagtaatc attgacaggt
     2641 gcattcgttg attgaacgat atacacatga tcccctcgaa tactttcttc gatattgatg
     2701 gaaatctcgc catcactaaa ttgcttcacg acgcttttac ctaattctgt tccgaacact
     2761 ttcgcgattt tttcagctaa tggacggttg ccattcaaac taaaaatctt caacgtgtca
     2821 tcctgatact tattactcat gtagtcctcc ccaaaacttc tctattcttc gatagtttaa
     2881 catatttttc caagattttc tgttaatttc agcaaattct taaggaagtg aaactgttcc
     2941 gttactccaa ctggcaggaa tgactttatg ataatcgccc cagttgtcgt gtactttgta
     3001 ataacgttct cctgtttcag tttcaaaata agcgtacgct gtcacccaat gattgccata
     3061 tgtactgcca agtactttca aaataccaat catcacaggt ttgccttcac gtatacgttt
     3121 tgtagctcgc tgccatgaac ctagaagagt tgctcgtgca cgctcatgat tgccattctt
     3181 ctttaaaaaa ctagaaatcc ctgtactaac ctgaaaagga atcgtaggaa gtcctagtgg
     3241 ttggatctgg ctacgcaatg ccttcgtcaa aaccaacgaa tcagccgtat ttttcttgcg
     3301 aatctcattt ggaagcatcc accccttacg atagtcttga taataggcaa ggagaactgc
     3361 tgccgcgtaa gtaccacaaa gatagcctga gggggtagcc catttcttat acctcaaaaa
     3421 acgttcttct ggcaatccca cccagcaatt tgcgagttcc tttcctgacc ttttttcttc
     3481 gatcaaaacg ggaatatctt cttttctgtt gatccatcta gataactcga ttggctcttc
     3541 attgatcagc ttccattttt tacaagaaag accctcttga taagtatatt ttgctggaga
     3601 atattctacc ggatgtcctg attgatcgat aatcacataa ctttgatctt caaaaaccag
     3661 agctaaaaaa agcaatttac tttttcttga ctgcagctgc tgagtgctgg ctaatttttt
     3721 aattttttta tctactttga aatataaagg tttatccact acttgattca gttgggatcg
     3781 cctccttttt ttcattataa gtgaaggatt gaaaaaaaca aatcagtttg attgttcgaa
     3841 ttttcaattt tttatgttct atttgttaat tccttcattt tgtaagataa tgggcacacg
     3901 aaacaaaaaa ggagcgatcg atgaatgaac aaagaacgat tgaaacaaga tttctatgaa
     3961 gcagtcaatg aagaatggca aaaaacagca aaaatccctg cagataaacc agctacaggc
     4021 ggtttccaag atttagttga cgggatcgac caacttttga tgggagaaac agacgatctg
     4081 cttgcccatc cagaaaaagt gtcttcagaa aaaatgaaac atttccttgc atattatcaa
     4141 ctggcaaacg attatgaccg aagaaatgag ttgcatgctc aaccgcttca acctataatc
     4201 gaaaaagttg aatcattgca gtctttcgac gaattgaata agcaatttcc agaatggctg
     4261 ttggatacat taccattgcc atttaatctg gatgtagatg cagatatgaa gaatgcgcaa
     4321 acgaacgcct tctttgctta tccgccttct ttattccttc cagataagac gtattatgca
     4381 tcagaccatc ccaacggtgc acaactaata ggcgttttct ttgatatggc tgttcagtta
     4441 ttagagcttg ccggcaaaga aaaaagtcag gcagaagcaa tcacggaaca agcagtgcaa
     4501 tttgataaat tgattgctcc tcatgtaaaa agtgcagaag aaaacgcaga ttacagcaaa
     4561 atgtataatc cgcaatcttt tgatacattt attaaataca cagataaact ggacttgaaa
     4621 aaacttgtca cgggtttgat tgggacaact ccagataaag tgatcgtaac tgatccagtg
     4681 tacttcgatc atttgaatga catcctgaca gaagctcatt ttccgttatt caaaagctgg
     4741 atgatcatta aaacagtacg ttctcttagt ggttatctat cagaagaatt ccgccaagtc
     4801 agcggaatct attctcgcgt attgtctgga acagacgaag caatgcctca gaaaaaagca
     4861 gcgtattacc ttgcctctgg acaattcgat caagtagttg gcgattacta cggaaaaaaa
     4921 tattttggcg aagctgctaa aaaagacgta gaacaaatgg tgaaaaaaat gatcgccgtt
     4981 tataaaaaac gtctagaaga aaatgactgg cttggggatg caacaaaaga aaaagccgtc
     5041 ataaaattaa ataacttagg tatccaagta ggctaccccg ataagatccc agcattattc
     5101 gaccagttca aaacagtacc tgcagatcag ggtggtactt tgctttcaaa tactcttgtt
     5161 ttcagcaaac tcacattaaa agatcgtttc agcaaatgga acaaaccagt ggatcgttca
     5221 gaatgggaaa tgagtgctga cacggtcaat gcttattatc atccatttcg gaatgtgatc
     5281 gtctttccgg cagcgatcct tcaagcacca ttttacagtc tagaacaatc aagctctgct
     5341 aattatggtg gaatcggagc tgttatcgct catgagattt cccatgcatt tgataataac
     5401 ggcgctttat ttgacgaata tggcaacttg aacaactggt ggacagaaga agatcttaca
     5461 caatttcaaa acaaagcaca agcaatgatc gaagaattcg atggtctgcc ttttgctgac
     5521 ggaaaagtaa acggaaaatt aaccgtttcg gaaaatattg ctgatgcagg cggtctaagc
     5581 tgtgcattgg aagcagcaaa aacggaatca gatctttcta tcgaggaatt ctttgtcaat
     5641 tgggcaacga tttggcgtac aaaagcaaaa aaagaatacc aacaactttt actgcaaatc
     5701 gatgtccatg cccctgctaa actccgagca aacgtgcaac caaaaaacct tgacgaattc
     5761 tatgaaacat ttggtatcac ggaacaagac gctatgtatc tagcgccaga aaaaagagtg
     5821 cgaatctggt aagaggttgt gccagaagtg gtcagcttca agaaataaga aggaatttgg
     5881 gaaaatcgct tctcaaattt ttgtgacatt tcggcttatt tttcgaagaa gttacttctg
     5941 gaataccatg tattagaggt tgtgaaaaag ctgcttagtt tcaagtagta agaaaaattt
     6001 tgtgaaaatg gctttccaca tttttgcata aatttgactt actaccgaga aactggcttt
     6061 tgaacaccgt ttatcgagag gttgtgaaat cagcgtcctg acctgagtat tagagaaaaa
     6121 aacggaaaaa tagttcctca tattttgccg tttgttgagc taataccgag ggtcagctga
     6181 ttgaacaccg tttagtggag agattgtgaa aaagctgtcc tgcatcaagt aataagaaca
     6241 gccaatcaaa agcagcaagg agaacctcat ctataaaaag atagaaggaa gtgagacatc
     6301 tattggtctc atttccttct atttttactt tcctcagtca attgttttac atcataaaag
     6361 gagaaattcc acttattttt ttcgctgttt catgacataa acaactacac cgattaacaa
     6421 aattcctcca gctaatgcta gcaacgggtt attaaattct cccgtttttg ggagtccttg
     6481 agtgccattt ttttcacttt cttttgctgt cctatccgga tgagaaggtt ttccatttgg
     6541 ttttccattt ggtgattcat ttcctggatt ttctctttct ggtttgtcat ttcccggggg
     6601 cacatcggca gtttctcgca cagtgatcgc tttttgctgg gtaacagatt ctgtatgagc
     6661 agaccatttt tccccatcaa atatttccga acgataagtg acttctagcg tatattctcc
     6721 ttttgaaggt gctgaaaaaa tagcggtatg attagaaaat tgagcacttg actgtgtttc
     6781 aacgatttgg atcttttctg ggaaataacg catatcttca aagacaggcg ttccttgatt
     6841 tggtgtgaaa gttgacacaa aaactgtaaa aggcttcagt tcaatgatat ttccttctgc
     6901 attctccgcc acaccatttg cttcttgtat aataatcgga ttattttgtt catttggttt
     6961 tgtctgattt ggttcttgta cgattgcata ctctggatat tccgaagacg gtgaggtttc
     7021 tccgtcaaaa atagcaccta cagataatgg aagaccatcc actctttcct tttctgtttg
     7081 acgattcccc ggtttaatct gcatcagtcc atgaacatgg atacttccat tttcatagcg
     7141 cgtaacaggc tgctgacctt ctttcgaaca tgtatttaga gactcgatcc aatcttttga
     7201 tatggtatgt ccaagagtat tttctgattg tttctctcgt tcattccaat agtagttcaa
     7261 cgagtggtag atttgatctt cgttttgatt caatgggcgg atctgctctc tcatctcaag
     7321 attctctgtt cggaaagata agataccaga agcatggtag tctgtgtttc ctgctgaaga
     7381 ggtataaaga gccacattat atgaaccgtt attaaaactt gtactgctat tgacgataat
     7441 atctgttccg ctattggaat cgattccttt cgcaagattt tcgaaagaca aactattgat
     7501 caattcatga gggcccgtta aagaagaacc gcccattttg aatccattac cgttaccttc
     7561 tccctcaatt cctggtaccc agccgtttcg ataagcaact gagtttttga tgattacttt
     7621 tccgatcgaa cctgtttcat ttttagcaaa aaggtcccaa ccgtcatctg cattatgata
     7681 cgcgatacaa ccgtcaaata catttccttc tcctattgtc agtttggccg caaatccatc
     7741 ggcatcttca aatcctggat cggcattttc aaaagatgta cagttcttga ctaagttatg
     7801 cgcgggccat gcttcgaaag gatcatttga gctaccgctg atttggattc ctgtatttcc
     7861 attccgataa gcatgaatct cttcgatcaa attatgattt ccagaaatct gtaatccttt
     7921 ttgcatagct gcactatttg taatgtcaaa ccctcgtaaa ccccagtagt gactgaacag
     7981 tgtcatccca tttccagttc ctttaaaatc aagtacagga cgcttgtttt ctggattttt
     8041 ctctgcaatc aactgaatcg ggttttctct tgtcccgtta acgccttttg gaatcgtcaa
     8101 tcctctttcg aaggaataag ttccaggcgc catgacgatt gtctgcccag catatgcgta
     8161 tctcaatgct tgtgtcagag ataatggatt ttgtctgctt ccgtttcctg catctgaccc
     8221 ttctggtgtt acataaactg tcgaatattt aggtttacgg tagtccactg tatgaagaat
     8281 ctcttttgtt tcataactag tcatctctac gtattcttct ggcggatagt ttttatctgg
     8341 cgtaaaactg aaagtaaatt cgttcgttcc ttccatcagt tttgtctgat aatcaaattc
     8401 ccgattcgca gtgatagcca agttttttgc gttcttaagc acctctcctg ttgctttatt
     8461 tttaattgtc aataatccgt cagcatttgc tctaaaggac atagtatgat cttggtttcc
     8521 tgaatgatta ctagaggtca cagtgtaaat cggatcaatc aagcgagtag gtctttcttg
     8581 cccaggagga tctgtcgcag gatctgagta agcaacttcg attccttcta ccttgatcgt
     8641 catattcctt gctgcagcaa atcctgcata aataaccgat tcatctgaag cgtataattt
     8701 ttcccagtca tacatgatgt cagaagccat ttcttctcct gtttcaggat cgtaataata
     8761 tgcctctaaa ccagtattcg tttttttcat ctctacgtcc agtttagtaa tcgagttcgt
     8821 ggccggaaac agattcccat gaccgtttcc gaatatatta taagaacctg tttctttttc
     8881 caagaaccct gctgaagtct ctaaaggtgt tgtttccact gagacactcc caggagctgg
     8941 cgcagcttgc ggatcttcag atgatattcc tgtgattgcc cgtgtcccca atccaagtcg
     9001 catcgtatat ttgctgccgc tcgtgttgac cacttcttgt ctatccgagt cccagacata
     9061 ttcgatccga ctgcctagta tggcaaatga atttgaataa aatgcctgcc caaacaaatg
     9121 attttttggt actgcgtctc ttaccattaa agcaaatcct tcttgggcat tcgtataggt
     9181 ccaagattct atttcgatcg tcgcccgcat cctaaagttg atgtctttgg ggattgcttg
     9241 ataataatag gtcattccat ctgatccgct tgactggaat tttccgccgt tattcgtgga
     9301 agagagccgc acgccgtctt ctaatggttc aatggcatac ctactagcac ttgtgctttc
     9361 tccgaaaaca acccctttcc actcttcatt tgcttcttca gattgctttt ttgtcttttc
     9421 attttctgat tctttcatca taggatcatt tccttcttcc gtatccatat cttcactagt
     9481 tcttggtatt tcctccattg ttgacatccc ttcaatgttc acgtgtgcat tttcttcgtt
     9541 cacagactgt tgttcgttag cagcaacttc aacgacagaa attaaaaccg gggtactgag
     9601 cataaggaga ttcatcatta gcgcactgta ttttatacgt ttttttaaca agtgtattcc
     9661 tcccgtaaca aattagaaag cgtttactta aagtattacc taatttattt ttactgtcaa
     9721 taaaaaacaa aattataata agtgtatttt ataaaaagaa aaaatataac ttaagttgtt
     9781 gataataaag agatttatta acggaaaaag aataagtttt tttaaaataa cgtataaaaa
     9841 agagcataaa acaaagtcgt ttgttttatg ctcttctttt attattttgt gctttttatt
     9901 ttatcaaatc actttgtttt tttataaaat ttctgcgcct agtgtggact caaaatgtct
     9961 caatgcccat tcatgtccaa cgggatcgaa acttgccacg gaatctttga aaatatggag
    10021 tttgtatcct agattatacg catcgactgc tgtatgcaac acacagatat ctgtacatac
    10081 gccggtcaaa taaatatctg tgatctggcg ttctcgcaaa cggatgtcta gatctgttcc
    10141 actaaaagcg gaataatgcc gtttgtctat ccaataaaca ttttcctctt gctcatagtc
    10201 ttggtataaa ctttttaaag agccgtacaa ttcccgtcca cccgttccta tcacattatg
    10261 cggaggaaat aagcggttct ccggatgaaa ggaatctttt ggatcatgcg catcaatggc
    10321 aaaaacgaca aaatcctttt gatcaataaa cttctttgta tgagcagtca gctttttttc
    10381 aattacttgt cctgctgtcc cagtagtcag ctttccatcc tctgcaacaa aatcatatgt
    10441 gtagtcaatc gagatcaatg cgttcatctt agtcctcctt atacgagatg tttgacaaat
    10501 tcgatcacca tttctgctga tcgtttgcct gcgtcttcga taaattcgtc aaagctttgt
    10561 gtcgccgagt gatctgctgt gtcgctcatt gcacgtacga tcaaaaatgg gatattgaac
    10621 tgacgagctg tttgtccaac agcggctcct tccatttcgc aagctaatgc ttcagggaaa
    10681 ttcgttaaga tttctttgat tttatctggc gagtcgacaa atgtatcacc tgtaacgatc
    10741 aatccttctt ttgcgttcaa attcgttgct tttgctgctt taaccatttc actgcgcaaa
    10801 tatgtgcttg cttcataata tagaggcatt cctggtaatt gtcctgggtt gtagccaaat
    10861 cctgttgcat ctgcatcaaa ataagctact ttgtctgata taacgatgtc acctacttgt
    10921 aagccttcac cgattccgcc agctgaacct gtattgatca ccatgttcac gccgtattgt
    10981 tggatcaaca gacttgtggt aatagatgct aagacttttc ctataccgga acgtacgacg
    11041 atcacttcgt ggttacctaa tgaacctgaa ataaataaag cgcctgcgcg ttcccatgat
    11101 aatggttcgc ttaggttctc tctcaaaatt tttacttctt cttccattgc gccgataata
    11161 ccgattttca tctttttaat tccttctttc tatataaatg cgattgctaa aaaaaccaca
    11221 cataacatta ggataacaat aataagagat ttcatcaaaa aagagttcca tttggtcgtc
    11281 ttttcccgtt cgctgatcct tgttttcgtg attggtttat tctttttgct ttctttacga
    11341 taaaagctgg caatcttttt ttcttcttgc tgataagctg tttctgcttt tcgctgtttt
    11401 tttaatgact cgcttgcttg tgcttgttgt cgcttgcgaa gttcgcttcg cgtaataagc
    11461 ggtcctttgg ccataagccg atccctctac tttcctttgg tcaatagttc ccagtattga
    11521 atcgcataaa tcgtctttgc atcacaaatc aactgatctt tcatcgcttg ttgcgcctct
    11581 tcaagagtta gatgatacaa ctccagtact tcgtcttcat cttgtgctaa aggattctcg
    11641 accttctcta ccccttgtgc atgataaata tgaaggactt catttgcaaa acctggtgaa
    11701 agatacatcg aagtaagatg gctcagcgac ttcgcacgat agccagtttc ttcttctaat
    11761 tctctagctg ctgtcatttc gggattttgt ccttctcctg gatcgatttt tccagctgga
    11821 atctccaaaa tcactttttc taaaggtttt cgaaattgtt tgacaagaag cagacgatct
    11881 tgttcgtcaa aagcaatgat cccgacaccg ccaggatgaa ataccagttc tctcttcgaa
    11941 gttcctccat ctggcaaacg aacttcgtct acagcaacat caataatttt tccgctatag
    12001 atttctttgc gactgattgt tttttcttca aattgctcat tgttcagcat atcttctcct
    12061 gctttctttg taatcataac tgcttttttt tcatttttca atttttctca aaaactcctt
    12121 attagtttac catagataaa ccttagattt tctctaaata tagaaaatcc ttctttagtc
    12181 cgatactctt tctagtagtc cgtatgctaa aataagtatg taatcgaata acgaaaagaa
    12241 ttcaatactc aacgataaat gacatggagg gtttattatg ataaaacgaa attggccgtg
    12301 gcttctagca ttggtcttgc tatttctctt tgtccgaaac aatagttttt cttttgttct
    12361 aggactttta ttgataggtg tagttttagt tttgtgggga ctctttggtt cgcgcaggaa
    12421 aaagggaaaa caagaagaaa ttcctgcact gactgacgaa cttgaaactc actatgaaaa
    12481 aagcggtatg acagcgaatg aaatttcatt ttttcgacaa acaatgaatc aaacaaaaaa
    12541 tgagatcaat caattgcaaa tgaatatgca gcagacagcc aaacttaaag caatcgatct
    12601 ccgccatgat ccagtcaaag cagcgaaagc tttattcaaa gaattggtga aagaaccaaa
    12661 ccgactgcat gaagcaagtc agtttcttta tacgcatctg ccgaatctag ttgatttgac
    12721 aaataagtat aatgagatca atgaccatga gatcaaaaac aaacagacct atgaaaaact
    12781 agaagaaagc gcgcagatca tcgaccagct gtcagcttta atcgcacaag attatcaaaa
    12841 attcgttgct gaggatctag atgatatcga cgtagagata tctgttgcga aacagagctt
    12901 aaagcgtgat aataaatatg aaccagaaca aaaggattaa ctcttttgtt cataaaagaa
    12961 gactcggaac attcagatga tgtctggctg tttcgagtac tttttctaaa gtagagacat
    13021 tcatgtaaga atcgagaaca gattcaacaa ggaggaattt tttatggatc ataaaccgac
    13081 tgaaacaaaa gatgttacac cagttaacga tacacttgaa gatttattga acaacccgtt
    13141 ttcaactcca acagatacgc tgaccacttc acaacaagcg gagattgatc agctccaaga
    13201 gcaacagaca gctgctcgtt taattgacaa actaccggcg gaacgccaag aacaagctaa
    13261 acagctagca gcaaaaatcg atgctaatga tgcacagtct gtcatcagct acggatcggc
    13321 tgcccaagca aaattaagtg aattctcaca atcgatgttg aatcatgtgc aagcacaaga
    13381 tattggtcct gtaggagatt ccttaactga actgatgtat cgtctccaag aagccaatcc
    13441 tgacgaactg cgtgccggag aagggaacat cttccagcgt gtcttcggga aggtcaaaca
    13501 atcgatctat gaagtgacag caaaatatca aaagattggt gcacaaattg acaagatttc
    13561 agtgaaatta gataaagaaa aagacggtct gctaaaagat aatctgatgt tagaacagct
    13621 ttaccagaaa aacaaagact actttgatgc actgaatatt tatatcgctg ctggagaatt
    13681 gaaaatggaa gaacttcaaa caacgatcat tccagaagcg atgaaaagag cagaagaaac
    13741 tggcgatcag atggatgttc agattgccaa tgattacacg caattcctag atcgtctgga
    13801 taaacgtacg catgatcttc gcttagctag acagatcacg atccagcaag caccacaaat
    13861 ccgtttgatc caaaacacaa atcaggcctt ggctgaaaag atccaagcat ctatcgctac
    13921 agccattccg ctgtggaaaa accaagtcgt gatcgcattg accttgcttc gtcaaaaaga
    13981 tgcagtaact gctcaacgcc aagtctctga aacaacaaac gacttattga agaaaaattc
    14041 agaaatgctg aaaatctcag ccatcgaaac agcgaaagaa aatgaacgtg gaatcgtgga
    14101 tatcgagacc cttcaaacca ctcaaaatga tttgatcgaa acaatccaag agacattgcg
    14161 tatccaaaaa gaaggaaaag aaaaacgtcg tcatgcagaa gtagagcttg gacacatgga
    14221 agaagatctg aaacaaaaac tgttggattt aacccaatag atcacctttc gcttgttact
    14281 aaaacaaacg cccaacaaca gtttattaca actgttgatg ggcgtttttc ttatctttct
    14341 tctaacttct ccattggagt ctatttctca ttcatcttgc tgtgtccata gccatagcca
    14401 aaataaatga tcagtccaat aaccattacg ataccgaaca cgatccatgt cacagtttgc
    14461 agacgaagca tcaatacaat acaagtcaag atggagacga ttggcaatag cggaacgaat
    14521 ggcactttga attctccagc ttttggtttg ccaaacattt ttctcaactt cagtaagcct
    14581 agactaacaa gcatcaaata ggcgagcgcc atgatattcg ttagttccgc taatacattc
    14641 aatgggaaaa atccggcaaa gaatacagct gccacaccag cggcataagt cgcttttttc
    14701 ggtgtacgat gcttttgatc gatttctgtc ataaacttag gaagtaagcc atccttgctg
    14761 acagcaaaca gtaaacgagc aagtgaatac atcatcgaga tcgttaccgt cagtagcgtt
    14821 aaaattgccc ctacagcgat caccgcgccc actgttccat gtcctacata cctcattgca
    14881 aaagccactg ggtcattgac tcctagttca gtatacggaa cgattcctgt caagatcagc
    14941 gtcacgatga tgtaaaggac agtagcaatc agtatcgaac caatgattcc tcttggcaca
    15001 tctttttgcg ggtttttgac ttcctcggct gccattgcaa cggcatcaaa tcccaagaaa
    15061 gcaaaaaaca caagagctgc accatctagc acaccggaaa aaccaaaagg catgaatggc
    15121 tgccagttat caggtttaac gaaaaatatt cctacaatga taaacaacgc gatgatacca
    15181 aatttgacat ataccatggc attattcaaa cgtaatgctt tcttggcttc aagcgacacg
    15241 atgtaagtga cgaatatcac tacgagcacc gcaatcaagt caatgtatgt accattttcc
    15301 ggattgtacc cgccagttaa tgcttgtgga agttcggccc ctaaactttt caaaaaacct
    15361 tgcatatagc cagaccatcc ggaagcaaca gaggaaaccg ctagtaaaaa ttccccgatc
    15421 aacaaccacc ctgtcagcca ggcagcaaat tcaccaaata caacatacag ataggcatat
    15481 ggcccaccaa tcactggcac tcgcgaagca aattctgcga aacttagtcc agacaaaatg
    15541 acaacgattg cagctaagac aaatgaaagt gacagtgctg gaccagcatt ttgattggcc
    15601 gcaacccctg tcaccacaaa tattcccgta ccgatgatcg caccaattcc aagcatgatc
    15661 aaatcagacg tttttagttc ttttttcatc tcactcgtat gattgagatt gatctctttc
    15721 ttacgaaaca aatccattga agttcctccc cattttaggt tggaaaacag cgattaaact
    15781 gttttcatat accctaaaag gataccacct aaaatgacta aaaggcaacc aacaataaca
    15841 taaatgagct cttttttcgt ttttctttcg ccaaggatga aaatcccacc taaagtagag
    15901 ataatgatcc ccatttgtga aagtgagaag ccaacagcta aaccaagtga tttgactgtt
    15961 agaagcatgc agatgtttcc taagccccat aataatccac agatcatgtt tttccacaca
    16021 aactgatcga ctttaacttt acggaaagca aagaagcttg cgcctaagat cattccgata
    16081 ctttgaggta agataattga catcgcatcc aaattcgccc agttgacgat gatggtatat
    16141 acaccataac caatcgtaga gaagatcaat gctctaaaac ccttaccaaa atcaagcatt
    16201 ttattatctg tatctatttt tccttcgtca tcttgtcggg cagtcaaata cgcaccgctt
    16261 acaagaagag ctaaagcaat aataccgtat acataatctt tcgtttgtgt ccattcatgg
    16321 aagaaaacgg ctcccgcaat cgtattcaaa attaattgaa aaccagtaga caatggtagc
    16381 cctacagaaa cacccatgta cttcattcca tggaactgtc cattttgtcc aacactccaa
    16441 gctaagccgg ataaaaatcc gatcaagaaa atccaagggg tgattacagg actaacaacg
    16501 aaaaagacaa ctaaagaaaa cagaaatgca ccgatcgtca ttcctagtgt ttgttgattg
    16561 gcatcgccac caattttacc acttactaaa ccaatactac cccatgccaa catagggact
    16621 aatgctatta aaatttccat aaccaatctc cttttatttc acatgataag aaacttatca
    16681 gcgaaaacgt taacaacaca agcacttttt ttcgtttcta acgattttct aacgtttttc
    16741 attataaaaa tttaagattg ggaaaaataa agtcattgtt gtcccttttc cttcagttga
    16801 ttcagccgtc aaatggatac ctaatttttc ggccagattt tttgctaaat aaagtcctaa
    16861 tcctgttgaa tgtgttttgc taagtcgacc atttctccca gtaaatccct tatcaaagat
    16921 ccgtttcaag tcttccgctg ggataccgat ccctgaatct ttaactgaaa ggctgactcc
    16981 ttgcgcttcc ttttctatgc tcacaatgat gtttccgtga tccggcgtat atttgatggc
    17041 attactaagc aattggttga agataaaagc gatccattta gcatcggtca aaacagtatg
    17101 atcctcacca acgatctcgt agcgaatatt tttttggata aaataatttg cctgactgcg
    17161 tatcacaggc tgaatgattc cttttagtcc atattcttgg atgaggtagt cccgcgagaa
    17221 actgtcgagt cttgcataat acaaaacttg ttctacgtat tcatcgattt ttgataattc
    17281 attttctagt aatgtatact tttgatcgtc aatatcgaac tcgatcgaac gaactagcaa
    17341 tttagaagcg gaaagtggca ctttgatttc atggacccat gagtcaatat aatctttttg
    17401 gtcttgttga ttactgattg ctgattgcat tacttcttgg tgttcacgga tcagctgatt
    17461 gatatattct tctaccagtt tttcttcttc tgtcctccca ccactcaaat aattttgcaa
    17521 aggggaagtt ttttgtatgt cggctaattt tccccaccat cttctcttgc tcaagtaacc
    17581 acccagcaga taaaaaatca gaaagacgcc ctcaatcaaa gctaaataag caattgtgct
    17641 caaatcaact ttgatgtttg gcgccagcca catcacaaag atcgtcaatg caataaaaaa
    17701 cagccatccc aagatcaatg tccactgatc tttcaaatat ttaaaaaaat tcatcttaac
    17761 cgctcatcct ttcagggaac gatatatccc tgtcctactt ttgtttcgat atatccttgg
    17821 atacctgcct attcgatttt tcggcgtaac cgattgatgt tgactgtcaa tgtattgtca
    17881 tctacaaatc gttcgtcatc ccacagtgct cgcagcaatt tttcccgact taagatcttt
    17941 ccattgtgct tcatcaaaat aaataataga cgatattcat ttttgctcaa atcaatgatc
    18001 tctccgttga tttccatact tccgttgtca acattcaacg taatgccatt gtggctcatc
    18061 atttcactag ataattctgt gtagttgtaa gaacggcgaa gtaatgcatt gatttttgca
    18121 atcagtacat cgatttggaa atgttttgtc acaaaatcat ctgcccccat gttcatagcc
    18181 atgatcatat ccatattcgt attcctgctg gagataaaaa tgatcggtac tttcgatact
    18241 tcacgtattt tttgacacca ataatagcca tccaaaacgg gaagattatt atctagtaat
    18301 acaagctgtg gttcttctct ttcaaagtct gagaacactt gattgaaatc ggtcgttcca
    18361 aaggtttcaa attgccattt ctcaagttcc tccatgatca attgtcgaat gatctcttcg
    18421 tcttcgacta ccatgatttt tgccataaaa aatccctcca tctttcttct tgctactaca
    18481 atatcaaaga agcccttgtg aaacaagttg gcttacctgg aaaatgtcat tttagcaaac
    18541 gttaaaaaaa actggaaata tgcgatttaa tcgcgtttgt ctcttccaag cagcttaaat
    18601 ttattatgtt attcttaata attggtctat tatctgttat ttttctttcg ttgtttttgt
    18661 cttttaaatt ttcgataaca ccaataaccg aaaagcgtta gcactagcaa tatacctaga
    18721 aggagtataa gtaatcgata aagatggtat ttttttgtct gttctatctt tgaagagact
    18781 tcttctgtaa agggaactcg tcttcctgtc actagtaatc ggtgagtgtt cacggtgtaa
    18841 ggtgtacaag tgataagtgt gactagatcc tgcttttctc taattgctaa tgtatttgtt
    18901 tttgttggaa ggacaacaat tttctcaacg acttcataag cgagcatccg accatacact
    18961 tcaagataga atcggtcatc ttgctccatt tcttcaagat ccgtaaagag ttttttctca
    19021 gcaataccgc tatgggcggt aatcacggaa tgtgtactct ctcctccagt tggaaaagag
    19081 gtgccttgca ggactgtcgc tcctctatct aacaaaagat cattcgtttc atcaaataaa
    19141 ggcaagctaa cattgatttt cggaatatag atggctccga tcatatgttg ttcgtaatat
    19201 tcttttcctg gattttggac atttctaacc gcttgctcaa aaggatcttt gacttgtccc
    19261 attcctggga ttactgatgt atgagcaagc gtctgatttt tcttttcatg cactgctaat
    19321 tgttgctcat gtttttcttc tttatcgcgt tcaagctgct tttgataatt ctcgatcctt
    19381 ctttgatcca aataattgct gagagcatct gctaaaaatg gatatgtaaa aactgcagct
    19441 ccggcaagaa acatcactgc cataaataat tgtaataaaa gactgatttg ggtttgaggt
    19501 ctattaccta ttttcttttt cattttcttc accttcttat ttaaaaaaac tgcagcaacc
    19561 tttataaaac cgattgctgc agcttatttt tgttgcttat acttcagact tcattttaga
    19621 tttacggtac cagctgtacg ctccaatcat caaacttatt ccgattagta agaatgccaa
    19681 gagcccgttc ccaccagtag caggaagtga cccgcgtttc atattcggta ctctttctgg
    19741 ccctggattt tctactccta cgatctgaat ttcttcatta tagcttccat aagagatgat
    19801 aaattcagta aaggctgcct cacctgttgg aagtacataa ccttctggcg ccatggtctc
    19861 tttcatttga taggttccat aatctaaccc ttgaacctca aagtatccat ttccatctgc
    19921 gacaaattct gttgcttgtc cgcttgttgc ccactcaatt ctatctgctc ctgattcata
    19981 aacagctaaa ggcgactccc ctttataaaa tattgcgtat tcagaacggt cttcattcca
    20041 caattcgaat cttgcatctt taagcaattc actgcttgat gcatcatatt tttcaaactt
    20101 tcttccacct gttgtgactt tctctggcgg ctctactcct tcttcataat caaattcatc
    20161 atttcgtccg atttcaataa ccgctgtgtt gttatggaaa tcatccgctt ctagttctgt
    20221 ggaaaccttc aaattatacg tgatcgttaa atctcctcca cgtgcatctg ctaatctacc
    20281 taaagtatct actttggcta ctccattttc ttctgtcaaa atcgtcacga caaacccgtt
    20341 gcttactact tctactatat aatcttgtcc ttttgttaaa atcgtctcgc cggctcgcac
    20401 ttctatttcc tgatcataat aagttagacc aactgtaggc gtatctgtga ttttgtaatt
    20461 tttgataaca gcgcttccgt tttcaaggac agaatcgatg aaataaggaa taggtgctgt
    20521 gatcgtgtaa gaagccgttt ttcctctttc tagatcaata taagaaatcg tttcttgttc
    20581 tccagcttca ttaataatcg ttacttgtct aaggtcgctt tcctctacat tcatctgttt
    20641 atctgcttct ctgatttcgt ttttcggata caaatgcaca tctgtattgt atgtgtcttt
    20701 ccatgtagaa ccatcccaca cgccatccac catatcaggc atcatcactg gcatcataac
    20761 aaccattgga gacgcgattc tggaaatatg agctggcgaa taagtttcta agaaaagata
    20821 gactttatct ctagaagaag gtgcttcttc cgtcacttgg acggtagaga ataccgcttc
    20881 tccagcttca ttcgttgttt gtttgtcaat acttgtcagt cgatatttta aaaaccaact
    20941 ttctgtgtgc cgtttttgaa tccattcaat cgcttcggca gaattaagac cgtcttctcg
    21001 ttccggtgtt aaaggattat ctcgaatcaa atcgtaatat acttccgtta cgtcaaacaa
    21061 atcaaaatcg actcctggaa tattttcttc accaaaatcc gtagaaacca atccgctatt
    21121 cggtcgttct tccggaacag atgagaaacc ttttttgtgt aatgtaatcg tcacttcact
    21181 tggtttttgt gcgacttctt cggctttgac tagttttccg ttcccgaaaa tccctattcc
    21241 cgcagtaacg agtaacagta cactcattcc cgtgacaatc atttttttat tcattttttt
    21301 ctccccgttc tttttttatt aataaaacag cacctaacaa taaaagaatt cctagtaaag
    21361 aaatcaacgt tcttgcttca ttcgtttgcg ggaatacgga ccattttcct gattgacctg
    21421 gattgcttgg accactcggc tctttcggtt tgtccgttgt ttcttttacg gtctcgttat
    21481 aaacacgtgg tgttgcggat tcataggcag agactggaac tttcccggat tctaattcag
    21541 ccatctcctg tccgttaact actacatatt gtggttggcc ttttgcatcc acccaaaatt
    21601 cagggatgat gacctcgatt ctcttacttg cttcatccat ctcgtaacct tccacacctt
    21661 ttaattcttc aaaataatag gtgccagaag gcaagaaacg ttgtcctgtc gtaacaaggc
    21721 cctctttatc cgaaatgaat ttgcttacat ttttgtcatt caaaggatca ttgtctgctg
    21781 gtttgatcca ttgatttttc aagtcattag caggagccat atctaaataa tatttccccc
    21841 cttctatcat ctgatataga gcaaaaacag caccttctaa tggttttcct ttttcagttg
    21901 ttcctctttg acgtccatac ttgaagaagt atggatctct tagataaccg acatttttag
    21961 gatagatatg aatctcttgc agttcctcgg ttgattctgt cgggtgataa attggcaaaa
    22021 tagcagcaat tgggatagct gtctgatcga tatcaacatc caatccaact tctggatcaa
    22081 tcgattcttc gaaaatcaaa taaactgcat cccgatcttg gtttttctta ggtgctttga
    22141 tacgtgcaat cccgtctcct aatccgccaa ccgtatcttt cccagttgtt accgaagtcc
    22201 ctatttggac aagcctttct tctgtgatta gctgacggat attgtttctg ttcgtttcag
    22261 cgatttgctg gacgaattct ttaggagtca tgttttcagc agcttttttt tcatgataat
    22321 aatcggtcat gtcgtaaatg gcaaatgtcg ctccatttag tggcaccgtc tgtgaaatga
    22381 tatctgctgt ttcccctgct tcctcagaga tagccaagcc atcattttca tggtattcaa
    22441 attgatcgtt ataatcgata tctcgaatca tccgtttatg caacacgaat tccacgacat
    22501 cttcccctga ttcttctgcc gacatcgcat gtggaagaag gactgctgca agcggtagta
    22561 aaacaagtaa ttgaagcatc aaacacaaca gctttttcat taccttgctc cctccttttt
    22621 agattgtctg acaaacaaac cataggctgc tcctgcaagc gccatgaaga atgcagcaag
    22681 caggatatag aataatcgtc cggatcctcc tgtagcaggc aacggatttt caggatcgtt
    22741 cccgacacta agctgtaatc tgattcgatt tgtctccaaa agttcatatt ctaactcttg
    22801 ctgtagatca ggcgtctctg cttcttcgtt tggataatac gaaatctcaa cttttagtgt
    22861 acccgcttct tttcctggaa ctacccgatc attttctatg tcaggttctt ctcgataact
    22921 aatttctaaa ataaagtaac ctggaagttt tctatagctg tcaggtgact tcacttcctt
    22981 gatccgatag accccttcca acaagtctga agcattgaat agggaagaat cgtttggatc
    23041 tggtgccaag cctccctcga tgatttcata ctctcctgca ctattttgtt tctcaattga
    23101 aaattctgcg ccttcaagac gtcggctatt catactgtca attttcaaaa gttccaaatc
    23161 gattggcgct agttcatctt ctaaggttac ttgtagtaca ccatcgatga tttcatagcc
    23221 ttccggcaag ggagcagttt cgtcttcgat gaccgtatct tcaatgataa acttaccttc
    23281 ttcattcagt gcaaactgga acacttgatc agatagccga tacccatttg gtgcgacaga
    23341 ttccgagacc tcatattcac caatagacag atgcagaggt tggtcgtaat ttaaatcgac
    23401 atacttttct actcctacgg cacgagaata gaagtatccg atcccaggca aacgtttcga
    23461 ttcttctggt tctaacggat taccagtgta tgctcgatac agcgggaagg aagaatcccc
    23521 cactttcctg atatcgaaac ctgcaccatc taatgtatgg ccttcatggt ctaattttct
    23581 aactcggatc tcccgataat caaacgtatt gtaagcagtg aatgctaccc ataaacgatc
    23641 ctcttcatct gttgtatacg tgagatattg ccaattttct tcacctgttt gcttgagttg
    23701 gatagtccct atagcattat cgtaaagtcg caagatccat gtgtcatttt catcaggttc
    23761 tttgaaacct tctgggttct ggctctcaat gattttgtat tctgcatagt tggtagtttc
    23821 ttcactatcc ttataaacaa atgaatctgg ctctccgatt ggatgaataa ctttctcacc
    23881 atccacgatt acatatttcc cgtcttcatc tactgaatag aacgtgagtc tccctttctc
    23941 ttcctctact tcgttcacac cagaaagccc tttcgctact ggatatccga tttccagtcc
    24001 gttaccatct gtttcataaa gttcaaactc tgcgccattg attggcatat tactgccttc
    24061 aattagttta ttgatattca tgtggattgg cttgaattca tttcgcattt ccagtttgac
    24121 atacaactca tcatactctg tgccttctat gttaggctct tgtacaacag aaagcttgtg
    24181 atattctcct tcataatagg aattcggatc tttaccttcc ggtccgccga ctctcgaacc
    24241 agatgtatat tcatctacaa gctcgtagtg acctaacatc tcatcttcgt tggctgcata
    24301 ttttttgatt tggaattgat acgtctcatc tactaactga taacgtggtg gtccagcgat
    24361 ctctctgatc caaaatatgt cgctgactgc tccagtttca tctcctaaaa tcggcatctt
    24421 cgtttcaaag atcgctattc cgtccgtggt agttttactt gtttcgattg gttcggcttc
    24481 cccactctct ggattttggt catataatgc aaattcgact ccagccaacg gctcgccatt
    24541 ttgacccttc ttgctgactt ggaaattacg gcctttatgt tcgtaacgaa tggaagaaga
    24601 tgggaaatac atccgtccag tagtgatatc attctcataa tcctccaggt tctgaatata
    24661 ggccatattg ttcactgtgc aaaaatttcc gtcttgagct cccgcatcaa gttttacttg
    24721 gtacttgatc ctgaccattt ccccttcacc taaagaaatc ggagaaaatt tataagcttg
    24781 gttttcccgt ccgacatacg ttgtcggagt cgccactact tctggtgggg cttgtccatg
    24841 acgttcttca tcccatattt ctggctcttg gtacttcatg ccgttttctc ctggatctag
    24901 atggtaaaac tgaatatctg ccgatctgcc agctccaaat ggtgagacat taaaaccagt
    24961 ttcatcataa agtgtggctt gctggatcgt tctcttgaag gtagaagaga tatcctccaa
    25021 ggctgtaaca atgtcattct tgttgttcgc attgtaatat cgcggtgtta cgccatcttc
    25081 ttctaaatca gcaatatttt tcaatacatt tcgtccaata gcatctagtc gttgtctccc
    25141 gctaacgttt ccatcgattc ctaaaccaat ggagaagata cttggcgggt tctcttgata
    25201 cttgtttttc agccaatgat gataagcaac tgtgttgatc gcagatgact tttcttgcga
    25261 agtaggactg ccattcgtat tgttattaga agaaccatca ccaacccagt gagtcgcttt
    25321 attatctcct tcttttacct ctccataacg atagtgtaca tttacttcat cttctggacg
    25381 gttaaagtca gatgcatagg taactggatg agtaaaccct gcattagaag tattcccaga
    25441 aaactcctca aaatttctga acaaaacgtc attatcttca gcaatcttat cttccatcac
    25501 agtccagttg ctccaagctc cattagtgct cgtacgataa cttgactgaa tcggtgcata
    25561 actgaaggtc ggtgtcccat ctcccacaac gattaggatt ttttctggat ttctattttc
    25621 tccgccattg tctttataca atgtttcata gccattttta agccctagtg taagcggagt
    25681 tcctccgatt ggtgtacgat ttaatgctgt attctcactt cccgtcaaac gattgatatc
    25741 atttgtcaat ggaaagatgt ccgaactgat ttgctcatgg ttattgatag ctgtactatt
    25801 atggtaaaaa ttcaccatac cgattcgaat atccagactc gggtcagaga gcagatcttt
    25861 actcatttcg tttactgcct caatcaacgc agcattttta gtttgactat tggtcccagc
    25921 ggttaattca ctcatactcg ctgacttatc tagaacaaaa acgatatcga ttggactgat
    25981 ttcctttttc tcgcccccga tgacatctag atagacattg taaagggttg ttgcatcttc
    26041 aggatgtaga tcagatgctg tgctgcttgg cagaacaggt tctacccatt ttttgatgta
    26101 cgccccgtta taatccaagt aactgttttc aaaattccgt tcatttcccc aaagctgaac
    26161 ggtttgagct ggaacgtttc tatcttcttc gcctgcagtt gatccattat tagtagcata
    26221 gtcgtaattt cgccagttcg ctcccccgtt tgtataatca ctatcatcga tcaagttctc
    26281 tccgtcatat ggcgagcctt tgtctccttg atagcgttca ttgctttgtg tccaatttcc
    26341 taacactttt gtatagtcat tcgttgtaaa cttcgggtag cgatgctgtt cgttttcaac
    26401 ttctccgcta ggatagatat attcataggg gtcttgcgta gctgttggcc caagacgctc
    26461 caaaataccg ttgaataact ggcgttgaat gcgctggagt gcttgaccgc tgggtacgat
    26521 tggttcgtcc agcttttcca tctcattttc ttcgctacgt tgaatttcag cggaatcttc
    26581 tgtatcagtt tcattttctt gtaattcttg gttatctatt ctttcatcaa ccaccacttg
    26641 aagaggtagt tacccttcgt tcacatcggg gatcttttct gtttcaaaaa tcaatgtgcc
    26701 ggtttctgct tcttttgaat aaacttttcc gacataccat tcttgaccat cgatcgtctc
    26761 gacttttagg tcttctccat cttcatcata ggaggataga cctgttccac gaacgttttt
    26821 tacggtacca atcccggcgg ctgccgcatc gattgctaaa cgtattctac cttcattggc
    26881 actttccttt ttttcaaaag ccagatgcca ttcaagggtt tcttcttttt caatatactt
    26941 cccttcaatt tttgcatagt cctcatctaa gaatacctca tcctcctttg tttctgttga
    27001 ctcagcagct acatccaggg tcgtcatatg atagactgac tggaaatatg gtccaaatag
    27061 caaactgaca gttactaact gcaaaagctt caattttaac cctttcacat ccttatactc
    27121 ctttcaaaaa tatttgtctt ctttcacaac aatcaacaaa acaatgccca tctaattata
    27181 atttaattta attttaattt taaatcaaat gatatccttt ttagttaaaa aacaccaatt
    27241 atacaacatt tattattaaa attaaattat aaaattttat aacgttctca tttaacaaaa
    27301 cttaagttat taagacaaat gaataaacaa ctacgctttc ctcgaaacaa aaaaataaag
    27361 cacaaatgcg catttacgca ctcatgcttt attcgtacaa ttaattcaga taacggcagc
    27421 gcataggatg ccaataacac ttcctaaaat agctcctcct aaaatgtcag taggataatg
    27481 taaaagtaaa aaaatcctcg aataagcgat caaacaagca aataaaaagg ctaatattcc
    27541 tgcaactgga cttaattcga acaacgcagc tactgataaa aaggctagcg ctgtatgtcc
    27601 tgaaggaaaa gaagaagtct tcggtttact tgtgtaaagg acaagccgac gatttttttc
    27661 ataaggtctt ttccgtcttg tcgttttttt gataaaaagc aaaccaacaa aaaaatagat
    27721 caaactgccg ataagaatgg ctagaccata ttctctagta tcaggtatca agactaaaac
    27781 agcagcaagg agcaaccaaa taaaaccacc attagagata ttactgataa atttcaaaaa
    27841 attgattttt cgactatccg ttttccgttg cttggcgaac ttgttgataa tactatcatc
    27901 gattttagca atcaaacgca acatgttatt cctccttttt aagaaccttt tcttgcgtac
    27961 gatggataaa aagcaggact tgaaaataaa acaagaaact gaaacctaat aaagcaaaat
    28021 agattggtcc tgcaaaccag aatgcgacaa gaaggatcaa cgtgcctgcc aaatagaaaa
    28081 gcgcgctttt gaaatcatta aaaaacaaga aaaatgcagt aatccaagaa gcttcttttt
    28141 gttccagttg aagcaagatt ttgtaactaa agagaagcgc gcttaataga agcaaaaaca
    28201 acgtagtata catcaatgta tagccaattc ccccacccca atagcggaaa atctgataat
    28261 cgatcaatag aagaagaaaa taaacacttg ctaaactatc ttgctttcca taaagagaga
    28321 agttctcacg aaactttttc cagaatagtg aaccgagctt tttctcttca ttttttttgt
    28381 aatgataaat catatacaga actgttcgac ttgcagttcc taatgtgaaa acaggcaaga
    28441 cgcacaggaa ccatagtagc tgtaaatgga taagacgtgg aatccattca atgatttcta
    28501 agaaataatc attggctttt ttaccaatcg atcgattcat catccttttg aacctcctgt
    28561 caaatccatc ccttcaatga aataacgttg tgcaaaaaag aacagcaaaa tcgtcgggat
    28621 caagacaagt gttgctcctg ccatcagata attccattgt gtcgttgctt ggttctgaaa
    28681 aacttgcaag ccaatctgta acgtgtattt ttcttgatct tggatatata acagaggacc
    28741 taagaaatca ttccaagctg cgttgaagga attgatcgca atggtaatca aggcaggttt
    28801 cgtcaatgga agcatcaaat gactccaaat atacaaatga ttcgctccgt cgatttcagc
    28861 agcttcgatc aattcattat tgatcgataa gtaaaattga cgcatcagaa atatattgaa
    28921 cgcattgccg aagaacgatg gaacgatcag gggcaaataa gtacctaccc agccgatctt
    28981 ggagaataat acatattgag ggatcatcgt tacaaacccc gggatcatca tcgtagaaag
    29041 aaccaaagca aacatcagct ttttcccagg aaaatcaagc ttcgcaaatc cataagcaat
    29101 aaaagaattt gaaaggacat taccgatcac tactagcaca gtgatgaata atgtatttct
    29161 tgcatagcgc caaaaaggaa aggcggcaat cgtatccaga tagttttccc atacgatttt
    29221 ttctgggaaa aaggtcggag gataacgaac gatttcttcc attggtttca atgaagtaaa
    29281 caccatccaa agcaatggaa tgatcaaaat gattcctatt actgtcatga ggacataact
    29341 tagtattttt ttgtttgccg attcacactg gtctttttga aataatccat catttgccgt
    29401 cacctccaga ataatagacc cacttaggtg caagcttcaa attgacaaac gtcagaacca
    29461 acacgatcag aaacaggatc attgacatag ccatcgcata accagctacg aacgccttgt
    29521 tccacatatg cagattataa aaaagcaaag aatttgcagg tccgcctgtt ccatttttcg
    29581 tcatgacata agcttcttga aaaatttgga aagaaccgat cgtagaggtg atcacatcgt
    29641 aaaaaataat aggagtgatt aatggcaaag taatactttt gaactttccc caaacgcctg
    29701 ctccatcgat ttctgctgat tcatataaag atctaggaac attttgtaat gtagctaagt
    29761 aaagtagcat tgctcctcca gaactccata ttttcatcaa aatcaacgca ggtttcgtcc
    29821 attgtggatc aaacagccaa gctggtccag ggatatggaa ccagcccaga aatgtgttga
    29881 tcaatcctgc agatggagaa agcagctgca tccataagat gtagactgct actcctgata
    29941 agactgccgg taaatagaaa gctgtacgga atacactgat tcctttgatt ttttgattga
    30001 gtactgtggc taaaaacaca ctgaaaatcg tcgtcagcgg tacattgaag atgacgaaat
    30061 aaacggtgtt gtataacgat ttccaaaata aatcatcgtg aacgaacatt cttttgaaat
    30121 ttgctagacc aatgaaattc atcttggatg tcaaattata atcggtgaaa ctaccaataa
    30181 ctgaaaaaag cataggccct agcataaata ccaagaaccc gataataaaa ggcgagataa
    30241 ataaataggc ccatcttgct tcttttttct ttcggataga taaacgcttc aaattttctt
    30301 gcctcctctg tacctagaca gtcaaaaatg gattattgat tttgcttgac taagttttct
    30361 actgcttttt gtgcatctgc caatccttct tttggtgatt ttgttcctaa aagaatctgg
    30421 tcaatctgtt cattcactaa tgtcgtgtaa tccggagcat ctaaaggaac tggtgtgatc
    30481 accgtatttt taaagttttc gtccgccatt tgatagatca tttttccttt atccgttagg
    30541 ttgtcattat tcactaaatt ctcattggct gtcttgctcg ccatgatatc aaaacttttt
    30601 tcgccgaatt tttcttgtac ttctggagaa gaaagatatt tgatgaattc ataagaggcc
    30661 tcaggatctt ttgctccgta tggtacttcc aagacgaatc cgccacccca cgaccaatgg
    30721 cctgaacctt cttctttttc tgggagctgc atcacgccaa aatcaaaatc atccggtgca
    30781 ttttccatca aactagagta ataattgata ttttgggcac gcatggctac taatccggaa
    30841 ataaatggat cagatacacc agacccaaat tcggcttcta atttattgat cgtatttttc
    30901 ccataataat cttgccagtc ttggatccac tccaaggctt ccactttatt tttagtatca
    30961 atcttgactt tttcatcttt gtcaaaccaa ctagtcccgt tatctgcgtt tagcgcccat
    31021 acatcagccc ctaaattcca taatggataa aaaccgatgc gtgtaaattc ttttccttct
    31081 tttttatcta gtttacgtgc tgtttcttct aattcatccc aagttgtcgg tagatcttgt
    31141 tcactgattc cagcttcttt aaatatcttt ttattataaa aaatgacttg tgtatctgta
    31201 ttgaatggga tcgcataagg atcaccttca tattctactg tatcccaaag ctgcggataa
    31261 aaatccttag aagtgtcttt ttctacatat ttggagagat tagttgcttg ctgtgcttct
    31321 gctctttggg caacggaatt tatgtcctgt acaataacat cgggtgcatt tccagctgtt
    31381 attgcagata aagatttagt ccagatgtca ccccatggct gatacttata atttacatgg
    31441 atctcgtttt gtgattgatt gaaatcctca atgatttctt cgatagcttc ttttcgtgca
    31501 ccggatcccc aaaaggacca gaaatcaata ttttttcttc catcacttgt tttttcagaa
    31561 gaatttgctg cacttgaact ggcatcgctt gcattacttg atccgcatcc tcctaataaa
    31621 aacaatgctg aacttgccag caaccctgta aacaataatt ttttcatatt ttacctccaa
    31681 attttaatgt aaccgatgcc ggttttaata taacgatatc attttgttct gaaaataaca
    31741 atttataagg tatgattcta aaaaaattat taatgatacc aatactttat ataattcgcg
    31801 agcgctttct ttgaattttt taatctttcg tagcagaatg agaatgtatt aaaaatagat
    31861 taggaggaat tttgatgttt agacaccaga aagaattgca gtttgaagca aaaccagatc
    31921 gtccgaatcc attaatcgcg aaatatctgc aggagctgat cggcggccaa tatggcgaga
    31981 tgagtgtagc tatgcagtac ctgttccaag gctggagctg ccgaggagaa gaaaaatata
    32041 aagatatgct gatggacatt gcaacagaag aaatcggcca cgtggaaatg ttggcgacaa
    32101 tggttgctcg tttattagag ggtgcgcctg ttgaagatca agaagcagcg atgcaaaaag
    32161 atccaacaat cggtgccatt atctctggaa tgaatccaca gcacgcgatc gtagctggct
    32221 taggacctcg tcctgctgac agcgtgggca atccatggag cggtgcctat atcattgcga
    32281 gtggcaactt gttagcagac tttagagcta atttaaatgc cgaatcacaa ggaagacttc
    32341 aagtagcacg tatttacgaa atgatcgatg atcgtggcgt aaaagatatg ctgtctgttc
    32401 tccttgcaag agatagctat catcaaaatc tatgggaatg tgcagtgaaa gaattagaag
    32461 aaaaagaagg ttcaatctta gtcccaagta ctttcccgcg tgacaaagaa cgaaaagaca
    32521 ttgcttatga cttctataac ttctcagagg gagaccaaag tagtgaaggt tcttgggcta
    32581 gtggcaaagc actggatggc gaaggcgaat atcaatggtt gaaagaacct aagatcgaag
    32641 gcgctgcacc aaaattagaa ccagtaacac caaaaatgta tgggacacct ccattcaaga
    32701 aataaatatc tacccgtaga aacacccgtt ttttgttcca cacgctttgt gagcaaaact
    32761 gactaaagtc attaatcata accacccttc aaaagggtgg ttttctctag agctataagc
    32821 tcaaatcacc ggccagcgcc taaagacgct ggctttcata ttttatgttc aagccatatt
    32881 gcctttgcca gttttgccca cctcttaaaa ggtttatgta ctactcctta gcccttaaaa
    32941 ggatcgtctt actctcgtac actcagctta tctaacgcac tatcatgttt ttcttgttct
    33001 tgaatgtact ttttgatggt cgcttcattt tgtcctactt ttgtcacata gtatccttcc
    33061 acccaaaagt gtcgataccc aaatttatat tttagatttg cacaatctct tgatgatctc
    33121 ctgaatattg gctcgatatt gattataaat tatttttctt ctatactttg gtgtgaatac
    33181 aatgtggtat ttacacatct actttgtacg ggctaaacta tttcccttta ttgctccacc
    33241 cgcatagcaa gtggttttgt atttcaatcg ctcggcgcgc tcaattaggt ctaaagacaa
    33301 taaatctaaa aacccgctgc ttcactgaca gaaacaacgg gttttcagaa aaaaatgaaa
    33361 tgaaaaagat ctcttacggc aatctatttt atttttttga ttttttataa atggaaaatg
    33421 cttcaagaag tccaagaaat aaagccgtat aaaaacaaga acctatgaaa tctttattta
    33481 ttagatattc aacagaaatc ccgataacac tagccaacaa tatatttatc agaagtgtaa
    33541 aataaggatg ctttttatag aatagaacta gtgttgtttt catagactct cctttcttca
    33601 tatttccaat taatcacaaa ttcacggcat tactagaaaa attaaagggg cgcagaagtg
    33661 gaaaaatact cttcgacttt ccctacaaac caggccatct tgtgtttaat aactatacca
    33721 aatctaaggt acctctaaat ctaaattcca tttgtggcgg tgacctccaa tttttaactc
    33781 ttctatctcc catccagtat acataacctt gatacttcga ccacttatat atcgaacaca
    33841 caaataccta tccattgcag gagtactacc taacttagtt gctacttgca tctaaataac
    33901 agctgaaaag ataggactta ctcttagtaa agtatctgaa ctattaattt ttaaactatc
    33961 atttttatcc tcaactacat gcacatctgt tgcaacttca ctttctgtct catccagata
    34021 aatgattaag gaatcgggaa ttgcaatatc ttcagctgac gctggaatag ttgagctaaa
    34081 ttagtcatca tatctttatt ataaaataac caacagcaaa aaatacaatg aaaaacaaac
    34141 ttggaactaa tgtatcatta ataaatgttg aaaaattcag caactcatta ctgtatgatt
    34201 ttagcagccc aaccaacata taccctataa aagctaataa gatggttagg aatcctttag
    34261 aatttttact cattcataga cacttcctta aataactttt attatagaag gtattgtaaa
    34321 taataatatt gacaaaaagt gactcaaaat aaaaaaaacc ttacattata ctggaatgaa
    34381 ctgtattgat agtgtaccta aaagctctac tgacataaga tcgtgtaatc ggtaaagtaa
    34441 ttttattaat tatacgggat gtaatcaatt agagaataaa ctaatcataa aaggtacttt
    34501 tacattcata attgtcgctt tgagattcta ctttggttca ctatctgacc caattgcaca
    34561 ttttcgatca ttacaagtat tggtgtcgtt agaacaacta aataaaaact agcggtagat
    34621 ttttcagaat ctatgctaat ttctgtatgg atgttccagt gatggcaaat ttctcttttc
    34681 attgtttttc ttgtcgcatg atatgccttt ttgtgttatt cagttaaact atagaaattc
    34741 tttcctagac agatcttgat cccaaatttt acgtttttga gcatcgatat agtttaaaat
    34801 gacattactc atatctaaag agtttagatt ttttaggact aaaactgtca gttgttcttt
    34861 ttcttctttc tgttaaagta ttgtcgcgac ttttcgtata cgttaagata tgtcgtgaaa
    34921 aaacaagttt tgtgacacaa aaaaacgaat gacttgagga aatcacctca atcattcgtt
    34981 taaaatgcta tatattcttt agtttaagat acggaaatta atgccatcga ccacactagt
    35041 agaatgaacg acatttactt ggcctttttt taatttcgtt atgtttagca tataaaaata
    35101 ttatagagtt tacttacaat gcttaaaaca tatactgtat aatctgatca attttagcca
    35161 tgtcttgcaa tggtaagttt tctatttttt tgagttttcg ttccttaaaa tcaagagatt
    35221 ttaattgtgt aataattact tgtcctttta tatctagctc ttcaggtaat gagtaacgtg
    35281 tcggtaaatt ctttatagtg gaagtaattg gacatatgac cgaaaacatt gttttacggt
    35341 taaattcata acgagagacg actagtcctg gtcgtctttt ttgaatttct tttcctacgg
    35401 agggatcaaa atcaatccat acaatatcac cttttttagg aatataaatt ctttcttctg
    35461 acactataaa atttctctcc cttcaggagt taaatcttcc cattcgtctt tctcataata
    35521 ctcggcctct tccccaccac taaatggatc ttcaattttt ggaactaacg taattgttcc
    35581 atcatcagaa tacacaacga tatattcttg gttttctgaa ggtttctttc cgttatcaga
    35641 aggtaaagtt accactacag aacttccttg taatctagat tttgtaacaa gcattatcat
    35701 cactccctta ataaaagtat actatataac actaagtaac gcaaaattcc cctttgtaaa
    35761 ctatctagaa aattgttttg tttaaagtat atcttattgg atataaatag aaataaattg
    35821 tagccagttc attttttctt taactaaaaa aataatccaa gaaacattga acctatggat
    35881 ccaaaagcta cccaaatact atagctaacc ccccgctacc ttcaattttg cagataaaac
    35941 gctttgggag aaaatttcaa agacaacagg ccatcctatc atgcccgatt ataaacaaaa
    36001 agctggctat tccttttgct ctgacaaatt tcaattggga aagttcacga aactagcagg
    36061 tgaagaagtt tcaactgttc ggatcaaaga atgcccgctt caaatagaaa cattggttca
    36121 acgaatttca actagacaag actttgctat tgtagaacgt gagatcgtag ctatttttgt
    36181 agaagaaggg attttacatg atccaactca tatcaatgtg gataaatggc aacctcttat
    36241 ctataaattc agagaatata caactgccaa ccagtcgtta actttgaatt ttagattcca
    36301 agaattcaaa gagtcataat gataaacatc gttaggtata aataaaaaag actcgcagca
    36361 cgagtaaaaa acaaatagaa gctatacatt agaaaggtcg actgtgaccc tatagatgca
    36421 gtatatgcag cttatgagca tttcttctgt tctctttgtt tttgggatct gtgctgaagt
    36481 ctttttcgtt ttttgccgct ctttctttga aaaatcgatt atgttatacc ttctccatta
    36541 ctaattcagg catctgctga gtaatgattt ttcgcgcaaa agaaatatct gttacccaag
    36601 gttcgatttg ttcttcagtc aagacaagcg gcattcggtc atggattggt gcgactgtgc
    36661 ggttaggttc agtagtcatt atgattgatt ctgccatttt ttcatcctga tggctacgat
    36721 aaaaaccgcc aatatacact attttttcct tatttgaaaa cataaatttg tctttttctt
    36781 cattccactc attgggaaaa cacaacgatt ttgcaaaaat ggttgatgaa aggtcttttt
    36841 ttcttctact gtctctgcac gggcattaat catcaattgt ccttttttaa atccggtaaa
    36901 tccccacttc atgatttccg gagtgaggat gttttcttcc tcttttctta acgtcacaac
    36961 aagatttgac ggaaaaactt ctccagctgc taattctgct gcctgcttcg gttgtttcgt
    37021 ctgggcttct cgataataat tctgaaggag ctctgactct agatcaaaaa aataacgacc
    37081 acacatccta atccctccca atcttttttt ctatcataca ctgcaacaag aagttcgcac
    37141 caacaaaacg ctttcaattt ttgtagaact aaaaaagttg tgacaagtga caaactctcc
    37201 agtgaatggt attctcctgc caactcctcg gtcacaagtc acaatattca acaaacatga
    37261 gaagctgctt tttgaaattg ttccttgtga ctcggagtga aacggcaggc ttacgacctc
    37321 tgggtaaacg gtgttcaaaa gccagtttct cggtattaag ccaaatttat gcaaaaatgt
    37381 agaaagctat tttcacaaaa tttttcttaa tactcgaaac taagcgactt tttcacaacc
    37441 tcttccttaa acggtgttca aaagcttgca tctgcggtaa taagcccaac caaacgaaaa
    37501 atatgagcag ctatttttat ttggctgttc ttattacttg atgcagggca gctttttcac
    37561 aacctctcca ctaaacggtg ttcaatcagc taaccttcgg tattagctca aaaaacggca
    37621 aaatatgagg aactattttg ccgtttgttt ctctaatact caggtcaaag cgctgatttc
    37681 acaacctcta atacacggtg ttccagaagt agcttcttcg aaaaataagc cgaaatttca
    37741 caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct gaccacttct
    37801 gtcacaacct ctaattatta aagaaccttt tgcgaagtta acaatctttc tttgatcaat
    37861 tgaaaattct gcctaagtag tgatagatcc tgtgtgactt tcaacaataa gatacttccc
    37921 tggatttcag caatcaacgc tttggcttga cggtctgctt cttcatcgga cagtttttct
    37981 tcagaaagtg ccaggatatt ttgtttcgta tacttgaccc attgattgac taattctagt
    38041 agcaacagac ggtattcttc atccactgta ctcaactcaa taatcaaatt acctacagga
    38101 cagccatgat aagtgatctg tgtctcatga tcagcgaaaa tccagtccaa catttcttct
    38161 aatgcttctt ctggctgttt tccagcattt aagatgtctt cgaacaattc tgtctgccat
    38221 acgtccatat gcgcatggat caccgctaga caaacttctt tttttgaaga aaagtaataa
    38281 taaaattgac cttttcctgt atcagaagct gctagaatat ctcggattga cgtttcatga
    38341 tagccttttt tataaataag atctttggtc gcttccaaga tcttttcctt tgttttcaat
    38401 gatattctcc tttttcattt ctcatagtcc tatattatac agtaaattca tcattttttc
    38461 ttcttaatcg tttaaaaaag actgtgccaa attatctgac acagccctca ctataaaact
    38521 gttctcatat agctagatgt tcattgattc aagaactgcg aggacaaaag caattcctat
    38581 cttatgatag ttgctctaat acttcctctg ttgtcatcac ttgatctgca ataaagccaa
    38641 agttcgtcaa cgctgcatcc attgcttctt ggccaggagc accaattgca tctgtcgcta
    38701 ccacaacatt gaatccactc tctaccaatt cacgcatatg ggaatcgcta cacaagtttc
    38761 cgttcattcc accaagaatt actgtgtcga ttccattttt tctcaattgg agcgccaaat
    38821 cattgctttc tggtccaaag attttatgag gagagctgat gatcgtattt tcatccaaat
    38881 aaggtttcaa ttcttcgata aaatcggctc ctgaaccttc ttccactgat tcatattgac
    38941 tttttctagc aaacatctgc tgctcaagca tcatatgttc tcctgcaccg ccaaattgcc
    39001 atttatggtc atgtgggtaa aaataatgag gagaaataaa gagtttgtat cctttttctt
    39061 ttgcttgttt taccatttca atcatatttt cgatcgtatt gtatttttct aagatatctt
    39121 ttgtcaaacc aaagccaccg cctgctggtt tcaagaactc gacttgcggg tcagtgagaa
    39181 ctactgctgt atttttatta ttgaacatgg tggattctcc attcgttatt tattttaata
    39241 catcatttag agcttcactc attgtcggat gagaatagat ttgatctctc aataacgtat
    39301 aaggaagttt tccattcata gctagcgaaa tcaagttgat gacttcatga gaatcttccg
    39361 catagatact tgcccctaga atcaagtcag tttcagggtc gactaaaact ttgaatacac
    39421 ctttaggatc ttctaatact tgtgctttag ggacaccgct tgtcatatac ttgaataatt
    39481 tgtaattgac gccttgtgct ttggcttgtt tttctgttaa acctacattg gataaagtcg
    39541 gagtgataaa tacactgtaa ggcacagctt tccggttatt cgttgttcgt ttattctcgc
    39601 ccttcaactg atccataatg attcgataat catctagaga gatataagtg aactgcaatc
    39661 cgcctttgac gtctccaatc gcccaaatgt tgtctgcatc tgtacgaagg tattcatcca
    39721 cagcgattgc tccgcgatct gttagtttaa catctgtatt ttctaatcca agtgatgctg
    39781 tacttggttt tcttccagtt gcagccaaaa cttttgacgc ttggattgtt acttcttggc
    39841 catcttctgt aaaggtgacg gcagctgttg attcttggtc tgctacttga tctacagata
    39901 cacctagatg gaattcgatt cccgcatttg tcatgtcttc taaaatcatt tgcgcgatat
    39961 cttcatcttc acgtggaaga aattcagaat gggcatcaag aacgacaact ttagatccgt
    40021 attcattgaa cattgatgca aattccaagc caatatatcc agccccgatg atcactaatt
    40081 tttccggtaa ttgttcctga tccatcgctt gcgtagaatc aatcaagtag cgacttgtat
    40141 tcaatccttt gattggtaaa atgattggtt cagaaccagt attgatgaaa atccgttcgc
    40201 cttcaacaat cactttttca ccattattcg tcacttcgat ttgatggtta gaaagaaaac
    40261 gtgctgtacc gtccatcact gtcccagttg cctcatcgct gatcatatga taatttttgg
    40321 cgcgaagcat gcccgtcaat ttttctttcc gagcaacagc ctctgtaaag tcgattcctc
    40381 tttctccatt gaaaatcaat gatttagaag gaatacagcc gatgttgata catgttccgc
    40441 catacatacg tgttgacttt tcaacgacta aaaccgattc accttttgaa gctaacgcct
    40501 tcgctaaagt cttaccgccc tttccaaaac cgatcacaat attttgatat ttttccatca
    40561 tttttccctc gcttcttttt tacctaccga ttggtacaaa aatatgataa ccgataattg
    40621 tctattctcc aaatcatctg ctttatttgt caaaaaaaac cagacaaaaa gcggtccttt
    40681 cacgttttta gtctggttcg atttccttta ttcttctaaa caatcgttac ttctacatcg
    40741 atatttcctc tagttgcttt ggagtaaggg cagaattcat gcgcatcttc tgcaattttt
    40801 tgggcttctt cttcgctgat gccatcgata tgcacttcta atactacacc gatctgatag
    40861 ccgccatcat ctaaattata aagagagaca cgtgctttta ctgtggactc tgctgtcatt
    40921 cctgcttctt tgatcatatg ttgtaccgcc ccattgaaac aagaagcata acctgctgca
    40981 aataattgtt ctggatttgt tccttctgca tggattcctg gaggagtgat tttcatatgc
    41041 atcgagccat ttggtgcctc gacttctcca ttgcgcccgc catggttgat cattgctgtt
    41101 tcgtatgctt ttttcattgt actgctcctt tcgattgacc atttgctact tggctataat
    41161 tatagtgtat gacaagtaag gcgctttcta caaaaattct gcttattcga ataccagaat
    41221 gccgtcttct actatttttc caaaaaacaa aaaaatacta ctcgtgaaca acagcgtcat
    41281 atttgttcca aaataaatag caatcttttc tacataatct tttatatgat tgattttaag
    41341 atacatatat accagaaagt tgaccccata aaccaatact gttaaaaaaa taaccatatt
    41401 cgttaccatt ttttcctcct tttgctggtc tccctaccag cactcgattt aaccatacca
    41461 ctttttttgc cgtccaagca actagccttt caaaaagact ggtttattct gctgttaatg
    41521 attcaagatc agaaaaatgt ccgaataatt ttgctaattt tactaacgcc aacttgttct
    41581 ttccgaattc atcattttct atctgtaata ctagtaacgg ctcatgtaag cttaaacgga
    41641 tcaaaaacca gccgtttccg tatggctctt ctagatcata tcgaatacct tcttcatttt
    41701 ccgggtcgaa gttcatccct ttttcttctt ccaacagtcg cttcatttct tctaatatct
    41761 tgtttccttg ttcgcgtggt tcatcgctga acaattttaa tcggatttct tgtacttcta
    41821 cgggctgttt caactctttg atttgttcat ctaatgtgat accttttctt tttaattctg
    41881 gcaaaagcat caggatcttt gcgatgacat atgcaccatc atccagaaaa tagttttcct
    41941 tgaatgcagc gtgtccgctt gtttcgatgg ctagctgtgt atctttccca agacggttaa
    42001 gttctaatgc tttattgatt acatttcgat agccggaaat ataacgaact tggatgcctc
    42061 ctttttcttc aatgaatctt tgtagatgag aagaagtagg ggaattcgtc acgattcttg
    42121 ttcctggatg ctcttttaat acgattgtac ttaatactgc gatcaaatta tttcgattga
    42181 tcactgttcc agaagcactg acaactgcag aacgatccac atctgtatcg aaaatgatcc
    42241 caagatctgc ttcatttgct aaaacagcct gcttgatact ttccatcgct tctttattat
    42301 caggatttgg gatatgatta ggaaatcggc catctggttc caaaaattgg gaacctgttg
    42361 aatccgcacc taagctattc aatacttttt cagcaaagaa tccaccagca ccatttccgg
    42421 catcaacaat gattttccaa ccatttagtg gtttgctttc tagtgttcca atcccctttt
    42481 taatttttgt gactaaatct tgcgcataag gtgtcaaaag gtctgctttt tctacgcttc
    42541 cagtttgttc gctttttatt ttttgctgct gtgataggat aaaagcaata tcttcttttt
    42601 ctgctcctcc ttctgaggta aagaatttta ttccattata ataataggga agatggctag
    42661 cagtcagcat aaccgcagca tcgcacgaga actgttcaaa ttgagtggac ataaacatag
    42721 caggcgtagt agctaattcg aaatcgatga catgtatccc ttgttctttc agactttgga
    42781 tcaacgcctc tttcagtgct ggtccgctta tcctactgtc atgaccaatc ccaatcgtcc
    42841 attttttatt tggatcggtt gatttcttct ttttctttat ccagtttgct agtccccagc
    42901 cgatcttttt taccatgtct gtcgtcaagt ttacttcata tccttcaact ggtaatgcga
    42961 ttcctcgaat atccgatcca ttttgcagcg ctttcatatc tttcatataa aagtcctcct
    43021 catttattcc ctcatttttt ccagcttttc tgcaaatcgc tgtgcttctt cttctgagcg
    43081 gcaaataata atgaatgtat ctacaccggc catcgttccg acaacttcag ggtaagccac
    43141 ttcatctagc caattcgtta ccacatcggc accatttcgt tcagtcaata cgataaccat
    43201 gaactgaaca gactggatac gcaaaacctc gcgtctaatt gctgtacgca aacgttcttc
    43261 atttaaagaa acagatggct ggttaaataa tgtatagcgt actattttgt tttcattttg
    43321 actttttact aacttcattt ctcgaatgtc tcgagaaatc gttgcttgag tcacatcggc
    43381 gcctgcttca tgcagccgcg caagcagctc ttcctgtgtc ccaataggtt gttctgtaat
    43441 gatctggcgg atcagtgctt gtcgctgttt ctttttcata ttagacacct ctcaatgttg
    43501 attatagcaa aagataagta atatttcttc atattttggt attttttact tttatttttt
    43561 gttttcattc aggttgctaa cctttttcta ttttaacacg caaaatcgtc ttcatttttt
    43621 caggtgctga ttttcttgga tcgctgatgt aaatctcttt gtgttcttta gaagctcttt
    43681 catagccttc ttttgcgatg aatgcttcta atttctcaaa cgttgctggt tcttcggcat
    43741 agggcccgac gtgtaagatt tgggcacaaa gaccttcttc catctttttg aatactactt
    43801 gttctttcaa gtcttccgga agtttgctag aacgctgaat ggcttcttgt gctatcgctt
    43861 ctgtaacaaa gtcaggctgt cggatcatca attgataaga aaaatgttct tttttcatca
    43921 ctggttcatg caaatacttt tcttgcagtc cccattgtcc ttccagtgga tagacagtat
    43981 acatctgata atcaggaatc agccaatttt ttttaggcga catgcgtatt gcatagctga
    44041 ctgcatatag acaggctact cttcgtttaa agtcttcctg attcgggtcg ccgatccctc
    44101 tgatgctaaa gaatgatttt ttaggaacct ctagtatttg cgggcttttt ttcatactat
    44161 agctcttgtc tttacgccat tcaatttttt ccatttttct tcctccgcga aattccattt
    44221 agttatttat tatcatacct ctttttgagt gacttggcta atcgtgttga cactattttt
    44281 cagtttgtgc tagaataagt gaagtaaata aatcgtacag ataacacgtt tcggcgtgtc
    44341 gagagagagg cggtttctat ttttataata gaaatcactc tcttttttta cgaaattttt
    44401 tagaggtgat gtaaatgaca aaacaaaaac agctgctttt agtacctgca gtaattgcaa
    44461 cagggatgat gtcttttgcg ggcgtattga tcgagacggc catgaatgta actttcccaa
    44521 ctcttatcag acagtttgat ttaacgactg cacaagtcca atgggtaaca acgatttatc
    44581 ttttgatgat ttcgatcatt gttccgctgt ctacttattt gaatcgcaat tttagtctca
    44641 aaaaactctt tttagcttca aatctgcttt tcttggcagg tataatgatc gatttcttct
    44701 ctcctacctt catggtccta ttgtttggtc gattgctcca aggtgcagcg acaggtatcg
    44761 ctcttccgtt gatgttccat attatcttga catttgcccc cctcaatcga cgaggcgcga
    44821 tgatgggtgt cggtactttg acaacggcca ttgctccagc aattggcccc acttatggag
    44881 gcattatgac ttcacatttt acatggaatc atatcttcct gtttcttgtg cccgttttgt
    44941 ttctttcttt gattatcggc tggtttgcta ttcccgagat ggcagtacaa aaaagtggtt
    45001 atttggattg gataagcgtt ttaggaattt gtcttttgtt tagtggaagt ctaacatttt
    45061 tgagtacgtt gggaacagtt tccagctgga ttgctttaat catcggcggt attggctggt
    45121 tcctttttta ctatcgaagt aaaaaagtgg agcatccact gatccgactg tctattcttt
    45181 caaataaaac attccgcttg tttttgattg gcttcttagt ttatcagttt ttattacttg
    45241 gtgtatcttt tgtcttgccg aatttccttc agatcgttca aggaagtagt ccttttgtcg
    45301 ctggattagc gatgcttccc ggcgcagcgg ttggtgcttt gctttctcct ttttccggga
    45361 aaatgctgga tcaatatggt ccgaagaagc caatttttgc tgggctgatt ctttctttga
    45421 ttggttggct agcattattc ctactcatag gacacgcttc agtgggtgta ttgattgctt
    45481 gtcatgtgtt ttatatgatc ggtatcggat tatcttacag caatatgatg accaccggaa
    45541 tgaatgcact gaatgaagaa ctacaaggag acgggaacgc aatgttcaat accttgcagc
    45601 agttttctgg cgctgtggct acttcattag tagcggtcat tatcaattac gtccagcatc
    45661 atacttccca taactatgaa gtgtctacta cattaggatc aaaagcagca ttaggcgtct
    45721 tgttgctgtt gcttctcgta agctttgctc gattcgccta ttatctgttc tttgctaaaa
    45781 aagcgtagat tccatatacg gcaggtgttg catctgccgt ttttttgtgt gaaaatggtt
    45841 gtttgtaaaa ggaggctttt ttatggaaaa aattgccatt atcggtggcg ggatcattgg
    45901 tatgacccta gccagttact tagatacatc aaaattcaat gttgctttat ttgatgaagg
    45961 gacaggacag gcaactaaag ctagcgctgg gattatctcc ccttggttgt cgaaacgcag
    46021 aaacaaacaa tggtatcgtc tggctaaaga cggcgctgct tttttcccta aacttataaa
    46081 agatttccaa cttgatcaaa cgatttacgc acaatcaggg acacttttgc ttcgacctga
    46141 aaaagattta gctgaattgg ctgttcttgc cgagaaacga aaagaagaag cgccagaaat
    46201 tggaaacatc gaatggcttt cacctgaaca gacatctcaa gcacttccgt tattgaaacc
    46261 agcagtttca ctgcgtatca gtggtggtgg tcgtctggat ggaaaagcat atttagaaca
    46321 tcttggtcag cgtttagcac aaaaacaaat ggagcagatc caggcaaaag tcactttgca
    46381 taagaagagc gattcttggc tcatcaaggg accgtttgga gaatacacag ctgatcgtgt
    46441 aattttgaca cctggcccgg cacttaagcc tttattacaa gaattaggct atgctgcaga
    46501 tatacgtccg caaaaagggc agctcttagc atttcagaca tcttataaga tgagtcaaga
    46561 ctggcctgtt gctatgcttg acggagaagc tgatttcatt cctttcatgg atggaaagat
    46621 ccttttaggt gctacccatg aaaacgatca aggctgggat ttggctccta ctagcgaagc
    46681 ttataaggga ttgactaaga gtacagaaca gttcttgact gatccagatc agataaaaaa
    46741 ctggccatac gagttccgtg taggtacccg tgcttatacg tcagattttt ccccattttt
    46801 cggcgtactg ccagatgatc caagcttact ggctgctagc ggtctaggct cttctggctt
    46861 gaccacaggt ccttatatcg gctatctatt agccaacttc ttaaatactg gtcattggcc
    46921 tacggaagat tatcaaaagg acatctccac ctatattacg aaaaatccat catagaaaaa
    46981 cagctttttc aagtaaggat cccgagcgat attgcgcatg gattacttct tgaaaaagct
    47041 gttattttag ttcaatttct gaatcaaatt ctccaaactt tcttttgctt catctggcaa
    47101 gagatctttt cctatctgag cttcaatgaa tcgtaaacga atatcaagtc gttgtttcac
    47161 cagattttta taggacgtat cctcaaaaga aacaggaaaa tctggtatag gtaaatagtg
    47221 gatgtcttca aatggaccaa acgacttgaa ttctgccgtt tgttgcacga ttctttcaac
    47281 gattgacaat gtcgtttcag gtttgatttt tttatcatcg aaatatccag tattcaggac
    47341 atagcaggct gtttgctgtt tcaaaaacaa ctctcgaaaa gcttgatagt cttccctaag
    47401 aggatagaca cggaaaggat tagcaaatgg ttcaatgact agctcatcta gctgtctttt
    47461 tgtagtgata ttttccgcgt ctgatcgttt tgttgctaat gttgcaccaa aagacgctgc
    47521 taaaactggg tcattgatct tgataattgg cggaagcgaa tcatctttca tgatccaaaa
    47581 aacagcatcg atcttttcgc taagatgatc gactcggtcg ggtgtcgcat aacgtgattt
    47641 gactgtccgc ccatttccgt ttcgtatatc tcctgttact aggacttttt ctcctttact
    47701 tgtacatgtc acgcccacat tctgacaagt aaggaaagaa gaaatggccg gatcatcaga
    47761 cggatagtct tgtgttttat caaagtaaga aggttccaag gcagtagcaa aaccattttt
    47821 tcgagaaata acgaaagcat cgtcatgcaa gatcgaaaca gagtgacctt ccgtatgttt
    47881 tgctaaggta atcgttgatt ttccagaacc ggacaaccca aatacagcca tcgtataggt
    47941 ctggtcatta ctagcatatt gtttcatccc accgtggcag gcaataaagc cattgcgatt
    48001 tcccaatgcc caagcaagcg tcaaagtcgc tttttttaat tctccaaagt aacgtaatcc
    48061 tagcacagcc gctgtattat ggagagcatc aaacaaaatg agtccatttg gaaatgtttc
    48121 atgtgtccat tcgggatcac aaaagatata aagatctccc tcatcaaagg aaacagactt
    48181 ttgataagtc tctaagatct tcgaattcgc tggctgaaaa ttcagcaaat aagaatacaa
    48241 attgttctca aatccttctg gaatcagcaa atgactttgc acagaaaatt cttcagatag
    48301 gccaacgatt acttttgtat ggtaaaactg gcgcttgcga ctttgataca cagcttctct
    48361 taaaattttc tcgtatttgc tttgttcctt gtctaagtcc tcaaagatcc gccgagcact
    48421 tgctgttctt cccacaatgc ttccatcatt gaatactagt gtcctaacat cagctggtaa
    48481 atctagttct tcagcatgtg agattgttaa atctgtgatg atcgttcctg gactcccttt
    48541 tgctagttga taagctgtct tcctatcaaa aacttcatga acattattac cgtaaaatgt
    48601 cgtttctaca atcgatcgaa tactggataa cagtggattt ccacttgtga tttcgtttaa
    48661 ttcgagactc tcttttgtac tcatggctcc tcctcattcc ctaaacaaaa aaacgttttc
    48721 tttattatac attattcgag tttttatttg tactgctgcg ctgtgggaag caaacgagtt
    48781 atttttcaca caaaaaaacc gagaacttga ataaacaagt ttctcggttt catcattttc
    48841 cttttatcgg cttagtacca gccgtttgct aaccagaatg ttttagcagc atcccatgaa
    48901 ccataacgag atgttacata ttgttctgct acacgttctt gattggcagc tgaatagtcg
    48961 ccgtttaagt atgaagcatc taattgataa cggccgatgt aacgtccgtt agtagctgtg
    49021 tatgaaccgc ctgattcttt ttgtgcgatc cattcttttg cagagcttga agttggcgct
    49081 gttgcagcag ctggggcagc aggagctact tcaactgttt caacaggtgc aacgtatgta
    49141 tgttcttgcg ttgctgtttc agttgtagat gctgtatttt ctgttgtttt gttttctgtt
    49201 gttgctgaag aatcatttga agttgggatt gttaattgtt caccaacata aatgcggttg
    49261 atgtttgcga tcgaattttt ttcagcaatt gcatcgatca ttgagttgtc tcctgcaaat
    49321 ttttgtgaga tcttagataa tgaatcacct gattttactg tataaacttc atcagcgtga
    49381 gcatttgtag ttcctacaaa cattgcagta gcaccagcag caaaagttgt acctaaaaca
    49441 attttcttaa atgaattcat attaaactcc tttttttctc cgttttttat tctttcgacg
    49501 ctattaactt tatcatttag aaatatttca taggtaaaag aaacatgaca tttaatgaca
    49561 aaataacgaa ttatttaata tttgtaacat ttaaacaaat atttttttga tacaaaacca
    49621 taaaagcctt gttgtataag caaagtaatc gtttttctat gtttttttat ttttgaatga
    49681 aaaacgcaga ttctgtaaca ttcactgcaa taatccataa aaaaaagcaa aaaaattttt
    49741 gatttttatc aaattctctt aaaaaaatgt aaaaaataca aaaaaaccag taattgttac
    49801 aacaattact ggacaaaaac tttgaataat gttaactatt tttttatttt aactttctcc
    49861 gcaataattt ctgggcatgt tccaattcgt ttataacgac ttcttctgtt tctttagcta
    49921 atatttcatc taatacatca agccattttt ccggttcttt tgttcctaga cgtccaatag
    49981 cccaagctgc tgttcctctg atgacagggc ggacatctgt taaacattct gaaatctcag
    50041 gcaatgccgt tcgatcacct agattagcta aagcaatcaa tgcgtttctc tgcaaaggtt
    50101 tcttcccacg ccatgaacca gctaaatgcc caaattgctg tttgaagtct ttattagaca
    50161 tcgaaagcat tggctttaat tttggatata tttcgtctac ttttggttcc atctcttcat
    50221 gaaaatgaaa atcttttcct tgattgtaag ggcagactaa ctggcagata tcacatccat
    50281 aaatgacatt tcgcattttt ttacgatatt cttccggcat catccctttt gtctgagttt
    50341 gataagacaa acatcgctgg gcattcattc ttccgtcacc aagcaatgct tttgtcggac
    50401 aagcagtcac gcagcgcata cagtcaccgc aaccaaattc tcctggttta tcaggctcaa
    50461 atacaatatt agtaacgatc tcaccaagat agacaaatga accgaactct tcagtgatca
    50521 acaatccgtt tcgtccaata aatcctaaac cagctcgctg tgctacagcg acatcgatca
    50581 gttctccagt atctacttgc ggagctagac gccattcctc ttctttttgc catttttctg
    50641 ctcttgtttg gatgaattcg atcaatcggt tcaaacggtc tctgagtata tcatggtaat
    50701 cgatccccca agaagcacga gcaaactgcc cgcgtttttc atccctaggc acttcttcat
    50761 ggatcctagt aggatacgca agtgcaatgg aaatgatcga tttcggctga tcaaatgtca
    50821 tttctggata aagacgctca tcgatatttg gatgttcaaa gccagaagta tggccagctg
    50881 ctttttgttc ttccaacgat tcttttaatg aatcaaaagg ttccgccgtg gtgaacccga
    50941 ttttgtcaat tcctaatcgt ttgctttctt gtatgatttc ttcttttaat gtcatggtct
    51001 tcctcgcttg ctgttaacgg ctgtataacc cataatatag tttttctttt ttcagctgga
    51061 caaactggat ctgctgatcg gcaatcttct tttcttccat ccattttttt cttgcagcaa
    51121 atacttccca ataatttgtt gaaattaatt ttcttttgtt atctaatgca ttaaaaaaat
    51181 tcaatgaaac tggttttgta cttaacagtt catggagcct tacctcttcc catggcgaaa
    51241 actcagacag atcgcgggaa tacaatactt cttcatagag atttttttgc tgtgtgtacg
    51301 tgaatgtttg cgggattttc ccaggcctag caatttctac tagacgatta taaaacatat
    51361 tcattaattt gctgttggca ataaattgac ttttataata ggccgactgg atctttttga
    51421 ttactccttc tgctttgatg actgaaaata atgcaggcca tgctttgacg gttatttcgt
    51481 cgttttgttt aactaatacg ccaggtgtga agccgactgg agaaaggaac acaaaataac
    51541 cgataccggt attttcatct aaaggctgaa attcatcaaa caaccatttg cctatgtaca
    51601 gctcttcatc tggttctgtt gtctcatttt gatttgctat gaataattta gctaattctg
    51661 cttcaagaaa ttgaaggtct tgatccttgt cggtattttc ctgctggctg atcaatcgaa
    51721 agacttcttc tttaatcgta tatttatctt tacgtgtaaa attcatagcc acaccttcct
    51781 tccttactct aactataacg gaatttcttc aaaaaaggta tctgtacgac gaaaaacagc
    51841 ataatttttt ttcatatctc ttataaaaaa tgcaaggtct gctcctcaag ctagaccttg
    51901 cacttttcag ctttcttttg tttgtgacaa accttcatgg atcgtttcaa tattccattt
    51961 catcatctga tagtaagaat ctccttgttc tccttctttt gctatggaat cagtgaacag
    52021 tttatcatag attttcaaac ccgtttcttt tgctacccgt tccatgcttc ttgagtctac
    52081 actggtttcc acgaataaaa ccggtacttc ttttgctctt atctgatcaa tgatcgcttt
    52141 catttgatca ggcgtacctt gactttctgt attgatctcc catatataag ctgctggcaa
    52201 atcatatgct cgtgaaaaat acttgaatgc cccttcactt gttactaata attttttgtt
    52261 ctcttcgata gaagcaaaac tttccttcgc ttgtgtatct aattctttta gtttttccac
    52321 atatgcttct gcattttttt tatagagtgt cgcattttct gcatcttttt cagagaatat
    52381 acgtgcgatt tcctccacat attttattcc gttagatagg tctagccaag catggggatc
    52441 tgcttttgta tgttcttcac cgctagttaa ataaagaggt tctacatttt tgctaactgc
    52501 aaaataatct tttccttctt cttttttagc cgtttacatc aagttatcga accagctgtt
    52561 acctgtttca agattcaaac cgttgtataa aataacatct gcatcgcttg cctttttgat
    52621 gtcttctggt agtacttcat attcatgcgg atctgttccg actggtacga tactgtggat
    52681 atctatttga tctgttccga cctcttttgc catgtccgcc aagatcgaat tggtagccac
    52741 gactgacaac ttttctttac ttccttcatc cgcttggtca gaagcctgct ttccgcaacc
    52801 ggctaatacc aagaaactaa ctgccaagat taaaaagagt gatttttttg ttttcatcta
    52861 tctgcttcct ttctgaaata aaattccttt tgttggagaa aataaaaaag caaggataaa
    52921 aaatgcggta catgctaaca cgatcgtagc tcctgatggc caattgtaac tataactgaa
    52981 aaacacaccg acaactgcac ttagcatacc gattcctgca gctgtaatga tcattttcag
    53041 taaatggttc gttagcaagt aagccgtggc ggctggtgtg atcaacatgg caatcaccaa
    53101 gattgttcct actgtctgta aactgactac agccactaat gtcaaaaaga acatcaaaag
    53161 ataatggatc agcgatgtgt tcagcccata agcttttgcc attgtcggat cgaatgatgt
    53221 gatcttcaat tctttataaa agaaaaagac aaatatcaag acgattccac taacgagtgc
    53281 tgtcagcaac aaatcgcttt ccctaacagc taagacattc ccaaataaaa tatgatacaa
    53341 atctgtcgca ctctgggcat atgaaatcaa gataatccct aatgcaaaaa aggagctaaa
    53401 gacaattcca atcgctgtat catttttcaa tcggctccgc tgagtcacga aaccaatcac
    53461 tgctgctgtt agcatcccaa aagcagtggc tccaaagatg taactaaaac caaacatata
    53521 agaaatggct acacctggaa gaactgcgtg agagatagcg tctcccatca aagacatccc
    53581 tcgtaaaata ataaaagaac cgatgactcc agaagcaagt cctacaagca tggaagtgac
    53641 caaagcgtat tgcaggaatt gataattcat taatccatca ataaaggatt ggatcatttt
    53701 ttctctcctc cttttactaa atgtctgatg atctcaccat aggccaattg aaggttcttc
    53761 gatgtaaaga cttcttgtac tggaccggaa gcgatcagct gtttatttaa aagaataacc
    53821 tcatcgaaat attcttctac tttatgaaga tcatgatgga cgatcaaaat cgtttttcct
    53881 gaattcttca attcctgcaa gatgtcaaag atctttcgtt cacttaacgc atcaatccct
    53941 acgaatggtt catctaaaaa gatccattct gctccttggg ctagagctct tgcaataaaa
    54001 actctctgaa gctgtccacc cgatagttcg ctgatctgtc ttttggcata ttcttccatc
    54061 cctacttttt tcaaagcttg tcttgcacgt tctttttctt ttttcccagg tctttgtcca
    54121 attcgtaaag atggatatgt tcctaaaagt acaacgccta atacatcaat tggaaaggaa
    54181 agatccaatt cacttcgctg ttccacgtag gctatttttt tacggactga gtttaccgac
    54241 tgtccagaaa aggtgacttt accagtagta gctggtatca actctagcaa agatttcata
    54301 aatgttgatt ttcctgcacc gtttggtccg ataataccgg taattttttg tggatttatc
    54361 gtcaagttga tagttttcaa aacagttttc ccttgataag cggctgaaag gtcttgaatt
    54421 acaatggccg tacgttccaa atcttacact cctttttagg tttacctaac tttttattta
    54481 aatatagttt aactaaaatg gaaagcattt tcaagtagaa tgatgaaaaa gtttttttcg
    54541 aattttcctc gcattttatg aaaattttct gtagaatcac atcaagagtt caataaggct
    54601 aacctaataa tgaaaaacat gtgttgaaac gtttgattat tttttcttgt tgactcaaca
    54661 acgaaaggag tttttgtatg gaagaagaaa agttaactcg aagtcttagt gcccgtcata
    54721 tccaaatgat cgcactaggt ggaacgatcg gtgtcggtct gtttatgggt gcctcctcaa
    54781 ccatacgttg gacagggccc tcagtgatgg gagcctatgc gattgcagga ttctttttgt
    54841 atttgattat gcgtgcttta ggcgaaatgc tttacgttga tccttcgact ggttcttttg
    54901 caaattacgc gagcgagtac atccatcctg tggctggcta cttgaccgct tggagtaata
    54961 tttttcaata tattgtcgta ggaataagtg aagtgattgc tgtaggatct tatatgaatt
    55021 attggtggcc tgatttgccg gcaattattc ccggaatcat tgtcgtcttg tttcttatgc
    55081 tggcaaatct tatttctgtc aaggcgtttg gcgaattaga attttggttt tcgatcatca
    55141 aagtcataac gatcattttg atgatcattg caggtcttgg ggtaatctta tttggatttg
    55201 gtaatcatgg tcaggcagta gggatttcaa atctttggaa aaatggtgga ttcttcactg
    55261 gaggcgtcaa aggatttttc tttgcattat cgatcgttgt tgcttcctat caaggaatcg
    55321 aactgatcgg aatgactgct ggtgaagcag agaatcctaa aaagacgatc attgaagctg
    55381 tccagtccac tatcggtcga atcttgattt tttatattgg tgctattttt atcattgtga
    55441 gtatctatcc gtggaatcaa ttgagtgaga ttggttcacc ttttgtacaa actttttcta
    55501 aagtcggcat tacatttgct gcaggactga ttaattttgt cgtgattaca gcggcattat
    55561 caggttgcaa ttcagggatt ttcagcgcaa gtcgtatggt ctatacactt gccataaatg
    55621 gaaagatgtc taaaaaattt ctgaaactat ctcgtcacgg tgcgcctttt tatcctgtcg
    55681 tagcaatctc aggtggaatc ttaattggtc tgatcttaaa ttatcttcta ccaatgttca
    55741 tcaaccagtc agaaaatatt ttcgttttcg tatacagctc aagtattttg cctggtatgg
    55801 ttccttgggt agtgattttg atcagcgaga ttcgcttcaa aaagaagcac gcagataaaa
    55861 tgcatgatca tccttttaaa atgccactat ctccttatac gaattatgtg acacttgctt
    55921 ttttagctat cgtattgatt ttcatgttta tcaatcctga aacgagaatc tcattgatta
    55981 ttggactcgt tttcttgctt tacatgacga tccattactt tgtacgcgaa aaaagaaccg
    56041 gaaaataaaa aaagaacgaa gcttcacctt agtggaagct tcgttctttt ttattgcttt
    56101 tatcaattca attttagcgt ctcaccggga gtcaggaaat aattctccat gctcatccca
    56161 ttcagcgaca agatcgtttc tactggtacg ccagttcgtt cggctatttg atttggacct
    56221 tctccttcca aaactacggt tgtcgcagcc tgtgaagtcg cgctgttggt attagtttca
    56281 gaggaatctg ttgtgtcttg tgttgttcga gcttgcattt cagaagcttc taccgactct
    56341 gctgtctcag aatcagaaga tgttgtgtct tgtgtgcttg ttgactctgc ttgaagagag
    56401 gcgctagtct gcaaataaat atcggaaatc ttagcgacat gattcgtata attagccgat
    56461 aattgattga tcaaagtatc taagtctaca ccgtctttat tttctgctgc ctgatacgct
    56521 gcacgtaatt ttctgatccc ttcgtcggag attgcttgaa gctcacgtgc tttttggtta
    56581 gcaactgctg ataaaccagc tattccctct tgatttccct gaatttctgt ctggtattct
    56641 tcaatcaatg caggcgtctt ttcttcgatc tttttcgaat aatcatttac gattgcttga
    56701 agttgctctg gcaaaccatt tgctgttttt tcttcagaag tttgtgtctc ttttgtttta
    56761 gttgatgact cacttgtttg tttcgtctct gttttctttg tcgttgtttc cgttatggtc
    56821 gtacttttcg cttctgacga attttttcca tgaaaatata gacccgcaac tcctcctgct
    56881 atgatcaaaa acacggcaac tgctgcccca atcatgatca tccgcttacg agctgcctgt
    56941 ttttgctgtc ttcttcgggt catccgaaca ttttctcccc actcattttc atcatacatt
    57001 tttttcacca ccaattttta tgtataatag cgttatcaaa cgcttcatat tcttattgta
    57061 gcaaataatt gtcgctgtgc acatttttat ctttgttatt tataagaaaa tttcaccagt
    57121 tgagatgatt ccaagattgt ccgtcgattt ctccttgcag ctgcattgtt cgttcgtcta
    57181 tctcagccat cagtttcttt atttcatata agagcgcacg gtcttgatat tctgattttt
    57241 cgcttaattc atctaattgt tggatcagcc aatcatttgt cataatgaag ttcctttcat
    57301 ttcttgcagt gtaaaggtca agtcttcgat ctgctctttt gcctcagtca gtgcttctac
    57361 gatatatgct tgtttttcag attcttcttc ctgcattttc tgattttcct gtactctttg
    57421 aataaaccag tcaatccgct gagtcagcga tggtttgcct tccaatgaga gatactgctg
    57481 ataagcaatt agcttctccc aacgtttttc ctgggataaa tacataaatt gtgctaaaac
    57541 gaatggcgga agataggtca tatggaattt atttgcgatt cgctgatacg gcctcaaaaa
    57601 ttcggaaatc gtatattctt cttttcctcc agcttggtat tctttttccg ccacacctgt
    57661 tgtcaatacg attcctagtt ctttcccttt taatacatgt gctgctcgtt ccaagacatt
    57721 atcttgccaa atttttaaat gagcaggaga actataccag taaaacggaa actggaaaat
    57781 gatccgatca tgctgggcca agagctgtag ttcagtctct atatctattt ttccgtctgg
    57841 ataacttgat tccaaatgat gccaagtagc tggtaaacca gcagaagctt ctttgaaaaa
    57901 ttgctgattt aaagattctt cgatcgttgg atggctaatg atgataagtg tacgcatccc
    57961 ttttcctcct ttttagtctt cgctttacag tgtagcataa ccgccacaag tttcttttgc
    58021 cgatgcttgt cattttaacc agactaatca ggttgtccaa gaaactgcgg tttgtttttc
    58081 caactgtttt ttcaaggtat ccaaagcaat attcttaaaa ttttcgtttt tcatacgttt
    58141 acgatagttc gtagccgttt ctccggtact ctttttgaac attcggctaa atacgactag
    58201 actattgaac cctacttgat aggcaatact ttccacggat tcatccgtca gagaaagaag
    58261 aaacgcccct cgattgatcc gtaccagtat caaatattcc ttgatactgg tacccatatg
    58321 atttttgaat actcgcgaca aatggctccg attgaccgct aaatgctggg cgatttcctc
    58381 aacagacaat ttttcagcat aatgtgcctc gatgtatttg actgtttcaa cagctaaaga
    58441 ggaatgaacc ttttgtacac caccgctgac ctttccgcca tcttttaaaa ggactgataa
    58501 aaaacggtag gttaatgctg ttaactgtaa ttcattttcc aaggtttctt ccgtatcttt
    58561 catgcattct aaaataatgt cgatatattt ttgtatgtca gaagagacca tcgtgtattg
    58621 gtcttctctg aaaagcgact gccgaatgat ttcttctgca gcactcccac caaatgaaag
    58681 ccagcaatac atccacggat cttctccatc tgataagtaa aacgtcgagt ctcctggacg
    58741 aatcaagaac agatcacctt ttttcaattg gaattgttga tttttcacat gataagatcc
    58801 tttgccttcc atcacgacat gcaggatgta atcattgcga atagcaggac caaaagaatg
    58861 aaacggcatc gttttagaga aaccacaaaa atcaaaatac aattcttttt ctacttgttg
    58921 atgttccttt tttaaaaaaa tcgattgctc cacgtctatc cctccttact cctttagtat
    58981 aatgcaacaa aaagttaaat aaaagtcaca gaaatatatt aaaaaggaag cgatttcttg
    59041 ttaagtttaa gtcattaaaa gatctttgtt attcgttgta accggtttac ttagtattat
    59101 atattgaaca ggagaggaat acagattatg aaaagcaaaa tgatccaacg tgtgtcctac
    59161 gctttaggcg cttttggaca cgacacattc tatgttacat taagcactta ttttatggta
    59221 ttcgtgacaa gccagatgtt cgcaggaaca gataaggcaa cgaatgcaaa aatgattgct
    59281 acagttacaa gcttagttgt aggtatccgc ttagttgaaa ttatttttga tcctttgatt
    59341 ggtggcatca tcgataatac tcgtacaaaa tacggtaaat tcaaaccatg gttagttatc
    59401 ggcggcgttg ttagttccgt actcttggta gcaatcttta ccaatttctt tggcttagct
    59461 actcataata cgactttatt tatcatatta tttgcaatcg ttttcatctt attggatagt
    59521 ttttattcat ttaaggatat cgctttttgg tcaatgattc cagctttgag tacggaaaca
    59581 aaggaacgtg aaaaatttgc tacgtttgct cgtttcggct cttctctagg tgcaaatggt
    59641 actactctag tcgttgtccc tatcgttact ttctttacct atcttgttac tcataaacat
    59701 attgaaggcg cttcaggctg gttctggttc ggtgtgattg ctgctgttat ttcaggcggt
    59761 actgcgatta tcactgcctt gggcacaaaa gaagtcgata ctgcgatccg tcagcaaaat
    59821 gaaaaagctg ggatcaaaga tgtgttcaaa gcagttgctc aaaatgatca gttgatgtgg
    59881 cttgcccttg cttatatcgc ttatgcgatt gccaatgcag caacaactgc cgtattattc
    59941 tacttcttca aatatgtact tggccaacca actgaatttt ggatcgttgg tctagttgct
    60001 gccttacttg gtttagtagc tgttccacta ttcccaatgc ttacacgcgt catctctcgt
    60061 cgctacgttt accttggagg gatcgcaatg atgatttctt cttacttttt ctttacgatc
    60121 gcaggttcaa gtttgccaat cgttatcatc gggctagtat tgttctactt ccctcaacaa
    60181 ttgattttct tatccgcttt gatgacgatc acagactctg ttgaatatgg tcaatggaaa
    60241 aatggtatcc gtaacgaagc tgttactcta tcaattcgcc ctttactaga taaaatcgct
    60301 ggtgctttgt ctaacgggat cgtagggttt gtcgctatcg cttctgggat gactggtaat
    60361 gctactgctg ctgatatcac tgctcatggc gtaacgactt tcaaagctta tgcattctat
    60421 gctcctgctg ctttgatgat tttctccgct attatttttg cttggaagat tacattgaca
    60481 gagaaaaaac atgcacaaat cgttgagaaa ttggaaaaca aattggctcc agctgataca
    60541 atggaagatg aacttcacga tgcagtagtt ccttcccatt aagaaaggat cttgaaaatg
    60601 aagattacag aaaaagattt tggccaaggt tatcacttga taaccttgga gaacaaaaac
    60661 aagctagcac tttctatctc tgatttaggt gctagaatcg tcagtttaaa atcaaatgat
    60721 cgagaattag ttttgggatt tgacaccgct gaagaatata tcgaaaaaga tccgtatatc
    60781 ggtgcttcta tcggtcgcac cgcagggaga atcgaaaatg gccgcttttc tctcaatgga
    60841 aaaacttacc aattagccac agatccaaaa actggacata atctgcatgg tggtgctcct
    60901 ggatttgaat taaaaaaatg gtcttatgtc attttgaatg gcgaaaatga agcttctgtc
    60961 atttttacta ctacaagtcc cgacggagaa catggttttc caggtacaat ggatgtggaa
    61021 atccgctata ctttgacaaa agataatatc tggcgagtga cctctcgcgg caccagtgac
    61081 caagatactt tattcaatcc gacaaatcat gtttacttca acttgacggg agatgcttct
    61141 cagtcaatcg atcaacatga gctttggctc aatagcgaag cttatgctcc tttgcgaaca
    61201 gatagtattc ctataggggt aaaagaaaat gctgcaggaa gtgctttcga ttttcaaata
    61261 cctaaaaaat tagcgtccgt ttttgctagt gatttggatc aaaaaaatct tgttgacgga
    61321 atcgatcatc catttttctt aaaagaaacc ggcttgggta aagaagccgc tcgcttgact
    61381 agccccgata aaagaatcca agtagatatt gctacagatg cttctagtgt ggttattttc
    61441 actgcaaatt tcggcacaga aacaccagaa atgcgcaacc gaaaactggc acatcacggt
    61501 ggcatcacat ttgagactca aacagctcca ggtgcagagc gcttctcagc atttggttcg
    61561 attcatttaa aagccggatc agtatttgaa acagtaacag aattcaaaat caaaacaaga
    61621 aaggaataac tcatcatgga aatcaaaaga agcttaaaca caaaatttgc cgaaacattc
    61681 ggacctaaaa aaactacaca atacttctca ccaggacgca tcaatttgat tggtgaacac
    61741 acagattaca atggaggcca tgtcttcccc gcttccatca cttatggaac gcaaggtgta
    61801 gcagcacctc gagacgataa taaaatatta gtttattcca caaactttga cgatatcggt
    61861 gtcattagtt ttactttaga tgagctagaa tatgataaaa aagcaaactg ggcaaattac
    61921 gtaaaaggaa tggtccttaa attaaaagaa gctggacact caatcgatca tgggtttgag
    61981 ttattagtgg aaggaacaat ccctaatggt gcaggacttt ccagtagcgc ttcattagaa
    62041 ttattagtag gtgttgtatt agaagatctg tttgatttaa aaacagatcg cttggaacta
    62101 gtccaaacag gtaaaaaagt agaaaatgaa ttcatcggtg tcaattcagg tatcatggat
    62161 cagtttgcca tcggcttcgg tgagctagat catgcaatct tattagatac aaatacgctg
    62221 aaatacgaaa tggttccagt gaaactagat ggttatgcaa tcgtcatcat gaatacgaat
    62281 aagcggcggg aattggcaga ttcaaaatac aatgaacgcc gtagcgaatg cgaagaagcc
    62341 ttggcacgtt tgcaaaaaac tttgcctatc tcttctttag gagacttaga tgaagaagaa
    62401 tttgaatcaa ctattgacca aatcggcgat gatacattga tacgcagagc tcgccatgcc
    62461 gtttctgaaa atcagcggac tttgaaggca aaagctgaat tagaagctgg gaacttagaa
    62521 gcatttggtc aactgttaaa tgattctcac cactctcttc gctatgatta tgaagtaact
    62581 gggatcgaat tagatacact agtagatgct gctcaaaaac aagaaggtgt cttaggtgca
    62641 cgaatgacag gagctggatt tggtggctgt gcgattgctc ttgtcaaaga agaaaatata
    62701 cctgccttca aaaacaatgt ctatgatgaa tacatgaaag ttgtcggcta tgctccggaa
    62761 ttttatgttg cacacattgg aaatgggaca acaaagatcg atccagaagc tgttcatgtt
    62821 tgataaaaaa atcaacgatc tcagctaaaa acaaatagat aaaaataacc tctcagcaat
    62881 ttccaaatgt gagccttttg ctcgtatttg aaaattgctg ttttttattg acacggaaag
    62941 agaacgtgtg ttctaattgt gttgaagagg tgattgttat gtgggcgaat caaaatccgg
    63001 tatttgttta tgaaaaagaa ccttcaagag atattttatg tattgactgc aaatcttttt
    63061 acgcctccgt agagtgcgtt gaaaaggatc ttgatcccct tacaactaaa ttagtagtca
    63121 tgtcctatcc gtccgattcg acagaaacac ggggtagcgg attaatcttg gcttccagtc
    63181 ctgcagcaaa aaaagcttac ggcatcacca atatcagccg tgccagagat cttcccttcc
    63241 cctatccaag tgatttatat attgttgccc caaggatggc ctattatatg gaaaagaaca
    63301 gagaaatcaa ttctatctat aaaaaatatg cagacgaagc gaaccatcat gtctattccg
    63361 tcgatgaaag cttccttgat gtaacaaata gcatggcact ctttggtaaa acaaatgcgt
    63421 acgacatggc taaactgatc cataaagatg tgtttgagca gaccggaatc tacacgacta
    63481 taggaattgg cgataacccg ctacttgcta aactagcctt agacaatggc tcaaaagacg
    63541 gaaagcaaat gtttgctgaa tggcgttatg aagatgtacc agaaaagtta tggaaaatct
    63601 cagatatcac tgacttttgg ggaatcggca aacgaacagc aaaacgtctg aaacaaatgg
    63661 gtatacattc tgtttatgat ttagctcacg cggattatta tcacttgaaa agcaagctag
    63721 gggtcatcgg tactcagctt tatgcccatg cttggggcat cgatcgaagt tttttgggac
    63781 aagaatatac accaaaatca aaaagtatcg gaaatagtca aatcctagat agagattata
    63841 caagacgaga agaaatcgag atcgttatca aagaaatggc cgaccaagtc ggcactcgct
    63901 tgagacgatc tgcagcaaaa acacaagtag tcagcttatg ggtaggatac tctttaggct
    63961 atcttgatcc aaatggcaag accgggtttc accagcaaat gaaaatcgaa gcgacaaatg
    64021 ctagcagaga tctagcagat gctttattga ccattttcca ccagcattac cactaccagg
    64081 atattcggcg tgtaggcgtg aactgttccg acctcgtata cgcgacaggt ttacagctta
    64141 acctttttga agatcctgaa aagcagataa atgaagcgaa agttgatttt gttgtcgata
    64201 cgattagaaa aaaatacggc tttcaatcaa tcatccatgc gcatagtctc ttgcaaggag
    64261 gacgcgccat cgcacgtagt tctctcgttg gcgggcatgc aggtggtatg agtggattag
    64321 aaggtggaaa agatgagacg gacagcaaaa aaattcattg actataacga gtatcgagat
    64381 cggccatttg gattaaaatg ggggactgct tttgcgatgg aagaactagt caacggtatc
    64441 aaaaaaatga agaagaagca cgcaaacagc ctcttcctaa acaacaaatg acattgcaag
    64501 aaatcgatag tatactgaca gaagcctttt tatctcgtaa agcagtaatc attcagctca
    64561 atttaaaaga tgaatttgga agactcttgg atgaggtcga agggcacttc attggtgaag
    64621 cctatgaaga ttactttatg attgaccatc agccgatatt gtgggaagac gtacggtata
    64681 ttgagttaaa ggaaacaaaa aaatggtttg tgacatgaga ggttgtgaca gaagtgatca
    64741 acttcaaaaa ataagaaagg atttttcgaa aattgcttct taaatttttg tggaattttg
    64801 gcttattttt cgaagaagca acttctggaa caacgtatat tagatatcag aggttgtgaa
    64861 aaagtcgctt agttttgagt aacaagccaa ggcgctgatt tcacaacctc tgtctatcta
    64921 tccatctatt cggtaagatt catgcatgac gtcttcttta tttagtatgt agagcccttt
    64981 ttcttctgac cattcaacat aaatcagctg ttttacatct gcatagcctt ctttcttcaa
    65041 gttctccata agccatgctt cagtcaattg attggactga agcactttat gctgaatttg
    65101 cccttcatct acaagcagga tcgataaagc tttgtcttca tctgattttt tcaatacact
    65161 catttgaccg gcattctcta ggataacatg tttggcattt tcaagaaaaa agcattcttg
    65221 ctgtcttaag attgctcgca actgctccat ctcgatatgg ttatttgtca actctgtcat
    65281 gttgatgacg ccgtctttga ttagaacaga tggctcgcct ttgacccaac gattgacctt
    65341 ttcatttttt tggacgatac gttcgatacc ataaatcatt actgcccaaa gcgcaatggc
    65401 aaataggaca tgccctacat ggacattgtc atcataggtt gattcttcta agatcccacc
    65461 taaaacaagc gtatagacta aatcaaacgg tgtgatttct gacatggatt tcttcccaag
    65521 caaacgtacc actaataata aaccgatcaa cccgaacacc agtttcattg taattgaaaa
    65581 aatcattttt tctcccccta actatctgtt aattaaatta tatatgcttt ctcacgaaca
    65641 cgcatggaat atacaaggaa gaaatgtatc cttttactaa aaaaaggact gtgacactgt
    65701 agtgaccccc aaaagttaga cttttttgga gtggagaaat ccactccttt tttttatgct
    65761 ctaaaatgat atttttacac aaccgttacg gttgttttac gaaattggac g
//
LOCUS       DAFEEZ010000008        59470 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000008
VERSION     DAFEEZ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.008"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(284..1594)
                     /locus_tag="LP245_000615"
     CDS             complement(284..1594)
                     /locus_tag="LP245_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBL1518555.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1606..3024)
                     /locus_tag="LP245_000616"
     CDS             complement(1606..3024)
                     /locus_tag="LP245_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1518556.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3264..4832)
                     /locus_tag="LP245_000617"
     CDS             complement(3264..4832)
                     /locus_tag="LP245_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBL1518557.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4836..5246)
                     /locus_tag="LP245_000618"
     CDS             complement(4836..5246)
                     /locus_tag="LP245_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBL1518558.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5243..6166)
                     /locus_tag="LP245_000619"
     CDS             complement(5243..6166)
                     /locus_tag="LP245_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBL1518559.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6163..7041)
                     /locus_tag="LP245_000620"
     CDS             complement(6163..7041)
                     /locus_tag="LP245_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBL1518560.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7028..8365)
                     /locus_tag="LP245_000621"
     CDS             complement(7028..8365)
                     /locus_tag="LP245_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBL1518561.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8368..9471)
                     /locus_tag="LP245_000622"
     CDS             complement(8368..9471)
                     /locus_tag="LP245_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL1518562.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9545..11053)
                     /locus_tag="LP245_000623"
     CDS             complement(9545..11053)
                     /locus_tag="LP245_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL1518563.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11019..11711)
                     /locus_tag="LP245_000624"
     CDS             complement(11019..11711)
                     /locus_tag="LP245_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL1518564.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11733..12707)
                     /locus_tag="LP245_000625"
     CDS             complement(11733..12707)
                     /locus_tag="LP245_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1518565.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13007..13879
                     /locus_tag="LP245_000626"
     CDS             13007..13879
                     /locus_tag="LP245_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1518566.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14337..16535)
                     /locus_tag="LP245_000627"
     CDS             complement(14337..16535)
                     /locus_tag="LP245_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1518567.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16767..17759
                     /locus_tag="LP245_000628"
     CDS             16767..17759
                     /locus_tag="LP245_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1518568.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17819..19240
                     /locus_tag="LP245_000629"
     CDS             17819..19240
                     /locus_tag="LP245_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBL1518569.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19233..20732
                     /locus_tag="LP245_000630"
     CDS             19233..20732
                     /locus_tag="LP245_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBL1518570.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20771..22165
                     /gene="uxaC"
                     /locus_tag="LP245_000631"
     CDS             20771..22165
                     /gene="uxaC"
                     /locus_tag="LP245_000631"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBL1518571.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22324..23007
                     /locus_tag="LP245_000632"
     CDS             22324..23007
                     /locus_tag="LP245_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBL1518572.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23009..23845
                     /locus_tag="LP245_000633"
     CDS             23009..23845
                     /locus_tag="LP245_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL1518573.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23856..25610
                     /locus_tag="LP245_000634"
     CDS             23856..25610
                     /locus_tag="LP245_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518574.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25886..26227)
                     /locus_tag="LP245_000635"
     CDS             complement(25886..26227)
                     /locus_tag="LP245_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL1518575.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26295..28466)
                     /locus_tag="LP245_000636"
     CDS             complement(26295..28466)
                     /locus_tag="LP245_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBL1518576.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28635..29534
                     /locus_tag="LP245_000637"
     CDS             28635..29534
                     /locus_tag="LP245_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL1518577.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29605..30462)
                     /locus_tag="LP245_000638"
     CDS             complement(29605..30462)
                     /locus_tag="LP245_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL1518578.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30447..33149)
                     /locus_tag="LP245_000639"
     CDS             complement(30447..33149)
                     /locus_tag="LP245_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBL1518579.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33162..34451)
                     /locus_tag="LP245_000640"
     CDS             complement(33162..34451)
                     /locus_tag="LP245_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBL1518580.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34601..35647
                     /locus_tag="LP245_000641"
     CDS             34601..35647
                     /locus_tag="LP245_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1518581.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35649..37802
                     /locus_tag="LP245_000642"
     CDS             35649..37802
                     /locus_tag="LP245_000642"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBL1518582.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38275..39726)
                     /locus_tag="LP245_000643"
     CDS             complement(38275..39726)
                     /locus_tag="LP245_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1518583.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39723..41447)
                     /locus_tag="LP245_000644"
     CDS             complement(39723..41447)
                     /locus_tag="LP245_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL1518584.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41440..42054)
                     /locus_tag="LP245_000645"
     CDS             complement(41440..42054)
                     /locus_tag="LP245_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL1518585.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42399..43856)
                     /locus_tag="LP245_000646"
     CDS             complement(42399..43856)
                     /locus_tag="LP245_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1518586.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(43897..44817)
                     /locus_tag="LP245_000647"
     CDS             complement(43897..44817)
                     /locus_tag="LP245_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1518587.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44829..45776)
                     /locus_tag="LP245_000648"
     CDS             complement(44829..45776)
                     /locus_tag="LP245_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1518588.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46255..46974)
                     /locus_tag="LP245_000649"
     CDS             complement(46255..46974)
                     /locus_tag="LP245_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBL1518589.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47023..48669)
                     /locus_tag="LP245_000650"
     CDS             complement(47023..48669)
                     /locus_tag="LP245_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL1518590.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            48848..49438
                     /locus_tag="LP245_000651"
     CDS             48848..49438
                     /locus_tag="LP245_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1518591.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49530..51035
                     /locus_tag="LP245_000652"
     CDS             49530..51035
                     /locus_tag="LP245_000652"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBL1518592.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51119..52471)
                     /gene="celB"
                     /locus_tag="LP245_000653"
     CDS             complement(51119..52471)
                     /gene="celB"
                     /locus_tag="LP245_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBL1518593.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNSSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52471..52989)
                     /locus_tag="LP245_000654"
     CDS             complement(52471..52989)
                     /locus_tag="LP245_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518594.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53005..53331)
                     /locus_tag="LP245_000655"
     CDS             complement(53005..53331)
                     /locus_tag="LP245_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBL1518595.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53344..55323)
                     /locus_tag="LP245_000656"
     CDS             complement(53344..55323)
                     /locus_tag="LP245_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL1518596.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55344..55658)
                     /locus_tag="LP245_000657"
     CDS             complement(55344..55658)
                     /locus_tag="LP245_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBL1518597.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55826..56119
                     /locus_tag="LP245_000658"
     CDS             55826..56119
                     /locus_tag="LP245_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBL1518598.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56197..57309)
                     /locus_tag="LP245_000659"
     CDS             complement(56197..57309)
                     /locus_tag="LP245_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL1518599.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57696..57875
                     /locus_tag="LP245_000660"
     CDS             57696..57875
                     /locus_tag="LP245_000660"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518600.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58069..58239
                     /locus_tag="LP245_000661"
     CDS             58069..58239
                     /locus_tag="LP245_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1518601.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58663..59412)
                     /locus_tag="LP245_000662"
     CDS             complement(58663..59412)
                     /locus_tag="LP245_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL1518602.1"
                     /translation="MVELTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQ
                     SGLTTGADGKLAIDGLAPGVYQLVETQAPTGYELDTTPIEFEIERSQTAVVELTKENR
                     LTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQL
                     VETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPK
                     TGETIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17783 a        12158 c        10398 g        19131 t
ORIGIN      
        1 tttttcgatt tcgtttttcg aaatctttca gcaactcatt tatcataact tatcgtttgt
       61 tatttgtcaa gaactttttt gaagtttttt tcgatagaat caagcttcgc aagtggttct
      121 ttttaacgac ttagttatct tatcacgtct aaaaacatgt gtcaactctt ttttggaatt
      181 ttcataaaat gtttcaatga agcgcgacaa cgttgtttaa tatatcatta aaaaaaataa
      241 aggtcaagct aaaatattat ttaagcttga ccttattata atttcaacga ttgtcaaaag
      301 tattgtttgc agctgtgttg ccagtttcta tagataaatc acagcttttg aaacataagt
      361 tttgtactgc ttcgattcgc ccgaattctt ttgcagttat ttggcaatga gaaaagcaga
      421 catcttctat aggcttttca ggaaatgcta ctaaatcaaa agctcgggaa ggaagtgagt
      481 aacctggaga aaggcatgcc tgtacgtttt tgatgtgtat gtctttgact ttcgtcattt
      541 gctttgattc aggtatttct tcagccactg cttgccaact ttctggcatt tgagcaaggt
      601 cattgctatt ttttctattg tattcattat gccagtccat tatccaagaa aaaggaaatt
      661 gtacatcaat catattcaga ttttctaccc tgatattttc gatcactccc cctctttctt
      721 ttgaagattt cattcgaata ccacagtctg actgaaaaaa atcgatatcg tgaatatata
      781 cgtcactaac tccagcacta acttcgctac caatagttac accgtatcct gaacggattt
      841 tacatctagc aacctcgatt cttgatgatt ttcgattgac tcttgcacca ttgccatctc
      901 tgccagactt aatagcaata caatcatcac cacaggccaa atcacattca tagacacgca
      961 catttgttga agaatcaata tcaatcccat ctgtacttgg tccatcattg ttgcggatga
     1021 ttactttttc tactaataca tcgttagaat aagtgatttg caagttccaa aaacctgatt
     1081 tctgaaaaat caaatcacga acaacaacat gttctgcatg atacagtaaa caagcgcgtg
     1141 gacgtttaat agcataatcc gcaatccaac gaagtccctt ttgatcgtat tcagctcttg
     1201 tcccgctttt ttgatctttt ccccaataca gctcccacca atggtctcct tgaccgtcga
     1261 ttattccttt tccttctata agaatatctt tcgccgagag aacattcaaa atcgctgctg
     1321 gccatttcat ttctacgccg gctactcgtg tatcgatttc tggaaatgct tcgatatctg
     1381 ttctcccctt gaggactgca ccttcttcaa agataagatg actcttatct tttaaaaaaa
     1441 gggctccgac taaataaatg ccttttggaa taaatacagg taagtgttct ttcgcacctt
     1501 gatcgattgc tttttgcagt attattgtat catcttgttg agtgtcgttt gttttaaagt
     1561 tcaaagcatt gataatccct ttttttgtcc gcaatacgtt tctccctatc tttcattgat
     1621 ttttttcaat tcttcaccaa taaatacagt ttttgaacga ttcagtgggt aacctactag
     1681 caaaatgatt gcggatacaa ataagcagaa tgctggtaac aagtttgcca tcgtataaat
     1741 cctttcttgt actaaaactg attggatggc tccacctgtt gtagacgatt ggtaaccaat
     1801 gagtgccagc ataaatccgc ctaccgctcc tgcacatgct tgtcctactt ttctcgcaaa
     1861 agaatttact ccatatactg ttccatcttc tcttaagcct gtcttatatt gatgataatc
     1921 aatcacgtca gtaatgaatg cccagaccat caaattgaat aaaccagatc ctaaagtagc
     1981 gataaataaa agaatcagat atacccatgc atttgttata tgaaggaaat acatcagcaa
     2041 gtacatacat gaagaagcaa gtaacgcaaa tacgcttgct tcctttttac caaataattt
     2101 tgtcagcttt gtagcaaatg gtgctaaaac tactactgtt ccgtaagtaa ataaaagagc
     2161 aacagacatt gcttgtttat tatggaagta atcattgaat aaataagtca tattcgtccc
     2221 agctaaaatc tgattgatca caatgaaaat gtcaacaatg actaaaataa tcagtgctcg
     2281 attagctaac aaacctttta ccaactgaga agcagatact ttttcgtttt tgacaactct
     2341 tactctttca gtagtcaatt tacaagttaa catatatgcg acaaatgcta ttgcagcaca
     2401 tccgattgaa atccaaaaga aatgattccc tgaaacgact tgttgtccac tcttgttatg
     2461 ggtatacatt aaaatcggaa tgaagaatcc tgtagttgat ccgccaatcg cagaaccaat
     2521 gcttcggaac gtggacaacg aggtgcggtc attaggattt gagctaattg ctgctgccat
     2581 tgctccatac gggatattga ttgttgagag aaaaatccca taaacaatgt atgaaacaaa
     2641 aatataagca atcttcaccg tcattggaag atgttggacg aatggcaaaa acaaaatgac
     2701 agtcactaag caaaatggat acttcatttt tctgatccaa ggaataaatc ggccagtttc
     2761 tgttaactct gagacatcac ataatcttcc aaccatcaca tcagcaaacg catccaaaat
     2821 tctcgaaatc aagaataacg tacctacgat tgcccctgaa acgccaagaa cattcgtata
     2881 ataaatcatc aagaaactat tgactaaacc taaaataaaa cagttaccta gatcaccgaa
     2941 catgtagcct atcttatcgg aaatcccaaa ttcctttttt tcttttttta ttgtatttgc
     3001 tgtaacagca ttttgtgaaa gcatttgaat tcctcctacc tcttctagta aacgttttca
     3061 aaattataac tctttttttc ttgtttttat attcacaatg ttggcttttt attgcattat
     3121 cttgacagat aaaaaacaaa aaataatcta aaaacattga tgcataagat tgataacttt
     3181 ttttacataa caatatatac aaacaaaaaa attcactaac tagtgaaaat aagttagtga
     3241 acctcattta ttaaagaatt aaattacaga tgatcttttc catcatactt gaaaaactca
     3301 aaatcagcat aacttcctct ttttttattt agatcatgca ctgctatccc gataaaattt
     3361 ccagtaaacc ctcctgagag tatacacatg tttttttgcg gacctacttt cttccattct
     3421 tcagttgata cgtctttcaa atgaaactgt gctgtctctt tctttacagt gactttcaaa
     3481 aaagtcttct tttctgtgag tggaatcgtc caatcttcta tttgtgctac tccgttttct
     3541 gattctatca tacgtaggca ttttcccttg tcctcattcc aagtaacata acaataaata
     3601 taattggatt catttaagta cagtaccagt ccagccatct gattaaaatt attaggcatg
     3661 tattcaaatg ctgtctccgc atcaaaagta aaatccgttt gccgaatagc taacaaatga
     3721 tgttcgaagg tagattgaag agattcaccg gaaatcagac gtaaaaaacc tggtctacat
     3781 tttgtatcac accaatcagc atttggcaaa atgcgtctgg cattccagtt cttctttagc
     3841 tctccttcaa atgtatccat aaactgatga tctttttctt gttgtacctc ttcatttgtc
     3901 tcaatcatta tttcttccat cggagttgtc tggctatctt taagtcttaa ccaatcgtcg
     3961 gacgtccaat acacttcttg aatagcggtt tctcttccca aaatagccgc accgtttaat
     4021 ggtctggtac aaagatatgt catgtaccat cttcctgacg gggtttgtac taagctccca
     4081 tgtcctgtac attgcaatgt agaagcaggt ttgtcactag ctgtcagcat aggaaaacca
     4141 ggatcaagct cgtaaggacc agtaatattc tttgctcggc aaactgtaac tgaatgtcct
     4201 cttcctgtac cgccttctgc cgtcatcaaa taataatacc cgttacgaaa atacaaatgt
     4261 ggtgcctccg ttttcgctaa ttctgtacct gcaaatattt tatagatggg accatcaagc
     4321 ttcttcttct ctgcatcata ttcttgtaat acgataccgc tggatttatt cggtgtgtcc
     4381 agacgataat cccatagttc attgacaagc catttttttc ccgtttcaag atcatggaac
     4441 aaagaaggat caaagccgtt actatttaaa taaattggtt cggaccaagg acctgtgatc
     4501 tcagatgcag tgatcaaata attgtggaca tctttaaacg gacggcctgc acttttgaca
     4561 tctgtgtaaa caagataaaa caatccatca gcataactga tctgtggcgc ccatatactt
     4621 ccatttgtag gatttccttg caaagatact tgagtggtca aaatatccgt tgtatgtgac
     4681 cagttgacta aatttttcga ctcatatact cggattcctg gaagccattc aaaagaggag
     4741 acaataatgt aataccgctc tttcactctt aatatattag gatctggatt gaatcctctt
     4801 aaaataggat ttttcacttt gatagtctgc atgattcagg ctccttttct cattcttact
     4861 cgatataaac tgaatgcccc agctgcgaaa taaaaaaatg caaaaggaaa cgcaataaac
     4921 tgagtgccaa tcaacaatat gaatcctgtt ataaaataca aaccagtggc agttgttaag
     4981 tattttcctt tagcagtcaa aaacaatgct actgctaaaa aagcaagtga aataaacaac
     5041 acaacggcaa acagaccagt catgtcctgt aataatccaa atgtattttc taaagacaaa
     5101 gttgaatgat ctacagcaag cgactgataa ctttttttaa actctgacgc agacatatta
     5161 cttaaagtaa ctgctaaccc gccaaagaaa atcaaagata gactgccacc gaccattcct
     5221 agcaatagtt cccattttct tttcatttct gaaccccctg cttttctaaa tgtatccatt
     5281 caggtctttt gatcgatgtt tcataattgt tattacgttc agagaatttg acagtctgtt
     5341 catttttctt gtcatcccaa ttatcccaac cagttgggtg aacatgccca cctatcttac
     5401 acgcttcaaa taagacattt gcatacggac gccacggtct tcctaaatag acgtttctag
     5461 tatcaggttc tgcagtcaag gtacagcttt caaaacgata ccctgttttt tgatttttcg
     5521 gcgtagatgc tgctgtgatg tatccaggat ttttactggc taagctatgg atatgacact
     5581 gatgaaaaac ggcatctgcc ccaccaaata tgaaatccac cgttccttca atccagcaat
     5641 attcataggt ctgacgacaa tactcaggat tggcagaagc cggtgtacaa aaaggagtac
     5701 catctttttg caaatcaggc aacggacccg tgcataaggt atcctgataa ccagatagtc
     5761 gacagttttt taaagatacg cgatctcctg aattgaataa agcaacagcc tgtcctacct
     5821 tttctcctgg acctgctgta ttttcgatgt gaagattttc taatacgaca ttcgatcctt
     5881 ctaagaaaaa agtagcactt cggaaagtcc ctaactggct accgtcaaga tactcctgtt
     5941 ttgcaaaacg attaccggag ataactactg ttcctgctcc cacaagttta aaattggata
     6001 atctgctttc tatatattca tcatatcttc cttcttttac tatcaagacc tttggatggc
     6061 tatccggcag gcctgccaaa taatcgattc cttcttggat agtttcaaaa tccgtcgggg
     6121 tatctatagc attctttcca attatcagtt tgtctttcat cctcataaat gctcccttat
     6181 gaattgtttc caaatatttc tcatttcttg tgtttccata tgaccgcctg ttaaagaaaa
     6241 agaagaaaag ttttctggac tacccattga ttgatacttt ttgtccagcc cttttctcag
     6301 cttcagtacg ccttcgtcca agcacatcgt atcgtttttt ccaactaagc taagacgagg
     6361 gcgcggagcg attttttctt ggattgctaa cgttgtataa gctgtcaata gatttggcac
     6421 atagtaataa aacccatgat gatctaggcg gcgatgtagc aaaagtattt cgatgtccac
     6481 ctgtgccgct agatcaatac aaactttgac acgagaatcc aatgctgtca cccaccagct
     6541 taataagcct cccatagaaa gaccaatcgt tgcgagccgt tgagtatctg tgtcttccct
     6601 tgtctccaaa taatcgatca agctgatcac atcataaata cgcattcccc ataacgtttt
     6661 tcctgttaat aaaaattgtt tgaacaactc gctttcagaa atacctccgc gttcttcaaa
     6721 tccccaagca tcaatcgacc aaacagcata tcccattcct gtcagtactt ctgcaaaaga
     6781 tggagaagct aagtaaggag caccatggat caattcactt ttcccgactg aaaaatctcc
     6841 gccgtgagaa tgcaggtaaa ggaccggcgg aaacggtcct tctttttctg gataagcata
     6901 gagggctggt actgtttcca attcatttaa gtacaattga tagtattcaa gcataaaacc
     6961 gttttgtttt tctcggtata atcgttttcc actaggggta tgtctgctag atggagcacc
     7021 taaaaaatca ttcaactgca taagcaaagt ttttacgaac aaccagttca tccatatttt
     7081 ctgattgatt tgattggaat ttctcaatac tgatttcttt agtattttct aatagaaatg
     7141 ctggtccctc gtgattttca atcgacatct ggttaaagga aaccttaccc gcaaagccaa
     7201 tataaaatcc ttgtctgctc atttcctcta ttcctgtcat catagcagga acaccgggaa
     7261 ctgcatcttg ggccatcgag acatcgatat tgtcaaatgt gatttcttgt atgaattgtt
     7321 ccgctaatcc ataaataaaa cctgcagaag catggacatt ccttgccgtg atattcgaaa
     7381 aatggatcct tctgaatgct ggtgtccgtt catctatcgg ataagccttt ttttcccata
     7441 catacggttc tttccctcgc ggaccacaga aataataaag attcagtata aatggacaca
     7501 tcacattatc catgactata ttggatactc gaatatcttc aacgatcccg cctcgacctc
     7561 gtctagattt caatcgtatt cctcgatcag tttcttggaa gatacaattt gaaatggtaa
     7621 tattacgaat actaccactc atttcacttc ctaatacgac accgccatgt ccatggacca
     7681 tcgtgcaatt tgtgatcgtg atattttcgc aagcgatcct ttcgtacgta tcttcagtcc
     7741 ctgccttgat tgcaatacag tcatctccca cgtcaatatg gcaattacta atacgcacat
     7801 ttttgcatga ttctggatca attccgtctg tatttggtga atccgctggg ttcaagatcg
     7861 tcaagttatc aaacgttgca ttactgcaaa gaatcgggtt gatcgtccaa cttggtgact
     7921 ggatcaattt aatatctttc acagtaattc gatgacagtt atggaaactc atcaatttag
     7981 gacgaggata agcgagatta tctggttcat ttctaaaagt atgccaccat ttttttccat
     8041 ttccatctaa tgtaccgaaa ccagtgacag agatgttctc tacattttga gcatagatac
     8101 aggaagcata aacttttcga tggactcctt cccaacgtga atgaacaaca ggataatctt
     8161 ttggatcgtc agagaatttc agaaccgctc ctgcgcttaa atgaagttcg acattgcttt
     8221 ttaaaaataa agctcctgtt agaaattcac ctgctggaac aactacggtc ccgcctccgt
     8281 cacttgctgc agcatcaatg gcttgttgta ttgcttcagt attcaattca tcaattgatg
     8341 cgccaaatgt caaaatatca tacatattta taatgcctcc acttcaatca atgcttgcaa
     8401 gaatgcacca acgccttttt gatcattaca aataattggt tcactgatgt agtaagcata
     8461 tgaaccatct cgctgatctg ctccgcctaa ccctgctact tgacagtttt tattcaagtt
     8521 cagccagcct tcttttgttt ccagaacaaa ttcatcaagt aatccttgat gtgatttctt
     8581 cacttgtgga agccattctt ctttgttcag cagtcccaaa cgtattcctt tagccattgc
     8641 gtaaacaaac atactactgc cggaagcttc cagataattt cctttccgtt ttgtttctgt
     8701 tgttacttga taccatgtcc cgctgttttc ttcttgatat ggaagtaatg cagccagtgt
     8761 cttttctaga atttctttca gcaaagaaca atctgtttct tcatgaagta attcataggt
     8821 atctgctgca gccatcaaat accagccaat cgatcggctc caaaaatgat gggatagacc
     8881 tgtttttgga tcagcccatg gttggacctt cttttcatcc catgcatgaa tcagcaaatt
     8941 tgtttttgga tcgaatagat gtttataact gatttcaaac tgtctcaaaa catcttggta
     9001 atctttttct tcactaaaat tctggataaa ttcagcataa aaaggagaac ccatatataa
     9061 gccatccaac caaatttgat aaggataaat ttctttatgc caaaaagctc cttcggatgt
     9121 gcgtggatgg tttgccaact gctgggaaag gagttctgct gcttttttat atttttcttc
     9181 gcctgtttct ttgtacaata aaaagaaaag ctttcctgta tttacatggt cgatattgta
     9241 ttcttcaacg ctgtagccac ggatcgttcc atcttcttgc acgaaatagt cgatattgtc
     9301 ttttatgaaa tcaaaataaa ttttttcttg ggttcgttcc caaagtaatt ggaacccttt
     9361 aagtacgacg ccatagtcat aagaccattt tcctttatac cacttttctt catataagcg
     9421 aggtgttctt tccatgatac tttttgctaa tttctttgac cagttttcca ttatttgctc
     9481 tcctttaaaa attaaaatag gatttgggac aaataccaag aagtatttgt cccaatcgtc
     9541 tatattactg tgccgctgct ttgtatgctt cctcgtactc ttgtgtgatt cgatcgcctc
     9601 cttgtgcttt ccagtcttct acagcttttt tgaatccatc ttcgtcaagc tgtcccatga
     9661 tgtattgcac cgtagcatca atgacgattt tttcaatttc tgatcctact tcattgttcg
     9721 tcggtgaatc caatggcaca gaaggatcca ttacagcaaa ttcttcattt tctttgatca
     9781 attgattaga gaattctttt tcagggtctg tatctttgaa agagaacgtc acttcactag
     9841 gacgagagct tgataacggt tgcacctctt gttgccaaag atccatatcg ataaattcga
     9901 tagaaccatc atcattcaat tcataatgcg ttccttcgat accgccagtc atcaatttat
     9961 acacatcttc ttctaaaaga tcatcaacaa attgaagtaa tttcttcaat tgtgcttcgt
    10021 cttttacttg agatttggga aatgctagca agccgccaat accatttcct tctgaccaaa
    10081 catgataacc gccgccttca ccatctgaga tcttgtttac aggcactaat tccatatcat
    10141 cttgaatacc ttgacccatc gtcttcagat tcttgatatc caccattcca gtgtagattc
    10201 cagttcttcc ttgtgcaaat tgttcttgct gatcagtctt ttgggtaact gcaaagtctt
    10261 gtgccaaata gccattctca aatagatctc ttgaaaaatt caaagctttc atatactctt
    10321 ctgtatcaaa ttctggagtg aatttgccat tatcgtctac agcccagcca tttggtgctc
    10381 caaaataaga agtgaaaagt ttaaagctgg tataacgaat atcactaggc gcacgatcgc
    10441 caaaaccaac tgtgtcgtcc acaccatttc catcaggatc gttttctgta aattgtttag
    10501 ctacttcata aagctcatcc atggtagttg gaacatctag tcctagatta tccaaccagt
    10561 cttttcgaat gactaagcca gcacgagcgt agtctttttg tatcggtacg ccgtacaagg
    10621 caccgtcgat actcgcagct tcgattctat cttcagaaat ttgacttaaa tttttatagt
    10681 cttttaaata ttctgataca tcccagaata cgcctgattt taacgcattg cggacagaag
    10741 agtttttcaa catcgcaatt tgaagtgtaa cgatatctcc tagttcatca gaagccaatg
    10801 cagttgttaa tctttcttct tttgaagcat caggaatcca gttgaatgtc agttccgtat
    10861 cggttttttc ttcgatcaag ttcacaatcg tgtctgtagg cggtgaagca tgatgcaaaa
    10921 tatttaacca agtgatttta gcttttccat cttctgtctc tgaagaactg ttacttgaac
    10981 tgctgccgca tgcggcaagt gctagaattc ctgcaaaact aagacctaat tttacgagcg
    11041 ttgctttttt cataaatttt ctccttcact gttttaataa tatttttgtt ttcttctgtt
    11101 ttttctgtat atgagttctt ccattccaaa tggcaaaata tagaatttgc tgtccacgtg
    11161 actgcggaaa agaagagact gccaccgata aaggttaaaa cacctggcat tgtttggatg
    11221 atcatcagat aaatccctac catacttaat atcaacacta atgagtaatg aagatgtgag
    11281 aatccgaata aaaatgccat tttcattttg aaaaaatatc ctttccaatc ataatgagcc
    11341 atgattggga aaatatagag tgctgagagc acatatatga acgcagcaat atacaaagcg
    11401 atcctaagat accaattgtg tatgaaagaa agatccacaa gtaaaacaat cccgatggcg
    11461 ccatatatcc agctcatcag caaggtttca cgatagtttt ctttaaaata tgtgaagtac
    11521 gttttcgtca aaggaaacgt ttcttttgag cgcagccatt ttctaatcac tgcaaccatc
    11581 gcatacgatg caggaccgaa agtaaaaact cccaaacctg cgatgactaa accgccccac
    11641 agaaaattca aataaaccaa ctgtaaaata cgatttagcc ttccgtttat tttatctaat
    11701 gactgcagca tatctttccc tctctttcta tcttagtaaa cgccgtcttc tcctagcttt
    11761 ttggcaatct tattagctaa aattaccata aacaatccta cgaccccttt aaacaatccc
    11821 attgctgtac tgaaacttaa ctgtccattc ttcaatccag ctgtataaat ataggtgtcg
    11881 aaaatttctg caacgcttcg attcaatgaa ttcaataaca agtacatatg ctcgaaccct
    11941 aagtctaatg tctgaccgat ttttagaatc agcaaggtaa tgattactgg acgaattgcc
    12001 ggcaatgtaa catgccatgt tttgcgtaag cgtcctgctc catccatttc tgcagcttca
    12061 tacaactgtg tatcgactgc agttatcgct gaaaggtaga tgatcgtaga ccagcccaac
    12121 tctttccaga tcacttgtcc gatatatact gtgcgtgtcc attcagggga tgttagaaaa
    12181 ctgatttttt caaatcccat tgttgcaagg aattcattca atacccctcc gtcaacattc
    12241 aaaaatacat aagtaatcga aacaatgatt acccaagaca tgaagtgagg gatgtaaatg
    12301 atcgtttgaa tcccgttttt caatcgtttg ttcgttactt catttaatag taaagacaaa
    12361 atgattggca tcggaaaaaa cacgaagata tttaatccga acaagatcaa cgtatttctt
    12421 aataatgtaa agaatgtcgg ttctgtaaac aaacgaatga aatgtttgaa accgacccaa
    12481 ggacttccca ttattcctaa aaatggttga taatcttgaa aagcaataac gagtcccccc
    12541 ataggaagat acctaaaaat caagaaataa aggactcccg gcagaatcat cacatataaa
    12601 aatttattcg ttttgattcc tgcaattatt ttttttcgtc ttctgagctt ttcttctttt
    12661 ttcgatagcg tcagttgaaa tggttcttgt ttctttacac tttccataag cccctcctta
    12721 gttttgtgaa tgtttgctgc ttatgacttc atgatagata actatctgaa ttacgtatat
    12781 aatcattttt accgtaagta aaaacgctta catagcaatg atttttgtgc tatacaaaac
    12841 gataaagtgt attttttcac aaataaacta cgcatagcaa accttctatt tttttctatc
    12901 tgacacttag cataggaaat gattatatac gtaatctttc accgatgata aattgaacat
    12961 atagaaacag aaacatttaa tttattttga ggaggagcct atctatatga aaaagaaagt
    13021 ctctatagga gaaagaagtt ttacactttt caacaatacg tttctaattt tgctagcttt
    13081 gatctgtatc gttccttttt taaatatcat cgctacatct tttgcttcta cacaagaagt
    13141 cgtcgcgaaa aagtttatcc tttttcctac taccttttct ttagacgcgt atcgctacat
    13201 tctttctacg ccgaccattt ttagagcact tgctgtttcg attggtgtta caggtgtcgg
    13261 aacgatcgtc agtatgtgtg caacttcact gatggcctac ggtctttcca gaaagtattt
    13321 gtttggtcga ggtttcgtca actttcttgt tgtattttct atgttgttca gcggggggat
    13381 gattccaacg ttcttagttg ttcgttctct agggctggtc aattcttact gggccatgat
    13441 cctgcctgtg gctgttaatg caatgaatat gatcattatg agaaactttt tccaagcctt
    13501 gccggatagt ttggaagaat cagcaaaaat ggatggttgc acagattttg gtgtattttt
    13561 caaaattatg ctgccattag cgttaccgtc tattgctact atctcgcttt tttatgctgt
    13621 tacttactgg aacacttata tgactgctat tttgtatatc aacgattcat ctaaatggcc
    13681 gatacagatt cttttacgcc aaatcgtcat tgtatcaagt gggatgcaag cagaaagtag
    13741 tgccgttgat gtgattccac cagcacaaac agttaaaatg gctgttatcg ttattgcaac
    13801 agtgcctatg ctgattgttt atccttttgt tcagaaatat tttgtcaaag gagcactcgt
    13861 aggttctgtc aaagggtgat tatgtactga acgcaaaatg gtagttgtgt cagaagtggt
    13921 cagcttcaag aaataagaag gcatttacga aaattgcttc ttaaattttt gtgaaatttc
    13981 ggcttatttt tcgaagaatc tactcctgga acaccgtgta tcagaggttg tgaaagagac
    14041 gttcagcctt gagcgatgat aaaaactctc acaaacattg cgacgagtaa cccacaggag
    14101 caataagaag cgattttgaa aaatagcttc ccatatttca caaaattatg ccttattgtc
    14161 gatagcctgt ctcttgaacg ccatttattc gtaaaaaaga actgtgacaa gacttttgtc
    14221 acagttcttt ttgcgtgctt agccttgaaa tttaactatc cataaataca aatactaggg
    14281 ttattctaac ttcttttatt gcttgaatca gtccacaaga aaaacagcct cttgattcac
    14341 aaatattttt ttcgatattc tcccggcgta atcgattcct tctttttaaa gaaacgaata
    14401 aaattttgcg gatttcgata ttgcaatctt tctgcaatct cttttacgga gaggttagtc
    14461 tctttcaacc atttttttgc tacctctaaa cgatgatttt gaacaaaatc accaaatttt
    14521 tctcctgttt cctttttaaa tacattactt aaatagttag ggttataatg caacctatca
    14581 gcgatcacat ctaaagacag atcacgatca tattctgtgt agacgatatg cataatattc
    14641 tccgacaaat ttttaaattc atgatcagtg attgcttgag agcattctgt gattggcaga
    14701 actaattgtt ctaaaacaag tttttctagt tctttgggat gataattgtt cagtgctttt
    14761 acataaattt gtttcatgtt atcaaagttt tttgaatcta ctcccaataa ctgtcctaat
    14821 tgaacgagtt cattgatcaa gcggaccgaa actacttccc gactcaaagg atttttattt
    14881 tgtgcaaaca atgcatcaat caattcatgt actaaattct tcacttcctg atttccagaa
    14941 cgaatggctt caaacaatcg attttgttct tctatcggat atctaataag tgttttttca
    15001 tgagcagcag gaacgatttc ctgataaaaa ataattgaac ttggaccagt atttacacga
    15061 taatacaggg cttcttttgc ccgatcaacc gattgcttgc tttcattcag cgtttcgaac
    15121 cggttactga tgcctatact gatagttaaa ttcaagtatt cttttacacg tttttgaatg
    15181 agtcggcaat actccatgac ttttttgctt gcttctgcat catctttatc cattcgataa
    15241 atagtggctt gcatttcttc attcaaaacg atcggcagca ttcgattttc ctttggcaca
    15301 atttccgtga tcatgttgtt gatcgctaaa agtagcaaat cacgctcccc accgtgacta
    15361 tcttctaaca gatcgatttg aaccaaagct gtataatagc agtcattttg agaactataa
    15421 ccaaattgct gcaaccgctg atctagttct cgcctttcta ctcgatttct aaataaacta
    15481 agtacaaata gcgtttccag ctgtggcttt tgggtaacta agtgtgcact taacgcttct
    15541 ttttctccta tgatccgact gactgattga gcgaccaaat ctagttcttt cccactgaat
    15601 ccttttgatt taagattcag acgttcctgt atttgagaaa tcggacgggc aaatctgtcc
    15661 gaaaataagt aggaaagaag accaatgagt cctaccagtg ttaaagacac tgcaactagc
    15721 ccgattctca gattgcggat cattgcgcca attgcactag agtcaacttc taatctgtaa
    15781 atccaattat tataatctga tttcagtact atatacgttt tatctttttc tcttatcact
    15841 ttcagctgat tgtaatctag atccacgtcc gttaatacag ttggttgctc tttatttttt
    15901 actgtctgag tagtaaaaag gttgccaact tcgttttcaa tagaaagtat gtcttctcca
    15961 ctttcaccaa caacttgttc tattgtatgt ttctctatcg tagcaattcc caatgcatat
    16021 ttttcttttt caaacattgg caaagaaatc accatttcga ttcctttgtt tttcttttgc
    16081 caaaataaat tatttttgtt atttatgtac ttctgttgat acttttcaat ttcctcttcg
    16141 gtcagttgac tcaacgatcc attgattact ccccatttac cagccaaact gactaaatca
    16201 taattattat catccataac aatcgtttct ataaaattta gttctttcct gatttcagaa
    16261 taagtggagt aatctgtata tgtcagcgga tgcttgaata tgtccgagaa atttttggtc
    16321 gaaccatacg tagaaaacga atattcaatc gttctaattt tccattcaac gttagtttta
    16381 acttgcctga gcaaattctt tttgtctgtt aaataactcg attcgatcga ttcataggta
    16441 ttctggtaaa tgaataaact aaatcctatg acaagtacgg ctcctaataa aaacatcggt
    16501 aaaaatattt tataaaatac tgtacttttc ttcattttct tcctctcctc cttttaaaat
    16561 aaaaggcttt catttttctg taaaattgat actcatctaa ttaaatgagc attccccgct
    16621 ttcaagaata gcataattaa aaataaaaat ccaagtaatt tttaacgtgt gcaatctttt
    16681 catatcaaag atctattgac ttatcgtagt tatcgtaata tgatgaatgc gttaacaaaa
    16741 agtgaaaaag taaggaaaat gatggaatgg taacgatcaa agatgtcgct aaagcagctg
    16801 gcgtttctca tacgacagtt tctcgtgctt tgaataacag cagtttaata aaaaatgaaa
    16861 caaaacaaaa aatacgacaa ctagctaagg aaatgaatta ttcgccaaac tatagtgcaa
    16921 aaggtttagt gaatcaaaaa aaatatctaa tcggactatt tttctcaagt ttgcataaag
    16981 gaacttcatc aaatttccta gcagattcca ttgcaggcat ccattcagta ttagacacaa
    17041 attacagttt atctgttgaa agtatcgatg ttgttgattt aacagaaatc aacctgcaac
    17101 gctacgatgg actgatcgtt atgagtcaaa gtgatgatga tcagcctttc atcgactatc
    17161 tcaaagaaaa agaatttcct ttcgttgttg tcaatcgtca catcaatgat ccagcggtta
    17221 tcaacgtcac tgccgatgat gcggccggtg ttatgcaggc agtagattac ggtattggat
    17281 gcggacatac gaagatcgct tatattggcg gaaagaaaaa ttttcgttcg acaaaagaac
    17341 gggaaaaagg ggtattgaaa agtctaaaaa aagcgagcat ccctgtcaat ccagcctatt
    17401 ttttaacagg agattacagc ttagaaagcg gcctccaaaa catggaatac ctattatcac
    17461 tttctgacct gcctactctg gttttttgcg gcaacgacga catagcgatt ggtgcattga
    17521 gagctgtaca tttagctggc ctccgtgttc cccagaacat ttctctgatc gggttcgatg
    17581 attctccagt cgtctcctat ctcaatccgc cgcttaccac cgtacgtaag cctttgaaag
    17641 aaatgtgtca agaaggaaca aagcttttac tagatttgat cgaaggcagg acgatcgaac
    17701 aatctaaaat tgagctctcc accttgttga tccttcgtga gtcgatcaat tacttgtaaa
    17761 ctacaagtaa ttttatataa aaatgttaac gtgtgcataa cacagaaagg aagtttatat
    17821 gaaaaaactg acaaaagaat tagtgaaaaa aaacgaagca cctgtaaaag ttcttcagtt
    17881 tggtgaaggc aattttatgc gtggatttat tgattggcag attcagcagc tgaataacca
    17941 acaattgttt aaaggtaatg ttgcaatcat tcaaccttta gaacaaggtc ttggaaatat
    18001 gatgaaccag caagataatt tatatacggt cattttacaa ggactcagca atggcgaaat
    18061 cgttgatact tccgagatta tcaccgtagt agaacaaatg atcaatcctt atgatgaatg
    18121 ggatgcttat ctatctctag cagaaaatga cgacttggcc tatatcgtct ccaatacaac
    18181 agaggcagga atccaattcg tggagactga taatttaaca gatactcccc cacagagcct
    18241 cccgggcaaa ctgacagcct ttttataccg acgtttcaaa ttaaacaaag ctggctttac
    18301 catcattcct tgcgaactga ttgacagaaa cggcgaacgt ctaaaagaaa tcattttacg
    18361 ctacgcagaa aaatgggatt tagaacctgc ttttgttgag tggttagaaa aagaaaatgt
    18421 tttctgttgt agtttagttg atcgcatcgt cccaggttat cctcgcgaag atgcaggtgt
    18481 tttcaatcaa cggcataact atgaagatca attgatggtc aaagcagaac cattcatgct
    18541 ttgggtgatc gaagggccta aagaattgga gaatcaacta ccattcaaac aggctggctt
    18601 gaatgtcatc atcacagatg atatgactcc ttatcgtgaa cgtaaggtgc atttgcttaa
    18661 tggaccgcat acagcgatgg tccctcttgc tttgttggcg gaattggaaa ctgtagaaga
    18721 agtaatgaaa gatcctttat tctccgcata tgttgatcag ttattcaatc tagaattgat
    18781 tcctatgctt tctttaccta aagatgaatt agccatttat gctgaccaaa tcaaagaacg
    18841 tttcttgaat ccttttgccc atcacaaatt agaagcgatt tcattaaata gtgtttcaaa
    18901 gttcagcacc cgtctgcttc cagtgttcaa gaagtatatc gaagaacaaa atcaggtacc
    18961 accgttaatc actgtttcac tagctgcgct acttcttatg tatcgaggcg atcaagtaaa
    19021 gccacatgat gatgaaaaga cgataagcga atttactgat gcttggtctg ataatggaac
    19081 agctattcct cgattattgc aaaacgctgc gctttgggga gaagatttgt ctcaaatacc
    19141 gaatgtgaca gatacagttc aagaaatagc tgcaaagatc gatcaaaaag gtgtccggtc
    19201 agtattacaa gaaatgaaag gaacgatggt ccatgcttga aaccctgcaa ccaacaatga
    19261 aattaaatcg acgagacagt gtggtcgtcg cattaacccc tattccaaaa caaacacaac
    19321 tgacgattga tcagcaaacg atcaccactc ttgaagatat cccgcaaggt cataagattg
    19381 cattgggtga tttgaaagct ggagacaacg tgatcaaata tggctatcca atcggtcatg
    19441 tgacgacaga cgtaactgcc ggtcaatggc tgcacactca taatgtaaaa accaatcttt
    19501 ctggtgaatt ggattatcga tatgaaaaag atgtccatcc aagtcattac ctttttgaga
    19561 accgaacatt tcaaggttac ttgcgaaaaa atggaaaagt agggattcgt aatgatttgt
    19621 ttttagtacc taccgttggg tgtgtgaatg gcattgctga actgatcgtc aaacagttca
    19681 aggaaaaaca tccagatctg ggacagtttg accatattac gattttaaag catccttatg
    19741 gctgttcgca gcttggaaaa gatcatcaaa atactcgaga aattttagcg gacgcagtaa
    19801 atcatcccaa tgccggagga gttttagtat ttggattagg ttgtgagaac aatacagttc
    19861 ctgaattcaa aaaaatttta ggtgaatatg atgaagaacg agtgaaattt ctagtggctc
    19921 aagatgttta cgatgagatc gaacaaggtg tggctctatt agaagagctt ttaacagcgg
    19981 cggaaaatga ccagcgcata tcagtcccgc tctctaagtt gaatgtcggt ttgaaatgcg
    20041 gcggttctga tggtctatcg ggaataactg ctaatccttt acttggtgca ttttctgact
    20101 acttgattgc tcaaggaggc agcacgatct taacagaagt gccagaaatg tttggcgcag
    20161 aacaagtatt gatggcacga gcggaaaatg aagaagtttt tgactcaatc gttgacttga
    20221 tcaatgactt caaacagtat ttcttgtctt acggggaacc agtttacgaa aacccatctc
    20281 ctggtaataa agcaggtggg atcactacat tagaagataa gtctttaggc tgcacgcaaa
    20341 aatcaggaag ctctcctgtc gttgatgtgc tacaatatgg cgaaaaaatc agaaaaccag
    20401 ggcttagttt attgcaagct cccgggaatg atcttgtagc tgcctctgct cttgcttcat
    20461 ccgattgcca gttggtcttg tttaccacag gaagagggac tccgtttggc tcatatgtcc
    20521 caacggtcaa ggtatctacg aatacaactc tttttgaacg caaaggtcat tggatggatt
    20581 ttaatgcagg cgtcttatta gaacaaccaa tggaagtaat cttagaatcg tttgttcaaa
    20641 aaatcatcgc tgtagctagt ggagaagaaa cgaaaaatga acaaaatgac gttcgagaaa
    20701 ttgccatttt taaaaacgga gtaacacttt gattttcata aaacagtata aaaagaaaga
    20761 aggaagattt atgtttttat ctgatgattt tttattaaaa gacgattggg cgaaaaagct
    20821 ttaccattcc tacgcaaaaa acatgcccat tattgattat cactgtcact tagatccaaa
    20881 agaaatttac gaaaacaaca atttcagcaa tctgacagaa gcttggttag gaggcgatca
    20941 ttacaaatgg cgcttgatgc gagcttgcgg cgtgcctgaa gaaaaaatca caggaaatgc
    21001 ttctgatttt gaaaaatttt tagcttggtg tcaaaccgta ccaaaaatta tcggaaatcc
    21061 gctttacagt tggtcacatc ttgaattgaa gcgtttcttc ggtattgact tgttgataaa
    21121 tgaagaaaat gcagagaaaa tttggacaca agcaaatgaa attttggcag ctcctgattt
    21181 tcgccgtcgg gaaatcgcaa aaaaatcgaa tgtagaagtg atttgtacaa cagatgatcc
    21241 cgcagacgac ttgcactatc atcagttgct tgctcatgaa gaaccagatt tgaaggttct
    21301 accttcattc cgtccagata aagcactcaa tattgaaaaa gaaggattta atgcatgggt
    21361 cacactactg gaagaagcag ctgaccaaac gatcaccacc tatcaagaac tgatagaagt
    21421 cttagggcag cggatagaat acttccatca acatggatgt cgtgtttccg accacgcttt
    21481 agacatctta cgctataaag aagcggatga aacagtatta gaagagattt ttcaaaaagc
    21541 acgagctaac aaactattat cttcagatga aatcgatgct tatcgtacag aaacactgat
    21601 acatttgacc cacttctatc attctcataa ttggacgatg cagctgcaca tccatgctta
    21661 tcgtaactgt aatacacaaa tgttggaaaa attagggccc gataccggct atgatggaat
    21721 gaatgatctt tctttgacta ttcctctgca aaaattattg aaccgtgcag aagaaacgga
    21781 tcagttgcca aagacgatcc tttattcatt gaatccgaat gactatcctg cgattttagc
    21841 tttgatgggc tgtttccaaa aagaacagaa tggaaaactg cagttaggtt ctggatggtg
    21901 gtacaacgat actcgagctg gtatgcgcga tcaattgaca caatttgctg atggtagtgc
    21961 tttggggaat tttgtcggca tgctgacaga ttcaagaagt ttcctgtcct acactagaca
    22021 tgaatatttc cgtcgtgttc tttgtgaatt tttaggcgaa atggtcatgc gaggagaagc
    22081 acctgaagat gaacaacttt taggaagtct agttcaagcg attagttata caaatgctaa
    22141 aaattacttt ggcttttttg cctaattgat taatagtaac agtaacgaat caaaaacagg
    22201 atagtgaaat aacggaatcc gtttatccac gttttagaga agaagacgga ccaaatttgc
    22261 tccgtcttct tctcttgctg ttctgcttca ttgcctataa acctttatga aagaagagat
    22321 aacatgccta ctatccatat tgccggtgat tctactgcgg cagaaaaaga tgaaaacaag
    22381 cgtcccgaga caggttgggg agaaaaaatc tctgcttatt tttcacccga gatccagatc
    22441 aataaccaag caaagaatgg acgcagcacc aaatcattta tccaggaagg aaggttagcc
    22501 cgtctagctt cacagtttca gccgaatgat ttcttatttg tacaatttgg acataacgac
    22561 cagaaaatcc aagaagaaag aggtacgctt cccttcggta gctatttaaa aaatctgcag
    22621 atattttttg aatgcgcaaa aaaagcgaac gtccaaatgg tcttactgac atctgtgacg
    22681 cgacgagatt acttagaaaa cggaacattg aatccagata tacttggaga ctatccaaaa
    22741 gcgatgcgtg catttgctga gaaacaccat attcctcttt tagatgtgtt ctcaagatca
    22801 caagaattgt tccagacctt ctcaaaagaa gagacaaaaa aattctacct gcatcttata
    22861 cctgatactt gtaaaaatta cccagaagga ctaaaagaca atacccactt tagtccagaa
    22921 ggcgctgata aagttgcccg aataattgtt gaattgataa aagaatcccg tctgcctctt
    22981 gctaattatt tacaaaaagg agtttgagat gtttccatta aatttaggca tccgtgccca
    23041 cgatttagat gttcgaaatc gtgaagaaat cgttcaaaaa gtatcacagc ttcacttgtc
    23101 ccatatccaa tttgcaccac aaaaagcatt tcctgaacaa cttaaattaa ctgacatgac
    23161 acttgggagt gctgcctatt ttggtgaata cttccaaaaa aacaatatcg aactttccat
    23221 tttaggatgc tatatcaacc tatccagcaa aaatcaagaa gttcgtgcac aagcattggc
    23281 aactttcaaa cagcaaattg ctctgtgctc tgcctatcaa gccaagatga ttgctacgga
    23341 aaccggtagt gtctctgtcg gttacacaaa agaaaatttt actgaagaag cttatcagat
    23401 cgccagaaat tctatcattg aattagtcgc tcatgcagaa aattttggcg taactgttgc
    23461 tgttgaagca gggatcaatc atccaatcta taactatcag ttagctaaac gtttaatcga
    23521 tgaagtagct tcaccaaatt taaaaatcat tttagattgt gcgaatttga tgcataaaga
    23581 aaatcatgct gatcaggaaa aagtgatccg aggtgccttg gacaatttac atggttatat
    23641 tacagcgctt catctcaaag actatatcat ggaaaatgga aagatccgca tggtacctgt
    23701 tggcaagggc tgtttagatt tccgcccggt actgcattat atcaaatatg agcgtcctct
    23761 aatgtacgcc actcttgaag ctactcctga gatttatgtt cctgaagcaa tagaacactt
    23821 gcagtttatt taccaagatt gttaaggaga agattatgga ggaacgaata cagaaaagtt
    23881 atcaaaaata tcatgcaaat gcttttcaga cattgctgca tctttatcag ggaaattatt
    23941 ggcgttttgc catgtcagga ctctttttta ttatcaaaca tcttccatct tggttaatgc
    24001 cgatcgctat tgccaatgta atcaatgcag cttcatcgaa agattcttct cagttgcagg
    24061 ccatttattt caacgctttt ttgatggctt gtctgattgg tcaaaatata ttgacgaatt
    24121 attttcatgt aaaataccat agcacttcga tccgtcaagt agaagctgga ctaagagcga
    24181 cccttatcaa gaaaatccaa gaactatcta ttccttatca aaaagaattg caatctggac
    24241 gaatccagtc aaagatcatc cgtgatgtag aagctatcca aacgttgtcc tctcaagtat
    24301 ttgtcagcgg attaaatatc gctgtcaatt tattcgtagc tttaggtatc acgctttata
    24361 aaagtcctgt tgttttcatg tttttcttat tgactgttcc tctcgccgca ttcgttactc
    24421 tctttttccg taaaaggatc agacagtcca actcagactt caggcaagaa atggaagaga
    24481 cttctgcaaa agtgatcgaa gtgatcgaat tagcaccgat tgctcgagct catgggttag
    24541 aaaaacacga aacaactcgc ttaaataagc attttactca aatctatgaa aaaggattcc
    24601 acttagatat cctgcaatct gttttcggat cagtcagctg ggctagtttt cagatatttc
    24661 agctgatttg tttgattttc actgggatat tagctttaca agggcgcatc caacccggcg
    24721 atgtcgtgat gtatcagacg tatttcacga cgatcgtcaa ttccgtttct ggaatgatca
    24781 cgctgattcc tacgatttca aaaggcatgg aatctatcac ttctattggc gaactgttga
    24841 ttgctggcga tgtagaaact tatcacggta agaaaaaaat ccaacatttg gatggaaatt
    24901 ttcgttttga ggatgtttct tttctttatc cggactcact caaaccgatt atcgatcatt
    24961 tttctctaga ggtgaaagct ggagaaacaa ttgcttttgt tgggccatct ggctctggaa
    25021 aatctacact ccttaactta ttgattggat ttatccagcc gacttcagga aaaatttttc
    25081 tagatgatca gcctttggat gaactggata tgcgaagtgt gcgaaattat ttagccgttg
    25141 ttcctcaaac cactttgttg ttctccgctt cgatcaaaga gaacatcact tatggcttga
    25201 aaaacgtatc aaaagaacgt ttagatgaag tcatcgaagc tgcgcaactt tcttcactga
    25261 ttgaccagct tcctgatggt ctggatacct tagtaggcga acatggcaac aagctgtctg
    25321 gtggccaaaa gcaacgtatc tccattgcac gagcgttgat acgtcagcca aaaatcattt
    25381 tgctagatga agcaacctca gctttagata accagtcaga gaaaaaaatc cagcaagccc
    25441 tgaattacct gacagaaaca cccactactt ttattgtggc tcatcggctt tcaacgatca
    25501 aagaggcaga taaaatcgtt gtgatcgatg aaggaaaaat cgttgaaata ggtacttacg
    25561 aaaaactgtt agctcaaaaa ggctatttct accgcttgaa aaatgaatga caaaaaatag
    25621 gagctatgac aagacttttg tcgtagctcc tatttctgaa taaacggtgt tctcctgcca
    25681 actcctcggt cacaagtcac aatagtcatc aaacatgaga agctgttttt tgaaattgtt
    25741 ccttgtaact cagagttaaa cggtaggctc acgacctctt ggtaaatggt gttcaagaga
    25801 cagcctatcg gcaataagaa gcaattttgt catcgctcaa ggccgaacgt ctctttcaca
    25861 ccctctgttg tttcataaaa tagttttatt cgctgtaaag gtcgcgaact ggtgtcatga
    25921 tgatacggtt caagtcattg atgattgtac tgaagccttg ctctttttgc atcaagtcat
    25981 tgattacttc ttctgattgg attttcacag ccatttcttg tgctttcatt gcatcttcgt
    26041 cgctgaactc ttgtccactc atttgttttt cttgtaattc gatttgcatc gcttggaagt
    26101 ctttgaacag tttgtgtgct tcttcgtttg cttgtacttt ctcgtacgct tctttcaacg
    26161 ctttgaattc tggtaattca cggatctcac gttcgatttg attcgcgcta tcgtagatgt
    26221 ttgacatgtt atgccctctt ttcttttagt agttactctc tattgtaaca tggggttatt
    26281 cgttttcaaa ggggctactc tccttgatat ttccgccaga ggtctttagc cgcttcacca
    26341 attccctgaa cgccttcttt caccatatcg ccgaagtttt tcagcccttc ttttgcttgt
    26401 tcaccatatt gattcaagtt atcttgccaa tttccagact ctccattaga atttcctgtg
    26461 tttccaactt gatctgcagc taccacttgt cctcctgtgg cataggcatc tgctacacta
    26521 aatcctgttt ttgaagtata cggaaggatg ccttctgccg ctgatttgaa gactttcccg
    26581 acaacatttc cacttgtccc ttccaaatag tgcagcttgc tggattcttc gtaacccatc
    26641 catgtcgaaa tcactacgtc tggcgtgtaa ccgatcatcc attggtcatt tgcttttgtg
    26701 gcatcgaaat tagtttctgt ggttcctgtt ttccctgcta tcgtataacc tgcaggattc
    26761 gcagcagccg ctgttccatt tgaaaatgta ccaagaagca tgctggtcat ttcatcggct
    26821 gtttcctttg atatgacctg ttttggtttt ttgtttgtgt tatcgacgat caccgctcca
    26881 gtcgaatcaa cgattttcgt gataagatgc ggcgtataca tctgaccatc attggcaaat
    26941 gcactgtaag cacccgccat gatcaatgga gatactcctt tttccagtcc accaagggct
    27001 aagccataat acttatcaga ttttgctaaa ggcaggccga attcttctgc tttatcatat
    27061 cctttttgta aaccgatctc atgcaaaagc catacagtag gcaaattcaa actttgtgca
    27121 acagcttgat acatcggtac ttctccttgg tatgtcccgt caaaattatg cgcatcgtaa
    27181 taactttgcg gttcgtcttt caagatactg gaaggcttgt atccagcttc cagtgctggt
    27241 gtatatacgc ttaatggttt gatcgttgat cctggtgaac gacgcatctg tgtagcaaag
    27301 ctgaatcctc taaagacatg atctcctctt cgtcctacta gtgcttgtac accacctgta
    27361 ttcggatcta aagctactga agcagattgg accatggcac catctgaagc atttgctggg
    27421 aataatgcac tgttttgata agtagcttct aattgctttt gataatcctg atctaaagct
    27481 gtatagattt tatagccttt attcatgaca tcttcttcat caagaccata ctcgttaact
    27541 gcttcatcga tcactgcatc aaaataataa ggataacgat aaccagaatc tgaattatcg
    27601 tatgtgtcat taagatacgc gctgatatct gtctggcttt ctgcttgttc ttgttctttt
    27661 gtgatttttc cgttttcttc cattacactt agtactgtgt ttttccgatc attcgcattt
    27721 tttgggtgat cgatcggatt ataaatacca ggacctttca gcattcctgc caaagtagca
    27781 gcctcagaca gcgtaacatt cgttgcatct actccaaaat actttctgga agcgtcttgg
    27841 acaccccata ccccgttgcc aaaataggca ttgttaagat acatggtcaa gatttcttct
    27901 ttgctgtact tcttttcgat ctcgattgcc aaaaataatt ccttcgcttt tcgatcaaac
    27961 gtttggtcta atgtcagata cgcatttttg gcaagctgct gagtgatcgt acttcctccg
    28021 ccccctgatg ttccgccaga caagaccatt cggactgctg cacgggcaat ccctttgata
    28081 tcaaacccgt gatgctcgta aaaattccta tcttctgtcg agattactgc atcttggata
    28141 tagggagaaa tcgcgtttaa ttctacatat gttccttttt gggcgtacag tgtgccagct
    28201 tcttcgtttt tcttatcata aatgactgtc gattggctta atcctgattt taacgtttcg
    28261 acatttgctt gttttgctaa aataaagagg tagatacttg tcactaagac acagatcaaa
    28321 ccaatcagca aaatcaattt gttcacatga tattttttcc agatgcgctt tcgccatcga
    28381 tggaattgtc cgagatatgg tctgatccaa cgccaaaaac tgatcaaagc agcttttatc
    28441 ttttctaaaa tgctttgaaa atccatttgc ttcttctcct gtctatttga ttcaatcgtc
    28501 ttattttacc atagtgaaag agtgttttct tcctgcttaa gttgtagttc aatatgtttt
    28561 tttacgttag tgcaagtaga gtaacataag aatgaacaga aaaatgtaag ttttttctta
    28621 aatatgtttt aaaaatggta caattagtct gcgattgcac tgaaaggagt acacttgtga
    28681 aaatcacgat cactttacct atgaaccatc ctgaaacaac aattcgcgac ttgcttgaaa
    28741 aggaatggtt agttcctaga aaggttcgac actttttgcg tatacgtaaa aacgtttgga
    28801 tcaatcaaca acctgctttg ttccatcatg aagtaaaggg caatgaccag atcacattgt
    28861 tattcgaaga aacagattat aattatcaag aagttcaatt aggagatgcg aagcacatcc
    28921 gtgttttata tgaagatgag catttgatta tagtggataa gcctgcagga atgaagactc
    28981 atccaaatga accgacagaa aacagtacct tactcaatca tttagctgct tatctcgaca
    29041 ctaaacagca acgaccttac gttgtccacc gcttggacaa agaaacaagc ggtgccgttt
    29101 tatttgcaaa aaatccattt gtcttgccga tacttggaag aatgttggaa caaaaaatga
    29161 tctatcggag atatcaagcc atcgtatggg gagaaattgc caaagatatg accatcacca
    29221 ataaaattgg acgagatcgc catgatcgga gaaaaagggt cgtagatgat aaaaatggtc
    29281 agagcgcctt gacacatgtc actgtcaaca aagtactttc tgaacaaaca caagtctatt
    29341 gtgttttgga aaccggacgt acacaccaga tcagagttca tttagctcat aagggacatc
    29401 cgatcgttgg agaccctctc taccaaaata gaacagctga acgactgatg ctccatgcat
    29461 tagaactgca catgatccat ccatttactc aagaaaaaat agtcggtaaa gctttacctg
    29521 gattatggga atagaaataa aaaagaacag agtcttatca gcagataatg ataagactct
    29581 gttctttttg tgtaatttgt ctgcttactt ttgatgttcg tgttctgcta acagcaaact
    29641 accgataatc ccactttcat tcggcagtcc ccaacgaacg atatattcac ttacttgagg
    29701 tgtttccata taaccaccca tcaattcaac aaattgctga cggatttttt gaaggagatg
    29761 atcctgattc attaccccac cgcctaaaat aatcttttca ggtgctaacg tcaacgtata
    29821 gttgatcagt gcttgagcaa tataataagc ctgaatagcc caaacaggat gatcttgcgg
    29881 cagatcttgc cctttgatcc ctgtgcgtgc ctcaatagac ggtcctgctg ctaatccttc
    29941 taaacaatct ttatgataag gacaagtacc ttcataatgg tcatctggat ggcgtttcac
    30001 ccaaatatgt cccatttcag gatgtgcgat ccctgaaaaa atttcttcat tgatcacgac
    30061 acctgcaccg attcctgttc ccacggtaag gtaaatacaa ctattttttc cttgtgctgc
    30121 tccttgcttc aattccccat atgcagcagc attgacatcc gttgtccaag cagcaggaat
    30181 attgtagcgt tccttgattg tgccaagaaa atcgaattgt gcccaccctt ttttgggagt
    30241 tgccaaaacg tatccgtaat tatcttttgt tttgtcgata ccaatcgggc cgaatgagcc
    30301 aatcccgatt cccttcaatt cataacgatc aaaaaattca aatacctgat ccaatgtttc
    30361 ttctggtgtt gtggtaggga tacttaattt ttctaaaatt tctccaccat ctgaaaccgc
    30421 acacacaaat tttgttccgc ctgcttctat tccgccatac attcgttttc ctcctcgaat
    30481 ccgattgtcc gaatctcata aggttggatt attgggacaa ccgcttgctt cgttggttct
    30541 tcaagcagat tcaatatgac agtttttcca ttgtctttag ttatttccaa tttttctaaa
    30601 tgactagaca tattgaaacc tcttactact actttatcac taaacttgct gcgtttcaaa
    30661 gctgtaattg caaacgtttc actttttatc gttaaatatt gttgttttga aatcaatgtt
    30721 ccttcatgat gtttgatttg ttgagtggaa aaaggaatct gtgctgcgta tgcatgcaaa
    30781 taagtagaga atttttcttc tggtccatgt agttcaatgc tgtaattgaa ccgatgctca
    30841 cctagacact gtgcttctgg tgttggaaaa tatccccaat cgcctagttc tcccacactg
    30901 cgaagtagcg tcactgcgat ttgtccgtct tctgttactt catattcatt caaaccaaag
    30961 tttccgactg ttacaccgta ctcttcatca tgaatattga caaatgcttg ctgatgttgc
    31021 ggattcgtgg ggttttccca acttttagac acatggtttg ggcgcttcac cacttcaaaa
    31081 atactatctg cttcgtgatg ttccacatgt aactttgtag gaaacaagac acgtaagcga
    31141 tgatctttca tctgattgtc gagagtcgtt tcaaagtcga tttttttact atcttttctg
    31201 attgtcatga ttgtttttat ttgaaggatt cgtttttctt tggatcgttc tgcttttcga
    31261 taacgaaatt ccacaaccat ctgctgttct ttttctaaac gctcgtctgc agaaacaggg
    31321 atttccattt cctgtagaat acttattttt gctatttccg gtgtatctac taatactttt
    31381 acttcagagt tttctttgtt actggatagg attggctgat cacagaaagg ttgtttaaag
    31441 atatactcat ttcctatatc gccgatatct tcaaaaatat gcagattatt caactttcgt
    31501 ttgtttttgc gatcttccat tgtaatggta ccattttttt caatcgtcaa atgtagaggg
    31561 ccgttttcga tgattcgtcc actctgatga atcattgttt ccttttcttc tgctttcgct
    31621 tccccttcta caagcgcgaa tgtttcccaa gaaaatgctg gcatgttttc taatggtaaa
    31681 gtcactttga tcattcttgc catatatggc acacggaaac ggtctttcgg caaatcataa
    31741 ccaaattgga cagtttcttc agataaaata gctggtatag tggccccact ttttgtttct
    31801 acatgatact tacgtttagg caaattttct aactcttgat atagttgttc aggtattcct
    31861 tcagcgaatc tttttctttc taattcgatg gttatttctg cttcaccagt tttatccatt
    31921 cctgcagtat ttacaatgac aaatggaaag ctgtcttttg ggaatccggt cgtatcgatt
    31981 gctgcggtca gctgttctaa ggaatcttgt gcaagatact ttccaacttc atctgctttt
    32041 tcaaaacgag gtatcatttc ccgatggaca gaatcgactg aacaaccgca aatactgtcg
    32101 tgaggatgat tttgcattaa tgtcttccaa gcataatcta attgatcatg gggatagttt
    32161 ccactaactt cataagccat cgtcgcaagt ggttctgtaa tattttctag ctgtcgctgg
    32221 accttggtat tccattgttt taagtaaacc cgagcagatg ctgtattggc taaagtatac
    32281 cagccatccg tttcttgact tgtcaattct ccttctactg agcctaagtc ttctggcaca
    32341 tctttttgaa ctgcttccag atagtcagta aaattagaat gaataaactc gtaatctgga
    32401 aacagttcat ttgcgagatg gattgctttt gatatatctt tttgtaccgg ttgatgatca
    32461 acaccattca tcatcaataa gtggttcgta gaggcatatt gttctgcatc cgctaatttt
    32521 tgcttccaaa aggcaagagc tgcttctttt tctactggaa tctcattccc gttgctatac
    32581 caattggcaa atagcagacc aaagattgct gtttgatcag gtcctttcca ccacatctct
    32641 gagtattggg aagaatagtt ttctgcttcc aaaacttgat tatcaaagcc aattggtttt
    32701 acaccacggc caaacgctgc tgctgaaata ccagcttgtt tcattaattg aggcgtctgt
    32761 cccatatttc caaatgtatc gggaaaatag cctaacatga caggggttcc ccatttacgg
    32821 ctttcttcca tgccaatcag catatttctc acgttcgatt ccgagctgat aagaaaatca
    32881 tcttgcaaga tataaaatgg tccaattctc aattttcctt cattgattgc ttgttggatt
    32941 gcctgtcttt tttctggcct tacttgaaga tagtcatcta aaataatcgt ttgcccatcc
    33001 aaatgaaaac tgttgaagga cggatcaact tcaaatagct ctagtagatc gtctatcaat
    33061 tcaatcagtc gcatgtgatg ctgttcgtaa gccatgtacc attcacgatc ccagtggcta
    33121 tgagaaatga tatatacttt ctttttcatt tacgatacct cctacttttc tactctaata
    33181 tcaaagtaat ccatgactaa ttcgcaaaac atcatatttg cccaagaaaa ccattctctc
    33241 gtataatttt caggattgtt cacatcgaat ccttcgtgca taaggtgtgt tcctgcgtca
    33301 gttgctacaa gtaaattcaa tatccgctct ttttcagatt tgtctgacgt tgtcattcct
    33361 tccatagcta atgcaatcgg ccaaacgtat ttttctggcg tatgggagga tccaattcct
    33421 tttgcgtact ttccttcata gaaatatgga ttttctttac tcaacaatgt tcttcttgtt
    33481 tgcagataat cttcctcttg ttcagaacaa tatcccaagt aaggtgcggc gatcagattg
    33541 ggcacattac tgtcatccat gactgtggcg tttcccattc catctacttc atatgcataa
    33601 atcgtttgcc ctttttgatt aaccgttcgt ccgtgattct gaatcccctc ttggatctct
    33661 ttcttcaatt tctgtgtttg ctgtacaatt tctttatcat cgagtatcgt ttgaaaaatt
    33721 tcttccacat aacctaacac gaccaccgca aacatattgg atggtaccag atatccataa
    33781 cggcaagtat catcgctagg acggaaacca gaccatgtca ttcctgtaaa agctgttttt
    33841 gcacctcgcc cgtcattgat cagcgtatct tcttttcttg tcgtgtctcg tacaaatgta
    33901 taaggagagt gttcatgatc ttgctctgtt ttgaacacgt ccaagatttt tttgatacct
    33961 tcaataaaag attgattgaa ttgatcagtt tttcctgtat ttttgtaaag aagataggcc
    34021 aactgtattg ggtagcataa agaatcaatt tcatattttc tttcccagat ccaatcgttc
    34081 atttttgtat gatctgtttg gtggccagca ccgttagctt cttcgttgaa ggcattcgca
    34141 tatggatcga tattgatata aaaaaattgc tttttgacta acccgctgat catgtcagct
    34201 aattcctcat cttcttttgc aatcactaaa taaggacgaa cttgtgcagt agagtctctt
    34261 aaccacatcg ctggaatgtc tcccgtcaat aaaaaggtgg ttccgtcatt ttgctttttg
    34321 actgttgtca acagagtatt ggcaaatgct gctgtaaaat tctttgccca gtccgcatgg
    34381 atatccccac atttttgtgt gatatcttcc ataaatttct gcaccgattt tggtatatct
    34441 ttataagcca ctaataaaac cttctttcta tttgatatat ctttaaagat tatacttcat
    34501 acagccaatt atgtctacgc tttcaaaaaa tatcttttta tttacttttt catccattat
    34561 ggtattattt gaatatgata tatcattaag aggtgtttat atgaatcaac cattgtacca
    34621 gacaatattt aatgatttgc aaacggctat tttaactggt gaattacctg tagacagcca
    34681 actaccaact gaaaaagaac tttcacgtac ctataaagta agcagaatca cttccaaacg
    34741 tgcattgact gaattagagc aattaggact tatttatcgc gttcgcggga aaggcagttt
    34801 cgttaaatcc gcttctccgg aacagattct tgcttctcct acaaaaacac gacggattct
    34861 gtttcttctt ccatatgtcg ctgatttgtc tgttggtgat tttagcaagg gattgaaccc
    34921 tgtgatgcaa gataaacaga ttgatgtcat gatgacgacg cttgactttc tacaaaataa
    34981 aacagcaaaa gagctaatca atgaatttga cggattgatt tattatgctc ttgatacaga
    35041 acaacatctt gacttacttt ttgagctttc attgaaagaa ttccctgtcg tcatattaga
    35101 taaaaaaatc tatgagttac cttttcctac cgttctttcc gataatttcc aaggcggtgc
    35161 gcttgctgcc tcttatttga tcgaacaggg acattcaaaa atcgcttatt tgtttggtac
    35221 gcagactcat ccacaatccg ttcgacagcg ttaccttggt taccttgaag cattggacaa
    35281 agctggtttg actttccaca cttcactgga tgacaaaagc gcgacattag atgaattgct
    35341 ttcttatatc actaagtatg aagtaactgc ttttgtttgt gaaaacgatg ttgtcgctat
    35401 ccagaccatg aatctcttga gacagcatgg ttatcatatc cctgaagatt tttcaattat
    35461 cggatttgat gatatccaag cagcagctct tgttgacccg ccactgacaa ccatcgcaca
    35521 agattttgaa cagttaggta agcttgcggg agatgctttg gtcacttggt tagagacaaa
    35581 agatcgacca tccgatagta aatttccagt ttcattcatc aaaagacaat caacaaagga
    35641 gaaataaaat gaatatcggt caaatagata ctagacatgc aacagcgaat cagccaaatt
    35701 tctctaatgg gaactgccag ccttatactg gcgttccttt tgggatgaat tattttgcac
    35761 cgcaaactac ggatcaaaac ggcagctggt ggtttcatcc tgatgaccgc gtttttcaag
    35821 gctaccgtct tacccatcaa ccaagtcctt ggatgggtga tttcagtcat atgctgttta
    35881 cgccgatcaa tggaaaacta caggagaaca cccttttcca tgctcaaagt tcttaccgcc
    35941 cagaagaaag tatattttgc ccgactcatc tgtcgatctg tcaattacgt tatggcatct
    36001 gttctacatt gatacctagc atgtatggcg gaatcttatc tattgattac agcaaaaatg
    36061 acagcggttt acttttatcc tttccgggac gccatcagct ctttgttata gatccttaca
    36121 cagtggaagg aaaaatcaca cattttgctg gttcagaaga tcctgatttt tctttttatt
    36181 ttatattgag atttgaatat cctttaacaa ttgatgagtt agctgtttcc aacaaaaata
    36241 gcgactcgat cccgttgtat tttgaacaga caaaaaaaca aactatccga tttgggacat
    36301 cttttatcag ctcggaacaa gcagcttata acctggaact agaacaaaac caaagcaaag
    36361 agacttacct tgctcacagt caagaacaat ggcagtccta ttttgatcgt atacagctca
    36421 cacaccatga tcaacaacaa ttgcggacgt tttatcataa tttatatcgg gtgtttttat
    36481 ttccacaaac attttatgaa attgatccta gtgggcaaaa aatccactat gatacgacta
    36541 gtcgatctat aaaacctggt gttctctata caaataatgg gttttgggat acgtataaaa
    36601 cggtttatcc tctttattct ttgattgctg tagaaaaata cgaagaaatg ctggaaggtt
    36661 ttttgaacag ctatagagaa agtggctatt tgccaaaatg gctgtctcct gatgaacgtg
    36721 gacttatgcc tgggacattg atcgatgcgg tcattgcaga tgctgctgta aaagatatcc
    36781 gacgagactt gatgcctgaa tttctaacgg caatggaaaa aggtgctacg gttcaaagca
    36841 aacatccaaa ttatggacgc caaggaacag aagattactt gacatatggc tatgttccta
    36901 atcactacca cgaatcagtc aatcacacat tagactatgc ttatagcgat ttttgtatta
    36961 gccaagttgc caaggtacta gaagaagagg aaatgacgaa gaaatatcag cagcaatcat
    37021 tgaactatca aaatatcttt gactatgagt caggatttat gcgttcaaaa gataaagatg
    37081 gcaagttcag agaaccattt tcagctaatc gttggggaca agattatgca gaaggaagtg
    37141 cttggcaaag cagctttgct gtttatcacg atttttcagg actgatcgga aaatatggtg
    37201 gcagtgagag atataaagaa aaactcattg agctgtgcaa tcagccccca acgtttgacc
    37261 caggaggata tggttttgag atccacgaaa tgagtgagat ggccgcgata gaatttggac
    37321 aattagctat ttcaaaccag ccaagttttc actatcctta cttgttcagt tatataggac
    37381 aacctgaaat ggcacagcca ctgcttaaac agttgatgac tcagaccttc gacgattctc
    37441 caatgggtta ccctggagat gaggacaatg gaagtatggc cgcttggtat atcttcaata
    37501 gtctgggatt ttatcctgtc acgcctggaa ccggtgaata tgttatcggt atgccattaa
    37561 ttgacaaggc tgttttgctt ttgtcaaatg gaaaggaatt gacgattgaa gcaacgccta
    37621 atcggccgca gcaacaattt atccataaaa tcaaacggat ggacaaagaa tatacgaaat
    37681 tatattttac ccatcaagat ttgctgaaag gcggcacgat ctcttaccaa ttagggatca
    37741 tccctcaccc taagaaatat caagcaaaag atttgccttt ttccttatca aactataatt
    37801 aacaagaggt tgtgaaaaag ctgtcctgca tcaagtaata agaacagcca agcaaaaata
    37861 gatcctcata tttttcgttt ggttggtctt attaccgcag atgcaagctt ttgaacaccg
    37921 tttattgaga ggttgtgaaa tcagcgttct gacctgagta ttagagagac aaatggcaaa
    37981 atagttcctc atattttgcc attttttgag ctaataccga gggtcagctg attgaacacc
    38041 gtttagtgga gaggtcgtga aaaagctgtt tagtttcgag tattaagaaa aattttgtga
    38101 aaatggcttt ccacattttt gcataaattt ggcttaatac cgagaaactg gcttttgaac
    38161 tccgtttatc gagaggtcat gaaaaagctg ccttgcctca agtaataaga acagcccaaa
    38221 attagatttc tagacaattt tttataagtt atttcattac attggctttt tcttttatga
    38281 ttctccactg ttttctcggt actctttagg ggatctgccg acgattttct tgaataattt
    38341 agagaaatac gtggtgttgt tgtagccaat ctcacttgct atctcattga tgttttgatt
    38401 actgtgcaaa agcagttgtt tcgctttttc catacgtaaa tggttcaaat aagctgaaaa
    38461 actttttttc gtttcttttt tgaacagctg tcctagatac atgacattta aatgcaggtt
    38521 ttctgacact tctttgagtg taagtggttc ttgataatgc tggtgcagga ttacgattac
    38581 tttttccaca ttgtcactgt actttttctg tctctgatgc tttttgatga atgacagaag
    38641 tagctgctga agttcttgca ccgtttttgc ctgatggatt ttttcgattc cttgtaaata
    38701 ttcctcatct tccagatcaa tcaattcccg ttgaatctcc ataaacagta aaaaactgga
    38761 atatcgtata tcttccggca tcatggctgc taactgaaac tgttcaaaaa aatcagtgat
    38821 cattttttga gcgacttcca attgtttatt ttgcagcacg cgtctgaaac ttgaaaaatc
    38881 gatggtttga tcttttgttt ctgcttgtac tgcgtaaaaa acatgctcgt ctttatctcc
    38941 ataaaattga tgcaactgta gattgtcttt cgcttgttgg aatgtttcag ggattttgtc
    39001 caaagaatct gtctcttccc cgatactgat cagccattcc tgatcaggaa agttttcttg
    39061 aacaaaacaa cagaagccat caacttcatc tgcctccaac aacaacgtga tcaatacacg
    39121 gtctccgtaa tttcgttgat agtaaaagat ttgttgccgt tcttgcaacc atctattgat
    39181 aagagtatca tgagttcttg ccagttgaat caatactatc ctatgctgct tctcacttat
    39241 ttgtcctatt atttcttctt cacttatttc atccaattct tcattcaacc attgactgaa
    39301 taacagttct tgatagattt cttgttgatt tttttgttca ttttgctgat ctaaccgtgt
    39361 tttgattttc ttgaggcttt caaccaattc gaacttattc acgggtttca tcaaataatt
    39421 cacggcgcct aattgcatac ctcctttcaa ataatcgaat tcttggtatc ctgataaaat
    39481 cataaattca aaattatgac gttctttttg agccgcttca ataaattcca gtccatttat
    39541 ttctggcatt gtcacatccg ttactactaa atcaatctgt cgctgttcaa gtacagctag
    39601 tccttctttg gcattctctg ctgttgctac tatttgaaag cctaaacttt gccaatcaat
    39661 tatctttttt aacccattca aaatcatgta ttcatcatct accaataaca cttgatacac
    39721 gctcatccct ccttgaatgt aatagaaacg gtcagtccac ctgtctcatt attctcaagc
    39781 gacatataat aactgctgcc gaagctggca cgtaaacgtt cattcacgtt ttgcagaccg
    39841 atagaaccgt gaagttccac tttaggatga gacagttttt cttcaatctg ttttagccgt
    39901 ttttcagtca tcccttttcc attatctttg atgatgatcc ttacccgttt gccttcctgc
    39961 aagactttga cacttagcgc attatcgaat cgagtaaaat caataccgtg tttaaaataa
    40021 ttttcaacta atggctggat cacaaattta ggtacttcga tcttttccaa atcaggatcg
    40081 atcataaaat gataggctac tcgattagga taacgcattt gatacaaata gacatatttt
    40141 tcgcaaaagt ccagttcttc ttttaaagtg atcgttttct cttgattcgt attgtttcga
    40201 agcaaagcgg aaaacgcata cacaacatct gctaattctt cacttccttc gctgattgca
    40261 tacattcgga tatattctaa tgtattatat aaaaagtgtg gattgatctg tgcttgaagc
    40321 gcccgcatat gtgcgtcttg ctgtttgatt tctaatttgt agatgtcttc tacaaactga
    40381 ttgatgctat ccaacatttc gttgataccg attgaaagtt ccttcagttc atattccgtg
    40441 tttgttatgt cgatccgcgt ctctaaattc cctgctgctg tttgatccat ggcctgcatg
    40501 acgatagata cttgctgtga atatcgtttg aatgttttat aaagaaagat aagcagtata
    40561 ttgtctaaaa taatgatacc aatgatcagc ggggcaagat tttttcccgt ttcgattttt
    40621 acactttttt tatctagtac agctaatata cgataatcat cagacagttc ttggtgttga
    40681 acaaaattgt ttttttccag atcgtcaatc ggcaattgtg aatttttctt cagactctct
    40741 gtgatgatca tttcttgtct ttcaaacgtt tctttagcta ttttattatc atggaatgtg
    40801 tatagtcgat ttgtcgttcc agaaatcatg tataaagaga gtccattgaa tgacgttaga
    40861 ttttctaaaa tcatatctag ttctttcttt tgaaaaccaa taaaaatact tcctgactca
    40921 gctcctcctt gtgtgatagg caacttgata taaaaggcgt ctagtaattt tggtgtcccc
    40981 ttttttattt ccccaccttt gttttctcta gaagattcat aatactccgg tagttgattc
    41041 aacacgatat atatcgcact tagttcttca taatttgcgt agagatcttt gatttgattt
    41101 gggaaagaaa ctaattcatc ggtactgttt tgctgttcgt atacatacat cagatactga
    41161 tctatgggtt ttgttaagta ggtcgtcaca ttttcgatct tttcggaatt ccctacaagc
    41221 tggtttttga tgatcctact caaggttgtt ttatcattca gcattctgct tgtgctttga
    41281 acggcatcac ttgtcatgtt ttctgcctgt ttttgatttt gttcccaagt atggatacta
    41341 aaaataacgg tagcagtcat cgttacaccg atcatgataa ccgcgtattt ccgcaacaga
    41401 cgatttagta aggttccttt tgaaaataga atccgaaact tattcataac tttccaactg
    41461 tttatctaat tcttcacgcc aatgtgttgt catcgtacca ttccaaaccg tcaaaagacc
    41521 aatgacacca aacaggatca atcctttgaa ttgccaagtc acgcctaaaa ttataccgct
    41581 accaataatt atttttagaa aagacgaaaa gctggaaaaa accgaaataa aacttagctt
    41641 tagcagatta ggaacagaga tcgtatattc actatctaaa atcatactgt attgataagt
    41701 agcaaatagg cagagcaagg caaaaagtaa aataaaatca atagctaaaa aaatgagccc
    41761 tttgatttga acagataaat ataaattgta actcaataaa gcagtaccag ataaaaataa
    41821 actaaatagc agattgcctc ttaaaaaatt tcttttatat atattccagc ctctttttat
    41881 tgtgatttct ttatactcga atccgtacaa ataaaatagt tcattgactg ttttccatgc
    41941 cgcacctaat ccaaagatga tcccgccggc aaatgtatat atccagaaat acaaggttag
    42001 ttttataatg acccagatcc ggataaataa ctcttccaaa accttcccta acatatcttc
    42061 tcctccaaac attaagttta tactttctca ttatacaaaa aaaggttggg caatcagcac
    42121 cttgacctga ttattagaga aacaaacgga aaaatagttc ctcatatttt gtcgttttgt
    42181 gagcgaatac cgagggttag ctgattgaac accgtttacc aagagtttgt gaaatagccg
    42241 cttagtttcg agtagtaaga aaaattttgt gaatatggct ttccacattt ttacatatat
    42301 ttagcttaat accgagaaac tggcttttga acaccgttta ttcggaacaa gaggttgtga
    42361 cacgtctttt gtcacaaccc ctttgtcttt attcattatt attcttgtcg gaactcatca
    42421 tattgttttt gcatttcttt caatacctta tcatagccag ccttgtccaa agcgtctttc
    42481 aatttcggta atgtttcatc tggatcaaca gtccctgtat tcaatccatc taaatattga
    42541 ttcatgacat tagaaatatt acttaattct gttttgacac tgtcagtgtt gaagctgaat
    42601 cctaaaatcg gtgaagtttc tgcatcagca atcgattgat cacgtttggc aatcatgtca
    42661 tccgtaatag actcttgtgt atatagaatc ttgttgtttc ctgtattcca agcagacata
    42721 tgtgtatttg gctgataacc atctagcaat ttgattttat catctgaacc atcgactttt
    42781 tcccatgctt ctccctcgat cccccaaaca agcccattca ataattctgg atcactgtta
    42841 agcagcccta gaagttctac tgatttttct ttattttttg aagtatttga tacgacaaaa
    42901 tttgccattt gtgcttgagc tgtagatttt agtggaacag taattgcttt tgagacaagt
    42961 tcttgttttg ctgcatttgt caaaattgta tcgccataat catacggtcc ttgtgtttct
    43021 ccacgcatta gccaagtatt tccttctagt ggataatcct tattgctcgt tgcagcgtca
    43081 cttggaatga gtccttgttt gtaccagcta tgcattgtac gtaacagtcc gatatacgtt
    43141 tcattatcgt attggttgat gattttcgaa tcatctccat ccagatcaat agcaaatggt
    43201 aacgtattcc ctaaaggata atcaaagttc ccttggactt tgaagccttg tccaatggca
    43261 aaagctgccg tgtttggttc tttttcatgg aattccttca agactttttc tgcatcagcg
    43321 taagattgga ttccatcaat tgaaagatcg tatttatcta gtaaagcttt gttaaaagta
    43381 agtacttgtt gagcaaagac atttccattg actgggaaag catataattt tccattgacc
    43441 agatttcctt taatatatgc ttcatctaaa tcattataag ctttttcagc gtacttaggc
    43501 gctaattcag tcaaatcagc aaaggctcct ttttgggcat tggaaacata gttgttcgca
    43561 aaggcgatat cataattttc cccggaagaa atgatgacgt tcattttctt ttcgtaatcg
    43621 ccccagccaa tgtaattgat attgactttt acaccgatct ctttttcgat tcgtttgttt
    43681 gctacttcca tcaattgatc gaaattatct ggtttatctc cgatttgata catctgcaaa
    43741 gtgtccgaat tgctagcttc tgcctggtct ttagaaccag aacctccgca tgctgctaat
    43801 gttcccaaca acaacgctga aacacctgta aaggctagtt tcttccataa cttcattttt
    43861 cttcctccta attttatgat ttatattttt gtttctttat tcttttactc cgccgattgt
    43921 tagacctttg acaaaatgct tctggaaaaa tggatagctg atcgcaatag gcaacgtcga
    43981 gatgactacg atcgccattc tggcagattc tcctggaact gaggctaatc cgcctgtcaa
    44041 ttggcttcct gctcctgaat tttgtgtcag atattgaata ttactttgga ttttcatcaa
    44101 aagatactgt agtggaacta gcttatcatc ttggatgtat agtaaagcat tgaaccagtc
    44161 attccagtaa cccaatgcgg caaataaact gattgtcgca atacctggaa cagctaacgg
    44221 taaaacgatc tgaacaaata ttcgcagttc gctagctcca tcgatccgtg ccgattcaat
    44281 aatcgaatca gagaccgaac gtttaaagaa tgtgcgcatc acaataatat tgaagggact
    44341 gacagccatt ggcaagatca atgcccaaat cgtatctttt aactgaagaa gatttgtcat
    44401 aacaagataa ttggccacca tccctggtga gaacaacatc gtaatcaaac aaaaaacggt
    44461 aaaaaaacga cggaatggaa agtttgaccg tgaaatcgca taagcatata aagaagtagc
    44521 cgtgctattg atcagtgtac ctaaaacagt aacaagtaca gtgacgaaaa gcgcttggaa
    44581 aattttatcc tgcatctggt cgaacaagta cgtataacca aatatactga acttttctgg
    44641 ccaaaaactg tacccgtgag tcgacaatat ggactcatcg gtaaaagaga tggcgataac
    44701 aaatataaat ggcaaaatac aggaaatagc aaagagtgca atcattatat tagagaaaaa
    44761 attagccgtc ttattgaaag agcggacttg gactctctcc actttctttt ttttcatttt
    44821 tttcctcctt agaataatgc agaatcgcta tcaaaacgtc gggcgatcgt atttgtgatc
    44881 atcaacaaga caaagccgac aactgattgg taaagtcctg cagcagccgt cataccaaaa
    44941 tctcctgtgg atgtcaggcc attgtagata tacgtatcca aaacttgagt cacatcatat
    45001 aatgcaccgg aattcctagg aatgttataa aacaggccaa aatcagctcg gaaaatgttt
    45061 cctacggcta aaatcgttaa aatcgtcatt agtggaataa gttgtggtat cgtcacatgt
    45121 ttgatctgct gccatttgct agctccatca accatagcag cttcataata agtcggatcg
    45181 attcccataa cagatgcaaa gtaaataatg ctgttataac caatcccttt ccatgtacca
    45241 atgaacacca agataaacgg ccaatatttc ggttcattat accaattgac agcttctcct
    45301 ccatgtccag tgatccactg attgaatatt cctttgtcag gacttaaaaa agcgtaaaca
    45361 aagtaactga taatgaccca agatagaaaa taaggtagta aggacatcgt ttgataaact
    45421 ttaacgagtc gtttatttct caactcgctc ataatgattg caaatacgac tgagatcagc
    45481 agattcaaaa ggataaatgc tacattatat aaaattgtat ttttagtgat gagaaatgct
    45541 tgatccgaag aaaataaaaa tttgaaattt tcccaaccca cccaaggact ttccctcaag
    45601 ctagccaaga acccatctgc tgaaatatga aaatttttga atgctacgac attcgccatt
    45661 acaggtatgt aaaagaaaaa aatcatccaa agcatacccg gtacagccat caggacaagt
    45721 gctttataac gccatagatt cataaaaaaa tgattgaacc cctttcgttt tttcatctaa
    45781 aaaccccttt cgattcattc gcaacgtaat tatagcgctt tcaataatga gaataaataa
    45841 acaaagtata gggaaaatga aacaaagtat aggagaggtt gtgaaatcag cgttttggcc
    45901 tgagtattag agaaaaaaac gggaaaatag ttcctcatat tttgccgttt tttgagctaa
    45961 taccgagggt cagctgattg aacaccgttt atcagaggtt gtgaattcag cgttttggcc
    46021 tgagtattag ggagatcgtg tccttactat ctaactctga gtcacaagga acaatgggga
    46081 ctgtaacaaa agtcttgtca cagtccctta ttccgaacaa acggtgttcc agaagtagct
    46141 tctacggaaa taagccgaaa tttcacaaaa aagccatccg aaagtcagac ggacaagtct
    46201 gcttttcaga tggcgctaca actactctgc ttattctttt agctatccat tcaattattt
    46261 ttctctcact tgttctagct cttctttggt catgggtcga tattgccctt tattcaaatc
    46321 tttaggcagc caaaattttc ccatacggat tctttttaaa tataagactt cttttcctac
    46381 tgctttgacc attcgcttaa cttggtgaaa ctttccttca tgcaaaatca gacggataat
    46441 tgaagtttct gtctcttgat ctacttgatc aatttggagt tttgccggca atgtctgctc
    46501 atcgccatca ataatcagtc cttctgcaaa taaacggata tcttcttctg tcattatacc
    46561 gctaacctca gctagatatt ctttctccac atgtttttta ggtgatagta actgatgggc
    46621 aaacaccccg tcattcgtta aaatcaagag gccctctgtg tctttatcta atcggccgac
    46681 tggaaaaaga tcttcccgat aatcctggtc ttccaataaa tcgattacgg tttgatcatg
    46741 attatcctga gtagcagaaa tgactcctgc aggtttatgc aaaatgtagt aaaaatcttt
    46801 ttgatacgta atgatttctc ctaaataagt aaccgcatct tcgaattcat ttacttgcgc
    46861 tttatcgctt ttcaccactt gtccattgac ttcgatcgtt ccttttttga ttaatccttt
    46921 gacttctttg cggctgccaa gtcccatatc tgctaaaaac ttatctaaac gcatgcgttt
    46981 cccccatttc aaaagagcat caatctagct cttctgattc acttatttta tttttaattt
    47041 atgtcgtaaa cgcgctattc ctggtcctag tagtctttct gccaagcgga ttttcaaagc
    47101 taaataacca tacactaaag cccctatacc tgctactaca agaatcaaca atagagactg
    47161 gaatttgcta tcttcgttta aaaaagcacc aaaaatcatc tttgtgatcc acgaagccaa
    47221 aagcataatc aaggtaagaa taaagatcag caatgtcctg cgccagacaa aacttggttt
    47281 aaagcgggct acttcatgga ttctctttaa gatcaaggta caagacacag caaatccgat
    47341 cattgtcgcc aataaagggc cgtatacttc aaataaacga atggctgggt attgaagaag
    47401 gagtttcact agaaacccaa taaccaaata attaattgcc gccttgtttt caaacattcc
    47461 ttgcagcatg ttggaaacta gcatatatag tcctaggaag agtcctacaa aacttgcttg
    47521 gatcagtaca ttacttccta gagaatccgg tgtataaaat aatgtattta gcggataggc
    47581 aagtaacata acaccaaatg tcgccggaaa cataaaaaat gaaaacaact gtaaatttcc
    47641 gcttgtcaat tttgccagac ctactcgatc tttcaacgta acagcttctg taatcaacgg
    47701 taacccagta gacgcgatcg atgttgccaa tgcaataact accatcgtca acttatctgg
    47761 attggcacta aaaatcgaaa aaagatccag taactgtgca ttggaatact cggtggatgc
    47821 agacatgatc ttcataaaag tgaactgatc gactaatttg aagatcgtta cccctgaacc
    47881 cacaataata aacggaatcg cttctttaac ggtatctaac aacaattcct tcgttgcaat
    47941 atttattttg ttttcgctgt agtgaataaa cgccgatgta tacgcttgat gtttcttcaa
    48001 aaaatacaaa aggacaagaa tacttgctag cataccgata aatgccgcga aagttgattg
    48061 cgtgaccgcc gtcacatagt caccatccat gactttcatg atgatgaatg tagccaatag
    48121 catataaaaa atacgtgcca cctgttctac aatctgcgac agcgcataag gcatcatttc
    48181 ttgattgcct tgcaaatacc ctcgtatcac actcatacaa ggaaaaacca atacagcgat
    48241 actcaaagaa cgcatcgttg gaatcagttc ttctccgcca ccagaagcat gagctagcca
    48301 aggagaggcg atgtacatga acaaagcaaa caacaggcct aacccgccca tcatctgtaa
    48361 tgcacggata aataatcgtc gtgaagtgcc atattcattc aatgaattat agcgtgcagt
    48421 ttgttttgca atcgcagcag gtattcctgc tgtagagatc agtagaaaca atgcatatat
    48481 attgtatccc atattgaata atccattggc agccttagca ttttcgccca tccaagcata
    48541 ccagggaatg atatagacag cgcctagcaa tcttgaaatg atattactgg cggtcatcca
    48601 agcagagcct cgtgccattt tttcttgcgg tgttaattga tctaatgctg gttttctttg
    48661 attatccatc ggtcagattc caactttcta caaaacatta ctatcatttt aattggtaaa
    48721 acagaaactg gcaatcgatt ttatataact tttataagaa caattgtttt tttgaattcg
    48781 gtttcgtttt tttggtaaag taaagaaata tacagccttt tatggctaac atttatagga
    48841 gatatcaatg acacaagaaa taaaaaaact acccgttata tttttaggtc ttttctttat
    48901 cacagttgga ttgaattggt tcttgctccc tcacgatata gcttccgccg gagtgggcgc
    48961 catcggacat ttagttgaaa cggccttttc tatccaacgc tcagttactg tttggagcat
    49021 caatcttatg atgctgcttc tagccgctgt cctattagga aaatcagtat tttttaagac
    49081 tgtagcggga agtctgcttt ttcctgttgt tttagagatt gttccaaaag tggaaatgat
    49141 ctcctcacat ttcttttcac tgatttcagg aagtcttttg ttcagtcttg gggtttacac
    49201 attgtacaca gtcggggcct caaatggcgg tataacgata ccgccgatta ttttccacaa
    49261 attttttcgg cttccaatgc cgcaaggact tttacttacc aatagtctta tcgtcttttt
    49321 gaattattat gtttttggat tgttggagac actattcgtt ctcctatcta ttacagtcag
    49381 ttcattgttt atgaaaatac tcatccgctt gtcccctgtg tcaagaaaat ttgaataaag
    49441 ctggattttg tcatagcgga aacaaacgat atattaaaaa gagtgtgcta taataaacca
    49501 agaaattgaa taaagcgagg gatcaatcaa tgagcttctc tttagaagac atccgtcatt
    49561 tactattaaa agaaaatcta ttaaaagaat ttgtttcaac aagaggctgg catcttgatg
    49621 taccagaaaa agctgaattt cttcagttaa gttatgattc aagaaaagct gatgcttcta
    49681 ctttgttttt ctgtaaagga atgaatttca aagaagaata tttggattca gcaatcgaac
    49741 agggtattca atattatgta tcagaacaac catacgaaaa ttcagcagta ggaatcatcg
    49801 taacggatat ccgtaaagca atggcgcttc ttgctatggc tttttacgac tatccgcaaa
    49861 ataaattgaa agtgatcgga ttcactggaa caaaaggtaa aacaactgct gcgtacttta
    49921 caaaagcaat cttggatcac acaacaaata aaaaaacagc attgctttct actatgaata
    49981 caacgttaga tggcaaaaca tatttcaaat cccatttgac aacgcctgag tcattagatt
    50041 tatatcgtat gatgtcagaa gcagttgaaa atggtatgac tcatctagtg atggaagttt
    50101 cttcacaagc ttacaaaaca caacgcgtat acggcttgac tttagatgtc ggaatcttct
    50161 tgaatatctc gcctgaccat atcagtccga tcgaacatcc gacatttgat gactatttct
    50221 attgcaagcg acaattgatc ttgaattcaa aaacagttgt tttaaatcat gaaagtgact
    50281 attttgattt acttagggaa acagccgatc tattccagat tccaacgatc acttatggtc
    50341 gttcggaaga aagcaattat caagtgatcc gttcagataa aggtactcac ggttttactt
    50401 tatcttctca tgaagatcgc ttagctatct gcgatactgc ttatgatatt ttgctggctg
    50461 gaggattcaa ccaagaaaat gcagccagtg cgatcattgc cgcagcacta acaggtgcct
    50521 ccagtcaaga tgcacaagac ggattaaaag aagctcgtgt accaggccga atggatcaat
    50581 tgatccaatc caatggagcg catgtctatg tggactatgc acataattat ctaagcttga
    50641 aaacattgct gaaatttgcc aaaaatgaac atccagatgg ccgtgtaatt gttgtattag
    50701 gcagcccagg aaacaaagca atctcccgtc gacatgattt tggaaaagtg ctatcagaaa
    50761 cagctgacat cgcctttttg acggcagatg acccagcatt tgaagatccg aaaaaaatcg
    50821 cggaagaaat caatgaagca attactaatc cagatttgat cgttcattat gaaatggatc
    50881 gtcctgaagc gattcgacgc gctttagcag aaagcgctcc gcaagattca gtcgttattg
    50941 cgggaaaagg cgtggatccc tatcaaaaaa tcaatggtgt agatgaacct tatgaagggg
    51001 attatgcaat cgtgaagcgg ttgattgaag aataatggta tttatatact agtggtttcc
    51061 catttctaag aaaaaaaggg actgtgattt tttgtcacag ttcctttttt cttagaaatc
    51121 attttaactt ttcactagct aattctgctg ccttttctct ttcttcattt aataatttat
    51181 tatcatagaa tttgataaat gggaaccaga taatgaatgc gatgattgca caaatgactg
    51241 ctaacacagc agctttccaa tcaccaccac taccaacaaa tgctccgatc ccgactggtg
    51301 aaggccacgg catctgtgca agcatcggtt tgacgatttc cagccgaatg gcaaaataag
    51361 cgagtgtagc agaagccatc ggagctaaga aaaacggaac cgctaaatag ggattgtaga
    51421 cgattggcat cccgaaaatg attggttcat tgatattgaa taatcctggt acaagtgagg
    51481 cttttcctaa cactttcagc tgatcagatt tcgcgaggaa tgcaataaag atgatcaatc
    51541 ctaaagtcgc acctgatcca ccaacggtta cataagaact gttgaattct cctgccaacg
    51601 gataatttgc gccttgtgcg ttagctgcca tattagctaa tacgatcggg gtcaagaaag
    51661 aagtgatgat attcgctcca tggatcccta cgatccacaa tgcatggatc aagaaataaa
    51721 tcaccatgac accaagccat gtattcgtca actgcgtaac aaacccaaat gggatagcaa
    51781 tcattttgaa gatatccgtt cctagtgcaa ctaataatcc attgatgatc atcaccacaa
    51841 acgcaatgac aaatgttggg atcagagcag tgaaagaacg agaaactcct ggcggaacaa
    51901 catctggcat ttttatgacc caatttctct tgacacacat acaatacaat tcgaccgcaa
    51961 taatcgacat aataatagct gtaaagattc ctgaagttcc taaacgttcg acaaaagagc
    52021 ccatcctaat accatttact acagtttctg tctcattgat agaagcaatc aagctgattt
    52081 taccatcagt catgatcaat tcagggatac acataaagaa tgcaaaaaca gatagtaatg
    52141 cccccgtgag cggattaaca tttaattttt gttcatctcg ttcaattgac gttaattcat
    52201 aagcaaacac aatggcaaag taaatagata aaatccccat cgtcattgta ttgacgatca
    52261 tgtacaagtc actaactttg aaaaaagttg cattaaaaaa tccttctaaa aatgggaacg
    52321 gtaatggcaa aatatttaaa accaaaaaca tcgagcctac aatcgtgaaa ggaatagaag
    52381 ccatccccgc tgccatgaca gcccgaacga ttttaagttg cgcaattttc cccataggtc
    52441 ccatcaggta tttctgcaaa aaatcaaaca ttagttattc tcctttccta aatataacgc
    52501 tttttcatat tgtttaatac ggatatactg ttggtcttgg ttgagtgaaa ttttctttaa
    52561 acgatactgt ataaatgcac tggcaaaaat accgcttaca acaagaatga aaacaaataa
    52621 ctgtcctcca ttgttatttg ccataaaagg atacaagaat gtaaatcctg aggtaaacaa
    52681 cactggaatc actaataaat taaagacact ctggaacaaa aaataccact ttgtccatgg
    52741 aacgttcgtt tggtgttttc gataaagctt tacttgttct cctactgcag gcaaaatagc
    52801 taaaatcaga atcatcggta aactacttcc taaactttta gctgatagaa gcagaatcat
    52861 ccattgcatg ttcatgaaaa agaaaaaggc agtcaggtaa cgtacgatta gataacgatt
    52921 gaaatacatg tttttcaaac taagttgctt tttttctaat tcgattttcc tttttactgt
    52981 atcctgcaca atgatccttc ctttctattt atttttttga tacaaataat tcatttcctg
    53041 tgcaacttcc aataatgtca tcgtcgtcat cagatgatct tgtgcatgga ccatgataat
    53101 ttccatttct atttttgtcc cgctggcata ttctttcaga agttgagttt gtgactgatg
    53161 cgcatgaaga atctcttcat ttgcttgtcg caacttctct tctacttctt caaacatctc
    53221 tttacgcatc gagcgaaatg cttcatgtat cagtgtccgt gcatttccgc tatggaaaat
    53281 gatatcaaaa gaagtcactt gtagtgtttc actgtttatt ttttcagcca tctgttttcc
    53341 tccttattcg atcagtttga taaatttact gctgaaattc tcaaaaatag gttcagctaa
    53401 gatttcctgc tgtactttta gctggtcaac taacctaacg attgctttag tcacgaccgt
    53461 aattccttca ttttcgacat aagaaggcga aactaaaaaa acaaaatgaa tttcttgata
    53521 ttgatcccac tgcatcccag aaggaatcaa tgcaacggct acctttgttt cgattccaac
    53581 tggaacagcg ggatgtggga ctgccactgt atcactgaat atgatttgtc ccatattttc
    53641 acgttgctgg atctgctttc gcatttctct tatatatcct tcttcttcat ttatgctcag
    53701 cttttgcagc aaatcatgaa gaatttcttc ctttttcggt tcgtacgtat aagtcttgaa
    53761 aaatttttca gacaactgtt cggtgtaaat ctgctttttt tgctgtagag aaaatgctgg
    53821 tatcggtcta tctgaggaat gatagggtat agattctcca actacctttc gtattttacg
    53881 aacatcatct tcattcaaaa aaatactgac atgtaaaact ggaattttga aaaacattgt
    53941 cgaaagatca atagaagaaa taatcaggtc gattcctttt aaagttgttt cattgatctc
    54001 ataatagcct tttacactta ccactgtaat atttttaccg aattcactga ctacgcgatt
    54061 ctttaatagt tgggcactgc cgtaacccgt tgcacagata atcaatgcat gtagtttatg
    54121 cgcagctctt tctttttcca atgccgccat gagatgcaaa gccaaatagg cccattcatc
    54181 ttcattgatg gtatagtttt tcaaagccgg catgttgctg aaatgccttt ttactgcgtc
    54241 aaagactttg ggattttctt tctttatctc ctcagtcaat gggttctcaa tgcgaatacc
    54301 tcggctcaat cgaatcatca tcggtgacaa atgatcgagt agtccattga aaagctggag
    54361 atcctctact aatgaaaaat gaaattcctg agacaatctt ttcagaactt tcgctaattc
    54421 ctttgatagt tcctgatcat tttgattttc tttgtgattc gacttagcca tgagatgtaa
    54481 tgtcaaataa gcaatttctt cttcgggaaa cgatacacct gcgattacct caatacgttg
    54541 aacgatccgc tgcgccactt gatactctac tcgcttagaa acttcttgtt cgatgcctaa
    54601 ttccttgatt tcaaaccctt ctcggagccg tttgatcccc aaagccaagt gtaaagtcag
    54661 attctgtatg ataaaatccg aaacttttaa cttagcttct cttgtttcat cgagaatgat
    54721 aatgactagc tcttcaaaac tgatgtctgg gaaaaaacgg ctttgcccta aatattcttt
    54781 caatgaattt ccataatggt ttccaaaaaa agtatccatg ataaaatgcc gtcgatttct
    54841 ttcttcccct tcgatccatg tcccttgacc atgcttagaa acgattttta gtgaatatgg
    54901 aatcaatcgc tccttgattt cttgcatgtc ctttgtcaaa ctggaacgac tgatataaag
    54961 ctcttctgcc aaatcatcca taaaaagaat ggcatcttcc aaaagcaatt ggttcaatat
    55021 atacttttgt cgatcttcgg actcataaaa tccttgcggt tctctagcat atccaggtac
    55081 tatttcttgc cgactcaaaa acaagtcaaa tgtcagtctt tgtaaaatat gcagttggta
    55141 gccataacct ggtttagcaa tgatcttacc tccgtttttt tctactaact ctttgatccg
    55201 ctgcaagtaa ttacggattg tccgatcaga taataacaat tcagaagcta aacgttgact
    55261 ggtgacatac tccttcttgt gatcaatcaa atatctcaac agcaattttt ccttctgttt
    55321 cattatcatc cactcctatt ccatcatatg ttctcttcga tcacctctgc taacttctgg
    55381 atgcctgtag ggattgggac atacgcttgg aaagggatac taacaacagg ctttccaaca
    55441 gattctccta attttttgaa tttatccaaa aacatcgtcg tttgcgggct gatcagaaat
    55501 aaatcaaaat cactattctt aatcatatta tcgccttctg tagctgaaac tgcatctacg
    55561 agtacctctt ctcttttttg cttaaagaaa tccgttgtct ttgaggccat catcgaggat
    55621 gacattcctg ccgcacaaat aatcaatgct tttttcataa atcaatcact ccttttattt
    55681 ttataaacca agcatatctt gtaagcgttt tctattcaaa atatatattt ccgtagcatt
    55741 gcggaaaaaa tgtgtatcat atcttgaata ataatttctg gcaccgtgat atactagtga
    55801 tagaattttt tcaggagggg atttagtgag tatcacagtg aatattttgt atacaagtac
    55861 aaatggacaa gccagaaaat ttgcagaaga aatggtcgaa agaaacattg tcaaagcgat
    55921 tcgtgcagaa gaaggaaacg agaaatatga ctattacttt ccactagaag atccagaatc
    55981 tcttttactg atcgaccgtt ggaaagatga agaagcaatc gaaaagcatc acaaatccga
    56041 aatgatggct caaataaacg aactccgtaa aaagtataaa ttaaaaatga aagtcgaacg
    56101 tttcactgat ttaccgtaaa aagatacaca tggaatgata gcaatttatc atccatgtgt
    56161 atcttcactt tttccttatt ttttattcga tctcatctaa tgattcaaac cgtgtttttc
    56221 tcttattttt cggataagta tttcagtcac cccaatatac atgattccta aacatacccc
    56281 aaggatattc tcaaaaatgc ggatcgttac tgctcctgga accccgaata aactggcagt
    56341 gattgccaaa gcaccaaaag aattaaaaac tgttttatat ctataggtag aacaaacacc
    56401 taaagctaga ccacctaata taccgaccca gttaaaagga ataaattggc tgataccaat
    56461 aaataaaaca catccaatca atgagccaat gattcggtct actgctcgtt ctttgaaacc
    56521 aatcgacatc aatccatagc tagatacaat agaagaaaat gcaaaccctg cccacatcaa
    56581 tcgctgaaaa gggacatact ctcctgcaac gatcaaaaga ctaatgccaa atgcatagat
    56641 gagcatccaa attttttcct gcgaatacat gcctttcaaa aaaatctctt taaacaagct
    56701 tttgtctttg ttcttttctc gatgttttct gtaaaggaga actgaaaacc aacaaaaaaa
    56761 caaaaataat aagctacttg tttgtgtaaa gaaattcttg ttcaacgaat ctttaggtaa
    56821 cgaataaaca ataaagagat atgaaaagcc gtacaaagaa gcattcccca ttttgggatc
    56881 actagcggtt gccattaata tgctgcttag taaaataaaa tgaatcaaca tgcccataac
    56941 tgaccatttg atcagctgga catacggtgc tactaatagt gagaacatga cgattgctaa
    57001 acctatgatc gaatgggaaa tcttataacc aaagtcaaca aaacgaatac tcatcaacat
    57061 acagaataaa accacagcgt atggtttatg cttcgattca aataatgttg taattataat
    57121 gataaaacaa atggcaaaca atacgatgaa taatgatcgt aaaaacaatg aacaaatata
    57181 catgcacttt tcttttttag aagctgcttc tcgtattttt tgttttaaaa taaacggatc
    57241 tagttgtaga gactgataaa aatccacctg ttgtcgtcct ttctttttac ttttattttt
    57301 tacagtcatc tatgacaggt tgtaaatact atggaacatc atatggcgtt gtcattttct
    57361 tgtcaactat ttttcctatt catgttttta taaaaaaaca tatcgttttc ttgtatgatt
    57421 aaatcaccac aaaataaaca actgagagaa cgatatgctt tatgaatggt tctatcaaaa
    57481 aaattctgag atcaatagac aaaaatttga tgattacaga ggtctcttac gaaaccttac
    57541 agaagaaaaa aacattgatc gttgctgcag ttctcttccc tgctccatgt gtctgtagaa
    57601 attgtggttc tgctgtggta gatggaaata ggaaattaat ggtggtgaaa aacaagaaga
    57661 aggaaaccat tgtccacttt gaataatata atcatatgcc aatggttata cgcctaaaaa
    57721 agcagcgcta tacctgtaaa aactgtcgaa gccattggaa cgctcaaagt tattttatcc
    57781 gtccaaggca ctcgatttca aatcatgtca gacataaaat cacttcttta ctgactgaaa
    57841 aagtgtcgtt attttttatt tcgaaaagtt gttaggtatc tttgacaacc gttattcgca
    57901 cattgaaaga gttgagaagc tatttaccaa agtcttccaa aagaattctg tcttgagtgt
    57961 tgagggttgt gaatttcgtt ctcacgtttc cgttgaggat aaactgagtt ttatttccgc
    58021 ggatggcgag acagaaaaat taatcgagaa aatttaccta cacaaaaaat tcctcgatta
    58081 acaaactatt tccttagctg cactaatcct aaagaaatag aattcttagt tacagacatg
    58141 aacgccacct actttcagct caccaaacat gttctaccaa atgcgaaatt ggtgattgat
    58201 cgattacttg gtttttccac gcctttcaag gaggcgtaac ctttattcac gagttggttg
    58261 aagctttccg agacaaaaga cccgacttgt ttttctcctt attgacaaag agccattaaa
    58321 actagagaaa aaattacaac tgatcgctga ttatttgtag aaagaaaatc aaagtattac
    58381 ccaataaact tgagtcatta ggcaaaaaac actgcgaaac tcaagaatga ttttcgcagt
    58441 gtttttgtat attttttatt aactagtatt actacaaagg tttatttttc acttctcaac
    58501 gcagcacaaa attgtcttta cttatttact ggttgggttc aaccttctct actccgatac
    58561 taatatttgt ttgtataccc cttctaaaat cggtagtttc cattcaattg atgggtacta
    58621 gttgatttta aaaactatgc ttattcaatt ttttatttta gctcatatat ttcgtttctt
    58681 tctaaatttt atactgatga aaacaagtag cacacccaat attgacaata taaactggct
    58741 aatgatggtt tctccagttt ttggaagatg cttatttcca ctgcttgttg gattgtttcc
    58801 tcttatatct gagctatcag caacttttct attctctttt gttaaaaaga tcgccacttc
    58861 ttgttctttt tcgatcttga aagttactgg tgtcgcatcc aattcatacc ccgttggcgc
    58921 ttgagtttct accagctgat atgctcctgg tgctaagcca tctatcgcca gttttccatc
    58981 tgctcctgtg gttagacctg actgcagaac ggttccattg gcatcttgta actcaaaaac
    59041 agctccttgc aggacttctc cgctttggtc atcgatcttt gtcaacacga caccgcctgg
    59101 tgtaagtcga ttttctttcg tcaattctac caccgctgtc tgacttcttt cgatctcaaa
    59161 ctcgattggt gtcgtatcca attcataccc cgttggcgct tgggtttcta ccagctgata
    59221 cactcctggt gctaagccgt caatcgccag ttttccatct gctcctgtgg ttagacctga
    59281 ctgcagaacg gttccattgg catcttgtaa ctcaaaaaca gctccttgca ggacttcccc
    59341 gctttggtca tcgatctttg tcaacacgac accgcctggt gtaagtcggt ttgctttcgt
    59401 caattctacc accgctgtct gacttctttc gatctcaaac tcgatcggtg tcgcatctaa
    59461 ttcatacccc
//
LOCUS       DAFEEZ010000009        54930 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000009
VERSION     DAFEEZ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.009"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..243)
                     /locus_tag="LP245_000663"
     CDS             complement(<1..243)
                     /locus_tag="LP245_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBL1518603.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(358..936)
                     /locus_tag="LP245_000664"
     CDS             complement(358..936)
                     /locus_tag="LP245_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL1518604.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1013..1543)
                     /locus_tag="LP245_000665"
     CDS             complement(1013..1543)
                     /locus_tag="LP245_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBL1518605.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1547..2407)
                     /gene="rlmB"
                     /locus_tag="LP245_000666"
     CDS             complement(1547..2407)
                     /gene="rlmB"
                     /locus_tag="LP245_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBL1518606.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2400..2795)
                     /locus_tag="LP245_000667"
     CDS             complement(2400..2795)
                     /locus_tag="LP245_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBL1518607.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2792..4204)
                     /locus_tag="LP245_000668"
     CDS             complement(2792..4204)
                     /locus_tag="LP245_000668"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBL1518608.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4201..4737)
                     /gene="cysE"
                     /locus_tag="LP245_000669"
     CDS             complement(4201..4737)
                     /gene="cysE"
                     /locus_tag="LP245_000669"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBL1518609.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4823..5062)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(5059..6519)
                     /locus_tag="LP245_000670"
     CDS             complement(5059..6519)
                     /locus_tag="LP245_000670"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBL1518610.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6689..7846)
                     /locus_tag="LP245_000671"
     CDS             complement(6689..7846)
                     /locus_tag="LP245_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBL1518611.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7880..9250)
                     /gene="radA"
                     /locus_tag="LP245_000672"
     CDS             complement(7880..9250)
                     /gene="radA"
                     /locus_tag="LP245_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBL1518612.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9313..9840)
                     /locus_tag="LP245_000673"
     CDS             complement(9313..9840)
                     /locus_tag="LP245_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBL1518613.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            10070..10876
                     /gene="proB"
                     /locus_tag="LP245_000674"
     CDS             10070..10876
                     /gene="proB"
                     /locus_tag="LP245_000674"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBL1518614.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            10873..12120
                     /locus_tag="LP245_000675"
     CDS             10873..12120
                     /locus_tag="LP245_000675"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBL1518615.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            12196..12540
                     /locus_tag="LP245_000676"
     CDS             12196..12540
                     /locus_tag="LP245_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518616.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(12657..12983)
                     /locus_tag="LP245_000677"
     CDS             complement(12657..12983)
                     /locus_tag="LP245_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518617.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(13356..14557)
                     /locus_tag="LP245_000678"
                     /pseudo
     CDS             complement(13356..14557)
                     /locus_tag="LP245_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            14674..15189
                     /locus_tag="LP245_000679"
     CDS             14674..15189
                     /locus_tag="LP245_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1518618.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(15388..15834)
                     /locus_tag="LP245_000680"
     CDS             complement(15388..15834)
                     /locus_tag="LP245_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBL1518619.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(15881..17359)
                     /gene="msr(C)"
                     /locus_tag="LP245_000681"
     CDS             complement(15881..17359)
                     /gene="msr(C)"
                     /locus_tag="LP245_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBL1518620.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(17713..18342)
                     /locus_tag="LP245_000682"
     CDS             complement(17713..18342)
                     /locus_tag="LP245_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL1518621.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(18326..18790)
                     /locus_tag="LP245_000683"
     CDS             complement(18326..18790)
                     /locus_tag="LP245_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1518622.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(19277..20545)
                     /locus_tag="LP245_000684"
     CDS             complement(19277..20545)
                     /locus_tag="LP245_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL1518623.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(20776..21513)
                     /locus_tag="LP245_000685"
     CDS             complement(20776..21513)
                     /locus_tag="LP245_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1518624.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(21580..22149)
                     /locus_tag="LP245_000686"
     CDS             complement(21580..22149)
                     /locus_tag="LP245_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBL1518625.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            22277..23149
                     /locus_tag="LP245_000687"
     CDS             22277..23149
                     /locus_tag="LP245_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1518626.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            23491..24363
                     /locus_tag="LP245_000688"
     CDS             23491..24363
                     /locus_tag="LP245_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1518627.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            24360..26318
                     /locus_tag="LP245_000689"
     CDS             24360..26318
                     /locus_tag="LP245_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1518628.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(26569..27420)
                     /locus_tag="LP245_000690"
     CDS             complement(26569..27420)
                     /locus_tag="LP245_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1518629.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            27543..28010
                     /locus_tag="LP245_000691"
     CDS             27543..28010
                     /locus_tag="LP245_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBL1518630.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(28273..28755)
                     /locus_tag="LP245_000692"
     CDS             complement(28273..28755)
                     /locus_tag="LP245_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL1518631.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(28855..29718)
                     /locus_tag="LP245_000693"
     CDS             complement(28855..29718)
                     /locus_tag="LP245_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL1518632.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            30316..31164
                     /locus_tag="LP245_000694"
     CDS             30316..31164
                     /locus_tag="LP245_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518633.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(31335..31676)
                     /locus_tag="LP245_000695"
     CDS             complement(31335..31676)
                     /locus_tag="LP245_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HBL1518634.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            31762..32469
                     /locus_tag="LP245_000696"
     CDS             31762..32469
                     /locus_tag="LP245_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBL1518635.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            32456..32779
                     /locus_tag="LP245_000697"
     CDS             32456..32779
                     /locus_tag="LP245_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBL1518636.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(32868..33905)
                     /locus_tag="LP245_000698"
     CDS             complement(32868..33905)
                     /locus_tag="LP245_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL1518637.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(34352..35335)
                     /locus_tag="LP245_000699"
     CDS             complement(34352..35335)
                     /locus_tag="LP245_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBL1518638.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(35751..36521)
                     /locus_tag="LP245_000700"
     CDS             complement(35751..36521)
                     /locus_tag="LP245_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518639.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(36514..37449)
                     /locus_tag="LP245_000701"
     CDS             complement(36514..37449)
                     /locus_tag="LP245_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518640.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(38043..39692)
                     /locus_tag="LP245_000702"
     CDS             complement(38043..39692)
                     /locus_tag="LP245_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBL1518641.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(39887..40783)
                     /locus_tag="LP245_000703"
     CDS             complement(39887..40783)
                     /locus_tag="LP245_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1518642.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(40776..41456)
                     /locus_tag="LP245_000704"
     CDS             complement(40776..41456)
                     /locus_tag="LP245_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1518643.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(41457..42239)
                     /locus_tag="LP245_000705"
     CDS             complement(41457..42239)
                     /locus_tag="LP245_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518644.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(42232..43149)
                     /locus_tag="LP245_000706"
     CDS             complement(42232..43149)
                     /locus_tag="LP245_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1518645.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(43152..43436)
                     /locus_tag="LP245_000707"
     CDS             complement(43152..43436)
                     /locus_tag="LP245_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518646.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(44450..44857)
                     /gene="arsC"
                     /locus_tag="LP245_000708"
     CDS             complement(44450..44857)
                     /gene="arsC"
                     /locus_tag="LP245_000708"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HBL1518647.1"
                     /translation="MRKIYFLCTGNSCRSQIAEGYGKAILPTDEFEIKSAGIEQHGLN
                     PRAVQVMAEEGIDISTQTSDLIDMDYFNQADLIITLCGDAKDKCPVIPKGIKHVHWDL
                     EDPAKATGTEEEIINKFREIRDDIKSRVANLLD"
     gene            45215..45574
                     /locus_tag="LP245_000709"
     CDS             45215..45574
                     /locus_tag="LP245_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL1518648.1"
                     /translation="MKNEICEISCVHEDKVLLGKEKLQTEDISSLKSVFKILADENRL
                     KIIYALSYEDELCVCDIAATIEATVATTSHHLLSLKKNGIVVSRKVGKLVYYSIKNDK
                     FVQLLNSKLYLEDEVLV"
     gene            45571..47688
                     /gene="cadA"
                     /locus_tag="LP245_000710"
     CDS             45571..47688
                     /gene="cadA"
                     /locus_tag="LP245_000710"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBL1518649.1"
                     /translation="MSEKKQVYRVEGLSCTNCAAKFEKNVSQIPKVTDAKVNFGAGKI
                     SIEGEATIAEIEAAGAFENLKVQSEHDTEPRIETKEPFVKRNWNLLVSLFLIILALGS
                     QVVNGEDALLTEGLFILAIIIGGFSLFKEGFSDLLKLNFSMESLMTIAIIGAAIIGEW
                     TEGSIVVILFAISEALERFSMDKARQSIRSLMDIAPKEALIRRNNVEQMINVSKIEVG
                     DIMIIKPGQKIAMDGQVIKGHSSVNQAAITGESVPIEKNINDDIFAGTINEEGALEVK
                     VTKHVNDTTIAKIIHLVEEAQGERAPAQAFVDKFAKYYTPTIMVIAALIVIVPPLFFN
                     GDWNTWLYQGLSLLVVGCPCSLVISTPVSIVSAIGNSAKNGVLVKGGIYLEEIGGLKA
                     IAFDKTGTLTKGTPTVTDFTTVDSKDEEKYFSIITALESYSQHPLASAILKEADNRAI
                     SYKSVVVDEFTSITGKGIQGNIEGITYLVGSPKLFESILTDNSKIIENYQRLQQQGKT
                     AMLLGTDKQILAVIAVADELRESSKAVIEKLHDLGIEHTIMLTGDNATTAQSIGKQTG
                     VTEIKGDLMPQDKLDYIKSLKETYGKVAMVGDGINDAPALAASTVGIAMGGAGTDTAL
                     ETADVALMGDDLQKLPFIVKLSRQTLRIIKQNITFSLGIKLLALLLVVPGWLTLWIAI
                     LADMGATILVTLNGLRLMKVKSK"
     gene            complement(47909..48721)
                     /locus_tag="LP245_000711"
     CDS             complement(47909..48721)
                     /locus_tag="LP245_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1518650.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGTQENQYILEMLQKKAGKLDPKIEGLIVDELKQ
                     AGLVSEKEMDRMIEFFIINLIPPTEQDQFTYQCIDEKKQLYLGSTKFGKEAQLYLHHD
                     NQNHILHILPFTFSNFSVDRLLVYLANQESYSYFGKHLPKELVEKAILLYSINQLTVD
                     VRIAPLVYSKETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNVAYPSSK"
     gene            48883..50139
                     /locus_tag="LP245_000712"
     CDS             48883..50139
                     /locus_tag="LP245_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL1518651.1"
                     /translation="MNQVNQHDLGESIRVSREERGWTQRYLAEKVGISRSLLSKVEKG
                     TRQLSAEKLNLILDSLQEEIVPVNRVLIDYLTIHFFSNQHLKLIEAIIGMPIERFEEL
                     DYAPKGYIGQYVWNQVITIRYSIDDTVKGTVMEFSGQGCKHLAMRLKTAKSNWQEFFR
                     KVLDYQGNFTRIDFTLDDFVGSLSIPELKRKVTLGHVWTTFQVSESHGGTDIINNESN
                     GETLYLGSKKSQCRFCFYQKDYEQRKRRGISLEEAEVKNRFELRYRKEKAQSLAKIIS
                     KTHDLTKLFFELLNGAICFYDRAPNDPGAKVDAKWAAFIGNHGATTISLETIPQSFEK
                     SMNWLIHSVSPTLAFIQEVDNHFDSNLINEIISCGELSSRQQKILENLIAEPDYYQEE
                     VEFYIQCLQNMKAAKIHKKSKAQLTH"
     gene            50532..51581
                     /locus_tag="LP245_000713"
     CDS             50532..51581
                     /locus_tag="LP245_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1518652.1"
                     /translation="MPSIIKRGNSYRAQISLYNHGQHKKLTKSFSSKKEATRWALENE
                     LEKGNGKQLAERTTTFADFFENWIHIIKKNDVKETTFQNYQRTSQVVKKLFGDIQLKD
                     LNDIVVQRKIDKYAETHSRKTTHEVLLKIKTALRDAYARGYLATDFANLVKTRGKVLD
                     KRNRVLSITELKKLRTYVINHRENEFNILVLLALETGMRRGELLGIRPEDLFEYGIHV
                     RRSLSPTSEDTSLKTKNSRRDISINQEVYDILKSVPIKDNGYFFDPDGFQQSAKLARL
                     LKKLDIPKTTFHGLRDTHASFLFSQDIDIAYVSKRLGHINIQTTQNYYLELMPEKKHQ
                     QDADALNLLNSLSNL"
     gene            complement(51879..52499)
                     /locus_tag="LP245_000714"
     CDS             complement(51879..52499)
                     /locus_tag="LP245_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518653.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            complement(52580..52990)
                     /locus_tag="LP245_000715"
     CDS             complement(52580..52990)
                     /locus_tag="LP245_000715"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518654.1"
                     /translation="MVTLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNI
                     DDVKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSG
                     EKVTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            53020..54198
                     /locus_tag="LP245_000716"
                     /pseudo
     CDS             53020..54198
                     /locus_tag="LP245_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
BASE COUNT        16359 a        11265 c         9799 g        17507 t
ORIGIN      
        1 aactgcttca gttaaaaatt cgatctcaac tgtccgagta agtacatctg aatagctgta
       61 agatactcgt tcaaaagaat tttcttcagg atccaaatca acaacgaata ctgaaggata
      121 ggtttctgtt aaaacgccgc ggcgttctgt ttgacgcttt cttcctgtct gagcaaccaa
      181 catgattggg ctgccgatac gaccttctaa atctttcttg attgaagcta aagttgttgg
      241 catacagttc acctctacta tcaactatac cacatatttt taaaattttc aagtttacca
      301 taaaaaaaaa agaaatgcaa taaaaataaa taagaagctc attaagattt ttctaaatta
      361 ttcctcatta taaaatttca agtgtttttt tattttgagt tttactctcc cgtaagcgct
      421 cattacttgc ttgtgatcca ttgctaaaca ttcagccatg tctacaaaat caacgccttg
      481 catataataa tgaaaaattt tagcttctat ttttgaaaac tggatttcgc aattttcgat
      541 tgcttctttt aataaaagat gctgaatcgc taaaggttct tgcaatgtga tctctgctaa
      601 aaagtctggt ccttctgtct ctattttttg gtcgattgag acttcatctt tttgatcacg
      661 acgcttcagc gcgttctgct tcctcaacag agaatagatt tgattgctta taatgctttt
      721 ataataactt ccaaagctaa cacctttgct tttttcgtaa gttctcaatg cctgatataa
      781 agcgatcctt gcttcttgtt cccaatcctc agaaacataa tttcttaaat aataggtgtt
      841 tttcaaacgt agtaaaagtg gaaaatattt ttgatacagg gcagcaaatg cttcttcgtc
      901 accattacgt gcagcgcgca ataactcctc agacataaaa taattcctcc ataaattcgt
      961 ttatggagga atcttatcat caatgattca tcgaactgat tagaacgata tgttatttat
     1021 tttttctcat taaatcgtcc aatttttggg acaatttttt taactgctct tcattccatg
     1081 gagaattacg tcggaaatca ataaaatgca tatctttatt ttcttgggct attgtttttt
     1141 ccgttttttt tatcgtctta tataattcat aagcagaagt tcgtaatgct ccttgggaaa
     1201 agatcatcca ctgttctgct aaatcgcttg tcgccactgt cacttgtgtc aaacggtcat
     1261 tcagctgacc agcgattctc tcgatataac tgtcagccgt ttcgtcttct ttcgtaaaaa
     1321 caacatccaa ctggtatttc ttataatttt gttggatgcc cggaactagt tgggcatcga
     1381 agacaacgat gacttccatt ccttcatatt tcgcataatt tgataaacga tgtaaaagag
     1441 cttctcttgc atccgccatt ttgtcctgct ttttaagctg gacaagttcc ggccacgaac
     1501 caatcatgtt gtagccgtct acaatcaaca gctgtttttt catggtctac tccccctgac
     1561 gttgggaaaa agcctgatac ataagcaaac cagcagcaac actggcattt aagctctgga
     1621 cgtgcccggt catcgggatc gtcagcaatt catccatttc ttttttcaat cctggactca
     1681 ttcctttgcc ttcattacca atgactaaag caattgatcc tttggcattc catttttgga
     1741 agtttgtgcc ggtcatatct gtgccaaata cccaaaatcc tgtttctttg agctgttgca
     1801 cagcttgtac caaattcgtc acgcgtgcaa cagggacatg ttcgactgcc ccagtggaag
     1861 tctttgttac gataggtgtg attccaactg ctcggtgttt tggtatgatc acaccatcga
     1921 cgccacttgc gtctgctgtc cgtaaaatcg acccaaaatt gtgtggatct tcgatgctat
     1981 ccaaaatcaa aaagaagggg tcttcttttt tctcttttgt tcgttcaatc agttggtcaa
     2041 gggataaata ttcataaggt gtaatcgcaa gaacgactcc ttgatgcacg ccgtgatcgc
     2101 tcaaagtttc taatttttgt ttaggaaccc atttgactgg cacagcttgt tcacgtgcga
     2161 tttctttcag ttcttctact ttttctcctc gtgaatcttc ttgaagaaag agtttattcc
     2221 ctcgcccttg ttgtagcgct tctactgcgg catggtgccc aaagacgaaa ttatcttcta
     2281 atgcttcttc attttgatca gaaactgact gatttcgtcc agtttgcttt ttatttgaat
     2341 atctattttg ttttttgtct tcaaatccac gtttcgattg atgtttgttt gttctttctt
     2401 tacccatttt tttcaccaac tttctgaata caccagcgga tcaattcttc catccgctcg
     2461 gtttgttttg tcaaatgcag atagcccatg agcgcttcga accctgttgc gacccgatac
     2521 gtcgtaacat cagcattttt tgcgctcgta tggcttttag catttcttcc tctgcgataa
     2581 taaagttctt cttcttctgt caaaagatgt tcttccagca tttgctgaat caaaaaggct
     2641 tgtgcattcg cagaaacata attcgttgcc gcacgatgca gcttattggg ttttgtttct
     2701 ccttgatcaa tcaggtggtc acgaacatag atttcgtaaa tcgcatctcc aacataagcc
     2761 aaggctaaac cgttcaattg tgtgtaatct ctcatgcttc tcttctccat cgggttcctt
     2821 gcggtgtatc ttctaataag atcccttttt ctttcaacaa atcacgaatt tcgtcgcttc
     2881 ggacaaaatc acgattgctt cttgcttgat ttcgttcttc gatcaattgt tcaatctctt
     2941 catctaataa ctcttctgct gtaaataaaa taccgaagat cgaaagccat tgcgagaata
     3001 aagcttctcc ttgtgccaag acagcggcag aaactttcgg ctggtctaga taagtgttca
     3061 gccacttagc aagctcatag accactgtga tcccatttgc tgcattaaaa tcatcgtcca
     3121 tttcttcgat gaatcgctgt tctaaatttt ctaacaaagc gattttatcc gcatcatctg
     3181 ccaaattctc tgaggcagtt tcttggcgga atttcaaatt gtcaaacgta ttcttcagtc
     3241 gttgtaaatt ggtggctgct tctttcatcg tcgtttcact gtagcggatc ggacgacggt
     3301 attgtgtggt cgccatgaag aaacgcaaga cttgtggatc aacgtttttg atcatttcat
     3361 gtacagtgat gaaattccct agagatttac tcattttttc atcgtcttcg ccaatcgtta
     3421 catagccatt gtgcatccag taattagcga attttttccc tgttttcgct tcactttgtg
     3481 cgatttcatt ttcatgatga ggaaattcta aatcttgccc gccaccatgg atatcgatcg
     3541 tttctcctaa atgttttgtt gccataacgg aacattcaat atgccaaccg ggacgtcctt
     3601 tgccccatgg tgaatcccaa gaaatctcgc caggttttgc ttgtttccat aaagcgaaat
     3661 ctaatgggtc ttctttttgc tgctgttctt cccctgtacg ctgacttgct ccgacttcca
     3721 gttcatcgat ggattggtca cttaatttcc cataattttc aaatttacgg gtacggtaat
     3781 acacatcacc tgaagattca taagcatagc ctttttcaac caacacttga ataaatgcta
     3841 aaatatctgg catatgatcc atgactcttg gatgcagtgt agcaggctcg acattcaacg
     3901 ctttcgtatc ttcttcaaat gctcggatga aacgatcagc aacttctggt gctgtaatac
     3961 ctaattcgtt tgctgtacgg atgattttat cgtctacatc cgtgaaattc gatacgaaat
     4021 cgactttata gcctcgatat tcaaaatagc gtcgaattgt atcgaaagca atggtgctac
     4081 gagcatttcc gatatggata taattataca cagtcggtcc gcagacatac ataccgacat
     4141 gtcccttttg tatagggatg aattcttctt tttttctggt caatgtattg tagattttta
     4201 tcattctgat ctcctcactt tttctccttt gattcgaacg acttttgctg gtactcctac
     4261 cgctgtagcg tcgtctggaa catctttcaa cacaacggca cctgcaccga ttttggcgtt
     4321 ttttccgatc gttaccggtc ctaatatctg cgcattcgca gagagcatgg ctccttgttt
     4381 aacagttggg tgtcttttac ccgtttcttt tcctgtgccg cctaatgtta cgccatggaa
     4441 taaaatcaca tcgtcctcga tttctgcggt ttcgccaatg acgattccca ttccatggtc
     4501 gatgaacacg ccagttccaa tcgttgctcc tggatggatc tcaacaccag ttaggaaacg
     4561 ccagaattga gcattgatct tcgccaataa aaagagccgg tgctgatata aaaaatgaga
     4621 gaaacgatgc caaaacaagg catgaaaacc agggtatgtc aaaacgatct cagctgtcga
     4681 acgtgcagcc ggatcgtttc tctttgctgc atcaatcgct cgggtaaacc aactcatgac
     4741 tttccactcc tttcgtaaga attttatgta ggaaatcatc ttcttataaa gaaaagaagc
     4801 gccttttaaa taagtttcct tatcaaaaga cgctttccgc gtggttccac ttttcttcat
     4861 aatcaatgat tatctctgac agctaacgcc tgttatacgt tcttggctac tttgtttcct
     4921 ataaaacagt ttttcctgtt ttctgtgttt cgccaagacc actcccagag gcatttcggc
     4981 aaccattcat tgataccttg caccacccgg tatctctctt gtaatgatca gctgcttact
     5041 tttttctgtt catcgtgttt agttcagtac ttgatttaaa tgtgctaatg atttttcacg
     5101 accaagcaat tcgatcgttt caggcaattc tggaccatgc atttgtcctg atacagctac
     5161 acggattggc atgaaaagat tttttccttt tacgccagtt tctttttgaa cagctttgat
     5221 ggcagctttg acagttggag catctactac ttccatttgt tctagctgtg ctttgaatgc
     5281 gtggagaaca gtaggaactg tttcaccagc aagtacttct tttgctgctt cattcaatac
     5341 aggatgttca ttgaaaaata gcgtagacag atcaacgatt tctgcagcat agctcatttg
     5401 aggttgatac aggctaacga tcttcttcac ccattcgatt gtcttttcat ctgggttttc
     5461 tgctacacgt ccatcagcga ttagataagg cagacacatg tcagtaaatg catctagatc
     5521 cattgctttg atgtaatggt tgtttaccca ttgcagtttt ttcgcatcga aagctgcggg
     5581 tgatttactt aggcgttttg gatcgaacat tttgatcaat tcttggtgtt cgaagatttc
     5641 gtcttcgccc acaggtgacc agcccaataa tgcaataaag ttgaacattg catctggtag
     5701 atagcctaat tcgcgatatt gttcgataaa ttgcaagatt gattcgtcac gtttgcttag
     5761 ttttttacct gtttcactgt tgatgatcaa tgtcatatgt ccgaaggttg gtggtgtcca
     5821 gccaaatgct tcatagatca tcagttgttt tggtgtattg gcaatatggt catctccacg
     5881 taaaacgtga gtgattttca tcaaatgatc atcgaccgca acagcaaaat tataagttgg
     5941 cataccatcg cgtttttgta tgacaaagtc gccaccgata ttatcggatt cgaacgaaat
     6001 agcgcctttc accatatctg taaatgcgta ttctgtattg cgaggcacac ggaaacgtac
     6061 aacagattct agaccttgtg cttctttttc tgcttgttct tcaggtgtca agttcgcaca
     6121 tgttcctgcg taatgaggca tttctcctct tgcgcgttgt gcttcccgtt ctgcttctaa
     6181 ttcttcttct gtgcaatagc atttgtatgc tcgattgcta gcaagcagct gatcaatcag
     6241 cggttgatag atttctttac gttcagattg acggtaaggg ccgtattctc caggattttc
     6301 aggagattca tcccaattca ttcccaacca agcaaggttt tccaactggc ttttttcgcc
     6361 atcttcgata ttacgttttt ggtcagtatc ctcaatacga ataataaagt ctccatcatt
     6421 gtggcgggca aacaaataat tgaataatgc agttcttgca tttccaatat gcaggtgccc
     6481 agttggactt ggtgcatagc gtacgcgtac tttcgtcatt ttcttcctct tctttcaaac
     6541 tagactttga ctaacagcaa aaattccgtc agttacggct tctcaaatat catttattta
     6601 aagccactca gcacaaattt taccttttct aaggtaaata gtaaagccaa ctggttgaat
     6661 ttccttacca gttggctgaa tttctttttt attttgattg tttagtcttt ttctctgtct
     6721 cttttttatt gtcgattcct cgtcctgcat gtgcaggttt agcaaagatc atgcgtccag
     6781 cagctgtttg aagggcactt gttacaacga cttcgatacg ttcattcatg taatgctgtc
     6841 catcttctac gacaaccatc gtgccgtcat caaggtaggc tactccttgt tggcgttctg
     6901 tcccggcttt tactactaga acattcatcg tttcaccagg gatgacgact ggttttacgg
     6961 catttgccaa cgcattgata ttaagaacag gtacattttg gaattcagag actttattca
     7021 agttatagtc attggttaca atgacaccat ctaaaagctt agccaatttg atcaatttgc
     7081 tgtctacttc actgatatct tcaaagtctc catcgtacat ttcgacagat ataccctctt
     7141 ctttttgcaa ggcatttagg atatctaatc cgcgacgacc acgcacacgt ttcaaactat
     7201 cccctgagtc cgcgatgtat tgtagttcgt aaagaacaaa attagggatc atcaaggttc
     7261 cttctaagaa tccagtcttt gtaatatcat aaatccgacc gtcaatgatc acgcttgtat
     7321 ccaagatttt atatttatgg aaattttctc ctgattttcg ttctaacagt tgactctcaa
     7381 cttgactagc tgtttcttgc tcgatttttt tgcttcgtga accaaaaact ttcttccatt
     7441 cttcgattcg tgtcgttccc attctcaatc ccagatagcc taagatgatc atcagtaaaa
     7501 tcggcaatac actattgacg aatggaattt ccatattgta aagaggggtc gagatcacaa
     7561 cacctaaagt caatccgatg atcgcaccga tcgcaccgaa gagaagataa gtcaagctga
     7621 cctcacttag tttttgttct acttgtttga taatagctga gatatgtttg gccaacagca
     7681 aagataataa aaagaaaata agtgcgccta acaggctgtt ggtaaatgta ttattcagcc
     7741 atccgtttga ctgttgaccg attgcctgcc aagctgaggg taaaaatgaa atacccaagc
     7801 ttgcgccgac aatgatcatc agcaaagtaa tgacacgttt ttgcatcgtt tttcctccgt
     7861 ttcgacaatc atttattagt tagcggaaca cacgcttcaa cgtttcagcc aaagttgcta
     7921 ctccaactat ctcgattcct tttggcgctt cccagttacc taagttgttt ttaggtaggt
     7981 atacttttgt gaagccgagt ttttggactt ctttgactcg ttgttcaata tgactgacac
     8041 gtctgatttc tccagtcagt ccaatttcac cgatgaaaca ttccgttggc tgtgttcctt
     8101 tttctttata gcttgaagca atactgacag cgatagctaa atcaatcgct ggttcattta
     8161 attttacccc acctgcagct tttaagtaag catcttgatt ctgaagaagc aacccagctc
     8221 ttttttccag cactgccatg atcagagata cccgattgaa atcaagacct gttgttgttc
     8281 gtttggcatt tccgaacata gtaggtgtga ctaatgcttg gatctctacc aaaattggac
     8341 gtgtcccttc cattgccaca acgatagcag agccagttgc accgtctagg cgttcttcta
     8401 agaaaatctg tgaaggatta gcgacttctt ccaatccatg ctcatgcatt tcaaaaatcc
     8461 caatctcatt cgttgagcca aatcggtttt ttactgctcg caaaatccga aaactatgat
     8521 gttgttcacc ttcaaaatat aacaccgtat ccaccatatg ttctaacatt cttgggccgg
     8581 cgatcgagcc ttctttggta acatgaccga cgataaaaat ggctatccca tttgttttag
     8641 cgattttgag tagttctgca gtggtttctc ttacttggct gacacttcct gccacacttg
     8701 tgatgtctgg ctgcgtcatc gtttggatgg aatcaatgat aacataatca ggggagatat
     8761 gttcgatggc acgactgatt tcgttcatat ctgtttcagc gtatagataa aattctgtgt
     8821 tgatacttcc gaggcgttcc gcgcgtaatt ttatctgctc tgcgctttct tcgccggata
     8881 catataagac ttttccgcct atggctgcta attgctgaga aacttgtaac agcaaagtgg
     8941 atttcccgat acctggatcg ccaccaatca agaccataga ccctggcacc acacctccgc
     9001 ctaacacacg gttcagttct tctaattttg ttttgatccg aggttctttt ttagggacga
     9061 cgtctgcgat ttttgttggt tttgcttttt ctcctgtcaa acttgtccga gttctgcggt
     9121 ccgttgtatc ttgttcgatt tcttcgacca tcgtattcca ttttccgcaa tttgggcagc
     9181 gtcccaagaa cttaggcgac acatacccgc aattttggca aacaaattgt acttttgatt
     9241 tttttgccat tgtaccgcct ccttttatcc taatcatgag acattaaatc aagcttaagt
     9301 atctttaacg ttttatttac tggaagaacc aaatccgcct tgacgttgag cagtcgtttg
     9361 atcttgatct gcttttaaaa acggcaaaaa gatcccttgg ccgatacgct cgcctttttt
     9421 gatcactaca tccttgaaac caaagttggt gaattggaac atgatatggc cttcatttgc
     9481 ctcattattg taataatcac tgtcaatcac acctactccg tttgtcaaca ctaaaaaccg
     9541 cttcaacgga ttgcttgaac ggttagcaag ctgcaaaaat tcatcttctc ccatgtaagc
     9601 tttgattcca gtaggcacga gggttggttt caattgtttt tcattttctg atacatcttt
     9661 tttcaatcca tctgcgactg tttccaaccc ctttttccag cctgctttcc agatacttgg
     9721 aatcacgacc tcttctgctg cttcaaaatc atagccagca gcatgatgtg tagcgcgctg
     9781 cggtagattg atattttgat ctttatattt agaaataact tcaaatcctc tttttctcac
     9841 cggttttcct ccctaaataa actactccta ttctaacata tccgaggctg taaaagactt
     9901 tctttacaaa ttcttcaaga aattctgcta tcttaaagta aaccattaat tcgttctttt
     9961 tccaaacgac tgcaagttgt acaaaaaaac tattttttac atgactttac tcgtcaaaac
    10021 aagtagaata gaacgaaatt aatgagtgga tatttgattg aggtgtcaca tgcgtaaaga
    10081 aattaaaaat gcaaaacgaa ttattgtcaa agtaggaaca agtacattga tttatcccaa
    10141 tggaaatatc aatcttgcgg caatcgatca gttagctttt gtcctttctg atcttagaaa
    10201 tcggggaaag gaagtgatct tagtctcatc aggagctgta ggcgttggta tgcataaatt
    10261 acatttgtca gaacgtccga ctttgattcc tgaacagcaa gctgcggcgg ctgttggtca
    10321 agccgaactg atgaatatct ataatcaaag attcagtgta tataatcaac agacggcaca
    10381 gatcctcgtg acaagagacg tggtagatta tcctgaaagt cgtaaaaatg tgaggaatac
    10441 attggaacag cttttgatta tggacacgat ccctatcgtg aacgaaaacg atactgtagc
    10501 agtggatgaa ttagatcatc tgacaaaatt tggcgataat gatcagctgt cagccatcat
    10561 ggcaaaactt gtcgcggcag accttttgat cgtcctttct gatatcgacg ggttttattc
    10621 agataatccg actacaaatc ccgaggctca gatgtatcgc tatatcgata aaatcgatga
    10681 aaagattctg gcacaagcag gtggtgctgg tagcacattt ggaacaggcg gtatgcagag
    10741 taaattaaaa gccgcttcta ggatatttga agcaaacagc gcaatgattt tagcaaatgg
    10801 aaaaaatccg gcaattattt ttgatattct tgcaggaaaa gaagtaggta ctttatttaa
    10861 ggaggacttg aaatgactga cttgatgcaa ttaggacaac aggcaaaaga tagcgcgcaa
    10921 caactagcac ttatgcctac aaaccgcaaa aatgagctac ttgttcaaat ggcacaaacc
    10981 atcaaaaaga atcaacaagc gatcattgaa gcaaatcata aagacttaga aaaagcagtc
    11041 gaaaacaata tcagtgaaac gatgcaagac cgcttgcagc tgacacctga gcgaatcaat
    11101 gccatggcta cagagatcga aaaaattgct tcgttagacg atcctattgg aaaagtagat
    11161 gagatgtgga cgaacaccga cggattgaga atcggcaaaa agcgcgtgcc actaggcgtg
    11221 accggcatca tttacgaatc tcgtccaaat gtcacgacag atgcagctag tctagcattc
    11281 aaatcaggga atgccgttat ccttcgcggt ggcaaagaag cattcttctc gaatcaatta
    11341 ttagtccaat tattgcagca agtactggtc agtgctggcg aatctcctta tgccatccag
    11401 tttgtcgatg atacttctca tgaaactgca ggacagttga tgcgattgac agaatactta
    11461 gatgtgctga ttcctcgagg cggagcaaaa ttaatccaac gagtcaaaga acaggcaacg
    11521 gtacctatca ttgaaacagg tacaggaaat aatcacgtat atatcgataa agaagcacag
    11581 ttatctatgg cagtgaacat catcgtcaat gcaaaagctt cccgtccatc tgtctgtaac
    11641 gcggcagaaa cattgctgat ccattctgag atcgcacctt ttttcttgcc agctattgaa
    11701 aaagaactgg tagaacacgg ggtctcttta cgtgcggatg ctcgtgcgtt agaatatcta
    11761 gagacggctg ctttagcaga agacacagat tgggatactg aatatctaga ttatatcctt
    11821 gctgtcaaag tggtcgattc tttggatgaa gcaattgcac atatcaatcg gcataatact
    11881 aaacattcag aaacgatcgt gacagatagt tatgcggcta gtcaacgttt cttaaatgaa
    11941 gtggacgcgg cggctgtcta tgtcaatgcc tccactcgtt ttacagacgg atcggtattt
    12001 ggttttggtg cagagattgg tatctctact caaaagttgc atgcccgtgg tccaatgggg
    12061 ttaaatgaat taacttccac aaaatatatc atttatggcg atggacaaat ccgcgaataa
    12121 tgtttcgtgt gaaacattat tcccgccttt tgcctttttt ctgtaaaggt tctatccaac
    12181 tagaaaggtg tcaatatgtt tgaaatttta atgatttttt ttatttacct tatttctctg
    12241 aatatcgctg cttttctggg agtcggtatt ttatcccttt tctttcaatt caaaaaacga
    12301 agcataggga gtcaacggga aaaatggtcg cagtattttg acaaaatcgg gcaaaaaggg
    12361 ctggttacac gcttgcacat tagttacatg gttgcattat gcttattagc gacaatcaat
    12421 tactattctt ttttcgatca ttcaatcgct tatacgatta cgctactgat tgctgggatt
    12481 tttcacttat cttataaata tcagctgaat aaaaaccact tgaatcggac tttccgctaa
    12541 aaaatatccg tacgataagt agagtgcctt gaagatcggc aaaaaactgc cggacttttt
    12601 agaggctgtg acaaagattt tgtcacagcc tctttttcca tataaacggc gttcgcctac
    12661 cagctgcctg gtaaatctgt ttcctcttcg ttaagaagcg aaaatccgtc aaatgtttcg
    12721 ccatcataat aacgaagcag ctcatccatg gacaagttca tcgttttttc tttttcttct
    12781 tccgctgatt cagccagtag ctgttcccga tacacctgat acataccagc tattttttgc
    12841 tgcatcgctt ttctagtttc accttccgca ttgattattg gcaattcttt gatatagcca
    12901 cgataaatca accgatcatc tgaaaattca atgggtaatt caacgagtgt caacccgact
    12961 tcctgaaaat attcttccag catctattat ccccccattc tttttcttaa atgaatttta
    13021 gcttacctac tgaaaatttt ccagtttcat tattttgaga aaaaaaggga atgtgacaaa
    13081 aatcgtgtca catccccttt ttccgaataa atggtgttct tctgccaact cctcaatcat
    13141 aagtcacaat attcaacaaa catgagaaac tgttttttga aattgttcct tgtgattcag
    13201 agttaaacga cagtctcaca acctcttggt aaacggcgtt caaaagcttg catctgcggt
    13261 aataagccca accaaacgaa aaatatgaga agctattttt gtttggctgt tcttatgact
    13321 tgatgcagga cagctttttc acaacctctg atttcttatt cttcttcatt tgtagcaaaa
    13381 taattacggt gataaatgat acaacataca ctgataagaa caatggcacc tgcaaaataa
    13441 aacgcatagc tttcaccaat atgttcacca atcacacctg caataaatgg tgctaaagct
    13501 ccaccgaaaa agcggacaaa actatagctg gacgaagcaa cgtttcgttg cagacctggt
    13561 atttccatag caatcgtcgt caacagtgta ttgataattc cttggaaaaa tcctgctaac
    13621 acaatgctga tcggtacaag gactggcata gaagttccag ctcctaataa cagcaaacaa
    13681 ataatgaata agacaaatgc tgctaaaatt gtccgataag tcgtaaactt ccgctcaaga
    13741 gccggtgcaa cgaaaatcga agcaatagcc agaagcacac cccagccaaa aaatacaaaa
    13801 ccgacttcta attcagaata gccaatcaat aaaaatggcg catacgcaag taaagtaaag
    13861 aatccgaaat tatataacaa tgcgattagt ccaactgaac gaagtttatg attgcttaac
    13921 gctttgacac cttcccaaag gcctactttt ctctttggtt tctcagtttc aggtaaaagt
    13981 accgctaggg ctataaaacc gcaaaacatc aaaaatgcta ccccaaaaaa tggataacgc
    14041 catgaaccac tgcccaagac cccaccgact agagggccaa cagccattcc gcagccaagt
    14101 gctgcttcat acatcatgat tgctttttct gtgttaccaa ctaaaatact gacgatcgtt
    14161 gctaaagcag tagagacaaa taaagcattc ccgacacccc agccggcacg taacccaatc
    14221 agcattccga tattcccaga taatccgcca agaccagcga atacaacgat gataaacaat
    14281 cctgtcatca atgttttttc aaaccgatcc gactagataa gaaacctgta aatagcatca
    14341 ccacaccagt gactaacatg taactagtaa ataacagggt cgtttcagct ggcgtagcgt
    14401 ttaactgtgc agcaatcgtt tttaagattg ggtctactag acccactccc ataaaagcga
    14461 tcatacaggt agctgctaca actagcgctg aacttttccc ctttgtttct tcatttgttt
    14521 gttcttgtat atctatttga ttctccaata tttccatccc tttctctcta ttagcatcat
    14581 acatgattta ttttacatgt aaatatgcac atgtaaaacg tggaaacttt actgtgatat
    14641 aataaagaaa ataagacgag aggtaggatt tttatgaata ctttagccta tatattatta
    14701 tgcgtgcttt tatccaaacc acgttctggg tatgaattga agcagctgat cacaattttt
    14761 tgggaagccc atcacagtca gatctataca acgcttgcca agttagacca gcagggttat
    14821 gtgaccgttt tggacaaaga cgagcactct caaaaaaaga tctaccactt gactgatgaa
    14881 ggacgtgctc ttgtagagga atggatcaaa gaggaaactc ccgctcctac gcaaaaagat
    14941 gaatttctag caaaaatcta tgctttttcg acgctcgata aaacaacagc tactggactg
    15001 ctattcacta gagaacaaca gctgaacaaa atcatgcaaa aaaatcaaaa aaaattgaat
    15061 gacctctcgc tagacaagaa acaagaattt ggacgttatg ttgtgatcca gcgcagaatt
    15121 atgctttgtc agcaggaact ccaatggtgt cagcaagtaa gagaacaaat gcagcagttt
    15181 tttgagtaag ggataaacag aacctttcta gaaatatcta ttgaagagca aattatcttc
    15241 aataaaagag caatacagtt ggaaaagaaa aagcgatccg aacgacaggc caaaacctat
    15301 cgttcggatc actatttttc tagaactgca ttcaagagac tatgacaaaa agcatgccaa
    15361 ggcctttttt caaataacag tgttccatca ttcattactt tgaattgctt ttagcacact
    15421 tcttgaaagc gggccaacga tgatcaactg caacggtaaa gcggcaatca cattcatttt
    15481 ccaagcattc atataagcag agaataattg atcaggtatt ccttgttcca tgatcacacc
    15541 gaataaagac atacatgtca ccattcctaa aaccatcaag catgaaatag ttaagatcat
    15601 ttggaccttg ctttctggat ttactggtag tttaaaggca atttttttcg ccagcacacc
    15661 gatgatgaag acatccaaaa tgaaagccac cacgaatcca ggcactagac caatcaacaa
    15721 acttgataaa tgaagatctt gatgcagcca taaattatac gcgctcatcc ccaagaccat
    15781 caaaaaacac atcattgttg taaaaattat tccttctttt ttatttgtag gcaatctgta
    15841 ccactccttt aaatttgtca cgaaaatcat cgtagcacat ttaaaaattt ctcgtaagta
    15901 ctttttttat tttctgccct tttatttcat aaacttcatc agccgtacgc tcgacaaagt
    15961 aagaatcatg agaagtaaac aaaatcgttc ccggatatat ttgcattagc ttctctaaag
    16021 cttcgatcgt tgccatatca ataaaattag tcggttcatc taacagcaac acattacttg
    16081 gcttagtaaa aagcaaagca atcgtcagac gggtcgcttc tcccccactt aatgtacata
    16141 acggtttcgt caaagtttcc tgagcaaacc ctaagtgatt cagcaaacta cggacaagcg
    16201 attctgaaaa ctctgtttgt ctcatgacaa aacgaatgat ggattcttca gatgtcattt
    16261 gataaccctt ttgctgatat acttgaaagc ttactttcgg agagagaagg attccttctc
    16321 cttgtttgcg gatatgttct aataaggttg tcttacctga accattttca ccgacaatcg
    16381 cgattttttt acctaaagaa aactgaaaat caccatttac cagtaatgtt ctcccacttc
    16441 tttccaattg gacattttgt cccatgatgg gatagcggct gtggagttca agagattttg
    16501 gtactggaaa acggatttgt ttcatctgct gcggcttggt tgtttctcct attttttgga
    16561 gtcttctctc taatgttttc gcattctttt ggatggcttt ttgtacactg tctttttgtt
    16621 tagaggaaga caaccgatcc ggtctgattt gttgcttttt ctttttactg gacacttttt
    16681 ccaacttttc cgcttgtttt ttcttttctt ggatcgattt ttccaatcgt tttttctctt
    16741 tcatgatcga ctctgcttct cgtagctgag tctttttctc caattccttt tgagtgagat
    16801 aggcactata attccccgaa aactctcgga tttctccgtc ttttacttcc cagattttcg
    16861 atgctagctc atctagaaaa tagcgatcat gactaacaaa aaccagcgta ccataataat
    16921 aacgaagctc ttcaatcagt cgatcaatac tttttctatc tagatgggtt gttggctcgt
    16981 ctagaagcat cccttgttca taagaagaaa gaagacgtat caactcgatc tttcgttctt
    17041 cccctccgct ccatttccgc tctgaagttt cttccagtct taactggaaa tgactggcta
    17101 attccaaatt taggtccttt gcttcagcga gataggttaa ttgaggcagg tagttgaagg
    17161 tgatctctgt ttggattttc ccatgatcgg gaaaaagttc accggctatt agtttgagca
    17221 aagtcgattt accgacacca ttttctccta tgatccctat acgatcttgc tgatagacac
    17281 gaagagaatc aatagatagt tctagctggt tgccaaagct gacttgtaga tttgttatat
    17341 ttactgctaa attttccata tgttttacac tcctatttca tgtaaaacaa caattatcga
    17401 tactaaaaaa gagcagaaaa atctgtttgc aaaaaaactg catcacatct tttcctactc
    17461 tgaacgaaat aactatgact aaatcaccaa atctgtcata gctttcacct attctactgt
    17521 cgttcgaaaa aatggacata ctccatccat gaaattgttg tttatacatg tcttttgaat
    17581 ttatttagtt gttattcaaa agttcgaaac gtaatttcat cgatgcagtc atttttccga
    17641 cctccttttt tattaggtta ccacacacga ttcaaaaaaa gcaatagcta ctgaatagta
    17701 actgaaaacc ttttattcga acgtagtgat cttttctggt gctaaacgaa cagactcgta
    17761 accttcttct accgcttttc ctattgataa aataataact ggaacataac ggtctttatc
    17821 caaaccaaat gcctctgcca actgatctgc ttcgaatcca ccaattggat ttgtttcata
    17881 gccatgatca cgcgcaacta acatgaattg catagccgct aagctagaat cgactttgac
    17941 tacatcgttc atttcttctc ttgaaaaact cttgtaataa ggaatgatcg cagctaattg
    18001 ttgatctctg acttcttttg gcatcttccc tgattcgtaa gcttggttat agatttcttc
    18061 gccatattcg taacattgca tatcgccaaa aatcatgacc attgcagaag aagtatcatt
    18121 ttgtctcgta ttgaaacgga tcaaaggacg caagatttct tttgcttcct cgctttcagc
    18181 gaccacaaag cgccatggtt gcatattgac agaagaaggt gcagtcgtcg cttctttgat
    18241 catttccagc atttcttcgt gtgggatttt gtatgtttca tcatatacgc gaacggatct
    18301 tctaccagtc ataattgttg aaaaatcatt tttttgttcc attattatta acctctttcg
    18361 tttctgttgt tatattgcaa agttgggtat tcaatttatc taaaagtgtt agaaattgtt
    18421 tcatttctac atcgctgaaa gccggggata gcacggaacc tgtatcttta tggtccattt
    18481 cacaatgctc gattttcttc tgggcttttt ctgttagcgc tacatacact tcccggttgt
    18541 tctgaggatt tctctgacgc gaaacatagc catttgcttc caataccttc agatgacgag
    18601 taactgctcc ttgatcaatc tgcaactttt cttgcaaact gctttgtagc aatggatttt
    18661 cttctttcag tctcatcatg atctcgtatc tagtaagact tataccgata ttttcttcaa
    18721 agatctggac gattttttga tcggctaatt tgatttgata taaaaggtga ctaatctctt
    18781 ctaaagacat aatttcctcc tttctaataa ttgactcgtc aacgattgac ttgtcaataa
    18841 tagaataaaa aaagaaaaaa gtcaaagaat cagctgtgta ataaaaaaaa cgctctcaat
    18901 agaaaagtat agagaaaaga aattttttgt agaatgaacg gaaaaaatga taaagaaagc
    18961 acaacgctaa aaccaagatt attgattctt atcaaactat agaagatagc tcttctgcag
    19021 tagaaaattt tacaccgcca aaaatttccg aaatcgcctt ttgcaagaat cccgtcgaat
    19081 attagaaatt ggatcagtat gcttaaacag taataaaaaa gttatgacaa gatgttgtca
    19141 caaccttttt tgagtaaacg gtgttcaaaa acttgcatct gcggtaataa gttcaaccaa
    19201 acaaaaaaca tgaaaatctg tttttgtttg gctgttctta ctacttgatg cagggcagct
    19261 ttttcactac ctctttttaa taaccataaa atcctattcc ttcatatctc cagcccatcg
    19321 gtgttagcca atctctttcc ttagcactca aggtatagtg atgggtacca gttttttcat
    19381 ttggattaaa tagtcgataa attggcttgg aaccaccaga ataaaaactt agaccttcat
    19441 aacgccaacc gatttttgtt aaagagttga tctcagattg tgccattgtg taatgatggt
    19501 ctccactgta aggattgtat aaacggtaga caggttgtcc gctgtttggt gcttgccaag
    19561 caatcccttc atattcccag cctacagttg gcagataatt tttttctccg gcattcaatg
    19621 tatataaatg ttctcctgta tgacggttat acagacgata catcggagaa gttgaagttg
    19681 gtgctgtatc atactgtgtc agattatagg tttcgattac attgttcaat gtagaaccat
    19741 aattaggcgc agtggcataa cgacctgtta gccaagccgt agcatctttg taagagttcg
    19801 tattgctttt ccatgcaccg gaatagtagt aaacgcctgg ctgaaaagaa gtcgtcttca
    19861 ataccgttac gttatcttgc aatgattctt tgtacgaagg atattttcta aaagcggcat
    19921 tcaccgtaat ccattgccca ttcacatatt ccgaagtagg catcgtaaca gattggccat
    19981 tatagcttcc tttaatccca aatagattgt aattaggggc agaagccaaa gtactgttcc
    20041 cccagccact ttcaacgatg gcttgagcaa tcatgactga tgcatataag tcattggcac
    20101 ttgccaaact ttgtgcagtt gaggcaatac tatcaatgaa cgcttgttga gaattagcag
    20161 atgagcgagc ataaaaagca tagccagtat agttttcgaa ttcagacaaa tctgcttgat
    20221 gggtatgtgt caatgtttgc ccatctgtca attggttcgt gatttcttct gcattctctg
    20281 gattgttctg agcttctgct gatgtactgt cttcggtttg tgtttgttct gttgtttcag
    20341 ttgttggttc ttcggttgaa attgtatttt ctgagacagt agctgactgc aaagtactct
    20401 ctgtatcgtt ttcaattcct gtttctgaag aactcgatgt ctgagttgcg acagtttctg
    20461 tcgattcttc agctagcact gttgtgttgg caactgctag atttcctaaa agaataacgc
    20521 taaataataa attctttgct ttcatctttt ttctcctttg aattatgaaa cttttcctaa
    20581 ataacagtgt aactaaaaaa gtaaaagcaa gtcaatgtcc atatttaaat aacatttgtt
    20641 tctttttgat aaatttgctt tttctacata aaaagacgta aatgaagaat attcttctcc
    20701 attcacgcct taaattgatg gtcgtttgaa taactattta acaagtaatt ctctttggat
    20761 attatccgtt atggattata cttcctgtgt cgtcggacgg ataatcatgt tactgacaga
    20821 catccggtct ggcgtttcta tcgcaaatgc tacagcagaa gctatatctt cggaggtcaa
    20881 tccccattct ttttgcgctt catgaagttc aagagcagcc tttttgtcgc tgatggtttg
    20941 atataattca gtttgaacag ctcctggaga gatgatcgta gatttgatgt tattttgccg
    21001 ttgctcttga cgtaatcctt ccatgattgc acggacagca aattttgttc cgcaataaac
    21061 ggcggaatca ggataaacaa catgtcccgc cacagaatca gttgaaatga tatgcccaga
    21121 tttttgtttt tccatgattg gaagtacggc ggaaattcca tttaacacac ccatgatgtt
    21181 gatatcaagc atattttgcc attcatcacg gtgaccttca actaatggag cggttggcat
    21241 gattcctgca ttattgtaca atacatcgat tcgaccgaac ttttccatcg ctaaatcgat
    21301 aactgcttgg acttgtgcaa aatctcttac atctgctgtt tgaatatata gctcagcttc
    21361 tggtaaagat tcttttattg cttttaggcg atcttctcgg cgtgcagcta taactagttt
    21421 agcccctttt tctgctaata gcttcgttgt tgcttcaccg attccgcttg aagcgcccat
    21481 gatgacaatc actttttctg ataaatcatt cattctattc tcctcctgtt ttgaaaaatc
    21541 tcttgcttat actcactatc tcttatttca tcttactgtt caaataatcc gttcgacagg
    21601 tttgacgatt ttggcaggga ttcctgcaac gatggtattg tctgggacat ctttcgtaac
    21661 agttgcattc gctgcaacaa tggcattctc gccaatcgtt acgcctggca gaatagttgc
    21721 tcctgctccg atccaagcat ttttcttgat gtggattggc tttactgaca agcctcttcg
    21781 ttcttttgga tcggttagat ggttcaccgt gatgaggttg acacgaggac caatcaatac
    21841 tgaatcttct aaacagatgc cacctaagtc aacgaacatc acttgacgat tgataaagac
    21901 atttttccct atactaatat gtttgccgaa atctgtataa aaaggcagca gaacagtcac
    21961 cgtatcatct actttgtcac taatgatatt ttctagccgt ttgcggatat ctgctggttc
    22021 atggtaccca gtattcagcg ctgctaaagg ctcttcgttt tcagcttgga tctgatggat
    22081 cacttcaaag agcggatccg ttactcgaat ctctttattg acgatttgtt tttcgatgag
    22141 gcttgtcatt ttgctccctc cttttatcct tactttataa cggacggctt atcatgtcta
    22201 atacttataa aacatactta actattcctt ttaactatac ttagtggtat gcttttttaa
    22261 aaacaggagg gaaaaaatgg atattcgtat actgacgtat tttttagcag tagctagaga
    22321 aaaaaatatc agccgagcag caaaatctct gcatatcacg caacctactc tctcaaaaca
    22381 actgaaagat ttagaagaag aacttggtgt gacacttttc actcggggct cccgagagat
    22441 acagttgacg gattctggtc gatatcttta ttcaaaagga aaagaaatct tgtcgttggt
    22501 agaaaaaacg gcgaacaatt taacaaatga cgcaatcatc tctggagaaa tctacattgg
    22561 cggaggcgaa actaaagcaa tctctttcat ttctgatagc cttcattcgt tgatcaaggc
    22621 gcatcctgat atccagtttc atttatatag cgggaatgca gatgatatca tagacaaact
    22681 ggatagcgga ttacttgatt ttggactcgt aatcgaaccg acaaacaaac aaaaatacca
    22741 gtcatttcga ctgccagccc aagatcgttg gggacttttg atacatcgaa atcatccttt
    22801 agcaaagcaa accgtcatcc atccgcagga actgaaaact gttcctttga tcatttcccg
    22861 gcaaacgtca gtggacagtc aactagctga atggctaggt ttcagcatag atcagttatc
    22921 gatcgtcgga acatataact tattgtacaa tgcttctttg atggtcgata acgggacttt
    22981 tggtgcatta gctctagatg ggatcatcaa tacttatggg acggaaaaaa tattcatccc
    23041 actcgatccg ccattacaag cttcactgaa tctcatttgg aaaaaagacc agcctctttc
    23101 tcctgctgct cgtaaatttt tagatgtcct aacggagaaa tacagttaag tagagttttt
    23161 ttccttcgct ttcagctttt taacaacgaa taagataagc aaaagatcca acgattaaat
    23221 aacataagtt tcttaattta tttcttcctt ttatttctga taattccagt aaattactat
    23281 aattataaaa aaagaattga caaaacataa ctgtctatat aaaattgatt acgttaacaa
    23341 taattcgttt catgtgacta gatcatacta ggcatgaaaa atctctgagg aacatggttt
    23401 ccctaggagg tttttcgtgt ctatttttgt ttggccgcaa tcaactggtc tagcaaacgt
    23461 gaaaaccaaa tcttcaaaaa gggtgcgcgc atgaaaatca aaaagatctt taatcaaaat
    23521 gcagtattgg tagatgacgg tggacaggaa aaagtagcta ttggaaaagg gattggattt
    23581 gacagaaaaa gaaatgattt gatttttgat cgtgatgtcg aacggatatt tgtcatggaa
    23641 ccagaaggtc aaatcaagtt gcaaaattta cttaatcaga ttgatgaacg ctttttattt
    23701 gcagcagaaa cgatcattga tcatgcggaa actgttttga tggaaaagtt gaatgaacat
    23761 gtattgatcg ctttgaccga ccacattgct ttttctgcgg agaacattaa taacggtatc
    23821 gtcatccgca acaaactttt aagagaaatc gaagtgcttt acagtgatga attcagtatt
    23881 gctcaatggg cagtagagta tctgacaaaa gagcttggga ttccatatac ttatgacgaa
    23941 gcaggatata tcgcaatcca tattcacagc ggacgaagcg gtcggaacaa taaccatcgc
    24001 agtatccgtg aagtgacgat tgtatctgac atcatccatt tagtggaatc agaattggaa
    24061 acagatatcc attcagaacc attttcactg aattattcaa gactggtgaa tcatttacga
    24121 ctgcttctac aacgaaccca tgcgcaacaa tatgctgttt tagacacgga aatcgtagaa
    24181 atggtcaaac gaaaataccc agaaagctat aagatttcta aaaaaatccg tgtgttgctg
    24241 accaaagaat accagctcgc gatcacgaaa gaagaactgg gttacttggc catccatatc
    24301 gagcgtttaa gaagcgcaat cgtacaaaca aatgttaaca atcatgagga ggaaaaaaat
    24361 tgaaagcata tctacaacga atgggacgtt cccttcaact tccagttgcg gtcttacctg
    24421 ctgctgcttt actagtaggg atcggaaact ggtgggcatc ttatagtaac gacattgtcg
    24481 ctcatttttt acaagctggc ggtaacgcag ttttaggtca attacctttg ctgtttgccg
    24541 ttgggttagc actagggatg tcagtggaca aatcaggtgc tgctgccttg gcaggtttgg
    24601 tcgcatttga agttccagta aatgttttaa aaactgattc agtagctact ttattgaata
    24661 tcaaaccaga atcagttgat ccatcttttg ctcagatcag taacgtattt attggtatta
    24721 ttgccggatt gattgcggca gctctttata atcgtttcca cgaagcaaaa ttaccgatgg
    24781 ctttatcttt ctttagcggc aagcgtctag tgccaatctt ggctgccttt gtcatgttgc
    24841 tgatcagtgc agtgctactg ctcgtatggc ctccggttta ctctgcttta gtttcttttg
    24901 ctaaattcat tttgagttta ggctggggtg gtgcaggtct ttatggcttc ttcaaccgtt
    24961 tactgatccc tacaggattg catcaagcaa tgaactccgt gttctggttt gacgtagcag
    25021 gaatcaatga tattggtaaa tttttggctt ctgaaggaac aaaaggcgta acaggaatgt
    25081 atcaagctgg atttttccca atcatgatgt tcgggcttcc agcaggagca tatgctattt
    25141 acagaaatgc acgtccagaa aacaaagcaa aaacagcttc cttgatgcta gcagcagctt
    25201 ttgcttcatt ctttactggt gtgacagaac cacttgaatt ttcatttatg ttcgttgctt
    25261 ggccattata tgtcttgcat gcaattttca ctgggatttc tttagcagtg agtgcattct
    25321 tccattggac agcaggattt gcctttagtg ccggatttgt cgattacttc ctatctttga
    25381 aaaatccgat tgcgaatcag ccattgatgt tgatcgtcca aggattagta acagcagtga
    25441 tttactactt tggctttaac tttgctatca aaaaattcca tctgatgact cctggccgcg
    25501 aggaagcaga tctttcagat gacgatactg caacgactaa ttcagacaat aaatatgcgg
    25561 cacaagcaag caaaatctac gctgcattag gcggagccga caatgtaact tcgatcgata
    25621 actgtactac acgccttcgt ttgcaagtca aagatacagg cctgatcgat caaaataaaa
    25681 tcaaagccac tggcgtacct ggtatgaaga tcatcgacgg aaaaaatgcg caagtcatcg
    25741 taggtacaga agtacaattc gttgcagatg agatggcaaa actacatggt ggtgctgcag
    25801 cacgacctgc acaaacaaac accgtggtta aaacagaaac atttgccggt gaaacgatcg
    25861 aacaagatat ttacgctatc gcaaatggga aactgattcc aatcactgaa gtttcagatg
    25921 atgtattcgc ggaaaaaatg atgggtgacg gctatgctgt attaccagaa aatggagaaa
    25981 tcttctctcc aatcgctggt acgatcacaa acattttccc aacgaaacat gctgtcggaa
    26041 tccaaacaga tgctggtatc gaagtcttgc ttcatatggg catcaacact gttgacttaa
    26101 aaggcgaacc attcacttta tatgtagaag aaggtcaaaa agtcgcaaga ggtcaattga
    26161 ttgctttagt tgatcttgcc gctattcaat ctgcaggcaa aaacacggat atggtcgttg
    26221 tattcacaaa tggcgacaaa gtccaaagct tagaaatcga acccgcacgt gatgtaaaag
    26281 caaatgataa aatcggctct gtttccaaca aagcctgagc catcgtcttc cccagacttt
    26341 tttatcgata aacaaacagg agctgagaca aaaatcttgt ctcagctcct ttttccgaat
    26401 aaaaacggcg ttctcctgcc aactccgcgg taataagtcc agctaaacga aacatatgaa
    26461 gagctatttt ttatttgact cttcttatta cttgatgcag aacagctttt tcacaaaatt
    26521 tttcttcata ctcaaaacta atcggctttt tcacaacctc tttatacatt attcctgatc
    26581 caatatttct tttaatgctg cttcaagaga agttaatggt tttcccaata ctttttctaa
    26641 atcatcagag gaaatagcta actgatcctt tttaatatca tgttggatcg ctaaaaacat
    26701 gtcagctgct tcttgaggga atccggcttc ttttagattt tcgacaaacg ctgcatcact
    26761 tgcttcaata atttctaact ctttacctgt cgcacgctct aatgccttgg ctaattcttc
    26821 atagtcagtt agattgccgg ataattctaa gatttctgga gagtcacttt ctactagtac
    26881 ttttgctgca gcttctgcat attcacgttt caatgcccaa cctgtttttc catttcctgc
    26941 agcataaacg aattgaccag tttttaaagc ctgcccaatg ataggtaatt cattctctac
    27001 ataccaatta ttccgtaaaa atgtatggga aatacctgaa tccttaatca ttttttcagt
    27061 gaattggtga tctggcgcta atacactgat cgagtgatcg gcatctgcaa aacttgtata
    27121 agcgatataa gataccccag ctgcttgtgc tgccttcact acattcttat gttcggcttg
    27181 acgatttcct ggaacgccag agacaaaaag caatcgatct attcctttca acgcttcttt
    27241 cattgagtct aaatcatcat aatcaccaat acgtatatta aatccagctt ctttcagtgc
    27301 ttctcctttt tcttcactac gtactagtac atagatttca ttttgtggaa ccatcttttt
    27361 taagaattcc agcgcataac caccaaaacc tccagttgct cctgttacta aataatgcat
    27421 atttgccact ccctattctt tttatttgtt aagatttaca gctgtacatt tataaattac
    27481 acctttatca taaagagtgt ggtaagataa gtcaagcaaa aaaaatgaaa ggatgacaac
    27541 tgatgaagta ttctctgcaa tttagtgatg caatccatgt acttgcctat attgaaatgt
    27601 ttcaagatac ccgatcactt tctagtgaga tgattgccag tagtatcgaa acaaatgcag
    27661 caaatgtacg taaaatcatg agtcagctca aaaaatccgg tttgatcttt acaaaaaccg
    27721 gaaaaccgca gccttccctt gccaaaagtc cagatcagat ttctttacta gatgtctatc
    27781 gcagcatcga aggtaataca cagcttatcc aagtcgatcc aaaaacaaat ccaaattgcg
    27841 tcgttggtgc gaatatccaa gaagctttag aagaaagcta cgctcggctg cagaaaaagg
    27901 cagaagaaga aatggctaag atcacacttg atagtctgat acataaaata gccgttttgg
    27961 aaaaagaaaa aagaccagaa aacacaggcc tcgtagagag atttttataa ttctctctac
    28021 tgtgcctgca tttttctgat cggaatcgtc tacataaatt cttttattct ccgggggaca
    28081 aaagccttgt catgcccctt tttcctctct aatgctcagg tcaaagcgct gaagtcatga
    28141 cgtcttgata aacggtgttc aagtagctga ccctcggcat tagttctgaa aaatgcaaaa
    28201 tatggaaagc tatttcccat ttttcctctc taatgctcag gtcaaagcgc tactttcacg
    28261 acctctatat tatcatggtt tattgactac cggtatccag atttctccca tatatttccc
    28321 gttggtaact cccatttcga ctacagcatt tggaccccca acataggcgt aatcttctac
    28381 ttctcttaaa acatgcccaa aggccgtatt cgtcaaatca tttcttaatt cttcaggcga
    28441 ttctgctaaa gcgcttacaa caagatacgt tccttttggg aatgggatga ttcgcgtagt
    28501 gtttggaaca tcctgactcg tttgaacacc gacatagtac atcattttcc cgttataggg
    28561 ttcgttgact gtaaagaaat aatgattttc agcagcttgt ttcaatgcat ctattgttcc
    28621 attaccgata actttttgct caaatgcttg tttctctgca gccaaaccga caaaatccgt
    28681 attgctactc ttcaattcca caccaatacc cgtcaccgta aaatctggtt tttcttcgat
    28741 cctatacttt gccatttctc ccaccctttc tattatatta agttcatctt acataaaatt
    28801 aaagggaaat gacacgatta cgctcttttt tctagggata tttttatttt ttaactattt
    28861 ttttgctttc actgcaatcc aaatctcact gtaaacatta ctgaaatcct ctccccattt
    28921 tgtaaaagag atctcgggag cttcgactaa cccataatct gaagaaggaa gccattctgc
    28981 atagattttc ccccaagtat cttgtaaagt ttggggaaat ggccctttat taggaaaaat
    29041 ggcccaagtg tgttcttcta tagcaagcat ttctaaatca gcgtacggat tttcttttgt
    29101 cgtagcaaag ccaatcatgt gcatcaaact gcccttttct tccaagcggt ctccatcaaa
    29161 tccataagaa acgttgatta cttgatttgg atataaatct cctaacttat gcatctcttc
    29221 cctttgagtc tccgtgatcg tctgcgctaa cttttgtatt tcttgattga ctccttcaaa
    29281 tttgacagga acttttttcg ccacacctgc cacataaaac tgttctttct tttcgatacg
    29341 aaattccatc gattttcctc ctctgacatc aataaaaaat gtcaagcgtg gaaaagattt
    29401 ttgtatgccg tatctactga tttctgaagg cagatatcct gaccaatcac gaaaagctct
    29461 tgaaaaacct tcgactgttt catatccata tctaaacgcc gtttctgtca ctcttgatcc
    29521 atctagaaga tcgcgattag ccaaagccaa tctacggttt ttgatatagt ccattagcga
    29581 catccctgca ataaacgtaa agatgcgttt taattgatat tcagagattc ctgtattttc
    29641 ggctattatt ttataggaaa gtccttctgt caaatgttct tcgatgtaat cgatcaattg
    29701 gttcagatct ttaagcatat ttatcttcct ccttgattgc ctttttatca tattatcaaa
    29761 gaaagtcaat tacttgatga atcaggaacc aatttagtca gatgtagaaa atgttgtatg
    29821 gatctaaaga aaattctcaa gcagcgtttc gtaacggata attggtatta tctgcctatc
    29881 tatgttttac ctttagaaaa ataaattttg gggaagacag attctaagta aacaaagcgg
    29941 taaaaatatc ttttattccc ttagttaatc cgcttactac ctactgtaca aagcaaattg
    30001 ttgttcaaac tgctgatcag aacgctgctt ggatttttct ttgcgataca tcatacctct
    30061 tttatcaatt ggaacaatta tttatttcta acaaaatcac ttcatttttg tcagataaat
    30121 aaaaaacaaa aaaagttcca tctttaaaac acgctattct tttacttttt ctcacattct
    30181 ctaagaaaag aaaaggagaa tgaatttttg acaattcgag caaaagtgat tatcaaatat
    30241 gtaaaatcag ctactttttt cttaaacgtt tctttatact aaatataaat aagtgtttca
    30301 tgaaaggaga actagatgaa taattggctt gagtattttc ctgaaaacgt tttggaacgc
    30361 ggttacagct atcatctgca cggttttgtc cgtcatttga actatacaag caagtacttg
    30421 tccgcaacag tttctggcac ggaagattat aaggtagtga tcacttggga tgaaaagacc
    30481 aacatgactt gtgattgtct atatgccata gaaggaaaaa aatgcaaaca catggctgct
    30541 gtcttattcg cttacgaaga acgtccaata aaaaaatcca actactcact ttccgaactc
    30601 tcgtcccttg tttcctccgc tagttcctct cttgtacggg agcttttaac agagattctt
    30661 atagaacatc cgcactttat cgaacgcttc aaagttaaga tgccatttca tgcaataaat
    30721 tattcagata aattaacaac tatcatccat aaatacgatc atattatcaa gaaaaacaaa
    30781 aacaggaaaa cagcgaagtt catcatggag atgcgaaagt tcatccaaga agcagttgaa
    30841 tcgcttattc agcaaaatgc ctatcttccc gcattcgaat tgatcaatga agtgattgct
    30901 actctcgaaa cattctattg ggagcctgag gatgaacgaa cccttcttct gatagaggac
    30961 tgttattatt tatggaaaga attattagca gaagcacctc atgcagaaaa aaggcaaatg
    31021 ttctcttggt tcgtctgcca agtcgatcat actgacgcct cttattcaaa acgctactct
    31081 ataaaaatcc tgaaagaaga ctttcgggaa aaagaatttt ctaaccaaaa gaaaaaaata
    31141 gataaaaaac taaagaaacg gtaaagaaag acgatttcaa tgaaaaatag caagtaaacg
    31201 ataacaacca tcctaaatcc acaagaaata cagcagacct tgctttaaaa acacgaatca
    31261 tgcaaaggat gaagtaaaga agacttaacg cgtacccaat attagtcatt tgactattag
    31321 gtacgcgttt tgttttataa gtcatgacaa atttccttcg ttgctggata gattttccgg
    31381 cattgttgat agattttatg atacttttct acattttgta agagaggttc cgctgcatct
    31441 gtatattgga taaaattctg acaacaactt tcaggtgtgt cgaaccaccc taaccctagt
    31501 gcagcaatca ttgttgcgcc taatgcaggt ccttcctcca tacttaaaca atagaccgtt
    31561 gcatcgaaaa tatcagcttg gatttgtagc catgcaagat ttttcgcgcc tcctcccacc
    31621 gaaacaatac gtgtaaatct gcgacccgct agttctttac gtttcaatcc caccattgac
    31681 aaatgctcat taaaaattta gaatattcac aagtttaacg acaattatga aaatttatgt
    31741 cgtgctaaag gagttttgtt attggatgaa aagttagata taaaaactgc gatcaaagac
    31801 acgttaccta ccgttttcgg ttatatcggt attggacttg catttggtat cgttgggaaa
    31861 gctgccggat ttcatccact agtcgtcacg ttgatgtccc tgctggtcta tgctggttct
    31921 gcccaattta tcacagtcag catgcttgct agtcacagcc cattgctttc catcgttttc
    31981 tcgacctttc tagtcaattc ccgaatgatt ctgatgagta tgacgattgc tccttatttc
    32041 aagaaaaatc ggctgcttca aaatctgctg attggcacat tgctgacaga tgaaagtttc
    32101 gcactgggaa tgaataaatt gaactatact ggacaaaagt taaactttcg ttggatgaat
    32161 acagctaatt ggatttctta tttgacgtgg gtgggttctt ctcttgttgg cgcactttta
    32221 gggaatttta ttactgatcc gaaaaagttt ggtttggatt tcgccatcgt cgctatgttt
    32281 atcgggttac tttatcttca agtcatttct gatagaaaca cctctaaacg attacagttg
    32341 atcctgattg gtctcacttt gattctggta tatgtcggac tgatttttat cccaagcaac
    32401 ttagtgattg tagttgtaac actgattggg tgcggattgg gggtgtggat caaacatgcc
    32461 ttcttttgag tttacattgc tgactatttt aggttgtact ttagcaactt ggctttctag
    32521 ggtcctacca tttgtcttac tgaaaaaatt cgatttaccg caaccgttgc ttgagtattt
    32581 aagttttgtc ccgatcgtca ttatgtctgc tttatggttc agcagtctat ttacccaaaa
    32641 tatcggacat ctgccgcaga tcaatctcga aaatgctttg gcttcagttc ctacactttt
    32701 agctgctatt ctttcaaaaa gcttattggt gatcgtcttg gcaggaattc tttccctttc
    32761 gttgattcgc ttattataaa taaaaaaaca agagcttatg gcaaattact gtcatgcgct
    32821 cttgttttta tcaaagtcaa ataagaaaaa aatcggcgta ttcttgctta tccgttgaac
    32881 ggaccactaa caacgacttt tcctaacata tgtcctgttt ctacgtcttt ggttgcttgt
    32941 ttcaagttct tcgcattcat cccatctgaa tagaccttgc tcaatgtact gcggataatc
    33001 ccttcatttg ctaaagcagc aatgtgcgct aaagcttctc cttgcgtttc gatttcatag
    33061 ttatagtctg ttttagcgaa catatactcc cagtcgaagc tgatagattg gtttttccaa
    33121 acacctatat ctaacggctc tttgatccct acgatcgttc ccacatgtcc aaatggtcgg
    33181 acaaggtgct tgatttgatc aaagtagcgg gtaatatcga ataatacagc gacatactct
    33241 acttgatcga ttcctaattc acgaaaactt ttacttaagt cgtgatgata atcgattgga
    33301 tagtctacac ctgttttttt cagccattca aaattcttcg gacttgcagt cgcgtagact
    33361 tctaggccag cccaatgcgc tagttgattc aaaatcgaac cgacgccccc ggatccgttg
    33421 atcactaaga tttttttccc gcgattggca ttttcttctg gagttagacc aaatttttca
    33481 aataacaatt cataagcggt caatgaggtc aacggcaagg ctgcagcttc ttcatctgaa
    33541 agattttttg gtgcaagagc gacaatacgt tcgtcaacta gttggtattc ttgattgctt
    33601 cctgctcttg ttgttgtacc tgcgtaaaaa acgcgatcgc cgacagaaaa tttttgcact
    33661 tcgtcaccta cagcaacaac tttcccgact ccatcaaaac ctaagatacg taaagcattt
    33721 cttatcccgt tatcttggcg aagtttcgta tcgacaggat taacagatac tgcgttgact
    33781 tttaccagaa gatcccgtga actgggtaca ggtatctgtt ctttttcatc aataaagctt
    33841 tttggatcat cgatcggcaa cccttcataa aaaccgacta ccttcattaa ttccttttct
    33901 gacatacgaa ttcctcctta gcttcatcaa gttggagcat ccatacagtg ttcatttcaa
    33961 tatatatagt atgctatttg ttccaccttt tttattcatc ataattattc tcttacttaa
    34021 agtaaactat ttgcactttt ttggttaaaa aagaggttgc gacaagactt ttgtcacaac
    34081 ctcttataaa cggtgttctc ctaccaactc ttcggtcaca agtcaaaata ttcatcaaac
    34141 atgagaagct gttttttgaa attgctcctt gtgactcaga gttaaacggc aggctcacaa
    34201 cctctgatat aaacggtgtt caatcaactg accctcggta ttagctcaaa aaacgacaaa
    34261 atatgaagag ctatttttgt ttggctgttc ttattacttg atacaggaca gctttttcac
    34321 gacctctaat tcacggtgtt caagcaagaa atcattgttc actgaaaagc gttggatgtt
    34381 ctttttcaaa ggtctctaag atctctcgta cttcatcagt agatttcgta ttcatcaact
    34441 gaactcgcaa gtcatttgct cctggaaatc ctttgatata gattttaaag aaacgatgta
    34501 gtcctgtgat ggaacgcggg atgatttctg aataatgatc ttgcagatct agttgcagac
    34561 gaagtagtcc gatcagttct ttttctgtat gttccctcgg gtctttttca aatgcataag
    34621 gattcttgaa aatccctcgg ccaatcatga tgccatcaac gccatatttc tcggccaatt
    34681 cttctcctgt ctggcgatcg gggatatctc cattgatcgt gattagtgtt tgtggagcga
    34741 tttggtcacg taaagcaatg attttaggaa tgacttccca atgtgcatct actttactca
    34801 tctctttacg cgtacgcaaa tggacagaaa gattggctat atcttgatga agtaggtgac
    34861 tgatccattc ttccatctca gacatttccg tatagccgat acgcgtcttg acgctgacag
    34921 gcaaaccgcc agctttagct gcttcaatca attgtgccgc tacttctgga cgaaggatca
    34981 agccactgcc ttttccacgt tctgctacat tagggactgg gcagcccatg ttgatatcga
    35041 ttccttggaa gcccatttct gccatagcaa tgctcatttc tctaaaaaat tctggcttgt
    35101 ctccccaaat atgggcaacc atcggctgtt catcttctgt aaatgttaat cttcctcgta
    35161 cactgtcttt tccatctgga tgacagaaac tgtctgagtt tgtaaactca gtaaagaaga
    35221 catccggtgc tgctgcatgc tttacgacat ggcgaaatac aacatctgtt acatcttcca
    35281 ttggtgctaa aacaaaaaaa ggctttggca gctctttcca aaaattagta gtcatttatt
    35341 tgttactctc cattctatca agcagtgaag tcgcaatctt tctcaaaaac attgtcatta
    35401 tactaggaaa caaaaaaaga agcaaagtga acagcttaaa agatgtttct gattgagcaa
    35461 aaaaaagact gtgacaaaaa tcttatcaca gtccattttc cggaataaat ggtgttcaaa
    35521 agcttgcatt tgcggtaata agtccaacca aacgaaaaat aggaggagct atttttgttt
    35581 ggctgttctt attacttgat gcagaacagc tttttcacaa cctctccact aaacggtgtt
    35641 caatcagctg accctcggta ttcgctcaaa aaacaacaaa atatgaggaa ctattttccc
    35701 gtttgtttct ctaatactca ggtcaaaacg ctgatttcac aacctctttt ctaacttctc
    35761 aatcctcttc ctttattgat caaataccaa gtaacggcgt acaaaacaac gatgaataac
    35821 acaagtacga tcatcgatgt tgctactggc acatcgatcg ttccaaggaa tccgtaacgg
    35881 aaaccggaga tcatataaac gatcggattg acttttgaaa cagcttgcca aaagggcggt
    35941 aacatagaga tggcatagaa aacgccacct agataagtta acggctgcaa gacaaatgta
    36001 ggcacgatcg atacatcatc ataagactga gcaaaaatcc cgttgagcag tcctgctaat
    36061 gaaaacaaga ttgccgtcat caataatgta atgatgacca tgaaccatga atacacatga
    36121 agtggtacaa agaacaagga aatgatcgtt acgagagagc cgacgagaat actgcgaccc
    36181 acaccaccaa tcacaaagcc ccaaataatc acatgcgtag gaacaggtgc taccaagatt
    36241 tcttcgatat ttttctgaaa tttttgagag aagaaggacg aagaaacatt ggcatacgaa
    36301 ctagtgatag cagacatcat aatcaaacca ggaacgatga attccatata tgaaaaacca
    36361 cccatgtcac cgatccgccc accgatcatt tttccgaaaa taacaaaata caaggatgtc
    36421 gtgatcactg gcggaaccag tgtttggacc catatacgca aatagcggtt cgtttccttg
    36481 atagctaaac tttttaatgc agtaaaataa agattaaaca tttttctcct ccgtatgatt
    36541 attttcttct gtgattttca agaacagttc ttctaaacga ttcgacttat tcctcataga
    36601 aagaactttg attccttgtc ttgtaagctg atcgaagatt ccgttcaccc cttgatttcg
    36661 ttcaacttcg acagcgattg tctgctcatc ttcaaatgta caagcatatc cttcaatcac
    36721 aggtttggta tcatatggcg ctaaatcaaa gataaatgtt tcaaattgca gttttgacag
    36781 aagctctttc atacttgtat tctcgatcag ttcacccgat tggatgattc cgatgttgcg
    36841 acaaagcatt tcagcttctt ctagataatg cgtcgtcaaa atgatcgttg taccattttc
    36901 gttcaattct cgtagaaact cccacatctc gcgtctcaac tcgatgtcaa ctcctgctgt
    36961 tggttcatcc aagatcagca aacgtggttc atgcatcaat gccctagcaa tcatcagtct
    37021 tcgcttcatt cccccggaaa gcatacgtgc acggacattt ctcttttccc aaagattgga
    37081 ctgcttcaaa tatttttcgc tgcgtttcat cgcttctttg cgagagacac cgtagtagcc
    37141 tgcttgattc acgacgattt gctggaccgt ttcaaaaggg ttaaaattga actcttgtgg
    37201 aaccaatcca atctgttgct ttgctcgaac tagatccttg tccagatcat aaccgaagac
    37261 attcactttt ccagatgttt tattgactaa agaagtaata atcccgatcg ttgtagactt
    37321 cccagctcca tttggcccta atagcgcata gaaatctcct tctttcaccg aaagatcgat
    37381 tccccgcaat gcttcgaccc cacttccata gatctttttc aaattattta tttcaagcgc
    37441 atttgccatt tatttcctat ctccttatag acatgattct taattgtatc atggaataca
    37501 gcagatgaaa aaacaacttg gcttccacac aaaaacacac ctgctaacaa agaggagatg
    37561 tgttttctag ttcatgatca tcttcgatag aataactatc taaacaactc tggaactttt
    37621 aaaatcataa aagtaccgac agcaactact acgatgacat atagaagatc cttataactg
    37681 aggttcttgt cttttttatt catgttaagc tttcctccgt ccttttatcg aaagcttttt
    37741 tcttttattt taaccgaaat aaataaaatg gaaatagtta ttttcaattt ctgttttcgc
    37801 tgtttgtttt acggagaact ttgccatgga acgtgcgtct cgtcgctgat gctaagtttt
    37861 ttcgataaaa gctgctagaa ggaagacagc gtggtttatt ttgtatcgtc ttttgctaaa
    37921 tcttccaaga tcatctggac agcagactcg ttcccattga attctgccac ttttttggca
    37981 tcaatgtact tcttttgata atcgtctttt tggacccacg catcatgctt cgtttgataa
    38041 agttaatcaa acggatacca ctgacgctgt tcatcgaaca acaaactttc tttttgggcc
    38101 tgttcaacta tggatttagg ataattcaaa actttcagca aggcaatcgc atttcgggtc
    38161 cttgaaggtc cttcttttaa tttgaaatca aaactgattc cttttccttc tgttacttgt
    38221 tcttcaaagt ggacattctc acaataattc tttaaaatct ctgtcaattc gatatcatgt
    38281 gtggcgacaa atgctaaaga tggatactcc gcaagccacc gaacgactga agcggaagaa
    38341 gcaatccgtt cgatcgtatt tgttcctttt aaaatctcat ctacgaagca gtagcagcgt
    38401 tctttggaag ccacttggtc cagcaaacgt ttgatcgatt tgatttctga aacaaaataa
    38461 ctgtcgcctt caaataaatc atcttcgatt gccatggaag tcaacacatg tccaggttgc
    38521 agggtaaact gttctgcaat cgctgtttgg atcgtctgtg ctagaataca gctgatggct
    38581 atacttttga catacgtaga ttttcctgat gcattggaac ccgtgactaa tgtattcttc
    38641 tgccagttga ctggattaac taccgcttct tttaacaatg gatgatagat atctttcgct
    38701 gtcacaccgc cctcagtaaa ctctggtcgg caagtgatcg gcatataggt gcgataattc
    38761 aaaacggctg ctgcaacttc caattctccc agcaattccc acagcttgat ggcttcagtt
    38821 gaatgctttt ctaatttagt gagaacgaaa tgataggaga taaatggcag catgaacatg
    38881 atgttgacat attcaaaaat caattctgct tcactcccgc tcttcattcg aaatgaaaaa
    38941 cctaatttag ggatgtctct taatggttta gtttgctgtt tcagctcttt ttgaagtggt
    39001 gtcgtcattt ttgctaactg attggcggct gaaatcgttg aaaccaaata actcatgcta
    39061 ttcagctctg tttctagtgt ttgtttcttc actagataat agaccgtatt gaatactaag
    39121 ccaccgattg ctagatagat tcctagtact tgccctaaaa gaagcaaacc tacacccacc
    39181 agcggaagca agccaagaaa aataaataaa cctacgcgtc caatcttttt actttttcca
    39241 tccgctagat attgttttgc aaaattatga tctttttttc ctaaacgagc gaattgatat
    39301 tggattcttt ctctcagttg aggattttcc tgataaaaag caattagttt ttctaactga
    39361 taatcttctc caaaatcaaa gctacgtaaa cgctgataca acgcttctga acctacacta
    39421 gaataggtac tgttgatccc ttcaaatact tcgaacatat ccaagtcata ccaagtaaga
    39481 tcgtcgattt cactatccca tgaacggaat tttttctccg tgagccacgc atccttcaaa
    39541 ctttcttctt tatcaaatct cggttgataa ggaatttttc cccaattact acgaactgtt
    39601 tcctttactt tcaaacgtga aaaaatgtct aaaacaacta ataaaataac aactgcaata
    39661 ataattaaaa cgataaattc tctttggccc atatccctct ccgttccttg atttgttagt
    39721 tttagtatag cactgttgcg ctatttgaaa agggggtaca aaaataactg tcttcgttac
    39781 ctaattcgta tcaatcacac caaaataaaa acaccttcca aaaaagaaga tgtctttaaa
    39841 acgagataca attttttgtc attcacttca ggtaaattag agccaattaa accctccgca
    39901 acttgacgga gatggagaag atgcccccgt ctaatctagc ggtcatctct cctcccattc
    39961 cttccaccaa tttttttgac aggtaaagcc cgattccgct agattccgta tttgtgcggc
    40021 tggtattttc ggtataaaaa cgctggaaga ctttttcaac agaggtttgc gctcctggtt
    40081 tgataggatt ggccactgtt aatcgaatga atgaatcctc ttttgaaaat gtcacctttg
    40141 cttgtccatc tgcataacgc aataaattct gtatgatatt ttgcagcact cgcagcaaca
    40201 tgagcggatc tgctaataca gttgtattta tcgagtgttc agcgaacgct acctcgatat
    40261 ttttctcaga aaattgttca taaaaagaga aaaatacttc ttccacctct ttagaaaaag
    40321 aaagcgtatg gagatccatt tctttttgct tcgtctctat tcgagcaaga tcataaaact
    40381 gatccgtcat actgagtaat cttgcaacag attgtttgat gatcgttaaa tacttctccc
    40441 gtttctccgt atcctctacc tgttccagta attgtacata accgttaata gcagtcaaag
    40501 gagttctgag atcatgagaa aggccgacga tcgatagtct gatgttttct tccatttctt
    40561 gaaatgcttg tcctttttgt tcattttcat ccacccatgt attcagtgca tctactaggt
    40621 ccattagatt cttttctcga aattcgactg aaagacgacc accatattct tgtcgttcag
    40681 aaagagtggc gattttctta gttaatctct tgatttccct ttgcaggaag aaaataaaac
    40741 ttcccataaa gataacaacg agaagcaaca gccacttaat caaatctaaa ccccactccc
    40801 cacaccgtat gaatatacac agcatgtgcc tttgctagtt tccctcgaag attggaaata
    40861 tgcatattca ctgttttctc actatcaaaa tatggttctt gccaaactgt ttcataaaga
    40921 tttgctcgcg aaaatacttt tttcggatgt tctaaaaaaa gcttcagcag atcgaattct
    40981 cttcctgtca aatggacagc cacaccattc acatttacat ccctcgactc tttgtccagt
    41041 aagatttcct tgtaatagat gcgttgcgac agatctttta cttggacaga agtctgatga
    41101 cgaagttgga tgccgattcg taacaacagt tcttcgatat caaatggttt cgtcacatag
    41161 tcatccgctc ctgctgccaa caaggaaact ttatctcttt gatcgctttt tgctgaaaga
    41221 acgatgatcg gaacattcga tgtctgtcgg atttctgcta acaatgcttc acctgaaagc
    41281 cctggaagca tgagatctag aaggatcaaa tcgacaggat atgtgcttaa caataatttt
    41341 ccttccgtac ctgaataagc atcaagaagt ttgtatctct gttcaagaac ctcctccagt
    41401 aaagaatgaa cagcttcatc gtcttcgata atcaaaatag tttccagcag gaacacctac
    41461 ttaatgtcag atttttggaa aataaacatt cctagagctg atgataccac gattgttact
    41521 agactgacca gaatcatttt cggtgcttgc gaataagttg cttgttgcgc aaagtccgta
    41581 tacatgagcc acgtttccgt aaaccactcc gttagaaatt ccaagccttt gatttttgcg
    41641 aaaacaccgg gaacgaaggc cgttcccatg atataaagaa aagaaagaag caaactgaca
    41701 ctggtacttc tagtgatgaa tgtcaaagcc actggaacag ataatgtcgc taatatcagc
    41761 agaagcaata caggaaatac ttttagaaca taatttccat agtttttgat tccctcaact
    41821 tcaccaaatc cgaaagcaag tgtgtaagca atcatggcta gccccgtaat caaaaccacg
    41881 ccaagtgttg tgatcaaaag cgtaacgaga agtttcgaca cataataagt cattcgattc
    41941 cgtcctaaag ataacgtatt gcgaatcgta ccgttttgaa attcttcccc aatataaaag
    42001 cacgcaaatg ctgcgaaagc cagaagaatc catgcagcca ttttttccac cattaaaatc
    42061 cctgttgcac cgttgatgac tgtatccgtt gcttggttta attcattgcc gtattttgta
    42121 tgcatatacc attcgttcca agaataaaaa agcggaagta cgaccatcag tcctagtgag
    42181 acccacattt tacggctctt ccatactttt attttttcag cagttaatag attaaacatg
    42241 tggattgcct ccagttaatt gtaagaaata atcttccagt ttttgcccaa ctaggtggat
    42301 accatccaca ggaacttttg cctctaccaa tgcttgattg atggctgcta cttggtcaat
    42361 tccttcaaaa agctggataa cacggctaga ttggacaaaa taatccctat aaccaagaga
    42421 gtcgagaacc gttactgctt gttccgtcgc cgaagtgtca atttttataa attgacgaga
    42481 ttcttgtgcc aattcttctt tcgataattc tttgatcaag tgtccttcat gcaaaatacc
    42541 gtagtgagtg gcgatctgtg acaattcatc tagcaagtgg ctagaaagca agacggtgat
    42601 gccccgttct tttaccaaac gttggatgat ttctcgcatt tctgccatcc ctgctggatc
    42661 catcccattc gtcggttcat ccaaaatcaa aaattctgga ttcgtgatca gtgcatttgc
    42721 aatagctaaa cgctggcgca tacctaaaga gaaattcttt gctttctttt tccctgtatt
    42781 ttccaatcgc atcattttca gcaggtcttc gatttctcta tccgacacac cgccgttcgc
    42841 tgcttggata cgtaggttat ctcttgcagt taattctgga taaagagcag gggtttcaat
    42901 cgattgaccc atacgtcgtc ttgctgcctg caaatccgtc gttccaaata attcgatcga
    42961 accttcatca atcgagatca aacccataat agttctcata aaggtagact tacccgctcc
    43021 attctcccca atcaaaccat agatcattcc acgtttgatt tcgatcgata ctttatctaa
    43081 tgctttggca gcaccgtatt ttttggttat accagttgct ttcaagaccg tttcatttcc
    43141 aaaatccata cttatccttc tttcttattg ataagtgaag tatagttgac gggtataaag
    43201 aaagcagcca gaaatgtata aagaaagtgt aaattttcca attgaatttc aagaaaaatc
    43261 agactgtctc gcagacgtgg ttgagttgtc tgccaatcaa agagcgcacc aaacagtgct
    43321 aatccaagtg gactggccac catggtaatc gttgttatcg ttgacatcag acgtccttgt
    43381 atatgcgttg gaacttctcg ctgaagccag accatataaa aagcaaaaga aaacattaat
    43441 ccttaaaaac ggacttatga aaaataatac atgccgtttg ggatttacaa ttagctacca
    43501 aataagaggt tatgacaaaa gacttttcac aatcccttct tccgaataaa cggtgttctc
    43561 ctgccaactc ctcggtcaca agtcacaata tttatcaaac atgagaagca atttttgtaa
    43621 attccttctt atttcttgaa gctgaccact tctgtcacaa cctcagaagc ggataaataa
    43681 tattgtttga tgatacttta tctttttccc gtttgtttat agatcgaatg atattataga
    43741 ccaagaatcc tacctattaa catagctaaa aacacaaaaa aggcactttc caaattgtgg
    43801 aaagtgccag aaaagttagg attaaggtaa ctgcgctcag cattgcttcg cccagtacga
    43861 ttctcgtaac tcgtgaactc gaacgataat cgcaattaac gttttgagat gtgactcgta
    43921 cttattacaa gtacttctat caatagaaat ccaattatat caacattaca aacatctaaa
    43981 aaacagtttg atatggataa aataggatta atattgatat tacttgaacc aatttgaacc
    44041 aaagatgaat ggtagttgaa tacaattttc ttactagttt atcaatcttt tttagagtta
    44101 ttcctcccct cttatttatt tgagaccgta ttgatggctg gatagctgtc taataggggt
    44161 ttcaaggcca gaattagcta agctactaga ttctcgaata attgtataag ccggtcacac
    44221 ctacttaaat gtgattgaga aggtcaaata tagggtcaaa aaatactcgt cagtatgtca
    44281 gatagataaa tccaatttta cgccaaaagc agatcctttt ctcttaaaat agtaagagcc
    44341 atcgaagatt tatgtttcac ttcgcacggc ttttacttta attttccaat ttatcaaaag
    44401 gacattttac gtctttttat cttttaccga gatagatgac agttgctact taatctagca
    44461 aattcgctac acgacttttt atatcatctc taatttctct gaatttatta atgatttctt
    44521 cttctgttcc agttgctttg gctggatctt ccaaatccca atgaacatgc ttaatccctt
    44581 ttggaattac tggacattta tctttggcat cgccacatag cgtaataatt aggtctgctt
    44641 gattaaaata atccatatcg atcaaatcag atgtttgcgt agagatatct atcccttcct
    44701 cagccattac ttgaacggct ctaggattta acccatgttg ttcaatgccg gcgcttttaa
    44761 tttcaaattc atctgttggc aaaatcgctt tcccatagcc ttctgcaatt tgactacgac
    44821 aagaattgcc tgtacataaa aagtaaattt ttctcattat tatttcctcc gatatcagac
    44881 aattctgatg gattttgaat gaaccaattt ttttgtgcga ttagatattt taactaacag
    44941 taacatgact ggcacttcaa ctaagatgcc aactgccggc gcttatgtaa aaatatagat
    45001 aatcatctat gttttgtcaa atgcttctgt ctttcagttc aaattaatta gtttattatt
    45061 tgcattcgat tcaatctaat ttgaaaatca ctacttatat agatgcatcc atacaatcta
    45121 tataactcct cacatattca aattaaaatt tgattattct attaatctat gatacactac
    45181 attcaaatat ccattagaat aaaggaggag ctgtatgaaa aacgaaattt gtgaaatctc
    45241 atgtgttcat gaagataaag ttttactagg aaaagaaaag ttacaaactg aggatatttc
    45301 gagcttaaaa agtgtcttca aaattttagc tgatgagaat cgcttaaaaa ttatctacgc
    45361 cctaagttat gaggatgaat tatgtgtatg tgatatcgca gcaactatcg aggcaaccgt
    45421 ggcaacaacc tcacaccatt tattatcatt gaaaaaaaat ggaattgttg tgagtcggaa
    45481 agtagggaaa ttggtttatt actctatcaa gaatgataaa tttgtccaac tactaaattc
    45541 caaactgtat ttagaagatg aggtgctagt atgagtgaaa aaaaacaagt ctatcgggtt
    45601 gaaggattga gctgtacgaa ttgtgcggca aaattcgaaa aaaatgtttc tcaaatacca
    45661 aaagttaccg atgcaaaagt aaatttcggt gccggaaaaa tctctatcga aggcgaagcg
    45721 actattgcgg aaattgaagc tgcaggagct tttgagaatc ttaaagttca gtccgaacat
    45781 gatacagaac ctcgcattga aacaaaagag ccttttgtga aaagaaactg gaacctattg
    45841 gtttcactgt ttttaattat tttggcatta ggatctcaag tagttaacgg tgaagatgcg
    45901 ctattaacag aaggattatt tatactagca attattatcg gcggatttag tttgtttaaa
    45961 gaaggatttt cagacctatt aaaattgaat ttctcaatgg aatctcttat gacaattgca
    46021 atcattggtg ctgcaattat tggcgagtgg actgagggct caatcgttgt tatcttattt
    46081 gcaattagcg aagctttaga acggttttca atggataaag caagacaatc aatacgttcc
    46141 ctaatggata ttgctccgaa agaagcatta attagaagaa ataatgttga acaaatgatt
    46201 aatgtttcaa aaatcgaagt aggcgatatt atgatcatta agcctggaca aaaaattgct
    46261 atggatggtc aagtcattaa aggccattcc tcagtaaatc aggctgcgat taccggtgaa
    46321 tctgtcccta ttgaaaaaaa tattaatgat gatatctttg caggaacgat taatgaagaa
    46381 ggtgcacttg aagtcaaagt tacaaagcat gtgaacgaca cgacaattgc caaaattatt
    46441 cacctagttg aagaagcaca aggtgaacga gcacctgctc aagcatttgt cgataaattt
    46501 gcgaaatatt atacacccac cattatggtg attgccgcat taatcgtcat cgttccccca
    46561 ttatttttta acggagattg gaatacttgg ttgtatcaag ggctctcttt attagttgtt
    46621 ggctgtcctt gttctttagt aatctcaaca cctgtgtcta tcgtttcagc aattggaaac
    46681 tctgctaaaa atggtgtttt ggtaaaaggc ggtatttatc ttgaagaaat tggtggcctc
    46741 aaggcgattg cctttgacaa aacaggaaca ttgactaaag gaacaccaac ggtaacagat
    46801 ttcactacag ttgattcaaa agacgaagag aaatatttct caattattac agcattagaa
    46861 tcatattctc aacaccctct cgcgtcagca atcttaaaag aagctgataa tagagcgatt
    46921 tcttataaat cagtagttgt tgacgagttt acttcaatta ctggaaaagg aatacaagga
    46981 aacattgagg ggattaccta tcttgtaggg agtccaaagc tttttgaatc tatcttaaca
    47041 gataactcaa agattattga aaattaccaa agacttcagc aacaaggaaa aacagcaatg
    47101 ctcttaggaa cagataaaca aattttagca gtcattgcag tagctgatga gttaagagaa
    47161 tcaagtaaag cagtcattga aaaattacat gatttaggaa tcgagcatac gataatgctg
    47221 actggtgata atgctacaac tgctcagtca atcggaaaac aaacaggtgt aactgaaata
    47281 aaaggcgatt tgatgcctca agataaatta gattatatta aatcacttaa ggaaacctat
    47341 ggaaaagtcg ccatggttgg tgatggtatt aatgacgcac cagcattagc tgcctcaaca
    47401 gtcggtatcg caatgggtgg cgctggaaca gatacagctt tagaaacagc tgatgtagct
    47461 ttaatgggtg atgacttaca gaaacttccc tttatagtta aattaagtcg acaaacattg
    47521 agaatcatta agcaaaatat taccttctca ttgggaatca aactattagc attattactt
    47581 gtagttccag gctggttaac gttatggatt gctatcttag ctgatatggg agcaactata
    47641 ttagttacct tgaacggctt acgactgatg aaagttaaat ctaaatagac aagtagtagc
    47701 ataaaaagag gaaagactag cgacggcagc gccgtataag ctagtctttc ctctttttaa
    47761 tgctgttgca ggacggcgta gccggactgc atgggcaagc ccctctttct aacagggggc
    47821 taacaaagaa caggaaactg tgacaactac ccatttggga gtgtcctagc agtgttttct
    47881 ttgtcacatg cttatcaatc ttgtcacctc attttgatga tggatacgct acgtttaaca
    47941 gacgttcttt ctcgacttcc atcacgaatg gtagataaag atattgttgt tctagtagat
    48001 attgattgtc ctctgtgtac tgataagaag ctgtttcttt tgaatagacc aacggggcaa
    48061 ttcgcacatc gacggtcaat tgattgatcg agtatagaag aatggctttt tcaactagtt
    48121 ccttgggcaa atgtttccca aaataggaat aggattcttg atttgctaaa tagacgagta
    48181 agcgatccac actaaagttg gaaaaggtaa agggcagaat gtgcagaatg tgattttgat
    48241 tatcatggtg taaatagagt tgagcttctt taccaaattt agttgaacca aggtaaagct
    48301 gctttttctc atcgatacat tgataagtaa attggtcttg ttccgttggt ggaatgaggt
    48361 ttataataaa aaattcaatc atccgatcca tttctttttc actaacaaga ccggcttgtt
    48421 tcagttcgtc tactattagc ccttcaatct taggatcaag cttacctgcc ttcttttgaa
    48481 gcatttctaa aatgtattgg ttttcttgag taccatacaa aagatattcg ttggtgacat
    48541 ggcctatttc tgcaatttgg tgaagggttt cggtttttgg aaggttaatc ccacgttccc
    48601 agttattgac tgtacttcgt ggtaaatcac caattagttt gccaaatttc tccatactca
    48661 actttaactc ttgacgaatc tgccgaattc gattgcccac tgcttgcttg tctatctcca
    48721 tgaaaactcc tcctcatgat aagttcttaa attcagtata cgcttgtact taaaaaaagt
    48781 caaaatgtat tgacttaaaa taaatacagg cgtacaatcg atttgtactt aaaataagtc
    48841 tgatggttct ttgacaattt aatagcagaa ggaggttttt ctatgaacca agtcaatcaa
    48901 catgatctcg gggaatcgat tcgagtttct cgagaagaaa gggggtggac ccagcgatat
    48961 ttagcagaaa aagtggggat ttcgagatcg ttattatcga aagtagaaaa aggaacgaga
    49021 caattaagtg cagaaaaatt gaatcttata ctggatagtt tgcaagaaga gatcgttcca
    49081 gttaatcgtg ttttgattga ttatctaact attcactttt tctcgaatca acatttaaag
    49141 ttgattgaag caattattgg catgcctatt gaacgctttg aggaactgga ttatgcgcca
    49201 aagggctata ttgggcaata tgtttggaat caagtaatca cgattcggta ttccattgac
    49261 gatacggtaa aaggaaccgt aatggagttt tcaggtcaag gctgtaaaca tcttgccatg
    49321 cgtttgaaga ccgcaaaatc aaactggcaa gagttcttcc gtaaggtatt agattatcag
    49381 ggaaacttta cacggattga ttttacttta gatgattttg tggggagtct cagcattcca
    49441 gaactgaagc gtaaggtaac actaggccat gtgtggacca cttttcaagt gagtgaatct
    49501 catggcggta cggatatcat aaacaatgaa tcaaatggtg agaccttgta tttaggctca
    49561 aagaagagtc agtgtcgctt ttgcttttat cagaaggatt atgaacaacg aaagcgacga
    49621 ggaatttctt tagaagaagc agaagtaaaa aatcgctttg aactacggta tcgaaaagag
    49681 aaagcgcaaa gcttggcaaa gattatttca aaaacccatg atttaaccaa actattcttt
    49741 gagttactta atggagcaat ttgtttttat gaccgtgctc caaatgatcc aggtgcaaaa
    49801 gtcgatgcca aatgggcagc ctttattggc aatcatggcg caaccaccat ttctttagaa
    49861 acaattcctc aaagctttga gaaaagtatg aattggttaa ttcacagcgt ttctcccacc
    49921 ctcgcattta ttcaagaggt agataatcat tttgattcaa atttgattaa cgagattatt
    49981 agctgtgggg aacttagttc aaggcagcaa aaaatattag aaaatttgat tgctgagcct
    50041 gattattatc aggaagaagt agaattttat atccagtgtc ttcaaaatat gaaggcagca
    50101 aaaatacaca aaaaaagcaa agcacagctt acacattaaa atgtataaac gtactccgcc
    50161 ctagacaagt tgagtatagc acatttcctt gtgtcagcca aaaaacattt ttggaaagga
    50221 aataaactat gaaaaataca ataactactt atgaattgcc ctatctactt actagagaac
    50281 aagcttctca ttttttaggg atcgatccaa aatcttttga taaattcgtt cgcgcaaacg
    50341 atgagttaga gcgttttatg ataggaagac aagaacgata cactgtcact tccctcatta
    50401 attttattaa gacgcactct atctagctaa aatatcgtag gatggttgat tagatgcttt
    50461 tcgccatgta gaatgacggt gtattcaact agcatttatc aaccatcttt cagtgaaagg
    50521 atttgttata aatgcctagt ataattaaac gtggtaactc atatagagct cagatctcac
    50581 tttacaatca tggtcaacat aagaaattga caaaatcatt tagctctaaa aaggaagcaa
    50641 ctcgttgggc cttagaaaat gaattggaga aaggaaatgg aaaacaatta gcagagcgta
    50701 caacaacatt tgctgacttc tttgaaaact ggattcatat cataaagaaa aacgatgtaa
    50761 aagaaacgac ttttcaaaat tatcaaagga cttctcaagt ggtgaagaaa ttatttggcg
    50821 atatacagtt aaaggatttg aacgatattg tagtacaacg aaaaatagat aagtatgcag
    50881 aaactcattc tcgtaaaacc actcatgaag tactattgaa aatcaaaacg gcattacgtg
    50941 atgcttatgc tcgtggctat cttgctaccg attttgcaaa tttagtcaaa acacgaggga
    51001 aagttttaga taagagaaac cgtgtacttt ctattaccga attaaagaaa ctgcgtactt
    51061 atgtcattaa tcatcgagaa aatgagttta acattcttgt actccttgcc ttagaaactg
    51121 gcatgagacg cggagagctt ttaggtatac gtcccgaaga cctctttgaa tatggtatcc
    51181 atgtcagacg ttcccttagt ccaacttctg aagatacctc gttaaaaaca aaaaattcaa
    51241 gacgagatat ttccattaat caagaagtct acgatattct aaaatctgtc ccgattaaag
    51301 ataatggata tttttttgat cctgacggct ttcaacaatc tgctaagctc gccagattac
    51361 tgaaaaaact agatattcca aaaactacct tccacggcct aagagatact catgcttctt
    51421 ttctattttc acaagatatt gatattgcct atgtatcaaa acgcttaggt catatcaata
    51481 ttcaaacaac gcagaactat tatcttgaat tgatgccaga aaaaaagcac cagcaagatg
    51541 ctgatgcttt aaacctctta aattctttgt caaatttata atttgaacca acttgaacca
    51601 aaaaattctt gtaaacgttg atacaataag gaattgatta acgttttgag aactgtgaag
    51661 ctttacgggc tttcttaaga cctggttaaa caaaactcta ttttattgca ttttacagga
    51721 atgtatttca tgcgaaatta ataagtcttt gtttatagag ttttactagg gtataaaaag
    51781 ttgtatgtta tcattacctc aaaacattac ctcagcttgg cgagttggtt gattgaagaa
    51841 taaatcattt atctagatat ctcaataaaa aatgatttct aagaaacttg tattttcgtg
    51901 ttattatttt tttgccctat caaaatttct aattcttcta gcgtaatatg attatgacac
    51961 ataatcgatt caattacttc aatacctatt tttttcgaga aagatccctt ttgttcactc
    52021 acaaaaatac tttcagaaga catatataag gaacgaagtt ttggaattag tatatcgtac
    52081 aaatagacca ccataaaatc gtccttgcaa ccattctcaa aaagaattaa atttgctgat
    52141 tgtgttacat atatcactga attacattca tggtcaattc caaaaacaat gtctacttca
    52201 ttttcttttc taattcgcgc agttacattt ttcaaacttt caccattact tataaatgct
    52261 ttagttactg taagctctga tgtttgttca gatattcctt ttataatatt ttgttcatca
    52321 gccacattcc ccataaatcc gccgattcct tttaagtaat aattctcacc taagagtcgc
    52381 ttgcattcac tgaattgata aaaaaaccag ttaaaaaaat cttctggaaa aataaattct
    52441 gatcgaactt tatttatatt tttagctcct attaatttta taactcgatt aatgttcact
    52501 tgctgcgatg aacatataac tgaataaatt gagttgttta attcaaaaaa acaactttaa
    52561 catatgcatc attaattcgt tattttttag gtagatattg atcattgtta tctctctttt
    52621 tttgcttccc atactccaac ttagaaattg ccgttataaa atttatttta aaggtgactt
    52681 tttcccctga agtatcggta gtaggaatac ttaatacctc agcttctgag gaggtatccc
    52741 aattatagtt atactttgca tcatcaccat aaagaacaat tccatttttt ttatcttgtg
    52801 ccgttagctt tactggttcg cttacttttc ttgttaatat cttggacttt acatcatcga
    52861 tattgcttat tttatcaagc ttaaataatt tacaaattaa tttcgtacta gtttttatat
    52921 ttgacgagag tgtaaaatat tttgtgtaaa tagaaaaaag gaagtccctt ctgtagaata
    52981 gagttaccac aacacattca cagaaaagag gacttccata tgaacgattt tactacagaa
    53041 attctaaaga ctctagcgaa caaaggcgat ttgaatgaat tattccgtgt ccatttggaa
    53101 aaagctgtca atacgcttct caaaacggag ttaacggctt tcctcgatta cgaaaagtac
    53161 gatcgcattg gttttaacac ggggaattct cgtaacggct cctatgaccg tacggtcaag
    53221 accgagtacg gggaacttca tctccagatt ccgcgcgacc gcaacggcga gttcaagcaa
    53281 cagactgttc ctgcttatag acggacgaat gataccttag aggagaccgt cattcacctc
    53341 ttccgaaaag gtattaccat gtcggaaatc gcagacttga ttgagaaaat gtatgggcat
    53401 cactacacgc cccaaaccat gtccaacatg actaaagtgc tgactgaaga agtaaatgca
    53461 tttaaagtta gaactctaaa tgataagtat gtcgctattt tcatggatgc tacttatatt
    53521 cctttaaaac ggcaaaccgt ctccaaagaa gcaatctata ttgccattgg tatacgagaa
    53581 gacggcacta aagaagtact aagttatgcg attgctccga ctgaatcgac ctacgtttgg
    53641 aatgagttgt tacaggacat ttactccaga ggggttcatg atgtcttact gtttattacc
    53701 gatggcttaa aaggcatgaa agatacgatt caccagattt atcctaaagc taaataccaa
    53761 cattgctgtg ttcacgtttc ccgtaatatt gctcataaag tacgtgtcaa agatcgaaaa
    53821 gaaatctgtg atgattttaa ggctgtttat caagctagct caaaggaaga ggcaaatacc
    53881 tttttaggga gtatgattga gaagtagcaa aaaacttatc ctaaagtgac gcagtcactg
    53941 ataaaaaatc aagatttatt gactttttat gagtttccgc ctggtatccg ccgaagcatt
    54001 tactcaacta atttaatcga atctttcaag aaacaaatca agaaatacag ccgcagaaaa
    54061 gagcagtttc aaaatgaaga atcactagag cgtttcctag tatccatctt tgatacatac
    54121 aatcaaaaat tcttaaatag aagccataaa ggcttccaac aagtgacgga tacattagct
    54181 tcaatgttta ctgagtaacc cattattttg cagaaggacg agttatttac acaaaattat
    54241 tgacgctccc tccaaattac ttcatcaaaa cattgatata atttttatta tatcagtatt
    54301 tattcttgat acataaatga gaaaataaat actttaaatc tattgactac aagtagtcat
    54361 taagtcttca taagatgtac aatatgacat taaaaaaata aaagcttacg accatccgtt
    54421 aaatctgaca ctaaataatg gactgctttc ttttgtatta gcaggttacg ttgactatga
    54481 atattcacca gattatttgg agaaacctct tcaacacgag aacaatgata ttaattttag
    54541 atttgtctac gagtcaaaaa gtaaaacatg gttagttgat caattaagca cgataaacac
    54601 aagcttccat gaattaccta aacctgaaaa tgaagttgag atggtcatta aaatcttcta
    54661 aaaaagaagc gttgaagggg aaatattcct ttcaacgctc ttttttatat gcttagaaac
    54721 ataaataaat tgtatacttt ctttttagcc cctattactt ttcacgaaaa atatcttttt
    54781 ttcgacgcta gcgtttctct acttctaata ctgtacacag tttttgtatt attgaaaaat
    54841 tactcattat ttagcattaa tccacatcgt tttatcaatc gaccttcata ctaaactact
    54901 ttaaagtcat cttccttctc gtttttcatt
//
LOCUS       DAFEEZ010000010        52626 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000010
VERSION     DAFEEZ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52626
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.010"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            83..970
                     /locus_tag="LP245_000717"
     CDS             83..970
                     /locus_tag="LP245_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBL1518655.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTITSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1110..2036
                     /gene="cysK"
                     /locus_tag="LP245_000718"
     CDS             1110..2036
                     /gene="cysK"
                     /locus_tag="LP245_000718"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBL1518656.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2272..2718
                     /locus_tag="LP245_000719"
     CDS             2272..2718
                     /locus_tag="LP245_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL1518657.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2991..4343
                     /locus_tag="LP245_000720"
     CDS             2991..4343
                     /locus_tag="LP245_000720"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBL1518658.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4514..4801
                     /locus_tag="LP245_000721"
     CDS             4514..4801
                     /locus_tag="LP245_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518659.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            5027..5470
                     /locus_tag="LP245_000722"
     CDS             5027..5470
                     /locus_tag="LP245_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1518660.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5476..6660)
                     /locus_tag="LP245_000723"
     CDS             complement(5476..6660)
                     /locus_tag="LP245_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBL1518661.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6928..7626
                     /locus_tag="LP245_000724"
     CDS             6928..7626
                     /locus_tag="LP245_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBL1518662.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7633..8310
                     /gene="nth"
                     /locus_tag="LP245_000725"
     CDS             7633..8310
                     /gene="nth"
                     /locus_tag="LP245_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBL1518663.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8436..8969)
                     /locus_tag="LP245_000726"
     CDS             complement(8436..8969)
                     /locus_tag="LP245_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518664.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9266..11647)
                     /locus_tag="LP245_000727"
     CDS             complement(9266..11647)
                     /locus_tag="LP245_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBL1518665.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11637..12284)
                     /gene="recU"
                     /locus_tag="LP245_000728"
     CDS             complement(11637..12284)
                     /gene="recU"
                     /locus_tag="LP245_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBL1518666.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12348..12887
                     /locus_tag="LP245_000729"
     CDS             12348..12887
                     /locus_tag="LP245_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBL1518667.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12977..13396
                     /gene="gpsB"
                     /locus_tag="LP245_000730"
     CDS             12977..13396
                     /gene="gpsB"
                     /locus_tag="LP245_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBL1518668.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13418..13785
                     /gene="rnpB"
                     /locus_tag="LP245_000731"
     ncRNA           13418..13785
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="LP245_000731"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13994..15160
                     /locus_tag="LP245_000732"
     CDS             13994..15160
                     /locus_tag="LP245_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBL1518669.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15206..16702
                     /locus_tag="LP245_000733"
     CDS             15206..16702
                     /locus_tag="LP245_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBL1518670.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16783..17466
                     /locus_tag="LP245_000734"
     CDS             16783..17466
                     /locus_tag="LP245_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1518671.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            18111..19301
                     /locus_tag="LP245_000735"
     CDS             18111..19301
                     /locus_tag="LP245_000735"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBL1518672.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19403..20356
                     /locus_tag="LP245_000736"
     CDS             19403..20356
                     /locus_tag="LP245_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBL1518673.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20425..21774
                     /locus_tag="LP245_000737"
     CDS             20425..21774
                     /locus_tag="LP245_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1518674.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21957..22280)
                     /locus_tag="LP245_000738"
     CDS             complement(21957..22280)
                     /locus_tag="LP245_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518675.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22409..23572
                     /locus_tag="LP245_000739"
     CDS             22409..23572
                     /locus_tag="LP245_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBL1518676.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23642..24991
                     /locus_tag="LP245_000740"
     CDS             23642..24991
                     /locus_tag="LP245_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL1518677.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(25036..25467)
                     /locus_tag="LP245_000741"
     CDS             complement(25036..25467)
                     /locus_tag="LP245_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1518678.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25855..28497
                     /gene="alaS"
                     /locus_tag="LP245_000742"
     CDS             25855..28497
                     /gene="alaS"
                     /locus_tag="LP245_000742"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBL1518679.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28697..29293
                     /locus_tag="LP245_000743"
     CDS             28697..29293
                     /locus_tag="LP245_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL1518680.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29415..30563
                     /locus_tag="LP245_000744"
     CDS             29415..30563
                     /locus_tag="LP245_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL1518681.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30601..31014)
                     /locus_tag="LP245_000745"
     CDS             complement(30601..31014)
                     /locus_tag="LP245_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBL1518682.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            31093..31524
                     /locus_tag="LP245_000746"
     CDS             31093..31524
                     /locus_tag="LP245_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBL1518683.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31623..31856)
                     /locus_tag="LP245_000747"
     CDS             complement(31623..31856)
                     /locus_tag="LP245_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBL1518684.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            32039..33709
                     /locus_tag="LP245_000748"
     CDS             32039..33709
                     /locus_tag="LP245_000748"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBL1518685.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33856..34242
                     /locus_tag="LP245_000749"
     CDS             33856..34242
                     /locus_tag="LP245_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518686.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34229..34927
                     /locus_tag="LP245_000750"
     CDS             34229..34927
                     /locus_tag="LP245_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL1518687.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34932..35396
                     /locus_tag="LP245_000751"
     CDS             34932..35396
                     /locus_tag="LP245_000751"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBL1518688.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35393..36304
                     /locus_tag="LP245_000752"
     CDS             35393..36304
                     /locus_tag="LP245_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL1518689.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36539..37078
                     /gene="pyrR"
                     /locus_tag="LP245_000753"
     CDS             36539..37078
                     /gene="pyrR"
                     /locus_tag="LP245_000753"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBL1518690.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            37092..38375
                     /locus_tag="LP245_000754"
     CDS             37092..38375
                     /locus_tag="LP245_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBL1518691.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38388..39314
                     /locus_tag="LP245_000755"
     CDS             38388..39314
                     /locus_tag="LP245_000755"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBL1518692.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39333..40613
                     /locus_tag="LP245_000756"
     CDS             39333..40613
                     /locus_tag="LP245_000756"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBL1518693.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40618..41694
                     /gene="carA"
                     /locus_tag="LP245_000757"
     CDS             40618..41694
                     /gene="carA"
                     /locus_tag="LP245_000757"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBL1518694.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41699..44884
                     /gene="carB"
                     /locus_tag="LP245_000758"
     CDS             41699..44884
                     /gene="carB"
                     /locus_tag="LP245_000758"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBL1518695.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44938..45714
                     /locus_tag="LP245_000759"
     CDS             44938..45714
                     /locus_tag="LP245_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBL1518696.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45711..46643
                     /locus_tag="LP245_000760"
     CDS             45711..46643
                     /locus_tag="LP245_000760"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBL1518697.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46640..47356
                     /gene="pyrF"
                     /locus_tag="LP245_000761"
     CDS             46640..47356
                     /gene="pyrF"
                     /locus_tag="LP245_000761"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBL1518698.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47363..47992
                     /locus_tag="LP245_000762"
     CDS             47363..47992
                     /locus_tag="LP245_000762"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBL1518699.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47980..48294
                     /locus_tag="LP245_000763"
     CDS             47980..48294
                     /locus_tag="LP245_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518700.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48332..48973
                     /locus_tag="LP245_000764"
     CDS             48332..48973
                     /locus_tag="LP245_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1518701.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            49016..49708
                     /locus_tag="LP245_000765"
     CDS             49016..49708
                     /locus_tag="LP245_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBL1518702.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49705..50607
                     /locus_tag="LP245_000766"
     CDS             49705..50607
                     /locus_tag="LP245_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1518703.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50765..52471)
                     /gene="efbA"
                     /locus_tag="LP245_000767"
     CDS             complement(50765..52471)
                     /gene="efbA"
                     /locus_tag="LP245_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBL1518704.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        17215 a         9161 c        11301 g        14949 t
ORIGIN      
        1 ttaaaagtat aatttaatta attaagtttg ttttaagaag agaacttttt attaagtttt
       61 tttattttga ggaggaattt gaatgcaaga gctgaagacc cgcagtgccc ggcaccatag
      121 acctaaaaga aaaatggtga tcaataaaaa agcgattgct cctttaattg gaacgagtct
      181 tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag atgaacaagg
      241 atctcaaaca gtcgctgatc ctcaagcgtt tatcgatcaa atcggctggt ctgcgtcaga
      301 agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt tgttggaaag
      361 tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg gtgtgaaagg
      421 aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaaacg gacaatgggt
      481 aacgatgaat gagccattcc gaaaatattc ttcttattgg gaatccttcc aagaccatgc
      541 gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg gcgtgtggaa
      601 aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt atgctaccga
      661 tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa cccgttttga
      721 tacgccatca acaggttcgg ctacaacaat cacaagtaca acaacaacga ctactacgac
      781 gacttcaacg tcatcatctt caacaacaga tgtaaataca aataatggtc agacatatac
      841 agtcgtgtca ggtgatacgc tatgggatat tgcacaaaaa tttggcatgt ctgttgatga
      901 tctaatggcg aaaaatggca tgtctatgtc cagttattct ttattagttg gtcaagaact
      961 aaacgtttga tttagataaa aaggcaaaga aattaccata tatggtatat ctttgtcttt
     1021 tttttgctag tcaaagacga atcactcgcc ataaatgaac agattgtatt atgataagta
     1081 agaagagcaa agacaaggag gaattgaaga tgacagctat ctataactca gtcaccgaat
     1141 tgattggcaa aacgccaatc gtcaaattaa ataaaatcgt accagaagat tcagcagatg
     1201 tttttgtaaa gcttgagttt tttaatccag gaggaagtgt aaaagatcgt attgctttaa
     1261 gtatgataga aaaagcagaa cacgatggtc tactgaaacc aggtgatact atcattgaac
     1321 ctacttctgg aaatacagga atcggattgt cgatggtagg agttgcaaaa ggatataaag
     1381 taatcatcgt gatgcctgag acgatgagta tcgaaagacg tttattgatg aaagggtacg
     1441 gcgcagagtt gattttgact cctggtgcgg atggtatttc tggatcaatc agagaagcag
     1501 aacgtttggc aaaagaaaac ggctactttt taccattaca atttgaaaat gaagcaaatc
     1561 ctcttgtgca tgagaagacg actggtcctg agatacatca agcatttgga gtaaatggct
     1621 tggacgcgtt tgttgcaggt atcggtacag gaggaacgat cactggcgct ggccgagaat
     1681 taaaacgtgt gtatccgaaa atcgaattaa tcggggtaga accagcagaa tctgctattt
     1741 tagaagggaa agaagcggga cctcacaaaa tccaaggaat cggtacaggt tttgttccta
     1801 aaacactgga tacttctgtg tatgataaag tcctttctat tagtggagac gaagcgatgg
     1861 aaacagctag agaagttggg cgaaaagaag ggattttagt aggcatctca tctggcgctg
     1921 caattgctgc cgcgctaaaa gtcgcaaaag aattaggaaa aggcaagaag gtattagctg
     1981 tggttcccga caatggtgaa cgttatttat ctacagccct ttaccaagag atataaggca
     2041 cttggttttt ctccagatag gtttatgtaa aaaactttta aagatgaaaa gaacacacaa
     2101 aaatttatga tgagaaaaat tatttgaata gagacgtaga atagtgaacg cgactgtttt
     2161 acgtcttttt tcattaaaat acaataaaat tgaattttct tttcatgtta agtggatttt
     2221 aaaatgtaaa aatagtatga taagacgaga ataacaacgt ggggtgttta catggaaaat
     2281 aagttagtcg aagaggttat cgaaaagtta aaaaaagaga acattcgaat cacacctcaa
     2341 cggtacgcgg ttttagaata tttgattgaa catcattccc atccaacggc tgatgagatt
     2401 tataaagcac ttgaacatcg gtttccaaat atgagtgttg cgactgttta caataacctt
     2461 cgcttattta cttcgattgg atttgttcaa gaaatgaagt acggcgatgc ttctagccga
     2521 tttgatttca gttcaaagcg tcattatcat gtaatttgtg aaaactgcgg taagattgtt
     2581 gattttcatt acccagggct tgaagatata gaaatggctg caagcagact gactgatttt
     2641 gagattaatg aacatcggtt ggaattgtat ggactctgtc cggattgtaa agagtcagca
     2701 aaaaaggcgc aaatgtaaaa acagtttcta caagtgttat acctaaaaaa agctagctgt
     2761 gtaaaaaaaa cgctagcttt tttatttttt tgtcttttat tcacaatctt agatataaaa
     2821 gtgaatatta ttaaaataag aatcttgtag atattgggtt cttatgcttg aaaaggaatg
     2881 aaactacaaa caaacctttg tgaattcaca agcattaaac tgttgtatcc gttttatttc
     2941 tgttatagta gttttgtcga aggacaaaat gttaatcgga gggaccataa atgaaagtag
     3001 tagtaattgg ctgtactcat gcaggtactg cagctgtaaa aagtatttta aaaaatcatc
     3061 cagaagcaga agtgacagta tatgaaagaa atgacaatat ttctttctta tcttgcggta
     3121 tcgcacttta tgtcggcgga gtagtaaagg acccagcagg cttgttctac tcaaatcctg
     3181 aagaattatc ttcattagga gcaacagtta aaatggaaca cgatgtaaca gacgtcgata
     3241 cagaaaataa aacagtaacg gcaaaagatc tgaaaacagg agaaacagaa acggtttctt
     3301 atgataaatt agtgatgaca actggttcat ggcctattat cccaccgatt agtggaatcg
     3361 atgcgaaaaa tgtactccta tgcaaaaact acaatcaagc aaatgaaatt attgcacaag
     3421 cgaaagaagc aaaacgtgta gtaattgttg gtggtggata tatcggtatt gaattagtag
     3481 aagcttttgt cgaatctgga aaacaagtga cattgattga tggattagat cgcatcttga
     3541 ataaatatct agataaacca ttcacagata tcttagaaaa agaattgaca gaccgcggtg
     3601 ttactcttgc gctaggcgaa aatgttactg aatttatcac agatgaagaa ggaaaagtga
     3661 aacaagtagc tacaccaaca gatacatttg atacagatat ggtcatttta tgtgtgggct
     3721 tccgtccaaa tacaaaactg atcgaaggaa aagtagatac actgccaaac ggggcaatca
     3781 aagtgaatga atacatgcag acaagtaatc cagacatttt tgcagctgga gactctgcag
     3841 tagtcaacta caatccaagt ggcacgcaaa actatattcc tttggcaaca aatgccgttc
     3901 gtcaaggttt gcttgtggga aataacttga cagatcataa aatggcgtat cgtggtactc
     3961 aaggaacttc aggactttac ctatttggct ggacgatcgg ttcgacaggt gtgaccaaag
     4021 aaagcgcaac tttgaacgat ctagaagtcc aagcgactgt atttgaagat aattatcgtc
     4081 cagagttcat gccaactact gaaaaagtaa tgatggagct agtctatgaa aaaggaacga
     4141 atcgtatcgt aggtgctcag ttcatgtcca aatacgacat tacacaatca gcaaatacca
     4201 tgtctttagc tgttcaaaat aaaatgactg tagaagatct cgcactttca gatttcttct
     4261 tccaaccaca ttttgaccgc ccatggaatt acttgaacct acttgcacaa gcagcgctag
     4321 gcgaaatcga aactgcacaa taaagaaaaa gggttgtgac acaattttgt cacgaccctc
     4381 tgtctttttt tgtgaaaagt acaattagtt gtctttcttc gaattttttg tcacaataag
     4441 cagcaaagat aaagctgtta cataaaagaa caagcagctt tatttgattt tgaaaagaaa
     4501 ggtgagaaag aagatgaata aagaatattt tgtccaacaa gatgcatttt tagaagatta
     4561 taaaagtgct tcgaagaaat taacgatcaa tattgatgag ttggcagatc aagtactctc
     4621 tcagttgaat gaaacgcaag aggaatatta cacgatgcca gcaaatgacg ccaaagataa
     4681 tgtttctcat cgttttcctt tcagtagacg catctactca gatgaaaatg acggcacatt
     4741 gaatacagag tacacatatg aaggtcagcc atatgtgcta gaaactgatg atgatcttta
     4801 aagacagttt ttgaaaaggc cgctcatcct taagtgatga caaaaaatca tcacaattac
     4861 cgatgactgt ctctttacta tcttttaatc agaaaaaggg gttatgacaa gctttgtcaa
     4921 cccctttttt tcttggtttc agattgggtt ttcctacaaa atatttttat ctttgttgaa
     4981 taggaaacaa aaaaacaata taatgaaaga aaaagaaggt gtagaaatgg ataaaagaca
     5041 actgctaata gaagaatatc tggatttagc taatgagatt attcatcgta ataaaccaga
     5101 aatggaaaaa gaatttgcag gatttactct aaatgaacta gaagtgattg aacatatcgg
     5161 gaaaatccct gatcctaacg tgacaaaatt agcgaatgct agttacatga ctagaggagc
     5221 catcagtaag ctaacaaaaa aactgatagc tagagggatc ataaacactt atcaaagcga
     5281 agagaataaa aaagaaatct attttcaatt gacgccaatc ggacaaaaaa taaggaatag
     5341 acacgagcaa ctccatcaaa aatgggtaca gcgagatgct actgtatttg aaaatatgtc
     5401 aaaagaagaa tttgacacag tatttcgttt tatcggtcga tacagagaat ttatacgaag
     5461 tagcaaatga agctactatt ttttattgta gtgataatag gcaaaaatca taagcaaaaa
     5521 tccgaatacc gtcggaagaa atggtgctgc agcataaagc tgtcctgcga ttagcgggcc
     5581 gatgacgcgc gatagagatt gtatactttg ggtaccgccc attacaagac cttgctggtt
     5641 atctgagaca gaattggata gttggccatt gaatacagga gtaaaaatag aatcaccgaa
     5701 accataacag ataatcccaa ataaaaacaa aatcggcagt agaagaattc cagataatgt
     5761 gatgaataga taggcgagga tttcactgaa catccctatt cttgtgatct gctgttctga
     5821 aaattttttg agcaatcgag gcataatgaa caattgcgag acagtatcca agattccaat
     5881 caaagagaag cttaaaccaa ccaacccagc cttccactga aaggcgtcaa tcgaaaattg
     5941 agaaaagata gattgaagag agccagctgc caaccaaaca gcaaaacctg ctgtcaataa
     6001 aggaataacg gatgaaatct tgaataattg ttgtaattgg tgaaaaggtc ttacatggga
     6061 gaaacttaaa tctactgaac gtttttttat tggaaggctt tctagcataa atgtgtagcc
     6121 ataaacggca tttaagaaag taaagagtgc tccaataaat ataggaacag aattccccaa
     6181 ctcagctaat agacccccta taataggacc cagcgttgtt cctataccga ctaaagcacc
     6241 catccatcca aaaactttgg ttctttcatt aggttccgtg atgtcggcaa agtaagcata
     6301 taaggtggag atttctcctg ccgtcaatcc ttcaatgata cgaccaagga acaacatcca
     6361 tatcgaattt cctaaaccaa aaagcaaata tccgatactt gatcctaata aactgataat
     6421 aaggatcgga tgacgcccaa aatgatcact taagctaccg agaatggggg cagataagaa
     6481 ggcagctaga gcataaacag acatgagcaa agtgatatag aaagcttgct gatgtatgga
     6541 gtgagaataa ggcagcgtta aaaacggaag tacaggactg acgatagtaa atcctaatcc
     6601 agtgaataag acagagacgt atccaaaaac tttagaatgt ttatttgtga aactgtacat
     6661 gtaaaaactc ctttatgcaa taatgttaac ttggaaacaa aaatagtgta tagtaatttt
     6721 gtttccttgt caacattcta aggaacagcg aaatctactt aatttattta ttccgaaaag
     6781 tgaagatacg catcaaaaac atgaacaaac aaaaatcaag tagacgacat tgtaaatctg
     6841 accgatcagt gaagtaaata gaaaagaaac ctgttcttgc ttcccatgtt ttttttacgt
     6901 atactgtgat tgagcggagg agaaatcatg ttgaatttag aaaattactt aagcgctgga
     6961 caaacagtca tatctaatct tttacttaaa aattatcata ggatcggtct acaatctgaa
     7021 gaatttttat ttgttctaca gttgcatatg gcacagcttg aaggagatac tttccctgat
     7081 ttgcagatga ttgctatgga tatgggaatc aaacaagatc agatttttca aatactggat
     7141 cgtctcgtaa caaatggatt tatcaagata gaaacgacga ttgtcaacgg taaaaaagca
     7201 gatcgatata atctttaccc catctatgat ctattaggtg agtatttaaa aacacaagaa
     7261 aaaaaatacg aagaaaaaac acaagaaaaa gaaatccagt cagtgtatca attatttgaa
     7321 caagaatttg gacgcccgct ttcttcgatc gagttccagc ggatcggaca atggctagaa
     7381 gaagaccatt atcagccgga aattttgaag ctagcactgc gggaagccgt attaaatcag
     7441 gcttatagtt ttaattacgt tgaccgcatt ttgctatcgt gggaaagaaa aaatctacgt
     7501 acaaaacaac aagtggaaga agaccaaaaa cgaagaaaac agcagcttct tcaaagagaa
     7561 gtagaacagt cagctcaaca agaagaattg ccgaaagtct cactgaaaaa ttggttggag
     7621 gagtagcgga atatgttaag caaacaaaaa acaatggaag ctctagaaac gatgtatgga
     7681 atgtttcccg aagcacatgg agaactcaag cacaataatc catttgagtt attgattgca
     7741 gtgatcttaa gtgcccaggc gacagatgta tcagtgaata aagcaacgcc agatttgttt
     7801 gcctcttttc cgacacccga tgcgttagca gaagcttcaa tcgatgaaat cattcttaaa
     7861 ataaaaacga ttggtttgta tcgaaataaa gcaaaaaaca tcaaagcgtg tgcacagcag
     7921 ctgattgaac gtttcgatgg gcaagtgcca acgtcaagag aagaattgat gtctcttcct
     7981 ggtgtaggca gaaagacagc aaatgtcgta ttgggggatg cattcgggat accagcaatc
     8041 gcagtagata cccacgtgga acgtgtctca aaacgcctga ggatctgcaa actagatgct
     8101 acggtcatgg aagtagaaga aacactgatg cggaaagtac cacaagaatt atgggtaaag
     8161 acacatcata cactgatttt ttttggtaga tatcattgca cggcaagaaa tcccaagtgc
     8221 gaggtatgtc ctttgctatc aatatgtcaa gatgggaaaa atcggatgcg tctaaaagaa
     8281 aaggcgctaa aaaagaaacc acgcctgtag acgtggtttc tttaattgca aataaatgta
     8341 tgaattatct tgttattatg gagaaaagct gtttcgttta tcttttttgc atgaaaaagt
     8401 aaatgtacat actcagtagc taggatggta acttattaca atttattgcg ataaaaataa
     8461 aagttgttat ttttattggg aaaatacccg atgtagaaaa taatgccttc caatatacct
     8521 ataaaataag tccagtattc caaaggatta tataaataag tgacgtatct atctaaaggt
     8581 gtaataaaaa tgataagtga taataaaaaa ataccattta taactaaaca taaactaatg
     8641 gatttgggcg gtttcaggct catcagaaaa atatagattc tggtgaacaa caaccataaa
     8701 aaagtgagaa tcattgcatg agagcttctt tccataaatt ttcctttaag agtagtgctt
     8761 aaaagtacag aaaaaataat aaatgcaagg ataggagcaa ttaaagtaaa tttatttaat
     8821 aataaacaaa atttttcagc ttttttattc ttggaataac gaggtattgt tttcgataaa
     8881 aaaagatggt gcagacaaat tatgataatt aagcatacta tcagataact caaaatgaag
     8941 ccttctttca aaaaattatt caaaaccata tattgtattt tttatttgat aataacaatg
     9001 ggattattaa gaagtggcac taaataaaag actagtgtgt atttagccga tttaattata
     9061 aacaagtaaa tggataaagt atatgtaatg ataaaagaaa aatggatttt ctaattttta
     9121 agctaaatgt tagatcacac atgtatatgc tggatagtct tataaaaaat catgtaatac
     9181 agcttggtac atgattttta tttgtagctg ttttttacat agacacaaaa aagaaaccac
     9241 gcttgtagac gtggtttctt ttttactatc tgtttccaga agctgaggtg ctgctggatg
     9301 gtgtatggtc atttgcagca tccgctccgc tagttgctgg ctcactggaa gaagcaggag
     9361 gagcagatga agacggtgtc gagctttctt cggatgaaga agaaggaacc gttgttgaag
     9421 acgctggctc gcttgtttct gctgtcgtgc tttcttttga ggactcagca gttgattcgc
     9481 tttgactagt agagctagag ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct
     9541 ggacatagct ggaagatgga atagttgttg atggtgtaat tgcattcgat ctagctgtat
     9601 attgatcttt gtagtacagt tcaccgccca cacgaattaa tccgcttggc atctcccagt
     9661 ctgtatttgt cacgttagct gaaacatact gcataagctc gcgataaaca tcagaggcta
     9721 cgtgtgacga ttctgaagtg acaggtgtca tttttttatt gtaacctgtc cacacggaaa
     9781 tcgaataatt tggcgtatag cccgcaaata ggatatctgg atacacccca gaagaaatac
     9841 caagttttgc atactcgtca tctgtgtaat tggatgttcc ggtcttaccg gcttgatata
     9901 acccagcgat ttgcgcattc gtaccagttc cttcagtgat cgtatctttt aaaatgtctg
     9961 tgatcatata agctgtttct ggagacatgg ctgtttttcc atctggctca taagtttctt
    10021 ctgttccgtc ttggaagacg attttattaa catattgagg tttgtaataa gtccctccat
    10081 tggcgaaagc cgcataggct gctgccattt ttaaggaaga agctccgtat tttgtcccat
    10141 cttgttcttc cgtattacta gagatcgcat tcgattgatg gatcgtactg tattcgatcc
    10201 caagattttt taagaaagaa gccactttat ctgaaccgac ttcattgaat aatttgactg
    10261 ctggaacatt acgggataag taaagtgctt ggcgtaaagt aatggtgccc atatattgat
    10321 tatcccagtt tcctacagga gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag
    10381 tttttccagt agaatatttc aaatattcaa aagctggtcc gtaatctgtg acaggtttca
    10441 tcgtagaacc aaaatcacgg gaagtattca ctgctaagtt gttgcctaaa gttacgtctt
    10501 ctgcgatgtg acgtccgcca atctgggctt ttactttccc ggtattggtg tcgataaggg
    10561 tggaggcaac ttgcatctcg tcgtctgggt aagagacata ctgatccgtg ttgacgatat
    10621 catatagttt cttttgggcg tccagatcca aattcgtata aatctctaaa ccgtctgtgt
    10681 agacattctt atctgttttt tcttgtactt cattgatgac ttctttgaca taattatcga
    10741 cgatcttagt attgtcatcg gattgagtta gttcttgcag accatccgtt accggtacat
    10801 taacagcttg atcatattct gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa
    10861 cagtatctcg tcttttcttc gcctgatctg gataaacata aggatcatag gcggaagggg
    10921 cttgaggcat cccagcaagc aatgctgttt gcggtaaaga aagttctgat aatttcttac
    10981 caaagtacat ctcagaagct gtctccatcc cgtacaagcc gtttgacata tacactttat
    11041 ttacgtagta ggtcaagatc tcttgtttcg attttttttg ttccaatctt acagccatcc
    11101 acgcttcttg ggccttgcgt ttcagagtct gatcctcggc actggtggag aagaaggaaa
    11161 gtttgatcaa ttgctgtgtc aaagtacttc cgccttgcag tccgccagag gtaaagttag
    11221 agagggcaga accgatgatc cgaatagggt caaccccgat gtgtttataa aaacggcgat
    11281 cttctaccga cacgatcgca tcttctaatg ttttcggtaa ttcattcgca gaaatttttt
    11341 cacgcttttc tgcgcctaaa tcttcgaata gttcgccatc ttgtgtatat agtttggaag
    11401 atacggtagc gtctaatttt ttatccgtca attcgggcgc atcttttgcg taataccaga
    11461 aaagtcctac acctgctaaa aagaggatac agaaaaatga gagtattcct aaaaggatct
    11521 tgataaataa tcctttttta tgtgttccag aggactttcc agaacctttg ccagaattct
    11581 tcttcacact ctttttagga gtaggctgtt tctgtcgtct agagcttcta gtttgttcat
    11641 ttgccattct tgctttctcc ttcaatagat aatgttgata aatagaagtc aaccgcgtcc
    11701 aaataaggaa tccgcggaga aataccagtt ttgatctcta ttcctagttc ttcgatcaaa
    11761 gataaaggta gtgatttgcg tcctttttcc ttttgggcgt cccagtaagc aatcaaatga
    11821 acactattca aataaaaaca gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc
    11881 ccattttgtt cgaggcatgc tttcatatgt tcgatttgat gggcatggaa gtttttaaag
    11941 ggaaaagatg ttttgttctt ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag
    12001 acgccattat agtctgtagt tgaggcttgg gtaaagtagg cttccttgat cacagcagca
    12061 cttctcttag gatagtctac tttcacgatt tggatagggg taggcttttt atggataacc
    12121 gccaacccgc gggaaagata atatttatta ctttcattga ttgcttcttc aaagcgcatc
    12181 ccccgattgc cgaattcagt gatctgattt cttttttctt gaattttttc gacgggagag
    12241 gcattcttat aataaggttg gccatttgga tagcgcaata ccatctttaa tcacactcct
    12301 aggccacatt atagcaaaaa agcggataga aagaaaagga atctgagatg gataagtcaa
    12361 aagtaatcta tgtgtctggg tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc
    12421 ctaaaatcca agttgttaaa aatgttttaa aaaaagaact ccatcagtta gcagaagaag
    12481 ggctggaatg ggtacttgtc agtgggaatt tgggcgtcga actatgggct gtgcaaatag
    12541 tagcggaatt gaaagaagaa tatccggaac tatctcttgg tattttgtat cctttttctg
    12601 attttggtaa taactggaat gaagggaacc aagaaaaaaa acaattagca gaacaattag
    12661 cagattatgt cgaagctgtt agccatcaac cctaccaatc acctagtcag ctaaagaatc
    12721 acactcgttt tatacttgag catacagtgg gctgtctgct gatctatgat gaagaattcc
    12781 ctggaaaaac gaagtatttt tttgaagatg cacagaatta ccaagcagat catccctacg
    12841 aaattcggct gatcagtatg gacgatcttc aaaattttag tgaataatcg atattgtgtt
    12901 tgatttatca acttttttcc tatacaatga aaaaggtaga aatgttatta cgtaaatgaa
    12961 aactagaggt gtaaatatgg cgaatttggt ttatagtcct aaagacattt tacaacaaga
    13021 attcaaaaca aaaatgcgcg gctatgatcc cgttgaagtt gatgaattct tagacaatat
    13081 catcaaagat tatgaaactt acagcaaaga actccttgct ttacaagaag aaaacgatcg
    13141 attgagtgca aaagtagctc aattatctaa aactcaagga gcagctcaaa cacgcgtgca
    13201 acaaacagag gcaccaaaga gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc
    13261 aaatcttgaa cgtgaagtat ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc
    13321 agcacaacct aatccaaata actacacaaa tgcagacaca agcttagatg ataatgaaaa
    13381 aacacgtcaa ttttaatttt tgattaatga atttgcggtt ttcgggtaat cgcggtctga
    13441 cttgatcagg ctgaggaaag tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc
    13501 ttagcgaaac cataagctaa ggtactcttt ggagtaacgg caggaaaaca agctaaggct
    13561 tcggctatgc ttaagtatcc ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat
    13621 ccggtggaac gcggtaaacc cctcgagcga gcaacccaaa caatggtagg ggcgcttttt
    13681 gtctggaaga agaacaggac aaaaaggcag tataactgca gatagatggt taccgctttg
    13741 ttttttctcc ctggaaaagc aaagtacaga acatggctta tagaaaaccg caaacatcag
    13801 ggaattaggt cgtgacaaaa gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta
    13861 tttttcaata cttcagatga atcgttctta ttacaaaaca aacttttgta tcaccggtta
    13921 ttcggaattt gagtaaaagt gtggggtagg actgatgtcc cacctccttt ttttataaat
    13981 aaggagattg tgtatggaaa aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg
    14041 gctagaagca ctggttggta aagaattaag agatcttgga atcgaatgcc aagttgagaa
    14101 cggacgtgca cgttttgaag gaacaatgga aacgatcgct acagctaatt tatggttacg
    14161 tacagcagat cgagtaaaaa tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt
    14221 gtttgaaaac gtaaaagcat tgccttggga agattttctt ccactagatg cagcttttcc
    14281 tgtagctgga aaatcgatca agtcgaaact atatagcaca cctgattgcc aagcgatcac
    14341 aaaaaaagca atcgttgaac gtctccgtac ctattatcac cgtccagctt ctgtaccact
    14401 gacggaaact ggcgcacatt ttcagttgga agtagctttg ctgaaagacc atgtgatggt
    14461 aactctggat acgacaggac caagtttatt caaacgtggt tatcgcttag aaaaaggtgg
    14521 agcaccattg aaagaaaaca tggcagcagc acttattatg ttgacaaatt ggcgaaaaga
    14581 ccgtccattt tatgatcctg tatgtggttc aggtacgctt tgtattgaag cagccttaat
    14641 aggccataat atcgcaccag gattcaatcg tgagtttgct tgcgaatctt gggattggtt
    14701 cagtcaagaa atcatggaaa atgttcgatc agcagccgaa gaaaaagcag attatgatat
    14761 tgaattagat attactggtt cagatatcaa tggacggatg attgaaattg ccaaagccaa
    14821 tgcagaagaa atcggattag gctcttcgat tacctttaag caacaagcag tcaaagactt
    14881 caaaacggat aaagaatacg gggtcatcgt ggctaatccg ccttacggag aacgtctagg
    14941 agaagaagaa actgttcgga aattatataa agaaatgggc gatgtattcc gtccattaaa
    15001 aacatggagt aaatatatct tgactagcga cttagcgttt gaggaatttt acggacaaaa
    15061 agcaaccaaa aaaagaaaat tgtacaatgg tgcattgcgt acggatctat tccagtattg
    15121 gggaactcgt ccgcctagaa aaaaagagaa agacgaataa tcttactaat tgattcattc
    15181 aattggatgt ttggaggaat agggaatgaa agaaaaagag tttttacaag aagtaaaaga
    15241 aatcaatctt ctacaacaag ctttaggaat cctcgattgg gatacacaaa caggtatgcc
    15301 tgaaaaagct agtgcatacc gaagtgaagt agacagctat ctttacagca tttatttttc
    15361 aaaaaaaatc ggtccaaaaa tcaaagaagc cattcgctat ttttctgaac atccggaaga
    15421 attgtcggaa gttggaactg ccgtttttgc caaagtaaaa gaagagtatg atttggaaca
    15481 tcgcgtaccg gaagatctta tgagaaaata tacagctgcc gtttcttcag cacacggaca
    15541 atggcaaaaa gctagagaaa cacaacaatt ttctgatttt caacacgcat tgaatcaaaa
    15601 tattgaatta acaaaacagt tgatacctta ctggagaaaa gatgaaaaga cgaattatga
    15661 tgttttgctg aatcaatacg aacccgggat gactgtcgaa atccttgata aggtatttga
    15721 tcagcttaaa gaaggaattc tttcgatccg ccgtacgctc caagaaaaag ggactgaacc
    15781 tgaaacagac tttttaaatc ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa
    15841 agtaatcgaa caacttggtt atgattttag tcgtggtcgt ttagatgaca ctgtccaccc
    15901 atttatgact ggaattaatc cgaatgatgc acgaatcacg acacgatgga acgaaacaga
    15961 tttcaaaatg gctgtttttg gagtgatcca cgaggctggt catggtatgt atgaacaaga
    16021 catcgatgat aaatatgcgt atacaccggt ttatgaaggt acatcaatgg gtatccatga
    16081 atcacaatcg ttgtttaacg agatcattat tggaagtagt cgcagcttct ggaaaaagca
    16141 atatcctttc tttcaagaat gtgcagaagg aacattcgat gatattcctt ttgacaaatt
    16201 ttatcgttca ttgaaccata caaaatcaag tttggttcgt atcgaggcag acagtttgac
    16261 ttaccctctc catatcatca ttcgttatga aatcgaaaaa atgattttca atgaaggggt
    16321 agatgttgct gaactacctg aaatatggaa tcaaaaatat gaagagtatc tgggaatacg
    16381 accaacaaat gatgtggaag gcatcctaca agacgttcat tggtcaggtg caagctttgg
    16441 ttattttccc tcttatgcat tagggtacat gtatgcggca caattacttc attctttgca
    16501 gcaagaaata gatgtggaaa atgttctagc gtcagacgat tattctccaa tcaaaaactg
    16561 gatgtcagag catatccatc aatatggtgc atctagaaaa ccaaatcaat taatcatgga
    16621 tgcaacacat gaaccgctta atccgcaata cctgatcgac tatatgaaag acctgtattt
    16681 taatgtatat caggtaaaat aaaatacaat ttacaaagat agctgaaatt catctaatct
    16741 atagatgttt tcagctattt acttaagaaa gaagtggaac gaatggataa attacaagtg
    16801 atcgctgatt atagtatgga ccaattagcg catgatcaaa caggacatgg gagcgatcat
    16861 accaaaagag ttgtcaagtt agctgaaaaa attttggaga cggaaccgca ggcagaccgc
    16921 tttgtgacgc ttgcagcagc ttacctacat gatacgattg atgataaagt cgttaaaaat
    16981 gagaacgagg caaagcaaca gcttcgtgta ttccttcgct ctttgccaat agtagaggaa
    17041 cagatctcga tgattttttc cattatcgaa aatatgtcct tttctaaaaa tctctctgaa
    17101 gcggccgaac tatctctgga aggtaagatc gttcaagacg ctgatcgtat cgaagcatta
    17161 ggagcaatcg gcattttgcg tactgcttat ttcggcggtg gacatgggca cccgattttt
    17221 gatcctgaac tgtatccgca aacattcaag gacaaagaaa attaccgaaa aggcacgaca
    17281 gtgatcaatc atttttatga aaaactgttc ttgctgtctg ataaaatgaa tactgattac
    17341 ggatatgaag aagccaaacg aagagaaacc ttcatgcgtg aattcttaga agaatttttt
    17401 ctggaatggt ctattgacga tgaaaatttt actccagaca attggatcaa aaataacaaa
    17461 aaatgatgga ggttgtgaca gaagtggtca gctccaagat atttcggatc attttccgta
    17521 aaagttactt ctggaacact gtttaccaag aggtcgtgag cctgccgttc agctccgagt
    17581 cacaaggaac aatttcaaaa aatagcttct cgtgtttgat gaatattgta acttgtgatt
    17641 cggaattggc aggagaacac cgtttattcg gaagaatagg actgtgacaa gacttttgtc
    17701 acagtccttt tttcgaattc aacaagtaaa acttttaaga aatattcaga gagtaaaatt
    17761 aaaaattgct gataaacgaa gatggaaatt ttatgtattt ttattggtct atgcaataaa
    17821 taaattaaat attcagaata caattgattt taacgaaagg gcttctatca atggttgtgt
    17881 tgtatttatc tgcccaggta gagtaaaata gatcattatc taaaaggtaa ttgttcatac
    17941 tatataagtc atttgaaagt aaaaagatac tgtaaataaa aaatgtggtt aaataattct
    18001 cataatcagt gtaagcgtta tcaaaaatat agcatacttg ctttgtagat gaatgacacg
    18061 atatatgttt ggtatgttct gcaagacaga tgaatatgga ggtggagaca atgtcttcca
    18121 aagaactaac aatgtattta gagaaagaat tggatcaact gaaagaaaag gggttataca
    18181 atacgatcga catactagaa agtgaaaatg gtgcttgtat catcgtagac ggaaaaaaga
    18241 tgatcaatct agcatccaac aattatcttg gatttgccaa tcgcgaagaa ttgaaaaaag
    18301 catgtattga agcaaccgaa acttatggtg taggagcagg agcagtccga acgatcaatg
    18361 gttcgctgaa aatccatcag caattagaag aaaaaatcgc agaattcaaa gggacagaag
    18421 cagcaatcgc ctttcaatct ggattcaact gcaatatggg cgctatctct gcagtaatga
    18481 caaaagaaga tgctatctta tcggatgaat taaaccatgc atctattatt gacggttgcc
    18541 gcttatccgg agcaaaaatc atccgaatta aacatcaaga tatgaaagac cttgagaaaa
    18601 aagcaaagga agcgatagaa agtaagaaat ataaaaaaat catgtatatc acagatggtg
    18661 ttttctccat ggatggagac attgcacgat tgccggaaat tattccgatt gttgaaaaat
    18721 atggactgat cacctacgtc gatgatgcgc acggctcagg cgtaactgga aaaggtgcag
    18781 gaaccgtcaa gcattttgga ttaagcgaca aaatcgatat gcaaatgggc acgttatcga
    18841 aagctatagg tgttgttggg ggttatgtag ctggatcgaa aacactaatc gactggttga
    18901 aagctagaag tcggccattc ctattttcta cttcgctaac tccaggtgca gctgcagctg
    18961 cattggcttc gattactttg atgcaagaac atccggaact tgtcgaaaaa gtttgggaaa
    19021 atgctaatta ttttaaagaa gaattgaaaa aagtaggcta taacatcggt atgtctgaaa
    19081 cacctattac tccagtcatt ttgggagacg aaaaagtgac tcagactttc tctaagaagc
    19141 tgatcgaaca tgggatttat gctaaaccaa tcgtttatcc aactgtgcct cttgggacag
    19201 gcaggatcag aaatatgccg actgcggaac atacgaggga aatgcttgat gaagcagtag
    19261 cagtttatca aaaaatagga aaagaaatgg aaattattta actaaattta gttttttcgt
    19321 ctatttaaaa ttagagaaca tgttcacgca tatattgtta atcatctgaa gatagtagta
    19381 aaaaagatca gggaggatca tcatgaaaaa agtattggtg acaggatgtt taggacaaat
    19441 tggttcagag ttgatcacac ggctacgtca agaactaggc agtgaaaatg tcattgcgac
    19501 agatatacgc atgcctgaag tcattgagaa aaacgatatc tttgagatcc tagatgtaat
    19561 ggattacgaa aaaatgcgca gcatagcaga acaatatcaa gtggacacat tgattcattt
    19621 ggctgctctt ttgtcagctg ttgcagaagc aaaaccacaa ttagcctgga atttgaacgt
    19681 gactgggctg gtcaatgcat tggaagtcgc tagagaattc cagctgaaat tttttacgcc
    19741 aagttcaatc ggcgcgtttg gtccaaatac tccaaaagat cataccccac aagatactct
    19801 tcagcgtcct acaaccatgt atggggtaac gaaggtagct ggagaactac tatgtgatta
    19861 ttattatgtg aaatatggcg tagatactcg tggtgtccgt ttccctggat tgatttctta
    19921 tgcaaccttg ccaggaggcg gtacgacaga ctacgcagtc gatatttatt attcagcaat
    19981 caaagaagga aagtacacta gtttcattga tcaaggtaca tcaatggata tgatgtatat
    20041 gccagatgcg atcgatgcca ttataaaact catgaatgca gatcctgatc gattggttca
    20101 tcgaaatgcc ttcaatatat cggcgatgtc ttttgacccg gaagagatca aagcatctat
    20161 tcaaaaaatc ataccagatt ttgaaatgga ttatgatgtg gatcctgtac gtcagtcaat
    20221 agcagaatct tggccaaatt cactagatgt ttcttgtgcg caagaggaat ggggcttttc
    20281 gccgaaatac gacttagatg tgatgacaaa ggatatgttg gaaaaactga aagaaaaatt
    20341 ggtagagacg gtataaaaca agaaccacat ccaaaaagtt ttttatactt ttgggattgg
    20401 ctatggtatg aaaggggaca agggatggaa gaatatcaag ccacgccagt aaaagaagta
    20461 aaaatagaaa atgaattaaa acgtacgatg ggatttttta ctgctttatc gactgttatg
    20521 ggcacagtga tcggtgcagg ggtatttttt aaagccgcaa gcgtagcaga agttacagga
    20581 tccgccagtt tgcatatgtt ttcttggttt ctcggtggta tgatttctgt ctgtgcagga
    20641 ctaacaggag ctgaactggc agctgctatt ccagaaacag gagggatgat taaatatatc
    20701 gaacggattt acggaaatac agcagctttt ttattgggct gggcgcaagt cgtgatttat
    20761 tttccagcaa atgtagcagc cttgtcgatc attttcggta cacagttcgt caatctattt
    20821 ggtctttccc agtcaatgat tgttcccgta gctgttacag ctgctgtatc gatcctgttg
    20881 atcaattttt taggttctaa agctggaggg gcttttcagt cgattacgct tgtctgcaag
    20941 cttattcctt tgtttgtgat cgtcattttc ggtttgttcc gacaagaagg agtagacttc
    21001 caactgtttc cgatccaagc aggagaaaat ctttcatttt tctcagcctt gggagcgggc
    21061 ttgctagcaa cgatgttcgc atacgacggt tggatacacg taggaaatat ttcgggagaa
    21121 ttgaaaaagc cggcgaaaga tttgccaaaa gcaatttctt taggaatcat cggaatcatg
    21181 atcgtttatt tattagtaaa tgcggtgttc ttaagaaccg catctatcga cggagtcgca
    21241 ggaaacagca atgcggcaag tgacgttgca aaaatgattt ttggcggctt cggtggaaga
    21301 ctggtcacag ttggtatctt gatttctgtt tatggaacca tcaatggcta tacccttact
    21361 ggaatgcgtc tcccttatgt tatggcaaaa gaaaacaacc tgccttttag caagctcttt
    21421 gctaaacttc atgataaaac taaagttcct gtagccgcag gtatcttaga gctagtcatc
    21481 gctattggca tgatgatgat cggtggtttt gatacactaa cggatatgct gatctttgtc
    21541 atttggattt tttatacgat ggtctttgtt ggtgtcattc ttcttcgtaa aaaagaacct
    21601 gatttgtttc gaccatacaa agttccaatg tatccgttta ttccactagt agcaatcatt
    21661 ggagggactt ttatcgtatc aagcacgctt atcactcaga cctttttagc ttcgatgggg
    21721 atagtattga cacttgctgg tatcccgatt tatctctatt taaaacgtag atagctaaaa
    21781 cattcgaatt ttattagaac tgcacttctc tgccaaacaa aatattttat ttaaatgagg
    21841 agtacgtgga agaaatgtca aaagtactcg ttaattttga tcacgtaaat gtcgttttgt
    21901 ctacgatgaa atagcaaagt aaaagacaga aatcgggctc aaccgatttc tgtcttttac
    21961 tttgatttgc gtaactgaac tattcggcgt acgccgcgat aaatatttaa taaaaccaag
    22021 caaccagaaa tgaaaatggg aagccaaatc agatagacag ggtagccaag cactttagac
    22081 aaagcatgtg gagtcatttt atccatttca agaagtgctt gctgccaagt ctgaagattg
    22141 aagactagca tgaaacccga aataatcagg agaataaatc ctaaataatg aattgtagtt
    22201 ctttttctta cataagcgat cgtagcataa aggaacagta aaaaaatagg tacgccaaaa
    22261 acaaagtaca tattcagcat ctcgacaccc cctttgtgtt tatcttactt tactttgaaa
    22321 gaaatgagaa ataatagcct cgttacttgc ttgaaacagc aaaggactgc taagataaga
    22381 gagatacaaa gaatcaagga ggagtcatat ggcaagttat atcgaaccga ttcgttttgc
    22441 gctgattgtt tttccatttt tagccttagc gatctcatct gtttttttta tttatgaata
    22501 tcgaaagtat ggaacatttc tagtaacaag ggcagttatt ttgtattctt tcgtttttta
    22561 tttattgtgt gcgtattttt tggtgatctt accacttccg gcaaaggaga cggttgccca
    22621 aatgacaggg ccaaagatgg agctgcattt atttgcttca tggcaacatt tcagagacaa
    22681 cacggtattg gtcttgtctg aacctagtac ctacctgccg gcaatgaagc agagtgtatt
    22741 tttggaacca gcttttaatg ttttattact cataccattt ggcatttatt taagatatta
    22801 tttccggctt tcttttatga aaacgatgat tgctagtttc tgcctttctc tattttttga
    22861 attgacgcag ctaagtggac tttattttat ctacccaaga ccataccgct tatttgatgt
    22921 gaatgattta gtgacaaata cattgggtgg aatcattggt tttgtcgtta cgccgttatt
    22981 tacatttatg cttcctacaa gaagacgaat ggatgaactt tcttatgaaa aaggaaagac
    23041 tgtctcattg actcgacgct tggtcgctta tttgatcgac tggacatttt tatctcttat
    23101 taatttggta gcggcgattt tctttaaaat tgcgttcgat tcaggggcag ttacttctca
    23161 tatctggtgg cttttattag aagtaggggt atactttatg attgtaccgt ttataaccaa
    23221 tggatggaca cttggcaaaa aaattgtgcg tatccgtttg gtggaagaag accgcgaacg
    23281 aatttcttta aaagcattga tgatccgcta cgggtatctg tactttcttt tttatggttt
    23341 aagctggttg gggcagttgc ttcagcaaat catgaattcg acaacgaata cggtgttgca
    23401 gatgagtgca gtattcattt ctctcggtgt cttgttacta caaggtattt ttattttaaa
    23461 tatcttgcta tcatttttga gaaaaaaacg gattctgttt tatgaaaaag ctagtcacac
    23521 atatactgtt agcacgattg gccaaacaaa ggatgatgat tctcgaaatt agctgagcaa
    23581 aaacgctttg tctgtgttat aatgccaaag tcgtgataat ttaaagagaa gaggtgcacg
    23641 aatgaataat tttgatatat tccgcttcaa accgtttatc aatgaagcgt taaccgcaaa
    23701 gggcttcaaa cagcccacag aggtccagga acgtttgatt cctttaattg caaaaggaaa
    23761 aaatatcatt gggcaatctc aaactggtac aggaaaaaca catacgtttt tgttgccttt
    23821 gtttgaaaaa atcaatgcag aaaaagagga agtacaagtt gttattacag ctccaagtag
    23881 ggaactagct gcacagatct atgaagcagc tacacaaatc gctaaatttt ctacaccgga
    23941 gatccgtgtc tcgaattttg tcggcggtac agacaaacag cgtcaattaa atcgtctgca
    24001 tcaccaacag ccacaggttg tagtaggcac gcctggtaga atattagaca tgatgaatga
    24061 acaagcgctg aagattcaca ccgcatttgc atttgttgtc gatgaagcgg atatgacatt
    24121 ggatatgggt tttttaaatg aagtagacca aattgcaagt cgattaccag aaaagctgca
    24181 gtttttagtt ttttctgcca ctattccaga aaaacttcgt ccattcttac gaaaatacat
    24241 ggaaaatcca atcattgaag aaatcaaacc aaaagcagtt atttctgaag acattgaaaa
    24301 ttggctgatt tcaacaaaag gtaaagatga gaatcaaatg atttatcaac tgctgacaat
    24361 tggtcatcct tatttagcaa tcgtatttgc caatacaaaa cagcatgtgg atgaaattgc
    24421 cgattacttg aaaaaccaag gcttgaaagt agcaaagatt catggagaca tcaccccaag
    24481 agagagaaaa cgagtgatgc gacaagtaca gaatctggag tatcaatatg ttgtagcgac
    24541 tgatttagct gctagaggga tcgatatcga aggtgtctct catgttatta atgcagaaat
    24601 tccagaagat ctagacttct ttatccatcg tgtcggacgt actggacgta atggcttaaa
    24661 aggaacggcc attacgttat attcgccaaa tgatgagcaa gccattgatg cgatagaaaa
    24721 attgggcgtc tcatttgaac caaaagaaat caaaaacggg gaaatcgtca aaacatacga
    24781 tcgtaataga cgtgccaaac gagaaaaatc aaaagatgta ttagatccca cgctgattgg
    24841 tcttgtgaag aagaaaaaga aaaagatcaa gcctggttat aagaaaaaaa tcgattgggc
    24901 aattgcagaa aaaaataaaa aagaacgcaa aatcgaacgc agacagcaaa gccgtactgc
    24961 tcgtaaaaat aagaaaaatt cacataaata aaaaacaaga ggttgtgaca aaaggcgtgt
    25021 cacaatctct tgtttttaag ctagactttt tttcattccg atacaaagta cttcatcttc
    25081 aataaaaggt tctgtgcaag tatgataccc ttgtttttca taaaaatcta cagccgtcat
    25141 ttcagctact acataactag tctgacaacc ttctgaaacc gcccgttttt cagcagcttc
    25201 aagcaactga ccgcctaacc cttttcctcg gtattctttt gctacgcaaa atcgttccgg
    25261 cttgaagcaa gtaggtgttt tcttttcata acgcaaagta gctactggtc ttttttgatc
    25321 aagaaataga taataggttt gttgcgggat atcttttccg tcgaattcta gttctgcagg
    25381 aatcccttgt tctaatacaa aaacttgata tctcaaaaag cagctagctg cgcgtatcca
    25441 ttcatccgct ccaactattt ttttcatcat attcctcctt gtcatgaata gcagagatgt
    25501 attgattcct ttattcttat cgtaccaaaa atcgtggagt atgaccaaaa ggaaatgaaa
    25561 ataaaaattg agatattgac agtgatcaat agaatgcgta tactaaataa gtacgaaaag
    25621 gatatgattt gttttttaag actcacagaa aattctttct tggctgaaaa aagaatagtc
    25681 actaatcaaa ttgctccctt tttctatttt ggtagaaata ccgacgcagc tcagcgttat
    25741 cgagtttaag aggtaatgat tacacatcat tgcaatcaag gtggtaccgc gagttttcgt
    25801 ccttggctgt gatggtgttt ttttgtattt aatttataga aagcaggtaa tgacatgaaa
    25861 caattaagta gtgcacaagt tcgacaaatg tttcttgatt tcttccaatc taaaggacat
    25921 acgattgaac ctagtgcgtc tttgatcccc gtgaacgatc caaccttatt gtggatcaac
    25981 tctggtgttg caacattgaa aaaatatttt gatggttcag ttgtgccaga aaatccaaga
    26041 atcacaaatg cccaaaaatc tattcgaaca aatgatatcg aaaatgtcgg taaaacagca
    26101 cggcaccata cgatgtttga gatgctgggt aatttttcga ttggtgacta tttcaaaaat
    26161 gaagccatcc actgggcatg ggaatttttg actgatccaa aatggatggc attcgatcca
    26221 gaaaaacttt atgtaacagt ttatccaaaa gatacagaag caaaacgcat ctggcatgaa
    26281 gaagttggcc tgccactaga tcacattatt gatgtagaag acaacttctg ggatatcggt
    26341 gcaggcccat gtggtccgga tacggaaatt ttctatgacc gtggagaagc ttataacgat
    26401 ttagcagaag acgatcctga aaactatcca ggaggagaaa atgaacgtta tttagaaatc
    26461 tggaacttag tattttcaga attcaaccat aagcctgata acacatttga accacttcct
    26521 cataaaaaca ttgatacggg gatgggattg gaacgcatgg tctcaatcgt tcaagatgcg
    26581 tcaacgaact ttgagacaga cttgtttatg cctattatcc acgccgtaga aaagctaagc
    26641 aaacaagtaa aatatggtga aaacccagta acagatattt cttacaaagt aatcgcagat
    26701 catattcgcg ccctttcatt tgctattggc gacggtgcat tgccatcgaa tgaagggaga
    26761 gggtatgtct tacgccgttt gcttcgtcgt gctgtcatgc atgggaaaaa attaggtatt
    26821 gaacaagcat tcttatatcg tttagtccct gttgttgggg aaatcatggt aagttattat
    26881 cctgaagtac ttcaacaaaa agaatttatt gaaaaagtta tccgtacaga agaagaacgt
    26941 ttcaatgaaa caatcaatga aggtttggaa atcttaaatc aagtgatcca agaagtaaaa
    27001 aacgaaaacg ggacgactct agcaggaaaa gacatcttca aactatacga cacatatggc
    27061 ttcccggtag aattaacgga agaggtggca gaagatgaag gactgaaagt tgatcatgct
    27121 ggttttgaaa aagaaatgga tgcacaacgc gaacgtgctc gctctgcccg cagtactgaa
    27181 aaatcaatgg gggtacaatc tgctttattg acagatatca aagtagaaag taaattcatt
    27241 ggatacacag aacaagaatc agatagtcaa ttattggtca tcgttaaagg tgagtctctt
    27301 ttgaatgaag tcgcagaagg tgaagctcaa atgatctttg atcaaacacc tttctatgca
    27361 gaaatgggtg ggcaagtagc ggatcaagga tggatcatga atgaagtagg cgaaatcgta
    27421 gcagttgtta cagatgttca aaaagcgcct aatggtcaat ttatgcacac cgtagaagta
    27481 aaagcaccaa tgagtgaagg acaaacctat catctattga tcgatcaatc gatgcgcaat
    27541 cggatcatca aaaaccatac agcaacccat ctactgcaca aggcattgaa agaagtactt
    27601 ggcgagcatg caaatcaagc tggttcttta gtcgctcctg gacatttacg attcgacttt
    27661 acccactttg gtcaaatcac ttcagatgaa ttagctgaaa tggaaagaat cgtcaacgaa
    27721 aaaatctggg aagctatccc agttgaaaca attgaaacag atatcgatac agccaaaaac
    27781 atgggtgcaa tggctttgtt tggtgaaaaa tacggacatg acgttcgagt agtaaatatt
    27841 ggcggctggt caatcgaact gtgcggaggc acacatgtag caaatacaga aaacatcgga
    27901 atcttcaaaa tcgtttctga atcaggaatt ggtgcaggcg tgcgacgaat cgaggctgta
    27961 acaagtaaag aagcgtacga actacttgaa gaagaagaaa aacaactaaa acaagtagca
    28021 acaattgtta aatcacctca attgaaagaa gttgtttcaa aagcggaaca attgcaacag
    28081 caagtaagag agctacaaaa ggaaaatgaa caattagcta gcaagttagc gaatcaacaa
    28141 gctggtgatg tattcaaaga tccagaaacg atcaatggaa aaacaatcat tgcagcacaa
    28201 gtaaaagtga aagatatgaa tcagctgcgt caattagctg accaatggaa acaaaaaaat
    28261 atttcagata ttcttgtttt agcaaacgaa caagaaggaa aagtcagtct gctagcggca
    28321 atgacgaaag aatcaaatga agctggacta aaagctggcg acttgattaa agcaatcgca
    28381 ccgaaagtag gcggtggcgg tggtggacgt ccagacatgg cacaagctgg cgggaaaaat
    28441 cctgctggta ttccagatgc acttaaagct gcgaaagaat gggttgcgca acaatagggc
    28501 gtttacgttt gacagaaaaa caaaagttca aacattgaac gaaacatgat tatgggggcg
    28561 aagacaaaca agtcttgccc tcatactttt ttcaattgga tggcgcatct aatcaaatgg
    28621 tcggattcgg atggtcttta gttgacgaaa gtgacagaaa tttttacgat tagtataaat
    28681 aaaaaggggt gaaaaaatga atagtagaaa taagaccttt cgactagtct tacgtgcgat
    28741 cttgttagca atcatcatcg tacaagcgat ggttccttgg ctggggttta ttccattagg
    28801 attcattagt ttaacaatta tccatatcac agtaattatt gctgcagtag tattaggccc
    28861 aaaagatggc atggtgattg gcttgttttg gggaatcgct acaattgttc gtgcctatgc
    28921 catgccaaca acgccatttg atacattagt gttcacgaat ccgattatct cggtagttcc
    28981 cagagtactt gttggcttag tagcaggctt ggttttccac tggatttatc aaaaaaataa
    29041 atcaataacg atcagctcag cctttgcagg ggtactgggt tcattggtca atacagtctt
    29101 agtgttagga ttcatgggat tattttatac aggtgcaacg gcagatgcct atggtgtaga
    29161 ctctgctctt ttatttaaaa ccttagcagg ggttgcagca atcaatggga taccagaagc
    29221 aataggtgcg ggaatcataa caccattact agcaaaagcg ttatttgcag caacaccgtt
    29281 gaaaccagaa taatgaccat cttttaatag taataggacg cacgatagat agaaaaagga
    29341 agagaggaga ggaaaacaat cgtcctctcc atctttttac ctgagcaaca agcaaactag
    29401 aaggggtaaa aaacttggct aagaaacaag aagaaaaaaa gaaacaaata ccgcaacagc
    29461 ggacaaaaaa aggagtacta gcgggtatct taggattggt tacgaatctg atcttgtttg
    29521 tctctaagct aatgatcggg cttttttcag gaagtgtctc cattatggct gatgcagtga
    29581 acagtctatc agatactgct tcatccatat tgactttgat cggatttaaa attgctgcaa
    29641 agccagcaga tcaggaacat ccttatggac acgaacgctt cgaatatatc agtgggttat
    29701 ttgtttcgat catcattact tatgtaggat ttcaattttt agagtcttct gctgaaaaaa
    29761 tcatccatcc agaaaatgtc tctttaacac ccatcgtctt ttttgtccta atcatttcca
    29821 tctttttgaa atttgcacaa ggcaaaatgt atcaggttat tgcgcaatcc attgattctg
    29881 aaacattgag agctacagca acagatagtt ataatgatgt ctttactaca ctggctgtat
    29941 tgctttcagc agcaatcgaa tgggtaactg gatggcgtat tgatggatat ataggttttg
    30001 ctttagcatt atatatcctt tatagtggat tgacgatgct tcgaaatttt gtatacgaac
    30061 tattaggaag tcgcccaacg ccagcagaga ttgaagaaat ggaagagcat ttaaatgctt
    30121 gcgatgatat acttggctat catgatttat tggtgcataa ctatggaccc aataaacgct
    30181 ttgcatcagt ccacatcgaa gtagatgaat caatgaattt gaatgtggct cataagatta
    30241 ttgatctgat agaaaaagac tttaaaaagt ctttggatgt ggaacttgtc tgtcacttgg
    30301 atccaatgcc tgttgataac gaaaaatact ataatatctt gcggcagtta aagcaaattc
    30361 ttcttgaaac aggtacaggg cttaatattc atgattttag agtaattcat caaggaaaaa
    30421 cgctgcaatt tgatgtagtg gtccctgaga aattccagtt tgttgataca gaactagaaa
    30481 gaatcttacg tagtcaaata gaagaaaaaa tcggagatta ccaattggaa attacgtttg
    30541 atcacaatta tcttttatat taaatgagaa actataaaaa gactccttaa agtttttaat
    30601 ttaaagagtc tttttttctt ttaattgttt atggagagcc tgacgtgcaa gattatctgc
    30661 tcctttattt ttgttttcgg gcaaccattg caggatcaat aaagaaaatt cggatagaag
    30721 ttcttggatt ctttgaaggt agggaaggaa gagctcgttc ttcgttgcgt ttttgtcgac
    30781 cgtagaaact agtgttttgc tgtctgaaaa acagaaaatc gtttcattct gtaagtcgtt
    30841 tttctttaga aattctaaag tttttaaaaa gacttcgaac tctgcttgat ggtttgtccc
    30901 tatagaaagc gggatagata gctgttcttg tttaccttga tagacaatca agattccacc
    30961 tccactagga ccagggttgc cttttgtaga ggcatcaatg tatactttta acataaaaag
    31021 agattctcct ttttgttcaa actaatgtta tggtaagatt atatcattac tgaatcggtg
    31081 agaggttaga gaatgaaaaa aaatattcga tggcagcctg aactggcaca tacgatcatc
    31141 tattggtcat tgaccttgat cattctgttt tttagtctga ttctttcttt agaaaacaca
    31201 ggtccttatt ggaaaagcaa ttttgtttta ggtatttttc ttgtttttct atttctaggt
    31261 ttgcggcgtt cttttatttt aaaatcaaac tctgtgatta tacgttatgc tgctttttgg
    31321 aaagaccgag aaatatctgt cggacagatt cgatctttga cgccaactaa tactggggtg
    31381 caaatgatgt tgcaagatga gaaagcccca tctgttttca tgatgcgaaa aaaagatcaa
    31441 gtagtccttt ttgatcattt tgaaaaaaac ggacccaaat cagaatcaat tccttatcct
    31501 tatacgaaaa aaagaaaaag ctaattttaa aaatcagaac ctaaaaaaac gaatttttac
    31561 aggaaaagaa aagagtgaga cgtacggttc atcccgttta gcgtctcact ctatttgttt
    31621 atctattcat gcatactagt atcggtagtc tgaacgttgc ctttcttgac atgggcagct
    31681 tgtgttcctc gattcccttc gatgatctca aattcgacca cttgattttc ttccaaagtt
    31741 ttgaatccct cttcttcaat cgcagtaaaa tgtacaaaaa tttcttctgt gtcatcataa
    31801 ctgataaagc cgtatccttt tttgttgtca aaccatttta caattcctgt ggtcaaagca
    31861 ctcacgacct ttctaaagtc tgatcatagc cttcattata aagagtattt ataagtacgt
    31921 caaataaatt aaaaacctgt aattttatgt tttttttctg aataaaaaaa ggtataattg
    31981 gcatatctta acaaagaaga tattttgttg aataaagttc gtgaaaaggg gtaatcaaat
    32041 gaagaatgat ctgcaaattt cacaagaaac agagctagaa ccgattgttg aagtggctag
    32101 taaattagat cttaaggaag acgatttgga actgtatggg aaatataagg cgaaaatcaa
    32161 tttttctgga atcaatcgat caaaggataa cgctgagggg catttgatct tagttacttc
    32221 catcaatcca acaccagctg gcgaaggaaa gtcaacgatc actgtagggt taggagacgc
    32281 gctcaataaa atcaataaaa aatctgttat tgcattgcga gaaccctcac ttggtcctgt
    32341 gatgggaatc aaaggtggtg ctgcaggcgg aggatatgca caggtattgc ctatggaaga
    32401 tatcaacttg cattttactg gtgacatgca tgctatcaca acagctaata atgcattatc
    32461 tgctctttta gataatcata ttcatcaagg aaatgaattg aacatcgatg cccgccgagt
    32521 gatttggaaa cgggtagtcg atctcaatga tcgtgaactg cgtaaagtaa ttgttggctt
    32581 gggtgggcca atccaaggtg ttccaagaga agatgggttt gatatcacag ttgccagcga
    32641 aatcatggct atcttgtgtc ttgcggcaga ccttgaagat ttaaaggctc gtcttgcaag
    32701 gatcgttgtc ggctatacat ttgaccgtca gcctgtgact gctggagact tgaaagcaga
    32761 aggcgctctg gcattactgc tgaaagatgc aatcaagccg aatcttgtac aaacaattta
    32821 cggaacacca gcttttgtcc acgggggacc gtttgccaat atcgctcatg gctgcaatag
    32881 tattttagct accaagacag cattgagatt agcagattac gttgtcacag aggcaggatt
    32941 tggtgcagat cttggcggag agaaattttt agatatcaaa gtacctaact tgaaaaaagc
    33001 gccggatgct gtggtgattg tcgccactgt ccgtgcattg aaaatgcatg gcggaatgaa
    33061 aaaagatgaa cttaaaaatg agaatcttga tgctttgaaa gtaggttttg caaatttaaa
    33121 gcgccatata cgtaatatgg aacaatatca gctacctgtg atcgtcgcaa tcaatgaatt
    33181 cgtaacagat acagacaatg aactcacact gttggagcac ttgtgtgaaa atcaggggat
    33241 tcttgccaag agagcgagtg tatgggcaga tggagcagaa ggcggcgttg atttagcaaa
    33301 agctgtagta cgattgattg atagaaaaga agctaattac aagccattat accgcctaga
    33361 agaaacgata caagaaaaga cagaaacaat cgtcaagaaa atttacggag gaaatggtgt
    33421 tgttttcagc aaaaaagcgc aaaaacaaat agaagagttt acgaagaatg gatgggacaa
    33481 actgccgatt tgtatggcaa aaacacagta ttcattttct gatgatcctt cactgctagg
    33541 tgcaccggaa gatttcacca tcacgatccg cgaaatcatc ccaaaattag gggcaggatt
    33601 tttagtagcc ttgactggag atgttatgac gatgcctggt ttgcctaaaa aacctgctgc
    33661 attgaatatg gacgtgacaa atgacggaga agtgttggga ttgttttaag cttgattata
    33721 atctaccatc gaaggagctg tattttgact acagcttctt tttttagacg atagggaatt
    33781 aattttgttt acactaggat cattcttttt ctttattgta ttttgagcta tactaaagca
    33841 taataggagg gtatgatgaa aacgacattt ataagaaaaa ccggttttta cggtatgggt
    33901 agctcgattc agctaagaat caacaatgaa aaacgcagtg ttctcagtca tgaacaaaag
    33961 ataacgcttg atctggaagt gccctttacg atgcaggtca ccttttattg gctaaaaagc
    34021 cccgtttata cagtgaaaga agcaaagcct gcttatgtga tcacaatgaa ttacttgatt
    34081 cttcaaatct atccgttttt atttctagca actgggttgg gggccgtttt cctacaaaat
    34141 ttatttttca gtttttttgc agttattgtg ttgattgcgt tctttttcta tataaaaaac
    34201 cgggcatatt tgatcaagga ggaaaattat ggcaaactct gatctttttt taatcagttt
    34261 caatcgaatc gaaaaatgga tgagagacga gatgggaaat gcacgaaata tgggatttac
    34321 cgaacttgtc agacgcctag ctcaaagaaa acaattaatg atcagaaaat acgaagatga
    34381 tcttttacag cttgctcagt taaggaatgc gatcgtccat gatcggatcg cagtcgattt
    34441 tgtcattgca gagccaaatg attggacagt caagcgaatc cagctgatcg aacaagaact
    34501 gattcagcct gaaaccgtgc tgcctcgatt tgcaaaacgt gtaacaggtt ttgaacaaga
    34561 tcttccgtta cttgaactgt taaagatagt agcagaaaaa aggtattcac aatttccgtt
    34621 atacaataaa ggaaaatttg tagcattgat tactttacgt aatatcgggt tttggctagc
    34681 aaaagaaagc caaaaaggtc cggttgattt aacaaataaa cgagcgttgg atttgatcat
    34741 ccaaaacgga aagtacacaa attatcattt tgttccagct aaaacacata tttacgaggt
    34801 tgaagcgatg tttcgtgagc aagggacttt ggaagccgta cttatcacta aagatgggaa
    34861 tcccgatggt aatctgctcg ggatcgtacg acctcgtgat atttataaac aaatagaaaa
    34921 ggattgattt tttgttaatt atttattgga tattcagcgc tttgctagta ggagtggatc
    34981 agttggtcaa atggtggatc actgataatc tagcgcttgg agagacgaaa aatcttatac
    35041 caggtatttt gtcactgaat catattcgaa acactggagc cgcatggagt atgctagaag
    35101 ggaagatgtg gttctttact atagtgacac tcattgcagt cgttgtgatt ctcacattga
    35161 tgattaaaaa tcgtgaaaaa ggtaatcgct ggttcatgat tggattgagt ttgattctag
    35221 ctggtgcgat tggcaatttt atcgaccgta ttcgtcttgg ctatgtagta gatatgttcc
    35281 agacagattt tatgagcttt ccgattttta acgtagcaga tgtgacactt gtatgtggag
    35341 tgatttgtat gttaatttat attattttag atgaaaagga tcaaagaaaa aaatgacaga
    35401 acttaaaacg acgattcacc atgaatctgg taggatcgat aaagtattga ctaatttatt
    35461 caccgattac agtcgttcgc aaattcagct gtggctgaaa aatggagcgg tttctgtcaa
    35521 tggacagcca gtcaaagcaa attacaaagt aaaacaagga gacgagatta ctgtcttgat
    35581 ccccgaacca gaaacattag atgtggtccc agaaaatatc ccgttgacga tcgtttacga
    35641 agatgaagat gtagcggtga taaacaaacc tcaaggaatg gtcgttcatc cttcagcagg
    35701 tcatacgcat ggcacaatgg tcaatgcgct gatgtaccat atcaaggatc tttctacgat
    35761 caacggcgtt attcgtccag gtattgttca ccgaatcgac aaagatactt ccggactgct
    35821 aatggttgcc aaaaatgacc aggcacacga atcattagct cagcaattaa aagataagac
    35881 ctctttgcgc aaatatgttg ctttagtcca tggagagatt cctcacgaaa aaggaaccat
    35941 caatgcgcca atcggccgtt cgaaggaaaa ccggaaaatg caggcgataa gagaagatgg
    36001 gaagtcggct gtcacacatt ttactgtatt ggaacgtttc gaaggattta ctctggttga
    36061 attaaaacta gaaaccggaa gaacacacca gatccgtgtg catatgaagt atatcggtta
    36121 tccgttagct ggagatccag tatacggacc gaagaaaact ttgaaaggca atggtcagtt
    36181 tctccatgcg caaatgttag gttttacgca cccgactaca aacgaaaaga tgatctttga
    36241 agcacctctt ccagaagttt ttgaaaaaac tttagaaaaa ttaagaaaaa acattgcatt
    36301 ttaatttaga taacggtata gtaattaaca acgaaagcat aaaacttaat agaattcctt
    36361 taagtttagt cccgtgaggc taagaagggt gggagcaagg atacgtatgg tgcgccataa
    36421 gtagattgct cattgacata gtatagctat cagtgtatca gtatacgctc agtctaaaca
    36481 ttcctcctgt cctcttaggg caggagtttt tttatgcaaa aaagtagggg gaatgaaaat
    36541 gcaagcaaaa gaagtagtag atcaggtaac catgaagcga gcattgactc gaattactta
    36601 tgagattatc gagagaaacc atagtatcca agatatcgta ttggtaggta tcaaaacacg
    36661 aggaatctac attgcatcaa gaattgccga acgcctgaag cagctagaag atatcgatat
    36721 tcctgtagga gaactggata tcactttata ccgagatgac aaaaaagaaa atccagaaga
    36781 accggaactt cattcttctg acatcccagt ttccttagaa ggaaaagaag ttattttgat
    36841 tgatgatgtt ttgtatacag gacgaacgat tcgagcagca atggacgcag taatggattt
    36901 tggcagacca agaaaaattt cattagcagt cctggtcgat cgtgggcatc gagaattgcc
    36961 aatccgtgca gattatgttg ggaagaacat tccaacatct cgggcggaag agattttagt
    37021 agagatgcaa gagcttgatg gacaagatcg catcatgatt ttgaaagagg aagattagag
    37081 gagagagaaa catgtcggag aaaaaaggat ttcataatga tgacgtggtg ttagatatcc
    37141 acgatcgccc aaccccagga cattgggtag gattaagttt acaacacttg ttcacgatgt
    37201 tcggagcaac cgtgttagtc cccatcttag taggtatcga tccaggtatt gcgctagtca
    37261 gttcaggact aggtacattg gtgtacttat ttactactaa aggaaagata cctgcgtact
    37321 taggaagcag cttcgctttc attgcagcga tgcagctttt gatgaaaaca gatggttatc
    37381 cagcgattgc acaaggagca gtcacaactg gattagtcta tttgattgtt gcgctgatca
    37441 tcaaaaagat cggttcagca tggctggata aaatcttgcc tccaatcgtc gtcggtccag
    37501 tcatcatggt tatcgggttg ggacttgcgg caaatgcagc aacaaatgct atgtataatc
    37561 agggcacgta tgatttcaag tatattgctg tagcgctgat cacattagga ttaacaattt
    37621 tcttcaacat gtggctaaga ggttttctcg gattgattcc gattttacta ggtattatta
    37681 gcggatacat cgtagccttg ctgtttggaa tcgtggatac taagccaatc gtagacgctg
    37741 cctggtttgc tgttcctaac tttgagattc cctttgtaca atatgaacca aagctatatc
    37801 ttggagcaat cacaacaatg gcacccatcg cttttgtgac gatgacagag catatcggcc
    37861 atcttatggt attgaataaa ctaactaaac gtaatttctt tgaagaaccg ggtcttcata
    37921 agacgttgac aggtgatgga ttagcacaaa tcgtggcagc ctttgtcgga ggtcctcctg
    37981 taacaagtta cggtgaaaac attggtgttc tggctatcac acgtgtccat agcgtgtttg
    38041 tgatcggtgg agctgcagta tttgcagtca ttttaggatt cgtaggaaaa ttaagcgctt
    38101 tgattttaag tatccctgga ccagtcatct caggaatcag ttttatctta tttggagtaa
    38161 ttgccgcaag tggaatgaag attttaatcg agaacaaaat cgattttgat aaaaagaaaa
    38221 atctgttgat tgcttcagtt atcttagtag taggaattgg cggactcgtc tttgaagtag
    38281 gcacatttac attgtcggca atggcattag caactgtact tggcatcatt ttaaatctta
    38341 tcttaccaga aacttcacga agcgaagaaa actaaggagg aaacattatg atcatcaaat
    38401 cagaacgtat cagcttaaag catttattga ccgttgaggc acttactgat caagaagtta
    38461 tgggcttgat ccgcagaggg caggaattca agcaaggtgc taattggact ccgcaaaagc
    38521 gccagtactt tgctacaaac ctctttttcg aaaatagtac tcgcacacat aaaagcttcg
    38581 atgtagcgga gaaaaaacta gggctagaag tgattgaatt tgaagcaagc acaagctctg
    38641 tccaaaaagg ggaaacacta tacgatacag tactgacgat gtcagcatta ggcgtagacg
    38701 tagcggttat ccgtcatggt gatgagaact attatgacga actgatacaa agtaaaacaa
    38761 tccagtgttc gattatcaat ggaggagacg gaagcggaca gcatccaacc caatgcttgc
    38821 ttgatttgat gaccatttat gaagaatttg gtcattttga aggtctgaaa gttgccatcg
    38881 taggtgatat cactcactct cgcgtagcta aatccaatat gcagatgtta aaacgtctag
    38941 gcgcacaagt attcttctca ggtcctagag aatggtacga cgatgaattc gaagtgtacg
    39001 gacattatat gccattggat gaactactag atcaagttga tgtcatgatg atgcttcggg
    39061 tgcaacacga acgccatgat ggaaaagaaa gtttctcaaa agaaggctac catcaggaac
    39121 atgggttaac agttgagcgt gcgaagaagt tgcaaaaaca tgcaatcatt atgcacccag
    39181 caccagttaa ccgtgatgta gaattagctg attcattagt ggaaggatta cagtcgcgga
    39241 tcgttcagca aatgagcaat ggagtattcg tcagaatggc aatcttagaa gcagtgctaa
    39301 atggaaaagc gtaattatag gaggatgaaa aaatgaaaac actcattaaa aacggtcaga
    39361 tcaatacacg aaaaaatatg acgacaccag cagaaatttg gatagaagat gggcgaatca
    39421 aagcaatcgg tacaggattc tcagaagccg aatttgatga agtgtttgat gcaaagggac
    39481 aattgatcac acctggttta gtggacgtcc atgttcattt gagagagcca ggatttacat
    39541 acaaggagac gatcgaagct gggactcgct cagctgctcg tggcggtttc actactgtat
    39601 gcgcgatgcc gaatttaaat cctgtacctg atacggcaga aaagctgaga caagtatatg
    39661 acatcattag aaaagatgca gttgtgaagg tattgcagta tgcgccaatc acagaaaatc
    39721 tgcgaagtga gaaattagtt gatcaagaag cactgattga agaaggtgct tttgctttca
    39781 caaatgacgg tgtaggtgtc caaacagctg ggacgatgta tctggctatg aaagaagctg
    39841 caaaaaacaa taaagcccta gtagcccata cagaagatga atctttatta tttggcggcg
    39901 ttatgcacgc tggcaagaag gcagaagaac ttggtcttcc cgggatctta agcgtaaccg
    39961 agtcttctca aattgctaga gatctgttgc tagctgaagc aactggtgtt cattaccatg
    40021 tttgccatgt ttctactaaa gaaagtgtcc gtgtaatcag agacgcaaaa aaagcaggaa
    40081 tccacgtaac agcagaagtt tcaccccatc atcttatttt gatcgacgaa gatattcccg
    40141 aagatttcgg cttttggaaa atgaacccgc cgctaagagg acgggaggac agagaagctt
    40201 tgatcgaagg cttgcttgac ggtacgatcg attgcatcgc tacagaccat gccccccatg
    40261 gattagaaga aaaaagccaa agtttcatga aatcaccatt tggtatcgta ggaagcgaaa
    40321 cagcgtttca actgatctat actcattttg tagaaactgg tcgattcacg ttggaacaag
    40381 tgatcaattg gttggcagtt aaaccggctg agatttttgg tttgaatgca ggaacgctaa
    40441 cggttggtgc ccccgctgat gtagcagttt ttgatattac acaaacttgc acgatcgata
    40501 aagaagactt tttatcaaaa ggggagaata caccttttat cggctggaaa gtaaaaggcg
    40561 aaacacaaat gacttttgtc aacggaaaac ttgtgtggca gaagggagaa taaaagtatg
    40621 gaacgtttgc ttatattaga agatggaaca gttttcgaag gaaaggcttt tggtgcagat
    40681 gctagtgtct tcggagaaat cgtttttaca acaagtatga ctggttatca agaaactatc
    40741 actgatcaaa gttttaacgg tcaaatcatt acatttacct atcctatggt gggtaattat
    40801 ggggtaaata gagatgatta tgaatcgatt tctccaacat gcaaaggagt agtagtaaaa
    40861 gaacatgcac gtgtagcttc aaactggcga aaccaaatga cgctagattc atttttgaaa
    40921 caaaaaggaa ttcctggaat atcaggtatc gatacgcgcg cccttactcg caaaatccgt
    40981 gaagtcggaa cgatgaaagc tagtatagtt gatgctggag attccttcga acatgcattt
    41041 gatcagctga aagcaaccgt tctagcaacc aatcaagtgc agcaagtctc aactaacaaa
    41101 ccttatccaa gtccaggaac aggtcggaaa gtcattgtca ttgacttcgg cttgaaacat
    41161 agtattttac gagaattgag taaaagaaac tgtaacctca cagtacttcc ctataacaca
    41221 gatgccgaga cgattttagc gctatcacca gacggagtca tgctgacgaa tggacctggt
    41281 gatccaaaag atgtgccaga agcaatcgaa atgatcaaaa aaatccaagg aaaagtaccg
    41341 atttttggta tttgtctcgg tcaccagtta tttgctttag ccaacggtgc agatacctat
    41401 aaaatgaaat tcggacatcg aggattaaat cacccggtac gagaagtagc gaccggaaga
    41461 attgatttta cttctcaaaa tcatggctat gcagtcgatg aagccacgat tgatccagaa
    41521 aaactcatcg taactcatgt agaagtaaat gacggaacag tagaaggagt caaacacaga
    41581 gattatcccg ctttcagtgt gcagtttcat ccagatgctg cccctggtcc gcatgatgca
    41641 ctacatttat ttgatgaatt tatggaaatg atggacgcag gaaaggagca gtaaacagat
    41701 gccgaaacgt acagatatca agaaaattat ggtgattgga tctggtccga tcatcattgg
    41761 tcaagccgca gaatttgact acgcaggaac acaagcctgc cttgccttaa aagaagaagg
    41821 atatgaagtg gttttagtaa attctaatcc tgcgacgatc atgacggata aagaagtggc
    41881 agatcaagta tatatcgaac cgatcacact tgaatttgta tcaaggattc ttcgaaaaga
    41941 gcgtccagat gctctccttc caactttagg cggacagaca ggcctcaata tggcaatgga
    42001 gctggcagca tcaggtattt tagaagaatt gaacatagaa cttctaggaa caaagctttc
    42061 tgcgatcgat caagcagaag atcgtgatct attcaaacag ttgatgaaag aattgaatca
    42121 gccaatcccc gagtctgaaa tcgtcaatac agtagaagaa gctgtagatt ttgcaaataa
    42181 aatcggctat cctgtcatcg ttcgtccagc ctttacttta ggcggaactg gtggaggtat
    42241 gtgtgaaaat gaagaagaat tacgtatcgt atcagaaaat ggattaagtc tttcccccgc
    42301 tacccaatgt ttgattgaac gaagtattgc aggttttaaa gaaattgaat atgaagtgat
    42361 gagagattcg gctgataatg caatcgttgt ctgcaatatg gaaaattttg acccggtggg
    42421 tatccataca ggtgattcta tcgtatttgc ccctagtcaa acattgtctg accatgaata
    42481 tcaaatgctt cgtgatgctt ctctttcgat tattcgagca cttaagatcg agggaggctg
    42541 taatgtccaa ctcgctcttg atccacatag ttttaattat tatgtgattg aagtcaatcc
    42601 gcgtgtttct cgttcatctg cgttagcaag taaggcgact ggctatccga tcgctaagct
    42661 agctgctaaa atagcgcttg gattaacatt agacgaaatg aaaaatcctg ttacaggaac
    42721 gacttttgca gaatttgaac ctgcattaga ttatgttgta gctaaaattc ctcgctggcc
    42781 gtttgataag tttgaaaacg gagaacggct tttaggcacg cagatgaaag caactggtga
    42841 agtgatggct atcggtcgga atatcgaaga gtctttattg aaagctgtgc gttctttaga
    42901 aatcggtaca caccatatcg aacttcctga gttggcagac atcacggacg atgacctaat
    42961 ccaaaaagtg gttcgagcac aagatgatcg cctgttttat gtagctgaag ctattagaag
    43021 agggtacacc atagaagaat tagcggattt gacaaaaatc gatttattct ttttagataa
    43081 actgttgcat atcgtagaaa tcgaacagca gttgaaacag cagccgttgg atgacaagat
    43141 attgaaaaca gcgaaacaaa acggttttac agacaaaaaa gtggcggagc tgtgggaaat
    43201 aaacgaagaa gccgttcgcc agatgagaaa agaaaatgat ttgattcctg tatataagat
    43261 ggttgacact tgtgcagcgg aattcgaatc aaaaacacct tatttttata gttcctatga
    43321 atatgaaaat gaaagttcac gatcagaaaa gccctcaatt ctagtactgg gatctggtcc
    43381 tatccgtatc ggacaagggg ttgaatttga ctatgcgact gtgcattctg tcaaagcaat
    43441 ccagcaggca ggatacgaag caatcatcat gaacagcaat cctgaaacag tttcgactga
    43501 cttttctatt tcggataaat tatattttga gccattgacc ttcgaagatg tgatgaatgt
    43561 gatcgagcta gaacagccga taggagtaat cgttcaattt ggtggtcaga cagcaatcaa
    43621 cttagccgaa cctttgactg ctgctggtgt aaaaatctta gggacaacga tcgaagactt
    43681 ggatcgtgcg gaaaatcgtg atttattcga gcaagcgctg aaagagttgg atattcctca
    43741 acctttaggg gatactgcta caagtaaaga agaagccgtg gttatcgctt cgagaattgg
    43801 ttatccagtt cttgttcgtc caagctatgt attaggcgga cgtgcgatgg aaatcgttga
    43861 aaaccagcga gatttagaag attacatgga acatgctgtg aaagcatctc cagaacatcc
    43921 agtactagtg gaccgttact tgcttggtgg tgaatgcgaa gtggatgcga tttgtgacgg
    43981 tgaaacagta ctcatcccag ggatcatgga gcatattgag cgtgctggtg tccattcagg
    44041 ggattcaatg gctgtgtatc cacctcaaac attatctgaa tcgatcaaga aaacgatcga
    44101 agattacacg atccgcttag cattaggttt gaattgtgtc gggatgatga atatccagtt
    44161 tgtcatccat gaaaatgagg tttatgtgat cgaagtcaat cctcgagcaa gtcggactgt
    44221 tccattctta agtaaggtga caggaattcc aatggcacaa attgcgacga aagctatttt
    44281 gggagagaaa ctaaagacac ttggttatga aaacggactt tatccagaaa caaaagaagt
    44341 tcatgttaaa gcacctgtct tttcttttac gaaattgcag aaagttgata cttacttagg
    44401 gcctgaaatg aaatcgactg gagaagtaat gggatctgac agacaattag acaaagcttt
    44461 gtacaaggca ttcgaagctt ctggattaca cttgcctgaa tatggagccg tattatttac
    44521 gattgcggac gaaacaaaag aagaagcact agaattagct aaacgtttta cagaaattgg
    44581 ctatagtctg ataggaacga aacatacagc tgcttatttc gaaaaaaatg gtctggtcgt
    44641 tgaaacagta gcgaaaattt ctgaggaagc agcagaaaaa aatgtagtcg acttaataag
    44701 agatggtaaa acacaagtgg ttgtcaatac gattgataaa gatcggggaa atgcttctaa
    44761 agacggtttc atcatccgaa gagaagcagt tgaacatggt attccattgt ttacttcttt
    44821 agacacagca gatgcgatcg ttcgagtgat ggaatcccgt gctttttcaa ctaaccctat
    44881 ttaacggcga gcacatgtta agacaaaaag acgaaaaacc gttgcaggag gggacagatg
    44941 aaacaagaaa tgatggaaat cgttcagcaa aaacagctgg caccaaagat ttttgaaatg
    45001 acattgaaag gtgatctagt aaaagaaatg cagcaaccag gacagttctt gcatattctc
    45061 gtgccgcgtg cagacttgct attacgccga ccgattagct tgaatcatat cgaccacgaa
    45121 acaaatactt gccgtatcat ttatcgggtg gaaggtgagg ggactagagt cttctctact
    45181 ctttctgccg gagaccattt agatgtcatg ggtcctttag gcaatggttt tgatttgtcc
    45241 aatcttcata caggagacga agtatttata atcggtggag gaatcggtgt ccctcctcta
    45301 tatgagttat caaaacagtt agtcgaaaaa ggaattaagc caacgcattt tttaggtttt
    45361 gccacacatg aagtcgttta ttatgaaaaa gaatttaatc gtctaggaga aacaagaatc
    45421 gctactgacg atggaacata cggtatgcac ggaaatgtcg gtaatttatt gttaggaacg
    45481 aagacggaac ctacagctgt ttttgcatgt ggttcaaacg ggttattgaa gacagtggaa
    45541 cagctgtttt cttcgcatca aaatgtccag ttatcattag aatcccgcat ggcatgtggg
    45601 ataggggctt gctatgcttg cgtttgtcat acgccggaag atgaaacagg aacaaaaagt
    45661 gtgaaagttt gtgacgaagg accgattttt aaaataggag aggtaattat atgaatgaga
    45721 atcctttagc ggtcaaactt cctggcctag aattaaaaaa tcctatcatg ccggcaagcg
    45781 gctgtttcgg ttttggcaaa gaatacggaa aatactatga tttgaatcag cttggatcga
    45841 tcatggtcaa ggcaacgact ccaaatgccc gctttggcaa tcccacgcca agagtggcgg
    45901 aaacaccatc tggcatgttg aatgcaattg gtttgcaaaa tcctggtcta gacgttgtta
    45961 tgcataaact tcttccagaa ttagaggagt acaatgagtt acccatcatc gcaaatgttg
    46021 ctggtgcttg tgaagaagac tatgtagaag tttgtagcaa aattggcgaa gcaccaaatg
    46081 tgaaagcaat cgagctgaac atttcttgcc caaatgtcaa acatggcgga attgcttttg
    46141 gaacagattc tgatgttgct tttcaattaa cacaagcagt aaagaaagtt tcttctgttc
    46201 ctgtctatgt caaattgtcc ccaaatgtaa cagacatcgt tccaatcgct caggcaatcg
    46261 aagctggagg ggcagatggg tttacgatga tcaatactct tcttggtatg cggattgacc
    46321 ttaagacaag aaaaccgatt ttagccaatc aaacaggtgg actctccgga ccagcaatca
    46381 agcctgtcgc tattcgtttg attcaccaag tagcaagtat atccagcctt ccaatcattg
    46441 ggatgggcgg cgtgcagaca gtggatgatg ttcttgagat gtttatggct ggagcaagtg
    46501 ctgtagctat agggaccgcg aatttcaccg atccgtatat ctgtcctaaa ctaattaaag
    46561 agctccctgt gcgaatgagc gaactaggca tcgaatcgct ggaaagatta atcaaagaag
    46621 tgagagagga acgtgaacga tgaatcaact agaccaacga ccaattattg cattagattt
    46681 ttcaactagg caagaggtag aagactttct tcgatttttc ccgaaagaag aaaaattgtt
    46741 tgtgaaaatc ggaatggaat tgttctacca agaaggacct gaaatcgtac gttatctaaa
    46801 agaggctggt cataatgtat ttttagatct gaaacttcac gatattccga atacggtcga
    46861 aaaagcaatg cggggattgg caaagcttgg tgttgatctc acctgtgttc atgccgctgg
    46921 cggtattcgt atgatggagg cggcaatgcg aggattagaa gaggggactc cagaaggtgg
    46981 aaaacgtccg ctacttctag ctatcactca gcttacttct acaagtgaag aagaaatgca
    47041 tgccgatcaa ctaatcgaag tttctttaga aaaaagtgtg atccattatg ctagctgtgc
    47101 caaaaaagca ggattagatg gtgtggtttc ttctgcttgg gaagtagaag cgatcaaaga
    47161 aatggcagga gacgaatttg tttgcttaac tccgggtata agaccagaag gaacagtcgc
    47221 aggagatcag acaagagtag tcacaccttc tcaggcaaaa aagatcggct caacttttat
    47281 cgttataggt cgaccaatca ctcagtcaac taatccttat aaagcatatc aaacgattca
    47341 aacagaatgg agctaaccta aaatgaatgt tgaacaaagt atcgcaaaag acttattaga
    47401 aattgaagca gtatttttaa atccaagtaa tccttttaca tgggcaagtg gaatcaaaag
    47461 cccaatttac tgtgataacc gaatcacgat gagctatcca aaagtccgaa aagagatcgc
    47521 aaaaggatta gcaagcaaaa tcaaagaagc ttaccctgaa gtacaagtga ttgctggaac
    47581 tgcaacagca ggaatccctc atgccgcatg ggtagcggaa atactggatt tgccaatggt
    47641 ctatattcga agtaaggcga aagatcatgg gaaaggtaac caaatcgaag gacgtatatt
    47701 tgaaggtcag aagatggttg tgatcgagga tttgatttct acaggcggaa gtgtcttgga
    47761 agcagctgaa gcagcaaaaa gagaaggtgc ggatatcctt ggtgttgcgg ctatctttac
    47821 gtatgagttg ccaaaaggaa aagcaaattt cgaaaaagcc gaaatccctc ttatgacgtt
    47881 gaccaattat tctgtattga ttgaagcagc tttagaagat cgttatatcg atgagcaaga
    47941 attaactctg ctaaaagaat ggaaaaaaga tcctgaaaat tggcagattt aagcgcgctt
    48001 gatgaagata gagaaatccg atttgtgtct ccagaatcat caattggaat agcaaaaatc
    48061 caaaaactga ttgcgagaag catcttttca tcaggtatga aaagaaactt ctatcgtgat
    48121 cagtttttga tttttttaaa attcattttt ctaagactgg ttagcagaaa gaagagaata
    48181 atctcttctc ttttttctat tatatataga ttttctctat tttttggtaa gggagctgtt
    48241 tcaaaaatgg taaagagcgg aaatgttgcg aatatcagtt atttaatgat atgatattcg
    48301 gaaaaagaaa tctcaaaggg aggtaacttt tatggggttg aatgaattta ttttaggatt
    48361 gaacaattta gagacgatca caagggcacc tggatttttt aaatatacag agcatacagt
    48421 tgcagcacat tcgtatcgtg tagcatctat tgcgcaagtt ctaggagaca ttgaagaagc
    48481 gaatggacaa ccgatcgatt ggaaactgct ctatgaaaaa tcattgaatc atgactacac
    48541 agagcgtttt attggtgata tcaaaacgcc ggtgaaatac gcaagcaaag agttaagagg
    48601 gatgctgcaa acagttgaag aaaagatgac ggacgaattc atcaaccaag agattccagc
    48661 tgagttccaa gaagtttatc gccgtcggtt gttcgaagga aaagatgaaa ccgtagaagg
    48721 agaactatta gccatttcag ataaggttga ccttctttat gaatcttttg atgaaatcat
    48781 caaaaataac ccggaaaaag tttataagga gatgttcatt gaggcagtga ctacgattaa
    48841 aagctttgaa catcggcctt ctgttcagta tttctttaaa gagatatttc cggaactatt
    48901 gaaccaggaa ttttatggaa aagaggcgtt tttagaaacc gtctcaacga ttgtaaagaa
    48961 agaagaaaaa taaaaatgat atgagatgca gggggaagta tagttgaaaa agaatatgga
    49021 tgtcgaatgg ggctattctg gagacaaagg tccggaaaat tgggcgagtt tatgtgattg
    49081 gtttgcgaga ggtgcggaat ttccattgca gtcgcctatt catttgacca agggggaaga
    49141 aaccaaaata gaaggagaca cgctttcctt tcattatcaa aagcaacggt ttactgacaa
    49201 ggaattcaaa aacacgattc atttagtacc ttttgaccaa ctcagttatg tagagttcaa
    49261 gaaagaacgc tattatttga cagatattca tttccacttg ccttctgaac atatcatcaa
    49321 cggaaaacag gaagatattg aatttcattt tgttcatatg aacagcaaaa aagagaatct
    49381 agttgtgggt gtcatgtacc agctaatggt acaggaaggt tggctgtata atcaagaaaa
    49441 tggggaaagt tggaacttag aaaaacatga gcattgggta aatccggatg tgttctttcc
    49501 ggagcaaaaa agccatttcc attatattgg ctcattgaca actccgccta ccagcgggcc
    49561 aatccaatgg tttgtaatgg atcatgtagg aaaactgaac caagagtttc ttctcccctt
    49621 cgatggtcag tatgctcgac cgaacaaccg accaatccag cccttgaatg gaagagaaat
    49681 ttattatttc gaggagtttg agcaatgaat attcagcaga tgaaatacgt ggtcgctgta
    49741 gcaaacaatg gtagtttcag agaagcggca aagaaaatgt ttgtctccca gccaagtctt
    49801 tcagctggta tcaaagaatt agaaaccgag ttagggatca cgctgtttac tcgaacgaat
    49861 cgaggggcat atttaacaga agaagggcaa gacttcttaa atcgtgccga gaaaatattg
    49921 gtccagcttg atacattaga aactcactat ctaacgagtg aaaagagaga caatttttcg
    49981 atcgctgccc agcattatga tttcttaggt cctttgaccg cacagctact cgaggaattc
    50041 aaagacgaga tcaaacaatt tcggatcatg gagacgacaa cagcgagagt gatcgaagaa
    50101 gtcaaagagc agcacagtga gatcggcatt atttatatga atgagcataa tcaagctggt
    50161 atcagaagat atttacaaca aggagagcta agtggccgca gcattggaaa attcaaaacg
    50221 catatttttt taaggcaagg acatccatta gctgaacacg cagagatcac caaagaagaa
    50281 ttgttatctt atcctcaagt tcgttttaca caggatggaa ataatttccc gtatttttat
    50341 gaagacctta tcgagatccc tgatcaagaa acagtgattt atacgagtga tcgaggtact
    50401 ttgatgaata tcgttcttga aactgatgct tacgcttcag gatctggtat tgtgattgga
    50461 gggattcgcg agcacttgcg gttaatccct ttggcagaag gcgaactaaa tgaattttat
    50521 atcatttatt cggcgaaacg tccgctcagt gaaatcgctc aaagatttat caaagagctt
    50581 actcggttac tggaccagca gagctaagaa aagcagatga gaacgctgtt tattgaacac
    50641 cgttgatcaa aaaagagggg ttgtgacaga attttgtcac aactcctctt tttgtagcaa
    50701 acaatttata actaattgct gttgtgggaa agtacgcaaa tatgattcta gaaacactca
    50761 ttgattacct gttttgtttc atagctgtaa ttttttcttc ttctggtgtc acgataatcg
    50821 tcttttggtt ttcataaata acataaccag gcttggcgcc atttggtttt cggatatgct
    50881 ttacctgtac aagatcaacc ggcacttggg cagagtatcg gtattttgaa aaataggcag
    50941 ctaactcggc agcttctgta attgtttcat ctgagggctt gtcactttta atgatgacgt
    51001 gcgaaccggg tatatttttt gcatgaagcc aatagtcggt ttttttagct gtcttcattg
    51061 tcagctggtc attttgaaga ttgtttttac caacaagaat gagcgttccg tcagaagaaa
    51121 agtattgatc aggctgagat ggtttcttac gtttttgttt ttttaagttc ttctttttca
    51181 ggtatccttc tgaagtcaat tcttctttaa ttgcttcgat atccattggg ccggcaattt
    51241 ccagttgaga taagacagat tcaagatatt ggatttcatc tttggcttct tggatttgtt
    51301 cgccaatcag cttaacagcg ttcttcagct tttggtatcg atggaaatat ttctgtgcat
    51361 tttgatttgg tgtcaatgcc ggatctagtg ctattttgat tggccgatct tcttcataat
    51421 aattaggtaa aacaacttct tttgcgccgc gtggtacttg tgtcagaaaa gtagtaagta
    51481 gttcgccatt tctacggtaa ttctcagcgt tttcggattc tttgagtgtt tgttcacgtt
    51541 ttttcaattt atttttattt cgttttagtt cattttcgat ttttcgaatc agttctccgc
    51601 cttgttgttt tgcccgatct ttctctgctt tttcgtgata atagctatct aataattgac
    51661 tgagtgttgg ataagctgtt acagcagatg cctgttcgga caatacctga taagcaatcg
    51721 gtgtgaaaaa atctttattt tccgtttcgt aaaaagtagg aataggctga tggctgatgg
    51781 ctgagaaaaa ttcgtcccat acaaccatct tttcattagg acgttccagt aatcttttgg
    51841 tcagctcttg agcgatatcg aaaccgattc cctgaaactg acgttggatt gcttttggat
    51901 ctagttcagt ttgggaaagc cgctgaaaga ttttttcttt ctcggagcta aatgggttca
    51961 agacctcttg ttttggcgga gcaacatatt ctacaccagg aagcaaagaa cgataagtgt
    52021 tttgagagct tccaatgtgt ttgatcgcat ccagtatttt tccagtttct cgattaacta
    52081 agacgatcgt actatgacgt cccattaatt caacgatcaa tatgatattt tgtagatcac
    52141 ccaactcgtt tcgtttagca aagtggaaat ggatcactcg atcattttcg atttgttcga
    52201 tgtcttctaa aatagcgcca tccaaatatt ttcgaagcat catcacgaag ttaggcggat
    52261 tatcaggatt ctgataatcg atttgggtaa tctgtacacg agcataactt gggtgcgcag
    52321 ataataataa tcgatggttt ttgccgcgtg aacgaatcac cagcacgatt tcattttcat
    52381 aaggctgatg gattttcgag atccggccag atagtaacgt ttcacgcaat tcgttgacca
    52441 tcgcgtgggt aaatacacca tcaaaggaca tggttcattc ctcatttctt ttcataagta
    52501 tattcattat aacgaaaaaa agaagaaaaa ccaatttggc cgaatagtaa agcaaaagtc
    52561 tagaaaaatc ttggactaat tacataaaaa acagtgtttc tatcgttgaa atccaaattt
    52621 ttaggt
//
LOCUS       DAFEEZ010000011        52112 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000011
VERSION     DAFEEZ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.011"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            301..1146
                     /locus_tag="LP245_000768"
     CDS             301..1146
                     /locus_tag="LP245_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1518705.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1427..2647
                     /locus_tag="LP245_000769"
     CDS             1427..2647
                     /locus_tag="LP245_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBL1518706.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2644..5364
                     /locus_tag="LP245_000770"
     CDS             2644..5364
                     /locus_tag="LP245_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1518707.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5348..6292
                     /locus_tag="LP245_000771"
     CDS             5348..6292
                     /locus_tag="LP245_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1518708.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6361..7371)
                     /locus_tag="LP245_000772"
     CDS             complement(6361..7371)
                     /locus_tag="LP245_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1518709.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7551..7895)
                     /locus_tag="LP245_000773"
     CDS             complement(7551..7895)
                     /locus_tag="LP245_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBL1518710.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7888..8322)
                     /locus_tag="LP245_000774"
     CDS             complement(7888..8322)
                     /locus_tag="LP245_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBL1518711.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8460..9197
                     /locus_tag="LP245_000775"
     CDS             8460..9197
                     /locus_tag="LP245_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518712.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9190..10401
                     /locus_tag="LP245_000776"
     CDS             9190..10401
                     /locus_tag="LP245_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518713.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10605..11387
                     /locus_tag="LP245_000777"
     CDS             10605..11387
                     /locus_tag="LP245_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBL1518714.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11457..12119
                     /gene="trmB"
                     /locus_tag="LP245_000778"
     CDS             11457..12119
                     /gene="trmB"
                     /locus_tag="LP245_000778"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBL1518715.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12217..13971)
                     /gene="ade"
                     /locus_tag="LP245_000779"
     CDS             complement(12217..13971)
                     /gene="ade"
                     /locus_tag="LP245_000779"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBL1518716.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14103..15032
                     /gene="tadA"
                     /locus_tag="LP245_000780"
     CDS             14103..15032
                     /gene="tadA"
                     /locus_tag="LP245_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBL1518717.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14989..16038
                     /locus_tag="LP245_000781"
     CDS             14989..16038
                     /locus_tag="LP245_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBL1518718.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16035..16313
                     /locus_tag="LP245_000782"
     CDS             16035..16313
                     /locus_tag="LP245_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBL1518719.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16288..16758
                     /locus_tag="LP245_000783"
     CDS             16288..16758
                     /locus_tag="LP245_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBL1518720.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16775..17077
                     /locus_tag="LP245_000784"
     CDS             16775..17077
                     /locus_tag="LP245_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518721.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17094..17465
                     /locus_tag="LP245_000785"
     CDS             17094..17465
                     /locus_tag="LP245_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBL1518722.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17437..17796
                     /locus_tag="LP245_000786"
     CDS             17437..17796
                     /locus_tag="LP245_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518723.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17968..18975
                     /locus_tag="LP245_000787"
     CDS             17968..18975
                     /locus_tag="LP245_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1518724.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19000..20184
                     /locus_tag="LP245_000788"
     CDS             19000..20184
                     /locus_tag="LP245_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBL1518725.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20621..22204)
                     /locus_tag="LP245_000789"
     CDS             complement(20621..22204)
                     /locus_tag="LP245_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL1518726.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22782..22925)
                     /locus_tag="LP245_000790"
     CDS             complement(22782..22925)
                     /locus_tag="LP245_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBL1518727.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23148..23627)
                     /locus_tag="LP245_000791"
     CDS             complement(23148..23627)
                     /locus_tag="LP245_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL1518728.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23700..23984)
                     /locus_tag="LP245_000792"
     CDS             complement(23700..23984)
                     /locus_tag="LP245_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518729.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24062..24256)
                     /gene="ssrS"
                     /locus_tag="LP245_000793"
     ncRNA           complement(24062..24256)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="LP245_000793"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24328..25614)
                     /locus_tag="LP245_000794"
     CDS             complement(24328..25614)
                     /locus_tag="LP245_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBL1518730.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25752..26423
                     /locus_tag="LP245_000795"
     CDS             25752..26423
                     /locus_tag="LP245_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBL1518731.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26389..26877
                     /locus_tag="LP245_000796"
     CDS             26389..26877
                     /locus_tag="LP245_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBL1518732.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26890..27837
                     /gene="prmA"
                     /locus_tag="LP245_000797"
     CDS             26890..27837
                     /gene="prmA"
                     /locus_tag="LP245_000797"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBL1518733.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27838..28602
                     /locus_tag="LP245_000798"
     CDS             27838..28602
                     /locus_tag="LP245_000798"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBL1518734.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28835..31048
                     /locus_tag="LP245_000799"
     CDS             28835..31048
                     /locus_tag="LP245_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBL1518735.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31059..31505
                     /locus_tag="LP245_000800"
     CDS             31059..31505
                     /locus_tag="LP245_000800"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBL1518736.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31676..32935
                     /locus_tag="LP245_000801"
     CDS             31676..32935
                     /locus_tag="LP245_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBL1518737.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33024..33971)
                     /locus_tag="LP245_000802"
     CDS             complement(33024..33971)
                     /locus_tag="LP245_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL1518738.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34365..35657
                     /locus_tag="LP245_000803"
     CDS             34365..35657
                     /locus_tag="LP245_000803"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBL1518739.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35672..37441
                     /gene="aspS"
                     /locus_tag="LP245_000804"
     CDS             35672..37441
                     /gene="aspS"
                     /locus_tag="LP245_000804"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBL1518740.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37550..38425
                     /locus_tag="LP245_000805"
     CDS             37550..38425
                     /locus_tag="LP245_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1518741.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38691..40574
                     /locus_tag="LP245_000806"
     CDS             38691..40574
                     /locus_tag="LP245_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBL1518742.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40649..40933)
                     /locus_tag="LP245_000807"
     CDS             complement(40649..40933)
                     /locus_tag="LP245_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBL1518743.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40923..41657)
                     /locus_tag="LP245_000808"
     CDS             complement(40923..41657)
                     /locus_tag="LP245_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBL1518744.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41786..42409
                     /locus_tag="LP245_000809"
     CDS             41786..42409
                     /locus_tag="LP245_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBL1518745.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42601..43722
                     /locus_tag="LP245_000810"
     CDS             42601..43722
                     /locus_tag="LP245_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBL1518746.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43729..46857
                     /locus_tag="LP245_000811"
     CDS             43729..46857
                     /locus_tag="LP245_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBL1518747.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46876..50070
                     /locus_tag="LP245_000812"
     CDS             46876..50070
                     /locus_tag="LP245_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBL1518748.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50216..50923)
                     /locus_tag="LP245_000813"
     CDS             complement(50216..50923)
                     /locus_tag="LP245_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL1518749.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51688..52086
                     /gene="spxA"
                     /locus_tag="LP245_000814"
     CDS             51688..52086
                     /gene="spxA"
                     /locus_tag="LP245_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBL1518750.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT        17096 a         9067 c        10783 g        15166 t
ORIGIN      
        1 atcttttttt gtttaaatct tttgctaagt tgaactaata gagtctttta tgaatatcga
       61 agttagtttt tcacctaact tcgtttttta tagttggtta ttataaaata gtaatatagc
      121 tgatttggat tcaattcata tttatttata aatcaaaaat acagagaata gtatataaat
      181 gtcctttcct attcttaaaa tgatgtttgt acttacttaa attaggtata attagtatat
      241 gttttgtgag aaatttagac ttacaataag cagtgaattt ataatcaacg tataggagac
      301 atggatgaaa tgaaactaat tggtatagat ttagacggta ctcttttgaa ttctgaccag
      361 agcattagtc aaaaaaatgc aagaacaatg aaacatttac cggaagactg ttttccattc
      421 atttgttctg gaagagaagt agaagacatt aataatattc tcaaaaaatc tggtttaagg
      481 ataccagcag tagggttaaa tggttctgtt ggatttgatg gagaaaaaaa gatatttgag
      541 tcttccttcg ataaaaatga tgtaaaaaaa attgattctg tcctatcgaa atttccaacc
      601 aaaatatata caaatctcgg aagttatgaa tctcagaatt ataaaaataa aatgaaaaaa
      661 atttttcacg aggtagggag tgaattttct atcaaagagc taaactatga gcttgagtat
      721 gaaaaatcta tttgttcaat cccttataat aatattgagg aaattataga aaaggatgct
      781 atcagcattt acaaattttt tatttttatt cctaatcgtc aattgaaagc taatatattt
      841 aaccatttga aaaagatgct aaatgtgtct gttactgaat cggcacctgt aaatattgaa
      901 atcgtacctc aaaatgtatc taaaggtgtg gtgtttgatc gtttggaatc aatctacaat
      961 ttaaagaaac ctttgagaat cgcgatcgga gatagtttaa atgacttatc tatgtttgaa
     1021 agtgcagata ttagttttgc aatgggaaat agtcatcaag aaatcatgaa aaaagctgat
     1081 tatgtcactg tttcaaatga taaagacgga gtatctcaag catttgaaag aattcttacc
     1141 atataaacta attaaggtag tatagaacat agaattctaa atacggaaaa atggagcata
     1201 aattccagta caaatagtac ttcttcagtg tcaaacgaag cgaatataac atagatattt
     1261 aggattgtga caaaaatcat gtcacaatct ttttttcgaa taaacttatt ttttgaagtc
     1321 ggccatttat cgtaatttct ttgcataata cgaacaaatt ttcggttatt gatgaaaaaa
     1381 aacattgaaa atggtatgat aaaagaaaaa aaggaggaaa tttttaatgg tgaaatttat
     1441 ccatgcggca gatttacata tggatcggtc atttgaagga ctgacaactc ttgataaaac
     1501 tgtacaggaa aaactattga agacgaatct gaccgtttta tcaaatatca ttgaacaggc
     1561 aataataaat aacgttgatt ttgttttact tgcaggagat aattttcatc aaaatcgtcc
     1621 ttcattaaaa atacagaaac atttttcaga acagatgaaa cggttagaaa agaaccatat
     1681 acctgtattt ataatattcg gaaatcatga tttctatcaa aaagagcggt attggttctc
     1741 ctttcctaaa aatgtccatt tatttacatc cgaaacggta gagacaaaaa aaataacgat
     1801 aaaaagtgga gaaactgtct ctctcagtgg atttagttat cgtcaaccgt ggattcaaaa
     1861 agacaaagtg atggaatttc cttctagaga actcacagat taccatattg ggttgtacca
     1921 cggggaacct ggcgtctctc aaaaaggaaa ctatgctcct ttccaaccct caaagatgca
     1981 agaaaaggga tacgattatt gggctttagg gcatatccat gtgccaacgg tcttaaatga
     2041 aaagcaaaca attgtttatc caggtgcgcc tcaaggtcat actaaaaagg aacaagcttc
     2101 tacatctatt ctactagttg aattaagtaa aggaagttgc caaatacatc cgattaaagt
     2161 agcagaggtc tattggaaga caaaggaaat atcattgagg aaagcaagaa cgacaaaaga
     2221 ggtcattgtt cacattcgtc agcagctttc aaaagtagag gatggattta gtttaattga
     2281 gataaaatta aaagattatg accatctcaa tacagatgtt ttggaacgga tacaatcagg
     2341 agagctatta gactatttgt tagaggaatt ctcagatagg ataaatgatt tctttatttg
     2401 gcgtatttct ctcatagaga atacttttta tacgaagacc ccacttgctg cttctgctaa
     2461 attgatggaa cagttatttc aatactatca gacacctcaa gatttccaac aaattttaaa
     2521 tgaagtatat agtcatcaag aagcggctag aatattgagc gaactgccgg aatatcaaga
     2581 agaaacactt gaaaaagcca agcagctgct taatcaagat tttttatttg aggaggatca
     2641 ggaatgaaga ttttaaggat cgagattgct gcttttggaa aatggcgtca aaaaagtttt
     2701 gacttttatt caggcaatca gctgatctat gggggaaacg aagcaggaaa atcaacgatt
     2761 tatcaattta ttcaagcaat attatttggt ttcccttcaa aaggccgtaa aaaaaaggat
     2821 tatacaccaa aagacggctc agcctatggc ggcaaaatat ggcttaaaca tcctgtatat
     2881 ggtgaatttg ctgtcgagcg ctacaagcag caaaatcgcg gaaaatcgaa ggtgtggctg
     2941 ggggatcaag tgggaagtga tgagttacta gaaaaactga tcgcaccttt gacgaaagag
     3001 ttattccagc aggtatttac tttccagcaa gagcagttga tggaactaga tcatttgaga
     3061 gaaaaagagc tacatgatgc gctgatttct ttaggcatca cgggcagttc tcaagtattc
     3121 caaaagcggc aagaatatta tcagaaagca caacaattat tcaagaaaaa aggccaaaaa
     3181 ttactaatca atcaaaaatt aaatgaatgg aaagagctgc aagaaaaaat tcatcaaaaa
     3241 caagaacagg aagcttattt tggcaagttg atccaacaag aacaggaata cgagtcgcaa
     3301 cagcagcagt tattggcaca attaaaagag gcgaacaaac aattttcatt agccagacag
     3361 caagaactta atttttcttt atatgaagaa tggcaatctc tcaaaaaaaa cagcactaca
     3421 ggtcttcctg atgagcaact tcttttagat ctggagtctt tctccaaacg gtatcagcaa
     3481 acaaatgagc gtttggaaga attagaagca acactggaaa agcatagcgg gatggatcag
     3541 cagtcagcca gatattattt ttatttagag caggagcagg aactaaaaga tctccagcaa
     3601 cttcaattta cagcggaaca attaaacgaa gaatggcaaa gattacaaat tgagactaga
     3661 gaaacaaatt cagaattgaa gattttggaa caaaggtggc attggcagaa aaatccgtta
     3721 ccggaagaat ttttatatga agaagaatgg aagcatcttc tggctgaaga aagaaggatt
     3781 gctgatctag aaagccagat ttctgtgcgt ctccaaatag ctaaagaaca gcaagagatg
     3841 attgaagcag aagtgaatga cttggaagag acctatccag cattattaca aaatcagtca
     3901 gagatagcac cagtctcttc atctaaaccg tatatgctga tggctggcgg agcaataatc
     3961 attgcaggta tatttgtacc aatgcccttg aaagtgatcc ttttactaat tggtgcaggc
     4021 atgattggct atttcttcta caaaaggcaa ccaaaaatta aaactaaaaa tgatttctct
     4081 gagataaaag gaatgtggca agaaaaacta ggacaacttg atctagcctt agctcaatta
     4141 gctgaagcag aagaaaaaca aaagagaact ggagaagaaa aacagattct tcagcaagaa
     4201 gtatatcgtt ttgcggatca tcggcactta ggaaagatgg atacgctcaa actcatgaaa
     4261 gaatatggac aggaagtcat agattatcag aaattatatg gcgtatttga gcggaaacat
     4321 aaaagagaac aggaaataca agaaaaacta cgacaaatcg accaaaaatt tgagtttgtt
     4381 aaagaatggt taccgataca agataagaca atttcagaaa aaatggtatt gctttcccgt
     4441 tttatacaag agatggaaca gatgaaattt gccagaagct atcagcaaaa tactttattg
     4501 aagcaagaaa tcaatcaatt gaaaaagaaa caaaaagtat ggatacaaga atacagcgaa
     4561 caattgactc aagcaggctt atcttatcct tcggaagtac ctgtcttttt acaaaaagcc
     4621 aaacaagccg aacagcagat gaaaagatac aatgaattat cggaaatgct tactccacta
     4681 tttcctgaag agctgacaaa agagaaatta tctgtaagac tgcgccaact gaaagaaaag
     4741 caatcccaac tccagcaaga agaaaaagaa gcaagtgaaa atcggcaacg actccaactt
     4801 caagtagaag agttgcaaag agacggcaca ttggacgaac tttatcaaca agctagccgg
     4861 caaaaagcaa aattacagga attactggag gaatggggag cacttgaaat cgccgggaca
     4921 ttcttaggtg atctttcaac agagatgagt gaaagacaat taccccagtt gttaagagca
     4981 gcaggtgatt atttaggtat tttaacaaaa ggaaattatc agaagatatt actgaaaaat
     5041 gatacactga ctttaacaga cggatataca gaatttccca tctatgagtt atctacaggt
     5101 acgaaagatc agctgattat ggcgatgaga tttgcttacc tctcattaga agctaaccgt
     5161 tcgatatgcc cgatcatcat tgatgatggc tggcttcatt atgatcatca gcgaaagtat
     5221 caattagctg aacttttagc taaatttgga gaaaagtatc aaataatttg tttttcttct
     5281 gataaagaaa tggtaagcta ttaccatgag atgaaccaaa tcgtaaaaca attagaagga
     5341 gcaaataatg aaaaaaattc gtgatttagt aatcgatgag cagtttgaac aatttgtcct
     5401 gatcaaaagt gcagatgtaa gaatcgctaa aaacggaaaa aaatttattg cttttacttt
     5461 ccaagatact tcaggtacta tcgatggtaa atactgggat gcttcggagg aggaaatcaa
     5521 taaatttaca gccggcacag tcgtttttct aaacggtaaa agagaggttt atcaaggaaa
     5581 ccctcaagta aagattcttc atatgcgctt aacaagggta gatgagccag gagagcctag
     5641 tttatacatg gaaagagccc ctttgaagaa agaagaaatg gaagaagaaa tcaatcaatt
     5701 gttgtttgag atcaccaatg cgcattggaa tcgtattgtt cgctatctac ttaataaata
     5761 tcaaaaacaa ttttttgagt ttccggcagc aaaaagaaac catcatgcat ttgccagtgg
     5821 attagcttat catactttga caatgcttca cttagggaaa tcaatcgccg atgaatatcc
     5881 tgagctgaat cgagcattgt tgtatgctgg tatcattttg catgatttag gaaaggtgat
     5941 tgaactttcc ggtcctatgt cgacagaata tacgcttgca ggaaatttga tcggtcatct
     6001 ggtattgatt gacgaagaaa taactaaagc ctgtcttgcg ttgaaaatca gcgaagctga
     6061 cgaagatgtt ctcgtattac gtcatatggt tttagcacac catggcttat tagaatatgg
     6121 ctcacctgta cgtccaagaa taatggaagc agaaatatta catcaaatcg acaatatcga
     6181 tgcttcgatg cagatgatgt tgacttcgat tcgtcaaaca gaaccaggaa aatacaccga
     6241 tcggattttc ggtatggaca accgaagttt ctatgtacca aaagatttat agcaaaaatt
     6301 tatttttttc attcaaaaca aaaaaagcga gacataagtc ttcgcttttt ttgttttctt
     6361 ttattttgat gaatcagttg tttcttcagt tgaagattct tttgttgaat cagttgattt
     6421 tgtgtcagaa ctctttgttg aagctgtagt ttcacttgag tctttcgtac ttgatgaagt
     6481 tgttgtgaat gcactcaaca cattttcaaa ggcatcatct ttgattttta catttgcatc
     6541 ttttaattct tcaccgatta ctttagttgt gaatgcattg tcacttagtt tagtttcagt
     6601 agcgatatct tttagttgat ctttgtattt atccatgtca ttgcctttat tttggttttt
     6661 caccattttg acaacgtagt attctgtcgc ataagaagta ggatttgttg tagtaataac
     6721 atcggagatc tcaccgtctt tcaatttgaa agctgcttct tttacttctg caggaatagt
     6781 tgttgtcgtt gagtcgaatt taactttacc gccatcttct tttgtctctg tatcagttga
     6841 tttgtctttg gctaatttag agaaatcatc tccatcatcc gctgattttt tcacatcttt
     6901 tgcttcatct tcacttgata atttgatgat ttgtgcttct acttctggat ggaaagattt
     6961 ccaagcagtt ttcaaatcgt catctgtaat atctacgtga gctttcaagc cagcttcaaa
     7021 agctaaattg ttacgaatat attctttata agtatctttc gtatatccag cagcttctaa
     7081 ttgtgattca aaagtatcac ctaatgattt cgcttgtttg tcgtattctg catccacttg
     7141 cttatcggtt actttatcgc catatttgtt attgaatact ttataaatga tcatccgttg
     7201 tactaaggat tggttcgatg attcaagttt tgcttcatca tagaaatcag atacagtgat
     7261 cgttccgcct ttcatcgttg cgatatcttt attagtatcg cctgaacaag ctgctagagt
     7321 taaaacagcc aacgcactag tagctgccaa aataattgat ttttttttca ttaaaatttg
     7381 cactcctgta attagttatt atttttatat attaactata ccatatccca tttcctttaa
     7441 aaacgttgtc gtggtagttt caaacaaaat tcaaaatttc atcacattcc taggaaatac
     7501 gcaaactttt ctcacttata tagttaaatc tgttgagaaa ataatcatta ttatatttgt
     7561 tcaggatact ctggcagatc agcttttagt ttttctactt gttcattgat ttgtgtgata
     7621 cgtggttcgg cttggaattt aaaatcttcg atatcttttt tgattgcttc ttggaaagca
     7681 ggaatcacag attcagctgt ttcttttgtt tcgatcaatg cgcttttaaa atgattcagg
     7741 ctgttattta aatcatttgt cagagttgtt gcttcttcca attcttcgat cagtttcttt
     7801 cttgtttcat tcccgctcct gggcgccaat aacagacctc cgacagtgcc agcagcagct
     7861 ccaaataaca gtcctttgaa aaagttttta atcatcgcag gacacctgct ttacgattgt
     7921 ttcttgaata gcttttagtt cttccgatcc ataactatct tgatgattga caaagtgaat
     7981 agaaaaatca tcctctttgc tgtagcgagg gactaaatgg atatgtgaat gaaaaacaga
     8041 ttgataggct agttcacggt tgttattcaa gatattaaga cctttcattt ctggaaaagc
     8101 tttttccaat gcttgagcaa tcttaggcac acgcgaaaaa acctctcctg caagttcggg
     8161 atcatattca aaaatatctg ctacatgacg tttaggcaca actaatgtgt gtcctttcgt
     8221 tgcttgagag atgtctaaaa aagcatagac cttgtcgtct tcatatattt tatagcttgg
     8281 gatttcttga ttgatgattt tgcaaaaaat acagttttcc atataaaaca tcctttctat
     8341 aaagaataaa tacttcagct taactttacc ataagttaaa gctattgtaa ggaaaaaaac
     8401 aaaataccgt cattttcttc gtggtataat aaataaaaat aaatggcgga ggaaaaagaa
     8461 tgagtttaat tatcgatcat gtcacagggg ggtacggaca tctccctgtg ttaaaagata
     8521 tcagtttcga tgtacagcct ggagagatag tagggttgat tggactgaac ggagcaggga
     8581 aaagtacgac catcaagcac attatcggtc tgctggaagc ttcaaaagga acgatagaaa
     8641 tcaatcatct atccttaaag aaaaatacgg aagaatatcg caaacaaatt gggtatattc
     8701 cagagactcc ttctttatat gaagaattga cattgagaga acatatcgaa gtcactgcga
     8761 tggcctacga tatacctatg gatatagcaa tgaaaagagc agaaaagttg ttggagactt
     8821 ttcggttatc taatcgtctt gactggttcc cagctaattt ttcaaaggga atgaaacaga
     8881 aagtgatgat cttatgcgcc tttttgatcg agccttcttt atatatcatc gacgaaccat
     8941 ttttaggctt ggatccacta gctatcaatg cattgcttga attgatggta gaaatgaaaa
     9001 aagaaggagc cggtattttg atgtctacgc atattttagc tactgcagaa aaatattgtg
     9061 atcgttttgt ggtcttacat aacggagaga tacgagcaga cggttctctt gagatgttga
     9121 gaaaagaatt tcagctgccg gattcttctt tggacgaaat ctatattgct ttaacaaagg
     9181 agcaggcaca tgagtagttt ttttcaaaaa cgtttagcaa gacatcaaaa gaaaatgatg
     9241 aaatatatgc gttatgtatt gaacgatcat tttgttttag tttgtctttt cttgattggc
     9301 ggtgtgggat tatattattc taattggttg aaaaccctgc agccaccgtt tgcaattgga
     9361 gggctcataa tctctgtatt ttggatgctc tgtttattcg tgggtaagat ggctactttt
     9421 gcagaggcag cagatattgt ttttttactt cctaaagaaa aagaaatgca aacctatttg
     9481 gaacgagctt ttcgctattc ttgcattttt ccgttgatct ttttgatatt ggcatgcgga
     9541 ttggccatgc cattagtggt ggttagtacg gagcaatcct tttcgatgtt tttcgtctat
     9601 ctgatcatat tatggagttt gaaattcagt catctgcaaa tcaagagagc agaattgttt
     9661 cgactagatc aacaagttat tcgttattgg aaattaggct ggtttttttc ttctctgatc
     9721 tttttgtttc tatcatttta ttggctaata tgggcaggaa tagcaggtgc attagtacag
     9781 gcaagtctat attactggtt tttgtggaag caacaagaaa aaggattgga ttgggagaaa
     9841 atggtgcatg tagaagaaca taggttgcat cagatctatc aatttatcaa tttattcaca
     9901 gatgttcctg aaattacggc aaagatcaaa agaagacgct atttggatcc tatattgact
     9961 catattaaaa gagaatcaaa aaacacttat ctttacttgt ttgcaagaag attggcaaga
    10021 ggttctgatt ttagtggtct ttatttccga ttagtaatta taggtgggtt attgattgcc
    10081 ggagtagtcg acttttattt tagtctgatt atcggtttct tatttttata tttgatcggt
    10141 ttccaactgt tacctttagc gaaccagttc cgctatatgg ttctcgttca gctttatcca
    10201 atccataaga atcagaagaa gcaggcgatt cagtatctac tcacatgggt attaattatc
    10261 gcgtcggtta tttttggttt gattgctgca gtcgtattag atgggcagca gcgatgggtt
    10321 ccgctagcgg cttatttgat tgttactatg ctctttgtta aactatatgt accaactcgt
    10381 ttgaagaaga tgtcagactg aaaacaaagc tgtgtagggt aaaaatgaga atgaaaaata
    10441 gagcgttgac agtaagaatg ctgttcgttc tatttttttt gagaaaagct ggttttttga
    10501 atggcaatta aatgaaaaag aacgtatatg tgcttgacgt gtagtgttca ggcgactaga
    10561 ataataagta ctgcaaaaca aagagtaaga ggacgggaga atgcatgatg gagtttcagt
    10621 tagaccaaga gtggcggtta cgtcccatca aaggcgacac aggaaaaaca tacataggca
    10681 tgcgtgatga ggacaaagtc tttattaaac gaaacacgac tccgatgttg gctgctcttt
    10741 caagggaagg aattacacca aaacttgttt ggacaaaacg aacggggaat ggcgatactt
    10801 tgacagcaca agagtggctg gaaggtcgct tgctgactcc taatgagatt ggtcaaagaa
    10861 acgacgtgat tgatgttttg taccatttac atcattcaaa ttctcttaaa accatgctga
    10921 cccgtatcgg tggtcgtgtc atgacgccgg agaagatgct gcaaaaatat gaaaaagaat
    10981 taccggaaga actccagaaa aatcaatttc tgcaaattgt ccatcgtttt cttcgtgagc
    11041 agatcccgtc aatagataag gaaaacttat cagtagtaca cggagatgta aaccatcgta
    11101 attggttagt atgtaaaaat tatttatatc tagtcgattg ggattcaatc atgtttgcag
    11161 accctgcggt ggatattgca acgattttag gaaattatgt gccactgtct agctggaatc
    11221 agtggctgat cagttatggc atacgcccga ctgacgaaat gcttgaaaaa tttcattggt
    11281 atgcggccat gaatttgctc caagaaatca ccagatattg caaacgtgaa gatcatcgac
    11341 ggatgaacga agaaatttta caattaaaac gaattttcag tggctgaggt ttggcccaaa
    11401 ctctgcggag atttggccag acctttttaa ttagaggaaa ggaatggaga taaataatgc
    11461 gtgtccgaaa tcgtccggga gcagcggaaa tgttagcggc tcacccgaat tttgtaatta
    11521 gtgatccaac attgtggaag ggaaaatgga atgaattgtt tgaaaacgat catccaatcc
    11581 acattgagat tggtatgggg aaaggccagt tcatcactgg aatggcaaaa gcccatcctg
    11641 aaatcaatta tattggagta gaaatgcagg tcagtgttgt ttcgattgca ctagacaagt
    11701 tgatcgaaca accgcttcct aacctgaaac ttctacatgt ggatggatca gcgttgacag
    11761 agtatttcgc tgacagcgaa gtagatcaaa tctatctgaa tttttccgat ccatggccaa
    11821 aaaaacgtca tgaaaaacgg cgattgacat ataagacttt tcttgctgta gatgaacaga
    11881 ttcttcgtcc aaatggagaa atccatttca aaacagataa tcaaggattg tttgagtatt
    11941 ctctggcaag tttttctcaa tatggcatga tcctcaaaca ggtatggtta gatttacatc
    12001 aaagtcaatt tgaaggcaat attatgacgg agtatgaaga aaaattttct tcaaaaggtc
    12061 aacgtattta tcgagtagaa gctcaatttc aagataagac caaaaagaaa agtctgtgaa
    12121 actaactttc tgctttcata aaaacattaa tatccataaa taaatcccag aaaatgaaca
    12181 ttacagatgt aatgtatttt ctgggattta tttgatttaa aatgtattta tttcatcggt
    12241 ttttccacaa ggtggaatca attggaagcg agaaaatgaa aataatcctt tgtcggtgat
    12301 cttcaattcg ggtatgacag ataatgttaa gaaagaaagt gtcaaaaaag gatcaaaggt
    12361 tttagctgct cctagttgat gtgctttagt tattaattca ttcaactgtt catagacgat
    12421 cgaaaaaggt tcctgtgtca tgattccgcc tataggaaga gaaacacaag ctatttcctg
    12481 ctgtttgttg acaacggtca tcccgccacc tttttgaatc aaaagattag cagcatacag
    12541 catatcctcg tcgtttgtcc caacgacaac tagattatgc gagtcatggg caatcgttgt
    12601 cgctatcgct ccttgtttca gctgaaatcc tttcactatg cctaatccaa tgtttcccgt
    12661 ttgatggtga cgctcgatca ccgcaatctt taattggtct ttttcgattg aaggaatgaa
    12721 tcgttcgcct tgtcggtcca ctttttctac caaatcttta gtcactagac tattcgggat
    12781 aatttcgatc acatgggctt gtgaagaaga aagaagcagc tctaacgaat gtggatttaa
    12841 tggttgagcg tttagttttg gcagacaaca cgtatatgaa tttgaatgat cagcaaataa
    12901 atggtcttgg agttgcccag attgaacaac taatgttccc ttatagaaaa cttcatgaat
    12961 tggcagcttg gtaagatcgt ctgttaagaa gaaatcagct tgatacccag gggcaatcgc
    13021 acctagtgtt ttcaaatcaa aacattctgc tgcattcaat gttgccatct gaatggcttg
    13081 taatggatcg attccaagtg caatagcttg acggacgata tgatcgattg atccttcttt
    13141 tactaaatca ttgatcagtt tatcatcggt gacaaagaag catcttcttg aattttcagg
    13201 tgtgatcgcc ggtagtagcg atgccagatc ttttgcaacg gtcccttctc gaaccattaa
    13261 atacatacca agatccaaac gttctttagc ttcttttgca gttgtagctt catgatccgt
    13321 ccgaatacct gctgcaggat aaacatttaa ctcttccatg ccgataccag ctgcatgccc
    13381 gtcaattttt ttcttatgct ggtgcatcaa ttggatcttt tctaggatgt ctgtttcatt
    13441 atttgctact gcttgatagt tcatgacttc agctaagcct aaaacttcgg gtttttgtaa
    13501 aaaaggggct aatttttttg catttaaatt tgcaccattg gtctcaaaag gggttacagg
    13561 tacacaagaa ggtagcataa aaaagatatt catgagtgtt tgtcttgcat cttctatcat
    13621 aaactcaaga cctgtactcc cagcaatgtt tcctatttca tggggatctg tcactacagt
    13681 agtaactcca tgaagcaagg atacttttga aaattcgctt ggtgataaaa gtgagctttc
    13741 gatatgcaca tggccatcga tgaatcctgg cactagatat tgcccattag cattatgtac
    13801 gctttttcct tcgtattcac cgattcctac gatcattcct tcgcagattg ctacatcttt
    13861 ttccatgatt tctttcgtaa agacgttgac gatcttagca tgcttgatca ctaggtcagc
    13921 aggctttttt ttacttgcta cttcgatata tttccttaat gttgtttcca atggagtgcc
    13981 tcccaagata aatttttata agtataacat aaattcggtt tttgccaata tttttttgta
    14041 aattcatttt atttgaaaca aaaagatcaa aaagacgtat gttttttgtg gaggggagaa
    14101 taatggaaat aaaacgatta tcggatcaaa tgataagtga aagttttgcc aaacatgccc
    14161 aagacgtata tatattgcca gcttcagaag tattttacat ctattttcgc tatggaaaaa
    14221 aacgaacatt ctggaagaaa gtctcttcgg cagatggaca gcaactgatc tcaagattta
    14281 agtatttggg acagatggat atcggagaaa aaagaaaagc tcagttaggt gcatttactt
    14341 attctttaga aaaacaggaa gttcgtctgc ggttgtcttc tgtaggagat taccttcaac
    14401 gagagagttt agtgattcgg ctattatacg gtacttttga aacaccccat cgttgcttta
    14461 gttctcgaga ttttgcaact attttacaga aaaccgtcag acgtggatta taccttttca
    14521 gcggaccagt cggatcaggc aagacttctc taatgtatcg gttggctttg gaagaaaaat
    14581 tgcaagtgat tactatcgaa gatcctgtag agatagaaga accgtttttt ctgcagctac
    14641 agatcaatcc gaaaatagca cagacttatg atacactttt gagactcgca ttacggcatc
    14701 gtccagactt gctaatcatt ggcgagataa gagatgaatc aactgcacat gctgcggtaa
    14761 gagcagcact aacagggcac cgggtttttg caaccgtaca tgcacgcaat cttgaaggta
    14821 cattggtcag aatccatgaa ctgacaaaga aaaaagaaga gctatctgaa tgtttagctg
    14881 gtgtcattta tcaagaactt ttggaagatg ccaatcacca tccttctgtt ttatggagtt
    14941 atcaatttat ggaggaagaa tcagtaaaaa aatcatggga ggaaagttat gaagaagctc
    15001 aggaaaatat ttggcagtca gaactattct aaaggattaa caagaagcca gcaaaaccag
    15061 tttgcacaaa ccatgggaga actgctttta tctggtttta gtctgcaaga atccctttat
    15121 ttattactca cgatccgttc gtttccacct gttattttgg caaatatcca acatcagcta
    15181 aaggaagggc aagcgtttag tgaggtactt tcgcaaatag gatatggagc agagcaactg
    15241 gtacagatcg agttagctga acgtcatggg aatctgccga caactttgtt ggaaattgcc
    15301 aaacagtttc ggcttgttga aggatttcgc aatgatttga aaaagctgct tgcatatccg
    15361 atgctattgc tcaccttttt gctaggtatc ttgtttagta tgcggttgtt cgttttgcct
    15421 cagcttattg gttcaggaat ggtcatgcaa gagcattggg gtattcagct gatacaagtc
    15481 tttcattggt atgttctact attcatccta gcggttactc tattggcttt actagtaagg
    15541 tatcgtctga tgaagttgtc tcctgttgat cagagtgaat ggataagcag acaattattg
    15601 attggaccga tatattcctt gtatcaatcg gcttatttgt cactagagat tggaaagctt
    15661 tttcatgaag gtttcgaatt aaggcaaatc atagtctgct taaaggaaac gaaacaagaa
    15721 agtctgattc agcatcttgc ctctaagttg attcaaggat tggaggcagg tatgtcattg
    15781 gctgagcagt tccagaatta tcgttttcta tcagaagaat tcagtaaaat tgttttacag
    15841 ggagaggcaa agggaagttt aggtaaagaa ctgatttttt acagcgaatg gacaagaaaa
    15901 cagcttttca aacgtcttca tcactggatg cattttattc agccaatcat ttttttgggc
    15961 gtagcggctt tgattttatt agtttatgcc gctgttttat tacctgttta cggaagcata
    16021 gaggaggttt tgccatgaaa aagagaaaaa tatcttatta tagcggtttt acattgatcg
    16081 aaatgctaat cgtcttactg atcatcagtg tattagtgtt gttgttcgtc cctaatttgt
    16141 cgcgttatag gaatcatgta gaccaagaaa gtcgtgaagc gatcatccag ttggtagaca
    16201 cacaaaaaga gctctatgcg cttcaaaata atggaagagt tcctactgtg gaggaattgt
    16261 tgaatgaagg ctatatcaaa cgagaacatg cagaaatcta tcagcggcct tgaaggtaag
    16321 gttttagcat caggatatac gttgtttgaa tcactcttac tgattttatt acttacaacg
    16381 atcctttctt ttccagttct cgcattttct gcatggaaga atgaattggc agtctatcaa
    16441 tttttcggcc aatttgaaaa acgaatctat tctacgcaaa aaatcgctat tgtgaatcag
    16501 atccaaacag gcttttattg gaatagtgaa gagaatcaaa tcatttttca tgttccgaat
    16561 ccagataaaa taaattggga agtattagat attcctgatg agattacctt gaaacgccat
    16621 gcttctatta cttttgctgc tagaaccggg aatgaaagtt cactaaaagc ttatcaattt
    16681 tattgggaag aaaaagagcg gacgattacg tatcaattcc agatagggag tggtcgctat
    16741 acaaaaagaa ttgaataaaa caggatttgt tttgttggag tcccttacag cgcttatgat
    16801 cgcttctgtc tgtgtctact tagtgagctt tggccagctg tttttgcttc aggcagaaaa
    16861 gaaaagtggg gaggaactgc tatttattcg aatgatttat gaagatatca agacgcagcg
    16921 gatgtatcac aaaagaccag agcgaaggga agaaatgatc ccatacgata tccaaattgt
    16981 cgataataat ggagtaatcg aaaaagtgtt tgtcaatatg gagaaagaag cgatcagtat
    17041 tgaaaaaaca agtaattcca gcatttacgc tgattgaatg tctaattgga ctgatgatat
    17101 tgagcagtct attgctcaca ttcaatcttt tgattcagca aaccatccaa gtaagtgaat
    17161 ttttgcagcg taaagatcaa aaagagtggc taatattttt agcacaatta gaagaagaac
    17221 tcaagagcag tcacaatgtc tctgtgaaaa atcagcaact gcactacacg atcgaggata
    17281 aacagtatat catcgaaaga tatcaggcaa tgatacgtaa aagaagaact tccggcggac
    17341 atcaacctat gttaacaagt atcactgagc ttcaattatt ggaaaaagaa cacacaattt
    17401 ctttttatgt acactttgaa aatggagaag atggatatgc catatggaca aaaaacgatc
    17461 agtagaaaat gttataaggg ctctatttta ttttctgtct tgcttttatt tcttttatgt
    17521 acgtttttat tgatggcagc attagaaagc taccgtttgt caatggatct taatatacga
    17581 atcaaaaatt attatatagc aaaaataatg aagcagatgg ctttatcgga acagtctacg
    17641 cttgccgaaa gttcggaagg agttttttac tacacaactg gatctgtaac atatcagtgg
    17701 gtacaacagt ccctattctt agaggtggaa gtctcaccgt ttatctttcg gttcacagaa
    17761 gaagtaaaaa atgatacaga tactagtaca gaatgatgga atgttcgtga aaacgccctc
    17821 ttttctgtta taacactgtt tttaataaaa aaatgtttgc cgtttcacaa ataaaaaaca
    17881 gtgaaaacga ttgaaatttt gtcaattgtt cgatagaatt aaacaggtga aaaaattgtt
    17941 ataatatatc tagaaatgag gtgcaccatg ttaccagaaa aaatggaaca agggtttaat
    18001 caaaacctgg aagctattca gcttttacag aatgcattgg gaacttcctt tttagaagcc
    18061 tatgtcgaaa atgcagaaaa tttaatagat gattatcaag tacgtgtggt ggatggagtg
    18121 ccgacaaaag agacaacgca acggatcaca gctctttatg aagagttgaa gaaactttct
    18181 ttcgagccag aagaatggcg cagactgtct caattacttt tattgaaggg cagccagaca
    18241 gaacatttgc aggcgaacca tcaactcact cctgatagta tcggtttttt atttgttttt
    18301 cttattgaac aactatacac aaataaaaaa gcaccggtta agattctgga tattgcggca
    18361 ggaatgggca acttgttatt aacagttctt ttaaacctat cgaatgcggg gtaccaaaca
    18421 gaaggaattg gtgtggatat tgatgataca ttgttggctg tcgcagcttc tacaagtgat
    18481 ttgacacaag caaatgttca atactttcat caagacgggt tgcaggaatt attaatagat
    18541 cctgtcgatt ttgcaatcag cgatttgcca atcggttatt atccgaatga cgaaaaagca
    18601 aaagagtttt taacaagtac cgaagaaggc catagttatg cacatcattt attgctagag
    18661 caatcaatga aatatgtgaa gccggatggt tttggtttgt ttttgatgcc gagtggattt
    18721 ttagaaacgg atcaaagtga agaaatcaaa aaatggttta aagaagaagg ttatcttcaa
    18781 ggaatgattc aattgccaga tgaattgttc cgtaataaac aatcgcaaaa aagtattttg
    18841 atcttacaga aaaaaggacc acaagcacaa caagtaaaag aagtcttgct tgtgaaactt
    18901 gcttcattaa aagaaccaga gaaggtgacg gaatttttca acgagtttaa aaactggaaa
    18961 tcatctgctc tgtaatcatt caacgagaag gagagtcata tgtctaaaac aattgcaatc
    19021 aatgctggga gttcaagttt gaaatggcaa ttatatcaaa tgccagaaga aaccgtagtt
    19081 gcgaaaggga tcgtcgaacg tatcggttta caagattcta tttttaccat caagtacggc
    19141 gataatcaaa aattcgaaca aatcatggat atcgaaaacc acgaagtagc agtaaaaatg
    19201 ctgttagatc agttgattga actgcaaatt ttaagctctt atgatgaaat caccggagta
    19261 gggcaccgtg ttgttcacgg aggagaaact tatggggatt cagtagtgat cgatgagaaa
    19321 gtaatggacc gcattgctga attagcagaa tttgctcctt tgcataatcc tgcaaactta
    19381 atggggatca aagcgtttaa aaagatttta cctgacattt tgagtgtggc tgtattcgat
    19441 acatctttcc actcaacaat gccaaagcaa aattatttat atagcttacc ggtgtcttat
    19501 tatgaagatt tcaaagtaag aaaatatggc ttccatggca caagtcatcg ttatgtgtcg
    19561 gaacgtgcgg caaaattatt gaacaaaccg atcgaagaac taaaaatcat cacttgccac
    19621 ttaggaaatg gtgtatcgat cacagcagtc gatggaggta aatccatgga tacttctatg
    19681 ggattcacac cattagctgg ggtgacaatg ggtacacgtt caggtgatat cgatccagct
    19741 gttctcccat atttaatgga aaaattagag attgatattg atgaaatgat caatgttttg
    19801 aacaagaaat ctggtctgct aggcctaaca ggattgtcta gtgatatgcg tgatcttgaa
    19861 aagaactatg aaaaagaaca tattcgttta gcttatgaca ttttcgtgga ccgcatccga
    19921 aaatacatcg gcggttatgt gacaacgatg aatggtgttg atgcaattgt ctttactgct
    19981 ggtatcggcg agaatgacgg acatgtacgt agtgaaatca tcaaaggtat gtcttggttt
    20041 ggttgtgaaa tcgatccagc gttgaatgaa ttgcgtggtg aagaagtaga tatctctaca
    20101 aaagaatcaa aagtaagagt attagtgatc ccaacagatg aggaactaat gattgcccgt
    20161 gatgtggagc gtctgcgcgg ctaagccaaa gcattcgtta ggataaaaga tgaaacgcat
    20221 gcaagaggga attcttgcat gtgttttttt tgcggagaag accgcaaaat ggtaatttaa
    20281 cttcaatttc ccttcttttt tacaggatct tcttagggaa ttttgcttgg aaaagtggtc
    20341 aaaagggaaa agactggcat tttatttatt gattttcagg aaaatcccaa tattttattt
    20401 tcattcatct ttataaggga cattacatat gtaaaaagaa aaaacatttt tagatcagcc
    20461 tcgtgggctg tcgactttat tcttcgcttt atgtttagct agaaaaccga tccgaaacat
    20521 tcattgatcg aataataaaa acttgatttt ccacctgtac tttgcctgaa tcgtgaaagc
    20581 acaggtatga aaatcaagtt ttttgttgcg aaaaaacgtc ctagtcaatc agttggccga
    20641 gcggctggcg gctgatctgc tcctgatcaa taacgagtgc ttcttggaag tgttgctgca
    20701 aaaagtagcg gtcatggctg actgctagga gcgttccttg atagtcttgc agcatttctt
    20761 caatttcttc tcgagcatag ctgtcgaggt gattggttgg ttcatccaaa atcaggacgt
    20821 tgattttttc taaaaagagt ttcagcaacg ccaaacggat tttttcacca ccggataaat
    20881 ctttgatccg tttacccaca tcgctttgat aaaagccact tttggctaat tgccgtcgag
    20941 cgacttcttc gtttccagtc aatgtgatgg cgtaagccag caaacggcta tcgggatcgg
    21001 caaactgcag ctgctgcggc aaataaccga tttgcaagct actacctaat ttgatggtgc
    21061 caccgtaagg cttttcctca ccgagtaata atttgagtaa ggttgatttt cctgcaccat
    21121 tgtcgccgat gatggctaaa tgatctccac gatagactgc aaaactgctg tctttgaata
    21181 gtacttgatc agcgtactgc tggtgcaagt tttgaatgat gaaaacttct ttgccagatt
    21241 ttccaccatt agacaagctt tgcagccgat ttttcggggg aggtggcggt ttgacgagtg
    21301 tcagtttcgc caggcggcgt tccagttctt tggctttttt gaagaaggac tcattgtctc
    21361 cttcatgtgc ccactgacga aaacgacgaa tcatgacttt caaccgctgg acttcttttt
    21421 gctgcagttc gtaatttttt gtcagctcag ccaagcgagc ttctttcaag actcgaaaac
    21481 ggctgtagtt tccgggatac tcaatcaatg caccttcttc cagttcccat gtttttgtgg
    21541 tgacttgatc gagaaattgc cgatcatgag aaacgaccag aaccgatttt tttgtattct
    21601 gtaaatagtt ttccaaccag cgaatactgt taagatctaa atgattggtc ggttcatcga
    21661 gtaaaagtaa atcggcatcg gctgctaaaa ttttggctaa agcgacttta actcgttcgc
    21721 ctccgctaag ttctgttaac cgtgcttcct gacggtgtgg aatccctaag ccttgcaaga
    21781 tcgctgcaat ccggtcttct aatacgtaac cgcctagttc ttcaaagcga tgctgcagct
    21841 caccgtaacg ggccagacac ttctctaagt ttgtatctgg ttctgtcatc aatgcttcgt
    21901 agcgactcat ttgctgtttg aggtcctgta tctcagcggc agaatggagc aagtagtggt
    21961 tgacggtcgc ttcggaaact gtaagttctt gttcgaccgt cccgatcttt aagccttttt
    22021 tgcgactgat aacaccgctg tcgacacctt ctctgccggt caagatttgt aaaaaggttg
    22081 atttgccagt tccgttgata ccgactaagg caattttttc accagcttca atttgacagg
    22141 ataaatcctc aaataatgga ttcccgccga ttgttttttt aatagaaatt gcttgtatga
    22201 tcatgatctc tctccttgag accactcaaa aaggccatgg ttatccatgg cctgtgttat
    22261 ttaaactcag attatcatga gaaaaatacc ttgagatggc cattgatttt acgtgaattc
    22321 aactgttttg gacaaacttg tcccgtcaac agcaactgta aaaccaattg catggctaaa
    22381 tgcgatatgg tatcgttggt aattttcatt acttgttatt ttagtcatgc gcatcatagt
    22441 attttccctc cttcgtgtag ttgtcttttc cagtgtacct gaaagtgtca gaaagttcaa
    22501 ctagcgctga catttactta atatttatcg atgtgtaatt ctgtcagaga gcttttttta
    22561 tctgactgag ggtaatgtct cgtggaccac atcattgtat tctgagctaa accagcgttc
    22621 aggcgaaatc atatggtgtt tgataaaaaa ctttgtctac atgacttcct tttgccattt
    22681 gcttaatacc gttgcattaa acagctcttc tctttggaaa tctcaccaac atcgcgttca
    22741 ggagtatcgt tgtggttgca atggcaagcg gtagcctttc atcaattctt gaatgattta
    22801 ccgaatgtag cacttgcctt ctcgcggtac ccgaacccga aataaaattt tagtttggcg
    22861 ataaaatcgg tatccgccat cgatacttca tattttttcg tatcagattc atcggaaact
    22921 tccacattga cgaaccaata agctttggca tgcttaggtc gttttaaacc acaccagggc
    22981 gactaatcgc cctggtgttc actttttttt attttacttg aactcattga ctgttttccc
    23041 tttattttaa acattataaa gaccgatgag tgcttgccgc gtcttttgtt tttatcacgg
    23101 ttttttgtgc aaaaaaacct gccgatagtt ggcaggtcgt ctacgtgtta agctttggtg
    23161 tggtctttag ctggcaattg gttttctaaa tcagttcgga caacaagcac atcgcaagct
    23221 gcgtttctaa taacatattc agaaacagaa ccaataaata aacgttctac agcattcaat
    23281 cctgtggctc ctaacataat caaatctact tgattatctt ctgggatttc tctggcaata
    23341 atttgttttg gtgagccata ttctacgaca gaggttacat tattcaagcc agctttcttc
    23401 gcattgcttt cataatctgc caatgtttgc tttgccattt cagtagcttg ttctgcaagc
    23461 attccatcaa aggatgaaac ggtttggaaa gaacgtgtgt caatgacatg tgctaataga
    23521 agttctccgt tatttcggat agctacattg accgcctttt taaaagctaa ttcagcttca
    23581 tcagaaccat ctacggcaac catgattttt ttgtattgtt gtaacataag cattcactcc
    23641 tcaagtcaat cgtattgtac tcttttattg tagaacactt tagggaaaaa gagaattatt
    23701 tactgctttg gttcagcaat tttttttgca aatcggatac tgaaggtggc agaaacaata
    23761 attacgatca gtaaaaagac caaggcaata aagcgttgat tgaaaaaagc tgttaaaata
    23821 cccattacgc ctaaaacagc atatgcagct ccgtaaaatt gtaggaatcc ttgattttta
    23881 tcatttttgt tgatcaatac aaaaaagata tcctgtttat taaataaata atagctaacg
    23941 aataataata ctaaagtggc gataatcatt aaaatcctaa tcatgaacaa atcctccaaa
    24001 ataagcaaca aatagaaaaa gcaatttgcc aagagcaaat tgctttattc tttaaaagat
    24061 ggtaatctcc gttaatgccg ttgtttgtcc tgtagtattg atcccgcgaa ttcaagcagg
    24121 tgggtcccat ggtcgtagct tcgaactacc aaatgataag gcatgttacc agcagtgaca
    24181 caagacgggt cccaagatat caataaaaat gttcggtcaa cacacaaaga ggacaattcg
    24241 aacatcacag atttcccacc tctatagtag catatgaatt taaaaagagc aatgagagag
    24301 ctcgcagaaa cagaaccgtt ttcttgtcta gttttttgga ggatgctttt tccactcttt
    24361 tatacggtaa tactgttgac ccagagcctg ttcatatttc cctgtatctt ttggctgata
    24421 atactgagca ttcttcagtt tatctggtaa atattgctga ttgacccaag cctgatcaaa
    24481 atgatgagga tactgataac ccacgccacg gttgagtgat ttcgcacctt tgtaatggct
    24541 atctctcaaa tgatcaggaa catctccagc tttgccctct cgaatatcag caagtgctgc
    24601 atctaatgcc atgtaggcag aattggattt tggcgacaag caaagatcga cgacgacgtc
    24661 tgctagtggg atacgtgcct caggcaatcc caatttttca gcagctaata cagcgttcac
    24721 tgtacgagcc gcagcagcag gattacctaa acctatatct tcataaccga taaccatcag
    24781 acgccggcaa atacttgcca gatcacctgc ctcaactaaa cgggcgagat aatgaagtgc
    24841 agcatccaca tcacttccac gaatcgattt ttgaaaagcc gaaataacgt cataatgagc
    24901 atctccattt ttgtcatggg taagagcttt tctttggaca cattcttcaa tgatcgacag
    24961 tgtaagatga atccttcctt ctttatctga aggagtcgat agtgtagcca gttccagccc
    25021 attcaatgca ctccgcaaat cgccgttcgt tgcacgcgaa aggtgaagaa gagcatcttc
    25081 gtctaactgg attgcttgtt gtccaaggcc gcgttcttta tcccttaaag catgttcgac
    25141 tgccaactgg atgtcttgtt ctgttaatgg tttgacttca aagatctgtg tacggctgcg
    25201 gatcgctgga ttgatggtaa tataaggatt ctcagtagtc gctccgatca agatgattcg
    25261 gccactttct aaatgaggaa gcagaaaatc ctgttttgtt ttatctaatc ggtgtacttc
    25321 atccaataag aggatcactg taccactcat ttttgcttct tccgctacaa cttgtagatc
    25381 cttttttgaa tctgtagcgg cgtttagcat gcgaaatgca taattagtag agccggcgat
    25441 cgcacttgcg atactcgttt ttccagtacc aggaggtcca tatagaatca tggaagagag
    25501 catgcgagca tcgaccatgc ggcgtatgat ttttccttcc ccgactagat gctgctgacc
    25561 aacgacttca tcgatcgttc gaggtctcat gcgataagcc aatggctgtt gcataggatt
    25621 ttcctccttc ttgtttttac gtcccttaat tatatcatat ttagcaagat gcctagaaag
    25681 aacagccttc tgttgttttg ttttcatagc ttatccaact aatattgtgt atgataaagt
    25741 aggtgagaaa aatgacggat aaacaaaaga tagatgaatt tttttggaat aaaacgacgc
    25801 cagaagtggc acgggattta ttggggatgt atttggagca tgacacacca gaaggaagat
    25861 tagctggata tattgtagac gcggaagcat acctaggtcc agaagacgag gccgcccata
    25921 gctatggttt aagaagaaca ccgcgtgtgc gggcaatgta tgaaaaacca ggtacgatct
    25981 acctttacac gatgcatact catcggattt tgaacatcat tactcagcca gaagggattc
    26041 ctcaaggagt aatgatacgt gcaatcgaac ccgccgcaat gattgatcaa atgagtaaaa
    26101 atcgtggcgg aaaaactggt ccagatatca gcaacggtcc gggaaaatta gtggaagcat
    26161 tagcaattcc tcaagaactt tatggtcagt ctatagcaga tagttcgtta cgcttagttt
    26221 ttgagaaaaa aaagacacca aaaaagatca atgctttgcc tagaatcggt atcccaaaca
    26281 aaggtgtatg gacagaaaag ccgttgcgtt ttgttgtgtc gggaaatcct tatatctctt
    26341 tacaaagaaa aaaccaaatc gagaaagatt ggggttggag gaaagaaaat gaaaaagaag
    26401 gatctattaa catatttaga tgaaataatt gaaaaacaag tgacagacta tgatgtagct
    26461 ttagattggg atacaaaaaa tcatacgatc gagatcgttg ttcgcttgtt tgcagaaaat
    26521 aaagcacaat ttgagattga tgatgcagaa gggatcgttt cgcaagaacc aattatcgaa
    26581 tttgaagacg gcgtacttct ttttaatcct cagaaatctg tttttgatga acgcaattat
    26641 ctagcagtaa tcccttatga aggaaaaaaa gggttggcaa aatcagtagc tgattcttta
    26701 gtggaatatc taaatgaagt attagctcaa gggcaaagcg atttgcttga ttttttggat
    26761 gaagacgatg acgaagctgt attcgagctt cactgggata atcagcaact agcagaatta
    26821 gtagaagtaa aacagcaaaa tgaagcagat acttatttac cgtacccaag ttattaagga
    26881 gtgacagata tgaaatggaa tgaagtaaaa gtagaaactg aaagtgaagc agtcgaagca
    26941 gttgctaata ttttgatgga ggcaggggcg agtggtgtcg cgattgaaga ttctttagat
    27001 gttgaacatt ttcagtcgga tcaatatggt gagattttag ataaaaatga ttttacatcg
    27061 ctgaaagaag gcgcactagt catggcttat tttccggaaa cgactttctt accggaaatc
    27121 ttgcctttta tcaaagatcg tatcacacaa ttacctgagt ttggtctagc tattggaaaa
    27181 aataaagtaa cagttagtga agtagaggaa agcaactggg caacagcctg gaagaaatac
    27241 tatcatccgg tgcgtattac gcgaatgctg acggttgcgc caagctggga aaactaccag
    27301 acagaagatc ctctagaaaa aattatcaca ctagatcctg gtatggcatt tggcacaggc
    27361 actcatccca cgacttcctt gacattgaca gcactagaaa cagtcttgcg tggtggtgaa
    27421 acattgctag atgtgggaac tgggtcgggc gtgctaagta ttgcagcaaa atatcttggt
    27481 gcaaaagatg tctatgcctt tgatttagac gaagtagccg ttcgttcggc gaaagaaaat
    27541 atggatatga atgaaatagc caaagatgtc catgtatcag ctaacgatct tttgacagga
    27601 atcgagattg aaagtgatgt aatcgttgcg aacattttag cagatatcat cttattgatg
    27661 atcccagatg cttggcgttt actgaagcaa acaggcacgc tgatcgtttc aggaatcatt
    27721 gaagagaaga agcaaatggt tctggatgcc atgttagaac aagggtttat cgtggatcaa
    27781 attttccagc aaaaagactg gtatgcaatt attttgaaaa aaccagaggt ggaatagatg
    27841 cagcggtatt ttttaaaaga atcatatgaa tcaaaagact attttgtttt agaaggggaa
    27901 aactatcacc acattgtacg ggttatgagg atggaacccg aggatgaagt ttttttggca
    27961 ttcaatgatc aaatagccat tgttgcagaa atcacggaga ttactgaaga ggctgtttat
    28021 ctgaaagaaa ttaaaaaaga agaaaatcaa aaggaactgc caagttcgat taccatagcg
    28081 agtggctatc ctaaagggga aaagctggat tggatcgttc agaaatccac tgaattagga
    28141 gcgcaagctt ttcttggttt cccggcatca gcctctgtcg ttaaatggga tgcaaaaaaa
    28201 cgtatgaaac gacaacaacg gcttgaaaag attgctcaag aggcagcgga acaatcccat
    28261 cggcagatcg tgccatcagt agagttattg gaaacgaaac aagatttatt tgagcggcta
    28321 gatgattatg acgtggtctt ggttgcttat gaggaatcag caaagcaagg cgaaaaatca
    28381 aatgcagcca aaattcttag tgaaacaaaa ccagatagtc gaatcttagc tgtctttgga
    28441 ccagaaggtg gattatcccg cgatgaagtc gattattttg tagaacacaa agggatactt
    28501 tgtggattag gaccaagaat ccttcgtaca gaaacagcac ctctttattt attaagtgct
    28561 gctagctatc aatgggaatt aatgaatcct tctttcagct aacgttcttc attaataaaa
    28621 gagtatcgac agaaagaatt gaaaaaatag tcaacaattt gtataataga aacaattatt
    28681 tatacaatgg atacgaaaaa tcgtttgaaa aagcttttaa aaagcgaaca tttccgtaaa
    28741 aaaacgtata actgcacgga ttttgggaca attatcaaac agatatttgt cccgattccc
    28801 gttttaccga aaaaagaaag ggggatcgat tcctgtgaca aaagaagaaa ttttaacggg
    28861 acccggtgtc ataaagctcg ttagtcaata catgggtccc gaacatgtag catttgttga
    28921 gaaagcatgc gaatacgcga ctgctgcaca tgacggacag tttagaaaat caggcgaacc
    28981 ctacattatt catcctatcc aagtcgcagg tatattagca gatttaaaaa tggatcccca
    29041 tacagtggct acaggcttct tacatgatgt tgttgaagat acagaaatca ctttagaaga
    29101 tctgagagaa gaatttggcg atgacgttgc tatgttagtg gacggcgtaa ccaaattagg
    29161 gaaaataaaa tataaatccc acgaagagca gctagcagaa aaccaccgaa agatgctgct
    29221 agcaatggct caagatttac gagttatcat ggtcaaatta gctgatagac tacataacat
    29281 gcgtacgttg aagcacctgc gagaagataa gcaaagaagg atcgctcagg aaactttaga
    29341 aatctatgcg cctcttgcac atcgtctagg gatcagccgg atcaaatggg aattagaaga
    29401 tacagcactt cgttatctaa atccaaaaca gtattaccgt atcgtccact tgatgcagac
    29461 gaagagagaa gaacgtgaaa aatacgtaag tggtactgtt gaagatattc gaatagcgac
    29521 agaagagctg gggatttttg cagaaatcta tggacggcca aaacacattt attcaatcta
    29581 tcgtaaaatg aaagatcaga aaaagcagtt caacgaaatt tatgacttgc tagctattcg
    29641 agtgatcgta gattcaatca aggattgtta tgctgtatta ggagcaatcc acacaaaatg
    29701 gaaaccaatg cccggcagat ttaaggatta tattgccatg ccaaaagcta atatgtacca
    29761 atctttgcat actaccgtga tcggtccggc aggaaatccg gtagaaattc aaatccgaac
    29821 acaggaaatg catgaaatcg ctgaattcgg ggttgctgca cactgggcct ataaagaagg
    29881 aaaaaatgaa aaagtagaac cagatggtat gacgaaacaa ttaagctggt tccatgagat
    29941 actcgaactt caagacgaaa gctatgatgc ttctgaattt atggaaggcg taaaaggaga
    30001 tatctttagt gataaagtct acgtcttcac accaaaagga gacgttactg agttaccaaa
    30061 aggatccgga ccattggact ttgcatacag tatccataca gatatcggta acaaaaccac
    30121 tggtgcaaaa gtaaatggca aaatggtgca gcttgattac aaattgaaaa acggagatat
    30181 cattgagatc atgacttctc caaattcatt tggcccaagt cgcgactggt tgaaattagt
    30241 tgctactagc aaagcaagaa ataagatcaa acgtttcttc aaagcccaag atcgagaaga
    30301 aaatgtgatc aaaggccacg aatccgtggt caaatgtatt acagatctag gatttacgcc
    30361 taaagatatt ttgacgaaga acaaactgca agaagcactc gatcgtttta attatcaaac
    30421 agaagatgat ctctatgcag ctgtagggta tggagaagtt agccccttga cgatggccaa
    30481 tcgtctgact gaaaaagaac gtaaagaaca aaaaatcgag cagcaaaagc aagaagcaga
    30541 agaaatcatg aatcagccga aaaaagaacc tgacaaaatg aaagtacgtc atgaaggtgg
    30601 cgttgtcatt caaggggtag aaaacttact aattcgtatc agtcgctgct gtaatccgat
    30661 tcctggtgat gatatcgttg gttatatcac taaaggcaga gggatatcca ttcatcgtcg
    30721 agattgtccg aatgttcagc ctgacaaacc aaatgtagca gaacgtttga ttgaagtcga
    30781 atgggaagat acatcgaata cacgaaaaga gtatgatgca gatttggaaa tttacggcta
    30841 taatcgttca ggcttattga atgatgtact tcaaacagtc aatgcgctaa cgaaaaatct
    30901 caacagcgtt gaagcacgga cgaataaaga taaaatggcg acgatccatt tgacggttgg
    30961 tatccagaat ttatcccacc taaagagtat cgtggataaa atcaaagcag tacctgatgt
    31021 ctacagtgta cgccggacga atggatagga ggacagatat gagagcagtt gttcaacggg
    31081 taagtaaagc tgctgtgtca gtcgatcagc aagaaattgg aaaaattggc tacggcctac
    31141 ttgttttatt aggcattcat gaaaccgata cgcaaaaaga tgtggactat ctggtaaaaa
    31201 aaattgcaca aatgcgtatt tttgaagatg aacaaggaaa aatgaatatt agtgtagaag
    31261 atgtgggagg acaaatttta agtatctctc aattcacact gtttgcggat acgaaaaaag
    31321 gaaatcgacc aagctttgtg gaagccgcac gaccagaaac agctattcct ttatacgaat
    31381 cattcaatga aggaatcaga agtcgcggca tcacagtcgc taccggacaa ttcggagcag
    31441 atatgtcggt ttctctcgtc aatgatggac ctgtaacgat cattattgat tctaaaaaca
    31501 aataaagtaa tctggttttc actagtaaaa actatgaaac acgtcgctta agttagactg
    31561 ataaactcta acttaagtgg cttttttgtc tgcaaaaagc gcttcttttg tcagcagtcg
    31621 gaaaaaaagt taagcttaaa ttatacaagt tattttttat aggaggttgc tgaagatgaa
    31681 agaagtacca gtagtagata tcaaaatcac agatttaaaa aaattgtatc aaaaaggata
    31741 caacatgttg gaggagttac gccatgaagc ggacgctccc gtcgtcaaag caaagatttt
    31801 caataaagaa gctatcacga tctacggatc atcagcagca aaagtatttt atgatccaag
    31861 gaatttcaaa cgaaaaggtg ctatgccaaa attagtattg aagacacttt ttggtcaagg
    31921 tggagtacag actttggatg gagctgctca tcaccatcgg aaaaatattt ttatggatct
    31981 aatgacaccg gaaagaatgg aagattatca tcgtatctta gataagaatc tgacacaagc
    32041 acttgaagca cagcatggtc aatttgaact atttgattta agtaagatgg ttttctttac
    32101 atctatttgc gagtgggcag gtatcaattt atcagcgatt tctaaagatg aggtcgaaaa
    32161 attagcagaa tatcaaatct ctatgatcag cggaacgttt acttctccga ttgatcacat
    32221 aaaaggtgtc gaaaatcgca aaaaatcaga aaaatgggcg caaggcttga ttgaagaagc
    32281 tcgacaaaat cctgtggctg gaaaagaaaa tgtggcatta tatgcttttg ccaatgccac
    32341 agatttagat ggtcagcttt tacctctgga agtggcagct gttgaattat tgaacatcat
    32401 ccgtccaacg gttgctctaa ctgtgtgggc ggcattgatg ggacatgcac ttttcagtag
    32461 accagatttg tatcagcaat taaaaaatga cttttcgacg ttacaagatc cgtttattca
    32521 agaaatgaga cgctattatc ctttcttccc aatgctacct gcgatttcgc tgaaagaagt
    32581 agaagtagat ggttatcgta taccagaagg cagttgggtt attttagatt tatatggaac
    32641 agaccatgat gaacgaacag ttgaagcgcc agattccttt atgatcaaac ggtatgtagg
    32701 gaaagcaaaa gatatttcct ataaagaaga atatgagatg attgcacaag gcgggggaaa
    32761 ttttcgacaa atgcatcgct gtgcaggaga atggatcact cttcatagtc tacgtgtgtt
    32821 ttccgatcag ctagtaaata agtttgagtt ctctgtacct gaacaagatt ggacgattcc
    32881 attcaatcag tttccgactt atccgaatag ccgagcgcta ctttacaaga attagattag
    32941 cataaactta tcgaaaaaaa ggaagatcaa acagtgctga tcttcctttt ttcatattac
    33001 tataaattga taaggtcaat tgatcaaaat ccacgaaatg cttcatcaat ggtttgataa
    33061 tcttcattgg ataaatgcaa atctaaagct tggacattgt cagatacttg ctctggacgc
    33121 ttagctccag gtataactac agacactcgt ggattcttca tgtaccaagc taaaacaagt
    33181 tgcgcaggag tggcttggta tcttttagca atggggcgaa gtacatcgac agcggttaaa
    33241 atttctctga aacgttctcc ttggaaatct ggatttcttt ttcgaggatc tccttcacca
    33301 aattgttttt cctcaccaag ttcatatttt cctgtcagca aaccggaagc aagaggaaaa
    33361 tagggaacaa aactgatttt gtttttttca agataaggga ataattcttt ttcagcctgc
    33421 cgatggatca aactgtattt atcttctact acatcgacat atccatctgc attcgcttct
    33481 ttcaattgtt ctaacgtgaa gtttgacaca ccgactgctc ggatttttcc tgcttctttt
    33541 aattcgtgca atgtagcaac tgattcattt tttggtgtgc tttcatccgg aaagtggata
    33601 taaaaaatgt cgatgtaatc agtttgcaga cgttttagtg catcttccac cgattgtttg
    33661 agaaactcag gagaattatc aaatgttcgc cctttatttg gtacatgagc agcttttgta
    33721 gcgatgacga cacgtgagcg atcatattct ttttccttca gtacctcgcc aatcagttct
    33781 tcggaacggc cgtttccgta agcataagcg gtatcgatca aattgatccc gctattcaaa
    33841 gctgtacgaa ctacttgttt tcctgtctca tcttccaaac cgtcaaaaag attatgtcct
    33901 ccaacggcat ttgctcctaa tccaagctgt tctgcgtaga cttgtgaatg tccgattctt
    33961 atttctgcca tagctgattc ctcctttttg tctagtctaa aacaaaatac caaaaagctg
    34021 aactaaaacg tttttgtgag gggaaatagt cagatatctc ttgactttga gactggtttt
    34081 tagtaggtta taagtaatat cgaatgtcaa tgaaagagcg agtaagtttt tgaaacttta
    34141 caagagagga tcatcgaggc tgaaaatgat ctaaagtttc attagcctaa agacactctg
    34201 gagatggacg agtgaaaagc cgtcccgcgt acgagcgtta ttcgtaagag gaaagagaaa
    34261 tctttcaaaa ttaggtggta ccgtgtatga atttcattca cccttgttca tgatgaacaa
    34321 gggtgatttt tttatttaca tagctaagaa agggagagaa aactatgagt ttccaaagac
    34381 caaaaggaac aaatgatatt ttgccaggcg aatcagaaaa atggcagttt gtcgaagaaa
    34441 cagcacgttt attattcaga gattatcagt ataatgaaat gcgtacaccg atttttgaac
    34501 actatgaagt gatatcccga agtgtagggg atacaacgga tatcgtttca aaagagatgt
    34561 atgattttta tgacaaaggg gaacgccatg tgacgcttcg accagaaggt acagcaccaa
    34621 tcgttcgttc ttttgttgag cataaattgt tcggcccaga gtatgcgaaa ccgttcaaaa
    34681 ctttttatat gggaccaatg tttcgctacg aacgccctca aaaaggacgg ttacgtcaat
    34741 tccatcaaat cggagtagaa gcatttggat cagaaaaccc tgcaactgat gtggagagca
    34801 tggtgatggc acttgatttc ttcaaacagt tggggatcac gcaaatccgg ctagtcatca
    34861 attcattagg tgataaagaa acgcgtcaag cctatcgtca agcattgatc gactatcttt
    34921 taccttttga atcagagctg agtgaagact ctaaacgccg ccttcatgaa aatccattac
    34981 gcgtattgga cagtaaagac aaacgagatc aaaaatttgt ggcagaagct ccatctatct
    35041 tagattatct aagcgagcct gctcaaaaac attttgatac cgttgtttcc atgctggatg
    35101 cattggctgt tccttatgaa atcgacagta atatggttcg cggactagat tattacacac
    35161 atacgatttt tgaaatcatg agtgacgcac caaaaatggg ggcacaagca acgatttgcg
    35221 caggcggacg ttatgacaat ctagtggaag aactaggtgg tccttcaaca cctggcttcg
    35281 gatttgcaat gggtatcgag cgattactct tgactatgga ggcagaggaa gtagttatcc
    35341 ctgcatttaa tgagttggat gcttacgtgg tcgcactcgg agacgaaaca aatatcgaag
    35401 cattgaaagt ggtccaagcg attcgaaact ttggtttttc agctgaccgc gacttcatga
    35461 accgtaaagc aaaagcgcaa tttaagacag cagataaagc gaatgccaaa ttagtattgg
    35521 tgatcggtga agatgagctt gctagtcaaa cgattaatgt caaagcaatg gcaagccgaa
    35581 aagaaaaaag ttttccatta gaagagatat atgaacattt tgatgaagtc tatgatgaaa
    35641 tgactttatt cgagtaggag gaaaaaaata aatggcacaa agaacgatct attgcggatt
    35701 agtttccgaa caacaattag aacaaacagt tacattaaaa ggatgggtac aaaaaagacg
    35761 agaccttggg ggagtaatct ttatcgacct acgtgatcgt gaaggaatcg ttcaaatcgt
    35821 ctttaatcct gaaatcaaca aagaagcatg ggaaatcgcg gataaatgtc gcagtgaata
    35881 cgtgatcgaa gtgactgggg aagttagaag acgcggagaa aatgcagtaa atcctaaaat
    35941 ggccactggt gaattcgaag tgattgcaag tgaaatcgtg attttgaatc aagcaaaaac
    36001 cccgccattt caaattgaag atgatcaagc aatcagtgac gaaatacgtt tgaaatatcg
    36061 ttatttggat ctgcgtcgtc caaaaatgac taaaaacatc aaattaagaa atgcgacaac
    36121 aaaagcgatt cgtcattatt tagatgataa tgactttctc gatatcgaaa caccttacct
    36181 agggaaatct acaccagaag gcgcaagaga ctacctagtt ccttcacgtg tccatgctgg
    36241 acatttctat gcgttgccgc aatctcctca attgtttaaa caattgctga tgaatgctgg
    36301 attcgaccgt tattatcaaa tcgttcgttg tttccgcgat gaagatttac gtggagaccg
    36361 tcagcctgaa tttacgcaag tagatattga aacaacgttc ttaacagcag aagaaatcca
    36421 aacttacaca gagggattga ttgcgaaggt aatgaaagaa gttcgcggta tcgaagtcac
    36481 attgccattt cctcgtatga cctatgatga agcaatggct cgctacggca gcgacaaacc
    36541 ggatacacgt tttgatatgg aattgatcga tctaagcgat acagtcaaag aagtagaatt
    36601 caaagtcttc caaatggctc ttgaaaacgg cggtgtcgtg aaagcattga atgctaaagg
    36661 cgctgcagat cgctactcac gaaaagacat ggatcagtta ggtcaatatg taggacaatt
    36721 cggagctaag gggcttgcat ggctgaaagt agaagaagac ggattgaaag gtccaattgc
    36781 taaattcatg ggagaagcaa cagaagcaat cattaaagca acagatgcaa aaccaggtga
    36841 cttgctgatg tttggcgcag ataaaagtga aatcgtcgct gctgcattag gtgctatccg
    36901 gacacgttta ggaaaagaat taggactaat tgatgaatcg aaattcaatt tcttatgggt
    36961 aactgattgg ccacaatttg aattttcaga agaagaaggt cgatatgtct ctgctcacca
    37021 tccattcacg atgccaaaag aagaagatat cccgttattg gctgaagacc ctgcaaaagt
    37081 ctatgcagaa gcttatgata tcgtcttgaa cggttatgaa ctaggcggag gttctatccg
    37141 tattcatact cgtgagcttc aagaaaaagt actagaaact ctaggcttta caaaagaaca
    37201 aatggaagaa caatttggtt tcttgttaac agctttagat tacggattcc ctccacatgg
    37261 cggtattgca ttaggattgg accgttttgc aatgttatta gccggagaag ataatattcg
    37321 tgaagtcatt gcctttccta aaaacggaaa agcagcagat gtgatgagtg atgcaccaag
    37381 tatggtttcg cctttacaat tgttcgaatt gaatattgat gtaacgaata tagaagaata
    37441 gccgataaaa aggtaaaaag gatttgtcga atacgcttct tttgacaacc ttgatttaat
    37501 tgaaaaacac tttataatga agccataaca tataaagcgg ggcttttcca tgaaaaaaac
    37561 attcgaaaat tgggcttatc atgattacac gaccaagctt tcggtatcta tcgtttatgc
    37621 gttgatcgca tcagtcgcat tgaatttctt ttatcagcca ggacatattt attcaagtgg
    37681 tattactggt ctagctcaga ttttgacgac tttgtcaaaa tcactgatag gattcgaagt
    37741 accggtatca acaactttgt atttactgaa tatacctttg tttgtattgg cgtggttaaa
    37801 aatcgggaag aagtttacaa ttttcacttt tatcacagtc actttgacct ccctttgtat
    37861 ccatatttta ccggaaacag tcctatctac cgatccaatc atctgtgcgt tgtttggggg
    37921 ggctgtgatg ggactaggta ttgggctagc gttgagaaac ggcctatcat cgggcggtct
    37981 agatatcgtg agtatcacga ttcgtaaaaa aacaggaaag tcgattggtt ctatttcgat
    38041 ctacttcaat gcattgatcg tttttgttgc cggaattcta tttggctggc aatatatgtt
    38101 ttacagtacg ttgtctattt tcgtcagtgg aaaagtaact gatgtcgttt atactaaaca
    38161 aaagaagatg caggtaatga tcgtaacgaa acatccagaa aaagtagtaa atgaaatcca
    38221 aaactgtatg cgtagaggga tcacgatcat caatgaagca gaaggtgctt ataagcatga
    38281 taagcagaca gtattgatga cgatcgttac acgatacgaa ctgcctctac ttagagaagc
    38341 aatgaaagct tctgatccac aagcttttgt aagtattgca gaaaacgtcc agatacttgg
    38401 tcgtttctat gaggatggca tttagatcga gtttgacaaa aattcatgaa atactgctgt
    38461 agacagacgt tcgtttgtct gcagtttttt tctaccatag tagaatcagc aaagaaaaac
    38521 tgctttttta tttgaaattt tcttaaagtt gaaaaaaagc atgtttattt ttttaaattt
    38581 atgggatgat agaaaaaaat agtagagaaa ggacacgatt ctacttgcta ttttcactta
    38641 atacccgtat attacgaatg aaaaaagttt atgaaaagtt ggaatattga atggaaaaac
    38701 aaaaaaggtt aaaaaacagc cgctacatca ctgggtttga tgggctccgt tcattagctg
    38761 tggtgggtgt tatcttctat caccttctgc caactagtat gaaaggcggc tatttgggcg
    38821 ttccgatttt tttcgtcgta tctggttatt tgatcacgga tctgctgcgg caggaatggg
    38881 aacaaaatgg aaaaatcaat atttggcaat tttatgtcag aagaatgaag agactctatc
    38941 cggcacttgt ttttatgctt gtgacagctt cggcttatat cactttgttt cagcgagggc
    39001 tgttaaacaa tcttcgagga gttgtggtca gcagcttact gtatgtcaac aactggtggc
    39061 aaatcaataa cggtttatct tatttcgatc gatttgctaa tgagtcaccg tttacgcata
    39121 tctggtcttt agcagtagaa ggtcaaaact atttggtttg gccgatcttg tttgtattgt
    39181 tgatggtatt tgttcgtaaa agaaaatgga tcttttatac tgtgttaggt acatccttcc
    39241 tctccgccat cttgatgatg atcttgtata caccaggagg cgatccaacc cgtgtttatt
    39301 acggtaccga cactcgtctg ttttctatat ggttgggaag tgcgcttgcg tttgtttggc
    39361 caagtacgcg tttaaagaaa aacatcccga aacaagcgaa aaatattctg aatatcgctg
    39421 gaggaatctc gcttttggca ctgattcttt gcttcttctt tttagatgat cattacaatt
    39481 tcatctatta cggaggaatg ctcctagtga gtctgttatg cgtagtgcta gttgcagtga
    39541 cagcacaccc cggagcaagt ttgaatcgat ggctgacaaa tccagtattt acttggattg
    39601 gcaaacgaag ctatggcatt tatctgtatc agtttccagt tatgattttt tatgaagcaa
    39661 aggtgactga tattgccgat catgttttgt tgcatacttt agtggaaatc acattgattc
    39721 taatcatcag tgaactttct tatcgatatg tggagcgtcc gctagcacgt tttgattatg
    39781 gtcgtacatt ccaagtgatg aaaggatggt tcagcaaacc gatcatcagt aagagcaaac
    39841 catgggttgt tccaggcaca ttacttgtag caattgcact cgttggtttc gttacggcac
    39901 cgaaaaacgc tgtaacagcc gatcaaaaac aactgcaggc aaaaatcgct gaaagtaaaa
    39961 aattagcaga agaaaccaga aacaattcag aaaacaccac tagttcggtt gaccaagcga
    40021 tccttgataa gtacgagttg tccaaggcac aagggaataa ggcacaaaaa ttagaactaa
    40081 cggcatttgg tgattcagtt atgttggatg ctgcaacgga tctacaagaa ctttatccaa
    40141 aagtagtggt agatggagat gtcggacgac aattatatgc cagtgtaccg tacattgaaa
    40201 aattaaagga acaagatttg ttgaaagaca ctgttctgat cggactagga acgaatggct
    40261 cattctcgga agctcagttt gatagtgtga tggatgcaat cggtgatcga aaagtatact
    40321 gggtcaatgt ccgagtaccg acgaagcgct ggcaaaatga cgtgaatgcg atgcttgaac
    40381 agatgacgaa aaaatacgac aatatgacgc tgattgattg gtacagctac agtaatgacc
    40441 atagtgactg gttttatgat gatcaagtcc atccaaatcc tgaagggatg acacattaca
    40501 ttcacttagt cagcgaagcc ttgctaggag gaagttcaag tacgaacagc agtgagacaa
    40561 acgtgacaga atgatagcta caaaaaactt caggcaaaaa catttgtttt tgcctgaagt
    40621 ttttttatat ttaccgtgtt tttaacattc atatagattc aggaagcaaa acggttgagt
    40681 gtgtctgtaa ataacgttct ttttgttttc gggtgagttt tttgaatgca gcttctgctt
    40741 ttgttgcttc gcttcttgaa gaaaatactt ctgcatggat catcttaaca ggtcttcttt
    40801 tttgaagacg agtatattta gcaccagtac cattgttatg ttcctctaat cgtctagaaa
    40861 gatcggttgt atatccacca taaaatgtct gatctttaca gaataatacg taaaaataat
    40921 gttcatttgc catagagcat ctcacgaatc tctgcagtgt attctccatc catattgtaa
    40981 gtgatcaatg gtggagcgac tttgaatccg tctaatttgc cttctttgat tccttcaact
    41041 aacaaaatat ttgcctcttt tccaggtttt gggtaaacaa attggatcct tttaggtgca
    41101 attcgatagt cttccatgac ctgaatgatt tctaagaacc gatcaggacg atggaccata
    41161 gtaaagcgtc catttgtttt tagtagctta cttgaaatat cgatcacttc ttctaacgtc
    41221 gtatgaatct catgacgggc gattgccagg tgtttattag ggttcgtttt atttgttggc
    41281 agccctttga aataaggtgg attacagacg actaagtcac aagaattatg tcgaacgaca
    41341 gataagctgt ctttcagatc gatggtgtgg acagtcattt gttcatttaa atggttaagc
    41401 gcgatactac gtcttgccat gtctgctaga cgaggttgaa gttcgatagc gtcgatagcc
    41461 gcctgggttc gtttacttaa aaaaagtcca actgcgccat ttcctgcaca aaggtcaaca
    41521 atcttccctt ttttaggtac acgggaaaag tgagcaagca gcacagcatc taaagaaaaa
    41581 gaaaacactt tggaactttg gataatcttg atatcttctg cgtataattg gtcgattcgt
    41641 tcgtcttcgt gaagcatgga ttccctccaa aatgaaaaaa atagtcgtct gtattatact
    41701 atttttatta aaaagaacca aggtggcttg tcaaacctct attttttatg catactatga
    41761 ccataagaag ggaaaggaag agactatgtt ttatcgattt atgcgcgggg tagttcgagt
    41821 actattagcc ttagttaatg gaaatgcccg ctatgagaat aaagaagttt taccgcaaga
    41881 tgagaattac atactagttg ctccccatcg tacttggtgg gacccattat atctggcggt
    41941 agctgcagca cccaaggaat tcagctttat ggcaaaagaa gaactgttca aaaatccagt
    42001 tctgcgattt atattaactc gatccaatgc ttttccagtt aaaagagaaa atccaggacc
    42061 aagcgtcatt aaaacacctg taaagatttt gaaatcgaca aatttgagtt tgatcatgtt
    42121 tcccagtggg acaagacatg ctacagaact taaaggcgga atggcattga tttccagaat
    42181 gtctaaagcg aaaatcgtgc cagctgtata tcaaggtccg ttgacacttg gggatctgtt
    42241 caagcgtcag agagtgacag tgcgtttcgg cgaaccaatc gacttatcag atatcaagaa
    42301 aacggataaa gaaggtatgg cggagatcga acgacgaaca caagcagctt ttgacaaatt
    42361 ggacaaagaa gtgaaccctg atttcaaata tgaagtcaaa aaaaaataaa atgataagtt
    42421 tatgcgtggg cggtcttttg aatctactgt cctgttcagt tcagactttt tcaatgaaaa
    42481 cgagggagag acgtcaagtc tgccctcttt ttgcgttcca atatgtaaaa tagaagacag
    42541 gtgtcatgta atggatcaaa gtgttataat aattagaagg acattttttg aggtgattga
    42601 atgcgttttt tacatacagc cgattggcat atcggaaaaa aactacaagg ttatgacttg
    42661 attgaagacc agcgtcatgt actatcttct atactagata tcgcgaaaga agaaaaagta
    42721 gaggcaatcg tgattgccgg agacttatat gataggagtg tcccagctgt tgatgccgta
    42781 gaattataca atgaattgat ggtcgattgg aatttaaagg aaaagatccc gatttttgct
    42841 atatcaggaa atcacgatag cagtacgaga ctttcagcgg gtacgccatg gttcagttat
    42901 tcgaactatt ttttgcgaac acagctagca gaagcatttg aaccagtcga gtttaaaaac
    42961 gtacaatttt tctttcttcc ttactttgaa ccaattgcag cgagattata ttttgaagat
    43021 gacaatatcc gaacgatcaa gcaagcggta gccaaggtga tagataaaat gcaggagcta
    43081 tttgattcag aaaaaaaaca agtattgatt agccattttt ttgtaatggg aagtgtaaaa
    43141 tctgattcgg aaacgaaaat cgaagtaggc gggttggatt cgatccctgg tgaactactt
    43201 acaccgtttg attatgtagc actaggacat ttgcataatc aagctgcttt gagacaggat
    43261 aatgctcgct atagcggttc cccattgaaa ttctctttat ctgagatcaa ccaaaaaaaa
    43321 ggcgtatgga tcgttgacct gacaacaggc ctggagttga attttaggga gatcgaaccc
    43381 ctgcatgata ttgaagaaat aacagcgagt ttcaaagaat tgctggatcc tgccttttat
    43441 cagtccgtca atcgggagaa ttacatctat atctatctca ctgatagaac gatcatcccg
    43501 aatatgatga accagcttcg gcaaatatat cctcgtattt tggggattga acgggcaaac
    43561 ggtcgagcag aacaaacaaa gcgcaaacga aaagtactag aaatgaaaga tcctcaaaaa
    43621 ttagcagaag cattttttag tgaaatgacg gaagagcagc taactgcaaa ccaagaaaaa
    43681 tggctcggag aaacgttgca agaaatcatg gaaatggaat gatcaagaat gaaaccgaaa
    43741 aaattacaac ttaaaaattt tggtcctttt atcaatgaga ccgtagattt ttcacgtttg
    43801 acagaagcac cgcttttttt gatcagcggg aagacaggag ctggcaaaac gacgattttt
    43861 gatgggatca ccttcgcact ttttggtgaa acttccggaa gacttcgctc tggaaaagag
    43921 atgcgttctt tgtttgctac accagacgaa gaaacaagcg tgactttttc ttttgaacat
    43981 cagcagatga gctatgaaat cgaacgaaaa ccagaacaag ttttagcaaa acgaaaagga
    44041 aacggaacaa aaaaacaggc agccaaagta acgttgacca tttttgatgg gaaaggaaaa
    44101 gaaataaaac aaatcacaaa acgtacagaa gcagatcagt tgatcagaga actgatgaat
    44161 ctcgatgcga aacagttttc tcaaatcgtt ttactacccc aaggagaatt ccgtaatttt
    44221 ttggtttcat caagcagtga taaagagact gttttacgtc atttattcgg tactcaattt
    44281 ttccaacagt tcaatgagcg attaaaagaa aaagcaaaac aacagcaaca aaaattggat
    44341 catttagagc aagagctgca tcttctgcaa aaaaggtttg ttttagtcaa agaagaggaa
    44401 ccagcagcag ggtttgaagc cgttttagcc caatggacaa accatcaggc aatactcgaa
    44461 aaacaaatca cggaagaaaa agaagctcta acggaacttc aggaaaaaca aaagcaacta
    44521 gaaaattcct actatcgttt tgaaagcttg aaaaaaagtt atgaagaaaa aacgatatta
    44581 ataaacaagc aaaaggaatt agctgctcaa aaagacgaaa tagaggaaaa gaaacgatgg
    44641 attgggtatt atgaatttac gcaacgatta gtcgaaccaa tccagcgcct acaagaaata
    44701 aaagttgaaa aaatagaact gtcacaaaaa agtagtgagc aaacaaagaa actagcgatg
    44761 actacgcaga attatgaaga gtggcaaaaa aatgaagcaa accgcgtacg ccgacaaaca
    44821 aaaatcaaag aagctgctca aaaactgcaa aacaaacaga tgatggtgcc aattgtcgaa
    44881 tccttacgta gtaaaaaaca agacgcagaa caattaacaa tttcattgga taaagaagaa
    44941 ttgaatgccg agaagctgta tcaaaatctc gctatctatc aggaaagaac tcgaattctt
    45001 caagaaaatt tactggatca ggaaaaactg caagaagatc gtcttgcttt tggacagtta
    45061 aaatatctag atgaaaagca gcaagaaata gaaaaacaaa aagcaaaaga cactgggtcg
    45121 ctcgcacaga taagagaaga actcaaaaaa gcaactgaag aaataacaaa aaatagtcag
    45181 ctattgaaag aacagacaga acaagcagaa cagctgaaaa gccaatgggc aaagcagcaa
    45241 attgctcgtc ttcagctttt tttgcgtcca ggggagccat gtcttgtttg tggatcaacg
    45301 gaacacccca tacaacaatt aaaacacgaa cagccaaata aggaagatat cttaaaagta
    45361 gaacaacaac tggcagaagc tgagtctgct gtagaaagaa ctcagcaaat cattgccaaa
    45421 agtgaagcac atgaaaataa tcttcaacaa caattatcag atttagaaca aaaaatcatg
    45481 gcaacgaata tacaattggc tgaacaagaa gaacacttgc aacaggcttt gaaaaaggca
    45541 tttcctgaga taacagaaca aaaaacaaaa acaactcttg tagtaatcga acaatcttta
    45601 gatagacgaa aaagcaagat ggccaatgca agaatagagc tggaagaaat aagacaacaa
    45661 gcagaaaagc tcgaacaaca attagctgtc tacaaacagc agcagacaga aaaaaataat
    45721 cagctccagc aactgcaagg agaaatcaaa agtttagaac aacaattgca agatacggat
    45781 agtaactgtt tagaagagga gatacgacga cttgaaaaac agttagaaga agactcgaat
    45841 caactagctg ttgagcagaa agcaggagtg caattgttgc aagatcttca tacgcttcgg
    45901 acacagcttg atcttcaaca tgaacaaata gaaaaaatag atgaaaaaat agaaaaggaa
    45961 caagaaagaa tagctaaaaa gttagaaagc cagtcgtatt tttcaacaat tgaagaaatc
    46021 tgtgcatttg cacaacagca agcacaatat aaagaaaacc aacgtacagt tacttcttat
    46081 catgaagagc aattagtgac agctgaccgg ctgcgtcaat tagaaaatat ccagctaact
    46141 gagacattcc cagatacaga agagatcagc caacagttag aagaaataag acgtatgatc
    46201 gaaataaagc aagaaaagat atacggttta caagaacaaa aaattagtaa tcaaaaaatc
    46261 tacgatgaat gtctttcgat ttatcacaca agccagacga aattagatga gcttacgcaa
    46321 ttacagcagc tttcgcaaac attcaacgga gaaaatccta agaagactag tttggaacgg
    46381 tatgtgcttc aggtttatct tcaagaagtg ttacaagtag caaatgatca tctccaacgt
    46441 ttaacgaaaa atcgttatca atttgagcta gcggatacca ttggcagtta tcgagggaaa
    46501 accggattag aaatcaatat ctatgatgat caggcaggta tgtctcgaag tgcgcatacc
    46561 ctgtctggcg gtgagagttt tattgcagca ctttctttag cattagctct tgccgatgtg
    46621 atccagacac aagctggtgg tgtagcaatc gatgcattgt ttattgatga aggatttggg
    46681 tcattagatg aagaagcttt ggaaatggca atggaagctt tagaaacgat cgaaagtgaa
    46741 ggaagaatga tcggcatcat tagtcatgta agagaattga aagaacgagt attacaacaa
    46801 ataagaattg atacagaagg tagcggacaa agcaaaatac gctatcaact tggataaaaa
    46861 gggagattgg taactatgaa atggagtatt ccagaaaaag tcattgcacg tggacgtcaa
    46921 tacttgcaag aaggccgagt gttatcggtt gtccctgacc aagaagaaaa cgtgtggcat
    46981 gcagaagtct tgggcagtga attgtatatg gttgatttgg atggtacagc aaaagagata
    47041 gattactgcc aatgtcccta ttgggaggaa cataaatatt gtaagcatac agttgctgtg
    47101 gaactttatt tacggtcgaa aaatctatct cgtatcatga aaaaagacca gccaatgcta
    47161 gaaccggtaa aagcaacaag tgagggagaa atcattgcaa aaggtttttc tcgtctaaaa
    47221 acacaaaaca atcctcaagc ggtgcaacct ttgattattg aataccaagt agaaacgatt
    47281 gagactaatc agtatcaccc agagctttct attttggcac tttacttgcg tatcggttca
    47341 ttggcatcac cgaaaaaaac atatatcgta aaaaacatct atgatttttt acaagcttac
    47401 acagaaaaag aaacttacac tgttaataaa cagtaccagt ttcgtctaga taaacgggcg
    47461 tttcaaaaag aagatcaaaa aatactcacg catcttgcag gaagtgctca gacgcatcaa
    47521 ttattaggta cgaacggctt acaagtcaaa ggaaaactag ataaaagata tctgcttctc
    47581 ccagtagaac aagcccgctt cctgttagag cagatgaatc agactacacg tttgcatctg
    47641 cagataaatg aacaaaacga tcaaggaata caattttccg atcaaaacaa acctttatca
    47701 ttcaaagtgg aaaaatttgg agaagattat ttgctgcaag cattgaatga ttttgatttt
    47761 ttctttatgc attatcagtg gggagttatc caagggacat tttattctct gacgaaatat
    47821 caacaaacgg tttatcaaac ttggaaacaa ttgattcgcc gattggagaa accagaagta
    47881 gtgttcaaga aaaaagaatt accgtctttg tttaaagaga ttatccctct gctgtcagag
    47941 atcggcgacg tagctattgc ccctgcagta gaagaggaag tagcagatat ccccgtcgaa
    48001 tttattttct ttttccgaaa agcaaaagga aaaatccaag ctcgagtcga tttcgtctat
    48061 ggcgaagtca tctattcgac tgacccgaag catgaggtct cgacagaaca ggcttttcag
    48121 gtgttacgtg acacagtaga agagaaacga gtacttgatc tattcagaat gtatcgctac
    48181 cagaaaaatg aaactggtta tgaacgtcca ttgccaagcg gggaagaact atatgccttt
    48241 ttccgcacag aactatctgt cttccgtcag tttggtgaag tcagacttgg aagaaaattg
    48301 cgagagttgt atttagatgc gcataaacat caaccgaaaa tcgaagtaac cgagaccggt
    48361 tcatggctcg atattcgatt cgatgtgaca gggatagagg agcaagaaat cgatcatgtc
    48421 ctgcaaagct tgctgagaaa tgatgctttt tatacattag aaaatggtca ggttctttct
    48481 tttgattcag aagaatttca acaaacaagc caagtgttgc aacaattacg ggaatcgata
    48541 cgtacagaag aaggaacgat ccatgtacct aaaaatcaag gattgatcat tcaaaatcaa
    48601 ttggaaaaaa gcaatgctac ttttagtgaa tcgttccaaa cgatggtaca agatctcatt
    48661 catccagaaa gataccaggc acagcttccc aaaggattga atgcaacgat gagagattat
    48721 caaaagcaag gttttcgatg gttgaagatg ttaggtcatt atcagtttgg cggtatttta
    48781 gccgatgaaa tgggacttgg gaaaacacta cagacaattg cctttttact ttcggaaaaa
    48841 gaagaacgga aaagcttctc tgctttgatc gtagcgcctg cgagcttaat ttacaactgg
    48901 caggcagagg tgagaaaatt cgccccttct ttaagtatcc aagtaatcaa tgggaataaa
    48961 aaagaacgtg aagaattact ggctaaagac acagatatcc gagtgacttc ttatgccagc
    49021 ttaagacagg atctagctaa ttatcagtcg caaaaaattg attatttgat tcttgatgag
    49081 gcacaaatgg tcaaaaatag cagtacgaaa actgcacaag cattgagaga attagctgta
    49141 cctcagcggt ttgcactgag tgggacacca atcgagaata atttagaaga attgtggtca
    49201 ttgtttgcaa cgattatgcc aggatttttc ccgactaaaa caaaattcag ggaacttgcc
    49261 gcagaagaaa ttgcgcaaat gattcgaccg tttattttac ggcgagataa acaaactgtg
    49321 ttgaaagact tgccggaaaa aacagagatg aatctatatt ctgcacttac agaagaacaa
    49381 aaaactgttt atttagctta cttgcgtcaa atgcgtgaag aaatcacatc aatggattct
    49441 gaagcattca agaaaaaccg gatcgggata cttgctggtc tgacaagact gcgacaaatt
    49501 tgctgcgatc ctcgtctgtt tattgaagat taccaaggcg gttccggcaa gctcgaacaa
    49561 gtaaaagatc tactggtagc tgccaaagag aacaaacgaa gagttttgct gttttctcaa
    49621 tttacaggga tgctgactat cttgcaagaa gagttagccg agctagggat ctcgacattt
    49681 tatttaagag gcagtacgaa accacaagat cggttaagta tggtagacgc atttaatgct
    49741 ggcgaaaaag atgtttttct gatttcctta aaggctgggg gaactggatt gaatctcacg
    49801 ggagcagata cggtcatctt gtatgacctt tggtggaatc ctgccattga agaacaagct
    49861 gctggacgtg cacatcggat cggacaaaaa aatgtggtag aagtgtggcg tatgatctct
    49921 gaaggaacga ttgaggaacg catggattca ctccagcaag aaaaacgcga actgttccaa
    49981 aaagtgatcc aaggtaatga agaacagttg acgaaactga ctgaagaaga catccgcatg
    50041 attttaagtg taggagaaat cgaggagtaa gagactcgaa aaagcgttca gtaatgggta
    50101 agaaagcctt tctaaagaag cgattgttta tttgatttaa aaaatagcaa ggaggctggg
    50161 attccatttt atcccagctt ccttgctatc atttttttat ttctattttt aaaggttata
    50221 caaagattgt cttcattgtc tctaacagct gatcaaaaga agaaatctcg atatcgcaaa
    50281 ttggagtctg ttcaattttg cgttctcgat ggttgaacca aagcgcttgc cagttagcac
    50341 tttttgcacc tagaacatca ttgtcgtaat tatcgccaac gtataaggtc tcttctggaa
    50401 gcatatgaaa ttctttctca gctagctgaa aaatctcttt ttctggtttt tggaaacctg
    50461 ttgcttgaga aatgagcata ttgcgggaag gaatccaatt gttcaattga agttgcttca
    50521 gtttttttgt ctgatggtca gtcggcccat ttgtgataat tcctaatggg acattctttt
    50581 ccttcaagaa atcgagggtt tttttgacct cctcatgcaa gcagatatta tcaagttctt
    50641 cctcgtaaat tttttgaaat aagaggccat cttcttccgt aatatgaggg tagtctaaat
    50701 cttttagtga ttggctgatc cgatgtgctc gcatatattc tagtgtccaa tctcctgcca
    50761 ttacttttgg gaagttttca tcactatgat ggcggaaccg gatatatagt ggatgcatat
    50821 ctgcatctga aacaagcgga acgactcttt tgaccgcgtt tcgaaatggc tgctgctgat
    50881 catacatcgt atcatcaaca tcaaacacaa ctgatttaat caaaatttta cacgcctttc
    50941 ggttttcatt gattttttca caaatccttg actattgtaa cagaaaaaat tgtctaaaaa
    51001 agctgataaa taaaggtttt tcttactata tttctatttc cttgacagaa taaggttttt
    51061 atatttcagt ttttttcact aaaaatcgtg aaacacgtca ataagtttga tgaacaaatt
    51121 aatcattatg gtagaagtcg attgatttat tttaatgcaa tctctgtgga attttcgaaa
    51181 gatttatttt tttaatacag tctcaatata actattcaaa cataaaataa cgttatttga
    51241 tttatttgtt tatagtaaat tttatttagt aatcattgct ttaaaatact acgcttatat
    51301 aacagagaaa ataagcgtta taataaagaa cagtattatt taaaatgaca gaaaacatta
    51361 ctattaaaga aataaaaaac ataaaaaatc ttaagaaatc ggtttcattt agcttttgag
    51421 ataaaataat agtacagttt tatacgctgt ttcatatgtt tagaaaattt gaattagatt
    51481 tgaaaactct aatttttaaa tgataaaaaa agcgagaatg ctggttttac tgtatattaa
    51541 ccttagataa ctttcatttt tttaaaaaaa ttatgaaaaa aaggtagcta tttaaaagtt
    51601 gattatgtat aatagaaaca gatgggagat tattatgatc ttctgttaca aaaaagtgat
    51661 tcttatcacg aaaaggagtg gtgcacgttg ttaacattat atacttcccc aagttgtact
    51721 tcctgcagaa aggctcgtgc gtggttgcaa gaacatcaga ttccatttgt tgaacgtaat
    51781 attttttcag aaccattgaa cagttctgaa ttaaaagcga ttttacaaat gacagaagac
    51841 ggaacagaag aaatcatctc gacacgttcc aaagtattcc aaaaactgaa catggattta
    51901 gatgatctgc cgttacaaga attattggaa cttgtgcaaa acaatcctgg attgcttcgc
    51961 cgtccaatca tgattgatga taaacgtctg caagttggtt ttaatgaaga tgaaattcgt
    52021 cggttcctac cgcgcgatgt acgacaatta gaattacgtc aagcacaatt gatggctgga
    52081 ttatagaagg ataatacgaa acttggaaaa ga
//
LOCUS       DAFEEZ010000012        49887 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000012
VERSION     DAFEEZ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.012"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="LP245_000815"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="LP245_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBL1518751.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="LP245_000816"
     CDS             complement(322..891)
                     /locus_tag="LP245_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBL1518752.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="LP245_000817"
     CDS             1077..1979
                     /locus_tag="LP245_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1518753.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="LP245_000818"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="LP245_000818"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBL1518754.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="LP245_000819"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="LP245_000819"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBL1518755.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="LP245_000820"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="LP245_000820"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBL1518756.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="LP245_000821"
     CDS             8547..8732
                     /locus_tag="LP245_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBL1518757.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="LP245_000822"
     CDS             complement(8794..9990)
                     /locus_tag="LP245_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL1518758.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="LP245_000823"
     CDS             complement(10160..11596)
                     /locus_tag="LP245_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBL1518759.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="LP245_000824"
     CDS             11889..12698
                     /locus_tag="LP245_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1518760.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(12884..15037)
                     /locus_tag="LP245_000825"
     CDS             complement(12884..15037)
                     /locus_tag="LP245_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBL1518761.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAAWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(15331..16179)
                     /locus_tag="LP245_000826"
     CDS             complement(15331..16179)
                     /locus_tag="LP245_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1518762.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(16403..18343)
                     /gene="thrS"
                     /locus_tag="LP245_000827"
     CDS             complement(16403..18343)
                     /gene="thrS"
                     /locus_tag="LP245_000827"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBL1518763.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(18680..18859)
                     /locus_tag="LP245_000828"
     CDS             complement(18680..18859)
                     /locus_tag="LP245_000828"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBL1518764.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(18906..20729)
                     /gene="cadA"
                     /locus_tag="LP245_000829"
     CDS             complement(18906..20729)
                     /gene="cadA"
                     /locus_tag="LP245_000829"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBL1518765.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            21007..23286
                     /locus_tag="LP245_000830"
     CDS             21007..23286
                     /locus_tag="LP245_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1518766.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(23379..24026)
                     /locus_tag="LP245_000831"
     CDS             complement(23379..24026)
                     /locus_tag="LP245_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518767.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(24205..24924)
                     /locus_tag="LP245_000832"
     CDS             complement(24205..24924)
                     /locus_tag="LP245_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1518768.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(25055..26206)
                     /locus_tag="LP245_000833"
     CDS             complement(25055..26206)
                     /locus_tag="LP245_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBL1518769.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(26423..27163)
                     /locus_tag="LP245_000834"
     CDS             complement(26423..27163)
                     /locus_tag="LP245_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1518770.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(27167..27490)
                     /gene="rsfS"
                     /locus_tag="LP245_000835"
     CDS             complement(27167..27490)
                     /gene="rsfS"
                     /locus_tag="LP245_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBL1518771.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(27547..28140)
                     /gene="yqeK"
                     /locus_tag="LP245_000836"
     CDS             complement(27547..28140)
                     /gene="yqeK"
                     /locus_tag="LP245_000836"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBL1518772.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(28124..28774)
                     /locus_tag="LP245_000837"
     CDS             complement(28124..28774)
                     /locus_tag="LP245_000837"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBL1518773.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(28784..29095)
                     /gene="yhbY"
                     /locus_tag="LP245_000838"
     CDS             complement(28784..29095)
                     /gene="yhbY"
                     /locus_tag="LP245_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBL1518774.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(29111..30220)
                     /gene="yqeH"
                     /locus_tag="LP245_000839"
     CDS             complement(29111..30220)
                     /gene="yqeH"
                     /locus_tag="LP245_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBL1518775.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(30217..30744)
                     /locus_tag="LP245_000840"
     CDS             complement(30217..30744)
                     /locus_tag="LP245_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBL1518776.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(30924..31709)
                     /locus_tag="LP245_000841"
     CDS             complement(30924..31709)
                     /locus_tag="LP245_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBL1518777.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(31702..32571)
                     /locus_tag="LP245_000842"
     CDS             complement(31702..32571)
                     /locus_tag="LP245_000842"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBL1518778.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(32572..33951)
                     /locus_tag="LP245_000843"
     CDS             complement(32572..33951)
                     /locus_tag="LP245_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBL1518779.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(33959..34378)
                     /gene="fabZ"
                     /locus_tag="LP245_000844"
     CDS             complement(33959..34378)
                     /gene="fabZ"
                     /locus_tag="LP245_000844"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBL1518780.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKTSAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(34403..34879)
                     /gene="accB"
                     /locus_tag="LP245_000845"
     CDS             complement(34403..34879)
                     /gene="accB"
                     /locus_tag="LP245_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBL1518781.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(34882..36117)
                     /gene="fabF"
                     /locus_tag="LP245_000846"
     CDS             complement(34882..36117)
                     /gene="fabF"
                     /locus_tag="LP245_000846"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBL1518782.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(36136..36873)
                     /gene="fabG"
                     /locus_tag="LP245_000847"
     CDS             complement(36136..36873)
                     /gene="fabG"
                     /locus_tag="LP245_000847"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBL1518783.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(36885..37802)
                     /gene="fabD"
                     /locus_tag="LP245_000848"
     CDS             complement(36885..37802)
                     /gene="fabD"
                     /locus_tag="LP245_000848"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBL1518784.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(37909..38133)
                     /locus_tag="LP245_000849"
     CDS             complement(37909..38133)
                     /locus_tag="LP245_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBL1518785.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(38186..39148)
                     /locus_tag="LP245_000850"
     CDS             complement(38186..39148)
                     /locus_tag="LP245_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBL1518786.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(39158..39598)
                     /locus_tag="LP245_000851"
     CDS             complement(39158..39598)
                     /locus_tag="LP245_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1518787.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            39904..40869
                     /locus_tag="LP245_000852"
     CDS             39904..40869
                     /locus_tag="LP245_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBL1518788.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(40926..41156)
                     /locus_tag="LP245_000853"
     CDS             complement(40926..41156)
                     /locus_tag="LP245_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBL1518789.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(41242..42129)
                     /locus_tag="LP245_000854"
     CDS             complement(41242..42129)
                     /locus_tag="LP245_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBL1518790.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(42218..43441)
                     /locus_tag="LP245_000855"
     CDS             complement(42218..43441)
                     /locus_tag="LP245_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL1518791.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(43458..44504)
                     /locus_tag="LP245_000856"
     CDS             complement(43458..44504)
                     /locus_tag="LP245_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL1518792.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(44668..46395)
                     /gene="ptsP"
                     /locus_tag="LP245_000857"
     CDS             complement(44668..46395)
                     /gene="ptsP"
                     /locus_tag="LP245_000857"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBL1518793.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(46395..46661)
                     /locus_tag="LP245_000858"
     CDS             complement(46395..46661)
                     /locus_tag="LP245_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBL1518794.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            47140..49374
                     /locus_tag="LP245_000859"
     CDS             47140..49374
                     /locus_tag="LP245_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1518795.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            49522..49842
                     /locus_tag="LP245_000860"
     CDS             49522..49842
                     /locus_tag="LP245_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBL1518796.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
BASE COUNT        14254 a        10708 c         8730 g        16195 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctaaattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt gacaattttt gtcacaacct tttttgccga gtaaacggtg ttcaaaagcc
    12781 agtttctcgg tatgaagtca aatttaagca aaaatgtgag aagctatttt cacaaaattt
    12841 ttcttcatac tcgaaactaa gcggcttttt cacgacctct tttttatttt gccatgaaca
    12901 tatcataata cgcgtccatt atttctttag caatcgtcaa gtttatgtgg tcttgttcgt
    12961 ctaataagtt cggcaagaca acactgatgg caatttccgg attgtctgtt ggtccgtatg
    13021 ccacgatatt actattgact gtcgcaatat ctggatgacc ttccgcaacc gtttctgcag
    13081 tccctgtttt tgcggaaagg tccattttcg cactggctaa tggtttggct gttgtgtaag
    13141 gatcggtacc atggacaact tggtggaatc cttcacggag gatcgccata ttttctgcag
    13201 aaatattgac cgtattttct actgttgtgc caatttcttt cttcacttca cccaagtttc
    13261 cattttcgtc attgccatag atcgctttga ctaggtgcgg ctgtactcgt ttcccgccat
    13321 tagcgactgt tgaagcatat tgagctaatt ggattggtgt atatgtgtca aactgtccaa
    13381 atgccaaatc ggtaaagtta cctggagcat accattcttt gccattatcc gcattgaact
    13441 tcttcatata atcaacagaa cgtgagatcc caggagattc attcggcaaa tcgatcccag
    13501 tcgttgtacc aagaccaaac tctttgaaag agtctctcaa ttgctgataa gctttagctt
    13561 cttcatctaa actaggtagt cccattccag gtgtatagtc tagtcctaac atctttaacg
    13621 ccactttgat catatacgta ttagaagaca attccgatgc tttgactgca tcaagagcaa
    13681 cttgtccgct tcgattaaag acagagcttt tttctgaagc accttgcaga cgaatcggct
    13741 catcaatcaa aacttgattt ccgctgatcg cgttacttgc ccaggctgct gtcaaagtac
    13801 cagccttgac tacagaccct ggatcaaagg cgctagtaat cgtgcctaaa gcattctcgg
    13861 tgatttcttt ggaaccttgt tcatgactga aaccagtcat tgctagcact tctcctgtct
    13921 gaggattcat agccactgca taagcaccag gcgaatactg tgctttgccg ttgttgatca
    13981 atgtttgata attccttttc aaaatttctt ctacttttga ttggaattct gcattcatag
    14041 ataacattaa attagaacct ttttccccag agaagatttc tttttgattc gaaacatttc
    14101 cttcattatc aagggaaact tcatattggg ttttggttcc ttgcaggaca tcttcatatt
    14161 gtttttccaa ataactttgt cctacacggt cattccgaga ataacctttt gctaggtatt
    14221 tctctgcttc atctgctgga agtccttgct tttcagtcgt cacactgcca agaatacttt
    14281 tcagtgaact tgctgcatta tattctcgtg tccagtctgt gccagtcgaa actcctggaa
    14341 gttcagaagc gcgttctgcc acaacagcta actcttgatc agtaacacca gagtttttga
    14401 tatagacagt gtttaattca tatgcactat tcatccgttt aaagatggta gcaattttta
    14461 attgctcctc gtttaaatta atctcatcag ctgtgacttt attgaccatc gcactatatt
    14521 gttcgctgtt ccctaattgc ttttcttttg ccgaaagtct ttttgtggct tctttcaaat
    14581 gtttgggatc agccagccaa aaatcttttt tatctctatc tgtcagattt tcatctaccg
    14641 gaacatcgat cagcgagttc agcttcgttg cgatttcaag caaatcttta gccgtaactt
    14701 gtgttcctct cgtatatgtg atggcctgat tcgctttatt cgtaactaaa gcttttcctg
    14761 tggagtcgta gatcattccg cgaggagtac tttcttggac cgtaatcgta gaagtagact
    14821 tcactcgcgc ctccatctct tcgccgttca cgatctgcaa ataacccaat ctagcaatca
    14881 acgcaacaaa taacgtaaat ataatgaaaa aaagaaaatt taagcgaaaa ggaacatggg
    14941 accggcgaaa cgttttgttc ttaggttctt gtgcaccttt tcttattttt tctaaccaag
    15001 aagtatttaa tatttttttc ataaaatctt tcatcatttc ctatccttcc gcctatttac
    15061 attcatgctt cattgtaccc aaaaacttct taataaaaaa gaaaaaatgg gcggagcaag
    15121 aaattcttta cctaatttca agataaaatc aactttttgt ttcacagcaa tcacttaaag
    15181 ttacatatcc aactattttt ttcattaaaa aataaactta tttttgaaaa ttatgttttc
    15241 ttaagtcgtg aaacactttg atggatcatt tatttgtgga aaactacgtt ttgttattct
    15301 aaaaaactta tataaaaaat agtaaggttt ttatttcgaa tccataaaat attcttggat
    15361 tgcttctcgt gtttttttca ctttttcgct aagcttttcg tttttagcca tatagaaata
    15421 aaaaatgata tcgatcgtag caaattgggc caaaagtgaa ttagttgccg cacttcgatt
    15481 cgtgatttct tttggtctag atgtttgtac gagtacatcg gctatcttgc taagcgggtt
    15541 atttccaaat tgcgtcaacg caatgatttc gatattcatg cttttcgcca gctcggctaa
    15601 tgcgactaca tctgcacttc tacctgagtt tgaaacaagc caaagcactt tctttttctc
    15661 attgctgaca agttgcggga gcaagacgtg gatatctttt tcaaaaatga ttggcttacc
    15721 gacacgagac catttttgca gaatatcttc tactactaaa gaagaggcgc caaccccata
    15781 taaaaaaaca gtctctgccg attccaaaca ctctacgact ttttggatcg tttcttcttc
    15841 tagaatatct actgtttctt ttatcgctac ttgtgcattg ttaccaagtt tgtttttgat
    15901 agagtaaaag gactcatttg cttctatatc actaaaacct tcatcgattc cagtctgtag
    15961 ttctgttgaa atcgtgattt tgaagtccgt cagactttga aaaccgattt ttttggaaaa
    16021 acgtacaact gtcggcgcac tcaacccgga agcttctgct aattcattag ctgtcattgt
    16081 agggaccttc tcaatattac cgataatgta gttggccaac tttttttctg ctgaagaata
    16141 atcttccatc atactttcaa tacgactaat tacgctcata agttcctcca cccttttaat
    16201 gatagtctat gtaagtatac catatcagac ccttattcac ggtcgtatac tggataaaaa
    16261 acaaaaaaac aatccgccca acagaatatc ttatcccatc aatcccacag attctattga
    16321 gcatctgtgt ctttgaggaa tacctgttat ctattgttcg gattgctttc tatctactac
    16381 ttttttacag gaaatttacc tattagtttt ctctgctgta atttttgact tctgcttcca
    16441 tagcatcaat aaagatattc aaatcttcta cagctgtttc tttacttcca taacgacgta
    16501 cgttcactgt tgcatcttcc aattccttgt ctccaacaac taattggtaa gggatctttt
    16561 gtgtttgaga ggcacgtatc ttatagccca ttttttcatt acgatcatca acttctacac
    16621 gcaacccctt catttgcaaa cgttctttga tttcataagc ataatcgcca tgtgcatcaa
    16681 cagaaacagg gatgattgtt gcttgtatag gtgccaacca tgttggaaaa gcgcctttgt
    16741 atacttctgt taaataagcg acaaaacgtt ccattgtaga aacaattccg cggtggataa
    16801 ctactggacg atgcgtattt tccccgtctt ctccaacata tgtcaaatca aagcgctctg
    16861 gcaataagaa gtctaattgt atagttgata atgtttcttc tgtaccaaga gctgttttga
    16921 cttgaacatc tagttttggt ccgtaaaagg ctgcctcgcc ttctgcttca aagtaatcta
    16981 gttctaattc atccatagcg gctttcagca ttgcttgggc tttttcccac attgcgtcat
    17041 catcaaaata tttatctgta ttgtttggat cgcgatagct caagcggaaa cgataatctg
    17101 taatattgaa gtcagcatat actgccacca tcaattcaag cgtacgttta aattcatctt
    17161 tgatttgatc aggacgaaca aatgtatgac catcattcaa cgtcatttct cgtacacgtt
    17221 gtaaacctga caaagcacct gatttttcat agcgatgcat cattcctaat tcagcgatac
    17281 gaattggtaa ttcacgataa gaatggatcg tgtttttgta gaccatcatg tgatgagggc
    17341 agttcattgg gcgaagaaca agcatttcgc catctcccat atccattggc gggaacatgt
    17401 cttcttgata atgatcccag tgtccagatg ttttgtacaa ctcaacatct cccattattg
    17461 gtgtatatac atgttggtaa cctagactaa cttctttgtc tacgatataa cgttcgatcg
    17521 tgcgtcggat tgttgcccct tttggaagcc agaatggcaa accagaacct acttctgggg
    17581 aaaccatgaa caagtcaagt tcttttccta gtttacgatg gtctctttct tttgcttctt
    17641 cacggagacg gatatattct ttcaaagctt tcttgtcaaa aaaggctgtc ccgtatacac
    17701 gttgcatcat ttgattgttt gagtttccac gccaataagc acctgccact gataataatt
    17761 taaatacttg tatacggcca gtggatggaa catgtggtcc acgacacaaa tcgatgaatt
    17821 cgccttgttg ataagcagta atcacttctt cttctggcaa ttcactaatc agttctactt
    17881 tgtacggatc acttgcaaaa atttctaatg cttcctgttt tgaaagaaca cggcgttcga
    17941 tcggcagatt ttctttgacg attttcatca tttctgcttc gattgccggc aaatcttctg
    18001 cagttacttg gttttgtcca ttatctgtat cgtagtaaaa ccctgaatcg atagctggtc
    18061 caacgccaaa gtggatattt ggatagaggc gacgcatggc ttgggccatc aaatgagctg
    18121 ctgaatgacg gactaagcca agtgcatctt catggtctgg tgtgatgatc tcaatacttg
    18181 catcttcctc gattggacga gtcaaatcaa cgagttttcc gttcacttta ccagctaaag
    18241 ctttttttgc taagcttttt gaaatgcttt cagcaattgc caatgttgtt gttccagact
    18301 caaattcttt gactgcacca tctggaaaag taatttttat cataatagtt tcctccttga
    18361 aatgttttga ttgatcagat catcaagctg aaaaacaaaa aaatcctagc atctcttgaa
    18421 aagagatact aggacgaaaa gttcgtggtt ccacctaatg ttcaaacgca aatgcgttcc
    18481 tcaagcgttg taacggtccg accgcccttg cttcaacaag ggtttcgaaa gtggtcatcc
    18541 tttggttttc tcctggaaaa gtttcagcct agcttttcct ctcttatcga agactctcaa
    18601 attcagttgg ctttctcatc aatcaattat gtgtttattt aaccactaat aaatagaaaa
    18661 atcaagtggg aaactaaact tattttttcc attccccatt tacaccgtat gttccttttt
    18721 tcatctcatt gatgatgaca tggatgtgtt cttttggtgc ctgcgtgttt ttatgaacag
    18781 cttccgtgat atctttcatc atattttcta attgttccgg actgcgacct tctactaatt
    18841 cgacatgtac gaatggcata atgctctctc ctctttctga tcgttctttt ttcaactcga
    18901 ttctatcata ctatgtttgt cttgggtact gaatcaggaa aaatggctgg atcttttttt
    18961 gctctcaagg cactcaaaat agagaccgta tccacgactt cttgcaaaac agctccgaat
    19021 aatgcgggga ttagtcccgt acttgcaatt aacatcaaaa aaatacaaat aaagatgcca
    19081 atcagtacag actgtttcgc tattctcatc gtatctcttg aaatcactac tgcttttgct
    19141 acacgcaaga gatcatcttt caagatgacc gcatctgcac tttcactagc agctgtagaa
    19201 ccatgagccc ccattgcaat accgatatct gcagcagcaa gtgctggtgc gtcattcacg
    19261 ccgtctccta ccatcgcaac aggtctttga tctttaggga tactttctaa aatggtcagt
    19321 ttatcttgag gcaagctacg ggcatgtaca gaatctaatt ggactttttc tgcaatcgtt
    19381 tgagcaatgg cagatccatc cccggtgatc atcatcaaat ttttcacatc aagttttctt
    19441 agctccttga ttgtctttgc tgcttctggg cgaatctgat ccgaaaatag gatcgttcct
    19501 gcaaaagatc gatcaattgt tacatagatt gctgtattgg acgtttctat ttcttcagct
    19561 gaaacaaaag aggcacgtcc aatctttact tcatgattat tgactactgc ttggattcct
    19621 tgaccggtca cttctttcag ttgactaaca ggatacagtt ggctgttttt cacgttgttc
    19681 actaacgaac gagctaagat atggctagat tcctgttctg cactagctgc atacagaagt
    19741 agctcttctt tttttattcc attgactggc tgaatcgcct ctacttccaa tatccctttg
    19801 gtaagcgttc ctgttttatc aaaagcaatc gtttttgtac gtgcgagctt ttcaatcgtt
    19861 gttccagttt ttacaacgat cccgttttta cttgaacggc tcattcctgc aactaaagca
    19921 atgggcgcag ctagaatcag tggacaaggt gatgccacta ccagtacctc agcaaatcgt
    19981 aaagggtctt ttgagaacca ccaagaaata ccaccgatca aataagcaat caacgtgaaa
    20041 gggactgcat aacgatcagc taaacggaca aatcgggcag gcttttcttt tgattcttcg
    20101 actagtttaa taatcatttg atactggctg tctgcggcac gtttttcagc gatcatttgg
    20161 atcgatccgt ctccatttaa agaccctgac ataatctgat ctccaggttt cttggtttcc
    20221 gggcgggact cacctgtcaa agaagattca tcgaccgaag attctccttt ggtcactcga
    20281 ccatctgcgg gtacaagttc gccaggcttg actagtaact ggtcatcaat atttatttca
    20341 tcgattacta tatcctgcaa ttttccttct ttgaatcgat gggcaattct tggggtgtta
    20401 tctaacaaag actgcagttc tttacccgct cgtttattcg cgtaatcctc tagactatct
    20461 ccgcccgtaa gcatgatcaa tatcatcaaa ctagcccagt attctttgac ggctaatgtt
    20521 gcaaggattg cggtaatcgc taatacatct acgccatatc ttcctgaacg taacgtcttg
    20581 atcatttcca aaaacatcaa gaaggcgaga atccctccag taaatgcgac aatcgcaaat
    20641 gcaagggccg gctggtgaaa aacaaattca cttaataaag ctatcccacc aataagcaaa
    20701 gtaagtaaaa attttttgaa atgtgtcatt gttttttctc ctcttttatg tgacttagag
    20761 aggttagtaa taaatttcca gctgcctctt tcatcttaag catagtcctt gactagcact
    20821 ttttaaaaca ataggcctta attgaaaaca actatcacta tcagcgtttc caaaattcat
    20881 cagttctaca aacaaaaata ttcagcaagg attacttttt cgattcatca gttaaaaagt
    20941 accttttttc gaaaaactat gctatacttt taattcgtta tttacggcgg aaggagcaaa
    21001 catgcgatga atgagaaaca actagaacaa acgcacgtgg atgaaacgat cgaactaatc
    21061 cagatcgaac aaaatatgct ggatacaaaa caacaagaat tgactcagga aatgaatcat
    21121 tcgacaaaag acacagctaa tcacaagatt cgagctggtt ccaatgaagc tttttatgaa
    21181 tctgctgttg aatatcgcca acatgagcag gaattgcttt tgaaatacca tactcttgaa
    21241 gcacagcaaa aacgcctgca aacgttgtct gtcatgaaag atagtcctta ttttgcccgt
    21301 atcgacttta aagaagaccg tgaaacagaa acattatatc taggtatcgc ttctttaaga
    21361 gatctggcag aagaaacaat cgttattgac tggcgcgcac caattgccaa tctttattat
    21421 gaaggtgaga ttggtcccgc attttatgaa actgaaacag atagaataga tgtcgatctg
    21481 cagttgaaac gacaatttaa aatccaagaa ggacgtattt tatctatggt agatacgtcg
    21541 gaagtaatca atgatgactt tttgctagag atattggatg aatcatcaag caaccatatg
    21601 aaaaacatcg tctctacgat acaaaaagca caaaatgcaa tcattcggga cacaacaagt
    21661 aaagtaatgc tgattgaagg aatcgccgga agtggaaaga catccgcttt gcttcaacgt
    21721 attgcttttc tgttgtatca taatcgcaag tggctcgagg ctgaaaacgt tcttctattt
    21781 tcacccaacc atttgttttc tgattacatc tcgactgtat tgccttcatt aggtgaaagc
    21841 ggcgtgccta cacagacatt caaaaattat ttggtgcagc tgctgccaga gttttcttta
    21901 ctagatgaac agcaacaaga aagtggtttt ttgctagggg aaaaagatcc gatacaagtg
    21961 atgaaaagcg gattgacctt agtcgatcag attgatcgct atatccaagg catcacaaac
    22021 tacggtccct tgttccgtga tatgaaaata aatggccgta cgatcctatc aaaggaatcg
    22081 attcgccaat ggtataaaga aacaaatgaa caattacctt tacatcatag actttctcta
    22141 ttacaaacga agctcctgaa aaaattaggc ggtctgcaaa aagacgaaac acgtcagcaa
    22201 tgggtcaaag atctggcgga agaacagctc caagaactat acgcaacaga tccaaatctt
    22261 gaatatacag aacaaaagga gcgttcatta cgtaaaaaac tggccaacca aatcgtacgt
    22321 aaaagattcc gtcgaatcca tcgagggatc atgaattatc aatttgtcaa tataacgaaa
    22381 caatatctcc actttctaca aactgtgcca ctttctcttc taacacgaca taaaatcagc
    22441 gagaccaggt ggcaggaaca tttgacaact gttcgtacac acttgcgtca aagagaattg
    22501 cgtcaagagg atgctgtact attcttttta ctgatgcgcc gaacatatcc agtgacggtt
    22561 acacacaaag ctcgctatat ctttattgat gaaatgcagg atttcgcacc atcacaagtg
    22621 gcattgctgc aagccttgtt cccaaaagca aatttgactt tctgtggaga tctaaatcaa
    22681 aatgtctttg gaaatgaaac gatcgttgga tcattggaag accttttcgt ggaccgtgaa
    22741 gtcactcgtt tccaattaac gacaagctat cgctccacaa aagaaatcac tgattttgct
    22801 aatcatttta ttgtgaaaga acatcaagta gaaacaacag caagaaaagg agaccttcct
    22861 ttgctcatcc aaggaacaac agatgatatc aaattgaatt ggttagcaga taccattcga
    22921 acgactcagg gaaaagcccg gtattggcgt acagcaatca tagctaaaac acaagaagaa
    22981 tgcgaagctc tttatgctca actgccagac gagttgaaac aacaagtcca gctgatttta
    23041 aatgagagtg actttatgaa gcgttccatt attttacttc cagccttttt agcaaaaggt
    23101 ctggagtttg accgagtttt cttgtgggat gtagatgcag aacatttttc ttctcagcaa
    23161 gacaaattga tcctttacac catgtgtaca cgtgcgatgc atgaattgac cctttttacc
    23221 tccaataatg aaagtccttt gttaaacaat atggatattt catcttatga gaaaaaagta
    23281 ctgtaagtaa aaagacaact gctatcatta atgttagcag ttgtcttttt atttacaata
    23341 ataattgcag aaaaagtaat tcaatcattt aaggtcattt attctatata taaatccaaa
    23401 tctgtttcag gatattttaa tttgacaagc gaaataatca ttttcagttc ttccatgttt
    23461 tctggatatt ctgggtcaaa taccttgcta tgacggccaa tcccgccatt gtcgatcaat
    23521 cggtaaattc gattccattc aatgaattgg tcaattgatt ggaaattgct gattggatag
    23581 ccgccacaat ccaaaatctc tgatacacga aatgctaggt atgcactatc gatcacttta
    23641 ttttttttcg tgtctatctt ctcatttctt tcgataagaa ttttttcagg acgatgtttc
    23701 aagctccact ctaatagtag aaagaaagcc tccatccgat actcttcttc aaataaccga
    23761 aaggctgaat cagaacgacg aaaaagcagc ggaatcagat aattttgtct ataaatcagc
    23821 attggtgcgc ggtccaccat acactctaaa taacggttca gataccctgt accgacatag
    23881 tttcctaatc gatagccttc aacgccgaat cttgcgtatt tttgcgctaa ttttgaacaa
    23941 tcagttacgt tcacagctaa ctcttctact ttgcggtaac cgcttaagat acgttcaaaa
    24001 ggttctaaag tgatttttgc ttccatattc ttccccgtcc atcttccaca tacttcatat
    24061 catttcacat gatacttatg ctctcatcat accacaggtt gaattagaaa agaaaataaa
    24121 tcacacaaaa aagcaagaca atctgttagt gagattgtct tgcttttcga aaaagactga
    24181 atacttttcg ttaaaactgg ttgcttagtc ttctaatgcc acattatgga acacatgctg
    24241 tacatcttct agatcttcca gtgcatcaat cattttttca aatgtttctt gatcttctgg
    24301 agatagtgtt acctcgtttt gagggatcat ttggatctca gcgattgaaa aatcagtgat
    24361 tcctttttct tttaatgctt cttgtatact atggaaatcc gctacttcac cgtaaacgat
    24421 gatttgtcct tcttcttcca ttacatcgcg aacatcgatg tctttttcca ttaggtattc
    24481 aaggatctcg tcagcgtctt ctcctgcaaa agcaaagatt gctgtattgt caaacatgta
    24541 agaaaccgct ccggaaacac ccatgttccc gccatttttc ccaaatgctg cccgtacgtc
    24601 tgctgctgtt cgattcacat tgttcgtcaa tgtatcaaca atcaccattg agccgcttgg
    24661 tccaaatcct tcatagcgca attcagagta tgtttcatct cctgcacctt ttgctttttc
    24721 gattgctcgg tcaataatat gttttggtac attataagtt ttagcgcgat caatgacgaa
    24781 acgtagtttt tggtttgcat gcggatcagg atcacctgat tttgctgccg cgtagatttc
    24841 aatcccaaat tttgcataaa tccggctatt attagcatct ttagcagttt tctttgctac
    24901 gatatttgcc catttacgtc ccatattttc acttcgcttt ctgatttgat agtttcataa
    24961 cgcaaaaacg tcctgttcca ttatacttgt gaatcacgat tctgtgaagc tttttttctt
    25021 tcttccttca ttcttctcat ttttagtcaa ttatctatac tcggattggg atttgcccga
    25081 aattctgttc cggaatattg cctcccaatt gatagatttg atcacttcta actaacagtt
    25141 ccgcttcttg tgcctctttt tttccgattc gggaataaat agaaatctct tttttttctt
    25201 ttaagaatct tcttccagca tcggtaaatc caagtagtcg aagataattt ttattttgtt
    25261 ggacaggaat ctcttgcttt ttgatattca gcaagacata acaagataat cgttggatcc
    25321 gtgtccatgt atatcttttt gtttttacct ttgacacaaa atcctcaaaa ctatcagcag
    25381 ttgcagctgc tgttttcatg cgcgattcta ttccttcggt catctgatag atatctgtca
    25441 gttccagcaa agtagaagat aacaaccgat aacgcaaata cggccaataa gattcccaag
    25501 tctgcagcga acaagttgaa agatcttctt ctgtctgagg cggcacaagt ccagctattc
    25561 tttttccttc ttctaacgca tggcgaatgg ctgttgcact ggctatcctc tgatctgtga
    25621 tgattttttc atgatagcct gcacttttac gtcggatcgg atgtaattcc atagggtgga
    25681 catacttggc attttccttt gcataactta atcccaagat atgatttggc gaagaaaaat
    25741 caagcgtaat atcgggatac agactgcgaa aaacctcagt cattttttgc ggataactat
    25801 acgtttgatc agacagttct tgaaatgcct cttctatcct atcttgattc tcttggacaa
    25861 agcgtccgaa actgctgtaa tcaaacgaag tctcttcttc tgttccaaaa cacaaactgt
    25921 cacagtccag tgtttgcaag atttttactg cacctttagc aaaatagtca gctgactgaa
    25981 ccgcccattc gacgggaagc tccactacta aatccacacc attttgtaaa gcttcattcg
    26041 cgcgatgcca tttatcgatg atagccggtt cgcctctttg caaaaaattc ccgctcatta
    26101 cagcaatgac gacctctgct cctgttattt ttcgtgccat ttccacatga tagcgatgtc
    26161 cattgtgaaa aggattgtac tctacgataa tcccgcagct tttcatgcgc atcctccttc
    26221 atagttatcg ataaaaaaga aatagagaca agtaaaaaaa ggcaaaaatc ggaaaaaata
    26281 cccgaactat ataaactatt ctcgcaaaca caatacttct gcgacgaaaa gctgcactgc
    26341 aagagcaatg cctatatcgt tcggatatat aatttatgtt gaagatttat tcttttcttg
    26401 ttaactcgag caggcaaaac cgctagtctt tgtatgctac aaagaaccag cgctttgatt
    26461 tctctgatgc tgcttcgtct gtaaaatcag aaaatgcttc gactttcgaa aagccgctgt
    26521 tttccagcat tcttaaataa ctttccaatg gataggtacg ctcttgatgt agttcatctt
    26581 cacgaataaa tcgaccagac ccttcttgtt cttcaacgaa aaaggtaaga aaatgttcga
    26641 tgctgtgttt ctcgcttcct ggataactat cccacaaaaa agcaaaatta tccccttgat
    26701 aatgatagct atattctgga aaaacctcat ctacttgata ggtggagtgt acgtcaaata
    26761 aaaatcggcc attttcttct aacgcttgat agacttcatc aaacacttgc tgtacctctt
    26821 gtctattttt catatagcac agcgaatcag aaaaacaggt aattgcctga tattgtccga
    26881 tttctgataa atcgagcata ttgccttcca caaattggat cgatgcgtct tcttcatatg
    26941 ctcgctggct ggcaatcatc aacatctctt ctgaaaggtc taaccctgtc actttatatc
    27001 catcttttgc aaaggcaacc gctaatgctc cagtaccgca tgccagttcc aaaatatttt
    27061 ttgtgtcttc ttgtaaatga cgtttcgaaa aagctaacca ttgctgataa agtgtttcgt
    27121 ccatcacttc atcgtaaatg aaagcaaatg tttcataagc catatgttaa tccaaccatt
    27181 cactaagatc gactagcgga gcatctgacc atagtttttc cagattatag aaatttcgtt
    27241 ctggcgcatg gaaaacatgt acgatcacat ctccaagatc gatcaatacc cattttccgc
    27301 cttcttttcc ttcaatacgt tttacttcat atttgttttc ttcttcttta tcaatgattt
    27361 cttctgtaat tgcgttgatt tgacgttcgc tatttgctga acagatcatg aaataatctg
    27421 ccaacaagga aacatttcga acgtctaaag cgataatgtc ttctgcccgt tttgaatctg
    27481 ctgcttcaat cgcaattttt aattgttctt tactatctat gatgatttcc tcctaatatg
    27541 agcagcttat ttttttgcta cccagtaatt atatgtttcg attgtttttg gataaatctg
    27601 ttgttcttgc gcaagcaaat gggccaatgt atgttttgtt tcaaatgcta cagcttcgtc
    27661 tagatcagcc catgcaatgg ctcgtgcatc ttgtacccca ggaaaatctc gacctggttc
    27721 aatatagtct gctacataaa tgattttgtc aaggagactc atcttagcag ccccagtcgt
    27781 atgcacccgg attgcatgaa gaatctctgc atcggtgatt cctaattccc gctctacaaa
    27841 cgaagcgcca acaagaccat gccagattgc attattataa ttcaataact ccggatcaaa
    27901 accgtctctt acgattacca ttttgaactc ctcatctggt cgttcttttg cataatcatg
    27961 tgtcaatgca gcaatactag ctttttcagg agaagcaccg tattttttgg caagagccac
    28021 ggctgtttct tctactccaa gcacatgctt gaagcgttgt tcgctcattc tcatctgtat
    28081 tttttgcatc aggttttctc tagaataagc agtatattca ttactatagt ccatattcat
    28141 acaacccttc attttgaata taatcaatta ctttatctgg aacaaggtag cggatagaac
    28201 agccttcttt gatcttttga cgtattttcg tggaactgat gtcgatctca ggtacatcta
    28261 cccaaattac aggatatgga gtatccgttg tgtatcctgg tcgacgtata cccacaaagt
    28321 tgaccataga agtcagctca tcgattttat accattttgg caaatattct accatatccc
    28381 caccgataat aaagtaataa tctgtatccg gattgttttg cgtcaattcc ttcatagtat
    28441 cataggtgta acttttccca ccacgagcta attcaatcgt ttcaatctgc aaaaaaggat
    28501 tgtcttccac cgctaattcc aacatgttga gtcgatgttt tgcatcaatc gtctgtttct
    28561 catcaacatg aggtggctga taagaaggca tcaaaaatac gcggtcaaga cctaaattcc
    28621 ggccagcttg ttcagccatc actaaatgtg caaggtgaac gggattgaat gttccgccca
    28681 agatccctac ttgctttttc ttctctaaga attgaggcat ttcttcagga aataattgtg
    28741 aacgaacaaa tgtcttagct tgcgtattca tcatggtcac tccttatatt gcttttactt
    28801 cttttgatag cctttgatac ttttcttttg tggaaggttt gtataataca ataacacgtc
    28861 caatgatttg gacgatttcg caatctattt ctttttctaa tacttgagct gcttcttctg
    28921 caatctcatc tgtattttga agtaacgata ctttgatcag ttctcttttt tctaaagctt
    28981 cttcaatttg aacgatcatt gctgaattga tcccaccttt tccgatttga aaaatcggct
    29041 gaagatgatg cgctttgcta cgtaaaaaac gcttttgttt tcctcttaaa ctcataattt
    29101 tccttcttcc ttaaatcaat gctttgcgtt tcaatacatc tacacccttt ggcgcccagc
    29161 ccgcaattac tactggcgct gttacagtga tccagcctag accggcaaaa acgatgtctg
    29221 ttttttcttt cacagaaaac tcaaaacgaa caagctccgg aaatgcctcg acttcatcag
    29281 gacgaggagg ctgtaataat ccacctacat gtttttgata aaattcgtct gctttttcca
    29341 gtttcgttcg atgaatattt acatcatttg acacataagc aataaatgaa gcacgattgc
    29401 cgctgataaa atcaaatctt gcaagtccgc ccaagaaaag tgtttgccct tcattcagct
    29461 gataaacttt aggtttgatt tcttttaacg gtgcaatgat ccgcaaatct tttttaccta
    29521 agtagtgcgc catttgatgg cgatggataa ttcccggtgt atcaatcaaa aaatgcccgt
    29581 catctaaagg aatctcgatt ttatccaagg tcgttcctgg aaactgcgaa gttgtgatta
    29641 catcttgtac tcccgctgta tttttgatga tttgattgat aagcgtcgat tttccgacat
    29701 ttgttactcc gacgatatag acatcccgtc catcgcggta ttcttcgatt ttttctaata
    29761 gttccgtcat ctcatgagat ttcttagcac tagttaataa tacatctact ggacgaattc
    29821 ctgcttcgta agcacgttcc ttcatccatt gtgttaattt agtttttttc aatgatttag
    29881 gtaatatatc cactttgttc ccaactaaaa gtactggatt gtcaccgaca aaacggtgta
    29941 gtcctgggat tagtgaacca ttgaagtcaa aaatatccac cacattgacg atcaatgcat
    30001 ctttttgccc taattcattc agtaagcgca aaaagtcgtc atccgtcaat gagacatctt
    30061 gggtctcatt ataatggcgt aatctgaaac aacgctgaca atagacttcc ccggaagcta
    30121 aacctttttc caaagccgtt tgcggcgtgt atcctaattc accgggtttg tttgtttgta
    30181 taacggcacc acagccgata cattgtaatt cttctgtcat tcgattccac ctcgccagcc
    30241 catatcaggg tgttttgcta atagataggc cataattctt ttttcccaaa aacgattaaa
    30301 ttgtgtcttc caactatctg ttgcgataat gggttttaca aggatgctac gtatccctgc
    30361 acgattggct ccacgtatat cagtcataat ctgatcgcct accattacta tctcatcatc
    30421 tgctaaatcc aattgtttct ttgctatgtt gatccctctt gctaaaggtt tcattgctcg
    30481 tgcaacatac aaaagatcaa atttttcaat cgctcgcgcg acacgttttg aattattgtt
    30541 tgaaacaaca acaacaggga ttcctgcatt tttcatttct aaaatccaag taagcaactc
    30601 ttctgttcca tctggattat tccatgcaat caacgtattg tctaaatcgg tcaatactgc
    30661 tttgatgcct agattcttta attgggcagg tgtaatctga tagatggctt ctaccatcca
    30721 tgttggtttg taatttgaaa acatgctgtc tcctcatctg caaaaaatga aggagcacat
    30781 aaagtactcc tcaaccccgt attatactgc atatcagcaa aaaaaactac ctctatactc
    30841 gttcgtcttt cagaaaaagc atttctttac aaaatgacca aaaataaaga ttgatcacag
    30901 aaaaatttag aaacaaaaaa caactaatat tggcggaacc tcttgtatcg tttttccagt
    30961 aatttatgct gatctaatcg aacaagttcc gtcaatcttt caatcaacgc ttttttcata
    31021 atgtgtgcga ctttatatcg tggcaactgc tcgccgttga acgtttcagg aataactcga
    31081 tcaacgattc ctaactcgcg tagttctggc gcagtaattt tcatcaactc agctgcttct
    31141 gcggcgcgac taccgtcttt ccacaaaatc gacgcaaatc cttctggaga aagcacagca
    31201 taaatcgttt cttccagcat ccagacttca tccgctaaac ctagagcaag ggcaccgcca
    31261 cttccacctt caccaatgat gatggcgatg atcggtacct ttaaatcaga catttcgagc
    31321 agatttctgg caatagcctc tccttcgccg cgctcttctg ctcctacacc gcaatatgca
    31381 cctgctgtat tgatcaaggt aatcaccggt ctattgaact tttccgcttg tttcatcagt
    31441 cgtaaagctt ttcgatagcc ttcaggatgg ggagaaccaa aatttctgcg gatattttcc
    31501 tgcagatccc gtcctttttg aataccgatc actgttaccg gtttgccatc taatcgagcg
    31561 attccaccaa caatcgcttc gtcatctgca aataaacgat caccatggca ttcctcgaaa
    31621 gaatcgaaga tctcttcaaa aaaatccaag cttgtccatc gttctttagc tcttgctaac
    31681 tgaacgacat catgtgctgt cttatccacg atctatccat cctttctgtg tatgcaattc
    31741 aagaagcgta tggattttct gtttcaattc catgcgggga acaatctgat cgacaaaacc
    31801 atgagataat aagaattcag ccttttggaa atcttctgga agttcctgct tgatcgtctg
    31861 ttcgatgacg cgtcttccag caaaaccgat caagctttgg ggttctgcta gaataatatc
    31921 gccttccatt gcaaaactgg cagttactcc tccggtcgtc gggtccgtta aaacagttag
    31981 ataaaaaaga ccttcattgc tatgccgttt gacagcagca gagatttttg ccatctgcat
    32041 tagagaaaag attccttctt gcatccgtgc gccacctgaa gctgtgaaca agacgactgg
    32101 aagactttcc tttgttgctc gttcgaataa tctggtgatc ttttctccga caatcgttcc
    32161 catacttccc atgataaaat taggatccat cactccaata atgaagggaa tcccctgaat
    32221 ggttgcttta ccagtgagga ctgcttcatg aagtcctgtt ttatcttgca tttttttaat
    32281 tttttccgta tattcgggaa atgctagcgg atctttggtt acaagatccg tatcccattc
    32341 ttcaaaactt ttttcatcaa taatcaaagc tagacgctgc catgcaccga ttcgaaaagc
    32401 gtatccgcaa tgagggcata ctttttcttc accgatgtct ttcgtataaa ggatatgttt
    32461 gcaatttgga cactttgccc acatgttatc aggaacagat ggcgagttag caggtttgct
    32521 ctctctatta ggattgatcc gaatatattt ctttttctta aacagagcca tctatgcgcc
    32581 tcctatctcc gtttctggtg tccaattcgg taaaaattct tcttgtaaaa atgctgtgct
    32641 gtaatcacct gctatgactg caggatgact aatcaaatcc atctgaaatt ctgcgttcgt
    32701 gatgattcct tctgtgataa attcacttaa ggctcgctgc atcttcatta atgcttcaaa
    32761 acgcgtattt ccatggacga ttatttttgc aatcattgaa tcataatatg gcgggatcgt
    32821 atatcccggg taaactgcac tgtctactcg cagtcccatc ccacctgctg gaagcagtaa
    32881 gttttggatc ttccctggag aaggagcaaa atggaaagca ggattttctg cattaatccg
    32941 gcattcgatt gcgtgtcctt ggaatactac ttcttcttga cacacattca aaggctcacc
    33001 ggctgctatc tccacctgtt tttttactaa atcgattcct gtgaccattt ctgttactgg
    33061 atgttccact tggattcgag tattcatttc catgaaataa aaatcgcctt cttcatccat
    33121 cagaaactcg atcgttccgg cattttcata attgactgct ttagctgctc gaacagcagc
    33181 gtctcctagt gcttctcttt ttgtttgtga gatcactaca gaaggagatt cttccagtac
    33241 tttttgattg ttgcgttgta aagaacaatc tcgctcgcct aaatgaatga catgaccaaa
    33301 tcgatcacct aagatctgaa cttctatatg gcgagcagga taaatgattt tttccaaata
    33361 catatcatca tttccaaatg ccgctgctgc ttcttgctga gctgaagaaa aatgctgtgg
    33421 gagctcttct tttgattgaa ctttccgaat gcctttcccg ccaccacctg cagctgcttt
    33481 cagcatcact ggataaccaa ttctgtctgc tatttccaat gcttcttcta ctgtagataa
    33541 tacaccagta cttcctggaa tgactgggac atttgcttct tgcatcaatt gacgcgcatt
    33601 gatcttattt cccattgcat cgatcgttgc acttttagga ccaataaatg tgatattgca
    33661 ctcttcacac atggaggcaa atcggctatt ttcagataaa aaaccaaatc ctggatgaat
    33721 tgcttcggct tttgtcacga ttgcagcgct cagtacttcc tgaacattca gatatgaatc
    33781 aacggctttt gccgggccaa tgcagattgc ttcatctgct aactgtgtat gaagtgcttc
    33841 ggcatctgct tctgaatata tcgctacggt ttggatccct agttcgcggc atgcacgaat
    33901 gatacgtaca gcgatttcac cgcggttagc tatcaatact ttagaaaaca tatttcacct
    33961 atccaatcat aaaggttaat tccgcttcgg ctactttttt accgtctact ttagcgattc
    34021 ctttgcctat tccggctgaa gttttcactt tcaatatctc aacttcaagg tataaggtat
    34081 ctcccggtgt aactttctta cggaattttg ctttgtccaa tccgccgaaa taagccgtct
    34141 ttcccttgaa ttgttcaaga gaaagtaatg caactgctcc tgcttgagcc attgcttcaa
    34201 caatcaatac ccctggcata acaggttctt ctggaaaatg tccttgaaaa aagggctcat
    34261 tgatcgttac atttttctta gcaacgatcc gttctccttc aaccatttct tccactcgat
    34321 caatcaaaag cattggataa cgatgtggaa tgatttcttt tatttcttgt atgttcattg
    34381 ttttccctct ttcctgcttt gcttattttt gctgaatcct aaagagtggc tgtccatatt
    34441 cgacaactga ctcgttttct acaaggattt ctgtgatcac tccgtcggcc tcactagtta
    34501 tctcattcat cagtttcatc gcttcaataa tgcagataac ttctcctttg gcaacttgat
    34561 cacctacttt tttgaaagct ggtttgtcgg gcgctggttg cagataaacg attcccacga
    34621 ttggcgaaac aacctcgatt ccatcaaata ctgccgattc tttttctttc attatttctg
    34681 gagcagttgt tgcttgttca ggtatgacat tgactggctc cgaaactggc aacgtttcgt
    34741 ttgtttgaac catattcatg cctcgacttg ttttattttt attcatatac aattcaaatt
    34801 gaccttcacg caaatcgaat tccgttagcg aggattgatc aaattgactg actaattctc
    34861 tgatttcatt gatatccaaa attattcctc ccagcgtttc atgcacagaa ccgcattatg
    34921 tccgccaaac cctaatgaat tactcattgc ataagtaaaa cttgcaggtt tgctttcgtt
    34981 tttgacaact gtcaagtcaa tctcaggatc ttgtttttct acattgatcg taggtgggat
    35041 aaattgatgt tctaatgcca gcaaagttgc caaggcttcg atcccgccgg ctgctcccaa
    35101 taaatgtcca gtcatcgatt tcgtgctgct gacgtaagta tctctgaaat tttcacctaa
    35161 tgcgatttgg attgcttttg cttctgcctg gtcattggct ggtgtacttg ttccgtgagc
    35221 attgatatat ccgacttgtt ccggctgtac accagcttct tccatcgcaa gcttcattgc
    35281 tttagatgca ccagaaccat ctggagtagg agctgtcata tggtaagcgt cacagtttgc
    35341 accgtatcca acgatttctc catagatttt ggcaccgcga gcttgtgcat gttctaaaga
    35401 ttcaagaact agaacgcctg ctccttcacc catcacaaaa ccattccgat tttcgtcaaa
    35461 cggaatcgaa ccacgattag gatcagttga ttctgagagt gctgttaaag ctgcaaatcc
    35521 agcaatcccc atctcacaaa tcgttgcttc tgttcctcca gcaagaatga catcagaata
    35581 gccatgtttg atgttacgga atgcttcccc aattgaattc gttccgctag cacaagctgt
    35641 tacgatagct gtacaaatac cttttgcacc tacacgcaaa gcaatatttc cagctgccat
    35701 gttggcaatc gccattggta cgaacattgg agaaactcgt tttgcacctt tttcatgtag
    35761 acgaataact tggttttcga ttgttggaag accaccgatc ccagatccga tgatgacgcc
    35821 aaaccggtct tgattcattt tttctttatc taaaccgctc atctccattg cttctaaagc
    35881 agcgtagatt ccatagatcg aaaacatatc cattcgtttg ctatcttttt taataaaata
    35941 tttatcgtaa gggaaatctt tgacttcacc cgctaaggta atccctgttt ctgaagcatc
    36001 aaatttagtg atcggtgcga tgccattcgt cccctctttt aagctattca aaaagctgtc
    36061 tgcgtcattt ccaataggtg aagtgactcc atagccagta attaccactc gattcatttg
    36121 tttgctctcc ttttcttatc cgtgcatgac caatccgcca tcgacattga tgacttgtcc
    36181 ggtgatatat ggattttgtg ctaagaaaac tgctgtttgt gcaatatctt ctacttgtcc
    36241 gaaacgctgc atcggaattt gcttttccgc ttgttccttg actttgtctg ctaaaacttc
    36301 cgtcatatca gttgtgatga atcctggcgc aatggcatta catgtaatgc ctctagttgc
    36361 agcttctcgt gccacagatt ttgttaatcc tactacgcca gctttactag ctgcataatt
    36421 tgcttgacca atatttccaa tcaacccaga tacactagag agattaatga tggccccttc
    36481 tcgctgcttc atcatttttt tcaatacgtg ctgcgtcata ttgaaggttc caatcaaatt
    36541 gatatccaga cattttttga aatcttctgc atccattcgc atcacaagtt tgtcatttgt
    36601 gattccggca ttgtttacta acacatggat cgatccaagc ttttcttctg cttctttgat
    36661 catttgtccc gctttctcat aatcagagat gtcaccggaa actcctacgc attttacacc
    36721 gaatgcttcg atttcttcta tcttttcttt tggaatctct ccgcgaccat tcaaaatgat
    36781 atttgctcca gcttttgcaa aagctaaggc catcgctttg ccgattcctc ttgtactacc
    36841 tgtgataaat acattttttc cttttacatc cataacgttc ctccttatag tattgctatt
    36901 gtttcatcaa atgtctgctt attctcaaca cgcagaactg gtattgtttt atcgattttt
    36961 ttcataaatc cgcttaatac ttttccgggg ccgacttcga tgacttgttc gatgccgatt
    37021 gtttttaact tatggatact ctcatagaaa cgaacaggtt gcatgacttg ctgttcaagt
    37081 agtcccgcga ttgtttcttt cttcattatt tccgttgttg tgttgcttat gataggaaaa
    37141 gaaggttcag agaattgaat ctgacttagg tccttcgcca gtttttttgc tgccggttct
    37201 aaaatagctg tatgaaaagg cccgctgaca tttagaggga tcattctttt gaaccctttt
    37261 tcttttaata gtaaaacagc ttcgtctact gctttttctt cgccaccaat cacgatctgc
    37321 tgaggtgtat tataatttgc aggagatacg atgccgtact tgctagcttc atgacagctt
    37381 tcctcgatcg tttcaatcgg cgcattcatc actgcaacca ttttcccgct tccagctggg
    37441 gcagcttctg tcatataagc gcctcttttt gctactaacg caactgcttc agtgaaggat
    37501 agcgcattac tagctactaa tgccgaatat tctcctaaac tcagtcctaa agctgcatct
    37561 gggatgattc catgctcctt caataagcga taatacgcga tgctgactgt tagaatagct
    37621 ggctgtgtat attgcgtctg atccaaacgt tcattttctg taaagcaaag ttcagccata
    37681 tcgtagccga gaatctcact tgcttcatca aatgtctgct ttacaacggc ttcttcatat
    37741 aaatcttttc ccataccttg atattgtgca ccttggccac taaataagaa tgctgttttc
    37801 atgtttttct ccaatatatc cagaatatat gtttgattct tcctattcaa aaaggccgag
    37861 acattcctat ttcaggaaat gtcccagccc ccaacctaat tttaatgatt atgcagtttg
    37921 tttttctacg taagtcacta aatcttgaac cgttttgatt ccgtcttctg tttcgatttt
    37981 cacgtcaaat tcatcttcaa tttcattgat gatttggaat aaatccaagc tgtcagcttc
    38041 taagtcttct tggatgtcag tagtcaattt gatttcttca gtttcttttc ctaattcttc
    38101 tgcgatgatt tcttgaattt tttcgaatac cataataata tattcctccg atattgtttg
    38161 ctttttattt ttataattta acagtctaca actccatgag aatacttccc catgttaaac
    38221 ctccgccata gcctgtaaat attactttct gctgttttcc taaggtgatc tttccactag
    38281 aaactgcttc atccaataag atagggatgc ttgcagcaga tgtattccca tatttatcca
    38341 tattggtcag gaacttttct tgcggcatct ttacttttcg ggcaattttc tcaataattc
    38401 tgaggtttgc ctgatgcaaa agcagataat caactggttt gtctttcatg acttcttgga
    38461 tattgtttgc aacgtctcgt acggcaaaat caaaaatatc tctgccagtc atttgcaaat
    38521 aatacgaacc ttctgaatct tctgaataga acggattttt attttgctgg tagccagcgg
    38581 tcaatgagct acttctggta ccgtcagctg ctaatttttc tttcagcaat tttttctgtg
    38641 gattcgcttc taagagaatc ccacctgctc catcgccaaa caacacagca gtcgtacgat
    38701 cagaccaatc gattagctta gatagtgttt caccaccaat caccagtccc ttagttgagc
    38761 cgcagcggat cattttttca gccatgctta acgcataaac aaatcctgag cacgcagcac
    38821 tgatatcaaa agcgatagca tgagttgctc ccaatttccc ttgtacttgt gctgctacag
    38881 atggtgtcgt gtaatcgggc gacattgttg ctactaaaat aaaatccaaa tctttagggt
    38941 ttagattttt ctgttttatc aatttttccg ccactaaaat gcataaatca gaagtctcct
    39001 gatttgttac acatcttcgt tcacgaatac ccgtccttga cgaaatccat tcatcagagg
    39061 tatccatcat cttggaaaga tcattattag taataatctt ttcaggaagg acgctggctg
    39121 ttgcagtaat cattccaaat tgttccatta aatatcctca cttatagtct tgcaagaagt
    39181 cgtgcaagtt tttcagtgca tccagcaagg catgctgttc ctccgtagcc attccgtcta
    39241 agatgttctt gaccatttca cgatgaaaat gctgatggac ccgaaatagt aactttcctt
    39301 ttttcgttag tcccaacttt acaacgcggc ggtcatcttc actgcggata cgttcgacat
    39361 agcctttttt tactaacttg ttaatagcag tggtcaaggt cccaacagta attgatagtt
    39421 ctttggctac ttctgaagtt gtttttttct tgtacatccc gattgcctcg atcgtgtgca
    39481 tctctgtgat tgacagatct ttgaattgag attttttcag ctcagactct tcgattgtca
    39541 aaatatcatt gaagacacta acaagataat catttactgt ttttaaatct ggttccatgt
    39601 tccaccgtcc actaattagt ttgattatca aatcttttga tgttcaaact atatcttaac
    39661 ttttttcaaa atgcaacctt aaaagatcat ttttttacta tatgagcttt ttttaagatt
    39721 ttactcattt aaaacaactg ataaatcagc atttataatt tcttttatta gaaaaatcat
    39781 ctatctcaca tattttgatt atcaaagtat tttctgtgaa cagaactata gaattcccta
    39841 aaacttgtcc attatttcaa aatttgttat agtcttttta ttcaaagcgt aaaaggagat
    39901 cctatgttaa aagaaaaaat gaaaactctc cccatgctgc cgggtgtcta tcttatgaaa
    39961 gaccgagatg gtaaggtcat ctatgttggt aaagcaaaac ggctcaaaaa tagagtaagc
    40021 agctattttc atcagaataa acagcattca aaaaaagtat tacgtatgat tcatcatata
    40081 acagattttg atttcgtcgt agtagacacg gaattagatg ctttattgct cgagtgtcaa
    40141 ttgatccaac attaccgtcc tttttataac cgacaaatga attatttcag taattataat
    40201 tatgtacata ttaccaataa gggatttgta ttaacagata ctcctacggc tcgaacatac
    40261 gggccttttc gtctctataa aaaaatgccg tctattttgc gtataatgga agaaacttat
    40321 caaatgcctt ggttgtctga aattagtttg ttagctttgc gagtccagct tcctgaccta
    40381 caggaaatga cttttgaaca gaaaaaaaag gaactccaag ggctgtttca aggccgaaat
    40441 aaaaagctac tgacttactt gaaaaaaaga caacaacatt tcatctatca gttgaatttc
    40501 gaaaaagccg gtatgcttca aaaagatatc gaattagtta cttattttat tagacggatc
    40561 caggaacaaa agcagttttt aagaacacca tcgctcacct tcagcatgcc attagcagca
    40621 gatgagagtc agaaaaagca ctacctcgtt tgttatggtc aacttgcaga aacaatgatt
    40681 acctctggtg acgtttctcc tgacttctat tatgaaaaga aagaagctca tttatctttg
    40741 aaacgtcaat tgtcaaaaga agaaatcgat cctgtacaaa tcttgatcag ttaccgcaaa
    40801 aaattagaaa aagaacagtt tgaaattgaa ctgttaaaca aaaaagaagc tgaaaagcaa
    40861 ctaaattagt tgcttctcgg cttcttttag gcatcttcaa cttcaaatgt caattatcct
    40921 aaaatttatt ggattaagtc atagatttcc atcgctacga tatcgatatt atcaaattcg
    40981 tattgctgat gagtatctgt ttcagttaat tcaaatgtat cggtcgcttt atcataagtt
    41041 actgtacact tctctacgcc ttctttttca aaacggcgaa cttgcagttc attatctgct
    41101 gactcgacca tagcctccag tcgttttatg attgcgacta attgtgaatg tgtcatcgga
    41161 ggtcctcctt ttcttatttc tgttatattg tatcaaaagc atagcctact tgcattgatt
    41221 ttctctaaaa aaactcgttt tttatgattt tttttctggt atttttcctt caggccacca
    41281 aagtttgatc aaagcttggg ttccgtcatt ctcaaaacct ttatctgcca actcttcata
    41341 tagtttcaat gcttgggtag ttgctggcaa tacaagatcc attttttctg cttcttctaa
    41401 tgcaatcttt aaatctttga taaaatgttt gacaaaaaaa ccaggtgtgt aatcttcttt
    41461 taaaatacga ggagaataat tgcttaaaga ccagttagct gcacttccac ctgaaagcgt
    41521 ctcaatcact ttctttaaat caagtccgtt tttttgtgca tagacaagca tttccgtcat
    41581 tcctgtcatc gtacctgcaa tcatgatctg attagccatt tttgtatgct gacctttccc
    41641 agcagaacca tgcaatgtaa atgtcgtacc aaattctttg aataaaggca gtacttgatc
    41701 ataaacggct tcttctccac cgaccatgat cgtcagtgta ccattctttg ctcctaagtc
    41761 accaccggat accggtgcat ctaacgcatc tgcgcctttt tcttttgctg tttttgcaat
    41821 tttttctgcc aggcttggtg tacttgtagt caaatcaact aaaatatgtc ctgagatatc
    41881 tgcagaaaaa atccccgact gtccatagta gatttcttct acatctttgg ggtaacctac
    41941 cattgtaaag agaatattac tttgttctgc taccgctttt ggtgtatctg cccagatagc
    42001 tccttctgtt actaaaggat cagcttttgc ttttgtccga ttatagacag ctacttcgtg
    42061 tcctgcttct agtagatggc gtgcgacagc acttcccatg acgcctgttc cgataaaacc
    42121 aagtttcatt ttttcgacct cctaaaaatc aaaaatcctt gcttctatgc tagtatacgc
    42181 tagaaacaag gattttttca taaaaaatgt ttgaatttta tcttttaaat gaatttaatt
    42241 ttattttgat tcgttcaatc gagtcttctt cttcttttct tcgcatctct tcttcatgat
    42301 aaacaaccat gtcttgataa aattcgatca tagcttcgcc gaaatgtgta gatgaaatat
    42361 cataaagttt agcttctaaa acttttggat ctttaggaac ttcactggaa atataatcaa
    42421 taagtgctgg tgcaaagtct tcgtcggttt caaaagtttt ccctaatgaa ggatgatcga
    42481 acaatcggtt caaataagca tttccttcca cgacacaagg tgttccggct gccatcgctt
    42541 ctgtataagt aagcccttgt gtttctgaag tagaagcact gacaaaataa tctgccgctt
    42601 tataataaag tgctacatca ttgttgtcca cttctcctgt gaactgcaca aattcttcta
    42661 actgcagttc tgagatcaat tcctctaact cttctacata aggtcctttt cctacgataa
    42721 ctaatctggc gttaggataa gcggagatga cctgaggaaa cccattaatc aaggcttgga
    42781 tatttttctc ataagaaatc ctgcttaaag aaagaatcat caaatggttt tcctgaagac
    42841 ctagtgactc ccttaatttg ctgatatcct gctgagtgat atcagaacgt ttgaattttt
    42901 caatgtcgat accagtagga atcacgcgaa gcggtgctat tacaccatag ctgcgtaatg
    42961 tatcaataac acgttcactt ggacaaacta cacctgtcgt atgatttgca aataatctag
    43021 acaagtattt tacatgggat tgcctgatca cttttccttt accgatataa tgaaggtagt
    43081 cttcatacat cgtatggtaa gtatggatca gaggtatttt caacttctta gctaccatct
    43141 tcccaagtat ccctgctccg aattctgtat gggtatgaat aagatctagt tctagttctt
    43201 tggcaaccaa ataagcatac cacatgcctc taacaacaac tcttcgatcc ttgaaagaaa
    43261 taaatggtac acttggcatt cgaatcacat ctttttccaa cttatccgca ttaggatcgg
    43321 tcgttgtaaa aatatagact tcatgcccat gtctttctaa ttcttgtttt aatgttttga
    43381 tcgatgtagc aactccgctg acttgcggaa agtaggtatc ggtaaaaaag ccgattttca
    43441 tgtttttcgc ctccaaacta gtccttgacc tgatttactt tttttaattt gctagagact
    43501 ttttcattca gtacactttc gtatacattt ttaagttctt caccgatttt attgatactt
    43561 cgctcttttg ctgtttgata accggcttgt gtcgtactcg gtagttcttg attggtaatc
    43621 tgttggatca gtcggataaa ttcttcgttt gtcttcccca tatagcagtt cttgctatct
    43681 tctaaccagc cattatacac tggaatatct cgaacaagta cgttttgttt gcttgctaaa
    43741 gcttctaaaa caacgatccc ttctgtctct tcataagaag ggaaaaagaa tagatctgca
    43801 cctgaatacg caccttctat gatctctcca cgaatgtaac caggaaacag gacattttca
    43861 ggatgatctt cttttacaat tttccggatg ttccgaggaa tcgagtacat gggaacatga
    43921 ccaaaccaaa taaatgtgta ttcgggcatc ttcttagcaa tttctacgaa atcaatgatt
    43981 cctttacgtt cgaaaaacaa accgacacaa atgattactt tttgatccgg agacagtttg
    44041 aaatattctc tgaacttttg ttctttcatt ggatcagggt gatatttctc taagtcgatc
    44101 ccattggaaa tagcttgaat cggcacacgg ataccatagc tttccaacaa ctgttttgaa
    44161 taaggtgttg gcgtgatcag atagtccgct ttttggtaca atcctaccag atattttttt
    44221 acgataggag aaagctggtt cgatccgata aaggaatttc ggaaatcttc ctctgtagaa
    44281 tgcgcatgat agacaacttt ttttccttct cttctggctt tattgaccat attatgacta
    44341 ttgattccgt atgtattgat gtgcaggatg tcataatctt ctttttcatc tagtgtataa
    44401 gagataccga cttccgtcag agcacgtttt tgatgatcaa gcgcacgccc gattccagat
    44461 tttgcaagca tcttttcact ttcaaaatat aataatacct tcaccttacg tcccccttca
    44521 cttatatagt ataacatagc ctacaaactg tcactcaaac ttaagcccta tttttgtcta
    44581 ttcttactga caaaaacgtt ttcttaaaaa agaacaaaaa aactggcgta gctcttttac
    44641 aagccacacc agcttttgat acgttgttta ttttacatat tcatgaacaa gttcaacgac
    44701 ttcttccatc gtatcgcatt ctttcaatgc acgatcagca agttcagcca ttttcgctgt
    44761 gtccaagcgt ttcattaaac tacgcgtttt aagaatagat gtcgcactca ttgagaactc
    44821 atctagaccc atacctacta gcaatggaac agctgtttga tctccagcca tttctccaca
    44881 catacctgcc cattttcctt cagcgtgtgc tgcatcaatt acatttttga tcaaacgtaa
    44941 aattgatggg ttatatggtt ggtacaagta agaaacgcgt tcgttcatac ggtctgctgc
    45001 cattgtgtat tgaatcaaat cgttcgtacc tacagagaag aaatctactt cttttgcaaa
    45061 cttgtctgct aagactgctg ctgctggaat ctcgatcatg atgccgactt ggatcgtatc
    45121 agatacttcc ttgccttcac ttatcaattt ttgtttttct tcttcaaaga tcgcttttgc
    45181 tgcgcggaat tctttgagtg tagctaccat agggaacatg atacgtaaat taccatgaac
    45241 agatgcacga agcaatgcac gcatttgtgt acggaacatt tcgtcgcctt gttcagataa
    45301 actgatacgc aatgcacgat atcctaagaa tggattcatt tcatgaggta attgcagata
    45361 tggtagttct ttatctccac cgatgtccat tgtacgaaca actacaggtt ttccttccat
    45421 accttctaat acagctttgt aagcttcata ttggtcatct tctgttggga agtctggaga
    45481 atccatatac aggaattcag tacggtacag accaactgct tctccaccat tattatggac
    45541 accaactaga tcttttggtg ttccgatgtt tgcagctaat tcaaaatgct tgccgtcagc
    45601 tgtgacagtt tctgcatttt ttaatttttc ccattctgct ttttgtgctg cgtaatctgc
    45661 acctgctttt tcaaattcag ctttttgttc atctgtagga tcgatgatta catcgccttc
    45721 gatcccgttg acagccaaaa tatcgccttc tttgacttta gcagtaattt cttttgtccc
    45781 aacgattgct ggaatttcta aagaacgtgc catgatagca gaatgtgaag tacgtccacc
    45841 aatgtctgtt acaaacgctt ttacaaaatt gcgatctaat tgtgctgtat cacttggagt
    45901 caagtcatgt gcaacaacga ccacttcttc gttgatcatt gatggatttg gtaaagtaac
    45961 gcctaataag tgcgctaaaa tacgtttagc aacgtcacga atatctgcag cacgctcttg
    46021 catataagca ttatcttcca ttgcttcgaa cataccgata tacatatccg ttacttcttt
    46081 tagcgctgat tcagcattta cgctgttgtc tttaatattt tgcttgattt gacctaccat
    46141 ttctggatct gaaagaacca tcaaatgggc atcaaatact tgcgcttctg cttcacctaa
    46201 gctttgcgct gctttttcac gaatttgctg caattcttca gtagatttag ctaatgcagc
    46261 atccaaacga gcttcttcag ccgcagtatc ttctactgtt gccttactga atgttaaatc
    46321 cggttgaact agcaggtaag cttttgcaac ggctacaccg tcactagcgg caatcccttt
    46381 tagcatttca accattattc agataagcct tctttcttca ttgtttcaac gattgctgcc
    46441 attgcatcag cttcgtcagc accttctgca gtaatagtaa catcagaacc ttgacctaca
    46501 cctaaagaca taacgcccat gattgatttc aagtttactg atttaccttt atactctaag
    46561 tttacatcag agttaaattt gcttgctgtt tgtactaata gtgtagctgg acgagcgtgg
    46621 atcccagttt ctgctactac gtgaaattct ttcttttcca tattaatcgg tctcctttaa
    46681 gtgagtgttg tttttatgtg agggttttct tttttagtaa ttcagagaat cctaacaaat
    46741 gccacccttt catctgtaaa gattaacatt ttttttcgtt agatacaaca gttttcattc
    46801 aatttcagat aaaagtattc aaattattcc ggattctttt tcatcctttt cttcacattt
    46861 tataacaaac gtgtttattt cctttttctt gtcgctttct cttctcctga cgtttatcat
    46921 tctttccttt gaccctcttt gttttcatat gaaacgaatt acttgcttcc ctttttattt
    46981 ttagtataat aagagtcaaa ggtcaggaat ggtcaataga gatttcacct tttctacctc
    47041 ataaatctct taaaaaacta ggggttattc ttttacctca tgaaaaacga gatgtaaaat
    47101 atggatgtac ccatttttgt gaaaggacgt gaatgattca tgctttgtca aaactgcggc
    47161 aagaatgagg caacgattca cttgtatgcc actgtcaatg gtcagcggac acaactcgat
    47221 tactgtcaga gctgttatca aaaaatcaaa aatcaacaaa atggaggtct gactaatatg
    47281 gcccaaaatg atccatttgg atttggcagt ttggacgatc ttttccgttc catgtctcgc
    47341 caaatgcaac agcaaggaaa ttatgagcaa acaccaccaa cacaatttgg cggaaacaac
    47401 aacttcaatg gtggtcagcc acctcaaggc aatacagaag gtttattggg agaatacgga
    47461 atcaatatca cagaacaagc acgacaaggt gatatcgatc ctgtgatcgg acgcgatgac
    47521 gaaatcaaac gagtcattga aattttaaat cgccgaacca agaacaatcc tgtcttgatt
    47581 ggagaaccag gtgttggtaa aacagcagtt gttgaaggtt tagcacaaaa aatcgtagat
    47641 ggtgatgtac cgcaaaaatt aatggacaaa gaagtcattc gtttagatgt cgtatcttta
    47701 gtccaaggta ctggtatacg aggacaattt gaagaacgta tgcaaaaatt gattgaagag
    47761 atccgtcaag cagaaaatgt gatcctattc atagatgaag ttcacgaaat agtcggtgct
    47821 ggttctgctg gtgatggaaa tatggatgct ggtaatattt taaaaccagc tttagctcga
    47881 ggagaattgc aaatggttgg tgctactacc ttaaatgagt accgcatcat cgaaaaagac
    47941 gctgctttag aacgtcgtat gcaacctgta cgggtagatg aaccaactgt cgaagaaacg
    48001 atcagtattt tgaaaggttt gcaaaaacgt tatgaagact atcatcatgt aaaatatact
    48061 gatgaggcca tcgaagcagc cgcaacttta tccaatcgtt acgtccaaga tcgcttcttg
    48121 ccggataaag ccatcgattt gctagatgaa acaggttcta agaaaaactt gacgatccaa
    48181 atcgttgatc ctaaaacaat cgagaaaaaa ctgcaagaag cagaagaaca aaaagtttta
    48241 gcttctcgag aagaagattt cgaaaaagca gcttattatc gcgatcagat caataaactt
    48301 caaaaaatga aagaacgtca gctcactgaa gaggaaacac ctgtgattac cgaaaaagat
    48361 atggaaaaaa tcgttgaaca acggacaggt attccagtgg gtgaattaaa agaaaaagaa
    48421 cagacacaac tgaaaaactt agcagatgac ttgaaagctc atgtcatcgg acaagataac
    48481 gctgtagatc gagtagcgaa agcgattcgc cgaaaccgtg ttggattaaa caaacagaat
    48541 cgtccaatcg gctccttctt atttgttgga ccaactggtg taggtaaaac agagcttgcg
    48601 aaacaacttg cctacgaact attcggttca caagattcaa tgattcgttt cgatatgtct
    48661 gaatatatgg aaaaacatag tgtctctaaa ttgattggtt ctcctccagg ttatgtcgga
    48721 tacgaagaag ctggtcaatt aacagaaaaa gtacggagaa atccttacag tcttgtcttg
    48781 ttagatgaag tagaaaaagc tcatccagat gttttgcata tgttcttgca aatcttagat
    48841 gatggtcgat tgacagatgc acaaggaaga acggtcagct ttaaagatac gatcatcatt
    48901 atgacaagta atgccggaac tggtaaagta gaagcaaacg ttggttttgg tgcggcacgc
    48961 gaaggtgtta ctcgttctgt attgaaccaa ttaaacaact actttacacc agaatttctg
    49021 aaccgttttg acgggatcat cgaattcagt gcattatcaa aagaaaactt gatgacaatc
    49081 gtcacactaa tgctagacga tgtcaaccaa atgctggcag cacagcaact tcacatcgaa
    49141 gttcctacga atgtcaaaga aaaattagtt gacttaggct atgatccatc tatgggtgct
    49201 cgtcctcttc gacgcacgat ccaagaacaa atcgaagatg gtatcgctga attttatctt
    49261 gatcaccctt ctatccatga gttgaaagca aaactggata aagatggaaa aatcatcgtt
    49321 acttctaaac cagaacgttt ggctaaagaa tcagccgaag aaacggctga ataaatccag
    49381 ttttatagcg tgagacggta tttctttgag aaatgccgtc tcattctttt ttcagaaaag
    49441 tcaaaatact gttcatttta taaaaaagaa attataataa gagaaacaag caattaaaaa
    49501 tacataaaag aggtgagcgc catgaaattg gtaaatgtaa caaacagcca ttcccgtctt
    49561 gtattaaacc agcttgaaaa cactgatgcc catctagtca aggtctacac agccggaaat
    49621 accactattg tctacactga agcccctgaa cataatgaaa ttctgctgat caatgacaaa
    49681 cgtaaaatcc agccgaaaga aatcgaagat gctaaaaatt atttcttaga taaaatcaaa
    49741 gacgccgttt accacgagga tgaaatcaaa gtaatcgaat tggcaggcct tgttgaaatc
    49801 tcgattccaa aacatgaatt aggcgctaca ttagccgtgt aaacaaattt tgaacataat
    49861 aattaaagag cgtgggacaa aagtaaa
//
LOCUS       DAFEEZ010000013        47854 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000013
VERSION     DAFEEZ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.013"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(38..1189)
                     /locus_tag="LP245_000861"
     CDS             complement(38..1189)
                     /locus_tag="LP245_000861"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBL1518797.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1202..1639)
                     /locus_tag="LP245_000862"
     CDS             complement(1202..1639)
                     /locus_tag="LP245_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1518798.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1654..3420)
                     /locus_tag="LP245_000863"
     CDS             complement(1654..3420)
                     /locus_tag="LP245_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBL1518799.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3684..4361
                     /locus_tag="LP245_000864"
     CDS             3684..4361
                     /locus_tag="LP245_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518800.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4364..5491
                     /locus_tag="LP245_000865"
     CDS             4364..5491
                     /locus_tag="LP245_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518801.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5691..6131)
                     /locus_tag="LP245_000866"
     CDS             complement(5691..6131)
                     /locus_tag="LP245_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1518802.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6142..8175)
                     /locus_tag="LP245_000867"
     CDS             complement(6142..8175)
                     /locus_tag="LP245_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL1518803.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8177..9880)
                     /locus_tag="LP245_000868"
     CDS             complement(8177..9880)
                     /locus_tag="LP245_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1518804.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9974..10924)
                     /gene="manA"
                     /locus_tag="LP245_000869"
     CDS             complement(9974..10924)
                     /gene="manA"
                     /locus_tag="LP245_000869"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBL1518805.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10963..11988)
                     /locus_tag="LP245_000870"
     CDS             complement(10963..11988)
                     /locus_tag="LP245_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBL1518806.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12197..13066)
                     /locus_tag="LP245_000871"
     CDS             complement(12197..13066)
                     /locus_tag="LP245_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBL1518807.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13525..15417)
                     /locus_tag="LP245_000872"
     CDS             complement(13525..15417)
                     /locus_tag="LP245_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518808.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15414..17141)
                     /locus_tag="LP245_000873"
     CDS             complement(15414..17141)
                     /locus_tag="LP245_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518809.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17157..17807)
                     /locus_tag="LP245_000874"
     CDS             complement(17157..17807)
                     /locus_tag="LP245_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBL1518810.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18011..18307
                     /locus_tag="LP245_000875"
                     /pseudo
     CDS             18011..18307
                     /locus_tag="LP245_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            18479..19099
                     /locus_tag="LP245_000876"
     CDS             18479..19099
                     /locus_tag="LP245_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBL1518811.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19191..20357)
                     /locus_tag="LP245_000877"
     CDS             complement(19191..20357)
                     /locus_tag="LP245_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1518812.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20369..20722)
                     /locus_tag="LP245_000878"
     CDS             complement(20369..20722)
                     /locus_tag="LP245_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBL1518813.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20850..21872
                     /locus_tag="LP245_000879"
     CDS             20850..21872
                     /locus_tag="LP245_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBL1518814.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            21891..22052
                     /locus_tag="LP245_000880"
     CDS             21891..22052
                     /locus_tag="LP245_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518815.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(22311..22745)
                     /locus_tag="LP245_000881"
     CDS             complement(22311..22745)
                     /locus_tag="LP245_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518816.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22855..24714)
                     /locus_tag="LP245_000882"
     CDS             complement(22855..24714)
                     /locus_tag="LP245_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL1518817.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(24832..25992)
                     /locus_tag="LP245_000883"
     CDS             complement(24832..25992)
                     /locus_tag="LP245_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBL1518818.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26299..27723)
                     /gene="araA"
                     /locus_tag="LP245_000884"
     CDS             complement(26299..27723)
                     /gene="araA"
                     /locus_tag="LP245_000884"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBL1518819.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27739..28437)
                     /locus_tag="LP245_000885"
     CDS             complement(27739..28437)
                     /locus_tag="LP245_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBL1518820.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28394..30055)
                     /locus_tag="LP245_000886"
     CDS             complement(28394..30055)
                     /locus_tag="LP245_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBL1518821.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30273..31673
                     /locus_tag="LP245_000887"
     CDS             30273..31673
                     /locus_tag="LP245_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBL1518822.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31925..33004)
                     /locus_tag="LP245_000888"
     CDS             complement(31925..33004)
                     /locus_tag="LP245_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1518823.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33090..34049)
                     /locus_tag="LP245_000889"
     CDS             complement(33090..34049)
                     /locus_tag="LP245_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBL1518824.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34061..35572)
                     /locus_tag="LP245_000890"
     CDS             complement(34061..35572)
                     /locus_tag="LP245_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBL1518825.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DRFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSRYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35594..36157)
                     /locus_tag="LP245_000891"
     CDS             complement(35594..36157)
                     /locus_tag="LP245_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBL1518826.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36163..37026)
                     /locus_tag="LP245_000892"
     CDS             complement(36163..37026)
                     /locus_tag="LP245_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1518827.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37040..37936)
                     /locus_tag="LP245_000893"
     CDS             complement(37040..37936)
                     /locus_tag="LP245_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1518828.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38111..39400)
                     /locus_tag="LP245_000894"
     CDS             complement(38111..39400)
                     /locus_tag="LP245_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1518829.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39372..40889)
                     /locus_tag="LP245_000895"
     CDS             complement(39372..40889)
                     /locus_tag="LP245_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBL1518830.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            41087..41977
                     /locus_tag="LP245_000896"
     CDS             41087..41977
                     /locus_tag="LP245_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBL1518831.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="LP245_000897"
     CDS             complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="LP245_000897"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBL1518832.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(42886..44358)
                     /locus_tag="LP245_000898"
     CDS             complement(42886..44358)
                     /locus_tag="LP245_000898"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBL1518833.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(44995..45357)
                     /locus_tag="LP245_000899"
     CDS             complement(44995..45357)
                     /locus_tag="LP245_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBL1518834.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            45580..46332
                     /locus_tag="LP245_000900"
     CDS             45580..46332
                     /locus_tag="LP245_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1518835.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(46472..47395)
                     /locus_tag="LP245_000901"
     CDS             complement(46472..47395)
                     /locus_tag="LP245_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1518836.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(47410..47682)
                     /locus_tag="LP245_000902"
     CDS             complement(47410..47682)
                     /locus_tag="LP245_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518837.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        13931 a         9944 c         8260 g        15719 t
ORIGIN      
        1 aaaaatttcg tcacattccc ctttttcgta tcctatttta agcgacttgc ttggcataac
       61 ggttcacgtt ttgcttgata ttcccgattg ttttcggatc attgattcct gtgacttctt
      121 gaatcaattg ttccaagttt tcatggatct tcatttcatg caattgacgg ctttgttcat
      181 cttcaggatc atagtaatta aaaataatcc ccattgttgc cgtcaaatgt gggcaagtca
      241 agttatgttc ttgtagttct ctcactggac gtgtaaatct ttcttgataa cctaacttac
      301 gtaatggtgt ccgagcgaca cgtgtgatcg catcagagat atttttgttt tggaagcgat
      361 gaatgatttt ttcaatatac gcatgatgct gctctgcatc aaacccccat ttggcaatca
      421 gcaaacttcc tgtttcctgc aaaactgatt ttaattgtgc cacaactaac gcatcttgca
      481 ttgcttcatc aatggtctgg taacctaaca aggcacctgt ataagcgaca gtcgcatgac
      541 cagtattgac actaaatagt ttgcgttcga tatatggttc tagatcatct acatataaaa
      601 ccccttttaa ttggattttt ttattttttc tttggctatc gtcaatgacc cattctttga
      661 aaggttccac ttggacgaat aaaggatctt catggtgttg taatgggacg attcgatcga
      721 ctgctgcatt tggaaagccg atatatttgt cagtaaatga tgtttccgga agatatttat
      781 acacttcttt ttctagaaat gctgaaccgc caatcatatt ttcacaggca atgatatcta
      841 aagatgttgt gcttccttcc ttttctcttt cttggatacc ttttgcaatc aactcagcaa
      901 taaaaggtaa gatattcggg ccaatggcgg tagtaactaa atctgcttca gcgatttctt
      961 ggattacttt ttctggattt gtttgattgt tgattccttt gacatttttt acagtgattt
     1021 tttcttttga ttcatctgct aattcgattt cgtattcttt tctttcattt aaagcatcaa
     1081 tgatcgtgtg attcacatct acgaaagtaa tctcaaatcc attagctgcc aaaacctctc
     1141 caataaatcc tcgaccgata tttcctgcac caaaatgtac tgctctcatt tttctctctc
     1201 cttaagcaat tgctagattt tccgttactt cttctttgct gagcgcgtct gctagctgga
     1261 caacattgtc catatcactg caataaagtg cgatttgctg tacaagttgc aaatgctcat
     1321 ctccgactcc tgcaataccg aacaaaacag tcgcaatctt ttcttcttct tcggtaccaa
     1381 aatctacacc atctggtact tgaacgacac agatgccgga ttttttcaca tatttttttg
     1441 cttcatctgt tccatgagga atcgcgataa aattccccat ataaacagat aacattttgt
     1501 ctctatctac catggcatcg atatattcct catcaacgca ccctgcttct acaagcatct
     1561 gaccgcaata gcggatcgct tcttctttgg ttttaaaaga tcgattgagc tcgatcatgt
     1621 cgaatggcaa actttgcatg ctgttttcct cccttaagct gtctgtttca aatattgtgc
     1681 aatcgattcg tatttttgcg gattgaccat gctgttgact gataaatgaa tggattgagg
     1741 tgcagccatc tgtacttttt ccgctaaact ttctttggct acgatcagtg aatcaggttc
     1801 atcttttaaa tcttggatat tgacttttct taacgggata gttaaatggt tcttgtctaa
     1861 tatatctttg agcacggtca tccccattgt tgctgatccg gaacgatcat cgtggacaag
     1921 tagaatctct ttgatttgtt tgatgtttgc tgaaagaaac tcttctgctg gctcattctc
     1981 aatttcagaa actgatgttt tctgcttgct gcttaattct tgaatgattt catcatatcg
     2041 aggtgaattc aaaaagtttt ctactgagac aaaacgcgcg ctcggtgctt tttgttttgc
     2101 tctttcttgt agttcgacct gagtaacgat caatgtattc gagtcatctg tcagttggct
     2161 gattgcttga ttggtcaccg tttgaggcaa gtctgcttcc tgtacttttt ttctcaagat
     2221 cgaagcgccc atcgcacttg atcccattcc tgcatcacaa gcaaaaatga ttttttgtac
     2281 gccagagaat gtagctcctt gaggaatacc ttgggcacct ttggaagctt gcttagctgc
     2341 ctttgtctct tgaacagatt tttcgaagtc ttcatttgta tctttcgcat ccgctttcaa
     2401 aattactgca gaaataccaa acgaaacagc tgcggcaaca atcacgccca aaataacagg
     2461 aaggtaagaa ttgaacggtg tcatcgctag aatcgcaatg atcgaccctg gagaagctgg
     2521 cgctcttagt ccagcatcca tcaattggaa aatgaaactt cctgacattc ctccgcctat
     2581 aactgataag aataataacg gtttcatcat aacgtaagga aaatagattt catggatccc
     2641 gcctaaaaag tgaatgatca tggctcctgg tgctgaagat tttgctgctc ctttgccaaa
     2701 caaagtaaaa gcaagtaata cgccaagtcc tggaccagga tttgcttcaa gcaagaatag
     2761 aatagatttt ccagcctctg ctacttgttc agttcccaat ggtgtcaaaa tcccatgatt
     2821 gattgcatta ttcaaaaata agatttttgc tggttcaata aaaatacttg tcaatggaat
     2881 caaatgggca gataaaatga tctctacacc ttttgccatt gcttgagtca atgcatcgac
     2941 aactggacca atcgcagaaa aacctaataa cgctaatcca aaaccgataa gacctgctga
     3001 aaaattattg actagcattt caaaaccgga tttgatccgt ttttggaata gctgatcaaa
     3061 tttcttgatg gcatatccac caagaggtcc catgatcatc gcgcctagca tcattggaat
     3121 atctgttccg acaatcacac ccatcgttgc aattgcccca acaactgatc cgcggtcacc
     3181 agcaattact tttccgccag tataaccgat caataaagga atcagataag ttagcattgg
     3241 gcttaccatg gtagccaaag cctcatttgg taaataacca tctgggataa atagagccgt
     3301 taatacaccc caggcaatca gtgctccaat atttggcatg accatgcttg ataaagtact
     3361 gcctaatttt tgtaccctcg cttttagcga aatgttgttt ttgggaatcg tccgttccat
     3421 tttgtctctc cctctctcct tttgatactc taattgtatc cgcttactaa aaagagaaat
     3481 agtcgtactt tggcacgaaa ctttgtgcca aaggtttgag tatgtcagca aaataaaaag
     3541 atttcggtat cagaaaactt caattttaaa taaaactgtt attttaattt ttttataata
     3601 tgcaaacaat aacttttgtt agcatttaat ttagatgttt tccattctat tatgttatta
     3661 aattttatat tggaggccta tctatgacat tactgatcaa aaacatgaac atgaaacgtg
     3721 gtaaaaaacg tgtgattcga caattgaatc ttttagtaga atcaggagaa gtagctgctt
     3781 tgattgcccc gaacggattt ggcaaaacaa ctttgctgaa tggcattgcc caactgctgc
     3841 caacaactta tgatcaattg tcccttcaca acatctctcc tactgcttat acagattatc
     3901 gccggtcttt cttttttcta gaatcaacga atcagttatc cgactatcta tcggctgttg
     3961 attatttgac tttgatcaaa tactattggc agagcaaagt agaatgccaa actgttttcc
     4021 aacgattgaa gatgactgag taccttactt tgccgattgg aaaaatgtct ctaggaatga
     4081 aacaacatgt cttgcttgct gcttacttga tcagtgattc atctgtcatg ttattcgatg
     4141 aaccgttgaa cggattagac ccaggaagta ttgatatctt gaatagcctc atcagacaat
     4201 ggcagaaaga ggggaagacg attcttcttt cttcccacgc tatcgcgaat atccaatcga
     4261 tttgttctaa agcatgtttt ctaaaaaatg gagaaatcgt cacagaatcc tcaaatatgg
     4321 aagagatttt agctatttat cgtaaattat atgaggtgta actatgtctt tacttacatt
     4381 tgaacgcaat ctcttactaa aaaacaaagt aaacttttta tttcctctat tgttggtcgt
     4441 gctctttgca ttcccacttt tttttgatca taaacttgct tatacagaat tcgatgaact
     4501 gaatcataac tatgaagaga tgcaacgttt gattgaaacg ttgaaagaag atgagaatga
     4561 gaaagaattt gtggaaagtt tagagaaaag caacaaactg atcgaagcaa tcttacatgc
     4621 aaaaaacaca gggaatgtcc agcaaatggt cgaagcaact tatcattatg aaaaagatat
     4681 actggatcga ctgatttctg gtcaaagaca aggaattcca atcattgaac aacaaaaacg
     4741 tgtcgagttg ctccgttata tgaaagaaca tcagatccaa agatattcta tttttgactt
     4801 gccagcgcat ctccctttag caaattacta cgaaaatatt ttttcaggaa tgatttctag
     4861 ttttttgatt ttatgtataa ccgccttgtt tctttcttcc atcatctctt atgaaaaaag
     4921 aaagcaggta atctctctag tcaatctatt accggatagt atggtaaaga aacatagcat
     4981 ccgttttacc atttattatg gtgcagctat gctaagtctc gtgatgccat ttttgatcgt
     5041 ctctatacta gtaataatca aaaatggttt gggagacttc cgttatcctg taggaacgat
     5101 cattggtcag gagatacgaa tccttccgat gtatgagtat cttttccaga gctttctgtt
     5161 cctgttgttg tgggtgctct ttttaagtac aatcagtttt cttctatctg ctttatttga
     5221 acattctcta gtcaatcttt taggtacact tctttgtctt ttcttagcag agtatcgctt
     5281 gttttcttcg attggatgga tagaatcaat cagtcattac ttgccaactt cttatgttga
     5341 ttttcaaaat gtgatcatag gaggagatat tttctcgcca ctagcttcag aacaggttac
     5401 tttcatgaat ggtatcttga cacttggtat atggagtatc gttttattat tcataggtat
     5461 gggcactatc tatataaaaa agagctatta aaacacaaaa ataatagggg cggtgacaaa
     5521 aaccttgtca ccgtccccta tttcaaataa acggttttct agaataaata gttttcaaaa
     5581 gcttgcatcc gcagtaataa gaacctccca acaaaaatag ctcctcttat ttttatcttg
     5641 gttgaagtta ttacttgatg caaggcagct ttttttactg tgaacattgg ttatatatgt
     5701 ccatgttcaa aaatcatttg gacttcttca atggttttcg catcactgag cgccattact
     5761 tggtcgatgt ctgaacagaa aaaggctaaa tcttggagca ccgctaactg atgttctttt
     5821 tttaaagcca ctacaaataa gagtgtcgcg atttttggtt cctcttttgt tccaaagtcc
     5881 acaccatcag gcacttggac taaatagatt ccttcttcta ctacttcttc atctttgtca
     5941 gtcccatgtg gcaaggctac gaaattcccg atatagacac tcgctttttc ttgtctttcg
     6001 atcattgatt ggatatatgc cggtttgatt cccccttgtt gggtcatcca ctggccgatc
     6061 tcggtcaacg cttctttcca attttgatag gattgatcga gcaatatttt ttctgctggt
     6121 agctgtatca tcttttcacc ttcatttctt tatttcttca atcaggattt tcgctaacaa
     6181 ctgataaacg atttctttat ttcctgagcg gaagatctcg gtgttcaagt cattcatgat
     6241 gattgctcca ctgatctttc ctaaaagaat cccgtctttt tcttggattg gcgaaggcgc
     6301 cagcataact aacatacggg acaaatcgac tggctgtcta tccatccctt caatggtcaa
     6361 cggatgtttc aaattgaaaa tacaaaagat cggtttagaa atcaatgagc tggatgtatg
     6421 gaataacccc atatttgtat gaggaatacc gataggtgct tgttcatatc gcttaagcag
     6481 ccggcgatga accacctctt catccgttac tagtccttca ggaaaataag gaaataagct
     6541 gcgaatcgtt tcggaaatcg tctcaggatt atccagttct tggataaaaa aacgaccgag
     6601 taattgattg atttgatcca tgaaatgcat tgtttcctca taagtatctt ctatcatcca
     6661 ctcgttattg ctgttatacg taattttttg cctttttttc ttctcaatat gcgaaaaagc
     6721 ttcttttagc tgcttgactt catcttctag cagtagcggg gagactaaaa tatattttcc
     6781 accgtatcct ggtaaaatag atgtagaaat aacaacatca tattcttctt gtaaatcgat
     6841 tttttttaaa tcagcaatcc gatagaaatg aatttgttgg atgaagggaa aatacctttt
     6901 caatcgtagt tccaacatgc tagtagaagc taatccactt ggcgaaaatc ctgcaatact
     6961 gatattgctt tctttcggac ttcgttccaa tgaattcgca aaatgaagga ccatataagc
     7021 gatctcttct tcggataatt ttttttcttg aaaaatccgc tctactgctt tacggattgc
     7081 attcgcaact tcctcgtatt gaaccatgat tttttctaaa atcggattgg tcagtgtctc
     7141 ttcttgtaaa acggctcttg aaaacacacc agataaatga gtcaacagca ttttgtacaa
     7201 agtttcatct tcataaaaat ggacattcgt ctcttcactt acttcttgaa tcagttgttt
     7261 tactaaataa gcaagctgtg tatcgaacgt ctcttcaaag aaattctgat caaatgagtt
     7321 cgtgaagtca tttaataatc ctgcaaaaaa gacgatctca tttactggat aaagttgttt
     7381 tgtctcagaa gcgatccgtg aaaacaatcg tttagctgtc tgtagtaatt ctttgtttgc
     7441 cagactatta tatgtctcat ttgtcagtaa atgattttta gtcacacgct ccatcgtcaa
     7501 tgtcagcatc aaaaccaaat gttcaagctt tctatcactt agattggtct ttttttggat
     7561 caattcttcc ccgattactt tgcgtgcaag agatagatgt tgcggatcaa cgaatcgaaa
     7621 aaaataattc agtgatgcat cgaaagaaat actatgaaaa agttcatatt cattgatttc
     7681 taattctaat acattcgctg tcagaagccg gcggtatttt tccggtcctt cgatctcgta
     7741 tccctggttc cgaatgattt ccaaaggcag ttggcgaata ctttcttcca actgtttgat
     7801 atctgcataa aaagtggtat tactgatgcg atatgattcc atgaaatgag caagactcaa
     7861 cggctctgtc gtcagtaaca actcggctaa aatcgcgtgt tgtcgtttag cagtggataa
     7921 gtcattactt ttcccatctg tattttcttt taattgctct aatacttctt ctgatgcctc
     7981 aatgacaaat gagcctctag ctgctttttt caaagaagca tttaccgatt tcaatgagac
     8041 ttcaagatta tctaattcgc ggtaaatagt ccgtttactg accttcaata aattcatcat
     8101 tttttggata gatacaggtg acgggctact gagaaattct gctaataatt gtttttctct
     8161 gggcgataaa tacatcttat atttctccct tcacgagttt ttcgtattca ttcgtagcta
     8221 cccaatgttc aactagaact agccgaggga tcttttcttc tagctgttca gttacagcta
     8281 gttctctttg tgcgatataa atcgtttctt cttggatttt gattttttct attgattctt
     8341 ttgagataac aaactgtttt ttcgcttttt ttgctaattg acttaaaatc gtcatgccca
     8401 tagtttgtga gccgcgtctg ttgtttttat acaaaaatac aatattagca ggcgactttt
     8461 tttgttctgt gatatctgct atctcttttt tttcttcccg ctttggaaat tggatcgctt
     8521 cttttattcg tgacagcaag atatctgttt ccaaaaagtg atccagtaca tagatttgac
     8581 tttgaggtac tttttctctt gcaagacccg ctagttcatg ttgcacgata accagctgat
     8641 ttacttggtt attcaattca tagatagagc tgtatccgac agaaagatcg attttttctg
     8701 ctgctaattt ctttttcagc agggcggctc ccatagcact tgatcccata cctgagtcgc
     8761 aagcaaaaat gacggaatga atgatagatg gttccaagat ttctcccctt tctttgaccg
     8821 ttttgttctc tttttcttta tttggtaatt tcaatagtat cgctgcacaa atgaaggtca
     8881 caaatgtact gattgctatc cctatactta ccccagctag ttgtggataa ggcgcattgg
     8941 caaaaatcac gagtagtgac ccaggcgata caggtgcagc taatcccgta tctaaccatt
     9001 gaaatatcaa cgtgccgctt gccccaccag ccattacagc taaaaataga tacggtcgca
     9061 gcaagacaaa tggaaaatag atttcgtgaa tcccgccaat cgcatggatc atcaatgctc
     9121 cactcgcatt tactttttcc tgtttttctg caaaacaaag gatagaaagt aagatcccta
     9181 aaccaggtcc aggatttgcc tccatcaaaa ataaggaaga gtacccgact gtttgtgaga
     9241 attcgattcc taaaggtgtc aatacaccat gattgattgc attattgaaa aatagtactt
     9301 ttagaggttc taagatcaga ctgacaagtg gtaacagatt cattgtgact agccaagaca
     9361 caacggaggc gagcaacaag tgaacactat ttaaaactgg ttcaataaaa acgattccaa
     9421 ttatacaaat aacgctacca gtcagtccta ctagtaggtt gctgacaagc atttcatatc
     9481 cagccttgaa tttcacgtgg aatctagaaa caaattgttc atatacgatg ccggcaagcg
     9541 gcccgataat catcgctcct acgatttgtg gagcattgga acgagcgatc aaccctaaag
     9601 aagcaattgc accggcgact gccccttttt gtccccctac cgatttcccg cctgaataac
     9661 tgatcaagat gggtaaaagc agctggatca tccaatggca tacctcttct aatgtggtgt
     9721 gcaaatcgcc agacacacct tttgttgcta atgacaagat tccccaagcg ataaacagac
     9781 ttagatttgg catgatcatt tcatttaagt gatgtccagc ttttctcagt tgtttcatag
     9841 acacgcgact gctgttgttt gctttccatt tgtattccat ctttttcacc atacttctat
     9901 ttattgatgg acggatttta tgtagaaaaa gcagcaaacg aaaaaccgtc tgctgctttc
     9961 agctatctgg gaactatttg cctggttcag tcgcaatgat tgctagttca ccttggaccg
    10021 cccactcaga aacgccattt ggaataatac agcttgttcc tttttctaat ggatatgttt
    10081 ttccgtcaac gacaaggtct cctgctcctt cgattaccgt catcaatgta taaggggctt
    10141 gttttttgaa agatgtgatt cctttaatat cccactcata tacattgaaa aactcagttt
    10201 ctaaataagt gacgatcgat gaattccctt ttcggacttc tttgatttgt aattctggtg
    10261 ttttcgcagg gacagttgtt acatcgatcg attgttggat atgcagctct cttgtttgtc
    10321 cttgcgcatc ttttctgtcg tagtcataca cgcggtaagt cgtgtcagaa ctttgctgtg
    10381 tttctaaaat catgattcct ttaccaatag catggatcgt tccgcttggt acataaaaga
    10441 aatcaccttt tttaactggt actttcttca aaaggtcatc ccagcgccca tctttgatca
    10501 tctcagctag ttcttctctt gtctttgcat gatgaccata gatgatttct gcaccaggtt
    10561 cagcatcgat gatataccag cattcagttt ttcctaattc accttcatgt ttcatcccat
    10621 aggcatcatc tggatgtact tgtacagata gatcatcttc tgcgtctaag atcttgatca
    10681 ataatggaaa cactggttct gaaggatggc caaacaattc cttgtgttct gaccatagtt
    10741 catctaatct tttccctttg aattcgccat tttctactac actgacacca tgaggatgcg
    10801 cactgatcgc ccaatcttct ccgattttat cgttagggat atcaaaacca aagactgaac
    10861 gtaaacgact tcctccccaa attttttctt gaaaaactgg ttttaaaaac ataggttcct
    10921 gcataattca aactcctctc atttttcata gctattatag cattatttcg gtaataccgc
    10981 tttctctttc aaaaagtttt caacaatttc atctcgacat atgagatact ccgcacgatg
    11041 atcgacagga tgtacgcgat ttgacaaaaa tatcaacgct tcttgtgttt ttatatcaat
    11101 caagaaaaac gtacctgtat aaccagtatg aaaaagaatc gcatgaccgt cttctacatc
    11161 cttttttaag tcccatccta aagaacgata gccatttttt ttcggtgttt gatcttgcag
    11221 taaagaatca atcgtctctt cttctaaaaa acgaccatta cggatttttc ccttgttcaa
    11281 atacatttgg acaaaagtaa tgctgtcttt caaatcaata aagagacccg cgttacctgc
    11341 atgttcagcc aaaactcttg ctttcggatc atgagtttgt ccacgcaaaa cctcacccga
    11401 aggcagttgt tctgtgggaa cgattttttt ggaaggaaaa ggaagaaata agctgttcat
    11461 cattcctaat ggttccaata cttgttcttg aaagatttcc actgcagttt cttggtaaat
    11521 ttcctctagc atcaacccaa gaagaatcgt accggcatct gtatatttta cttcttttcc
    11581 tagttgctca cctggttcta gcttcaaata agcggcgatc aattcttcct gagatagctt
    11641 atctctgttt ggtatccatg ttttgatatc agaagtatgt gtcagtaaat gacgcaaagt
    11701 gattgtctga ttttcaaatt caggaagata tttatgaagc ggttgatcga gttctatctt
    11761 tccatcttct aatagacgta aaactaatga agtggttgca acgactttcg tcagtgaggc
    11821 tgcatcaaac aacagatctt ctgtcatcag ctgcttttca ggaacgactt gggcaaagcc
    11881 ggctgtaaat gtttctactt gattttcttt tatgaaggcg actgctacac ctggataaaa
    11941 tccttcttcc atctttttca aaataagctg tttcgtgtgt ggatacatct ttttctcctg
    12001 cttttctatc agattcttac agtccaagct taaagcttaa tctatgagga atcaaccttt
    12061 tttacacaaa aaaactgcgc gaaaaaccgc gcagtttccc ccggtatact attttctctt
    12121 tctatctcta gaataagcga tagtatgacc gttcataaaa tgacgagaca tgcgacaatc
    12181 gttaagaaag aaaaagttaa gcgtcgcatc gaatgtcagt tttattcttt tcttttggct
    12241 cactgacgaa ccaccattcg attcctatag catcatagat tgtgagtact gtgtgctttt
    12301 tgtctaagaa gaaatcaact gatagttgct gcaagtgagc aatcagtcct tccatgcttt
    12361 cagtatcgat catgaatttc agaaaatcaa gtccaatcac ttcatctgta ggcaaatcaa
    12421 ttgcgcctcc gctagcttct gtcaaaccaa catggaaatc tccttcattc aatacatgga
    12481 tgccctcttc ttcattatgt accttcaaac caagtacatg attaagaaat tggcgttctt
    12541 ttgttaagtt agtaacattt aaatggattt tttcaaaata agaacctgtt gatagtttac
    12601 tgaatttttc ttcagatttt cttaataatg cttcttgatc cattgtttct ggaatttctc
    12661 tttggtcgtt cttattctct tcatggtaaa tttccaattc attctcttct gggtctacga
    12721 gcaaaatccc catacgtcca tgatcttcta aagcttcttt gattggataa ttcattttac
    12781 ggatacgaca aaggatatct gccatttctt ctgtgctagg gataatcaat gaaaaacggt
    12841 tcagcttttt gatcaccccc atgtgatcat tcgctctagg actttcttcc agcagcaaca
    12901 tttcacttcc agcttcttct gttcctaaaa tggctaattc gttttcttct cttttcaaat
    12961 caaagccaac aacgttcttg taaaaatcaa tcattttatc tcggtctttc acccgaatgg
    13021 ctacactttt taaataggtg gcagccccca attgaaaatc tttcatattt cttgctcccc
    13081 tctacgtcaa gctttatttt aacgatggat tcttcttctt tcaagcaata actttgattt
    13141 tgttaaaaaa aatgtgagaa aattcgcatt ttgcttgttt tttgtaaatt aatgagtaaa
    13201 aactcttata aaaagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    13261 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
    13321 tgaacaccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagatac
    13381 aaaacggaaa aatagcttct catattttgc cgttttttga gctaataccg aaggacagct
    13441 gattgaacac cgtttattcg gaaaaaggga ctgtgacacg acttttgtca cagcccctaa
    13501 aaaaaataat aaatttgtac tattctatga agcttcttct tcagaaaact gactgttata
    13561 aagatctgca tagaatccgt ctttttccat caatgtatcg tggtttcctg tttctacgat
    13621 cgaaccatga ttcatcacaa taatgttgtc tgcatcgcgt attgtagaca agcggtgagc
    13681 aacaacgaaa cttgtccggt tttccaatag gcggttcatc gctttttgaa tcagtatttc
    13741 tgttcgtgta tctacactag atgttgcttc atcaaggatc aggacatctg gatttgctaa
    13801 gaatgcccgc gcaattgtga ttagctgacg ctgcccttgc gaaatattgc ttgcatcctc
    13861 gtttaataca gtgttatatc cttctggcaa tttacgaaca aaatcgtcta cgtgagcagc
    13921 tttagcagcc tcaatgattt gttcgtctgt tgcatcgtcg ttcccatatt tgatattgtc
    13981 atagatactt cctgtaaaca gccaagtatc ttgcagtacc attgaaaact gtgcgcgcaa
    14041 ttcatcacgt gaaagatcac gggtatctac accatcgtaa cgaatactac ctccagaaac
    14101 atcgtagaac cgttcaagaa ggttgatcag tgtcgtcttc cctgcaccag tcggacctac
    14161 aatagcgacc atctcaccag gtttgacatc caagttaaaa tcagtcatta gcaagttatc
    14221 tggtgtgtag ccgaattgaa cattttcaaa acgaactttg tatggtgtat ctttttcttc
    14281 tggaaggcca gatttttcat tggacatctc ttcttcatcc aacacttcaa atacccgttc
    14341 ggctgaagca actgttgatt ggatagtgtt catcaaactt gcaagttgag tgattggttg
    14401 agagaactgt gttgtatatt gcaagaacgc ttgaacatcc cctaatgtca tgttcccatt
    14461 tgcaactttt actccgccta gtacagcgac gaacacatag cctagatttt taacgaaatt
    14521 catcaacggc atgatgattg ccgaaataaa ttgagctttc caaccagcgg catacagatt
    14581 ctgattttct ttttcaaata cttcctggtc tttttcagta tgattgaatg ttttaacaat
    14641 ggtatgacca ccatatgttt cttctacttg gttattcaat aaacctaaac ttttttgctg
    14701 atctgcgaaa aacacttgtg atttcggcgc tacgatcatc acgatgatca agcttaaagg
    14761 gatcatcaat aacgcgacta acgtcaattg ccagctgatt gaaagcatca tcacgatgac
    14821 cccaatcaat gtgactgcac tagttacaaa ttgagtcaaa ttttgctgca gcgtgcttgc
    14881 gatgttatcc atatcattga ttgctcgaga catgatatcc ccatttgtat gtgtatcata
    14941 ataggaaatc ggtacacgat tcattttggc ttccaaatca tgacgtaatt cataaactgt
    15001 tcgttgggaa acacgtgtca taataaattg ctgtaaaaag ttgaatacag cagaaatcaa
    15061 atacatcacg attactgtcg caatgatctg cgcgatttta tcaaagtcta tcggaaattt
    15121 tgttacttgt tggccttgtt gcatctgttg agcgccagcc attacacctt tgaatatttc
    15181 tgtggttgct ttccccaaga cctttggtgt ttggatttgg aagatcacgg ctgctattgc
    15241 tagtacaaat acagcgatga tcgcaaccat acgtttagac atatagccaa acaatcggcg
    15301 taccgttccc cagaaatttt taggcttttc accttttaca ccgagatttc tgccaggtcc
    15361 accatgtcct ggaccgcctg ctggtccatg agagggacgt gtgtttgttt tactcatgct
    15421 aagtcctcct ctcttagttg tgaatgaacg atttcttgat aagtttcgtt tgttgctaat
    15481 agttcttcat gtgttccttt gccaaccagt tttccttcat ctagcacaag gatcatatct
    15541 gcatccatta ctgtacttac tcgttgagca actaaaacgg tgatactttc tttcatattc
    15601 gttttcaatg cttggcgaag attggcatcc gttttgaaat ccaacgctga gaaggaatca
    15661 tcaaacacat agatatctgc tgttttgact aatgcccgtg caattgccag acgctgtctt
    15721 tgtccaccag agaagtttcc tcctccttgt tccacatggc tatctaagcc atcttccatc
    15781 tctgaaacaa aatctttagc ttgtgcgatt tctaatgctt tccaaatcat ttcatctgtt
    15841 gcatccggct taccatactg catattgtct cggatcgttc cagagaacag aactgctttt
    15901 tgaggaacaa agcccattaa ttctcgcaaa ttatattgag tcatgtcact aatgtccgtt
    15961 ccatttattt ggatcgaacc agattcgatg tcatataatc gagggatcaa attgactaag
    16021 gtcgttttac ctgaaccagt cccccctatg attgcgacga tctcgcccga cttggcttgg
    16081 aaatcaatat cttccaatgc aagtttttct gctccatgat atcgataatt gacatgattg
    16141 aaggccaatg ttgcgttttt tccagcaaaa gaaactgttt taggattttc agggtcatgg
    16201 ataccgattt tttcatccaa cacttcatta atacggtcag ctgaagcttg tgcacgaggc
    16261 accatgataa aaatagcgga aagcatcata aagctgatca agatctgcat cgcataagtc
    16321 ataaatgcaa tcagattacc gacttccaaa gtcatatctg ctatgtagtg tccaccaaac
    16381 caagtgattg ctacgtttgt accgctcatg atcaatgtca tcattggcat catcaatgcg
    16441 acgatcgtat taactttgat tgccgtattt gtataatctt tattcgctaa atcaaaacga
    16501 ttttcttcaa agcgtgtctt atcgaatgct cgaatcactc tgacccctgt caatccttct
    16561 cgaaatacca ggtttaaacg gtcagttttc ttttgcatac ttttgaataa tggaacagca
    16621 aagtacatga ttccgccgat caaaataatc attactggga tgacaactaa gaagattttt
    16681 gtcaactgat gatctttttg ataagcaagt atgctcgcgc caatcaacgt gattggtgca
    16741 ttgatcatca tacgtaaaaa catttgtgta accatttgga tttgagtcac atcattggtc
    16801 gttcttgtga tcaaagaggc cgttccatat ttatcaaacg catcttttgt cagactctct
    16861 gattttttat agacatccgt acgcaattgc ttacccagtt tctgtgattc acgagtagca
    16921 aaaaatgtat ttgcgatagc agctaagata ctgatcaaag aaaagccgat catcacaaaa
    16981 cctgtatgcc aaatataatc gacatctcct tgcgctaccc ctttatcaat aatattggag
    17041 gtaagtgtcg gcaaatataa atctgccagt acttggatca ccatgaaaac tgcagctgca
    17101 attgctgaag tcaaggagat ccgttttacg atttttagca tctagttccc ttctttctat
    17161 ttatatactc cgtttttcag ccaagaaagt ttcaaattga attcactgat tgcttgctct
    17221 actgagtaat cttcagatgt tgaaaataag cgatacgaat gcgcaattgt tgtaaataca
    17281 gtattcatca ctaattggat cagtaattcc aattcatgat cattttttac tttcagcttc
    17341 gtccgatcga tcaattcaag caactctttt gcatcttgtt tgtgttcttt atgtggatcg
    17401 tgaggcgttt tttggcgact cgtatgagga gcgacttttc ttgaggcacg gtaatccatg
    17461 ttcataaaca agttacgata aaaagaagca ttctcgcctt ccaaaatctc ataaatcatt
    17521 ttagaaaaat aggattcgaa tcctttgaat agatcaccat cggattcttt cattagttgt
    17581 aacatatctt tagagctgtc acgtctcatt gtctcaaagt aataaaaata aagatcctct
    17641 ttatcttcaa aatactgata gaaactgcct ctagggatat ccgctaattt gacgatatta
    17701 gcaatcgaag cttcttttaa gggtactcta gaaaactcga ttctcgcagc ctcgattagt
    17761 cttttttgtt tttctttagg caaatggaaa aatgtctgtg tcggcatatg gatcctcctt
    17821 tctttcaaga tgacacattg tcatatgacg ctgtgtcatt ataacacctc ctacctgttt
    17881 tgcaagacat ttgcatagtt tttttcatta tcatccgata cattaaaaaa gtgataagag
    17941 gaatccttcc atttgaatta atgagagttg cccattaaaa tagccacata ctaaacaaag
    18001 gatgagataa atggcccaat caattagtgt ccaagacttc aataaattgc ctctcgatgc
    18061 tgacagcatc gttttagata caagaaatac cttagattac acaaaaaacc acttaagcca
    18121 ctcgctttct atccccgctg ctatcttgcc aagacaatta aaaaatctag atccaaagaa
    18181 actttaatat attctaagct atacaggcag gcgatcagaa gcattagccg atcaacttac
    18241 tgctaatggt tttcgtgctg tttatatcat tggtgggatg gaagctcttc agtcgagtgt
    18301 tgcttgaata ttgcttgtta gattcaaaag aggctgtgac aaaaaatcgt gtcacagcct
    18361 cttttatacc ctgtcttttt ttagttattt attcttcaac cttatcaata tgacttgata
    18421 gccttttctt tttctcatag ttataacaat catagcaata aaaggagaag gtaagcatat
    18481 ggcatctgtt ttagtagtca aaggtcatcc cctaactgca gaagaatcgc gcacagttaa
    18541 ggcattgacg tcttttttaa caagttataa agaaaatcat ccagatgatg aagtgactgt
    18601 tttggaactt tatcgcgatg atattccgga aatcgatgaa gaattattat caggttggga
    18661 agcattacgt gctggtgcag aattcacttc cttatcagaa agtcaacaac aaaaaattgc
    18721 tcgtttcaat gaattgactg atcagttcct tgctgctgat aaaatcgtta tcgcaaacgc
    18781 cttatggaat ctaaatatcc caacaaaatt aaaagcttgg ttcgataccg tcaatgtagc
    18841 tggaaaaacg ttccgctata cagaaaacgg gccagaagga ttagtgacag gtaaaaaagc
    18901 actgcacatc caatctaatg gcggtgtata caacggacaa gactttgcct ctcaatatgt
    18961 aaaaggtatt ttaaactttg taggcatcga tcaagtagat cagctattca tcgaaggaat
    19021 cgattatgac cctgaccgtg cagatgagtt gatgcaaaat gcattagata aagctgctgc
    19081 tttaggtaaa tcattttaaa aattgagata aatgcataca aaagagacag aggaaaaaat
    19141 cttcaaagca gcatttgtac cttggatatt ttcccatctg tctctttttg ttattctttc
    19201 tgctttttca acggattttc ttcataaaga gaagagattg ttgtgtacca ttcaaaaaca
    19261 tgagtaatca ctactttagc tgctgcataa acaggaatcc ccaagatcac accgatgatt
    19321 ccgaacaatt tcccagaagt cagcagaact aataaaatcg ttactggatg gattgctaac
    19381 tgattcccta gtactaatgg agagatcaag cgtccttcta ttgtctgctc tactgcaaaa
    19441 acgatcagta ctttgatgat catgaatgga cctgctacaa tggctaaaaa gatagccgga
    19501 atcatcgcta aaaatgatcc taagtaaggg atcaggttca aaaaacccgc aataatcccc
    19561 aacgtgacag catactctaa accaatgacc gcaaaaccaa tcataaacat gattgccaca
    19621 gcaaaagcca cagttagttg tcctcttata taagaagaaa cttgactatt catttcactc
    19681 agcacattca acgtcggttt ttgcatgcgt gtcggtaaaa atttgacaaa ataaggtgct
    19741 aattgtttac cgtctttcaa tagataaaat aagataaacg gcatcgtcag cagagccact
    19801 aaaatagtcg ctaccgcgcc gacaaaactt ccaagactct gaactgtact cttagatata
    19861 tcttggatca tatcgcctgc cgaattcatg aacttatcac ctgctgtttc caactgttcg
    19921 cgaaattggt tgaacagcgg gtcccgcaaa atctcggtta atttattatc aatcgtatct
    19981 acatattgag ggaagttact gatgaagctc actgtttgtt cctgaatctt agggatgatc
    20041 actacgctcc cccatgcgat tagtgcaaca accaaaacaa acagcccaat gatactgtaa
    20101 agccttggta cttttcgctt ttcaaagtaa tcaactaccg gattcatcaa gtaatacaag
    20161 attcctgcta aaatgatagg cagacctacg attgctaaaa attgccagat tggtgcaaac
    20221 aaatatgaaa cttttgtaaa taaaaagacg atcagcaata ttaacaatac aacaagtaag
    20281 gctgtgacta cttgattatt taaaaaccag cgccaaaacc acgataccgg tctgttcttc
    20341 ttattttttc cttccataat tcctcctgtt agttataaaa aatttggctt cccaaaccaa
    20401 tagcaggcag tctatgcgga tgaagataga ttccatttgc aatttgtcct tcttctggac
    20461 aagcatcaaa aatcaatgat acgtgagcta ctgtctctaa attcccattg gccatcggac
    20521 cgacataatc gatcgtatat acctgatcat caaaagcaat tgttccgcct gctttcaaag
    20581 aaaaaggttc gtcttttgat acttcttgaa tcaccgaata ttttcgtaag gcagctgttg
    20641 ctgttttatc gaacaaaatc agcatgggtt cttccttgtt tattgcttct gtcccaattt
    20701 ctgtaatctt tgcctgaatc attgcactct ctcctttaat tgctttcaaa aacagtataa
    20761 cacattctca ttctttagcc gtgtggaata attatgtgat agaataaaaa cgaaaactat
    20821 ttcattacaa ttaggaggaa tcagctcata tgatcgaaaa gataatttta ggaacctata
    20881 cgcgtcgcga aagtaaagga atctatacga tcgaccttga tacagaaaaa gaagaattag
    20941 ccaacctttc attagctgtt gaagaaaata gccctaccta tgtagcaaaa agtaaagctg
    21001 gcaatcttta cacagttact agtgtggatg gattaggtgg tgccggtgcg tacgataagg
    21061 attttcattt tttgaatgcg gtaacagagt ctggcgctcc tttgtgttat gtagcggttg
    21121 atgaagcacg tcaattacta tacggggcga actatcataa aggtgaagta aatgtctacc
    21181 atatattagg agatggcgaa ctgaaagcag cagattcaat attccatcaa gaagcgacag
    21241 gtcctcataa aaaccaagat catgcgcatg tccactatac ggatctgact cctgaccaac
    21301 gattagtcgt atgtgatctt ggtacagatc gtgtgtatac ttatgatgtg tccgaaaacg
    21361 gcaaattgaa tcttgtaact accttcactg cagagccagg aacaggccct cgccatcttg
    21421 tctttcatcc aaatggacaa ttcgcttatt tatttggtga attagacagc acagtccgcg
    21481 tgctttctta taataaagaa acaggtgctt ttgaagaatt acagaaaata tcgaccttgc
    21541 cagaagaatt cgacggtgaa aatggagggg cagctatccg catttcaaat gatggcaagt
    21601 tcctttatgc ttctaaccga ggacataact cgattgctgt attcgcagtt tttgaagatg
    21661 gttcccacat tcaaaacaag caaatcatct caacagaagg ggattttccc cgcgatttcg
    21721 cactagatcc aagcaataat tttgtcgtgt gtgccaatca gaacaccgat aatctgacat
    21781 tatatcgccg tcatcctgaa acaggattac tggaattact gaaaaaagat gtctatgtac
    21841 cagaatgtgt ctgtgtttat tttgatcgtt agtaagaaaa ggagaatgaa atgaatcagc
    21901 aagacgtatt agacagacta cgggaagaac taaatattcc tttctttgat gggaaaatcg
    21961 aagataaaga gtatagcgaa gaggaatatc agaaactcaa agccgattta cagaactact
    22021 ttgaacaata tgtacagaat gtagaaaact aatcagcttt ccatactatc tgaaaagaac
    22081 atcaggacaa gacttttccg tctatcctga tgttcttttc tacaaataaa aaaccgccga
    22141 gatggttaga ctcgacggaa aaggagtatt tactcgattt tgagtaagta caaggttgtt
    22201 gttggttata ggtatgtcat tatcataaag gattttgatc actctatcat aaaggtaata
    22261 ttacatttat attagataac tctagttttt attgttatca aagatttctt ttattttttc
    22321 aacaacaaat tagtcatttt ttggatggca gctgtcaatt ggtctgtcgc ttggtcttgt
    22381 tttgcttcag atgtattgaa tagatcttca tctacccctg attcaagatc gatactttgg
    22441 atcatttctt cacagcctgc tacatatgaa agataagctt tttcaaaatt tttatgaatg
    22501 cccattgctt ttgctggtgg acgcaaagta ctgactttct taagcattgc ccgatatttt
    22561 tttgttcctt cttcaaataa caggatgatc tcttcaagag tcgatttgtc cagttcactt
    22621 gtttttcctt catcaattgc gtttctgatc acttcatatt tcggatgcat tccttctccg
    22681 attgcttctg tttccttgac gatttgatcg atggactgca cataatagcc aatattcggt
    22741 aacatgttcg ttttcctact ttctccattg ttgttattat ttattctact tgtttttatc
    22801 ctcaaatgac aagtacttga aaaaatttaa tggtttctat acagctcgcc attcttattc
    22861 gtgctcaaag aaaccatctg ctaaactata ttgtttccct gcgacaatgt catattggat
    22921 caattgatat tcgtcgtaaa tctcttgttg cgagcgattg aattgcgctt ctttatacca
    22981 ctgtccgttt tgatagtaca gttctcgttc aaacgccgga agttcctgtt ctaatgataa
    23041 aagcagctga taaaagccat ttgttgtctg attcgtctgt tccattagat tcgctgcaaa
    23101 ataaaacgga ctggtgattg catcgtgagt cgtttgcttt tctaattctc ctttactgtc
    23161 gaacataaga aattgtgttt catgcaatgt ttgtttgtca ttttttgctt ggatcgtatc
    23221 tgaatagatc cctggaagat gatcccccca aaaaacaact aaagtccttc tagaaagatt
    23281 cttcaattct tccgtgaact gcttcagtgc cgtgctgcta taggaaatat cttgcagata
    23341 attctctaag tcaagtgtcc cacttccatc tgaagttttt gcaggatagt ctagattatc
    23401 atactttcca tcgtagggca tatgtgtctg catcgtgact aaatgaatga actgaggtgt
    23461 tttttcttcc ttgagaagtg tcattacttc tttgtaagct gactcatcag aaatatatgg
    23521 attattctct atcgtatccg tataggtcat cgtacgctcg ctgatgaact ggtcaaatcc
    23581 taatgtctga taaacatcct ctcttttata catcgaagta ttgtatggat ggatcgctgt
    23641 cgtctggtat gattgtgcgt ttaacgctga aacgatagaa ggaagctgat ccatttttgg
    23701 tacaagcatc gtgtaagggg tggtgagttg cgcattaaat aacgccatag aaaaaccagt
    23761 caatgcttca aattcgatat ttgctgttcc accgccatag ttttgagaaa gcatattgcc
    23821 actatatgtt tgatcagcta cttcataata atctgccaat ggctcaccag atacttctac
    23881 gccgtttaat cgactaggat ctgagaaact ttcactcatc acgaacacga tgttcggcga
    23941 ctcttcctct acagttttat ttttttcatc ggctagcttc tggtattttt cagtgatttc
    24001 tttgatcttt tctttcgaat atccttcagg ttcatccatt ggttctacct tcagattgta
    24061 caaaaaccca ccgataaaac cagtgttata gtagttcatt ttctggctgt aaggtatcca
    24121 tagtgccgtt ttattatatg cttttcgcaa caaattatcg ggattgttga aattactgat
    24181 ataccctagc agtccaattg ccacaagcag tgtcgttaat cggatcaatt ggaatcgcct
    24241 tccttttttc aggcttcgaa acatgtacca gcaaaacaat cctatcacgg ttcctgcggc
    24301 agctaagatc actgtaaaca gcatagtgcc ggtcatatct ttcagcaatc cgatttcagt
    24361 gatcatcttc aaatcgtctg gataaatcgg ttcttgccga taactcattt tcatataatt
    24421 tgcaaaacct aatacaccga tggctacgac atacgtaagg gaacctaaag ggacagatcc
    24481 tgctagtgca atcagaaaaa taagaataat cagcaagacg agacaggcta agaagaattt
    24541 ttccgtatgc caagaaaaag caaatttcaa cgcaaggtct acggatagat cattttgaca
    24601 ccactgcaaa aataaattac taaaaacaac aagaaaaaag atactgatga ttgctgctgt
    24661 tccttttaaa atctttttct gtttggtcga aagtctgctt atatatcttt tcaaatgctt
    24721 gctccttcat ttctatcaat aaaagaatgt tgcttctctt attttagttg tacgaaattc
    24781 gaaagtaaag aacggaaaga agaattaatg aaatccaaat attctctttc tttatggcct
    24841 ttctggtttc tttaataagc ggacctttcg tactccagaa attttttcta gctgttgttt
    24901 cacttgattg agctgttcaa aatcagtact gtctatgtca atcaatatgt agacatgctc
    24961 attcttatgg ttacgcgata tatctgcgat cgctagctcg ttctcattca gcagagaaaa
    25021 tatctctgct aatatattgg ttttcttttg ataaaatata gtgaatcgaa acggcgcttg
    25081 gaaaaacatt cgtgcggatg gataattgac cgcttctcta accgtaccga acaaaagata
    25141 atcttttaag gcttcaactg ccaaacgtcc gctgtctgcc aaagcttcct gagtcgatcc
    25201 ccctagatga ggcaacataa gtatacggtc attttctaag aactcttctt ctggaaaatc
    25261 agtcaagtat ttagccagat gttgtttttc caatgcttgc ataacagcat atttatcaac
    25321 aatttcactt cttcctacat tgataagtac agcatctttt ttcatttttt ctatattcgc
    25381 ctgatcgatc aatccttttg tatcttctgt caacggcagc atgactacga tgtaatccga
    25441 ggtagaaaga actgtttcta aatctgcttg ccgaacataa tccaactggg catcgcggat
    25501 agaataaccc aagacatcca tccctaagct atagcaactt agcgctactt ttgtgcctat
    25561 cgctccaaga ccaagaagac cgatggtttt gccttgcaat tctcgtccca cataagcact
    25621 tcttttgttt tctgcctgtt ctaaaatatt aggacctgtt agtgtttgta ccatacgact
    25681 tgcttcgatt atcggacggg aagataagag caaacagcac aaaacaagct cttttactgc
    25741 attagcattt acacctggtg tattcatgac gatcgtcccg ttttcagaag ctttttcaac
    25801 gttgatcgtg ttcaccccaa caccagctct tgaaattgct agcaaatctg gtgtaagcca
    25861 ttcatctttc actttcgtac tacgaataac tattccttcg gctggcaaat catctattat
    25921 tttgaaatat tccccttgta acttttctat ctcttgttct ggaatagcat caatcaaatg
    25981 aacgtgatac ataaaacccc ctccttacta acaagtatct cgaaatttct gcaattagac
    26041 aactgtttac catttgactt cctagaagca aaaagagcag ttagagcaga gtaggctgag
    26101 tgataaaaat aaggctatga caagttactg ccataagcct tattttcgag agcaaaatat
    26161 tgagggtgag atatcttgat aaatggtgtt ccgttagctg acattgataa taagactaaa
    26221 tttcaaaaaa gttgaaaagc aaatttcgtc aatctcttct tatttcttaa aactaagtgg
    26281 ctttttcaca acctcttttt atctaataac cactgtttcc aactcaacta attttgccca
    26341 cgtttcaatt tgatctgttg ttagatttag cgagacaacg gtatgatgac cgccacctgc
    26401 ctgaatccat gaatggacac cttcatggaa attcggttta gttttccata acacacgtgc
    26461 aacaggtaaa ttaggtgctt cagtcgttgg ttcaaaggct tctacttcat tgatcagcag
    26521 tttataatgc gtaccgaaat ctgccatcga tacgactacc ccttctcctg ctttcccatc
    26581 aaatacaaga cgcgccggat cttctctatc tcccattgat aaaggagaaa caacgattct
    26641 tggtttcgtc gcagcaagcg tcggatctac ttccatcata tgggattcca agattgcttc
    26701 ttggccacta gctagctcgt aagtataatc ttccatgaat cctgtatctt tccctcgagc
    26761 catgattttc agcaaccgat caatcgctgc agttttccag tcgccttccc cagcaaaacc
    26821 gtatccttct gccatcaaac gttgtacagc tagtccaggt agttgtttca ttccatacag
    26881 gtcttcaaaa ttagtcgtaa aagcgttata gcctccttct tctaagaaac ggcgaatacc
    26941 gatttcctgc tgagcttgta cttttacatg ttcctcccat gtcttttctt cataatcacc
    27001 atagtcgaag gtatacaatt ccttgtactc ttcaaataat tgatcgactt cttcgtctga
    27061 tacgcgatcg attacttgta caagatctcc gataccaaaa taatcaacag tccaaccaaa
    27121 ttgaatctgt gcttccactt tgtctccttc tgtgacaccc acgtttctca tgttgtcacc
    27181 aaaacgagcc acttttattc caaaactttc attataggct actgcaacat ccatccaatc
    27241 agcaatctct ttttggatct caggtcgttt ccagtagcca acgacgattt tattttgttt
    27301 atttaatcga gcattgatga acccatattc gcggtcacca tgagcggatt gatttaaatt
    27361 catgaaatcc atatcgatcg ttttccaagg aatgctttcg ttatattgcg tagctaaatg
    27421 aagcaatggt ttttgtagaa gctttgtccc gcggatccac atttttgctg gtgagaaagt
    27481 atgcatccaa gtgatcacac ctgctacttc ttctcgataa ttgacctctt tcatgatttt
    27541 tgtgatcgta tcagcagtaa ctgctaattc ttgaaggcgg attggataag gcaattggcc
    27601 attttcattc agttcatcga ccatttcttg tgcatgtttc tttacttctc gcagtgcttc
    27661 ttccccatat aaatgctgtg atcctacaac aaaccaaaat tctttttctc caatattcaa
    27721 cataattagc cactcctttt atttgttttg tccgtaatac gcattttttc cgtgttttcg
    27781 taaataatgt ttatctaaaa tccgttgagg cagctcttct gaaaatgaat tgagctgtct
    27841 ggtaaataaa ttcatcttgc atacttcatc tagtacgact gcgttcatta ccgcactttg
    27901 cgcatctttc ccccaagtaa atggaccgtg tccgtgtaaa agtacccctg gaattgctaa
    27961 gggatcaatt ttgcgttctt tgaatgtttc tatgataact tttcctgttt catattcgta
    28021 cccgctgtcg atttcctgtt gtgtcaaaaa tcgagcacaa ggtaccgatc cataaaaagt
    28081 atctgcatgc gtcgtcccca tcgcaggaac atccaatcct gcttgtgccc agatcgtcgc
    28141 ccatgtcgag tgagtatgga cgattcctcc gatttgagga aatgaacgat ataaaacagc
    28201 atgagtaggc gtatccgaag agggattgag tttaccttca atgatatgat tgtccaagtc
    28261 cacaacgacc atgtcgtctg ctgtcatctc ttcataactg actccgctag gtttgataac
    28321 gaaatatcgt gtttcaggat caaaagcgct cacatttccc catgtatatt tgacgagtcc
    28381 gtgtttaggc aagtcaagat ttgcttggta tacttcttct ttcagttgtt ccagcatttt
    28441 ctatcactcc tttttcttgc aattgatgaa tcgctgtttt ttcaatgtcg atcccctcac
    28501 ggtaacgtct cataaatatc tgatagcctg ctatttcttc tgctgaaggt gtgatggtga
    28561 ttccttggtc ttgtccaaac acgtcttctg ccaagaagtt ttctaaagac ttcccatgtc
    28621 gatccatcat ataggctgct aataacgcga ttccccacgc tccaccttct ccggctgtgt
    28681 ccatcactgt aactggtgcc tccatagcag atgctagaat ccgctgtcca acttctggtg
    28741 ttttaaaaat ccccccatgc cccactaaac gatcaatttg gacattctca gatttcaata
    28801 tatccattcc gattctcatt gcaccaaaag cactggctaa atggatccgc atgaaattcg
    28861 ctaaatcaaa acggctacct ggtgtacgta caaataatgg ccttccttca tttactcctg
    28921 taatgttttc accggaaaaa taaccataag aaagtaatcc cccgcaatcc gtatcgcctt
    28981 ctagcgcttt gttgaataat accgtgaata atttatctct gcttatctcc atacccaaag
    29041 aattggtaaa ttcttcaaaa atactgaccc aagcattgat atccgaagag cagttattcg
    29101 tatgaaccat gcctactagt tctcctgaag gtgtagtgac catgtcgatt tccggatgga
    29161 cattttctag ttctttttct aatacgatca tagcgaaggc ggaagtacca gccgaaatgt
    29221 tccctgtccg tttggctaca ctgttcgtag cgaccatacc ggttcctgca tccccttctg
    29281 gcggacaaac cgggattcct ggtctcaaat ttcccgtagg gtcgatcaga taagcccctg
    29341 attcgcttaa cttgccagct tcttctcctg ctactagaac tttaggcaaa atgtgatcca
    29401 agtcaatcgc tacgtgcgct ttttcgatta actgaccaaa aatatttttc atttcttgat
    29461 ggtaggtttt cgttgaagga tcgataggaa acatgcctga tgcatctcct acgcctagta
    29521 ctttctcacc agtaagctgc caatggacat aacctgcaag cgttgtcaaa aaattaattt
    29581 ctttcacatg ttcttcttta ttcaaaatag attgatacaa atgagcgata ctccatctct
    29641 gcggaatatt gtattgaaat ttttccgtta atattcgttc tgcttcttca gtgattgtat
    29701 ttcgccaagt acgaaatggt actagtaact gttccttgct atcaaatgct agataaccgt
    29761 gcatcattgc actgaaccca atcgacccga ttgtcgtaag attctcgcca tagatttcga
    29821 atacttctgc tgccattttt cggtaactga cgcgcagtcc tttccaaata tcttctaatg
    29881 aataggtcca gataccattt tctagtttgt tttcccactc ataactacca gcggcaatag
    29941 gagtaaaaga tgaatcaatc aatacagctt tgatcctagt tgatccaaac tcaatcccta
    30001 aagatgtacg accatctatg acatctaaca tactttgcgc atttacttcc ttcataatga
    30061 tttaactccc tccttctcgt caaacctgat caaaccgtct ttttagtagc gcttacaatg
    30121 attattgtat acttttgtac gtacatgtca agcggttatt tacaagaata caataaaaaa
    30181 cacttgtttt gtacgtacat aagttataaa atgaaattgc ttacaaaatc tgatcaaccg
    30241 ccttctcgaa attctagaag gagagaatac ttatgaaaaa agaaaaaaaa gtttcctcat
    30301 cgtttattta tttttttggc gcatttggcg gcattctatt tggatatgat attggtgtta
    30361 tgaccggcgc cttacctttt ttacagcatg attggggttt ggcaggtaaa gcttctttga
    30421 taggatggat cacgtcttcg gtcatgttag gtgcgatcct tggcggctct ttatctggtc
    30481 ttctttctga taagcttgga cgacgaaaaa tgattcttct ttctgcactt atttttatgg
    30541 ctggttctgt cctttctgca tctgcccctc acaatggttc ttattttctg attgcagcaa
    30601 ggattcttct aggtttagct gttggcgctg catctgccct agttcctgct tatatgtctg
    30661 aaatggctcc tgctagacta aggggaagat tgtcagggat caatcaagtg atgattgctt
    30721 ctggcatgct cctttcctat gttgcagatt atttgctaaa agtgttgcct gaaacgatgg
    30781 cttggcgcgt gatgttaggg ctcgctgctg tccccgcgct gattttattt ttcggtgttt
    30841 tagctctacc agagtcaccg cgttttctta tgcaatctgg ccgcttggaa gaggcaaaaa
    30901 gagtattgaa ctatattcgg acaccaaaag aagctgaaca ggaattcgaa caaatccagc
    30961 tgaatgtcaa acaagaaaag acaaccggaa cttcttggca tactttgttt ttagaaaaat
    31021 atcgttcctt agtcattgcc ggtattggtg tagcagtatt ccagcaattt caaggagcta
    31081 atgctatttt ttactatatt ccgctgatcg tagaaaaagc gactgggcat gcagcgagcg
    31141 atgcattgat gtggccgatc atccaaggaa tcattttagt tgctggttct ttgctctttt
    31201 tggttattgc agacaagttc aatcggcgaa ctttattgaa aataggcggt agcgtgatgg
    31261 gactttcatt catcctacca gctgttttag gaactgtact ggatgctcat acaaattcgt
    31321 tgttgattct cttgttttta tgtatttatg tcgcatttta ttcttgcaca tgggctccac
    31381 tgacatgggt aatcataggc gaaatattcc cactagctgt ccgcgggcga gcatctggcc
    31441 tagcctcttc ttttaattgg attggttctt tcctagttgg cttgcttttt cctgtgatga
    31501 ctgcttctat gtctcaagaa atcgttttcg gcatttttgg gatcatctgc tttttagggg
    31561 ttttatttat tcaagagatc gtaccagaaa ctcgtgggaa atctttagag gaaatcgaac
    31621 aaagtgcatc taaaaaaact tatcctaaac gtatttctat ccatcattct taaagaggtt
    31681 gtgacagaag tggtcagctt caagaaataa gaaggaaccg cttagtttcc agtcacaagg
    31741 aacaatttca aaaaacagct tctcatgttt gatgaatatt gtgacttgtg accagttggt
    31801 aggagaacac cgtttagtgg agaggtggtg aaagaaacgt tcagccttga gcgatgacaa
    31861 aagctctcac aaacattgcg acgagtaacc gtaggagcaa taagaggcgg taaaaacccg
    31921 tctcttattt ttcgttttct ttcactgttt cccgttcaac tagtacaggt tcatagagaa
    31981 tatttggctg tgcctgtcct ttttcaatcg ttgtgacgat ccaccgtgcg gcatcttgtc
    32041 ccaacttttc ttttggatgc gtcaatgttg tcaatttttt attccctaaa tggcttaaag
    32101 aagaatcgtc tgttcctacg atcgataggt catctggaat atgatagcca ttttctgtca
    32161 acttatctag cattaaacta gctatttgat cgttatagca aatgatgcca tctaaagctt
    32221 gttcttcttt caaccgttgt actgtttttt cagcgattgt ttctcgtgtt tccgtggtga
    32281 aagtaatgat atcttccgtc aaaaaacgca cattatactg ttcacacgcg ctgataaaac
    32341 ctttcatcct gtattttcct tgaagatcgt cgatttttgt gatgaacaac agacgctgat
    32401 gtcctttttt tatcaaatat tctgctgcca taaaaccgac tttcacatca tctaaacaaa
    32461 tataagaggc atttaactct tcataagcag cattgatcat caccatcgga atgccttgtt
    32521 ctctcaaagc aacataaagt gctaagtttg ggttatactg attacttttc gtaggctcaa
    32581 cgatcaaacc atctacccca taagcaatca ttttcttcaa acactctttc tccaattcgt
    32641 gatcgttatt cgtactggct aaaagcaatg aatacccaga ttctcgtaat tcattttcga
    32701 ttcctcggat aatcgacgga aaaatataat cagagagata tgtggtgatg acaccgatcg
    32761 tttttgttct gttcaatggt gttttttctt tcttatagct gtcatctaca tatgtgcccg
    32821 accctttttc tttacgcaga tagccctcat ttaccaacac agcgattgct tgccgaatcg
    32881 tatgtctgct gacgtcatat atttcttgca gcttgaattc tgagggaatg gttgtattta
    32941 cttcgtattc ctcacgaagg atcttttgtt ttatctcttc tgcaatatct tgatattttg
    33001 ccatttgcct tgcccctttt tatttgtacg tacatatatc ataacgagtc tgcaaggttt
    33061 attcaagcaa aaatcaaggt ttcttgtgct cataaggcat acggaacagg ttcaccaaat
    33121 tctggaaatc cttgctcatt ccacgtaaag cattgcgcgt tcgcgtgccg attaggattg
    33181 tctaacggat cccctttttg gttcttctct ggtcgagcat gatagatcaa aatatcaaag
    33241 cacccgtctt ctgaaaccgt aaacgagttg tgaccaggac caaattgctt atttttttca
    33301 gaagaaacga atactggctc cgataattta tgccatgatt cttttaataa aagattcttg
    33361 tgctcatcag cccacagcag gcccatggca tagttttcat ctgttgcact accagaatac
    33421 gtaatgaata ttttcccatt gcgagtaagg actgctggac cttcatttac tgaaaaaccc
    33481 cgtttttccc attcatactc aggtatagaa aggaggatct gcttcccctt taacgtccaa
    33541 ggattatcca tttcggatag ataaagatta gaattcccag taatttcagg atcttgttgg
    33601 gcccacacat aatatagctt tccttgagaa gagaaagttg ttccgtctaa actgaaagtt
    33661 tcccttttcg tttttatttg tcccttttct atccaatctg tattcattgg atctatatgc
    33721 tgattttcaa gtacgaacat gcggtgatga tgagattcat cacgtatagt tttatgattg
    33781 cttgcagcaa agtaaatata ccattttcca ttgatataat ggacttcagg tgcccagatc
    33841 aattcactca tcggtccttc ttcatgagcc tgccatacaa tcaggcttgc agcatgttct
    33901 aattcattca gtgactttgc ccttcttaat tcaatcactt ggtagcctgg aaccgatcct
    33961 gtaaaataat aataaccatc tgtatgttta tatacccaag gatctgcccg ttgccgaacg
    34021 ataggattat tataaagtgt cttcatcata acaaatttcc tcacattttc tttattctaa
    34081 ttacattcca agagtatttt tctatcccta catttaattc gtcatgtttt tctattgaaa
    34141 aatagtttat ttcaggtttt attttttctg gttcttcacg tgtatttttg tccaacagat
    34201 cgctactggt taatgtgtag tgctctcctt gatctagcaa attgaaatca tgttcaatcg
    34261 ttatcttttg ttgttcattt gtgcgattga tcaagaaaat agtcagctga ttgccgttat
    34321 ctacgatcac actgtccaca taaggaacat tttttatctt ttcacaatca taaacagggc
    34381 aaatgatttg ttgtttcaat acttgacctt tagcatatct cgataagtgt tgcatcacat
    34441 aataagttgg attcctccat gcttgtcctt tagcatctgt cagtattaaa ggtattgtgt
    34501 ttactaacaa tgattgacaa ctaatcttta cgcgatctgc gtgtcgtaaa atagccagcc
    34561 ctaatgaacc aaataataat gtatcttcca tagtaaagta acaccaatcg atgggactac
    34621 cgacttcaaa atccctatgt cttttttccg gttgggcatg tacattccat tcatcaaacg
    34681 ctagatacat tgttttctca cttctcaaat atccttttac ataatcacaa gtagcaacga
    34741 tttcttcaat ttgacgatcg aatcgataag cttttgcaag gtatgtcgct gtatcatcac
    34801 gctcattttt aggaggttta gtcaagtctt cttcatcata cttatcaata tagttatgca
    34861 aagctaaata atctacattc tcataagctt cttctaatgc gatacgatcc cattcagggt
    34921 acgatggtaa acgtggcgta gagcttccaa ctaagattgt ttcaattgaa tcatccacta
    34981 acttcatgac ttttgaggct tcatttgcta acctaccata ttcataagca ctcttagccc
    35041 ccacttgcca tggaccgtct agctcattcc ctaaacacca taatttaacg ccaaaaggct
    35101 ttttttgccc attttttatt cttaaatcac tccagaaggt tccttttgga aaattacaat
    35161 attctactaa attttttgct tcatcaattc cttttgttcc taaattcacc gtgaatatcg
    35221 gtttcgcttg tacatgactg atccatttaa aaaattcgtg gagtccaaaa gaatttggtt
    35281 ctatacctcg ccatgctaaa tcaatttttt ttggtcgttg ttctttccta cctacagtat
    35341 ccacccaatc ataaccagat gtaaagtttc ctccaggata gcgaatgaca cctaattcta
    35401 attcctttac ataagagagg acatcttgtc taaaccggtc accatcagct gtttcatggc
    35461 ccggttcata aatccctgta tagacgacac ttcccatatg ctcaacaaat gagccaaaca
    35521 gccgagaact gatctctcct accgtaaaat cctctctgat ttttactttc acttcttcgt
    35581 ccaacagctt tccctacctt tcatttccta tagtcaagat aatagataca agtttccata
    35641 cgccaccagc aaagataaaa ataaaaggag ggaaaagaaa tatgagcagt acaaatccta
    35701 ataacaatac gcaacaaaga atatttctca aaaaatcaaa aaatactttc catgcacttt
    35761 gttcaaaaat ttgtaaaaat gtgatatctt tgttttcaga aatcacatat atccaggata
    35821 aaagaaacat ggaataaata agtaaaacta catatccact aattgaaagt acgattgtct
    35881 gttcttctaa taattgatta acaagaaaat aaataatgat cgttaacaga ctaaggaaca
    35941 agttcttacc aaaatgttgc tttattcctt gaaagaaaaa ataaatgata tttcctgatc
    36001 cctcaccttt ccattgcgcc attacataaa aaacagcaca tgtagcaggc acgatagtaa
    36061 taacaggcaa acacacgatt acccagagaa tacctaataa gatgtaatca gaaaccacaa
    36121 tcaactgtcc ataaaattta gtctcaacta ttttcatctt cctcactctt tcattccaga
    36181 catagctgtt ccttgaacaa aatatttctg tgcaaaaata taaaccacta gtaatggcag
    36241 cattgaaata accgttccag ccattacagg tccataaaaa gaaatgttct gccctgtaaa
    36301 taaagctaac cctgctggta aagttctcat ttttgaacta cttgtcaata tcaatggata
    36361 aagcaagtca ttccaactat tcatcagcgt gaaaatccct aatgataaaa gagtaggttt
    36421 gctcaatggc aacatgattt tcaaaaaaat attaaactca cttaatccat caatgcgtgc
    36481 tgcctcttcc aaagaatctg gtaaagtaat aaaaaaggaa cgcatcatga agataccaaa
    36541 tgcagttgtc atacgaggaa tgatcaaacc tgcataagta tcaagcatgc caagcaaatt
    36601 gacttcaata aatagaggaa tcatgaagac ttggaatggg atcatcattg tcagcaaaac
    36661 gaaatagaac aaaactgatt ttcctttgaa acgcatacga gcaaatgcat accccgcaag
    36721 agaatcaaag aatacagaag tgatcactgt ccctccagca aaaatcactg tatttttgat
    36781 gtaatctaat aaagggatcg ttgtccaaac cttaatatag ttatctaggg tatagctatc
    36841 tgcaaatatt ctaggcggaa atgagataat gtctttttcg tgtttaaaag aagaaataat
    36901 cagccacaaa aaaggaaacg caataaccaa caatataact agcatactaa tcgttcgaat
    36961 gattttttta ccactaactg cttttcgact attcacagta actgtaatcg agctttctgg
    37021 tgccatacag gtttccctcc tatttcattt gtttttcttt ccgtgacatg tacacattag
    37081 tggagatagc tatagttgca acaatgataa acaaaaccga agacagtgct gatgcatagc
    37141 ccaattcata aggtgctgta aatcctcgac tgtaaatata ttgaacagct gtttctgtct
    37201 taaattgtgg gccaccagcg gttgcaacat atacttggtc aaacacttgc atcgaaccaa
    37261 tcagattcgt taaaatacaa aaacctaagg agggaacgat ctgaggtagc gtaatgttaa
    37321 aaaactgctg tcgatttgtt gcaccatcca tttgagcaga ttcatacaaa gagggagaga
    37381 ttccctgaat agcagtcaag agaatcgtca tagtaacacc aaaattcttc caaacagtca
    37441 tgatggctac cgtcggcata gcaagggttg gatcgcgaaa aaattgaggg atcggcaagc
    37501 cgacttgtga aaacaagtaa ggaatcgccc ctacattcgg atcaagcaac atagaaaaaa
    37561 taatcgcaat tgacgtcaat gaacaaataa ctggaatgta aaatgtcgaa cgacaaaaac
    37621 gattgaatct ggtattttta gataatgcta ctgctgctaa taaaccaacg ataatttgtg
    37681 ttggcgtttc gagtacggtg aaatataaag aatgaatcaa cgaattaact gctcgttcat
    37741 cactaaatat acgtgtgaaa ttttcaaaac ttacaaaatt tcttgatgta aagaaaatat
    37801 tcaaatctgt aaaactaata gcaaatgttc ctaaaagcgg tatgacagta aataataata
    37861 aaactaaaaa agatggagtt aaaaacaaat acgcagcacg atcaggacga ttccaatatt
    37921 tggtgaatcc gttcatatag tccacctcat ctttcatttt gataaaatat acaatcttgg
    37981 tttaaacgaa tctgaataag atatccgaac aatcgctgtg atttttgcaa taacacctat
    38041 ctgcaaatac taggtcgatc attcagatat ctgtatcttg ccaacagtct atcctgtata
    38101 aagttctgta ctatttttgc agtaattgat tgatggcatc atctgcatcg ttcatgagtg
    38161 tctcaggatc ttctcctgct aataattttt caatcagtgg attgatgata tcgttattga
    38221 tcgcagagat ttgggtaaaa cctggtaaat atggctctgc atagtccatt tgtttcgata
    38281 attcagatac aataggatca ttttttactt cttcatcttt tgctactgaa tccaagtagg
    38341 caggaaaacc attttcgata ctccattttt taccaatttc agttgtattc caatatttca
    38401 aaaactcata gacagcttct tttttattat tatctgtact tgccggaatg gcatatccta
    38461 cgccatctaa aatagctgtt tttttgtctg aatcactccc ttgtggtaag gtagtcacat
    38521 tataatcaat ctcgtttgct ttcaatccgt tatttaacca tggcccattg atttcaatgg
    38581 ctagttgacc agcattcatt aaattgtcca tttcggcgcc agaaatcgat tctggaccag
    38641 tcttgtctac atggatcatt ttttggatcg cttttaacgt tttaaggttc tcaggagacg
    38701 caaattcaga cttagtataa tcatcgttca ctaatttacc gccatttgct aacatccagt
    38761 tatataacgg tgcagttcca tccttattga agacaaaacc tgatacattt ttactactat
    38821 cagttaattt tggtgccatt tctgtcaatt cttcccaagt agtaggtggt tgttcagtat
    38881 ctaatccagc ttgtttaaac aaatcattat tccaatacat atacatgcct tgtacctgca
    38941 tggggacaaa atactgttta ccttctactt cacctaattc aatagccgtt tctttaaaat
    39001 cagatttatc tactccatca tattcccaga aatcgtctaa tggttgtacc gctccgtttt
    39061 ctacatactg tgcaaaatct ggataattta atgcaataaa gtcaggtgct tttttagaag
    39121 aaatcgctgt aggaagtttt tcattcaaat tggcccaagt catgatatcc atttcaattt
    39181 tgatgttttt atcatttgtt ttattaaatt cattaacgat ttcttgcaat atttcaccat
    39241 cagatgcagt aaacccattc caaaaagtca aagtcacttc tttatcagaa tcagattctg
    39301 ctgaacttcc gccaccgcaa gctcctaaaa tacctgttgc agctaccaac aaagagccaa
    39361 ttaaccattt tttacctttc attttttgtt cctccttcat ctgataaacg acatctgacc
    39421 acattccaag atagcggttt caataaacaa ttgattttcc catcttcagc ttttacattt
    39481 gttgaatgac ttggttttac ttgttcactt ttaggaagat tagttgcttt tgtatcaaat
    39541 ccactcattt cagaaaaatc aatcactccc tctaatgata attcagacaa gtgaacagtt
    39601 agattcattt cttcttctcc acggttaact gcaaatatga caagttcttt gtcatttatt
    39661 acggctatac tttctaaata cggcacttct tcaaaatctt ccgtcgcata gtttgctgaa
    39721 cgaatttgtg ggcttaacac ctctccttgt ccatacacag cagcttgcat aaatggataa
    39781 tagatcgtct gtctccaagc ttctccgttt gtttctgtcc tgattggtgc aataacattt
    39841 accaattgag caagacaagc aatctttact ctatctgcat gtttcaataa agtgattaat
    39901 agacagccta atagtaatgc atcttcaaaa ttatagttat cttctagtaa aggaggagca
    39961 atctgccaag gcgctgcttg ctcatcttgt tccgctgaat gataccaaat attccattca
    40021 tcaaaggaca ggttgatctg cttcttacta tgtttcttcg ccttgactgt atcgcacatc
    40081 gctgtcactt cagaaatgaa ccgatccatg tctaaggaac gtgcaagata atgagaaaga
    40141 tcattttttt ggttgccata atattgatgc agagacaaat aatctatttg atcgtacgct
    40201 tgatcaagaa ctgttaactc ccaatcacca aatgtaggca tttgccgatt cgaacttccg
    40261 cataaaacca cctcaattga atcatctacg agtttcatcg ccttagccgt ttcctctgct
    40321 aaccgtccat attcttccgc tgttttatgt ccaatctgcc aaggaccgtc catttcattc
    40381 cctaaacacc atgtcttaat tccaaaaggg ctctcttgac cattcgaacg ccttaaatca
    40441 ctccaataag ttcctttagg aaaattacaa tattcgacta aattacgagc tgcatctact
    40501 ccacgagtac ccagattgac agccatattg atttcggccc ccacatgctg acaccagtta
    40561 taaaattcat gaatcccaac ttcattcgtt tcaattgtcc gccaagctaa atccaacctt
    40621 ctaggtctat ttgctatggg cccaatactg tcttcccaac gaaatcctga cacaaaattt
    40681 ccaccaggat atctaatcat gggaatgttc aattctttta ccaagtgaat gacgtcttgg
    40741 cgaaatccac ttttattagc tgatggatga tctggctgat aaatcccttc atatactgct
    40801 cgtcccatat gttcaataaa tgaactgtac aaccgcggat caactttgcc tacacgcttg
    40861 acactactaa tcaacattgt ggcttccata actgacctcc tttaatttat acatgaataa
    40921 tacacctcgt tgaaagcgtt gtcaataata taaatgttaa acttacttat tttttatcga
    40981 ttttaattaa ccaaaatatt aataatgatt aaaacaaata atttaatata acttttatta
    41041 acaaatatgt taatatataa gaaaaacctt ttaagaggtg atatatatgc aactacaaat
    41101 aaacgaagaa tccttaccgg tatatgaagc attagctagt aaaacaagga tcaagatcat
    41161 ccagctactt tccaaaaaaa agatgaatgt caaagatttg gcaaaagaac ttggagtgag
    41221 cagtgctatc acgacgatgc acgtgaaaaa gctagaggaa gcaaacatca tcaaaacaga
    41281 aaaagtagga caacaaaaaa tttcgagcct tcgtgtcgat aaaatcgata tcagttttcc
    41341 agaaaaaata ttcaatgctt ttgatacgaa agaaacatcg atacctattg gtcactatac
    41401 aaattatgca attgaaccaa catgcggttt agctacgatc catgatttta tcgggaaagt
    41461 ggatgaacca cgctatttta tggatcctcg aaggatggat gcccgcattc tctggtttac
    41521 cagcggattt gtcgagtatc aggcacctaa ttttttaaat acagaggata cattggagat
    41581 gttggaagtt tctgtggaaa tttcttctga atttcctttt tcaaatgaca attggccttc
    41641 agatatcact ttcagcctaa atggtgtgga gctaggaaca tggacgagcc ctggagattt
    41701 tgctgatatc cgcggtaaat atacgcctga ttggtatcca gataatctta atcaatacgg
    41761 cttgctgaag acgatccgaa ttaccaaaca cttgacgaat atgaatggag aacccttgtc
    41821 aaacatcacg atcaacgaca tccctaaaga gcaagacact tggcatttgc gaatcgaagt
    41881 gaaagacgat gccaaacatg tggggggctg tactttattt ggtaaaggat tcggtaatta
    41941 cgatcaggat atcaaattaa aagtttacta cagctgatat ttttcttttc tattttataa
    42001 aacaaaaaca gccaatccct atgaagggac ggctgttttt gctttattgt tatttccaga
    42061 aatcatccaa aacggaaatt ggcaaatgtc gtttatgttg tgtcttgttc caccatgctt
    42121 cgattttttc ttgtgcttga gcgggaactt cttttccttc tagataatca tcaatttcat
    42181 tatatgtgac acctagtgcg acttcatctg caatcattgg tttcccatct tcaagatctg
    42241 cagtcggaat ttttgtgtat aatttttccg gtgcattcaa tgcttgaagc aattgtttcc
    42301 cttgtcgttt gtccaaacgg aataatggca aaatgtcggc tccaccatca ccaaatttcg
    42361 tgaagaatcc agtaatgttt tctgcagcat gatctgtccc taatacggct cctgctcttt
    42421 ctccagctac ggcatattgc gtaatcatac gttgacgtgc tttgatattt cctttgttaa
    42481 aatcgctgat tcccacacct gcttcgctta atacttgtac ttgtgcatca acagctggtt
    42541 tgatatttac tcgcagacta acatcgggct ggataaagtc aagagcagct tttgcatctt
    42601 cttcatctgc ttgttcacca taaggaagac gaacagcgat aaattgatag ttttcatctt
    42661 ttgtttcttc acgcatttct tccatcgtta gttgcgccaa acggcctgct aaagtagaat
    42721 cttggccgcc gctgatacct agtacaaaag ttttaagaaa cggatatttt ttcaaatatg
    42781 ctttcataaa gtcaatactt ttacgtattt cttcttttgg atcaattgtt ggtttgacac
    42841 ctaattcatt gataatttct gtctgcaggc tcatttattc tcctcctatg cttctgtatg
    42901 aagttctgct acgctttttt tcattcgttc catgatagcc attttatggt tccagcattc
    42961 agtagacaga tcgactgggt atttttgcgg attcaagtct cgtttatact cttcccatag
    43021 tgaatctaga ttttcttttg tatattcttt gatttcgttt agtgcaggta attcgtaaac
    43081 tctttttcct tcgataaaga tatcttgtaa aactgggcga gctgtaaagt ctcgaacagt
    43141 tttattgata aacgtatgca ctggatggaa catgaagata gcttcttctt ctcgagggtc
    43201 ttcatcccat aatgtcacgt agtctccttc agatttccca tcaaaatttc gagtgatgcg
    43261 ccacacttgt tttttccctg gagtagttac tttttctgca ttgcttgata acttgatcgt
    43321 atccatcatt tttccttcat catcttcgat cgatactagc ttgaatactg caccaagggc
    43381 tggctgatca taggctgtga tcaattttgt cccaacaccc catacatcaa ttttagcttt
    43441 ttgcatcttt aaattcaaaa tcgttgcttc atccaagtca ttcgaagcat agatttttgc
    43501 ttccgtaaat ccggctgcat ctaattgttc ccgaacacgc ttagatatat aggccatatc
    43561 tccactgtcg atgcgtacgc cttggaagtt gattttgtca cctaattctt tcgccacgcg
    43621 aatcgcactt ggcacacctg atttcaacgt atcataagtg tcgactaaga acacgcagtc
    43681 tttatgggtt ttagcgtagg ccataaatgc ttcataatca tttccataag attggactaa
    43741 cgaatgagca tgggtcccgc tagctggtat cccaaatatc ttcccagcac gtacattgct
    43801 tgttgcatct gctccgccga tatatgccgc tctagttccc cagactgctg catccagttc
    43861 ttgtgcccgt ctagttccaa attccaatag tggatcttct ccgatgacag atttgatacg
    43921 agctgctttt gtcgcgatca acgtttggaa attgaccata ttcaacagtg ctgtttctac
    43981 taattggcag tgcgctaaag gcccttccac ttggattaat ggttcatttg caaaaactag
    44041 ttctccttca cgagcagaac gaactgttgc tttaaattca aaattttgta aatactccaa
    44101 aaaaccttca ggatagactt ctaatccacg caagtaagca atatcggaat cattgaacgt
    44161 cagattctct aaataattga ctaaccgttc caatcctgca aaaaccgcgt atccgtggtt
    44221 aaaaggcatt tctcgaaagt aacattcaaa aacagcatgt aaatcagctc gacctaattc
    44281 ccagtatgtc tgcatcatat tgatttgata tagatccgta tgcagcgtca aactgtcgtc
    44341 tgggtaagta ttattcatct tgtattactc ctcttggcaa gttttcattt cctacccatt
    44401 ataacaaaaa aaattaatag gaaaagaaat cttccatttt ttctgaaaaa gcacatgttt
    44461 tacggatatt tcttgctaaa aatgaactcc atctgctaaa actatccttt cttattggta
    44521 tttaacctaa acgagaaaga atacttattt tattcaatgt atccgagaca cgaagaaatt
    44581 agcgttttct atttttctta cttgataaaa taagtagatt ttcctactac aatcgtagcc
    44641 gttaagatac cgatgattga acaaatataa ccaaatgtct ctacaacata atcaatggca
    44701 aaagtttttg aagcaataat acgtctttcc ttttttgctt cttatcccca aagaaacgga
    44761 tataacttat tatgtattga atttttttgg aaaggcgaat tatgacaaga tataccttgc
    44821 gttgaaaaaa ctcgcggaaa aaatatcaca cgtttttaaa aagatacaaa gtaagaaagc
    44881 agctgtcaat agaatggaaa caaaaatggc gagacatcaa tcagtctcgc cttgtttttt
    44941 attgtataca ttagatatgg agcaggttac cataaagatg attattagtc gttattaaat
    45001 agaatccttc gtattttttt gttctatcac tacaatatct ttatttggac gtttgaattg
    45061 tattccggca cgttctagct cctgtttcac tcctacatgg actttgacat cttctcgtgt
    45121 catttttaaa acgtgatgaa tcgcatagtc gatttcttgc cttgtgattt ttttcttcgt
    45181 attgatcatc acgacttgct ttttatcata tgtgtctacc aatagcagtt gtgttcgatc
    45241 taacgaaaat aatttgtaat aattaatagc cgtattccca aaaaagaatt ccactacttt
    45301 aggataaaat gtcttaatat ttaaattact attcacaggt gtttcgatta gcttcatctc
    45361 attcctcttt tctatatagt cgatttagat ccaatcttaa gttatgttac catctttcct
    45421 agcattaagg aatcggttac aattgaacct ttaaagacaa aaggatttac cttttatcac
    45481 ttaatagtat aacataattt cgtgagaaaa aaatacaatt ttttcttgac catctcgtta
    45541 cgtaaaggat tatgcttaca tttgtcagga ggaaaaataa tggagtacac aataaagaaa
    45601 atgtcagaga tatcaggagt cagtccgaga accttgcgct tttatgatga gattggactg
    45661 ctaaaaccag ctaggatcaa ttcttcaggt tatcggattt atggcaaaaa agaagtcgat
    45721 cgtctgcaac acatcttatt ttatcgaaca atggcattca agttggatga tatccaagag
    45781 gtcttagaca atccatcttt tgaccaccag aaagctttaa tcaagcatca gcaaatgttg
    45841 ctggaaaaac gggcacaaat cgataccctc ttgacaactg tccaacagac acttgatatg
    45901 tacgaaggag gaagaaaaat gagtgacaaa gaaaaatttg aagggtttaa acaacaaaag
    45961 ttgaaagaaa atgaagaatc ctatggacaa gagattcgac aaaaatacgg aaaaaaaaag
    46021 gttacagcat ccaatgaaaa atggatgaat atggataaag aaacgtatga agaaatgcaa
    46081 actgttgaaa agcagatgtt atttgatctc actctttact taaaagaacc agaagatgaa
    46141 agcttagcag accgtatctt ccaagctcat aagaagtggt tctcttacag ctggcctgaa
    46201 tatcagccaa aagcgcataa aggactagga atgatgtacg aagccgatga acggttcact
    46261 gcatattatg acgagcgaag tggtcatggt gcagcaaaag ctttaaatga aattatccaa
    46321 aaaaaggcgt aatcttttac atgatccaac aaaaaagtac acgtaaaatg acctaataac
    46381 aaaacagcag acacccaagt tagattttta tgctaacttt tggtgtctgc tccattcttt
    46441 cacaagtttt ttcatcctac tttaaatata ttcatcgttg aataaacgta taaggtattt
    46501 tcactttatc ctttttttct gtaagaaaca attgaaatgc catttctccg caagcttcca
    46561 gatggtggtc gatggttggg aaaccaagaa gctcgctgat cagcaaatta tcgcgtccaa
    46621 tcaccactgg tgtcttatct tgcagatagc tttgcaagat gcctgctgca accatatccg
    46681 aatttgtaaa gacaccatca actccaagct ctttaaaaaa gaagcctgct tgttttcctt
    46741 tctctgcatc tatacaatcc caaaaaacaa gtgattcatc aaaagatgga aaaagttgat
    46801 gacatagctg caaagtgatt tttgagttat aacttagcct gccacttcgc cccaacgtga
    46861 tgcccaattg ctttatacct tgctgcttca aataagtaag accttctgta attgattgtt
    46921 ctcgatcaat aaagacacag cttgcctgtt ttcccttgat ttcttcacaa aaaactagag
    46981 gtccatattt ttgatatgcc aataaatcat ctagtgtatt ggcacgagac gtaatgatca
    47041 atccatcgaa agctttagct gcaaattctt caagatacct tcgctctttt tctttatgat
    47101 agcccgtcgg taaaagtgtc actttgtaat cataatcaaa cgctgcttca atgatcccac
    47161 tgatcaactg atcaaaatac ggatgattgg tataaggcag aatcactcca atgcttttcg
    47221 tttttccata acttaactgt ctggcatttg cattagggat ataatcgact tctttcatga
    47281 ccgcaagtat ttctttcctt ttttcctcat ctacatatgg atgtccattg attacacgtg
    47341 aaatagtaga aactgaataa cctgtgagct ttgcgatatc tcgaatgttt gccactgctg
    47401 cttcgccacc tatacaaaaa gattttcttg taaatagtct accacagctg gaccgcattc
    47461 aaaaaactga tacatttttc cttcatgcga aaaactgatc cgctgcccgc cccaatatat
    47521 atcttttgtc aaattttcga tttcattcat tggtatttct tttactatat tcctattcaa
    47581 cccttgaaaa ctgtacaacg ttaatacgga tcccttgaac tcgacaaacg cataaaaata
    47641 attgttcgtt gtgccatctg ttatctctac ataagtattc attgcaagcc ctccttttga
    47701 tactttgagt atagtgtatg aaacgcgtct catagcaagg agtttgtttt gccaaagaaa
    47761 agttttattc ctctttcatt attaccaaag tctcttattt taaattgaat acattataat
    47821 gatactgtaa atatatcttt attattagtg aatg
//
LOCUS       DAFEEZ010000014        46959 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000014
VERSION     DAFEEZ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.014"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(253..2019)
                     /locus_tag="LP245_000903"
     CDS             complement(253..2019)
                     /locus_tag="LP245_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518838.1"
                     /translation="MQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVTMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(1979..3733)
                     /locus_tag="LP245_000904"
     CDS             complement(1979..3733)
                     /locus_tag="LP245_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518839.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(3843..4412)
                     /locus_tag="LP245_000905"
     CDS             complement(3843..4412)
                     /locus_tag="LP245_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBL1518840.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(4430..5845)
                     /locus_tag="LP245_000906"
     CDS             complement(4430..5845)
                     /locus_tag="LP245_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL1518841.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(5856..6524)
                     /locus_tag="LP245_000907"
     CDS             complement(5856..6524)
                     /locus_tag="LP245_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBL1518842.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(6655..7239)
                     /locus_tag="LP245_000908"
     CDS             complement(6655..7239)
                     /locus_tag="LP245_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1518843.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(7570..7803)
                     /locus_tag="LP245_000909"
     CDS             complement(7570..7803)
                     /locus_tag="LP245_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBL1518844.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(7818..8765)
                     /locus_tag="LP245_000910"
     CDS             complement(7818..8765)
                     /locus_tag="LP245_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBL1518845.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(8765..9607)
                     /locus_tag="LP245_000911"
     CDS             complement(8765..9607)
                     /locus_tag="LP245_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL1518846.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            9929..11116
                     /locus_tag="LP245_000912"
     CDS             9929..11116
                     /locus_tag="LP245_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL1518847.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
     gene            complement(11208..11948)
                     /locus_tag="LP245_000913"
     CDS             complement(11208..11948)
                     /locus_tag="LP245_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL1518848.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGETNYIESSKN"
     gene            12636..12794
                     /locus_tag="LP245_000914"
     CDS             12636..12794
                     /locus_tag="LP245_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1518849.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
     gene            12866..14086
                     /locus_tag="LP245_000915"
     CDS             12866..14086
                     /locus_tag="LP245_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1518850.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKTVFEAFQKGLKN"
     gene            complement(14179..14571)
                     /gene="rpsI"
                     /locus_tag="LP245_000916"
     CDS             complement(14179..14571)
                     /gene="rpsI"
                     /locus_tag="LP245_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBL1518851.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(14587..15030)
                     /gene="rplM"
                     /locus_tag="LP245_000917"
     CDS             complement(14587..15030)
                     /gene="rplM"
                     /locus_tag="LP245_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBL1518852.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(15549..16016)
                     /locus_tag="LP245_000918"
     CDS             complement(15549..16016)
                     /locus_tag="LP245_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBL1518853.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(16136..17674)
                     /locus_tag="LP245_000919"
     CDS             complement(16136..17674)
                     /locus_tag="LP245_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBL1518854.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            17754..18440
                     /locus_tag="LP245_000920"
     CDS             17754..18440
                     /locus_tag="LP245_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBL1518855.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(18641..19168)
                     /gene="msrA"
                     /locus_tag="LP245_000921"
     CDS             complement(18641..19168)
                     /gene="msrA"
                     /locus_tag="LP245_000921"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL1518856.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(19252..19929)
                     /gene="pgmB"
                     /locus_tag="LP245_000922"
     CDS             complement(19252..19929)
                     /gene="pgmB"
                     /locus_tag="LP245_000922"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBL1518857.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(19926..21056)
                     /locus_tag="LP245_000923"
     CDS             complement(19926..21056)
                     /locus_tag="LP245_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL1518858.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(21056..23239)
                     /locus_tag="LP245_000924"
     CDS             complement(21056..23239)
                     /locus_tag="LP245_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBL1518859.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIAPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(23236..24261)
                     /locus_tag="LP245_000925"
     CDS             complement(23236..24261)
                     /locus_tag="LP245_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1518860.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(24306..25133)
                     /locus_tag="LP245_000926"
     CDS             complement(24306..25133)
                     /locus_tag="LP245_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL1518861.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(25130..26197)
                     /locus_tag="LP245_000927"
     CDS             complement(25130..26197)
                     /locus_tag="LP245_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBL1518862.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(26223..27059)
                     /locus_tag="LP245_000928"
     CDS             complement(26223..27059)
                     /locus_tag="LP245_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1518863.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(27056..27925)
                     /locus_tag="LP245_000929"
     CDS             complement(27056..27925)
                     /locus_tag="LP245_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1518864.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(27995..29278)
                     /locus_tag="LP245_000930"
     CDS             complement(27995..29278)
                     /locus_tag="LP245_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBL1518865.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(29292..30977)
                     /locus_tag="LP245_000931"
     CDS             complement(29292..30977)
                     /locus_tag="LP245_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBL1518866.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            31252..32276
                     /locus_tag="LP245_000932"
                     /pseudo
     CDS             31252..32276
                     /locus_tag="LP245_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
     gene            complement(32871..36545)
                     /gene="rpoC"
                     /locus_tag="LP245_000933"
     CDS             complement(32871..36545)
                     /gene="rpoC"
                     /locus_tag="LP245_000933"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBL1518867.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(36603..40220)
                     /gene="rpoB"
                     /locus_tag="LP245_000934"
     CDS             complement(36603..40220)
                     /gene="rpoB"
                     /locus_tag="LP245_000934"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBL1518868.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            40948..41916
                     /locus_tag="LP245_000935"
     CDS             40948..41916
                     /locus_tag="LP245_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1518869.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            41934..42839
                     /locus_tag="LP245_000936"
     CDS             41934..42839
                     /locus_tag="LP245_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518870.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            42836..43642
                     /locus_tag="LP245_000937"
     CDS             42836..43642
                     /locus_tag="LP245_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1518871.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            43778..44767
                     /locus_tag="LP245_000938"
     CDS             43778..44767
                     /locus_tag="LP245_000938"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBL1518872.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(45084..45608)
                     /locus_tag="LP245_000939"
     CDS             complement(45084..45608)
                     /locus_tag="LP245_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBL1518873.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            45895..>46959
                     /gene="scm"
                     /locus_tag="LP245_000940"
     CDS             45895..>46959
                     /gene="scm"
                     /locus_tag="LP245_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBL1518874.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        14006 a         9601 c         8192 g        15160 t
ORIGIN      
        1 ctctacttaa aacggcaata tgaaagaaac tataactttt tattcaatct tttatgttta
       61 actggtttat cgccaatttt ttaaaacttt gattattcct tatattataa gaatagacat
      121 taagtgaact aattcaatca tactgattct ttcgtgtatt caaaattaga tgctgtttaa
      181 taaaattatt ctttttgaaa aagaattata actatatccc aaaaattgta ggttaattta
      241 aagcctattt catcatcgtg attgagcttc tttttcatag acgaatttct cagatagttt
      301 agttttcttt atgagatttt tgtatatttc tgaccttcga tacaactcat tatgagtacc
      361 ttgatcaact agttttcctt gatccatcac tacaatttta tttacctttt caatagactt
      421 caagcgatgc gatataatta gtactgtctt atcttgtatt aaacgattta aactttcctg
      481 aatacgtttt tcattttccg catctaaact ggcagtaatt tcatctaaaa ttaaaattgg
      541 cgcatttttc aaaaaagccc gtgctatgga taggcgttgt cgctctcctc cagaaagtga
      601 acttccgttt tctccgacca atgtatgata accgtcaggt agtttttcaa taaagtcttc
      661 gcagttagct aaacgagctg cttttttcac ttcctcatct gacgcttgac tatttccaat
      721 acgtatattt tccaaaatac ttgtattaaa caaagttacc tcttgaaaaa caatagcgat
      781 tttgctaaac aaagaagctg gagatacacg tttaatatca tacccatcaa ttaaaataca
      841 gccttcatca taatcataca gtctagacac taatttcaag atactagttt tcccggaacc
      901 actagcacct actaacgcag tcacttctcc ttgtttagcc gtaaaagaga tatgatctaa
      961 aattggggta ttgttatcat atgagaaaga gacatctcgc aactcaatgt caaaagattt
     1021 cagaggacta tctgatccct cttggatact ggtttccttc atagctctaa ttcgctgtat
     1081 tttaggagct aaataaaata tttcaagcac tgcttctttc atagaatcga aggaatcctt
     1141 tatttttatt gcggctagta agtaaccaac gacgtagagt atagtcactt cacccgttaa
     1201 cagtaagtga acacctacta gaatgactac tgctaaacta acatatgaga aaatagagga
     1261 taaggccatg actgaaaaag tacttaattc tacctttaaa tgaatccttt cactctcttc
     1321 catttttttg aaaagtctgt cttgaacttt tttagataga ttaaagctat taatctcttg
     1381 ctgcaattca atagtttctt gaaattcttc cgagttttct ctcaaagtat cgtaatattt
     1441 agtattggct ttcgtttggg atttctttga taacaagatt aagacaaaac taaataacgt
     1501 tggcaaaata acagctaatc ccattgtgac attaccaacc aaaagcatca ctgaaataaa
     1561 agggaaaaac agagccatac cgccggcttt aggtattgca tgactcatcg catgctcaat
     1621 accttcaacg tcagacatga tagtttgaga taaatctgat aaattatgtt ttgaaaaata
     1681 ggataatggt aaatttgaca aatcgtctgc aatttgcact cttaaatgcg cactttcttt
     1741 ataagtacta ttatataagt tttcatactc cctatctaac aaccaataca tgaaaagcaa
     1801 agtaacaaac gatactgcaa aataaagcca acggggcttt gcattttcta aaactaattc
     1861 gtctatcagc atcattataa tgaatgctgg taccatatta atgcagtata caaaaaaact
     1921 agaaatagaa gctttagtta aagcttctgc gccctgatca gttaaagcaa attttttttt
     1981 ataaaaattt ttcattgtca agcctccaat catttgcatt ctcataatta gtgaccaatt
     2041 gtttatacac tcgatgttta gccattaatt cattatgatt tccacgttct actatttttc
     2101 cttctgacaa gacaagaatt tcatctacag atttaatgct ggataatcga tgagctatca
     2161 taataactgt tttttctttc atcaaatatt gaaaagcctt ttgtagttca tactcattat
     2221 ctggatcaat agatgcactg gcttcatcca taataacaat ctttgcatct tttaaaattg
     2281 ctctggcaat agctatacgt tgtttttctc ctcctgacag ataaactcct ttactaccaa
     2341 ttaaggtatg ctctctttcg ggaaattttt ctaaaatcga ttcgcaaccg gctaatctta
     2401 gcgcgtcaaa tactttactt gctggcgctt gaggatttgc tatagaaacg ttatcgtaaa
     2461 tactctgatt gaatagtttc gtatcttgaa agacaaaagc aattgtgtta ataattgtgt
     2521 cttttgaata gtgatttaaa ggcttaccac caattttaat ctgtccctta tccacattgt
     2581 agaaacctga aattagttta gctatcgtac tctttccgct tcctgatttt cctactaatg
     2641 cataaattct tttttgttct aaaactaagt tgaaattttc taaaacacac tcttctttgt
     2701 atgaaaagct gacattttca aatgcaatgt cacaattttt aatctgtgtc tcgttcccat
     2761 attttagttg gtcttgcttc atttctaaat aaagggagtc tagtgtttcg actgcatatc
     2821 ttgcttcaaa caagtgcata cttacataca ttattctcat gaaagaaaca aaaataattc
     2881 cacttaaaaa aaacaacatc aacaagtcaa cagctaatat cttgggagtg gtaagagaag
     2941 ttataaaaaa ggttatagga actatcaaaa tgcaaactat gccaaaaaat agccattgaa
     3001 aaagaacaaa aggtgttttc ccactcaaag aatacttata tgcaaactta gcataatcgt
     3061 taattgcttt attcaaggct ttaaatgatg ttactttagc accaaatatc tttataactt
     3121 gaattccgcg gatatattct accgtttcag agcttaacac atctaacgat tcttgatatt
     3181 tttgaataaa atttgtattc tctgtcattt tctttaacaa gaatacacca attactaaca
     3241 tggcgattag aaccaatcca attttaaagt taatgaaaaa gcctaaggca actgataaaa
     3301 caggtgttac tatggcttga gcactatctg gaatcaagtg agcaattgcc atatgtgttt
     3361 tagccgcgtt gtcatcaatt gtctttcgaa tatatcccga agaatttaaa tcaaaaaaac
     3421 gaaaacttgc ttctgttaaa ccgctaattc ccttttttct caaattagtc tctaagcgaa
     3481 acccaaggat atgagaaaat aagccagaaa aaatataaaa taaagctcct aaagttaacc
     3541 aagcaacagt ttgaaccgca taactcttag ctaaatattc atctcctaca ataattagag
     3601 actgaagaaa tttgtaaata ctgtaatatc catagactgt taatacgaca gaaaaatcag
     3661 aaaataaagt ggctaaccat ccgtagtatt tcattttagg gacataacta aataattttt
     3721 tgtatacttt cattttttcc tcccccgcat tcaatttctt ctcttattcg tttacaactg
     3781 ttaatgcttt ccgtaatagc gtaaattaga gatgtacaaa cagatagaag gtaaactacg
     3841 ttctattttt tgtatttttt taagactttt cttccaatca atacaccaat catagataaa
     3901 cttgctacaa ctaacactga aataattccc catataccca ccgcgtagtg gatcattgca
     3961 tccattgttg cagcagattg tcctctatct atccagtctt gacgaaaacg atctgtaaag
     4021 aaccatatgg gaatccactg tccggcagca ctgcctagtt gcattagaac ccaagacaca
     4081 acttgaggaa ttgctcgatc atatccaaat acagatagaa taatatcagc taagatcgcc
     4141 atactaatcg aactgataaa ccaaggtaag tacgccccgc ccattaacgt aaaaaataac
     4201 aataaaacaa ttgtgtaaat agtaaaaatt ccttttctag ggtagttata gctaatataa
     4261 acaaatatga ttccagataa taatccaaaa atccctgggg atatgctgtg accaaacgcc
     4321 ccaccaatac tactaaccat tattgaaaaa aagtaaatta ctagggaaat aactgtagct
     4381 aaaccaataa aaatataatc ttttgttttc atatatattc tcctcaattc tatttcgtta
     4441 tgtcattaaa aatctgttct atcaaagttg aatcttctac tctaagtttt atatcttttt
     4501 ttattccacc attttttaaa taaataattc tattgcatgt tttataaaga aattccggat
     4561 catgagtggc tataactact gcaccctttt cttttaagtc tttaataagg tcagcaatcc
     4621 tttccatatt gatataatcc aacccacttg taggttcatc aaatagaaat aaattagttt
     4681 ttgacaatga agctatagaa accaataatc tttgtttttc tccaccggat aaatcaaacg
     4741 gtaattgatc tttcatttta taaagttcca ttttttttaa aattttttct tgctgatctt
     4801 tactaactat ttcattcccc agggctaact cgctcctcac tgattctgtg aaaaattggt
     4861 aatccatttc ttgcattact aaaaacggcg atgacaaatt ttttttattt tcgattatct
     4921 ttcctttggt agggcgaata atcttcatga gtattcttag taaggttgtt ttccccacac
     4981 cgtttttccc taccaaacca ataacatctc caactttgac atcaaaattt atgtctttta
     5041 gaatattttc ataagtaatt tcttcaactt ttaatacatc tgcacttacc ttttcgatat
     5101 agggaacttc aatcgaacta ttaaaaatgt caaatttcct taatgcgtta ttgttttcag
     5161 tttttaacaa ctgaatagtt gtagttttta cagttctatt tttaacaaat agaacttgat
     5221 caattaattc tttcaaatag taaaaacgat gttcagctat aacaatagta aatcctttat
     5281 tttttaaatc acaaagtaag tcagcaagtt tcttagtcgc tttgaagtcc aaatttgaag
     5341 acggttcatc caatataatt aatttagagt ttagcgataa actacatcca atagaaattt
     5401 tctgccgttc accacttgat agcgaaaaaa tgtttttatc taatatattt gaaagatcta
     5461 ataattcagc taattcattg attcttttat ccatatgctc ttttgtaaat ccaaagtttt
     5521 ccatcgaaaa tactaactca ctcgttgtat ttgttgtaaa gaattgtcct ctaggatctt
     5581 gacttacgta gccaatattt tttgatatac tttcttgtgt taaggattgt agcgagttat
     5641 tttcaaataa aatttcccca accaattttc cgtcataaag tcttggaata agtccattca
     5701 ttaactttaa tagtgtggat ttcccactcc cagaagaacc agtaatcaat gtaagactgc
     5761 ctttttttat tgaaaaatta aggtcaacaa gcgcttgttc cttaacatcc ttatatgaaa
     5821 aagaaacatt gttaaattca aacaattctt tcacctcaaa tcaaaatact taagaaaaaa
     5881 atagtaacgg aaaacaggat gatatagtct aataagctca tgtttgtttt atagtaagaa
     5941 cttcttttca caggagattc tatccccttt gttattgcat tagcggtcat ttcttcagca
     6001 atcatagttg cacgtataag aacgggaact aacagaaatt ccaaatattg cagaggctga
     6061 aaaaaagaca agcgaatgtt tctcattttt aaagattctt taatcattct tatttcagaa
     6121 cgataagtcg gaaagaatct gatcactact gtaatactta acattatttt tttcggtaaa
     6181 tgtatttttt ctaaagagga taataattca ttgctagtat agacactaac caacaaccat
     6241 gagatcatta cgaccggcaa cattcgaaat acaatatata aggatgtccc aaaaaatata
     6301 gtaaaaaact ctatcttgat agcatcaata attttcatta ctaaaaacag aactgaataa
     6361 atcaagatga aataaataca tgtctttatt ttacgaaaca tcaatactaa aactgtagca
     6421 ataatgaaac accccacttg aaatatattt ccctttccta aaaaaataat gaccggaaaa
     6481 aaaatattta aagtaatcaa ggttaacgga ttgatttttg acactctttc acctccaaaa
     6541 aataagatcg cactgttatc ttaagctgac aaaaatgcac cgttattcag ataacagtgc
     6601 gatcttatca aaaagcataa ctgagaacaa ttctcaatgc aagctttttt ttaattaact
     6661 cagtaattca atccacccag gaacagaaaa ttgatacaat cttctggtta atagcatagt
     6721 cttttctttt gaatagctat gcttcaatat atcatagaat gtagcgtaga atgagtaaat
     6781 gtagaagtgg atttcttctt cattaaagac taaattttga ttgatcattc cgatagtctt
     6841 taacttatct agacaacaga ctgtcttttt tgtcacaaat gatgtaattt tttcaacaat
     6901 atcttgatat ttggttccag ctgattggaa taaaaccaaa tcgaatatac gtttattctc
     6961 aaaaatataa ttaataaatg gatctaattc attgaagttc tctctccaac ttttctctat
     7021 atctatattt tctaagttta agaggtattt ggtaaactct tcattataca tattaataag
     7081 cgcattaata tgcggctgaa taatttcttc aaataacgct tccttagaag taaaatgttt
     7141 ataaaaagca cccgtagtta cgcctgcggt caagcacagt tgccttatct tagtttgctg
     7201 aaatccttct ttttcaaaat ggcttagtcc actttctatt aatttttggt gagttgtaat
     7261 ataatctctg gtttctatgg gtacttcctc ctaataagat gaattaacta tattatctta
     7321 cacaggactt gaagtttcaa tcgttaacgt ctattactga actcattcct tagagctaaa
     7381 ctaatgagaa agagcaaaat aactgataca aaaagcaatc ctacaagaat taatagactc
     7441 atctaaatca ttcacctttt ctaaaataat ccgagaaaga tttaaaaaaa ttatatccag
     7501 ctattagggt aagtcctatc ataatcactc caatagccat tttcttatcc tccctaaaaa
     7561 taaagtcttt tacttaaaac cttttttgta atcgtcaata aattttttcc ctttatcagt
     7621 taattgaaat cctatatcta aatagtcctc atatctaagt ttagccagca tctcacttac
     7681 agatgctgga ctaacactta gaacttttgc taaatcatta ttttttaatt tcttttttct
     7741 ttttgataat tcctgaattg ctagtaaata aattagtata gtagtcgttt taatttgtac
     7801 catacctacc ctccaaatta tttcgaaagg ccttcagcaa ttttatccag gttccatttc
     7861 atcatcgcat agtaactatc accatcttgt cctttttctg caattgaatc agtaaaaatc
     7921 gttgaataga taggaatatt ggtatctttt gatactgttt tcattggtct atcgtccaca
     7981 ctgctttcta cgaataagga gggaactttt gttgtgcgta atttttcaac taagtgtttt
     8041 atttgatctg gtgttccttc ttcttcagtg ttgatttccc aaatgtaagc agaaggcaca
     8101 ttatacgctt tcgagaaata tttaaagcat ccttcacttg taacaatcat ttttttatca
     8161 ttcggaattg aagcaaattt agatttagct tctttgtcta gagaatccaa tttttcaata
     8221 tacttatcta gattttcttt atagaatttt ttattatcag gatctttttc cgctaactgt
     8281 ttttcaatat ttttagcgta aataataccg ttttctaaat ttaaccaagc atggggatct
     8341 tccttccctt tctcactctg accctctaag taaataacat ctatgccatc acttgctgca
     8401 aaatagtctt tgttttcctc tttgttcgca ttttttacta attttgtaaa ccaagcattt
     8461 cctccagttt ccaagttaac accgttataa aaaatcaaat ctgcttttga agttttttga
     8521 acatcttcag gcaaaggttc atattcgtgg ggatctttcc caataggtac gatactgtgt
     8581 aaatcaattt tatcttttgc tatattttca gtaatatctg ctaaaatcga attagtaact
     8641 actaccttta atttttcgtt cgaagccact gtatctttgt ctttactatt tgttgaacat
     8701 gccccgaata taaaaagagc aatcaaaatc cccagacttc ccagtactgc tttccatttt
     8761 ctcatcataa ctttctctcc ttctttctta aaaatttttg ttttggtgag attagaaaac
     8821 taattacaaa taagaatgcc gctgttaaaa caatacttga tcctgctgct atgttaaaac
     8881 tataaccaat gaacaaacct agcaatgatg agcacgctcc gactgtcgcc gaaataaata
     8941 tcatagtttt taagctgttt gcatataaat atgctgtagc agctggtgta attaacattg
     9001 caacaattaa tatagttccc acactttgca tagctgttac tgctactaaa gttaatagaa
     9061 tcattaatag ataatgataa aaactgacat tcatccccat tgcttttgcc attaatggat
     9121 caaaagaagt gattaataat tctttaaaaa atagaacaac tgtaaccaac actaaaacag
     9181 aaacgccaat tgtaatccac ttatcaatat cttgtacagc taaaatattt ccaaataaga
     9241 tatgaaataa atccgttgag ctatttgcaa ctcctataag gataactcct aatgctaaaa
     9301 aagaactgaa agtaatacca attgctgtat ctccttttat tacactattg ctttttataa
     9361 aagtaataat gatagaagct aatagaccaa atacaatcgc accaataaaa aaattaatac
     9421 ctaaaatata agaaattgct actcctggca aaacagcatg agaaatagca tcacccataa
     9481 gagacattcc tcttaaaata ataaaacaac ctactgttcc agaaacaatc cctataacta
     9541 cagatgtaat tagagcattc tgtaaaaagt gaaagtcata cagaccatta ataaaatttt
     9601 gaagcatatt attccccctt gtatattaga gttagggttt taaccttccg gttttgattg
     9661 gataacccta tgaaccatcg ttattttaat ttggtattaa ctcatttctt ttgagataat
     9721 atatttattg gattgagagg ctaagccgtt ccccccttgg gtcattgaac ccgcactcga
     9781 gagactggct cctctctctg ataagtgtat tgcgtatgag ttagatgttg aaagtcctta
     9841 ctttactccg tatctcgtac aaggtagtga cgcttttcag ttgagtggat ttcaatccaa
     9901 aattcttttt ttgaaaggtc agatatacat gtacttttta ggcattgata tcggtaaacg
     9961 cactcacgtt gcttctatca tgaacgagga aggaaaggta ttactaaaag gtttttcatt
    10021 tcctaacacc actgaaggag cagagtcatt aattgagcga atggtcgact attccggagc
    10081 acccagtgac tttgttatag ggatggaagc cacggggcac tattggctgt ccatcttttc
    10141 ataccttcac gaatcagatt atttgattca cgttgtgaat ccccttcaaa cagacggatg
    10201 gcgtaaaggt acagaaatac ggaaacgaaa aaacgatatt attgattctg ttttgattgc
    10261 tgacttaatg cgctatggct catttgtcga aacggtctta tccgatgaaa atgttttttc
    10321 tttgaaacaa ctttctcgtt accgaactta tttagtaggt acagcgagcg acttcaaaag
    10381 aaaaattata gccgtattgg atcaagtctt tccagaatac gcgacgattt ttaccaaaca
    10441 gggcgttttc ggaaaagctt ctaaagagtt attgctggcg tttagtgccc cgatcgactt
    10501 agaaaacatt tcctcagaaa ctttggccca atacttagct gagttaagca ggaaccgaat
    10561 caaggcagaa aaagcggacc aattgaagca agcagcttct aactcctttg gagtaaaatt
    10621 tgctcaagaa gcgttcacct tccaactacg ttcaatgatt gaacaattaa aattcattga
    10681 aagccaaata aaggaaacgg aaagagaaat caagcacata atggacactt taaattctgt
    10741 tattctcaca attcctggaa ttggtcctat aaacggtgcg actattcttg gtgagatcgg
    10801 agatattcaa aaattttcta acccgaaaaa actcgttgct tacgctggga tagacgcttc
    10861 cgtgacacaa tcagggcaat atgaggcaac gcataatgtt atgagtaaac gagggtctcc
    10921 atatttgcga aaagccttgt tttcggcggc tttagtagct tctcaatgtg atcctgtttt
    10981 tagtgcgttt taccagaaaa aagtttccga aggaaaacat catctaactg ccttaggtgc
    11041 ggtttctcgt aagctttgtt acgtgattca tgctattttg actaaaaacg agccttatat
    11101 aattgtttct gattagctat tgaacattca aaaaaactaa tggtaagaag cttatttgtt
    11161 gtaccctttt ttcggaatta tctgttataa aatatttttt gatttggcta atttttactt
    11221 gactctatat agttagtctc tccaataaat atagtatctc cataggcttt ttttaaattc
    11281 tcttcattaa atacagattc tacacttccg tgagcaatta gatttcgatt caaaagaata
    11341 atattatcaa aatacttctt taccttgctt aaatcatgat gcacaattag cactgttttt
    11401 ccctgatgtt tcaattcttt taacgtatcc ataattattc gttcactaac taagtctatc
    11461 cctacaaatg gttcatctaa aaatatgaaa tccgcatttt gagcaagaca tcttgctaaa
    11521 agtacacgtt gaaattgtcc tccagataat tctcctattt gatgattaga atattttccc
    11581 atatcgacct tttccaaagc ctttgaaact ctttgccatt ctgcattttt aattctttga
    11641 aaaactttca ttccggcata tgttcccata gatacacatt cttttacttt tattggaaaa
    11701 gtaaaatcaa tatcagcttt ttgctctaca tatgcaatct tcaccagttt tttattgata
    11761 tcttcattat taatggagac ctctccctga tgagggataa tatttaacat tgctttaagc
    11821 aatgtagatt ttccagcacc atttggacca ataatacctg ttaaagcacc ttcttgtatt
    11881 tttaaagaaa tctcgttcaa tgctaaaaaa tcgttataac aaacattaag ctttttcact
    11941 tctaacataa ctttctcctt ctaaatgata atgattatca cgatcatatg gtatacaaaa
    12001 attatatttt agtcaaccct aaattttata atttagattt ttttctgttg ctgaagatta
    12061 gaatgacaaa actatttgaa actacgcgta tagtaagtag ctttcaaaat atataaaaaa
    12121 ggagcgttct caaatgagaa catgctccta aaactacttt attggcgtat ggaaaaatta
    12181 tacttaaagt ggatagcggg ttgaataagt tgataagcat caaaacattt ataaaaatta
    12241 ttcaagacta tgtctgttcc atatacaaat atgaaaatca gtaaactcca tttaactttt
    12301 ttcgtagtgt gtctttttat acatgtttat cgttattaat agtgaatagg aaaaaaccta
    12361 tttttgatca ttgacaatta aatacaattt ttgaataacg atccctgcta ttcgagctag
    12421 aaactcaagt acgccatgac ctgattagcg acaaatactt agagatttct ttttgttctg
    12481 ggaaaacaaa atgccatgac aatagcagca aataatgata cttccgtaag gctcgccgta
    12541 aactggggag aggtgaaatt cctatgtgct tacccaaagc aattcaaaaa ttctaatctt
    12601 ttttaggaga tgattttata aaattgagag tctacttgaa taaaaaacaa acctgtgagt
    12661 ttctaggaat tgataataat actttagata agtggattcg tatatataat tttccagtaa
    12721 tcagaattga cggtatagtt cgctttgaca tagaggatat caaagatttt atgaatacat
    12781 ttaaaacaat ttgaaaattt cttctcgccg catatactaa gaatagcgaa atatactgcc
    12841 ttacttttta agggagtgag gaattttgcc tacaaaactt tcaaatggga aatataaaac
    12901 taatctgagg tatccaaaaa aattcagaga aatcactgga attacatcag aaaagtatca
    12961 aaaagtattt ccaactaggc aattggctat taaagccgaa aatgcaatga aaaggaaaat
    13021 tgaaacagtt ttaagagagg agaatgcaaa ttcactagaa ttaaaaggaa aaataaaatt
    13081 taaggaattc tatgaatcaa aatggcttcc tagatatgaa ctaggtcaga ctactagatc
    13141 aaaaagagct ccaagttacg taacaattag taatactaaa gatatattcc gattgcacat
    13201 ccttccaatg tttggtgagt atgcaatgaa ctatctaaat tcaaatactg agataatatc
    13261 agatgaatta acaaaaaaat cgaaagaata cgcaaatata aaaattatca aaggatatgt
    13321 ccgttctatg tttgatattg cagaaatact aaattatatt gaatttaacc gaactaccaa
    13381 aattattcaa tgtatcactg cacctaaaaa aattgcttta gaagaaagaa ggatacggga
    13441 aggtaatcaa gcattatcgt cagaagagct tattgcttgg atagaagcag taaacactga
    13501 cttgaataat cacttgctta ctcttcatga ctatactctt ttcatgctta ccctatatct
    13561 tggtgataga aaaagtgaga cgtatgcttt gcaatggaaa tatatcgact ttgagaaaca
    13621 aacggttcgc cttaaacatg ctttggataa atatcaaaaa aagaaattta caaaaggtcg
    13681 aaaggatacc gtaattcaag tacccgaaat tgtaatggca ttactaagca aatggaaatc
    13741 agtgcaagct gagcaattgt tgagattaaa aattaatcaa acaccagatc agtatctctt
    13801 tacctatact aaaccatccg gagaagtaaa ttgccctgtt cacgctgatt acctaaacta
    13861 tcgaatcaat tcaattaaaa gacgacatcc tgaattggct catttatctc cacataagct
    13921 tcgtcatacc tatgcaacta tagctagaca aggcggagca aatatgaatc aaatatctaa
    13981 tgctttaaca cactcagata tttctactac aaagatatac gtaaacacac cagatgtagt
    14041 tgataagact gttttcgaag catttcaaaa aggattaaag aactaggatg aatgtgttct
    14101 cgaatgtgtt cttaaactaa aaaaagacac tttccaaata attgaaaagt gtcttgaaac
    14161 attgatatac aaagaatatt aacgttttga aaactgtgaa gctttacgag cttttttaag
    14221 acctggtttt ttacgttcga ccatacgtgc gtcacgagta agtaagccag cacgtttaag
    14281 agctaaacgg aagtcaggat caacttctag caatgcacga gcgataccat gacggatagc
    14341 tcctgattgt ccagcgtatc ctccgccgtt tacgttaaca aatacgtcat atgcgccttt
    14401 tgtttcagta acagcgaaag gttgattgat tacttcacgc aagtcagcat gtggaatgta
    14461 ttcttcaaca tcttttttat ttacagtaat tttgccagtt cctggtacta gacgtacgcg
    14521 agcaactgcg tttttacgac ggcctgtgcc gatatattga acttgtgcca atgaaattcc
    14581 ctcctattag attaagtttg tgatgtctaa aacttctggt tgttgtgctg catgtggatg
    14641 ttctgctcca ccgtatacgt tcaattttgt aaattgtttg cggcctaaag tgtttttagg
    14701 aagcatacct tttacagaag tttcgatcaa acgacgagaa tttttagcac gcaattcgcc
    14761 agcagtgatt gatttcaatc ctcctgggta gttgctgtga cggtaataaa ttttgtcagt
    14821 cgctttttta cctgttaatt tcactttgtc tgcattgatg acgatgacga aatcgccagt
    14881 atccaaatga ggtgtgaaag ttggtttatt tttaccacgt agtacagatg caacaactgt
    14941 tgaaagacgt cccaatggaa catcagttgc gtctactaca taccatttac gttctacttc
    15001 gcctggtttg gccatatatg ttgtacgcac gttattttcc tccaatttaa gttctgatgt
    15061 ttgacataca cttcgagttt ccggggctct ttgtggggca aacaatacca tttaacatat
    15121 tacccgctaa tctagtcaat gtcaacgttt ttctgcttga ttgaaaaatt tatatgaaac
    15181 tttacttctt ttctttcttt tatataaaag ggtcgtttcc tgtcaaaatg aaaaacaaaa
    15241 agaggctgtg acaaaagtct tgtcacaacc ccttattttg aataaacggt gttctcctgc
    15301 caactcctcg gtcacaagtc acaatatcca taaaacataa gaagctgttt tttaaaattg
    15361 tttcttgtga ctcggagctg aacggcaggc ttacaacctc ttggtaaacg gtgttcaatc
    15421 agctgaccct cggtattagc tcaaaaaacg gcaaaatatg aggaactatt ttgacgtttg
    15481 tttctctaat actcaggtca aaacgctgat ttcacaacct ctttttcggt caagttcaac
    15541 aacagttttt acgcgtcgat ctctggcgct ttgcccaaat gagcttggat catccagata
    15601 cgtttttctg tggctgtttt gaattcgata aagatatctt gtgttggatc gtcgccttct
    15661 tctccagaaa cttcgattcc tttttggtaa agatctgcta gataacgata gcctgcaaca
    15721 agtgtttcca aacgttctgg aatagtacga tcccagcggc caatttcatc agggattttt
    15781 gtgttatctg caaattcacg caatgtagaa taaggtgaac cgtctaatgt gatcaagcgt
    15841 tcggatactt catctaactg agcgttcaaa tcatccatga actcatccat cattgggtgc
    15901 aatgtaagga aacctggtcc tctcatgtac caatgtgttt ggtgaacaac aacagacatt
    15961 tggcttagat ctgcaactaa ttgatttaat acttctttgg tttgttggaa tttcatcttt
    16021 cttgcctcct aacattttct tacacttaaa ataatagtag actttcaatg aaaagtacaa
    16081 caaaatcatt tacctgagaa cgattttcag ttcgcttttt tatccgtaaa gccaatcatt
    16141 tttcagaatc agctaattct tctcgcagtt gagcaaattg ctgataagtc tgtgctaaat
    16201 gcttttgtgt cgaaacaaat aatggataga ttttctgata ttttttatga tcagtttctt
    16261 gtactccaac ttgctctttc aattctatca attcctgtgc ttcactgata ctttggatct
    16321 ttccgatgct tctccagcct aaaatcacag ctcctaatgc ggatgcttct gtgacagtag
    16381 ggaaaacaag cgggtaaccc agtacatcag ccatcatctg acgaaaaatc ggagattgag
    16441 caaacccgcc tgtagcacgg atctctgtga gctgattttc ctggcaaact ccttttaaaa
    16501 tccgataaag gttgagacag atcccttcta gaatcgcctt catcatttct ttttctgtat
    16561 gttgccgctg taaaccgata aaactgccaa acgcatctgc gtcccaaagc ggtgctcgct
    16621 caccaagtaa atagggatga aaaatcagac cattggcacc cgctggcaca aaagcgatag
    16681 ccgaaagcag tgcatcatat ggattttctc ctttttcttt agcagattga acgacttcct
    16741 gtaaaaatgt atgccctgcc caatcaaaga tgccagcacc attgctagtc gctcctccca
    16801 ctacccaatg tttctgatcc agaacataac aaaacgtctc catttctgga tggaactgag
    16861 gctgagtagt aataaaacga agtgctccgc tcgttcctac ggtcaaagcg gcgatcgtat
    16921 caccaaaagc acctaaccct agattagaaa gcggcccgtc tgcccctccc aaaacaaatg
    16981 atatatcatt tggcaaacct agttctgctg ctgtttttga tggtagacct gttacttgat
    17041 aggtggaagg aaagacttgc ggcaattgct ctattcgaat gttcaagtag tcaagcactt
    17101 cttctgccca ttggaattca tggatatcaa aatatccagt tcctgaagct gttccgtagt
    17161 cgctgatcag ttcgccaaac aatctataaa agatatagtc tttgataccg acaaaataag
    17221 cagttttttt gaataattca ggttggctgt tttgcagcca cttgattttg ttcaatggtg
    17281 tcattggatg aatcggcgtc ccagtctgcc gataaaattc tttgccaagc acggtatatt
    17341 tcagtttttc tgcttcgtcc gctgctcggt tatctgccca agtgatcatt cgagataacg
    17401 gtgttttctc ttcatccaac aatatcaggc catgcatcgc agaggagaag gagacaaatt
    17461 gaatgattgt gtctgaaggc aactgtttaa ttacttcttt tataacggtg cagacacctt
    17521 gaaagatcaa ttcctgatct tgttctgcca tcccttgtgt ttcttggatc aaagggtagc
    17581 gaaaataagc ggatgctgct tcttgggctt catctgtgaa agcaactgct ttggtttgtg
    17641 tggttccgat atctaatccg attgaaacgt tcattttttc acctcaaatt ttatgtatgt
    17701 acaaaaattt agtttaagct tgcgtatctt ggttttgaaa agggggagat ggcgtgttac
    17761 tttattttat cattggttgc tgtatcggat catttttatg tttaaccgcc cagcggattc
    17821 cgttaggtca ctctattatt tatcctagat ctcattgtgt caaatgctgt cgttcgcttt
    17881 cttggtatga attgattccg attctctcga tcatcgtcca acgatttcgc tgccgctatt
    17941 gcaggtgtcg gttgcccttc tactatttgt tggcagaagc cttatgtggt ggtctttttg
    18001 cctggttctt tactttttct tccgcaagaa atttttcgac gttcatatgg atgctttcgg
    18061 ctttgctatt ttcgttgatg gatttatttt acttcatggt ccattctcac acgctattct
    18121 gttcttgggc aattttatgg attttttggt tgcaggccgg cgtcttccaa tggcaaagtg
    18181 tgctgttaac gtttatcgta ggcggtgtgt gccttcgcta tggtcaatcc tatctcggag
    18241 ctggcgatac tctgttgatg ctttcttgga gtggtggctt gtctctagaa gagttgcttc
    18301 agatcttgtt tcttgctagt ctgtttggaa tatccgtttt ttctgtttac tttatctgtc
    18361 ataaaaaaaa gttggaaaag ctgcctttca ttcctttttt gagcagtgcg ttgctgattg
    18421 tccttcatct taggtattga aaaaaggttg tgacaaacga cttgtcacaa cctctgatat
    18481 atagtgttct cttaccaaat ccttgtgact tggagctagg cgacaggttc acaacctctc
    18541 cactaaatgg tgttcaatca gctgaccctc agtattagct caaaatgctg gttttacaac
    18601 ctctgatata cggtgttcca taagtagctt tttcggcttc ttatttcttg acgccccaat
    18661 gtcgacgaag gaaacctgca cgtccagaac cttctcgata aagattgtaa tggagcttgt
    18721 ttttcttgta ataatcctga tggtaatctt ctgcaggata aaattcgctt cttggttcga
    18781 tttttgtcac gattggctta tcgaatcgcc cgctgtcttg caatgcttgt tttgaacgct
    18841 ctgcaatatt tcgttcttct tcatcattat agtagatcac tggacgataa gaatcaccgc
    18901 gatcagcgaa ctgtcctaat gcgtcagtcg gatcggtttg ctgccaatag atttccacca
    18961 actgatcata agaaataact tctggatcat attcgatctc tactgcttct gtatgccctg
    19021 ttgtgcctgt tgttacttgt tcataagttg gatttggtac atgcccgcca gtataaccgg
    19081 atgtcacaga aatgatccct ggctgctctt caaatggttt gaccatacac caaaagcatc
    19141 cgcctgcgaa aactgctttt tttgtcatat aaaatccccc ttttttctca tcataccttg
    19201 atttccaaaa ggaggataac gttttgcttg tgacagaaaa aacggaaact attatatacg
    19261 tgatacggct tctgataaat gccaaaacga acgtacttga tcaaaaacgg ttaaatcagg
    19321 aatcacatat tcagcagaag gaagatttat gttttcacct attcccaata catgcatgtt
    19381 accagccaaa gctgcttgac aaccagcttc tgaatcttca atgaccaagc atgcatttgg
    19441 cggtacattc aattgctgtg ctcctttgag aaaaacttct ggatcaggtt ttgcttttga
    19501 tacttgcgtg ccgtcaataa ggacatcaaa ataacttgtc aaattcgttt tttctaaaat
    19561 gaggcgtgca tttttgcttg ctgatcccaa tccgatcttg atgtttgttt ttttcaagta
    19621 ctcaagaaca gctattgcac caggcaaaac ggatgtttca tccatttttt gaatcgcttg
    19681 aagatataga ttgttttttt gctcagcaaa ggctgatttc tctttttctg agaatttctg
    19741 ttccattttt ccaaatgaca gcaatcgctc tagtgactcg gttctggata ttcctttcag
    19801 ttgctcgttt tctttctcag tgaatggaat ggacagctgg ttagctaaaa ccagccacgc
    19861 ttcgtaatga taacgagctg tgtctacaag aacgccatct aaatcgaata gtgctgcttt
    19921 gattttcatc gattacctcc ttgaaaatga acgacttgaa gtaaagatgc gatgttttta
    19981 gctgtgcgat gaagattatc agtggcttgc tgtaaagctt cttgtaaagg cacagctgca
    20041 ggaaggatcg gaaaaacggc cgaaatgcca acatctgctg ctttttcgct tcctttacca
    20101 acacttccgc aaatagctat cacaggaacg ccctctggta ctcttctagc aatcccaact
    20161 ggcgcttttc cttttagact ttgtccatct agacgtcctt cgcctacgat tacgaggtct
    20221 gcttgctgta cccgtttatc gaactccagt aaatccaata cgtagtcgat gccagagact
    20281 attttccctg aagcaaatgc taacagtcct gcacccattc caccaccagc actactgccc
    20341 gatgcctcga ttacttgagg ggcaaatctc atataaaaat catgcatggc ttggtcagcc
    20401 actgctaatt cattttcttt caagcctttt tgtggtccga aaacaaaaga agcgccttct
    20461 tttccgcata aaagattagt aacatcagta atgacagtga ttttggcttt aatcagctca
    20521 ataggcacgt tcgttttatc aactgtagca attttaccta gattttctcc cagtgcttct
    20581 actttttgat tatcttgatc gtaaaaagca taacctagac cttctgccat gccgatgccg
    20641 ccatcgttgg tactacttcc gccaacgccg atgatgatgt gtcgaacacc ttgttgcaac
    20701 aattgtcgta tcagttctcc tactcctcgc gtggataacc taagtggctg ttgttggttt
    20761 agtgggacat ctttcaatcc gacgatttct gccatttcaa aaatcgcagt ttgaccgtct
    20821 gaagcgtact ggatttcttt gtttttgcca aatgcattag taacgactgc tgtttgccgc
    20881 ttcaacctta aactgtctgc taatgatgaa accgttcctt ctcctccatc gcctataggt
    20941 agcagatcat attcagcctg aacaaaaact tcttgaaaac ctgattgaat ggcttgtgct
    21001 gcctctaagg ctgtcagact ttctttgaaa gaatctggcg caatcagaat acgcattatt
    21061 ttcccctccg ttccaagatc agttcttttt ccagctggta ttggtctcca ttgacaaaaa
    21121 taggtaatgt ttctttcgtc tcttttttta ttactatttg tttttttgtc aaaacaaata
    21181 gcaacctgtg atttttccaa ataaaaggaa aagaaatttt ttcccatgct gaaggaagtc
    21241 ttggagaaat agaaagagtt ccattcgtta ctgtaatacc tgaaaaacca aatataactg
    21301 ctagccatag tgctcctaat gaagcagcat gaattccgtc atctgatgaa tgcggatctg
    21361 gtcctaaatc aatcaggcac gcttcttgga ataaatgata cgcccattcc atttcttgga
    21421 tacggcaagc ctctatggcg tgaatcgctt tactcaacga tgagtcgtgg attgttttgt
    21481 tttcatagta atgcaaattc ttagaaacga ttggttgaga aaaatactca ggtaataagt
    21541 ataacagcat gacaagatct gcttgcttgc tgacttggag ttcatttact tcgctacggg
    21601 cataatcaag taaaatagac tggctgccag gacgttcttt gtaagtggtc aaatcaataa
    21661 ctggcttact gagatacgtg tcatcttgcg gaatcagctg ttctttgtta ggcactggca
    21721 aatataactt atctaaaaaa ttttgacatt ctttcaaaaa aagcggatcg ccagcttgat
    21781 atttaacagc taaggccaca ttataatgcg ccagatagtt cgtatatgca ttattgtcga
    21841 tatattctgt gtattcatct ggagcaatga ctctgtgtat ctctaaatga tcatcgactt
    21901 ttacagctct gctcagccaa aaagctgctg tttcatgaat gagcgttttt ccctttgttt
    21961 ctaaaaacga ttgatcctct gttgcttgga catactcttg aacggcataa gcaaggtctg
    22021 cactgatatg atgttctgcg gcagctgaag caacttcttg tcttgttccg gttttgatat
    22081 tcaatgcagc aaatttgggt gtctcttcct gaccagtgtg tgcgctttcc catgggaaaa
    22141 gtgcaccttg atagtgataa tctcttgctt tttgccgtgc gccttctaat cgatcataac
    22201 ggtacagcag caaattcttt gctacttcag gaaactgata taaaaagaaa ggcaggataa
    22261 aaatttccgt atcccagaaa acatgccctt tataaccttc gccagttagt cccttcgccc
    22321 ctacactaac acttggatca ttgcggggag tcataatctg taaatggtaa gcagcgaagt
    22381 ccatcgctaa ctgatcgaaa gaagaatcgc cttggatcgt tatccgatgc tgatgccaaa
    22441 aatctgtcca ataagacatc gactgctcta aaatttctgt ataactaacg cttttctggg
    22501 cttgggcaat acttttctta aacgggtctg tttgctgaag agaggtagag agcacgatga
    22561 tcttctccag cgtaaaggac gtattttttc tgatcttttc tgaaaaggaa gcggtgatcc
    22621 ggcgattttt tgcttggaat acacctgctt tattgaattt agctgcaatc ccaatatcaa
    22681 ttttactttc tgttgtctgg taggatgcac tgatcaaatc gtcaccaaat actcgcagtt
    22741 ctttttcaac caactgctgt gtaccaaaat tggtttgctg tccatcgata cccgttttca
    22801 catctacttg gcagtcttcg gtcaacggct tgatgaccac tttcagggct gcctgatgga
    22861 gattattttg atcagcaaca cgacaagtaa tgacttccac tttttttcct tgagcagttt
    22921 caatgagcgc atagcgttta agctctccca tttctaaatc tagtgcccgc tcgtatgcaa
    22981 gaactttcat cgtctcaaga gaaaaatgtt caccgtcgat ttttatttcc catctgatga
    23041 catctgggag attcactaac tcggctgatt ctgctcctaa aggtcggtta tatacaccag
    23101 ctgcaaacat tccccttact tgattccgat agtcttcctc ctggcttcct ctgataccaa
    23161 aaaatccatt tccaatggtc atctgactcg catacttatt gatatactct aaatcaaact
    23221 gtttttcttc tactttcata aggtaataac ttctcctgtt tctgccgaac gatataaatt
    23281 ttccaccaga ttctggatga catatccttg ccagccatct gcaatcatct gagtctggtc
    23341 accgagcgcc cgattcacaa aatgagccat acttagttca tgtgggtcat taactggcgt
    23401 ggtcttttgt aaggaaacca gctttccatc tacatcttcg aatagttcgc ctggatacag
    23461 attagcacct gcctgatcgc cacaaaaagc cacattcagt ttgtcttctc tgatattcaa
    23521 agcaaacgaa gtattcagtt ggatgatctt gccgttttct aattccagtg tgccaaaaat
    23581 tgcatcttct actgtgaatt tgcttggatc ccatttcccg aatttccctg aatttttttt
    23641 cgtaccaatt ttttggaagc tgtacgcccg aacgcttttt actttaggaa atccagtaat
    23701 atacatcgct gtatcaagca tgtgaatgcc ataatcgatc aaaggcccgc ctccttgaag
    23761 ttctttgtcg ataaacgttc cccagcctgg aacaccagac cgacgaagcg cattcgcttc
    23821 tacgtaataa atatccccga gaacatcaag atgattcttg atcattgttg cttcgtcaga
    23881 aaaacgatgc tggaatccat aagccaaaat ctgcccgttt ttatcggctg tctctgccat
    23941 ctttcttgct tgatcagctg tcatagctgg tggtttctcg cacatcactg aagcattagc
    24001 ttcgagggca gccaatacat gttcgaagtg aaagcgattg ggtgtacaga cactcacgat
    24061 atcgggagaa atctcattca gcatttgtgt aactgatgta tacgcatgag aaaatcctgt
    24121 acgtcggcaa aagtcttctg ctcgctggct gactggatca accacagcgg ccaattctaa
    24181 gacatctgat cttttttgat aataagcagc atgtactttt tctgctactt gtccagcgcc
    24241 tatgattgct actttcttca tttatttctc tctcctttgc ttatttactt attgttattc
    24301 tttctctatt ctttctctaa atcatttaaa tgacgcgctg tttccagaca gtttttcaag
    24361 tattgcaatg attcctgata aattttcact tcattttctc ctcgcaaacg acattcatat
    24421 accatataac cttcatactc attttgaagt agcgtttgaa aatggcgagt aaaatcaatt
    24481 gcgccagatc ctggttggta gcgatgatta tctgctaaat ggatatgacc cacatactct
    24541 ttttgcgtag tcaatgcttt tgaaatatca tcttcttcaa tattcatatg ataaaaatca
    24601 gcgatgatct gcacatgttt caattgatta gagtcaatgt aatgacgcgc atccgctaac
    24661 aaattgatca tatggtcttg gtatcggttc aaaggctcca aataaataac cgtacctgtt
    24721 tcttcggcta ctttatctaa ataacgaagt gattcgctga ctgctttata gtctccttct
    24781 ttgcttcggg gtgaaaccat cggcggtaat cgataagtga acattcccca agctgctggg
    24841 ataacgattc ctttgcctcc aacctcgctt agtgcacgca aaatctcagc aatttgacgt
    24901 acaccattaa gacgccgttc ttcgataaag tcaccgatcc acccatcgta gccgttacaa
    24961 gctgtcacta ctgggatccc tgtttctttg attgcctgtt tgactgtgtc gatattttct
    25021 attaacaact taccgtcgat ttcgtattct tcaaatccac agtctttgat aaatctaaat
    25081 ttttctaaaa tgtctcttgg gaaaaatgct tgatcttgcg taccgaattt cattgttctc
    25141 ctcctcggac ttgaacgccc attttgatac tttcttctgg gtgctggtct acataacgca
    25201 tgtaagcttc tgcgctttct gcaaatggca caactggatc aatgatttct tcacaatcca
    25261 agtaaccgtt catcaataat tcccaacatg tgtcctcgat tcgtttacgg ttccatcttg
    25321 ggtaatctgg gtttggttca ctagatgctc gagcaaagac gatttttgca ttattgaaat
    25381 gtgcttcgcg accaagatta aacccagctg gaaaaggttt agcaaaggca acataagaaa
    25441 tgatcccgcc atagccgatc cctattaaag aagcttgtaa tgcggcagca ctgccactcg
    25501 tttcaataac tgaatctact ccacgtttat ctgtcaattc ctttagacga aaaccgacat
    25561 ctgctttcat aggatctagc gtgtaatcgg caccgtgttt ttctgctaat tctctacgct
    25621 gcgctatggg atcgatccca acgatggtag tagcacctgc ttttttagct aattgaatcg
    25681 caatttgccc gatagcgcct aaaccgaaga ttgctacagc atcacctgct cgaacatgtg
    25741 cttcccggat accacctaaa gcgaattgag caggatcgta acatactgca tttttccatt
    25801 gatccaaccg atcaagttta cgtagtttat aattatcaac accgtttgta atcagcgttt
    25861 cacgaatggg tccataagtg cagactaact ctcctttttg atactctgtc accaaactgc
    25921 ccgtttcttc gatcgtaccg acaatcatat ttcctaattg aaattcgcca aataccacac
    25981 cgcgttggct tccttcttct cttggcaaga ataggcgcca ttcttctgaa aattcttcat
    26041 cgataaatgg acttaatcct ctaaagtcga caatttctgt tcctggtttt ggagtagcga
    26101 aaattactcg gatacgtact tcgttctttt cgatctcacg gtcttcgtaa tctttgaatc
    26161 cggctattct tggttctaat gcaactaatt ttttcatctt ttctttcctc tttcttttct
    26221 ttttatcctt ttacgccgcc ttcgactaaa tcacctttaa taaatcgttc agataacgca
    26281 tacataatga tgactggtaa agcggtcacc aatgaagcgg ccatcattcg tccccaaatg
    26341 tagtctggtg tactgaataa tgtgttcaaa ccgattggta aagtaaattt ttcggaggtc
    26401 gacaggaaaa tcgaagcaaa taaataatca ttccacgaaa ccataaagca ataaacgaag
    26461 acagaaatga ttccagaaat agccaatggt ataatgatcc gaataatgat ctggatccgg
    26521 ctaagaccat cgatcattgc tgcttcttca atatcagtcg gaatcgtgtc aaaataactt
    26581 tttagcatga atatcgcagt aggaagtgtt tgaacgacca tcgtgataat cagtgctgta
    26641 ttggtatcat acaaacctag accggaaatg attttaaata atggaacaac gatcaaaata
    26701 ccggaaaaca tataaacggt gtaaaagcta gcattgattt tcgagcgagc tttgaagcgt
    26761 agttttgaca aagcgtatgc cccgctgatc ccaatcacta ctgcagttac ggaggctatc
    26821 aaggagatca ctaaactatt tttgaaatac atgatgaatg gaaaaatctc agcattgaaa
    26881 atatcctgat aatgttcaaa agtccattct ttcggaaaaa tagtttgtgt cgttgcaatt
    26941 gcttcttgtg aatccttgaa tgatgtcatc agcatgatca aaaatggaaa caaattgaca
    27001 gctaatagca acaaaatcgt cgcgtaaaat aagattttcc tgctcttttt atttttcatt
    27061 tcaagtccac cttctttcgt gagagcaaga cgaccgctgc aataatgatg aacaatagaa
    27121 tcgatatagc tgctgctttt ccaagatcat tgaacgcaaa ggctgtctga tacaaataaa
    27181 cgcctaagat attgacttta ttcgtcagta gatagacatc tgtaaacata tagaacatcc
    27241 agatagatcg taaaacaatc acagttgcta gtactggttt gattgccggc agtgtcacga
    27301 tcttgaactt ctgccaagca tttgcaccgt ccatttcagc tgcttcataa agcgttttgt
    27361 cgactgtttg caaaatagcc aaaaatgaaa taaacgcata cggatagtat ctccagatag
    27421 caaacaaaac gaccataaag aagctagcaa ctggctggtc gaaccacagc ggtgcttcgt
    27481 tgaaaagctg caacctatct actaacagat cattgacgat tccataacta ttattgaaca
    27541 tatatttcca agcaaaaatc aaagaaatag atggcgtaac ataacttaat aaaatcagtg
    27601 aacgcaccgt tttcctaaat ctgaacttgc ggttaagcaa aatagctacg gctaatccta
    27661 aagctgtact gcctgctaca actaagaatg tgtaagcaac tgttaaacct aaagaacgat
    27721 aaaattcact atcacttaaa atttcaagat aattgcttaa tccgataaaa acggcgtctg
    27781 agttaggatt cagcggcata tcgaaaaaac tgatctgaat attggaaagc attggaatca
    27841 gcactaaaac agctaataaa agcatgcttg gtgctaaaag tcccatggct aattttaagt
    27901 cagaatgttt ccttggacga ttcattgaaa cctccccctg ataatctgcc aatagctatc
    27961 tacttttttc gaacaccatt ggcagaactt cttgttattt cgtatttttt tgtgcgtcag
    28021 ctaaagcttg atcgacatct tcgtttccga cagttacttg gttcactgct tttccgatca
    28081 cacctgagct tgtgatatct cccattttcg tgaaattctt ttccccgact agtccaaaga
    28141 cttgtacttc atcaaaagca ctagcaatct cagatggcag ctcgccaaaa gacttgatga
    28201 cttcattttc tttgtaacca tccagttcga ctacttgttt attcactggt tgagcaccac
    28261 caggagacat caagacccac ttttccatgt ttttcggttg agataagaaa gctgtgaatg
    28321 cttcagcagc ctctttttgt ttctcgtcta gaccagaaga aatcgtcaat ccagatactg
    28381 tgccatagac agcttgatct ttttgtgttg ggatagcaaa accgatattt tctgagttcc
    28441 ccgcttcata aacagaaggc aaaatgtaag ttgaatagat tgccattggt gctgttccat
    28501 tcatgaaagc atctttgatt tctgtcacat cattagagcc tggcatcgtg tattgggata
    28561 agttttgata aaacgacaat gcttctctca tcttttccgt atcgatcgtt acctcgcctt
    28621 catcatccaa aacatttgct ccatttgaca aagcaaattg agagaacgct tgctcactca
    28681 ttgttccttc agcagtaggc atagcaattc catattgttt attctcttta tctgtgaaat
    28741 gttgagcaat ttttaaaata tcatcccaat tttctggttc tgaaaaacca gcttctgata
    28801 atttttcttt gtcataccaa ataccttgaa cccagccgct aattggtgca gcaatatagc
    28861 tttttccatc ttctgaacga acaaggtttt tggctccgtc ataataatta tcttctccag
    28921 cttcctcgat aacgttttgg actgccgtct gatcaatcag ttcatcttta tccatcactt
    28981 tagcaaaatc ctgactgact tccattactt ctggtaattt accggaacga gctaacgtaa
    29041 cgatttttgt attgaacgct gattcttcta ccggcacttg cttgattttg atgtctggat
    29101 tttctttttc aaaatcagca accagttcat tgatcacact taatcgttcc tgttcgacag
    29161 aagagtgcat gaattgaatc gttgtctgtt gtgattcgtt agagctttga ctttcaccac
    29221 aagcagtaag aagaaatcca gtagctagca gacaggtagt aacaataatt tttttcattt
    29281 ttttccacct cttattttat tattttcagc cacatatatt catacggctg gaatatcaac
    29341 tttcgttctt gactgcaatg gataatttgt ccagaaaaca ggtctaggta atctcctttt
    29401 ggtaaaagat aacctgctga ttgattggaa aaattatgga taactaagac tttctcttcc
    29461 ttcgcttcgc gaataaaact gataaaagaa tctgctgagt ccagtaagta aatcaaacta
    29521 ttcggatgga aggctttttc tttttttcga atagatagca tctgggtcaa ttcaccatat
    29581 actgctgttc ttaatggatc tgtctgcaac tctttctcaa tatctgctaa caaaaatttt
    29641 tgccgattga tttttcgatt ctctcctgtt ttttctacgc ctttgtaatc atttcgactt
    29701 cccagcacac tttgaatata aattgccggc acgcctggta acgttaccaa aaatgaatga
    29761 gcagctaaaa agcgtttgct tctccattcc gtcgtatctg ttggagaact taacgcatct
    29821 agatacgtag cgtttatctc atatggactg gtcgttccat ctgggttttt cttgtagttt
    29881 actcgggcac cctctttctt cagctgttcc actaattcaa ggatcgtttt ttccggcaga
    29941 atacctcgta ccggattcaa tccgataccg tcatgggagg ctaaaaaatt aaaaaaagtt
    30001 gtttttttcg atgcgaaatc gatggttttt aaccattctt tcaacttact tgtattaccc
    30061 gaacgaatcg cttgaagggt caaaggtggt agcgaaaact gatagaccat ctgtgcttca
    30121 ttctcgccat tcccaaaata actgatatta tctttgtgtg gcacatttgt ctcagtgatc
    30181 aataccgttc ctggagctgc ttcatcagcg attgcacgga ataattggat gattttatgc
    30241 gtttctggca ggtgtataca agaagttcct agttctttcc ataaaaatcc cacagcgtcc
    30301 aagcgaataa atgaagcgcc tttttctaag taaaacaaaa gaatatcgat cattttcaat
    30361 aaaacttctg gatttttaaa attcaagtct acttgatctt cgctaaaagt cgtccatacg
    30421 tgtttttctt tcccgttttt gtcaatgaac gttgtaagta acgggctggt ccttggtcta
    30481 gtcacgctgc ttgtatctgt atccagtggc aaatcaataa aaaaatcttt gtacgtatca
    30541 ttcaagttta aatattcctg aaaccaagta ctttcggcag acatatgatt gcagacaaag
    30601 tcgaacatta accgtgtttc gcttctcatt tcttctatat cttcccatgt gcccaaacgg
    30661 tcgttgattg cctgataatt tacaacggag aaaccatcat cagatgtata tgggaaaaat
    30721 ggcaagaaat gtacaactct aaatgtatct gccaaatact tttgataaaa tttcttaaat
    30781 gtacgcaaag ttggttgctg ctcttcaaaa aattgatccc cataagtaat caagaaaata
    30841 tcttcttcgt cccaatgcag tttgcctgcc tggcctttct tctgctgata aacactgact
    30901 ttttgttcaa tcatagaggc ggttttctca gacaaatctg agtcgcgata aatcgcttgt
    30961 aaaagttttg tatacatcgg attccccttt cttttttggg agcgttccca acgatttgat
    31021 catattatgg aaaacgctta ctgtcaatag cattttttta aataattttg atatacacaa
    31081 aaatacaaat aagaaagctt atgtatcaat aattaatagc ttcttaaaaa aatatggtct
    31141 ctcatgatca tgcaagctat tcctaaattt tcaaaatcat agacaaaaaa gaatgtctat
    31201 tgtactatgg aattattcta aaacgctccc aaaaaggagg tgcatataaa attgaaacct
    31261 actatttatg acattgcgaa aaaagctaat gtctcaaaat caactgtctc cagagtatta
    31321 aataaccagc caaatatctc tgataaagca aaagcaagtg tacttcaagc aatcaaagaa
    31381 ttgaattatg aaccgagcaa aattgcaaga ggactgtcag gaaatggttt tgacgcgatt
    31441 ctagcattat ctcatcgtac ttctcatacg acctatggca atcctttttt tcagatgtta
    31501 ttcaatccat ttctgccgtt tctgaacaaa ataacttcga cttgattcta caaacggcaa
    31561 aaacaccaga agaagagcta gaaaaatgcg cgaaaaagat ccaagaaaaa atgatccgag
    31621 gaattattat tttaagctct acgatggatg aaacacttct ttttgaattg gatcaataca
    31681 atattcctat tgtggtaatc ggaaaagtcg gaaacgacta cacgaacatc tactcagtgg
    31741 acacggataa tttccaggat agttacgatt tggtggaaac actgatcaag aatggacacc
    31801 gtcatatcgg ctgtctccat gctccgacag aagtttatgt atccaatgat cgtctcaatg
    31861 gttaccgtca atgcttattt gatcaccacc tagatatccg taatgaatgg attatagacg
    31921 gcggctttcg cttagaagat agcatggcag caatgaatga tttaatgaag ctacgagaaa
    31981 gaccaactgc gattttttct accgatgcat taaaatcatt gagtatttac aaagtggcag
    32041 aacaatctgg aaagcagata cctgatgatc tttcgatcgc aggattcagt gatcccttat
    32101 tgtcctccct attttcgcca cagttgactc ggatagacat tccgacaaat cagttaggaa
    32161 tcaaagccac agaactttta ttccaactaa tccaccacca ataccctgaa gaaaaaagaa
    32221 tcattctttc aaccgagatt actctcacag attcgatcca acaacaagaa atgtagaaca
    32281 gaattataaa agaacagaaa cactgaggat aagtcagtta ctctgttctt ttttcaatca
    32341 ctcatccctc gttaccccct cccggtattt tagcgaattt ttcttatttt ccatctgttt
    32401 tagatagctg tggataacta taatgtttgt gttaaactat tttttccaca gggaagaaaa
    32461 aactattttt aaccacgttg tgtataagtt tttatagttc gtttttttaa acacatttac
    32521 ccttatttca atccatgtta tttggggata cttatctcta aaacataaat agaataacag
    32581 acatgtctac tggttttgtt ttattcgagg aattattcaa taatagctag caaaatatta
    32641 aaaataaccg ctctatcttc ccatcaattt attttgcatt caaaaaatga tctatcttta
    32701 cttttgttga ttgacttctc ttggaagatg atcgttccga taccttaatt ggatacgaac
    32761 cgatgttgtt aagatccttt cccacttttc ttctagttag acaaattatt ttagacaaac
    32821 caaaaaagag gttgtgacaa taatttgtca caacctcttt tttaaaatat ctattttgtt
    32881 tgattgttca ttgcgtcttc tgcagccatt tgcgcttcaa tatctgaaat actgtagaca
    32941 ttttcgcttg ctacaccgac ttcttttggt tccatgtcac gataacgttg cataccagta
    33001 ccagctggga tgatcttacc tataataaca ttttctttca aaccaagaag aggatctttc
    33061 ttaccgcgga tcgcagcatc cgtcaagaca cgagttgttt cttggaatga tgcagcagat
    33121 aagaaactat ttgtttctaa tgatgctttt gtgataccta gtaagacagg tcgagaagtt
    33181 gcaggaacgc ctcctgagac tagcgtattg tagttttgat ctttaaagtc tgcgatgtct
    33241 aataatgtac ctggtaagat atctgtatca cctggatcca ttacacgaac tttacgcagc
    33301 atttgacgaa ccattacttc gatatgcttg tcgccgattt ctaccccttg catacggtaa
    33361 acacgttgta cttcacgaag caagtagttt tcaacagata atacatcgcg aacttgcaac
    33421 aattgttttg gatcgattga tccttctgtc aatggtgcac cacggtggat catatcgcct
    33481 tctgctactt tcatacgtgc tgtataagga acagtatacg tacgtgtatc tgtttttcct
    33541 ttgattgtta cttctttggt acgtgttgca ggatcttctg agatatcgat gacatcccct
    33601 gttacttctg tgatcactgc ttgccctttc ggattacgtg cttcaaagat ttcttggaca
    33661 cgaggaagac cttgagtgat atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc
    33721 gtcaactgag taccaggttc accgattgat tgagcggcga tcgtaccaac tgcttctccg
    33781 acttcaacgt cagagccagt tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt
    33841 tttgtattac atgtgaagac agaacggatt gtcactgttt cgacacctgc atcaacgatt
    33901 tgttttgcga tgtcttcgga aatcaattgg tttcctgcaa tgatcaattc atttgtttca
    33961 ggatgacgta cttctttacg ggtgtaacgt cccactaaac gatcttctaa tgattcgatg
    34021 atttcatttc cctcgcggat ggcttggatt tcaagacctc ggtcagtacc gcaatcttct
    34081 tcacggatga ttacatcttg ggccacgtca accagacgac gagtcaagta acctgaatcg
    34141 gcagtcttca aggctgtatc ggtcatccct ttacgagccc cgtgagttga gataaacatt
    34201 tccaagacgg atagtccttc acggaagttc gaaatgattg gcaattccat gattcgacca
    34261 ttaggagcgg ccatcaaacc acgcattccg gcaagctgtg taaagttgga aatgttacca
    34321 cgagctccag aatcagacat catgaagatt ggatttttcg cttccaaacc ttccatcagt
    34381 ttttgttgga tgctgtcttt tgcagcattc caaacagcaa tgacacgttc ataacgttcg
    34441 tcatctgtga tcagaccacg acggaattgt tttgtaatag tttcaacttg tttatgggca
    34501 ttttcaatga tttcttgttt ttcattcagt acactgatgt cagcgatccc tactgtgata
    34561 ccggcatgtg tcgaatgttt gtaccctaag tctttcatac ggtcaagcat cttagaagtt
    34621 tctgttactt tgaatcgttt gaagacttct gcgatgatgt ttcctaagtt tttcttcttg
    34681 aacggtaata ctaattcttg ctctttgata tgtgcaggaa tatcagtacc agcttcaaca
    34741 aagtatttgt ccggtgtttg gacggtcaag ttgaagtctg ttggttcatt cagataaggg
    34801 aattcaggag gcatgatctc gttgaagatg atcttaccaa ctgttgtgat catcgtacgt
    34861 tctttttgcc attcagtaaa tggtttttca cctaatgagt tagggttcac accgatacgt
    34921 gaatgtaaat gaacatatcc gttgcgccat gcgataacgg cttcgttttg atctctgaag
    34981 accattcctt cgccttcgcg tccttcttct tccattgtca agtagtagtt acctagaacc
    35041 atatcttgag aaggagtaac aactggttta ccatctttag ggttcaagat gttttgagca
    35101 gctaacatca acatacgtgc ttctgcttgt gcttcttcat tcaatggaac gtggacagcc
    35161 atttggtctc catcgaaatc ggcattataa gcttcacata caagtggatg caaacggatt
    35221 gcgcgtcctt gtactaaaac tggttcgaat gcttggatac caagtcggtg aagcgtaggt
    35281 gcccggttca gcaatactgg gtgttccttg attacgtctt ctaaaacatc ccatacttcg
    35341 tcttcttgac gttcgatttt acgtttcgca tttttgatgt ttgaagctag ttcgcgttga
    35401 acaagctcac gcatcacgaa tggtttgaat aattcaatgg ccatttcttt tggaagtcca
    35461 cattggtaca tcttcaagaa aggtccaaca acgataacgg aacgacctga gtagtcgaca
    35521 cgtttaccta gcaagttttg acggaaacga ccttgtttcc ctttcaacat atgagaaaga
    35581 gatttcaatg ggcggttacc tggtccagta actggacgtc cgcgacgacc gttatcgatc
    35641 aatgcatcta ctgcttcttg cagcatacgt ttttcatttt gaacgatgat tccaggtgca
    35701 ttcaagtcta acaaacgttt caaacggtta ttacggttga ttacacgacg gtaaagatca
    35761 ttcaagtcac ttgttgcaaa acgtccacct tctaattgaa ccattgggcg taaatctggt
    35821 ggaataacag ggataacgtc cataaccatc cagcttggtt gatttcctga agcgcggaat
    35881 gcttctaaaa tatccaaacg gcggattgca cgtgtacgtt tttgtccttg tgcagatttc
    35941 aattcttctt tcaattcggc tgcttctgca tctagatcaa cattatcaag taattgttta
    36001 atcgcttctg cacccatagc agcttggaat tcttgtccat attgttcacg tttttcgcga
    36061 tattcgcgtt ctgtcaacaa ttgttttttc tctaaattcg tatttcctgg ttcgatgact
    36121 acatatgaag caaaataaat gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga
    36181 cccatacgtg aaggaatccc tttaaagtac cagatatgtg aaacaggagc tgctaattca
    36241 atatgtccca tgcgttcacg gcgaactttc gaacgagtaa cttccactcc gcatcgatca
    36301 caaacgattc ctttataacg gatacgtttg tattttccgc aggcacattc ccagtctttt
    36361 gtaggaccaa aaatccgctc acagaacaac ccttcgcgtt caggttttaa ggtacgatag
    36421 ttaatcgtct caggtttttt tacttcaccg taagaccagc ttctgatttt ttcgggagaa
    36481 gccaaaccta tttgcatact ttcgaattta tttacatcga tcaaaagggg ttccctccat
    36541 ttcatttaat ggcaaaccgc aagacggctg atcttcgacc gccttgcagc tcatagaccg
    36601 gattagtcta aattatcttc tgcggtttca aagttttgga tgacatcgtc tttttcatct
    36661 tccacttgtt cagcagcttt cttttctaat tctttggcag tttgctgttc ggcaaatttt
    36721 gtcaaagcat caacagtgat caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc
    36781 tctgtttctt cgatatccaa gacacgcatg tccagaccta gtgattgcaa ttctttcacc
    36841 aatacgcgga atgattccgg tacacctggt tttggaattg gttcaccctt gacgattgct
    36901 tcgtatgttt tcacacgtcc gactacgtca tctgatttgt atgtcaagat ttcttgtaaa
    36961 gtataagccg caccgtaagc ttccagtgcc catacttcca tttcaccaaa acgttgtcca
    37021 ccaaattgag ctttacctcc caatggttgt tgtgtaacca atgagtaagg tccgattgaa
    37081 cgtgcatgca atttgtcatc gaccatgtga gcaagtttga tcatgtacat cacaccgaca
    37141 gacacacgtc catcaaatgg ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg
    37201 ctggccatac cggcttcacg aactgtttcc catacgtctt catcacttgc accatcaaat
    37261 actggcgttg ctacgtggat acctaactga cgtgcagcca tacccaagtg taattccaat
    37321 acttgcccga tgttcatacg tgaaggcacc cctaaaggat tcagcatgat atcgattggt
    37381 gttccatcag gtaggaatgg catatcttct tccggcataa tacgggatac aaccccttta
    37441 tttccgtgac gaccggccat tttatcccct tcatggattt tacgtttttg aacgatataa
    37501 acacgaacta acatgtttac gcctggtgac aattcatctc cagcttcacg agtaaagatt
    37561 ttcacatcgt gaacgatacc gccgccgcca tgtggtacac gtaatgatgt atcgcggact
    37621 tcacgagctt tttcgccaaa gatcgcatgc aatagacgtt cttctgcaga taattctgtt
    37681 accccttttg gcgtgacttt ccctacaagc aaatcgccat cttggacttc tgcaccaata
    37741 cggatgatac ccatttcgtc taaatctttt aatgcgtctt ccccgacatt agggatttcg
    37801 cgtgtgattt cttcaggtcc taattttgta tcgcgggctt ctgattcata ttcttcaata
    37861 tggatagaag tgtatacgtc atcttttacc aaacgacggc tcatgatgat cgcatcttca
    37921 tagttgtacc cttcccaagt catgaaacca actaaaacgt tttggcctag agccatttcg
    37981 ccttgttcca tagatggtcc gtctgccaga gtatcccctt tttcgacttt ctcacccaaa
    38041 tgaacgattg gacgttggtt gtagcttgtt ccggagtttg aacgacggaa ttttgttaca
    38101 tcgtatttat ctaatgcacc gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat
    38161 tcaacgacac cgtcatgttt acataacaaa gcagctcctg agtcatgcgc tgatttgtat
    38221 tccataccag taccaaccca tggtgcttga ggattgatca acggcactgc ttgacgctgc
    38281 atgttggcac ccatcaaggc acggttggag tcatcgtttt ccaagaaagg aatacatgct
    38341 gtcgcaacgg caactacttg tttaggtgat acgtccatgt agtctacttt atcaatagat
    38401 acttctaagt tttcactttg agcacgagcc ataacaacgt cttgagcaaa tgttccatct
    38461 tcattcaatg ggctgtttgc ttgggctacg atgtaatggt cttcgatatc agctgtcaag
    38521 tagtcgattt ggtcagtaac acgacctgtt tcacggtcta cacgacgata aggtgtttcg
    38581 ataaatccga atttatttac tttcgcataa ctggacaaac tattgatcaa cccgatgttt
    38641 gggccttcag gagtttcgat cggacacata cggccatagt gggagtagtg aacgtcacga
    38701 acttcataac cggcgcggtc acgagtcaat ccgccaggtc ctaaggctga aagacgacgt
    38761 ttgtgtgtca attcgccaag agggtttgtt tgatccatga actgtgacaa ctgagaagaa
    38821 ccaaagaatt ctttgatact tgccacaact ggacggatat tgatcaattg ttgaggtgtc
    38881 aatgtttcag tatcttggat cgacattctt tcacgaacca cacgttccat acgtgctagc
    38941 ccgatacgga attggttttg taaaagttca ccgactgaac ggatacgacg atttcctaag
    39001 tggtcgatat catcgacatt gccgatacct tccatcaagt tcaagaaata gctcattgaa
    39061 gcaatgatgt cggctggacg aaccgttttt acagctgctt ctggatagcc gtttccgatc
    39121 acgtttactt cacgttcagg gtctcttggt gaaaatactt tgatgacttg gacagtcatt
    39181 ggatctgtga ccacaccgtc ttctgatgga tagtaagtca ctgaatttag gccattatca
    39241 atgaaaggag ctagtgtttc catgacttgg tgagtcagaa ctgttccttt ttcaacgatg
    39301 atctcgcctg tttctggatc aactaatgtt tcagctaatg tcagattcaa tagacgtgtt
    39361 ttcaaatcta attttttgtt tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt
    39421 ggatcgaaga aacgagcatt cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct
    39481 ggacgcaaac gttcgtaaac gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt
    39541 ttatgcaagt ctttttcgac tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag
    39601 atcgtatcat cggaaccaaa tcctaacgca cgaactaata cggttaaagg aatcttacgt
    39661 gtacggtcga tacgtacata agagatgtct tttgcatcag tttccatttc tagccaagct
    39721 ccacggttag ggataacagt agaaccgaat ccttcttttc cgtttttgtc gacttttcca
    39781 tggaaataga cacctggtga acggactaac tgagaaacga ttactcgctc tgccccgttg
    39841 atgatgaatg ttccttgttc tgtcattaat gggaaatcac cgaagaatac ttcttgtgct
    39901 ttgatttcgc cagtctcgcg gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag
    39961 tttgcatcat gcgcacgagc ttctgctact gtatactttg gttctttcaa ttcataatct
    40021 acaaattcca aagatagatt gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt
    40081 tctctaagtc cctcatctaa gaaccattgg taagagtctg tttgaatttc gatcaaattt
    40141 ggtaattcca acacttcact gattcttgcg aaacttctac gttcgcgatg ttttccgtat
    40201 tttactacgt gtccagccaa gctcttcacc cctctaaaat gtcattcaaa aagactaccc
    40261 gatcaattgt tacaataata tttcaaatat tatttttagg taacaacaga cattttttgc
    40321 ggcttttagg caaaaaaaaa ccaaaaatag aacattctct tgaaacctta cttcgtgagc
    40381 ttctactttt gtttccttat attaaagccg aaacggacaa tatttcgttt ctgccttttc
    40441 ttcatcagat agtttttgca acttcatata ctacacttat tttctataaa agtcaacact
    40501 tcctggcgtt tcttctgctt tttcgcaaca ttttcttaat gttttcaatt ttatgttttc
    40561 aattatctga caattcttaa ttgacagacc tttttatctc ggttatactt tagaaaattc
    40621 attttgtgga ggaacttcta tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa
    40681 taacttttac tttagctact ttagataggt ttgtattcat catgatggat acaaacgtta
    40741 aacgacagtt tgtatctatg atggctaaag aactttgtat tgcagcaaaa agccacgtag
    40801 acaaaatgct aagtggctga gcagtgaaaa tacaaagtaa aagtatcaag cattctactt
    40861 tttcaattta ttttccgact tttcaatcca tttggacatt ttgtctgaat ggattttttg
    40921 tttcccaaaa ttaaggagga aaaagaaatg aaaaaaaata taatcatcgg attaggcgct
    40981 gccctgctac tagctttagg aggttgcgca caaaaagaca attccgcaga ggcatcagat
    41041 ggacaaaaaa caattggcgt attgcaactt gtacaacata actcgttaga tgctgcctat
    41101 aaaggattca aagaaggatt agcagaagaa gggtataaag aaggcgataa tctaacaatc
    41161 gattatcaaa atgcccaaaa caatcaagac aacctgaaaa gtatgagtga gaaactcgtc
    41221 aaagaagatc ctgatttgct acttggaatc gccactccag cagcacaatc tttattaaat
    41281 gaaacaacca ctatcccgat gactgtcaca gcggtcacag acttggaaca agcccattta
    41341 gtcacatcca atgaaaaacc tggcggcaat gtgactggca cgacagatat ggtgccaatc
    41401 gaaaaacaaa tcggcttact gttaaatatc gtgccagacg ccaaaacaat cggcatcatg
    41461 tataacaacg gtgaagcaaa ctctaagatc caagctgatt tggcagaaaa agaattgaaa
    41521 aaagcgggcg tcaaagtcaa agtactgaca gcaaattcca caaatgatgt ccaacaagtg
    41581 acgaaaagtc tagctaaaga tgtagatgga atctatattc ctactgataa cacgttcgca
    41641 agtgcggcaa gtgttgtcgg tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc
    41701 gcagttgatc aagtcaaaga cggcggtcta gcaacagtag gaatcgacta cgaaagcttg
    41761 ggcaaacaaa cagggatcat ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt
    41821 cctgtcgaaa cagcgaatga tttggaactg tatgtcaata aagacatggc caaagcatta
    41881 ggcatcaatc cagacagcat caaagaagct gaataaaaca caggaggatt ctcatgacaa
    41941 atttgctctc tcttttctta tcatctgcat cgcaaggggt cttatgggcc ctacttgcga
    42001 ttggtgtata cgtcactttc cgtatcttgg acattgccga cttgactgct gaaggaagct
    42061 ttcctttagg tgcagggatc gcggcagtaa gtattacaaa tggctatcat ccattgacag
    42121 cttgtcttct aggcttttta gggggtgcgg cagcagggct tgtttccgga ctgcttcaca
    42181 caaaattgaa aattcccgcc cttcttgcag ggatcatcac catgactggt ttatattctg
    42241 tcacatcccg tgtgatgggt gcgccgaaca tctctttatt gggtcagcca acgatctttc
    42301 attgggtcga gtcattcggc ataacaaaag acaacgctgt actgatcgtc ggtctgcttt
    42361 ttgctttgat cgttgtatgt ttacttgttt tgttcttacg tacagaaaca ggacttgcta
    42421 ttcgtgcaac tggcgataat ctggcaatga gcgaagcaaa cgggatcaac acagataata
    42481 tgaagatcat cggttatatg atttctaatg gatgcattgc tctttctggc tccttacttg
    42541 cgcaaaacaa cggctttgct gatttaaatt ctggtattgg aacgatcgta attggacttg
    42601 cttctattat catcgcagaa gttttgttac gtaaccagcc actatttctc cgtctcttga
    42661 ctgtcgtttt aggtgcggtc atttatcgtt ttattttagc gttagtcttc gaactgaatg
    42721 ttgaaccaag tgattcgaaa cttgcttctg ctttcgtgct agtgatctgt ctttctttcc
    42781 cgcagatcca gcaaaaattc catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa
    42841 tgacgtctta acattggaaa atctccatca tacctttgaa aaaggaacga tcaacgaaaa
    42901 tcatgtcctg aaaggcatta atctttcctt agatcccggc gacttcgtga cgatcatcgg
    42961 tggaaatggg gctggtaaat ctactttgct gaacagcatc gccggtacat tttctgtcga
    43021 tcagggtcaa attttattga atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc
    43081 gaaatccatc agtcgcgtat tccaagatcc taaactaggg acagccgttc gtttaacggt
    43141 agaagaaaat cttgctcttg ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt
    43201 caaaccacaa gaccgaacat ttttcaaaga ccagctggtt cggctaaatt tggggttgga
    43261 aaatcgttta tcctcagaaa tcggtttgct gtctggagga caacgtcaag ctattacgtt
    43321 attgatggcc acattacagc gtccagaact gatcttatta gatgaacaca ctgcagcgct
    43381 tgaccctgct acttccaaaa cggtgatgga attgacagaa aagctgatca ctgagcagaa
    43441 tctcactgct tttatggtca ctcatgacat ggaagacgcg atccgctatg ggagtcgact
    43501 gatcatgctg catcaaggaa ggatcgtcgt agatatccag caagaggaaa aacagcagct
    43561 cacagtgccc caattattag cgttgttcaa acaaaacagc ggcacggcat taaaagacga
    43621 tcaagtactt ttatcttcat aatcagaaag aggatgggac aaaaaatgaa cgcccaccct
    43681 cttctttttt ctctttcctt ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga
    43741 aaactatttt gttctctcct tcttcctgat agaatggatg ggaaaggagc ttgatgccat
    43801 gacaacgaaa gacaaggtac ttcaattatt gaaaaagaca ccagattttc tttccggaga
    43861 aaagttggca cagcaactgg aagtttcccg gacaagtatt tggaaagcca tcaaagaatt
    43921 ggaaaaggca ggctatcgtt ttgagcacgg gcctacaggg tatcgttacc tgccctctga
    43981 cgtactagat gcaaaagaaa tccagcaaga gctacggtcg tttattcctg atttgaaagt
    44041 acaaacgatg ttgacttctg aatctacgat gaaagatgcc aaactggcag cagctcaagg
    44101 agattctgtt tcgaagttat ttgttgctga tacacaagaa caagctcgtg gacgttttgg
    44161 acggcctttt ttcgctgaac ctggacgagg aatctacatg agtctcttgc tccatccaga
    44221 caaacggttt gatgaattgc ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc
    44281 cattgaatct gtaaccggtc gttctgcttc gatcaaatgg gtcaatgata tctacatgga
    44341 tggaaaaaaa gtctgtggga ttttatctga agcagtcagt gatatggaaa gcggcaggat
    44401 cagtcatatc atcattggga tcgggcttaa tttttctgtt cctcaaaatc attttccagc
    44461 tgatctccaa gaaaaagcca tctctgtctt tcccgacgga caagctagtg tcacaaggaa
    44521 tcagctaatc agcaaaatct ggcaagaatt gttcacttat ctttctcacc cagaaaaagc
    44581 gttggacttc tataaagaaa aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa
    44641 aggaacgact tatgtcggtc ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca
    44701 aacaaatgaa cagaagatga gtttgtcttc tggcgaaatc agtctcacat ctatccgtac
    44761 gcaataatta tcagatttca caaaaggaca cctgatctca tacagtgtcc ttttttctga
    44821 attctcttca aaagactctc cttattctat cagctgacag tttctctatc ctctagaaaa
    44881 aggtattcta aaaatatcta taaagcatgg tacactttct ttaaatgaat caatgcaaaa
    44941 aacaagagag tcatcagttt acacgatcaa aagagatagc aggccgcttc ctttttcaat
    45001 cttatagata gaccatgggt aacgataaaa acaaaaaaga acttgcgact tattttgccg
    45061 taagttcttt tttagctagt gccttaatct cttaatccca acaaacgtct cgcatagatc
    45121 acctgaccag agtgcatagc agcatcatca ataatagaaa cgagacgcat tcctcgtgtg
    45181 actggtggtg tccagttctc gtcaattact tcatctagct cggaaggttc cagccttctt
    45241 aagtaagaaa tagcaaaatc agcagctcct cgcaagtatc ctagcagatc ttctatttga
    45301 ttagcttgga tctgctttgc ttgttccaga ctatgcttcc aatcttgttc gttatctgct
    45361 atcgtcatcg gaaaccggct ttcccagtct tgactatgcc aaattggaga agttcctgct
    45421 aaatcagcaa tctggaaatc taattctcga gcggtatgcc aagccagcca agtcattgat
    45481 ttgatctgcg gggctctatc ttccactgga aaacgattgg cctcctcaat agagacgcct
    45541 tcaaacaaac gttcaaaccg atcgtatgcc cgatccacac tctcgcatag catatctaaa
    45601 taatccattt attttcctcc tttttattta tcctacttac tttttcctaa ttctaggata
    45661 cctacttata tgttactaca cacccttatt ttttacactt taacagtcac catcatcaat
    45721 agtttggaga ttgaaagaaa aagatagtgt cgaactatca attgaacaag aagcaacaat
    45781 atgaacgttt cattaatatt ctttaaataa acaatgattt ttcaaacgaa cagtttaaga
    45841 ctaggagaaa aagagtataa taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa
    45901 aaaagggcaa gtttactagt cctagttgct ttgttgttca atatcttttc gtatggtgtg
    45961 gccgtttcag cggaaacata cattcctaaa gaccctggga atatttataa tgatctaact
    46021 ggtaactatg gcttgttagg aattgctagt caattccacg tatttgctaa aaataagaca
    46081 actgtgaatg cacatacaga cggaaatata gcaacacatg aacttgatgc aaaaaataat
    46141 tttggtacag agcttcatga aggtttattg aaccaagaaa taaattatat acaaaaaact
    46201 gattctttcg ctaattcttc aggcatacct acaggtagca caagaatgaa taaatttgtc
    46261 gttggcagta acgtggatgt agcacttcaa gatggtcatc ctacagtcaa tggatccagg
    46321 cttgatcact taactccaga tgatttttat aaagatcgtg ctgggcatga atatattgat
    46381 ttcgagcagg aatttgctaa attgaatgta gcagcaaatg atcttgcaac gatcactcca
    46441 gctaaaacat atactgctgc agattttcca gacatgaaca atcggacaat cgatttaact
    46501 gatttatcag ataccgggtt tttattggta aatatcgatg cagaagtgtt aacgatgaat
    46561 acgccacttc aaatcattaa tccaaatgat caagtagttg tatttaatgt catcaacagt
    46621 tcttctgcat tgaacgtaca gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca
    46681 gaagattttt cggatgcgaa tatctcttgg aattttggaa atgagatgac tgatttgaca
    46741 atcagtgctc cttttcaagg aacaatcctt gcgcctaatg ctactatccg cattactcaa
    46801 aaccaagacg gaacgattat aggaacaaat gtgattttag atgcagctac caatcgttgg
    46861 gatcctaacg aaatatttat cagcgacaat ggtacagata cgacagacac aagcgacagt
    46921 acagatacat ctaccacaag tgatagctca gattcatca
//
LOCUS       DAFEEZ010000015        43258 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000015
VERSION     DAFEEZ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.015"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            214..498
                     /locus_tag="LP245_000941"
     CDS             214..498
                     /locus_tag="LP245_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBL1518875.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(779..1198)
                     /locus_tag="LP245_000942"
     CDS             complement(779..1198)
                     /locus_tag="LP245_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBL1518876.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(1200..1784)
                     /locus_tag="LP245_000943"
     CDS             complement(1200..1784)
                     /locus_tag="LP245_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBL1518877.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="LP245_000944"
     CDS             complement(1831..3306)
                     /locus_tag="LP245_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBL1518878.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="LP245_000945"
     CDS             3487..3798
                     /locus_tag="LP245_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518879.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="LP245_000946"
     CDS             complement(3913..6249)
                     /locus_tag="LP245_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1518880.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="LP245_000947"
     CDS             6391..7059
                     /locus_tag="LP245_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1518881.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="LP245_000948"
     CDS             7062..8105
                     /locus_tag="LP245_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1518882.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="LP245_000949"
     CDS             complement(8342..9223)
                     /locus_tag="LP245_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1518883.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="LP245_000950"
     CDS             9382..10110
                     /locus_tag="LP245_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBL1518884.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="LP245_000951"
     CDS             10266..10583
                     /locus_tag="LP245_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1518885.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="LP245_000952"
     CDS             10576..11184
                     /locus_tag="LP245_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBL1518886.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11239..12030
                     /locus_tag="LP245_000953"
     CDS             11239..12030
                     /locus_tag="LP245_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBL1518887.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            12168..12656
                     /locus_tag="LP245_000954"
     CDS             12168..12656
                     /locus_tag="LP245_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBL1518888.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            12707..13579
                     /locus_tag="LP245_000955"
     CDS             12707..13579
                     /locus_tag="LP245_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBL1518889.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13755..14117
                     /locus_tag="LP245_000956"
     CDS             13755..14117
                     /locus_tag="LP245_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL1518890.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14126..14878
                     /locus_tag="LP245_000957"
     CDS             14126..14878
                     /locus_tag="LP245_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518891.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDVGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14892..16694
                     /locus_tag="LP245_000958"
     CDS             14892..16694
                     /locus_tag="LP245_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518892.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16971..18011
                     /locus_tag="LP245_000959"
     CDS             16971..18011
                     /locus_tag="LP245_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL1518893.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18063..20207)
                     /locus_tag="LP245_000960"
     CDS             complement(18063..20207)
                     /locus_tag="LP245_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL1518894.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(20564..21937)
                     /locus_tag="LP245_000961"
     CDS             complement(20564..21937)
                     /locus_tag="LP245_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1518895.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="LP245_000962"
     CDS             complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="LP245_000962"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBL1518896.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="LP245_000963"
     CDS             complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="LP245_000963"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBL1518897.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23385..24398)
                     /locus_tag="LP245_000964"
     CDS             complement(23385..24398)
                     /locus_tag="LP245_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL1518898.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24479..25078)
                     /locus_tag="LP245_000965"
     CDS             complement(24479..25078)
                     /locus_tag="LP245_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1518899.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            25264..25965
                     /locus_tag="LP245_000966"
     CDS             25264..25965
                     /locus_tag="LP245_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518900.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            25975..28686
                     /locus_tag="LP245_000967"
     CDS             25975..28686
                     /locus_tag="LP245_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518901.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEGL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVREISTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            29137..30765
                     /gene="treC"
                     /locus_tag="LP245_000968"
     CDS             29137..30765
                     /gene="treC"
                     /locus_tag="LP245_000968"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBL1518902.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(30825..32006)
                     /locus_tag="LP245_000969"
     CDS             complement(30825..32006)
                     /locus_tag="LP245_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1518903.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            32258..33781
                     /locus_tag="LP245_000970"
     CDS             32258..33781
                     /locus_tag="LP245_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBL1518904.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(33850..34578)
                     /locus_tag="LP245_000971"
     CDS             complement(33850..34578)
                     /locus_tag="LP245_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1518905.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(34591..35871)
                     /locus_tag="LP245_000972"
     CDS             complement(34591..35871)
                     /locus_tag="LP245_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL1518906.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(36012..36614)
                     /locus_tag="LP245_000973"
     CDS             complement(36012..36614)
                     /locus_tag="LP245_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBL1518907.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            36859..37065
                     /locus_tag="LP245_000974"
     CDS             36859..37065
                     /locus_tag="LP245_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518908.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            37377..38096
                     /locus_tag="LP245_000975"
     CDS             37377..38096
                     /locus_tag="LP245_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL1518909.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(38177..38860)
                     /locus_tag="LP245_000976"
     CDS             complement(38177..38860)
                     /locus_tag="LP245_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBL1518910.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            39078..41264
                     /locus_tag="LP245_000977"
     CDS             39078..41264
                     /locus_tag="LP245_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBL1518911.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            41610..42020
                     /gene="spx"
                     /locus_tag="LP245_000978"
     CDS             41610..42020
                     /gene="spx"
                     /locus_tag="LP245_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBL1518912.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            42034..42390
                     /locus_tag="LP245_000979"
     CDS             42034..42390
                     /locus_tag="LP245_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBL1518913.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            43063..>43258
                     /locus_tag="LP245_000980"
     rRNA            43063..>43258
                     /locus_tag="LP245_000980"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT        14102 a         7621 c         8659 g        12876 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttcttt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag cgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa aattaaaaaa
    12661 gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga gagaaaaaag
    12721 agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag ctttagttgg
    12781 attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt ttttaagtat
    12841 ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca gtcctaatca
    12901 agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa atggcttttt
    12961 ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga atttcaatag
    13021 ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag cagtagtagt
    13081 ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc aagattttgt
    13141 agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt atgatacatt
    13201 caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg agttgcaaaa
    13261 agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac gcttgaacca
    13321 tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag caaaagccat
    13381 tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa tggccttaga
    13441 gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc aattgatcaa
    13501 taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca atacaggcga
    13561 catgaaagac cgtaagtgac atactttttg taagatagga agaaggagtt taggacggat
    13621 tattgtcttg aactcttttt ttagttgttt taaagaaaat gacaaaattg aaagaagaat
    13681 gatagttgat tcgaaggcag aattgttcgc ttttttctat aatcagtata taaagtaaga
    13741 gagaagggga aaaagtgaaa aaacttctga tcggtctact tgttttcatc gttgtggtac
    13801 ttgcaggggt gaaaatcgca gattacgtag ttatgggtgg agaagaatac tatgtacaaa
    13861 ttacgacaga tggtacaaaa acagtttcaa aatcagactc tggacaagaa acagtcaact
    13921 atagatatat cctgcctggc tatacgaaag agggtaagga aaaagaactg gacttcaagg
    13981 gacaattgac tcgaccgctt cgtaaaggag catatttaaa aatcacctgg aacaaaaata
    14041 aaggtgtcac ttcgtatgaa gaagtcgaaa aaaaagacgt gccgaaaaca gcactggaaa
    14101 aactaattaa agggtaggga aagaaatgaa caaaatagtc gaagtacaga atgtaacaaa
    14161 agtatacgga aaaaacaatg agaaaaagac gcaagcatta agcggcatca gcttcgatgt
    14221 agaaaaaggc gaatttattg ggatcatggg cgcttctggt tctggtaagt cgacactttt
    14281 gaatatttta tccacattag ataaaccaac agatgggcat atccgaatca atcaaaaaga
    14341 tgtgaccaca ttaaaaggaa atcaactagc agattttcgt gcgaatgaga ttggctttat
    14401 tttccaagat ttcaatttat tagaaagctt gacagcacaa gaaaatatcg ctgttcctct
    14461 ttctttacaa ggcgtcagac caaaagaaat caagcaacgt gtccaaaaaa ttgcagaacg
    14521 tttatccatc tctcatattt tggaaagcta tccttctgag atttccggtg gacaaaaaca
    14581 acgggtcgcc gccgcacgtg cattgatcac acaaccaacg attctattag gggatgagcc
    14641 tacaggtgcg ctggattcca aaagtgcccg ggatctttta gatacgatgg acgaattgaa
    14701 tacaaaagat catgtatcga ttcttcttgt gacgcatgat ccgttttctg caagttattg
    14761 ccaacgtatt ttattcatca aggatgtcgg tatccatcaa gaagtgaaac gtggagatca
    14821 aagccgtgat tccttctatc gagaaatact atctattctt ggaaacttgg aacagtaggg
    14881 ggagattgac tatgctttgg aaattatcac ttactgggat caagagccgt ttaagagact
    14941 acttggtgtt attctcagga ttagttatgg catctgctat tttttacatg tttgaatcaa
    15001 tggcaagcaa cgaagctttt ttgaaaagta atacgatcgt tgcggctaca gttatcattt
    15061 tccgattcgg ttctgtttta ctagggatca tcacattcgt ttatatttta tatgcaaatt
    15121 cctttttgat gacgatgcgg caaaaagact atgcaatgtt tatgatgctg ggagcaaaag
    15181 gcagaaaaat cgcacagatg attttttctg aaacattctt agtagggatc gcagctactt
    15241 tagtgggttc agctgtcggt gtaggattga caagtatcgt ccaccgatta ttagtggatc
    15301 agttagatct caatatttcg cattttacac cttttagtat tcacgggttg ttgatcactg
    15361 ttttgttttt tgctgttttg tttttattag ctgctgttgt caatgctttt tcgattgtca
    15421 aaaaaccgat tttagcattg attcgtgcgg atcagacacc aacaagaatc aagcagcata
    15481 aattcttgtt tttccttgaa gtagtactgg gaattgcttt tctaggctgc ggttactata
    15541 tgatgaaaca cgtggggacc tatcaagtct ttggtatagg ggtagcctta gttacgatcg
    15601 tattaggaac ttatttcatt ttccattctg tgatcatttt ctttttatca ttactaaaga
    15661 aatcagaaca gatttcattg aaaaaattga acaatttcac attgtcacag ttaaactttc
    15721 gtattcgtga atatacacaa atgctctcaa tggtcgctat gctgtttgcc ttggcactgg
    15781 gcgctttgac ggtaggatta ggttttaaaa atgaaattgc agacttgaca gaaaacaatt
    15841 ctggatatga tctagtgatg aataatcctc gggcagaaga tcagcaaaaa atcaaagaac
    15901 tttcaccaac actttctgct tcttatactc aaaaagaaga tgcgggaacg atttactata
    15961 atgcaagtga atttgcggct caaccattga tcatgataaa acatgaagat ggaacaccgc
    16021 cgaagatcac gaaagaaaaa gttcctgcta aaaaaatgaa tgaactgact gtacaagagg
    16081 aacttcgaag ctatgaattg ccggaacagc aagaaaaaga aatcaaggta gtcagtcaat
    16141 cagaatttga tcaactgaac ttgccacaat ccactttaca gctagttcag gtaaaagact
    16201 tccaagcaaa cctgaaacca atcgaaacac ttgttgctca aaataaaatg aacaatccat
    16261 ctttgcaaaa agtagagtac agcaaccaga aatatgaaat gtatgaagtg tataatggtc
    16321 tattctctgg ttttgaattt atgggattct tcctaggttt agctttcttg accatgcttg
    16381 ctagctgttt gatgttcaag atcttgtcag gaagcaagag tgacattgct cgttatgaaa
    16441 tgcttgaaaa gataggaaca cgacgcgggt tgcttaaaca atcgatccgt agagaagtag
    16501 gcgtgttatt cttagcacca ggaatcttag gtgtagtcca tgtcttattc ggattacaaa
    16561 tgtttggtct attcatgcaa aatccataca aagatatttg ggttccgttt acgatattct
    16621 tcgtattgta tttcatctac tatgtactga cgacatggtt atatactgga atcgtattga
    16681 aaaagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa gcaaaaatag
    16741 ctcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    16801 ttgttcggaa aaagaggttg tgacaatatt tttgtcacaa cctttttttc acggtctttt
    16861 attagaatat agtaaatttt ttctcgttac tcacggaata agctgttaag aaaacggttt
    16921 ccatgtatac tggaatcagt gcaaatgaaa gaaaagaggg tgcaaggaac atggaaatca
    16981 atgaacaaaa ttttggcgaa aactatcact tgattacgat cacgaatcaa aatgggacat
    17041 ctttgtctgt cagtgatctt ggggcacggg ttgttcattt tcaaacaata atcgataatg
    17101 aaaaacgaga gttgatctta ggttttgatg aagcaaaaga atatctagaa aaagaccctt
    17161 atatcggtgc ttcaatcgga cgtatggctg gacggattac gaatggcaca ttcaaattag
    17221 atgatgaaac gttcgaagta aaaacagacc cggacactgg tcattgttta catggtggtg
    17281 cacctagctt tgaagccaag cagtggcatt atacagtcat caatggtgaa aacgaagcat
    17341 cggtcatttt ctatcagact agcccagata tggaaaacgg atttcctgga actttagatg
    17401 tagaagtacg gtatacgctg acgaacgatg atacatggcg agtgacggtc caagggatca
    17461 gtgaccgcaa aacagtattc aatcctacaa atcatgtcta tttcaattta accggtgatc
    17521 cagcacagtc aatcgacgaa catatacttt ggttgaatag ccgattattt gctacgctca
    17581 ataaagatac aacgcctaca ggagaagtag tttcagtaag tggcacagca tttgacttcc
    17641 aacgtcctaa aaaattaggt gaggtctttg ccagtgattt tcgccaatca atgatagtgg
    17701 gcggcatcga tcatccattt ttgttgaaaa aacaatctgg tttactaaat gctgcggaat
    17761 tgacaagccc agatgaaaaa gtatcgatcc aagtaaaaac agatgcttca ggaatcgtga
    17821 tttttacagc aaattttgga gaagatggac cggaaatgcg cgggaataaa ttagtaaatc
    17881 atggcggtat cacatttgag actcaagaac tgccaggagc ggagcgactt gaaagttttg
    17941 gagatgtcac tctggaacct aaccaagtac gcgagtttgt aacggaatac aaaataaata
    18001 taaagaaata gaataaatta aaaagggagt gtgacagtgt cacatcccct ttttaattta
    18061 ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaacttaa caaggttagt
    18121 acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg tcttgccgta
    18181 aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc gttgttgacg
    18241 cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt ccatttgatt
    18301 ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc agttgttgct
    18361 gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat cgcgttcaat
    18421 ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt tgcttctttg
    18481 tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc agtcagtcca
    18541 tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata tttacggaat
    18601 tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt gaaggtcacg
    18661 ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc gcttgataat
    18721 aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga tgcgtagatt
    18781 ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa ctgatcagtt
    18841 gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga tgagccgcct
    18901 gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc aaaatcaggc
    18961 gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc atggataaat
    19021 tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg tccccagaag
    19081 acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata ttgctgttcg
    19141 cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata agtcaaacca
    19201 gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc aagatgcttg
    19261 aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa tacagcatca
    19321 attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat accgctttga
    19381 tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga accattgttt
    19441 ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg gtttgtttga
    19501 ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt tgaaccatta
    19561 ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg tgtactaggg
    19621 acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc tttaaattct
    19681 gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata atttacttct
    19741 ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt aatagtgtaa
    19801 gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat atccaaaggt
    19861 tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat caaagaagga
    19921 gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc agccggatca
    19981 atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg gtcttctgta
    20041 aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt tgtgactgtt
    20101 tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac agacggagca
    20161 atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat aaactagtcc
    20221 ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt tggaacagat
    20281 aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa ataaaacaat
    20341 ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta ttgcatagac
    20401 cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg taaattatac
    20461 caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa gaaaaagact
    20521 gaaatatgtg ataaacatct catacttcag tctttttcat taactattca taagacatta
    20581 ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga ctaacagcca
    20641 gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg gtcagactac
    20701 caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca ccagcagctg
    20761 caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg taaacagttg
    20821 gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc gaacgggttt
    20881 ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca aaattggctg
    20941 ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg atcatgacag
    21001 ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca gcgatgattg
    21061 cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct aaaccttcgc
    21121 caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg ataactaatg
    21181 aaagtaaagg tacaaatact aattgcatat tttcgcgaat atattttttg aggaattttt
    21241 caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac gtatactgca
    21301 tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct gaaagtaaag
    21361 aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat ccattcactt
    21421 taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag acggcattcg
    21481 acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca atcgtagtcg
    21541 ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg atcggcgtaa
    21601 agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct ttcggagctg
    21661 aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga tccatgatta
    21721 tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc tgttttaatt
    21781 tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc gcacatggaa
    21841 ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga atctgctcgg
    21901 acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc cactcactaa
    21961 tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac agttattcaa
    22021 ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta acaataattt
    22081 gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt caatcgattg
    22141 tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa gaccgtttga
    22201 gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat ccccgatact
    22261 taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat tgattacttt
    22321 tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg attgttctaa
    22381 agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa cagaagaggc
    22441 tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa gtgtgctgct
    22501 taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca ctttaaaagc
    22561 agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc ctagtgtaat
    22621 gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca aactgttatg
    22681 atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta taatgatatc
    22741 tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat tcaggatcgt
    22801 tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta agctactttc
    22861 aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta ggacttcttg
    22921 ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc ctgctgcgtc
    22981 taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc cagatgtatc
    23041 gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag ccccaacgcc
    23101 tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt tggcaccttt
    23161 acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct tgggcatgtt
    23221 ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg tgttcatttt
    23281 acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa acgttttagt
    23341 aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt caagggtgca
    23401 gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc tttttctggg
    23461 aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa gattggttgt
    23521 gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc atagccaata
    23581 atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata taatccaaaa
    23641 gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag ttctgctgtg
    23701 atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg gtcgtgaggg
    23761 atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac attttccggt
    23821 ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa gtgcatgccc
    23881 gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc ttcagatttt
    23941 ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt gattgcatct
    24001 gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt gagctcggct
    24061 agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt gacgaaattc
    24121 tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg attcgtgata
    24181 tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct agcaaaatag
    24241 tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt tttcggactg
    24301 aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac gccggaaagt
    24361 ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct atctaaatcc
    24421 tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt
    24481 atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt gcagttttcg
    24541 gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg caagcatctt
    24601 cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca tatacaccgt
    24661 ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga agttgaagat
    24721 caagagaagt accaaaaaaa gcacttggat tgtattttgt gatagtcaac atattatctg
    24781 tatctttcaa agaatccttc aaaagtaaat cagtgaattc tggaggtaca gaagcagtca
    24841 ttccacccat atcagtttgt tgactcaaat aagggaaagt ggagatgtct acgttcacta
    24901 aaactttcaa ggcagcggta cgtttcaatg ttcttactaa caaatcattg tttgtcagaa
    24961 tagatgctgc agtgtgtgga gagagtgtac cgttatttac gatctctttt tgcatgtcga
    25021 tcgcgacaaa agcagttttt gataaatcaa aaatcatatt ttcctttaaa tcattcatga
    25081 tgttccttct ttcaaataac aatgtttttt atgtaagtaa atcataaatc gtttatttgt
    25141 caactaaatt aaaggattcc tttctttagt ctagagaaat tcagtggtaa aataaataag
    25201 tgtgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa tggaggaatc
    25261 agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg agaaacgacc
    25321 attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt gattatactt
    25381 ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat ggatacacct
    25441 gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga taaacagctt
    25501 actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct cgttcctaat
    25561 ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc gcttgatcct
    25621 gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc gtcccaatta
    25681 tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa tcccaaactt
    25741 cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca agtattgaaa
    25801 ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac acataattct
    25861 gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt aaggtctgtt
    25921 gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga ttttatgaaa
    25981 acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg acgattcatt
    26041 gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa aactgctgga
    26101 cctgtcatgc aaaaaacgat ggatcactat gttggtacag caggactttc tgatttgcaa
    26161 atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa gatcccagat
    26221 gcaaaagtag aaacaggaaa acagatctat tattccaata ctggcaaaaa cgaagtgatt
    26281 caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac tgatggaaaa
    26341 ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga agggtataaa
    26401 atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta taccatcacg
    26461 ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc gaacgtcgga
    26521 aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac agatatttat
    26581 tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag caaagcttac
    26641 aaagataaaa tggagcaaaa tcaagaaaag gcagaaaagt atttacaaga tcgacccgaa
    26701 gaacgcttag aagagctgaa aaaatcggcc aacgaagaat tagaaccggc acagcaaaaa
    26761 atagcggatg gcaaagcaca aacaacgcaa gcaagaacac ggttagaaga tgctaaaaaa
    26821 cagttagcgc aacagtcagc aactatccag cagcttcctg aagcgcaacg aacaatcgct
    26881 gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca attagttgag
    26941 aaagaacgtg aactggcctc tgcagaggaa ggattgaatc gaaatgcaga aaaaattgaa
    27001 aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg ttttcaagaa
    27061 tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt tttctttttc
    27121 tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga aaaccgcagg
    27181 gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa aaaatatgca
    27241 atctatgcaa gtctagcctc agggataggt attgttttag gaacgatatt aggaacgaat
    27301 cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg gagtgcgctt
    27361 attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat tgccgcattt
    27421 ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc attgcttcaa
    27481 ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc gctgtggtca
    27541 cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa gtcaagaatg
    27601 cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg cgtgggattg
    27661 aaagattctc taagttctgt ttcagccaaa caatttggac cgatcattga ctatcaagca
    27721 atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga tatgctgcag
    27781 aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga attgagaaaa
    27841 aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc tgatttggat
    27901 cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa aacaggaatc
    27961 gctattacgc aaaaagtagc agaactattt gacttatcta caggagatca tatttcgctt
    28021 tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa aaactatcta
    28081 ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca atcgatgatg
    28141 gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga aatgctttcc
    28201 gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa acaaatcgaa
    28261 acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt cgtattatca
    28321 ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc cgagcgtgta
    28381 cgcgaaatat ctacaataaa agtccttgga ttttttgata aagaagtcac gatgtacatt
    28441 gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg tgtaggatat
    28501 atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt tccattagtg
    28561 atcacatggt gggcttatgt cttatcagca ggattaacta tcgtatttac ggttattgtg
    28621 atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt gaaatcgaat
    28681 gaataaaaac agaggttgtg aaatcagcgg tttgacctga gtattagaga aacaaacggc
    28741 aaaatagttt ttcatatttt gccgtttttt gagctaatac cgaaggacag ctgattgaac
    28801 accatgaatc agaggttgta aaaaagccgt cctgcatcga gcaaaaagaa tactcaaata
    28861 aaattagctc ctcatgtttt acatttgaga agactgattg ccgtagataa aagcttttga
    28921 acaccattta tagaagaaac aagaatattt tgctatttta aacaagagga tagacaaata
    28981 catgtctgat ctcttgtttt ttattgggca acagacctct tagaatgtat aaagataaat
    29041 tttacaaacg ctttcggttc agttataata ataaatgata acttgtatat ataagttgtg
    29101 gtaggtaata aatcagttga atggaggtaa atatccatga catttaaaga caaagtcatt
    29161 taccaaatct atcccaaatc ttacaaagac agtaatggtg atggaattgg agatttaaaa
    29221 ggaatcaaag aaaaactccc gtatctgaat gatctaggca tcgacatgat ttggctaaac
    29281 cctatttatc caagccctca aaaagacaac ggttatgata tctctgatta cacagccatc
    29341 gatcctatct ttggtacgat ggaggaattc gaacagctaa tagccgaagc aaagaaatac
    29401 cggatagaaa tcatgctcga tatggtgctg aatcacgttt cgacagaaca tgaatggttc
    29461 aaaaaagcac tagcagggga ccagcattat caggacttct tcattttaag agaagagcca
    29521 acggattggg tatcaaaatt tggtggaagt gcttggtcgc catttggaga tacggggaaa
    29581 tattatttgc acttatatga tcggacacaa gctgacttga actggcggaa ccaagcagta
    29641 agagaggaac tattcaaagt tgttcgtttt tggatggaaa aaggggtaaa aggattccgt
    29701 ttcgatgtta tcaatgttat cggtaaagac gaacaattga aaaataataa agaaaatgat
    29761 ggcaaacctg aatatacgga caaaccaatc acccatacgt atctaaaaga attgaaccaa
    29821 gcaacgtttg ggacggattc cactatcatc acagtcggtg aaatgagctc tacgacgatc
    29881 gaaaattgta tcttgtatac agaacctagt agagaagaat tatcaatggt ctttaatttc
    29941 catcatttga aagtcgatta tgaaaatggg aataaatggt ctactcctcc atttgatttt
    30001 gcagaattaa agcgactatt tcatacatgg ggagaaaaga tgagtgaggg taacggctgg
    30061 aatgctctat tttttaataa tcatgatcag ccacgtgcgc tcaatcgatt tgtagctatc
    30121 gatcagtatc gaaaacaagg agcagagatg ctagcaacca tgatccattt gaaccgtggg
    30181 acgccctata tttatatggg agaagaaatc ggcatgatcg acccagacta ttcatcgatt
    30241 tccgactata ttgacgtaga aagtttgaat gcttataagt tactccttga acaaggattc
    30301 acagaaaaag aagcgtttcg tcggatcaaa gcaaaatctc gcgataactc tcgaacaccc
    30361 atgcaatggt cagacacaga acaagcagga tttactacag ggaaaccttg gttaaaagtt
    30421 ggaggcaagc tagaagagat taatgtagaa aaagaactat cttctgaaga ttctattttg
    30481 tcctattaca agaaattgat tcggctgaga aaaacatatc caatcgttgc acaaggagat
    30541 tatcatgctt atgaagcaaa tcatccggaa gtttatggct ttcttcgcca atttgaagga
    30601 cagcagctgc ttgtattaac aaatttctat gataaagata caaggatcgc catcccagaa
    30661 ggattcacag aagccaatat tcttatcgat aattattccg atactgttct tcatcaaagt
    30721 ctggagctaa aaccatacca ggcaattgct ttgctgaaaa attaaaacaa aaacacaaaa
    30781 cgtcgttcct acgagctatt ctcgtaagat cgacgttttg tgttttattt aaaataatct
    30841 tcttcagaaa atgaagagtt ttcatactct cctttatcgc cataaaattt attgtagcgt
    30901 tgtttgaatt tacggaaaat aaaagtaacg agtaatttga ctaacgtata gataggaata
    30961 ccaaaaataa cgcccacaat tcccattaga tcacccatga caagtaaaac gattaagatc
    31021 gtaatcggat ggatctgtaa acgatcaccc attactcgag gaatcaccaa gtcaccgtgg
    31081 agaagttgta cggcaaacca gacaatgaca aatttgacag ccataaaagt agagtcttgg
    31141 aatgcaatga tcaaacctgg aaagaaggcg ataaacggcc caatatatgg aatgatacat
    31201 aacaacccag cagaaatagc taaaacacta gcaaattcta atccgatcag taagaaacaa
    31261 acccagtaga ctgctccaag gataaatgaa gcaatgattt gcccctttag aaatgaaccc
    31321 aattgttgat tagcaatctt tgtcaaattt ttaaaatctg tacgaaatgc tggtgggaca
    31381 atcgctaaaa ctgactgata aaatttttga ggatctctca aaaggaaaaa agcgacaatt
    31441 ggaccagtaa ataaagtaat aaaaatagct gtaacagttg aaaaaatgtt gctgatccgt
    31501 tgtgcgccac tttcccaata atttccaata aatccagcta tatcagacgt cacgtcgtca
    31561 atagaagcga aaaattgatt aaatgaatcg gcaaaaggtg ttttctccaa aaattgtcgg
    31621 agactctctt gaaaatcttg aaacaaatct ggcaaactac tgatcaatgt ctttgcctgt
    31681 tcttcaagaa aaggaataag ccatatgctt ccaagcccca ataaaaataa aataatcaca
    31741 taaacgataa tgactgacaa gttcctcgaa aggtgcttgc tcaaacgttt gatgactggt
    31801 tccaaaagat aatacaagat cagtgcaaac aataatgggg gcaagatagt agcgataatg
    31861 attccgacag gcttgaatat aaacgagatc tgatggaaaa aataaatgat cagcgcaagt
    31921 aagataacta ttcctaaaac atagtaagag gtttttcctc ctaaaaagcg gatcaaacga
    31981 ttcgttgtat ctgtttcttt tttcactctt tttcctcctt tatctataaa ttcattatag
    32041 acaaaagcgg gtataaaagg aaaatgatag aggttgattg caaaaatatc gtcaatcatt
    32101 catataaact ttctcatcaa ttaaaataag aaaacgcttg acagttcttt taaccatatg
    32161 ataaattaaa tcctgttgct aaaacgtaac tattacggtt tgcgaaaagc gaatcggaac
    32221 attcaaatga aagaagatga gaagaggagt gtcataaatg aaacgattga taggtatatt
    32281 ggccatgctg gttttagcag gtatgttaac tgcttgcggg gcaagtggga aagccgagga
    32341 cagtaaagaa aaattgagcg tgatgacgac cttttatccc atgtatgatt ttacaaaagc
    32401 aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg attcccacga
    32461 ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct ttgtttataa
    32521 tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag aaggcaatgt
    32581 ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag aaggacatga
    32641 tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac atgtatggct
    32701 agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga ttgaagctta
    32761 cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga aacttcaagc
    32821 actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt ttgtcacgca
    32881 acatgctgca ttcaactatc tagcgttaga atatggattg aatcaagtat cgattgctgg
    32941 tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac actttgttaa
    33001 agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta ttgccagaac
    33061 gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag gattgacgaa
    33121 tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc tcgaagcgtt
    33181 gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca aaaaagaaaa
    33241 gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc tttcagattg
    33301 ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg atcctgtttt
    33361 tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag aatattatac
    33421 gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga tggcatttac
    33481 gtttaagaat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag aaatcttgac
    33541 ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata aggaaagtgg
    33601 cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact ccgaacattt
    33661 tcatttatat gcaggaaatg aaagtcaaga agtattgctg aaagaaatgg agaattggcc
    33721 aacattttat ccagatacaa tggatggacg tgaaattgca caggaaatgc ttttgcactg
    33781 ataggcaaaa aagaaccgaa gggtttggat cggctggtca tttagtcggt ccaaactatt
    33841 cggttctttt tatgaaatca atttctttaa tccacggata gaggctggga tggtctcgcc
    33901 gtttgccaac gtgacttctc tggttttttt attaatcgac cgcacatttt gtgtattgat
    33961 aacataggat ttatgacaac ggataaaatt ccgatgcatt ttctcgattt ctttgatctt
    34021 ctcatagaat tgtaattggg catgagtcaa atggacttcc agtttatgtg gcgctcctag
    34081 cgaagtagaa aaatattgga tgtctttgat cggtaaaaat ttgatctcat cattaaactc
    34141 tattttgaag atatcttttt ggatttggga catttgaaaa tcttcgaaaa ttttgctcag
    34201 gatatgctcg acattttctt ttaaatcata aagatcttct ttgacgatat aatcagtcgg
    34261 ttcgatgttg ctttttaaga ttttcatcga catttccgta tgggaagtca catagattat
    34321 ttttcctaaa ggatctaatt cacggatcaa tttaccgatc gctacaccat ccatttcact
    34381 gtcttctagt tcgatatcta aaaagtaaat accaaaagaa gaagttctga tcttggctgc
    34441 attgagaagt tcttccggat cagaggtaga aatatggaca taactgtcta agttttcaat
    34501 catgattcta tttttgatca ccgttgataa aacttctaat tgttttggat cgtcttcaca
    34561 aatataaatg ggaatcatat cattactcct ttattttatt tgtatataaa tcgtttgaga
    34621 aaaacgctgg ttttcaattg atgtttcaag gaaaagataa ggattggtct ttgtcaattc
    34681 atccaagata aacaagccaa ggccttcgtt ttttggattt gtttttgttg agaacccttt
    34741 ttgtttcaac tggtttaacg gtaatgtatt tgttgttgta ttgatcacac gaatcatcac
    34801 ggaatgattc ttcttgagta tggtcaattc gatttttttc ttctttgcag cactagctcc
    34861 ttcaatcgca ttgtccaaga taataccaag catacgtaca aggtttaccg tatgtttcgt
    34921 atccagttcg attggctcag gaaaatgaag ctggacgatc aacccttttt cctgtgccat
    34981 catgagtttt aatgacagta aactacggat ctcaggaact ttcatattat ccaacatact
    35041 tagattggcc ggaaaaaggt tcatcatctg gcgtgtaggt aatatcgttt gatcataata
    35101 agaccgtaat ccttctaagt cgccttctga aatatagctg tgaagagaaa aaagcagatt
    35161 ttggtaatca tgtttgaatt ctctcaagtc ttgatagttt ttttctagat ctttgatata
    35221 atcctgttgc atcctgactt gttgctctaa taactgatca gctaatttct tattagagat
    35281 tttccaataa taaaccaaga tgatcaggcc aacacacaga tatagaatga aaaaactcgt
    35341 attcaaagct aagacatcag gtgtttcacc agaaaaacgg gtataaaaaa taatgatata
    35401 gtatgtaaat aatatcaatg tcccgatcgt accgatcata cggcggtcca cagtgtgaaa
    35461 ccaagtctct aacgattttt ttaaacaaaa agctaataaa gcagataaaa aagcggataa
    35521 gacaatgtga aaatactgca atgaatctcc tggttcaata accgaagatt tcaaaacaaa
    35581 aaaatcgccg atgcttgtta agtgatctcc taaaagcgac gtcaataacc caaaaggaag
    35641 cgcgtaaacc aattgttgac gcgaagtcga aaagaagaaa aaagtaagca tcagcattcc
    35701 tatagcaatt agagcagtaa aaatccctaa aatcgaatag acccatccaa tcaaaataca
    35761 agaaatcaga atgactcccg caaacagata tttgtatcgg atgtgatggt caatcaataa
    35821 gatacaaatt gtgtaaatca aatattgcaa cgctatggac cataaaaaca taaagtacag
    35881 ctcccattga tttttaccaa attatagcac aattggcgta ttattttttt aatttttcag
    35941 ggattttgaa ttcagaactc ataccaaagc agcagccaga tacaaaaaag tcagataagt
    36001 tagttaattg tttaatgatt gtttttttca tgaaagattc ctccaaaatt catcaagtag
    36061 tttgtaatag gaagcaacgt agctatttct aaaacaatcc caagtagcaa ataggtagaa
    36121 aagtaagaag ctgagaaaaa taacgtaatg agagaaaaaa ttagaaacat gctgatcgcc
    36181 ttctttaata atgggggacg tttctcgggt tcaatgggat tgattgctgt acctcttgat
    36241 ccatagcgaa gcagtaacaa aaagcagctg attaacaaaa agaccatcat tgggaaggag
    36301 atagtcaatt gcagatgttt catcaccaag ggaacgcccc ataaataaag tagtgtccac
    36361 agcagacaaa cgaattcaga gtcggaatgc aatccataag catatctgcg gatgcagata
    36421 taagaaagaa aggtgattcc tgtttccgcc catgagcctg tcaccagaga aaagactaga
    36481 acgaccgcta gttttccaag attattcaat aaaacttcta agacaaattt tacttggaca
    36541 tacaccatat cttcttccga tttgtctccg ctgaataagg cttctaataa tttgttcaca
    36601 actttatctt tcatctcata cgtacctcca ccacaaattt tatgctaaaa aaaataaaaa
    36661 acgtcttttg tttcataaaa agtggttttg acatcaaaac cgtcatgatc tcctaaaaaa
    36721 atcttcgttt tccaagaacc ttaccaaaaa aagtgacagt tttgatacga aaagtacttt
    36781 ttatgacaag tttgtgcttt ttcgagtgat ttatgttaaa aaattactga ccttataaaa
    36841 ggtgatggag ggattcttat ggaaaatgaa caattgtttg aagtcggcga aacatatgca
    36901 tttaaatctg atttatttga atcaccaata aaaggaaaaa tagaaaaaat ctatgaaaat
    36961 agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca atgataccgc tcataatctg
    37021 cactggcagt tagttgtacg caaatcaagt acaatagaag aataaaaaca gataaaatgt
    37081 tgagagcata aagaggttgt gagtctcccg tttagctctg agttacaagg aataatgtta
    37141 aaaaacagct tttcatgttt tatgaatatt gccttgtgac cgaggtgttg gcaggagaat
    37201 actgtttatt tgaaaaaagg gctgcgacaa gacttttgtc acagccttta ttttcatgaa
    37261 taggagttac ttttggctac ttttagagaa gtagctttta aggagcagat aaagtcaagg
    37321 cttttatttc tataaatgaa gtagtaaaat gaagaacaga ttttattaca ggaaggatgc
    37381 cgataattgt gatcattgtt gcaggaacga tcggtgcagg gaaaagcaca ctaactgaaa
    37441 tgcttgccca agatttagaa acaaaacctt tttatgagaa cgtggaagat aatgaagtat
    37501 tgccgctatt ttattctaat ccagaaaagt atactttttt attacagatt ttctttttga
    37561 acaaacgctt tttggcaatc aaagatgctt tcagccatga tgacaacgta ctagaccgct
    37621 ccatctacga agatagtatg ctgtttcatt tgaatgcaga tttagggcgt gtttctgaag
    37681 tagaagtaaa gcagtatgaa ggtcttttag aaacgatgct gaaggagtta gaagaaattt
    37741 cgccacaaaa gaaaccagat ctactggttt atattcgtgt atcctttgaa actatgttag
    37801 cgagaatcaa aaaaagaggc cgggaatatg aacagctaga acaagatcct gaactctatt
    37861 cctactataa agaactcaat cgacgatacg aagagtggta tgaacagttt gatatatgtc
    37921 ccaaaatagt gatcgatggg gacaaatatg atttcgtagc cgatccggca tgtggagaac
    37981 aaatcgtaca agaaatcaag atgcgggcaa agaaaatgac agaagaggca gatgcccagt
    38041 cgatccgcta cactacaaat aacccgaaag caaagggaat ctttacaact aaataatata
    38101 aaaactaagc aaattgctca ctcgcagata tttctctgtg agcagcatct tgcttagttt
    38161 ttttgattca ttgagatcaa atagtgaacc gattcgtatg ataaaattgc cataaatgaa
    38221 atgtctgagt gagggccatg atcaaaaata aaatggaaac gatcaaaatc gaatgggcgc
    38281 caaacagatg atgacagaaa acaaggacaa tagctcctgc gataaaggca agaacgacac
    38341 ttagatagtg gaaaaatcga tcaaaatctg ctttttcttt agaaatacaa taatcatata
    38401 agttcgttgc tacccctttt aaatttccag ttgtaaataa attagtgtag gcacgcccgt
    38461 tgattttatc aaaagctacc cactggatcg atgcagtaaa agcaatcaaa atcgttacta
    38521 atgcgggatg ctcatggacg ggtgtcaaac taacaaagaa aaaaatcact gcttcataat
    38581 atagaacaaa caagcgccag aaatgttttt ctttttttct aaaataatca attagatact
    38641 ttgttagaag aatccctaag aaaaagaaaa gggtagacaa tactttttta ccaacactta
    38701 gccattctcc gtcaaatgct tggatgatcg atagaatgat attgccagtt tgagcagagg
    38761 caaaagcacc atattggata taagtataac tgtccatggc tcctccgata aatgtcagca
    38821 aaagtcctat tgtacgcccc tcgtgaaagg aagtctgcat ttttttcatc accttttatg
    38881 aatatttttg tcttccttat cttagcataa acgattgaaa aaaaggaaaa attttcagaa
    38941 aactaaaatc atatcgcttc ccattttcat ttttagaaag gtctgttagt ataaagaaaa
    39001 aatagacaac gaaactttaa ataaccaact tgaaataaac aaattcaaag aagaaagatg
    39061 ggaaggaaat caatcagttg aatgaaaaag aaattctccg attacaaaaa gaattgaaac
    39121 gctgggagaa caagtataaa aagcttcaac aagtctttcg gctacaagaa gaaatcattg
    39181 ctacctatga agcggcttat ggcgaagcac ccggacttat tgaggaagaa gtacaagtaa
    39241 aagaaagtga aggaaacagc tctttcttta aaatgatgga gaaacgttcc tataatcgct
    39301 tcaatcaaga acaaaaagca gctatcacat atgatatgaa gaaacatctt cgaatcatag
    39361 caggagctgg gagcggcaaa acgcaaacaa tctgtgcaaa agctgtttat ctgatgacgc
    39421 aaaaacaagt agacgaagaa cgcatactaa tgatcacttt tacaaggaac gctgcaaatg
    39481 aactaaaaaa acgagtagat aatttcagcc agagaaaaac cgctgtccat atcggaacat
    39541 tccatagtat cttttttagg atatacaatg aaatttgtcg aaaatttcct gaagtagcaa
    39601 tgcaaggaat acaaggagac ttttcaaagg atactgcaca aaaagtgaat gctgttttgc
    39661 aacagctgat acgtaaatat aatctttata tatttgatca atatggagaa aaaacgattg
    39721 cttctcggtt agactattgg cagaatatga acctttcagt agaagaaatg gttcagttag
    39781 ttaaagaaaa atatgattcc attgataaga atgcacgaca gccgatatca gaacgactgt
    39841 atggattgct cacggaactc caagaacaaa aaagaagcca gcaattgcta gagttcaatg
    39901 atgtactcca aaatctgaaa agcgctttgg agaatgagga gatccagcat tatatcggcc
    39961 aaaaatatga ttatctattc attgatgaat ttcaagatac taatccactt caatgggaaa
    40021 tcgtgaaacg gatgacaaag gaaaacagga tcaagttgat tgttgttgga gatgatgatc
    40081 agagtatcta tggattcaga ggatcagagc cagcatacat caagaacttt gaaaaagaat
    40141 atcctaccaa aactcttttc ttattaacta attatcgttc tcgggcagct attgtccaag
    40201 gagcaaatag attgatcagc tataataaaa atgatcggat accaaaggcg atgattccag
    40261 cacaaaaaga agcaggtgtt atggaagcct atttgttttc tgatactaaa gcagaaagtc
    40321 agtggctaat caaacaaatt cagacattta ttcaaaaaaa tgggaaatat aaggaatcaa
    40381 tcatattata ccgatcagct tcacaaacgc agcagcttgt ccaatctctg ctgaaaacga
    40441 atattccttt tgtactggaa gcagatagtc catatgaagg tatctttggt atcaagtctt
    40501 tccaacattt ctatcaaaaa attgttcatt ggcaaacagc actgaatctg caaaagaaaa
    40561 atcaggccta ccagcaattg ctccggcagc tgatggcaga ctgctacctg aaaaaaagtg
    40621 aatgcgatca atacttttct cctaaatatc aaaatatagc cgttgcagat tatattttgt
    40681 cgataagccc caatttaaaa tcgaaatctg cagaaatccg agagtttgag gaagcgttgc
    40741 gtaaaacaga ccagcatcaa gaaatctatt cgcttgttca aagctatctt catctgccac
    40801 gtatagctaa ggaaatcgac cagagtgatc aagaatggat acgagaagaa gtaaagcagc
    40861 atgctacttt cagaagactc caagccttat cgcaagaaac ccaagcgaca gctaaagaat
    40921 taaaaacccg cttgattgct tacagacaag gaaaacttga tgcactatgt atccagagca
    40981 ttcacaaaag taaaggtctt agttaccgaa atgtcttttt gattggttgt aacgaaggaa
    41041 gtttgcctta taacggagcg acagaaaaga aagtaatcga ctttaatgaa ataaaagcag
    41101 aaccagtaac gacgatagaa gaagaacgaa gactatttta tgttgcgatg actagagcaa
    41161 gaaatcgtct gtatctatgt gtacctcaaa tgaaaaattc aagaaaattg aaagtatcga
    41221 gatttatcaa agaaaccggg agtcgtgtga aaaaaggaaa gtgatagaag agagggtgtg
    41281 acagaagtgg tcagtttcaa gaaagaagaa ggaatgtacg aaaattgctt ctcaaatttt
    41341 tgtgaaattt cagcttattt tcgaagaagc tatttctgga acacagttta ttcggaaaag
    41401 ggaggtgtga caagaatttt gtcacacctc ccttatttat tttgaaaatg agaatactat
    41461 tatcaaaata gagaatatat agaaaaattc tcattattca aacgtaaata atcagttatt
    41521 ttgatttttt ttatatttta ttagctaata attggtattt taaaagaaat tactgtagaa
    41581 ttggattata attaaaaagg agtgagaaaa tgataaaagt atatacttcg cctagctgta
    41641 cttcctgtag aaaagcaaga gcatggttgc aagcgaatca acttgaattt gaagagaaga
    41701 atatttttgc cgaaccgtta acagaaagtg agatcaaaaa gatcttggca gcgactgaag
    41761 gaggagttca agatattatt tccactcggt cgaaaattta cgaaaagctg ggcatagatt
    41821 ttaacgaatt aactttaaag caaatgatcg tcttattcaa agaatatcct tcattattga
    41881 gacgacctat tttgattgat gaaaaaagaa tactaatcgg atttaatgaa gatgagatcc
    41941 ggtcatttgt ccctcgtgaa attcgatgtg ttgccagaaa tctgatctat ttacaaaaca
    42001 ataacatctt aaattcatag ggagggagcc ttcgtggaag tgaaagtcta tggatcagcg
    42061 cactgtgtaa caagtctgaa ggcgaaacaa tggttagaac accatcaatt gccttatcaa
    42121 tttgttgact tagaagaacg cgatctaagt acagaagaag cagaagaatt atgcagtttt
    42181 gaagaagtgc aagcagaaca gctatttgcg acttggtctg aggcttttca caacattgcg
    42241 attgaccttt cctgtgtagg aaaaaaacaa ctgatttttt tatgcacaca acataccaat
    42301 ctcctcagac gtcctttgat tattatcgat gaagttctat ttattggata caatgagcag
    42361 ttgatggaac agcttatctt aaataaatag actttaactg ttttaatcaa gtcactgagc
    42421 atttcataca gttgtaacag tcgaacactt agcatcaagc gtgttatgtg ttcttttttt
    42481 gactttattt ttctactata gagacatgct caatttatgt ggtcaaaatt caaatctagg
    42541 tggggatata gagttaaaaa tatattgaca tgtgtaaatt tacatgatat attcatttct
    42601 gttgttttaa gtagcaaagc aataaaatag tattttaaaa aacatataaa atagttgttg
    42661 acatgttaga aatgacatga taagataact gagttgttaa aaaagaacca cttgtgaagc
    42721 ttgattctat cgaaaaaaac ttcaaaaaag ttcttgacaa ataacaaatg ataagttatg
    42781 ataaatgagt tgctgtaaga tttcgaaaaa cgaaatcaaa aaaactttta aaaaagagtt
    42841 gacaattact tgtctctctg atatgatata aaagttgcta cggcagccaa aaacgaatcg
    42901 gggaacactc ctgatgaagt agacctttga aaactgaaca aagtaagaca aaccaaatgt
    42961 gtagggcgtc ttgattcaat tcaagacaac aaacattttt taacaagcaa gcaatatgct
    43021 agcaaacaaa ttgagcttaa caatcgcaag attgttcgaa ctttttatga gagtttgatc
    43081 ctggctcagg acgaacgctg gcggcgtgcc taatacatgc aagtcgaacg cttctttttc
    43141 caccggagct tgctccaccg gaaaaagagg agtggcgaac gggtgagtaa cacgtgggta
    43201 acctgcccat cagaagggga taacacttgg aaacaggtgc taataccgta taacaatc
//
LOCUS       DAFEEZ010000016        40827 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000016
VERSION     DAFEEZ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.016"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            34..657
                     /locus_tag="LP245_000981"
     CDS             34..657
                     /locus_tag="LP245_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518914.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1107..2156
                     /locus_tag="LP245_000982"
     CDS             1107..2156
                     /locus_tag="LP245_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1518915.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2153..3034
                     /locus_tag="LP245_000983"
     CDS             2153..3034
                     /locus_tag="LP245_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518916.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3037..3807
                     /locus_tag="LP245_000984"
     CDS             3037..3807
                     /locus_tag="LP245_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1518917.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4086..4940
                     /gene="aroE"
                     /locus_tag="LP245_000985"
     CDS             4086..4940
                     /gene="aroE"
                     /locus_tag="LP245_000985"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBL1518918.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5118..6281
                     /locus_tag="LP245_000986"
     CDS             5118..6281
                     /locus_tag="LP245_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL1518919.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6398..6808
                     /locus_tag="LP245_000987"
     CDS             6398..6808
                     /locus_tag="LP245_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1518920.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6982..9210
                     /gene="topB"
                     /locus_tag="LP245_000988"
     CDS             6982..9210
                     /gene="topB"
                     /locus_tag="LP245_000988"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL1518921.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9381..9665
                     /locus_tag="LP245_000989"
     CDS             9381..9665
                     /locus_tag="LP245_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518922.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9825..10061
                     /locus_tag="LP245_000990"
     CDS             9825..10061
                     /locus_tag="LP245_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1518923.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10058..10456
                     /locus_tag="LP245_000991"
     CDS             10058..10456
                     /locus_tag="LP245_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBL1518924.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11123..12067)
                     /locus_tag="LP245_000992"
     CDS             complement(11123..12067)
                     /locus_tag="LP245_000992"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBL1518925.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12363..13307)
                     /locus_tag="LP245_000993"
     CDS             complement(12363..13307)
                     /locus_tag="LP245_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1518926.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13528..14742
                     /locus_tag="LP245_000994"
     CDS             13528..14742
                     /locus_tag="LP245_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1518927.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14764..16779
                     /locus_tag="LP245_000995"
     CDS             14764..16779
                     /locus_tag="LP245_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBL1518928.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16862..18235)
                     /locus_tag="LP245_000996"
     CDS             complement(16862..18235)
                     /locus_tag="LP245_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBL1518929.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18261..18545)
                     /locus_tag="LP245_000997"
     CDS             complement(18261..18545)
                     /locus_tag="LP245_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1518930.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18547..20562)
                     /locus_tag="LP245_000998"
     CDS             complement(18547..20562)
                     /locus_tag="LP245_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL1518931.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20741..21046)
                     /locus_tag="LP245_000999"
     CDS             complement(20741..21046)
                     /locus_tag="LP245_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBL1518932.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21135..22166)
                     /locus_tag="LP245_001000"
     CDS             complement(21135..22166)
                     /locus_tag="LP245_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1518933.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22373..23248
                     /locus_tag="LP245_001001"
     CDS             22373..23248
                     /locus_tag="LP245_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1518934.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23400..24242)
                     /locus_tag="LP245_001002"
     CDS             complement(23400..24242)
                     /locus_tag="LP245_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1518935.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24334..26211)
                     /locus_tag="LP245_001003"
     CDS             complement(24334..26211)
                     /locus_tag="LP245_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL1518936.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLSDISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26208..27629)
                     /locus_tag="LP245_001004"
     CDS             complement(26208..27629)
                     /locus_tag="LP245_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL1518937.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27632..31021)
                     /locus_tag="LP245_001005"
     CDS             complement(27632..31021)
                     /locus_tag="LP245_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL1518938.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31278..32669
                     /locus_tag="LP245_001006"
     CDS             31278..32669
                     /locus_tag="LP245_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1518939.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32742..33389)
                     /locus_tag="LP245_001007"
     CDS             complement(32742..33389)
                     /locus_tag="LP245_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBL1518940.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33397..34083)
                     /locus_tag="LP245_001008"
     CDS             complement(33397..34083)
                     /locus_tag="LP245_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1518941.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34089..35162)
                     /locus_tag="LP245_001009"
     CDS             complement(34089..35162)
                     /locus_tag="LP245_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1518942.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35384..36058
                     /locus_tag="LP245_001010"
     CDS             35384..36058
                     /locus_tag="LP245_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1518943.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36063..37403
                     /locus_tag="LP245_001011"
     CDS             36063..37403
                     /locus_tag="LP245_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1518944.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37552..38538)
                     /locus_tag="LP245_001012"
     CDS             complement(37552..38538)
                     /locus_tag="LP245_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBL1518945.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            39262..40293
                     /locus_tag="LP245_001013"
     CDS             39262..40293
                     /locus_tag="LP245_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1518946.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            40402..>40827
                     /locus_tag="LP245_001014"
     CDS             40402..>40827
                     /locus_tag="LP245_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBL1518947.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
BASE COUNT        12679 a         7413 c         7663 g        13072 t
ORIGIN      
        1 taataaaaaa taggagaaaa agtagaaaag aaggtgtttg ttatttggga agtagttaaa
       61 tcgagagtac aagaaatgaa tgaacatttc tcagtgtcat tcgcagaaaa tccaagtaag
      121 tattttcgac gtcttgtttt tctgctcatc ttatcattgc tgttaacagt tgcaatgttt
      181 ttattgccgg aaaaaatccg agaagagcaa gtaaatagtc tcgtttattc gtccatacca
      241 accagcaaat tgaaaccttt tgattacagc aaagctgatc agaaaatcaa acaaagccgg
      301 gcgatatcgg tgatgttcag caaaccgaac gggaaaacct atcaggacat gcttgatgtt
      361 tttaatgatc ctgagcttat ggaagaattg aatcgaccga tcttttatta tccgatcgtt
      421 tatgatgtac atgaactgga acaaaaatat aacatacgaa cggatgaagt gacatttatt
      481 ttctttgatg gaggaaaaga agcaaatcgg ataactgcgg gtaagggagg aataactgat
      541 tttgataagg agttgatccc tgaactgaat cgacttccgt tagccaatat caaacaatta
      601 gaagaagaat tggatagaac gggagtaact tcccaaaatt ccgagattgc taattgagac
      661 attggcgcga tgaaacggtg ggtctatata gcgctatttt taattatcag aacaagtgat
      721 gtttgatctt caaaataaca aataaaaaat taaaaaatat agttgacgaa attcaaaaat
      781 tcgattagac ttaaatcaat tcttaaggaa agggtgacct gtaatgaact tatcaaaacg
      841 tatttcagca gaaaacaaaa aaaattggcg cagctggcgt agataagttg tattaatggt
      901 gagactttcc catagataca actttttaga gtgcatttct aaagcttgta tctatgctag
      961 acatgaacat tgactgccgc atagattaga atctatgcgg ttttttgtgt aaagacaatg
     1021 accgctttgg ccattgtctt tttttgtaga ctggatactt gcctgattat aataaataaa
     1081 aagattgact ttgcaggagg aaaaaaatga aaaacaaacg attaataaca gttgtagtaa
     1141 ttattttagt ttatttagca ggtgcattta tttatggaaa agcctcaggc gaaaaagaaa
     1201 gtacttcgac gaaccagaca aaaaaaacaa cagttgttgg ggtattgcaa tacgtgagcc
     1261 atccggcatt agatgagatt tatcgaggaa tcaaagatgg tctgaaagaa gaaggattaa
     1321 aagaaggaga aaatcttgag atcaaatttc aaaatggaca agccgatcag agcaagctag
     1381 ccacaatgag tcaacagcta gtacaatctg atccagatgc cttgattgga atcgcaacac
     1441 ctgccgctca atcattagca aacacgactt catcgatccc agttgtgtta ggtgctgtaa
     1501 cggatcctgt gggggctgga ttagtcgctt ctttagagaa acctggtggt aatgtaacag
     1561 gtgtttctga tcagccgcct gttacttcac aaatcaagct tgcttctgat ttgttgccaa
     1621 atgcaaaaaa agtcggaatc ttgtatgctt cttcagagga taattcaaaa taccaagtag
     1681 cacaagcaga agaagctgca aaaaaagaag ggttagaatc agtaaaatat gcggtgcctt
     1741 ccactaatga gattgcacaa acggttcaag tgatgagccg acaagtcgat tttatctatg
     1801 ttccattaga taataccatt gccaatgcga tgcaaacagt ggtaaaagaa gcaaacaaag
     1861 caaatatccc cgtcattcca tctgtggata caatggtgga acaaggtgga ctagcaacaa
     1921 tcgggatcaa tcaatatcaa ttagggcttc aaagcggtaa gatggcggca gaacttgcga
     1981 gtggaaaaga aaaaccggaa acgacgcctg tttatacatt tgatcaaggg gatacagtga
     2041 tcaatcaatc tcaagctgat cgcttaggaa tcattgttcc ccaatcgatg aaggaaaaag
     2101 ccaaaatcat tacagatgac tcgcagcaag aaacatctaa ggaggatgac aaatgatcgt
     2161 atcagctatt tcacaaggca tgctttgggc aatattagga ttagggattt tcatgactta
     2221 tcggatctta gactttcctg atatgacgac agaagggtcc ttcccattag gtgctgctgt
     2281 ctgtgtgaca gctattactc atggggtagc gccgattgta gctacattat taggcgtagg
     2341 tgctggcatg atagcaggac tcgttacggg gttactttat acaaaaggaa agataccggt
     2401 tattttagca gggattttag tgatgtcagg attgaactca gttattttgt ttgtgatgcg
     2461 aacaccaaat ctttctttat tgaatcatcc gattctacaa gacagcttcc atcgctttgg
     2521 gttacctgat tactttgaca cagtccttct tggcttcatc tctttgggca tcttgattgc
     2581 tgtactgcta ttcttcttca atacagattt gggtcaaggc tatattgcga caggagacaa
     2641 cgaaacgatg gctcggtcgt tagggataaa aaccgatcgt atgaaaattt taggtttaac
     2701 tttgtcgaac ggtgtcattg cattatccgg tgcgctgatt gcccagaacg acggatatgc
     2761 agatgtaaat aaagggattg gcgtaatcgt catcggtctt gcttccatca tcatcggtga
     2821 agtgatcttc caagaattga cgctagcaga aagattgatt gctattgttg tcggcagtat
     2881 catttatcag ctattgattt tagtagtaat caaactaggg tttgacacga cttatctgaa
     2941 gttgttctcc gctatcatct tagctatttg tctgatgatc ccgcaattga agaaagcact
     3001 gaacttaaaa acgggttttg agaaggaggc atagtaatga ctgatatatt gacaatcaaa
     3061 aatggcagaa aagtcgtaaa caatggaatg aatgaagaga aagtactatt ggatgaaatt
     3121 aaccttacaa tcagagaagg ggacttcatc actgtccttg gcgggaatgg tgctggaaaa
     3181 agcacactgt tcaatacgat cgctggtacg cttcaactca gtcaaggatc gatctctttt
     3241 aaagatcagc tgatcacaaa agattcagaa gaaaaaagag cacgattcct ttctcgagtt
     3301 ttccaagacc ccaagatggg aacggctcct cggatgacag tagcagaaaa tttgctactt
     3361 gcacaaaaaa gaggtcaaaa acggaaattc cgtttacgta acttgaaaaa tcaaaaagaa
     3421 gattttttca gactatgtca agaagtcggt aatggcctag agcaacactt ggatactcca
     3481 gcgggtgaat tatctggtgg tcaacgccaa gcattaagct tgctgatggc gacgatcaca
     3541 gctcctgagt tactattatt agatgaacat actgcagctt tagatcctaa aacagctaaa
     3601 gcattaatgc gattaacaaa tcagcggatc aatgaacaaa aattgacttg tctcatgatc
     3661 acgcatcgaa tggaagacgc cttgaaatac ggaaatcgtc tgatcgtact ccaaaaaggg
     3721 aaaatcgttc aagatatttc tgaaaaagaa aagcaacatt tgacaatggg cgaccttttg
     3781 cagttctttg aagaagtagt ggattgattt cgacagaaaa attcctttca gtagaaggac
     3841 ttgaaaactc attgacatct tcctttgatt catcctatac ttaaaacaat aaacaattaa
     3901 acatatttgg gtgttttgta ggatcacgta gtcaatgatt ttaacaatta aatagaatat
     3961 tctttgctct gacaagtaaa cgatgagaaa agaatttgct actttgccac ctagacgttt
     4021 cgtacttttt cgtatcaaac gctaagtggc tttttttatt gaagtaagaa caaaggagga
     4081 ataagatgat ttctggacaa accaaattag ctgggctctt tgctgatccg gcttctcaca
     4141 gtttatcccc attgatgcac aatactgctt ttgaagcaaa caacatcgat gcggtgtatt
     4201 tagctttcca agtaaatcca atgaatttga agcaagcagt cgaaagtatt cgaacttttg
     4261 atatgttagg tgtaaatctt tcgatgccga ataaaacagc ggttattcct tatctggatg
     4321 aggtaagcca ggaagcgcaa ttgatcggag cagtgaatac gatcgtgcac gaaaagggtc
     4381 gtttgattgg ctataatact gatggtgcgg gcttcatgca atccgtgcaa gaagctggga
     4441 tttcgatcaa aaagaaaaaa atgactctac tgggagctgg aggtgcagca aaggcagtca
     4501 ctgttcaagc agcgttagac ggcgctgagg aaatcgtagt ttataaacga aacaaccaaa
     4561 cattcgctca agtaaaagaa acattcgaac aactcagcta tcgaacttct tgtaagataa
     4621 aagttcgtga ctttgccgat acgcatcaat taagaaaaga cttgaaagaa agctgtcttc
     4681 tagtcaatgc aacagatatc gggatgggaa agaaaatcaa tcagtcaccg ctcttagata
     4741 taagcatgat gcatgagaat ctagcggttt ttgatttgat ttatgcacct agagaaacac
     4801 gtttattaaa agaagcaaaa aaagtaggag caaaaggata caatggactt ggcatgttga
     4861 tctaccaagg agcaatcgcg tttgaattat ggacaaagga aaagatgccg atccatgtga
     4921 ttgaaaagct gtttgattaa aaaaggataa tagataaaga tcttttattc tcgcataaac
     4981 ggtctcaaga aaagtaatcc tttatgtatc gaagcattta tttcgttatt ttttattaaa
     5041 ttatcaaaaa atgataggct tttgtcgatt ggttatcgta tcctttattt atcagtaaga
     5101 aacgaggagg aaccacaatg agtcggatgg atcgctataa ggacatccat aagaaggcga
     5161 aacctctgaa gcgggatacg gggagtattt ttgctagaag agaacgaaaa cgaacgcgta
     5221 tggaaaatga ggaagatgct acccgtattt atgaaagaga gcagcattca tttgaacatt
     5281 tgaaccaata cgagcaacag atatacagag atgcaccaag agcagaagaa caacaaaaaa
     5341 ataaaaaatt tttcaatcgg caaaagaaga acaaaccgtt aaaacctcga agaaagcgat
     5401 cgtggaaaaa aatcattcta tcgattttgc ttgttttgat cctttattca ggtatctcat
     5461 tttttattgg taaatatgta gctgaacatg acacaagctt agaggcagcg acttcagaaa
     5521 cctttcatgg gcaaaaagcg acgaatggtg cgcataatat tttgatcctt ggaagtgata
     5581 cacgcggaga agatgccggg cgagccgata cgatcatggt cttacagttg gatggtcctt
     5641 cccataagcc gaaactgatt tcttttatgc gtgacagctt cgttacgatc ccaggggtag
     5701 gacaaaataa gatcaattca gcttatgcat acggaggagc cgatctagtg cgtcaaactt
     5761 tagtagaaaa ttttggaatc gattgtcaat actatgcgaa agtcgatttc aaatcgtttg
     5821 aaaaagtgat cgatgcctta ttcatgaacg gagtgaagat cgatgcagaa aaagatctga
     5881 atctggatgg tgtagatatt aaaaaagggg gccagaagat ggatggacat gttcttttgc
     5941 agtacgcacg tttccgaatg gatgaacaag gagactttgg ccgtgtcaga cgccaacagc
     6001 aagtaatgaa cgctattttc agccaattga agaatccatt gaatctgatc cgtgcacctt
     6061 atgcagctgg taaagcttta ggatatacat ccacagatgt cactgcttgg ttcttgacga
     6121 aaaacctctt ttcgattgca cgaggagctg gtggcattga tcgaataagt gtgccagtag
     6181 acggttcgtg gaattatggg caaagtgatt atgctggcag tattcttgaa attgataatc
     6241 aaatgaatca atctgctatt acagattttt tgaataaatg atcataaaaa agatcaagaa
     6301 gaagctgcgc aaggcttttg tcatgaatca atcaaacgat tcactcgtaa aaaacgcttt
     6361 cttatggtag atttaaccaa gagaggagct gtttacattg gatatctatc tgaacttcaa
     6421 aaatgagtcg cgtgaagcca tcgcttttta tgaaaaagtt tttcagactg aagcatcagg
     6481 tatcaccaca tacggtgaaa tgcctggaat agaacaaatg aacttgccag aagaagcaaa
     6541 aaatctaatc acgaatgcac ggctgaacat ttatgataca ttagttatgt ttgcagatac
     6601 gccagaagga attggtcctg aattagttgt gggaaataat gtttctttag tcatccagac
     6661 aagaaatgaa gaagaaacga agcgcctatt tgaaagctta gctgagggtg gtaagattga
     6721 gatgccactg gatgctgttc cgtgggctca gttgtatggg atggtaactg atcgatttgg
     6781 catcaactgg cagattaacc aagagtgaca gctaaagatg aatattttct ggaaacatca
     6841 agcagcaaac ggatcatcgt ttgtttgctt gatgtttttg tgtctatttc gactatacgg
     6901 tatctttttt ttattgccag atgcgaaaat atgttccata atagagaagt ccgcaaaaaa
     6961 ttaagtaacg gaggtcagaa gatgaagacg gtgatactag ctgaaaaacc ttcacaagca
     7021 aaagcctatg ccgaaacctt ccaacagcaa aagcggcatg aagggtatta tgaaatcagc
     7081 gatccattgt ttgctggtga agtaaccatc acttatggtt ttggacattt ggtagatatg
     7141 gttgctccag gagcttatga agagcgttgg gcaaaatggt ctttagaaaa tttgcctatt
     7201 ttcccagaaa ccttccgtta cgaagttcca atggacaaac gtgcacaatt ttcgatcgta
     7261 aaacgagaat tgcagtcagc cgataccatc attattgcaa cagatggtga tcgagaaggt
     7321 gaagccatcg cgtggtcgat tattcgacaa gcaaacgcat tttctaagga aaagaactat
     7381 ttacgtttat ggatcaattc tcttgaaaaa gaagcaatct atgaaggttt taagaatctc
     7441 caacctggaa agaactattt tccaaaatat aaagaagcgc aagcaaggca gaacgctgat
     7501 tggctgattg gaatgaatgg aagtccatta tatagcttgc tacttcaacg aaaagggatt
     7561 gatggcagtt tttctcttgg tcgtgtacaa acaccgacac tctatatgat ttatcagctg
     7621 caagaagaaa tcaaacactt caaaaaagaa acgtactttg aaggagaagg tttaattacg
     7681 acaaacaaag ggcagttttc tggaaaaatc gtaccaaaaa aagcatttaa aacccaagaa
     7741 gagttaacga aggaaataga aaaacttgga gcgcatttag gtaagcaaaa cggacggatt
     7801 cttgaagtta cgaaaaagga aaagaggttg catagtccac gtttattttc gctatctagt
     7861 ttgcagacaa agatgaatca gctaatgaaa gcaagtgcca aagctacact tgatgctgct
     7921 caaggattgt acgaaagcaa gtttctaagc tatccaagaa cggattcctt ttacattaca
     7981 gaaaatgagc atcagtatct ggttaaacat ctgcaaaatt ataaaaaatt tttaggaata
     8041 gaagaagtac agacaactga gatcaaagca aagaaacgat atgtcgatgc gaaaaaagtt
     8101 caagaacatc atgcaattat tccgacaaag acgattccga ctcctgcacg ctttgcgaag
     8161 ctttccaaat tacagcaagc aatctatttg caagttttgc gcactactgt ggctatgttt
     8221 gctgcagatt atatctacga agagacgacc gtaatgacgg gcgtacagca attaaagcta
     8281 aaaagcatcg gaaagatccc attacagcaa ggttggcagg aaatcttacg catcaagtca
     8341 aaaaagaaag aagctcagac tcttcctcct atcgtagaaa atgaagaagc agaagtagaa
     8401 ctgaaaagta tggagaaaga aacacaacct ccaaaaccct ataccgaagg aacgttgatc
     8461 acagcaatga aaactgcggg aaaaacgctg gataatgatg aagcgcaaga aattctcaaa
     8521 gaagtagaag gaatagggac agaagctaca cgagccaata tcattgaaaa tcttaagcag
     8581 aagcattaca tcgaagtcaa taaaaacgaa ataactgtta cgccaaaagg aatcactctt
     8641 tgtaaggcag tagccaatga accattactg acgagcgcag aaatgactgc gcgctgggaa
     8701 gggtacttga gaaaaattgg taaacaagag gggacaccat ctgttttttt agagaatatc
     8761 aaaaaattca tcctacattt attggcagaa gttcctaatc aaatcgacaa ggtagacttt
     8821 tcagatgaga ttagcgggac acgtcagata aaagcgatgg agaagaaaaa cgatcaatta
     8881 ggaagatgtc caaaatgtaa aaagggaata gtcatgcttt atcctaaaat cgctacatgc
     8941 ttgaatccgg aatgcgactt caaattgtgg ccaacagtag ctaaaaagaa gctgactaaa
     9001 acgaatctca gagatttgct ttcaaaagga aagacaagta aagttgtcaa aggttttact
     9061 ggtaaaaaag ggaaattcga tgcagtttta gtattaaaag aagatatgac aatcggtttt
     9121 tcttttccat ggatcgaaaa cagtggaaca aaagcagttg atggaaacaa agaaacatca
     9181 agaaaaaata atgaaaacga agtagagtaa atgaaaacaa tgaaatagcg gaatatttat
     9241 tccgaaaagt gagaatataa ataccaataa aactaaaaaa tatcagtgaa tcaagcaaaa
     9301 acgttggggt aggctgattt tatatagata gcaaggagtt tttttatttg aaaaaagtgc
     9361 attcattttt aaattatctt atgggagcaa tcacgattgt ggctgtgtac caagcatttc
     9421 taaagtatcc tgattacggg acgaagttgt tgtcattgac gcacaatcaa acagcatatt
     9481 caccaacgtt gattttatcg actttgactg caggagctaa aagcgctact tatttttttc
     9541 ataaaacgac aagcatgcta aagcgaaaga aacagcgaaa acaattgttg gtggtggtag
     9601 cggctatgat cattatttat tttctaccag ttattacaca agtatttcat caatattttg
     9661 gttaagaata cgagagtttg tgacaaaagt catgtcacaa acttttttct ttgtcatttt
     9721 ttcgtaagaa aaagcaaaat aaaagtatat acattgatta aaagtatata cttggatata
     9781 atgtacttac tatagaatga gaatggtata gagggtggcg aaatatgaaa aaaatgaaaa
     9841 agtataaaat tagaaaatct ggcaatagcg atgtaacaac tatcccacca gaagtaaaag
     9901 aattcatggg tgtgcagaca ggtgacgcaa tcagttatgt ttttcaatct gatggttctg
     9961 tacgaatgat caaagcacaa gaagaacctg atattgattc attagttgat tcgatcatga
    10021 atcaatatga agacgcgtta aaagatttgg ttgatttatg aggtatcttt cgactaaaga
    10081 aattatcaaa atcaacgcga aagttatttt acgtcactcg ccaggcgaaa tgatcggtgt
    10141 aaaagatgca aatgcattag atatggccgt caaacagcct tcacaagcag tattcaatca
    10201 agaactctat cctgaaatct atgaaaaagc ggcgatttta gcaattaatt tagctaaaaa
    10261 acatcctttt cataatggca ataaacgaac tgctcttgtt gccatgttgt tgtttcttca
    10321 attgaataat tgtccagttg ctttttctcg tcaagaagct gttgatttta tcataatgat
    10381 taccactagt tcattggatt tcgattcact aaagtccaag ataaccagtt atttacgaca
    10441 aaccgcaata aaatgaacga attaaaaact ttatttctca attagatcag catgtcatta
    10501 aggaatatgc tgattttttt atgtttaatc atacaaaata gttttttcat aaaaatatgg
    10561 aaaatatgga ttaattttga aataattgat ttaaaaggaa tacaaaagag tgaatagtag
    10621 gaaatagtgg tttagaacta gtgggctgat tttttatata ttttagttta cataatatat
    10681 attatacaaa gtagatttaa aaaatgataa acctctctcg aacggttttt tatcaaaaat
    10741 cgtcattttt ccatcaaaat ctgcttatgc aaaattataa aaaaattttg cagtttttct
    10801 tacttttttt gtcgtttaat tgaatgataa aaaccagttt ctttattcag ttaatcaaat
    10861 atgaacgaat tagatatgaa tcattgtatt tgccgttgcg gaaggatttt ttaattaacc
    10921 acagataaac attgataacg attcgcttat tgtaatcaac agattaaatt tcatatgttc
    10981 atatgtacgg atacattttc ggaccgatta attttaacca ttctgtttat ttgcttacct
    11041 attagatatc aataaaaaac tgcttaacag ctatttcagc tgttaagcag ttttaggatt
    11101 tttagttcat attcattgtt tcttataata cagtgttcaa tacttctctt aaagcacttg
    11161 ttgatttgct gaacattgct ttttcttctt cgttgattga taattcaaca acttcacgaa
    11221 caccattttc gtcaacgatt gatggcacac ctgtaaagat atctttttcg tcgtattcac
    11281 cagttaaata agcagataca ggcaatacag cttgttcgtt attcaagata gcttttacga
    11341 tacgtgcagt actcatacca ataccatagt aagttgcttt tttacgatca atgatctcat
    11401 aagcagcatt acggacttta tcagcaatca catctaattc atcttgggca atacgatggt
    11461 ctttttctac aatttcaaac actggtttac caccgacagt tgtatgtgac catgcagcaa
    11521 cttctgaatc accatgttca cctaagatat agccgtggac gctgcgtggg tcaactttta
    11581 atttcaatgc gatttcttta cggaaacgag ttgtatccaa tgttgttcca gtaccgataa
    11641 cacgtgatgt tggcagacca gattcgttcc aagcgatata tgtcaaaata tctactgggt
    11701 ttgaagcaac aacgataata ccgtcgaatc ctgatcccat gatttctttt acgatttggc
    11761 gcatgattga cgcatttgtt ttaactaaat ctaaacgaga ttgaccaggt ttttggttga
    11821 taccagctgt gataacaacg atatcagcat ctttacattc ttcatagcca cctgaccata
    11881 cagccacatt ttcatcgccc caagccatac catctaaaag gtccaatgct tccccttctg
    11941 ctttttcttg attcacatcg atcaatacta attcattaga gattccttgg ttgatcattg
    12001 cataagcgat acttgttcca acaaaacctg taccgacgat tactacttta cgacttgttt
    12061 ttttcatgaa taaacagctc cttttcataa ctatttgtta ctttcatgaa aagtatagtc
    12121 ttgtttattc attttatcaa catgttaatt ataatagttg ttattataat ttttgatgga
    12181 aacgaattcc tgaatacgca taacagataa atgacaaatg tttacaccta tatcccctga
    12241 taatacaacc aaaagtttag aactgaaaat aaatccaaaa aaattcgctg caacgatata
    12301 ataagacagc aatcgcacct aaaacaattt tccttcatat gctttagtga aagattttct
    12361 tcttaatgtt tatttctcca ttcattggga gtacatgttg aatacttctt gaataatttg
    12421 aataaagaag tcgtttgttt atatccgata cgattagcga tttcttccaa cgaaaaactc
    12481 gtttcttgaa tcagttccaa cgcaaagtcg aattttttct ttagaaccag ttcttgaaag
    12541 gaagcatcaa aatacatttt caatttatta ctaagataga ccggattgta gccaaaatga
    12601 gctgctgttt cttttaacgt acaagaagta aaatgcttat cgatataatc taatactcta
    12661 agcatctcat tttctgcgca tccatctgct gatgaaaagc tttgttgttc taataaatga
    12721 gtcaattcga tcagtaatag tgatgtatag agatttaacg aacggatctt atgactgtat
    12781 gtatcaaaat aaatcaacag catattttca atcaaatgcg tcaaacgact tgtttttccg
    12841 ccgcgaaaat gaatgaattg tgtatgttcc cctttttctt ttgatgcatt tatcaaaaaa
    12901 gaagaaagta gattatttgt gcttgccaaa tgattcaata tctctgtaga taaggtttct
    12961 tcttttaata agatgttgat taaaatatcc tcttgccctg tgtattcgat tctttgagta
    13021 gcttctttat caatgatcac cacgtcactt tcttccatct ctatcctttc tccattaata
    13081 atttgtaaac atgtaccgct atacatataa ttgatttcaa caaaatcatg tgtatgctcg
    13141 ggaacttccg catatcgacg gtgtttactg atatgaatat ttccctgttg aaatagatcc
    13201 cctcggtgga tttttggcgg tgtctgaaga tggtaagcta agtttaaatc attgatattc
    13261 attccttgtt cacgctgcag agtttcgatt gattcttcgt tacgcaaaaa aaatgtctaa
    13321 ttcagctagt tccaattgac tccctccttt ttgtaagcgg tttctttcgc ttattagttc
    13381 acgctgtact gctattatat gcaaagctat ttttggtttc ataaagactt tctatggttg
    13441 ggacatgaac ttcctgtgat tccgctattg agagaataac cacttcatac tatatttttg
    13501 ataagcgctt acaaaaatga aaggaacatg cttatgaata aaaagatgat gaaattttct
    13561 ctgctgtcag tctctcttat tttgacttct gctggtgcag tcacgtctgc aattcccagt
    13621 atgtcagcta cttatgccac gcgttcttta tctgctgttg aattattaac gactgctccc
    13681 tcttttatgg tcactatttt tgttttgatt agtagtttta ttgctaggaa aatcggacaa
    13741 aaacaaactg tgatcatcgg attagtgatt gcatcgattt gtggtatcct ccccctcttc
    13801 tcacaaagtt acagtattgt cttagcttca agagctggac taggtattgg ctttggattg
    13861 atcaattctt tggcagtcag catgattgct gccttttatc acggagatga acgagcctct
    13921 atgattggtt ttcaaagtgc atttcaagga tttggtgcag ctttaatgac atttgttgca
    13981 ggacagctag tacagttcgg ttggcaatat acctttttag tctacgccat cagcttacct
    14041 attcttgtct tgtttgtttt gtttgttcct acacctgaaa caactgaact tcaatcgcat
    14101 ggcacagccc caacaagaca agtaatcaaa acgaatccta aaatgattag ttatggtatt
    14161 tttctcttgc tggtcatcgt ggtatataat gctgtatcga ttaaattagc cacagtcctg
    14221 acgacttatt ctctaggaaa cgaaactaat gcagcgaata tcttaacaat catgcaattg
    14281 gcaagtatgg ctgccggagt ttgttttggc tggcttcaga caaaagcaca tcgctatatg
    14341 cttacacttt ctttactact gatgggaatc ggctttgtat tgattgccac tgtgataaac
    14401 ctgtatgtga ttgggtttgg tgcgatccta acaggaattt ctttttcgtt attcattcct
    14461 tacttattca accaagtaag tatccaagcg cccaagtacg cggagagttt caatacttca
    14521 atcttattgg ttggcgctaa tttaggtact ttcattgcac catatggttt gctctttctc
    14581 tcttttgctt ctcttgggag taaaacactt gctgttttcg tcaatggcag tatcttgctg
    14641 ttgattagcg cgcttattag ccttctagta gtacacagga cgaatagaaa gacagtgata
    14701 agagtagatg aagaaataaa agaacaattg acaacaaaat aaatttgatg gaggtcgtgt
    14761 aaaatgacaa atgaaaaaca taaagataga tggctttggt atcctggaga ctttgagatc
    14821 cgccatggac tgctacaaaa tttccaacgg gaagaacgag gttttgactg gccagcgtac
    14881 tggtacatgg atgattgcca tcggaacgtc aagtttaaga gatattactt tcttgatcaa
    14941 ccttccatgt ttaaagtgac gatccaagga gttgggtatg tagaaattaa tggacaaaaa
    15001 catccatgtg gaaaatggct gacttgtcca gctggtaaag caaaaattcg tatctttgta
    15061 ggacatacat cagggctacc agcgatgttt atcgagggag acgaagtaaa atcagatatt
    15121 ggctggacag caagtaattt tattgaagaa tatccagctg gctggagtcc gctttatgtc
    15181 gatatcgcaa aagatccaaa tcaaatctat tatcaaaaag aatgcgtcca tccagtcact
    15241 gaaacggaga ttggcggagg aatcttattc gattttgggc gagcagtgaa tggctgtgta
    15301 gaactaatat ctctggatga ccatatcgaa tctatcactc tatgttatgg agagtccgat
    15361 gtagaagcta tggatatcga ttattgctac tataagcaaa taggaatgac aagaaaaatg
    15421 aaagctcgta aacgcgcttt tcgctatttg tttataccag aggtttctac tggaatggtt
    15481 caacttcaag tttttcatga atttttatct ctttcgaaac aagctgcttt ttcaagcgat
    15541 tcttctttac tgaatcagat ctggtcagta tcagaagaag ccttcaagtt atgtagtgat
    15601 ttgtttttta tcgacggtat caaacgagat cgctggattt ggtctggaga tgcgtatcaa
    15661 tcattcatga tcaatcaata tctttttttt gacgaggaaa tcaataaacg aacgatatta
    15721 gcattaagag gacaaaatga aatcaagcag catatgaata ctatcgttga ctattcgatc
    15781 ttgtggttga ttggtatcga aaaccactat atgatgacga aagactatga atttttacgc
    15841 atcgtctacc ctaagatgca atcattaatg agatacttga tggagcaaac gaatgaatta
    15901 gggtttattt atgggagagc aaaagattgg atatttattg attggtctga aatggataaa
    15961 gaaggaacgc ttgctgcaga acaagtctta ttactgaaag cctatcattc catgatcact
    16021 tgcggagata tcttagctga aacatatgga gagaacgaaa attatcatac tcatctctat
    16081 caagaaaaat atcaactatt gaaacaaaac ctatttgact acttttggga tgaagaactt
    16141 ggcgctttta tcgattgcta tgaatctggg agaagaaatg tgacgcgtca tgcgaatatt
    16201 ttcgctgttt tattcgattt tgctaacaaa gaccaacagc aatcgatctt aaagaatgtc
    16261 ttattgaatg acactatcac acagattact actccatatt tcaaattcta tgaacaagat
    16321 gctttatgca aactcggaca gacgaatatc gtctaccaaa cgattcttga ttattgggga
    16381 gggatgttat ctcatgatgc ggtaactttc tgggaagaat acgaccctac tcaaacagga
    16441 aatgaaaagt acagtatgta tggagatcct tatggaaaaa gcttatgcca tgcatgggga
    16501 gcaagcccaa tctatctttt aggacgctat tttatcggtt tgtatccaac aaagccaggt
    16561 tatgaagaat ttatgataca acctaatcta gattcatttg aaacactgaa ttgtacgcta
    16621 cctatcaaag atggaaagat ttcgcttgaa aaaacaaaag ataagatcgt gattacttct
    16681 gatagaacag gcggaacagt gaaaatgaat ggtaaaagtt atcctcttct agcaaaacag
    16741 ccacttgtct taacaagcta ttcaaaaata aatgcataaa acaaaaaact gcttgcgaca
    16801 tatcagaaga ctttaaatct tcttctgata ttgtccaagc aatttttatt ttgaagtttg
    16861 cttaattctg ttctttagaa acaatgtttg ttctttttcc ggcaaaaaga aagctagata
    16921 atacgacaag taaaaagaaa gcgatgattc caactgtcaa ggctatttga ccgtattctc
    16981 ctagtttccc aagtacaagt cctggtacta gataatcagt atcggcaaat gtagaagaag
    17041 cgattttaag atctcctaat actggaagga taaataatgg cagccaacta atcaataagc
    17101 tattgaaagc agaacctaat accgcccctc ttctaccgcc agtcgagttg ccgaagacac
    17161 cagaagcagc tccgcagaag aaatgtccta ctaccccagg aatgataact gtagtttgca
    17221 agcctatcat agcaaacatg gatagtgttc ctacaaagaa gctaacaaaa aagccaatta
    17281 atacagcatt aggtgcatat ggaaaaacga taggaacatc taatgctggt ttagaatcgg
    17341 gtacgagttt tttagcaatc ccttggaatg ctggaacgat ttctgccaac accattcgaa
    17401 ccccttgaag gacgataaca aacccagctg tgaatgttcc agcttggatc agtgcaaaga
    17461 ttacagcgtt gtctccattg cttagttctc tttcaacaaa tccaggacca gctaacaaag
    17521 caagtgcgac atatacgatc gacatcaaga gcatgatcga tacagtagaa tctcgcaaaa
    17581 agctgaaact tttaggaatc tttatgtcct ctgtagaacg gtctttgttt ccaaaaaact
    17641 ttccgatcca tccactagaa gcataaccga tatttccggt atgccctaac gcaacttgat
    17701 tgtttccagt gatgttcttc ataaacggtt gacaaagagc aggcgtaata gttaatagtg
    17761 ttccttcgaa gaccccgcct aataagatca tccacaaatt tgcagtaaac cccgcgctta
    17821 ctaaaatgac tgctgttaga caagaaacat aaagcattgc ttgacctgta agaaaaatga
    17881 atttatatct tgtgaatcta gcaagtaaaa tattcacgat catccctact agcatgatca
    17941 aagcagtagg tgtaccgtat tgttgcaaag caatcgccac tactgcttca ttgctaggaa
    18001 ctactccttg agtatgcaga gctgtttgga acatcgaagc aaaaggggtt agtgaattac
    18061 tgattaaacc agcaccgccg atcagtacta ggaatccgac aaatgttttg atagttcctt
    18121 ggatcacttc tgaaaatttc ttcttctgaa gaacgagacc aagcagtgca atcaaagaaa
    18181 cgaggatgga gggctgactg acgattgaca caaacaaatt caacaattta tccattgata
    18241 gttcctccct tgaatcattt ttattctttt gacaagatct tcgttacttt ttcttttact
    18301 tcttcgctgt caatgatcga ttgcaaaggt acgagctttt catcaggtat agaagttagc
    18361 gtatctttca aagaatgctc aatgaagaaa taatcagcca tatcgctaga tacacttcca
    18421 acatccgtat gacttacttc aaactcgtcc acatctgctc caagatctgc aagtgcttgt
    18481 ttgatgttca tctctaccat aaaacttgtt cctaatccac tttgacatac tgcaaaaatt
    18541 ttcatatcat tcgtctcctt ttcttatgat cgctaatatt tcttcttttg ttgatgcgtg
    18601 taataaatct tgaagatttt gtttattaga aagtagcttt gttaaatttg ccaaagcccg
    18661 aagatgtgcc tcattatcga tagcagctaa acagatgaac aaactaatgg gatgggctgg
    18721 attatcaagc agatccacag gttgttgaag tttcagcaaa gacatcccta cttcgtttac
    18781 gccatcttct ggacgagcat gaggtaatgc gatgtgatcg ccaatatgga taaacgcacc
    18841 atactgctcc acgcgctcga tcatagcttt gatataactt tcttctattt tattttctga
    18901 taatagcggc tgtgcggcaa atgtgattgc ttcttgccag ttttttggtt gatccgataa
    18961 ttggatcatt tcttctgtta ataattcaga tagcatagga cgttgatcct ccttcttttc
    19021 taaaagtttg ttcattttac gatttaatac ttgatagagc ttttcttcgt ctacgccttc
    19081 ttttaattcg atataaggca gtagcgccga caacaattct tgggcagaag gcattgaaaa
    19141 tcctggtatc agccaatctc tttgtacttg attgatcagc tgattttttt ccaagtcagt
    19201 catgattgga tgcagaacat agagagactt tttcttatca gtaagtgtga gaggtacagt
    19261 agaaaaaata atatcgtaag aagtttcgtc aacctcgtgt aagcggtcag ctgaattagt
    19321 ctctgtaaaa aagatcatcg ggaataattg ctgaagttca ctttttaaga tcaatgaaga
    19381 gctaatgcca cttggacaga cgatcacggc tcttattttt ctatttcttt cttctgcgtc
    19441 cgcttttctg atctctccgc caaatagtat agtgaaaaaa ccaatctctt cttcagggat
    19501 gctcttccct attcgtcttt ctaacggaag taatgctttt cttgtcattt cgtagatgga
    19561 agcatattga tgcttaattt gatcgatcat cacattaggt aaataaaaag aataggaaat
    19621 acgaaaatag gcagggacca agtgataaaa gacattcatc aataattcac gaaacgaagc
    19681 aaattctacg gccatcagga attccatgcg atggatgact tctgaagaac attccagcaa
    19741 aaaatcaagt gcaggctcct ggacatctcc ttcaacgatc gatgctaagc aaagagagaa
    19801 aaatataatc tccgaatttt gatgttcgga atagccaagg ccagtcaata cttgtcgact
    19861 aatgtcagtg actgcaagag aagccaacag ttcagcatct tttaccagtt ccatggatgt
    19921 ttttccaatt cgaatggttg tcaaactcaa ataataagct aattcatcca ttcgatttgg
    19981 tgcgaatcga agatctgata gtgaaatcgt tttatctagc aaatctctaa ctttggcgta
    20041 ataatcaatg gaaagggttg cggttaaata cgtgagccca aatcttccag caagtgactg
    20101 catcaaacga gcagtgcgat tttttgcttc tcttcttaat attgcttctg accctagcag
    20161 cctaaaacca gttttcctag tatacgacag ctgacaatct tccacttcta attcatttct
    20221 tatctttttg atatctgaca ggactgtccc tttagaaacc tgaagaaaat cttgaaaatg
    20281 aaaaacagaa acagacgttg cagtcgaata aaccatcaaa taaagaagat ctcttcgctc
    20341 ttgttcggta tacacagctt caaatcgagt aatatccaaa aatttttctg cccagtcgat
    20401 tgctcggaat ttctttatac ggatacgggt atcatccaca tattcggcaa aaggagttaa
    20461 ttgtttgatc gcctcgcttg tatttacttc gatgatctct gctgcttttt ctagactgat
    20521 ttctcttggt gttttcagga gataactaat tttgtagttc acagcgctgt tcacctccta
    20581 cttatattct agtatggtag cgcttttaaa tcgaggggtg tttggtacaa cttacagttg
    20641 gatttttttt acgactgtac cgaacgattt ctatcgaatg gatacagaaa aaaagcaggt
    20701 gaccaaatgt ctcctgcttt tatgaattga tttcgtccga tcaatgatga tcatgtttat
    20761 tttttgaggt cagttcttca aatttttctt tgacatcttc aaccgctttt tcgatatctt
    20821 tttcaaagtg attgggctca ttaggctttg tttcctcttc tacagaattt gaaccagata
    20881 aagctgtttc tttattttct gtttcaccag agtttgtgcc agctaatgat tcttctttgt
    20941 cttctgtttc accagaatta gttcctgcta aagccacttc ttcttctgtt ttaggggcca
    21001 ttgaacctct taatcgtttg tgtttttcac cgtcataatt tgtcatgttg gttcctccta
    21061 gtagttctat actttttcat cgtacaataa gacagtttat gcgtcaaaaa acaaacccga
    21121 ttcttacaaa tatgtcatat ttttccttct gattcttgaa tgcttttgat tccttcttcc
    21181 aaaattttca tttgtaagat tgtttcttca tctttgatga ctttttctgc gccattaact
    21241 aatgtctcgt aaatcccttc gtagacacgg ctgtaatcac caacctcgga aattactttt
    21301 tcttcatgat aactcccttg ttcatctata taggtcaata caccataatg ttcgggcaaa
    21361 tcgataccaa agtcttcatg atcaggcatg taaaacattt tcagatgttc ttcttgtcga
    21421 tcttttgttt gtttcacgaa catccctttt tttccgtaaa cgacgaaact tggacgttct
    21481 ttgatgcgga aataactgga ttttatcgaa attttcatat ttccatagaa aaaatccaga
    21541 tcgaagtaat cattcattcg tcctttccct aaaagttgac gtacatcata gctgatatca
    21601 tctggttcgc cgaaataaga aagaacttga tctactgtat gacaagcatg tccatataaa
    21661 tagctgttcg cagtagaaaa ttcatgcgta ttttctggta cttccggtct gaaataatca
    21721 taatgcattt ctacttctaa aatatcccct aattttccgc tttcgattac tttttggact
    21781 gtcaagaagt cagaatcgaa ccgtctgttt tggtaacatt ggataaatag acctttttct
    21841 tttgctaatg caaataactc ttctgcttcc tttgacgttt ctgcaaaagg tttctctact
    21901 agtacattct taccatgttc gagtgccatt tttccatatt cataatgaaa ttgactaggt
    21961 gtagtgatga caactaattg gatctcagga tcatcccaaa gatcagacag ctgatcagta
    22021 tattcgatgt cttcgaatgt tttccacact ggttcagatg gggaaaaaat ttttttgata
    22081 ttgattttgt tcgtaagttt tcttgaaaaa ggcaaatgat agcgatttgt actctttcca
    22141 ttgccaagat aagcgattgt aagcatgagt ggtgcctcct tttattgatg ttttcagtat
    22201 atcctagaaa agcgcagaaa gtatttataa tagctattct ggtaaaaaag ttcagaaaaa
    22261 cacttgttat cattcggttt ggtgaaatta atgttcaaag taaggataaa aatcaaaaag
    22321 atagtagcgg aaccaagtgt ttatcagtaa gatagaattt ggaggtcaga tcatgcttat
    22381 tgaagaaaaa ctaacaaaac aagagttgtt taccacgaca gagaaacgga ttgtcgatta
    22441 catccgtagg aatatcgaag ctgcagtcta catgacgatt gaagaattag caaaagctac
    22501 gtatacttcc cattcagcta tcattcgttt atgcaaaaaa atgggattca gcggatttaa
    22561 agaattccgt ttcgagctgg ggcgggaagt tcatcaattg attgctcagt tcaatcaaac
    22621 gattgatcct aattttcctt tttcaagtga agatagcact cagcaaattg caaagaaaat
    22681 ggcggattta tcgatccagt caataaaaaa agcacaattg cagattgaac atgaagattt
    22741 agatcaaatc ggtaaagtat tgaacaaggc acagcgaatc tttctttttg caaaaggtga
    22801 ttctcaaatc acggcaagga aattccagaa taaaatggtc aagttgaata agtttttgat
    22861 catggctgaa gaatacagtg attcttcttg gaatgcagcc aatttgacta gcgaggattg
    22921 cgccattttt attagctaca gcggtcgcat ccatcattat gaacgaataa tgacctattt
    22981 gaagcatgta gaggccccta ccttgctgat taccggaaat cagcattcag aaatggccaa
    23041 acaggctgat atgtgtcttg ttatatcgca ggaggaatat gattttgcta aagtagcgac
    23101 tttctcctct caaattgcct tcgattacgt attaaatacg ttattctcag tgatatattc
    23161 tcaaaatttt gaagagaata tccgcaactt gaaaaacaaa caagaattga tgcaaaaagg
    23221 ccttcttaaa gaatatcgga aaacttaaga aaagatcctc atttagtaat aagaaagata
    23281 gtgtttgata ggctctcttt gatatcatca taaaaacagg ctgaagtttt ctttttcaaa
    23341 cctcagcctg tttgtttacg gaacgattcg aatagatata ttatagaaat gaggaatagc
    23401 taacttctgt ttcttatttt gaacgattga cgaaaaagat atataagaag gaggaaaatc
    23461 agtatacatg cagctaacaa tccatacagg aaaaatcgtt tgttctcgga tactttctgt
    23521 acttcttttt gaacttcttt tgcatgataa ggaacccggt gccctctgac aagtaagcga
    23581 tgactgttga ccatataagg tgtacaagtt aggagtgtca cgaaatcctg ccctttttcg
    23641 attctcagat cttttgtatc agtcggttct accgtcttga tctgatcgac ttgataagcg
    23701 agtgtccgtc cattgatttc gatatagaaa gaatcaccta aagtcagttt cggtaagtct
    23761 gtgaacaact ttgcttgagg cagtcctcga tggctggaaa taacggcatg tgtattttct
    23821 ccccccgtag gataagacgt tccttccaat aatgaggcac ctttttctag cagcacagta
    23881 ttcgtttcat caaaaattgg caaatggaca ttgatctcag ggatcgtcaa aataccgatc
    23941 gtatgtttct caaaataggt tctatccttt ttcgcaggtt cttttttctt agtaaaggga
    24001 tctgcacctg gatttccacc ttcttttgct aattgctggt ttttctttgt catgttttct
    24061 tggattttag ccatgacttc ttcattttct ttgaccgctt gttgctgata atgagagatg
    24121 atctgctgat ccagataatt attcagcgcg tcgctaacaa atggataagc tagtatccct
    24181 attcctgaga gaagcaagaa aagcatcagc agatctagaa gtttcctttt ctttggtttc
    24241 atttgtgttc tccttgtgat gactgtttga taataaaaga aaaaggagca tttgcgtaat
    24301 ccgctgctcc tttttccaat tcttgcaaaa agactaaatc tgactgtgct tgcgtctagc
    24361 aaagtacagt ccagcaatca gtagaaggac tactcctgca ccgatataca catagattcc
    24421 cttaccgcct gttgaaggaa gtgtaccttt gtgtttattt ggtatttttt caggagaaat
    24481 caactgtcct gctgttacat aagattgttc atcgatagta aatgctacac ggtttgttaa
    24541 tggaacatat ttttctggcg ctttcgtttc ttccagatag tacgtgccat attttagacc
    24601 tgtcacatcg attaaaccgt tacttgtggt tgtaaaaacc gttgctgatt ctttcgccga
    24661 tacccagctg acggcttttg tggatgggtc gatcgataaa tatttcgctg tgtcactatc
    24721 ttgatcacga acgacgaatt ctgctccagc aagtgtttgg tctgatgtaa cgtcaccatc
    24781 tactttaaca aatcgtttgc ccccagtaac gacatcgact gacggtggtg tttgatcatt
    24841 tgtatgcccg ttatcgacat ttgcttggtt agaaaatcct ttggttggat ctgctttttc
    24901 gttcaaatgc atatagtaaa cgaatttcaa tgtaccgcca ggagttaatg aaggaatata
    24961 attcggatca actgaaaccg tgaatccgtc tgtttgctca gtgacagaat aatttactgg
    25021 gtcgatttct ttatttccat catataaggc ataagcatac gttcctgaag aatcattatc
    25081 aaatgttaaa gcagcgtcat gagtatcgat aagtttgaat gttgtgtact tgttttgcgt
    25141 tccttcttta tcagcgatac ctaatgggat attgacagaa atctcatatt gaattttttc
    25201 accgattgcg acatcttttc cattcaattg aggtgttgtt ttatcaactt tagacgtatc
    25261 atttttgatg gtcttttcta ctggtgtttg gctatttgcc aggatctcaa aaggcgtgat
    25321 tgtttgcttt tcaatcattt ccgcattatc aggagctttt acttcttcta aattatattt
    25381 tccaacttct aaatgattaa cgatcaactg gcctttttca atagatgcct cggcaaagtc
    25441 attgttgccg atgtcataag aatgaccagt aatgaaatgt ttggctttgg tttgatcagt
    25501 tgtccaagtg tacaatccat ctgtgacact ttggatgtat tttttgacgc ttggtgttcc
    25561 ttcttcttta gaaataataa attctgctcc atttagtgct tcgttttcgg cagtaccgat
    25621 ttttgtaact ttcaacgttc catcattacc gactgtattt ttagggtaga gatggatagt
    25681 atctagttct tctgtcccgt atttataaga gccatctgct tgtttgatca tctcatatac
    25741 agggaaagct aaaaccatgt ttgcggcagc tgacactccg tcttttggtt cttctttgat
    25801 cgtgtagact gcatctttcc cattttgttt tttaggtaaa gataaagtga catttccatc
    25861 agcatctgtc gttcctgaag caactggtgt accaggagtc aaagactgga ctgcttgttt
    25921 tgctgcatcc acggacgctc ctttatctcg ttgcgcataa aattcttgag tgacgttata
    25981 aactgaaaat gaaatatcgg ataatccttg gtattgatcg aattcgctca tttctttccc
    26041 gctgttttgg attaaaggat cgggtaaatc agtcattttc tttttatgaa ggatgacttg
    26101 agctgctgtc tcctctgcaa acactttttt tgcgccgaag ctgtttgtga gtaatggtaa
    26161 aataaggaaa aggactccta acataacgtt tattttttta tgatttttca ttttttcact
    26221 cctgttcttt ttttgataaa caaccagatt gcaaagcttg cgaataccat accaacaacg
    26281 cctaaaagtg tatttttcgt ttcgtttgtt tttggaagaa atggacggct attttctttt
    26341 ttattgacta ctttcaatat actgtccgcc tctttatcct cagaaagaaa agttgaaatg
    26401 gtaaacggaa tttctgtttc acttaaaata taaccagaag gtgcttcgat ctcttttaat
    26461 cgataacttc ctgttttcaa cccggaaatt gaaaaagcgc catttttatc ggaaatcagg
    26521 tgaagcgcat ctgattcgtt ctttgtccac ttgtatccgt tggctgtttg ctggaggtaa
    26581 tttcctgctt tgtttttaat aaggaatact gcgccagcta atcgtttatc tggtttattt
    26641 gtctcgattt tgacaaattg cttactccct gtatatacag agactttctt tgtactgaca
    26701 ccaaaaccaa aatccagtgt tccgttgttg ttgatttcct tgttcgcctg tgctgtactg
    26761 cttagctgca tctgataaga aatggtcagt ttttttccag catatttttc caacgaaggg
    26821 atcgaaaata aaacatcaaa tccgtgaggt ttcttgtgta tgacaaagcc ttctgtcagc
    26881 ttttctccat tcgatgaaat cgttaaacta ttaggtaaaa acgttaatgc ttcatccgca
    26941 ctatctgaca attcgaactt ttgatagtca aggatattta caggaattgt cgtatgcaag
    27001 gaataagtga ttttttcacc aatcgtaaaa tcatttctag gctcttctaa taccttctca
    27061 aaaggtggat cagggtagtc gttttcttca tttttaggat acaaatggat agttgaaagt
    27121 ttttgattgt tttgtccatg tacaggaaga acaactacca tattctctgc cttttctttg
    27181 acgacttctg gtactttgga ttcaatgaaa agatacgctt tatctctttt ttcttgatct
    27241 ttagcggcca gagaaaaaga agcgatacca tcttcgttgt taagagttgt agttgttgct
    27301 tctgcggtaa acataccgga agacgcaccg ttttttgcga tctctgcttg tgcttcttct
    27361 accgttttgc ccttttcccg tagatggtaa aaagaatctg tgacatcata aacttggaat
    27421 gtgacaccat ttaatcctcg atacgtttgt aataaagctt tttcttgtcc gtcatttgga
    27481 tgatttttcg gcagttgccc gtttgggaaa agcaatttgt gtaaagtaat ctgaaccatt
    27541 tctgtttctg tttctgttgc tacctgagta aaagctggtt taaatagtaa caagaagaga
    27601 cacatactaa gccaaccaag ttttttcata tttagctgcc ccctctttct tttttcaaaa
    27661 aaagatacca aatagaaaac gcacaaccaa tcatccctac tagatagatt cctaaacggc
    27721 caattcctcc cgtttcaggt aatggtactt ttgcctgatt cgtgatgtct aaagaaatct
    27781 ggttgttttt ggctcctggt gacagaacag attcatgatc ttgtccatcc acttgaattg
    27841 acccatcttc gtgtataact atagtaactg gctcttttag accttggtat ccttctggtg
    27901 taaaagtttc ggtcagcgta taagttccag gttttaaatt ttcgaataga aaggtatctg
    27961 tttcttgtcc atcttttggc gattctaagt ccatttctgg tccctgcagt ctgaattttg
    28021 ctccttttaa tgtctgtccg ttgtcttctt ttttgtgtac cgttagatca aacgctttta
    28081 gtcgattttg atgagtgagc gtccatacat tatttgtcat ctcggtattt tttcccgtgt
    28141 aaatgatttt tccatattta tcgatttgga attcataatt tcccggcgaa gtatcatatc
    28201 cggcaggacc agctgtttca acgactcgat atttaccagg tgtgagtgaa tcaaaactgg
    28261 caagaccttt ttcattcgtt gtttggctgt caattggctg ataagtacca tttgcttctt
    28321 ttttctgtag ggaaaatgct gctcctttaa gatttatctc tttgtccgtc ccttgcatcg
    28381 catacttacg tactgctaca ggaacttcaa caaaaggatt ttcaatagtc aactggatcg
    28441 tatcatcgga agtagtgact gtttttccat caatggttac cgtaccatca gaagcgatct
    28501 tgatttccca agtagtcttt ttgcttaatc catgcccttc tggagctttt gtttctgtca
    28561 gcgtataggt catttctttt tgcaatttga cattttctgg aagagaatag gttccgtcgc
    28621 catgatctgt tagtaaagta tcaatagaat ctcctgttaa tttgaaaaca gcgccaataa
    28681 gatccttttc acctgtagag gaatttttcg ttattttcaa gtttaacggt gtgaattgtt
    28741 tagtattttt ccatgtcatt gcatctattt gttgagaatc gtatcctggt acaggtaatt
    28801 ctttgattgt ttggtaactg aatgcttgac cttgattatt gtattgaggt agtgataata
    28861 tctcttgata actttctccg ctatttgcag ataatttgtc aatgtctgca cgttcccacg
    28921 tatttgttgt atctttagct ggtttaatga ttcgaatata tccgtttttc caagctgcag
    28981 catttgtcgt atgttcccgt tgaatctcaa aagtaacttg atctggacga tcagctagat
    29041 tgttgtcaaa ttcttcccat aactttttga tgtgaagact gactccggga gctttagcag
    29101 atggtatacc gaattcagct aattcattgg tatcaatgtt tggctggaaa gttgtcctgc
    29161 cgttcatttg ataccagaaa tttggatgga agtcctcatt ttctgtttgg attctcactt
    29221 ggtaatggat ttggatttct tggtcttttc ctaaatagat ctgattgctc ttgatggtat
    29281 ttccttctat ggaaatagat ggagtgaccg ttgtaggact tgtccccaca ctcttgactg
    29341 aaagtgtacc aggctgataa atgaatggtt ctgcgattgg atcatttatt tgtccattgc
    29401 ttacagttgc tgagatctgt acagcttttt tggctaggta ttcagagata tctgttgcat
    29461 gatcagctga ttcatagtaa agatcgcctt tttcatctga tgaaaccatt tgtcgcatac
    29521 gagactctac ttctgctttt gagagaccag ctgccggatc gctttgaagt tggatgccaa
    29581 gaccatgtat ttcgattcct cgttctttga gtgccatcgc ttctccgatg gttgcgataa
    29641 acgtactgtc gattcttctg gatagattgt tttggtcagg tgcatcatag attcttgaga
    29701 ttagagaagt atttcccggc cgatcttgcg tattagaaaa ctgagttccg taataattgc
    29761 tgcttgattg tgcgtgtacc cgctgtactt tataggaaaa tgttggtaca ccatccgtca
    29821 gcaaaacgat cactttttta tgtccatttg gaacggatag catgcttcct gcatctctta
    29881 gtgctttttg tgtaaaagta ccaccatttg tccgtgaagg tgtaatggat tttacttgat
    29941 ttttcactga atcaaatgaa cccatctgta ctgcaccgtt actgtagcta tatccttcgc
    30001 ttgagtagcc gacatatccc atattgattt tgtctgtgat accgctatct gctaaagtat
    30061 cgacaaaacg atcgacacca atctttactt caccgatccg attattgtcg ttcatacttc
    30121 ctgaccagtc tacgaccaat acgagatcaa gaggcgtgat atctttttgt acatttccac
    30181 gagcattcaa ataaacatca aacaatccgg gtgtacttgt ttcctttgca tactttcgta
    30241 tcgcatagtc tgcttgatta ccggttcctc catattcgat atacgaatgg gtccgatcat
    30301 taggatctcc attccaagaa tttataccat cccattgatt tgttccgttt ttattgcctt
    30361 gatgatcaag aacatttgta tttcctgtag gttgccaact ggctttagga taagtgccct
    30421 gatcatctgt tgtatattct gtaggaatcg tttgattaga tggcacactc acagctggca
    30481 aggataatgt aggcaatgta aatgggctga cagaattttc gttttctttt gatgattctt
    30541 cttctatttc gtctggcttt ggtactgaca catctgtatc tttcttattt tctgtctcat
    30601 caataatgtc atattcttta ttatcgacga tcagcttgtt tgcctggctg tggtaaagtg
    30661 ctggatcgat tggaaaactc agatcgatag tttgtttagt gtttgatgag atttccaacg
    30721 taattttccc gctatttacc tgataagcat agccatctcc ttcttttctt tccacatcac
    30781 ttaagtaatt ttcgactaga ccaatttctt tttctatctt ttcagcactg gtgttattcg
    30841 catttagctt gatgttcagt gctttttttc cagactgatc cgaaatgact tcagctgaaa
    30901 ttgtttctaa aactgttgga tcatctgtag tgtctgctat tgcagataat ggcacaaagt
    30961 ttgataaact caatattatc agcatgaaaa taactttcag tttcttccct gtggtcgtca
    31021 tttttcccct cctttttctt tttttctgtt ttgacgtgaa tagtgaaaat tattaaaata
    31081 aacaggcgtt acataatttt atttatttta atatgataat tattatacga agggcgctaa
    31141 agggaatcac accaattttc ataccaattg gtttcattta tgaagttgat tccttcgatt
    31201 aatgagcgtt tcattgaaag aaaagggttg agggagaaaa acatatgatc aggttgttgg
    31261 aacgaaacta tagaaagatg gaaaaaatca ttcgaattct gtccatttct gacaagtgga
    31321 tgactaaaaa agaacttgcc aaacgaattg gtagttcaga atctacattt gtaaggtata
    31381 tcgaagagat caaaatccgc tggggaacgg atgtaacgat tcaatcttca caaaaattgg
    31441 ggtatcgtct tgaacatttg aatgtaccag cttatttaaa tgttctgatg gaaatgtcgc
    31501 aaagttctac aaacagtcgt ttattaaatg agattattgt caatccgggt aaaacgattg
    31561 agtattattg tgaaaaaatt tccatcagcc ggtcttcttt tacacgtaag ttgaaacaat
    31621 gcaatcaaat tttagaaagc tatttattaa aagtgatcgt tgaccaaggt tttcagttaa
    31681 ctagccttaa aagtgagctc cagttgcgta tctttgttac ctttttcttt ttaagttact
    31741 acggaagacg cacgttgcca tttccaatcg aaaaaaagaa gatcaaagaa attatggtca
    31801 agaataattg tcagatgaat ttgtttcagg aagaaagccc atatgagcaa tctttcttta
    31861 ttatgtattt tgttgtgcat ctcatgagag aatcccaagg aactccattt gaatggaaag
    31921 ctggagactc ttatgtacag ttgataaata tcgataaaaa agacttctta atcttgaaaa
    31981 atctcttagg aaaattgaag tacagcagct atataaaagt agtgaactat tttgtcaata
    32041 cgattttttc agaattttcg gagaaagaaa aaaatgaaat cagtgagcag atacgaaaaa
    32101 atatgtccta ctgttcgttt tcatccgctg attgcaaaga aaaaaacgaa gaatatgttg
    32161 ttcaattatt aacgcaaatt tattttttct cccgtatttt cccatacgat acgactcatt
    32221 tgacgatccg tgcaacttac tttgcacagc agatgcaaca ccgccagata cgtctatatg
    32281 ctggatttcg tgcagaactt caattttatt ccactctact gaatcagaat ctgatttatt
    32341 atttatctag ctatatcttt tggatgctta tcggtaatcc tgaaattcac cattatactt
    32401 ctgataaaaa aatactgatt atcagcgact taagtcttcg acatagtcaa tatattgaag
    32461 aatatatcag tgatattctt gctgtgcata aaattcactc tgagacaact gctattactg
    32521 aagatcagct gtcgaaatac aatcttctcg agtatgatct gatcgttacg aatcaaccca
    32581 ttttgaatgc ccatgttcct catatattga ttgatgatag tgtgtcattc gcaaatgaag
    32641 aagaactcat ccgcttattc gagttatgaa taatcaaaaa acagctatgt ataaaccacc
    32701 ctgataaaaa tttcaggaca aatacacata gctgtttctt tttattgtat tccttcagca
    32761 atccaacgag atttatagcg aaagtctttt aacaactctt cttttgtcca attatttgca
    32821 atgagatccg tcaaagtgtt cattacgagg gtcatggaaa agtataggaa actaactgct
    32881 tcttccgacg attgaatgga gaaatgattg attcttaata attccagcca tttttcgttc
    32941 attggagaat cagccgatag ttctctacgt ttggttgtct gctgatcatt tcgctgggtt
    33001 aacaagtata acctttgcca atagatactt tcgtgatcta agtcgcagca ccactctaaa
    33061 tatttttcga tccccaaaaa gaaatgttgt ttgttttcgc taatgaattt taagatatct
    33121 tgatggacta tgtgagaact gcttttgatc gtatacaaat aagcatcttc caaatcttga
    33181 aaatatttat aaaaagcacc gcgcgacatc cccatcttgt caacgatttc tgagactttg
    33241 acttggctga tgtgctgtga gcaaaatatc tccagtaata ggtcatcgat tctctgtttc
    33301 tttgcgttcg ataaattgaa aaaagtttct tttggcatcc acatctctcc tttatctctg
    33361 attatacgtg gatagccctt cattgtcatg aaggattcat tccttctttt tctcttcttc
    33421 tgtcaagtac ccatcttcca ttcgataaac gcgatcactc cattgaatca tacggacatc
    33481 atgagtaacc ataatagtcg ctttttgttt ctcatgagct tctttaacta gtaatttgac
    33541 gacttcatat gcatgatctg tatccaaact agctgttggt tcgtctgcta agatcaagct
    33601 tggctcatta tataaagcgc gagcaattgc cactctctgt ctttctccac cagaaaggtc
    33661 tttaggataa ctatttttaa gtgactggat atctaaagat tgcagcaagg aatcgatttt
    33721 tgttgaatct tctttttttg aagtaacttg gtcaactagt tcaaattgtt cctttaccgt
    33781 taaaaaagga atcaaattag agctttggag aataaatcct atttctttaa agcgtaaatc
    33841 tgctcgtttt ttttctggaa gctcagttag tgagtgaccg ttgatcacta tttctccgga
    33901 agtcggtgtt tgcaatcctc ctgaaatggt aaggaaagta cttttacctg aaccagaagg
    33961 accaatgatg ctgacgaatt ctccttcctt tacataaaaa tcaattgctt tcaaagctga
    34021 gacctttgta tgaccagaac caaatgtttt ggtaactttt ttcatcgtta atattttttt
    34081 catttttatt aacctcctat tgctgtaatt gggtctactt tggttatcgt acgtatcgaa
    34141 aacaatccgc ctagcattgc gacaatgatc aaaatcccac tatatagcaa ccattgtgac
    34201 caaaaaacag caaaaggcat cgcgcttggt aaaatcagac tagtcaaata agcaaacaaa
    34261 agagcaagca gaacgcctac caccccaaca ataaaggact gtgctactaa agatttagcg
    34321 atgaagaaat ttttgatccc ttgtgctttc attactccaa aaatagcagt cttctgaagt
    34381 gtcatcacgt acatgaaaat accgaccacg gcagcaacca ctaagaacaa aaagtatatc
    34441 atcgcattta aggtcatatt ttgggcagaa tagccaggaa tactttcaat gaatgtccca
    34501 atagttaata actgtagacc cttcgatgct ttttctttcg aaattttagc tgaatccttt
    34561 attacgatcc cattgatcgg ctgttcttct tcagaagcaa acggctgttg tccatacttc
    34621 aaagcagtcc acgtatctag ggacgcatag atgacgggag aaactgtgta ataagtttca
    34681 ggaaagatac cgacaatcgt caaaggatcg tcgtaactgc caattttgat cgtatctcca
    34741 attttatagc ctgaatcagc cagattttga gagatgatga tttcattctt tgttttaaat
    34801 tcatgccctt tcgtgagttt tggtaataaa aatgcttctt tcgttgtgcc gaaaactgta
    34861 acattttctt tgttttttcc tttgattgct ccgctgtaca atccgattgg tgctttctct
    34921 cctccttcaa tgtatttcag atctcctctt gttaattgtg aagctgcaaa tacttgattt
    34981 gcatcctccg acaaaacaat ctcttgtgcg tcccaatcat cgattgcttt tttaaactct
    35041 tctgaaagtc cattcgctag tcctgacaac atgaatacga catacgcaat caagaacata
    35101 ataccgacga tcaagccata tcgtaattta gaatagcgaa tttctttgat agctagaaac
    35161 atttgttttt cctccctatg atagattgat agtgacaaaa tgtcacttgt tgaatagtgt
    35221 aactctaaag tgacaatttg tcacttgtgt tgtttttttc ttatcaataa attgtctaag
    35281 acatctttcg ataaaacctt aacatgagtc ataaaaaatt tatttaagcc ttatttatgc
    35341 tttccatgat aaactaaagt gaccaaatca atgaggtggg aaaatgatta aactattagt
    35401 agtagaagac gataaagtat tatccaataa tataaaagaa atactcgctg caatcggcga
    35461 gataacacaa gtttatgatg gtagtgaagg actgttcgag ttggaaagtg gagtttatga
    35521 tcttgcaatc ttggatttga tgatgccgga aatgaatgga tatgaagtgt tagcaaaaat
    35581 acggaaagaa aaaatacaga ctccagtatt gattttgact gcaaaagata gtttggaaga
    35641 taagattgaa ggatttgaac gaggtgcaga tgattatcta acaaaacctt tctatcgaga
    35701 agaactgatc atgcgcgtga aagcattatt gaaacgctcg ctaggtctct ttgatgaaaa
    35761 tgttctgaag tataaggata tcagttgtga tttaaaaagc aatgaagtct tgtataaaga
    35821 acaagttttg cccatacaag gaaaagagtt tgaattgctc gtttattttt tacaaaataa
    35881 gggaatcatt ttgacaaaag agcagatatt tgaccggatc tggggatttg attctgatac
    35941 gacgattaca gttattgaag tttatatgag caacttacga aaacatctgc gaagtactgg
    36001 attggataaa gaaatcaaaa ccttacgtaa tgtcggttat atactgcaaa gggtgtgatg
    36061 caatgaatgg agatattaca cgaaagcaac gtagtcgctt ttttgcgaca aatgtagcag
    36121 catttgcttt tatctttttt cttttgggat tcattacttt acagatatta aaccaatctg
    36181 catacagaga aacagatctg tcattagaga aaataaattt tgattctcga acagtacaat
    36241 tagagataca aagatatcag caaggcgatc cctttttaaa cccgactcaa acggaacaaa
    36301 acagaacaaa catggaacag ccattaatgg aaccatcaaa tgaccgtttt aacactcaag
    36361 tgatcttgtg gtctaaaaat ggtgagatat tgaataaagc agctattggt gggcgtttca
    36421 accaaatcaa agaattaaaa atggatacga aaaatctgaa taccatccaa aatattgaat
    36481 taaatgaaga cagtggctca tctgccctct ctttccgttc gattacgaaa aaagcggaga
    36541 cgaatcaaga tggcgttgcc tacatccaaa ttttagaaaa tacaaatcaa atcaagaatt
    36601 cattagcgac ttttcgcacg attatgattt tgtgtatgat tgttttttgg attctctcta
    36661 ttggtatcag ttattacttg tctagtctaa gcatgcgccc tattattctt tcttggagaa
    36721 gacaaaaaga atttgttgag aatgcttctc atgaattgcg cacaccgtta acgattattc
    36781 aaaatagttt ggaacatctt tttaccaagc ctaatcatac tattattgaa gaatccgaaa
    36841 gcatcgctca agcattgtca gagacgaggc gcctcactgg attgacttcg gatttgctga
    36901 caatcgctcg gaatgattct gatcagcagc tgctttcaaa gcaaatgatc aatacacaag
    36961 aatatatcga acaacttgtt aaaccatttc aagagatggc catcatagat ggaaaagagt
    37021 ttattctcca taacgatgca acattagaag taccaattga tgaaaaaaaa atccatcaag
    37081 ttttggttat tttgctggat aatgcattaa aatatacgaa tccagaagat aagatcattt
    37141 tggattcatc tgttaaccat aaagaatggc tgattcacgt aaagaatact ggcccttcta
    37201 tcagtgaaga agatcaagca aggatttttg atcgatttta tcgggaagat caatctcggg
    37261 cgaaagagac tggcggatac gggcttggct tggcaattgc aaaacaggta atcgaacagc
    37321 atcatggaca gatttctgta tccaattatc ttccacaagg agtcgatttt aaagtccaat
    37381 tgccgttgaa gcctaaaaaa taatgcttat ccctaaaaaa gggctgtgac aaaaatcttg
    37441 tcacagccct tttttgttgc gaataaacgg tgttccagaa gtagcttctt cggaaataag
    37501 ccgaaatttc tttaagctga ccacttctgt cacaacctct ttagcttacg cttacgattt
    37561 tttattgcgg tcttcaatgt gtacatcacc gcttgtgtca atatccaatt cttctcggct
    37621 aacatcttct gtcacttttt caacatcttc atgttcttct ttatgaatcc caacttcttc
    37681 acgaataact gtatgtttgc ttacatctac ttgctcttct ttgattggga tagtaatcgt
    37741 gtcatcttcc aatttttcgt ctgttccctg tgaagattga tctgttactg gtttgcgttc
    37801 gatgacgatt tcttcacgtt tgaccggtac ttctaccgtt tcagtatcgt tgaccacatg
    37861 tttgtggatg tcgacttctc cagttgtcac atcatgtgta tttacatcta atttttcttc
    37921 ttttagttga attgtatcat catctagatt tggtttgcga tcgatgtctt cagtcttgct
    37981 tgtacccatt gtatcagtct cgccaggtac gtccatcgga tcagttcctg gtgtcatatt
    38041 caatggatcc gttgtatttt gaaagcctgt cgtgccacct acgtccattg gatctgttcc
    38101 agtgccagtt tctaatccag tccccattgt gcttgctggg ctaacagtat cttgtgtatc
    38161 cattgtatct tctgttgttt ctggctgacg atagcctttt actgtgatga caaattttcc
    38221 atcagaaata tctcctctat attgatataa aggatcattt tctggtgtag ccgtctcaga
    38281 atcataggta tcaaaagaaa aagtatcttt tattttttcc cataaagaac ggtcttcttc
    38341 accatccatc cgattttcat ctgtttcaac atctatacca gacaatccgt caaatcctag
    38401 tctagatgct gcttcatcag tagtataaat aacgatatca tctcgttcat acccttcgtt
    38461 acgcaaccgt tcaattactg ataatgcttc ttccctcgta ctatagcttc cgatgaccgt
    38521 taaatttttc tcttccatgt aaattcctcc tagcaaatag atttatgatt ggtatattgt
    38581 tacttataaa tttattctat aggagacgat tgttttctac aaatatttag attggaattt
    38641 gattaaaaca atttaattga aatttgaaaa catttatgtt aatgaaagtc atattctaat
    38701 aaaatgtcat ttgtttctat atgaattttt atgaaaaatt tcatataatt tccactcgtt
    38761 gtgatggttt aatttatcca atccatcaat aagcaaacaa cttatataaa aaaggattaa
    38821 ttctcaatat aattgctcct accatagaat aaatcttcat gtaaagtaat gaagtaccaa
    38881 ctatttctaa tacttcttta agaattatcc caacaatatc gttagacaaa ccattattga
    38941 ataaatggag agccaatcga ttctgaaaaa atgttttcta atttttcgga aataaaagaa
    39001 agagcctcct gccattagaa cgaaccaaat ccatttcatt gctcatgaag taaccacata
    39061 gctaaaaaga ggataaatca attaaaagat caaaagaatg actgcactaa taaaataact
    39121 aaaaatgtat cttcttactt catatctttt agctagtact tagttaaaaa tttgcttcct
    39181 aagatcaaga caaactgtct atcttcattt gatgaaatgc ggtaaaatat agaaaatgaa
    39241 cactattgga gggaatttgt aatggacagc aaaactagaa aacaactgca agaaaagtta
    39301 aagcaacgta cacacttgct cccttccgtc tttcaacagt ttttagaaga aaatcgttct
    39361 tccctttcat taggcagtcg ctatgaatac gcaaaagatt ttcatctgtt tactgattat
    39421 ttgagaaaag tattttctga agaagtggat gatcagctga ttatccattt agaaaaacaa
    39481 gattatcaga atttcttagc taaaatctat cgacatactc gttcgttcca aactacagcg
    39541 aaccaagaaa cggagcaatt gtttgaaaat agctattacg ggatttcaag gaagcaatat
    39601 tcattaaatc attttttacg atttttgtat caaaaaggac tgattgaaga agagatttct
    39661 cttttgggta caagtttacc ggaaacaacc aaagcagctc cgcgatatat cgatgcagaa
    39721 cttttcaaag attttgagca tttgtttatc ccgattgaag gctttcaaac aagcagagaa
    39781 gctagctttg aagaaaagaa tagaccgagg aaccttgcaa ttactgccat tcttctgtat
    39841 tgcggattaa agatccatga agtagtagaa cttaaacgta aagatgtatc tttgaccaag
    39901 cagattctta atctgaatag aaaagaaaac agactgaata aagtaccaat accaaaagaa
    39961 gcgatgccat ttctggagaa ctattttaag ttaacagcac aaaatacgga cgaaaattct
    40021 tttgtttttc gttcctcaca tgatcagcaa atttctcctc ggactattcg ccaaattttg
    40081 agcaaaatta cagtatataa aaacgtatcg ccagaactat gcagaaaaac atatcgttat
    40141 tatgcagaac tatatttaga tgatgctgac gcggtaaatt atttatgtgg taatcgatac
    40201 ctctcatccc attcttttca agatatctgg gaaaagatgg ttgatttttc ttatcacgaa
    40261 ttagcggcat tcgttcgggt ttcttccata taaaacaaat gtatgatctt tttttcacaa
    40321 taaactatgt tattatataa aggattatgt tacgattatc ttgaatttgt atattactta
    40381 acaaaagata atggagtgtg aatgatggag accataacgt attccccttt gaacttattt
    40441 acgaattttc aagaagctgc agctaacttt tccgagaccc cgattatctt tgatgagcca
    40501 ctttcagctt tcccagaatt aggacttgaa acaacttaca aaaaatgctg cgaaagtgtg
    40561 ttgaaacggg cttatcaatt ggctcatctt ggagtgaaat ccggagacaa agttattatt
    40621 tataagagtt ccgcttttga cacatacctt ctagctgttt ctgtgtctta ccttggtgca
    40681 gtgcctgtca tgacttctta tcatctacca acaacaacaa tggaagtatt tatcgatcgt
    40741 ttagaagacc ctttcatttt atttgatgat gagacaaaaa agcgagtgag agaaatttca
    40801 aatggaacaa aatcaaaaca gattcct
//
LOCUS       DAFEEZ010000017        40121 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000017
VERSION     DAFEEZ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40121
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.017"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(243..857)
                     /locus_tag="LP245_001015"
     CDS             complement(243..857)
                     /locus_tag="LP245_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1518948.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            1307..2632
                     /locus_tag="LP245_001016"
     CDS             1307..2632
                     /locus_tag="LP245_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBL1518949.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLNIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQINEEN
                     LDKIIDKIRQKYGFTSIVHASSMLESARSITRSTLVGGHAGGNGGIKND"
     gene            2625..2975
                     /locus_tag="LP245_001017"
     CDS             2625..2975
                     /locus_tag="LP245_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518950.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIVGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            2972..3151
                     /locus_tag="LP245_001018"
     CDS             2972..3151
                     /locus_tag="LP245_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518951.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQLISMNPFLFLQIGVDTRI
                     MRVLNYYCKRNNKRK"
     gene            3163..3456
                     /locus_tag="LP245_001019"
     CDS             3163..3456
                     /locus_tag="LP245_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBL1518952.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSMNMTDVYEKLLILENEYDQFNSNQQRKVKKQID"
     gene            3682..4500
                     /locus_tag="LP245_001020"
     CDS             3682..4500
                     /locus_tag="LP245_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL1518953.1"
                     /translation="MDTFQGTTFTVGNFKGGVGKTKIVSMLAYDNAMIRNRKTLIIDL
                     DPQANLTQVIARTFGITDIKTTITNGVANGELASSIIKVNENLDLLACDTSFRSFSAF
                     ANKHENELDQVTVLKKLLLPIKNNYQEIFIDVPPTISEFSDNAMAASDYSIISFQTAE
                     ESLEGVNKYVNYQKFMVDRYDLDLQIIDIVPCMVEPNDDFDEEILEEAIEKYGTVVSK
                     NLIHYQKRLRRYSKIGIHLRKYKNGNFDQWDYKAHQVFINILAELDARQEFLNK"
     gene            4519..4926
                     /locus_tag="LP245_001021"
     CDS             4519..4926
                     /locus_tag="LP245_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518954.1"
                     /translation="MPKDFDIPKMMENGEFEPLLPNNKRQDVKISGEYNFSNSALSNT
                     RNITLKKRGRPVSIPDKRNKVSVPKKISPALNSKLSILQDYMTELQSEKGRISFEKIV
                     NTLADSYIQHRLGVAKEEHIREEIQEEFEKLPK"
     gene            5246..6331
                     /locus_tag="LP245_001022"
     CDS             5246..6331
                     /locus_tag="LP245_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL1518955.1"
                     /translation="MSTENQSQKMIIKNWGYKATNVYIEKYYKFPSFLIQNSKYSKMK
                     DSSKIAYMLFKNEFRRALHEKWIDDDGLLYLEFTQADLMDKLNCYQGKVKTILNELET
                     YNLISVVKGEFNPKTKKNEKNKYYLLQPEISADDLFIQNSFDDDLSETIVKSTSSRNA
                     EIARREETAKTLDNTGNAEIARREKTAETLDNTGNAEIAQDYYINKSLDTKRHLKDTE
                     TDQLQNQVLLDNFVEIMKEDSINTFVPEKVLSLIKTFSNTYEEAQQTVTTIHKAKHKA
                     EELEKTVVVYEELESYGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFIEK
                     AIAAKLANEQRETFNELPTVSTENWLE"
     gene            7168..7500
                     /locus_tag="LP245_001023"
     CDS             7168..7500
                     /locus_tag="LP245_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBL1518956.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            8091..8420
                     /locus_tag="LP245_001024"
     CDS             8091..8420
                     /locus_tag="LP245_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518957.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDIATIIEGIYYGEVDEEISSTKDLLDFLDKNKDTFIVLTDYEE
                     VTTNEKL"
     gene            8407..8748
                     /locus_tag="LP245_001025"
     CDS             8407..8748
                     /locus_tag="LP245_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBL1518958.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLTDDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            8862..9101
                     /locus_tag="LP245_001026"
     CDS             8862..9101
                     /locus_tag="LP245_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518959.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            9168..9407
                     /locus_tag="LP245_001027"
     CDS             9168..9407
                     /locus_tag="LP245_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518960.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKMMKQKHLKRLSVMQYINDMKIT
                     GKEKACLLGSMKNFEQLRRTYVKTGSNCQLLLEVS"
     gene            9534..10223
                     /locus_tag="LP245_001028"
     CDS             9534..10223
                     /locus_tag="LP245_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HBL1518961.1"
                     /translation="MNKNNKTLFNPYVGVIIVFLLFSYFAYQGYQKDKIAEKVDGVTK
                     TIHIQEQAKTYQDNLTSLTDISKRQLITNQKQALEKDLKGEIAGKLVFSSTGFILPVF
                     QGANSDTLSLGVASTYYLDTEMGNGNYILAGYNVDTPSVLLSDMTDLSEGEEIDLIDA
                     HYKYQYEVSKRGKISDYSQVVQSKENNSFLSLPKAGKKPLLTLLAFQANNMKKCDVIQ
                     CELVNVEKINK"
     gene            10229..11395
                     /locus_tag="LP245_001029"
     CDS             10229..11395
                     /locus_tag="LP245_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBL1518962.1"
                     /translation="MSHIQELVEKLINKMSAIFLLLLVSILYLIWTVGLNPPTILFIY
                     DNAAQLVTFFVGCLFLLNLYKVKRNDLFFIAAGILFYLFFSFFRSYRGDTFYGDLIVP
                     TIIAIILIVKWTKFTVIDRSLYLVVFYVFLLVTVYRVFTEIPVPEGQSIWNPSNKLSD
                     IWINTNTIGSSLMTLALLITGFASSFGKWYMRLLSLPALILAGATIWVCQSKAALYAL
                     VIFIILEILPKKVFRNTHLSFWMYAAVSVLALPISYFAAMSDKVHLFTGREEIWRKFY
                     ETLGEKTGQIFVGMKPFFFHRGNQILGNHNTYHALVNHYGLIGFVLSIILLLSFLWLL
                     VRKRELTNGQLTFLWAFLAIMCQSFMEETLTTISWVPIVFLMLAMATHQYKTTR"
     gene            11477..12148
                     /locus_tag="LP245_001030"
     CDS             11477..12148
                     /locus_tag="LP245_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBL1518963.1"
                     /translation="MKKWLFGFLGVALIVVCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            12201..14177
                     /locus_tag="LP245_001031"
     CDS             12201..14177
                     /locus_tag="LP245_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL1518964.1"
                     /translation="MAINRYVKKAGMIVGMLGIIAGCFQGYRAYAEDVTQKTPPERVN
                     ITVHKLMYDQSTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGELVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGEEHSFQIGDAVNYQGTIHIPTDIAGGTDGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGAISAVVYFKKKA"
     gene            14190..14942
                     /locus_tag="LP245_001032"
     CDS             14190..14942
                     /locus_tag="LP245_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1518965.1"
                     /translation="MIIRHPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            14958..15719
                     /locus_tag="LP245_001033"
     CDS             14958..15719
                     /locus_tag="LP245_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518966.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLISNGETKTIDQQT
                     GVFEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            15732..15992
                     /locus_tag="LP245_001034"
     CDS             15732..15992
                     /locus_tag="LP245_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518967.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            15989..18079
                     /locus_tag="LP245_001035"
     CDS             15989..18079
                     /locus_tag="LP245_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL1518968.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLNNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTILAVSLLL
                     LVLATFGYAVLKFN"
     gene            complement(18115..20172)
                     /locus_tag="LP245_001036"
     CDS             complement(18115..20172)
                     /locus_tag="LP245_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HBL1518969.1"
                     /translation="MKLLNPKTVIAIGTFAATVALAGSADAASTNVMYRLYNPNNHEH
                     FYTSSTKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVTSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNTLDSAYKGLKKKPAPTVNKTELQALYNQVKSTAKGDFTEGSWNNFQTAL
                     SNAKKVLDDSKASQTQVNNAKNSLDSAFKGLQHKPKPSEYAVTVRHMNRQTGTLLKEE
                     HVSVKAGTSYTAKARTDLTNFEAPQYQVNGNETQTQTINTNTTFTFYYDEVFLVEVKA
                     RPNKVSDTDPNIQELYNYSKSYPVVYGQSITIEAPMFTNFVLDPRESSSNTVTLNNVT
                     SNQGINFAYTHQYNVTVNHINVDTNAVLSTETQTVYEGDSFSTSWKNMTDQNYFLCRN
                     DDSSVTVDKNGQRVINNVDQNRTITFKYKNISLSDLNNYVRQKELAWLNSYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENINSFYLYVD
                     EILSDTGAVNAMVMWKDSAAHNANLLYNNQSIVGLSHAYEVSADGSLSSDNVFISANP
                     IFK"
     gene            complement(20317..20508)
                     /locus_tag="LP245_001037"
     CDS             complement(20317..20508)
                     /locus_tag="LP245_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518970.1"
                     /translation="MYADKEKIEWLLFETGKTAYEISKHSSVAESTIADLIKKKSAIE
                     KMRFDNAAKLTKYAESISS"
     gene            20696..21151
                     /locus_tag="LP245_001038"
     CDS             20696..21151
                     /locus_tag="LP245_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518971.1"
                     /translation="MKKLIMVFTSLIAMIVILGGCGSEKNKQDSQDNGVLKPGTVWKE
                     EVGGLVHNLKIIDDTTWEYSESVWHPEQVQITVEKLKDYKGLERYKVIDSGGVDLFIG
                     KTALIVPYNKDGLETFKFIPTNEKEHRDKSEILKEYSTKSGYKLQKTSE"
     gene            21148..21390
                     /locus_tag="LP245_001039"
     CDS             21148..21390
                     /locus_tag="LP245_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HBL1518972.1"
                     /translation="MIASLFIYPEGGIAVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            21408..21710
                     /locus_tag="LP245_001040"
     CDS             21408..21710
                     /locus_tag="LP245_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518973.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQGAATSLKNNLMIFAAVAA
                     VASIVLGGIFFFFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGMFGQTPQGL"
     gene            21779..23833
                     /locus_tag="LP245_001041"
     CDS             21779..23833
                     /locus_tag="LP245_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518974.1"
                     /translation="MYFTISGNTKKDKELIKKATKKVGKRTAFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVSQVSEVEVNDEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDLVEA
                     NEEPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWERTKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCIE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMERHGQIQQELQAQIPKWKKEYEIQQQELKEQEEKQRQEEKEREQLELKKREQH
                     LAEQKVAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTAESSMENSKESDPSKAKEGSSDSTVHSNTSESSESNE
                     VK"
     gene            23833..26445
                     /locus_tag="LP245_001042"
     CDS             23833..26445
                     /locus_tag="LP245_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBL1518975.1"
                     /translation="MRIRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGSFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPENEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHKGK
                     KFHEERVKVGYRGFCEINFDCHLEQGDHVCLKYNHQGKQYVAWYEFSQKVLKDEEGKI
                     VYRKKRGETHLPELEKEAVLTLDEKKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMI
                     RKRLLLEAEKAVKE"
     gene            26442..28820
                     /locus_tag="LP245_001043"
     CDS             26442..28820
                     /locus_tag="LP245_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518976.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAVGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGFGH
                     RKDITHDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTVE
                     DLTEKAKDTLEEKLDGTRAKEFAEAVKNPSEALEKQKEKASAVKEGLKDAYGEGQVNA
                     AVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQYRY
                     KSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMK
                     DSRLNQFKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLAESGETENASVQNIV
                     TKEAAPKPINKVHNGYRPANVAFTAPTKINVTRETKNRNNELKEQLLKDIKP"
     gene            28881..29423
                     /locus_tag="LP245_001044"
     CDS             28881..29423
                     /locus_tag="LP245_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518977.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            29501..29833
                     /locus_tag="LP245_001045"
     CDS             29501..29833
                     /locus_tag="LP245_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518978.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            29834..30427
                     /locus_tag="LP245_001046"
     CDS             29834..30427
                     /locus_tag="LP245_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518979.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            30449..32473
                     /locus_tag="LP245_001047"
     CDS             30449..32473
                     /locus_tag="LP245_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBL1518980.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            32473..33672
                     /locus_tag="LP245_001048"
     CDS             32473..33672
                     /locus_tag="LP245_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBL1518981.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            33688..34332
                     /locus_tag="LP245_001049"
     CDS             33688..34332
                     /locus_tag="LP245_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518982.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPVDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            34343..35149
                     /locus_tag="LP245_001050"
     CDS             34343..35149
                     /locus_tag="LP245_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518983.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIFYIH
                     EDKVKDHVKDEDYEQHAINYKVKGYKKEQKAAQKQIESFQATIDLNEELVKKLKDQLP
                     YQVAEDQENTENKINSYQQEIETSKTQMKDQEESIQKLQEKIDRMTKENI"
     gene            35172..35401
                     /locus_tag="LP245_001051"
                     /pseudo
     CDS             35172..35401
                     /locus_tag="LP245_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            35422..36495
                     /locus_tag="LP245_001052"
     CDS             35422..36495
                     /locus_tag="LP245_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4199 domain-containing protein"
                     /protein_id="HBL1518984.1"
                     /translation="MKKTYQKFLWISYIVLFIVGFLVSVSVIVGTLFLLFSDEDLVLK
                     GLMSTLSCVMLLYLCIQINEIMPPHWQEKKKEFKEEIEIKSNDWIEYTWLPLKRNSKR
                     KEFWALQLWPIGKLFIYMASLMVTLIGYLVVVYGVAYYLLSEPKQIAASNIFTAVMTL
                     MCVMCFSIFSYLLVQFIRQNLTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIK
                     NFLTTIDQFINGYMYLFEVGFILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVD
                     FGKYEELIHTDIVHTSIHEVTVKGIRSTLKDGQETKTIDRRKEVYNFYKVEASLRYGI
                     GKLRLDGSNIQQNKPYVLGKVVI"
     gene            36539..36808
                     /locus_tag="LP245_001053"
     CDS             36539..36808
                     /locus_tag="LP245_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518985.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            37084..37359
                     /locus_tag="LP245_001054"
     CDS             37084..37359
                     /locus_tag="LP245_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518986.1"
                     /translation="MEVKIRDIDEKTIQRIDRRCIELSERTGTKWSRNRYLKVLIEND
                     FDHELMDHRKDQFDRLLEKFVDIQTYNTKILEEYIATNNQLIALLIE"
     gene            37401..37823
                     /locus_tag="LP245_001055"
     CDS             37401..37823
                     /locus_tag="LP245_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518987.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKPINESVHARVDPFDPTKFLKR"
     gene            37843..39435
                     /locus_tag="LP245_001056"
     CDS             37843..39435
                     /locus_tag="LP245_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518988.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPDE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKSLKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIESMD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            39456..39791
                     /locus_tag="LP245_001057"
     CDS             39456..39791
                     /locus_tag="LP245_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518989.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYSATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            39937..>40121
                     /locus_tag="LP245_001058"
     CDS             39937..>40121
                     /locus_tag="LP245_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518990.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT        14465 a         6158 c         8003 g        11495 t
ORIGIN      
        1 cgtcgcagaa acaacaagac tcttgatatt cttaatgctc ttcgattcca catttgtgat
       61 gaaaatgttt ttatctttga ttccaagtag tagtttgata tgatgaagat caggcataca
      121 gaacgctcct ttgattgtgt tgtggtgatt caattctaac ggagcttctg tatgttttgt
      181 tttttcatgc tcaaaaggga ccgatagaat gattttctat cagtcctaga aattatagag
      241 ccctattcgt gattgaccat gctgtctttt tttattctat atacggtttg tctcgtaaca
      301 ttgtagtctt ttgcaatctt agcgatcgca acaccttttt ttagatcctc aacgatgttt
      361 ttataaacaa gacgacgttg gggatctttt gcattggcac tgtatagctt aggacgtcct
      421 ttataaacac cgttcgcttt tgcaatctta atgccttgtg cctgacgtcg tttagattcg
      481 gtacgttctt gttcagcgat catggccaaa atttgaatga tcaaatcttt aatgaattta
      541 tccaggagag gattgccaat tgcttcggcc atgatcggta gacttgtgat gatcagctgc
      601 acatttttct tcttcaagta attgactgaa gcgatgatct cgtcgtaatt tcttccaagt
      661 cgatcaatag cttccacaat aaaaatatct tgatctcgga cgaaatccag tgcttcttga
      721 aaaacaggtc gatgagtaat cgttgcgcca gattgtttct caatgaaaat tctctctgca
      781 ccgaattttt tcatttcttc aatctgccgt tgttcatttt gatcgatgga tgagacacgt
      841 atgtatgcaa ctctcaaaat ttttacctac tttctgcaac tatttaaaaa acaccctaat
      901 catacacgag aaaaccagat ttttcaatgt cgcggtcgtg tctagttagg gtatacctta
      961 tatagacaaa aactaatgat ggaggaaata gtatgagaat tttttgtaag tgtctactga
     1021 taacttattc tcaaatgttg taaggatttt attcatttgt taatattaaa gaacggaact
     1081 ccaaaaaagt ccgtactcta atttgcagtc tctcactctt ttagagtgag agtttttatt
     1141 agattttcaa attaattagt aaagtgatag aataaattga tcatacaaat caaaagaaga
     1201 agcagggtga tagcatacct atgcttcttt ttttatgtat ttagctattt cttctttaca
     1261 atatcgaaca tatgtttgta taatgtgaaa gaatggagtg ttatttatga tggattattc
     1321 aaaagagcca gtaaatgatt actttttaat cgatatgaaa agcttttacg caagtgtcga
     1381 atgtatagaa agaaatttag atccattaac aacagaactt gttgttatga gtcgagctga
     1441 taatactggt tcaggattga tattagcttc ttctcctgaa gcaaaaaagc ggtatggtat
     1501 tacaaatgtg agtagaccac gtgacttacc acaaccattt cctaaaacac tacacgttgt
     1561 tccaccacgt atgaacctat atatcaagcg aaatatgcag gtaaataata ttttcagaag
     1621 atatgtggct gatgaagatc tactgattta ctcgatcgat gaatcaatct taaaagtgac
     1681 ccgatcactg aatcttttta cgactgaagg aacacgaagt caacggagaa agaagctggc
     1741 tcaaatgatc caggagaata ttaaagaaga gctaggattg attgctacag taggtgtcgg
     1801 agataatccc cttttggcta aactagcctt agacaacgaa gcaaagcata atgaaggatt
     1861 tgttgcggaa tggacgtacg aaaacgttcc tgaaaaagta tggaatattc ctgaaatgac
     1921 ggacttttgg ggaattggct ctcgaatgaa aaaaagactc aatcagatgg ggattatgag
     1981 cattagagat cttgctaact ggaatcctta tacgattaag aatagactag gtgtgattgg
     2041 cttacagctg tacttccatg ctaacggaat cgatcgaaca gatatagcaa tcccgccaga
     2101 accgacaaag gaaaaatctt atggtaattc acaagtgtta ccacgagatt atactagaag
     2161 aaatgaaatc gagctggtgg taaaagaaat ggcggaacaa gtagccattc gtatcaggca
     2221 gcataattgt aaaacaggat gtgttcattt aaacattggt acgtcgatct tagaaacgag
     2281 accaggattt tcacaccaga tgaaaatacc tatcacagat aatacaaagg aattgcagaa
     2341 ttattgtctt ttcttgtttg ataagtatta tgaaggacaa gaagtaaggc acgttggaat
     2401 aacctatagc aagcttgtgt acaccgattc gcttcagctg gatttattta gtgatccaca
     2461 aaagcaaatt aacgaagaaa atttagataa aattattgac aagattcggc aaaaatatgg
     2521 ttttacgtcg attgtacatg cttcttcaat gttagaaagc gctagaagca ttactagaag
     2581 cacacttgtt ggtggtcatg cgggcggaaa tgggggaatt aaaaatgatt gattacaatg
     2641 atcgtggacg tttaaagtgg gcagggtttt atttatctga tcatactgaa gaaattgatg
     2701 ccgacaatga acaacgaacc agtcaaaatt tagcaaaaga acaaatgacg actgaagaga
     2761 ttgcggaagt attgaacgct gcagtcataa aaaatagatc agtatctatt caaaaagaag
     2821 aacgaaacgc tgaaggatac tatccagaag atattgttgg caagatctta ggtagtgatg
     2881 agctggggat ctacgttgga aaagacaaaa ttcactacga cgaaatacgt catatcgaat
     2941 tttaccagga taataaatgg agtcgattag aatgaacatt atccagcaat atgagctaaa
     3001 gtatataacc tttgatcagc tatcagaaga gatttggggt tatggccaac ttatctctat
     3061 gaatcctttt ttgtttttac aaataggagt agatactaga ataatgcgtg tgttaaacta
     3121 ttattgcaaa cgcaataata aaagaaagta ggcttacgca ccatgtctat caatacattt
     3181 gtttactcgc acccgatcaa tgtttacatt atcaagaatt taggaatcac tgtagaacaa
     3241 ttttgtgagt tatatgccta cccacaagga acggttgcaa gctggataac ccgacaacgt
     3301 agaataaaat cattacctgc ttcatttgta tatgatctaa gtcttgcttc tagtatgaat
     3361 atgaccgatg tatacgaaaa gttattaata ctagaaaatg aatatgatca attcaattca
     3421 aatcagcagc gaaaagtaaa gaaacagata gactagaata gctattttcg aaaagcaata
     3481 tttaaggtat aagttatacc tttaataata aaagtataag ttataccata aatatatatg
     3541 gtataactta tacttttatt attaaaaacc gctatatcca aacgttttta gatattatta
     3601 tttaagttat acttttaatg ttgaccattt ccgatatata agttatactt taattatcaa
     3661 ttaaagattg ggaggattta catggatact tttcaaggga ctacatttac agttggcaat
     3721 tttaaaggag gagtaggtaa aactaagata gtcagcatgc ttgcttatga caatgcaatg
     3781 ataagaaata gaaaaacgct tattattgat ttagaccctc aagcgaactt aacacaagtc
     3841 atagcaagaa ctttcggtat aaccgatatc aaaaccacta taacaaatgg tgtcgcaaat
     3901 ggagaattag caagtagtat tattaaggta aatgaaaatc ttgaccttct ggcatgtgac
     3961 actagttttc gatcattctc cgcttttgct aataaacatg aaaatgaatt agaccaagtt
     4021 actgtcttga aaaaattact tcttccaata aagaacaatt atcaagaaat atttattgat
     4081 gtaccaccaa ccattagcga attttccgat aatgctatgg cagcttcaga ctattcgata
     4141 atttcatttc aaacagctga agaatcctta gagggagtca acaaatatgt aaattatcaa
     4201 aaattcatgg tcgatagata cgatcttgat ttgcaaatta tagatattgt accttgtatg
     4261 gtagaaccaa atgatgattt tgatgaagaa atcctagaag aagcaattga aaaatacgga
     4321 accgtggtat ccaaaaatct cattcattat caaaaaagat tgagaaggta ttctaaaatt
     4381 ggtatacatt taagaaaata caaaaatgga aattttgatc aatgggatta taaagcacac
     4441 caagtattta taaatatttt ggcagaacta gatgctagac aagagttttt aaataaataa
     4501 taaggagttg cataagtaat gcctaaagat tttgatattc ctaaaatgat ggagaatggt
     4561 gaatttgagc cattattacc caataacaaa cgccaagatg tgaaaataag cggtgaatat
     4621 aactttagca atagtgcatt gagtaacaca agaaatatta cattgaaaaa aagaggccga
     4681 ccagtttcaa ttcctgataa aagaaacaag gtatcagttc ctaaaaagat ctctccggca
     4741 ttaaatagca aactctcaat tttacaagac tatatgacgg agttacaaag tgaaaaaggg
     4801 agaatttctt tcgaaaaaat tgttaataca ttagcagact catatatcca gcatagacta
     4861 ggagtagcaa aagaagaaca cataagagaa gaaatacaag aagagtttga aaaattacca
     4921 aaataatttt ttttcatgcg gtattcaatt aaagtataag ttatactaga taaatgaata
     4981 ttaaagtata agttatacat taaatattta aggtataact taataaacaa cgtgtaaatt
     5041 tgcgattaaa tcaacattat aaaattatta tttaaagtat aagttataca ttatttgtat
     5101 ttaaagtata acttatactt atttttttaa tatataactt ataccttaaa tactgaaagt
     5161 gttttattca cccttaatac atggtatagt tcacttgttg aaaatcctga atatatacaa
     5221 gtttctaaga agaaggagaa atttaatgtc tacagaaaat caatctcaaa aaatgataat
     5281 taaaaattgg ggatataaag caacgaatgt ttatattgaa aaatattata aatttcctag
     5341 ttttttaatt cagaattcta aatactctaa aatgaaagac agctcaaaaa tagcctatat
     5401 gctttttaaa aatgaatttc gtagagcctt acatgaaaaa tggatcgacg atgatggtct
     5461 attatatttg gaatttacac aagcagacct aatggacaaa ttaaattgct accaaggcaa
     5521 agtaaaaacc attttaaacg agttagaaac atataatttg atttcagtcg taaaaggaga
     5581 atttaaccca aaaacgaaaa aaaatgaaaa aaataaatac tatttacttc aacctgaaat
     5641 aagtgccgat gatcttttta ttcaaaattc tttcgatgac gatttaagcg aaactattgt
     5701 taaatcaacc tcttctcgga atgcggaaat cgcacgtcga gaggaaactg ctaaaaccct
     5761 tgataacact ggaaatgcgg aaatcgcacg tcgagaaaaa acagctgaaa cccttgataa
     5821 cactggaaat gcggaaatcg cacaagatta ttatattaat aaatctttag acactaaaag
     5881 acacttaaaa gacactgaaa cagaccaatt acaaaatcaa gttttgctag ataacttcgt
     5941 tgaaatcatg aaagaagaca gcataaacac atttgtacca gaaaaggtat taagcttgat
     6001 aaaaacattt tctaacactt acgaagaagc ccaacaaacc gtcaccacaa tacacaaagc
     6061 aaaacataaa gccgaggaac ttgagaagac ggtagttgtg tatgaagaac ttgaatctta
     6121 cggaattgat gcggataaag gattatatat gacgttgctg aaagcttatc aaaaacaaaa
     6181 gactgagaaa gtaaataatt tgcagaattt gatttttgtg tatgtaaaaa actggtttat
     6241 tgaaaaagct attgcggcaa agcttgcaaa cgaacaaaga gaaacattta acgaattacc
     6301 aacagttagt acggaaaatt ggctagagta gttgataaaa agcgaacact ataaaaatga
     6361 tcaattttaa attagaactt ttttacaatt ttaattttat tacaaatgtt acaaataaat
     6421 agttattatt ccggagtttt tagattaaaa gtttatgaaa acaatcacaa acgtaggttt
     6481 taatgtcata atcgttagat attttagtta tttttcattc aaaaaaacag ggaactagtg
     6541 tttgcatatg tatttttttg agttataata attcatgaag agaggtaatt cacttattta
     6601 cccaagctga aaagcctgat attacttctt ttcaggcagt gctgctaata ttcaattaca
     6661 cttttttgta taaatttagt tgttttaaat ttaattgtct gctatgcttg tgatgaattg
     6721 attttcgttc tgcacttttg gacgataaat ttggacaatt gaaaatacaa aaaaaagaaa
     6781 ggccctgtga gactcggaag gctaccaacc ttcgtcgacg tccacaggtg gcattaagtc
     6841 tatacccctt aatgcgttta cctttcagtg ttacggtatt acccgtaacg gatttagtat
     6901 aacagatatt caaaagtgat accacttttt ttggctgtgt taaggttaaa aatacgtgat
     6961 attacgatga atctatgcct aagcataatg ttataaaaat gtccgtgggg ctctttgccg
     7021 tatgacgaac gctgaaatta gagggaacgc atgtttgaat gcgttccctc ttttttgttt
     7081 gtcatgaacg aaaatcaatt ctctattttt gaaaaataac aagaaaaact tgttaaaaat
     7141 atttaaagta agtgggtgga ttattttatg tcatatacag gaattttgag tctcgaagat
     7201 atttgtcact acggtaaacg gtgtaccgct acagaaaaga tcacgaagaa actatcaact
     7261 ggtcaaagta aaaccgttgt gcagtgtaag aaatatataa tccagaaaga caaagtctca
     7321 gaagaaatga tttattacat tgggaaacaa aaacaaataa ttttaaaaga tcctatccct
     7381 ttaaaagagc tatatccaac aatcaaacat gtttatgacc aaaacggtgt actgattggt
     7441 cgaagaaaaa atggagtctt gcgttgtacc gcaaaaggga tggggcgttt aatcagctga
     7501 attgatcatt ctcataactt gtattttatc gtttttcgct tgcttgaaaa tattgtcgag
     7561 acttctaaag gaacttagaa tcactagaaa aataaggagt agacttgatc tatcaacaat
     7621 tcccttcggg gagtgacggg gtaggttttt acgattggta acgtaaaaaa ttggtcaatc
     7681 gagtaaatgc ccttgtttgg atagtggtga aatgaatttg tgtaaataat atgcacagag
     7741 taaacaagag ggaatttaga agttagacaa gttagaatag cgcctagatt aatcatgagc
     7801 agctactaag ggatctaggc tttgacgcaa actcatggaa taaggagtag gtcttctcgt
     7861 aatggggagg acgcacaaga aattgtgtcg tgtgctgcag tacatgtaga tacttgcgag
     7921 gacgttgatc attggatcaa tcgagcattt accgctgtct actagggttt ctcgtttcgg
     7981 acgccataaa cgagtcgatt tattttatat atttttgagt gaacgaaaaa cgataaagat
     8041 attcgttatg aagtaaaact aatttagtag atagcaaagg tggtagagga atgattcaaa
     8101 aatttgcgaa aatgagtaaa actgcatgga ttgaaaagct tgaaaatgac ttgagtgtca
     8161 tgcgattagc tccaaagaaa ttcaaacgag agattgcaga aaaagaagca attttgtcgg
     8221 tattgaatgc ggtagacgat aaatgtccag taaaaattag tttttcagat atagcaacaa
     8281 ttatcgaagg tatttattat ggtgaagttg atgaagagat atcttctaca aaagatttat
     8341 tagatttttt ggataaaaac aaagatacct ttatagtact aactgattat gaggaggtta
     8401 caacaaatga aaaattatga tccgaatata cgattgggca cacatacgat taaggtttct
     8461 ttccaacgtt gggattacaa aggatttgtg acgtttagaa gaggcggaaa ttgtaaagga
     8521 ttagatgttt tagcattaga cgaggatgat ttatacgatc aaacattgac tgataatcca
     8581 attggattcg gcttgctacc tgaagatgat gaaggtaatg aatggtttaa aatgacgctt
     8641 acggatgata atggagacga attatctgtt gaagatactt ggtcatattt gagtgattat
     8701 attgtcagcg ttgaaatcat tgaatttgta gcggataaag aagaataaaa actggaggaa
     8761 taaattttac agataaaggc ttagaaggag tcacgacgaa taataaaaag gtagtattac
     8821 cttaggcatt gagtaaggaa tttatttagg aggaaaatta gatggcgcga ccagttttag
     8881 aggcgatgga tatggatact ttgacaaaag gaaggtatgt acagctgtta gctcgtggtt
     8941 attcacctaa agatgtattc aaatccctgt ctaaaggaac agatatggaa aaagaaagat
     9001 tacgaaaaga attcgattat tggagaaccc ataatggaat caaggatttg aaaccagcac
     9061 ggccagtaat taaacgaaag aaaaagataa cccaagactg aagtgtagag cgtatgtgat
     9121 cataggcttt tttatttttg caaaaaacaa gaaaggtagg aaaactcatg aattatgaag
     9181 aaatcgaaaa cagaaaaaaa gtgtcgaaag aaatggaaga aaagttgcta aaaatgatga
     9241 aacaaaaaca ccttaaaaga ttatctgtca tgcaatatat caatgatatg aagataacag
     9301 gaaaagagaa agcttgtttg ttaggttcaa tgaaaaactt tgaacagttg aggcgaactt
     9361 atgtaaaaac aggttccaat tgccaactat tattagaagt ttcttgacga ttatgatatg
     9421 aaaatgatca attatgatgt ggcattgtta ttgaataaaa agaatagtaa aatttaacat
     9481 ggtttatctt ggttagatgt aggtaaatta attcatatat agaaggtaga tagatgaata
     9541 aaaacaataa aactttattt aatccttacg tgggcgtaat cattgttttt cttcttttta
     9601 gttattttgc ttatcaaggt tatcaaaagg acaaaatcgc tgaaaaagta gatggtgtaa
     9661 caaaaacaat ccatattcag gaacaggcta aaacctatca agataattta accagtttaa
     9721 cggatatttc taagagacaa ctgattacta atcaaaaaca ggcattagaa aaggatctca
     9781 aaggtgaaat tgctggaaaa cttgtttttt cttctacagg atttattctc cctgtttttc
     9841 aaggagcgaa tagcgacacg cttagtttag gagtagcttc tacttattat ctagatactg
     9901 aaatgggaaa tggaaattat attcttgctg gttataacgt agatacacca agcgttttat
     9961 tatccgatat gactgattta tctgaaggag aagaaattga tctaatcgat gctcattaca
    10021 agtatcagta tgaagtctcc aaaagaggaa aaatttctga ttacagccag gtagttcaat
    10081 ctaaggaaaa caattccttt ttatccttgc caaaagcagg taaaaaacca ctactcacac
    10141 tgttagcctt tcaagcaaat aatatgaaaa agtgcgatgt gatccagtgt gaattagtca
    10201 atgtagaaaa aatcaataaa taagggaagt gagtcacatt caagaacttg tagaaaaatt
    10261 gatcaataaa atgagtgcca tttttctgtt actgttggta tccattctat atttaatatg
    10321 gacggtgggg ttaaatcctc ctacgatatt atttatttat gataatgctg cacagttagt
    10381 gacgtttttc gtaggctgtt tgtttctttt gaatctgtac aaggtaaaga gaaacgatct
    10441 attcttcatt gcagcaggca ttctttttta ccttttcttt tcttttttta gaagctaccg
    10501 aggagatact ttctatggtg atctgatcgt tccgacaatt attgctatta ttttgattgt
    10561 aaaatggacg aaatttactg taattgatcg tagcttgtat cttgtagtat tctatgtctt
    10621 tttactcgta acggtttatc gagtatttac tgagatacca gtaccagaag gacaaagtat
    10681 ttggaatcca tcgaacaaat tatcagatat ttggatcaat acaaatacga taggtagttc
    10741 tttaatgaca ttagcccttc ttatcacagg atttgctagt tcatttggaa aatggtacat
    10801 gcgattgcta tcattaccag cgttgattct tgctggggca acgatttggg tttgccaatc
    10861 gaaagcagca ttatatgcgc ttgttatctt cattatctta gaaattttac ctaagaaggt
    10921 ttttcgaaat acacacttgt ccttttggat gtatgcagca gtttcggttc tagctttacc
    10981 gatttcttat tttgctgcaa tgtcagacaa agttcactta tttacaggac gagaagaaat
    11041 ttggcgcaaa ttctatgaaa cattaggcga aaaaacagga caaatatttg tagggatgaa
    11101 acctttcttt ttccatagag gaaatcagat tctaggtaat cataatacgt atcacgcact
    11161 cgtcaatcac tatggattga ttggttttgt tctatcgatt attcttttgc ttagtttctt
    11221 atggttgctc gtaagaaaac gtgagctgac aaatggacaa ctaacattct tgtgggcttt
    11281 tttagcgatc atgtgtcaat cgttcatgga agaaacatta acgacaatca gttgggtgcc
    11341 aattgtattc ttaatgttag caatggctac acaccaatat aaaaccacca gataaatgaa
    11401 atagaatagt aataagagaa aacacttttt cgttgtgaaa aagtgttttt tgttttgtct
    11461 gaaaggaggc agatggatga aaaaatggtt atttggtttt ttaggagtcg ctttaatcgt
    11521 cgtttgcagt gtgtttggct atgttagcta ccaaaaacat gaaggagagg tgtttaagca
    11581 aaatatagaa aaaaagatgc ccgtagatca aatcaatgca cacgcaaaga gttataagga
    11641 ggatgcaacg aacgtcaata atgatatgtc tttggggcaa atgttgtcca tacaaaaaga
    11701 agcaatcgaa atgggcgtca ataaacaagt atttgcacaa attcagattc ctgcacttgg
    11761 tttagcattg ccaattttta aaggggcaaa tcaatacact ttgagtcttg gagcggctac
    11821 ttatttttat gaagatgccg aaatgggtaa aggaaactat gtcctagcag gtcataacat
    11881 ggaaatgcca ggtgttttat tttctgatat tcaaaagttg tcattagggg aggtgatgga
    11941 cttagttagt aacgatggcg tctatcgtta caaggtaacg cgtaaattta tcgtacctga
    12001 gtactttaaa ttaatcgatg gcgttcctga agagaactct ttcttgtctt taccaaagaa
    12061 aggagagaaa cccttattaa cgttgtttac ttgtgtttat acgtcacaag gaaaagaaag
    12121 atacgtggta cagggagagc tacaataaca agaatttaat caacgcgagt cgttgaaata
    12181 tgaaatgagg agagtaaaaa atggcaataa atcggtatgt aaaaaaagct ggaatgattg
    12241 ttggaatgtt aggaatcatt gcaggctgct ttcaggggta tcgagcttat gcagaagatg
    12301 tcacgcaaaa aacgccacca gaaagggtca atatcacggt tcataaatta atgtacgatc
    12361 aaagtacgca attgaacgtt gatattgacg gaatcaaaaa tgatggttat acgcacgatc
    12421 aatatcctac aggtgtaacg aaatacaaca aggcagatta tggtgatgtt gagtttacgt
    12481 taggaaatat tacggatcaa gtattaccga ctgaagattc tgatctaacc aacgcgaaag
    12541 tggacgaaat cgttaaagat gtagaagaca agggatctaa cagtgagtac gttaagaatg
    12601 caaccaataa aattacttca gctgtagatg aaaatggtga gatcactttt gctgatcaac
    12661 cagcctatgt caattccaaa gggaatgtat atgtggttta tgaaagtaaa tccgctgctg
    12721 gattagtcac acaaaaagca aaaccaatgg ttgtgattgc gccaatgaca gacaacacag
    12781 gatcaggatt tttaaaagat attcatttgt atccaaagaa cattgtttct aagttgagtt
    12841 ttgaattaac gaaatttggt gacgatggca cagctcaaag caaacaaaca cctttaaaag
    12901 gggcaaaatt tgagttatac aagggcgaac ctggaaaagg aacaaaatta ggagagcttg
    12961 tatcggatga tcaaggaaag ctgactgcaa ctgatttgac gttaggaaaa tactactttg
    13021 tggaagttcc ttcagaagtt gtagttggat cagatcaaga accaacagca gaccaatatt
    13081 tgttaggcgc agacgctcgc aacgatgcgc acaataagtt aacctttgaa attacgaatg
    13141 acggcgtgac aagtgattta aaagcttcct acgtgaacta taaagcacca gtgatcgata
    13201 aaacagtgac aaatggaaca ggagaagaac attctttcca aattggtgac gcagtgaatt
    13261 atcaaggtac aattcatatc cctacagata tcgcaggtgg aacagatggg attacagtaa
    13321 atggtgtaaa aagtgaaact tctccttaca gtgtatttaa atggggcgac acagcaggta
    13381 aaggactttc ttatgttgct gaaaaagcag atattaaagt aacaaataat gatggttcag
    13441 tcgtattaaa agaaaatact gactataaaa tcgaaaattc tgatagtggt tttgtgatcg
    13501 attttatcgt aaataatgga caagtaagtg atacagttgc gaatttacat ggtcaagatc
    13561 taaaaatgac ttataacatg tttgtgaatg atagtgctga aatcgcaaat ccattaacaa
    13621 atagcgtgga tttcgtttat aacaataatc catttaatca ggaagaacac cacgaaaaaa
    13681 cgaaagctga cgttgtgact tatggcgcaa aattcttaaa agtcgatagc ggcctatttg
    13741 gaacaggtat caaagcaaca ccgcttgaag gcgcagaatt tgcagctaag aatgcagaag
    13801 gtaagtacta cggtggactt actgatacag ataaagatgg tgtcaaagaa gcagtttggg
    13861 tagacgatgt agcaaatgca gcaatcctaa aatcagataa agagggtcat tttgaaatca
    13921 ctggtttaac tgaaggagat tactcactgg aagaaacaaa agctcctgaa aactatcaaa
    13981 aattaacaaa agagatctct ttcaaagtag acaaagattc atacaaagaa gaaaaccgaa
    14041 tcacgatcaa aaataatcaa aaagcttccg taccaatgac tggtagcaac ggtttccaat
    14101 cttacgtatt gatctcttgc ttgttgcttg gggcaggcgc aatttctgca gttgtttact
    14161 ttaagaagaa agcctagaag gatcagctaa tgattatcag acaccctaag aaaaagcgaa
    14221 tcatgggtaa atggatcatt gctttctggt tactttcagc tgttggtgtc ttacttttga
    14281 tgcctgctga agcgagcgtg gcgaaatacc aacaaaatca gcagattgcc gcaatcgatc
    14341 gaacaggaac ggcagcagaa acggattctt ctttggatgt tgctaagatt gagttaggcg
    14401 atcctgttgg tattcttaca attccaagta tttctttaaa actaccaatt tatgacggaa
    14461 cttccgacaa aattttagag aatggtgtag ggattacgga aggaactggc gatattacag
    14521 gaggaaacgg taaaaatcct ttaatcgcag ggcacagtgg actttataaa gataatcttt
    14581 tcgatgattt gccttcagtt aaaaagggag aaaagtttta tatcaaagtt gatggtgagc
    14641 agcacgctta tcaaatcgat cggattgagg aagtgcaaaa agacgaacta caaagaaact
    14701 ttgtcactta cttagaacca aatcccaatg aagatcgagt aacgctaatg acatgtacgc
    14761 ctaaggggat caacacacac cgtttcctag tgtatgggaa gcgagtaacc tttacaaaat
    14821 cagaattaaa agatgaagaa aataagaaac aaaaattatc ttggaaatgg cttttaggaa
    14881 gtactgtttt tctttcagtc atgatcattg gttcgctatt tgtttataaa aagaaaaaat
    14941 aaaggagggt aaccaacatg agaaatagaa aatggctatt tgtttgtgca gccgctcttt
    15001 tttctttcac tgcctacaca cagttgacgt ttgcagacag acaagaaagc acggatagca
    15061 cagaacaaac aatccaaacg tcagatagca gcacgattca aagcagcgat gaaaccgtcg
    15121 attcgtcaac agttgattct tcagaagaac ctaaaattgc tgaagacgat caaatagtca
    15181 aacagaccat tcacgttcaa aaaattattt cttccgaaca attagacaac caggggcaaa
    15241 agcttgaaaa acaagaagga gtaaatggcg cgaagttttc tgtttatgat gtatcggaca
    15301 ttttacaaaa gatggatgtt aaggatctca ctactgacca aattgaatcc caattaaaag
    15361 atcgagtgaa aaaactatcc agtgatcaac tgaagctaat ttctaatgga gaaacaaaga
    15421 caattgatca acaaacaggt gtctttgaat tctcggtaga agtacaggca aatcagaaac
    15481 aagcttatta tattgtcaat gaatcaagtc ctgaaaacat ttctaatagc gaggatattt
    15541 tgctattaac acctgtttct gataaaaatg gtgaattctt aaaggatgtg tggatttatc
    15601 ctaaatcaga agcttcgcaa cctaaagaag aagtaaaaaa aatcgtatct actggcgtaa
    15661 agaaaaactt ctttgagaat tgttgggatt ttgttactca cttgttttct agagattaag
    15721 gaagaaataa aatgaaactg atcaaattat tattattcaa tttttcttgt ttaaccgcag
    15781 tctttttgta ctgcggttta ttattttcta aactatctat tttgccaagc taccaactat
    15841 acctaatgag gattttaaac ataccagctg cttccatgcc gctagatatt atggaaaagc
    15901 tcattaggaa tccattattt actacgatca atttgatcgt tattgtcgga atttcactag
    15961 tcatttataa aaaagagggg atgaagggat gaattttaaa cactcgtgga caagacggtt
    16021 aaaatatgtt tttcccataa tgatgatgtt aggtacattg tttgggttaa aaacagccaa
    16081 tgtctttgct gaaaaagtta ttgtcgatcc gtcaaatcca atccagaacg taaagaataa
    16141 ttttattatt ccaaaagatg ttcctaatgc aaaaacaaat attactgtaa acggagcgtc
    16201 aaaagtttac aaatatcatg ttgatgccaa caaaggtggt tttacagacg actacgtagg
    16261 attagtggag ggaaacaaaa atatacgcta tccttctttc caaaaagaat acggtgaaac
    16321 aaaccttgtt ttagaaggcg taacaaccaa caccaaagtc aatattgact atggaaaaat
    16381 cggtacgtat aacgggaaaa aagtcaatat caagctagtt ctatctaata ttcacttata
    16441 ctcggatacg ttgccgtgga atctactaga taacaactat acaaaaactc attttcgaga
    16501 cgatggctat aaaaatacga atggtgcaat gagtaaatct aaaaaaagaa cagtactttg
    16561 gatctcagac aatcttttct caggaattgt ttaccattca acacaaatga atgtgcagct
    16621 agtagccaca tatgaggacg gtagccccgt tcaattttca ggagatacat ttatcagttt
    16681 taactctttg aaccctgcag gaggaaaaag cacggatctt aaaggagaat atgcccacta
    16741 tgacaaaatg aatacgacag attggtatgt cagaaaagat acggttcttt cagaatttaa
    16801 atctttctac aacaatctga acgtggtagg tggccaccca ggaggaagct ctaagctgac
    16861 acaagcggat aatgatttca ataatttgca tgataaatta ggagatccga agtttggtca
    16921 aggtactgtg tcctttaaaa tatctgaagc aaatccgacg tttgtgattg gttcttctaa
    16981 tgttcaaacc tggtttactt tatcttctgc gacaatcttt agtgttgttc ctgatcaacc
    17041 tgaaaaaaca ggggttgata aaaatggaaa taacgtgaac gataaaatgt tgcaagtagg
    17101 agacacgatt caatatcgaa tcaaacagaa ggtgaatcga ttaggagtgg atttactagc
    17161 ggtttacgat cgatttgagt taatcgataa tttaccaaaa gaagtaaatt acgtcgatgc
    17221 acacgttgaa agtggtacaa ataaaaaatt cgatgtatct ggtgaagtga cctatgacaa
    17281 aacaaaacac caggtaaaat atgcagcgaa agctgataca ttaaaaaatc gaatgaagta
    17341 taacggcgaa acttacgaat tagtgatcaa tgtaaaagtc aatgaattgg ccaatcaaaa
    17401 tagtgtagcc aaaaatcagg gaacgtcgat cattaataaa gtagaaaagg atacaaatat
    17461 cattaccgtt tatttcccta aaattccagt gaaagaagta caacaaaatg gaaaagatgt
    17521 aaacggacga aatgacggta agaagggtac gccgacagct cctttaaacg caggatctga
    17581 agtacaatat ctagtcacac aaaaatggca cacaaaaggc gtagacgctg cgtcagatca
    17641 ctacaaacaa tttagtattc aagatccaat tgaagctcgt ttgacatata aagaaggttc
    17701 tgcgcaagta atagataaga gtaaaggaaa agatattact tctgaaggca cactaaccta
    17761 tgatagcaat tcaagaacgc tgaagtggga agcttccgct gacttcttaa ataacaatct
    17821 tttagatgga cgagaaattc agctgatatt tacagctaaa actccattac aatcagaaaa
    17881 aaatattgat aaccaagccg tagtagcagt agataatgtt tctaataaaa caaatgttgt
    17941 gacaattggg gttgatccta acttgccaca agttattgtt cctaaaacag gttctacaca
    18001 tttagtaacg attttagcgg tcagcttact attacttgtg ttagcaactt ttggctacgc
    18061 agttctgaag ttcaattaaa caaaaaaaca aggctgaaaa tcagccttgt ttttctattt
    18121 gaaaatggga ttggcactaa taaatacgtt gtctgaagaa agtgatccgt ctgcagaaac
    18181 ttcataagca tgggataaac caacgatact ttgattgttg taaagcaagt ttgcgttatg
    18241 agcagcgcta tctttccaca taaccatagc atttactgct cctgtatctg aaaggatctc
    18301 gtcaacgtaa aggtagaaac tattgatatt ttctccttta gcaccgtagc agcctaagct
    18361 ttctaagaga tcttggaaag taccgccgcc aggtcggtaa tgactgaagc ttacttgtaa
    18421 ttcttttgca cgaatatctg cagcttgttg aacgatatca ttgaattgca ttggggcaac
    18481 gccattttgt tgacggtagc tatttaacca agcaagttct ttttgacgca catagttgtt
    18541 taaatcactt agtgagatat ttttgtattt gaaagtgatc gttcgatttt ggtcaacatt
    18601 attgattaca cgttgtccat ttttatcaac ggtaacagat gaatcgtcat ttctacacaa
    18661 gaagtagttt tgatcggtca tatttttcca agaagtagag aaactatctc cctcgtaaac
    18721 cgtttgtgtt tcagtagata aaacagcgtt tgtgtcaacg tttatatggt tcacagtgac
    18781 gttgtattga tgagtatagg caaaattgat tccttgatta cttgtaacgt tgtttaaagt
    18841 cacagtgttg ctagagcttt ctctaggatc aagaacaaaa ttagtgaaca taggtgcttc
    18901 aattgtgatg ctttgtccat aaacgacggg ataactctta ctgtaattat agagttcttg
    18961 gatatttgga tcagtatccg agactttatt tggacgagct ttcacttcaa ctagaaagac
    19021 ttcatcatag taaaaagtaa atgtggtatt tgtgttaatc gtttgtgttt gtgtttcatt
    19081 cccatttact tgatactgtg gtgcttcaaa gttagtcaag tcggttctag cttttgcagt
    19141 gtaacttgta ccagctttta ctgagacatg ttcttctttt agcagcgttc cagtttgtcg
    19201 attcatatga cggacagtta ccgcatattc tgaaggttta ggtttgtgtt gtaacccttt
    19261 aaatgcagaa tcaagactat ttttagcatt atttacttgg gtttgagaag ctttagaatc
    19321 gtctagtact tttttagcat tggataaagc agtctgaaaa ttattccaag atccttctgt
    19381 aaaatctcct ttagcagttg attttacttg gttgtacaag gcttgtaatt ccgttttgtt
    19441 cacagtagga gctggttttt tctttaatcc cttgtaagca gaatctaatg tgtttttggc
    19501 actatccact tgtttttgag tcgcttttga gtcatttaac acttttttag cattgtttaa
    19561 agcggtttgg aatgcgttcc aggtattgtc ggtatagtca ccttttttag ttcccttaac
    19621 gctcgtataa agagcttcta aagctgattt attcactttg ggtttagagg tgtcagcacc
    19681 ataccaacca ataccttcgt atttccagcc atagtctttg gttaaccatt gtacttcttt
    19741 ccaacttgca gtgtagtgat gcgaaccaga ggtaacacct ggaaggaaaa ggcggtagat
    19801 cggtttatta tttttttcgg cagaacgcca ggcaggccct tcataagtcc aaccgtaatt
    19861 tttggtcaac catttcactt catcccaact agctgtgtaa tggtgatcac gaaggccttt
    19921 attgtataaa cgatagacaa ggtggccacc gctagtcggt gcttcccaag cggggccttc
    19981 ataattaccc cacttaattt tcactaggtg atcacgttct tttgtgctag aggtgtaaaa
    20041 atgttcatgg ttatttggat tataaaggcg atacatgacg ttagttgaag cagcgtcagc
    20101 agatccagca agagcaactg tggcagcaaa tgttccaata gctataacag tttttgggtt
    20161 taataatttc atgttttcaa ctccctatta aatgattaaa tattttgttt acattcataa
    20221 tataccacgg tataccgagg tagtcaacgg tataccgtgg aaattttgaa ataaaaaagc
    20281 cgccctatga agagtgtaag gatggctgtt tatatgctat gaagaaatgg attcggcgta
    20341 tttggttagt ttggcagcat tatcaaatcg cattttttca atcgcacttt ttttctttat
    20401 taaatccgca attgttgatt ctgcgactga agaatgtttg ctaatttcat atgctgtctt
    20461 gccagtttca aatagtaacc attcgatttt ctctttatca gcgtacattg caatgctccc
    20521 tcttgatttt ttctttatta tagctctttt ttgtaataaa tcacaatatc aagaggaaaa
    20581 gtttctatag aaaggtggga aattatgagt atccgttccc cgtgtatcaa aatgaggttt
    20641 gttgctactt tcgttattta atatactaaa ataaaacaac gaaagaagga atagaatgaa
    20701 aaagttaata atggtattta cttcgttgat tgccatgatt gttattttag gtggatgtgg
    20761 tagtgaaaaa aataagcaag atagtcaaga taatggcgtg ttaaaaccag gaacagtgtg
    20821 gaaagaagaa gtaggcggac ttgttcataa tttaaaaatt atagatgata caacatggga
    20881 atattccgaa agtgtttggc atcctgaaca agtacaaata acagttgaga agctaaaaga
    20941 ctataaagga ttagaaagat ataaggtaat cgattcaggt ggagtagatt tattcatagg
    21001 taaaacagcc ttaatagttc cctataacaa agacggttta gaaacgttta aatttattcc
    21061 aacaaacgaa aaagaacatc gagataaaag tgaaatatta aaagaataca gtactaaatc
    21121 tggatacaag ttacaaaaga ctagcgagtg attgctagtc tttttattta tcctgaagga
    21181 ggaatcgcag tggcaaaagc taaaacgcca tttgaaaaag ccgcgtctaa aatcttagaa
    21241 cgtcgcggtg tatctgaaac acagtggaaa caagaagtcc ttgaaaaagc acaatttgac
    21301 ctattacggg gaaaagacaa ggacttagaa ggatatatct atcaacgtga acgtgaaaag
    21361 cttgttttcg atgaaattat taaacactaa aaggagcgaa caattttatg tttgaatcaa
    21421 ttacaatgaa ttttttaaca caaccgaaag tagtagctgc ggttgatatt tttagagcat
    21481 tacaaggtgc agcaactagt ttaaaaaaca atctgatgat ttttgcggct gtagctgccg
    21541 ttgcctccat tgttcttggg gggattttct tcttctttgg ccgaagagga gctgaaaacg
    21601 ggaagatgca cgtaggttat gtattgatgg gggtaggagt tatattagct gccgcctcta
    21661 ttgtggtttc gttatttgga atgtttggac aaaccccaca gggactataa aaaataaata
    21721 gaaggagtaa aaagtacgtg gctacttttt actccttttt tatgaaagga gaatactcat
    21781 gtactttacg atttcaggca ataccaaaaa agataaagag ttaataaaaa aagcaacgaa
    21841 gaaagtggga aagcgtactg cctttttacc gaaaacaatt aaatattctg tcattgaaac
    21901 ggaagaacag ctacatgtgt taggacaagt gttagaacaa gagaatcaat cttctgttaa
    21961 attgactctc acgttacatg ataaagaagg aaaaatagaa aaggctggca cagaatacgt
    22021 ttttggccca ctggattatc aaatttcaga aggtttttat cctacattga tggatttgat
    22081 ccgccttgat gtgtttaagg aaacggatga aaccatgagt gtggaagagt cttatcgaaa
    22141 cgaaaaactg ctacaagttt tagaagaaga gttagagagc gaccaaagaa aagtgagtca
    22201 agtgagtgaa gtcgaagtaa atgatgaagt accatgggaa cgaccaatct ttccaaagaa
    22261 ggagtcaaaa gaaaaagaga cagtctatgt tgacgaacaa gctgatattc cgactcagaa
    22321 atcgatattt gaggaagaga acgatgtaat gggtcaattg gaggtagatc cctttgaaga
    22381 aacaatggag gatgaagaga cggccgaagt agaagttgat ctagttgaag ctaatgaaga
    22441 gccaacatgg actgaagggg attctcagga atatattgaa ccacttatca gtgaagaagt
    22501 agagaaaaac gaaacagaga tacaaaaggc aactgtattt gattatattt tggatcaata
    22561 tccgccagag catgaatgga tgaaagaaaa aaataaatta tttttaaatg agctttattc
    22621 gaaatatcaa ttaccccaaa cctatcaagc atttttagag agtaaagaag aattaatctc
    22681 acagggtaaa ggcacacttt tagaacagtt agagtctgtt caatcaacaa attggcatga
    22741 gcttgcacaa gaagatttat tagccacttt tgaagaacgt caacaagaaa cagatcaaga
    22801 aataaatgag tatgcgacgg aacagtcatc taattgggag agaacaaaag aggaactaaa
    22861 taaagaagaa caacgagtga ttgaagaaga agtacaaaaa attaaagagc gatacgaaaa
    22921 gaaacgcgac aatgcgtatt ccttgtgtat agagaaaatt aataacttta ctaaaactaa
    22981 tcaagaagct ttatcgaaag aaaaagaaaa cttgttaaaa gaacgtataa aagaacgaaa
    23041 agaagagttc taccgaggtt tacgtacaga taagctaaag attagcaaag aattaaatga
    23101 acaactgaat aaactttatc aaacaacgac tgaagttctt atggaaagac acgggcagat
    23161 ccagcaagaa ttacaagcac aaattccaaa atggaaaaaa gagtatgaaa ttcaacaaca
    23221 agaattgaaa gaacaagaag aaaaacaacg acaagaagaa aaagagcgcg aacaattaga
    23281 actaaaaaaa cgtgagcagc atcttgcaga acaaaaagtg gcgatagaaa aacaacggtt
    23341 agagcaagaa aaggaaaaag aagcagctgc tcgtaaggaa cgtcaagaac aaatggatac
    23401 attgcgacaa gcacagttga attatctagc acaacctcaa ccagtagctg ctgttcaaac
    23461 gccagtgaac aaccaagcaa atttaactcc ttcaccacag cgttccttta acggatggat
    23521 ggtgggatgt attgcaagtt taagcttgct tctaggtgga ggaacagtat ttgcttttaa
    23581 tcatatcaat caatcttcac aggcagattc tgtagccaca acggcgtcaa tcaaggaaga
    23641 agcccaggaa caagcaagaa aagagtatga acaacaattg gaagaattat tgaatcgtac
    23701 caatcagtca acagcagagt caagtatgga aaatagcaaa gagagtgatc ctagtaaggc
    23761 taaagaagga tcaagcgatt caactgtaca ctcaaacact tccgaaagtt cagaatcaaa
    23821 tgaggtgaaa taatgcgtat tagagaaaca acgagacgaa aagacaaacg attcaattta
    23881 gaaaagaata ggtatctttc tcatttctat cgctatactc cttcaggaga agagctacca
    23941 gaaaaacatg acaaacgtat ttctcaaaag attttttata gtggcttagc ttatcttcct
    24001 ttaaactatg ttgttacaag aataccagaa gcatttcatc gatttgagat tattccagga
    24061 agtttacaag gagtgaatat ttttcagtta caagaaatgc cgcagttatt ccattttgat
    24121 tcaactggtt tttggaatcc tttgacccca acaacaagtt taggcacacg tttagttgtt
    24181 tctacgattt gtgttgttcc agctgtactt atgggattga aaatggacat gtggtttcgt
    24241 ccgctagcag atgggcaaaa aggagataac cgattaaaaa cgttaaagga aatccaacaa
    24301 atttatccgc aaataccaga atcaaaggga agttttcctg gttatggcgg aataccaatt
    24361 actcattata aaaaatactg gtatattcag acggatacag taaatacttg tattgttggt
    24421 acttcccgct cagggaaagg ccagatagaa gttttagcaa ccattgacaa tttgtcgcgt
    24481 gcagaaagac aaagttcaat ggttgttaat gatccaaaaa cagaattata tgttgctagt
    24541 aaagatgaac tagaagctag agggtatgat gtgtatgcct ttaatatcac cgatccactg
    24601 caatcaatga gtgataatcc attggcactc attgtgaaat actggaagcg aggagacata
    24661 gacaccgcaa cacagttaac caatactttt acgaatacga tttattatga tgcaaatgct
    24721 tcagacaata aatactttaa cgaaaatgcg cagaaagctg tcaatgcgct tatttttgcg
    24781 ttattggaac aagcggatca aacaggggat tactccaaat taacaccaaa taatctcgtt
    24841 gaactacttt cagaaattgg cggttttaat tattatccag atcctgagaa tgaattcaag
    24901 cagctcaatg ccttagatga gttcatgaat cagttacccc ctggaaatat agcaaaaaaa
    24961 caatatgggg caaccaaaat tggatctgat aaagcgaaag ggaatatctt gtctacggca
    25021 attacaggat tgaatccatt taccctaacg aaaattgcga agatgacttc tcaatcgacc
    25081 attgattaca agtccattgg ttttccgaag tatttggatc tcaaattaca tgaaagccta
    25141 ttaaatcaac gcattgtcgt ggaattttat cataagggaa agaaatttca cgaggaacga
    25201 gtcaaagttg gctatcgtgg tttttgtgaa atcaactttg attgtcattt agagcaggga
    25261 gatcatgttt gcttaaaata caatcatcaa ggaaaacaat atgttgcttg gtatgagttt
    25321 tctcaaaaag tattgaaaga cgaagaggga aaaatcgttt atcgaaaaaa acgaggagaa
    25381 actcatttgc cagaactaga aaaagaagcc gttctaacat tagatgagaa gaaaagtaac
    25441 ctattagtag agtctattcg gatgcactat accgataaac caatggctat ttttatgtta
    25501 acgcctgatt atgatccatc taaccatatc attgttagca tctttcttag tcagttgtat
    25561 aaagaattat ctacgcaatg tgttaagact aaaggagata aatgtcaccg taggattcat
    25621 tttattttag atgaatttgg aaatatgcca ccgatggaca acatggaagg aatcatgacg
    25681 gttacggcag gtcgtaatat gttatgggat ctgtttattc aatcttatca gcaactttat
    25741 gcgaagtatg gagaacaaaa cgcagcgatt atcaaagaaa attgtcagac acatatttat
    25801 attatgtcga cagatgataa taccatcgaa gaattttcta aaaaagtggg gaataagacg
    25861 gttgaacaag agaacagtac catcaattca ttaggtatga atactcatat caatcgcaat
    25921 gttgattcag atcgtatctt aactcctgaa agaatttcta cttttttaga aggtgaaacg
    25981 attgtactcg ctcctttaaa acgacaagat ttgaaaggtc ataaaatacg gccgtatcct
    26041 atttttaatc atggggaaac gaatcttcct tatgcttatc aatatattga agatttcaat
    26101 ccatcgtggg atatcaatga tatagacata cattgtacac atgcggactt ggatcttaag
    26161 gctttacaaa ttgattatga ttatttccta ccagatgaat atgctagaaa tctctatcat
    26221 ggactgcatg atcaattaga agaaaaaaac gaagaaaata tgttttataa aatcgttcaa
    26281 tcttttgaga atgagacggc taaaaaattg ttaattcaat tttacgaaga acaagcaacg
    26341 gatcgtcttc aagaatatgt tgaaaagttg atcaaaaatg aagaaatttc tgaaatgatt
    26401 aggaaacggc tgttattgga agctgaaaag gcggtgaaag aatgatcatt ggaggaattt
    26461 tctctggcat agccgactgg tggtcaggtt tattcggaga aggggatgca gatcccaaaa
    26521 ccgtaacgaa agtcttacaa gattatggta attatctgca gtatcaagat gtattcagtt
    26581 ggatttgtaa tactttttta tggggattga tcaaagggtt atataatctc aatactttat
    26641 tagaaaaaac aatttatcaa agctttgatt taaaagactt attgaacgcc gctggtgtta
    26701 atgaactatt tcaaagtttg attagtaagg tattggctct tttttgtgtc gtcacattaa
    26761 tttatttagg cttgaaattt tttatgagta aacacccacc gaaagtcaaa aatatcttgg
    26821 ttaatttatt tatggccatg atcttgattt ttggtggtag ttctttaatc gatgaagggt
    26881 taaatatcag taaaaacttt tatggagacg tcactgcagc aaataaagca gataaaacgg
    26941 gttcacctgc ttttcaaatt attcaaaata atgtgattga tgtcagtaca ttactagcga
    27001 ctgacccgaa taaagtagaa tccttaccaa cagataaaag aaatgcttta acagcgaaaa
    27061 atttcaaaac agcgaatatc aatgggatta ttacacctga tcaagctaag aaaatgtctg
    27121 aatcaagtga tattagtaca gtacaaaaag atcggttaaa ggcattacag tatcgactag
    27181 agttagacga taatgggaaa gaaatccctg ttcaaattag tgatgaaggt ttagcaaaat
    27241 atgtgtatac gtcaggctat cgtcgataca ttagtagtcc agggattatt ttggctgggg
    27301 aatcttcttt gtcggtagcc tatttattta ttttgtttac aatcgttact tgcattattg
    27361 agctagtatt taaaaaattc tatttagtaa ttgccgcgtc aacggacttt gagacaggac
    27421 aacggatgaa aagtgcgata gaagatattt ctcaatcctt cttgttattg gcgtttacga
    27481 ttttagaatt acgaatctat acattaatgc tttcaggtat cggtgatttg catgcggtag
    27541 gaaagatcaa tggattcttg tatgttgttg ctttaattgt gctaactatt gcgctattca
    27601 aaggctctca atcggttacg aagattttcg gtgttgatac gagtctgaaa aacggcagca
    27661 attctcttct tagcatgttt gccttaggaa atattgcgaa aaatgtgggt agcggagcta
    27721 aaaaccttgc aagtgctggt aagagtggtt taagccattt aaatgatatt cgtaagaatg
    27781 gatttggcca tcgaaaagat attacccatg ataacgggga agaacaatca gacgataaag
    27841 ctacaactgt acctaatagt aagaagacag tttccgaaat gttcgggaaa gcgaaaaatg
    27901 gtgtttctaa agccgcagaa ggtcttggtt acgtcaatga acgtgggtta aaaggaacag
    27961 ttgaagatct tacagaaaaa gccaaagaca ccttagaaga gaaattagac ggcacgagag
    28021 ctaaagaatt tgctgaagct gtgaagaatc catccgaagc actagaaaaa caaaaagaaa
    28081 aagcttcagc agtcaaagaa ggactaaaag atgcgtatgg tgaaggacaa gtcaatgcag
    28141 cagtgaaggc aaatacaaca agtgaaaaag aaaatcaaga aggtgcagcg attccttcag
    28201 ccaaagatca ccaagatgag ttacattcta acgaaaattc gatcggagaa aaagattcag
    28261 aagaaggaca acatggtcag ttaccaaaaa ccgatccaga acaatatcgt tataaatcta
    28321 acattaattc tgaaaacgaa aaacgcattt cagatttacc aaaacgaaat caagaagtac
    28381 aaacggatga ggattccatc gatctgccaa atgataatgg catcgaagtt ggaactgaaa
    28441 aatcaacgaa aattggtttg cctaagacac aaaatttacc aatgaaagat agtcgtttga
    28501 atcaattcaa agagaatgat caaagctttg ttcatcaatc acctgcaggt actgttcaaa
    28561 tgaaatcaag tcgtttgcct gaaaatggaa atctgacaac tgtttcttac aatttagctg
    28621 aaagtggtga aacagagaat gcgtccgttc aaaatattgt gacaaaagaa gctgcaccta
    28681 agccaatcaa taaagttcat aatggataca gaccagcaaa cgtagcattt actgcaccga
    28741 caaaaataaa tgtgacaaga gaaactaaaa acaggaacaa tgaattgaaa gaacaactat
    28801 tgaaggatat caaaccataa aaggcctatt taagggcctt tttctttata aaacaagttt
    28861 aaaatggaaa ggagaaaatt gtggaggata ttttaatagc tacgtttata actgcactgg
    28921 gagcattttt aacgatattt gtggtgacta ttaaaggatt taaagatacg gatagtttac
    28981 aaaaagatca tcagtctatt ttagatggtc aaaaaacaca taccgaaagc attattgtac
    29041 acctttcaga aggattcact tatttgaaag atgctatgcc cacattcaca gtaaaattaa
    29101 cggaaatatt tcattctgtt gagcaaatat cgtcagaatt gaaagagcaa agacaacaaa
    29161 aagatcgtca acttggctca cttaatttta ggcaagaaac gatacaagaa tcattggaga
    29221 atgtaaatcg attaaacgat gaaatgcaac gagttcattt ggaaaatgaa gaattacgcg
    29281 cacaaaatta tgatttaatt caaaagaaaa gaaatctgga acaaaaaatt gttgaattaa
    29341 aagaagaaaa tcgtcaattg aattatcaat tacgacgagg aaaaaatcgt tctcgtgatt
    29401 taggaaatga attagagttg taatatttag aaaaacgctg tgagaaatca cagtgttttt
    29461 tatttctaaa aatacaaaat ataaggggta tggttatatt atggataaat acattcatat
    29521 gaaaaatcct ccaagattta gtggggaatg gaagtttttc gcctttttct ttttagatct
    29581 attaacgctt ggtggctgct ttttttgggc gaaaatagtc aataatcttg tccacttacc
    29641 actctttttt gcactcttga attatggatt atggcttgcg atagcgttag tgattgtttg
    29701 gcgaccctat aataaccctg gtcaacgcca aatttttgcg attatcgaat ctattttctt
    29761 tacggataag aaccactatc atgcgttaga tcctaaccga aattatcatg gtacgtataa
    29821 ggaggatgaa taaatgcgag tcaaaggaca aaattcagtt gataagaaat ccattttgca
    29881 gtttggaaaa ccagaagagc gctctatctt ggacttattt ccatataaat cctgtacaga
    29941 agagggagtc ttaattacta gagaagatca ttttcagcgt tattatcgtg tcgtttccac
    30001 tgacgtggag ggattaaatg aacaagagaa actagaacga atgaatcagt tgaccaccgt
    30061 catgcgtacg tatgtgccaa caattaagtt agttagtttg accacagaga cggatctaac
    30121 ggaacaaatc gtgcaaaagc ggcagttatt agataaaaat cgtatggaac agtcactagg
    30181 aagaaatcta cagcgattaa gaaaatatga aaagaaatta gtagaggaga tccaggaatt
    30241 aaaacgggca gaacaagaac gtcctgactt aagcttcttt ttcgttattg aaggaaagac
    30301 aatcaaggat ttacaaacta gaaatcgtca gttaatgcga tctagtggca ttttagggtt
    30361 aaaaccactc tacaaaaaag aattgattaa gattctttat cgaatgaaca acatgaatga
    30421 cgaataaaaa agatggagga aatgattcat gctagatgtg ataaaaacag ctttttcaac
    30481 gcaaagtaat caaaaggtga ttgatccatt aaaacaactt ggtaatcgtg aaatagagat
    30541 tttaaaatca aaaggttatg atttagattt cttaaaacaa gtgatgccac aaggtgggtt
    30601 gaattttgat gaagaatatg tgacctatgg aaatggttat tcacgatgtg tgacagttta
    30661 tcattacaca aaaaatccta ctcttttttg gttggccaat ctcatgaaca atcctcatac
    30721 agtggccaca ctagatgtta gcacagatga aaagcaaaaa gtgattgatc aaatcaaccg
    30781 cgcattagat gaattaaatg atcgatcaga taatgaacga aaagcgactg accgaaataa
    30841 aagtgcggaa gaatacctgg aactagcgga atatgcccga aaattgactt ctaatgggga
    30901 aatttctaaa caagtcaaag tgagagtaca tgtttacgga aatacgatcc aagaagtgga
    30961 tgaacgggcg caggaactga tcgaaaatct aaaagggatg gattatcgtg cggtgactta
    31021 tctgcataaa accaaacgag attggcaatc gatgtttacc atgttcgatg aacaagctga
    31081 atggtttgga aatatcaaag ggcaatcact tccatcgtta aacattggcg gaggattccc
    31141 gttccaccac caaacgctaa aagatccagg aggcacacaa tatggggaaa ccatgacagg
    31201 cggcccattt gtctggaatg ccacgtataa aaatagtgta cgtttatcta ccaatacctt
    31261 gcttctagga atgatgggag ctggtaaatc gaccgttctt aaaatgatcg cggaagccca
    31321 tttagctgca ggagacttta tttggggctt tgaaaaggga aaagacttta ttcctttctt
    31381 aaaggaatat aacggtatta tggtgcgttt agacggatct gacgggatga tcaatccttt
    31441 agagatcttt gccacacgga cgtatgatga agcatccagt ttatatgacg atggttcagt
    31501 caaagatttg aagatcaatg aagcagcgtc ctatcaaacg cacttagaca aagtagtcta
    31561 tcaggtacag ttagtgagtc ctcagctaaa aggaacgatg aaagcagaat tcaagaccta
    31621 cttgaatcgt ttttatgaag agtatggaac agtaccacgc ggttttactt cctcaaattc
    31681 gcgttcaaat actgatacgc aagtcacagg gaaagatcca gaagcttatc cgacgttcaa
    31741 agaattttta gcctttttag gacaactgga actaccaggg gcttcccaag agaaaaagaa
    31801 tcggaaagaa gaaatggagt ctatcgtgga atccttatgt gagacttatg gcatgatttt
    31861 tgatggtcat agtacgattc gacaccttga ccaacaacag ttggtctttt ttgacattga
    31921 ctctattaca ggcctagatc gaggggtaca acaatgtcag atgtacatgg ccatgacgtt
    31981 gatttggaat caggcattga ttcaaggacg aagacaacga cgcttaatta aagaaaaaca
    32041 aatggaagaa caagacttca aacgcttctt ggcgatgatt gatgagtgcc ataatgcgat
    32101 taatccagat ttcattgaaa cggtaaatta tgtcacaaac ttccaacgag aaatgcgtaa
    32161 agtagaagca atgactgttt tagctacaca atccccacaa gaaatggtgc cagaaaatat
    32221 gtcttctgat aacttctcga aactgaagaa agtctttgaa ttttcttcta cgaagatctt
    32281 tatgcgtatg gatgaatcta ttttacgtca tatagaagga ttagttggta aatcaatgac
    32341 gaactcagaa ttagaatcca ttcctcaaca aaatcaagga gacgctgtga tcaattttgg
    32401 ctcaaaagaa accattcgtg ttcattttag tccgaacaaa cgtcaattaa aattgtttga
    32461 tggaggaaaa taatggaaaa ccaaaatgaa agtttaatca aacagtatgt taagcgtcgt
    32521 gcaaagcggc gcttattttt gtgggtgttt ggtacttctg caggtttgat tactatattg
    32581 atcactgtgt ttgtgaccct ttttctaata cttgcggcag gttctattga taattctgat
    32641 tcaagtagtg gtggcgaagc ttttacagga gaatattcgg aaggcttacc catttataaa
    32701 gaaatcaaag gaagaggccc tttttctgat gagattgcgc aatatgctgt aggtgcagca
    32761 gtgaagtata aattattacc aagtgtgatc ctttcgcaat acggttatga atcagcgttt
    32821 ggtacgtcgg cgtccgcaag aaatgatctc aattattttg ggattacgtg gtttgatggg
    32881 tgtctgtttc ctaaaggaac tgcgcgtgga attggtggca ttgaaggtgg ctggtacatg
    32941 aagtttccca actcaaaagc tgccttctcc tattacggct ttatggtagc cacacaatca
    33001 aattttaatg cttgtgtcgg aaataaaagc cctggcgcaa gcttattgat cttaggacga
    33061 ggagggtatg ccgccgcagg aattactgaa gacagtgcct attataaaaa ttgtatgtct
    33121 attattaata caaataaatt gatggagtac gatgagtttg cgattaaaca ctggagagaa
    33181 ggcggcggaa ctggtggtac gattacagga agctggggca atccattccc aggaagtagc
    33241 ttagataaaa attcgttcag tggaggacaa ctttttggga aaaatccagg aggagaattc
    33301 cgacctaacg ggttccatga tggactagac tttggttcag tcgatcatcc aggaagtgag
    33361 attcatgcgg ttcatggcgg aaaagtcgtg tacgttggca atcctggtat ttcaggtttg
    33421 ggtgcgtgtg tgatcgtgat taattacgat ggcttgaata tggtgtatca agaatttgca
    33481 aatagtacag gaaattctcg agtgaaagta ggcgatcaag tgaaagttgg tcaagtaatt
    33541 gggatacgag atacagcaca cttgcattta ggatttactc gaatggattg gcgtcaagca
    33601 caaggacatg cattcattga tgatggtaca tggatcgatc cgttaccatt tttgaatagc
    33661 agcaaaaaat agatcaggag aaaaaatatg gaaaataaaa ccttaaaaat cgtcttaaca
    33721 gctgcaatta gcgttagttt aatcggcaat attgcgttgt tttggcagct taaagaagaa
    33781 caagagacaa atacctataa aattgaagaa gtggctaaaa acgcgtctga taagctcaaa
    33841 aaaaattctt ctgaagcaca ggcgaagatt gacaagttaa atcaaaccat caatgagaaa
    33901 aaccaagaaa tcgatcagct gaagcaacaa gatggcacaa aagcaaaaga ggaagtaact
    33961 gaagcacaaa gaaagacggc agaagagttc ggtcaattgg ccattgataa atcattaagc
    34021 agaaatgaat taacggaaaa actaaaagat gtcgcaaccc aagaagtgat cgacaaatta
    34081 agtcctgtag acgatgatca ccaacatgat gattacggaa gttactcttt tacattaggt
    34141 gacgtgcaaa cttacgctca aacaagcagt gtaaaagagg aacaaaattt tgtcgtattt
    34201 gttgattata caatcggcaa tcctcaattc aaagatgtca aaccacaaaa aataaaaggt
    34261 ggattaactg tcactgaaaa acaagtagat ggtcaatgga aagtcacaga ctttagttat
    34321 ttcactcgtt aggaggaaga aaatgagtaa gaaaaaagga gcaagacaac gttttaaaaa
    34381 acgaaaaagt tatcttagat ggctggggat ctttatgatt ctcggctttt tgattcttgc
    34441 tagtccgatt tacacacata aaaaggtaga cataccagat gaagtaagca cgaacgcatt
    34501 tttaaacacg aaggaactga cgatggtttc aaaagaaaaa ggagcgaacc agcaattagt
    34561 ttttgaattt gcgatcgacg atgaagatca gagcttatta aaagaactag ctaatcttaa
    34621 ttatcgtgta gaagtaaaga cagctaaagg ggattatcaa gcaataaaag ccaaagtgat
    34681 caaggtgtct gatgattatt ttgtagtgaa gttagcacat gtaccagaag aatatattgc
    34741 tatgcgatta actattattc ctgaaaaaat tgatccaaag gtggatatgc aagaaccgca
    34801 agatctgatt ttttatattc acgaagataa ggtcaaagat cacgtgaaag acgaagatta
    34861 tgaacaacat gcgatcaatt acaaagtgaa aggatacaag aaagaacaaa aagcagcaca
    34921 aaaacaaatt gaatccttcc aagcaaccat tgatttgaat gaagaattag tgaagaaact
    34981 aaaagatcaa ttgccttatc aagtcgcaga agatcaggaa aatactgaaa ataagattaa
    35041 tagttaccag caagaaattg aaacatcgaa aacgcaaatg aaagatcaag aagagagcat
    35101 tcaaaaactt caagaaaaaa ttgatcgtat gacaaaagaa aatatttaga agaataggtg
    35161 gagtaaaaga aatgaagcga gcgaacttgg tcggcaaaga tactttcgct gagcagaaag
    35221 tattgattaa agcctatctc aaagttgtaa aagctaaaga aatatgtcaa gaagtgaatt
    35281 atctaacaca acaatatctg agttgaagaa tggtagaaag agtttagata ccttaaaatt
    35341 cagatcattt gaagctctat atatagctgc taaaaaatat tttacagctg ataataaata
    35401 aaaaattaag gtgggttcta tgtgaaaaaa acgtatcaaa agtttttatg gattagctat
    35461 atcgtcctat ttatcgttgg gtttctcgtc agtgtgtccg tgatcgtcgg aacgcttttt
    35521 cttttgttct ctgacgaaga tctggtactt aaggggttaa tgagtacgtt atcgtgtgtc
    35581 atgttacttt atttatgtat acagatcaac gaaattatgc cccctcattg gcaagaaaag
    35641 aagaaagaat ttaaggaaga aatcgaaata aaatccaatg actggattga atacacatgg
    35701 cttcctctga aaagaaatag caaacgaaag gaattttggg cattgcaatt atggccaata
    35761 ggaaaacttt ttatttatat ggcttcactt atggttactt taatcggtta tttggtggtg
    35821 gtctatgggg tggcctatta cttgttaagt gagccaaaac agatcgcggc gtcaaatatt
    35881 ttcacggcag taatgacatt aatgtgtgtc atgtgctttt ctatttttag ttacttactc
    35941 gtccaattta tcaggcaaaa tttaacaatg agtaaacttt tcaaaagttt attggactta
    36001 cttatcttag gcagtatgtt aacgactcta acagatcggt tcgaacaatc tgaaaaaacg
    36061 gtagagggga taaagaactt cttaacgacg attgatcaat ttataaatgg atatatgtat
    36121 ttgtttgaag taggctttat tctcactttg tttggttgtg tatttataaa actcattaaa
    36181 agatcaatcg aaaaagaaat ggttattgat ctaattccga cgctgagcgg ctatgagtat
    36241 tacgttgatt ttggaaagta tgaggagttg atccatacgg atatcgttca cacgagtatc
    36301 catgaagtaa ccgttaaggg catcagatct actttaaaag atggacagga gacgaaaaca
    36361 atcgaccgaa gaaaagaggt ctacaatttt tataaagttg aagcaagtct acgatatggc
    36421 attgggaaat tgaggttaga tgggagtaat attcaacaaa acaaaccata tgttttagga
    36481 aaagtggtga tttagaactt cctatgaaag atgaataaat aaggagaatc ttttgaaaat
    36541 gattcttctt tacagaattg tgcttatagt tggcacggag ttaaaaatct taaagaagga
    36601 gcagttattc aaagtgaaag aacatcataa tcagttacta tgtattaaaa cgggtacgat
    36661 gaacattcaa taccgaacag aatatttaga attaacgaat caaactgatt ttttgtcgat
    36721 tcgagagcaa cataagcaag aaaaattaat ggctacttat agccaattga ttgatgagtg
    36781 ggaacaattc aaggaatcta aaacataaaa ttccatttaa acaccttatt ttttaaagag
    36841 cataaggaaa cgtgtaccca ctttcaaaat aaagtgggta gataggctgt gcctatcacg
    36901 tttctgaaaa aaataaatga ccccaaaatt ttcaatttat gtgtaggttt atgggtagca
    36961 aaaatatgaa tgtgggcagc aaaaagttca tttgtgggta gtaaaattca aatgtgtgta
    37021 gcaatgtgtg tagctacaca cattgctaca cacgctataa catatagtga aaaggagata
    37081 tttatggaag taaaaataag agatattgat gaaaaaacga ttcaaagaat tgaccgaaga
    37141 tgtattgaat taagtgaacg caccgggact aaatggagcc gaaatcgata cctaaaagtt
    37201 ttgattgaaa atgattttga ccatgaactt atggatcata gaaaagatca atttgatcgg
    37261 ttgttagaaa aatttgtgga tattcaaact tataatacga aaattttaga agaatatatt
    37321 gcaacaaata atcaattaat cgccttgtta attgaataat aaaaatagta ttgtgaattt
    37381 ataaaaggag gaaatcaatt ttggcaaaag caacaagaaa acatgtatat ctttacgata
    37441 tgcatatcga agtacttgat gaaataattt ctactcatga agatatatct aattatagtg
    37501 aagcagtcag acatttgtgt atgatgtatg atccaaaaat cgaagaaaaa ataaatccaa
    37561 ttcaaattaa attgaatgca atgggaaaag aaatttctat attaaccgaa atggtttcag
    37621 agtttgcgga tcttcatttg aaagatacag gaatactaat tggtacaaat tcaactgtct
    37681 atcaagaagc aaaagagcgt gtggaaggga aaataaaagc gaatcaaacg aaaaagtatt
    37741 ctcctaagat caagaaacca ataaatgaat ctgttcatgc cagagtagac ccgtttgatc
    37801 caacaaagtt tttaaaaaga taaaaagtag aaggggaaca tgatgaataa atcgcctgca
    37861 gtcattctca cttgtcaatt taccttgccc aataaaaaat ctttttcaac atacattgat
    37921 tatatgacaa gagaaaaagc gctggaagaa aaggaacgac gcacgccgga cgaagaacag
    37981 gaactgcaac gaatcaagaa tgctttagag gatttttata ttcctgaagg agaaactttt
    38041 tcggagagta agacagataa agaattcagt gaaacgtcga atgaagctca atcgttgatg
    38101 gaacatggaa tcaattttga caagttagag gaacaagatt ttaccaaata tctttcttat
    38161 atgacccgtc actatgcgtt agaacaaaag aaagaactga cgcaaaggga acaaaaagaa
    38221 taccaacggt tgaaccaagc aatgaaaaaa tatcaaacag agccacataa aaaagcttca
    38281 ggaaatcttc ctggagtttt ttctatggct tcagacgaag tgaaaggaag tgatctgaag
    38341 gagatcaaac aaatcttcca aagagggcaa caaaaaggct caatcattta tcaagatgtt
    38401 gtctctcacg acaattcgta tcttgaaaaa atgggcttgt acgatcccaa aacagatacc
    38461 ttagatgaag aaggattaaa agcagctgga agaaaaatga tggagacatt attcgagaaa
    38521 gaacaattga atgaaacagg ttactggatg gcaacgattc accgtaacac taagcatatc
    38581 catattcatt ttgcagttgt tgaaaaagaa aatacgcgta aaccttacac ggaggttgaa
    38641 aatggtgtga gttatatcgt accgaaaggt aagagaagac aagcaacatt agacgcaatg
    38701 aagaccaatt atgtacatga gttagaacgt ttttcttatg aaaaggatcg aatgattggt
    38761 atggagaaac gaaatttatt gacgcggaaa agtgatttgc gtaacacctt aacaaaagtg
    38821 gtaaaagagc cagcgcgtta cgatcgacac gcaatgaact tattaaatga agtatataaa
    38881 accctacctg acaaacgttc ggaatggcat tatggggatg aaaaacgaac caaactttca
    38941 ccatacacaa gagagaaact cgatgagtta accaaatatg tgttaacaaa agaacctgaa
    39001 tatcaagaat atatacagat ttcaaaatca ttgaaagaag aagcaaaaag tctttatggg
    39061 gaaagcaaga gagaatcaaa ggatgcagaa aaaaatgctc tctttgattt gaagaagcgc
    39121 acaggaaatg ccattctaac agaactgaag aaacaggata gtcaaataaa acctttaata
    39181 gaaagtatgg atcagatgca atctatttac aatgaacgat cctttcgaac gcttaaacag
    39241 ttaccaacga atgaatacaa atatagttac gaagaattca tgaagcgcag gaaacaattc
    39301 caacaaagag ttgtcacgca acggagtttg cgtcaattaa atcgaacgat taatgcccat
    39361 gaagaaaaat accacgcaag taaagcctac gaagagcaac aacgaagaat tcaaatggaa
    39421 caagaaagac agtaaagaca gtaggaggaa tagcaatgaa acaatattta gatcaatgga
    39481 aagttataga aggatcatta agagaagaac gaatcgaaca acttcccgat tgtttagaaa
    39541 aagagcattt gtttcagata agagaaatgt tgagaaacga acagtttgat ccaaatcaat
    39601 ttttagtcgt tgagtactca gctactggtg tgtactgttg taatcatgtg aagggtgaaa
    39661 aatattttat cattcaagaa tatgagggca agttagcgcc ttattatact acttgggaaa
    39721 tgaatgaaga ggggatcaat aacttcccgt gtaaaagcat tgaagagtct atttcactca
    39781 cagaatgtta gttgttaagt gaataaaaga agtaaaagag tcctgaacgt aattgtccag
    39841 gactcttttt ttcaatgaat tgttttccgc caattcaatg agtggtgcga tttgcgacta
    39901 cattatatca aaagaaagag aagggaggaa gaagaaatgg cttattcaac gattggagtt
    39961 gttgttgaaa aaagcagaga caatctcgtt tttgtgacag aaattcaaac gggcagagct
    40021 tttgtcgtca cagacaaagc ggcaaaagcg tatcaaagtg gcgatatttt aacgttaaat
    40081 ctgactacga agacgttcgt cgatgcggca gaagattatc c
//
LOCUS       DAFEEZ010000018        39890 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000018
VERSION     DAFEEZ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.018"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(28..726)
                     /locus_tag="LP245_001059"
     CDS             complement(28..726)
                     /locus_tag="LP245_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBL1518991.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(719..2071)
                     /locus_tag="LP245_001060"
     CDS             complement(719..2071)
                     /locus_tag="LP245_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBL1518992.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2294..3694)
                     /locus_tag="LP245_001061"
     CDS             complement(2294..3694)
                     /locus_tag="LP245_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBL1518993.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3855..4592
                     /locus_tag="LP245_001062"
     CDS             3855..4592
                     /locus_tag="LP245_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBL1518994.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4717..5196
                     /locus_tag="LP245_001063"
     CDS             4717..5196
                     /locus_tag="LP245_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBL1518995.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5193..5960
                     /locus_tag="LP245_001064"
     CDS             5193..5960
                     /locus_tag="LP245_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1518996.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6190..6759
                     /gene="lepB"
                     /locus_tag="LP245_001065"
     CDS             6190..6759
                     /gene="lepB"
                     /locus_tag="LP245_001065"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL1518997.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6863..7465)
                     /locus_tag="LP245_001066"
     CDS             complement(6863..7465)
                     /locus_tag="LP245_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL1518998.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7571..8040
                     /locus_tag="LP245_001067"
                     /pseudo
     CDS             7571..8040
                     /locus_tag="LP245_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8146..8730
                     /locus_tag="LP245_001068"
     CDS             8146..8730
                     /locus_tag="LP245_001068"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBL1518999.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8733..9806
                     /gene="prfA"
                     /locus_tag="LP245_001069"
     CDS             8733..9806
                     /gene="prfA"
                     /locus_tag="LP245_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBL1519000.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9799..10638
                     /gene="prmC"
                     /locus_tag="LP245_001070"
     CDS             9799..10638
                     /gene="prmC"
                     /locus_tag="LP245_001070"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBL1519001.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10631..10810
                     /locus_tag="LP245_001071"
     CDS             10631..10810
                     /locus_tag="LP245_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519002.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10832..11857
                     /locus_tag="LP245_001072"
     CDS             10832..11857
                     /locus_tag="LP245_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBL1519003.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12032..13276
                     /locus_tag="LP245_001073"
     CDS             12032..13276
                     /locus_tag="LP245_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBL1519004.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13429..14376
                     /locus_tag="LP245_001074"
     CDS             13429..14376
                     /locus_tag="LP245_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1519005.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14510..15139
                     /gene="upp"
                     /locus_tag="LP245_001075"
     CDS             14510..15139
                     /gene="upp"
                     /locus_tag="LP245_001075"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBL1519006.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15278..15520)
                     /locus_tag="LP245_001076"
     CDS             complement(15278..15520)
                     /locus_tag="LP245_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519007.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15641..15713
                     /locus_tag="LP245_001077"
     tRNA            15641..15713
                     /locus_tag="LP245_001077"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15674..15676,aa:Thr,seq:cgt)
     gene            complement(15832..16470)
                     /locus_tag="LP245_001078"
     CDS             complement(15832..16470)
                     /locus_tag="LP245_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL1519008.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16593..17225)
                     /locus_tag="LP245_001079"
     CDS             complement(16593..17225)
                     /locus_tag="LP245_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBL1519009.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17576..17875
                     /locus_tag="LP245_001080"
     CDS             17576..17875
                     /locus_tag="LP245_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL1519010.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            18370..20535
                     /gene="acm"
                     /locus_tag="LP245_001081"
     CDS             18370..20535
                     /gene="acm"
                     /locus_tag="LP245_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBL1519011.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(20807..21292)
                     /locus_tag="LP245_001082"
     CDS             complement(20807..21292)
                     /locus_tag="LP245_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBL1519012.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    21382..21727
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            21772..22413
                     /locus_tag="LP245_001083"
     CDS             21772..22413
                     /locus_tag="LP245_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL1519013.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            22432..23067
                     /locus_tag="LP245_001084"
     CDS             22432..23067
                     /locus_tag="LP245_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL1519014.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            23085..23900
                     /locus_tag="LP245_001085"
     CDS             23085..23900
                     /locus_tag="LP245_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1519015.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            24219..25655
                     /locus_tag="LP245_001086"
     CDS             24219..25655
                     /locus_tag="LP245_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1519016.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            25844..28291
                     /locus_tag="LP245_001087"
     CDS             25844..28291
                     /locus_tag="LP245_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBL1519017.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            28521..29588
                     /gene="rlmN"
                     /locus_tag="LP245_001088"
     CDS             28521..29588
                     /gene="rlmN"
                     /locus_tag="LP245_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL1519018.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(29781..30884)
                     /locus_tag="LP245_001089"
     CDS             complement(29781..30884)
                     /locus_tag="LP245_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL1519019.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            31437..31985
                     /gene="aac(6')"
                     /locus_tag="LP245_001090"
     CDS             31437..31985
                     /gene="aac(6')"
                     /locus_tag="LP245_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBL1519020.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            32531..34192
                     /locus_tag="LP245_001091"
     CDS             32531..34192
                     /locus_tag="LP245_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1519021.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(34262..34609)
                     /locus_tag="LP245_001092"
     CDS             complement(34262..34609)
                     /locus_tag="LP245_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBL1519022.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            34693..35634
                     /locus_tag="LP245_001093"
     CDS             34693..35634
                     /locus_tag="LP245_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1519023.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            35635..36678
                     /locus_tag="LP245_001094"
     CDS             35635..36678
                     /locus_tag="LP245_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1519024.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            36684..37754
                     /locus_tag="LP245_001095"
     CDS             36684..37754
                     /locus_tag="LP245_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519025.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            37744..38697
                     /locus_tag="LP245_001096"
     CDS             37744..38697
                     /locus_tag="LP245_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1519026.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            38709..39719
                     /locus_tag="LP245_001097"
     CDS             38709..39719
                     /locus_tag="LP245_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1519027.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
BASE COUNT        13605 a         6869 c         8129 g        11287 t
ORIGIN      
        1 tttgtcacat tccccttttt cgaataacta ggctgtttgt ccttcaagat agggcagatc
       61 caattcttta ccgtaacgtt gttctaaagc taggcggatc aaacgagctg ccaggttctc
      121 atttcttgca aggataggtc catggaaata agaaccgaag acatttcggt aaatgacacc
      181 ttcagattgg tcttcaccat tatttccttg accttgtacc actttcccca aaggtcgttc
      241 accttcacct aagaaagtcc gaccattgtg gttttcaaat ccataataag tttcattgaa
      301 ttcttcgtta tggataacga tatcaccgat aaaccggtta ttttcctgac ttaacgtgta
      361 gtgatccagt gcactgattc cttggatctt ttctccatta gctcccatgt agtagtgacc
      421 tagcaattgg tagccaccac aaatggctaa catgacgcca tcattttcga tatagttgat
      481 caaagaatct ttctttttct ggatgtcttt tgaaatgatt aattgctcaa agtcttgacc
      541 accgccaaag aaaaccaagt catatttatc agcatcaaaa ggttcatgta tactaacgat
      601 ctccgtatgg caagaaaccc ccattttttc tgctatatat ttcaacatca aaaggtttcc
      661 gttatcacca tatgtgttca tcaaatttcc ataaaggtgg gcgatattga gttcataatt
      721 agccacggtt cattcctcct ttgataaatc cttgagcagc tagttcttta cgaagctgca
      781 atacagcagt gtaagtagct aaaatataga catgctcagt tggcaattct ttgatttttt
      841 cgattacttc tggtaattct tttgtttctg tcaatttatt ttctggaatc ccggcaactt
      901 ttagacgtaa agtcatatct gtatgacggt ctcctccaga aataacagct gggatatcca
      961 tatcggcaaa gttttcaaaa ttaccatccc aaatccagct gacatcgatt ccgtctgcgt
     1021 aattggcatt taataaagcc actaaagaaa atggataagg agctagacca atcatatcga
     1081 ttacttgatt gatacctaca ggatttttga caagtactaa tgtacatttt ttcccattga
     1141 tattgatgac ttcttgtcgg ccgaatactt tctcgtcata tcctaaacct tgtttgattt
     1201 tatcaggatc gacattgaag tactctgcca ctgcagtagc tgctaaagca ttgtagacat
     1261 tatacatacc gccaacttcg attccgtatt catgaccatc gatcacgaaa tctgctgaca
     1321 cattgtccat ccgtaccata tcagttaatc gataatccaa ttcaggacgt ttgaagtcac
     1381 aatttggaca gtaatatttc cctaagtttg cataagtgat cattttataa tgcaagatgt
     1441 gatgacaatt tggacataag acaccgtctg tattgtaatg agccatttgt tcacgatctt
     1501 cttcatggtc aaagccataa tattttctag gattgactgt ttcgatagaa ttgaagattg
     1561 gtgaatcacc gttactgata atcgttgcat ttggtgactt tgcggcaccg tctacaatca
     1621 ttttataggt cgtatagatt tctccatacc gatccatttg atcacggaaa atatttgtaa
     1681 ataagaacag ttctggtttc atatattctg tgactttgct caaacttgct tcatctattt
     1741 ctaggacagc aaactttttc tgtccttttt ttggttttgc ctgcaagaaa gtcgatacaa
     1801 ttccctgtac catattcgca ccagtagggt tggttagaac ttcatcgaat tgctggcgca
     1861 aaatattgac tgttaaagcg gtagtcaatg ttttaccgtt tgttccggtg acaacgacga
     1921 cttggtagtc ttttgccaaa ctatctagta tatgtggatc gactttcagc gctagtttac
     1981 ctggtaaact tgatccgcct ttaaaaaaag tttttaatgc ccattgcgac gtttttccaa
     2041 ctgcaatcgc aaaatgactg cgtattccca ttatgtaacc tccaaaaacg atttgctgac
     2101 gaataaattc aactaatcat accatatgtt gaaaaaaagg ttaaattgct tttcttattc
     2161 ttaagaaaag gttacggctg aaagtgcatg aaatcggaca aaatcgcatg atttaacaaa
     2221 aaaacagctt gaaacaaaat gattgtttca agctgctgtg attttattat tccctcttac
     2281 ctatattccc attttaaccg ataataattt tctcgcttgg atattcatag cctagatctc
     2341 gtgtttcttt tggcacgaat aacatcaatg tatatagcat tccgatccgc ccaataaaca
     2401 tcagtgtagc aatcgtgatt ttgcccacaa cagacaagtc tccggtaatc cctaaagata
     2461 aaccagttgt tccaaacgca gaagttactt cgatgatgat cgagatcagc gtttgttctt
     2521 ctgtagcaga taaaaaaacg atacaaaaga aacacatacc aagagaaagc ataaagacaa
     2581 cgactgattt tcgcacatca tcttgatcga ttctccgtcc aaaaatattg atgttatctt
     2641 cacttttgag gaaggaatat agatacaaac cgatgattgc tacagtagtt gttcgaatcc
     2701 cgccgcctac agaactagga ctgcatccga taaacatcag taaagaaaaa atgatcagtg
     2761 ttgtgatttg aaaatcaccc aaatcgtgaa tctgcagacc agcattacga gtcgtaatcg
     2821 aataaaacat cgaattgatc catttgacac tcatattgga atcttggaat aaatggtcct
     2881 tttccaatag ataaatcaag acagttcccg aaacaaacaa gataacaaaa gctaacacag
     2941 ctaatttggt aaacaaggaa aaacgaaacg gaagcttcgc attggaacgt ttgtataata
     3001 gccattcccg gcactccatc aatacaggaa aaccaattcc tccgacaaaa atcaaaaaca
     3061 tgatcaggat caagaaaaaa tagtcatgtg caaagggctt gatggaatcc ccagtgacgt
     3121 caaacccaga gttcgtgaca gccgatatcg cctgataaaa accgtaaaaa acggcatcac
     3181 gccaacgatc aaaatagcct ctgtaataaa aataaataga aaagaatgtc ccaaaaagta
     3241 attgaaacca gattaaaata gcaaaagtga tccgaatcag tcggacgata ccagacaaac
     3301 gcggttgatt catatccgtc atgatcagct gtcgctgttt cagtgtgatc cgtcgtttag
     3361 aaaaaatgac aaaagcagta gaaatcatca tgatccccaa accaccaact tgaaataata
     3421 tttccagcag tataataccg ttatcattga acacagaatt gatatcaaaa gtcgatagtc
     3481 cagtcacact cactgtactg attgccatga acagcatgtc cacaaaagaa acatggctat
     3541 ctggttcgcg aaaaatcggc atataaaata gaacgagtga taagaccgtc atcaatatat
     3601 aataaaaaac gatgatttgg atcgatgaga aatgattggc agcaaacttc tgtcctcgcc
     3661 gctgcagcct tcgaaagaat aaatcaacat gcacagtact atcctcctga caatagtcgt
     3721 ttctaccagt atacaagggg aattaggaat actcaaagaa attatcaaac agataacaat
     3781 acagctttcg attaaaatag aaatggctta taataaggaa aatcctagaa aaaagaagga
     3841 ggaggaataa caaattgatt aatgctcaac aaatcgtaga aaaaatgaaa aatcaaaaaa
     3901 taaattatga tacagttctg aaaaaaatga tcatgcaatg ggagaaagaa gaagtaaagc
     3961 ctaagatatt aatacataca tgctgtgctc cttgcagtac gcacacattg gaattcatgt
     4021 ctcaatatgc agagatcacg ttattttttt caaattcgaa tattcatcct aaaagtgagt
     4081 atttgcgaag attacatgaa caaaaacgat ttgtagacca atttaatgag aaaactgacc
     4141 atcatgttgc gctaatcgtt gatgaatacc gtccaaatga attcaccaaa atggttttaa
     4201 caaaccatct tgaaaacgaa aaagaaggtg gtgctcgctg cagtgcatgc ttcaatatgc
     4261 gattagatct tgttgcgcaa aaagcgcaag aactaggata cgattacttt ggaagtgccc
     4321 tgaccatctc gccaaagaaa aatgcagctt tgatcaatca gatcggaatg gatatccaaa
     4381 agatttacgg gacacaatac ttgccaagtg atttcaagaa aaacaaaggc tatgaacgct
     4441 ctttgcaaat gtgcaaagag tatgatattt atcgccaatg ttattgtggt tgcgtgttcg
     4501 ctgccaagca gcaaggatgc gatctgaaag aaatcaatcg ggaagcaaaa gcttacttaa
     4561 aaacatcaac cgtagttttt gaggaaaatt aaagaaatct ttcggaaaaa cgtaagaaaa
     4621 aaataaagaa tttatggtag aaataaggta gactgtataa tttgtccgta gtaaagtaag
     4681 gaaacaagaa taaatttcaa tgaaggaaga gataagatgc gaaaagtagc acctattttg
     4741 aagccaatcg ctgtattaac aatctcgacg attgtcgcga ctactacagg tattgtgaat
     4801 agttccagct accgtgcacc aagttcaagt tctagtactg tagaagaaac aacaccaact
     4861 acttcagtct cgacatctga accaacaaca acggaaagtt tgaatgaaac cactacgaca
     4921 agtacatggg acgatacaac aactagttcg tcgtatgatg agacatatac aactgacagc
     4981 tcaagcgaaa caagtaatac ggtaccagat ggcactccat cggattcaac caatccaagt
     5041 acaagtccgg atacaagtgc tagctccgaa acgataccaa gcagtacgac tgtagatgat
     5101 aacacgcaaa atgatgatgc agcacgtaca gcacagcaaa accaagattc aggaaatacc
     5161 caaacgtata accagcaagc aggtgattct caatgacatt tttactagac cttatcaacg
     5221 gggtgcataa attccttggc tatttagaca tcagtcctaa atatcttaac cgtggatata
     5281 cgattttaag tgtgattccc acgctttatt tattgagaat tgtttatgga ctttggcaaa
     5341 accaaaacta tcttcaattt ttcttatatg gacttgcatt tctagtgctt gtttatttta
     5401 ctgttttaaa tgtattttat tactttttag ataaaaacac gaaagccgat gtcactcagc
     5461 tttttgtgaa gtatttacct gatgaagcgt tcaacatcca gacagaagaa tcgatagata
     5521 atggaaattc gatcgataaa gtgaatacac aagaggtcat ggtttcttat gacgaagatt
     5581 atcaattgaa attagccgag aatatgcggt atttgattgg aaatggtgag atcaaaacaa
     5641 atgaactcgg tcgcatggat ggatttctgg tcgatagaaa tacattgtat ccttattact
     5701 atgtcaagaa aacaggagag aaagagtatg ttctaaatat tggacgaagc tactcggaca
     5761 tggaaaaagt agggaccatt cgacttgact caacagaaga cacattggaa cctgtcggat
     5821 tgttcatcgt cggcggtgat tttgtcaaag acgggttacg ctatcatgag ccttatcgtc
     5881 tgaaattgat tgcaaaaaag gcacagtcgc aggaagaacc agtggtttat agtcgtagcc
     5941 aaagaagaag acattcataa tgtgatgaaa cgccgtgtat cagtggttgc gataaaaacg
     6001 tttattcgga ataaggggga tgtgacacgt cttttgtcac gttccttttt tatataacga
     6061 gaaagataag acgaacacat cacttattct ttcctttcat ttataaacat tgtagaataa
     6121 agaaagtaca acgaagtatt gtgaaaaaac gtaataaata acgaggaaaa tacaagtagg
     6181 aggtaagctg tgaaagaatt tttgaaaaat tgggggattt tgatccttgt attagcggct
     6241 attttattag ctagagtgta cgtgtttaca ccagttactg taaacgggca ttcgatggac
     6301 cctacattaa gtgatggaca acgattgatt tcatctaaga tctcaaacta tgaacgaatg
     6361 gatattatta ctacaaagga accgggggat gaagaacgga tgattgttaa acggatcatc
     6421 ggtatgcctg gagatacagt caagatggaa aatgaccagt tgaccattaa tggcaaaaag
     6481 tatgatgaac cttatctgga tgagttcaaa aaagaatttt cagaagataa gttacaagga
     6541 gaatatgctt atagctcagg attccaagca caagcagaaa gttcatccac ctttacgagt
     6601 gactttgaat atactgtgcc aaaaggaaag tatcttgttc taggcgataa ccgcttgatt
     6661 tcaaaagaca gccgaatgtt tgggttagtc gacaaagata tgatccaagg aaaagttgtt
     6721 ttccgttatt ggcctctttc agaaattaaa atcatgtgat gaaaaaataa aaagaagctg
     6781 tgacatgttt tttgtcacag cttctttttc cgaaaattcc ttcttatttc ttggagttgc
     6841 tcactttttt tgcaatctca ttttaagctt tttggctgat ggataagaaa agcgaagcgt
     6901 ttttgttcat aaatagcttt tccccacgat ggaaggtatg actagtagca gagacaaagc
     6961 ccgttttttc caatcgatta ttcaattctt cttggctaaa gccattatgg actttcggat
     7021 gactaatttg ttcattcttg tcaaagtcta cgatgatcaa ttgaccgcca ggagctaaaa
     7081 tttcataaag ttttgtaaga atattctccg tatcaggaat gtgtaaaagt acaagtgata
     7141 gaaggatgag attagcttgg acagcaggaa attcgacaga agcatcagcg tggatcgttc
     7201 ggacattttt cagatctgct gcttggatct tttcttctgc cattttcagc atagtttctg
     7261 aagcatcggc aatgatcagt tctttgaatc tttccgcaag cggtaaacta acaagcccag
     7321 ttccgcctcc gtaatccagc aggacttttt ggtggctgtc gcgcggtaga taagtagtta
     7381 gttcttcgcg aataatcttg gctaatgctt gacggtcagg ggaatcataa tggttagcga
     7441 tggaatcaaa aatatttttt gtcatcaaat agctccttac gtaaaacttt gaaattttaa
     7501 cttattatag cacgtgaaaa gaaagaaagc atgctatact caattcaaaa agggagaatc
     7561 tagaaagaat atgccgatat cgtttgtaaa agatagagag gaaaaaggaa agtgtgtccg
     7621 agaaatatta ctagacttgc ctgagtggtt tgggcttcct gaatcaacgg aaaaatatat
     7681 cgaggaatca agtaaactac ctttatggtg tgaaaaaaga aaagaagaat atttaggctt
     7741 tatcactctt tcacagacaa gtgaagatac tgccgaaatc tattctattg tatgggaata
     7801 aaaaaagact atcatcacca aggattagga acaaaacttt ttaaagaagc agaaggttac
     7861 gcagcaaaac attacaaata tttgcaagtg aagactgtag acgaggggca ctactctata
     7921 tatgatcaaa ctatttgttt ctacgaatca ttaggatttt caaggttgga agtttttcca
     7981 aatttatggg atgaatggaa cccatgttta gttcttgtca aaaaattgga acaaaagtga
     8041 gcaatagatt taatactaat ctgtgcttga tgaaaattct cactgtaaaa aatgctgaaa
     8101 atcaagtata ataccatagg aacaaactgg aaggtgaaaa agagcatggc acaactattt
     8161 tttaagtatg gcgcaatgaa tagcggcaag acgatcgaga tcctaaaagt cgcacataat
     8221 tatgaagaac aaaataagcc agttgtctta atgacaagcg gtattgatac aagagatggt
     8281 ttaggcgttg tttcaagccg aatcggactg aaacgtaatg cgatgccgat atttgaagaa
     8341 acagacgtat ttgacgtaat tcagaaaatg gaaagcaaac cctattgtgt gctgatcgat
     8401 gaagcgcaat tcttaaaaaa gaaacatgtc attgctttta cgagaattgt ggacgaattg
     8461 gatattccgg ttatggcatt tggtttgaaa aatgattttc gaaacgagtt atttgaagga
     8521 tcaaaatatt tattgcttta tgcagacaaa atcgaagaaa tgaaaacaat ctgttggttc
     8581 tgccacaaaa aagcaatcat gaatttacat tatattgatg gaaaccctgt ttatgaaggc
     8641 gatcaagtgc aaattggcgg aaatgaagct tattaccccg tttgtcgaaa acattacttt
     8701 cacccatcaa tgattacaga aggagaataa gcatgtacga tcaattacaa gcaattgaag
     8761 accgttatga agagcttgga gaacttttaa gtgacccaga agtgatttct gatacaaagc
     8821 gttttatgca gctttcaaaa gaagaagcaa acacgcgcga aacagtcgaa gtttatcgtc
     8881 gttataaaga agtagtacaa ggaatcaccg atacagaaga actgcttggt gaaaaactgg
     8941 atgatgaaat ggctgaacta gcaaaagaag aattatctga attaaaaaaa gaaaaagaag
     9001 tcttagaaga aaaaatcaag atcttgcttt taccaaaaga tccaaatgac gataaaaata
     9061 tcatcatgga aatccgtgga gcagcaggcg gagacgaagc agcattattc gctggcgatc
     9121 ttttcaatat gtaccaaaag tatgctgaag cacaaggctg gaaaacagaa gtgatggaag
     9181 ctaacgttac cggaatcggt ggatataaag aagtgatcat gatgatcacc ggagacaacg
     9241 tatattcgaa attaaaatat gaaagtggtg cgcaccgcgt ccagcgtgtt ccttcaactg
     9301 aatcgcaagg gcgtatccat acttccaccg caacagttgt cgtgatgcca gaagctgaag
     9361 aagtagagat cgatattgaa gacaaagata tccgtacaga tatctatcat gcttcaggtg
     9421 ctggcggaca gcacgtcaat aaaacagcat ctgctgtacg tttgactcac ttaccaacag
     9481 ggatcgttgt tgctatgcaa gatgaacgtt ctcaaatcaa gaaccgtgaa aaagcaatga
     9541 aaatcttgcg tgctcgtgtg tacgataaga tccagcaaga agcacaaagc gagtatgatg
     9601 ccaatcgaaa atcagcagtc ggaactgggg atcgttcaga acggatccgg acgtataatt
     9661 tcccgcaaaa tcgtgtgact gatcatcgta tcggattaac tatccaaaaa ttagatcaga
     9721 ttttagcagg gaaattagat gagatcgttg atgcattgat catgtatgat caaacatcaa
     9781 aactggaagc tatgcaaaat gggtaaaatg acctatcgag aagtcctgtc acgggcttct
     9841 tcttttttag aggatcatgg gaaagaagca tatagtatcc aatttttatt tttggaacga
     9901 aaacaatgga aaaaacttga ttggctcctt catatgaacg aagagatttc agaagaagaa
     9961 cagcggttga tcgaaaccga tctgcgactt ctgcttgcag atcatccacc tcagtatttg
    10021 ctaggatatg cagattttta tgatcatcgg ttaaaggtaa ctgaagcaac actgatccct
    10081 cgaccagaaa cagaggagtt agtcgaatgg tgtttagacg agacgcctgg tgtaccgtta
    10141 gaagtgatag atattgggac agggactgga gcaattgcta ttagtttgaa agcagcaaga
    10201 aaaaattggc atatatctgc tgtggatctt tcagaagaag cattagaagt agcgaaagaa
    10261 aatgctcaga aagaaggaac gaaaatcagt ttttatcatg gagatacatt aggaccagta
    10321 atggatcagc aatttgatgt gattatttct aatccgccgt acatcagtcg gaatgaatgg
    10381 gaactgatgg atgaaagtgt ccggtcattc gaacctaaaa tggccctttt tgctgagaac
    10441 gatggattag ctatttatga aaaaatagca gttgaagcac caagcgtact aaaatcaaat
    10501 ggaaagattt ttttagaaat cggatttcgc caaggtgaag cagtaaaaaa aatatttcag
    10561 caagcatttc cagataaaaa agtggcgata aaaaaggatc tttttggcaa tgaacgaatg
    10621 atccaagttt atggttgaag ttgtggatga aaaatttttt atttgttttt ttattataaa
    10681 aaaacactta tttgacaagg atgtaaacga ctttttggtt tatcaacaag tttatccact
    10741 attgacaaat agattatcca caaacagtgg aaaacttgag gataaactca gacaaaataa
    10801 gaatgtatga aaaaggggtt gtggataaac tgtggaaacg aaacgatatg atgaaacaga
    10861 attgcaagag gcagccgaag cactgaaaga aggagaactt gttgcttttc ctaccgaaac
    10921 agtatacgga ttgggcgcca acgctctttt accaaacgct gtcaagaaag tgttttctgt
    10981 aaaagggaga ccgcaagata atccattaat cgtccatgtc gcctcttttg aacaagtaaa
    11041 agagtatgtg gacaactttc atccggcagc agagaagatt gtgaagaact tctggcctgg
    11101 accattaact ttgatattta agatcaaaaa agacactttg ccctcagttg tgacgggagg
    11161 attatccaca gctgcatttc gtataccgga taacaaaaaa acactagaag taatcgaact
    11221 ttccggtgtt ccgcttgtcg gtccaagtgc aaatacgtcg ggaaaaccaa gtccaacgac
    11281 tgcagatcat gtatatcatg atctacaagg aaaaattacc gggattattg atgatggagc
    11341 tacgcgaatt ggtgtagaat ccactgttct tgatttaagt gatccaacag ccatgcctat
    11401 gattttacga ccaggtgcag taacgaaaga acaaatcgaa gcagtcatcg aatctcctgt
    11461 tgctattgat cagcatcttg taaaagaaaa tgaaacacca aaagcccctg ggatgaaata
    11521 caaacactac tcacccgata cacgtgttct gatggtcaga gatggcgatt ggtcaactgc
    11581 agttcaatgg gcaaaaaata agaagatccg tgcaggtgtc atagcaagcc ccgaaattgc
    11641 ggatcaagtg cggacagata ctgcagctgt ttatatgtat aacgacaact cagtagaagc
    11701 ggcggctaaa ggattgtttg caggtctaag aggattagat gaaccaacac ttggattaga
    11761 tttgattttt gtacaagtgt atccagaaac tggattgggg aatgcttaca tgaatcgctt
    11821 gaaaaaagca gcaggacaaa attattttga aaaatgatca attggttatt gtcgcattct
    11881 tttagtatga tacaatgcta tcaagtaaat cttctatcag tgaacgaaaa actaagcgta
    11941 actaatcgta atagaagaga tacgaatatt tggcaatttg tttttgatgg gaaaaataaa
    12001 attgtaggaa aataaaaagg agctgttgtt tgtggtagat tacaaaacgt ttgaccctga
    12061 tctttgggct gcgatcgcca aagaagaaga aagacaagaa cataatttgg agctgattgc
    12121 ctctgaaaac tttgtctccg aagcagtgat ggctgcacaa ggaagtatct tgacaaataa
    12181 atacgcagaa ggttatccag ggcatcgcta ttatggtggg tgtgaatttg tcgatatcgt
    12241 tgaaaattta gcgattgacc gtgcaaaaga attattcgga gcgaaatttg cgaacgtcca
    12301 gcctcactcc ggctctcaag ccaacacggc tgcttatctc gctttggtag aaccagggga
    12361 cacgatctta ggaatggatc tttccgcagg cggacatcta acacatggat caccagtcaa
    12421 cttcagtggc aaaacctatc actttgttgc ttacggtgtt gatccgacaa cagaagttat
    12481 tgattataat gtggtacgta ttttagctag aaaacatcaa ccaaaattga tcgtagcagg
    12541 tgccagtgct tacggacgaa cgatcgactt tgcgaaattc agagaaatcg cagatgaagt
    12601 aggcgcaaaa ctgatggtag atatggcaca tatcgcagga ttagtagcag caggacttca
    12661 tcctaatcca gttccttatg cagatatcac aacgactacc actcataaaa cattgcgtgg
    12721 ccctcgaggc ggcatgattt tgacaaacga tgaagcatta gcaaaaaaaa taaatagtgc
    12781 ggtatttcct ggtattcaag gcggccctct agagcatgtg attgcgggta aagcagtagc
    12841 attcaaagaa gcattagatc ctgcatttaa agaatatagt gaacaaatca tcgccaatgc
    12901 aaaagcaatg gtcaaagttt tcaatcaagc aattggaacc agagtcattt caggggcgac
    12961 agataatcat ctgatgttga tcgatgttcg cgagttaggt ataaatggaa aagaagcaga
    13021 gagcattttg gacagtgtga atatcactgt aaataaaaac tcgattcctt ttgaaacact
    13081 aagtccattc aaaacaagcg gtattcgaat cggcacgcca gcaatcacta ctcgcgggtt
    13141 caaagaagaa gatgctgtaa aagtggctga actagttgtc aaagcattac aagcaaaaga
    13201 tgataacgct caactagacg aagtcaaaac aggtgtacgc gaattaactg aaaaatttcc
    13261 gttgcataaa aaataaaaat ttaaattcca ttagtaaaca gaaaagttca atgttgggct
    13321 tttctgttta ttttttggga aaacggattc tttgacaata tcggtgatgc tctctagtat
    13381 atgaggtgta attttagtct tcacactaaa tctcagggag gaaaagtcat gactgatcgt
    13441 atctcgttag aaaaggaagc agtagcattc agtgatgcaa atgcgcctca tccgcgtatc
    13501 tatgaactag caccggaaga aggaagagtt ttactagaag aagtacaaga atcacctgtg
    13561 aacaaatatt ccgtcgatat tgaagacttg atggtggata ctggcgaatg gggaaaactc
    13621 aatattcgtc tcgtacgacc agaagggaat atggataaat taccagttat tttttatatt
    13681 catggagcag gctgggtttt tggcagtgct caaacccatg ataaattgat cagagaactt
    13741 gcggttcgta cgaattccgt cgttgtcttt ccagaatata gtcgatcacc agaagcaaaa
    13801 tatccaacag caattgaaca aaattatgct gtgttgcaac agctgaataa attagccaag
    13861 tcaaaaaatc tggatctcga gaatctaatc gttgcaggag attcagtagg tggtaacatg
    13921 gctacagtca tgacgatctt aacaaaagaa cgaaagggcc tcccaatatc caagcaattg
    13981 ctgtattatc cagtcacaaa cgctgatttt gatacagatt cctatcatga attcggagaa
    14041 aactattttt tgacaagaga aggaatgatg tggttttggg accaatatac gacgaatgaa
    14101 gaagagcgtg ctgaaatcac agcttcgcct ttgagagcaa atataaatga actaaatgat
    14161 cttccttcag caatgatttt aacgggagaa gcggatgtat taagagatga aggtgaggct
    14221 tatgcgcgca aacttcgtga tgcaggggtt cctgttacac aagtacgctt ccaaggaatc
    14281 atccatgatt ttgtcatggt aaatgctatg gatcagacaa aggcaacgcg tgcagcaatg
    14341 gcattatcta cttcttggat caagaaaaaa gaataagctt tgcttgtccg caggaaaact
    14401 tcttttcaaa aacggatttt cttaggaaaa atggcgagtt tgactagtca atcacttgat
    14461 tttgttttac aattaaaaag aaacgacaga acaaaggaga gcttaaaaaa tgggcaaatt
    14521 tcaagtgatc gatcatccat tgattcaaca caaactaact attattcggg acaaaaactg
    14581 cggaacaaag gtttttcgtg aagtagtcga tgaaatcgct atgttgatgg catatgaagt
    14641 atcacgggat atgccattgg aagacatcgt gatcgaaaca ccgatcactg aaacaacaca
    14701 aaaaacgttg tctggtaaaa aagtagcgat tattccaatc ttgcgcgcag gtattggaat
    14761 ggttgacggt atcttggaat tgattccagc tgctaaagtg ggacatatcg gtctttatcg
    14821 agatgaagaa acattggaac cacatgaata tttcgtcaaa cttccagaag acattgatgc
    14881 acgtcagttg tttgtagtag atccaatgtt ggcaacaggc ggatcagcaa tcatggcaat
    14941 cgatgcattg aaagaacgtg gcgcgtcgaa cattaaattt gtttgtttgg tagcagcacc
    15001 tgagggagta aaagctttgc aagaagcgca tcctgatatt gacatctata cagcttctct
    15061 agatgaaaaa ttgaatgaac atggttatat cgttcctgga ctaggggatg cgggtgaccg
    15121 tttgtttggt acaaaataag taaatacgaa aaagggtgtg acacaacttt tgtcacatcc
    15181 ttttttggtc atttttaacg tttgatgcag aacagctttt tcacagcttt cgtttgcata
    15241 taaaaaaacc atcccaaaaa tgcagagatg gtcaaattca aatctttttt agttctttgt
    15301 agttaacgat tactacaccc ttactttgcg tcatcaagtt cgcattttct gcagtttcat
    15361 caatctcaac aacagcggaa tttttcaatt gctttgaaat cgttccagtt tgcgacttgc
    15421 cgtgaattgt gaacattacg tgagtattga tcttgaattt ttcaccaatt tccgatggta
    15481 cgatagttgt atcaaatttt ccaaaagttg ccattttcat aaaacctgcc tttcacatca
    15541 attataccac gttttatgaa aaatatcatg aaattaaact aattttccat cggactcttt
    15601 acaatcagcc aaatagagta tataatttct tttggataag gccagcttag ctcagttggt
    15661 agagcaacgc actcgtaacg cgtaggtcgt aggttcgatc cctatagctg gcattaaaag
    15721 agaagacaga tatatcaagg atttttaatc cattgataca tctgtctttt tgtttaaagg
    15781 aaataaagta tgctttctta gcaatagagc atgtattatt tctataaaaa tttaggagaa
    15841 taaaacgact agcaatatag ctgtgaaatc aaatatcaca tgaactgccc aacttgtaat
    15901 gatcgagttg cttttaatgg cagcttggtt gaataacaat cttgccaccc cttgtatcaa
    15961 aaggatgtgt gctacagtgt gtaaaatatt tccattatca taagtactgt aatggataaa
    16021 tccaaagatg attgctgaca agaaactagc gacaggaatg ctgaacttac tagaaaaaat
    16081 agcgagaaaa tacactgaga acaattcttc tccaagtatc atgataggca aaataataaa
    16141 taataacggg ctgaaagcct catttattgg attgcctgtt aaaccccatt tcaaaatttg
    16201 ttgcaaaaat accgagactg cggcactgat tactacattg ataaaaaaat atttggctat
    16261 atttttgaca ggagcgacag gtttcgagaa catttttttc gtatcttttt taccaaaaac
    16321 aagtgtaaat gctataaatc cagtgatagt taaagaaaaa atgctaataa tggatggcgc
    16381 aaatagcaac cctaacaaac cgagtacaac gacaatagtg cccaatatcc cttttttaag
    16441 ttctattttt tttcctaaaa tgttattcat gataataact cctactattc agtttttgaa
    16501 gatagagtca gtatacatga agagttaaaa taggcaatgt ttttttatgg atatttgtat
    16561 tgctaaaaat ttatcttata tattcatttt gattatacta cttttatttg taaaaatttt
    16621 ctagcaaaac caagtgcttg caactgatta agcgtacaat tttttagatg ttccgagcgt
    16681 acttcaatca tttcaaagga gttgctactt aaatcgatat tttttaaatc agtatcaaaa
    16741 aagctagcat tttctaaatc attagtagaa aacattattt tagtgaggga acagtctaca
    16801 aaatctgcgc ttgataagac agagtgctca aaggtacttt cttttatgtt tgaaccagat
    16861 aaatttacat agtccatttt acaattctcg aataacgtgt tcccaatata actttccatc
    16921 aatttagtac ctgttaattt acaattgaca aatttcacgc gatgcaacat gctttttgtc
    16981 aatatacagc ctgaaaaatc acagttttcg aatatacagt cggtaatctc cattctttga
    17041 aaatcattgg aagcaaaaaa tgcatacttg aaaatagatt tgtaaataat tggatggcag
    17101 attatttggt tttcgatgac ctctttttgt gaaaggatat tatacagttc aaaatcttcg
    17161 ttttcataga tatgaaaaaa ggatccttta ttcaagcttg cttcattaac tttaggaaaa
    17221 atcatattta attacctcca ttttcataaa gtcatattaa caaaagctaa accaacttac
    17281 attagcagaa aatgagatag gttttcgcct ttttcgataa cgatagtgtc gctatctctt
    17341 gaaacgttct tagaattgcc ctgagagaca caaattaggc gtaattctaa taaaaatctt
    17401 agaataaaaa tttttactga tttaatttag aatgttttta aaataaaaat cgttgccata
    17461 acagtgtatt gaaaggtttt aacaatccag taatgattta aaaaaatcta gatgtagcgt
    17521 atactttgtt tatagaatgt agtgggaaga aatatatttt tgggaggaaa tcgtgatgtc
    17581 taaaagtgaa gaaatagaaa acatggtact aaaattatat gatctcgttt taaatccaga
    17641 gatcaaagaa aaggaacgta tacttttgat agacgcaaag acaggcttag aaaaaggtca
    17701 gtattatcct aaagtcataa ataatttgga acgtagttta cgtccgttag caatcagggg
    17761 agaattgtct aaaccagtat caccgtttta tatggagata tcaacaatag gaaaatttga
    17821 aaaagaatta ggtcgaggaa tggcttcggc accgattact tttgggcatt tataaaaacg
    17881 agttattcat ctcaatgaat taaaaagtat agtcaatctc ataatgcagg ctaggttcat
    17941 ttatttgaac agagtctgta tttttttatt ctaaataaag aaacagatgt ttctttatat
    18001 tgtattttat cctttaatta acacaaaaac agctagtata aactaataat gttaattaaa
    18061 agtgtatttt atgaaactat cgttatttat taatgttgca tttttgtaag ttaaaaattg
    18121 gaaatataga ttgaaaaaat gaaagcaata agtaaaataa aatgaatata tgcgaaaaaa
    18181 taatttacat taggaaaaac cttgtaaaaa cagttttttg gcatatttat tttttataaa
    18241 tatttgtaaa ataactatca attttttagt taaaagattg gaaatgagtg ggggaggaat
    18301 tgaagaaagg atttttgaga gatgatatag taggttttat ttttagttaa aataggggag
    18361 atagaaaaaa tgaaaaagtg tagaaatatt attttatcaa tgttatttat tattactaat
    18421 ataacatcac tgattcctgt tcatgtctat gcggatgcag gcagagatat cagcagtaat
    18481 gtcacttcgt tgaccgtgga cccaacgaat attacagatg gaggaaacat aaaagtaaaa
    18541 ttctcgtttg acgaaaaaaa acaaaatatc caaccaggtg attatctttg gatcaattgg
    18601 ccaagtgaag gaaatattcg cggtgaagga ttccaaaaag aaatcccatt aatgattgaa
    18661 aataaaaatg ttggaacttt aacggtcaga aaagattctg cgcaggttgt gtttaatgaa
    18721 aatattaaaa acctagactc agtagaaggt tgggggcaat ttgagataca ggccagaaac
    18781 gtaaccgata ccggtgaaga aaatacggga ccattcaccg tgacgagcgg tgataaaaca
    18841 gctactgtaa atgtgacaaa gccagcttct ggttcttctt ctagcgtttt ttattataaa
    18901 acaggagaca tgctacctga agatactaag cacattcgat ggtttttgaa tattaacaat
    18961 aacggcactt atgttgaaca accagttaaa atcagtgatg aaatccaaag tggacaaaga
    19021 ttagatccaa gtacgtttga aattaatcaa atacacttag gtgaacagaa ggtttataga
    19081 ggagaagagg gaatccaaca atttttacaa gatttcccca gcgctacatt taatttttca
    19141 gtaactgata attacattga aataactata ccaaaaaact ttgtcaatct taggaaaata
    19201 atggtgagtt ataagacgat catagaaaac ccagaacaaa taaattttga gaatcattcg
    19261 gaagcttggt ttaaagaatt taataaacct gctgttgatg gagaaagttt caatcataca
    19321 gttaaaaata tttcagcttc tggtggagtc aacggtacag ttagaggcga attgaagatt
    19381 ttcaaatata tcaatgacac agagattggt atcccaaatg tgactttcga attaagacga
    19441 gcagatgaac agcctattca aggacagtct agtatcctgt tgacttcgaa tgaacaggga
    19501 gaagctagta tcaaaggcct gcaagtagga gactatgttg taaaagaaaa agaagcaccc
    19561 aattggattg attttgatcc actaagttca aatgaactca aattctccat aaacgaaaat
    19621 gatacagagg gagtcagttt acctatttat aacaagaaaa aggttacgaa catcacagca
    19681 actaaaattt ggaacggtgg aaccactcca agaccgagta tttattttaa attattcaga
    19741 gcaagtacaa acaattggga accagttcct gatgcagaaa caaaacgatt agacaatgga
    19801 ataacttcag tgacttggga agatatccaa cagtatgatg atagtggaaa cgaatatacg
    19861 tttaaagtgc aagaagtaga tcaaaacgga aatgattatg tcccttcagg ttatcaaaaa
    19921 attgaaaacg ggctagtcgt tacaaatgag aataaagaag tcatttcagt ctcaggacaa
    19981 aaaacatggg aagacaatga gaaccaagac ggcaaacgac cgacgacgat cacagtaaat
    20041 ctattagccg acggtcaacc gatccaacac aaagaagtaa gtgaaaaaga tgattggcgc
    20101 tatcgtttca caaatctgcc aaaatacaga gacgggcaag aaatcatcta tactgtaacg
    20161 gaagacaacg tgcccgaata cagtacgacg attgacgggt ataacatcaa aaacagttat
    20221 acaccggaaa aaacaaatat atctatacca ggtagccata taacaccgtg gaaaaatttt
    20281 ccagagaaga cagagagaga gaaaattaga aatctattct ctcaaaaatt gcaaatattt
    20341 gctcatacag gagaatccag cgaacaaaga agcaattata ttagtaagag agctgtacct
    20401 aaacagataa caaataaatc aaaaagcatt cttcctaaaa caagtagtaa aaaatctagt
    20461 tttgctgtaa tcattggttt attgatagta actatctgtg ctgggatatt cttacaaaaa
    20521 tataaaaaag tttagttaga atataatatt ttttgttaaa tatgactgaa atcaaaagaa
    20581 taaaattccg atttataatc gaaaaaagaa gcatttttat atatgcttct tttttcgtag
    20641 aatcaataaa tatggatttg gctaactatg gaagaatact cgtattagtt ttcagcgttc
    20701 atactagttg ttacattgtt tgattggcca aaagaatttc tgatatattt tgtgctaaat
    20761 aaagaaaaag acgcttgaat tgggaaataa gaaaactact ctatcattac aaattttcat
    20821 aaactggcag atgttctaag taaacaagta tcttttcaaa gtcggaaaaa tccataatca
    20881 acgtagtggt attgatattt ggatgaaagc ctacggtatc ttgacgatca atagcagcat
    20941 cgatcacgac ttggattttt ttctctttgt cgtgcatcaa tgctaatgga gtcactgtac
    21001 ctgctggaac gcctaggagg tcaggaagct gttcttcaga aacaaaagat aagcgctttt
    21061 cttttaattg ttcagctagt tgttttaaat cggcgtgctt ttcatcaggc aagatgacaa
    21121 gatagatttg ttttcctttt cttgatttca ataatagatt ttttacttgc ggaccaggta
    21181 gggaaaaagg gacatttttg actgacgtaa tcgcaggatg atcgactttt tgaaaagaga
    21241 tacccagttt ttttagtagt tcataagctt cttgttcggt tgcacgactc atcgcgcatc
    21301 accctccttt ttttattagt gtatcataaa aaagagttga caaatgaaaa ataatcatgt
    21361 aaattacacg taaagttaaa acaaatgaca tcgaaaagaa gagtagccgt taggtgtttt
    21421 tagagagtct ctggttggtg gaaagaggca gcagttaacc gtgaaacaca tcttggagtc
    21481 gattttctga agcgtatagt aggaaaatcc ggggagcccg ttacagctgc ggtcgttgct
    21541 agatgaccag ataaggctgg cttttccgtg aggagtcggt aaaaaaaggt ggaaccacgt
    21601 gattaacgtc ctttgatctt cggatcaaag gactttttgt tttcatctga acggcaacga
    21661 ctgtgtgagg ttttttctgc aaggaaaaaa taaacagagg tggaaccacg tataatacgt
    21721 cctcttggca tttgccaaga ggattttttt attttaaagg aggaaaagaa gatggagtat
    21781 ttgattgaag ttatgccgca attattagta ggagcactca caacattgaa attattttta
    21841 tttaccttga ttggctcatt accattaggg attgttttag cattaggatt gtctttgcat
    21901 tttaagccgc tacgctactt gcttcaaaca tatgtatggg ttatgcgggg aacaccgctg
    21961 ttgttgcaac tgatttttat tttttatggg ttgccgacga ttgggatcgt ttttgatcgt
    22021 ttcgaagcag cactcattgc ctttatctta aactatgcag cttattttgc agagatcttt
    22081 cgtggaggga tacaatcgat tcctcaaggt caatatgaag cagcgcaagt tttgcaatta
    22141 agtccctttc aaacggtgac gaaaatcgtc atcccacaag tgacaaagat tgttttacct
    22201 tctgtaggga atgaagttat caacttggtc aaagattctt ccttgatcta tatattaggt
    22261 ttaggtgacg taatgcgtgc tgggaaaatc gcgatggaac gcgacgcgac tttactgcct
    22321 ttgctaggcg tggcaatcat ctatcttaca ttgactggta ttctaacaat cataatgaaa
    22381 caagttgaag gaaaattaaa ttattaccgc taactgatag gaggaagaaa tatgattgaa
    22441 ttgaagaaag tgaacaaagc atttggtgaa aaaaaaataa tcaaagattt gaatctaatc
    22501 attccagatg ggaaaacatt agctatcgta ggtccttccg gtggcggtaa aaccacgctt
    22561 ttacgtatct tggctggctt agaaagttct gacagcggag aattttattt agacggtgta
    22621 ccgttcaacc cattcgagct taaaatgaaa gaacaagttg taggagtcgt attccaagac
    22681 ttccagctat ttccacatct gaatattttt gaaaacatta ccttagcacc aaaaatggta
    22741 ttgaaacaga caaaagaaga atacaccaaa aaagcagaag aattagcggc ttcattaggg
    22801 attagtgatt tattgaatat ctatccttat cagctttctg gcggacaaaa acagcgggta
    22861 gcgattgcca gagcattggc tatgaatcca cgggtattgg cttatgatga accaacaagt
    22921 gctttagatc ctgaattacg ccagcaagtc gagcgtttga tcctatcatt gaaagaagat
    22981 ggggtaaccc aaattattgt cacccatgat ttagtatttg cagaaaatgt cggtgatcaa
    23041 ttactaaaag tttccccaat tcattaagaa aggagaagat agagatgaaa aaaaccagtt
    23101 ttctattcgc tttgatcgca ggtcttcttc tttttgcagg ctgttcgaac aaaaaaactt
    23161 cagcagataa ttgggcgact atcaacgaag agaaaaaaat cgttataggt ttagacgata
    23221 catttgttcc tatgggattt agagataaag acgggaagct cacaggattt gatattgatt
    23281 tagccaaagc agtctttgaa caatatggga ttacggtaga ctttcagccc attgactggt
    23341 caatgaagga atttgaactg aacaatggaa cgatcgattt gatatggaac ggctattcca
    23401 aaacgccggc aagagaaaag aaagtgcaat ttacaaaacc ttatatggaa aacgatcaag
    23461 tgctgatcac acctaaagaa tcaggaatca caaactttgg acaaatgaat aataagagat
    23521 taggtgcgca aaatgggtca tctggttatg atgtatttac gaaacaacca gaagtattaa
    23581 aagagatagt caaaaaccaa gatgctgttt tgtatgatag ttttaatgaa gcattgatcg
    23641 atctgaaaag cagacgggtc gatggtctgc tgatggataa agtatacgca gactattatt
    23701 tgaaacaaag aaacgaacta gaagacttca acataacaaa aggttcttat gagagtgagg
    23761 attttgcagt tggtgcacgc aagtcagata gtacattagt gaaaaaaatc aatgaagccc
    23821 tagatcaact agagaaaaca ggtgaattcc aaaaaatatc cgataaatgg tttggcgaag
    23881 atgttacgcc gagaaattaa caaatagggg actgtgacaa aagacgtgtc acagtccctt
    23941 tttccgaata aacagtgttc tcctgccaac tccttgtgac tcggagctga atggcaggct
    24001 cacaacctct tggtaaacgg tgttcaaaag ccagtttttc ggtattaagc caaatttatg
    24061 caaaaatgta gaaagccatt ttcacaaaat ttttcttact actcgaaact aagcgacttt
    24121 ttcacaacct cctttacata attttatttt gttgtggaag gggtttcgtg ttattctaaa
    24181 agaggaacga ttgaaggtta taggaaagga agagatgaat ggaacacaaa gaacttacct
    24241 catttccaaa agattttctg tggggctctg cttctgcagc gtatcaagta gaaggagctt
    24301 ggcaagaaga tgggaaagga gaatcagtct gggatcgatt tgtacggata cctggaaaga
    24361 catttaaagg aacgaacggt gatttggcag tagaccacta tcatcgttat aaagaagata
    24421 ttgctttaat gaaagaacaa ggtctgaaag cttaccgctt ctctgtagct tggacacgga
    24481 tttttcctaa tggacgagga gaagtcaatc aagctgggct cgctttttat gagagattga
    24541 tcgacgaatt gattgaaaac gatattgaac ctatgttgac tttatatcat tgggatcttc
    24601 cacaagcatt gcaagatgaa tataatggtt gggaatcacg tcagatcatt gaagatttca
    24661 ctcattatgc agaaacatta tttgaggcat tccgcgggaa agtccattac tggattagtt
    24721 tgaatgaaca aaatatcttc acttcattag gttatttgtt agcagcacat ccgccaggtg
    24781 tgacagaccc gaaacgaatg tatgaagtta accatattgc taatttagca aatgcatctg
    24841 tcatcaataa atttcacgag ttagaaatgc ctggaaaaat cggaccaagc tttgcgtata
    24901 cgccaaatta tccaattgac agtaatcctg aaaatgttct ggctgctgaa aatgcagaag
    24961 acctgatggc caattattgg atggatgtct atatgtgggg aaaatatccg attgctgcca
    25021 tgaggttctt agaagaaaaa ggatgggcac caacgattga agctggcgat gcagaattgc
    25081 tagaatctgc taaaccagat tttcttggga tcaattacta tcaaacggcg acgaatgcat
    25141 tcaatccatt aaacggagtt ggtgctggaa aaatgaatac gacaggaaaa aaaggttcat
    25201 cagaagaaac tggagttcct ggaatgtata aaaaagttga gaatccattt gtcgaacgaa
    25261 caaattggga ctgggagatt gacccagaag gattaaggat cggactgcgt cgtatcacaa
    25321 gccgttaccg catgccggta ctgattacgg aaaatggctt aggagagtat gacaagttga
    25381 cagaagataa acaaatccat gacgactatc gaatcaatta cttacaaagc cacgtcaaag
    25441 ccatcaaaga agcaatttcg gatggagcag aagtcctagg ctattgcacc tggtcttata
    25501 cagatttgct tagctggctg aacggttatc aaaagcgata tggatttgta tatgttgatc
    25561 aagacgaaac acaagaagga tctttggaac gatataagaa agacagttat tactggtacc
    25621 aaaaactgat tgaagaaaat ggagagaacc tttagttcac atacttaaaa caagaaggta
    25681 cggctggata tggccgtgcc ttttcttgat aaaatcattt agaaattaag aaaaactgta
    25741 aaataagctg aaaaatgaaa gaaagcgtca gttctttcaa acaaaacttt agttccctta
    25801 cttttttttg tataatgaaa cttgatgaaa tgagggataa taaatggcac aaaagaaacg
    25861 gcctactaaa aaaaggaaaa agacgaaaaa aacgaaaaag caaaaacagc agcaggaaca
    25921 aatgctgacg attggtgttg ggtttgcctt gattttattt gctgtcttcg gctttttaaa
    25981 attaggtttt ttaggaatat tgattgcaaa cggctttcgg atcattgcag gaaatactta
    26041 ccaaatcctc tgtcttttat tagccgtatt aggattttgg attgtcatta agaatacaga
    26101 gttttcaatt ggtaaaaacc gacgctggtt tggcggcata ctcttttatt tcggtatctt
    26161 attattgtta catgcccatt tatttggcaa actccatact ggggaaccaa atatcatggg
    26221 gacgacatgg gatttgttag ccagtgatat aaaacaaagt caagtagaca ataacgttgg
    26281 tggtgggatg attggagcaa tcctttatca ttttacttac ttcttgattg cacagcctgg
    26341 aagttattta gcagcagtgc tattactggc aggaggagca ttcctgttca gtaatctgga
    26401 aggctatcag ctgttaaatg gtatccaatc aattggagaa cgagtacagg aattattgga
    26461 aggtgatcct gccaagcaag ctcgaaagca agcggcaaag gaagagagaa tgaaacagcg
    26521 cgcagaagcg aaagaagcaa ggcgcttagc tgcaaaagaa gctgcagaaa aagaagctgc
    26581 agaatatgag aagaaaaaag cggtgagcca gcaaagggaa aatactgctg atgaatggca
    26641 ggaaccagaa aatacagagc cggagcagct aagttttgtt ccaatcgaca gttttcaaga
    26701 aaatatccat cctgcgaatc tagagaaacc agtaccagat acaccaaaac agaccaatac
    26761 agcagaaggt ttttcagatg agttgccaga ggatgacggt acctcattag aatttgagat
    26821 tgaagcagaa caggaaaatc aagactatga attaccgaca gttgatttgc ttgattctat
    26881 accaactgtg gatcaaagtg atgagtataa aaaaattgaa aaaaatatcg gcgtattaga
    26941 acaaactttc caaagtttcg gtgtcgatgc caaggtcgtc aaagccagct taggaccatc
    27001 cgtcacaaaa ttcgaagtcc agccggctgt aggggtaaaa gtaagtaaaa ttgtgaactt
    27061 aacagatgat atcgcgcttg ctttagcggc gaaagatgtc cggatggaag caccgattcc
    27121 aggtaaatca ctgattggta ttgaagtacc aaatggaaag atcagtatgg tttcctttag
    27181 agaaatcatc gaagcacaac caaaccaccc agataaatta ctagaagtac ctttaggacg
    27241 tgatgtttct ggacgggtac aaacggctga tctttcgaag atgcctcact tactcgtggc
    27301 tggttcgact ggtagtggga agtcagtagc aattaatggg attatcacaa gtatattaat
    27361 gcgtgctaag ccccatgaag taaaactgat gatgatcgat ccgaaaatgg ttgaattgaa
    27421 tatgtacaac ggcatacctc atctgttgac gccggtcgtg acgaacccta gaaaagcagc
    27481 gcaagcctta caaaaagtag tacaagaaat ggaagaacga tatgaaaaat tcgcggcaac
    27541 cggagtaaga aatatttctg gttacaatga atttgttcaa cagaaaaact tggaaaacgg
    27601 aacgaaacat ccaaccttac cattcatcgt agtgatcgta gatgaattag ctgatttgat
    27661 gatggtagcc agcaatgaag ttgaagatgc gattattcgt ttagcgcaaa tggctcgggc
    27721 agcggggatt catatgatcc tagctactca acgtccaagt gtggatgtta tcacaggaat
    27781 catcaaagca aatgtacctt ccagaatggc atttgcggta tcaagcggta cagattctcg
    27841 gacgatcatt gattctaatg gggcagaaaa gctcttaggg cgaggagata tgctattctt
    27901 gccaatgggt gagaataaac cgatccgtgt gcaaggagca ttcatttctg accacgaagt
    27961 agaacgggtc gttcaatttg ttacagatca gcaagaagct cattatgaag agaaaatgat
    28021 gccgacagat gaagttgaaa cgacaggtgc tccagaacag ccacaagatg agctgtttga
    28081 agaagcaaaa gcacttgtcg ttgaaatgca aacggcaagt atttcccttc tccaaagaag
    28141 atttcggatc ggttacaacc gagcagcacg tttagtagat gaactggaag ctcatggagt
    28201 tgttggcccg tcagaaggaa gcaagcctcg gaaagtattc attgagcagg aagaaacatc
    28261 agaaacgttg ccggacgata atgacatgta aaacttgtgt gatgaagggt tgaaaaacga
    28321 ataaccaata aaaagacaag gcatgatgat accaaaagaa aaaatggttt ttttccatct
    28381 tttctaatac ggtatgatgt cttgtctttt tagtttttgt gagattaaag ttctattcga
    28441 tttatttgtg aagtattgca ttaaggaaat gaatcatgta tagtatgtag cgaaactttg
    28501 agaaaaagag ggaaaatact ttggaaaaac agtccattta tggcttgacg aatgaagaat
    28561 taatcaattg gtttatagaa aacggcgaga aaaaattccg agctgcccaa gtttgggaat
    28621 ggttgtatca aaaacgtgta agtaatttca cagaaatgac gaatctatcg aaacaattga
    28681 tcgaaaaatt atcggagcat tttatcatca atcctctaaa acagatggtc gtccaagaag
    28741 cttcggatgg tacagtaaaa tatttgtttg aactccctga taaaaacatg attgagactg
    28801 tactgatgag acaagaatat ggcttgtcag tttgtgtgac gacacaagta ggatgtaata
    28861 tcggctgtac gttttgtgca agcgggctgc tcaaaaagaa ccgtgatctg actgctggag
    28921 aaattgttgc acagatcatg atggtccaac attattttga tgagcgcaat cttggcgaac
    28981 gcgtttcaca tgtcgttgta atggggatcg gtgagccatt tgataattac gacaatgtaa
    29041 tggacttttt gcatatcatc aatgatgcca aaggattggc aattggtgct cggcacatta
    29101 cagtttccac tagtggatta gcacacaaaa tcaaggaatt cgctaataac ggcttgcaag
    29161 tcaatctggc tatttccttg cacgcgccga ataatgaggt gcgaacatcg atcatgcgga
    29221 tcaaccgaag tttcccaatt gagaaattga tggaagctgt ggatgagtat ttagagaaaa
    29281 caaaccgtcg aatcacgttt gaatatatca tgttgaatca agtaaatgat agaccagagc
    29341 atgcgcaaca attagcagat ctattaaaag ataagaaaaa attagcatat gtcaacttga
    29401 ttccatataa tccagtcagt gaacatgatc aatattctcg cagtccaaaa gctgatgtat
    29461 tgagatttta tgatgtattg aagaaaaacg gcgtaaactg tgtgatacgt aaagaacatg
    29521 gtacagatat tgatgcagct tgcggacaat tgcgaagcaa gcaaatgaaa aaaacagttg
    29581 ccaaataatc gtatcctact cgttttttca attaccataa aaggagcagt tttcttaatt
    29641 aaggaactgt tcaacttaaa taagagaaaa gattctatag cgaaagctat aaagcttttt
    29701 ttgacaagaa aaaccctcat caagcaaaga aatgtcctca atttgatgac agcctgcttg
    29761 atgggggttt tagcaattat ttaactgatt ttcttatatc cttgctggct ttcttgtgta
    29821 gcatgataag tttctacgtc aagaatggcc tgtttaaatt tttctcgggt gatttcataa
    29881 ggcacatgtt taatatcatt tgttgccatg gctttatcta agattgcttc taaatcggtc
    29941 gtgacattga gattcatgtc ggttaacgat actggaagtt ggttcttttt cataaacaca
    30001 tagattttat caaacaaatc gaactgctga tccatcatca ataaggtcag tacaccataa
    30061 ctgacagatg ctccgtgaag gtatccctcc attttttcta gaacagtcgt accgtaatag
    30121 aatgagtgtg ccatagcaga attatagtta ttgttaacta aaacagaaac caatccggta
    30181 gtaacaatga tatccgaaac gacttgttca attgcatatg agggacgatc gtcggcacta
    30241 tctttcaatg cttgcgtacc ataagtcaag agacgatcaa tgcacatttt tccgatttgg
    30301 attcctaatc tatccgtgta gcctagatca tcgccacgag cagaaaaagt agattcgact
    30361 tctttggata aagcatcgcc aatacctgcc cataagtatt tatcaggtgc ttcggcaata
    30421 attgctgtat caatgaaggt gtgtacaggt ggttttgaag gaaagaagag tccgtccatt
    30481 acgccttctt cgttatagat gacacatacc gcagtgacgg gcgaacagtt cgaaccaata
    30541 gtgggaaagg tgaagactgg tttagctagt ttttcaccaa tgacttttac agtatcgcaa
    30601 gcacggccac caccgactgc aaacaggacg tctgcttttt ggacactttc atgctggatc
    30661 aactgttcaa tatttccata agttgaatta cccccgtacc agagactggc gacaacctct
    30721 atttcctgtg tcaaagctac ttttattttg ttttctgcct ttgaaagtgc agtcttccct
    30781 ccaatcagca ctacttttgt cccatattct ttgacgattc catttgcttt ttcatacgca
    30841 tctgttccaa tggtataatt tggtaagaaa acactttgac tcatattcat ttccttcttt
    30901 cttcgttgaa acgggttaaa attttaaaga gtgatcgatc tgactgcggc tgtagatgga
    30961 gtagaggtga acctaagaca ggataagtga tgaataaggt ggcatgaaca ccttgaaatc
    31021 atcaataagt atcctaaaaa cgaacaagta caaaaacatt gaaaacgaca ataatgaatt
    31081 tttgttcctc ttagtatttc taccgattcc ctttgctttt ttgtaattat ctaaaaattc
    31141 taaaaattaa gattattata tgaaaacagg ttttatttgt caattcataa ttggtttttt
    31201 ttaaagcaaa agataatcta tatcatgatg aacaaacaga gttttttcct ccaattgatg
    31261 gctttcctga tctttcctat tttgaataaa gtgtttctgt ataatttttt tattttataa
    31321 gtaagataaa taatgaaaga atagagatac tgattggtag ctaaagattt ttgagcgaga
    31381 acatttcgtt ttttcaaaag gactgttaga ataagcaaga acaaggggga agacgtatga
    31441 taatcagtga atttgaccgt aataatccag tattgaaaga tcagctttct gatttactga
    31501 gactgacttg gccggaagaa tatggagaca gctcggcaga agaagtagaa gaaatgatga
    31561 atccagaacg aatcgcggta gcagcggtag accaagatga gttagtagga tttattggtg
    31621 caatccctca atacggtatc acaggttggg aattgcatcc attagttgta gaaagctccc
    31681 gacgaaagaa ccaaataggt actcgattag tcaattactt agaaaaagaa gtagcttcca
    31741 gaggaggaat cacgatttat ttaggtacgg atgatttaga ccatggaaca acgttaagtc
    31801 aaacggacct gtatgagcat acatttgata aagtggcttc catccagaac cttcgtgaac
    31861 atccgtatga attctatgaa aaattaggtt ataaaatcgt aggtgtctta ccaaatgcaa
    31921 atggctggga caaaccggat atttggatgg caaaaacgat tattcctcga ccaaattctc
    31981 aataataaaa agaggttgtg acagaagtaa tcagcttcaa gaaataagaa ggaatttacg
    32041 aaaattactt cttgaatttt tgtgaaattc caacttattt ccgaagaagc tacttttgga
    32101 acaccgtgta ccagaggttg tgaaaaagtc gcttagtttc gagtagtaag aaaaattttg
    32161 tgaaaatggc tttctacatt tttgcataaa tttggcttaa taccgagaaa ctggcttttg
    32221 aacaccgttt attcagataa gggactgtga caagactttt gtcacagttt ctttttgttt
    32281 attctttttt atctttgtat ggcaataata gacaatataa cgaaaattat ttaatggctt
    32341 ttggaagacc atggaaaacc ttgtacaaag ctattttttc tgaaaaattc cttgaaacct
    32401 cacgaaaaaa tcattatttt atgaaaaaga caaaaaaaag tgttgatttt ttaataatta
    32461 ttcattaaac tcttaaacaa cttcagaaaa tattaattat tctgaaaatt ccaataaagg
    32521 ggtacgtaaa atgaaaaaga aatttacatt tggtttggtt gcggtatgcg gccttgtact
    32581 tgctggatgt tatggcggca gttcagccac aagcagtagt tcagcaaaaa gcggttcagc
    32641 agatggagga ggcgtattta acttagtcgt gcctcaagaa atgcctacag ctgacttatc
    32701 agttgcaaca gatacaatca gttttacagc attgaataac gtttatgaag gaatttaccg
    32761 tcttgatgaa gacagcaaac cacagccggc aggagctagc gagttggcag aagtcagtga
    32821 agacggatta acttacaaaa tcaaattacg agaagacgca aaatggtcaa atggtgatcc
    32881 tgttacagca gcggattacg tttatggctg gcaacgaaca gtagacccag ctacagcttc
    32941 tgaatatgct tacctgtatg cgccagttga aaatgcagaa gacattacag ctggaaagaa
    33001 agataaatca gaactaggga tcaaagcagt tggtgactat gaattagaaa tcaaattgac
    33061 gaaacaaaca ccatatttcc aatatctgct tgctttccca tcatttttcc cacaaaaaca
    33121 atccgtagtg gaagaaaatg gggatgccta tgcatctgca agtgataaag ctgtttataa
    33181 tggaccattc acattagaag attttgatgg accaggaaca gatacagaat ggacttataa
    33241 gaaaaatgat cattactggg acaaagatac agtaaaactt tctgaaatca aagtcagtgt
    33301 agtaaaagaa tcttctactg cattgaactt attcaaagat ggccaagcag atgacgtgat
    33361 cttgtctggt gagttagcac agcaaaacgc aaacgatcca gcttatactt ctgttaaaga
    33421 agcgcggaca agctatatcg aattcaatca acgtgaaaag aattcaccat tcaacaatgt
    33481 gaacctaaga aaagctattt cttattctat cgatcgtgaa gctttagtaa aacaagtact
    33541 aggtgacgga tcagttgtct ctacaggatt gatcccatca gatatggtaa aaagtccaac
    33601 aacgaacgaa gactttgcaa aagaagctgg aaaattagtt tcttatgaca aagataaagc
    33661 aaaagaatat tgggaaaaag cgaaaaaaga attgggcgtt gattctttag aatttgattt
    33721 gatggcttct gatgatgatt catcgaaaaa agtaatcgaa tatgttcaaa actcaatcca
    33781 agaaaacttg gatggcgtaa cagtcaaacc aacacctgtt ccattctctg tacgtcttga
    33841 ccgctcaact tcgggtgatt ttgacgcagt actaggcgga tgggctgctg actatgcaga
    33901 cccaagcagc tttactgatt tgtttgtcac aggtaattca tacaaccgtg gtcgctggag
    33961 caatgcagaa tatgacgaag cagttaaagc agcttcatca acagacgctg gcgatgaaca
    34021 agcccgttgg gatgatttcc aaaaagcaat caagatcatc tctgatgata tgggtgtcgt
    34081 tccggtgtac caaaaagcag aaggtcacct agtgaatgaa aaaatcaaag gtatcgttca
    34141 ccatgcggca ggcgcttcat gggattacaa atggacatac gttgaagaat aatcgttaat
    34201 accgtgagca tgagaaaaaa cgaggctgcg gcaaatgtcg caacctcgtt ctcatattca
    34261 cttatcctaa caaagaaaaa agcatgaaaa tagcagaaag agcaattagt attccggcaa
    34321 tgatcagcca aaagctgtac ataccgtagc tggcagacga gagcgaggaa aattctggtt
    34381 ttttctttcg gttccttgtt cgtgcaagat ggaccgatcg ctgaaaatga tcgaagaaac
    34441 ccgaagaaaa gacccataaa aaaccgccga taatcagaaa cggcaatgac cataagaata
    34501 gatcattaga taattgaatg agtgtaaagg aatggttgat gagatttttt attaaaataa
    34561 ccagaatcag tagaaaagct actgcgtagg ggatagattt ttttttcatt tgattgctcc
    34621 tttatttttg gttcattatc taataatgta gcgaaacatc tgtcagaagt caaaagctag
    34681 ggggaaacat tagtgaatag ttatatcaaa tatgtattaa aacgtgtctt tttcatgatc
    34741 atcacgcttt ggttaattgc aacaatcacc tttttcttga tgcaattgct gccgggcacg
    34801 ccatatacga atcaggaacg tttgagtcct gaaacaatcg agatgctaaa taaacaagtc
    34861 ggtttggata aaccagttat cgtacaatat gggatttatc tttctaattt gcttcaagga
    34921 gattttggaa tttccttcca atttaaaaac cagccagtcg cacatttgtt agctggaaga
    34981 atcggaccat ccttgcagtt agggttacag gcaattatct ttggaacagt cctagggacg
    35041 attttaggaa cgatctctgc catgaagcaa aatacatggg cagatacatc ttctacactc
    35101 gtagcgatat taggtcgttc cattccaaac tttgtatttg ctgttttatt acaatatatc
    35161 tttgcaatca aattacaagt tttgccaatc gcaaaatggg atggctttgt gtacacaatc
    35221 ttaccaacaa ttgcgttggc catgtcgccg cttgctgact ctgctcggtt tatccgtacg
    35281 gaaatggtgg aagtactgca tagtgattat gtggaattag caaaagcaaa aggattgagc
    35341 cgttgggaaa tcgcctttaa acatggtctt cgaaatagtt tgattccatt gatgacttta
    35401 ttaggaccgt tagctgtagc attgatgacc ggatcactgg tggtagaaaa tatctttgct
    35461 attcctggta tcggggaaca attcgttaag tcaatcacaa caaatgatta tcctacgatc
    35521 atggctgtaa cgatccttta ctcatttatg ctgatttttg ttattttgat cgtggatcta
    35581 ttgtacggtc tagttgatcc aagaattcgt gtttcagaag ggagccgagg ataaatggaa
    35641 atgataccaa agcgttatga aacagttgca gatatccctg cggatgaatt tcttccatta
    35701 caaaaaaata ccgaagaaga acgtgaacag attactgcac cttctttgaa ttttatccaa
    35761 gattcatggc gccgtttaaa gaaaaacaaa gctgccgtta tttcaatggt tttactattg
    35821 gtcatcattt tgatctctgt gatcacaatc tttgtttctc ctcatgatcc aactgcccaa
    35881 aacgtggctt atatcaattt gcctcctcgt attccgggaa tcaatatcga tggattgaat
    35941 ggaaaagcaa tggttggtgg tgaacttgtt gataaatatg ctcaagcaaa cgtcccttca
    36001 aacgtaaatt tctttttagg aacagacggt ttgggacgtg atgtattaag ccgcttattt
    36061 atgggaatga gaatctcgtt gctgatcgca tttattgctg cattactaga tgtaacgatt
    36121 ggtgtagctt acgggttggt ttctggtttg ttaggcggac gtgtcgataa cgtgatgcaa
    36181 cgttttttgg aaatcttatc aggaattcca aacctcgttg tcatgatttt gatgttggtc
    36241 gtttttgaac caggaatttt ttcaatcgtg gctgctatgg ccatcacaaa ctggatacca
    36301 atggcacgta tcgttcgtgc acaaacaatg aaattaaaag atcaagaata tgttttagct
    36361 ggattgacat taggtgaatc aagaatgaaa attgcattca aacatatttt gccgaatatc
    36421 tctagtgtca ttattattca aatgatgttt agtattccat ctgctatttt cttcgaagcc
    36481 tttttaagct ttatcggttt aggtcttacg cctccgtcag cttcattagg aacgatgttg
    36541 agcgaagggt acaagacatt cctgtatctg ccttatctat tatggattcc ggcagtaact
    36601 ttatcggtta tcatgattgg ctttaactta cttgctgatg gattgcgtga tgcctttgat
    36661 cctaaaatga aagagtgaag acgatgacga aaattttaga agtgaaagac ttagaaatct
    36721 cttttgatac gtatgctgga aaggtacgag cgattcgcgg tgtcaatttt catttgaata
    36781 aaggagaaac attggcgatc gttggggaat ctggaagtgg aaaatcagtg acgaccagaa
    36841 gcatcatgcg cttgctgtca agcaacgcca atatagatgc tggtcaaatc ctctttaaag
    36901 gtaacgatat cgttggaaaa tcagaaagag agatgcaaaa aatccgtggt aaagaaatag
    36961 cgatgatttt ccaagatcca atgacctctt tagatccgac gatgcccatt gggaagcaag
    37021 tcgctgagtc ccttagaaag cataataaag tttcaaaaaa agagggacaa aaagctgcat
    37081 tagaattgct taaattagtt ggaatacccg aagctgagaa acgtatcaac agttatccgc
    37141 atcagttctc aggaggtcag cgtcaacgga tcgtgatcgc gattgcactg gtatgttatc
    37201 cggaaatcct gattgctgat gaacctacaa cagcgcttga tgtgactatt caagcacaga
    37261 ttttggagct gctgaaagaa attcagacaa aaatcgatac atcaattatc tttatcactc
    37321 atgaccttgg tgtagtagcg aatgtcgctg atcgtgtcgc tgtcatgtat ggaggaagaa
    37381 tcgttgaagt tggaacatcg gaagaaattt tctacaaccc gcaacatccc tatacttggg
    37441 gactgcttgg ttcaatgccg acattagata gtgcgaacga tcgattgtat gctattcctg
    37501 gttctccacc ggatttattg aacccgccaa aaggagacgc attctatcca agaaatgaat
    37561 tcgcgatgaa aatcgatgca gaacaagaac caccattttt tgaactatca aaaacacaca
    37621 aggcagcaac ttggctactt gctccgcagg cacccaaagt gacaccgcca gaagaaatcc
    37681 aacgtcgctg ggctatcttt aaagagaaac aaaaacatac ttacggtcaa ggaggaattg
    37741 ctgatgccaa ataaactact tgaagttaaa ggattgaaac agtatttcaa tgtaggaaaa
    37801 aagaatgaag tacatgctgt aaatgacatc agctttcaca tttatgaagg agaaacattc
    37861 ggtttagttg gagaatctgg aagcggaaaa tccactactg gccgtacgat cattcgcttg
    37921 aatgaaccta ctgatggtga gatattattc gacggtcaag atataacgaa gatcaaagat
    37981 aaaaaaggtt tgacgaaatt ccggcatgat gttcagatga tctttcaaga tccatacgct
    38041 tcgttgaatc ctcgtatgaa agtcagagat atcattgccg aaggaattga tgttaatgga
    38101 ctagctaaat catctgaaga gcgtgcaaaa aaagtcgatg atctattgag aactgttgga
    38161 ttgaatccaa gccacggtac tcgttatcct catgaatttt caggtgggca acgccagcgt
    38221 attggtattg cacgagcatt ggcagtaaaa ccgcgtttta tcatttgtga tgaaccaatt
    38281 tctgcactag atgtgtcgat ccaagcccaa gtggtcaatt tgttgcaaga tctccaaaaa
    38341 gaacatcaat tgacctatct atttattgca catgatttgt cgatggttaa acatattagt
    38401 gaccgaatcg gtgtaatgca taacggcttg ttattagaga tgggaacaag tgatgaaatc
    38461 tataatcacg gtgttcatcc ttatacagaa agtttgttat ctgctattcc tctaccagat
    38521 ccagaccatg agagaaaacg cagaagaatc aaatatcaac ctgaaccaga tgacggacaa
    38581 gtacgtcaac ttcgtgaaat cgcaccagaa cattttgtct atgcaactga gcaggaagtc
    38641 ccatattacg caaaaaaact aaaacgacaa aaggaatctc ttctggttgc taactaggag
    38701 ggacatagat gctaaaagct tttaaattcc gtatgtatcc gacagaagaa caaaaacagc
    38761 aattgattcg tacttttgga tgtgctcgat ttacctataa ccatttgctg aaaaagcggc
    38821 agaaaagttg gcaacaaaca ggagtagcca atttttcgct cacacccgct acattaaaaa
    38881 aagaataccc attcttaaaa gaagtagaca gtcttgcttt agcaaatgca cagcttaatt
    38941 tggatcgggc ttttcgcaat tatttcaagg gacgtgccag cttcccaaag cttaaaacga
    39001 aaaaaagtat gtggcaatct tatacgacca acaaccaaac ccgtacgatc tatctggaaa
    39061 atggctactt aaagttacca aaacaaaaag aactaatcaa gataaatcag catcggccag
    39121 ttgaaggatc gattcgctcc gctacgattt ctgctcgata taatgaagaa ttttatgtcg
    39181 cactactttg tgatgtttcg ccagtaaaaa aagaatcttt agctaaatgg atcgggatcg
    39241 cctatcatcc gaagacattg atccaaacat ctcgacctct agaagtaact ttaccaaaat
    39301 ttcaccagac agaagaaaag ctgcaacatg cacagcggaa attgaatgtg aaagtccgct
    39361 ccgctcacca tagaaagatc aggttagatc aggcaagcaa ttatcagaaa caaaagagaa
    39421 aagtaatgga tctttatctg aaacaaaaga accagcgaga agattatctt gaacaattat
    39481 ctgggaaatt ggtcaaacaa tatgactact tatttgtaga atcttttcca aaagaagagg
    39541 cacatgctga tttttctatt cacgactggc ataaattaat aacaaaattg cgttataagt
    39601 cccaatggta taataaaaaa tttcttttga tcaataccga cggagcagaa gaaagcaatt
    39661 ccgtaagaaa gagccaagta gtagaaaaaa tgggcagaca ttcggttatc aagggataaa
    39721 aaatgaatga aactgatagg agcgttaggg ttagccttgt taataaaaag tcttaatgac
    39781 ttttgtttct aggaattttt cttttgaaga aaagctcact aattatgaca aaccaataaa
    39841 acaatagcag aaaaagttcg tacgagcttt ttctgctatt gttaattttt
//
LOCUS       DAFEEZ010000019        39074 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000019
VERSION     DAFEEZ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.019"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            6..305
                     /locus_tag="LP245_001098"
     CDS             6..305
                     /locus_tag="LP245_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1519028.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="LP245_001099"
     CDS             378..1739
                     /locus_tag="LP245_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBL1519029.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="LP245_001100"
     CDS             1761..2021
                     /locus_tag="LP245_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519030.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="LP245_001101"
     CDS             2035..2787
                     /locus_tag="LP245_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBL1519031.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="LP245_001102"
     CDS             complement(2881..3486)
                     /locus_tag="LP245_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1519032.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="LP245_001103"
     CDS             complement(3539..4513)
                     /locus_tag="LP245_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBL1519033.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="LP245_001104"
     CDS             complement(4891..5610)
                     /locus_tag="LP245_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1519034.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LP245_001105"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LP245_001105"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBL1519035.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="LP245_001106"
     CDS             7161..8558
                     /locus_tag="LP245_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1519036.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="LP245_001107"
     CDS             8639..9079
                     /locus_tag="LP245_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL1519037.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="LP245_001108"
     CDS             9227..9553
                     /locus_tag="LP245_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1519038.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="LP245_001109"
     CDS             9554..10303
                     /locus_tag="LP245_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519039.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="LP245_001110"
     CDS             complement(10383..10838)
                     /locus_tag="LP245_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBL1519040.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="LP245_001111"
     CDS             complement(11265..11540)
                     /locus_tag="LP245_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519041.1"
                     /translation="MKLEDKKVILKKIKRLPEQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="LP245_001112"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="LP245_001112"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBL1519042.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="LP245_001113"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="LP245_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBL1519043.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="LP245_001114"
     CDS             14770..17436
                     /locus_tag="LP245_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL1519044.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="LP245_001115"
     CDS             17800..18552
                     /locus_tag="LP245_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1519045.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELLNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="LP245_001116"
     CDS             complement(18574..19728)
                     /locus_tag="LP245_001116"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBL1519046.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="LP245_001117"
     CDS             19913..22354
                     /locus_tag="LP245_001117"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBL1519047.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22684..23388)
                     /locus_tag="LP245_001118"
     CDS             complement(22684..23388)
                     /locus_tag="LP245_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519048.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23575..23820)
                     /locus_tag="LP245_001119"
     CDS             complement(23575..23820)
                     /locus_tag="LP245_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519049.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23837..24688)
                     /locus_tag="LP245_001120"
     CDS             complement(23837..24688)
                     /locus_tag="LP245_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL1519050.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24854..25858
                     /locus_tag="LP245_001121"
     CDS             24854..25858
                     /locus_tag="LP245_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBL1519051.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26099..26455)
                     /locus_tag="LP245_001122"
     CDS             complement(26099..26455)
                     /locus_tag="LP245_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL1519052.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26823..28010
                     /gene="tuf"
                     /locus_tag="LP245_001123"
     CDS             26823..28010
                     /gene="tuf"
                     /locus_tag="LP245_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL1519053.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYTHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="LP245_001124"
     CDS             complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="LP245_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBL1519054.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(30815..31576)
                     /locus_tag="LP245_001125"
     CDS             complement(30815..31576)
                     /locus_tag="LP245_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1519055.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31854..32375
                     /locus_tag="LP245_001126"
     CDS             31854..32375
                     /locus_tag="LP245_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBL1519056.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            32434..33294
                     /locus_tag="LP245_001127"
     CDS             32434..33294
                     /locus_tag="LP245_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBL1519057.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            33479..35794
                     /locus_tag="LP245_001128"
     CDS             33479..35794
                     /locus_tag="LP245_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL1519058.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            35976..37817
                     /locus_tag="LP245_001129"
     CDS             35976..37817
                     /locus_tag="LP245_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBL1519059.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            37841..38950
                     /gene="rpoD"
                     /locus_tag="LP245_001130"
     CDS             37841..38950
                     /gene="rpoD"
                     /locus_tag="LP245_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBL1519060.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
BASE COUNT        12572 a         6875 c         8094 g        11533 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttgctct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgctaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagccg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttttctctat cagaaaatat
    22441 gtttattatt agaatttttt atagttaagg ttaggcatct taagaaatca ggcaactcca
    22501 agatatcttc aggtagaaga gaagtcgcct aacattgtag gatcataggt gatttgttgg
    22561 acaggtcaag ctgatatttg agcctgatgt tagaaggaat ttctttttac ttgctgtaga
    22621 aattattata tgactaaaaa ggctgggatt ttaaatccca gccttttatg acaaatagaa
    22681 tttttatcga tcagtaatcg ctgtcgctgc aaattgttcg atcaaaggaa tcaaagtcaa
    22741 tttgactttg tatttccgtt cgagtgcttt ttcgataacg aactcatttt cagtagtcat
    22801 agaaatagtt gctaatttac gaggttcatc agcatttttt tcattaataa ctacttcatg
    22861 ttcattttgt tctgtgtaaa atttaggata ctcagcaacg gcttttgaaa aatcagcaaa
    22921 acttaaagcg gcattcgtat cagttgagcg tgtattttca gttgtgtccg cttttggttt
    22981 ttccgttttt tcttctggca cactgactgt ttcttctgta actggtgtcg caacagcttg
    23041 cgcagttggt tcatcgtttt tcaatcgttg atcattccag taagacacga tttcaataag
    23101 aagattgtca cggaatcgtt cgaaaatccc gttttctcct gaacgaattc tctttaatac
    23161 agtattgaag ttgtcatcga ttggcacgtt gatccgtgta tcttcatttg ttttcccagc
    23221 taatccgatc gttaagattt gacggttttt gggatcaagc atgacttgta acggcaaacc
    23281 ataacgtcgc aagctctctt cttctagaga acggaataat tgtcctctta caccatccaa
    23341 tgaaggacgg aattgattta ataatttttg tttctgtttt ttcttcatat gttctctcct
    23401 tcgctcatac cctttcgatt ataagaaaaa aacagccaaa tgaaaaggag taatgcaaaa
    23461 aaacttgcgt atacgcaaat tacaacagaa aaatttgcgt attttcccgt tttttgaaag
    23521 aaaaataaaa aatggaacgg attatgtata tatacataat ccgttccatt ctttctattt
    23581 tttcggtatc aaggcaaaaa caggtagttc aggtgaataa atgacttcat gttcgtgcca
    23641 gggtttgacc attagcgaat gatcgaaccg ttttttcagt tcttcgatga tttgatcatg
    23701 tgtccagttt cttgcaggaa aatgttggat tttctctgca tcgatcaaaa agacaaaatc
    23761 ggaatgaaaa gtctgggtaa cttcttccga gagagaattc aagcgttcga ttggatccat
    23821 aaaatcacct ttcgacttaa aattgggtag tatctgggtc ttttgctttg ccgactacac
    23881 catctaactg atcgatttgt ttcatttctt cttctgttaa ttcaaaatca aataattcag
    23941 tattttcttt gattctgctt ggtgtcactg acttaggaag aggaaggaat tcgtgttgca
    24001 gcgaccaacg caaagcaact tgtgcaatcg tcttgtcatg tgcttcagcg atttgtttca
    24061 tttcaggcac atcgaagatt ttaccagtgc ctaatggact atatgcttcg aggatcatat
    24121 catgtttttt tgcatactca actacagttg tctgtaattc gcctggtgca aggaaaactt
    24181 gattgaccat cggcataatt tttgctgttt ttgctagtgt atctagatgg tggggtaaga
    24241 aattgctcac accgattgct ttgattttac ctgcttcata cagttcttca aatgctcgcc
    24301 atgtatctgc atttgcttgt tcccaattat cacgaaaagc aacagggttt ggccagtgga
    24361 tcaaaaacag atctaaataa tctgtttgga gcttcttcaa tgattcttca aaagaagaca
    24421 tcacaagttc atagctgtgg tttgcattcc ataattttgt tgtcaagaat atctcttctc
    24481 taggaattcc actttcctta atcgcttggc cgacgctttc ttcattcttg tatccttggg
    24541 cagtatcgat atggcgataa cctgcagcca gcgcttcttt aacagaggaa acagcgacat
    24601 ccccatcagg tgtttgccat gtgccgaatc ctactaccgg gatttcgtaa ccatttgata
    24661 gacgataagt gcttgttaat gaattcatac tttcagctcc ttttttattc gttcaactat
    24721 aagtgtagcg catttttcga aaaaaagaat ccattttgtt tctactcttg aaatttttgt
    24781 ttaaaagaaa atgattttga ttctggtatt tttgattttt tttccgtaaa ctaagacaga
    24841 agggaatgag aaaatggata tctatttaaa aaaagcaatt ctgcatatta ttgacagaga
    24901 aactggttct ccagtctttt cacaaaaaga gctggatctg acaaaagaat atattcgtga
    24961 ttttcttcaa aagaagatcc aaaaaatctc ttctgctcaa acaaaaactg gacaactagc
    25021 agaagaaagc atgatcgttg aatcacttaa aatcgctcaa gaaaattttg tggaagcaag
    25081 tgaagcaatc gttcagcggt ggttcgatat ctaccaagaa agtgaagaag cacctagtgc
    25141 agatgtattt gttgtcttgt atgaattaga tacagtgatg tacttatctt tattgaaagt
    25201 caattatcgt gaggcttaca ctcactttgt tgaagcagac gaagcaggga tcgacaaccg
    25261 cttgattttg aatcgagcaa ttctaggggc gaaaacacaa aaagcagatg aagcattcgc
    25321 tgtgaatttg actgattgga cctacgaatt aattgaaaaa aaatatgagt tttctggcaa
    25381 aaaagagctt tatttttctg gaagagtgat cgaaagtgtt cctgcacctt ctttagaaga
    25441 aaatgtaaaa gtgatccaaa aagtagccaa gcatcttgga aaaaaatttg agacagaaga
    25501 atttgatatc atggctgatt tgaaagaagc tgtctatgat acgatagaag aaaaaggtcg
    25561 gttggatcat gagatgattg cggaaaaagt cttcaaggaa aacatcacgg caaaaatggc
    25621 ttttaaagaa gaagtacaag agcaaggatt tgtcccagaa gcacctcctg taaaagaagt
    25681 acaagaaatt tctgagaaaa aatttggaaa acaaaaattc aagctatcaa acgggatcga
    25741 actgatcgta ccagtagatg tatatcgcaa cccagatttg attgaatttg tgaataatcc
    25801 ggatggtacg atatccgtga tgatcaaaaa tgtggatgaa gtattgaatc gtttataaaa
    25861 atgactagaa tattaggtgt tcaagtacca gtgatcagtt aaatgaattg tgtcaagaga
    25921 aggatcggaa aagacgaata taacaaaaaa agagcgtgag acaaaagtaa agaacacttt
    25981 tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt cttatttctt
    26041 ggagttaaac gcttctgtcc cagcctcttt ttatctaata aaattttaag accatttact
    26101 aattatcgat tttttctgcc gcatttttag gcacttcaga agcctttatt tcttcccagc
    26161 ttaatacacc tttacgagga ttgactttga gtttaagata cgcattcatc tttaatggat
    26221 gttctctttc ttcgcgaagc gtcacctgtt ttttttcacc atctttatta taagccgctt
    26281 gcttgtaggt ataagtcgtg aatttctctc cgttatctgc ttgggtagct gacatttcgc
    26341 cattcgtcgt gatttttgta taataagctt cgccgccgta aaaataatga taagctgcaa
    26401 aacttccgcc gagaaatatg cctaaaacga caagtacgcc aattaatttt ttcatgtact
    26461 tcacctcttt ccttattatt aacgaaatag aagatttcgt ctattgaaag ttgttggcaa
    26521 cagctgaatt ttaaactttt cctcattttg ttcttattgc ttcaaaagaa agttaaggac
    26581 tatcttgaag tttttctcaa aaaacacatt tttttattta taaaaggtac ttttttcgcg
    26641 tataagacag acgagtgctc ttagttgact ttgaccaata ttgacgtata ataagcttag
    26701 ttcgaatctt acaaaaagta agtcggacgt attctttttg atttagtcaa aaaaagacta
    26761 taataaaaag gtgagagctg aaatttttca gtgatctata ttatttagga ggtttgtaaa
    26821 ttatggcaaa agaacattat gacagaagta aaccacacgt taacattggt acgattggac
    26881 acgttgacca tgggaaaact actttaactg ctgcgatcac tacagtatta ggcaaaaaag
    26941 gcctagcaaa tcctcaagac tatgctagta ttgatgcagc tccagaagaa cgtgaacgtg
    27001 ggattacgat caataccgca cacgtagaat atgaaacaga aaaacgccac tacacgcata
    27061 ttgatgcacc aggacacgcg gactatgtga aaaacatgat tacaggggca gcacaaatgg
    27121 atggtgcaat cttagttgtt tctgcaactg acggtccgat gcctcaaaca cgtgaacaca
    27181 ttttattgtc acgccaagtt ggtgtaaaat acctgattgt tttcttgaac aaagttgatt
    27241 tagtcgatga tgaagaattg atcgatttgg tagaaatgga agttcgcgag ttattgagcg
    27301 aatatggttt cccaggcgat gacactcctg tgatcaaagg ttccgcatta aaagcattgc
    27361 aaggcgatcc agatgctgaa gctgctatta tggaattgat ggatacagta gatgaatata
    27421 tcccaacacc agaacgtgat acagataaac cattactatt gccagtggaa gacgtcttct
    27481 caattacagg tcgaggaact gttgcctcag gtcgtattga tcgtggtgct gttcgtgtcg
    27541 gtgatgaggt agagatcgta gggatcaaac ctgaaacaca aaaagcagtt gtaacaggtg
    27601 tagaaatgtt ccgtaaaacg ttagattacg gggaagctgg ggataacgta ggcgtgttgt
    27661 tacgggggat ccaacgtgac gatatcgaac gtggacaagt acttgctaaa ccaggttcca
    27721 ttactccaca tacaaaattc aaagcagaag tgtacgtgtt gacaaaagaa gaaggtggac
    27781 gtcatactcc attcttcaac aactatcgtc cacagttcta cttccgcaca actgatgtta
    27841 caggaacaat cacattgcca gaagatacag aaatggtcat gcctggtgac aacgtgacga
    27901 ttgatgttga cttgatccat ccaatcgctg ttgaaaacgg aacgacattc tcaattcgtg
    27961 aaggcggacg gacagtaggt tcaggtatcg ttacagagat cgaagcataa gaaacgcgac
    28021 tcgaatattt tggtaatgaa aaatgtttaa aataaaagag cggtccaaac aggatttctg
    28081 tttggaccgc tctttgttct tcaattgtat aagaagagat tgtagaagca tgaactttcg
    28141 ttttacttca gtctctttta ttcatcatga gagtgttcat ctatcggtat gcagttttta
    28201 atactttctt cgtatccatt ttttcaaacc acttattcta ccttgtgtct gctcaactgg
    28261 cgcattatca ataatcagca aagcaatcat aacatatgca atccaactat ctctagaata
    28321 tagagtataa cgtgagaccc agtttgtagc gtacttgctt ttatattctc ttaatccatg
    28381 gaaagaataa aaatgagaac caaactcgta aaccaagtat gcaatccttt cctgtaaaaa
    28441 actctttctg gaagttccga catttgaaag aggggccatc cctaaattga accattggat
    28501 atgttcttct ttcatatagg caaacaaatg caagaacaag aaatccatac tgccagaagg
    28561 tgctttttta gaatcatatc gcatcagatc aatcgttcct actttattgt tcgtgtaagt
    28621 aggcatgatc gttgcaaaag cgacaatttc ttcttgggta tttttgacaa ctgcaatagg
    28681 cgctctttgt agataatctt cagagaaaaa gcctaaagaa aacccttttt cctttcgtga
    28741 acccaaccaa ttatcagaga tatttttgaa agtactcatt tgctcagtag aaaatggtgg
    28801 ttgtaagaca tcaaatgtaa atccttctcg ttcgatccga ttcaagacag cacgagtgcc
    28861 cttcattttt ttccctgaag ttgtaaaact attcaggtct acataagctt cttcccccat
    28921 cttaatgaaa tcgtagccga attcatgcaa aatcataaca atctcttcgc ttgtttcgta
    28981 gaaaactggt aaatagcata gtcgatctgt ttcttcgata aaagcttcga ttgcttctgg
    29041 aaaatcttct ttcttaccag aaggatcacc cattacaata catttattat tgaagcaagc
    29101 gaattggaga agaacagttg gttcaccgtc tttttcatag gcaaacatcc gcttatcttt
    29161 taagaagatc aattgactat cggagtttcc tccataagtt gtaaggatct tcagggcctt
    29221 ttcttcatta aaggcttcgc caatctgttt cttttctcct tgaaggaaat gaacaaatag
    29281 aacgatcatg aaactaacag cgatgatggc caacaatccc gaaaaccaaa tcttttcaga
    29341 aggaaataag aaaaaggaaa taaaatggtg acgccgatga gggaaatccg gcagattgta
    29401 taccccaata acgatgtaaa gcaaggacag tgcaccaata atgattccat cgatcgtacg
    29461 ccactcccat gaatagatca attgttcccg aaataattcg tttttagaag caagaatgat
    29521 cagaagcaga atagacaaga aaaccaccgg tgtgaaacta aaatcactta ataaaacata
    29581 aagtaaagct agaacaatca agaagattgt aggcaaatat gctcgtttca cacgtgctgc
    29641 gatccctctg cccataatga ttaaaagaaa tcccaatagt atactaggaa attggataat
    29701 aaaatgaaat ttcaatgggt tcaaactatg aagccagcga aactctgtaa aagcttgcgg
    29761 gatagtggca gaaagtacta gcatgattcc agaaaagtat aataagacaa ccacgatttt
    29821 atgcgcaatt tctgttgcta attgtttagg gataccagaa taacgctgat caaaagtgga
    29881 accgatattt ttgaagaaaa agacgattcc aatcaaaaac ggaatgatgt agtagaacag
    29941 gcgatagagc aagatccaca caacgactat ttctcttggc acaccaatag cggacaaccc
    30001 gataatcatc attacatcga aactcccaat ttctcctgga atcatagaca cgattcctat
    30061 cactgaagca gcaatgaata atggaattgt ttgccacaga tcaatccgga tttccattaa
    30121 ataaccaaca gaaaggaaac taaacaggac accggtccat tccaacaatg aaactagcaa
    30181 tagctgtcct tgagttttaa gtgaggtacc accaaggaat cctttctttt tgaaagtagt
    30241 aaataaaaag acgacaggaa aatatagacc gccgccgatc aaccatatcc aatattgctt
    30301 caaaaaagga gcaactggcg tgaagactac aagtaaaaaa gaaagcagac tgtaaataga
    30361 aagtccagcc atcaaaaaca agaaaacttt cgataatgct tggatcacgt ttctgctctc
    30421 tttcttttgt ccatatagtt cagagcgaag ccccacacta acaaacccgc cgaaaccggc
    30481 aatattgttg atcgtattga tcagccagct tgtctcaaac aggtaacgag gattctgctt
    30541 ttgttcaagc atccgattca aaataatatc ataaccaacc ataggtaaca cagagataag
    30601 accaatcaat agcattagtc cgcttttcca tacaggtata gtggcaaacg tttctcctaa
    30661 ttgctggata gatagagttt taccgatgga catcaattca ccgacaataa tgacaatgac
    30721 agaaatcaaa aagattgttt tgaacagtcc taggtggttt ttcagccatt gtatggtatt
    30781 ttttaacaaa taaatcacct tctattccta atagttatgt ttcagaaaga aattgaagaa
    30841 cttctcgatt gaagcgttca ggatcttttc tagctaattc atgtccttgt tctttcacaa
    30901 gcacaaagga agcttttggt atagttttag ctatatacaa agaatgtttt agcttgatta
    30961 catctttttt tcccacgatg atcaaagtgg gggagttgat tttttttaaa tcattttctg
    31021 taagcccgat gtcatgcagc aaaagtttga taactaaaag atttttgcga agacttgggc
    31081 gaaataaaga gagtaaccat acccatgcat aatgaatatt actgatgact ctggcagaaa
    31141 aacgaacgcc tttaacaagc gtgtttccag aatttaaaat caatcgatga acttttttag
    31201 ggaagctgct ggcaaatacc agtgctagat ttgctccatc actaaatcca agaaaatctg
    31261 cctgatcgat tttttccagc aacatgatcg tattcagatc ctcggccatt aactgaaaat
    31321 tcaacataga tgcttcgttt gtcgaacgac catgtcctcg gctatctact agatacacgg
    31381 tatagtagcg ttcgagtaca gggacctgtt ctgaaaaaaa gcggccgctg ccgtcattgc
    31441 catgcagtaa aaagagaggg aagccttgac cgctcttttc atagtaaatt tcgctcccat
    31501 ctggcatttt tgcatatttc ttttcttttt tcacataatc acctactgtg taaagtataa
    31561 cgattatatc agtcattggg caattgtttt tactgaaaaa caacgatcat tttcgtaaga
    31621 tgtcaaaaaa tacaggaaaa ttcatttttt cttaaggcgt acacagaaat caaggaagaa
    31681 atagccaaga agataaagaa atagtaagat aaaaaaagat gtcaaaataa ctaggtgatg
    31741 aaatgaagcg aaaacgatta tctattatcc gtattctttt ttacatgatc attctgacgg
    31801 ttattggtgc ggtgttgttt ttatgaggaa gaacttatcg ttcggtaaaa cgagtggaaa
    31861 gctatcaaat agaaataaca acagctgcaa aaaattatca tatggaaaac tacgagaatt
    31921 tgatcaaggc gataatattg accgaatcaa aaggaaaagg gacagatctc atgcagagct
    31981 cggaaagtct gcatggagaa gctgagatca ttgataatcc agctgacagt attgatcaag
    32041 gtgtcaaata tttggcggaa atgatagtag aagcaaagaa acaaggatgc gatttatgga
    32101 cagctgtcca agcatataat tttgggaaag attatattgc ctatgtaaaa aatcatggcg
    32161 gagaaaacac agtagaatta gcagaagcgt attctaaaga tgtgctgagc ccacttttag
    32221 gaaatgagga agggaaacaa taccgatatt ggcggatcca gtccttgctt tacaatggcg
    32281 gctatctcta tcataatgga ggtaacatgt tttatcctga tattgtcaaa atgaatgaaa
    32341 aaataataga gacctatgaa aaagtcttta agtaaaatag caggaaatgt tcaatcatga
    32401 ataaaattaa atgaaagaag gagtgcgcaa atagtggaaa aaaggcaaaa aatggaaaat
    32461 caagaagtgg ggtacacaac caaagactgg atgttacggt ttgtgaaggg aatgtttatc
    32521 ggttcaggat ttatcttgcc aggagtcagc ggtggtgcat tagcagctgt ctttggcatg
    32581 tatgagcggc tgatttcttt tttagcccac cttacaaaaa atttcaaaga aaatgttttg
    32641 ttttttctgc ctgttggtct aggcggagtg acaggcatct ttctactttc ttttttagtc
    32701 agttttttat taggtgcgta tgaaacaacg atattatggt tttttgtcgg atgtatcgct
    32761 ggaactgttc ctgcgttatg gaaagaagca gggaaaaaag gaagagatac ttctgatgtg
    32821 atcatcatgg ttgttacttt tgttctggct tatttgtttt tattatacgg cgctcaatta
    32881 tttgacgggc aagtcgatca gaattttgga acatggctga ttgccggcgg attgattggt
    32941 ttgggtatga tcgtcccagg attgagccct tctaattttt tggtgtatat gggattgtat
    33001 aaagcgatgg ctgacggatt taaagaagta cgacttgaag tgattgtgcc gatcggaatt
    33061 ggtgggattc tttgtgttct tggattgtca aaaatcatgg attacatttt ctcaaaggca
    33121 tatagcaagc tattccattt cattttaggt gtagtttttg cttcaacgat tatgatcatt
    33181 cctaccgatt acgcgggatt gggagttgct ggggtactag cttgtcctgt tctttttata
    33241 gccggtacag cactaggttg gtggatgagc cgtttggagg aacaatataa gtaaagatag
    33301 attgataata aaaacagcac acgggtgatt caaacaaaaa ggttggcatc ttttttgtaa
    33361 aatcattcgt gtgtttttct ataaatttta taaaaacaag ttgtttttaa tcttggaaca
    33421 cgctagactt aaacacgtga ttatttttga aagttggcgg aaaatggaga aaaagaaaat
    33481 gaatggactt acacagcaag aggtagttca gaaaatggct tctggccagc aaaatgacta
    33541 ccaggaagat gcatcaaaaa gtacaaaaca aatattcagc gataatatat tgacgttatt
    33601 caattttctg aactttggta ttgggatttg tctgttattt gtaggtgcgt attccaacat
    33661 ggcgtattta gcaattattg tcgtcaatat cgttattgga atttatcaag aaatacatgc
    33721 aagaaatctt gtacggaaat tatcgattgt ttcccaatca gaagtactag tgatccggga
    33781 cggtaaagaa caatcgattt ctactaaaga gctggtatta ggagatttgg taaaaatcgg
    33841 agcaggagaa cagataccag ccgatttaca ggttatatct ggacgggcag aagcaaatga
    33901 agctcttttg acaggcgaat ctgatttgat tgtcaaagaa actggagctg aattgctttc
    33961 tggaagcttt ttgacaagcg gttctgtcat ggctgaagtt atccgagtag gtgcagataa
    34021 ttatgctgtc cgcttgacta gcgaggcaaa gactcacaaa gctattcgtt ctgaacttgt
    34081 agattcgatt cgcaaagtat ccaaattcac tagtttcgtg attattcctt tggggatcat
    34141 actatttttg gaagcactgt tcatccgcga tgcttctatc aaaatttctg ttattgcatc
    34201 tgcagcagct ttgttaggca tgcttccaaa gggtttggta ttgctaataa gtattgcatt
    34261 aacgacaggg gtaaccaaac tggcaaaaaa acgaatcctt gttcaagaca tgtattcaat
    34321 tgaaacgctg gcccatgtcg atacattatg cttggataaa acagggacca ttactgaagg
    34381 gaaaatgagt atccagcggg tagaagcact acatccgctg tacgagaaag ccatcccaga
    34441 aattatgggg acgtatctgg cagaaagcag tgataacaac atcactatgc gggctatgag
    34501 agattatttt gagctttcta atcggtatga tgtgacaaac aaagtcgcat tttcttctga
    34561 tcgcaaatgg ggcgcgatgg aatttccaga actgggagtc gtgtacgtag gagcgcctga
    34621 acgtttggtg gaagaagatc ggcttccgga cagtctaaaa acagcccaag cgaatggcta
    34681 tcgcgtactt atgttgggga tcgctccaaa tcagcaattg aacgaagaaa aaccagcatt
    34741 tgttgagccg gttgctctgt ttgaaatcga tgatccaatc cgaaaaaacg ctcaagaaac
    34801 actagcttat cttcatgagg aaggtgtgga tctgaaagtg atttctggag acaatccttt
    34861 tactgtctcc aatatcgcta gacgtgcagg attaccgaat tatgatgcgt atgtcgatct
    34921 ttctcaaatt actgaagaaa tggaagtgcg agaagctgct catcgctata cggtttttgg
    34981 acgagtgagt ccgcagcaaa agaaattgct ggtaaatgaa ttgaaagaaa gcggcagaac
    35041 ggttgcaatg acaggcgacg gtgtgaatga tgttttggcg ttaagagaag cagattgcag
    35101 cattgctatg gcagaaggtg atggagcaac acgtcagatt gcgaatctgg tattgttgga
    35161 ctctgatttt actacattgc cagaagtcct gtttgaagga cgccgagtgg tcaacaatgt
    35221 gacgaaagtc tcaggcatct tttttatcaa aacgatttat tcatttattt tatcgattat
    35281 atgtgccgtt acagcaattg gatttccgtt tatccctatc caaatcacgc tgattgattt
    35341 agcgattgaa gggtatcctt ccttcttttt atcttttgaa caagataaaa gaaaaatcac
    35401 ttaccgttat ttgcctacag cacttattaa tgctttacca aatgccttgc ttgtagtagt
    35461 gaatatcatt gcggtgtatc tacttggaaa aacattcgca tggggaaatg ctgaaactac
    35521 tactttgatg tattacttgc tgattgggat cagttgcatg gcagttgtaa aagcttgtta
    35581 tcccttcaac ccattgcgca tcttcctagc agtaacgacg atcgtaggga tatatgtagc
    35641 tgcaatgctg ttccatggaa ttttggaagt aaacttaggg ttgggagaga gcgtaggata
    35701 cttctttgta ttcatgctcg taaatattgt tcttcgagta ttgtactgga aggctgatat
    35761 tcaaaatcag ttactgaaaa gagtagcaaa ttgatgctta atgagataga aatgtgttat
    35821 acttgaaaaa gcaatgaaat atgatacaat caaacatgta taattgtgtc ctttaaaatc
    35881 gcactgattt cagttagtgc gattttttac cggttattct cctgaaatat cttctgttaa
    35941 acccaaaaga tatcaataga gcagggggtg aaaaaatggc tcaacggatt cctcaagagg
    36001 ttatcgaaac agtacgcagt caaacgaata tcgttgaggt gattggacaa tatgtccagt
    36061 tgaaaaagtc tggtaaaaat tacttggggc tgtgtccttt tcatgaagaa cgtacaccgt
    36121 ctttttctgt tgcagaagac aagcagattt ttcattgctt tggttgtggt aaaggcggaa
    36181 acgtgtttac ttttcttcaa gaactagaag gtctaagttt tccagaagca gtggtaaaag
    36241 tggcagactt cgaacagata ccgttagaag atcaatggcg tcagcgtact atagctgtcc
    36301 aaaatcctga atctgctacg gggaaactga ttgctgctca tgaaaaagca gcggaaatct
    36361 atcatcacat gctattgcat acaaaagctg gacagccagc tttagaatat ttgcaaagtc
    36421 gtgggttgtc tttagaatta attgaagaat tcaacatagg ttttgcacct aatgagcgtt
    36481 cttttcttca gcaagtattc aagaatgaat caatttcaaa tgaattgtta gaacgctctg
    36541 gattgtttgt cacgcatgat gatggccgta tgtctgatcg tttttatcaa agagtgatgt
    36601 ttccacttcg taattctcaa ggccagacga tcggtttttc aggacgctgg cttgcacctg
    36661 aaaaagggca ggaaaaagat cagcccaaat acttgaatag tccagaaaca gaactgttca
    36721 ataaaagaca agttttattt aatcttgata aagcaagaag cgatatccgg aaaaacggag
    36781 aaattttgtt gttcgaaggg tttatggatg tgattgctgc atggcaggct ggtatcaaaa
    36841 ctggattagc ttctatgggg acaagtctaa cagctcaaca gatccaacaa atggaaaagc
    36901 tgacgaaaga attggtcttt tgctatgacg gagacaacgc aggttttgaa gcaaccaatc
    36961 gagggattga attgcttcgg caaaacagtc gattagcact ttctgtcgta gtcgttccag
    37021 aaaagcttga tcctgatgaa tatctccgta agtatggaga agcatctttc caagaattag
    37081 tggctcatgg gcgcgaaaca gtctttactt ttaaatcacg ttatttaaaa caagggaaaa
    37141 atttagataa tgaaaaagac aagatcgaat acctcgaaga attactagtt gaacttagcc
    37201 gagttgtttc accaatcgaa caagatatgt atctatctca actgtcaaca gagtttcaga
    37261 tcggcagaga gacgatacaa aaacaactgc gcgatcttcg aaggacaaat cagcaaaatc
    37321 gtcaagaacc tcaggaaagt caacacactc aggttacgag acaagaaact gcacggaaaa
    37381 agagaccttt gacgcaagta gaaaaggcag agcagattct attatatcgt gcatttaaag
    37441 aagtttctgt ccgtaatatt ttaaaagaac gagaatttca gtttattcat gatgcatatg
    37501 cagaagttta ttttttattc gatgcatatg tctcacaaca ttatgaattc aaccttgcag
    37561 agtttttaga ctttttgcaa gatgaaaatt taaggcggtt ggtggtggaa atcgaatatt
    37621 taccggtggc agaagaaagt tcgccacgag aaatccaaga cttgctagat gtgatcagca
    37681 aatctggctt agctgatgaa ataacattaa aaaaacaaat gcagcaagaa gccagacgaa
    37741 ctggaaacaa acagcttgag cttgaattga cgattgaaat catcaattta acgaaacagt
    37801 taaaacaagc caaatagcta ctcaaggggg gccttctttt atggcaaatg gaacagataa
    37861 aaaaacgtat gaagcagcag tagcagcttt catcaaagaa aacaaaccca aacgacaagt
    37921 tgtatatgat gatttatcca atcagcttgc tacaccattc actttgaatg cagatgaaat
    37981 ggacaaattg atccaaaaga ttgaagacgc aggtatcagt gtggtggatg aaaatggtga
    38041 tccatcaatt cacagcttga agagtgctga gaaaaaagct gaacaagcaa aaacagaaga
    38101 tctttctgcg ccaaccggtg taaaaatcaa tgacccggtt cgtatgtatc tgaaagaaat
    38161 tggccgtgtc tcccttttaa ctgcggaaga agaagtagcg ttagcattga aaatcgaaga
    38221 aggcgaccaa gaagcgaaac agcgtctggc agaagcaaac cttcgtttag tagtaagtat
    38281 cgctaaacgt tatgtaggac gaggcatgca gttccttgac ttgatccaag aaggaaacat
    38341 gggactgatg aaggcagttg aaaaatttga ctaccgcaaa ggatttaagt tttcaaccta
    38401 tgctacatgg tggattcgtc aagccatcac tcgagcaatc gctgaccaag cacgtacgat
    38461 ccgtattcca gttcatatgg ttgaaacaat taataaattg atacgtatcc aacgtcaatt
    38521 gctgcaagac cttggaagag aacctacgcc agaagaaatc ggtgcggaaa tggatcttcc
    38581 aacagaaaaa gtccgagaaa tcttgaaaat cgcgcaagaa cctgtttccc ttgaaacgcc
    38641 aatcggtgaa gaagatgact ctcacttagg tgatttcata gaagaccagg aagcaacaag
    38701 tccagcagaa cacgcagctt atgagttact aaaagaacaa ttggaagatg tactagatac
    38761 attgactgat cgggaagaga atgtccttcg cttacgtttt ggtttagatg atggccggac
    38821 gagaacattg gaagaagtag ggaaagtatt tggtgttact cgggaacgta ttcgtcagat
    38881 cgaggctaaa gcattaagaa aattgcgcca tccttctcgt tcaaaacaat taaaagattt
    38941 cttagaataa gcgtggacta ttgaccagaa gagaaatcag taaaactgtt tggtttattt
    39001 taaaagaaaa aaagcttgag actacgcagt ctcaagcttt tttttctata ggaaggaaat
    39061 tcattcatta tttt
//
LOCUS       DAFEEZ010000020        37176 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000020
VERSION     DAFEEZ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.020"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            476..1339
                     /locus_tag="LP245_001131"
     CDS             476..1339
                     /locus_tag="LP245_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL1519061.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="LP245_001132"
     CDS             complement(1468..3090)
                     /locus_tag="LP245_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1519062.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="LP245_001133"
     CDS             3339..3860
                     /locus_tag="LP245_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBL1519063.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="LP245_001134"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="LP245_001134"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBL1519064.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="LP245_001135"
     CDS             5941..6759
                     /locus_tag="LP245_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBL1519065.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="LP245_001136"
     CDS             complement(6862..7059)
                     /locus_tag="LP245_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519066.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="LP245_001137"
     CDS             7228..7806
                     /locus_tag="LP245_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBL1519067.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="LP245_001138"
     CDS             7901..8038
                     /locus_tag="LP245_001138"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519068.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8850..9353)
                     /locus_tag="LP245_001139"
     CDS             complement(8850..9353)
                     /locus_tag="LP245_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL1519069.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9712..10737
                     /locus_tag="LP245_001140"
     CDS             9712..10737
                     /locus_tag="LP245_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL1519070.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11084..11962
                     /locus_tag="LP245_001141"
     CDS             11084..11962
                     /locus_tag="LP245_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HBL1519071.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12438..12554
                     /locus_tag="LP245_001142"
     CDS             12438..12554
                     /locus_tag="LP245_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBL1519072.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13482..13820
                     /locus_tag="LP245_001143"
     CDS             13482..13820
                     /locus_tag="LP245_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519073.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13914..14144
                     /locus_tag="LP245_001144"
     CDS             13914..14144
                     /locus_tag="LP245_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519074.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14544..14915
                     /locus_tag="LP245_001145"
     CDS             14544..14915
                     /locus_tag="LP245_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBL1519075.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15189..15881)
                     /locus_tag="LP245_001146"
     CDS             complement(15189..15881)
                     /locus_tag="LP245_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL1519076.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15884..16669)
                     /locus_tag="LP245_001147"
     CDS             complement(15884..16669)
                     /locus_tag="LP245_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL1519077.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16906..18306
                     /gene="lacG"
                     /locus_tag="LP245_001148"
     CDS             16906..18306
                     /gene="lacG"
                     /locus_tag="LP245_001148"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBL1519078.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18331..18648
                     /locus_tag="LP245_001149"
     CDS             18331..18648
                     /locus_tag="LP245_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL1519079.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18661..20334
                     /locus_tag="LP245_001150"
     CDS             18661..20334
                     /locus_tag="LP245_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBL1519080.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20348..21979
                     /locus_tag="LP245_001151"
     CDS             20348..21979
                     /locus_tag="LP245_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBL1519081.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            22851..24041
                     /locus_tag="LP245_001152"
     CDS             22851..24041
                     /locus_tag="LP245_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HBL1519082.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            24175..26364
                     /locus_tag="LP245_001153"
     CDS             24175..26364
                     /locus_tag="LP245_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1519083.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            26361..28154
                     /locus_tag="LP245_001154"
     CDS             26361..28154
                     /locus_tag="LP245_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBL1519084.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            28354..28668
                     /locus_tag="LP245_001155"
     CDS             28354..28668
                     /locus_tag="LP245_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1519085.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            28689..29066
                     /locus_tag="LP245_001156"
     CDS             28689..29066
                     /locus_tag="LP245_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1519086.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            29076..29849
                     /locus_tag="LP245_001157"
     CDS             29076..29849
                     /locus_tag="LP245_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519087.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            29871..31274
                     /locus_tag="LP245_001158"
     CDS             29871..31274
                     /locus_tag="LP245_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL1519088.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            31456..32640
                     /locus_tag="LP245_001159"
     CDS             31456..32640
                     /locus_tag="LP245_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL1519089.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            32637..32927
                     /locus_tag="LP245_001160"
     CDS             32637..32927
                     /locus_tag="LP245_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519090.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            32924..33145
                     /locus_tag="LP245_001161"
     CDS             32924..33145
                     /locus_tag="LP245_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519091.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            33187..33966
                     /locus_tag="LP245_001162"
     CDS             33187..33966
                     /locus_tag="LP245_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HBL1519092.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            34033..34527
                     /locus_tag="LP245_001163"
     CDS             34033..34527
                     /locus_tag="LP245_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL1519093.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            34583..35221
                     /locus_tag="LP245_001164"
     CDS             34583..35221
                     /locus_tag="LP245_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519094.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            35293..35688
                     /locus_tag="LP245_001165"
     CDS             35293..35688
                     /locus_tag="LP245_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1519095.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            35672..>37176
                     /locus_tag="LP245_001166"
     CDS             35672..>37176
                     /locus_tag="LP245_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1519096.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKA"
BASE COUNT        12162 a         6102 c         7302 g        11610 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacgctt ttgttatttt atacttaaaa ataacgacac agaaaatacc gtgtctcaga
     8401 tttctctact acttctaaaa actactgttt ttttcctttg aaatgccttc aaaaagtagg
     8461 atcaggcaga atatactggc agaatcaagg agaagggagc ctaaataagg agaaaaacca
     8521 tagaaaatat aaagtaatta cttataaaac aagcttttta tagaaaaata atatacctga
     8581 gtagggtata aattaagacg gaattccttt ctagattgag atattgacta ggaagaatgt
     8641 taagatttta agcctttaag ctaaaaaaaa accctttttg ttaaataagg ggaatatagc
     8701 ctgtcagttt caaactgcaa gtcgtcctgc tgcaataata tagtagatta gagatgaaaa
     8761 tagatttttt taaaccaatg actgaataaa aagaccgtca tagatacaca ttggaatgtg
     8821 tctattacgg tcttttttta cgaacgattt tattgaagac ggacagttcg ggtcaaaaat
     8881 aaaaaagcta cgatcagaaa taagaataaa atgtatccca aaataatggc tagacggtct
     8941 aacttatttg tcgatagatg tttgtttaga agttgatagg cccataaacc tatcagtcct
     9001 cctgttgtat tagttatcaa atcagtgatg tccgctacgc caataccgaa taggaattga
     9061 atcaattctg ccaagaagct tacaaggaaa ataatcccta attttttaga aaaagaaagt
     9121 ctcttgaaat tgacattcaa aagcacccca aaaggaaaaa agacaatcaa gttataagtg
     9181 gtctcacgta ataccgtcgt attttcaaaa gaaaaagtag aaaaagggac gagattgaca
     9241 ttgctgtaag aataagtgag aaattgtgga agattaaatg atagcttgaa taaaatcaac
     9301 cataatagaa agaataaata aatccctaat aaaaattttg atacataccg catagacatc
     9361 tcctccattt aaaaagtata ccatcgaaaa ccgctgaaaa atcataaaaa agtatgaagt
     9421 ttaaggacca acgtagttat cgtacgaaaa ttagaagctt ttttttgttg ggaatccggt
     9481 ttctttaaca aagctaagat agcgagttgc ttggaaaagt tgctatcttt tttctgtcaa
     9541 aacgactcgg aatgttcgtt ttttgttcta atttctccaa gttgtttact ttttgatact
     9601 aagtttatga aaaatcaaga aatagttgtt atactaggta atgctgacaa acgggattgg
     9661 catttcatct tggttcagct ttttttccaa ttactaggaa ggagggatag attgttcaag
     9721 acttattttc gtttcaataa aatacaagat aatccttttc gtatcatgaa tctgatgcta
     9781 cttatcttta ttgtattatg gttaggttac ataaatcatg attttttgat ttcaagtttt
     9841 tcatcattag ggatctttac ttttttctat tatcaaaaca taccgatgaa atatttgctg
     9901 aaacgtatgt ttctgatcgg ttgcggactg ttggttgctt tcgttttggg gatcttatcg
     9961 acttatgttt tatggcttga accatttgcc gtagctttgg ttgctttttc cagcagattc
    10021 gtgttgcgat tattccatat ttctaaacca ggtggcttgt tttttgcgat gctttctgcc
    10081 atgggaacga gcatgcagct gccaatcgct caattaccga tcgtctcact ttattttttt
    10141 atgggtgtcg tttttgccct gattgcggca gtgattacaa aattactgga ttcacggcct
    10201 gagcagacaa ttgaaaaagc aactttaaaa gaaagatttc acgaagagcc tttagtgatc
    10261 attgattctg ttttctacag cgctgcctta tttctttccg tttatgtcag tcacggcttg
    10321 aatctgcata atccttattg gttgaccttg tcatgtgcat cgattttgct agcagaaaac
    10381 ttggatgcga tgaagcatcg acaagtccaa tatctgattg gatcgatggg tgggttatgt
    10441 gtgtcggcat tcttgtcatt tgtgccgttt acgcagttgc agaccatttt tctgatcact
    10501 tttctatatg gaatcgcaca atttctagtt gctagaaatt atgcagttgc taatattttt
    10561 cttaatccga tggcgttgat gctatctaca cttattcgtg gagcatactt gatttctttg
    10621 atcgaatatc gttttttagg gatcgtcata ggaagtttca tcggtttagg tgttgcgtgg
    10681 gtaatgacgg ttggtttgca acattattta acggttgttc gtcaaaaatt agaatagaag
    10741 gacaaatata tgtgccaaaa gaggttatga caagattttt gtcacaacct ctaattcaag
    10801 gtgttcaaaa gccagattct cagcattaag tcaaattcac acaaaaatgt ggaaaggaac
    10861 tttcaaaaaa attttatatt tattctatca aaaaatttta tatttattct atcaaaaaat
    10921 tttgtttatg atggtaactg aataaacttt cctgagatgg tcaatgcttt ccttgaaagt
    10981 cttacagata ttctttcttc atagaaagtt taagttttat agttagtgta caataaaagt
    11041 atgtttatac catatggtgt ccggataatc agtcatttaa acaatgaggt tcaaagatat
    11101 gaaaagggga aatttgatga agaaaataag caatgaaatc caaattctgg cagaaacttt
    11161 aactcttccc aaagtcgtta tagagcaaat gattgtacaa gcaaaaaaca tccttgatga
    11221 ggtgtttgag caatatagtc atgaactaat ggatcctaat aaagcaaagg cgactgcaaa
    11281 gaaaatagac aaagtctatg aagaggaacc ttttgcagca ttagctattt atctatatgc
    11341 agcttctcaa agttggaaaa aaatttatca accattgaag attccaagaa ctatctattt
    11401 ggcaacaatg aatgctttta ctagatttat tcatgaacat ttccaagtaa caggaagcta
    11461 tcgctttgac cgtggttttt ggatttggca ttacactagt ggcttgatct ttcggattgg
    11521 tgaattggag tacgaaatga catattttcc gaaagggtac acggatctaa gattagaagg
    11581 aaagcagtgc ctttctcttc atattccttc cgatgcagat ttatctcaga ataagataag
    11641 agatagttac gaaagtgcca ttcgtttttt tgaactttat tttcctgatt accattacca
    11701 agtgatgtac acagatactt ggttactatc acccaatctt actaaatggt tgaaaaaaga
    11761 gtcaaaaatc tgtctttttg cagccgatta tcgattatta tcagttgatg aacaggacga
    11821 tagtggagtc ccttggatct ttggacgagt agatgcccaa atacatgatt atccagaaag
    11881 tacgagttta cagcgacaag caaaagagca attgcttgca ggcgagcaca ttggctctgg
    11941 cttaggtatt cttacttcat aagtttagta cttcgaaata gtttaaaaga gcgtgagaca
    12001 aaagtaaaga acacttttgt ctcacgctct aaacacgtat aaacggcgga agcagaagca
    12061 actccttcgg aaataagctg aaattcacaa aaatttgaaa agcaattttc gtgaatttct
    12121 tcttatttct tggagttaaa cgcttctgtc ccagcctctt ttttagtgtt ctatcgaaca
    12181 cacagtacgt tcaataggta aactagctat aacaatagat attaaagtta acggacaaga
    12241 gggccttttt taggtagcta aaacgtaata atgaaaattt atttccagag ataggagtca
    12301 atcagctagt ctgatcgact gttttaacaa gttgactttc attttaactt ttgataccat
    12361 ttaaaacaca aatcgtaatt gtttcgattt gtgtttttta gcatgactac aatcaaagaa
    12421 gaaagtgggt cgtccatatg gaaaaaacag atatctcaag tgcataccgc cgcttgaaaa
    12481 gcccaaatat caaaacacga aaacgtgcgc tgaagatcat caaagatgtg aaacggaata
    12541 gtgggaaaag gtaagaagaa ggaaacttaa ttaaaaaaat agccgaaaaa cgtttttcgg
    12601 ctattttcaa taatcggttt ttgtgtaagg tttccgaaag aactgctgtt gattttccat
    12661 ttttaacata tgataaattg gtagaatctt tcttttcaaa ttgataccat tccctaattc
    12721 cagttatata gttaactaca gaaccacaaa gcacgtacgt ttataaaagt attatctgta
    12781 gttatttttc aattcccttt caacctctta ttttgaccag tagtattgat cactttacct
    12841 tttaacacct ttgttcgttt ttgaaacatt tttagtcaag aatggaaacg taactacata
    12901 atcaaaggtt ttgcgaaata tttcatgaaa tatttcatgt agaagcgagc aatacggttg
    12961 caaataacca ttatcgttta ataagcagtt acgaaagctc ccaatatctc taacgttcag
    13021 ctcactccat ttcttttctt caaaaaaatc agtgattcgt atctctttct atttgtcgaa
    13081 aaagttaact ttaaaaagta acgccgaaaa aatatgcaaa aaaataaaaa agcagttact
    13141 attgctagaa taacatcaag gaataataag ttttggtttt cagataatag tcgataagtt
    13201 gtgtattgga attttagata cagtaataaa gtatttttca tgaaattttg tgagaatcac
    13261 tattacaagt atctttaata aaattaatgg ttaaggagga acttaaagta gaatgtaaat
    13321 gaatagttgt agtcagtcga ttgtgatact agactcaaag ttgcaggaat aagtttttca
    13381 atttgtgatt ggaagataaa aaatgaaaaa gaagggcttt tttttatact ttgttgattg
    13441 tagtgtttat tttccctctg tttagccaag taacattttc tatgactcaa ccagtttcaa
    13501 gtgaggaaca tgataacctt tttcgtgcta cagaagagtt taagaaatat caggaaaata
    13561 ttgttccgga gactccatta gctagtgagc caattactga tattgatgga aaccaaatag
    13621 gatggtatat acagtacgaa gttatggtgg taaataatga ctcaatagta aaaaatacag
    13681 taggcttaga gctaacaccg attgaaaagg tgagttcatt gttaacgtat atttatactg
    13741 atgaaagtga cgagactgag atcattttaa cggattactc aaaaattgct actgataaaa
    13801 agtatatatt gtggatgtag acactagtga aatactttat gatatagaaa ttgatgaaaa
    13861 tttactagat gtagcacaag aaatcgatca tcaaaagcag gaagctattc gatatgctgg
    13921 tagaaaaggg aaaagaaaat atttattacg tgaatgtagc aaaagttaga gaagatgaaa
    13981 atgagtggaa agaattcaag agtcgctact caattaactc gactccgaca tttacagttt
    14041 acagagaagg atcgatagaa aaaactgttt tttggactaa agaaagtgga atgtctttag
    14101 ctgaagtaga agagtttttg gattatgtta gtatgcaaca gtaagggagt tcttattatg
    14161 aaaaattttg acacatatta tgttattgtt ttttcgatat ctttgctgtt aatattacta
    14221 actttaatgc agtataaaga gtatccagag tattttattt taacttttgt atatttagta
    14281 agtagctaca cacttctata taaattcaga agttcttcta gagtttctaa agtttgtttc
    14341 ttaattagct tattgattct ataatatttt tgatttatat aggaaattaa aaatattata
    14401 gaatcaacac tcagagaacg ggttggtttt taatagattt aataagtact gataatgaaa
    14461 tttctcctgg ttgggaaaac gaagttggtt accctgtaga agaatttttt caagattact
    14521 ttgcggagta tgccgatagg ataatgagag attacgtaac agataaaact caagaagtca
    14581 tcaatcaatc ccagtcatta aatgaattat ctgataaggc gaaagaagaa gcagttgcca
    14641 ttatttcttc agggattagt gactatattg atatgagtgg tgaaatcaat tatggcgata
    14701 aagacaaaat tgtacgcatg ataaaagctt ttatcaaaac ttttgatgtg aaggcagatc
    14761 ttaagtttaa tgatacttac ctagtaggaa aattaattaa tatccttggg acagagaaag
    14821 atacggaaac gtttatttcc tctttgtcta tgttgtttac agataagcat ttttcaactc
    14881 agcttggtgg agaggaacta gtggaaatct tttaaccatt acgcccagca ttaataaaag
    14941 tatatcaaaa aagtactcct gatgattttt aagattggtt tgagaaataa tgtgaaaaca
    15001 ctatttttaa tgttaattat agatagagat gaacgcgtca tatggttaaa agaatgaaaa
    15061 agtcaaagat acactgctat atttcactaa ggatatagca gtgtatcttt catgtcgttt
    15121 cactggcagt tttttataaa aggaggtgtg catttcagtt gcttttcttt ggtagttagt
    15181 tgaatcgttt aagaattaac ggatgtggca gacaggtgct ctgtccaaaa accagtaaaa
    15241 tctttgatgg ttccatcttt atttagctgt gcctgttcaa atactgtttt gtttttaccg
    15301 aatggatcaa ttgcaataat tgttccgatc cccgcacgtt tggcagcaag taatcctgag
    15361 taagcatctt cgataacaag acaatcagcc ggagctaagc tcagtttgtc tgccgcttta
    15421 agaaaaatat ccggttgcgg tttcccaggg aaagagccgt cgtcatagac aatcttgtcc
    15481 cagtcaaacc agcgggctaa atcgaaaata tcaaaataaa aagcaacatt ctctttgaca
    15541 gtagccgtgg caatcgttaa tggaatctgt tggtcagtca gctggtcaag agtcgcttca
    15601 agcccttttg tcaactgaag ctcgttttca ttttgcaagc aaagcatacg ataatagctt
    15661 tctttttctt ctgacaatac ggcgatctca gaggcggtca aatgctctga aatgaaatgt
    15721 ttcaaaatct ccgtattcgt ccgaccatga atatttttta aaatatcctc gtctgataaa
    15781 ccatcttttg tatgatcatg tatcatatgc agccaagcag cttcatgcag atgagagtcc
    15841 aaaaacattg ttccgttgaa atcaaatata atccctttca tagttacgct cctatagtgg
    15901 tattttcggt tgaatcagca atttgcagat cgacatattg tgcatagtgc tcttgaacct
    15961 cccgcgagat ctggcgatcc gtaatgagca gatcgaaatc atgcaaatta taaaacacat
    16021 aaaaatcatc tcgattgaat tttttattat caacgagtag atatttctta cgggaattat
    16081 ttagagcgat ctgctgtgct tctccttctt cggtactgta agtagagatc gcttcgttgt
    16141 gaacgccatt tgaactgata aatgcttttg taaactttag tcttcttaaa ttgtcgttgg
    16201 tgatcggtcc gacaaatgcg ccggtatttt tccggaaatc accgccaatc agtagaattt
    16261 ctggtccatc tgcttgagca agaatatcaa aaactggata attatttgta atgatccgaa
    16321 ttttcttgtt cagtaaatgc gtcgccaata gttcgattgt tgtacctggt cctaagaaaa
    16381 tcgtttctcc ctcgtgaatc aaggaggctg ctgtggcagc aatttctttt ttttcttgaa
    16441 tctgcagagt ggctttttca gtgtgagaaa gttcttgatc taaagtgtag gaaagacttt
    16501 gagcccctcc atggacacgc agcagcttgc ccgatttttc taattcatct aaatctctgc
    16561 gaacggtcat atcagaaaca tctaattgat tgatgatttc attaacggta aggattcctt
    16621 ttttattgac catttctacg atagtaagca atctttcttt tttcaacatt gtcttcacct
    16681 ctaatttaag gataatctat catataaacg gacaacagtc aatctaattc gaacaaaagt
    16741 aaacatttag ggtggttttt atgtttgtta caatagattt tattgctgtt ttctggtttt
    16801 tatgattatt tgtgtttgtt tttgttgaca aatgttttgg atgcgtttac aatgcaatca
    16861 gttagaaaga gcgaaaactg attatagatt tgaggagaga tgtacatgct taaattacca
    16921 gaagatttta tttttggcgg agccacagca gcctatcagg ttgaaggagc cactaaggaa
    16981 ggtggcaaag gcgctgttgc ttgggatgac tttttagagg aacaagggcg attcagtccc
    17041 gatccggcaa gtgattttta tcatcaatat gcaaaggaca ttgaattgtg tgaacgtttt
    17101 ggtgtaaatg gtctaagatt atccattgct tggagccgca tttttcctga tggagctggg
    17161 aaaccaaatc cagaaggaat cgctttttat catcgtgtgt tcgaagaatg taagaaaaga
    17221 aacgtaacgc cgtttgtgac gttgcatcat tttgataccc ctaaacgttt gtttgaccat
    17281 ggagattttt tgaatcgaga aacaatagaa gcatttgttt cctatgccat tttttgtttt
    17341 catgaattca aagaagtcaa ggtgtggagt acctttaatg aaatctatcc agttgcaacc
    17401 aatcaatatt tgttaggtgt tttcccacca ggaatcaaat atgattttac aaagatcgtc
    17461 gcctgtcttc ataatatgat ggttgctcat gcccgtgtag tgaactattt caaagaaaac
    17521 gaacttccgg gtgaaattgg tgtagttcac tcattagaga cgaaatatgc ggcaacagac
    17581 gcgccggaag ataagcatgc tgccttttta gacgatgcat tgtcgatccg tttcttatta
    17641 gatgctacct atttaggcta ttattcaact gaaaccttga ctgctcttga tgagatatgt
    17701 gaagcaaatc aggccagcta tcattttcct gaagaagatt tcgttgaatt gaaaaaagca
    17761 tccacgcgta atgactactt agggatcaat cactaccaat gccattttgt caaagcttac
    17821 gatggagaaa atgcaatcca tcataacggt acgggtgaaa aagggacctc tgtttataaa
    17881 gtgaagggaa tcggagaacg tatttataaa gaaggaattc ctcgaactga ttgggactgg
    17941 ctgatttatc cagaaggtct atatgacttg ttgctgcgaa ttaaaagcga ttacccacat
    18001 tacaacaaaa tctatatcac tgagaacggg atggggtata aagatcagtt tgaagatggc
    18061 attattatgg atcagccgag aatcgactat ttgagagtct atttggaatc cttaagcaag
    18121 gcgataacag ccggggtaaa tgtgaagggg tattttttgt ggtcgcttat ggatcttttc
    18181 tcatggacaa atgggtataa caaaaggtat ggcttgtttt atgttgattt tgaaacccag
    18241 aagcgttacc caaaagaatc agcttactgg tacaagttgg tcagtgaaac caaaacgatt
    18301 atttaataag tgataatgga ggaagaaaag atgaataaag aggaattaca aatgcttggt
    18361 tttgagatcg ttgcatattc aggcgacgct cgcagtacat tattgaaatt attgaaagaa
    18421 gtaagacaag gaaactttga acatgttgat tcggcgttga aagaagccga cgaaaattta
    18481 acccttgcac ataattcgca aacaaaaatt ttagcggaag aagcatctgg gaaagagatg
    18541 gagatgggat tcatttttat ccatgggcag gatcatttaa tgaccacttt attgctgaga
    18601 gatctgattc aagactttat tgtactgtac agacagaatc aaggatagga gaagaacgct
    18661 atggatggaa tcattaaaca aatcgaaaaa gggaaaccat tttttgaaaa aatctcacgt
    18721 aatagttatt taggagccgt tcgtgacgga tttttaacag cgatgccagc tattttattt
    18781 tcaagcattt tcattttgat tgctgcggtt cctgagattt ttggttacca atggcctgaa
    18841 tctgtctcca catggctatg gaaagtctat aattattcga tgggtgttgt agggttactc
    18901 gtttcagcaa ccactgctcg ctgcttggct gattcgatga atcgtcgctt accgaaaaac
    18961 aaagtaatca acaccacctc tgtgatgctg gcctctgtgg taagtttcct gttgttaagc
    19021 gtctctccga ttgaaggtgg attttcaacg gaatatatgg ggacaaaggg actactggct
    19081 tcctttgtcg ctgcattttt aacagttaat ttatataagt tttgtgtgct gaaagatatt
    19141 accattaaaa tgcctaaaga agttcctgga acgatttcgc aaaccttccg agatattttt
    19201 cctttctctt tttcagtatt tgcggccgtt ttaattgatt taggcattcg acaaatcttc
    19261 caaatctcat ttgcagaagc aatcattacg gtgctgcagc cgctatttac agcagctgac
    19321 gggtacttag gaatcgctat tatctgggga gcgatggcgc tgttttggtt tgtcggtgtt
    19381 catggaccgt cgatcgtgga gccggcaatt gcggcaatta tctatgccaa tgtggaaacc
    19441 aatctgcaat tgttcaattc cggtgaacaa gcttctaaag tactgacggt gggtttaggg
    19501 aattttgtag gaactatggg aggaactggg gcaacattgg ttgttccttt tatcttccta
    19561 ctctttgcta agtctaagca gttgaaggca gttgggaaag cttcctttat tccagtaagt
    19621 ttcgctgtca acgaaccatt gctatttgcg gcacccatga ttttgaaccc ttattttttt
    19681 attccatttt tgttaacacc tgttgtaaac gtttgcctgt tcaagttttt tgtcgatgta
    19741 ttgggcatga acagctttat gtacgttttg ccttgggcaa ctccagcacc gatcggtttg
    19801 gttctaggaa cgggcatggg tatcttagct tttgttctag cagcggttct aatcgtcgtt
    19861 gacttcctga tctatctacc attttgcaaa gcatacgatg ctgtcttagt agagaaagaa
    19921 gcacaaaaag cagaggtgat cgcaaccgag gaaggtgctt ctgccgatgt acgtgaggaa
    19981 gtacctgtgg cagcgagtca agttatcagc gatgcaaata aagaaatcaa tgtgttggta
    20041 ctttgtgctg gcgcagggac aagtgcgatg ttagctaatg ctttaaaaaa aggtgcatct
    20101 gaatcgaaag caccgatcag tgcaatggcg ggtgcttatg gttctcatta cgaaatgctg
    20161 caggattttg atatggtggt cttagcaccg caagtcaatt cttactatga tgatatcaaa
    20221 gaagacaccg atcgcttagg aatcaagctg gttgcgacaa aaggagcaga atatatcgga
    20281 ttaacgagag atcctgaaaa agctgttcag tttattctga accaatttca ataaaggagg
    20341 agccataatg aaaatgggaa tttggttgcg taaagctgtt ttatttgcag ctgtgttagg
    20401 ggctttgggg gctgtttcaa aaactgttga agcatctgcc agcgaattta ttcgcggagc
    20461 agatatttcg atcctgtcag atatggaaaa atctggtgca aaatattatg aagacgatat
    20521 ttcaaaagat gccttagaga ttttaaaaaa taatggtgtc aactatgttc gactgcgttt
    20581 gtggcaggat ccttataata gtaatggaga aagttatgga gcagggacaa atgatctgga
    20641 aacgacgatt gaccttgcaa aacgagcaaa aaatctggga cttaaggtgc tgctggattt
    20701 tcactacagt gatttttggg ttgatcctgg gaaacagaat cttcctaaag catggcaagg
    20761 tctgaccttt gaagaaatga atacggcatt gtacgactat acaaagaacg ttctgtcgga
    20821 aatgaagcag ctggacgttt atcctgatat ggttcagatc ggcaatgaac tgaatagcgg
    20881 aatgctctgg ccttatggca agtcttgggg agaaggcggg ggagaatttg atcgattggc
    20941 tgcttttttg aagtctggta tccaagctgt tcgagacact caacctaaaa caactccagt
    21001 aatgctccac ttagctgatg gtggcgatac aggagcattt acttggtggt ttgatgaaat
    21061 cacgagtcga ggtgtgtcat ttgatttaat tggagtgtcg tattatccgt attggcacgg
    21121 ttcaatgaat gaacttcaaa ccaatatgaa tgcgatcagc caacggtatg gtaaagaagt
    21181 gatcgtagtt gaaacagctt atgggcatac aacagcgaat gccgatacta tgccaaatgc
    21241 ttttggtgaa gccgaagcag ctgcgggggg atatgaacca acaccgacag gacaagcaga
    21301 gtatttgctg gatcttgccg atcggattca ggcagtaccg aataatcgcg gggcgggctt
    21361 cttctattgg gaacctcttt ggtacaacgg aaatgtgagt tgggcaacac aagcaggtat
    21421 gaattatctc agtgttcaat ccactatggg aaacgaatgg gacaaccaag cgatgtttga
    21481 ttttgctgga aacgccttgc caagcttgcg tgcgtttaaa caagcagggg cgcaaataaa
    21541 tctagttaaa aatgcaagtt tcgaaagcga tggaccaacg accagtcctt ccaattggca
    21601 aacctggttt caacaaggaa ccgctaaggg tacgatcaaa acggaagcgg gcactttttt
    21661 tggggactac aaactaactt tttggcagga tcaagcatac gaggcatcag cttatcaaaa
    21721 tgttagtggc ataagcaaag gaacttacac attgagtgcc tatgtaatgt ctgggggaga
    21781 gtttgatact aatcagttat atatcaaaaa ttatggtgga gcggaactaa atactgcggt
    21841 tgttaaaaca agtgaatgga caaaaattac aatcaaagac attccaatta caacaggtgt
    21901 ttgtgaaatt ggggtttata gcaaggcttc aggaaatgct tggacgaacg ttgattttgt
    21961 ttcattggtg aaacaataga ctgcggatcg tttcgattca agatcggagg ttcccttcag
    22021 ccacatcgtt agcgtagaag gcaggaatcg aacctgcacc tcgcctttgc caaaaataac
    22081 cagaaacgat ttccagtcat ttttaccaaa acgagtaaag caccagactt catctacact
    22141 ttgtattatg ctaaagagag ttcaacgatt tcgtaagaag caatgaaaaa attgcaaaaa
    22201 gttgtgcaga taacataaag tttgtttaag aaagggtaac cttagaattc cgtcgtgaat
    22261 atgatttgag cacttagatg gatagaaaaa agttctcgga aaacagttcg tttttcgaga
    22321 acttcttttt atgataagaa tgaaacaaat taacttatat tatagtctct tttggtaggg
    22381 aaccatctta tttttaatga aaatcaagca ttttagctat tgaagaatgt tgatttatag
    22441 ggattccccc tccatattat gttggctctt tattcccact ctgttttcaa cgtaaagtgt
    22501 ataaaacaga atgcgatact atcaagggag ttaaaacaat atacagaaca gtaaaacact
    22561 ataaataaaa ataaaagtgc aataaaagtg caatttttgc acctaatcat actctgttta
    22621 tatatgaaaa ctagattctg aatccaatat ttggttaacg agaggcgttc gaatttgaac
    22681 gtcttttata tattactttc aaataaatat gaggtagaat actatctatt ttctttttaa
    22741 cccaattgtt ataatggaga gtgtaaaata ttttgtgtaa atagaaaaaa ggaagtccct
    22801 tctgtagaat agagttacca caacacattc acagaagaga ggacttccct atgaacgatt
    22861 ttactacaga aattctaaag actctagcga acaaaggcga tttgaatgaa ttattccgtg
    22921 tccatttgga gaaagcagtc aatacgcttc tcaaaacgga gttaacggct ttcctagatt
    22981 acgaaaagta tgatcgcatt ggttttaaca cgggtaattc tcgtaacggc tcctatgacc
    23041 gtacggtcaa gaccgagtat ggggaacttc atctccagat tccgcgcgac cgcaatggtg
    23101 agttcaagca acagactgtt cctgcttata gacggacgaa tgacacgtta gaggagaccg
    23161 tcattcacct cttccgaaaa ggtattacca tgtcggaaat cgcagacttg attgagaaaa
    23221 tgtatgggca ttactacacg ccccaaacca tgtccaatat aacaaaatca tttacagaag
    23281 aggtaacggc gtttaatggg cgggagcttc atgaccgtta tgctgctatt tatatggacg
    23341 caacgtatat tccgttaaag cggaaaaccg tcgccaagga agctattcat atcgcagttg
    23401 gcattcgccc ggacggatca aaggaagtat tgagctatgc gattgcaccg actgaatcca
    23461 tcacgatttg ggaggaaatt ttattggacc ttcaagagcg cggtttgaaa aatgtcctcc
    23521 tgttcatcac ggatggctta aaggggatgg taggagcgat tagtcggttc tatcccaaag
    23581 ctcgttttca acattgttgt gtacacgttt cccgtaatat cagtcataaa gtgcgtgtcg
    23641 atgatcgtaa ggaagtctgt gatgatttta aaatggtgta tcaagcctca tctaaagagg
    23701 tggcgttgga agcacgtggt acttttgcgg aaaaatggaa aaccagctat ccaaaagtgg
    23761 ttgaatcgat tctttcgaac gatcacttgc tcactttcta tgatttcccc ttggccatac
    23821 gcaagagtat ttattctacg aacttgattg aatcctttaa taaacaaatc aagaaataca
    23881 gccaccgcaa ggaacagttc caaaatgaag agtcgatgga acgtttctta gtctcgtctt
    23941 ttgatactta caaccaaaaa ttcctaggtc gcagtcataa aggtttccaa caggccgaag
    24001 gcgagctcga acaaatgcta agccaactga ttgagaatta gaaacaatct gcagtaggga
    24061 agaatcattt acacaaaatt attgacgctc ccttataatg agaactttta ctaacataat
    24121 ttatgataaa cttactatat aatcatatta attaaatagt taggagatct gcttatgttt
    24181 atatctactc ttcaaattcg aaattttaga aattatgaat ccgaaatctt tcgattcgat
    24241 aatgagacaa atactattat aggtgagaat gattcaggga aaaccaatgc tcttactgca
    24301 ttgagaatct tattagatga tagttattac tatagtagta aaacactaaa agaatcagat
    24361 ttttttcatg gaattcaaaa tgggtggcaa gggcattgga ttattatctc tgcgacattt
    24421 gaaggaatca gcgaagaaga atttgacaat gagatttgtg cttccatttc tttaaattct
    24481 gaaagtcaaa caatcttaga agaattgatt tcaaatgcag ataaaggtgt aggtagtatt
    24541 tctctattta ttagacctaa caaagctatt agaaagcaat tatttgatat ttccactgaa
    24601 ttagactctc atcaatttaa cgaatttaga aattctattc gtctatccga ctatgaattt
    24661 tactacacat ctaaatcaaa tctaaatttc tgtatcaatg aaaattatga taaattggta
    24721 ggaagactca atgacaatat agctagtaat cctgaagaag acgatgaagc tctgttgggc
    24781 tcaagaattg acatgtcaga tattttcaag catatttcgg ttgtttatgt tgacgctctt
    24841 cgagatgttc ttagagaaat gaaaaacaat cgaaacccag tcaaaagaat catggaaaca
    24901 attgaatcaa aaatatcatc agataatgtt gagtcattaa aaacaattat acagcaatta
    24961 aatgagacta ttaccagtgt tcctgaaatt aggaaaattg gcgaaaatat taatcggcaa
    25021 ctaaatagca taattggttc agtgtattct cctaatcttc ttctttcctc aactatgtca
    25081 gatgatatgg gttctttagc aaaatttctt tcaatgaagc cagaacaaaa tatcgactta
    25141 gacttactag ggttaggaca tctaaatatg atttatttag ctttgaaaat agtcgaattt
    25201 gaagcgtgtc gttcaagaga actacttaat attatgttga ttgaagaacc agaagctcat
    25261 attcatcatc atattcaaaa aactctgttc gaaggattaa atcttcaaaa aaactatact
    25321 cagattctca tgaccacaca ttctgtacat ttagctgaag tgtctgaaat atctcggatg
    25381 aatgtattaa aatcgtttaa tggcaaatct atcgttatga atccagcaaa taatctgaac
    25441 tcatttgcta aagaaaagtt aaaaaagaac aatctaaatc taataaacgc agtagagaga
    25501 tatttagatg ttaaaagaaa tggattgctt ttttctaaag gtgttatctt agttgaagga
    25561 gatgctgaag aaatacttat tcctcaaata gtaaaaaaat tatttggtat aaacttagac
    25621 gaacttggaa taggtttgat taatgttggt agtacttcgt ttgaatatat cgctagcttg
    25681 tttgacgatg atagaataca gagaaagtgt gctattgtaa ctgatttaga tgaacaggca
    25741 atcccatcag aacatcgatt gtataaaagc actgcacaag agaaaggtca agcaagaaaa
    25801 gaaaaattat cctccctttt taatgaaaac aattgggtta attgttttta tgctaataca
    25861 acatttgaaa ttgagttttt agatgtgaat aaagaaaata ttctaactta tgtcagtcca
    25921 attatagatg acgcattcaa agataaaaaa acaataactg cttataaaga agaaatacaa
    25981 agtgaacaat atttagaaag aaatttagcg atgttaaaac tagccaatca tgttggtaag
    26041 gggtggtttg caattgagtt aggtgaaaaa attgactttt taatcaaaat tcctaagtat
    26101 attcttaatg ctattgcttt tgcatgtcag gaaatagtag atctctcaat ttataaaaaa
    26161 attctactcc atacaatcga cttgtacgag gaaactacag aattgtcagc tttatcagct
    26221 agtttaaaaa caagtgatac agctgatttg aatatagcaa taatttcttt attagagtac
    26281 tttggtaaag atgaggatgt tgtgtatcta atcaatcaga tagaaaatta cacaaaaata
    26341 ctttatgctg aggtttcaaa atgacaaata tcttcgaaaa aatcgtaaat gatttaaatt
    26401 tagaacaaaa agatgttgtg gaaagtgaag ataaccttta tgtaaatgca tgtcctggga
    26461 gtgggaaaac aagggtactt acaaggaaaa ttgcttacca agcaattaaa cacgatggat
    26521 cactaaaaag aataattgct atcacataca ctaatagagc tgctgaagaa attaaggaac
    26581 gcctaagttt acttagtata gatgatgata ttaatatttg ggtggggaca atacatcagt
    26641 tttgtcttga atttattatt tatcctttta aaatgaatct ctcaagagta tcaaaaggat
    26701 ttacaattat tgatgattat actcaaagag cttacgtcag ccaaattaat aatatgctga
    26761 atttaaatct caaaacgtat gaactgaaca aaattgattt gtcactttct catgatttta
    26821 aaattaatga agttcagtat actcaagttt ctgaaatgta tcacactatg ttggaaaaaa
    26881 ataaagaaat tgattttgat atgattttac tagtagcgta taaaatttta actgtaaaca
    26941 gtaacgttgc acgtaatatt gctagtaata taagggcgat ttatgtggat gaatttcaag
    27001 atactagaga attacaatac aatgtaatag ctaaattact tcaaaacaac cctcaaattc
    27061 agtcaatgtt tgttggagat attgaccaag caatttatgg atcattagat ggtatagcta
    27121 aatcagttga agaactagaa atgctaacta gtcacacttt tcaatcaaag acgctacatg
    27181 gctgttacag gtctaatcag agattagtag acttctactc taattttcag agttgtcctt
    27241 acgagattga aagcagaggg aataataaaa acgaccgtgg ttttataagt tatgattgca
    27301 aagttactaa ggaggattta cccaacataa taaaaaatat aataaaggaa aagattgaaa
    27361 gcggcattca tgaaaaagat atttgtgtac ttgctcctca acactatcct ctgttttcac
    27421 tgggtgagta tttaaagaaa gaattaccgt attgcaattt tgatgctata aatatatcac
    27481 caattaaggt aaataatcat agtttatttt tcaagttagc aattttgtac tttactgaat
    27541 caggtgaaaa ggttcgaaga agaaagctaa ttgcaaacga tattttaatt atattaaaaa
    27601 atgaatttgg aatagaagtt aaagattatt ttattgactt agatttatta cagctaataa
    27661 acagtgtgaa aagaatgtat agtggagacg acaacggtgt tgatttatac aaatttgtta
    27721 ccaaacatat atttgttaat cttaatattg acgagaaaaa ttacccgtct atttttaagc
    27781 actatctatt ttttattaac gaagtagaag atcggataaa aaataattca ttatctagta
    27841 gtgtatctag ttttaagaag atgtttaaat ctcgagatgg tatcacactt actacagcac
    27901 ataaagttaa aggaaatgag tatgatactg ttatcgctat taatcttcta aacgggaaaa
    27961 ttcctcattg gaatgaaatt tttaatgttt ctgataaagg aattagttca gcgagaaaac
    28021 tactatacgt aatttgttca agagcaaaaa ataatttatt tcttttctca gaggtgggtt
    28081 attttacgag taaaggagac ttgctttatc ccactcaatt attagataaa atagaatttg
    28141 attataatat ttaaaatacc taggtagtcg ttgttttaaa tatagtagga atcggacgct
    28201 cagtacggag cgtctatttt tttacccaat tttgaaagga agtgaactta tgaaaataaa
    28261 aaatcaagaa tcaaaaggtc gctctccccc ctttaaaacc atcacacaaa taagattcat
    28321 tcaaacataa aaacagaaag gataggtaaa aatatggaac ttaaatatgt cattcccaat
    28381 atggaaaaaa catttggaca attagaatat gctggtgaag ggaacattga acaacgtcga
    28441 ataaatggca gaccaaccat tctctctcgt agttacaatt tatactcaac gattcaacga
    28501 gcagatgata ttgttgtcat tcttccctcc gaagctggcg agaaacattt tgaatccgac
    28561 gaaaaagtca aactcatcaa cccacatatt accgcagaag gttataaaat tggcaatcga
    28621 ggatttacca attacattat gcacgcagac gatatggtga aagcataaga aaggaaaggt
    28681 gaaaaaatat gagattagca gaaggtattg tgattgaaaa agaccagaca tttggcacat
    28741 tgaaattttc cgccttgcgt cgtgaggttc gtatccagaa tgaagatggt acggtttccg
    28801 aagaaattaa agaacgtacc tatgacttaa aatcaaaagg acaaggacgc atgatacaag
    28861 tcagtatccc cgcttctgtt cctttgaaag aatttgacta caacgcagaa gtggaattaa
    28921 tcaatcctgt ggcagatacc gtagcgacgg ctacttttcg aggggcagac gttgattggt
    28981 acgtgaaagc agacgatctt gtattaaaag gacagacaaa acctcatcag aaatataaaa
    29041 aagaagcgtc cgaaagtgaa aaataggtgt tgcttatgac aaacacacca ttgattttga
    29101 aagaaattcc gaaggatgaa gccatttctt ttattcggca ataccattat tcaaagatac
    29161 tccctagatt gtgtaaatac tttctaggga ttttttcaga agaaaaatta ttaggcgttg
    29221 tggaattagg ctggggtacg caacccctac aaaccatacg caaactcttt cccgacagtt
    29281 cccttcaaac cacagattat ttagaaattg gaaagatgtg ttttcttcca gaaatgaatc
    29341 aaaccaatta ttttggcagt caagctcttt cagctctaat taagtggttg aaagaacata
    29401 cggactgtca ttttttatat acactggcag atggaattga gggaaaatgt ggctatgtct
    29461 atcaagcgtc caacttcttt tactgcgggt atttcaagac aagtgtctat cgtgataagc
    29521 agtcatggga aaagatacac cctcgaagtg ctcgcctttt attagaggaa aatgctcgct
    29581 ttgaacaggt agagaaaaag cattggcttt cccaggcatt ttgcgaatac aaagggattg
    29641 agaaaatcaa tggacgcatg tttcgctatc tctatccgtt gacaaaagaa gcgaaaaaac
    29701 tgttaggaca cactctctat cgacgtcatt attatccgaa agaaaaaaat ttacgctttg
    29761 aaaagcgaat cgcttatcag aaatatgaag ccatttctca accaactttt gataaacagg
    29821 ctcgtatcta caatacacaa ttattttgat aggtggaaag gaggattttt atgccattgc
    29881 ttcatgacag aggagagcga atcaaagcca acgataagca cttggtctat cattttgtac
    29941 taatttcatt gctggtagtt tttctagtcg tcctactccc ttttcattgg agagcgttac
    30001 aatcggtgaa ctggcaagca gttcagttag atacattttt ctatcaactt catacgccat
    30061 acttttggag cagtattctc actgctcttt ttgtatgcgg acttatcagc tggctttatt
    30121 atcactatcg tatagattct ataaaacagt tagagcaccg tcaaaagtta gctcgtatga
    30181 ttttagaaaa tcattggtat gaagccgaag aaactcaatc agagggattc tttaaagatt
    30241 tacccagcaa gaaaaccaaa caacgaatcc gccattttcc taaaatatat tatcgaatga
    30301 aagatggact aatccatatt catgtagaaa tcaccttagg gaaatatcaa gatcagcttt
    30361 tgcacctaga aaacaaacta gaaacaggat tgtattgtga attagtggaa aaaacgttga
    30421 aagattctta tgtagagtat gtcctacttt atgatactat tggcaatcga attggcattg
    30481 aagacgtggt agctcaagat ggacgtgtca aattgatgga atcggtctat tgggagttcg
    30541 attctctccc tcacatgtta attgctgggg gcactggtag tggaaaatcc tattttattc
    30601 tcacattgat tgaatctctc ctgcatacaa atgcaaagct ttatattctt gaccctaaaa
    30661 atgctgattt ggcagactta ggggcggtca tgaataatgt ctattaccgt aaagaagata
    30721 tgttggcatg tatcaatcaa ttttacgaag atatgattga tcgcagtgaa accatgaaac
    30781 aacaccctaa ctataaaaca ggagaaaatt atgcttatct tggtttgtct gccaattttc
    30841 ttatttttga tgaatatgtg gcaatgatgg atatgctagg tcgtgaaagt accaccgtta
    30901 ttcataaact caaacaaatt gtaatgttag gacgacaagc aggcttcttt ttaattcttg
    30961 cctgtcaacg tccagacgca aaatatttta gtgatgggat tcgggacaac tttaacttcc
    31021 gtgtggcttt gggtcgtatg tctgaaatgg gctttggtat gatgttcgga agcgatacac
    31081 aaaaacaatt tttcttaaaa cccatcaagg gaagaggtta cgtggataca ggaaaaagtg
    31141 tgattagtga gttttataca ccccttgtac caaaaaggta cgatttctta ggagaaatag
    31201 gaaaagtcat tcaaaaaaag caatctgagc ctgtaccgca cgaagtgaaa ggtacaggtt
    31261 cagacttgct ttgattggtg tggcgttagc cacgccaatc ctttagcccc ctctatctaa
    31321 caggggggca caaatacaac tgaaaacagg caattctcat caaccaatgt tgatggtaca
    31381 aaggattgcg gaaaatatga aaggtgtaaa ctcaagggtc atagtttaca tcttttttag
    31441 attggaggtt tgcgaatgga aaacgaaaaa atttggatta aggaattgaa agaaaagcga
    31501 ctggcttatg gcgtttctca aaataaactg gcggttgctt ctcatattac cagaccttac
    31561 ctatcggata ttgaaacagg caaggcagtc cctactcaac aggtgaaaga agatttactg
    31621 aacgctttgg aacgcttcaa tcccgataac ccattggaga tgttattcga ctatgtacgg
    31681 attcgattcc ctaccaatga tgtggctcaa attatcggtg aggttttacg tttgaatatg
    31741 gattatatgc tacacgaaga ctttggctat tattcttatc ccgaacacta tcgtttcggt
    31801 gatattgttg tcctagtctc tcatgatgta agtaaaggtg ttttattaga actgaaagga
    31861 aaaggctgtc ggcaatttga aaactttcta ttggctcaac atcggagctg gtatgatttc
    31921 tttcaagatt gcatggaaca taaaggtatt ttcaaacgct tggatttagc tatcaacgat
    31981 aaaacaggga ttttgaatat tccagatttg gcaaagaaat gtaaacagga agaatgcatt
    32041 tccgtctttc gaagctttaa aaattatcgc agtggtgaat tggttcaccg tgatgaaaaa
    32101 ccatacatgg gaaacacact ttatattggc tcattaaaaa gtgaagtcta tttctgtata
    32161 tatgagaaag attatgagca atacgtgaaa aatgatgttc ccttagaaga cgcagaagta
    32221 aagaatcggt ttgaaattcg gttaaaaaat gaccgagcca cccaagccat gaaagattta
    32281 ttggcacatc aacaggcgga aaaaacagcc tttgaaatta tcaatcgcta tatccgcttt
    32341 gcagataaag acgacactaa acgtcggagt gattggaaaa ctaatgaacg ttgggaatgg
    32401 tttatcggta aaaatcgtgg agcattacgc ctaaccacac agccagagcc ttattctttt
    32461 gaacgaacat tgaactggtt acatcatcaa gtcgccccta cattaaaaat cgcaagcatt
    32521 ttagatgttc tcaacggtac aaccattatc tccaccatga ttcaggaagc caaactgaca
    32581 gaaaaacatg agaaattaat tgaacaacaa catctagcca tggaggattt gattacatga
    32641 gccttttaac aaaagaatta aagaagttag ggtttcagtg tggcattgag tttcaagcgt
    32701 atatacaaaa tacagggaaa tatacgtctc tcattattga gggaaaacgg caagctggtg
    32761 ataccatcta tacctatgat ttttacaagg tgagatttta taataattat accaatcgag
    32821 taaccgtcta tggagagcat ttaacccctt ttcaattatt aaggcgtgta aaaagctata
    32881 tctattatcg agaaaaatat cttaaggaaa ggaggacaat cacatgaatt ttgggcagaa
    32941 tttgtacaac tggttcttgg ataatgcaca gtcattggta ttgttagcga ttgttgtcat
    33001 tggactgttt ttaggtttta aacgagaatt ttcaaaactc attggcttct tgattattgc
    33061 tctaatcgcc gtcggacttg tgttcaatgc agctggcgtg aaagatgtgt tattaaactt
    33121 atttaaccga atcattggtg cttaacagat atttttcatg ataaaatagg aagtatatat
    33181 tttgttatga aaggatttat gaatatgttt acaaatgatc aatttaaatc tcttttaatt
    33241 aaaacattag aaagaaagag ctcttcaaat tattatgaag gaggtaacga gattgtttct
    33301 aaaatgaaaa tatcagaggt aactttagat gagactgacg attttactta ttataaagga
    33361 tataaaaagg gctggaatac gctttgcaca tatcttaaaa taagagttcc ttttgatgat
    33421 ttagactttt ttgaaagtca taaagatttg attacccaga cagcaagctc catatatgat
    33481 aaacaaggtg ataatgtatt agtggatact attttagtac cacttccaga gaattacgaa
    33541 gtaattaact ttagtcagtt gaaaattagt gatgtggttt cacaagctat tgaagacgct
    33601 gagtctttta tgagtaatgg tgaatatcaa cgtgcctttg acagagttca cactgctttt
    33661 catggatatt taattgaaat actaaaaaaa tatgaaatta cagttcctag agacgaaaat
    33721 ctatctaaat tatatagtag gatacaacaa ttaattgaaa aagaaattca acctactgaa
    33781 cttgctgata tagtgaagac aacgataagg tcatcaaatg gaatgattag ctctcttaat
    33841 gaagcaagaa ataggcattc acttgcacac cctaatacaa atattattgg aaagagagaa
    33901 gcaaaactaa taataggtat ttcaagtaca gttacagatt atattagcgg ataccttgat
    33961 aagtagcgtc attaactgat tgctactttt tttatgacta tttttataaa aaggatgtga
    34021 taagaattgg aaatgaaagt ctatgtggca aatttaggac ggtataatga aggtgaatta
    34081 gtcggagcat ggtttactcc accaattgat gaggaagaaa tggcagaaag aatcggttta
    34141 aatgaggact acgaagaata tgcaatacat gattttgagc ttccttttga tgtggacgaa
    34201 tacacgccga ttagtgaaat caaccgtcta tgtgaagcca ttcaagaaat cgaaggtaca
    34261 cctatttata atgaactcaa agaaattcaa ggcatgtggt ttagtagctt ggaagaatta
    34321 ctggaaaaca aagaggatat tcattgttat agtgattgtg attcgatgga agatgtcgcc
    34381 cgttattacg tggaagaaac aggacagctt ggtgaagtcc cttccaattt acaaaattat
    34441 attgactacc aatctttggg acgtgatatg gaaatagagg gtaattacct agttacctct
    34501 catggggtat ttgaatattg tcagtaagtt taacaatccg tgttataatt aaattaataa
    34561 atagcacgga gaggtataaa ttatggtaaa tgtatttgaa aatcttaaac tattaaaact
    34621 agacatgaaa gataaaggct gggtgataga ttccttttac tttcgttaca aacagcaaaa
    34681 ttatattgta cttgttaagc tatttgaaaa agaggaaaaa gttccagaat atgctctgtt
    34741 aaaactagaa tttttaaagg aaaacgattt ttcagatatg ctagctgtct atgctaattc
    34801 ggtaaaatta tatacagaca cgaaaacaat aagagaatat tttggtatcg aatacagtag
    34861 taacttggga gatgttttat ttcaatttag ccaaactctt gctcgattta ttccgacaga
    34921 agttagtgag aagaaaaatg aagaccaaaa agaagccatg tgtttctcat taagtcaaag
    34981 tgattcagaa gatcccagaa aaaaatattg tttttcagtt agaagaaatc ctttaaaggg
    35041 aaatggtgag ctgggaaaac gaagtccttt taatgacaat aaaacgagat tgtatagacc
    35101 cagcttatat gaacgattag ggtcagatac caatttaagt ttcagatatt caatgaatcc
    35161 agatgatgaa gaaactgatg aaggtattat tgcaaaatgg acaaaaaata aaattgaata
    35221 gttaaagcat tgaaagagca atcacctatt ttgattgttc tttttctatt tttacggaaa
    35281 ggacgtgaag acatgaaaaa aataagaagt tacaccagta tttggtcagt agaaaaagtg
    35341 atttatgcga ttaatgattt acaactccct ttcccaatta cctttacgca aatgacatgg
    35401 tttatcgttt ctttgtttgt cgtcatactc tttggcagtt taccaccact ttctctgatt
    35461 gacggagcac tactcaaata cttagggatt cccattgttc tcactgggtt catgtgccaa
    35521 aagacctttg acggaaagaa accctatgga tttctaaagt ctatcattac ctatgctcta
    35581 cgccctaaag taacctacgc tggcaaacaa atacgattaa aaaaagaaac aatgaatgaa
    35641 tcgattacga ttgtaaggag tgaacaacta gatggcatat ccgattaaat atatggaaga
    35701 taatctcgta tttaatcatg atggcgaagt attcgcttat tatgaattaa ttccctataa
    35761 ttacagtttt ttaagttccg atgaaaaaat tcaagttcat gataatttct gtcaattgat
    35821 tgcccaaaat cgtgatggca agattcatgc tctgcaacta gcaaccgaat caagtattcg
    35881 agccacacag gaacaatcga aaaaagaaat cactggacga ttaaaagaga tagcttacga
    35941 aaaaatagat gaacagaccg aagcgttaat ttctatgatt ggtgacaatc aagtagacta
    36001 tcgctttttt attggtttta aactctacct caatgaacag gaagtatccg taaaaaatgt
    36061 tgggaaagaa attcaaaaag catttgcgga attctttcat ggtgtgaatc acaaattaat
    36121 gggcgatttt gtttctatgc ctatggcgga aatcgaacgc ttttctaaga tggaacagtt
    36181 gttagaaagt aaattatcca gacgctttca gattcgtaaa ttggagaaag atgattttgg
    36241 ttatattatt gaacatcttt acgggcaaac aggtgtccct tttgatgact acgactacca
    36301 tttaccgaaa cgatacgaag ataaaaaagt gttggtaaag aaatacgata ttctcaaacc
    36361 cactcgctgt ttaatcgaag aaaatcaacg ctatttacgg attgaacagg aagataccac
    36421 tacttatgtg gcgtatttta caattaatag tattgttggt gaattggatt tccctaatag
    36481 tgaaattttt tattaccagc aacagcagtt tactttcccc gttgatacca gtatgaatgt
    36541 tgaaattgtc gccaataaaa aagccttatc taccgttcgc aataaaaaga aagaactgaa
    36601 agatttagat agccacgcat gggaaagcga caacgaaacc agtactaatg tggtggacgc
    36661 tttagaatct gtcgatgaat tagaaagtaa tttagaccaa accaaagaat ctatgtacaa
    36721 actaagctat gtggtacggg tatcagcaaa gaatttggac gagctgaaac aacgttgtga
    36781 tgaagtaaaa gatttttatg atgatctgtc tatcaaatta gtacgacctt ttggcgatat
    36841 gctaggcttg cataatgaat ttattccctc aagcaagcga tatatcaatg actatattca
    36901 atatgtcacg tcggattttt tggctggtct tggtttcggt gctacacaaa tgattggtga
    36961 aaattctggt atttacgtcg gttacaatct cgatacaggc agaaatattt atctccaacc
    37021 tagccttgca agtcaaggaa ttaaaggctc tgtaacaaat gcattagcgt ccgcttttat
    37081 tggttcatta ggtggcggaa aatcattctc taacaatatg ctggtctatt attcagtact
    37141 ctttggcgga caggcaacca ttgttgaccc aaaagc
//
LOCUS       DAFEEZ010000021        36853 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000021
VERSION     DAFEEZ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36853
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.021"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(324..893)
                     /locus_tag="LP245_001167"
     CDS             complement(324..893)
                     /locus_tag="LP245_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL1519097.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(967..2256)
                     /locus_tag="LP245_001168"
     CDS             complement(967..2256)
                     /locus_tag="LP245_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519098.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESENKSKLTKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQAFAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            2610..3458
                     /locus_tag="LP245_001169"
     CDS             2610..3458
                     /locus_tag="LP245_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBL1519099.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPVPVR"
     gene            3472..4545
                     /locus_tag="LP245_001170"
     CDS             3472..4545
                     /locus_tag="LP245_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBL1519100.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKREISFPVTVL
                     PAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKLSAHTQEWLY
                     REYDYQEEECSPLFCFWGSHSPKFEPLLDLYFSLWHLRKEKQPELLILGNRAFHGKDP
                     GHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKDRTVYLVYFV
                     EKQLMVQEKDKICSLPGGEWIDD"
     gene            4535..6706
                     /locus_tag="LP245_001171"
     CDS             4535..6706
                     /locus_tag="LP245_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBL1519101.1"
                     /translation="MTIKWEKWLCGVYSFVILSVGAPIFVVANQLQNSYLLILTIGVL
                     CLIVCCIPKKWVRLLLSLPVMIGCLFLYFPSKTFSLLWILQFFSSVTEEFFHLSQGKL
                     YYLPEKTAFFLIMLLIYLFITLTVDYDYLYAPFLSLMAYFMMLTVFREKDLLYEMIAV
                     VTVLFVYLAARQFFSMRLLSGNTRFQSLTTVLLICFLTISAILPLYLPKVHQSLEETS
                     EPIREYLNDEGLYDTLHEYQLTGSARTGFSENDEQLGGPLYDNGEVVFTANQKGNGYW
                     KIENKNHYTGSGWIEDQDAPIQPIQEFPVDITSYQTVMEDKENITLTLKKQAFLPYPY
                     GNTTLTDFSLASGQTLYYLPESQRFIPVPNESTRSATLQTERLVFTREELKSSQLKAD
                     DLENQQTNLQLPKSLPKRIEDLAVELTKNEATLIRKVEAVEQYLKTSGNFRYSKTDTG
                     HTPKEHDYVDYFLFDSKVGYCDNFSTSMVVLLRTLGIPARWTKGFTNGLRTGTDNQGN
                     EEYSILNSHAHSWPEVYFPGFGWLPFEPTPSFANPMGSQPVAETTETVQPAIEQPNES
                     ENMAETISSERSEVIPSEETTLTPAYKIVLFSLGVCLYVLLFFLLLFRKSLRWTSYLI
                     YLHFFASTNTIAYQKLLNHLETLVPRKPAESLQEYSLRIEQEFKLDLRFIRLTTQYEA
                     EIYGRQADPVNFDKKTYLEITHIIRKTVYKKVLTKGSRFKK"
     gene            complement(6818..8989)
                     /gene="copB"
                     /locus_tag="LP245_001172"
     CDS             complement(6818..8989)
                     /gene="copB"
                     /locus_tag="LP245_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBL1519102.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHDHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKNQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9009..11195)
                     /locus_tag="LP245_001173"
     CDS             complement(9009..11195)
                     /locus_tag="LP245_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBL1519103.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKSKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMSSSLASIAQTIELSRVTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(11195..11404)
                     /gene="copZ"
                     /locus_tag="LP245_001174"
     CDS             complement(11195..11404)
                     /gene="copZ"
                     /locus_tag="LP245_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBL1519104.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(11417..11857)
                     /locus_tag="LP245_001175"
     CDS             complement(11417..11857)
                     /locus_tag="LP245_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBL1519105.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(11931..12404)
                     /locus_tag="LP245_001176"
     CDS             complement(11931..12404)
                     /locus_tag="LP245_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation family protein"
                     /protein_id="HBL1519106.1"
                     /translation="MGRENRPSQGRSKKSPAFRIQAKKWFLQEQQSFMVSNPSWIVEG
                     NYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLKRKINKKSRPDMPESFSEKLNRK
                     YLEFLSFIWHFEGNNEPKIQQLIQVANARNKLIILKTRREKQEFLTKLKIESKNN"
     gene            complement(12714..14180)
                     /locus_tag="LP245_001177"
     CDS             complement(12714..14180)
                     /locus_tag="LP245_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1519107.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(14491..16575)
                     /gene="cadA"
                     /locus_tag="LP245_001178"
     CDS             complement(14491..16575)
                     /gene="cadA"
                     /locus_tag="LP245_001178"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBL1519108.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKKRNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTAEGLMTVNPEDVLIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     RAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDPTGIDPKKFMQYVASAEQFSTHPIAQSVLEGYAGPLL
                     PTANIQEFAGEGILAEVDGKQVLVGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGY
                     LVIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDK
                     VQRLEEILQSNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQP
                     SKIAEAIHLAKKTLKIVKQNIVFAIGIKILVLSLGAFGFASMGDAVFADVGVTVLAVL
                     NAMRSLHVKNKR"
     gene            complement(17099..17458)
                     /locus_tag="LP245_001179"
     CDS             complement(17099..17458)
                     /locus_tag="LP245_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBL1519109.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(17488..17829)
                     /locus_tag="LP245_001180"
     CDS             complement(17488..17829)
                     /locus_tag="LP245_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519110.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(17826..18500)
                     /locus_tag="LP245_001181"
     CDS             complement(17826..18500)
                     /locus_tag="LP245_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL1519111.1"
                     /translation="MKKRILFIGDSITDAGRYRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIVAVDFFSGDKNE
                     RKKSEK"
     gene            complement(19295..20593)
                     /gene="asnS"
                     /locus_tag="LP245_001182"
     CDS             complement(19295..20593)
                     /gene="asnS"
                     /locus_tag="LP245_001182"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBL1519112.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKITFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(20633..21823)
                     /locus_tag="LP245_001183"
     CDS             complement(20633..21823)
                     /locus_tag="LP245_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL1519113.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(21844..22371)
                     /locus_tag="LP245_001184"
     CDS             complement(21844..22371)
                     /locus_tag="LP245_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBL1519114.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(22418..25207)
                     /locus_tag="LP245_001185"
     CDS             complement(22418..25207)
                     /locus_tag="LP245_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBL1519115.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDSSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAIYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKEIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHAFFADIAHRGTGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(25354..25554)
                     /locus_tag="LP245_001186"
     CDS             complement(25354..25554)
                     /locus_tag="LP245_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1519116.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(26006..26326)
                     /locus_tag="LP245_001187"
     CDS             complement(26006..26326)
                     /locus_tag="LP245_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519117.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(26627..27745)
                     /locus_tag="LP245_001188"
     CDS             complement(26627..27745)
                     /locus_tag="LP245_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519118.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            28216..29523
                     /locus_tag="LP245_001189"
     CDS             28216..29523
                     /locus_tag="LP245_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBL1519119.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFDNLF"
     gene            29642..30841
                     /locus_tag="LP245_001190"
     CDS             29642..30841
                     /locus_tag="LP245_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBL1519120.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYAWQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(30868..32136)
                     /locus_tag="LP245_001191"
     CDS             complement(30868..32136)
                     /locus_tag="LP245_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBL1519121.1"
                     /translation="MEKQLPSPMRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLITLTL
                     FGTITTHLFGGSVGREGTAVQMGGSLADNTARLFRLDKAEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(32299..32946)
                     /locus_tag="LP245_001192"
     CDS             complement(32299..32946)
                     /locus_tag="LP245_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBL1519122.1"
                     /translation="MEQTIKPYQYFFIKREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILNHELPEIDTFLTTVLDVKLTKAQAERALEKLKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(33354..33857)
                     /locus_tag="LP245_001193"
     CDS             complement(33354..33857)
                     /locus_tag="LP245_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1519123.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(33980..34744)
                     /locus_tag="LP245_001194"
     CDS             complement(33980..34744)
                     /locus_tag="LP245_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBL1519124.1"
                     /translation="MKEIQSVKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSSADQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            34851..35126
                     /locus_tag="LP245_001195"
     CDS             34851..35126
                     /locus_tag="LP245_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBL1519125.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            35842..36792
                     /gene="yidC"
                     /locus_tag="LP245_001196"
     CDS             35842..36792
                     /gene="yidC"
                     /locus_tag="LP245_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBL1519126.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVIMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
BASE COUNT        10593 a         7759 c         6535 g        11966 t
ORIGIN      
        1 gtcaaggaca atcggaatag catacggaaa gaagttctgc accttataaa atttgtcaaa
       61 aaaactgttg ccattccaag tgaaaaaaag atcaatgaat caactagaaa actatataga
      121 agagcaaata aaaaagcact caaattgagt gcttttttaa gctcactatc actaaaacta
      181 tcactaattt tatttataag cgaacatgtt tctatcactg attttttaaa tctagcgaaa
      241 aacccttatc ttaaaggcgt tcgttcaatt ctttggcaag gtcttcaaag cctggcttgc
      301 ctagaagtgc gaacatggtt ttcttatagc tcatgtagaa aaattttctt gatgatgatt
      361 ttatccatca attgagattg actgttttgc tctcctatga tttcagctat gattgtccga
      421 ttttgcggtt ttcttcttaa ctggtagttg attttcccag tttccatcaa ctcgctaagc
      481 atatccacga ctccgccaaa tccggtcttt ttcgtaataa aacctagtgc taccattcgt
      541 tcatctagat tttttgctgt aatcgtcaca ccagtaatga gcgagtgctg taatgtttgg
      601 gccagctctt ccatcccttc agcattggat acgacggaag ctgttttgtt aataggttct
      661 tcgtttattt cttttggttc tttcctctcc actttcactg tttgacgaag gacatctagt
      721 tcttgcaaga gcgtttcgta ttgttcttgg gtcagcatca cgccagctac tttttcacga
      781 ttaaatatat atacgccagt tcccgcgtct cgcgcttgag caaatacatc catcggcgat
      841 cgtttcactt ctgtgatcga agatgtggga acttctaatt tctttaattc caatggattt
      901 cctcctttac taatcgcttt ttattatagc acagactgac ttgttttgat cttttttcca
      961 aaggttttat cggtttttgc ctaaccagta attgatatcg gtaagaagtc tttcgatacc
     1021 aaatgaagga tggtacagat acgttttttg atcttcgtta tggtctagtg gaaaaaaatg
     1081 atcggtgatc actagatctg cataccgagg cggcttattt cgagtacata catgtataga
     1141 gatccgtttt cgatgtctta gcgttttgtt cagtacccca gcaagtcttc ttgcttcttg
     1201 gtgttcatag cgaaaaaaaa agacgatttt cacttcagga gggtggacat ctaaataccc
     1261 tcgttcctgg agtgttttca gtaaaagcat cccccactct actgcggggt gtgcaaatgc
     1321 ttgttggatc gctagccgaa attgatatag tttatctttg gaattgggaa atttttctaa
     1381 tgtttcctga taataacgaa cttcttctat cagccggtca tggataccaa ttacgtaacg
     1441 aagccattct tggtaaagta cttttgtcag ctttgatttg ttttcgctct caaattcgct
     1501 attcagccaa aacagcgaat caagcttttc agtcacaatc gtcaatttcc gatagtcttg
     1561 tgtctcttct atccgtttcc accgcttttc agtaatctgg ttacagctca agcgcaaaat
     1621 tgctagataa tttttttctt ttattggcaa aatctgctct tctctaaata gcaattcagg
     1681 aaacaattca aagaatagtg ttcgactgtc tcctaaaatc tcgatttctg ccggatcctt
     1741 tctttgcttc aataattgga tgaacatctc agaaaaggac tgctctccat catctgcaaa
     1801 aaaatgcgga aaatctttca aaaagcaaaa cagcagatat cttacttttc tttctgaacc
     1861 aaagatctgt gcttttttat aagaaaaaga aaggtggtac tcgccaaacc actttctcaa
     1921 tcgctcttgc gtagaacgat cgtacttctg ctcgtaaggt tcattcaata gcagattttt
     1981 cagtaaacaa aacgggggtg attggatcag aaaaacaaac aagagataag gttcgctata
     2041 tccttgatca taaactaact gaacggtttt cttatgaaga atcagctgga tgggacagtc
     2101 gctttccgcc aaacgtttca gatgccgatc cactgtttta acatcgattt tcagttcttc
     2161 agctaaatca gcttttcgcc agatcaaatc tttcattaga ttgattagtg aaaataaatt
     2221 ctgtgcattt tttgataata gtttttgcca tctcatcgat catttctcac ctgatttcta
     2281 aacatattgt ttgatcaaaa tgggttcact cctaaaaaga taaaaaactc cctttctatt
     2341 tatttaaata cgcaaatttt cctcattatt tttaatttta ctcaatttaa tcgtattctc
     2401 atttcaaaac gaatgtactt taaaaaaaca taataaaatc actttgcttg taggatgtat
     2461 tcccttccat tacaatgaaa taaatagcaa ttttatgaga aggtgatgtg aaaatggaag
     2521 aaaaaatcga agaatccaaa caaaaaatcg atcagttgat acaagaatta gaaaaagcgg
     2581 tcatcggcaa acgttcaact atccaattga tgatcgtggc cctattagca ggtggtcatg
     2641 tcttattcga agatattccc ggtgtaggta aaacgttact ggtcaaagca ctagcaaaag
     2701 ctgtacaggg aaccttcagc agagtccaat gtactcctga tctgctgcct agtgatattc
     2761 ttggtttttc cgtatacaat tcacaatcaa aagagtttga atttcgtccg ggaccgatct
     2821 ttaccacgat cttgttggca gatgagatca atcgcacgac tcctcgtact cagtcagcac
     2881 ttttagaagc aatggccgag aatcatgcaa cgatcgacaa caatacatac cctctagaca
     2941 atcatttttt tgtcttagct acgcaaaatc caatcgagta tgaaggaaca tatcctttgc
     3001 cggaagcaca gctcgatcgt tttttattcc gactacaaat cggttatcct tcttttgatg
     3061 acgaactttt gctactttta gataaattcg aaaaagtgtt ggataactta aatgaagtat
     3121 tgaacagtta tgaaatagaa gaaataaaaa caaatgtggc gaatgtcttt gtcagtcccg
     3181 aagtggcatc ttatgccttg cagttagtgt cagcaacaag aagccatgct gccatccagc
     3241 ttggcatcag tccacgagga agcctttcct ttattcaggc agcaaaagct tatgctttaa
     3301 tccatgggag aaattacgtc acgcccaaag atttgcagga tttagttcct tacgtgtttt
     3361 cccatcgcct gattttttac gatcgttcat tgaaggaaga cgaaaaaaaa caaatcattc
     3421 atactcttgt tgcacaaatt cctgttcctg tgaggtagat tgaggtagat aatggaaaaa
     3481 atcaaagatt atttcattaa ttttgtgtta tttctggtat atttcatcat tgtgcttttt
     3541 gctcttgtat tcaacaattc tttaggctgg ttcttgttgg ccttttttac tctttatgta
     3601 tcatggagct tgatttcatt aagcagcttt ctaaagaaac tttcggttac ttgtacattg
     3661 cagccactcg tttatcgcaa aaaaagtatg caggttattt tttccatagc aaaaaagaga
     3721 actttttctt tacctctccc tcgtttacaa atcggcttcc cagcaatctt tgcagaaaaa
     3781 aaacaagaga ttttgattct tacaaataaa ccgcaagaag tccaattgct ttggcagcca
     3841 aaagaaagag gatgccatga aacattaact gtcattttta cagcctatga tagtctagga
     3901 cttttcagaa aaagtgcaaa aagagagatc tcttttcctg tgactgttct gcctgctttt
     3961 tgtaagattc aagcagaaaa attacagaga gttctggaaa aaaaacagca gctgaacgcg
     4021 taccaaagag gtcttgattt tcgggaacat cgcgcttatc gtccaggtga ttctttcaac
     4081 cgaatcgatt ggaaattgtc tgctcatact caagagtggt tataccgtga atacgattat
     4141 caagaagaag aatgttctcc tcttttttgc ttttggggtt cgcacagtcc aaaatttgaa
     4201 cctctgctag acttgtattt ttctttatgg catttgagaa aagaaaagca gccggaactt
     4261 ctgatattag gcaaccgcgc ctttcatggc aaagaccccg gtcataccta ttttgcttct
     4321 ttggaagctg gcgatgagaa agcttttttc gcacacctaa aaaaatatgc aaaaaaacaa
     4381 atcgtcctct ttgttcctga gaattctcct gaagtctcag aagctattga aacattgtca
     4441 aaagatcgaa cggtttatct tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa
     4501 gacaagatat gttcattgcc aggaggtgaa tggattgacg attaaatggg aaaaatggct
     4561 gtgtggcgtt tactcctttg tgatactaag tgtaggtgct ccgatatttg tagtagctaa
     4621 tcaattgcaa aacagctacc ttcttatcct aactattggt gtcctatgcc ttattgtctg
     4681 ctgtattcct aaaaaatggg tacgtttgct gctttctttg ccagtaatga taggttgttt
     4741 gtttttgtat tttccttcga agacattttc cttattatgg atcttacagt ttttttcgtc
     4801 agtcacagag gaattcttcc atctatccca aggtaaactt tattatttgc cagaaaagac
     4861 agcttttttt ctcataatgt tgctgatcta tttatttatt acattgaccg tggattacga
     4921 ctatttgtac gcaccctttc tttctttgat ggcttacttc atgatgctta ccgtttttcg
     4981 ggaaaaagat ttactgtacg aaatgattgc ggtagtaact gttttgttcg tgtatctggc
     5041 agcaaggcaa tttttctcca tgcggttgtt gtcgggaaac actcgattcc agtcattgac
     5101 tacagttctg cttatttgtt tcttaactat tagcgctatc ttgcctttat atcttccgaa
     5161 agtacaccaa tctctcgagg aaacgagtga accgatccga gaatatctta atgatgaagg
     5221 gctttatgat acactccatg agtatcaatt aaccggaagt gcaagaacag gcttcagtga
     5281 gaatgatgaa cagcttggtg gacctttata tgataatggc gaagttgttt ttacagcgaa
     5341 ccaaaaagga aatggctatt ggaagatcga aaataaaaat cattacaccg gttctggatg
     5401 gatagaagat caggacgcac ccatccaacc aatccaagaa ttccctgttg acatcacgag
     5461 ctaccaaacc gttatggaag acaaagaaaa cattacattg accctaaaaa aacaagcttt
     5521 cttaccttat ccttatggaa atactacctt gactgatttt tcattagcta gtggacaaac
     5581 gctttactat ttgcctgaaa gccagcgatt cattcctgtc ccgaatgaat cgacacgttc
     5641 tgcaacttta caaacagaaa ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt
     5701 aaaagctgat gatttagaaa atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa
     5761 acgtattgag gacttggcgg tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt
     5821 cgaagctgtc gaacagtatt taaaaacaag cggaaatttc cgctattcca aaacggatac
     5881 cggacatact ccgaaagaac acgattatgt ggattatttc ctctttgatt caaaagtcgg
     5941 ctattgtgac aacttttcaa cttctatggt cgtccttctt cgaacacttg gtatcccagc
     6001 tcgctggaca aaaggtttta caaatgggct cagaacaggc acagataatc aagggaatga
     6061 ggaatacagc attctcaata gtcatgctca ttcttggcca gaggtatact ttcctggatt
     6121 tggctggctt ccatttgaac caaccccttc atttgccaat ccaatgggtt cacaaccagt
     6181 tgctgaaaca accgaaaccg tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat
     6241 ggcagaaact atttccagtg agagatctga ggtcattcca tcagaagaaa caacactcac
     6301 accagcttat aaaatcgtct tattcagcct tggggtgtgt ttatacgtct tgttgttctt
     6361 tctattgtta ttcagaaaat ctctgcgctg gacaagttat cttatctatc ttcatttttt
     6421 tgcttctact aatacgattg catatcaaaa acttcttaac catttggaaa cattggtacc
     6481 gcgcaaaccc gcagaatctt tgcaggaata tagcctgcga atagaacaag aattcaagct
     6541 agatctgcgt ttcattcgat taactactca atatgaagca gaaatatatg gacgacaagc
     6601 agatccggta aatttcgata aaaaaaccta tttagaaatt acgcatataa taagaaaaac
     6661 ggtatacaaa aaagttctga caaaagggag ccgcttcaaa aaataagata aaatttctgg
     6721 agaatctact tctggaatgc cgagaaccag ctgcttgagt atcgattatt cgaaaaaaag
     6781 gttgtgacac gttttttgtc acaacctttt ttcattatta tttgattttc aatgtcaaag
     6841 catttagagc tacaactacc gtacttaacg acatcaagac agcaccaact gctggactta
     6901 atatgatacc aattggcgca agaattccgg ctgctagcgg aattgcaaga atattgtaac
     6961 ctgcccccca ccagaggttc tggatcattt tctttcgcgt ttgcttggct agatcaagaa
     7021 aatgcaaaat atcttttgga tcgctgtttg tcaatacgac atccgcagaa tcgattgcga
     7081 tatctgtccc tgcaccgatt gccatcccga ttgaagcacg ggctaaactt ggcgcatcat
     7141 tgatcccatc acccaccatg attacttttt tcccttggtc aaggtatttc tggacaacag
     7201 cttctttatc atctggtaat aaaccgccat aatattcttc gatccctaaa taatctgcta
     7261 ctgcttgggc agcgttttta ttgtcaccag taagcatgac aggagtgatt tttctttctt
     7321 tcaatgttcg gataaattct tttgcttctg tttttactac gtcacctaaa gcaacgattg
     7381 cagctagatg attttctaaa atcaggaagc tgatggtatt tccttgttct tggtaaggtt
     7441 tcaataatgc ttgttctacg tttaatccga gacgctcaac ttctttttca ttaactattt
     7501 tcacttgttg gtttttgact gttgcctcta gcccaactcc tgaaagattt tttagatttt
     7561 cggcttgata aggcttgatt tcatgttctt tcaaataatt cataatacca acagccaatg
     7621 gatgattggc attcgcttcc aatgctccta aatattgaag gatttcattt ttattgaacg
     7681 catcatcaag tacttcgaca cccgttacag taaattttcc ttctgttagt gttcctgttt
     7741 tgtccagcat gatcacatct agatcattgg cttgctccag tgcattgcgg tttttcaaaa
     7801 gtaatccgtt tttagctgct attgatgtag agcgagcaac aactaatggg atagctaaac
     7861 ctagagcatg aggacaggcg atgataaaga ctgttaccat acgttctaat gcattaggaa
     7921 gatctgtcaa gaacaaccag gcgatgaatg ccaggatacc cacaattaat gcgacataaa
     7981 acagccattt tgccactttg tcagataatg actctagctt ggatttttct ccttgtgctt
     8041 ttcgcaccat ttccataacc ttcgctagat aaccattttc accagttcca gttacttcga
     8101 tttcgatcgt tccatcccca ttgatagaac cgccaatcac tttgtcattg gcttgttttt
     8161 tgattcctct tgattcgcca gtcacagctg attcgtcaac aattgtttca cctttcaaga
     8221 ttacaccatc tgttggcatt ttatcaccag accggacgat caaacgatca ccttcgttta
     8281 cttctttcaa tgaaactgtc tcttcttttc catctttcgt caagcgtttt actgattctg
     8341 gcagtaattc tgctagtttt tgtaaagcat tgctggcatt cgacacagca ttcatttcaa
     8401 tccagtgacc tagtagcata ataacgatca aagtagccaa ttcccagaag aaatccatga
     8461 cgtgtgtatg tggattgagc agatttgcga taaacgaata gacactataa atatatgcaa
     8521 ctgtaatccc catcgcgatc agtgtcatca tagcaggact tttttgtttc aattccatct
     8581 tagctccact taaaaatggc tgaccgccat agataaatag tatagttgct aagatcaata
     8641 cgagccaatc agaaccagga aacgttactt gaaatggaaa ttccattccc atcattggtg
     8701 aaaaaagaat gattgggata gctaggataa gcgatagcca aaatttttgt ttgaaatttc
     8761 ccatgtgcat ggaatgatcc atgccgccat gatcgtgatc catgtgcatc gaatggtcca
     8821 tttgtttgct gtttgctata tctccatggt tatgtcccat gtgcatggaa tggtccatct
     8881 ggctatggtc atgtttcatc tccatctgtt tttcatgaga ttctgtactt tctttgttta
     8941 ctacttcttt tttatgttca tgttttttct ccatatcgtt cccattcatt tttactccat
     9001 cccttctctt actttttcat gtgccgattt aagctcaggg agttcaacaa tacactgacg
     9061 gaactaaacg ccatcgctcc tcctgcaatg attggattca aaaagcctag tgcggcaaaa
     9121 ggaataccaa tcgtattata gacaaaagcc cagaaaagat tttgtttgat ttttctcaat
     9181 gtcaccctag acaactcgat tgtttgtgca atggatgcca aactgctact catcagcgtc
     9241 acatcggctg tttccatcgc gatatccgtt ccacttccca ttgccatacc aacatcagct
     9301 aatgctaaag ccggtgcatc attgattcca tcgcctgcca taccgacttt tttgccatct
     9361 ttctgaagtt tttctacgta ggctgcttta tcctctggaa gtacttcagc aaagatatgc
     9421 tttggatcaa taccaacttg tttaccaatc gtttcggctg ccagtttgtt gtctcctgtc
     9481 agcataaaaa catctaatcc tttattctgg agctgcttga ttgcttgttt ggcttctagt
     9541 ttgatttgat cagccacggc aatcaacccg atcacttgct tttcatcagc taaaaacatg
     9601 actgtttttc cctgctgttc taattctaac gcgtgttctt ggtattcatc aaatgatagg
     9661 ttcaattcaa ttaatcgttt acgtgtaccc gcaaaatagc gtactccgtt aatcgtaccg
     9721 ctgattccag cacctgggtg agctgtaaaa tcaatcatat cgtatgttgc tgcttcttgc
     9781 agttttccgt attccacgat tgctttacct agtggatgtt cagaagcttg ttctaaagta
     9841 taaaaaatag ataggacttc tttagaaccg actagatctg taactttggg ctttccttct
     9901 gtaatcgtcc cagttttatc caaaacaatg ctgtctaagt gagcagctgc ttctaatgct
     9961 tctccgcctt taattaaaat tccatttcgt gcaccaacac ccgttcctac cataatagct
    10021 gttggagtcg ctaaacctaa tgcacatgga cacgcaatga ctaatacaga gacactatgg
    10081 atcaatgcga gttgccaatc accagtgatc aaacctgtag ctatgagcgt gataaacgcg
    10141 atgactaata cgatcggaac aaaaatccct gagatccgat ctgcgatttt ttggattggg
    10201 gctttgctcc cttgagcatc ttccaccatt tgaatgattt gcgctaatac tgtctgcttg
    10261 ccgacttgtg tgacttccat gtgtagcaga ccattcgtat tgattgtccc gccaaaaagc
    10321 gtgtcatccg gattcttttc tacaggaaga ttttcaccag taagcatact ttcatctatc
    10381 gcactgcttc ctgaaataat tcgaccatct gctggaatct gctcaccagg acggatgact
    10441 agttgatcac caacgactac ttcttcaatc gctaacgttt cttctttccc gtttcttatc
    10501 acttgggcgg tttttgtttg aagagacatc aattgtttga ttgcattacc tgttttcgtt
    10561 tttgctgtat gttccaaata tttgccgagc aaaatcagcg tgatgatcat actgctgctt
    10621 tcaaaataaa gatcttgggg gtgtccacgg aaaaatccgt tgtaaatgct caatgcaaag
    10681 gcagccgatg ttccaattgc taccaataca tccatatttg gtgctttcga cttgattgca
    10741 tggtacgcac ctttataaaa acgagcaccg acataaaatt ggacaggagc agacagcact
    10801 aactggacga ttggaaaatg aaaaaagtga acaatcgccg catggcttcc taacatcata
    10861 gcaatcattg acaacatcaa cggcaaagtc aaaaccgtac tcaatataag atcgaatagc
    10921 atttttttca aatacgcttg cttttcttct gcaatttttt gtttgtgggc ttcatcgtac
    10981 aaaattgcac catagccgat gttttctacg ctttggatta atttttcagt ggtcgtccct
    11041 tcatatttga cacttgcttt ttcagtggcc aagttgactg tggcattgac cacaccaggt
    11101 tgtccgttca gctctttttc gatcctagca gaacaatttg cacaagtcat acctgtaatg
    11161 acgaacgtat ccattttggt ttctgctgtt gccatcaaat cacctctgct ttataaccca
    11221 atccattgat tgcttgacaa atcttttcgg attgaacttt tgtttcatca aacttgaccg
    11281 taccgtttgc ttttttcaaa tttactttca ctttttgcac gccgtcaagt gcgcttactg
    11341 tttcttctac tcttgctgca caatgattgc agctcatacc ttcgattgaa aattgttgtt
    11401 tcattttttc ttcctcctat tgatgttgtt tacattcaca ttgacctggg atacagttac
    11461 attcgatcgt atctactggt tgcttttgtt ccagttgttt caaaatctca ttgatatctt
    11521 cttgagtcaa agtggcttct tctactagat ccgcaatcgt ctctccaatc ctttttgcac
    11581 agatatggga aaaaagattt tccgtcgcac tgcgaactgt ttccatctcc gagacagctg
    11641 gatgataaat gaattttttt ccttcttgtt ctgtccagat cacttctttt tttaccaaac
    11701 gacccagcaa agttttgatc gttgctggtt tccaatccat cgaatcagct aagatctgcg
    11761 tgatttcttg ggctgtcgtc tgtccaagtg tccaaataac acgcatgatc tcccactctg
    11821 aatcactaat ctttactggc gttttgactt tttccattta tttcacacct ttcgtttaca
    11881 aatgtaatca ttaacttatg aatacagatt acacttgtaa acaaaaactg tcaattattt
    11941 ttgctctcta ttttcaattt agttaaaaat tcttgtttct ctcgtcttgt tttaaggatg
    12001 atcagtttat ttcttgcatt agctacttgg atcagctgct gtatttttgg ttcattgttt
    12061 ccttcaaaat gccagataaa agataaaaat tctaagtatt tcctgtttag tttctccgaa
    12121 aatgattcag gcatatctgg ccgagatttt ttgtttatct ttctttttag agaacgccaa
    12181 actactcggt agatggcgag ataacgcggc actttaagcc aaatgatctt atctgcttct
    12241 ttaatccttt cctctaacgt agaagtataa tttccttcaa cgatccatga cggattagat
    12301 accataaacg attgctgttc ttgcaaaaac cacttttttg cctgaatgcg gaaagccggt
    12361 gatttctttg atcttccttg cgagggacga ttttcccgac ccactttgtc caatcacgat
    12421 gatcttcatt cttctccctc acttctcttt ggaatttggt tcgatcatac cacttataac
    12481 gccgcaaaaa aacaagggac tgtgacaaaa gtcgtgtcaa agtcccttgt ttcgaataaa
    12541 tggtgttcaa tcagctgacc ttcagcatta gctcaaaaaa cggcaaaata tgaggagcta
    12601 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    12661 cggtgttcca gaagtagctt ctgtcacaac ctcttgtaac aagtatttct attttaaggc
    12721 tgaaccactg tttctggttc agtaatttct ttgtttttgt ctcgacgagc aattgctggc
    12781 aagatcatac ctaataagat caagacaatt ggtgtgatga tattcgtgaa taattggaac
    12841 caccatgctt taggatcagc agtataatct acttttggca ccattcctag gatacatgca
    12901 aacgcagtga aggcaaagca ccaagcacca aagataaaac cgatttttgg atttttaaca
    12961 aatttatatt cagaattgaa tttcttataa gctttattca acatcatata tgccaagaac
    13021 acccataggt aacgcattgg catgacaact gagttcaagt tcgtcaacca ttttactaat
    13081 tcattcatat ctttgatacc aaagatcggc aacaaaataa tgattcctac tagtatacct
    13141 gtcagaagat aaccattcac caatgtacct ttacgattac gtttacgtag ccagtttggt
    13201 acaaattctg gatccgcatc tgctaacaag atttttagtg gtgcatcaat tgaaaaggct
    13261 aatgcggaga tttgtccaat catgtttgtc aatgcgtaaa tgatcatcaa tgagttaccg
    13321 ataccatagt aattacctaa aatttgaaaa gcactgtatg ccccatttgc catcaagtct
    13381 ttagggatat tatcgctagc aaacagcata cccattgcga ctgagcctaa tacagcacaa
    13441 atccctacca ttgctgctaa gaagatcatc cctttaggaa attcctttgc aggatttctt
    13501 gtagagttga cataagggga tattttttcc gcccctccaa ctgcaaatac tagcatcgaa
    13561 acggttgtga aataactgaa atcaaatgtt ggaatatatg ttttcacttg attcatatgt
    13621 ggtgtggcaa attccatcgt tggattgatg aacggtgccg ttacagctaa aagaataaat
    13681 aagatcgaca tgacgaacat cgctgttccg gccagtccgc caatcacttt caaagtagaa
    13741 agtccttttg ttgataaata taaaaaggca agaaatataa taagtgaaat aactgctacc
    13801 atttgtactg acatcgtatt tacgatattt ccatttcctt ggactgccca accaccagca
    13861 atcagaattg cttgaggctt ttgtgccaaa taaggaatat ggacgaccca gtaagtccaa
    13921 gcggcatagt atgccagtcg tttattagat gtcgtatttt cgacccatga actgacgcct
    13981 cctttactat ccttgaaggc tgatcctaat tgtccaacga tcaatgcgta tggaataaaa
    14041 taaatggcca aaatcaatag ccaagaggtg acaactgata ctccttgctg agcatagtta
    14101 ttaactacat tccccatgcc ccaaaccatg ttaaatgcaa ttaacgcaac agtaaaccag
    14161 cgtaattgtt tgttgttcat tcgttctctc ctttatgata aaaatttgtt atccagatgt
    14221 aatcatattc aatttttaac aaacttacaa gacagtgtta ttttatgtgt gtattctttt
    14281 atttaataca catcgttttt tcatattttt tccatcaaaa aaataagtta ttttctttta
    14341 tttcattgac cttattgaat ttcaagctat tttgaatttt ctgcaaaatt aaaaacatta
    14401 gttattttat aatcctatct attttcttta catttttcat taagaaaagg atataaaaaa
    14461 aagaggacgt tcattcgtcc tcttcattga tcaacgttta ttttttacat gcaagcttcg
    14521 catggcattc aaaacagcta atactgtcac cccaacatct gcaaatactg catctcccat
    14581 tgatgcaaaa ccaaaagcac ctaaggaaag taccaaaatt tttatcccaa tagcaaagac
    14641 aatgttctgt ttgacgattt tcaatgtttt ctttgctaaa tggattgctt ctgcaatctt
    14701 cgatggttga tcattcatga tgactacatc tgctgcttca attgcagcat cgcttcccaa
    14761 tccacccatt gcgattccta catctgctct tgctagcacc ggtgcatcgt tgattccatc
    14821 tccgacaaat gcggtctttt tattgttact ttgtaagatt tcctctaacc gctgcacttt
    14881 atcttctgga agcaattcgc tatatatctt gtccacgcct acttgcttcc cgatatgatc
    14941 agcaattttt ttcgagtcgc ccgtcaacat gactgtgttt ttcacaccag cctgttttaa
    15001 ttgaaccaat gcgtctacgg catcttcttt caaggtatct gcaataacaa gataaccact
    15061 gtaactttga tcgatcgcta gataaagcaa tgtaccgatt tcttgacttg aaggaaaaga
    15121 gatttcaaat ctttccatca atttgtgatt acctactaat acttgtttgc catcaacttc
    15181 agctaagatc ccttcacctg caaattcctg gatattagct gttggtaaaa gcggacctgc
    15241 gtagccttct aaaacagatt gagcaatcgg atgtgtagaa aactgttctg cacttgcaac
    15301 atattgcata aatttctttg gatcaattcc tgttggatcg atcgtctgga tcgaaaagtc
    15361 acctttcgtt aatgtgccag ttttatcgaa taccactgtc tcagtttgtg caagcaactc
    15421 caagtaattt gaacctttta ctaatacacc gattttactt gctcctccga taccgccaaa
    15481 gaaactaagt ggcacggaaa tcactaatgc acatggacat gagatcacta aaaatgtcaa
    15541 tgctcgatag atccattcag aaaacgccgc tctagaaaca acaagtggag gtaaaacagc
    15601 taataaaacg gccaatccta caacgactgg tgtgtaatag cgcgcgaatt tagtaatgaa
    15661 attttcagct ggtgcttttt tactgctggc attttctact aattctaata atttgctgat
    15721 agtagaattt tcataagatt tttctacttg aactaaaaat ggtttatttt tattgataaa
    15781 tccgcttaat actgtttcac caacatatac agatttaggg actgattctc ctgtaagtgc
    15841 tgacgtatcg actaatgatt ctccttcgat gatcgttcca tctaacggta cacgttcacc
    15901 aggcttcaca agtacaaact gaccgatcag cacgtcttca gggttcacgg tcatcaatcc
    15961 ttccgccgtc tgcacgtgag ctgtttctgg acggatcgcc atcaattcgc gaatcgattt
    16021 tcttgaatga ctgactgcca atccttggaa atactcgccg atttgataaa atagcatcac
    16081 tgctacggct tctggatatt caccgatcaa catagcgcca atcgtagcaa cagacataag
    16141 aaaattctca tcaaagattt ttcctttgac gatattcatc actgccttct tcactacatc
    16201 atatcctatc agcagataaa tcaataaata ccctatcaag cgaattggtt cattaaaatc
    16261 aaataatagc aataaagcga tacctgcaag ggaaaataaa atccggaaca gcgtatttct
    16321 ctttttttca tttccatgtt cagatacttt ttccttatct atttctgtta ctttgacatc
    16381 tggttctaat tccttcacta ctttttttgt ttcttgttca atcgtagcca aatgatcttc
    16441 ctctgcgtca atcgttagtt ttccagaagt gaagtttacc gttgcttcct tgactccatt
    16501 gattttctga actccttttt cgattttcat tgcacagttc gcacaatcta aaccttctaa
    16561 tctgtaactt ttcattttaa tgacctcctc gcctcaacat atgaatatct cttcataact
    16621 aattataaat gaatggttat tcatatgtca aggtatccga aagaaaaaat gaaaaacatc
    16681 tgcatcggaa aatttcttcc atacagatgt tttggcttat tctttctttt tctcttcgat
    16741 cattgccact gctcttatcc aacccgcact tgccttcttg atcttgacag gatagcaact
    16801 aagtttgaag cctgttgctg gcaatttgtc taaattcatt aatttttcga taggacaata
    16861 tcttttttca atccctgcaa aatgtccttc ccagatatac gaagctccac tacgctttca
    16921 aaaatataga aagagttctt taatgaaaat tatttcaact ttccataaac agtaacccca
    16981 tataaataaa agacgtaaaa gtcacataga agaacttata caggaaaacg catagagtca
    17041 ggtgaaatac atgtatccca cctggctcta tgctttatct aacctttatt attctctttt
    17101 atacaatttc tgcaccgaat ggcatcaacg ccaatcgagc aagtttgaaa gattgcttgg
    17161 caaaaggtat ccctatgatc gtgatacata gaaggatgcc gctgacgaca tgtgcgagag
    17221 caattggtag gcctgaaacg atcagccaga tgatattaac gatcaatgac atgccagact
    17281 ggtgataaat tacttctttg ccaaaaggcg caaaagaaag ggaggcgatc ttaaaacatt
    17341 gcataccgat tgggatacct atgatcgtga tacaccaaag tatccccgct gctaaccagc
    17401 taagaccacc gattagtccg ccgaatataa accagatgac atttcctaaa caactcattg
    17461 tatttctcct tctattactg tttttgatta aaactgggca aaaattgatt ttattcttct
    17521 ttttttagct tccagcatca agtattctgc aaattttttt tggatttctt ccgtattttc
    17581 ttttgttact aatgtgtgtt ggattagttt tcctgatggt cgctgatcca atcgttcttc
    17641 tgactgttgc acgtccgctt gcgcaaatcc gataatccgt ttttcttttg ttacagcaac
    17701 gagcaatagt ttattcttat catttaggtc agctgccgtt tttgctttta cgaatgattc
    17761 tggatgatca gtaatcagct gattgatttg aggtaaatct tcttttactg cccaccttat
    17821 ttccatcatt tttcactttt ctttcgctca tttttatctc cactaaaaaa atcgactgcg
    17881 acaattgcat ctatccagct ttgtgcaatg atctcatgtc cgccaatcgt tgggtggacc
    17941 ccatcttctc ttgtatattt cgaaaaacca taagcaatcc ctaaagcatt gaatatacca
    18001 tctaaaggaa ccagcaatgc gccatattcc ttagcaagtt tacgaacaat ttggatttta
    18061 gggtctaagt ctttacgcca gccatgacgg tcgtcggtta taggaagtac aaacggctcc
    18121 atcaagatga tgttgcagat ttccgctgtt tgaagttcat ttagtaattt tcgataaacg
    18181 gattcaaatt gctgagcaga tttctcagtt ccgaatatag cctgatcgct agtattatgc
    18241 caggtatcat tgattccgat caaaatcgat acatagtcag gttgtaaagc taaacaatct
    18301 tcttgccagc gtacttgcag atctgcaatt ttgtctcctc ctatcccacg gttcatgcat
    18361 tcaaattcca tcgttggata ttgggagatt agttttccgg caatcaaaag tggataacct
    18421 ttacctagat cagttgcttc tgctcggtat cttcctgcgt ctgtaatgct atcaccgata
    18481 aataatatac gttttttcat ttgtcaaaaa ctcctttttg aataaaacga tgattttctt
    18541 ccttatatta tcccataagc cctatcaaga cgaaagagaa aatatatgta taaaaaatga
    18601 caccagccta gttccttcaa acaattgaat gaacgctcat caagtgtcta gttttttatg
    18661 ctattttttt cttaacgtgc cggattcccc ttgattcctt cgttgtttgg tccagagaga
    18721 tcgatcacac ccaagcttcc gtcaatcaga ccactgatga cgccatcgaa acatatattt
    18781 ataggctcat ctaagacttc tagtaaatgt ccctttacta atatctcttc tagattgctt
    18841 gggatagatt ggtcataact ttatctggtc cgatgatttc aagggtgaat tgaacttaca
    18901 tatggattat tgcatgctga aaatacggac ctactccatc ttcgaatgtt actattagtt
    18961 tgttttcagg tgctagatgc tgctttattt caacagcaga agcatcatca aatcagattt
    19021 ccatttgaat taccttcttt gtaaatgttt gattgattgc gatttcgtta tagaaccttg
    19081 tgaatcaaat agcaatttct tttgctttct tctcttgtct gctggaaact tccattatcc
    19141 cgtatttaaa aaaaagaact gcgagagttc gcagttcttt tttttaaata aacgttgctc
    19201 tccggccaca agtcacaata gtcatcaaac atgaaaaact gttttttgaa attactcctt
    19261 gtgactcgga gctgaacggc aggcgcacaa cctcttatgg ataaattcgg ttcaacaaac
    19321 gtgggaatgg aatagcttca cgtacatggt cgataccagc aatccaagtg actgttcgtt
    19381 caagacctag accaaaacca gagtgcggaa cagaaccgta tttacgtaga tcaagatacc
    19441 atgaatattc tttttcatcc aaaccgtgat tacggatttg ttctagcaag aaatcatagt
    19501 ccgttgcccg ttcgcttccg ccaataattt caccgtaacc ttctggtgcg atcatatctg
    19561 cacaaattac cacgtcttct cttgttggat gtggtttcat gtagaatggc ttgatggctt
    19621 ttggatagtt taggataaag acaggctgtt cgaatgaatt cgcaatgaac gtttcatgag
    19681 gtgaaccaaa gtcttcgccc cattcgatgt catcaaatcc atttttcttc agtaattcga
    19741 ttgcatcatc gtaagtaata cgagggaatg gcaattttgt ataagttttt aagacttctt
    19801 tgtctcgtcc tagtacatct aatgcgtatt cgcaatgatc taaaacattt tgtactaaga
    19861 atgctacata ttgttcctgt acttctaaac tttcttcttg atgagtgaaa gccatttctg
    19921 gttcgatcat ccagaattcg atcaaatgac gtcgtgtttt tgatttttca gcacggaaag
    19981 tcggaccgaa tgaaaagact tttccgaaag ccatagcagc agcttccatg tataattggc
    20041 cactttgaga taaataagct ttttgatcaa agtaatttgt ttcgaataga tccgtagtgc
    20101 cttctggtgc agaaccagtc aagatcggcg gatcaatttt gacaaaatga tgttgattaa
    20161 agaattcata cgttgcacga atgatttcat ttctgatctg cataatcgca tgttgtcttg
    20221 aagaacgcag ccataaatga cgatgatcca tcaagaagtc tgttccgtgt tcttttggtg
    20281 tgatcggata atcgtggctc tcgcttacca cttccacatt tgtaattccg atttcataac
    20341 caaattttga acgactgtct tcacggattt ctccagttac taacacggat gtttcttggt
    20401 gtagattttt agctgtttgg aaaacttctt ccgacacttc gctttttaca actacacctt
    20461 ggaaaaaggc tgttccgtct cttaattgta aaaatgtgat ttttccgctt gatcgcttat
    20521 ttgcgaccca agcgccgatt gttactgttt ctcccacatg gtttttcgaa tcgatgattt
    20581 gaatttgttc cacgtatgac tctcctttta tattccttga atttcttcag gattaatttt
    20641 gacttttact ctcaataaat tgcttgattc tgcgtaccgc ttcttctaac gtagcgcgat
    20701 cagtagcata actcatgcgg acattttctg gtgccccaaa gccttcgcca gtcacaagcg
    20761 ctacccctgt ttcttctaaa agatcttcta cccattgtgt gacattttca tatttacaca
    20821 tgcgtagcgt ttcttttaca ttaggaaaaa gatagaaagc tccttgcggc ttttcaagag
    20881 aaacacctgg cagttctgcc acaagcggat ataacgtatt caggcgttct tcaaaggcgt
    20941 tccgcatttc ttctactgta tcttgctcac ctttcaatgc ttcaacagct gcatattgac
    21001 tgactgctgt cggattactg gttgactggg aagcaacagc aatcattcca ttgatgatct
    21061 cagaattccc caccgcataa ccaatgcgcc agcctgtcat cgcatatgtt ttagacacgc
    21121 cattgatgat gatggtctga tttttgattg cttctgaaat cgttgcaatt ggagtaaact
    21181 cattgccatt ataaactaaa cgaccataaa tatcatcagc aactatcaaa atatcatttt
    21241 ttactgccca ttcaccgatt gcctgaagtt cattcttgct ataaatcatt ccagtcggat
    21301 tcgatggaga attgatgatt acggcttttg ttttttctga acgtgcttgt tctagctgtt
    21361 caacagtaac tttccagcta ttggattctt cccctttcac aaagacagga agtccttctg
    21421 ccagttttac ttgctcaccg taactgaccc agtaaggcac aggaatgatg acttcatctt
    21481 gcgggtcaag gatcgtttgg aaaagggtat acaaagcaaa tttcgctccg tctgttacga
    21541 ctgtttgtga aggttcatag acaagtccat agtttttctt cagataatca acgattgcct
    21601 gtcgaagctc tgggattcct gctgttggtg tataatagct agctttccca ttgcggattg
    21661 cttcgattgc tgcttcttgg atgttttctg gtgtcgcaaa atccggttct cccacagtca
    21721 aactcagcac atctctgcct tttgctttta atgccttggc ctttgccgca gctgccaaag
    21781 tgacagacgg ttctaatcgt tttgttcttt ttgataactc catcccattc attcctttac
    21841 cttttaaatt cccttgattg tcttgacttc atctccagat tcaaagccaa tcaggtaata
    21901 attcagtttc ccatttgttt cttttcctac tacttcccac acaggctgat catcatacat
    21961 ccctaaagca gctttttcga tttggatttc aggatgggcc gcagcaattg tctgttttgc
    22021 ttcgttttca gtcagtccct ttgtttgatc caatactttt actttttcac cagatttagg
    22081 aatgataacg gcgatttctt ttcctttatc atttgtacct gtcagtgaaa agtatgtctt
    22141 ctttcgagta aaccaataaa aatgatcggt ttcctcaaga tttgcatatt tctttgcgat
    22201 ttctactgct tctttcttcg cctgcaccgc cggacgactg gaacgcaagt aaaaaatcga
    22261 gctgatcacg atgaccgcta ataaaaatac gatcaagcca agtaacacgc gattaatcgt
    22321 tttttccttt gtctgttttt tcttcaaggg tcgtcgctcc tttatcttca ttccttttca
    22381 ttatagcaga ttttaattat gaaaaaagac agctcctcta acttccttct tcatttttct
    22441 ttaagaattc atggatatcc tgatagattt cctccatagc tagctctttg atcggtactt
    22501 ttttcggtaa tgcatggatg atccgtgcgc catattttgc agtgactagt cttcgatcca
    22561 aaataagcaa tacgccacga tctgtctccg tccttatcaa gcgacctaat gcttggcgta
    22621 acttcaaagc tgctttaggt acggattcct ggtaaaaagg attgatcccc tctgattcta
    22681 aataagcgtt cctagctttg accatcgggc gaagcggatt atcgaagggt aaacgtgtga
    22741 ctacaacgat ctgcaaagca tctccaggca aatctacacc ttcccaaaag ctgtcagcgc
    22801 caaacaatac gcttttttct gacaaaatga agcgtttcaa aagcttctcc cggcttccac
    22861 caaacccttg agctagtatt tctcgtcctt tttctagcat agacagatgc attttctgat
    22921 agaccttctg caaaacatca tgagaagtga ataacacaag tattggccga tcttcttgtt
    22981 cgatcagacc tgtaagtgct gtctctaaat aatcgatgta tgcttgattg ctgacttgat
    23041 ggacggcagg tgcctctttt ggcacataga tccttgcctg tttctcataa tcataaggag
    23101 aggcaatcac tttaagaggt gctgcttcaa tgccaagcct cttagagaga tagtgtcgat
    23161 tagggccgat cttcagcgtt cctccaatat aaagaatacg atcatatcga ggataccaaa
    23221 cagtcgacgg caacatagcc gcttggaaat catggagatg aaaaatcatc tgctgcgctg
    23281 tgttcccagg aacgaaccaa tggatcaaat gatctcgcca gtcttccagc cattgatcca
    23341 tcagcaagta ctgcttgtct aattgatcaa ataagctata taaacttgct aaatcgatcc
    23401 gcatctggtt tgtccagctt tcttggataa tctcaaaagt cagacgcatt tgtgactgta
    23461 gctgctgaat ctcctgataa aaaagctgca ggtgatcaat ggctgtccca gattccagtg
    23521 gcagctgatc cagcatctct tttgtcatca tgacttcttc tggatactgt ccgttgggtt
    23581 gcttgccgct cactaaactc attaatcctt ctgccataca aatctgtgct tcgcatagcg
    23641 cagaaagttc ttctcgataa atcgataacc agcgtaaggc ttcatgttct ttcggtaaat
    23701 agctttgtat tcggtcaaac agctgatttg gttcttctaa ttgctggatt tgtttatgga
    23761 aatagttaat acttaatcgt ttgtcattta ctttttcagc gatttccggc aaatgatgta
    23821 cttcatcgat caacaaaaat ggactagctg gaagcaatgg ttcttttcgc tgtgtttctt
    23881 gtactaaaaa cgcatgattg acaatcaaaa aattactttg cctgattttc ttttgcaaga
    23941 aacgaacaaa gtcttgttcg taaaacgact gatttcttgc taaaaaccca gtacctctgt
    24001 gcgcgatatc tgcaaagaat gcatggttca agtttgttaa atgtaattca tccaaatcac
    24061 cggtcttcgt ttgcgtcagc caaactaaga ccgccatttg atacaaagca tattgttttt
    24121 gttctggtgg ttccacaagt gttcctttaa atcgttgcag gtcgatatag tggcgataac
    24181 ttttgataat tacaggttgt atgggctgat ctagcaattg attcagcaat ggaatttctt
    24241 tttctatgat ctgctgctgc aaaactagcg aaacggtact gatgacagcg ggtttttcag
    24301 gtgtagccaa ataactcaat ggcaacagat aaccgattgt tttacccatt cctgtagctg
    24361 cttcgatcat caaatctttt gattcatctt ttgtgaaatg gtcgtagatc gcattcatca
    24421 gtctgttctg ttcttttcga tacatcagtg ttttaccaaa catcttttct tttgcttgtt
    24481 tttttcttgg atatgtccgc tcgccgtaat ggacggatgt gaatagttcc acttcttttt
    24541 tctgcaaagc tagcccatcg acgatttcta atgaggaatc aagtggctct ggtttttctt
    24601 tcatttcttc aatcacatga taaatgaaac gactcgtatc catacctgtg tgtctactta
    24661 atcgcgcaat ctgctctaac gtgatgattg gcaattttct catccgttct tcgatcagca
    24721 aaagaagttg acctgtcact tcggcatcac tatctgcctg atgaggattc tcatgaataa
    24781 atccaaggct ttctgacaaa tcagctaagc gaaagcttgg ttccgtcggc aagaaaattt
    24841 gtgcaagttc tactgtatcg atgcctggta tcttcaaact aggaagtccg catcgcatga
    24901 gttcatggtt caaaaaatta taatcaaaat aaatattatg cgcgacaaat atggtgtctg
    24961 ccaaaagatt gtaaatcgtt tgggcgacat cttcgaaata aggcgctttt tggacgcgtt
    25021 gattcgtgat ccctgttaaa tgctggattt gttttgaaat cttccgccct ggatgaatat
    25081 cgatcgaaaa acgtgaagtg atccgacctg attcaatcat gacgcagcca aattggatga
    25141 tccgatcttc ttttggattc gtcccagtcg tttcgatatc aacgactgca taagttcttg
    25201 gtttcaaaat atcttcctct tctcctgcct ctaatgttct tttgaaatta tactacaaag
    25261 tgcagaaaaa tactctcatc gctttttaaa gaaaatagac aaaaacgccc agacacgcaa
    25321 atgtctgggc gtttattttt tagtataggt taattaagct ttagtaacgt ttgttgcttg
    25381 aggtccgcgt tggccttctt caacatcgaa agttactgct tggccttctt ctaaagtttt
    25441 gaatccgtcg ccttggatag ctgagaaatg aacgaataca tcgtttccgt tttctgcagt
    25501 gatgaatcca aatccttttt ctgagttaaa ccattttact gtacctgttt ccataataaa
    25561 aatcctcctt gtgtatcaac acatattttg caattacttg aatggtgtat atctggaaga
    25621 tgtttatttg aaacaagcta ccacagatta ccgaacaaaa actactccta tagtatatca
    25681 taccgtttac aaaaaagcta gagtttttcg acttttttta ttaaaaaaag ttttctcagc
    25741 gattacataa agtgaaaaaa cgaacttttt ttaaaataaa cgacatattg ttcagttggt
    25801 gtttttttgc tctgatgttc ttctttaaac taaaaaaatt attctttctg actacttatc
    25861 ggttctgttt caacggtcga ggctggggaa gattctttag taggtctgat gttctcatgg
    25921 tatttctgat agcctatgac agtgaccaga agaacaaggc aaaccaatac gatcaacgag
    25981 attagttttt cttttttgct catatctata cctcataaat aacaggatga tgtccatcat
    26041 atttctgagt atgagtaaaa gcaaaagctg cagctgtaga atgtaagaaa tgccagcaac
    26101 tttcataatc acaggtcgga cagtaccaaa agtaaccaaa tcttggctgc aaagaccgtt
    26161 cttctgtttc aggaatcgca gaatcaagat ctgttgtctg tacataaaca tttttgtaca
    26221 gacgtgtgcc tgtaatagga gaccgctgtg tttcttcagc aaaaactggc tgacttgtta
    26281 aacttaggga tagaaacagc aaacaccata acagtctttt tttcataaag acctccttat
    26341 cgataagttt ttcccaatta aaatcatatc tcaagaacgc ccgttattca cattttgttc
    26401 ataaatgatg ttttttgtat cataatcgtc aaaaagaggt cgtgaccacg tcacaacctc
    26461 ttttttaaac ggtgttccag aagtagcttc ttcggaaata agccgaaatt tcacaaaaat
    26521 ttgagaaata atttttgtca atctcttctt atttcttgaa gctgaccact tctgtcacaa
    26581 cctcttcctt aatactcagg tcaaaacact gatttcacaa cctcttttaa taacgaagaa
    26641 tcgctgtcag actcttttca tctggcgcat ctttttgatc caaaataaac actttcccgc
    26701 cattaatgat cacatcatct gctaatgcat tcaacacttg acgccgatca tattctgttt
    26761 caggatcttc accgaaacca tcagctaagt ttgacgtagc gataaataaa tgtgacactt
    26821 ttccttcttt cgcagctgga acgatatcaa ctaactgatc gatgaatttc ttatctaaga
    26881 gtttattgta ttcttttgat tcttgagctg cgagttcact tgacagcttc ttcgcccctt
    26941 cttcgatatc tctaaaggat agctgcgcag gagaagcaga aatcgcaacg tctgcacaat
    27001 aatagggatt tttagcaatt tttttgaaca tcgtctgatt ttctggtaat gcaaataaat
    27061 aaatcggcca ttgttcagga ttttcgaaag aatcctttaa gtacgtatca acagcttggt
    27121 aatagttgac ccaatcgatc tctacttctt catcttttgg atttacgcca tggaaagtta
    27181 ctccatctcg ggctccgcct cctccattag aagagaagtt caaaccgcca cctgtcagtt
    27241 cagatcccaa tgcagtaacg acatcaaccg gtgccccttc tggtagagat acttctttta
    27301 cttgtttgtt gctgacctca tacaatttca tggagtcgcg gttcaatccc aataaataat
    27361 aagaatagtt gaactgccca tttttgataa tagccagtaa ataaggaaga tcacttacat
    27421 agtattgatc gtctaccggg atactcaaac gatggatata ggtctggtca gcagttataa
    27481 tgaccgctac actcgtagtt gcactacgcc aaaacgaagg atctcctaac aaattttcaa
    27541 ttttttcttg gaacggagac cagtcatgtt cggaatattt tttctcaaaa cgtttctttg
    27601 cttctttcgc aaaatttttg aatttgatct gatctttttc cacatcttga tgggcgacat
    27661 gcgtattcag catgatcgtg acgaatggtc ctttagcgcc ttctgaagtc aattgtgtca
    27721 ataattcttt atcctttttt gccataaacg tacccctcct aaaaaaatca ttcctttgtt
    27781 tctatctaaa gtctaccaca acactatttt tccatacaat aaaacgtatc taaaaaaata
    27841 aaacggtttc tacggtttta aatttagcta tttttttaag ttatcttcat aatttcctca
    27901 attatttagc cccagtcttc aactattctt catgaaatgc tgataaacta agaaaaagaa
    27961 taaaagaggt ggatcttatg catttaatta tgattttcag tttattaagt attatcagtt
    28021 tatttgcttt cagcgcttcc cgcttattag atgcggaaac acggcctatt cctgtaaaag
    28081 tacgtaaaaa cgaccgctaa acttccataa cgcgcgttct tatcctaaag ttttttcaga
    28141 aacattgaaa ctctctcccc tctctgataa aattttaatt tgtagcgaaa caaattaatt
    28201 acaaggagat cggatatgtc cataaaaaaa acacgtctag tcctattatt ggctagtctc
    28261 attctttgcc ttgcttcttt tctaccagct gttgctgtgc aagctgaaga tacgttcaaa
    28321 gtaaatgcaa aagcagcttt tgctgtagat gcgcaaagcg gtaagattct ttatgatcaa
    28381 gatggagaaa aaaccatggg gatcgcttca atcacaaaaa tcatcggtct ttacatcgtc
    28441 cttgatcaag taaaagaagg aaaactgtca tgggatgata aagtttcgat ttcagattat
    28501 gcagaaaatt tgagtatcac cccagattta tcgaatgttc ctttgcataa agaaaacacc
    28561 tacactgtca aagaattatt cgactctgca atcatccagt cagccaatgc ttcaatggtg
    28621 gccttggcag aaaaaatctc tggcagcgaa gctaaattca ctgaacgaat gaaagaacaa
    28681 ttgaaagatt ggggaatcaa agatgcaaca atcgttaatg catcaggatt gaacaactct
    28741 tatcttggcg aaaaccgacc agaaggcact ggagaaaacg acgaaaatca aatgtctgct
    28801 caagatgtgg ccatcgttgc ccgccatttg atcttggatt tcccagaaat actggatgta
    28861 tcaagtacta cgacccaaat gtttggcgaa aatacgcaat caccagtgga aatggtcaac
    28921 tggaactgga tgctcccagg attcgttaat tacaaggaag gcgtggacgg attaaaaact
    28981 ggtacgactg agcttgcagg tgcttgtttc gttggtacga tcactaaaaa cgatcaacgg
    29041 atcatcactg tcgtattgaa tgcggacggc catgcggaaa acccgagtgc ccgcttcaat
    29101 gaaacagacc gtttgatgga ctactgctat gacaattggt cagaaaaaga gctcggaaaa
    29161 gctaacgcaa gtattcctag tctaaaaacc attgatgtaa aagacggaaa agaatcaaca
    29221 gttcctgttg tgcttaaaag ccctgtaaaa gtatgggtac gaaacgatat ggatactggc
    29281 aaattaacga tcacgccaac acttgacaag aagcaagtca ctgacaatga gatccaagca
    29341 cctatggata aaggtacaaa aatcggtacc gctacgatca ccttggcaga cgataaatta
    29401 ggctatttag aagacaacaa tgcaccatca acagagatca ttacggataa aacagtggaa
    29461 aaagcgaata tattcgtgat tggctggcga cgcgtcgcag aatttttcga caacttgttt
    29521 taattgaaca ataagaaaaa catctttcca tcggaaagat gtttttttgc tttttctagt
    29581 ttaaataaca gcttttttca tctattttcg ttatactgta taagaaaaag gagttgaatt
    29641 tatgaatcta accagagatc tgatcttttt agttctctat cttattgggg tattctctat
    29701 cgtttattgg cgaaaacaga agaaggatcc ttccttgttc ttttacggca gtacgtggac
    29761 atttacggta atcttaactt attttgtcgt gttggaaatt ttttattcga ccttttattt
    29821 tttgattcca ttgttgttct ttagtatctt tgctttttct tatttcacag aaaaacgaag
    29881 gctgctgaat ggtcttttat tcaatgtttt cctcatcagt ttcggcatct acttgtttgt
    29941 cttgctgtat gaaacgcaaa atattttcct tggcggactg atcgccttga tcacgattcc
    30001 attgctactt gtccttttat ttggtattta tggattgatt gtttttcttt tttggaacgg
    30061 ggtcacagtt ttacgtagag aatcgcattc attagctaat cttttaacgt tgatactagc
    30121 catttttctt acactgtttc ttgtttttga ctttttcttg ttaaaatatt tgccgcaatg
    30181 gataaatgct ttgtttttct gcgttcccct gatcttgatc tatctattta tcgtattcta
    30241 caactttttg actgtctcat tcttgtatca gttcaaccgg cctcgataca atcaagactt
    30301 catcgttgtg ttaggcgctg ggttgatcaa tggagaaaca gtttctcctc ttctagccaa
    30361 gcgaatcaat aaggcaattg ctttttatcg ggctcaaagc cgtgctacat taaatccgcc
    30421 catcttattg atgtctggcg ggcaaggagc agacgaaaaa gtaccagagg ccattgcgat
    30481 gaaacaatat gccatggaac aaggaatccc tgaaagagac attcttgtcg aaaccaattc
    30541 gacaaccact ttggagaaca tgctctattc aaaggaaatc atggatcagc aaatgaaagg
    30601 gccataccgc gcgatcttta gttccaacaa ttaccacatt tttagagccg gtctttatgc
    30661 gtggcaagcc aaattgaaag caaatggtat tggtgcaaaa acagctttct actacttgcc
    30721 taatgcgttt ttaagagaat acatcgccat cttgatgatg aacaaaaaaa gacatatgat
    30781 catttgcgga ttgcttttcg caggctccgc attcttatcg ctgattactt tacttttcta
    30841 aaaaaacaag gtgtgacaaa acatatgtca caccttgttt ttttctttca ttctcttaac
    30901 tattggcaaa aagagtatcc cttttttgac cgctacttgc tgggcagaat aaataccgct
    30961 gttgcctgaa cacataaagc tgatcaagca gatcataaag aagtatactg ccgcttgtga
    31021 accgaacaat tcgatcccca tcacaaagca ggcaatcggt gtatttgtcg caccagaaaa
    31081 tactccgata aagcccaatc ctgcaagaaa aggaacagaa acatgaagca aaggcgctag
    31141 tgctgcacca agcgttgcac caatttcaaa caatggtgtc acttctcccc cttgatatcc
    31201 cgcgcctaaa gacaaaactg tgaagaataa cttcccaata aaatcataga catgtgcctg
    31261 tccattaaat gattcttgaa gtaacggaag actcaatccg agataacgtt gtgtttgcaa
    31321 aatcaatgct gctgccacaa ctacagctcc acctatcgta tttcgccaaa caggatgagg
    31381 aatccattgt gcatatcgcg cttttaaaaa gacgatcgaa cggctgaata cccaaccaat
    31441 caaaccaaaa gcaatcccag caacaaaaac tttgaagaac agcaacatac tccattcagg
    31501 aatcacaccc atttggtaat gtagatgaga aacaccatag ctttctgtca tgaaatttgc
    31561 aaacagtgca gcaaagaagc tagggaagat cgcttctgtt cggactttcc cgattgccaa
    31621 cacttctaat ccaaataatg ttccagctaa aggtgtgcca aatacagaac taaaacccgc
    31681 actgattcca ctgataatca agatttcccg ttctgcttta tccaatcgga acaaacgtgc
    31741 tgtattatct gctaacgatc cccccatttg gactgctgtt ccttcacggc caacagaccc
    31801 cccaaataaa tgggtagtta tggttccaaa cagtgtaagt gtaataagcc gcaacgggat
    31861 tttttcttct ccaccatttc cttgatcgat cactaagttg tttccacgac tagaaagacc
    31921 gccgtgatac gcatagagat aagcaaaaag cgcaccacta actggtagta gataaaggag
    31981 ccaaggatgt gatagtcgga tatctgtcac aactgtcagg ctatttaaga aaaaagcaga
    32041 caagctcccc atgaatatac cgagaatcgc tgtgatcacc agccacttca gcatgtacac
    32101 taaaatgcgc attggactcg gtaattgttt ttccataaaa aattcctcct caataaaaaa
    32161 acgcctacta aagaaagggg ctgtccccag actttagtag gcgtcattag ctatctttcg
    32221 ttagcattta aaggcgaaca ccatcaccta ttcacttcca ttaaaagata gcatattttt
    32281 ctgtaaaaaa caataaaatt atcgttcttt ctttacacgt tcagcaaatt catagaaagg
    32341 agccaatttc gttaactgtt gattacattg gtcactatca tgacaaatat aattcccctt
    32401 tttcgtatac gtgccatcag aacctgcttt cgttgtagaa agaaaaagcg acacattcga
    32461 tgttttctga cagattgcac agattccctt atttatcgtt ggtgataaag taccgctaat
    32521 cccttttaat ttttcatctt cgtaatagac catgaatttt ttctgcgtac ctggatcatt
    32581 ccagccgatg tacgtatgtt cttgcaagtc gatttcattc caagctggtt gtttgagttt
    32641 ttttactttt cggaataatt tctcgatttg tggtttgcta ggctgcataa acggctgaac
    32701 gatttgcttc agcttctcca atgctctttc tgcttgcgct tttgtcagtt ttacgtctaa
    32761 aactgtcgtt aaaaatgtat cgatttctgg cagttcgtga tttaatatgt ctcgaatctt
    32821 ttcagctgct agtgcctgaa ctgtttgtac cgtttttgga tcattgacag atgagtacgc
    32881 atttaataac tgttctactt ctctttttat aaaaaaatat tggtatggtt ttattgtttg
    32941 ttccatgatt ttaaagtcct ttcttctaac caaagtgcat actttgtaga aaaaagtgat
    33001 cttctgcaaa gtatgtgtta cctgaagatc ccggactctt ttaaataaga tacgttttgc
    33061 atcttatcat cacccccttt aatgcttatt cttctatgta catgattcat tcgataaata
    33121 aaagtaaacc gtatcttgaa cagatagtca actgcaaaca gaaaaaagga ctgtgacaaa
    33181 agtcgtgtca aagtcccttg tttcgaatga atggtgttca aaagcttgca tctgcggtaa
    33241 taagccgaaa cttcacaaaa atttgagaag caattttcgt aaattccttc ttatttcttg
    33301 aagctgacca cttctgtcac aacctcaata tggtctatta ttggttttac ctgttaaatc
    33361 gaggattctt tcccaaagta acgttgccat ctcttacgca tacttgcaga catgggctga
    33421 gccgcttctt tgactgcgca gtatttgtcc acgaatgtca caatatatcc ttctttatac
    33481 ttaggcggtg cgatcgttgc accccacatg tgcttcaaaa tgatatctcg ctcaagatcc
    33541 gacaaatcgg tgattttttc tgcattcttt acagcaattc ttggatggat atacgcatgt
    33601 gtcccctcgt caaatttcgt cgtacgccaa tcatagtaga acagatcatg caaaagtcca
    33661 gcacgcgctg ttgctttagc attgccaccc catttttttg cgagcagata actatagtaa
    33721 gaaacactga tggaatgctc caaacgagtg gaatgaacat gctgtgtgta attcgctaat
    33781 tttttcactg cttctgtttc taaaagatct tgtacataag acatatattc ttcgtcttca
    33841 cgccattttt ctgtcataat tatcgatctg ccaccttttt gaatttcatt ttcttctgaa
    33901 attgatctaa gtataccacc agtgttcgga ttattctagt cgctctagat aaaatagcta
    33961 aagcttaata gttccttaat cataaagaaa aatgataaag aacgatccct gctgcgactc
    34021 cgacattcaa tgattccgca tttcctttca ttgggatata tacgttctga tcagccgaag
    34081 acaagatttc ctgacttact ccctgacctt cgtttcccat gattatagcg aaatcctctg
    34141 ttttttctac tttgtctaat gcatgtgctt cttcatttaa ttctgtaccg tacaccgtaa
    34201 accctttgcc tttcattaca gggatcactt ctgccaaatc tttttgtaac acaggcaaat
    34261 gataattgct tccctgcatg cttcgcagca cctttgtact ataaatatct gccgttcctt
    34321 tacctaataa aacaccagcc ataccaaacg catctgccgt acggatcatc gttcccacat
    34381 ttccaggatc ctgtacatta tctagtaaaa gccagcctcc tgaaaaatct ggcgtatctt
    34441 cagatgttaa cgtcatcact gctaagatcc cttgcggtgt aggtagatct gacatagcgg
    34501 tcatgacctc atctgaaact agaaaagtag aaatctcttt gtttacagcc agccagtctc
    34561 cccattcttt catacctctc tgtgtcacaa aaagttcttt tatttctgca tcagacgacg
    34621 cagcttcttc gatcagatgg aacccttcca aaagatattc tgccttttct tctctgtatt
    34681 tctttttatg tagttttttt aattctttga ttcttggatt ttttactgat tggatctctt
    34741 tcacattcct cacctcaact gattatatca tggaataggt gcttgagctt gtttcatcct
    34801 aaaaaaatcg gtatcattga tttataaaac aggaaagaaa ggtgacgaac atgcgcaaag
    34861 ttaaaatgaa tgtccaagga cgtgtccagg gcgtgggatt tcgctatatg accaagatgg
    34921 ttgctgatca gttaggcgtg accggaacgg taaaaaacga agacgacggc tcagtcacaa
    34981 tcgaagcaat cggaaatgac gacatcatcc aaaaatttat cgaagaagtc aagaagtctc
    35041 cgagcccaag tggacgagtg cagtatgtgg atgtccaaga agatccgatg attgaggaac
    35101 gaaagaaatt tgatgtggtg ggataaggtt gtttttgaag cgctttgcct cgagtattaa
    35161 ggagaaacat tttccaaata gcttctcata ttttgaaatg taatgactta ataccgagag
    35221 gcagctgata aaacaccgtc aataaggttg tgaaaaagct ggtctgcatc aagcattaag
    35281 gactggttgt gaaaaatagc tctccatatt tttcaacagg ctggacttaa tgccgtagat
    35341 gcaagctttt gaacaccgtc gataaggttg cgaaaaagct gatctgcatc aagcattaag
    35401 gactagttgt gaaaaagtcg cttagttttg agtattaagg aaaattttgt gaaaatggct
    35461 ttccacattt ttgcataaat ttgacttaat accaagaaac tgacttttga acatcgtcga
    35521 taaggttgtt tttgaggcac tttgcctcaa gtattaaaga caggtagtaa aaaagctgat
    35581 ctataacttg caataaattt gcttaaccca tattttccag acagaacaaa aaagttttta
    35641 gttttttaaa taagaaagaa acacttggaa tcactctttt ctttctaagt atttctttct
    35701 tgattttttg tcttttttca aaatttttcg ctacgaaaaa gaacgaatat ttatatgaaa
    35761 tttctatgaa gttgattgaa ttccatgcgc ttttttagta tagttaagtt tgtgtaaaaa
    35821 ttatagaaga ggaagtattc tatgaataaa tggaaaaact ggttattggg atccggactt
    35881 gtcagtatcc tgctcttttt atctggctgt gtgcggatgg attcaaacgg aaaccctgac
    35941 acttcaggaa tcgtttatcg agtactcgtc catcctatgg gccaagcgat tacatatcta
    36001 gttgagaatt tcaattggtc ttacggctgg gcagttattg caatgactgt gatcgttcgt
    36061 atcatcatct tgccactagg tatcagtcaa tcgaaaaaaa caatgatcca atctgaaaaa
    36121 atgcaagcgt taaaaccaca agttgaagca gcacaacaaa agctaaaagc tgcaacaaca
    36181 cgtgaagaac aaatggcagc acaagcagaa atgcagcaag tatatcgcga aaatggattg
    36241 agtatgaccg gcggaatcgg ctgtctgcct ctattgatcc aaatgccgat cttctctgcc
    36301 ttgtatttta cggctcgcta cacagaaggt atccgtgaat catcttttta cggcatcgat
    36361 ctaggctcac caagtatggt gcttgtggcc atcgcagggg tcgcttatct gcttcaagga
    36421 tatatttcaa caatcggtat tcctgaagaa cagaaaaaga cgatgcgtac gatgctgatc
    36481 gtctctcctg ctatgatcgt cttcatgtcg atcagtgcgc cagccggtgt tacactttac
    36541 tgggtagtcg gtggtgtgtt cagctgtctg caaacattca tcacaaacgt tataatgaaa
    36601 ccgcgtttga aagcacaagt ggcagaagag ttgaaacaaa acccgccaaa acaagtcgtt
    36661 actccaagaa aagacgtgac agaatcagca aagccagctg acaacaaaca agcaacaaaa
    36721 caaatcaaac aaccaaaaaa cagtacaaac aacaaaggcc gcaacgcagg aaagcagcag
    36781 aagcggaaat aaaaatatat gacaaaaaac tgtagacaaa taaaaaaatt tctttgttct
    36841 acagtttttt tgt
//
LOCUS       DAFEEZ010000022        35723 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000022
VERSION     DAFEEZ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35723
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.022"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..189
                     /locus_tag="LP245_001197"
     CDS             <1..189
                     /locus_tag="LP245_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1519127.1"
                     /translation="NSNGILRRNGLPKSMDFREVNQTFISSVSNQRNYIPRKSLNYRT
                     PIEIFLSYVQEAFYSSLI"
     gene            326..1264
                     /locus_tag="LP245_001198"
     CDS             326..1264
                     /locus_tag="LP245_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBL1519128.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            1279..2109
                     /locus_tag="LP245_001199"
     CDS             1279..2109
                     /locus_tag="LP245_001199"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBL1519129.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLVLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLLVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            2153..3178
                     /locus_tag="LP245_001200"
     CDS             2153..3178
                     /locus_tag="LP245_001200"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBL1519130.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHHLPDSIRAFTDMEDAVKDADAVLFVIPTKAIRSVAKELVAKLNTKPVI
                     IHASKGLEQGTHKRISEILLEEIPTEKRKAVAVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNHYFRIYTNPDVVGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            3193..4131
                     /gene="galU"
                     /locus_tag="LP245_001201"
     CDS             3193..4131
                     /gene="galU"
                     /locus_tag="LP245_001201"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBL1519131.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKIELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            4257..4697
                     /locus_tag="LP245_001202"
     CDS             4257..4697
                     /locus_tag="LP245_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBL1519132.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIIRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            4700..5302
                     /locus_tag="LP245_001203"
     CDS             4700..5302
                     /locus_tag="LP245_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBL1519133.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSAELTGIAKEKAQDLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(5364..6467)
                     /locus_tag="LP245_001204"
     CDS             complement(5364..6467)
                     /locus_tag="LP245_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBL1519134.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGADSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVVWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            6677..7678
                     /gene="ccpA"
                     /locus_tag="LP245_001205"
     CDS             6677..7678
                     /gene="ccpA"
                     /locus_tag="LP245_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBL1519135.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            8032..8427
                     /locus_tag="LP245_001206"
     CDS             8032..8427
                     /locus_tag="LP245_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519136.1"
                     /translation="MPKKRRKTIVIILTILAIGIGGKFYMDKREAQRQKDLLAVEKQS
                     VKVLKNTFADIREVKVEEFKKNPVTGCYGALVTMTNNEGKSVYFDYFFSKQMNEISSY
                     GVENEEIQNEGVTTPKIRVIYSNGEAEEV"
     gene            8424..8678
                     /locus_tag="LP245_001207"
     CDS             8424..8678
                     /locus_tag="LP245_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519137.1"
                     /translation="MTVKDEEYRYISEHVYWLDPKHPQYSKSYKEGAIKNFGETKFQI
                     LKIKDSLDGMQAMAAAPIVHSKLEKNFKNKKIPTNFRVLK"
     gene            8721..9116
                     /locus_tag="LP245_001208"
     CDS             8721..9116
                     /locus_tag="LP245_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519138.1"
                     /translation="MSRKIRKLSLAILLIVILGIGGKVYMDKREAQRQKDLLAVEKQS
                     VKVLKNTFADIKEVKIEKSARNEMTGAYRMFVTMINNHDESVYFTFGFWKERNELGDY
                     GVENKSIQKEGITVNKIRVIFSNNKEEYI"
     gene            9116..10171
                     /locus_tag="LP245_001209"
     CDS             9116..10171
                     /locus_tag="LP245_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HBL1519139.1"
                     /translation="MMADKQYSVISEAVYWLDPKHRDYDHTYKENSIKKIDSYNFKIL
                     KIKDSLDGMQAMGVAPIKNGKVDLSQVVIAFAGTNLSDWKDLETDARSIMNLYGNRPG
                     ASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALYV
                     AAEKQWKNVGLNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEVR
                     ISMETAFLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQEL
                     NNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSAKMKSAMEEVIRINQRGIFELEK
                     KWHGKKACGKHVLSPLR"
     gene            10168..10374
                     /locus_tag="LP245_001210"
     CDS             10168..10374
                     /locus_tag="LP245_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519140.1"
                     /translation="MTEQEIIEALASVVATKENLVDSAKEVYLLRINKARRMGEAFDT
                     LVKEIQDKINEIVTRDRELAQQFN"
     gene            10386..10709
                     /locus_tag="LP245_001211"
     CDS             10386..10709
                     /locus_tag="LP245_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519141.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            10702..10968
                     /locus_tag="LP245_001212"
     CDS             10702..10968
                     /locus_tag="LP245_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519142.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQIWAEKRLTDQNHQ
                     MTAEEAAQEFSNRHVHLKESVKGQFAEKLTELFQRQEKKLKQFR"
     gene            complement(11131..13476)
                     /locus_tag="LP245_001213"
     CDS             complement(11131..13476)
                     /locus_tag="LP245_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBL1519143.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKVIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            13755..14657
                     /locus_tag="LP245_001214"
     CDS             13755..14657
                     /locus_tag="LP245_001214"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBL1519144.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEGGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQAFDPEVFPELLAEEVTL"
     gene            14868..16643
                     /locus_tag="LP245_001215"
     CDS             14868..16643
                     /locus_tag="LP245_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBL1519145.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     ILASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSRRKLLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(16953..18539)
                     /locus_tag="LP245_001216"
     CDS             complement(16953..18539)
                     /locus_tag="LP245_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBL1519146.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            18790..19014
                     /locus_tag="LP245_001217"
     CDS             18790..19014
                     /locus_tag="LP245_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBL1519147.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            19156..20907
                     /locus_tag="LP245_001218"
     CDS             19156..20907
                     /locus_tag="LP245_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1519148.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFVIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            20907..22691
                     /locus_tag="LP245_001219"
     CDS             20907..22691
                     /locus_tag="LP245_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519149.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEKYAPQQNPGADQTITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            23148..23999
                     /locus_tag="LP245_001220"
     CDS             23148..23999
                     /locus_tag="LP245_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1519150.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSEQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGEKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            24095..25981
                     /locus_tag="LP245_001221"
     CDS             24095..25981
                     /locus_tag="LP245_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1519151.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIRAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILMMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGNLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEADETDDRQKTSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFKSL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(26022..26924)
                     /locus_tag="LP245_001222"
     CDS             complement(26022..26924)
                     /locus_tag="LP245_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1519152.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            27154..28557
                     /locus_tag="LP245_001223"
     CDS             27154..28557
                     /locus_tag="LP245_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL1519153.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            28554..29990
                     /locus_tag="LP245_001224"
     CDS             28554..29990
                     /locus_tag="LP245_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL1519154.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            30135..31061
                     /gene="trxB"
                     /locus_tag="LP245_001225"
     CDS             30135..31061
                     /gene="trxB"
                     /locus_tag="LP245_001225"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBL1519155.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            31275..33002
                     /locus_tag="LP245_001226"
     CDS             31275..33002
                     /locus_tag="LP245_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBL1519156.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIQKMTEE"
     gene            33018..33368
                     /locus_tag="LP245_001227"
     CDS             33018..33368
                     /locus_tag="LP245_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL1519157.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(33463..34323)
                     /locus_tag="LP245_001228"
     CDS             complement(33463..34323)
                     /locus_tag="LP245_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBL1519158.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            34415..34843
                     /locus_tag="LP245_001229"
     CDS             34415..34843
                     /locus_tag="LP245_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL1519159.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            35005..35181
                     /locus_tag="LP245_001230"
     CDS             35005..35181
                     /locus_tag="LP245_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBL1519160.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            35208..35654
                     /locus_tag="LP245_001231"
     CDS             35208..35654
                     /locus_tag="LP245_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBL1519161.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT        11692 a         6340 c         7611 g        10080 t
ORIGIN      
        1 aattctaacg ggattctgcg tcgtaatgga ctgccgaaat caatggattt tagagaagtg
       61 aatcagacat ttatttccag tgtcagcaat caacgtaatt atattccaag aaaatcattg
      121 aattacagaa caccaatcga aatatttttg agctatgtac aagaagcatt ttattctagc
      181 ttaatttgac aaatcatata taattaagaa tgcgttttct attacattgg taattaaata
      241 aaaacgtttt ttttaattgg tagtactttt ggctagacaa tgataaaatg gtagagaaca
      301 ctctaataga aatgaggtag catgaatgtc agaagttgta aaagttagcc aattagtaaa
      361 aaaattatct ttggaaatcg tcacaggcga cgagaaaagt ttagaccgcg tcatcgtgac
      421 tggggacatc tcacgcccag gactagagtt gaccggttat tttaattatt attctcataa
      481 tcgtttacag ctatttggca gtaaagaaat cagttttgcg gaacggatga tcccagaaga
      541 gcgtttgatc atcatgagaa gattatgtag tgaagatatg cccgcattta ttatttcaag
      601 aggattgccg gctccggaag aaatgatcca agcagccaat gaaaatggga tagctgtgct
      661 gcgttcgcct atctcaacgt ctcggctgct aggtgaatta tctagttatt tagatgggcg
      721 cttagcccct cgaacaagtg tccacggtgt gttagtcgat gtctacggat taggtgtact
      781 aattcaaggg gacagtggga tagggaaaag tgaaacggcg ttggaactga ttaagcgcgg
      841 acatcgattg atcgcagacg atcgagtaga tgtctatcag caagatgaac tgacggtaat
      901 cggagaacct cctaaaatcc tggaacatct gattgagatt cgagggatcg ggatcataga
      961 tgtaatgaat cttttcggtg cgagtgcggt acgaggctct atgcaagtcc agttagctgt
     1021 ttatctagaa gcatgggcga aagataagaa atacgaccgt ttgggttctg aagacacgac
     1081 cgttgaaatc gcggaagtgg gcattccaca aataaaaatc cctgtcaaaa caggacgaaa
     1141 cgttgcaatc atcattgaag tagccgcgat gaatttccgc gcgcgtacaa tgggctttga
     1201 cgcaacgaaa acatttgaag aaagattaag tcgcttgatt gaagaaaact caggcaatga
     1261 ctagcaagga gtgacaatat gttagcacaa atcaatcgag ttgcttttga gcttgtagga
     1321 attcctatct actggtatgc attgattatc gtatcaggaa tcattattgc catgtggctc
     1381 agcagcagag aagctgttcg ggtaggatta aaagcagatg acgtgacaga ttttatgttg
     1441 tggggattgc cgatttccat tattggtgcc cgtttgtatt atgttttatt cgatcttccc
     1501 caatatatag ctgatccaat ccaaatattc aatatccgtt caggaggatt agcgatttac
     1561 gggggattga ttgcaggtgc aatcacactg tactttttta ccaaatatca ttttatttct
     1621 ttgtggacct ttttagatat cgctgcacca agtgtattac tggcgcaggc aatcggacga
     1681 tggggaaatt tcatgaacca cgaagcgtat ggtccagaca cgacacgaag tttcttagaa
     1741 agtctgcatt taccgcaatt catcattgat aacatgtata tcgaagggat ctatcgacaa
     1801 ccaacctttc tttatgaatc actttggagt ttgattggat ttattctgct tttggttttg
     1861 cggaagaaac cgcatctttt gaaaaaagga gaagtccttt tatgttatct aatgtggtat
     1921 agtttcggac gtttctttat cgaaggatta cgcacagaca gcctttactt tttaggtgtg
     1981 atccgcattt ctcaattatt gtctgctgtt ttacttgtcg gcacattgat tctgtttatt
     2041 tggcgtagaa aaaaaggaaa tttaccggat tatgaccgct cattaggaaa aaatcaacaa
     2101 attatttgat ttttagagcg ttaaaaatga aaaaaatttc aggagtggta aaatgaatta
     2161 tagagtagcg gttttaggac caggctcttg ggggactgct ttagcacaag tcctcgctga
     2221 aaacggacat gacgttcgga tttggggaca tcgtgcttca caagtagaag aaatcaacac
     2281 ccaacacacc aatcaacgtt atttaccaga tcatcatcta cccgattcca tccgagcatt
     2341 caccgatatg gaagatgcag taaaagatgc agatgcggta ctattcgtta tcccgacgaa
     2401 agcgatacgt tctgttgcaa aagaactagt tgccaaattg aatacgaagc cagtgatcat
     2461 ccacgcaagt aagggattag aacagggaac gcataaaaga atctctgaaa tcttgttaga
     2521 ggaaatcccg acagaaaaaa gaaaagctgt tgctgttctt tctgggccaa gccatgcgga
     2581 agaagtagca aagcatgaca ttacgacgat cacagcggca agcacagatg caaaagcagc
     2641 aaaatatgta caagagctgt tcatgaacca ttattttcga atctatacta accctgatgt
     2701 ggttggtgta gagatggggg cagctttgaa aaatattatt gccattggag ctggtgctat
     2761 tcacggctta gggtttggcg ataatgcaaa agcggcaatc atgacgcgcg gattagctga
     2821 gatcagccgt ttaggtgtag caatgggtgc caacccgctg acctttattg gcttaagcgg
     2881 agtaggcgat ctagtcgtta cttgcacaag tgttcattcc agaaactggc gcgcaggcaa
     2941 cttgttagga caaggacagc ctctagaaga ggtgctagcc aatatgggaa tggtcgttga
     3001 aggtgtgaat actactcaag cagcgatgga actagcccaa atgatggaaa tcgaaatgcc
     3061 catcactcaa acaatctatg aagtgctgta tgaacaaaaa gaaatcaaaa cagccgcaaa
     3121 agaaatcatg ttacgtgatg ggaaaaaaga aaatgaattc tcattaacaa ttttttgaag
     3181 gagcgaatgt atatgaaagt aaaaaaagca gttattccag cagcaggatt aggaacaaga
     3241 tttttaccag caacaaaggc gatggcaaag gaaatgttgc caatcgtgga caaaccaacg
     3301 atccaattca tcgttgaaga agcgttgaaa tcaggaatcg aagacatctt gatcgttaca
     3361 ggaaaagcta aacgaccaat cgaagatcac tttgattcaa atatcgaatt agaaacaaac
     3421 ctaagtgaaa aaggaaaaat cgaattattg aaattagtag aagaaacgac agatgtcaac
     3481 ttgcatttca tccgtcaatc tcatccaaag gggttaggac acgccgttct tcaagcaaga
     3541 gcctttattg gaaatgaacc gtttgtcgtt atgctaggcg atgatatcat ggaagacgaa
     3601 gtaccattga cacagcaatt gatcgatgac tatgaacgta cacacgcttc tacgattgcc
     3661 gttatgcaag ttcctcacga tgaaacttca aaatacggaa ttatcaaccc aggggaagta
     3721 ctggaagatg ggttatacaa tgtcaaaaac tttgttgaaa aaccagatcc aagcaaagca
     3781 ccaagtgatt tagctattat tgggcgttac ttattgactc cagaaatctt tgatgtatta
     3841 tcagaacaac aaccaggtgc tggaaatgag atccaactaa ctgacgcaat cgatacgttg
     3901 aataaaacac aacgcgtatt tgcccgtaaa ttcacaggta aacgttatga cgttggtgac
     3961 aaatttggtt ttatgaaaac aagtattgaa tatggtctga cacatccaga agtaggggca
     4021 cctttgcgtg aatacatcat gtctttaggt aaaacattag aagcagaagg aagcaagatc
     4081 gatcataatc caaaaggaat aacagaaatc aaagaagaaa agaaaaaata atcatttttt
     4141 tctaacgagc ttcagctgct aattgaataa aaagtagttg aagctcgttt ttatttgttt
     4201 aaaaaacacg aaaatgctat ccttatagaa aagagagaca agaagggagt ttgatcatgt
     4261 caggaggaga aattgcagga ttgatcgcag caatcgcctt tgcgatactt gtcgttttca
     4321 tcattcgcgt attgttgcaa gtttccaaaa ctttagaaaa agtagaccag actgtcgcag
     4381 aagcaaatac gacaattgag atcgtcacaa aagacgtaga tcttttatct agacaagtag
     4441 aaggcttgct ggtcaaaagt aatgagctgc tcttggatat caatggaaaa gtcgcaacga
     4501 tcgatccatt gttcacagca gttgctgatt taagtgaaag tgtatcggaa cttaatcatt
     4561 ctagtaaaaa catcgtgacg aaagtcggcg gaatcggaaa aacgacagct aaagcgactg
     4621 ttgccggaaa agtcggtgga acagcgatga aattttttaa aaacaaaaaa catactgaaa
     4681 cgacaggagg aaaataagaa tggctaaaaa aggtggattt ttattaggtg cagtagttgg
     4741 aggtacagcc gcagcaatcg ccgcattatt gttagcaccc aaatctggta aagaacttcg
     4801 ggatgaattg gctgctcaag cagatgattt gatggacatg gcttcagatt acacagatat
     4861 ggcaaaagaa aaatcagctg agttaacagg cattgcaaaa gaaaaagcgc aagatctttc
     4921 tcaacaagca ggggatctag caggtaatgt taagcaaaag gtaagtgaat cagcagagga
     4981 agcaggaagt gaatcagatg atatcttgtt aaacctcaaa gaacaatcag ctgatttatc
     5041 taatcgtttc aaaaaaacag cagaagatct gaaaaaacca gcagacgaat taggtagtat
     5101 tgctaaagat acttcagaag atatcatgat cgatgtaaaa gatgctgcag ataaagcagg
     5161 agagacggtc aatgaaggaa tgtcagaagc aaaaccagtt gcagatgaca caaaagaaat
     5221 gttgaaaatg gcaaaagaag atgcaaaaga agctaaaaaa gaaatgaaag atacaatgac
     5281 agattcgact accaatcact aagaatactc atttctagaa taaaaaggtg agagcggacc
     5341 agctcccacc ttttttattt tcattactct aaaacaagta attcttttgg tgtagtcgtg
     5401 aatggcacac aaccatcact tgtcacatac acacaatctt cgatacgtac ccctactttt
     5461 tcaggaatat agattcctgg ttcaagagag aagcacatcc cttcttcgat cactaagtcg
     5521 tttccttcta caagagaagg gaattcgtgg acggttgtcc caattccgtg acctaaacgg
     5581 tgattgaaat attcgccgta gccatagctg ttgattacgt ttcgtgcgat ttgatcaagt
     5641 tcacctgctg tcacacctgg gcgaactgcc tcttgtgcgg caagctgtgc ttcaagagtg
     5701 atgttgtaga ttttttcttg gaattctgtt ggtttttgat aagcaactgt acgagtagca
     5761 tcactgcaat agccattcca aacaacgcca agatcgaata acactagttc atttggtgaa
     5821 accttcgtgc ttcctggtgt accatgaggg cttgcagcat ttgctcctgc aaggactaag
     5881 gtgtcgaaag acatttgtga aacaccttgt ttttttaatt ggtattcgat ttctgcgata
     5941 attgcttgtt cagtcacgcc ttcttttact gttttgaagc caatttcaaa ggcaacatcg
     6001 gcccatttac cagcttcgat cagtttgtct ttttcttcta ccgtcttgat cagttgcaga
     6061 cgctggataa tagaagttag atcagtgtaa gaatctgcac ctgtcaagat atcagagata
     6121 gcatcgaagc gatcgacagt cagagcattc ttttcaatcc ctacattacc aggttgccca
     6181 tagcgtgcgc gaagctcttt tccgatgatc tcccaagggt tttcgctgtc taagtagcca
     6241 cgtacatcgt acgcccagct gctgttttga gcatcttcaa cttccagagc aggagtgaaa
     6301 aggaaaggat cttgttcaag agggataaaa agagctagta cacgctcgtg aggatcactt
     6361 tcatatccgg aaaagtaagc gatgtggcca gggtcgctga tataagccaa ttctacttgg
     6421 tgttgtgcca tccattgacg tagttcattg atttttacgt tattcatttg gcaacctact
     6481 ttctaaatta attttgtatt caataattgt accactgatt gattaaaaga ccaacgttct
     6541 taaaactgaa aaaagtaaaa attttcatga aaacagagat aaaacggttg caattgttga
     6601 gattatttga tatcctattt tagaaatgta agacgtattt tcagaaaaca tataaaatat
     6661 gaataggaga acacaaatgg aaaagcaaac aatcactatc tatgatgtag cgagagaggc
     6721 aaatgtttcg atggctactg tttcacgtgt cgtaaatggc aatccaaacg tcaaaccagc
     6781 aacaagaaaa aaagtcttgg aagttatcga tcgcttggat tatcgtccaa atgcagtcgc
     6841 acgtggcttg gcaagtaaga aaacaacaac tgttggggta atcattcctg atgtcagcaa
     6901 tatgttcttt gcctctttag cacgtggtat cgacgatgta gcaacaatgt acaaatacaa
     6961 tatcatctta gcaaactcag atggcaacga tcaaaaagaa gtcaatgtat tgaataattt
     7021 attggctaag caagtggacg gcgtgatctt tatgggtcac catatcacag acgaaatccg
     7081 tggagaattt tcacgttcaa aaacacctgt tgtactagct ggttccattg atccagatga
     7141 acaagtaggt agcgtaaaca ttgattatgt atcagcaaca aaagatgcag taaataaatt
     7201 agcaaaaagc ggcaataaaa aaattgcttt tgtcagcggt gcgctgattg atcctatcaa
     7261 tggtcaaaac cgtctaaaag gctataaaga agcattaagc gaaaacaatc taccatatag
     7321 cgaaggatta atctttgagg cacaatacaa ctttaaagat ggtctgtctc tagttgaccg
     7381 gatccataat agcggtgcaa cagctgtcta tgtttcagac gatgaattag ccattggtat
     7441 cttggatggt ttattagacc gtggcgtaaa agtaccagaa gaattcgaaa tcatcacaag
     7501 caacaattct ttactgacag aagtagctcg tcctcgtttg acaagtatca cacaaccatt
     7561 atacgattta ggagcggtat ccatgcgcct attgacgaaa atgatgaata aagaagaagt
     7621 cgaagaaaaa acgattatct tgccttatgg aatcgaagaa aaaggatcaa ctaaataata
     7681 aaagatcaat catttagagg ttgttccaaa agtggccaac ttctggaaca acgtttattc
     7741 gagaaaaggg gttatgacaa aattttgtca taaccccttt tttttgtgac tttaaaaaaa
     7801 gagaaaatgg cggaaacaaa ccttacgtcc atcgtatacg acacaatctg tgcgtagatg
     7861 ctacattttg ttcactacta tcaaaattac tttaaaatga aaacgtgata aaaaagaaag
     7921 tagaaaagta gaaaagtaac tctaaaaaat ccaaaaaaat ccaggctcga ttgcgtactt
     7981 atcttaaagg agaaacaatc catcatacat aacccgaaag gagacttcta tttgcctaag
     8041 aaaagacgaa agaccatagt catcattttg accattcttg ctataggaat cggaggaaaa
     8101 ttttacatgg acaaaagaga agcacaaaga cagaaagatt tactcgcagt agaaaaacaa
     8161 tccgtcaaag ttctgaaaaa tacctttgca gatatcaggg aagtgaaggt agaagaattt
     8221 aaaaaaaacc ctgttactgg atgttatggt gcacttgtga caatgacaaa taatgaaggg
     8281 aaatctgttt attttgatta ttttttttca aaacaaatga atgaaattag cagttatggt
     8341 gtagaaaatg aagaaataca aaacgaaggg gttactactc ctaaaataag agttatttat
     8401 tctaatggag aggcggagga agtgtgacag taaaagacga agagtataga tatataagtg
     8461 aacatgttta ttggctagat ccaaaacatc ctcaatatag taaaagttac aaagaaggcg
     8521 ccattaaaaa ctttggagaa acaaaattcc aaatcctaaa aatcaaagac tcattggatg
     8581 gcatgcaggc gatggctgca gcgccaatcg tccatagcaa attggagaaa aatttcaaaa
     8641 ataaaaaaat tcctacaaac tttcgcgtac ttaaataatg aaggtatcaa tacttacata
     8701 aaaagaaagg aggcacgttc ttgtctcgga aaataagaaa actcagctta gccattttat
     8761 taatcgtcat attaggaatc ggagggaaag tctatatgga caaaagagaa gcacaaagac
     8821 agaaagattt actcgcagta gaaaaacagt cagtcaaagt tttgaaaaat acttttgcgg
     8881 atatcaagga agtgaagatt gaaaaatctg ctcgaaatga aatgacggga gcatatcgta
     8941 tgtttgtgac aatgataaat aatcacgatg agtctgttta ttttacgttt ggattttgga
     9001 aagaacgaaa tgaattagga gattatggcg tagaaaataa aagtatacaa aaagagggga
     9061 ttacagtaaa taaaatcaga gtaatttttt ctaataataa ggaggaatat atttaatgat
     9121 ggcagacaaa caatacagtg ttattagtga ggctgtttac tggctagatc ctaaacacag
     9181 agactatgat catacttata aagaaaattc tattaaaaaa attgatagtt ataattttaa
     9241 aatcctaaaa atcaaagact cattggacgg catgcaggcg atgggtgtag cgccaatcaa
     9301 gaacggtaaa gtggatcttt ctcaagtagt gattgctttt gcaggaacga acttaagtga
     9361 ttggaaagat ttggaaacgg atgcaaggag tatcatgaat ctctatggga atagaccagg
     9421 agcaagtttt tctgaaaaag caacaacaaa caagatttta tccgttagtg gattgaaaac
     9481 agcggggcaa atcaattcag cgattgcatt tgctaatgaa gtaaaaaagg aatatggaga
     9541 agctgctatt tctactaccg gccattcatt aggtggattc ttagcattat atgtagcagc
     9601 agagaaacaa tggaaaaatg tcggcttaaa cgggccggac ccgtatgatc tcttatcacc
     9661 agaagcaaaa aaatgggtgg aagaaaatcc cggtatgctc accaattacc gaaatcacgc
     9721 cgattttatc ggtaattttg gtggtaatgg cacaggtgct gaagttcgga tcagtatgga
     9781 aacagcattc ttgaatctgc ttgcttccca cagtttaacc tcttggaagt ttgatgaaaa
     9841 tggaaagctg attattcctg aaaatgaaaa taatgttaaa gctcgaaaac aacagaaaga
     9901 aaaccaagcg acccagttgt tttcctatca gttgcaagaa ctgaacaaca tacgtaaaaa
     9961 actacgatta agtggcggcc ggctgacagt taatgaacaa atttacttag atgacacaca
    10021 agctaggtta gtagtggaaa agttatcagc aaaaatgaaa agcgctatgg aagaagttat
    10081 ccgcatcaat caaagaggaa tttttgagct agagaaaaaa tggcatggca agaaggcttg
    10141 cggcaagcac gtgttgtcgc cccttcgttg actgaacagg aaatcataga agcattagct
    10201 agtgttgtcg ccacaaaaga gaacttagtc gattctgcga aagaagtcta tctgctgcga
    10261 atcaataagg caagacgtat gggggaggcc tttgatacat tggtgaagga gatccaagac
    10321 aaaatcaatg aaatcgtgac acgagatcga gaattagcac agcaattcaa ttaaaggaga
    10381 agtagatgaa actagaagaa ttggaaagag attatcgaag tgaacgaaga caattagaag
    10441 ctcaagaaga tgaattgatc cactttaaga atcaaggatt acgattgatg gagcaagagg
    10501 agcagcgact gcatcatgta ttaaagaact tagctttaga taatgagcct ctgtttcaag
    10561 caagacgaag ttattcgaat tatcaggagc attatcaaca agccctacaa gtagaacgac
    10621 gaaaactcta tcagcagcaa gacgaactag aacgttccta tcgtcaaaaa atcagacaaa
    10681 taactatgga gaaatcatct tatgaatgaa tttttaatgc aattactaaa agaattagag
    10741 aaaaatctac atcgatcaaa tgtacgttca gttggtatgg ggatatctca gcaaatttgg
    10801 gcagaaaaac gattgacaga tcaaaaccac caaatgactg cagaagaagc tgctcaagaa
    10861 ttttctaacc gacatgtaca cttgaaagaa tcagtaaaag ggcaatttgc agaaaaacta
    10921 accgaattat tccaaagaca agaaaagaaa ttaaaacagt ttcgttagta aagttatata
    10981 gaaaaatttt gtgaaaatgg cttttcacat ttttacataa atttgtctta atatcgtaga
    11041 tgcaagcttt tgaacaccat ttattcggaa aaagggagct gtgacaagat ttttgtcgca
    11101 gctcccttta attctgatta atctattaga tcaatcatct ttatcgtctg attctttggt
    11161 ctctggattc gctctagcat aagctgaagc ggtgttccag taatctgtat agttttcatc
    11221 agtaccgcca acgccgaatt taaaggcgct tttcttcgga ccattttttg cccaaagtga
    11281 ttccactgtt tttcctggcg tttggataga ttttttattg acagtaactt ttccagctgt
    11341 ttgtcctgtg aacccagata cttttttctt catcacatca gatgataagt caaatttctc
    11401 atcagtgccg aaaatctcag ggtttgcttg gtaagcttga ttgattagat tggcaagata
    11461 attagccgaa cgtatccttg cttggctgtc cattccagta ttgtcatcgt gtcctgccca
    11521 gctactgata gtgatagacg gagtagagac gatcagccat gaatctctgt attcgttggt
    11581 agaaccagtt tttccgaccc aatctgcttt tcctagattt ccgtttaagc ttgaaatgac
    11641 atctttgaat ggtgtagtga ttttttcatt gatcacactg cgcatcatgt cattcatgat
    11701 cgaggccgtt gcttcggaat aaatacggac agaattactt tcatgtttat aaatcacatt
    11761 acctgcatta tctgtgatgg aatcaatgat atagccttct tcgtagacgc caccattagc
    11821 taaggcctgg aatccatttg tctgttgaag cgtcgttaca tctactgtcc ctaaaggagc
    11881 agattcaacg ccccaattat catttgctgg gtagttcatc ttcgccaagt agtgctcgta
    11941 agcatattgt ttcgatccac ccgaattcaa tacgtcttgg tataagtgat aagctgggat
    12001 attgttggac cattccagtg actcacggac ggtttggaag gtgttcgacc cttcattggt
    12061 cgcattgacg attttctcgc cagcattttc tccttcttgc caagtcgttg cataatctga
    12121 tacacgggat tctgatccga caagtcccat atcgattgca ggaccgtaaa caagaaccgg
    12181 tttgatggat gaaccagctt gacgttctgt atcaaaggcg tggttatttt gattctggct
    12241 gtaattccgg ccacccacga atccatagat acgtccagtc ctattgtcca tcaatacatt
    12301 tccagtctcc acttggctac cagcaccatc atctaacata tagccgtaat tttctacgcc
    12361 ggtttgcaat gcagcataga tatctttatc gatcgtcgaa tggatcgtat atcctttgtt
    12421 ttggatcgtt tgctgtgctt tttgataata agcttcactg accgatgaat ctgacatatc
    12481 agcattatct ttttctgcca attgttgtgc aataatcctt gttgcttcgt tcatcacggt
    12541 ataatacaag aattctctgt cagtctgttc cgcgatttgt tgtgggagaa agtcttttgt
    12601 aagatcatag gctttcgctt cttcgtattg ttctttcgta atttgtcctt cacggtacat
    12661 actgaataaa acaaaatctt ttctggcaag accggcagaa agatcttctt ttagcgcgcc
    12721 tgtattcgtg tagggactat acgtgatagg gctttgaggc aaaccagcga tataagcagc
    12781 ttgtggcaga gtcacatctt ttgcatctac accaaagatt cctcttgcag cttcctggac
    12841 tccagcaata ttttgcccct tattattccg accaaatggc gagacattca aatacgtagc
    12901 aatgatctca tcttttgaaa agtatttttc tacttgtgca gaaagaacga tctcgtttgc
    12961 tttacgtttg aatgttgttt catcggttag gatctgctgt ttgactaatt gctgtgtcaa
    13021 agtggatcct ccagacgagc cgatgccagt agcttctgaa actaatgctc gtaaaacagc
    13081 tttagggaca taaccttggt gtttatcgaa gtattcatct tctgtactga taatcgcggt
    13141 tttcaataaa ggcgaaatct tatcagatga aatagtcgtc cgcatcagat ctgtctggat
    13201 ttttgatatc tctgtattat ctgcataaac aatctttgac gtttccgtaa tgtttcctag
    13261 ttctgtctgc agttcttttt tagtcggcaa ttgtgtgtct tcgacaagat aggcaaagta
    13321 gccagcacct attccgatac ctagagctgc gaacaacaaa agaagaacag taataaaaac
    13381 agtcaatgat tgaaacactc taaaaataac cttaggaaca aaccattttt ctttttttct
    13441 tctattctgt ttttttcgag tatttttgcg tggcaaaagg gtcacctcaa ctaatggttt
    13501 tatttcgcta attatagcaa ataataagac aaaaaaacag acaaggctgt ttttgacagg
    13561 aatttctttt tcgaatgaga taaaacgtga ggaaatgatc ttttttatga aagagttctt
    13621 aagcttttct ttagagaaag tttcagttac tatggagaac agggcaaaga aaaacaaacc
    13681 attttctttg tacatcatct taccaatata taggaattgt tcgaaacaat tgcctttcaa
    13741 ggaggaatcc atccatgtta ttaggctcac acgtcagcat gagcggaaag aaaatgctgt
    13801 taggcgcggc agaagaagca gccagttacg gatcttcgac ctttatgatc tatacaggcg
    13861 ctcctcaaaa tactagaaga aaagctatcg aagagatgaa tattgatgcc ggaaaagcat
    13921 ttatggcaga aaacggacta acaaatatcg tcgttcatgc gccctatatc attaatttgg
    13981 gaaatacgat caaaccagaa atgtttccat ttgctgtaca atttctgaga gaagagattg
    14041 ttcgtgcgga agctttaggt gctactcaaa tcacccttca cccaggcgct catgtaggag
    14101 caggggcaga aggtgggatt gctagaatta ttgagggttt gaatgaagtt ttgacaaaag
    14161 aacagacggc acagatcgct ttggagacga tggcagggaa aggtacggaa atcggtcgaa
    14221 catttgagga actagcgcaa atcatcgatg gagtaaaatt gaatgaaaaa ttatccgtta
    14281 cttttgatac atgtcatacg aatgatgccg gatataatat aaaagaagat ttctcaggtg
    14341 tgatggaaga gtttgataag gtcatcggat tagatcggct taaagtactc catatcaacg
    14401 attctaaaaa tccacaaggt tctcataaag atcggcatgc caatatcggt tttggaacaa
    14461 ttggatttga cacattgaac aaaatcgtcc atgatccaat gtttgacaac atttcgaaaa
    14521 tcttagaaac tccatatgtc ggtaaagata aaaagaaagc ttacgcacca tatggaaaag
    14581 aaattgccat gttcaaagcg caagcattcg atcccgaagt gtttcctgag ttattagcag
    14641 aagaagtcac actttaagtt ttctatctga cagcaacaaa aaaggattgg gcagtctgcc
    14701 ttgtcctttt ttgtttaaga aacaaaggag tgctttttgc agtcgttttc gccatgctcc
    14761 tttcgccccc tctttttaaa ttcagacaaa cagggtatac tgatagaaaa gtaaaaaacg
    14821 aaaagattca caagcaagta gcaaaacgtg attgaaagga cgaaaagatg ctgaacactt
    14881 taaaaccctt gatcaaccaa ctaaaaaaga aacatacata ctttattctt ggcatagccg
    14941 tattatttac aattattcgg ttgtatttat atagtaaagc aatctatgga acagatatgt
    15001 cggcaaccta tgatgatcag ctgctgattc actatgctca aaatattttg gatggtaaat
    15061 ggctagggga gtacacgact acgacacttt caaaagggat ctcctacagc ttgtttttag
    15121 tacttgcaca taaactgcat ctttcttatg cagttttgtt cggcatgttc agtattcttg
    15181 ccagcatatt ggttgcacta gcgtttaaac cgatcgtgaa gaacaagtat cttcttttaa
    15241 gtatctattt ttattttttg ttttctccga ttagttttac acatgagtat tccactcgaa
    15301 cgtatcgtaa tgctctcgtg atcccggctg ttgagatcat tatcgcttgt ttactagcta
    15361 tttattaccg taaatatagt tcccgcagaa aattgctgcc gtggttttta gggttagctg
    15421 tttcttttcc tttcttttgg ttcattcgcg aagattccat ctggcttctt ccttttactg
    15481 tagtcgcgtt aggcatcagt ttcgttcaga tcttgctagg acaagacttt tctttcaaag
    15541 aagcaaagaa gttaaaagaa cgaccatttc tcctttcgaa acaagaatgg ctgaaacttt
    15601 cattgttttt actccctcta gtcggtttct ccatcgtcta tcagtggatc gaatataaaa
    15661 acgagacaac atatggtatt gccaccatca atgaccgttc gagtggtgaa tttggacgtt
    15721 tgatgaaaca gctgatccga atagatgacg aaacgaactt aaataaagaa aacagtgaga
    15781 tatgggtctc gcatgctgca ttaaataaag cattagacgc atctcctaca tttcatactg
    15841 tttctactcg tattgacgaa ttgtatacga ctcatgcgtg gacccaaggc ggaaaagtaa
    15901 aagaattacc aggagatatc attttttggg cattgcgaga tgtggtaagc gaatctggtt
    15961 attaccaaaa caatgcaaaa gaaaccaatg atttttggaa aaaagtcaat caagaattag
    16021 aagaagccta tcaaaaggga actatcaaaa agaaaaaaga attctatctg atgggatcag
    16081 gggatggaaa gacgatgaat gatctgccaa tcgtatttgc ttttctgaaa tcaggatatg
    16141 cctatgcatg gcgatacaaa gatttccatc aaggagggaa ttatagtttc gggacgcaag
    16201 aacaagtcga acaggcccaa gaattattga atcttccact aatggataat tggatcgata
    16261 gcagtgatcc gagaacacct gatttccagt tgacaaaaac agcaaaagtc gcgaatgtca
    16321 tgataaaaat ttaccaagtt ctggccattc ccgtgctgat tgcttcaata gcagggatat
    16381 tacttatgat actaggaacc gtatttgcaa aagctgatcg tgcctattat agttcctctt
    16441 tgattgtagt caccggatta atactgacac aattggtttt tcttttcggt gtctcgtggt
    16501 tttgttctta tgcgccagaa aaaaaggatt attttttaag tgtctacact ggcgcaggcg
    16561 tgccattaac acaattcatc gtagtaacaa gcatgctagt tttcagtaaa ttgaatctga
    16621 aaaaagcttt atcttctaaa taaaaaggga actgtgacaa aagtcttgtc gcagttcctt
    16681 tttccgaata aacggtgttc aaaagcttgc atctgcggta ataagctcaa ccaaacgtaa
    16741 aatatgagga actatttttg tttggctgtt cttattactt gatgcaggac agctttttca
    16801 caacctctga tacacggtgt tccagaagta acttcttcga aaaataagcc gaaatttcac
    16861 aaaaatttga aaagcaattt tcttaaattc cttcttattt cttgaagctg cccacttctg
    16921 tcacaacctc ctttgtgtaa aagaatcagt ttctattcga tttcttctat cgtttcttgc
    16981 aaacgctgtt catatttttt gtttccttta tataaatcac caatcgtcca tgccaacagg
    17041 agaaggacaa gaacaatgat tacataagcg atttgatcag ccaatgctag ttgagctgag
    17101 gtggcttgct cgccgaagaa actttcgatt tgacctggta atcctcgtaa gttcaagtaa
    17161 gtcagactaa tcacagagaa ccagccaagt agttttacaa caaatgaatt tttgaatcgg
    17221 ctccccatct ccgcttggct attggtcatc atcagtaaag gaatcatcga gaatggcaat
    17281 gcaaaagcca gaaaaacttg ggattcattc atcaagttat tcaaagcggt atgttcttcg
    17341 atcgttcctt ttgtacttgt aaacaaaaca caaatcaata caggaatcac agaaagcaat
    17401 cgtgtgacta gtcttcttag ccaaatcggg atacgcatat ggatgaagcc ttccatgatg
    17461 acttgaccgg tcaacgtacc agtaatagta gagttctggc cagaagcaag aagtgctaca
    17521 gcaaataaag tggacaagat accagatttt gcgacagcaa tcaagatacc attgctcata
    17581 gctgatggat cagataaagc ttcatacaga ccaaaaaagg aaggatcttg gacagaaccg
    17641 gttttgaata cagcgacacc catgatcaat agcagtgcat tgactagaaa agccattgac
    17701 aactggatat tagaatccca agtagaaaag cgtaccgctt gtgctacatc ttcttcatct
    17761 tggtgatcga tcttccgagt ttgagaaact gctgaatgaa gatataagtt atgcggcatg
    17821 actgttgcac caataatccc taaagctcca gtcagcggag tttcaccgcc gatgaccggt
    17881 gagtctgaga atgtatgact gttagggata aagccggcaa acaaactgtg ccaatcaggg
    17941 ttagacaagc caacttgata gacgaaaacg aataaaatga cgaaaatcaa gcagacaacc
    18001 aaagcttcga ttttacgaaa cccgactttt gtcagcaata agaggacgaa aacatctaac
    18061 acagtgataa atacggcaat cactaatgga atatcaaaaa gcaggtagag ggcgattgct
    18121 gcaccaatga cttctgcgat gtctgttgcc ataatggcta attcagtcaa gatccataaa
    18181 atgacaccca atgtcttact tgtccgtgct cggattgctt gggccaaatc catttgggtc
    18241 acgattccta attttgctgc catatattgt aaaagcatag caatcagact agacatcaaa
    18301 ataactgaca tcaataaata ttggaaattt tgtccaccag tgatcgaagt ggaccagtta
    18361 cctggatcca tataacccac tgctactaat gcacctggtc cagagtaagc aagaagtgtt
    18421 ttaaaaaaac tttttccctt gggtacatcc actgttccat ttacttcagc taaagataaa
    18481 ccatttgtat gttcaataag tcgatgctta tgaaattgtt tgttggattg attattcaag
    18541 aaaaaaccac ctttcctatt tatctacgat tacattctac acctcagaaa gaaaaaatta
    18601 aagaaaaata ttcggtatgc ctaatttttt ttcgtggcgt gtcttgctgg ttaatgaaag
    18661 aaattttgtt cttctctaaa aaaaccacta ttttttgcat gaaactaaag aatacgcctt
    18721 tcttttttca ataaacttta gtaaaataaa tcattgagag caattcggaa atagaaagga
    18781 gagatttata tggtatcaac aggtattgtc gtacttattg ctattattgc tttgctaatc
    18841 ggcgcagtag gtggcttttt cctagcgcgt aaatatatga aagactattt agaaaaaaat
    18901 cctcccgtta atgaggacat gttgcgatca atgatgatgt caatggggca aaaaccatct
    18961 gagaagaaaa ttcgccagat gatgcagcaa atgaagaacc aagggaaaaa ataggttctg
    19021 acccaaagac tttttgcggg ctgatttttt cagtccgttt tttatttcgt aatttgttag
    19081 actattcaga ctattcagca aaaaagacaa gcacagacaa tcctatgctc ttgataaaga
    19141 caaaggagga gtaaaatgtc gatttttaga aaattaggtt ggttttttcg acaggaaaag
    19201 aaacattatt taattgggat tttctcccta ttcgcagtgg ccttggtaca gttagttcct
    19261 ccaaaggtga ttgggatcat cattgatgag attgccgata aaaatttatc aataaagatc
    19321 atttcctggt ggatcttatt attgatcctt gcagctctct tacaatatct ttttcgttat
    19381 atctggcgga cgaatatttg gggaagtgca gctcggttgg agaaagaact tcggcagcag
    19441 ctattcaaac attttacaga aatggacaat ctcttttacc aaaaatatcg gactggagat
    19501 ttgatggctc atgcaacgaa tgatttgaat gcaatccaaa atgtagcagg agctggtatc
    19561 ttgacctttg cagattcagt gatcacgggc ggaacaacga tcattgcgat gattttgttt
    19621 attgattggc gcttaacact gattgcgctg attcctctgc ctttactagc cgttacttca
    19681 cgagtgctgg ggtcaaaact ccacgatgct tttcgtgatt cgcaagaagc tttttctagt
    19741 atcaatgata agacacaaga aagtattact ggaatcaaag tcattaaaac atttggacaa
    19801 gaaaaagaag atctcgcgga ttttgaagaa aagattgaag atgcaattat taaaaacaaa
    19861 cgagtcaatt ttttagactc cttatttgat ccattcatta ccttgattat cggtctgtct
    19921 tatgttgcaa caattatttt aggtggaaag tatgtcttgg aaggcacgat ctcgatcggg
    19981 cagatggtct catttattag ctatatcggt atgcttgttt ggccgatgtt tgcgattggt
    20041 cgattgttca acgtattgga aagaggaaat gcttcttatg atcgcgtcaa tgaacttttg
    20101 catgaaaaga cgcatatcgt ggaacaactg ggtgcagtgc agaccccggc aaaaggcgag
    20161 ctgaatgtag ctatttcctc ttttaactat ccgaaagaag aatcaccagc attagaacaa
    20221 atcaaatttg tgatccaaga aggagaaaca ttaggtattg ttgggaaaac tggtgcggga
    20281 aaaacgacga tcatcaaatt actgatgcgt gaatacgatg attatcaagg aaaaatccaa
    20341 tttggcggac gttcgatcaa agaatattca ttgaatgctt tattaggatc aatcggctat
    20401 gtgcctcaag atcacttctt gttttcgatg accattcgag ataatatccg tttttctaat
    20461 ccaaaacttt cagaagaaga agtagagcat gcggcttctt tagcatttat caacaatgaa
    20521 atcaaggaat tgccaaaagg ttatgatacc ttagttggag aacgtggagt ctctttatct
    20581 ggcggacaga aacaaaggat ttcgattgct cgagcattga tcaaaaatcc tgaattgctg
    20641 atcttagatg atgcactttc tgcagtagat gccaaaacag aagaagctat cttgcataat
    20701 ttaaaagaaa taagaaaaga gaaaacaacc atcattgcag ctcaccgttt aagcagcgtg
    20761 atgcatgcaa aagaaatcat tgttgtcgat caagggaaaa tcattgaacg aggaacccat
    20821 catgagctgc ttgcattagg cggctggtat gaacgaatgt gggagaaaca gcaattagaa
    20881 gcgaagatag aaggaggcga ggcctgatgg atgaaaatta tcaatcggaa tggacaaaat
    20941 cgattccact taaagaacag aagaagatca tcaaacgact gatgaagttc gccaaacctt
    21001 ttagaagaac gttcatcgtt gctatcttat ttgcgtttgc tctgtctgtg atcaatgtcc
    21061 tattgccaag gatcatccaa acttttatgg atgatcatct ggctaaacag tcggctacga
    21121 cacaagttat tttgtttttt gctggtatgt acttgtttgg agtcatagtc aaaagtatca
    21181 tttggttttt ccaatggtat ttgtattcca tggcttcatt gaagacctat cagtatgttc
    21241 gggtaagatt atttgaaaag ctgcatacac taggtatgcg ttattttgat cagacaccgg
    21301 caggatcgac cgtttctcga gtgacaaatg acacagaaac gctatttgaa ttttggtatg
    21361 tctttttgat ggtattgact gggatctttg cagtcgtttc ttccttcatt gccatgtttc
    21421 aaatcaatgg agaaattgcc ttgtggactt tggtgttctt gccgatttta ggaatcgtca
    21481 tctggtatta ccagaaattc agttctcgta tttaccggaa tatgcgggaa aaattaagtc
    21541 agctgaacac gaaattgaat gaatcgattt ccggcatgcg tattatccag cagtttcgcc
    21601 aagaagctcg tttagctaaa gaatttgaac aagtgaacaa cgagtattta gacacgcgct
    21661 atgcgatgat caaaacgaat tcgattctgt taagtccgat catcaatttt ctatatgcat
    21721 tggcgattgc gttggcgttg actttgtttg ggatcgatgc gctgcattct cccgtagaag
    21781 ttggactgat ctatgcattt acgacctatg tccagggatt ttttaatcca atgtctcaaa
    21841 tgatggactt tttgagcacc tttacagatg gaatggttgc cggtagtcgt attttgaaaa
    21901 tcatggatac agaaaaatat gcaccgcaac aaaatcctgg agcagatcaa acgattactt
    21961 caggtaagat cgagtttcgc aatgtaagct tttcttatga tggagagcac aatgtattga
    22021 acaatatctc ttttgtcgct aatccgggag agaccgttgc attagtgggg cacaccggaa
    22081 gcggaaaaag ctcgatcatc aacgtattga tgcggtttta cgaattttat gaaggccaga
    22141 tcttgattga tgatcatgac attcgagaat atccaatgga agagttacgt aagaaaatgg
    22201 gattggtctt gcaagatgcc ttcttgtttt atggagatat cgcaggaaat atccggatga
    22261 tgaatccaac tatcacagac gaacagattc gccatgcagc tgagtttgtt caagcaaaca
    22321 agttcatcga tgaattacca aaaggatatc actcaaaagt gatcgaacac ggtgccagct
    22381 attctagcgg acaacgacag ctgatcactt ttgcgcgaac aatcgtgaca gatcctaaaa
    22441 tactagtatt ggatgaagcg acagcaaata tcgatactga aacagaagga ttgatccaag
    22501 aaggattgac aaaaatgcga caaggacgga caacgattgc gattgcccat cggctgtcca
    22561 cgattcggga tgcagaattg attttagttt tagacaaagg tcatatagta gaacgcggga
    22621 atcatgaaac acttctagcg caaaatggtt tgtatgcaga tatgtacaaa ctgcaaagca
    22681 gtggtgtgta aaaagtggtt gtgacagggc tccgttcagc tttaggtgat aagaaaaaaa
    22741 ttgtaaaaaa ggctttccag atttttgcat aaatttggct tatcaccgat aagctgatac
    22801 tggaacaccg tatattagaa gttgggacag tagcatagta gcattttgac ctaagcgcta
    22861 gagtgaaaat aaaacagagc ttcccagatt cttcatctgt gagcggtagt gtcgtagtca
    22921 ccagatttaa aaaagattcg acagctagtc agaagtgcct aatagccact aagaaagcgt
    22981 tgacaaaagc gcttgctttc gataatataa agaaaacgat acaacttgga tagtgattgc
    23041 ctgatgcaag ctaaacctga tgagtctccc atggttccat ggacggcttt ttgggttttt
    23101 ctttttgttt tggatacagc cctatatatc atggaaagga gtaaaacatg ctgattgaga
    23161 aagtactgaa taacaacgtc gtaataacca gagatgaaag aaatcaggaa atgatcgtga
    23221 tgggaaaagg tttggcattc aaaaagaaag tgggtgaccc gatttttgac tcatgcatcg
    23281 acaaaaaatt tcagttgaca aatgacggac tttcagaaca gttccaagaa ttggcacaag
    23341 cgattcctct tgagtactta gaaatttctt gtgaaatcat tgaatataca aaagaggctc
    23401 tacaagtcca gttgaatgat tcagtgtata ttgcattgac ggatcatttg tatacggcta
    23461 tcgaacgtca caaaatggga atatttgtac caaatgtatt gctgtatgat atcaaacaac
    23521 tatttcctaa agagtatgcc atcggggaaa aaacagtgaa gaaaatctcg gataaatacc
    23581 acatcaagtt atcagaagat gaagccggat ttatcgcatt gcatttagtc aatgcacaag
    23641 gcattcaaag ccaacaagac aatacctacc tgtttactac aacaatacag gatattctaa
    23701 atatcgtccg ctattactat aagattacat ttgatgaaga ttcagtccat ttttttcgat
    23761 tcgtcacaca cctacgtttt tttctgacac gcgtcctaga tggagaaaaa tcagaagtgg
    23821 gagaagtttc tgaggaattg taccaagtta ttcaaaaaaa atataaggat acgtttggtt
    23881 gcgttgagaa aatagcagac tttttagccg agatattcaa ctaccagatg tccacggacg
    23941 aaaaaatgta tttaacgatc catactgcgc gtttagtgca tgagaatcgt tgtaaataaa
    24001 taaaaaagga ggataaatta acaagaacgc atgaaataag ggtagtgaca ttcagttggc
    24061 taaaccttcc actaataaat tggagggaat agaaatggga aaatatcaag aattagcgag
    24121 caaaattgta gaaaatgtcg gcgggaagga aaatatcaat ggtttgacac attgtatcac
    24181 aaggcttcgt ttcaaattaa aaaacgaaga aaaagcaaat gatgagatct tgaaaaatat
    24241 ggacggtgtt gtgacggtaa tgcgagcggg aggacagtac caagttgtca tcgggaatca
    24301 tgtgccagtc gtgtttgaag aggttataag agcaggaaac cttacttttg atgaggctgt
    24361 ttcaacagaa aaaatgagac cgtttgatat gcttattgat ggaatatcgg gctgtttcca
    24421 gccattcctt gctattctag ctgctggtgg gatgattcgt ggactgacag cattacttgt
    24481 cttcttaggc gcatttgacc gcggttctgg cacatttgtt atgtttgata atatcggtga
    24541 ttctgtattc caatttatgc ctgttattat cggtttaaca gctgcccgta aatttaaagt
    24601 aaatgaattc gtagggatgt tgcttggggc agcattaatg aatcctagct tgtcgctgga
    24661 agctttgagt ggtgcagcag aagcaccact gacgaccata ttttctggca ctatttttga
    24721 agcacctatt tatcaaacag tattcggcat tccctggatt gcgcgtaact acgcttcttc
    24781 tgtcattccc attatcttta ttgtgttgtt agctagccaa attcagaaac caattaaaaa
    24841 gttagtacct gagatgatcg cgaatttctt cgttccattc ttcaccgttc ttattacaat
    24901 gcccttaggt tttttactcg ttggaccagc attcacattc gcaactgata ttttaatggc
    24961 tggatttgaa acacttttag cactttcgcc agttatttat ggagcaatcg taggcttctt
    25021 ctggcaaatt ctaatgatgt ttggtctcca ttgggcaatc gtaccaatgg gattgatgca
    25081 attttctgtg aatggctggc aaaatatcat gacacctgtt gcagtagtgt cttttggaca
    25141 aactgcagca cttactgcac tctactttaa gcttagaaat ccaaaagaca aagcaattgc
    25201 aataccagcc attgtttctg gtattgtggg gattacagag ccagctattt atgggtttac
    25261 attgccacgt aaaaaaatat ttatttttac ctgtgtcggt ggtgcgttag ggggcgcgta
    25321 tagtgggtta atgaatttaa cttcttggaa tcaaggtgga ctaggcatct ttacaattcc
    25381 caactatatt agaccagatg gtaatttaac agatgtgatt aatgtattga ttgggatcgc
    25441 cattgcgatg gtggtatcct ttgcgctgac ttttttcttt tggaaggagg aagcagatga
    25501 aacagatgat agacagaaaa catcaggtaa agaaattgta aaaacaccga tacaaggaca
    25561 aatcgctcca ctgaatgcag caaaggatgc agcttttgca caaggaacat taggtcgagg
    25621 aatcttgatc taccctgaaa aaggagaagt acgtgcccct tttgacggaa cagtcatgac
    25681 cctgttcccg acgaaacatg caatcggaat ggtttctgaa gcaggtctgg aattgctgat
    25741 tcatgtcgga ttggatactg ttcagttaga aggaaaatat tttaaaagct tggtgcagca
    25801 aggagaaaga gtgaaacaag gcgatctgtt gctccgcttc gacaagaaga aaatcgaaga
    25861 ggaaggatac agtttagaaa cacctgtgat cgtcaccaat tacacggatt atttggatat
    25921 tttggaaaat caaggggaga cggtcgggcc agacgatgca cttatcaccg cactgacctg
    25981 aacggttagg tgaaagaatg gactaggctt aattattctt tttagtccac ttctttattt
    26041 tcaaaattga aaggctcttt catgatggct gagctgatag ggcgtttatc aaatttttgt
    26101 cctacagaaa ttagatggac taaattctgt tgataatttt ctgcaaaaac acaactatat
    26161 aacacgtcta gaagataaca aatcgatgta ttgatcgtaa aattaccaat tttcgaatac
    26221 agtcgttcgc gtgtcgtaag tcgcaaagcg gctgtactca ttgaagatag cgttgaatca
    26281 ccgatactgg tcaaagctaa aattggcaca tgattttgtt tcaatatttc tgcggtacga
    26341 aggatcacat tgttttcacc cgtataagaa atcagaatcc cgcacatatc actcgtgcaa
    26401 ttgtacgctt catagaacga ttcaccaaaa gtggtgacaa tcgtgacatc cattttgatg
    26461 cgcttcattt tcagcatgaa atcttgagaa atcaaagtat tcgagttact ggcgaaaatc
    26521 acgatttttt ttgcttgaag cattagttgt ttggcttttt gcagttggtc atgatgaatg
    26581 agagaaagtg tatcttgaat cgtcatctgt tctaaagaag ccattttatt tgcgatcgtc
    26641 ataataccgt ctgtggtgga aaaaggaaga ttcgcatcta cgtcttgaaa attcccttca
    26701 agataggctg tttcagctaa aaaagcatta cgaaaactga cccagccatc aaaacccatt
    26761 ttttttgcta cacggatgag tgtggacggg tggacataac atcgctcagc aatctcttgg
    26821 atggtcattt cgccaagtgc tggagaatcg cttaagagaa actgaatcac ttcattttct
    26881 gaaggagaaa aggagatttc tttgattttt tcacgtaata acatgtagat accttcttct
    26941 tgttttttta cgtaaattat aacttttttg aaaatgattt gtaaacggat ttatgttata
    27001 tagcttaata aagacatttt ttgacaagat atttacaaaa atccagaaga aaacactaac
    27061 ttttgtaaat gttactggaa agaaacgaat ttctattgtt tgttttgttt acaaaaaaga
    27121 taataaaagt gtaaaaagta aaggagtgag aacatggcaa aaggaatcaa aatcgctacg
    27181 attggtggag gcagcagtta cacccccgag ttgatggaag gatttatcaa aagatatgag
    27241 gaattaccga tacgagaaat ctggctcgta gatgtagaag aaggaaaaga aaagcttgag
    27301 atcgtcagtc agatgtctca gcgtatgtgg gatgcttctc cgtatgaagt caaaatctat
    27361 gcaactctgg atcgggaaga agcattgaaa gatgcggatt ttgttacgac tcagtttcgt
    27421 gtcggtcaat tagatgcacg aatcaaagat gagcggatcc ctagttatta tgggatgatt
    27481 gggcaagaaa caaatggtgc tggcgggata ttcaaagctt ttcgtaccgt tccagtggtt
    27541 ttggcaatcg ttgaagacat gaagcgttta tgtccaaatg cttggctgat caatttcgcg
    27601 aacccaagcg ggatggtgac agaagcagtt atcagatatg gcaaatggga taaagtgatc
    27661 ggattatgca atgtgccagt aatggcgatg atgacagaac caacaatgct tggcaagaaa
    27721 aaagaagagc tgatctacaa gtttgccggt ctaaatcact tccattggca caaagtagca
    27781 gataataaag gaaatgaccg cacggcagaa ttgattgatc gtttatacga tgaagacaat
    27841 ggattgccga aaaatatctt tgatatcccg tttttcaaag aacaattaaa acaaatgaac
    27901 atgattcctt gtggctacca ccgctattac taccgtgaag aagaaatgct ggaacatgct
    27961 ttagaagaat atcaaacgat tggtacaaga gcgcagcaag tgaaagaaac agaagcagag
    28021 ctgtttgaat tatacaaaga tccagaattg gatcataaac ctgaacaatt gcaaaaacga
    28081 ggtggtgctt attattcaga tgctgcctgt gaaacgattg cttcgatcta tggaaataaa
    28141 gaaacacaga tcgtggtatc tacaaagaat gatggagctg ttcctgatct gccggcagat
    28201 tgtgtagtag aagtcactgc ctatgttggc gcacaaggcg cacgaaatgt agcgtttggt
    28261 tcccttcctg ctgctgaaag aggctggttg caagtaatga agaatatgga attgctgacg
    28321 atcgaagcag ccgtgactgg tgattatgga acagctttgc aagcgtttac gatcaatccg
    28381 cttatacgat caggaaagac agcaaaacgg ataatggatg agttgtttat tgcacatcag
    28441 cagtatttac cgcaattcaa ggaaacaatc agccggttaa aagcagaagg aatcgaagtc
    28501 caagatgaac tggcaagaga attatcaagc aatacacatg taatggagga agtatgatgg
    28561 gattcagaaa agatttttta tggggcggag ctacagcagc caatcaatgc gagggcggtt
    28621 atgatgaagg cggacgtggg ttagcgaacg tagacgttgt gccaatcgga gaagaccgtt
    28681 ttcctgtcat tactggaaaa aagaaaatgt ttgaatttga tgaaaatcat ttttatccag
    28741 caaaaattgc gatcgatatg tatcatcatt ataaggaaga tattgcttta tttgcagaaa
    28801 tggggttcaa gacttatcgg atgtccattg cttggagtcg tatttttcca atgggcgatg
    28861 aaaaagagcc aaatgaatct gggttgaaat tttatgagga tgtctttaaa gaatgtcaaa
    28921 agtacgggat cgagccgctt gtgacgatta cacattttga ttgtccgatg catttgatca
    28981 aagaatatgg tgcgtggcgt tccagagaac tcgttggttt ttatgaaaat ctgtgccgag
    29041 tcatcttcaa tcgctataaa ggacttgtca aatattggtt gacattcaat gagatcaata
    29101 tgatccttca tgcaccattc atgggcgcag ggctgtattt tgaagaagga gaaaatgaag
    29161 aacaaatcaa atatcaagcg gcacatcatg agttggttgc aagtgccatc gcaacgaaga
    29221 ttgctcatga agtagatccg gagaacaaag taggctgtat gctggcagca ggagcatatt
    29281 atccatacac ttgcaatcct gaagatgttt gggcttctag aaaatcagat cgagaaaatt
    29341 atttcttcat tgatgtccag tcacgaggag aatatcccgc ttatgcattg aaagaaatgg
    29401 aacgaaatgg cattcagatc gaaatggaac ctggggatgc cgcattgctg aaagaacata
    29461 ctgttgattt tatctccttt tcttattatt cttctcgagt ttcgactact gacaacgaac
    29521 tcttggaaca gactgcagga aatatctttg cttctgtcaa aaatccatat ctggaagcaa
    29581 gtgaatgggg ttggcaaatt gatccattag gcttgagaat aacgatgaat gatatttatg
    29641 atcgttatca aaaaccacta tttattgtag aaaacggctt aggtgcagtc gatacgcccg
    29701 atgagaatgg ttatgtggaa gatgattatc gaatcgacta tctggcagca catatccaag
    29761 caatgaaaga tgcagtagaa ttagatggag tcgatctatt aggctatacg acttggggat
    29821 gtattgattt agtatcagct ggtacaggtg agatgaagaa aaggtacgga ttcatttatg
    29881 tcgatcgtga caacgaggga aatggcacat tagcccgttc gaagaagaaa tcattcaact
    29941 ggtataaaaa agtaattgat tcaaatggag aaaatctttc gaatgattga tcaatgattt
    30001 ataaaagtct attgtttttc agcggatttt tcgagtataa taaagctatt cgagaaacgc
    30061 aagcagaaca atagactttt tttcgcattg gctgtaaagt atgcttactt gattaagtaa
    30121 aggagaatct acatatgtat gatgtaatcg ttattggcgc aggtcctgct gggatgactg
    30181 ctgctttata tgcttcacgt tcaaacttat ccgtattgat gatcgaacaa ggcgcccctg
    30241 gcggccaaat gaacaatacg gcagaaatcg aaaactatcc tggtttcgat tcaatcatgg
    30301 gtcctgatct agcttataag atgtatgaag gtgtttcaag atttgggaca gaaaatgctt
    30361 atggaatcgt gcaagatatc aaggatcacg gcagccacaa agaagttatt tgtgaagata
    30421 aaacttacga aggaaaaaca gtcattatcg caacaggctg tatccaccgt aaattaggcg
    30481 tacctggcga ggaagaattt gctggacgtg gcgtttctta ctgtgcagtt tgtgatggtg
    30541 cgtttttccg taacaaacgt ctagtagtga tcggaggagg agactcagca gtagaagaag
    30601 ccatctattt gacacaattt gcttctgaag tagtcatcgt ccaccgtaga gatgaattac
    30661 gtgcacaaaa gatcatccaa gaccgtgcat ttgcgaatga aaaaatttcc tttatgtggg
    30721 atacagtcgt tgacgaaatc gttgggaatg aaatggtagt gacaggtgtg aaagcacgta
    30781 atgtcaaaac cggcaatgag tttgatttgg cagcagacgg agtattcatc tatgttggac
    30841 tggatccatt aactgcacca tttagagaag cagggttgac gaacgaagct ggctggattc
    30901 caacagacaa cgaaatgaag acgaatatac caggcgtttt tgccatcgga gatgttcgtg
    30961 aaaaagattt gcgacaaatc actactgctg ttggtgatgg tgggatcgct ggacaacaag
    31021 tgtataaata cttggaatct ttagaagaaa caactgcata agtttaaaaa gagtggaaga
    31081 acggtttcaa ttgttctttt actctttttt ttcgcgtgaa atctactgaa tccgatttat
    31141 gcgaatactt gcaaccgtgc ttgataaaag aatcctttct tgatttaagc gttttttggt
    31201 cctcatactt ttatatctaa taagtgaatg ctatacttat taagaaccat atttcagaaa
    31261 gaggtgttat tttcatgtct tgggaacaag tgtatgaaca atgggtacat gaagaaaatt
    31321 tagaagaaaa cttaaaaaaa caattaaatg atctgggtga agatcctgaa aaacttgaag
    31381 atgcttttta tgcaccgttg gaattcggta ctgcaggcat gcggggaatc ttagggcctg
    31441 ggatcaatcg aatgaacatc tatacggtaa gacaagcaac agaaggactt gcacgtttca
    31501 tggatacaca aggcgaagaa acaaaacgcc gaggtgtcgc tatcgcttat gactcacgcc
    31561 atcaatcacc agaatttgcc atggaagcag ccaaaacatt agcacatcac aatatcccat
    31621 cttatgtatt cgaaagtcta cgtccaacac cagagctttc ttttgcagtc cgtcatttga
    31681 agacgtttgc gggaatcatg gtaactgcat cccacaatcc agcagcttac aacggatata
    31741 aagtctacgg cgaagatggg ggacaaatgc ctcctgcaga cgcagatgca ttgacgaaat
    31801 atgtccgtga agtcagcaat ccgttaaaag ttgaagtatt atctgacgaa gaagctgaac
    31861 atagcggatt gatcacgatc atcggagaag aagtggatgc cgcttatcta gaagaaatca
    31921 aagcagtaac gattgatcat gaattggtgg aaacaatggg gaaagatttg aaacttgtgt
    31981 acacaccact tcacggaaca ggaaaaatgt tgggcgaacg tgcgttgaaa caagctggat
    32041 tcgaacaatt cgtactagtt ccagaacaag ctgtcgcaga cccagatttc actacagtca
    32101 aatcaccaaa tccagaagaa cactctgctt ttgagtatgc gatacgactt ggcgagaaag
    32161 aaggcgctga tttgctgatt gcaacagatc ctgatgcaga ccgtttaggt gcagccgttc
    32221 gtttgccaaa tggctcctat gaagtattga ccggaaacca aatcggagca ctgtttgctc
    32281 aatatatttt ggaagcacac caatcgcgag gcactttacc tgaaaacgca gcggtattga
    32341 aatcgatcgt ttctagcgaa ttacctacag caattgcgga acactatggg gctaccatgt
    32401 tcaatgtatt gacaggattc aaattcattg ctgaaaaaat tcaacaattt gaagaagatc
    32461 attcccatac ttttatgttc ggattcgaag aaagttacgg ttatttagtt aaacctttcg
    32521 ttcgcgacaa agacgcgatc caagcattgc tcttattagc agaagtagca gcttactata
    32581 aaaaacaagg caaaacgttg tatgacggct tgcaaacgat ttttgaaacc tatggctact
    32641 acgcagaaaa aacgatttct gtgacaatga gcggacaaga aggttctgcg aaaatctctg
    32701 ctttgatgga aaaattccgt gaagaagcac caacagaatt tgccggagca aaagtcatcc
    32761 aaacagaaga cttcaaagag ttgacgagaa cagaccgtga aggaaacgta gaaaaactaa
    32821 cgacaccgcc atctgatgta ttgaagtata cgctggaaga aaatggctgg atcgctatcc
    32881 gtccttcagg aactgagccg aaaatcaaat tttacatcgg tgtaaaagga aactcttcag
    32941 aagacgcagc tgaaaaagta gccgcttatg aagcgattat ccaaaagatg acagaagaat
    33001 aaaaaaactt gagactgatg gaaaaagtgg taaactttag aagtcagtct tttttcaagt
    33061 tggaggtgaa tggattgcca gacacgcaaa aaacaaaagt agagaaagtc agccaactat
    33121 tcaaaatgtt gagtgacccc actcgtctca aaattctgct gtatctgaaa gacggggaac
    33181 aaaatgtgac agcaatcacc caagcagtgg aaatggaaca atctgctgta tcgcatcaac
    33241 tgcgtttatt aagagaaaac catgtcgtca agtcccatcg tgagggaaaa gcgattttgt
    33301 atagtcttga tgattctcac gtactggata ttttgaacca gacactcaaa catgtggaac
    33361 atcaataacg ataggtgcaa atagagacaa actggactgt gtcaacgaat cttcttcgct
    33421 gacacagtcc agtttttttt aagaaaaaga caagaaaaac tgttagtctg tttcttcggt
    33481 ggtttcagtt ccataataac tatgatcttc taggtctaaa gcattcaaaa taagcgaagc
    33541 tgtttcttca atagataaag aagcgacatt gattactacg cagcccagtt tttcataaag
    33601 atcatttgca aaatcgagtt cagctcgtat tttttcgata tcagaataag cagtatcagg
    33661 atttaatccg taagagcgca tccgttcttt acggatattg tttaaaatat ctgggttatt
    33721 cgtcaatccc acgatttttt taggatcaat ctcccaaagc tgtttgggaa tatgtgcttg
    33781 tgggatcaaa ggaagattgg caacttttaa atttttgtta gctaaaaaca agctcaaagg
    33841 cgttttggaa gttcgggata cgcctagcaa aacgacatct gcttctagaa acccacgagg
    33901 atctttcccg tcatcgtatt ttacagcaaa ttccattgct ttaatccgtt tgaaatagtt
    33961 ctcattcaat aaatgaaggg cgccaggttg ccgaatgggc ttgataccag ttaagcgctc
    34021 gatttctgat atcggcggag tcatcacatc aaaactaaat aattgatgtt cttcacaaaa
    34081 agaacgcgtc atctcgatca attcttgatt gatcaatgtg tgtaagacaa gagctttttc
    34141 ttctagtgca tcttgcagtg cctgcatcaa tgttttctca tctgtcacaa atgttctgcg
    34201 gaataaattg aactcaacgc taggatattg ggccatagtg gcttgcgcta attttgtcgc
    34261 agtttctcca gcagagtcgg agatgacaaa aaaagtaacg atttctgtag aatcggaaga
    34321 catggataaa acctcacttg catttttttt atgtttatta taccatactc tagaatgtgt
    34381 acttcgtaat cattttgatt tggaggaata agtcatgaaa aaacagacat tgatcgaaca
    34441 atcactagaa acattgaaaa ataacggttt taaatatact aaaaaaagag aagcattgtt
    34501 aacttattta gtgaagcgca atcgctacgt atccgctaaa gaagtttttg actatatgaa
    34561 tcaggaattc aaaggagtaa gttacgatac gatttatcga aatctccatg attttgcaga
    34621 aatcgattta ctggaagaaa ccgatttaaa tggagagatg aagtttcgtt ttcattgctg
    34681 tcaaggggaa atcggccatc accatcactt tatctgtacg gtgtgcggaa caacgaaaga
    34741 aatccatatg tgtccaatga attatttcga agaacagctc ggtggatgta cgatcgaagg
    34801 gcatagattc gagattttcg gaagatgtga aaattgtcaa taaggattta aataaaataa
    34861 catttgataa ttttaaaaaa aagcaagatt tccttgacgg tcaaaacagc attagatata
    34921 atgtttacag gacagtcttg ttttttgaga tatatttcaa taacaattac ggttactttt
    34981 taagctcgga gggagggaat taacatgtca aaaacagtcg ttcgcaaaaa cgaatcactt
    35041 gacgatgctc ttcgtcgctt caaacgttcc gtgtcaaaag cgggtacttt acaagaatct
    35101 cgtaaacgtg aattctacga aaaaccaagt gtaagacgca agaaaaaatc tgaagcagct
    35161 agaaaacgca aaaaattcta gttctgtgat gaattggagt tggtagtgtg tcactactaa
    35221 gtagattaaa cgatgacatg aaaacagcga tgaaagcgaa agataaggaa tctttacaag
    35281 tcatccgaat gatcaagtca tctatacaaa acgagcagat taaagaaggt cacgacttga
    35341 cagaagaaga agaattaacg gtgttgtctc gcgaaatgaa acagcgacgt gattctttgc
    35401 atgagtttga agaagcagga cgtgacgatt tagctgaaaa agtaaaaagt gaaattgtga
    35461 tagtcgaaaa atacatgccg gaacaacttt ccgacgaaga aattcgacaa cttgttcaag
    35521 aagcaatcac acaaactggt gcttcatcaa tgaaagaatt tggcaaagtc atgggtgcga
    35581 tcatgcctaa agtcaaagga aaagcagatg gaaaccaagt aaatgccatt gtgaaagaac
    35641 tattacaatc ttaattttat catttaaact gcggacaatc attgtccgca gtttttttgt
    35701 gctcgtaaaa aagaaatcta aaa
//
LOCUS       DAFEEZ010000023        35429 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000023
VERSION     DAFEEZ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.023"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            111..1877
                     /locus_tag="LP245_001232"
     CDS             111..1877
                     /locus_tag="LP245_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBL1519162.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            1979..3238
                     /locus_tag="LP245_001233"
     CDS             1979..3238
                     /locus_tag="LP245_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL1519163.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            3385..4686
                     /locus_tag="LP245_001234"
     CDS             3385..4686
                     /locus_tag="LP245_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1519164.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            4689..5540
                     /locus_tag="LP245_001235"
     CDS             4689..5540
                     /locus_tag="LP245_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1519165.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            5553..6368
                     /locus_tag="LP245_001236"
     CDS             5553..6368
                     /locus_tag="LP245_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBL1519166.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            6519..7685
                     /locus_tag="LP245_001237"
     CDS             6519..7685
                     /locus_tag="LP245_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1519167.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPTQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            7915..8562
                     /locus_tag="LP245_001238"
     CDS             7915..8562
                     /locus_tag="LP245_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBL1519168.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            8646..9590
                     /locus_tag="LP245_001239"
     CDS             8646..9590
                     /locus_tag="LP245_001239"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBL1519169.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            9725..11176
                     /locus_tag="LP245_001240"
     CDS             9725..11176
                     /locus_tag="LP245_001240"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBL1519170.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            11197..12033
                     /locus_tag="LP245_001241"
     CDS             11197..12033
                     /locus_tag="LP245_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBL1519171.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            12033..12692
                     /locus_tag="LP245_001242"
     CDS             12033..12692
                     /locus_tag="LP245_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL1519172.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            12818..13507
                     /locus_tag="LP245_001243"
     CDS             12818..13507
                     /locus_tag="LP245_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519173.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            13513..14469
                     /locus_tag="LP245_001244"
     CDS             13513..14469
                     /locus_tag="LP245_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBL1519174.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            14513..15025
                     /locus_tag="LP245_001245"
     CDS             14513..15025
                     /locus_tag="LP245_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1519175.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(15281..15829)
                     /locus_tag="LP245_001246"
     CDS             complement(15281..15829)
                     /locus_tag="LP245_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1519176.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(15918..17099)
                     /locus_tag="LP245_001247"
     CDS             complement(15918..17099)
                     /locus_tag="LP245_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBL1519177.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(17335..18843)
                     /locus_tag="LP245_001248"
     CDS             complement(17335..18843)
                     /locus_tag="LP245_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBL1519178.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            19002..19193
                     /locus_tag="LP245_001249"
     CDS             19002..19193
                     /locus_tag="LP245_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519179.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            19396..20313
                     /locus_tag="LP245_001250"
     CDS             19396..20313
                     /locus_tag="LP245_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBL1519180.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            20306..21379
                     /locus_tag="LP245_001251"
     CDS             20306..21379
                     /locus_tag="LP245_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519181.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            21527..22045
                     /locus_tag="LP245_001252"
     CDS             21527..22045
                     /locus_tag="LP245_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519182.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            22026..22418
                     /locus_tag="LP245_001253"
     CDS             22026..22418
                     /locus_tag="LP245_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBL1519183.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            22494..23429
                     /locus_tag="LP245_001254"
     CDS             22494..23429
                     /locus_tag="LP245_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBL1519184.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            23562..24341
                     /locus_tag="LP245_001255"
     CDS             23562..24341
                     /locus_tag="LP245_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBL1519185.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            24334..24651
                     /locus_tag="LP245_001256"
     CDS             24334..24651
                     /locus_tag="LP245_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBL1519186.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            24895..26505
                     /locus_tag="LP245_001257"
     CDS             24895..26505
                     /locus_tag="LP245_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL1519187.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            26662..27510
                     /locus_tag="LP245_001258"
     CDS             26662..27510
                     /locus_tag="LP245_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL1519188.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            27741..28220
                     /locus_tag="LP245_001259"
     CDS             27741..28220
                     /locus_tag="LP245_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519189.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            28253..30481
                     /locus_tag="LP245_001260"
     CDS             28253..30481
                     /locus_tag="LP245_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1519190.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            30610..32253
                     /locus_tag="LP245_001261"
     CDS             30610..32253
                     /locus_tag="LP245_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBL1519191.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(32326..32871)
                     /locus_tag="LP245_001262"
     CDS             complement(32326..32871)
                     /locus_tag="LP245_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBL1519192.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(32894..33379)
                     /locus_tag="LP245_001263"
     CDS             complement(32894..33379)
                     /locus_tag="LP245_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL1519193.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(33369..34181)
                     /locus_tag="LP245_001264"
     CDS             complement(33369..34181)
                     /locus_tag="LP245_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBL1519194.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(34320..>35429)
                     /locus_tag="LP245_001265"
     CDS             complement(34320..>35429)
                     /locus_tag="LP245_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBL1519195.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        11582 a         6382 c         7091 g        10374 t
ORIGIN      
        1 aaaaattcgg tatcaaaaaa ctgttaccga taacattttt gaaagcgttg tcttttgctt
       61 ctctatcact tatagtgatg acgtcatatt aaaacacaag gaggaaatca atggatacag
      121 ctgcaattta tcatcgaccg gaaagtgaat atgcatttct atatacgaat acaagatttc
      181 gtattcggct tcgtactagg aaaaatgata tcaaaaaagt atatgtgcta tgtggagatc
      241 catataccat aacaactgaa aaatggtatc aaaaacaacg accaatgaaa aaatgtctaa
      301 gtaccaatgt tcatgattat tgggaaattg aagtgacgag cgaaacaagt cgcttacagt
      361 atgcgttcca tgttgttggg gaagataaca cggactgttt ttacggtgat caaggaattt
      421 ttccttatcg agaaaatgtg attactgaac caaattttta ttttcgaata ccttattttc
      481 atcaaatcga tcgattcact attccagaat gggtaaaaga aacagtatgg tatcaaattt
      541 ttcccgaaag atttgcaaac ggggacaaag caaatgaccc cgaacacact ttaccttggg
      601 gaagtaaaga tccagaccga gaagactttt tcgggggaga tttgcaaggt gtgatggatc
      661 atttggatta cttgacggac cttggcatca atggcatcta tttttgtccc atatttaaag
      721 ccacatccaa tcataaatac gatacgattg attattatga ggtggatccc gcttttggcg
      781 ataaaaaact tttaaaaaac ttgattgatg aagcacataa aagagggata cgtatcatgt
      841 tcgatgctgt attcaatcat atgggtgtcc attcaccaca gtggcaagac gttctcaaaa
      901 acggagaaaa atcgatctat aaagactggt tccacatccg ttttttccca gtagattctt
      961 atcagatgac tgacttacca gaaactgctg aaaatatccc atatgatact tttgctttta
     1021 ctccattcat gccgaaacta aatacagcaa atccagaagt gcaaaaatat ttgctggata
     1081 tcgcaactta ttggataaaa gaattcgata ttgatggatg gcgtcttgat gttgctaatg
     1141 aagtcgatca tcatttttgg aaaaaattca gagaagcagt tacagaaatc aaaccagaca
     1201 tctatatcct tggagagatt tggcattcct ctcaagcttg gctgcaaggg gatgaattcc
     1261 atgcagtgat gaattatgca tttacagatt cgattaaaga ttattttgca aaaaagaaaa
     1321 tcacagcttc acaaatggtc agtggaatga atcatcagca aatgctttac agagatcagg
     1381 tgaacgaagg aacattcaac ttattagatt ctcatgatac tgccaggatc ttgacccttt
     1441 gccaaggtaa caaagaattg atgaagtctg tgatggcctt tatgtttctt caaaaagggt
     1501 ctccttgtat ctattacggg acagaaatag ggatgactgg tgaagatgac ccggattgcc
     1561 gcaaatgtat gatatgggag aaggaggaac aagatctaga gctattcggt tttataaaag
     1621 aacttgtttc tctaaggaaa cagttgtcta agattatttc tgaaggttct actcagtggc
     1681 taatagtaaa tgatcgtgaa gataagctct atttcacacg gaaactagag ggacagatca
     1741 tctatgttta ctttaatcag tcaaaagaac cttgggtagt agaacaggaa aatgaggtga
     1801 ttcttagtca aaattgtcag ttgttagaag acgggaaagc agagatacga caatacggat
     1861 ttttgatcat gtgttgaaaa ctgttaccgg taacaacaag aaagcgtttg caaatgaaga
     1921 tttgtgccca ttataataag ggtgtaacag cacgttgaat acaaaggagg aaatgaagat
     1981 gaaaaaaaga agtgtgaaac agttgggttt agggttaatc tctttaggaa tcttaggcgg
     2041 attagcggct tgtggcaatg gtaactcttc agcagaaggg gaagccgatg aaggaaaaac
     2101 gttaacagtt tccgttgatt ctggatataa agattatata aacgaaataa aaaacacttt
     2161 cgaaaaagaa aacgatgtga aaatcaagct agtagaaaag gacatgttcg atcagttgga
     2221 atcattagcg ttagatgggc ctgctggaaa gggacctgac gttatgatgg cagcatatga
     2281 ccggatcggt gcgttaggac agcaaggaca tctggcggaa gtaaaactgg gaaatgaagc
     2341 agcttacgat gaaacagaca aagcccaagt gacttatgat ggaaaaatct acggagaacc
     2401 tgcagtaatc gagacccttg ttttgtacta taacaaagat ttagtcgata cagcaccatc
     2461 aacgtttaaa gatttggaga atctatccaa agacagtcgt tttgcttttg agtcagaagc
     2521 aggaaaaaat acaggatttt tagctaaatg gactgacttt tattattcct atggtttaat
     2581 tgcaggttac ggtggctatg tatttggtga tgatggcaca aatccttcag atatcggttt
     2641 gaataatgca ggtgctgtag aaggaatctc ttatgcaaca gattggttca aaaatgtttg
     2701 gccaaaggga atgcaagaca taaaaagtgc aggagacttc gccagccagc aattcatgtc
     2761 caataaaact gcagcaatca ttgacggtcc atggcaagcg caaacataca aagaaaacaa
     2821 tatcaattat ggtgtagcca aaattcctac tctaaataat ggacagcctt atcaaccgtt
     2881 tggcggagga aaaggatggg tagtcagcaa ttatgctaaa aacaaagacc tctctcaaaa
     2941 atggcttgat tatgtaacga atcaggaaaa tcaagaaaaa ttctttgaaa tggtaaatga
     3001 aatccctgca aaccaacaag ctagggaaac agcaaaggct aaaaacgatg aattaacaac
     3061 agctgtgatt gaacaatatg aaacagctca agcgatgcca aacatcccag aaatgggcga
     3121 agtttggaca ggtgcagaaa acttgatgtt cgatgcagca tcaggttcaa aaacaccaaa
     3181 agaatccgca gatgaagcag taaaaacaat cagtgaagcc atagaacaaa aatactgatt
     3241 aaaatgataa ccgtccattt ttataaaaaa tggaacaggt gcttcagata aaagtggcaa
     3301 gagcgagatg gaaaattatc ttgctcttgt tgccattatc ttaaaagcag tttgcggttt
     3361 agcaagttta gagggggcat tcagatgcag caagataaaa caagcaatat caacgaaaaa
     3421 aaaatcacgc tttgttcact tattccaggg atggggcagt ttgtaaatgg ccaagctttt
     3481 aaaggtatcg tttttttcgc catattcgtc ctattcattg gtcagatgct tctgggcgga
     3541 tttcatgcat tggtaggatt ggttactttg ggaagtatac caatggaaga tcattcatta
     3601 tttattttga ttgaaggcac tttgcaattc atcattacaa tcattttctt gattttttac
     3661 ggtttgaatc ttttagacgc ttatcgagta gcgaagatgc gtcaagaggg caaaaaaatc
     3721 aatcggacga tgaaggaagt catacataat ataggtgatg aaggttttcc ttatctattg
     3781 acacttcccg cttatcttct catgattttt acgatcattt tcccagtcct agttacattg
     3841 ttcactgcat ttactaatta tgacttcaat catattccac cagccagttt aattgattgg
     3901 gtaggggcta aaaacttttt tagtatcttc tttttaagct catatcgtaa tacttttttt
     3961 gcagtctttt cgtggaccgt gatttggact ttatgtgcaa caactttgca aatcaccctt
     4021 ggtattctca cagcggttgt tgctcaccag aaatttatta aattcaaacg tattttcggt
     4081 atcattttct tattaccatg ggcggtccca gcttttatta ctatcatgag tttttcgaat
     4141 atattcaacg atagcgtagg tgccatcaat actcaagtga ttcctttcat aaaccagctt
     4201 ccttttgtag atatcagtgc aatctcttgg aaaacggacc cgaactggac gaaagtagca
     4261 attatcttag tgcagggctg gttaggattt ccctatatct atgtgatggt tacaggaatc
     4321 ttacaatcga tttcagaaga cttatatgaa gcagcaaaaa tcgacggagc aaatgcatgg
     4381 cagcgctttt caaacatcac gcttcctgct gtcttcctag tggcagcgcc aacatttatt
     4441 acacagtata cggggaattt caataatttc tccatgatct atctgtttaa caatggcggt
     4501 cccggaagcg taggcggagg agctggttct actgatattc ttatttcctg gatctataaa
     4561 cttacgactg gaacttctcc gcagtattct atggcttcag caatcacgtt gattatctcc
     4621 gtcatcgtta tctgtgtgtc attgctggta tttaaaaaga caaatgcgtt caatatgggg
     4681 gattaacaat gaaaaaattt cattcgagtg ctcgattcca aaaacgactt tctcactttt
     4741 ttacttactt ttttctttta atactgtcag tcattatcat ctatccgctt ttgatcacag
     4801 caagtactgc cttcaagtca ggaaatattg cagcttttag tttagatctt tcaagtgact
     4861 ggactttagg aaactttact cggctattca gtgaaacact ttacgggact tggtataaaa
     4921 atacattgat catttctgtc ctaacaatga tcgtacaagt gactgtagta actttggcgg
     4981 gctatactta tagtcgctat cgttttatcg gccgcaaatc aagtttgatg ttctttttag
     5041 tgattcagat ggtaccgact atggcagcat tgactgcctt ttatgtcatg gctttcttat
     5101 tagaagcgct cgataagtac tggttcttga caatgatcta tataggcggt ggaattccaa
     5161 tgaatacttg gctgatgaaa ggatactttg acactgtacc aatagattta gatgaatctg
     5221 ctaaacttga tggggcaggg catttcagga tttttttcca gattgtatta ccgcttgtca
     5281 aaccgatgct cgccgttcaa gcattatggg cttttatggg accttttggg gatttcatgt
     5341 tagctaagtt cctgcttcga acacctgaaa atcagactgt tgctgtcggc ttacaaacat
     5401 ttatttctga tgtgacaaac caaagagtct ctctttttgc tgctggggca attttgattg
     5461 cactaccgat ttgtctatta ttcttctttt tacaaaagaa ctttgttacc ggcctgacat
     5521 ctggcggaac aaaaggatag gagcagagta tcatgcaaac atttccgtta aactattttt
     5581 ccgcattacg tacgccaact caagtgtttg cgggacgcaa actattatca tggcctaaat
     5641 ttttcttgat atttgtattt ttagtttcct tgatggtcat gcctgtgact cttttttatg
     5701 ccaatcagat ccaagcgatt ccattagaac aatttctatc cgttcattcg ctgatcgatg
     5761 aacaaggaac ccaaaaattt tctgaacttg aattatctga aactgggtta caagcatcgc
     5821 aacaaacgat agctgtgacc cctgaaattt tggtaggtgt gtctttatct gagaaacaac
     5881 aatccgatca tggaactttt attgattttg agaaggaaca atgggtgatc caacaaaagg
     5941 ataaatctgg tatacgccgc tatacgatga attatagccc atctttccaa ccagattctg
     6001 tacgtacgcc cgaagatttc caacgatttt tagaaagaga attttatgcc agtaatcgtc
     6061 caacaatcat tttatcttat agtttaagtc ttggtcttgt cctatttgtc atgacgagtc
     6121 tcattttatt cggggcttcc tttttcttgt ggatgacaag aaaaagccaa ctttcatcca
     6181 ttcatacatt caaagagagt gcaaatttga tgctgaatgt tatgggaata ggttccatgg
     6241 cagcagcagt tgtagggttt atccactttg actttatctt gatgctaagt gtccaaacaa
     6301 cgataactgt cttgctgctt ttatgggttt ttgtcaaaac aagattcaaa gataagcgtg
     6361 tcgaatgaca agtttaagcg atttatgcga caatgaatgt gaaaaaaatg aaaaataaag
     6421 tagtttttga aaaatttctg aaaaaattaa acttcttagt tgattctttt cttttttagt
     6481 attaacgtaa tagggtagtt tttttaagga ggaaaatcat gttagagaaa actttataca
     6541 atcaattatt ttcacgttct ttctcgctcc ctgtcgaagt aaattattgg gacggtacaa
     6601 cgaaacaata cggagatacg gacactccta cccaaatcaa aatcaatatc catgaagaaa
     6661 tcccaatgaa agagattaca agtaacgcat ctttggcact aggagaagcc tatatggatc
     6721 atcgaatcga gatcgaggga agtatccaag cattgatcaa cgatgcttat cagcaagcaa
     6781 acagcttttt acgaggaaaa gattatctaa aatggctgcc aaagaaagaa aaacatacga
     6841 aacaaaaaaa caaagaagat atccatgcgc attatgactt aggtaacgac ttttataaac
     6901 tttggctaga tccaactttg acttattctt gtgcttattt caatacacct gaagatacgt
     6961 tggaacaagc acaaatcaat aaagtccatc atatcttaga caaactcttt atcaaagaag
     7021 gcgaaacgtt gcttgatatc ggttgtggct ggggaacatt gatgttcact gctaccaaag
     7081 agtataatgt caaggcaact gggatcacac taagtgaaga acaatacgat ttgattacca
     7141 aaagaataaa agaagaacat ttagaagata aatgccgtgt attattaatg gattaccgcg
     7201 aactaaaagg cgaaacgttt gatcatatca caagtgtagg tatgttcgaa catgtaggtt
     7261 ctgaaaatct tgaaggttat ttcaaagtgg taaaagattt attgaaacca aaaggaacag
     7321 ctttgatcca tggaatcagc cgacaacaag gcggtgcgac aaatgcttgg atcaataaat
     7381 atattttccc tggcggttat gtccctggtg ttactgaatt agttgataat attacaaaaa
     7441 acgatttgca actgattgat ttggaaagct tacgtcgtga ctaccaattg acattagaac
     7501 attggacaaa gaattttcat caagtccaag atcaagtcac gaaagaaatg ggtgattcct
     7561 tctatcgaat gtgggatcta tatttacaag cttgtgcagc ttcatttgaa tcaagtaata
     7621 tcgatgtgat tcaatatttg cttgttcaac ctggaaacaa tgacatccca atgcatcgtg
     7681 cataattgag gcaaaagtac tgtttaaaga ctatttaaaa agaagctaag ttttatgatg
     7741 ctccagaagt gaactttttt gtctaacttc taggattgtc tctaaagctt agtttctttt
     7801 tctttatatt ttcataataa aagtttggtt ctttaatttt taaacatgac agaaaatttt
     7861 ttcttcgtta tacttgtaat agaatactat tttataacaa aggggatcga atcaatgaaa
     7921 aaaactgtta tttatactag tttatttgca gctttgtttt tagctgcttg tcaatcaaat
     7981 accaatcaag gcacatctgg gaatacgtct tccagtagcg aacagcgctc ttcacaggta
     8041 tcggactcct caacaaaagc aagcacatct tcgtctagcc agacaaaaag ttctagtgaa
     8101 gcaagtactc agtcagatat caaagtgtct gcagctcgtg cgatcgaatt gttccaagat
     8161 aaatacccag atactgcaat tactagtttg gaattagata gtgattgggg atcttacttc
     8221 tacaagatag aaggtgtcga tgatcaaaaa gaatacgaag caagaattga tgctcaaaat
     8281 gaaaaaatgg agacagagaa tccagaaact ctagatcgag atgaacaaaa tggtcaaaag
     8341 aaaaaagaag atggtctgga tgttgataaa ttgatcacga ttgaggaagc agcaaaaatc
     8401 gccgtcgaca aagtaggaag cggtacggca acagattggg atttggataa agatttaggt
     8461 actacttatt gggaagtcaa agtaaaagac ggcaatcaaa gtacatcagt caagatcaat
     8521 agccaaacag gcgaagtact gtcaactgaa caagatgatt aagaatttct tcggaaaaca
     8581 agagttgatt tttcttttag tcatgataca ctagacaaaa taacttgttt gaaggagcga
     8641 tttacttgag tttagaaacg acctttgcca atcatatctt tgccaatcct ttgatgaatg
     8701 catctggtgt ccactgcatg actacccagg aattagatga actggctcat tcagaagcag
     8761 gagcatttat cactaagagc tgtacgatca atgaacgaaa aggaaatccc gaaccacgct
     8821 attttgatgt tcctttaggg agtatcaatt ctatgggact tccaaactta ggtttttctt
     8881 attatctaga gtatgctctt gcgtatgaaa aagtgcagga aaaccaaaat caaccgttat
     8941 ttttttccat tgccgggatg agtgtccagg aaaacttgga aatgcttgag aaaatagaaa
     9001 aaagtgggtt taatgggatc actgaattaa atttatcttg tcccaatgtg cctggaaaac
     9061 cacaactagc ttacgatttt gaggccactt atgaaacact gaaagaagta ttcagcatct
     9121 tttctaagcc gctaggaatc aaattgcctc cttattttga ttttgctcat tttgatcaga
     9181 tggctgatat cttgaatcag tttccattga cctatgtcaa tgctatcaac agtgtgggca
     9241 atggtttgta tatcgataca gaacaagaag cagtagtcat caaaccaaaa gaagggttcg
     9301 gcggcattgg cggagagtat atcaagccga ctgctttggc gaatgttcgc gctttttata
     9361 cacgtttgaa accagaaatc caaatcattg gtacaggtgg gattcggaca ggacaagatg
     9421 catttgaaca tctgctatgt ggcgcaagca tgttacagat tggtaccgag cttcataaag
     9481 aagggccgga aattttttct agaatcataa aagaattaac gcagattatg tcagaaaaag
     9541 gatatacgtc aattgacgaa tttaaaggca aattacgcac catttcatag caaagagacg
     9601 aaggtcatga ttgatcttcg tcttttttta taaaaaacac tcgtctgttc attcctgtgc
     9661 aagcgtactc attgtatgtt agacgaactt gtgggaaaat aacagaggca aaaaggagga
     9721 taatatgaat gatgcaacag aattagcaaa agagcttaaa gaaaaagaat ttagttttca
     9781 agaactagtt acggatatac agaaaaaaat aaagaagcaa aatcatgaat tgaatgcgtt
     9841 tgtcgcgctt gaaccattcg agagtaattc ccacgagcta ttgattcccc agtcagaaaa
     9901 agggccattg gctggtatcc catttccttt aaaaatgctc ggtcaagaaa aaaagggatg
     9961 gctagctact tcaggatctc gtttatttga aacacaccga gcttctcata catctaatta
    10021 tgtgcggcaa gcagaagcga taggtctagt tccttttgga caaaccaatg cgccagagtt
    10081 tggtttcaaa aatattacag acccagtcat ctatggccca gcaagaaacc cttggaacct
    10141 tgaatgtaca ccgggcggat caagtggagg agctgctgct gcagtttcat caggaatcgt
    10201 tcctttagct ggtgctagtg atggcggtgg ttctattaga atacccgctt cgttttgcgg
    10261 attgattggg ctgaaacctt cgcgagggac gatgccagtt ggtccatatg cttggagagg
    10321 atggcaagga gctgctattg atttcggctt gacagtttct atgagagaca cggaggcttt
    10381 attttatggg atgagaagta tccattccgg tgcgccatat caagtatcgc cagttgagtg
    10441 gcaaacacat ccaagaaaaa aacggttgaa gatagctttt tgtgttgatt caccgatcca
    10501 ctcacagatt agtgaagagg cagtacttgc tgtaaaaaaa gctgtagatt tccttggaaa
    10561 agaagggcat gatttgacag agattcctta cccactagat ggtcgtaaac tgatcacgtc
    10621 ttattatcag atgaatggcg cagaaacagc agcaatgatc cgctcgattg aaacaggcat
    10681 ccagcgagct gtcagaaaag aagaacttga acccatttct tggactttgt tccaatatgg
    10741 tcagaagctc tctgccgcta cttacatcga ttctctgcat gtatgggatg aagcagcaat
    10801 tgtcatggaa aacctacatc aagaatacga tctattcctt tcaccaacga ctgcatttac
    10861 cgcccctaaa atcagcgaag atttgcaaag tgatgcgata agagcacaga tggaacacat
    10921 cagtgattgt tctgaagtag aaggtttaga cgttgtttct tccatgtttg aggagagctt
    10981 gaagatcaca ccttatacac agttggctaa tctgactgga caaccagcaa tcagcttgcc
    11041 tactcatttg acaaaagaaa acatgcctct aggaatccaa tttatggctg ccagaggaag
    11101 agaagatttg ctatttcaaa tcggctatct atttgaagca aatcatcagt tccatttacc
    11161 aaatccatgg aaatagcaga aacaaggaga agaagaatga agaaaaaaag attgtttgct
    11221 ctaataacta gtgccttttt tattttaagc gcttgcggta cagctgccgc taatcaggaa
    11281 gataacagct ggagtaatgt agaaaaaaag aaagaattag tagtagcgac ttctggcaca
    11341 ctgtttcccg catcttatta taatgatcaa aatgaattag ttggttatga tgtagatttg
    11401 gcaaaagagg tggctaaacg gttaaatgtc aaaatctcct ttaaagaata caacgtggat
    11461 ggacaaatca cttctgtttc aaaaagagaa tcagattttg ctgcgaacga ttttggtatc
    11521 acaaaagaaa gagaaaaaaa attctccctt tcagagactt tcaaatattc atttgacagt
    11581 atgatcgtac gaaaaaaaga tgattcagga atccactcac ttgaagatct taaagggaaa
    11641 aaagcagctg gcgaacccaa tactagctat atgcgtttag cggaaaaaca cggagctaaa
    11701 ttagtcacat atgacaatgc cacgaatgat cagtatttaa gcgatgtagc aaatggtcga
    11761 acagatgtta ttctaaatga ttattatctg cagaaaatgg ccgtatctgc tttaccagat
    11821 atccctgtaa aaatactgga gaacgtttat ttcaatgaaa acgaaagtgg ttttttattg
    11881 aaagaaggaa atgatgctct gaaaaagaaa atcgatggcg tattaaaaga gatgaaagaa
    11941 gatgggacga caaagaaaat atctgaaaaa tattttcaaa ctgatgtttc agtcaaaccg
    12001 aaagaaacga tggctgagtc ggtgagtgag tgatgtactt tcctctaatt gatttttccc
    12061 tcatgtggac ttcacttcct ttcgtactgc aaggcttggt atacacatta gggattggct
    12121 tcgtgtcgtt tcttttagga aatctggtag ggttgctttt gacagtttta ggtcttttgg
    12181 attggctgcc tctgaatgta tttattcgtt tttatttatc gttctttaga ggcattcccg
    12241 cactagtcct gctgtttctg ttatattttg ggttacctta tcaattaagt gccttaacgg
    12301 cttcagtcat ctgctttacg attaccagca gtgcatttat tggtgaaatc tatcgaggat
    12361 cactagcagg cgtttcttca ggtcagtggg acgctggttt agcttctggt ttttctttct
    12421 ttggggtatt gaaatatatc gttttgccgc aagcttttcg aatctcagta ccggcactca
    12481 gtaacgtagc tatggatcta gtgaaaggta cttcgttagc agcaacaatc acagtgccag
    12541 aaatatttca aaaagcaaag atcataggcg gtcggacatt cgattatttt tctctctata
    12601 ttttagttgc actgatttat tgggtcattt gtatcgggat cgaaaaagtg caacagtatt
    12661 tagaaaaacg ttctatgcat cagtcaatct gaaaaataga aatggtgcta gcgtggctgg
    12721 caccatttct attttttgtt tcttgtatat tctgcctagt attttaaaac catttcatgt
    12781 aaaatgtaaa tcgaaaatat gttcggaggt agaaaacatg aagaccccgc taaccatcga
    12841 aatagaatcc tcgttatacc aatattgcat cgagcaaggc ggcttggttg tagaagaagt
    12901 cacgatgcct gatgaccaag gaattgtaga tacgcttagc tgcttgacaa aatttgatgg
    12961 aagccgagaa tggcgatgct atgagctgaa agtgacaaaa gcagattttc gctctacagc
    13021 caaactgtca tttgttggac attataatta ttttgtttta ccaagtaaac tatatgaaga
    13081 agtaaaaact gaaatcccta caggaatagg tgttttagtg tatcgtccgt acacggttga
    13141 agaggagatg cctgcctctg gtacatttct gattgcgaaa aaagcagcaa agaaagagct
    13201 tgctgtaccg gaagaagctt tgacaaaccg cttcatggct tctttattca gggaagtaag
    13261 aaaagcaaag caaatggagc gaggcgtaaa atattttcca acagatcaat tgtacaaaga
    13321 attgaaaaga cgttcagaaa atcaagatcc attttctaac gaacgatatt atgaacggtt
    13381 tttagaggaa atagctagtc aggcaatcaa tgagttgcaa gaagaagtta tcgcgcttca
    13441 gcatgattat gaatatttga ggcaacaaca gcagatccgt cggttgccta cagagccatt
    13501 ggagtgaaaa atatgtacta tccttattta agaggaaaac aatttgacct attagcatta
    13561 aaagaagcac tgtcgcgagg attgctctcc aataaaatcc aaccagtgat cgaaccagta
    13621 cgtgattccg ctacgcttaa aaatgtgatc gaattatttc aaaaaaagca ccatcgaatc
    13681 gctgtgatcc aaaatcccca agtaggacaa ttcaaattat tcgatcagca tgtgcacagt
    13741 tggacagtca aagaaaatag ctctgtcgtc cctgcacaga tcttaacgcc agaaaatctc
    13801 agtgaagtac tggattcacc tccagcgttt cttgttttcg atggacagca ctacccaaaa
    13861 gatacagagg tgtggaaaca gttggcagga gttgattcga aatttttgat accagatact
    13921 agtcgctttc gcatctggct gcccgaaaac aaaattgtga tccgtgactc ttttcaaacg
    13981 agaaagcatg ttgaaagtta tgcagataaa acagatgact tttttagtga tgactatctt
    14041 tttttccacg cagacggata tattggattt tctgatttca cgatcgaagg tagccgttat
    14101 ttcgataaag ggttccctag ccgagcgctt gctatccatc taacgtatat tgatgcttac
    14161 ggcaatatac gcgtgaaaca ttttgtctct gacagtaacg actctgctaa agaccaagca
    14221 ttgaagtttc ttgaagcagg agataaaatg aaaaaatgga tcatgcgtca ccatcatcaa
    14281 ctcttgatta cttcaggaat gattgaatta ttggctcttt accagcaaca aaaattccct
    14341 ggactgggag tgttgaaaaa gtggtcactt atgcatcatt tggaacttat tagtcacctg
    14401 ctagatcatc caaaagattg gcttaaatat tattcaaaag ttcaggaact atatgaagtg
    14461 atccaatgat tagataatgt aaatgaaaaa ggaatagaaa agaggaaact ggatgtatat
    14521 tcggcaaaca aggaaagaag aagtagaaga agtggtagaa atcattaatg ccgcagcgga
    14581 tttcattgct tcgcaaggct ctcctcaatg gcaaaacggg cagaaaccaa caaaagaaac
    14641 gattttgaac gatattgaaa gaaaagaaag ctatgtatta atagtggaag atcaaattgc
    14701 tggaacagct gcattagtct caagcgtgga tcccgtttac acaaaaatag atggtagttg
    14761 gaaagaatca actggtcctt atttatcgat tcatcgtgtc gctttagcag aaagtactcg
    14821 aggaaaaaaa ctagcaaaac cgttcttaga acatttgttg acgattgcag ccagcaaaaa
    14881 tatccaagat atccgtatcg atacttatcc agctaatgaa ccgatggaaa agaccatcta
    14941 ttctgctgga ttcacttatc aagggatgat tgaatttcct tttgaacacg gcgaaagaaa
    15001 agcatatcaa ataatcatca attgactata aaatcatctg agcaaagata aagacattaa
    15061 cactactgaa aaaaacaatc atatgatagc caagaggttg taacagaagt ggccagcttc
    15121 aaaaaacaag aaagaatttc cgaaaatgct tctcaaattt ttgtggaatt ttagcgtatt
    15181 ttacgaaata gctgctttct gaaactccct tcatcgagag gtcgtgacat agcttttgtc
    15241 acgacctctc ggcttatcct acgagtatta ttcgatacat ttatatcaat aatccttttt
    15301 ttattttatc tgcagcttct tggaacgctc catcgtttga cacgactaaa agtgagggga
    15361 tagctttcaa acgtttcaac tgtgctaaat cttctacata aaccgccagt ctggctgaaa
    15421 tctgttcaga tgaatctcca cgttttttca ggcgcgattg caatgtttct ttagagatcg
    15481 taataaagat aggacggact accgtcccga aatactcata taaatgccaa aaaccatttg
    15541 ctgtcaaaac ggcgtaacaa tttcctactg tcagtttctt tttaatttct gctttactgg
    15601 aaccatattt atgttgagca tattggtccc actctgcaaa ctcatttccc ttgatcatct
    15661 gattgaatgt attgtcagaa acaaaataat aatcctcttg atctttttcc ccaggtcttg
    15721 gtgatcgatt cgtgtaagta atgatctttt gttccggctg aaaaatagct tctgcgagtg
    15781 aagtttttcc agaaccagaa ggaccgataa atacatagca ataattcatt gtcatttctc
    15841 ctttgatgat tgaacaagtg aaaaagcttt ggaaaatatt tccaaagctt ttaaaagtaa
    15901 ctttgctttt ttgtatatta taccagcaag ccagtcacaa tagcacttaa aaagctgact
    15961 aaagtcgctg ttagcaaaat tttcaatccg tgttttgcga caagatttcc tttttcttca
    16021 tttaatccct tcatcgcacc agaaatgatc ccgatagaag agaagttggc aaatgaaacg
    16081 aggaagacag atataattgc tgttgtacgc tcagtaaaat ggaaattacc atttgctaat
    16141 tctgtcatag caacaaattc atttgtaacc agtttagtcg ccatgatact accggcatcc
    16201 actgcttctt tccatgggat tccgctgatg aaggcaagag gggcaaagat gtaacctagg
    16261 atctcttgga aagtgatgcc gaatatcccg tggaagatag cattgatcat ggcaatcaaa
    16321 gcaacaaaac cgataagcat agcagcaacc gtgatcgcca catggaaacc atcaagaatg
    16381 tattctccca acatttggaa aaatgtctgt tctttgtttt cttcaatgat cagctcatct
    16441 tctttttctt ctaatacata gggatttaca attgaagcca gaatataacc gccaaataag
    16501 ttcaaaacaa gggcagtgat cacatattta gaatcgatca gtgccatata agatccgacg
    16561 atcgacatag aaactgtaga catagccgat acactcatgg tgaacaaacg tttctcagat
    16621 aggaagggta attccttttt tatggaaata aaaacttccg attgtcctaa aatagcagaa
    16681 gctactccat tataagattc caatttgccc atcccgttga ttttacttaa tcctagacca
    16741 acagctttca taaataatgg aagaatcttg atatagcgta gaataccgat aatagcagaa
    16801 ataaatacaa ttggcatcaa tacggaaaga aagaaaggtg cacttccttt atttgctaca
    16861 ccggcaaaaa caaagtcaac accttgccca gcaaaagcaa gaagatgatc aaacattttt
    16921 gccaatacag aaacaaccgc tgtaccaaaa gttgtacgta ataatacgaa accaagaaca
    16981 agctgtaaaa cgaacatcac aattagtggt ttcaatttga ttgctttttt gttactgctg
    17041 atcaaaaaag caagccctaa tgtgacaaat aaaccaataa tacctaataa ataactcaaa
    17101 taatcactcc tattccaaat tccgttttat tttacctgtt ttgcaaataa aatactaatc
    17161 tttagtgaaa ttttcattac ttttttagag tgaaacgcat tcattttcca ttagaaaata
    17221 aagcgaacaa aataaaaggt ttaaaaagtg taacgtctta gtaaagtcta taaaaaaacg
    17281 aaactatcga ttaagctaat agtttcgttt tcaacattta taagtaaact ttttctattg
    17341 gtaatataga ttttcggaag ggtagacagg tgcgcaggta atatcgattc ctagtttttt
    17401 caatgtttgt tcatcatttt tattgaccat cacagtagag tgggcttgtg ctccctcaag
    17461 ttcagctagt ttatcataag caacttgagc gattggattc gttactgcac tgattgataa
    17521 agcgatcaag acttcattga tgcttagtgc atccaaagag gaatgaagtg tctttgattt
    17581 caatccttgt attgtttcaa gaactaatgg tgacaataaa ggaatgtcat ctgcgatatg
    17641 ggctaaatgt tttactgcat ttaagataac tgccgctgac gcatccatca atgaacttgt
    17701 acgcccggta atgatgactt catctggtaa ttcgattgca atcacagcag aaggatcttt
    17761 tgtaggactt tgcgcttgaa tcttatctgc atagtcatgg gcagggacta ccacgtttcg
    17821 gtcttcagga cgtaaaccga cttcttccat aatcagtttg attcgattaa ctgcttcttc
    17881 gtcgatcaat ccttttttga agtcgcattc tgtttggaaa taacgacgga tgatttcttg
    17941 tttagaggct tcttggacaa cggtatcatc cacgatccca aatcctacac gattcacacc
    18001 catgtcagta ggagattgat aaacagattc tttaccagta attttttcaa taatacgttt
    18061 gattacagga aatgtctcaa catcccgatt atagttcaca gctactttat tgtaggcatc
    18121 aaagtggaag gaatcgatca tattgacatc ttttagatcg actgtggctg cttcataagc
    18181 aatgttcagc ggatgtttca acggaacatt ccatactggg aaagtttcga acttggagta
    18241 accagctgca tgtccttttt ggctttcatg atacagttgg ttcaaggaag tagcgagctt
    18301 tccacttcct gggccaggag ctgtcactac aacgattggt ttagttgttt caatatactc
    18361 attttttcca aaaccatctt ctgagacgat tttttctacg ttgactggat agtcttcgat
    18421 ttctgagtgt ttatagacct tgatgtttcg tctttctagt ttattgataa agactttcgt
    18481 ggcaggctgt ccactatagc gagtgataac gacactgttg attaataagc cataaccacg
    18541 taattcatcg attaaccgca agatatccat atcataagta atcccataat caccacggat
    18601 cttattacgt tcaatatctc cagcatagac gcaaatcagt atttcagctt gatctttcaa
    18661 tttttgcagc aatttgattt tcgcatcttc ttcaaatcct ggaagtacac gtttcgcatg
    18721 cttgtcgtca actagcttcc caccaaattc taaatataat ttgtcatagt ggttcactcg
    18781 ttccaaaata tacgctgact gctcttcaat atatttttct gaatcaaaac caattttttt
    18841 cactaggttc cctccttaag tactaaagca ttttttcatt tttttgagga ttcgtcaact
    18901 ggaagagcga aattcctcaa aaaaacaaag aaaatggttt aaaccaactt gtctagatag
    18961 ttattcattg gtatgatagt ttttgataag gaaggtgcta catgaaaaaa agacagaaaa
    19021 agaaaaacgc atataaacac tatatccgtt cgatttttac cggttatgaa agaatgcttg
    19081 aagatcccga attggaacaa ttgacgttta cttatctaaa cgaagaaacg cagctaactc
    19141 gtgatgagca tcagcgcatt catttcacaa caagagatct gcctagtaaa taaaaaataa
    19201 gataaaggtc atcggattcg attctgtcct atcagatgga aagactagtt gatcgaaaaa
    19261 aaggctgtac caaattttgg tgcagcctgt tttatggagc attgcccgct cttttttata
    19321 acaatttttt acagaaaatg gtactattga agtattaata agtgaaaaac agatgagtaa
    19381 gaggaggcaa gtagtatgaa agagccagat acaaatgcaa attatgagcc agacgaacta
    19441 gaggagacga atgcggatca ggatacagga caagaatcgt cttcttttta cgatatcaaa
    19501 gaaaaagcaa gcatgaatct ttcccaatta ttagaagact tacaggcttt tgaaaaagct
    19561 gtccgcgaag aagatatccc tgagatctac cgtttataca atggccgatt gaatgaagaa
    19621 ttaaaaagaa gctcaaatga aaatcacgag atcgatcaat tgctgatgcg taagatccat
    19681 gatcgttttt tacaggaatt tccttttatg gaacaagtag aaaacatctc gccaacgatg
    19741 agctattaca aaatcggcac ttattaccat gatcggccca cggtcggtat tgatgcaagt
    19801 ctgccagaaa tttttgtttt gcctaagatc gatgaagagt gggagaaata ttcccaaccg
    19861 gagtcaacgg actatgacaa aaaaatcaat gagctagacg caaaggtgat cactgctcag
    19921 acagaaattg aacgtttaga tgaacaaata aaagaaatca atcgacaaat gactgatttg
    19981 aacgacaata aaggattctt gaatcgtaaa aaaatcgagg aagaaattca agaattagag
    20041 aagaagaagc aagtactatc taatgaaaaa ttaggctggc ttccttatat tgagacgcct
    20101 gaaacaatcc agcagcaaaa agaagcattg aagcaagaag caagagcaga ccagcttcgt
    20161 gcagccatcg tagaaaaaga acaaaggcaa atcagacgct atttcggtag caaagaggga
    20221 ttcggtcaag caatccatga attcttgatg aattatcttg gcaatgagaa tcctaataat
    20281 caatctaatg aaggaggttc cgagtatgaa tgaacacgat gaagcagaat ggacaaaaaa
    20341 tgaagaacaa acagaagatc atgaagaaac gaacacttca ttggaagaac aaacaagtaa
    20401 tcctctggat gacacagaag aaatccctat gctagaggaa acaaaaatac acgaaaaaga
    20461 aaaagtaact ccgacgaata cgaatactgc agaaaacacc catgcttacg aaataactga
    20521 aaatcccggg tatttagaag gaaaagagca agatcatcaa gatatcgtca gtttgattga
    20581 aacagcggaa gcagaattag cggatttacg tatgagaaaa gatttgatcg aatcagattt
    20641 tccacaatta ttagaatcat atgatcgttt tatattgaat gaagaaccaa tctccacgat
    20701 cggaaagaca agcctgatcg aatacttcac gtatgaatta ctgaaaccgt tgaatgatat
    20761 tggtctggaa cggtcaaatt cagcttatga cacatggaaa acaagacatt tttcgatcaa
    20821 ttatacgttg aatggacaaa acgaattagt cttttccttt gtattaccga ccatcgatca
    20881 acgataccaa gtggaatcga tgagtctcct aaacgtatca ccagagacaa tggaaatcaa
    20941 tgtccaagat gaccgggtgc tttctttgat ccgacactgg tcagtggatc gagtattctc
    21001 tgcagggcag atcacgatat tcaatcacaa attgaatcaa ttattagccc atgcaagaac
    21061 acttggtttt accgttaatc agacattact agacaatacg aagccacttc gtttgaatct
    21121 tcagagcgaa tttgaattga cgaatgaagt attggatgat atttttatcg tggcaatgaa
    21181 aaatccatcc tacgatatgg aaaagatcaa cgaaactact tatcaagtac gattagataa
    21241 aggacagtct ttaacgataa caacaaacga aaaagatcaa acagtcttgt cgatctcatc
    21301 tggagactac ccacgatctg tcattgattt ctttatcaat tacgaattct tggtcccatt
    21361 aatggtgaga aagtcctgat tggataagtt ggattaccag atgtcattca gataattctg
    21421 ttccaaaaga cttgcggcag ttatccagaa taattgtcac aagtcttttc tgtatgtact
    21481 aaatggacgt gaataacttg ctgatgaagg agggatttca ttaggaatgt ccacaaataa
    21541 aatagcacag cttagcttat tgtctgctgc ttgtgtagca ggtaggatcg cttttcaatt
    21601 tattccgaat ttccagccaa tgactgctat ttttttattt atagtacttt acttaagctt
    21661 aaaagatgcg ttaattgtca tgagtctttc tattgcgatc agcagttttt attttggtgt
    21721 tggaccatgg gtcatcggcc aatggatcag ctatactgtt gttctgagtt tgttttcaat
    21781 cgtctgcttg agaaaaacag tgcaaaggaa tctatggtta aagggagtct gtttttttct
    21841 ggcgggcatg gtttacggaa taggtatgac cgtttttgat acgctgttat atcgtttgcc
    21901 tcaaccttgg atctattacc ttcaaggggt gtcgtttgat ttgatgcaca gtataggcaa
    21961 tgttgtgttc tttcttgttt ttctgccagt cgtcaaacgt ttttacaatc attcaggagg
    22021 aaaaaatgaa aaaaataatt tatagtttgc ttgcaatgag tgtcagtata ctcattttga
    22081 caagttgcag tacaacctat acacaatcgg cttccaacca aaaggaggaa gtaaaaacat
    22141 cgcaaaaagc aacaatcacg ttacaagaaa atggtcaaaa cttttcggaa aaagaagtgt
    22201 tcttcaaaaa aggcgatgat ttactgagta ttttgaaacg aaattttgaa gtcaaagaag
    22261 ataacggctt catcacttcg cttgaagggc actcacagga tgagaaaaat caactctatt
    22321 ggatgtttac tgtggacggg aaaagtgcta ctactggtgc caaagagatc aaattgaatg
    22381 atggacaatc ggtcattttc aatttgtcta aactataagt ttcataaaaa actgttaaag
    22441 ggcgaatatt gccataattc agtgagttca gttgatgaaa gaaggaaaat aacatggaaa
    22501 attttaaaaa aagcggaatg ttttccgtaa ttgctgctct aggggctaat attctagttg
    22561 ctatcagcaa atttgtcggc tatgcaatca gtggcagtgc cgccatgcta aacgaaagca
    22621 tccacagtat cgttgattgc agcaatcaga ttttgctgtt attcggtgat aaacaagcca
    22681 ataaaggaca gagcgagttg catcaatttg gtgaaggacg agcaaaatac tttttcagta
    22741 caatcgtcgc aatgatgctt ttcttcggcg gtggggcact tggggtgatg gaagcttttg
    22801 aaaagttgac gcatccatcc catgaagtgg gtaatccgat cattgttata gcaatactgt
    22861 tatttggttt ggtaatcgaa ggaagttcgt tacgcgtggc aatgaaagaa atcaaagaat
    22921 tgaatactga aaaactttcc acgatgcgct ttttgcgcga aagtcgacac agtgaaatac
    22981 tgattatttt tacggaagac ttgtgtgctg taatcggttt ggtcttggct ttagcaggaa
    23041 caatattgac ttatgcaacc gggattgctg catttgatgc gatcagcgga ttgctgatcg
    23101 gtttcttgct gatgggagcc gccattttcc tagcaaaaga attttatagt ctgatcatcg
    23161 gtgaaagcgt gacagcaagc gatttatcaa aaatcaagtt agcttttgaa cgtcctgaga
    23221 tcagtcggct gatcgatata aaaacagttc atttaagtcc aacggagatt ttagttgcag
    23281 caaaagcaga tatcgttggt aacaaagaga atgaagctta ctcggtcatc aatgatattg
    23341 aaaaaaatat gcgtcagtct cttcctgaca agaagatgta tatatacatt gaaacagata
    23401 aatatgaccc aaattattct cgtaaataaa acgtttattc atgaattgaa gcaaaaatga
    23461 gaaaaatata atcttgtttt taaataaaac ggctacaatt tagcgaattt atgttacaat
    23521 gagtccgctg tttatttgtt gtaattaaag gagatatttt aatgaacaaa aagaaaagtg
    23581 cgccatggct tcaagctttg catgcagtga tgccactttg tataagctat ataccagtag
    23641 gattagcttg cggagtattg ttgcaaaaag ttggatttga tcctctctta tcaggactgt
    23701 tatcgattct ggtcttttcc ggtggcgcgc agtttttagt tgcatctatg cttacgacgc
    23761 aagcatcatt tgcaacgaca ttattgatgg ttttcttttt agaattacgc tatacattat
    23821 taggagcaag tcttgccggt tttatgaaaa aagaaaagcg gacgtttttg gctgtctttt
    23881 ctcaatcact gaatgatgaa aactatgcgg tgaactactt aaagttttca actgaccctt
    23941 cctggaataa aagaaaggct ttatatgtca attggttctc aatgactgca tgggccggta
    24001 gcaatatgat cggtaatttt ttcggctcgg tgattcgagt agatgctgac cttgtccatt
    24061 ttgctttgac ggccatgttc attttcatgt ttatcatgca gatgaaaagc gcactactga
    24121 tctttacagg tttattctca ggcgtattag gggtcgtatt catggtatta ttccaaaata
    24181 ctttcggatt gattgcagca acagtcattg cttcatttgc cggatttatg ctggagaagg
    24241 cattcaaaaa agaaaaagct aagaaactaa gagaccgcgg taaagatgtc aatgagccgc
    24301 tcttcaactt cccggaacag gaggccaatc accatgacta aactatattt gctactttta
    24361 gttgcttgtc tgttcatcgt ggcatatatc ccgcgcttgt tcccgatgct ttattttact
    24421 catcgaaaag tgccatcctg gttcagtgac tggatgaaat atgtaccggt ggcattattt
    24481 gcggcgttag cttttaaaga tgttttcatt actcatgaac atctggatat tgcttggaat
    24541 atcaaaatag ctgcaatgat tctagtagca ggcgtggctt acaaaacacg ttcgatggcg
    24601 ttgtcagttt tgacaggact tgcgtctgtc tttttgctgt ctatgcttta aactgtttta
    24661 ttttattaaa aacagagatt gcgacataag ttgttcaaac tgatctatcc gaactgcatt
    24721 tgcaacagtc aattctggat gcaagtttat tcgtagggat aaaaaagatt agtgttggct
    24781 tatgatgcaa gctctttttt attttaggaa ttagagaggg atttgtcctt ctatgatttt
    24841 ttgctataat agggaagatg tttattttat gaaagaatag ttgagggaat ttaaatgaat
    24901 aaaaaattga tgcaaggaac attttggcta acctttgcta atcttctatg taaagtttta
    24961 ggggtagtct atttgattcc ctggctaagt atgatgggga acaatcaaga tggtatgctt
    25021 gctacgacat tgtataatgt tggctatctt ccttatggat tgttcctgat gcttggtaca
    25081 gtcggatttc caaatgcgat tgcaaaaaaa gtagctgtag ccacaaaaga aggagataac
    25141 gctgcttgtc ggctgatttt tagaagtacg atcaatatca tgtttgtcat cggtatcgcc
    25201 tctgctgcac tgatgtattt atttgctcct ttactagccg gaatcagtcc gattgctaac
    25261 gttaataatg ggatactagc tatcagaagt ttatgcccat ctttgattgc tatcccaatt
    25321 cttagtgcaa tgagaggata tttccaagga aaaaatgatc tgcggcctta tggaacttct
    25381 ttgattatcg aacaggctgt gcgagtgatc gttatcttgg ctggtactta ttacttgcgc
    25441 gtattgactg acggaaccat attagaagct gtattgatca gtacagtcgc ttctttcttc
    25501 ggtgggttag ctgcgattat ccatatgtat atcgtcggac gcagaaaaga cttcttcgaa
    25561 cttaaagatt ttttgatttc cagccgttat ttcgaaagag aaaaccgatc tgcctctgtc
    25621 tctatcattc gggaaacact accgtttatt tttgtcggct cagtcattac tatcgttcaa
    25681 atgatcgacc aagtaacgat gaaaccactg cttcactttt tccgtccaga gatcgcagat
    25741 cagcaactgg aattcttatt cagccgtgct tctgtcaatc caaataaatt gacattgatc
    25801 ctgatctcca tggtaggaac agtagctata agcagcttgc caatattaag cacgatgaag
    25861 aaaaaagatc ggatacaaat cgaaaaaaca gtaggagata gtttttcgat tgcgttattg
    25921 attcttcttc cttcattgac tggaatgtct ttattagctg gaccactata cacattgttt
    25981 tttggctatg atcctgaaag tgtcggatat ttccaaatgg ctttgctagc ttctttgttt
    26041 ttctctttat tcacgatcct atctacgatg cttcaatctt tgaatcacca tcgttttgcg
    26101 atccgattaa ctgtagaagc aattatcctg aaagtcatct tccaagtaat cggattagga
    26161 ttagttggcg gatacgggat gagcttatca aatggcttag cattcggtat tgtctttgtt
    26221 cgcggctatc actttatgtg caaagaatac cgaatagcac ctttagcaaa gatcagcaat
    26281 tttttcttaa aaactttccg ctccaccctg attatgcttg cagtatgttt tgccgttttc
    26341 tttttgctga atcagcgatt gtcaatggaa tcaaaaagct atgcaatgat ttattgtgtg
    26401 gctgtaggaa gtattggcgg cttagtattt ttattttctc aattcggaaa aaatgggttt
    26461 cgaatgttga aaaatgttaa acatcatagc agaagcaaag aataggttaa ctaatcgttt
    26521 tttgctgtca cttgaaaaac ggcaactcgt atgattacgc ttgtcgtttt tctattttcc
    26581 aattttagtt tcatatctaa tcttacttat gatatagtta taaggtctgg aaaaattctt
    26641 tgaaacgagg aaattaaaca catgaaactt gcagtagtta cagatagttc ggcatatctg
    26701 ccggaacgta tcaagaacca tcccgactta ttcgttattc caatcccttt gattatggat
    26761 gggaaaattt ataacgaagg aatcgatatc gaagcggatg aatattatgg acttttaaaa
    26821 aacagtaaag attttcctac tacttcacaa cctgtcgtag gggaagtttt gggtttatat
    26881 gaggaattga aagagaaagg gtatgacacg attttaagta tccatctttc ttcagggatt
    26941 tctggctttg tcaacacatt atttgcgatg aaagatgaca tcagcggagt aacggtcatt
    27001 ccttatgact ctaagatcac tagtatgccg atgggacaca tggtagaagc tgccttagac
    27061 ttaaatgatg aaggtcagtc ccttgatgaa atacttgcac atatcgatcg aatccgagat
    27121 aatacctacg cttatctgat tgtagatgat ttgaacaatt tagtacgagg aggacgtttg
    27181 acaaatggtg cagcgctgat tggcagctta ttaaaaatca aaccgatcct gacattttct
    27241 gaagggaaaa ttgttttatt cgaaaaaatc cgttcaagta aaaaagcatt tgctcgagct
    27301 gaagaaatta ttggtagaag aaataacgaa atacaaccgc cagtcaaact ttacgtgata
    27361 catgcaaata atttagaagt agcgattgcg gagaaagaga aattgcagaa aaaatatcca
    27421 aatgcagaaa tcgaaattgg tcatttcgga ccagtcattg gtacacattt aggtgaaaaa
    27481 gccatcggca ttgccatttc agcgcaataa ttccttttat tcaaaaaaca taccaaaaat
    27541 attccaacat catcttggac tttctacatg ttactaatga gcgtgtaaaa gaacgagatg
    27601 gtgtttttat ttctatcaat gaagctcttt ttctttgcaa tcctcacttc aatcctctat
    27661 aatgtcgcat atagtttagt aaatgagtaa actactaatt tacttattta ctaaaaataa
    27721 aaggatgagg agttaaaata atggaaatac caacaaattt aaaacataaa ccagtaatcg
    27781 ttgtagaaga ctatgataaa gttgatggaa gaaatgcatt aaatacggat gcaaaagggc
    27841 tttcactggg ccttgctcag tggaatgatc gtggaaaagt cgatatctca ggcaaggtat
    27901 ggcgacatac tggagaaaaa tggtcacgac agtcggaaga attaccaatc acacgtattt
    27961 tagatttagc gatcttagct gcacaaggaa gtttatactt ccaagatgct tatcgttatg
    28021 aaaaatttta tgatccagaa aatccagtcg tagacatcat tggattacaa gggaaccgaa
    28081 tgacggtaga agtagatacc aaaaatccaa agatcgatga agacatcatt ttgtattacg
    28141 atacactaca aaaagacgga gaactgattg gggaacgatt ccgtatttta aaacgtcttt
    28201 tagatgagct aggatattaa tagacagaga tgatcaaaag gggaagagaa gcatggagaa
    28261 tttctcacta acagaaaacc gaaccttttc acggctagaa aagcaaatga tctggaagaa
    28321 accgaaaagc catcggacaa gtgcagaaga atggcggatc gcctccgaaa tcaaagggaa
    28381 ttggcaagat cctgaaatga aaatcagtaa cgtacttttg gaaggagatg ccgggtcggg
    28441 gaagacacaa ttagccaaag cactatctgc tgatctgcaa cttccctata caaaagtgac
    28501 ctgttttgca gatatggaca aatcagatgt tttcggagcc ttattacctg tagtagattc
    28561 taataaggaa caagaccaag aattactaga agctatttac caaacagata cacttgaagc
    28621 tgtactgaca ctgatccaga accattacgg cattgatcct ttttctgcta aagaaaaatt
    28681 agcagagcta gttcaaagga tcgaagctga ttatccagat gcaatccatt acagctatta
    28741 cccttctgaa atcgttcgag cgattgaaaa aggatattta ttagagattc aagagccgac
    28801 tgtcatccga gatgcctctg ttcttgtggc acttaactca gcgctcgaac caaatgggat
    28861 gttgaattta ccgacaggaa tcattcgtcg ccatccagat tgcgtcattg tgatcactac
    28921 aaatcgaaat taccaaggaa atcgcccatt aaatgaatct ttaagagatc ggatgcaaca
    28981 tgcggaaaaa atggatcttc ctgccttaga agtcatggca gaacgtgcga tggcgaaaac
    29041 tatgatccaa aaacaagaac ttctcttaaa gatggcagag attatccgtt tgttggatga
    29101 aactgcaaaa gctaacgcca tcaaaggtgt agcaggaatg cgttcttatt tttattgggc
    29161 aaatacctat aagcaaggac aagatttact ccagtcgatt tatccaaaag ttttgtataa
    29221 attatccact gattcagatg aattggcaat tcttgaacaa gctttgtctg acagtggatt
    29281 gctactggaa cttcaggaca tattgagaaa agaaaaatgg ggtcatcctc aatctgagca
    29341 tacaaaagga agaaccatta gcgccgaaga agcaaatgaa cgaaacatca ctgaaaatgc
    29401 tgaagaaatt ctgcgcttag atgaaaagaa atcgttgtct gctgaagaac caaatgaggg
    29461 agaagagaaa caagaagaaa caatagaaaa aaacgagatt cctcctcaaa tgcaaaaaga
    29521 acgcagtagc gatatcgaag gaaaaaatca aaaagaacaa caaacaggag atgattctca
    29581 agaaatgtct gcttctgaca tggaagcaca tgataaggaa atcaagaagc aactgaataa
    29641 agaagcgcga caaatcatga aggaaacgat tcatgaaaaa gaaggtctca tcgttcaccg
    29701 accagctttc caaggaaaaa cgccggaagc acgtgagcta cacatgcaag taatgccaat
    29761 agtagaatca cttagccggc aaattttaga gttactggat aatgaacaaa cagagacgta
    29821 ccaaaaagga aaatacgaag gtcagcggtt caatgcaagc aaagtagcat atggtgattt
    29881 gagaaatttt gacaaaaaga acccgccaca tgagcaacct tctttagcgg tagctgtacg
    29941 gatcgatgaa tctgggtcaa tgatacggga tgatcggatc gaagcggcaa aaaaagcagc
    30001 gattgccatt gccgaatttt ctaagaaagt cgatatccca ttgttgattt acggagatac
    30061 agcagaccgt tcgtcaagag aaaagacttc tttgttttct tataaagaat ttgaagacgg
    30121 atttcaatgg ttaaatgaaa aattagtcac tatgaaacca aggcaaaaca atcgtgatgg
    30181 tgctgcactt cgtttagcag cagaaaaatt aaacagacaa tccgcaacaa ccaaactgtt
    30241 gcttaatatt agtgacggtc agccaaaagc gttgccggat tatacaggca aaaaagcaaa
    30301 agaagatatc cagtctgttt tgaaagaata tgaacgtcaa ggaatcctat ttgtctccgc
    30361 agctattggc caagacaaag aagaaatcaa gtcgatctac ggtgaaagtc gttttgtaga
    30421 tattactgac ttgaatgaat ttcccaagca aatgattcaa ctgattgccc gctatctatg
    30481 ataaaataaa gctcaacgaa cgcacttagc agattcgttg agcttttcgt ttctagttac
    30541 cggtaacaag gatacttcta aaatagaatc ggttataatc aagagggacc gttaaaggag
    30601 tgaaacgata tgatacaaga acaaaaatgg tggaaagaag cagtaggcta tcaaatctat
    30661 cctgctagtt tcaaagatag caatggcgat ggtcaaggag acatcaatgg gatccgtgaa
    30721 aaacttaatt atttgaaaga tcttggtatc ggctttatct ggatcaatcc gatctatcaa
    30781 tctccatttg tcgataatgg ttatgacgta agtgactatc aagatataga agagagattc
    30841 ggaacgatgg aagattttga tttattgcta aaagaagcac atgaattagg gatcaaagtg
    30901 attatggatc ttgtcatcaa ccatagttcg gatcagcatc aatggtttga agaatcgaaa
    30961 aaatctaaag aaagcccgta tcgcgattat tacatttggg tcgacggggt agatggcaaa
    31021 gaaccgaata attggacatc gattttcggc ggttctgctt gggagtattc tcatgaaact
    31081 ggacagtatt atctgcatgt ttttgcaaaa gaacaaccag acttaaattg ggaaagcgag
    31141 aaattgaaag aagaactatt caatatgatc cgatggtggt tggataaagg gatagatgga
    31201 tttcgtttag atgcgatttc tcatgtaaaa aaagatgaat attcagtaaa agccacagag
    31261 aaccctttct caccctttca aaatgtctca ggaatcgaag aacatttgac cgatttgaaa
    31321 catgtttttg aagagtacga tatcatgact gtcggagaag caagtggtgt cactgcagaa
    31381 gaaggaccac aatgggtagg gaaagacggt tatttcgata tgatattcga atttgatcat
    31441 atccatatct ggcagcaaga aaaagaaggg caattagatg tccttaaatt gaaacttgca
    31501 ttaagcgctt ggcaaacttc attggatggt atcggatgga acgctttata tatggaaaac
    31561 catgatgttc ctcgtgccgt ttcagtgttt ggagatactc gtcccgattt ttgggctatg
    31621 tctgcaaaag caatcgctat gatgtatttc tttttgcaag gtacgccatt tatttatcaa
    31681 ggacaggaaa tcggaatgac gaatatgccc tttgaatcga tcgatcaagt tgatgcagta
    31741 gattcgaaaa gactttataa aaggctgctt gcggaaggta agacaagaga agaagcattg
    31801 gatatcattc gtgaaacaac gagagacaac agcaggacac ccatgcaatg gacttcggaa
    31861 caatatgctg gtttttctac acatgaacct tggctgatca ctaatccaaa taccaaaacg
    31921 atcaatgtag aacaacaaga atatgaacca gagtcggtcc tgcaattcta taagaacatg
    31981 atccgcatta gacaaaccaa taaaggtctg atatacggtt cttataaaga atatcttcat
    32041 gaacatccac aactttatgt ctatgaaaga tatttagaag atgaacaata tcttattatg
    32101 gtaaacttaa cagaatcact tgctgactat gaacttccaa aagaagcaga tcagtcctgg
    32161 acattactct tgtcaaattc ctctagcgga gaatttgaag ctaaaggcat actagcacct
    32221 tatgaagctc ggttatataa aacaaacaag taaaacttcc tcgttaaagt tcattagttg
    32281 gactttgcga ggaagttttt cagattgctc tgtcaattac tcatttcaat aattcgctct
    32341 aggaccaccg atatatttag gacgagagcg aagggctgtc acgtgagctt gtccaagggt
    32401 tttcaaacga ggtctgacag gtacttggac atgtttgata tgcataccga ttgatgtgtc
    32461 accgatatcg ataccggctt gtccaactac gtgttccact tcgacaggat cattgaactg
    32521 gtcaaaagca gcaacagaac aagcacctcc agcatgtagt gcaggaacaa cagagacaat
    32581 ttcgaaattt tttgcttctg ccactgttcg ttctactact aatgctcggt tcaaatgttc
    32641 acaaccttgg acagctagcg caatttcttt aggatccaac aactctttta acgtacggat
    32701 gatccattga ccaacttccg cactggaatt ttttccaata tgtcctccaa cgacttcgct
    32761 tgtgctgcat cctaaaacaa aaagatcacc ttttttcaag tgtgcctcag ccaatatgtc
    32821 attaactatt tcagtcaatt ggtcttttaa ttctttttct gacaacttca ttttctaaaa
    32881 ccttcttttt caattaatat tgcttccgtg cttgaatacg ttgaagactt gcagttatag
    32941 gaaaggcaag tcccattcca atcagatttt ggaagatgtt tcctggtata gaagccactc
    33001 cagccggcca atcatataaa atccaaccgg cgataccata gccgatgatc ataactaagc
    33061 ttcctaataa aagccctaat ccccacatac gagtagaaga tttgctgaaa gaaccagcaa
    33121 catatccttg taacccgtgg atcactaatg aaaaaactgc ccactgcgga tatcctgaaa
    33181 tcaaatcgat caatagacca ctggaagcac caacaactaa tccacccgtt ggaccataaa
    33241 gaaaagcagc ggtatagatc ccggcctcgc ataatgtcac aaatccattc gtagccggta
    33301 cagggatcaa aattgttaat gaaagggcaa ctgtcaacgc aatcagcata gcatagatcg
    33361 ttaattgctt agttttcatt tctcattcct cctttttgaa taccgccaga ccagacactt
    33421 ccggtatgat cgttcatcag cacgccatta gaaatacaat gggcaacaaa ttttttactt
    33481 tctgctactg ctttggtaaa atctgcccct aacacaagat tcgctgttat tgcagaagaa
    33541 aaggcacaac cggccccgtt tactgttgta gtgtcgattt ttttatgaga aaatacctca
    33601 taatgatcaa ttgaatagag aagatccaca gcttcatctc cagccatcct tgtgccgcct
    33661 ttgatcacaa tgttttttgt tcctgaagca gtgagttctt tagcgagatg gatcatttct
    33721 gttaacgaag agggaagagc ttgaccagaa agtaaagcag cttctgccaa attaggcgta
    33781 atcatcgtaa caagtggaaa aagttcttcg atgagctgcg aaatatacaa ttgattgatc
    33841 acagcttcag tttctttgaa tgccaaaaca gggtctaaaa tgattgggat attttgtttt
    33901 gtttttatga agtctcgaac aaccatgatt gcttcacttg aattcaataa cccaattttg
    33961 ataccatcta atgaagtcat tttatcaatc gaaactaact gtcgtttaag caattccaaa
    34021 gatatagatt ccagcataaa tcgctcatta atatctagtg cccctataga agtcaaggcg
    34081 cttagtccga atagaccaaa attctcaaaa gtttttaaat ctgtttggat tcctccacca
    34141 gcaaatggat cagaaccgcc aattgtcaag attcttttca taacattttc ctccatgaat
    34201 aagagtataa cgaaattttc aaaaaagaaa aacagccaat tggcatattt ttatctcatc
    34261 caatttaaaa aaacaaaaag aaaagaaaga ccaaaatgga tctttctttc cttaaatagt
    34321 taggactttt gtgattttaa ttctttctcg atttgaagcc gttgcacttt cattgtagct
    34381 gttcgcggga ttgcatcaaa atcacggatg atagggacgt tcaagcgagg aagttcatgg
    34441 acttgctccc accatcgatt ccaatccatt tctttatcag gagctaaagc aataatcggt
    34501 tgtggagaat gatttttatc ccttacaatc actacttctg ccaaaaaatc taacgaatct
    34561 aataaaaagt cttcaatagc taatgtacta ttgatcgttt cgatcaaatc cacttgccga
    34621 tctttcaaaa ataggtggcc atgcttatcc ataaaaccgt aatctccgct atcccaccaa
    34681 tcgccataaa cattttcctg gaaccgtgca tcttccttgt aataagtcaa agcccgtcct
    34741 ttagacagta attgtatatg accatctgtg ttttcaggta ggacattccc aactgaatct
    34801 gtaatccgag cgcttgtcat gtcttccagt ccaacgccca tatctcttgc atcacttgtt
    34861 ttcaaactct ctagtgtatg agccttaaga atcattggtc cgcattcact ttggccatat
    34921 acttgaagaa ataccgcatc ctgtgccatc gacgttcgca aaaatgtctt cattgtctgg
    34981 ttgtttatag catcaaaagt ggagtgatag tatcggatac ccgaaaaagc ttctggatgc
    35041 tccttagcag taaaacgcca ctgaacaaag ttattcggat gggtctctag tgcaattggc
    35101 cggtgagctt ccaacatatg aacaactttt gaactttgtg cgtttgctaa aggcatcata
    35161 ggaaatccca tggacatcaa agaagagata ccaatattga atctggaatg cactggagag
    35221 atgtgaaaag cgattaattt cttttccgaa atttttgtga aaactgtttt ttgccatttc
    35281 gtccgccatc ccatagaatg agcagaatga caaataagtt tagggatacc agttgtacca
    35341 gaagtatggg tcatataaga aatttcattt ttgtctaaaa atgattgaga aacagacaaa
    35401 gcaggttgtt ccattaaata aagaatagg
//
LOCUS       DAFEEZ010000024        34769 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000024
VERSION     DAFEEZ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.024"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            160..840
                     /locus_tag="LP245_001266"
     CDS             160..840
                     /locus_tag="LP245_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL1519196.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            930..1964
                     /locus_tag="LP245_001267"
     CDS             930..1964
                     /locus_tag="LP245_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBL1519197.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1978..2313
                     /locus_tag="LP245_001268"
     CDS             1978..2313
                     /locus_tag="LP245_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519198.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2297..4777
                     /locus_tag="LP245_001269"
     CDS             2297..4777
                     /locus_tag="LP245_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519199.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4833..6392
                     /locus_tag="LP245_001270"
     CDS             4833..6392
                     /locus_tag="LP245_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1519200.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6389..7753
                     /locus_tag="LP245_001271"
     CDS             6389..7753
                     /locus_tag="LP245_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1519201.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7924..8994
                     /locus_tag="LP245_001272"
     CDS             7924..8994
                     /locus_tag="LP245_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1519202.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9009..9677
                     /locus_tag="LP245_001273"
     CDS             9009..9677
                     /locus_tag="LP245_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519203.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9697..10275
                     /locus_tag="LP245_001274"
     CDS             9697..10275
                     /locus_tag="LP245_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1519204.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10676..11587
                     /locus_tag="LP245_001275"
     CDS             10676..11587
                     /locus_tag="LP245_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL1519205.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11965..12882)
                     /locus_tag="LP245_001276"
     CDS             complement(11965..12882)
                     /locus_tag="LP245_001276"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBL1519206.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13084..13521
                     /gene="zapA"
                     /locus_tag="LP245_001277"
     CDS             13084..13521
                     /gene="zapA"
                     /locus_tag="LP245_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBL1519207.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13579..14127
                     /locus_tag="LP245_001278"
     CDS             13579..14127
                     /locus_tag="LP245_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBL1519208.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14242..16602
                     /locus_tag="LP245_001279"
     CDS             14242..16602
                     /locus_tag="LP245_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBL1519209.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16689..17003
                     /gene="trxA"
                     /locus_tag="LP245_001280"
     CDS             16689..17003
                     /gene="trxA"
                     /locus_tag="LP245_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBL1519210.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17185..18963
                     /gene="uvrC"
                     /locus_tag="LP245_001281"
     CDS             17185..18963
                     /gene="uvrC"
                     /locus_tag="LP245_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBL1519211.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19108..20007
                     /locus_tag="LP245_001282"
     CDS             19108..20007
                     /locus_tag="LP245_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519212.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            20000..21262
                     /locus_tag="LP245_001283"
     CDS             20000..21262
                     /locus_tag="LP245_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1519213.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21423..23321
                     /locus_tag="LP245_001284"
     CDS             21423..23321
                     /locus_tag="LP245_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBL1519214.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23651..24370)
                     /locus_tag="LP245_001285"
     CDS             complement(23651..24370)
                     /locus_tag="LP245_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBL1519215.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            24707..25039
                     /locus_tag="LP245_001286"
     CDS             24707..25039
                     /locus_tag="LP245_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519216.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25026..27029
                     /locus_tag="LP245_001287"
     CDS             25026..27029
                     /locus_tag="LP245_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBL1519217.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27048..27518
                     /locus_tag="LP245_001288"
     CDS             27048..27518
                     /locus_tag="LP245_001288"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBL1519218.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27539..28123
                     /locus_tag="LP245_001289"
     CDS             27539..28123
                     /locus_tag="LP245_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBL1519219.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28138..29124
                     /locus_tag="LP245_001290"
     CDS             28138..29124
                     /locus_tag="LP245_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBL1519220.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29114..29425
                     /locus_tag="LP245_001291"
     CDS             29114..29425
                     /locus_tag="LP245_001291"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBL1519221.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29447..31228
                     /locus_tag="LP245_001292"
     CDS             29447..31228
                     /locus_tag="LP245_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBL1519222.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31221..32597
                     /locus_tag="LP245_001293"
     CDS             31221..32597
                     /locus_tag="LP245_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBL1519223.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32604..33239
                     /locus_tag="LP245_001294"
     CDS             32604..33239
                     /locus_tag="LP245_001294"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBL1519224.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33269..34624
                     /locus_tag="LP245_001295"
     CDS             33269..34624
                     /locus_tag="LP245_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBL1519225.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
BASE COUNT        11490 a         5987 c         7455 g         9837 t
ORIGIN      
        1 ttaataaaaa aggaagaata ttcatgtaaa cgattttatt gtttttttct cttttataca
       61 aaaagggtca taatttcaag taagcggatg aattcatgag gattttttgc atactgtctc
      121 tactatactt aggtcactaa gaaaaaggag tgatttatta tgaaaaagaa catgattggg
      181 acattattac tttcaacact tcttctaggc ggcttggcaa caccagcttt tgctgagggt
      241 caagcgactt caaaaggaga tattaccttt actgaaccaa caaataccgt ggagcctctt
      301 aaccctactg atccttcaaa accagtagag ccagcagatc cggaaaatcc agcaactggc
      361 cagacaggtc ctttaacact ggatgtagtt cccgaattgc catttggtac acacgagatt
      421 gaaagcggaa caaaaacgta tcaagtagac gcttcaaaaa acgatacacc ttatctccaa
      481 gtatcagatc gtcgaggtgt aggtgcagat ggccaagcac aagggtggaa cgtgacagtt
      541 tcggtttcag attttgtaaa cggttcacaa gttttgcaag gcgctgaatt agattttgga
      601 acatccactg ttaaaagtac gtcagataac gaatccactg gaccaactag tcaaactgta
      661 actgggttga gtaaagcaag tgcagcgaca ccaatattta cagcagcaaa agatcaaggt
      721 ctgggaacat ggctttctgt ttatgatcca gcaaatatca cactgaaagt gccgaaagca
      781 gcagctggaa cattcacggc tgatttgact tggaacctcg tggctggccc agtagcatag
      841 agtatgaaat aaattcaaca aactgcggtg aaaatactat aggtgaagga ttttttaccg
      901 cagttgttgt tgaaaggatg tggtggacaa tgaatcaaag taaacgactg tttgtttcgt
      961 ttttttctat tttaagtcta tttttcattt ttccgtcaat cagccaagca aaggattcag
     1021 caggagactt tggaatcaaa ccggtatttc cagagaacca aatagataaa gcaatcggtt
     1081 attttgattt attagtggca ccggaacaaa atcagacact agaagtaatt atcagcaatt
     1141 cttcagatga agaacgaaca tttgaggtct ctgtcaatcc ggcggtaacg agtgatggtg
     1201 gaacgatcga ttatagtcaa aaaaacccaa cgttagatga gacattgccg tttgatgtcc
     1261 gtgacgtttt gctcattgcg aaaaaggaaa tcaatgtatc agcacatgca gaaacaactg
     1321 tacctataga agtgaaaatc ccagcaaaaa gctttaaggg acgtgtatta gcgggtattc
     1381 atgtttcacc taaagaagaa gctgaaacag aaaatgctac agaaggagca caaatcaaaa
     1441 atcgtattgc ttataatctc gcagtcgttt tacaagaaag tcaagagacg atagaaccgg
     1501 atctgaaact tttatcagga gatttggacg aggtcaacgc aaagccaact gttcagcttc
     1561 gtttccaaaa tcctcagcct aggattatca gcaatttgat atttacgagc aagatctttt
     1621 atgaaaatca gctttatatt gaaaatacgt ctaatgcatt tttagttgca ccaaattcga
     1681 attttcactt gaatcttgat ttagctggtg ataaagcaaa agccggcgat taccgcgcag
     1741 aaatcatagc aaaatcaggc gacagtaatg aatggcgatt tacacaaaac tttacgatca
     1801 aaaaagaaaa agcacaaaaa gtaaatgaaa attccgtttt tgcagtacaa gaacaatctt
     1861 tcccatggct ttatgcagga ttggttgctg cagttctagt gttatggttg attttgctgt
     1921 ttttgtgggt ccacaagaaa aagaaaaaag gagaaacaac atgatgaggt gatttcgttg
     1981 aaaacatcga tcttattggg agggattatt gcaagtttgc tgttcttcag ctggcaagag
     2041 ccagtccaag cagataccaa aagttcaggt acgattacat tttatgatct aagtccaatt
     2101 ccgcatccaa gtggttcagt caatggcgca tcaaaacagc agacacagct accgatttat
     2161 aaagaatcta atcaacatgg cgtattcccg gagacgaatg aacaaaagat ccgttttctt
     2221 tatttgatca ttggtataga attatggctt cttgcgtggt tgttgttatg gagaagaaag
     2281 gaaaaggagg atgaacatgt tgctacaaaa taaattttca ttttttcgct ccttcttttt
     2341 tacttcgctt tttgttttaa gtatatttat cttttcacct tcggcagaag ctgttggagc
     2401 aacgcctcct gccatttctt atgatccata cacgtatgaa aatatcgtac ctccaaatgg
     2461 tggacgtagt gcagtcaatg gcgggaagct tgtccaacta actggggcta accaattgcc
     2521 taaattgact gctacttatt tgaacgatgg ttcaaatgat ccttggaaag gtggcacggt
     2581 ccgttttcat tgggaaagcc atgtgaaact aacaaatgta cttgatttgg tgaatatcac
     2641 tgcacaagga tttgcatttg tggcgatcat caatttgccg gaacatgtat caagcagtga
     2701 tgtattaaaa gcaattgact ggaacaacgc ctacttgtat attgccggtg cccccatcaa
     2761 ggttactagc ggaagtttat tatcagcagg aagccatacc ttgcgttttg ggatggggtc
     2821 gtgggataca aatactctat tgacagatat tattgctatt attacgcgag gcgaattcaa
     2881 cgtggacgat atcccgcttc aatttgatgt tacagctaat gtcgcgaaga tgacagaaaa
     2941 cggagataaa tatgatacga gtccaaacaa aattttgacc aagggtaaat tacaaccttc
     3001 tatgtctaaa aaggccgttt tttctgttga tttttatgat tcgaataata ttatccaaga
     3061 tcgtatgttc aattcgattt tagctccagc tgcaggtaga ttttatccta aattaactgg
     3121 cggaaacttg aatccaggag catatgcatt ttctgcaagt gcagagataa atacgtggaa
     3181 tagttacatc tcaccaagtg attcaacagg aaaatataat acatttgctg ataccacaga
     3241 atacgtggat ggaaataacc agaaccttcc aggctctacc aatagtcgga cattgacgat
     3301 ggggctgact gaaggacgtt ttgatcagtt gccatttagt cgctttgatc gcgtagtcaa
     3361 ctattttaca ggaaaaaacg ttacacaagg agcaatactg actcatactc cagcaagcac
     3421 aagtggattg aatcagacag ccaatatcgt gtacagtggg aaagatgcgc aaggcggatt
     3481 gctttctcct gttgctttaa aggtattgga gcagtacaag ctagacggaa cggttttacc
     3541 aacaaactta acagccgata gtcagtgggg aaagctcctt tcttctgcat cgtaccaagt
     3601 cacggccaat tggtcagcaa ctgaactaaa aaagggttcg atccattaca ggctttattc
     3661 gaaaggaacc caaaaattag cgacaggatg gacagatcaa cttttccaaa cgatccaatc
     3721 aaataacggg ggtgtaaata cagctacttc tacactacct gcattggctt cagggcaata
     3781 ttattttgat tatcgcttgg tggacgatgt acttactaac atgtatccgt cttttgcgta
     3841 caaatggcag tctgaacaag ctggaatcac cactcttcct caaataacag tggctaattt
     3901 tccatctgtg agtgcagata gtcagctaaa aaaccttagc agacaacctg agacaggaga
     3961 tcccctgtct gctctatcag gagatacgat tcaagaaaat gtgacattca cgttaacaaa
     4021 atctggggat gcgataaccg acaaaaaaat cacgatctca cttcctgaaa atactactta
     4081 tatcaatggt tccttaaaat taaatggtac aactatcgca gataccggca ttcaacaagg
     4141 agtttctgtc ccagcagatc tattgagcaa aataggagat accattcatc ttacttacaa
     4201 ctatcaatta aatactgtag atacttcttt acaatccgtc agcatactga caaaggcagc
     4261 tgtactttcc agcaatatta cattagcaga tggtgctaag cttcctaacc cagttgtcca
     4321 aacatctgct aaaacaattc ttgtccccaa acaagaatta acattagtta atgtaccaga
     4381 tgattttaca tttggtaacg atctccccaa accgttgaag acaagttatt atgaatcaaa
     4441 aggcgatttt tcttttgatg tgcgggatac tcggcttcca agcacgtctc cttggcaact
     4501 gacaggtaca ttgacttctt tatttaagaa tgatcaaggt caagaattaa gcggaacaaa
     4561 attatacttc aatcattctg gatcaaagca attgattcag caaggtcaaa acacgttgat
     4621 ttatgagagt gatggaacag ctaaaggaga ggttctcgtt gactttcccg ataccgatgg
     4681 tttactctta gaggtaaata gcagtacgaa tgctcaacct ggcgcaacgt atcaaggcat
     4741 ggtcacatgg gaactgacag ctgggccaac cagctaagtg attagaattt gtatggatct
     4801 gtgataactg tcacagatcc tctttttcaa ggatgagaag gaaacttctg ctgttaaaat
     4861 cagaaatgct tgaaggagtg gacttggaac ttttcagttt gcttgaaaaa aatgaacaac
     4921 ggcaaatcaa acttttccaa cttttattag aggaaaaagg agaggtttcc gttaataacg
     4981 tacttacccg cttatcagtt gatcgggcta ccttgaaaga agatctgttt tatttacaag
     5041 ctaacttgga aaatatcaaa caattggaaa ttgttatcca agaagggaat attttattaa
     5101 tcagacatgg aaatatagca gcagtcgatg tttattatca ttgttacttg cgctattcta
     5161 caaaatatca gatacttctt tatctgttgg aaaatggctc atttgatcgg cagaaacttg
     5221 tcatggaact taatatcagt tcggctactt tgtctcgcag agtgaaggaa ttaaatgatt
     5281 ctttaaatga gtttcatctg aaaataaaaa gcgggcggct gaccggtcca gaaagtcaaa
     5341 ttcgttattt ttatttccaa ttattttggt ttggacgtcc ctatcttgaa aacaaaaaag
     5401 aatacagtga tttatcagga aacacttttt tagatctgct gcaaaaagag tttagttttg
     5461 ctattacaga agaaggacga ttgaaatttg aaatatggct ttccattatg aagaagcgaa
     5521 tgcgctgtac gaaaaaatcc aaaccagatt atagcaatct tcctgttgga ttgtttcaaa
     5581 cgacacaatt tttattggac ctccatacat ttttgacccg ttacttcttt caatatgcct
     5641 ttccttggaa tcaaaatgaa acgttggttt tttatctttt catgatcagt aactttacat
     5701 tagatacaca taactcgcat gtccaggagt ttttgataag cgaaaaatac aaagacgacg
     5761 tagtagctca attgaatcga acgtttaaac aatcgataga agaatatttc tctttttatg
     5821 tttttccaga agagatttcg caaaagattg cgttgacagt gatgcaaaat cacgctcatt
     5881 ttgcctattt tagaggatgg atgaatattt ttggccaaga aggattaaaa cagcggttaa
     5941 ctgaagtaga agataaacaa ttcctggttt tatgtgaaag attggtcaga caaacatttg
     6001 ctattgttga ttttactgaa gtagacgagg aaaatgcccg ctttgaatta tttgctcgct
     6061 atgcatctat tttacggacg ctgatcaagc agttagaatt acgtctgcaa attgcttatg
     6121 atcttcctta tgaaaggcta atggcggata tcgtgaaaga aatcatccag gaacaattgc
     6181 tgaatacgat caaatatgat ttagtcgaat acgagaaaga aaagcagtat gatatcattt
     6241 tgactagcca attgaaagag tacccgtcac agaagtccgc taaagttttt gtattcacta
     6301 gcaacgaata taattatgat ttcccctatt tgaaccaatt tttaaaagaa tgttatttag
     6361 aaaaattgaa tttaaggatg aataaaacat gaaaatcgtg atcattggtg cttcccatga
     6421 aggcatcaca gctgccctaa atctaagaaa acttcaaccg aaagcagaag ttttactgat
     6481 cgatgaagat cataaagatg gactaggcta tgtttcaaat ggaatcaacc tttatttaaa
     6541 aggaaagata cgtagtttag ctgaagttgc ccataacatg cggactcttc aagaaagtgg
     6601 ggcaaaactg atcaccgaat ggagagtaac tgaacttgat ccagacaaac atcagctcat
     6661 cctcgcatcc aaagaaggaa aaaacgagac cataacctat gataaattaa tcgtagcgac
     6721 aggttcctct cctgtcacct tgtataaaca aattgaagct gaaaatgtct acacctataa
     6781 aaatctagtg caatctaagc aagtacttgc cgctttaaaa gaagcaaaag aagtagtgat
     6841 cttcggtgct ggttacattg gattggaatt agcagatgct ttgagaaata aaggatacat
     6901 tattcatcta gttgattata tgccgaatgt tttatcaaga tatttcgata aggatatgat
     6961 caacagtttt caaaatcagc tgcaaactaa gcaaataaat ttttatccaa atgaattctt
     7021 gatcgattgg aaaaaatcag aagagaaagt agtatccgta caacttctgt ctcaaacaat
     7081 aaaggcagat atggtcattt tttctgccca aactcgtcct aatacgacat tgttaaaaga
     7141 aaaagtggct ttgtatgagg atgagactgt gatagtcaat gaatatctgc agacaagtga
     7201 tccggacatc tatgcgattg gagatatcgt cccagtcagt tttgacaaaa ataaacggca
     7261 tctcttttta cctttagtta ctcgagctgt acatatggca agagcagtag cgctaacttt
     7321 gagtggtcag ccaaccgctt acgacctcag acaaaagata acagcagcag tcattataga
     7381 ctacttttta ggaactgtag ggctgacaga agatgaagcg ccattcttgg aacaaaatac
     7441 cggttcgtgt tcaggagaat ttgatctatt tccacaatac gacgaagaaa acaaaacagt
     7501 aaatgcaaag ctgatctacc atccggatac attagaaata attggcggac agctgataag
     7561 ccaagaattc ttattatcag atttgaacct gcttgcggat atcgtgaaac acaaaactac
     7621 gattccacag ctagcagttg aggattttgg atttctgtct gaatacacct ctcgttttca
     7681 ctacctcaat gagttagctt ttaaagtact agctaagaga gcaaatagca atagagtaga
     7741 taaaagactg tgagaaatat cacggtcttt tattgtgtgg ggatataata aatattaatc
     7801 aatcgagaat aaaaaattca tataatgaaa tagcggaaga attttttgag cataatattc
     7861 gccaaaaatt tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt
     7921 taaatgtttt tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca
     7981 ggggtgatgt ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta
     8041 gctcaagata atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa
     8101 gatgcaaatt caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa
     8161 ggtgggaaag tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca
     8221 gaagaaggaa aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc
     8281 aatcttgttg aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg
     8341 aaagaagaat atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg
     8401 tttaaactaa ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca
     8461 accatcaatg cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg
     8521 attaacgcaa tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc
     8581 aaaatttcta aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga
     8641 tttatgatcg gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta
     8701 ctgacgatgc aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga
     8761 tttattgcgc gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt
     8821 ggtctattag gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc
     8881 aattggctgt tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca
     8941 ctattttctg ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga
     9001 ggaagaacat gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc
     9061 aagtagttaa agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa
     9121 tcatcggtcc ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga
     9181 cgcctagcag tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg
     9241 aacgcgttaa actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc
     9301 cttttctgac agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc
     9361 aaaaagaagc aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc
     9421 cagaagaact atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg
     9481 atccgtccat tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag
     9541 aagtagtcga tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta
     9601 ctcacgatac acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat
     9661 tgaaagaaaa agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat
     9721 acacagcaaa aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc
     9781 acttcaacaa gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat
     9841 ttcggtgata aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga
     9901 aaagctttga gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa
     9961 atggcgcagt ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt
    10021 gaaagcaatc tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat
    10081 cgtgaacctt ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca
    10141 aaagaaatcg cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa
    10201 agacctgtgg aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta
    10261 ttaggagaag cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat
    10321 gacgaagatc gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt
    10381 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    10441 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    10501 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    10561 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact
    10621 taagctgatt ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa
    10681 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    10741 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    10801 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    10861 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    10921 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    10981 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    11041 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    11101 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    11161 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    11221 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    11281 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    11341 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    11401 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    11461 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    11521 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    11581 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    11641 cttattatcg cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg
    11701 ttcaactctg agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    11761 gtgacttgtg accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca
    11821 acgttttgtt ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    11881 tgttgagcta ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt
    11941 gacatgactt ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt
    12001 ggcaaaatga agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt
    12061 tgccgctact tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc
    12121 tgatgctttg tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac
    12181 agctaaatga tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt
    12241 ttctaaacgc gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc
    12301 ttctggtttt tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc
    12361 gactttcatc cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa
    12421 gacaagcagt ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct
    12481 atcttttaac tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg
    12541 tttcacataa gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc
    12601 actacctaaa acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg
    12661 cttggcttgt ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc
    12721 ttgaaacatc acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc
    12781 aaagctagta taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg
    12841 actaagttgg tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt
    12901 atacataaaa ctataccgca actcacgact tttcgttttc taagagattg cgagacatag
    12961 cattttttta aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg
    13021 tgaaagaacc aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt
    13081 cgtatggcgc acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt
    13141 atcggacggg aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta
    13201 gcagaattga aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct
    13261 gtcaatgcgc tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa
    13321 acagcagaat taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc
    13381 attgaagcaa tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat
    13441 accattaaaa atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt
    13501 aaacaaaaat cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag
    13561 aagagaaagg aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt
    13621 ttttctggag cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg
    13681 tcatttattg ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt
    13741 ccatacccag ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt
    13801 cacctagatg aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg
    13861 ctgcttaccc gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga
    13921 caggtagact ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt
    13981 ttgattttgc agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag
    14041 catagtttcg ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag
    14101 ctttgggtaa cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg
    14161 tacagagtag tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat
    14221 agtgaaagat aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa
    14281 gtcaaacaga tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa
    14341 ttggtaccag tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga
    14401 ttgaaagtgc aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc
    14461 catatgaaac ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc
    14521 agagtattgt ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa
    14581 atcgaatttg cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc
    14641 cgccgtttaa aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag
    14701 ttaaagagca taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat
    14761 gggatcgtcc gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat
    14821 gaccgctacg ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac
    14881 gatcaaagtg cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat
    14941 aatcgtttgc gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa
    15001 ctttctgctg aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt
    15061 aaaatggatc tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg
    15121 ggaatcagtg aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag
    15181 gaaaaagtag tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca
    15241 ggacctaaca caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg
    15301 gggcaagcag gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa
    15361 gtatttgcgg atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct
    15421 catatgacga acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt
    15481 gacgagctcg gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta
    15541 gatgatcttg gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa
    15601 gtttatggat ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca
    15661 ttaagtccaa cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc
    15721 tctagccgat taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat
    15781 gagagccaag atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag
    15841 accgaatatc tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg
    15901 aaagaagctt acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa
    15961 aaagcaaatg aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt
    16021 cgtaaaatgc aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca
    16081 aagacccaat tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag
    16141 aaggcgaaag aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc
    16201 caaagaggga cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta
    16261 aaaatgaatg tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa
    16321 cgagttatcc atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt
    16381 cgaggaaaac gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt
    16441 ctagctggtt atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag
    16501 ggaattactg attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca
    16561 aaccaaggcg gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc
    16621 agatggttcg ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg
    16681 tctttgatat gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac
    16741 ttgtattgat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt
    16801 tggatcagtt ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg
    16861 atgaaaatcc agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga
    16921 aaaaagatgg tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc
    16981 aaatgatcga tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa
    17041 tccagttccg tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt
    17101 gagtataatt acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta
    17161 attgaatatg aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt
    17221 cctgatcagc ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc
    17281 aaagccaaaa tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa
    17341 acggaacggc ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc
    17401 gaagcattgc tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg
    17461 ttaaaggatg ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg
    17521 gtgattactc gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc
    17581 ggtgcggcga atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa
    17641 cctagtcaga cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat
    17701 tatttcgacg tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta
    17761 aacggaggac acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa
    17821 aacatggagt ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc
    17881 atgactcgcc aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg
    17941 attgataaag gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa
    18001 cgagatgttt caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc
    18061 ggtcagtttt atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg
    18121 atcgacaagc ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga
    18181 gaaaagaaaa aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg
    18241 tttgatctga ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac
    18301 gcgatgaata tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg
    18361 acgaatcctg tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat
    18421 cggaaatata aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc
    18481 atctatcgca gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg
    18541 atcgatggag gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga
    18601 atcgatattc ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta
    18661 ttcggtacag atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc
    18721 cagcgaatcc aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt
    18781 aaaaacagtt ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa
    18841 atgctgctta aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta
    18901 caagaaatcg gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa
    18961 tgaggaaagg gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa
    19021 gagcgtttac gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat
    19081 gtgatttctt gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt
    19141 gggaactaca cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg
    19201 ctaattggcc aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg
    19261 acacaagacc aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat
    19321 gtcatcggtt atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa
    19381 ctgctttatt ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac
    19441 ttttggatgg aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct
    19501 aaaggaaatc agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc
    19561 attttggatg agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga
    19621 atattggaat tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat
    19681 gtagaaaaaa tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga
    19741 aaagtacatg agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta
    19801 agccaacagg aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat
    19861 acgttagaga ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact
    19921 cagttcggct acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa
    19981 ttgaaagcag gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa
    20041 aaatgttaag tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat
    20101 catttatgta gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt
    20161 ggctgataat gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt
    20221 caaagcagtt gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc
    20281 gtatttagta gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc
    20341 attaggacaa agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct
    20401 tcgagcgagt caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag
    20461 tttgactcga caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa
    20521 ctcgacagtc caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt
    20581 gacgtatgcg cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga
    20641 agtgatcctg tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt
    20701 acttgttgca ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca
    20761 attcaaagat atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat
    20821 tggaccattc ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt
    20881 tttagcagct ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt
    20941 gccagtgact tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga
    21001 tccaaacaat atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat
    21061 gccgattcgc ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt
    21121 acttgtagcc gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt
    21181 actcgtttat agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag
    21241 gaatgaacga aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt
    21301 gttcccagct tctttttgta tagacctatt ttatttattt tactatattg gatatatatt
    21361 cattgaaaat agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt
    21421 taatggaccg ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca
    21481 cggaaatcat caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga
    21541 gtgatataca tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc
    21601 ttaaagaaaa gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat
    21661 tcactatttt tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag
    21721 ataaatcgca gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata
    21781 cccggtcaaa agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct
    21841 tgtatatcga tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac
    21901 ttgttttgat gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat
    21961 ctgtcatcga tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca
    22021 aagtgatgga tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata
    22081 ttttgtggat tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg
    22141 cagcacgcta taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat
    22201 tgttttcttt tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta
    22261 aaaatctatc cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc
    22321 ttcaattcaa atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc
    22381 gtaaattgct ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct
    22441 atgagttgaa aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg
    22501 aagaggaaca aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc
    22561 aaaaacatat gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg
    22621 tgctgtttca tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag
    22681 accaatctta tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg
    22741 caaaagatct gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg
    22801 ggccattttc gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca
    22861 cagagcctca tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt
    22921 ggttcagtga aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta
    22981 atgggcacac gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag
    23041 tatttgtcat tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt
    23101 attcactatt atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta
    23161 ttgaacaaca atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc
    23221 aactaccacg caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta
    23281 cccagctcaa aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat
    23341 tgttccatag actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac
    23401 ggtgttcttc tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg
    23461 ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat
    23521 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa
    23581 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc
    23641 agaaagtcta ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta
    23701 cacggtgggt aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc
    23761 tttgaaccgc ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa
    23821 gatctttgac tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc
    23881 ttaacaaact gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct
    23941 gttgttcatg ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt
    24001 ccaaaacgac attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt
    24061 tcaatgcttc caagatcagt gcctgttcaa attggtctcg ttgaatattt gtttccgtta
    24121 gctttggatg aggatcttcc atgtaaagtt gtggactgac atcttgacca cctgcaagaa
    24181 taagtttgtc gatttgtcca atcagttgag gagctgaatc tggagacatg actggcagaa
    24241 taagaggcaa tccttgagca tctaaaactg catccacgaa tccttgcggt gtatagctca
    24301 cttgatttcc ttggaaagta tctgttgctc gaatcagttg atttccggca atgccgatga
    24361 ttggtttcat ttgtattccc cctaaagtag acttattgta acaaggattt aaaaaaaatt
    24421 aaactatgta agacttgccc ctatacttat ctgttcttgc tgtgttacta tctgtaaaga
    24481 gaaatttcgt gtgaaattca tgacgatagt tgaaaatatt gcttaatttg ttataataaa
    24541 aagtaagcag aaataaaaag gttgggcgta agcttcaagg atctagttct tcaaggggtg
    24601 agaaggacat tttattgaag gggcctgcct atactaagtt atctttagag gtacatactt
    24661 tcaatgaaaa aagaaagcat gtacctcttt tttaaatcga aaggaagtga agcaagtgtt
    24721 agaagctttg gaacaaatcc gaaaagcaga agaagaaaat gaaaagcgtg ctcaaacact
    24781 gcggcagcag ctgaagatct atgcaacaga aaaagagcag gaattggaaa cgatccaaac
    24841 aaactatcga caacaactaa aacagttggt ggaagaaaaa gaacaatttg aaatacaaga
    24901 attagaaaaa gaaaaaatga aattgaaagc agaagcagac aaggtgcaag caactttgaa
    24961 agatcaatat caaaagcatc agagtcaagc gatcggtgcg atcattgaaa gggtgaaaga
    25021 aacttatggc cgtcactaag atggaaaaag tgaccctcat ttcagataaa agaaatcagg
    25081 agaggatttt acaagcagta caaggaatcc aaaacgttga aatccgggat ctgtatcaaa
    25141 atagaacaaa caaccagtgg gtggagaagt attttccaga taccacgatt attgataaag
    25201 aagcaaaatt aagcgcttta ggtaatcggt tgaaagacat ccaagaagct atccaattca
    25261 tacaacacca cggcgatagc cgtcaaaaga aactccattt gaaacgtcaa gaactttcct
    25321 tacaagattt ggaagccaat tattccgaag aaaatttcat aaataaattg aaagaagtcc
    25381 ttgatttaaa agaaaagtgg gaacaactaa ctgaagaacg tgatcgttta gaagaagagg
    25441 aagaatggct tcttcattgg caacagctgg atattgctcc aagtatgtat gcaagtaaga
    25501 cgaccatttt tgagatgggg actgtgagtg cagcaaattt tgaaagtttc aaggaagaac
    25561 tgagtaagct tgatgacgtt tatatggaag aaatagatta tacgccaaaa caagtttatc
    25621 tttcgtatgt tgctttaaaa aaatcagttg ctgttataga agaaattgct gggaaatacg
    25681 ggttcaataa agaaacgtat ccttatgaac aaaatcctaa agaaaaactg caagagacca
    25741 agcagcaatt atccattgtt cacgagcagc aaaagaagat aacgacagcg ttaggtcagt
    25801 gcagtggcta tatccaagaa tttgaatggg tagaagaagt cacacttgcc gttgcagaac
    25861 gagaaaaaat aaaagaacgg tttatccatg cgacttatct gatcgttttg caaggttggg
    25921 tagatgcaga agaaaaacag aatttgctgc atgtgttaaa cgaaaccgta tcagaagaag
    25981 atatatacgt cagtttcgaa acaccaaact cagaagagat tcagcaggaa gtccctacta
    26041 aattgaaaaa ccatccgctt gtcgaacctt ttgaattgct gactgaaatg tacagtctgc
    26101 caaaatatga agaagtagat ccaacacctt ggatgacacc attttatctt gtcttcttcg
    26161 ggatgatggt cgcagatgtt ggttatggtt tgctgatgct cattgggaca atactagctc
    26221 aaaaactact tgttctacca cgcgggatga aacgtttcgt aaaattcttt gagattctct
    26281 cgataccatc gatcatctgg ggattgatct acagttcatt tttcggacag tcattaccaa
    26341 aagaactgtt tggcatccgc ttgcctttcc caatcctatc tacgacggat gacgtcaata
    26401 cgattttgat tttatccgtg attttcggtc tgatacagat tttggttgga ttatttgtgg
    26461 cagcaaagga aaatatcagg agaaaagatt acttgagtgc tgtcagtgat ggatttgcct
    26521 ggcaagggat cctaattggg atcgttattg cgttggttgg tgccatgttg ataaaaaata
    26581 cagcatttgt ttaccttggc gctgggctat cgatcattgc tgccttatgt atcttgatcg
    26641 ttccgattat ccaaacgccg tctaaagtca aaggtgctgc caaaggtgcg tataatcttt
    26701 acggactgac cggctatatc ggtgatttag tcagttatac acgtttgatg gcattgggta
    26761 tttcaggcgg aagtattgga gcggcattca atatgctagt tgctttcatg ccgccagctg
    26821 ctcgattcag tgtagggatc cttttgatca tcgctttaca cgcactgaat atgtttttga
    26881 cactgctaag tgcctatgtc catggcgcac gattgcagta tgtcgaattt tttgggaagt
    26941 tttatacagg aggcggacgt gcctttgatc cgctgaaaac ggcggaaaaa tacgtcaaca
    27001 tcaatcacaa gaaaaaaaac aataaataat tggaggattt ttatataatg atggattact
    27061 taattagtca aaatggtgga atggtatttg cggtattagc gatggcaaca gcgacgattt
    27121 tttcagggat cggttcagct aaaggtgttg gaatgacagg tgaggcagca gcagcattga
    27181 caacaagtca acccgaaaaa ttcgggcagg ctctgattct gcaattgctt ccaggcacgc
    27241 aaggtttgta tggattcgtt attgcctttt tgatttttat caacttagga aatgacatgt
    27301 cagttgtaca aggactgaac tttctaggtg cttctctgcc gattgctttt acaggcttgt
    27361 tttcaggtat tgcccaagga aaagtcgcag cggcaggtat tcaaatttta gcgaaaaaac
    27421 ctgaacatgc tacaaaagga atcatttttg ctgcgatggt tgaaacatac gcgattttag
    27481 gtttcgttat ttccttccta ttagtgttga atgcctaagc ataaaggagg aaaagcagat
    27541 gaacgccatt gaaaaaatca tctctcagat gaacgaagca gcagagcagg aaagagcggc
    27601 gttagaacaa gaagagcgaa tgaagatcga tcaaaacttt gaacaaaaac gtacgcaagt
    27661 tgaaacagaa catcaaaaac aaaaagaaaa acaaatcgaa ttactcgaaa aaaaataccg
    27721 tcagctaagg aatcgccagc aagtagaagt acgacaagaa aatttgaatg cgaagcagga
    27781 atttttaaga cgattgtttg cagatgcggt aactgaaatg gaaaattggg atgaatctga
    27841 acaaatccag tttatcaaaa atgcattgta ttcattacct ttgacaggaa aagtagcatt
    27901 cattgctgga gaaaaatcag cagcctatct ttctcagacg ttgttggatg aatggaacaa
    27961 tgaacttccc tttatgatgg ttttaagtga tgaaactgtt gctgatcaag cgggttttct
    28021 gataaacgat caaggagttc agtataattt tcttttcagc agccttgtac aagatatcca
    28081 aggaacgatg agttttgaga ttgccaatca attattcgaa taaggaggga tcagtgtatg
    28141 gaataccacg aactaaatcc cttgattcgc ggaagagagc ttgaactttt gtccaatgag
    28201 acatttgaac ggatgattca aacaaattct gtcgaagcac ttggtgaaat attgaaatcc
    28261 acgatttaca gtccatatat ttatgacgga tatgaatatg acttcgaaca gaatctttta
    28321 aaggagcaga gccgtctatt tcgctggtta aaggaatcag caccggagcc tgaaatcgtt
    28381 tggatctata cgatgcgtta tactttccat aatctgaagg ttttgacaaa agctgagatg
    28441 acaaatcaaa atctggacca tttgtatatc gacgatggat tttattcatt agaaaccttg
    28501 aaggatgcca ttcatacgca agtttcaaat gaacttcctg aaagcattat ggacagtata
    28561 cgagaagtac gtgattattt tgaagagtct accattcttc agggaattga cgtgatttat
    28621 gatcgacagt ttttgacaga gcagcgacgg cttgccgata agctaggata tcaagaattg
    28681 ctgacagaag tcattgcttt tattgacttg accaatatca caacgatggc tcgaggaata
    28741 ttgcagaaaa gaacatatgg gttcatgacg acggtacttt ccagctcggg aagtatcgaa
    28801 aaagaagtat ttttgaactt tgtagataaa gatatggaag attacacgaa ttttctatta
    28861 gagacagatt atgctgattt tctgcgccct gtcatccgtg agggaaatat tgatctcgta
    28921 aagcttgaac agttgaaaga tgattatcta agttcattgt atcaagaagc acaaacccag
    28981 gctttcggac cactgccact actagccttt ttgaacgcaa aagaggtaga aagcaaaaac
    29041 cttcgtttac tggttatcgg caaaagaagc catttcgaat cagaaacaat cagaaagcgg
    29101 gtgagacaag tctatgacgc ataagatcgg tgtagttggc gacaaagatt ctgttttgcc
    29161 attcaaattg tttggctttg atgttcgtta tggtacaacc aagcaaaccg ttcgtcaggc
    29221 aattgaagaa atggcaaaga atgagtatgg cgtgatttat gtcacagagc aatgtgcagc
    29281 attgagccca gaaacgatcg aacgttacaa ggaacaaatg atacctgcta tcgtattgat
    29341 tcccaatcat caaggatcat tagggatagg gctggaagaa attcaaaaaa acgtagaaaa
    29401 agcagtaggt caaaatatct tatagtatga aaaggagata gaaattttgc aaattggaaa
    29461 aatcataaaa gtctccggac ctcttgtaat ggctgagaac atgtctgatg ccagtatcca
    29521 agacatgtgt ctagtgggag atctaggagt tatcggagaa attatcgaga tgcgtggcga
    29581 tgtggcgtct attcaagtat atgaagagac ttctggaatt ggtccaggcg aaccggttcg
    29641 ctctactggt gaagctttat ctgttgaatt aggaccaggg atcatttcac aaatgtttga
    29701 cggaatccaa cggccattag atacctttat ggaaatcaca caaagtaatt tcttagggcg
    29761 cggagttcaa ttgcccgcat tggaccatga gaaaaaatgg tggttcgaac caacagtaga
    29821 agccggagaa acggtgagtg ctggagatgt tatcgggatc gtagaagaaa caaaagttat
    29881 aaaacataaa atcatggtgc caaatgggat aaaaggaacg atcaaaacaa tcgaaaaagg
    29941 ttcattcact attgatgaaa cagtatgtgt cattgaaacc gaaaatggtg acaaaaattt
    30001 gacgatgctt caaaaatggc cagtaagacg tagtcggcca atcaaagaaa aattaaaccc
    30061 ggatgcaccc atgatcactg gacagcgagt gattgataca ttcttcccag tgacaaaagg
    30121 aggagcagca gctgtacctg gtccttttgg tgcagggaaa acagtcgttc agcatcaaat
    30181 tgcaaaatgg gccgatgtgg acatggttgt ctatgtggga tgtggcgagc gtggaaatga
    30241 gatgacggat gttttaaatg aattccctga attgattgac cctaatacag gagaatcgtt
    30301 gatggaacgt acggtattga ttgctaatac atcaaacatg ccagtagcag ctcgagaagc
    30361 ttctatctat acgggaatca caattgcgga atatttccgt gacatgggtt atgacgttgc
    30421 tatcatggca gactccactt cacgatgggc agaagcactt cgtgagatga gcggacgttt
    30481 ggaagaaatg cctggtgatg aaggttatcc agcttatctt ggttcacggc ttgcggaata
    30541 ctatgaacga tctggaagag tcattgcatt aggatcagaa ggtcgcgaag gaagtataac
    30601 cgcaatcagt gctgtatccc cgtctggagg ggatatttcg gaaccagtca cacaaaatac
    30661 attgcgggtc gtaaaagtat tctggggtct tgattccagt ttagcccaaa aaagacattt
    30721 tccttcgatc gattggatac aaagctattc tctttattca acagaagtag ggaagtatat
    30781 ggatcatatc cttcaagctg actgggcatc catggtcacc gagggcatgc gtattttgca
    30841 ggaagaacag cagctgaatg aaatcgtgcg tttggtaggg attgattccc tttcagataa
    30901 tgaccgtctg acattagaag tggcaaaatc cattcgtgaa gattatttgc agcaaaatgc
    30961 ttttgatgat gtcgatacat tcacttcaag agagaaacaa ttcaaaatgt tgaagatgat
    31021 cttgaccttt ggtgaagaag gacgccgtgc gttgtcgtta ggtgcttatt taagtgagat
    31081 catggacggt accgtatcga ttcgtgaaag gatcggacga agcaaatata tcccggaaac
    31141 agaattagaa aaactagatc aaattattgg tgaaatcaag caaacgatgc aaacgatcgt
    31201 ttcagaagga ggcatgagca atgattaaag aatatcgtac gatcggtgaa gtcgtcggtc
    31261 cattgatggc ggttgaaaaa gttgctggtg tcaaatatga agaattaatc gaagtccgta
    31321 tgcaaaatgg cgagattcgt cgtggacaag tattggaagt ccaagaagat aaagcaatgg
    31381 tccaaatatt cgaaggaaca agtggtatca atttacgtga ctcttctgta cgatttttag
    31441 gccatccttt agaactaggt gtatcggaag acatgatcgg tcgagtattc gatggtttgg
    31501 gacgaccgaa agataacgga ccagagatcc tgcctgaaaa gcatttggat attaacggag
    31561 aagtaatcaa tccagtagct cgggattatc cagatgagtt tatccaaaca ggtatctctg
    31621 caatcgatca tttgaataca ttagttcgtg ggcaaaaatt accagtattt tctggctctg
    31681 gtcttcctca taaagaatta gctgctcaga tcgcgcgaca agcaacggta ctcgattcat
    31741 cagatgattt cgccgtagtc tttgctgcta ttggaatcac ttttgaagaa gctgaatttt
    31801 tcatggaaga ttttcgtcaa acgggcgcaa tcgaccgttc tgtcatgttt atgaatttag
    31861 caaacgaccc tgcaatcgaa cgtatcgcta ctcctcgtat ggctttgact gctgcagaat
    31921 atcttgctta tgaaaaggga atgcatgttt tggttatcat gacagacatg accaactatg
    31981 cagaggcatt gcgagagatt tctgcagcac ggcgagaagt tccaggaaga agaggatatc
    32041 ctgggtatct ttacacgaac ttagctactt tattcgaacg agcaggaaga atccgcggac
    32101 taaaaggatc ggttactcaa attccgattc taacaatgcc agaagacgat aaaactcatc
    32161 caatccctga cttgactggt tatattacag aaggacagat catcttgact agagagcttt
    32221 acaagagtgg gattcagcca ccaattgatg tactcccgtc tctttcgcgg ttaaaagata
    32281 agggaactgg acccggaaag acaagagaag accatgcagc tacgatgaat cagctttttg
    32341 cagcctatgc acaaggaaaa caggcaaaag aattagccgt agttttaggt gaatctgctt
    32401 tatctgatgt agacaagatc tatgcgaagt ttgctgagcg gtttgaaaaa gaatatgtca
    32461 atcaaggatt ctacacgaac cgttcgatta ctgaaacact tgatctaggg tgggaactgc
    32521 tatcgatgtt gccaagaacc gaattaaaac gaatcaaaga cgacatgctg gacaaatatc
    32581 tgccagaagg gaagtgagtt ctgatggcac gattgaatgt gaatccgacc cgcatggaat
    32641 tgactcgatt gaaaaaacag ttgacaactg ccacaagagg gcataaatta ttaaaagata
    32701 agcaagatga actgatgcgt caattcatcc tgttgattcg aaagaacaac cagctgcgtc
    32761 aagaaatgga agagtctatg acagaagcaa tgtctgattt tgtattggca aatgcttcga
    32821 tcacggaacc tttcatcgaa gaattatttg ttttgccggc ggaaaacgtt gatttgtcta
    32881 tcgtagacaa aaatatcatg agtgtaaaag tacctgtgat gaattttgaa tatgatgaac
    32941 agctgacaga cacacctttg gaatacgggt atttgaattc cagtgccgaa ctggatcggt
    33001 caatcgatcg gtttactacc ctgcttccaa aacttttgga actgacagaa atcgaaaaaa
    33061 cttgtcaact gatggcgagt gaaatcgaaa agacacgtcg gcgagtcaat gcattagaat
    33121 atatgacgat ccctcaatta gaagaaacga tctattatat tcgtatgaag ctggaagaaa
    33181 acgagcgcgc agaagtaaca aggttgatca aagtaaaaaa tatgggtacc actgactaag
    33241 tggtatcttt ttttaaaaga ggaaaacgat gattaaacaa agcaaacaaa taaagaaacg
    33301 tttgccggct gttcagcttc tcgcattagg attttttctc ctgattttag ttggcggcgg
    33361 cctacttacc ctaccatttt ttagtaatag tgggcatggg acaaatttta tcgatgcgct
    33421 tttcactgca acttctgctg tctgtgtaac gggattgaca acattgaata cagcagagca
    33481 ttggaacagt gctggtcaat ttttgatcat gcttttgatt gagatcggcg gtcttggttt
    33541 tatgatggtt ccgattctat gctttgcatt gataaagaag aaagtcagtc tcagcacacg
    33601 tattatatta aaagaagcgc tgaatctaga agaagtatca ggtgtgatga agctcatgct
    33661 ttacatccta aaattggcct ttgtgatcca attgattggt acggttgctt tatcttttgt
    33721 atttgtgcct gaatttggct ggttgaaagg tatctggtac agtttgttcc atgcaatctc
    33781 tagtttttgt aatgcagggt ttgatttgtt aggagacagt ttagccaatc accagcaaaa
    33841 tgtttatttg atcatggtgg tatctgcttt gatcatttct ggtgggttag gcttcatcgt
    33901 atggcgtgat ttactggaat atcatcagaa aaagaagatg acgattcatt caaaaatcgc
    33961 attaaccgtt acaggtaccc ttttattagg cggattcgtt gtgttctttt tcacagagcg
    34021 caatggggca acgctagtgg aagggaatat gtttcaacga ttggcaaaca ccttttttat
    34081 gagtgtgaca cctagaacgg ctggatatta ttcagttgat tacctccata tgagccatgc
    34141 aggtctgatt ttaacgatgt ttttgatgta catcggcgga acatctgggt cgacggccgg
    34201 cggattgaaa acaactacgt taggtgtgtt gctgatccag atgcgttcga tgttgaaagg
    34261 acgtacgaga gcggaagcat ttggccgtac catccgacaa ggcgcagtgt tgcgggcact
    34321 tactttattt tttgttacgt tgacgttgtg tgtagtcgcc atcatgattt tatcggtgac
    34381 tgaaacgata cctaaaactt ctggcatcga atatattgct tttgaggtct tctctgcgtt
    34441 tggtacagta ggtcttacga tgggattgac gccagacttg actgcaatag ggaaattgat
    34501 cattatagcg cttatgtaca ttggacgagt tggtgtattg actgtggtct tctctctgat
    34561 gacaaaagca caaagaacac aatcaaaata caaatatcca gaagaaagtg tcatgattgg
    34621 ataatttcat cttctgacag aaacctagtg atttagtaaa ataagaaaat aaaataattt
    34681 ttcttgcttc ttggatactt taagtgcaaa atgttcgttt attttttgag gcactacccg
    34741 ttgttgaacc tcgggtagtg cctcttttt
//
LOCUS       DAFEEZ010000025        34679 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000025
VERSION     DAFEEZ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.025"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            634..1323
                     /locus_tag="LP245_001296"
     CDS             634..1323
                     /locus_tag="LP245_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1519226.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1310..2518
                     /locus_tag="LP245_001297"
     CDS             1310..2518
                     /locus_tag="LP245_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1519227.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2812..4083
                     /gene="serS"
                     /locus_tag="LP245_001298"
     CDS             2812..4083
                     /gene="serS"
                     /locus_tag="LP245_001298"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBL1519228.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4632..6116)
                     /gene="guaB"
                     /locus_tag="LP245_001299"
     CDS             complement(4632..6116)
                     /gene="guaB"
                     /locus_tag="LP245_001299"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBL1519229.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6621..7316)
                     /locus_tag="LP245_001300"
     CDS             complement(6621..7316)
                     /locus_tag="LP245_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBL1519230.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7406..8506)
                     /gene="ychF"
                     /locus_tag="LP245_001301"
     CDS             complement(7406..8506)
                     /gene="ychF"
                     /locus_tag="LP245_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBL1519231.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8515..8706)
                     /locus_tag="LP245_001302"
     CDS             complement(8515..8706)
                     /locus_tag="LP245_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBL1519232.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8727..9617)
                     /locus_tag="LP245_001303"
     CDS             complement(8727..9617)
                     /locus_tag="LP245_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBL1519233.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9604..10371)
                     /locus_tag="LP245_001304"
     CDS             complement(9604..10371)
                     /locus_tag="LP245_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL1519234.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10383..11096)
                     /gene="rsmG"
                     /locus_tag="LP245_001305"
     CDS             complement(10383..11096)
                     /gene="rsmG"
                     /locus_tag="LP245_001305"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBL1519235.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11328..13229)
                     /gene="mnmG"
                     /locus_tag="LP245_001306"
     CDS             complement(11328..13229)
                     /gene="mnmG"
                     /locus_tag="LP245_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBL1519236.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13246..14643)
                     /gene="mnmE"
                     /locus_tag="LP245_001307"
     CDS             complement(13246..14643)
                     /gene="mnmE"
                     /locus_tag="LP245_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBL1519237.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14942..15325
                     /locus_tag="LP245_001308"
     CDS             14942..15325
                     /locus_tag="LP245_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519238.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15493..16251)
                     /locus_tag="LP245_001309"
     CDS             complement(15493..16251)
                     /locus_tag="LP245_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBL1519239.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16269..17087)
                     /locus_tag="LP245_001310"
     CDS             complement(16269..17087)
                     /locus_tag="LP245_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBL1519240.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17084..17440)
                     /gene="rnpA"
                     /locus_tag="LP245_001311"
     CDS             complement(17084..17440)
                     /gene="rnpA"
                     /locus_tag="LP245_001311"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBL1519241.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17558..17692)
                     /gene="rpmH"
                     /locus_tag="LP245_001312"
     CDS             complement(17558..17692)
                     /gene="rpmH"
                     /locus_tag="LP245_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBL1519242.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18215..19549
                     /gene="dnaA"
                     /locus_tag="LP245_001313"
     CDS             18215..19549
                     /gene="dnaA"
                     /locus_tag="LP245_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBL1519243.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19747..20877
                     /gene="dnaN"
                     /locus_tag="LP245_001314"
     CDS             19747..20877
                     /gene="dnaN"
                     /locus_tag="LP245_001314"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBL1519244.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21106..21348
                     /gene="yaaA"
                     /locus_tag="LP245_001315"
     CDS             21106..21348
                     /gene="yaaA"
                     /locus_tag="LP245_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBL1519245.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21335..22459
                     /gene="recF"
                     /locus_tag="LP245_001316"
     CDS             21335..22459
                     /gene="recF"
                     /locus_tag="LP245_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBL1519246.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22456..24402
                     /gene="gyrB"
                     /locus_tag="LP245_001317"
     CDS             22456..24402
                     /gene="gyrB"
                     /locus_tag="LP245_001317"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBL1519247.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24422..26893
                     /gene="gyrA"
                     /locus_tag="LP245_001318"
     CDS             24422..26893
                     /gene="gyrA"
                     /locus_tag="LP245_001318"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBL1519248.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27129..27428
                     /locus_tag="LP245_001319"
     CDS             27129..27428
                     /locus_tag="LP245_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBL1519249.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27478..27990
                     /gene="ssb"
                     /locus_tag="LP245_001320"
     CDS             27478..27990
                     /gene="ssb"
                     /locus_tag="LP245_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1519250.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            28016..28252
                     /locus_tag="LP245_001321"
     CDS             28016..28252
                     /locus_tag="LP245_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBL1519251.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28395..30368
                     /locus_tag="LP245_001322"
     CDS             28395..30368
                     /locus_tag="LP245_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBL1519252.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30374..30826
                     /gene="rplI"
                     /locus_tag="LP245_001323"
     CDS             30374..30826
                     /gene="rplI"
                     /locus_tag="LP245_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBL1519253.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31100..32467
                     /gene="dnaB"
                     /locus_tag="LP245_001324"
     CDS             31100..32467
                     /gene="dnaB"
                     /locus_tag="LP245_001324"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBL1519254.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33247..34539
                     /locus_tag="LP245_001325"
     CDS             33247..34539
                     /locus_tag="LP245_001325"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBL1519255.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10562 a         6741 c         6851 g        10525 t
ORIGIN      
        1 ggtttgtctt actttgttca gttttcaaag gtctacttca tcaggagtgt ttcccgattc
       61 gtttttggct gccgtagcaa cttttatatc atatcagaga gacaagtaat tgtcaactct
      121 tttttaaaag ttttttcgat ttcgtttttc gaaatcttcc agcaactcat ttatcataac
      181 ttatcgtttg ttatttgtca agaacttttt tgaagttttt ttcgatagaa tcaagcttcg
      241 caagtggttc ttttttaacg actcagttat cttatcatgt catttccaac atgtcaacaa
      301 cttatttttt attatttaat aagttattgg tgttcttttg aacaaataat aatatatcaa
      361 catcacatgt gaaagtcaat aagaaaatgc ttatttatca acatttctag cttacatgat
      421 cattggttag ttctggtcct ttttcgttcg tctttataac tccgagagac gtaaaatcct
      481 tttgttttca gtttaatgtt catgttcttg tcttattcac accaactaga tgtctcacct
      541 tctaaaattt tccttaacaa agtgctgctt ttatctattt ctgctttttt ttgctagaat
      601 aatagtaaca atatgactct ggaggattta tttatgaaaa ttttgattgc tgacgatgat
      661 aaagaaatcg ttgaattatt aagtatctat gttcacaatg aggggtatga agcagtaaag
      721 gcttatgatg ggaaagaagc attatctaaa atcagaacaa tccctgatat tgaattactt
      781 attttagata tcatgatgcc tgagatggat gggatgcaag tagtgaaaga gctacgaaaa
      841 gaatcccaaa taccaatcat tatgctgaca gcaaaaacta ctgatatgga taagatcaaa
      901 ggactggtcg ctggtgcaga tgattatgtg accaagccat ttaatccgtt agaagtaatg
      961 gctagagtaa agtctttatt acggcgtaca aaaatgcaga ttgccccaga tcagcctgat
     1021 gtattagaag taaatgcatt aatcatcaat aaagactctc atgaagttaa aacaatcgat
     1081 gggaaagaaa tccagttaac agctttggaa ttcggtatcc tctacttgct tgctagtcat
     1141 cctaatcgag tatttagcgc ggatgaaatt tttgagcgtg tttggaaaca agaaagtatt
     1201 gtctctgcta aaactgtcat ggttcacgtt agtcatttaa gagataagat tgaagaagca
     1261 actggtggtg aaaaagtcat tcaaaccgtt tggggagtgg gctataaaat tgacgcaaga
     1321 tagtaaacga gcaactgaaa aacgccgtcg gatcaatttg acttcaaaag aaatcagcga
     1381 attgttagcg gaaggaatca tcacgattat ccttttgctt ctattaaatg tttctattct
     1441 ggttgttatc agttcggtga tcaacagttc accttctttg acgaatgcga tttgggattc
     1501 aaagaatatt tttgcagaac gattgaacac tgatttgttc tggaacggcc ggaattttat
     1561 tattcccttt ttctttctat tagatattgg tgttttgtat tggcgcttga ttcgaagata
     1621 tcgccaaatg caattgcggc atatcatcag cgaacttcac tacatcgcaa acggaaatta
     1681 tgatcatcgt atcccttttg aactgagtgg tgacttaagc cgagtggtaa caagtatcaa
     1741 tggattggtg gatagtaccg tagcagcgat tgaagacgaa cgtaaaatcg aaaaatcaaa
     1801 agatgaattg atcacgaatg tcagtcatga tatccgtacc ccactcacgt ccatcattgg
     1861 atacctagga ctgatagaag atggccagta tcactcagaa gaagatcttt taaagtatac
     1921 gcatactgct tatatcaaag caaagcagat gaaatcttta gtggacgact tatttgaata
     1981 cactaaggta cgccagcctg ctgtcccggt gaatttttct gcctttgaca tgatccagtt
     2041 gatcgaacag ttagcagctg attttgagtt ggaagcttct aaaaaaaata tccaaatact
     2101 tgttcaatca aaagtagact cccttatcat ggatggcgat accgaaaaac ttgtacgtgt
     2161 cttcaataat cttttgacga atgcgttgaa atacggaaaa ggagcaacga agatcgtaat
     2221 cgaagtagaa cgtatcggtt cagaagttgt tgcaacagtc aaaaataacg gagcaatgat
     2281 cccacaacag gcaatcgata atctattcga ccgtttttat cgtgtagaag aatctcgttc
     2341 acaagcaact ggaggaactg gacttggttt agcaatcgct caaagcattg tggctttgca
     2401 cggcggatac atttatgcaa aatcagataa gcaatggact tctttcatca tgcaccttcc
     2461 aatcaagaaa aatgaaaaat tacctattga tacacaggaa gttattgacg aaagctgaaa
     2521 tattcgctat tcttattaca attattagaa taaatgaaaa acacagaacc cagtacactt
     2581 tattcttttt cagagagctg atggcaggtg taaatcagca aaggataatt tggaagttcc
     2641 agttcgttta cgtgcccttt cgaaataaga aaggtcggtt caacagccgt tatgtgttca
     2701 acaagtgcag ctgacgctga acttgggtgg taccgcgaat ttcagactga ttcgtcccaa
     2761 gaataatggg atggatcagt ctttttttat tttcaaaaag gaggaaatca tatgttagat
     2821 gtaaaaatga tgcgacaaaa tattgaagaa gtacaagaaa aattgatgac tcggggcgta
     2881 aaaaaagaaa cattagctga attcatggaa ctagatgaaa atcgtcgtaa gctactagtc
     2941 aaaagtgaag aattaaaaaa atatcgaaat gatgtttctg ctgagatcgc ccaattgaag
     3001 cgtgcaaaag aagatgcttc tgctaaaatc gctgaaatga aagaagtcgg tggcaacatc
     3061 aaagcattgg atactgaaat tgctgaagtg gatgaaaaat tgaaacaaat tgcaactact
     3121 ttgccaaacc ttccccatga ttctgtgcca gttggaacag atgaagagga caatgtagaa
     3181 atccgtcgtt ggagcgaacc acgtacattt gcttttgaac caaaaccaca ctgggaaatt
     3241 gcagaaaatc ttgatatttt agattttgaa cgtggcgcaa aagtagccgg tagccgtttt
     3301 gtctattaca aaggattagg tgctcgatta gaacgtgctg tctacaactt catgcttgat
     3361 cagcatattt acgaacacgg ctatactgaa atgatcactc cttatatcgt caacagtaaa
     3421 gcgatgtttg gtacgggaca atttccaaaa ttcaaagaag atgttttcca attggagaat
     3481 actgatctaa cattaatccc aacagctgaa gtaccattaa ctaactatta taatgatgaa
     3541 attttagatg gtgcagattt acctatttat ttcactgcac taagccctgc ttttcgttct
     3601 gaagccggaa gtgctggtcg ggatacacga ggactgattc gtcttcacca attcaataaa
     3661 gtagaaatgg tcaaattttc ggatgtagag cattcttacg aagaattgga aaaaatgaca
     3721 gctgatgcag aagatatctt gaaaaaattg catttgcctt atcgtgtgat ggccttatca
     3781 actggagaca tgggcttttc tgcagctaaa acttatgact tagaagtatg gatacctgca
     3841 caagatactt atcgtgaaat cagttcttgt tctaactgtg aagatttcca agcacgccgc
     3901 gcaatgatcc gttatcgcga taatgatgga aaaatccact atactcatac tctgaatggt
     3961 tcaggacttg cagttggccg tacagtagct gccattttgg aaaactacca aaatgaagat
     4021 ggttctgtca cagttccaga agcgctcgtt ccttatatgg ggaatctgaa agttattaaa
     4081 taaagaggct gtgaaaaagc cgcttagttt cgagtattaa gaaaaatttt gtgaaaatgg
     4141 ctttccacat ttttgcataa attggactta ataccgagaa actggctttt gaacaccatt
     4201 tatcgagagg ttgtgaaatc agcgaattaa cctgagtatt agagaaaaaa atggaaaaat
     4261 agtccctcat attttaccgt ttgttgaact aataccgagg gtcagctgat tgaacaccgt
     4321 ttagtggaga ggtcgtaagc ctacccccca gctcctagtt acaaggacaa attcaaaaaa
     4381 cagctcttca tattttatga atgttgtact tgtgattcgg aggtggcaag ggaacactgt
     4441 ttattcaaaa agaggctggg acagaagcgt ttaactccaa gaaataagaa gaaattcacg
     4501 aaaattgctt ttcaaatttt tgtgaatttc ttcttatttc cgaaggagtt gcttctactt
     4561 ccgccgttta tacgtgttta gagcgtgaga caaaagtgtt ctttactttt gtcccacgct
     4621 ctttaatgtt tttaagattc aactgaatag tttggtgctt cttttgtgat ttgtacatca
     4681 tgagggtgtg attcttttaa tccactgccg ctcatttgga taaattgcgc ttcatcacgt
     4741 aattgctgta gattggctgc cccaacataa cccattcctg aacgcaaacc gccgatcatt
     4801 tggaaaataa tatctgcaac acttccttta taagcaaccc gaccttcgat tccttctggt
     4861 actaatttat ttgcttcatt gacactacct tggaagtaac ggtcttttga acctttttcc
     4921 atcgcgccta atgagcccat acctcggtat gttttgaatc gacgtccttg gaagatttcg
     4981 aattcacctg gtgattcatc tgtccctgcc aacatacttc ctagcatcac tgcatgtccg
     5041 ccggcagcta atgctttgac gatgtcacca gaatatttga tccctccgtc tgcaataatc
     5101 gctttgccat attgacgagc aactgatgct gcatcataaa tagctgtgag ctgaggtaca
     5161 cctacaccgg ctaccacacg tgtcgtacaa atcgatcctg gtccgatacc aacttttacg
     5221 acatctacac ctgcatcata taaagctttt gtcgcttcag ccgtcgcaac gtttcctgca
     5281 atcaatgttg catctgcaaa agttgaacgg atttcttgaa tttttcggat cacacctgca
     5341 ctatgtccat gagctgtatc gatgatgatt gcatctgccc ctgcttctaa taaagcattc
     5401 gcacgctcaa atgtatcgct tgttacacca acggctgctg ctacaagcaa tcgaccatgt
     5461 tcatcttttg ctgcatttgg aaattcgatc actttctcga tgtctttgat cgtgatcaat
     5521 ccgcttaaac gaccttcgtt atctacgatt ggtaattttt cgattttatg tttttgcaaa
     5581 atcttttctg catcttttag agaggtacct actggggcag tcactaagtt gtcttttgtc
     5641 atcacatcag caatcggcat gtgataatct gttacaaaac gcatgtcgcg gtttgtaatt
     5701 atccctacca attttctgtt ttcaagtgtt tcaacgattg gcacaccact gatacgatat
     5761 ttgctcatca attcttctgc gtctgctaca agatgctgtg gcgttaagaa gaacggatca
     5821 atgattacgc cactttcaga acgtttgact tttcttactt catccgcttg ctggctgatc
     5881 gtcatgtttt tatggatcac acctagtccg ccttgtcttg ccatagcaat ggccatcttg
     5941 ctgtcggtaa cagtatccat acttgcactg atgattggaa tattcaactt aatattttta
     6001 gctaattgta cgctcatatc cacttcgttt ggtaacacgt gactttctgc tggtatcaat
     6061 aagacatcat caaaagtaaa tccttttttc gtgaactttg tttcccagtt ggacattttt
     6121 agtaccactc ctctaattta gtttatctat taaaataatt gattttttca tttaagtcaa
     6181 tgatctactt ggaatcaagt tagctttctc atagaatacc aatataaagc gtttacatct
     6241 gtgtatatta aaagagattg taaaaaagct gtcctgcatc aagtaataag aacagccaat
     6301 caaaaacagc ttctcatgtt tttgaattgg ttgggtttat taccgcagat gcaaactttt
     6361 gaacaccgtt tagtggagag gctgtgaaaa agctgcttag tttcgagtag taagaaaaat
     6421 tttgtgaaaa tggctttcca catttttgca taaattggac ttaataccga gaaactggct
     6481 tttgaacacc gtttatcgta aaaagggact gtgacaagac ttttgtcaca gtcccttact
     6541 attatttaac tatggataaa caaaatgagg ttctttacta cccctagata tctagcaaaa
     6601 tagctgatct ttttgctagt ttatcttctt gggacggata aacttccaat aatcccgtat
     6661 tttttcttca agtagtaacg gattgctaaa gcagttgccc cgataatgat aactactact
     6721 ggatctaata ctggattgat aactggtggc aatagtgttg tcgcagaaaa cagtacgacc
     6781 caaagaagtg tcgttccacc taggataagc aatgtcttac ccattcctgg tttcttgctt
     6841 cgatctgctc cgggatattc atattgatag atgtatttgt acatcatata aaagacccag
     6901 ccaccgattg cagaacctag aacgagtgta gaaaagccat aagctggcgt tgttccacgt
     6961 gaaaacaatc cggtaatcgc aatcatgata cttaatagac caagcaacag caacgtatta
     7021 tctaaccaca tcaataaagg ggtggatgaa ttttttactt ctgctggctt attgatgatt
     7081 gcttccgttc tttcagagac tgtcccaaac aattgacggg ctgttcttcc gcctttttgt
     7141 tctgcaacta aagtaggcag aatgtcatga agggctttta ctttttcttc ttcagacaaa
     7201 ttcgctgctt ctaaagattt tttcaaatca aaaatgtact gttgatttct tttggttaat
     7261 tttgtttcta aactattgtt ttcttttacg attgctcgta attgttctgg ttccattatc
     7321 taatagtcct ccttagccgt tccttttctc aacggtcgtc acaaaagaca ttctaccata
     7381 ttctacagct agtttgatag cccttttaca cattaaagcg gaataacatt acgtcgccgt
     7441 cttgtacgac ataatctttt ccttctaatc gaacacgtcc agcttctttt gctgcatgca
     7501 tgtttccgta atgatccaag tcttcaaaag agacagtttc tgcacggata aatccgcgtt
     7561 cgaaatctga atggatgatt cctgctgctt gtggtgcttt gattcctttt ttgaatgtcc
     7621 aagcacgtac ttcttgttcc ccagcagtaa agtaagtagc taagcctaac aaatcataag
     7681 cagcacggat caactgatcc aaacctgatt cttcgattcc taaagcttct aaaaattccg
     7741 ctttgtcttc ttcatctaat tctgcgattt cttcttctgc acgagcactg accacgatca
     7801 cttctgcatt ttcttctgca gcaaagttgc gcacttcttg tacataatga ttcgcgtctg
     7861 catctgctac gtcatcttct gagacattgg ctacataaag aattggtttt gtcgtcaata
     7921 aaaatagtga tttaacgatt ttttgttctt cttcagtaaa ttcgatcgtt cgggcagatt
     7981 ttccttcttc cagtacaggt ttgattttat ccagtacagc tagttctgcc actgcatctt
     8041 tatctttggt tttagcaact tttgctacac gagtatagcg tttgttgata gattctaagt
     8101 ctgctaacac tagttccaag ttgatcgtat caatatcttc tagtggatca acacgtcctt
     8161 ctacgtgagt aatattatca tcatcaaaac agcgaacaac gtgacaaata gcgtctactt
     8221 ggcggatatg gcttaagaat tgatttccca aaccttctcc tttacttgcg ccttttacga
     8281 ttccagcaat atctgtaaat tcaaaagtcg tcggaacagt ttttttcgga tgtacaagtt
     8341 ctgttaagcg ttgcaaacgc cagtcaggta cttctaccat ccctacgttg gggtcgatcg
     8401 tcgcaaaggg atagtttgct gcttctgctc ctgcttttgt gatcgcatta aacaaagttg
     8461 attttcctac gttgggcaac ccaacaattc cagcagtcaa tgccataaat ttattcactc
     8521 tttctctgca tttttttcaa ttactttttt taatttcttt tcaaaatctc gacgggtcat
     8581 catgacgata tgtccgcaat tcatacatct gattttgata tctgcgccca ttcgaatgac
     8641 ttcccagcga ttcgtctggc aagcgtgagg ttttttcatt tcaacgatat cgtgcaagtc
     8701 gtacataaaa atagcctcct ttttgtttat tcttcatcaa attgaatatt caagatatca
     8761 agaattcgag tcaaatcttt ttgagaaaga tattcaatct cgatcttacc tttcccattt
     8821 ttttcttgga tagctacact tgtaccaaat ttatccatca aacgatcttc gctttctcgg
     8881 atataatatg gtttttcctt tgctagcctt gggatttttt tcttttcttt tccatcattt
     8941 tgatttaact cagaaacaag ctgttccagt tggcggacag ttaaattttc agttactgca
     9001 cgattggcta atttcaagat caatgtttta ttttttaaac ctaacagcgt acgggcttgt
     9061 cccatagata aacgctgatc ttgtaccatt tccttgacaa gatccggtaa agaaagcaag
     9121 cgcaaataat tggcgatata aggtctgctc tttcctaaac gactagctac ttctgcttgt
     9181 gttagtttca ggtttttcat cagcatctca tatgcttctg cttcttctaa cggattcaga
     9241 tcttctcgct gcaagttttc cagcactgct acttgcatca tcgcttcttc gtcaaagtct
     9301 ctaacgatag cagggatcgt ttctttttca gctagtttgg acgctcgaaa acgtcgctcc
     9361 cctgcaataa tctcatatcc ttttactgcg gaacggcgta cgatgatggg ttgaaagaca
     9421 cctgattgtt caatagaatt agctagttcc tgcaaagata cttcttcaaa tgttttacgg
     9481 ggctgatacg gatttggtcg cagctcattc aatggtagct ggacaacggt atcatctttt
     9541 acatccaccg tctctaagtt ttctaaatct tgaaacagtg catcgattcc tcggcctaat
     9601 cctttacttt tcttcacgac ttaccacttc ctttgccaat gcttggtaga cttcagctcc
     9661 tcgagaacgt ggatcgtagt cgatgatcgg ttttccatga ctaggtgctt ctgataaacg
     9721 aatatttctt ggaatgatcg tttcgtaaac tttttcgcgg aagtatttac gtacttcttc
     9781 tacgacttca tttcccagat ttgttcgtgc atcatacatt gtcagtaaga ctccctcgat
     9841 ctctaattct ggattaaagt gtttttggac taaacgaacc gtattcagta attggcttaa
     9901 tccttccaat gcgtaatact cacactgaac aggtatcaaa atcgaatcac ttgctgtaaa
     9961 tgaattgatt gtcagatggc caagagaagg cgggcaatcg atcaaaatat aatcatactg
    10021 actgcttact tctgctaaag atccttttaa tcttgattct cttgccatca ttgacgtcaa
    10081 ttcgatctct gctcctgcta attggagagt cgcaggcaca atactcaaat tttcgtgttc
    10141 agtgatcaaa gttgcctcat caattggcaa ttcattgact agaacatcat agatgtctct
    10201 tgtcacatca ggttttctga tcccgacacc actggtagca tttccttgtg catccatatc
    10261 cactagcaat acttttttgc caaggctagc aagacaagca cctagattca ccgtcgtcgt
    10321 tgttttgccg acgccacctt tttggttcgc aacagatatt atttgtgcca tctcttctcc
    10381 tcctatttga ttggctgctt attaggcagt ccgggctttc ttgggtattt ctttggggtt
    10441 ggtttctttt tttgaataac gatgatatgc cgttgatcag agacattcgg caaggtaacc
    10501 gcctcttctt tgaggaattt accacctaat aaagcaatcg cttgttttgc ttctgtcaat
    10561 tcctcttcac tttttgctgc tttcaatgca taaaaatagc cttcttgttt agccaagggc
    10621 aaacacaatt ccgctaacac attcaaacga gcaaccgcac gagcagtgac aaggtcaaat
    10681 gatgcacgaa agtgaggatt ttgcccaaat gtttctgccc ggtcatgata taaggaagca
    10741 tcgattccta ataatcgggt taactcagat aagaaggtta ttcgtttatt cagagaatca
    10801 acgatcgtta tctgcagttc tggaaaggca atttttaaag gtatgctagg aaaccctgcc
    10861 cccgaaccaa catcgcataa agataaaggt tgcgtaaagt ctacttcaaa tgctaatgta
    10921 agtgaatcgt aaaaatgctt cagatatacg tctttttcat ccgtaatagc tgtaaggttc
    10981 atcttttcgt tccattcgac taatgtccga taataaatag cgaattgatt catttgatga
    11041 tcggtaagct ctatcccttt ttctgccaag gattggcgaa attcttctgg tatcataaat
    11101 attcctttca ttgtgaaaca gcaattgttt cacagattct ctccctactt taacgcaaaa
    11161 tctctagaca tgcaatcctt ccatatggat tcttaaaaat ttgaaaagta agaaaagccg
    11221 atagactttt tctttctagt atgactcata aaatatacac agaagagaga actagctttg
    11281 agcaatttct gcaaaaacta gttctctctt ctatttatta ttacgtatta cgctggttca
    11341 ctgactttcg caatcttccc ttgttcgata tagaccatta ggatacttag gtctgcaggg
    11401 tttacgccac tgattcggct agcttgggca attgtttctg gttggatttt ctgcaatttt
    11461 tgttttgctt ctgttgctaa tccgttgatt gctgcgtagt cgatgttttc tggaatcttt
    11521 ttcgcttcca tgcgttttaa tttttctact ttttccatgg cttttttgat gtagccttca
    11581 tatttgattt ggatttctac ttgttcgatt tcttttcgtg tcaattcttc attttctgga
    11641 ataaaccgta gaagttctgc ataagtaatc tcaggacgtc ttaaaaagtc gcttgctagt
    11701 acaccatctt ttaatggtgc cgcattaatc gttgctaaaa agtcttggac ttcttctgtt
    11761 ggtttgattc gtacattcat caaacgtttg atttcttgtt caactgcttc ttttttcttc
    11821 aaataattct tgtattgatc ttcttttact aagcctacac ggtgacccat ttctgttaat
    11881 cgcaaatctg cattatcatg acgtaaaagc agacggtatt cagcacgtga agtcagcaaa
    11941 cgataaggtt cgttcgttcc ttttgttacc aaatcatcga tcatgacacc gatgtaaccg
    12001 tcacttcgtt tgatcactaa aggttctttt ccctgaactt tcaaagctgc attgataccg
    12061 gcaatcagcc cttgtccagc cgcttcttca taaccgcttg taccatttgt ttgtccagct
    12121 gtataaagat tttcaacgac tttagtttct aatgtcggac ggagctggtg tggctctact
    12181 acgtcatatt cgatagcata tcctgtacgc atcatttcta ctttttctaa tccagcaata
    12241 gaatgaagca tgttgacttg aacatcctct ggtaaagaag tagataaacc ttgaacatag
    12301 acttcttccg tatttaagcc ttctggttcc aaaaataatt gatgacgtgg tttgtctgca
    12361 aaacgcacga tcttatcttc gatggatgga caatagcgag cgcctacccc ttcaacgatc
    12421 cctgtaaaca ttggggcacg atgtaagttg tctcgaataa tttggtgagt cgtctcacct
    12481 gtataggtca gccagcaaga ttcctgatct agtttatagg cactatctgg tgtgctgaag
    12541 ctaaaatgat tcggctcttt gtcaccaggc tgctcttctg taacagaata gtcgatcgta
    12601 cttgatttta ctcgaggcgg tgttcctgtt ttgaaccgtt cgatagcaaa gccaagttct
    12661 tttagatgat tcgctagtcc aatagaaggt tgagagttat tcggacctga tgaatatttc
    12721 aattcaccga taatgatttc tccgcgaagt gctgttccgg ctgtaataac aactgctttg
    12781 gcccggtagc tcgctcctgt ggacgtcact actccatgac aaacaccatc ttcgacgatc
    12841 agttcttcga cgattccttg tcttagcgtc aaatttggtt ctttttcgat cgtatgtttc
    12901 atttctgttg aataagcatg tttgtctgct tgtgctcgca atgctcggac agctgggcct
    12961 tttcctgtgt tcaacatacg catttggata taggttttat cgatattctt acccatttct
    13021 ccgcctaacg catcgatttc tcgaacgaca acgcctttag ctggtccgcc tacagaagga
    13081 ttacatggca tgaatgctac catgtccaaa tttattgtca gtaataatgt ttttgatccc
    13141 atacgtgcag cagcaagtgc agcttctgaa ccggcgtgtc ctgcgccaac aacgatcacg
    13201 tcatacgcat ctgcttcata atgttccaat cgtttgttcc tccttttatt ttcctaaaca
    13261 aaattgactg aataattgag tgattagctc atcttgtaca ctgtcgccga caacttctcc
    13321 tagatagtcc cagcaacgcg tcatatctat ttgaacgaga tccacaggca ttcctgaatc
    13381 aatacctgca atgacttctt caagtgagag ggaagctttt tctaacaacg cgatatggcg
    13441 ggtattagaa acataagtag cgtctctttc tcctgtttct ccgctgaaga ataaatcaga
    13501 aatagctgat tccaaacgat ctagtccgtc gtttttagct acggaaattg aaaaaactgg
    13561 ttcattttcg atcaatttct tcaatttttc ttgttccagc tgtgctggca aatctgtttt
    13621 atttagaaga atgatccgtt tcaatccact tgtcgcttcc aataattgtt catcttctgc
    13681 tgtcagtggt tcgctttggt ttagaacaag taagatcaag tctgcttctg ctaatgcttt
    13741 tcggcttctt tcgaccccga tccgttccac cacatcttct gtttcccgaa ttccagctgt
    13801 atcgattagc ttgagcggta ccccccgaac attgacatac tcttcgatta catctcgagt
    13861 cgttcctgca atatccgtaa cgattgcttt ttcttctctt aacaaatggt ttaacaaact
    13921 tgatttgccg acatttggcc ggccgatgat tgccgtactt aacccttccc gcagaacctt
    13981 cccttgcttg gatgtagcaa gtagcgcttg gattctttgt tggatcatct gcgctttttc
    14041 aagcaataac ttcgtagtca attcttcgac atcatcatat tctggataat caatatttac
    14101 ttctacttgt gctaatgtct ctaaaatctc ttgtctcaat gagcggatca aagcagacag
    14161 attgccgtct aactgattaa gagctagtcc cattgctttg tctgtttttg cccgaatcaa
    14221 atccatcaca gcttctgcct gtgaaaggtc aacacgacca ttcaagaatg ctcgttttgt
    14281 gaattcgcct ggctcagcta atcttgcacc ttctcttaac aatagctgca aaatttgatt
    14341 gactacaacg atcccaccgt gacaattgat ttctactaca tcttcccgcg taaatgtctt
    14401 tggtgctctc atcacggaga ccatgacttc atcgacaagc tgattgctct tgggatcaac
    14461 gatatgtcca taatggatcg tatgacttgg tacttctgat aatcgtttgt ttccagattg
    14521 ataaacttta tctgctagtt gcacagcttg atcgccactt aaacgaacga tactgattgc
    14581 accttctcca ggtggggtag aaattgccgc aatcgtatca aattctaaag taatttcagc
    14641 cattttttca cttccttttt cattttgcgc acaaaaaaag tgcccactcc accctttatg
    14701 cacaataaac ggtgaacttc gcactttgac tgcttgttct tgattaaatt ctggtcatag
    14761 attatcacac ttgctataag gaatcaagtg tttaaaacaa ttagatgaag ttgagcctgt
    14821 tctgcttcca ttaccttata tttaattgtc cttggatgtc tctttgcgtt ctttggttta
    14881 ttcgaagaga agatactgta taaacaaggc tttatctttc ttaaaaaaaa cggtacacta
    14941 aatggtagcg ctatctaaac tatacacttt tgaaaggaga aaatatgtga gcccgttcag
    15001 atctgctgca ttggaagaag aaagtgaccc tcggatcaac gatgtcgttt tatctacagg
    15061 gaatatcaac cagaaatata tcgtccgcga tatcgttttt gttgtggaat gcttagaagc
    15121 tgatttgttt gacccatctt ttcccaaaga tgaccttttc ttaacaacga agaggaaatt
    15181 aaagacgaag gtacttgaat atggtgcgaa tgcagtaatc aactgtcatt ttgagtatca
    15241 gcaaaaaaaa cgcgacggaa agtattttct ggaacttttt gcttatggaa cagtgatcca
    15301 atttatccaa acaacgattg gttaaatgaa acagacaaaa aaagcggatc aaaactgaag
    15361 acagtttcga tccgcttttt tctatcaaag ttagtgacta cttcatcgta tactctgata
    15421 agaatgattt ctagtaaaat atacttggtt tgaaaaactt tgtcaacgtg atttattcaa
    15481 aaagtaatgg aatcaataat attttttagc aggttctact actaaataac gataaggttc
    15541 ctcaccttcc gaatgtgttt ttacatgttc atctttgctt aatgcagcat ggatttgttt
    15601 acgttcaaat gcaggcattg gttctaagaa aacaggctgc cctgtccgtt ttactttttc
    15661 agccgtgcga tcagctaaac gctgaatgat ctcttggcgc ttttcacggt aattgcctac
    15721 attgactact acagacagct tatttcttgc taaacgatgg atgaagactt gtgccagata
    15781 ttgcaatgca ttcagtgttt ttccatgttt cccaatcagt atgccttgct tttgtgtttc
    15841 taaatggaaa acaaccatat tatttgattc tctttccatt ttgacaagag ctggagcatc
    15901 aagctgtttt gaaatttcag taagataaac tgccaattcc gttaaagctg cttcatcacc
    15961 tagctcactt acttcttctg ttttttcttc aagaatcgtt tcgttgacta cctcgatctc
    16021 agctgttggt tcttcttcca aaatttcttc tacagtctgt tctactgttt cagaaacttt
    16081 ttcgctgata cttggctgga tcgaaagccg tgcattcttt cgacccattc ctaggaaacc
    16141 tttttttcct tcttccagta tttcgatttc gacttggtct ttggccaaac ccaaatcagc
    16201 cagacctagt tggacagctt cgtctattgt tgcagcttca taaatcggca ttagcattac
    16261 ctcccctatt atttccgttt tttcttagga ttcattgctt tcttaagagc acgttctctt
    16321 tcgcggattc tccgtgcttc ttcttcacgc tcttttcgaa ttttgaaagg gttgttgatc
    16381 agcagcgttt gtacaacttg gaaggcattg gaaactaccc agtataatga aagaccgctg
    16441 gctaaattga cacccatcac taaaatcatt acaggcatca cgaaattcat gatcttcatt
    16501 gatgcattcg attcaatttg actcatgcta gataaatacg tacttgcaaa agtaaagatt
    16561 gctgctaaaa tcggcaaaat aaatgttgga tccgcgttcc ctaagttcaa ccataagaaa
    16621 tgcccttgtt tcaactctgg tacacgtgaa atagattgcc ataacgccat caagattggc
    16681 atttgtacta ataaaggaag acaaccagca tatggattga cgccattttc tgcatataaa
    16741 cgctgctgct cttctcttaa cttactttgt gtttccggat ctcttgaact atattgttgc
    16801 tgcagtgctt ttaatttcgg ttgtaattct tgcgttttac gcatgctctt tgtttggaaa
    16861 tgcatcaacg gcaataggat cacgcggatg atcagtgtaa ataaaatgat ccctatccct
    16921 gcattaccaa atgacaacgc cttgatcgcc tcagcaaagt aataaacaat ataacgatcc
    16981 caaattcctg tactctgtgc gctgacttcc ccagttccgc aaccggataa gacgatgacc
    17041 aaactaacga taccggccat caaaagtaaa cgtttgtatt tcttcactta ctcttttcct
    17101 ctctgtcgat tatttttgca agttttaaga cgtggactaa attggagcga acctcatcat
    17161 aagtcaaccc cttcacactt ggtctagcaa tcacaataaa atccaactcc ggatcaattt
    17221 cttcttttat agaataaact gctgctcgga tttttcgttt gacttcattg cggtttaccg
    17281 cgttgccgac cttttttcct acagataaac caactcgaaa atgaggctgt cccggttttt
    17341 ccaaacggta aacgacgaat ttgcggttag caaaagaatc tcccgtatgg aacacggctt
    17401 gaaactctcg ttcttttttt actcgatacg cttttctcat tagttttctt tccttttcta
    17461 tctctcactt acgctcataa tcataccata attacgattg tcctttcatc atttccctaa
    17521 aaaagagtat aaaaaaaacc actgaaaccc cagtggccta agctgaaaga acttttcttc
    17581 ctttgcgacg acggctagct aacacacgac gtccattttt agtactcata cgtttacgga
    17641 atccgtgaac tttttgacgt ttacgtttat ttggttggta tgttcttttc atatattcca
    17701 cctccaaaat gttcttatct attttataaa cacagacata ctttgatagt ataacgacaa
    17761 agtagtgatt ttgtcaatat aaaatagaag atcgattgtt aaaacttatc cacaagatta
    17821 tttttttcta tgggaatcct atgtggaaaa agttatgcac agggattatc cacagataat
    17881 aaaaggctgg ttttacacag aaaacacacg tgtaaaaaaa gtaatccaca atcaggcgat
    17941 ttcctgtgta ttccgtctcc taactattgg tatatctgta ttttttatcc acagacgcaa
    18001 gaggaaatct attggttttt acgagttttc cacctgtgca ttagtggtgt ggaaaacttt
    18061 ttttgacaac tgtgtttttc tcttttttct ttttgtcgat tgtgtggata attgtaatta
    18121 aaaaattttt ttcttcggtt tctgtggaaa actattgaaa aaaatgctaa attagtacta
    18181 gttattcact ttttaatgaa ggaggaggcc ttatatggta tccctcgatg ctttatggaa
    18241 tgaattaaaa gcaacatacc aaaaggattt atcgcctgct agctataata catggatcga
    18301 aacagcgaac cctcgaaccc ttgatcaaaa ccagctcgtt gttgaggttc ctagcaagat
    18361 tcataaagaa tattgggaaa aaaacctggc gacaaaaatc gttgaagtcg gttatatgtt
    18421 atcaggaaat gagattatcc ctcgctttat tactggcgaa gaagcagagc aagaagaagt
    18481 tatagaagaa aaaaatccaa aagttgtggc acctagtccg ctaaaaaaag ccatgctgaa
    18541 ccctaaatat acctttgata cgtttgtcat tggtaaagga aaccagatgg ctcatgcagc
    18601 agcgctcgtt gtagcagaag atccaggttc tatttataac ccgctcttct tttatggagg
    18661 cgtgggactt ggtaagactc acttgatgca tgcaattggt catcaaatgc tgcaaagtca
    18721 gcctaatgcc aaagtaaaat atgtaagcag tgaaactttt gctaatgatt tcatcaattc
    18781 gatccaaaac aaaacagcag aagagttccg tcaagaatat cgaaatgttg atttactgct
    18841 agtggatgac attcaatttt ttgcagaaaa agaagctacg caagaagagt ttttccatac
    18901 tttcaatgcc ttgtacaatg aagggaaaca aatcgtacta accagtgatc ggttgccaaa
    18961 cgagattccg aaactgcaag aacgccttgt ttctcgcttt gcatgggggc tgtctgttga
    19021 tattacaccg ccggatcttg aaacaagaac agcgatttta cgtaaaaaag cggcggctga
    19081 acgtctagag atcccagatg acacactaag ctacatcgca ggacaaattg attctaacat
    19141 tcgtgaatta gaaggtgcgc ttgttcgagt gcaagctttt gctgcgatga atagtgaaga
    19201 tatttcgact agtctagctg cagacgcact gaaaacgtta aaatcaggaa aaggacatcc
    19261 tcaattgtca atcctgcaga tccaagaaga agtggcaaag tattatcaca tccaattgaa
    19321 agatctcaaa ggaaagaaac gcgtcaaatc tattgttgtt cctagacaaa tcgctatgta
    19381 tttggcacgt gagctcacag ataattcttt accgaaaatc ggagctgaat tcggtggcaa
    19441 ggatcataca acggttatcc atgctcatga aaaaatccag cagctgatgg attctagtgt
    19501 cagtatgcaa aatgaagtat cagaaatcaa aaacttttta ctaaattaat ttgtcgattc
    19561 tatcaactga aaatagcatg tggataaaag aaaaaaacgt tcaaaagtta tacacacttt
    19621 ttccacagct gttttttcgt ttctctctta cgttttttga gttttccaca gaatcaacat
    19681 gccctattac ttttattatt ctttttaact aataataaat aaacaaacat tcaaaggaga
    19741 tacatcatga aagttacttt aaaccgagct agctttatgc aggaattgca aactgttcaa
    19801 cgagctattt caagcaaaac cacgatccct attttgacag gtgtaaaaat cacactgaca
    19861 caagaaggtt tgactttgac ggggagcaac gctgatatat caattgaaac ttttttgtct
    19921 gttgaaaacg aaaaagcaaa tatgcaaatc gaatctactg gttccattgt tttacaagca
    19981 cgtttcttta gcgaaatcat tcggagactt cctgaagaaa catttacttt agaagtttta
    20041 gaaaataaac aagtagcgat cacttctgga aaagcgaatt ttatcgtaaa tggattagat
    20101 gcagataact atcctcatct tcctgttgtc gaaagccata accagatgaa attacctgta
    20161 cacgtattga ctaaactaat caacgaaaca gtttttgctg tctcacaaca tgagagtcgt
    20221 ccaatcttga caggtgtgca tttcatttta tctgataatt ctttattagc tgtagctact
    20281 gattctcacc gtctaagtca acgcgtgatt ccagtagaac aagcggctga tcattttgat
    20341 attgttattc ctggaaaaag tttgatcgaa ttatctcgct cattaacaaa tgaagaagaa
    20401 atcgtcgaaa tcagcattat ggaaaaccaa gtgttgttca aaacagaaac gatgtatttc
    20461 tattcccgtt tgctagaagg aaactatcca gataccaatc gtttgattcc ttcaagtttt
    20521 aatacagagg ttgaattttc tgttcctagc tttttagcgg cgatcgaacg ggcttcttta
    20581 ctttctcatg aaggccgtaa caacatcgtt cgtttatcta ttcgtccaga tgcggttgtt
    20641 ttatacggaa attcgccaga aatcgggaaa gtagaagaaa gcttgagtta tacagcaagc
    20701 agtggcgatc cattagatat ttctttcaat ccggattata tgaaagcagc gttgcgtgca
    20761 tttggagata tgagcatcaa agtgaaattt atctctgcta ttcgtccatt tacattggaa
    20821 ccaacggaag atggcgttca atttattcag ctgattactc ctgtacgtac aaattaacaa
    20881 tgattttcaa tgttcttgaa aatttaattg aaaagaaata gaaaaaataa aattttaaac
    20941 agaaggccct aaaatctctt ttaaggcttt ctgtttattt ttgtttaaat cacctttttt
    21001 agattaaatc gtcttatatg gaaaaatata tggataaatt tgttttattg cgaaaaaaaa
    21061 ggtataatag agtatacttt taataatgaa aatgagggat gggcattgaa acaacaagtc
    21121 attctaaata cggaattcat gacgttgggc caaatgttga aagaagtcac agttatcggt
    21181 agtggcggac aagcaaaatg gtatttggca gaaaacactg tgttagtcga tggcgaacca
    21241 gaaaatcgtc gtggacgcaa actttatccc ggcatgatgg ttgaagttcc agaagtagga
    21301 acttttttta tggtaaaaaa aggaaacgac gataatgagg ctgaataagc tgtatttaaa
    21361 aaattatcga aattacgaag agctgaacat cgaattttcc aagaacctcg tcatcttttt
    21421 aggagaaaat gcgcaaggaa aaacgaatct tttggaaagt atctacgtat tagctatgac
    21481 gcgaagtcat cggacaagta gtgagcagga attgattggc tggactgacg atcaggcgat
    21541 gattcaagga gagatcacaa aaggttcatc cactcttcca ttagaaatct tattatctaa
    21601 aaaaggccga aaaaccaaga tcaaccatat cgaacagaaa aagttaagta cttacgtggg
    21661 acaaatgaat gtcattttat ttgcaccaga agatctttct ttagtaaaag gcagcccgca
    21721 gaccaggcgg aagtttttag atatggaatt aggccagatc aatccaatct atctttatga
    21781 tcttgtccaa taccaagcaa ttttgaaaca aagaaaccag tacttgaagc aattgaatga
    21841 aaaaaaacaa actgatttgc tttatttgga tattttgtcc gaacaactag cagcgtttgg
    21901 cagcaaagta ttgaaagcaa gagcacagtt cgtcaagcga ttggagtttt gggctaattc
    21961 tttgcatcag caaatcaccc atcaaaaaga gcagctggaa atcgagtatc tcaccgcagt
    22021 cgattcttta gaaacacata cgcaagagca aatccaagaa caatttctcg cacttttgaa
    22081 ccaaaataaa aagaaagacc tttttcgggg aacaacgaca gttggtcctc atcgtgacga
    22141 tctttccttt tttattaatc agaaaaatgt gcagacttat ggatcgcaag gacagcaaag
    22201 aacaactgca ctaagtgtca aattagcaga aatcgatttg attaaagaag agacagggga
    22261 atatccaatc cttttgttag atgatgtgat gagcgagctg gatgataatc gtcaactcca
    22321 tctgctagaa acaatcgaag gaaaagttca aacgttctta acaacaacga cacttgacca
    22381 tgtaaaaaat aaaatgactg ttgaacctga gattttttat gttcaacaag ggaaactaaa
    22441 aggagaagaa actgaatgac agaagaaaga agtttagtag aacgcgctaa agagtatgat
    22501 gccagtcaga ttcaagtact tgaaggactt gaagccgttc gtaaacgacc tggcatgtat
    22561 atcggttcga ctagttctga gggtctgcat caccttgttt gggaaattgt cgataattcg
    22621 atcgatgaag tattagcagg ttttgcaacg aaaatccatg tgattattga aaaagacaac
    22681 agtatcaccg ttattgacga cggtcggggg atacctgtag atatccaggc aaaaactgga
    22741 cgtcctgcag ttgaaacggt ctttactgtt ttacatgctg gaggaaaatt cggcggtggt
    22801 gggtacaaag tttctggtgg acttcacgga gtaggatctt ctgttgttaa cgcgctttct
    22861 acacagcttg atgtcaaagt atacaaagaa ggaaatgtgt actatcaaga atatcgtcgt
    22921 ggagctgtag tggacgactt aaagattatc gaacaaacgg atcgccatgg aacaacggtt
    22981 cactttacgc cagaccctga aatttttaca gagacaactg agtttgattt ttcaaaattg
    23041 gctacccgga tccgtgaact tgctttcttg aaccgcggga tgcgtatatc gattgaagac
    23101 aaacgagaag aagaaccagt catcaatgaa taccattatg acggcgggat taaaagttat
    23161 gtcgaatact tgaatgcaaa caaaaccgtg atttttccag aacctgtata tttggaaggt
    23221 gaacagcaag atatcgcagt tgaagtctct atgcaatata cagacggcta ccattccaat
    23281 atcatgagtt ttgccaacaa tatccatacg tatgaaggcg gaacacatga atcaggattc
    23341 aagactgctt taactcgtgt gataaatgat tatgcccgaa aacaaaagct gatgaaagaa
    23401 aatgacgaca acttgaccgg tgaagacgtg cgagaaggat tgacagctgt tatttctatc
    23461 aagcatcctg accctcaatt cgaaggacaa acaaaaacaa aattgggcaa ttccgaagta
    23521 cggacagtca ctgatcggtt atttagcgaa catttcatga aattcttgct ggaaaaccca
    23581 agtgtgggcc gtcaaattgt tgaaaaagga ttactagctt ccagagctcg tctagcagcg
    23641 aaacgtgcgc gtgaagtaac gagacgtaaa ggtgctttag agattagtaa tctgccagga
    23701 aaattagcgg actgctctag caacgatcct gaaaaatgcg aattgttcat cgtcgaagga
    23761 gattcggccg gcggatcagc taagcaaggt cgtaatcgag agtttcaagc catcttgcct
    23821 attcgtggga aaatcttgaa tgttgaaaaa gcaagcatgg acaagatctt ggcaaatgaa
    23881 gagatccggt ctttatttac tgctatgggt acagggtttg gagaagattt tgatgtatcg
    23941 aaagctcgct accacaaatt agttatcatg actgatgccg atgtcgacgg cgcgcatatc
    24001 cgtacattgc tgctgactct tttttatcgt tacatgcgtc ctattgttga agctggatac
    24061 gtctatattg ctcagccacc tttatacggg gtaaaacaag ggaagaatat tacgtatgta
    24121 caaccaggaa aaaatgcaga agaagagttg aaacaagtcg ttgcttcact tcctgcctca
    24181 ccaaaaccaa gcgttcagcg ttataaagga cttggagaaa tggatgatca tcaactatgg
    24241 gaaacaacta tggacccaag caatcggatg atggcccgcg tcagtgtgga cgatgctatt
    24301 gcagcagatc agatatttga aatgttgatg ggggatcgag tagaaccccg tcgtgcattc
    24361 atcgaggaaa atgcacacta tgtgaagaac ttagatattt aatcatgaag gaggaaaaag
    24421 aatgagtgaa gaaatcagag aaaacatcca tgatgtcaat ctaaccagcg aaatgaaaga
    24481 ctccttcatc gattatgcga tgagtgttat tgtcgcacgt gcacttcctg atgtcagaga
    24541 tggtctgaaa cccgttcatc gccgtatttt atacggcatg aacgaattag gtgtaacacc
    24601 ggataaagcc cataaaaaat ctgccagaat cgtcggagat gtcatgggta aataccatcc
    24661 tcatggagac tatgcgatct atgagtcaat ggtacggatg gcacagccat tcagctaccg
    24721 ttatatgcta gtggatggtc atggaaactt tggttctgtt gacggtgacg gtgccgccgc
    24781 tatgcgttat accgaagcac ggatgagcaa aatcgctaca gaaatgctgc gtgatatcaa
    24841 taagaacact gttgatttcc aaagcaacta tgatgataca gaaaaagaac cagttgtact
    24901 acctgctcgc ttcccgaatc ttttagtgaa cggaacaacg gggatcgccg taggtatggc
    24961 cacgaatatc ccacctcata acttgtctga ggtagtagcg gctatcgatt tgctgatgga
    25021 taatcctgat gtgacgacca atgaattgat ggaagtatta cctggaccag attttccaac
    25081 aggtggtttg gttatgggaa aatcaggaat ccgaagagcg tatgaaacag gtaagggttc
    25141 tattaccgta cgtgcaaaag ttgagattac tgagatgcca aatggtaaag aacggatcat
    25201 cgtgacagaa ttgccttata tggtcaataa agcaaaattg atcgaacgga tttctgaact
    25261 gcacagagac aagcgtatcg aagggatcac agatttgcgg gacgaatctt cccgtgaagg
    25321 tatgcggatc gtcattgaca tccgtcgtga cgccagcgca tctgttatct tgaataactt
    25381 atataaattg acatccttgc aaaattcatt tggattcaat atgttggcga tcgaaaaagg
    25441 tgtgccgaaa gttttgagct tgaaacaaat tcttgaaaac tatatcgaac atcagcgcga
    25501 agtcatcaca agacggacag tctttgaaaa agaaaaagca gaagcaaggg cacacatttt
    25561 agaaggtttg cgtattgctt tggatcatat cgatgaaatc attgcgatta tccgcgggtc
    25621 taaatcagat gacgaagcaa aagcgacgat gatcgaacgg ttcgatttat ccgatcgcca
    25681 gtctcaagct attttagata tgcgtttacg ccgattgacc ggtttggaac gggaaaaaat
    25741 cgaaaatgaa taccaagaac tcttaaaact gattgaagat ttaactgaca ttctggcaag
    25801 accagaacgt gttacagaaa tcatcaagaa tgaattagca gacttgaatc aacgatttgg
    25861 tgataaacga cgcacagaat tactagtcgg tgaggtctta agtctggaag atgaagattt
    25921 aatcgaagaa gaagaaatcg ttattacatt gacaaacaat ggttacatca aacgtttggc
    25981 aaataatgaa ttcagagctc aacgaagggg tggacgtggt gtccaaggaa tgggtatcca
    26041 caatgacgac ttcgtcaaaa atctggtttc ttgttctacc catgatacat tgttattctt
    26101 tacgaataac ggaaaagtgt atcgggcaaa aggatacgaa attccagaat acgggcgcac
    26161 agccaaagga ataccaatta tcaatttact aggtatcgat tcgagtgaaa gcatccaggc
    26221 aatcattgcg gtgacgggag aagcagaaga aggccactat ctcttcttta cgacgcgtca
    26281 aggtacagta aaacgtactt ctgtcactgc ttttgctaac atccgaagta atggtctgat
    26341 cgcaattggt ttgaaagaag acgatgagct cgtcaatgtg ctactgacag atggtcaatc
    26401 taatatcatt attggaacac ataacggcta ctctgtcact ttcaaagaag aagcagtccg
    26461 cgatatggga cgtacagctt ccggggttag aggaatacgc ctgcgtgagg aagattatgt
    26521 cgttggggca gccttaatga aggaagatca agaagtatta gtgatcacag aaaaaggtta
    26581 cggaaaacgg acaaaagtat cggaatatcc agtgaaaggc cgcggaggta aagggatcaa
    26641 aacggcgaac atcactgaaa aaaatggtcc actagctgga ttgaccactg tttctggaga
    26701 tgaagacatc atgctgatta cagataaagg tgtcattatc cgtttcaacg tatcgactgt
    26761 ttctcaaact ggacgttcaa cattaggcgt acgtttgatg aagatggaag ctgatacgaa
    26821 agttgtcacg atggcagcag tcgaaccaga agctgcagaa caaacagttg aagaacaagg
    26881 atcagaagaa tagccatcaa gactaattgt gtaagctagc aagaatgacc gattaaaaaa
    26941 tctggttatt cctgctggct tttttgatta gttgaatttc tcttaaaata ttcgaaactg
    27001 ttcattctgt attgcttttg accaaaatag agtgtataat cagagcttgt gagtagtcta
    27061 attaattaga taactctcct tgctcttagg aacctaagag ccgaaagtcc acagggaggt
    27121 gaatatcaat ggaaaacacg aaatatgaaa tcatgtacat tattcgtcca aacattgatg
    27181 aagaagcaaa aactgcttta atcgaacgtt tcgatgcaat cttgaaagat aacggagcag
    27241 aagttatcga atcaaaagat tgggaaaaac gccgtttcgc ttatgaaatg aacggttacc
    27301 gtgaaggtat ctatcacatc gttaaagtat cttctccatc atcagcaaat gctgtcaatg
    27361 aatttgaccg tcttgctaaa atcaacgacg atatcattcg tcacatgatt gttaaagaag
    27421 aagcttaatt gttgtttcat gtgaaacaat agaaaacgat gagaggagat gactattttg
    27481 attaataatg ttgtattagt tggacgtctg acgaaagatc cagatttgcg ttacacagca
    27541 agtggtacgg cagtcgcaac atttactttg gctgtgaatc gtaattttac aaaccaaagc
    27601 ggcaatcgcg aggctgattt tatcaactgt gtgatttggc gcaaatcagc agaaacttta
    27661 gcaaactatg ctcgtaaagg aacactttta ggtgttactg gacgtatcca aactcgttct
    27721 tatgataatc agcaaggaca acgtgtatac gtgacagaag tagtagctga caacttccaa
    27781 ttgctggaaa gtcgttctgc atctgaaaat cgccaacaaa gcggcggatt ccaaagttct
    27841 ggtcaatcag ctggcggatt tggcggaaac aataactcta atcaaacatc tcaatcatcc
    27901 aacggtatgc ctgatttcga ccgtgatact tctgacccat tcggctcaag ttcaacgatc
    27961 gacatttcag acgatgattt accattctaa acgaatttga taggagggaa atagaatggc
    28021 acaacaaaga agaggcggac gtaaacgtcg taaagtagac tacattgctg ctaaccatat
    28081 tgaatatatc gattataaag atatcgaatt actaaaaaga tttatttcag aacgcggtaa
    28141 aatcttgcca cgtcgtgtaa ctggtacagg cgctaaaaac caacgtaaaa ttactgttgc
    28201 aatcaaacgc gctcgtatca tgggcttgct acctttcgtt agcgaagact aataaatcct
    28261 aggaattgaa tgactgatcc ttttgatcag ctattcaatt cctttttttc tgtaaaaata
    28321 acctctattc gtttagtcgc tcgaatgacg aaagttatgg taaaatcaaa ttagtcatat
    28381 atgggaggaa aattatggaa aataaaaaca atcatttatc cccgaaacct ctcttcctta
    28441 tcctgtttat attaatcgaa gtattggtag tcttaatttt accatttcgt tttgttagcg
    28501 cttcggtcat tctattgatg aatttatggg gtgttcgcta ttggttgaaa atgaaacgtt
    28561 ggcttatttt aaataaacgt gaaaaaatcc agcaggcttc gactgtagct gaaaccaatc
    28621 tagcttatgt ctcagaagtc atgcctgtag gagtgattgc ttatcagcca tcaagccaaa
    28681 aaatcgaatg gctcaatcca ttagcattga aaatcaaaga tcaaagtgga ttaacagagg
    28741 aagaattgct agatactttt tttactgcaa aagaaaaaaa gaaaaaccaa gtctatctag
    28801 cagataaaac atttcagttt gatatggata cagtaaaggg tgttgtttat tttaatgata
    28861 ttacccaaaa ccagttgtta aaactccatc agacgaacag tcagccggtg attggtattt
    28921 tatctattga taactatgca gatgccattg ataaattgga tgacaaagag atttcttatt
    28981 tgaactcttt cgtcactaca ctagtttctg actggatgaa tgaataccat gtctttttca
    29041 aaagaatcaa cgcagaacgg tttttcttcg tagcacagat gatcgatctg aaaaagatga
    29101 tggataaaaa atttgatttg ctggatcgct ttcgagcaga agctgaaaaa cagagctcgc
    29161 ctatcaccct tagtatgggg attgcttatg gctcaagaac cctcgatgaa atcggtggag
    29221 aagctcagaa taatttagat gttgctttag tccgtggagg cgaccaagtt gtcgtgaaag
    29281 aggtaaaaga aggagcaaaa cctgtttatt atggggggaa atctgctaag aatgtcaaac
    29341 gcacgcgtgt tcgttctcga gcgatgagta ccgctttgcg tcggattttt gatgaaacag
    29401 gcgatgtgtt tatcatgggg cacaagtttc cggatatgga tgctttaggc tctgcttttg
    29461 gtgtcagttg tctggcacgc ttcaaccaga aaaaagctta catcgttatc aacgagaacg
    29521 agatcattcc agatgtagaa cggtgtcttg aagaaatcca taagcatcct gaattagaaa
    29581 tgcaactaat ctctccagaa cgtgccatag agctgaaaaa agaagaggac ctcctcgtga
    29641 tggtggatta ccataaacct tctctatcga tctctcaggg cctatatgag caatttgata
    29701 agattgtgat cattgatcac catcgtcgtg gggaagagtt tccaagtaaa cctctgctga
    29761 cttatatcga atcttcagct tcttcagctt cagagctagt ttctgagctg atccaatacc
    29821 aaagcagcaa aacaaatcgc ttagatcgtt ttgaggccac attattgctt gcagggatgg
    29881 ttgtagatac aaatagtttc aatgtccgta caactgcacg aacttttgac gttgccagct
    29941 atttaaggtc ttgtggagca gacgcatcct tagtacaata tttattgagc tcggatttag
    30001 cgacatactt ggagatcagc aatttgattg ctggaagcga ctatgtgact tctgatattg
    30061 ttgtggcggc agggacagac gaaaaagagt ataatagtgt tatagcagca aaaacagcag
    30121 atacattgct ttcgatgatc aatatcaatg cagctttcgt cattacaaag cggacagacg
    30181 gcttgattgg gatcagtgcc agaagtaccg gcacgatcaa cgtccaaatc atcatggaat
    30241 ccttaggtgg cggaggacac ttcacaaacg cagctactca actggaaaat acgacagttg
    30301 aggaaacaaa acagaagcta tttgctgcaa tcaaagaaaa tatgaatcaa atatatgata
    30361 aggagtaatc caaatgaaag taattttttt acaagatgta aaaggaaaag gtaaaaaagg
    30421 ggacatcaaa gaagttccag caggttatgc acaaaattat ctaatcaaaa ataacttggc
    30481 aaaagaagca acgaaaagca gtatcagtca gttagcagga caaaagaaag cacaagaaaa
    30541 acacgaagct gaaatcttgg aagaagctaa aaagttaaaa gaattcttgg aaaaagaaga
    30601 tactgtagtc gaattgaagg cgaaagcagg ggaagacagc cgtttgtttg gttcgatccc
    30661 ttcaaaacaa attgctgaag ggttaaacaa acaatacaaa atcaaattag ataaacgaaa
    30721 aatcgaatta gaaaatccga tccgttcact aggctacaca aacgtacctg ttaagcttca
    30781 tcatgaggtg acggctacga tcaaagttca tgtcgtacaa gaataacaaa tcttgatagc
    30841 gatgttcagc tggtaagtat aaccagaagg aaaaaagaca aaccgaaatt tatctgagaa
    30901 aacagctgca gcaatgaaag caaaagctgc aaatcgattt cagattgatt tcggtttctt
    30961 ttttgggaac agcaaaatag cataaagaaa acgagtataa taaaagagaa ctattttttt
    31021 attacacttt cggtacgaat gatgactttt ctctcatttt cttgtaaaat gaagcaattg
    31081 aagacaagga gcgatacgta tgaatgaagt gtggcaggat cgaatcccac cgcaaaatat
    31141 tgaagctgaa caagcggttt taggctctgt ttttcttgac gcagaaacga tcattgatgc
    31201 catggagtac atagagccaa aagactttta tcgtcgtggc catcaaatta tttttgagac
    31261 aatgatcgag ttaaatgatc gtaatgaagc gattgacgtg gttactgtca aagaccggct
    31321 ggaacaagcc aatttgttag aagatgccgg tggtttaagt tatctctcag acttggcatt
    31381 agcagttccg acagcagcaa atatcgtcta ctatgcgaaa atcgttgaag aaaaatcatt
    31441 gctgcgtaca ttgatccaga cagcaacagg aatcgttacg aaaggattcg agcaaggaga
    31501 agaagttcaa acaattttag atgatgccga acgcagtatc ttggaggttt cggaaaaaag
    31561 aaatcgaagc ggctttttat ctattgctga agtactgaac tccacgattg aaaatatcga
    31621 tcgactagct caaaacaatg aagaaatcac aggtctacca actggctatc aaggtctgga
    31681 taaaatgaca gcaggtttcc agcccgaaga actaatcatt cttgctgcac gtccagcggt
    31741 aggtaaaaca gcgtttgcat tgaatattgc tcaaaatgta ggaacaaaaa cagatcgttc
    31801 tgttgcgata tttagtttgg aaatgggggc agaatctctt gtaaatcgga tgctttgtgc
    31861 agaaggttcg attgaggcca gccatttacg tacaggtcag ctttcggaag aagaatggtc
    31921 gaatctgatc gttgcgatgg ggagtctttc tcgagcaaat atttttatcg atgatacacc
    31981 agggatcaaa atctctgaaa tccgtgcgaa atgtcggaaa ctagcgcaag aaaaaggcaa
    32041 tctaggcttg atattgatcg attatttgca gttgattgaa ggtaacggta aagagaaccg
    32101 tcaacaagaa gtatcagata tctctcgcca actgaaaaaa ctggcgaaag agctgaaagt
    32161 acctgtcatt gctctttcac agttatctcg tggagtagaa cagcgacaag acaaacgacc
    32221 agtgctaagt gatattcgtg aatccggatc aattgaacaa gatgcggaca tcgtagcctt
    32281 cttgtatcga gatgattatt atgaaagaga aggcggagat gacgatgatg gaaacgagcc
    32341 aaaaaatgac aacgtcatcg aagtcatcat cgagaagaac cgaagcggtg cacgaggaac
    32401 agttgaacta ctgtttatca aagaatacaa taagttttcg tcgctttcgc caagagaaga
    32461 attttaaaga agaggttgtg agccttgagc aatcccgaga gctctcgtaa gaagatgcaa
    32521 ggagtaaccg caggaacgac tagagtactt aatttaaaca gatctccaaa gggattgtga
    32581 caaaagtctt gtcacagtcc ctttttccga ataaacggtg ttcaatcagc tgacccttgg
    32641 tattagctca gcaaacgtca aaatatgagg aactattttg acgtttgttt ctctaatact
    32701 caggtcaaaa cgctgatctt acgacctctt ttccttaaac ggtgttctcc tgccaactcc
    32761 tcggtcacaa gtcacaatat catcaaacat gagaagcagt tttttgaaat tgctccttgt
    32821 gactcagagt taaacggcag gctcacaacc tctttcttaa acggtgttca aaagcttgca
    32881 tctgcggtaa tacgcccaat caaacgaaaa atatgagaag ctatttttgt ttggctgttc
    32941 ttattacttg atgcaggaca gctttttcac aacctctgat tcacggtgtt ccaaaagtag
    33001 cttcttcgaa aaataagtcg aaatttcaca aaaatttgag aagcaatttt cgtacattcc
    33061 ttcttatttc ttgaagctga ccacttctgt tacaacctct tttttaataa ccattctaaa
    33121 aagataaagt tcgtttttta agcgttttta taaaataaaa ataaaaatca ttcgatttta
    33181 tttgaaatat gtatctatta ttgatacaat ggttcaggat taaataatat agaacgaggt
    33241 gttcacatgt catctgtagt agtagtaggt acgcaatggg gcgatgaagg gaaaggaaaa
    33301 atcacagact ttctcagtga aaatgctgaa gtgattgcac ggtaccaagg tggcgacaat
    33361 gcagggcaca caattaagtt taacggtgtg acttataaac tgcatttgat tccttctggg
    33421 attttttata aagacaagat cagtgtgatc ggaaacggcg ttgtagtcaa tcctaaatca
    33481 ttggttaaag aattagctta tttacatgaa aaaggtgtag aaacaagtaa tttgcgtatt
    33541 tctgaccgcg cgcacgtaat cttgccttat catatcaaat tggaccaatt acaagaagat
    33601 gctaagggcg aaaataagat tggtacaacg attaaaggaa tcggacctgc ctatatggat
    33661 aaagcagctc gtgtaggtat ccgtattgca gacttattag ataaagaaat ttttgaagaa
    33721 cgtcttcgtt tgaatctaga tgacaaaaac cgtcaatttg taaaaatgtt tgattcagaa
    33781 ccacttgatt ttgacgatat ttttgaagaa tattatgaat acggacaaca aatcaaacaa
    33841 tacgtcacag atacttccgt tatcttgaat gatgctttgg atgcaggcaa acgcgtgttg
    33901 tttgaaggcg cacaaggtgt aatgctggat atcgaccagg gaacttatcc ttttgttact
    33961 tcttctaacc cagtagccgg tggggtaaca atcggaagcg gtgtagggcc ttcaaaaatc
    34021 aataaagttg tcggcgtctg caaagcctat acgtcacgtg tcggtgatgg accatttcca
    34081 actgaattat ttgatgaaac aggagaacaa atccgcgaag taggacgaga atacggtacg
    34141 acaactggtc gtccgcgtcg tgtaggctgg tttgattctg tagttatgcg ccattctaaa
    34201 cgagtttcag gtattaccaa cctatcttta aactcgatcg atgtattaag tggattggaa
    34261 acagtaaaaa tttgtacggc ttatgaatta gatggcgaac taatctacca ctatccagca
    34321 agcttgaaag agttgaaccg ctgcaaacca atctatgaag aattgccagg ctggtcagaa
    34381 gacattacag gatgcaaaac acttgcagaa ctgccagaaa acgcacgtaa ctatgtacgt
    34441 cgtatctcag agcttgttgg tgtacgtatc tcaacatttt ctgtcggacc tgatagaaca
    34501 caaacaaaca tcttagaaag cgtctgggcg caaatctaag gataaaaacg acgactgaat
    34561 caggacgttc ttaccagagc gagtcgaagt gtttatctat acgataataa taacttgaac
    34621 actgtttatt cagaataagg gactgtgaca aaaaccgtgt cacagtccct ttttccgaa
//
LOCUS       DAFEEZ010000026        34520 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000026
VERSION     DAFEEZ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.026"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(133..306)
                     /locus_tag="LP245_001326"
     CDS             complement(133..306)
                     /locus_tag="LP245_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1519256.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            754..3116
                     /locus_tag="LP245_001327"
                     /pseudo
     CDS             754..3116
                     /locus_tag="LP245_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            3484..4407
                     /gene="truB"
                     /locus_tag="LP245_001328"
     CDS             3484..4407
                     /gene="truB"
                     /locus_tag="LP245_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBL1519257.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            4411..5352
                     /gene="ribF"
                     /locus_tag="LP245_001329"
     CDS             4411..5352
                     /gene="ribF"
                     /locus_tag="LP245_001329"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBL1519258.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            5704..6489
                     /locus_tag="LP245_001330"
     CDS             5704..6489
                     /locus_tag="LP245_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1519259.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            6502..7353
                     /locus_tag="LP245_001331"
     CDS             6502..7353
                     /locus_tag="LP245_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBL1519260.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(7477..7929)
                     /locus_tag="LP245_001332"
     CDS             complement(7477..7929)
                     /locus_tag="LP245_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1519261.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(8394..8762)
                     /locus_tag="LP245_001333"
     CDS             complement(8394..8762)
                     /locus_tag="LP245_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBL1519262.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            8912..9394
                     /locus_tag="LP245_001334"
     CDS             8912..9394
                     /locus_tag="LP245_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBL1519263.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            9431..10441
                     /locus_tag="LP245_001335"
     CDS             9431..10441
                     /locus_tag="LP245_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBL1519264.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(10556..11269)
                     /locus_tag="LP245_001336"
     CDS             complement(10556..11269)
                     /locus_tag="LP245_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519265.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(11459..12049)
                     /locus_tag="LP245_001337"
     CDS             complement(11459..12049)
                     /locus_tag="LP245_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBL1519266.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            12533..12760
                     /locus_tag="LP245_001338"
     CDS             12533..12760
                     /locus_tag="LP245_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBL1519267.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            12776..13942
                     /locus_tag="LP245_001339"
     CDS             12776..13942
                     /locus_tag="LP245_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBL1519268.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            14176..15219
                     /gene="hrcA"
                     /locus_tag="LP245_001340"
     CDS             14176..15219
                     /gene="hrcA"
                     /locus_tag="LP245_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBL1519269.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            15313..15876
                     /gene="grpE"
                     /locus_tag="LP245_001341"
     CDS             15313..15876
                     /gene="grpE"
                     /locus_tag="LP245_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBL1519270.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            15927..17756
                     /gene="dnaK"
                     /locus_tag="LP245_001342"
     CDS             15927..17756
                     /gene="dnaK"
                     /locus_tag="LP245_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBL1519271.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            17907..19073
                     /gene="dnaJ"
                     /locus_tag="LP245_001343"
     CDS             17907..19073
                     /gene="dnaJ"
                     /locus_tag="LP245_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBL1519272.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(19155..19820)
                     /locus_tag="LP245_001344"
     CDS             complement(19155..19820)
                     /locus_tag="LP245_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1519273.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            19796..19969
                     /locus_tag="LP245_001345"
     CDS             19796..19969
                     /locus_tag="LP245_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519274.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(20014..20751)
                     /locus_tag="LP245_001346"
     CDS             complement(20014..20751)
                     /locus_tag="LP245_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL1519275.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(20753..22255)
                     /locus_tag="LP245_001347"
     CDS             complement(20753..22255)
                     /locus_tag="LP245_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBL1519276.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            22514..24508
                     /gene="uvrB"
                     /locus_tag="LP245_001348"
     CDS             22514..24508
                     /gene="uvrB"
                     /locus_tag="LP245_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBL1519277.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKEELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            24518..27334
                     /gene="uvrA"
                     /locus_tag="LP245_001349"
     CDS             24518..27334
                     /gene="uvrA"
                     /locus_tag="LP245_001349"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBL1519278.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            27597..28862
                     /locus_tag="LP245_001350"
     CDS             27597..28862
                     /locus_tag="LP245_001350"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBL1519279.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            28866..29597
                     /locus_tag="LP245_001351"
     CDS             28866..29597
                     /locus_tag="LP245_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBL1519280.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            29732..30616
                     /gene="rapZ"
                     /locus_tag="LP245_001352"
     CDS             29732..30616
                     /gene="rapZ"
                     /locus_tag="LP245_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBL1519281.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            30613..31611
                     /locus_tag="LP245_001353"
     CDS             30613..31611
                     /locus_tag="LP245_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBL1519282.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            31645..32580
                     /gene="whiA"
                     /locus_tag="LP245_001354"
     CDS             31645..32580
                     /gene="whiA"
                     /locus_tag="LP245_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBL1519283.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            33123..33773
                     /locus_tag="LP245_001355"
     CDS             33123..33773
                     /locus_tag="LP245_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519284.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            33960..>34520
                     /locus_tag="LP245_001356"
     CDS             33960..>34520
                     /locus_tag="LP245_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HBL1519285.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT        11452 a         5832 c         7323 g         9913 t
ORIGIN      
        1 aaatcagggg ttgcgggatt tttttgtttt cattaagacg tattacctaa gagttccatg
       61 actttagtct tgcggcgtgt cagctaacca aaaaagagaa aaagaaaagt aaaaaattcg
      121 actttctttt ttctagtagt atataaattt ttgcatatag ataaagatca agataccgat
      181 aacggaagct agattgtaat ctattttagt gacagtcagg tatagccaag taactagaag
      241 atcagtggaa cctgcaccat aaaagtttga gtttgtcggt ccgttgacag ttaaaagaaa
      301 aatcacgttg aagttattga tatttccgat tacgccgctt cgatttggtc acgatccaaa
      361 ttttggataa tccctgtaga aattagcata gtagctggga taccaattca catattgaca
      421 aagataacag agacttttac ataaaacgga tcaatcagga aaggaattgc tcgatccagc
      481 cccagttttc cagcaatgtg ttaactggcc cagcgtcatt cagcaaatta tgcatgatga
      541 ggagcgaaat gaactgcgga acagccattg tgataacgac aagttttttg gatcaatgta
      601 aaaaacgtca gcgaaaggaa aaatttcgtg gttttttata cctgttcatt tggctagata
      661 taaaatccaa acaaatgaac agaagtgctt attaggtttc aattgggagt atctgcgcta
      721 gaataagagt aataatgaaa aggagtgtta tgtatggatt attctagtaa agaatacttt
      781 gataaaatga cggcttggtg gcgtgctgct aattatcttt ctgttgggca actttatctt
      841 aaagataacc ccttactgag acgtacactg aaacccgaag atgtcaaaaa acatccaatc
      901 ggtcattggg gaacgattcc tggccaaaat tttatttatg tccatttgaa ccgagtcatc
      961 aataaatatg atttgaacat gttttatatt gaagggccag gacacggcgg acaagtcatg
     1021 gtatcgaatg cttatttaga tggaagttac acagagatct atccagaagt aacggaagat
     1081 gagacaggaa tgcaaaaatt attcaaacga ttttcatttc ctggaggcat tgcttctcat
     1141 gcagcaccag aaacaccagg ttctatccat gaaggcggag agcttggata ctctctttca
     1201 catgcagtcg gagctgtatt agacaatcct gaagtaatct ctgctgtcgt gattggtgat
     1261 ggtgaagcag aaaccggtcc tttagctgga agctggttct caaatgtctt tatcaatcca
     1321 gtgatagatg gagctgtttt accgatcctt catttaaatg gtgcaaaaat agccaaccca
     1381 acgatcttgg cacgtaaatc agatggagaa ttagcaaatt actttaacgg acttggctgg
     1441 gaacctttct ttattgaagg aaatgattca gaaaaattaa atcctgttat ggctgaaaaa
     1501 atggatcaag caatcgagaa aattaaatcc atccaaaaag aagctcgcct gaagacagca
     1561 acagatgtcg tgatgccaaa atggccagta ttgatcgtac gcacaccaaa aggatggacc
     1621 ggtccaaaag aatgggacgg ggaaccaatt gaaggaacct tccgagcaca ccaagtaccg
     1681 attcctgtag atcaagaaca tatggatcat gcagatgctt tactccgttg gctgaaatcc
     1741 tatgaaccag aaaaattatt tgatgcacaa ggacgtattt tagaagaaat cagagaaatc
     1801 gcgcctactg gtgaccaaag aatggcaaaa aatcctatca ccaatggtgg aatcgatcca
     1861 agaccgctta ttatgccaga ttggaaaaaa tatactttgc aatttgaaaa accaggctcc
     1921 gttaaagcag aagatatgac cgaacttggt aaattcgttc gcgagatcat tgagaaaaat
     1981 ccagaaaatt tccgtatatt tggaccagat gaaacaaaat caaaccgatt gaatcaagtt
     2041 ttcaaaacga caaatcgcca atggatggaa aaaatcgaac cagaaaatga tgaatggctt
     2101 tcgccatctg gtcgcgtcat cgacagtcaa ttatcggaac accaagatga agggttctta
     2161 gaagggtacg ttctgactgg acggcatggt tttttgcaag ttacgaatca ttcttgcgag
     2221 tggttgactc tatgttgact cagcacttca aatggatgcg gaaatcacat gacctttctt
     2281 ggcgaaatga ttatccttcg ctaaatctca ttgcaagctc aacagtcttc cagcaagatc
     2341 acaatggata tagccaccaa gatccaggaa tattgacaca tttggcagaa aagaaggcgg
     2401 agttcatccg tgaatatctg cctgcggatg caaatacatt gctcgcagtc atggataaag
     2461 cattccgctc gtcagaaaaa atcaatttga tcatctcttc caaacatccg cgtgctcaat
     2521 tttactcagc agaagaagca gccgtcttag tgaatgaagg cttgaaaatc attgattggg
     2581 cttcgacagc aaaagaggag gaacctgaat tggtcattgc tgctgcagga acggaatcta
     2641 acttagaagc attagcagct gtaactttgc tgctggaaga attcccaaaa ctaaaaattc
     2701 ggttcatcaa tgtcgtagat ttattgaaat tacgtcatcc aagtcaagat ccgcgtgggt
     2761 tgagcgatga agaatttgat caatatttta caaaagacaa accgatctta tttgctttcc
     2821 acggttatga aacattggtc cgcacgattt tctttgatcg tcataaccat catttaatga
     2881 ttcatggcta caaagaaaat ggagatatca cgacaccatt tgacatgcgt gtagtaaatg
     2941 aacttgatcg ttatcatttg gcaaaagacg cagctttaaa aatcaaagga agtcaagcag
     3001 aagattttgc gaaaaaaatg gatcagaaat tacaagaaca tcaaaactat attcgtgaaa
     3061 atggtattga tctgccagaa gtattggatt ggaaatggaa aaatcttgac caataaaatg
     3121 ataaaatcga tcccgcaaaa tagaattttt tacattgatt aagaaactga aaaaataaat
     3181 aaaaaaaacg gaaaaaagac tggaagaatg gccagtcttt tttttcgttt ttgggaagtg
     3241 aaaaccaaac tatttacctg taagccaccc ataaatccaa tcaaatggtg caaagaaaaa
     3301 atcttccatt ctattccctc ctttaaaaaa gcataacatg atttctattt acgtgagcat
     3361 gaattttgtt acgtttttat tgccgaaaaa taaaaaccgt tcattatgat gtcaaattcg
     3421 tcagtaattg atgcaatgtg ttataataat tcagttaaat caaaaatgaa atggagaaaa
     3481 gacatggacg ggttattacc tttatggaaa gaacgcggaa tgacaagtca tgattgcgta
     3541 ttcaaattaa gaaaaatctt acatacgaaa aaaatcggac atgggggtac gcttgaccca
     3601 gacgtagacg gtgtgttgcc catttgtatt ggaaaagcca caaaagttat cgaatatttg
     3661 acagattctg ggaaaatcta tgtaggcgag ataactctag gtttcagtac aacgacggaa
     3721 gatcgatccg gagaacgggt agaaacaaaa ccagtagata tgtctttatc tgaaaaaaaa
     3781 atagatgaag tgatggcttc atttattggt gagatcaccc agataccacc aatgtactca
     3841 gcggtaaaag tcaacggtaa gcggttatat gaatatgccc gcaataatga aacagtggag
     3901 cgtcctgtta gaaaggctca gatttaccgt tttatccgga caagtgaatt gacaagagac
     3961 gaagtgacag gaaccatttc ttggcgcttc gaagtagaat gcgggaaagg aacctatgtc
     4021 cgcacattag ctgtagatac aggcaagaaa cttggttacc ctgcgcacat gtctgatctg
     4081 acccgaacag caagtgccgg tatgtcccag aaggatgctc tgacattaga agaagtagct
     4141 caagctgtga aaaatgggac aatcgatgat tgtttgctgc caatagaaaa aggagtggaa
     4201 cggttcaaac gagtagatat tactgatgaa gtatggcaga aagtaaaaaa cggtatgaga
     4261 cttgattata ctgtatttgc gctcccagaa atgccgtcag aagaaattgc tttgttttat
     4321 aaaggaaaag ttgtcagtat ttatcagcca aacccgaaag aaaaaaacaa attaaaacct
     4381 agtaaagtat tgagaaatga ggaataacga atgaatatca tcaagatcag acatccttac
     4441 caatcagaac aaattccaga agacgatgtc gttttagtgc tgggattttt cgacggcgtg
     4501 catatcggac accagaaagt cataaagaca ggtatggaaa ttgcacaaaa agaaggattg
     4561 aaattagcat tgatgacttt caatcagcat ccatctattg tctttaaaaa gatcgatcct
     4621 agcagcgtga aatatttgac tagccttaag caaaaagaag aaaaaatggc cgctttgggt
     4681 atagattatt tatatgaagt tgattttact tcttcttttg ctcatttagc accgcaggaa
     4741 tttgttgatc aatacatcgt agggttacat gcaaaatatg ctgtttccgg ttttgattat
     4801 acgtatggac caaaagacat tgcagatgtc gctcattttc ctgaatatgc caaaggaaga
     4861 ttcaaaatcg tcacagtttc taaagaagaa gaacaaggtg aaaaaatcag ctctacccgt
     4921 attcgtggat tactagacag cggacaagta aaagaagcag caaaactatt aggttgcaca
     4981 tatgaggtag aaggggtagt tgtccatggc gatgcacgag gcagactact aggattccct
     5041 acagcaaatg tcaaagtaaa gagcacggtt catttgccta aagaaggtgt ttatgtgtcg
     5101 gaaataaaaa ttggggaaac atggtatcca gccatgggtt caattggaca taatgataca
     5161 ttcggtgaag gacgggagct gactgtagag ttgtatattt tggactttaa tcaagatatc
     5221 tatggtgaac atgtcgcggt acgctggaat caatttttaa gagatcaagt gaaattttct
     5281 agtgtagagg aattgattga acaactcaag gaggatgaac aagcaacagc tgaatatttt
     5341 tctcagcaat aaaacattat gcataaaatc tcttgtttat gtataactag caattacaat
     5401 aaaatgggtg ataaataagc ccaggaaagg ggctgtgaca aaagtcttgt cacagccttt
     5461 ttttccaaat aaatggtttt tcagaagtag cttcttcgga aataagccga aatttcttga
     5521 agctgaccac ttctgtcaca acctctttct ttatagaaat aaaaggacac tagcaattca
     5581 tgaaaacgat tgctagagcg tatcatttgc tttagactat atatcttggt gtacactcac
     5641 tttaaggcgg aaataaaagt tatccgtaat aacaggttta ggtatgaaaa aggagtgggt
     5701 actatgtaca aggaattaga aaacaaagtc gcagtagtaa ctggtggctc aaaggggatt
     5761 ggaacagcga ttgctcaacg attcgggaaa gaaaaaatga atgtagttgt caactataac
     5821 tcggataaag aaggagcaga aaaagcagtc aaagcaatcg aagaggcagg cggaaaagca
     5881 gtctctgtac aagcagatgt cagttctgaa gaaggaatac agcgtttact tgatacggct
     5941 ttagaaaatt ttgggacact ggacgtttgg gttaataatg ctgggatgga aaatcagcat
     6001 ccaacccatg aacttagcct tgaagattgg gaaagagtgt taaaagtcaa tttgactggc
     6061 gtttttatcg gaacgaaagc ggctttaaat tactttacag agaataataa aaaaggaaat
     6121 atcatcaata tgtcttctgt tcatgaacag atcccatggc caacgtttgc tcattacgct
     6181 gcttcaaaag gcggggtaaa attatttacc gaaacggtag caatggagta tgcaccgaag
     6241 ggaatcagaa tcaatagtat aggccctggt gctatccgta cacctattaa tgcggcaaaa
     6301 tttgatgatc ctgaacaaaa agaactcttg gaaagtatga tcccactagg acgcgtaggt
     6361 gaaccaaaag aaatagcggc gacagctgca tggttggctt cagacgaatc cagttatgtt
     6421 acaggtatta cactatttgc agatggtggg atgactttat atccttcttt ccaaggtgga
     6481 aaaggataag ggtgaataaa aatgggttta ttgattgcat tgatcccggc agttggctgg
     6541 gggatccagc cactgatttt gaaaaagatt ggtggcagac caacaaatga gatattagga
     6601 actggtattg gagcggtgct tgtcggctta ctcgttcaat tattcgcttc tccagctggt
     6661 atttcagtga ctacattttt gattagttta ctttctggtg cattttgggt tattggacaa
     6721 acaggacagt atacatcttt caacttgatt ggtgtttcta aaacgatgcc aatttcgact
     6781 gcattacagt tagtcggaac ctcgttgatt ggtgtcttcg cttttggaga atggtctgga
     6841 agtatgggga aaatcattgg agcagcagca atcattcttc ttgtatttgg ttctgcttta
     6901 acggcaatca gtgatgatcc tggaaaaaaa ggcggtatca caaaaggaat tagtctatta
     6961 gcatcaacaa gtattggtta ttgggtatac agtgcattgc ctaaactagt tgatgcaagc
     7021 ggactttcca ttttctttcc gcaaatgatc ggtgtctttt taggggcagt gatttatgtg
     7081 attttccgta aaccaaccgc attttctgaa gacaagagtt ggaaagcaac gatcgttgga
     7141 gccatcttta gtgtgtcagc attggcttat attttttcag caaatgaaaa tggggttgct
     7201 actgcatata tcattacaca gctaaacgta gttatctcta cattaggcgg tatgtacatc
     7261 ctgcatgaaa ataagacacc aaaagaaaaa aaattaacga ttatcggatt attgctgatc
     7321 gtagtaggaa gcatggtcac ggtctttatt tgaggataaa gatggtaaaa tttcatttat
     7381 taaaaaaata tttgtttgaa ccaaacagta agtacttata aaaaaatagc gctagaattt
     7441 ccaacatctc tggaatttct agcgcttttt aattgtttaa gatacaaggg aaatatctgt
     7501 ctggatcaat aatttttcat tgatccattg actaaagttt acgacataat tgaagttacc
     7561 accgattagt atctccgcat gattgtcttt ataaagatcg tattgtaaaa gacggtcttt
     7621 tttatttgcg taaacatcgt tatggtactg gactaattgt tctcggaatt gattgattgc
     7681 tgtaaaatca cgatattgaa ggttgaaacg catcgtgatt ggtgcattta gcatgaatcg
     7741 ctgcatttct tttgctgctt cctctgcttg atctccgtat aggaactcaa aaagattacg
     7801 ttcagaaaat ttccattgcc cgccaacctt tgttcctttt agttttcctt catgaagata
     7861 atttctgata gaacgtgtag taacacctaa ttgttcggct aattcattta ctgagtaaaa
     7921 atctttcaat gttcaccctc ctatgtgaat ggttctactg acttagttga tatttgctta
     7981 atcacgaaat gtagaaagaa cgattttaat taaggtcatt gtaaaaatca agtcagaaaa
     8041 ttctaacttt tatttctcta aagaaattcg ttctctccta aagtgatatt atatttaaat
     8101 atacctgaaa ataatgggca gtattatgaa agatcactga tattttctcg tattttttcc
     8161 ttattcaaaa gttttgcagg aaaattgctg aaaaaataat tttactaagt agaaaattca
     8221 aagccattca atcagtgatt tttttcagca caagaaagac tccttataaa aatagcagat
     8281 actttgtcaa ttaagtgttt aaccagggat gataaaaagg ataggattga acaaaacctg
     8341 tataaggtga tgaatagttt cctcgccagt aaaaggttta ttcgtataaa gctttatcgc
     8401 caaaatttat catgaccttt tttatcttca atattaaatg aaatcaattg ttcaatcaat
     8461 tcccagttga ttacactttt ccaaggaact ttgatgacgt tatccgtata tacgtagcct
     8521 gcttcttgga tatttttttc aagggcacga atcgctgctt tttccggtgc gatagaaaaa
     8581 tgatttttag caaaactaaa tgcaataata aaggtaccat ggtcagtaaa cataggttgg
     8641 ttccatttta cagttgtgtc tagctgggga tacgtttctg ttatcttagc aaaaaggtct
     8701 ttgatctttt gttgatgttc tttttctttg atttgattga tgatcggctg aaatttttcc
     8761 attctaaaac gcctccatta agtggtttga tttattttac cagaaaaaca atagttatgt
     8821 ataaaaaacg aacaaaacac aagtaatgtt gtaaccgcta tatttatatg ataagatgtc
     8881 tcaaataata aaatagaaaa gagacataaa aatgattgac ttggcaaaga aattcttaca
     8941 cgaaaatata tattttgagt tgtatcatca tcgagccatt tatacaaatg aagatgcttt
     9001 ggtaataaag aaagaacaag gatttacagg tacagagacc aaaagcttat tcttaaaaga
     9061 taaaaaagat aataactacg tatatctgac ttttactacg aaacaaacgg atttcaaagc
     9121 attagggaag atcgtcggta aaaggctttc tattgtttca tcagaacgca tggaagaaca
     9181 aacgggacaa aagcagggcg ctgtttctcc gtttggttat gaaaaacaga ttccgattat
     9241 tattgatgaa gagctcttat caaatgaaaa acttgttttt gcaccaggta gaccagatca
     9301 aacgatggtc atccaaacgg ttgacttaaa caaaatcatc cagctacttg agatgccgat
     9361 atttttgatg ccggcaaacg aaaaaaacaa ttaaccaagt aaaatagtgc atacttggag
     9421 gtgaagcaac atgataagtt atccattatt agaaagaaat gcaacgattg gggttactgc
     9481 accatcctca ggcgtatcag aggaacacca ttcgttactc gaatcagctt taaagagaat
     9541 ggaagaaaaa tctttccaag tagttactgg aaagacgctt tggacgcaag ataaggaaaa
     9601 atcaggtcca gcaagaaaac gagcagatga attcaatcaa atgatgcaag atgaaaatat
     9661 ccaaatgatc tttccgactt ggggaggaga attattgatt gagattctcg attttgtcga
     9721 ttttgatgct ctacaaccaa aatggatagt aggttattca gatattagta cgttgctact
     9781 tgctgtcaca ttaaaaacag ggatagccac tgcacatgga actaacctta ttgatttaag
     9841 aggagagtac ttggatgaaa cgacagcaat gtgggaaagt gtactgaaaa caagagaagg
     9901 agaatcgatt ctacagcaat cttctgaaaa gtatcaaaaa gtgtggcccc atgagcattc
     9961 atcatcttct gttttccatc tcactgaacc aacaaattgg caatcagtca gcggagatgc
    10021 agtaaggatg aagggacgat tattaggtgg ttgtattgat acgatcaggc atttaatcgg
    10081 tactccttat ggagatgtcc aatcttttaa aagaaagtat aatgatggaa agccgatctt
    10141 gtggtttcta gaaaactgtg agctatcgtc agttgattta agaagatcac ttgttcagat
    10201 gaaactggca ggctggtttg atggcagctc ggggatcatg ttcggtagaa gtgcggcaga
    10261 ggatttgtta gattataaaa tgaaggatgt atacgaagat ctgtcaaagg aattaaaact
    10321 accgatcttg tatgatattg attgtggtca tgtaccgcca caactgacat tgattaatgg
    10381 tgcctatgca gaagtagcgg tagaagatag aaaagcgact gttttgcaaa cgtttattta
    10441 aaaaattttt tcctgccttg gagtctatca aagaccaata aatctaaata gaaaagaaag
    10501 tgaaagaagc tgacaaaatg ctgtcagctt ctttttgtat aacatattag aaagtctaat
    10561 tatctataac tgtcacatcg attaactgtt tcacgtcatt gggatttcct gtaggaatag
    10621 ctactacaga tgcattatca atgatttctt gagttgtttc tctaatgaac gctggataag
    10681 atgtttgatc tgcaggcatt tgccaatgtg aaggaactgg ataactagtg attgtcccgt
    10741 catggttact tgaatacact aaaactccct ggtaactgta tttcccagtg agcataacca
    10801 catctttcgg atagactgca ctccctgcat cataaggggc gataggtgtt cctgcaggat
    10861 aatgaataac atgtaattcg aaatcacccg atgtatctct aaaagtatta cctctaatag
    10921 ctagccaaac acgtgcgtac tcaatttgta gatcagaata tcctgctaac ggatctattg
    10981 actgagaaga ctgtgaggag gttgtgtcta ttgttgaaga agaaatattt gtctcaactg
    11041 tactactaga tgtagaagaa gtattgggct ctgagacttt actgcttgtt gaagatgtat
    11101 tcgtttcagt agaagctgat ttctgagtac ttgatttttc agctgaactg gtttgtctga
    11161 ttgaactttt gtctgtggtc gcagatggat cactattttc tttactagga gacgtacatc
    11221 ctacaaggaa taaagagacc aacaataaaa taaaacctaa ctttttcata taaaatacct
    11281 cattattttt ttaataccag tatagcataa tcctgaattt ttgaatccgt aaaaccttgt
    11341 ctatgaatat aaatagagtg tatcttcttt gataaatgtc agaaaaagtg tgacaaataa
    11401 tcatcagtaa aattacttgt cacactattg ataaggagta tttaattgaa gagaatgatt
    11461 aggagaaagg atctccgtac tttttatagt aatcatagaa tccaagtttg tatagacgaa
    11521 tcgttttttc tcttatttct tctgtttcaa aatggactgc ttgaagaatc aagtctgtga
    11581 attctatagg agctgttcca ttcgcagtaa tcaaattacg atctttcaca gcttgttgtt
    11641 ctataaaatc ttctttattc tgataatttt ccgattctaa ccaaggaaat tgcgcatttc
    11701 cggtgtgttt gtaaccttgc aataatccgc tctgagctaa ataatcaact gccccacaaa
    11761 tagcagctac tggtacgtct gtttttaaca atttatcgat tatttgatat aaatgatgat
    11821 tttttatgtc ccatgaattg ccaccgatca taataaaaag gtcaactttt tcaggtattt
    11881 gttcgattaa gtaatcgatt tttgttttta atcctccaat ggaagtgacc tctgattgga
    11941 tagaagcagt tttgttttgc catttctcat tttggtttag tgtgctagta atataagcac
    12001 cttcccaatc ggcatattcc tctaatagaa acgtaatcgc agttttcatt ttcaagctct
    12061 cctttactat ctataacaag gacaacagtt ttaacctaca gacattcatt aaaattgggt
    12121 agcgacagcg aaaacaacaa ttcttaagtt ttagacagag tatacagata gtcaacttaa
    12181 ttaaatacga actaaataaa aatgacaggt aatcattttt gtttaccagc attataacat
    12241 tttgcataca tggatgacaa aagaaccaat tcccacttgc ttgagtacaa tattaaaaga
    12301 aactggaagg caaaaagtaa ttatagaaac gaaaaataaa tcatatcggg cactcagaca
    12361 tgaaaacaac cctagagata tataactagg taaccagttt aatgaaagaa aaaatcatcc
    12421 aagaagtcga ttcttggatt ttttagtgga tttgttcgcc aaatacgttt agtatgcgta
    12481 tatgagaggt tgtaagcaaa gcgttgtggt ctgagcactt aaggaggaat ctgtgaaaat
    12541 agcttttcat atttttgcag attttgactt aatgccgaag gtcagctttg cgattaccgt
    12601 ttatcgagag gctgtaaaag caccgtgtag ctccgatgac aataagcaag catttttaga
    12661 gctaggtttc cttgattcta aatatgcggc ttatttcaat gagttggtgc ttgaacgcga
    12721 ttttaagaag gtcgaaaaca ggcacgactt ttcgacgtaa ggagaaagaa tttcaatgat
    12781 agaaacaata aatcccgcag aaaacaaggt ttctgcgtac attcatatcc cattttgcga
    12841 gcatatctgc tattactgtg attttaataa agttttttta gaagggcagc cagtagatga
    12901 gtatgtggaa atgctgctga atgaaatgaa aataatgcta gaaagtcatc cgacagcgaa
    12961 tttagaaaca ctttacgtag ggggcgggac accaacttct ttatctgcta aacaacttga
    13021 tcgactgtta tcaggtgcta gagagatcct gccttttcaa aatggtaatg agtttactgt
    13081 agaagcgaat ccaggtgatt tgacccgtga aaaacttcaa gtaatgaaaa actatggcgt
    13141 caatcgttta tccatgggag tgcagacatt tgataatcgc ttattgaaaa aaattggacg
    13201 taaacacacc gcagaagatg tgtatcaaac tatgcaattt ttagaagcag aaaattttac
    13261 caatgtaagc atcgatttga tttatgcatt accgggacaa acactagaag gatatctgga
    13321 tactttggaa aaagctttgg ctttggatct gcctcactat tctttgtact cattgatcct
    13381 cgaaaacaaa acaatgttca tgaactgggt acgacaagga agactcgaac tgcctgatca
    13441 ggaaacggaa accagaatgt ttgaagagac gattgaagca atggaaaagc atggacgtca
    13501 ccaatatgaa ataagtaact ttgggctctc cggacatgaa tctcaacata acctcatgta
    13561 ctggaacaat gaccactatt ttgggtttgg agctggtgct agcggttatc ttggagatat
    13621 tcgttaccgc aacaaaggac caatccaaca ctatttacgc ccattacgag caaatgaacg
    13681 cccggtattg gaagaagaaa aattgacacg aaaaaatcaa atagaagaag aaatgttctt
    13741 aggactaaga aaaaaaacag ggattactaa aaaacatttc tatgatcgct atcaaaaaac
    13801 aattgaatcg gtgtacggtg atgtgctaag ggaattagag caagaagggt tacttgttaa
    13861 tgaagaagac cgtgtttatt tgacaccaag agggaccttt ttggggaaca atgtgtttga
    13921 gcgctttttg tttgaaaaat agtttaaaga atatttgttt tttatctgaa tttaaataaa
    13981 aaaagttcaa aaatacaata aaggactatt gaaacgttga tataactgga tttacatcaa
    14041 ttatttagaa ttagcactct tgtgtttaga gtgctaaaaa atggagtctt tctcttgaca
    14101 ggagaagggc ttcttgctat atttataagt ggattagcac ttagaatata tgagtgctaa
    14161 tgagaggtga ggaagatgtt aacaaagcga caaaacgaca ttttacgtct gatcatccaa
    14221 cactatacga gtagtggcgt gcccgttggt tccaaaacat tgatgtctga gggagtcaag
    14281 gccagctcag caacgattcg caatgatatg aaagcattag aagatgaagg attgctgttg
    14341 aagactcact cttcttctgg gcggattcca tctgctttag gctatcgtta ttacgtggat
    14401 catttgttaa aacctgctcg cgtagcagaa gatgatttgc tgctgattcg tcagtctcta
    14461 ggcagagaat ttcatgaaat caatgagatt attaagcaat ctgctgagat attatctgag
    14521 ctgacaagct atacgacttt ttcattggga cctgaaataa aagaccgccg actgactggc
    14581 tttcgtatcg tacccttgaa taatcgacag attattgcta tcgtcgtaac agatatgggg
    14641 aatgtagaaa gccaagtgtt cactcttccc gaatatatgg gaagtcagga actagaaaaa
    14701 atggtacaga ttgtaaacga ccgtctagtc ggagatcctc tgatgacggt gtaccataaa
    14761 cttcgtacgg agattccgat gattcttcat aaatatttcc aaacgacaga agggatgtct
    14821 cagttatttg acaccgttct tggtcatgtt tttgaagata aggtttatgt cagtggacaa
    14881 atgaatctct tggattatga gccccgtcaa gatcttgatc agttcaaatc gatgttttct
    14941 tttatgaaag actcagacgg acttacacaa atgatcactc cgatggatag caatattcat
    15001 atcaagattg gtgctgaatt aggcaatgat ttattgcaga atatgagtat gattcaagca
    15061 agttacgaga tagatggtca tggaagaggt acaatagcct tgttagggcc tactagtatg
    15121 ccttattctc ggatgttcgg tctagtcgat gtttatcgaa gagaactagc agctaaactt
    15181 gctgattact accgttcgct tgacttgtca aactcgtaat gtgaataacg aagctatttg
    15241 cagctgatcg ttctctcttt cttagtaaga gcaatcaaac agctgactga ataatgaaag
    15301 gaagactgta tcgtgaaaga aaatcaagaa gaactagata aagaaatgac agatgctcag
    15361 ccagaaccgg aaatcgatgt cgaagctgca gaagattcgg gtatttcaga agctgaagcg
    15421 gaagaattcg aaacagcgaa attaaaagct gagttagaag aaatggaaga taaatacttg
    15481 cgggctcgtg ctgaaatcgc aaatatggca aatcgaggaa aaaatgagcg tgagcaatta
    15541 caaaaatacc gttcacaaga tttagccaaa aaattacttc catcaattga caacctggaa
    15601 cgtgcattag ccacagaagt gtcagatgat caaggggcag gtttgaaaaa aggcgtggaa
    15661 atggtcttgg aaagtttgcg taacgcactg gaagaagaag gaattgaaaa aatccctgct
    15721 aaaggagaag cctttgatcc taatcttcat caagcagtac aaactgttcc agcgactgaa
    15781 gatacaccag ccgatacgat tgtagaagta ctacaagaag gctacaaatt acatgatcgc
    15841 gtgttaagac caaccatggt cattgttgca caataattgt gcggatataa aacttacact
    15901 ttcaattaaa gaaggagacg ttaattatga gtaaaattat cggtattgac ttaggtacga
    15961 ctaactctgc agtagcagta ttggaaggaa acgaagcaaa aatcatcgct aacccagaag
    16021 gaaaccgtac aacaccttct gttgtatcat tcaaaaatgg agaaatccaa gtaggggaag
    16081 ttgcaaaacg tcaagctgtg acaaacccaa atacgatttc atcaatcaaa cgccatatcg
    16141 gtgaagcagg ttacaaagta gatgtagaag gtaaatcata tacaccacaa gaaatctcag
    16201 caatgatcct tcaatatatc aaaggattcg cagaagacta tttaggtgaa aaagtcgaaa
    16261 aagcagttat cactgtgcca gcttacttta atgatgcaca acgtcaagca acaaaagatg
    16321 ctggtaagat cgctggtcta gaagtagaac gtatcgtcaa tgaaccaact gcagctgctc
    16381 ttgcctatgg tttagataaa acagatcgcg acgaaaaaat cttagtattc gaccttggtg
    16441 gcggtacttt tgacgtatct atccttgaac taggagacgg tgtctttgat gtattgtcaa
    16501 cagctggcga caaccatcta ggtggggacg actttgataa caaaatcatc gactacatgg
    16561 tagcagaatt caaaaaagaa aacagcattg acttgtctca agacaaaatg gctttacaac
    16621 gcttgaaaga cgctgctgaa aaagcgaaaa aagatttatc tggcgtatca agcacacaaa
    16681 tcagcttgcc atttatcaca gcaggagaat ctggaccatt gcatttggaa atgacattga
    16741 cacgtgcaaa atttgatgaa ttaacagctg acttagtaga acgtacaaaa gtaccagtac
    16801 gtcaagcgct aaaagatgca ggtttatcac aatcagaaat cgacgaagtt attttagtcg
    16861 gtggatctac tcgtatccct gcagttgtag aagcagtacg taaagaaaca ggaaaagaac
    16921 caaacaaatc agttaaccct gatgaagtag ttgctatggg tgctgctatc caaggtggcg
    16981 tgatcactgg tgatgtgaaa gatgttgttt tacttgacgt tacaccattg tcattaggta
    17041 tcgaaacaat gggtggagtg ttcactaaat tgattgaccg caatacaacg attccaacaa
    17101 gtaaatcaca agtattctca actgcggcag ataatcaacc agcagtagac atccatgtat
    17161 tacaaggtga acgcccaatg gctgctgaca acaaaactct aggaagattc caattgacag
    17221 atattccagc agctcctcgt ggtattccac aaatcgaagt aacattcgat attgataaaa
    17281 acgggattgt aaatgtatct gcgaaagatc taggtacaca aaaagaacaa aaaatcacga
    17341 tcaaatcttc ttcaggtcta acagacgaag aaatcgaacg tatggtaaaa gatgcagaag
    17401 caaatgcaga agcagataaa gctcgtaaag aggaagttga cctacgtaat gatgtagatg
    17461 cattgctatt ctctgtggac aaaacattga aagaattaga aggcaaagtg gacgaagaag
    17521 aagtgaaaaa agcagaaaca gctcgcgatg aattgaaagc cgctgttgaa gcaaacaaca
    17581 tcgaagaaat gaaaactaaa cgcgatgcat tgaacgaaat cgttcaaaac ttgactgtta
    17641 aactatacga acaagcggca caacaacaag ctcaagaaaa cccagaagca gctcaaggcg
    17701 gagcagatga tgtcgttgat gctgattttg aagaagtcga tggcgacgat aaataatcag
    17761 ttcactgaat ttcgagagaa ggccaaagtt gctactttgg ctttttcttt tgaaaaatag
    17821 tttgaagtat cggtttttgt ttcaaacaaa atatgatatg ataacaagcg acgtgaaaat
    17881 gatgagaacc aataggagga aagcctatgg caacaaaacg tgattattat gaagtcttag
    17941 ggctctcaaa aggagcatca gaagatgaaa taaagaaagc ttatcgtaag ctttcgaaaa
    18001 aataccatcc tgacatcaat aaagaacctg atgcggaaga aaaattcaaa gaagtatcag
    18061 aagcatatga gattttaagt gacccgcaaa aacgcgctgc atatgaccaa tacgggcatg
    18121 caggcacaga tccaaattac ggtgctggtg gagctggtgg cggatttggt ggattcggcg
    18181 gcttctctgg tggcggcttc ggtggttttg aagatatctt cgactctttc tttggaggag
    18241 gcggtcggtc agtcgatcca aatgcgcctc gtcaaggtgc tgatttgcaa tatacggtcg
    18301 acttgtcttt tgaagaagcg atttttggtg tagaaaaaga aatcaagtat aatcgggaag
    18361 aaatctgtca tacttgtggt gggaacggtg caaaaccagg cacacaacca actacttgtc
    18421 ataaatgtca tggtgcaggt acgattaatg tagaacgcca aacaccactt ggacgagtga
    18481 tgagccgtca aacttgtgat gtttgtcatg ggacagggaa agaaatcaaa gaaccttgtc
    18541 caacctgtca tggctcagga catgagaaga aagcacattc agttaaagtg aatgtaccag
    18601 ctggtgtaga agaaggacaa caaatgcgtt tagctggtca aggagaagct ggagaaaacg
    18661 gcggaccatt tggtgatttg tatgtggtct tccgtgtaga agaaagtgat atctttgatc
    18721 gtgaaggttc tgaaatttac tatgaattgc ctttaagttt tgtacaagca gctttggggg
    18781 atgaagtcca agtaccaact gtccatggag atgtgaaatt gaagatccct gctggaacac
    18841 agacaggtac gaacttccgt ttacgtggaa aaggcgctcc gaagttacgt ggtggtgcaa
    18901 caggcgacca acatgtcaaa gtaaaactga tcacaccgaa aaatctaaat gaacaacaaa
    18961 gagaagcatt acgtgcattc gctgaagctg gcggcatcaa agttgaagaa cagcaagaag
    19021 acggtttctt cgataagttt aaagatgctt ttggcgggaa aaagcggaag tagtttttct
    19081 agtaaaaacg ctaagtcatt aataattaaa aaccagacga acaatcatat gttcgcctgg
    19141 tttttttgta gttgtcatgt ttgtaccaac aaaaaagcca gctttagaat atgataatcg
    19201 tcatagtttc taggggtata accagtgaga gaatggaact tgttcaatcg atattgcaag
    19261 gtgtttttat gaataaataa ttcttctgag caatttttga tgcttccgtt atttttactg
    19321 aagcatgcca aagtcttctt gaacaaatgt acttcttctt ctgtcaggct tttcaaaata
    19381 cgttttacat ataatgttcg ttgatctgac gggattgctg gtaaaacgat cccgaggtct
    19441 aaatcttcaa aaaagcggat ctcgttcaca gattgatgga aagctatcca ttcgcaaact
    19501 tgtttggcat gaaggaaaga ttgcggtgtc tcttgctctg tataacaaag cgacccaatt
    19561 ccaaagttta gctgtaactg atacatttta ttaaactttg tctggatttt atcaagcaat
    19621 gatagcaatg aggctctgga aatccgattg actaggataa tgatttgttg tctatgtaca
    19681 gtgagcaaag cctgtccgta ataagagaag accctttcga gcaactccaa taaaggattg
    19741 atccgttctt gacacaattg ctgattgtca gaaagttgtc ccacaactac ataatatgga
    19801 gaagaaaaat caagctcaat taagtgaggg tggtatcgac tatgtacttg atatcatcaa
    19861 tgaaccgatg gtactttctt atgcgatgga acaggtagag cgattgcttg tttgtgcagg
    19921 aaaacaagcg atgcggctga tacgattagg tgagaaaata agaagataaa aatacacggt
    19981 cccttcatgg cgaccgtgca tttttggttt ttattaaata tttaatactt tattcaagaa
    20041 atcttttgtc cgttcatttt gcggattttc aaagatttgt tgaggcgttc catcttctaa
    20101 aaagtttccg tcgtcaatga acatgacgcg attggccact tctttagcga accccatttc
    20161 gtgcgtaacg ataaccatcg tcataccttg ttctgctaac tttttcatga cgttcaagac
    20221 atcaccgacc atttcaggat cgagtgcaga agtaggctca tcaaaaagca tgatgtcagg
    20281 gttcatcgct agagcacgag caatagccac acgctgtttt tgtccaccag aaagcatttc
    20341 aggatacata tcttttttat cttctagacc aactgtctgc agtaatttga ttgctttttt
    20401 ctctgcttct tctctagatt ctttcttcag gtccatcggt gctaaaatga tgttttccaa
    20461 aatagaaaga tgagggaata ggttaaagtg ttggaatacc attccgatat gttgtctcac
    20521 caagttgata tctgtgcttt tatccatcaa gtgggcgccg tcaataataa tttcaccgtc
    20581 agaaggttct tctaaacgat tcaagcaacg caagaatgta ctttttcctg aacctgaagg
    20641 gccaatgata cagacgacat ctccttcgtt gatggataca ttgatgtcgt ttaatactgt
    20701 gttatcgccg tattttttga ctaaatgctc aactaagatt ttttctgcca tcttacttca
    20761 ccttcttttc taaaactttt gctaattttg tcaatgctgt gatcaaaatc aagtacatga
    20821 tcgcaatgat caagtaaaca tacgtacttt gtgttgtacg tgcaacaatg atcttaccag
    20881 tttgcagcaa ttcgactaca ccgattgcgg aaatgatcgt tgtgtctttt aatgagataa
    20941 cgaactgatt gacgaatgat gggatcatga tgcgtatcgc ttgcggcaaa atgatttttt
    21001 gcattgtccg attataagaa agacctaaac ttctggaagc ttccatttgt ccgacaggaa
    21061 cggcgttgat cccgcctcga acaatctctg cgatataagc acttgcgtta agagtcaagg
    21121 tgataacacc agcaaggaag tcaggaatcg taaatccaac gataccaggc aacccaaaga
    21181 aaataaagaa cgcaagaacc atcattggaa ttcctcggat gatatcgaca taaatactag
    21241 caattgtgcg aagagcgcgt attggtgcta cactgaataa tccaaaaatc acaccgatta
    21301 ctatagccaa agcaaaggag atcaaagtta ggagaattgt tctccaaagt cctttcaaca
    21361 atgcttgata gttgttttgg ataagtccaa gaaatgttga ttcatcagca gtggaagact
    21421 cactggaagt ttctgaacca tccgctacat attctttaat aatcttatcg tattcgcctg
    21481 ttctttttaa ttctttcaat ccttcattga acatattaag aagctcagga ttttgtcctt
    21541 ttttaacggc aaatgcatat tttccgccag attctttttt gatcggtgtt tccaattctt
    21601 gtccttgttt gatcgcataa ccgattaccg gataatcatc catcattgca tcgattgcgc
    21661 caacttttaa cccgtcgtac aattgatcag cagcatcaaa atatttgata gaatagccat
    21721 attcagattc atggtcgctt aaaaattcag cactttcggt accaactttt gctccgactg
    21781 tttttccttt caaatcttca taagacttga tcgaagtatc tccttttttg acagctaatt
    21841 ggatcccgct atcaaagtaa gaatcagaaa aatcatagct tttctttcgt tcatctgtta
    21901 cagtcattcc ggcaatcatt ccgtctgctt gtcctgattc caaagcttgc aaagcagcag
    21961 agaaaccacg gtagtccatt cggatgttaa atccttgcag tttggcgatg ttttccatca
    22021 attttacatc gatgccttcg tactcgccct ttgcgttttg aaattcaaat ggagcaaaag
    22081 cagagtcact ggcaattacg tatacgtctt ttttgggctc tattttttgc attgtctcgc
    22141 ttgtgcttga ctctgccgtt gtagtgttgt cagcttgtgc aacatgacca aacgcaagtg
    22201 tcacaagtcc tgtcattaag aaaacaaatg agtgaaataa atgctttctt ttcataatca
    22261 acctcctaaa tttccaatat tttattatta taggcgaaaa gtgctgaatc agacaagact
    22321 gtaagctcga aaaaatgaaa aaaatgcgag tttctaacat tttatgttat aaaacataac
    22381 atgtataata agataaaaaa gtggcgaaag tatgttcggt gtggtataat tttttagtaa
    22441 ggaatgcctt tgctttcctt ttctttttat tggtcgtaaa atgaaaagga atgaatgaaa
    22501 aggaggacga agaatgattg agagagatac ctcccgacac tttgagcttg tctcgaaata
    22561 ccaaccggct ggtgatcagc ctgaagcgat taaccaatta gtggatggcg tagtcggcgg
    22621 gaaaaaagca caaatcttat taggtgcgac tggaacaggg aaaacatata cgatttccaa
    22681 tcttattgag aaagtgaata aaccaacact gattattgcc cataacaaaa cattggctgg
    22741 tcagctgtac ggggaattca aggaattttt ccctaacaat gctgttgaat attttgtttc
    22801 ttattatgat tattatcagc ctgaagctta tgtgccttca agcgatacgt atatcgaaaa
    22861 agattcaagt gtaaatgatg agatcgacaa attacgacat tcggctacta gttcattatt
    22921 agaaagaaat gatgtgatcg tcattgcatc cgtttcatgt atttttggat taggctcgcc
    22981 ttttgagtac caaaaacaag tagtttcgat tcgacaggga gcagaactag atcgcaatca
    23041 gttgattcgt gacttagtca gtatccaatt cgaaagaaat gatatagatt ttcagcgcgg
    23101 tcgttttcga gtgcgcggtg atgtcgtgga gatttttccg gcttcaagag atgaacgtgc
    23161 cttacgtgtg gagttttttg gagatgaggt cgaacgtatc cgagaagtca atgcactgac
    23221 aggtgaagtt ttaggagaaa cggaacacgt agcaatcttc ccggcgactc actttgtgac
    23281 gaatgatgaa catatggagc atgccgtagc gaatatcaaa gaggaattag aacagcgttt
    23341 aactgtcttg cgaaatgaaa acaaacttct ggaagctcaa cgtttagaac agcgaaccaa
    23401 ttacgatatt gaaatgatgt tagaaatggg ctacacgtcg ggaattgaaa attattctcg
    23461 gcatatggac ggacgtaaag aaggtgaacc gccttatacg ctattggatt tctttcctga
    23521 agattttttg atcgtggcgg acgaatcgca cgtaaccatg cctcaaatca gaggaatgta
    23581 taatggtgac cgagcgagaa aacagatgct agtagattac ggtttccgtt tgccatctgc
    23641 tttagacaat cggccacttc ggttagaaga gtttgaaaaa catgtcaatc agatcattta
    23701 tgtctctgcg acgccaggac catatgaaca tgaacaaaca gataccgtta tccaacaaat
    23761 catccgtccg acagggctgc ttgacccagt gatcgaagtt cgtccaatca tgggacaaat
    23821 cgatgatcta gtaggcgaaa taaatgaacg agtcgaaaaa gaccagcggg tgtttgtaac
    23881 gacattgacg aaaaaaatgg cagaagacct cacagattat ttcaaagaat tagggatcaa
    23941 agtcaaatat ttgcatagtg atatcaaaac gctggaacga acagaaatca ttcgagatct
    24001 tcgattaggt gaatttgatg tgttagttgg aatcaatttg cttcgtgaag gattagacgt
    24061 acctgaagtt tcccttgttg ctatcttgga tgcggataaa gaaggctttt tacgtagtga
    24121 acgttcctta gtccaaacga ttggacgagc tgctcggaat gaagaaggta aagtaatcat
    24181 gtacgcagac aaagtaacag attctatgcg tctagcgatg gatgaaacgt caagacgtcg
    24241 tacgattcag cagaagtaca atgaagaaca tgggatcgtt ccaaaaacga tcattaaaga
    24301 aatccgagat ttgatttcta ttacgaaaga atcggaagat gatacaaaag aagcggtaca
    24361 agtctcgtac gaagaaatga cgaaggaaga aaaagacacg ttattgatga aattagaaaa
    24421 agaaatgaaa gatgcggcaa aagctttgga ttttgaaaca gccgcgaatg tgcgagatat
    24481 gattttagaa ttaaaagctt caaagtagga ggacaacatg gctaacgata aaattacgat
    24541 tcatggtgca cgtgcccata acttgaaaaa tatagatgta acgattccac gagataaatt
    24601 cgtggtcgtt acaggtttgt ccggttctgg aaaaagttcc ctagcatttg atacgctgta
    24661 cgctgaaggg cagcggagat acgtagagag cctttctgct tatgctcgtc agtttttagg
    24721 acaaatggat aagccggacg tagatagcat cgacggattg agtccggcga tttctattga
    24781 tcagaaaaca acaagtaaaa atcctcggtc gacagtaggt actgtgacgg aaatcaatga
    24841 ctatttacgc ttgttgtttg cacgtgtagg acatccgatt tgtcccaacg atcatatcga
    24901 gattaccagt caatcagtag atcaaatggc agatcaagta atggctttgc ctgagcgcac
    24961 aaagatccaa gtgttggcac cgatcgtggt aaagaaaaaa ggacaacata aaaaaatatt
    25021 cgaacgaatc caaaaagagg gatacgtccg cgttcgagtc gatggtgaga tctatgattt
    25081 aagtgaagtg cctgagctgg agaaaaacaa aaaacatgat atcgcgatcg tcatcgaccg
    25141 gatcattgtg aaagaaggga ttcgttctcg cctatttgat tctttagagg cggccctgcg
    25201 attagcagac ggctatgctc tggttgacgt gatcggtgaa gaagaaatgt tgtttagcga
    25261 acactatgcc tgtccttatt gcggatttac tgttggcgaa ctagaaccaa gactgttctc
    25321 attcaatgcg ccttttggag cttgtccaga ctgtgatggt ttaggtgtca aattagaagt
    25381 cgatcaagat ttagtgattc cagatagaac gaagacactt agtcaaggtg ctatcgttcc
    25441 atggaatcca atcagctctc agtattatcc tcaaatgtta gcgcaggctt gtgaaagttt
    25501 cggtatcgat ttagatacac cattcgaaga attaccggaa gagcatcagg agatcatctt
    25561 gaatgggaca gatgatcttt tccatttcca ttatgaaaat gattttggtg gcgttcgcga
    25621 tgtagaaacg actttcgaag gggtattgaa gaatatcgag cgtcgttatc atgatacgaa
    25681 cagtgatttc acgcgtgagc aaatgcgtct ttatatgaca gaattaactt gtcagacatg
    25741 taaaggttat cgattgaatc cccaagctct atctgttcaa atcaatggaa cgaatatcgg
    25801 gcaaacaaat gagttgtcta ttcaaaaagc agtagatttc ttctcaaact taacgttatc
    25861 tgaacaagag aaagtaattg ccaaaccgat tttaaaagaa gtaaatgaca gactttcatt
    25921 cttggaaaat gtgggactag actatctaac tttgagtcgc gcttccggaa cattatctgg
    25981 gggagaagcg cagcgaatca gattggctac acaaattgga tcgaatcttt ctggagtttt
    26041 gtatatttta gatgaaccat cgatcggatt gcatcaacgc gacaacgatc gactgattgg
    26101 ctcattaaag aaaatgcgtg atcttggcaa caccctcgtt gtagtcgaac atgatgaaga
    26161 tacgatgtgg gcagcagatt atttgattga cgtcggacct ggggccggag aacaaggcgg
    26221 acaaatcgtg gctgcaggca ctcctgaaga agtagctaat gatgaaaatt ctttgacagg
    26281 gaaatatctt tcagggaaaa aatcaatccc tgtaccaaaa gaacgccgta aaggtaatgg
    26341 gaaagcaatc aagatcactg gtgcttcaga aaacaatctg aaaaatatta gtgttgaatt
    26401 tccattagga gaatttgtag cagtcacagg tgtgtctggt tctggaaaga gtacattggt
    26461 caatagtatc ttaaagaaat cgttagcgca aaaattaaat aagaattctg ctaagccagg
    26521 taaattcaag acaatttccg gctacgaaag tatcgaaaag atcatcgata tcgatcaaag
    26581 cccaatcggc cggacgccga gaagtaatcc agcgacttat acaagtgtat ttgatgatat
    26641 ccgtgggtta tttgctcaaa cgaacgaggc aaaaatgcgg ggttataaga aagggcgttt
    26701 tagtttcaac gtaaaaggcg gtcgttgtga agcttgtcgc ggggatggaa ttattaagat
    26761 cgaaatgcac tttttgcctg atgtctatgt tccttgtgaa gtatgtcatg gtaaacgata
    26821 taattctgaa acattagaag tgcattacaa aggaaaaagc attgctgata ttttggaaat
    26881 gacagtagag gatgctgtag aattcttcaa gcacattcca aagattcatc gcaaactgca
    26941 aacgattgtt gatgttggct taggttatgt gacgatgggg caaccagcaa cgacattgtc
    27001 cggtggtgag gcacaacgga tgaaacttgc cagtgaattg cacaaaatct ctaatggaaa
    27061 gaatttctat atactagatg aaccaacgac aggacttcat agcgatgaca tcgcccgctt
    27121 gttgcatgta ttacaaagat tagtagatgc tggtaacaca gttttagtga ttgaacacaa
    27181 tctagatgta atcaaaacag cagattatat cattgattta ggaccagaag gtggagaagg
    27241 tggaggaacg atccttgcga ctggaacacc agaagaaatc attaacgtaa aagaaagtta
    27301 tacaggtcac tatttgaaaa aaataatggt ataaagagga tagatagctg agatagttaa
    27361 aaaaacataa aaaaatgaat ttttgcttgt tttattaata tcagtgttct agaatcatta
    27421 catggtagtt ctttctacac tgattggtat agataaaaac ttcctataag ttcaatccgt
    27481 tcaaaaaaga attgagcaat cggaggactt tcctttgatt gcttttttct ttatggtatg
    27541 atattccttg tgtagttgga aaagaaaaac aagagattat gagtaagtga gagataatga
    27601 tgaacagtat tgaaaatgaa gaatttatcc ctatattatt aggaagcgac atgaacgttt
    27661 atggtatggc acgttctttt aatgaagcat acggcaaaat ctgccaagca tatgcttcgg
    27721 atcagttagc ccctacccgc tacagtaaaa ttgtcaatgt agaagttatt ccaggatttg
    27781 ataaagaccc tgtatttatc gagacgatgc ttcgtttggc aaaagaaaga tattctgata
    27841 agagtaaaaa atatcttttg attgcttgtg gtgatggata tgcagaattg atctcccaac
    27901 ataaacaaga gctgtcagaa tattttatct gtccatatat tgattattct ttatttgaaa
    27961 ggctgatcaa taaagtaagc ttttatgaag tttgtgaaga atatgatctt ccgtatccta
    28021 aaacattgat cgtcagagaa gaaatgttag taaatggaca tttggaacag gaattgcctt
    28081 ttgaattccc agttgctttg aaacctgcaa acagtgtgga gtatctttct gtccaatttg
    28141 aaggaagaaa aaaagctttt attttagaga ctagagaaga gttcgattta attttaggcc
    28201 ggatatacga agccggttat aaaagtgaaa tgattgtaca agattttatc ccgggtgatg
    28261 atagtaatat gcgtgtgcta aatgcgtatg tagatgaaga tcatcaagtt cggatgatgt
    28321 gccttggtca tccactatta gaagatccta caccagcatc gattggtaat tacgttgtga
    28381 tcatgccaga ttataacgaa aaaatctatc aaaccattaa ggcatttttg gaaaaaatcg
    28441 aatatacagg ctttgccaat ttcgatatga agtatgatcc tagagatgga gaatataaat
    28501 tatttgaaat caatttgaga caaggtcgta gcagtttctt tgtgacattg aacggcttga
    28561 atctggctcg ttttgtcaca gaagatcgag tgttcaacaa accctttgtt gaaacgacct
    28621 atggaacgaa tcaatcagat aaagcaagat tatggatggg tgtgcccaaa aaaatctttt
    28681 tagaatatgc tcgggaaaat gaagacaaaa aactagctga gcaaatgatc aaagaaaatc
    28741 gttacggtac tactgtattt tatgaaaaag accgatcaat caagcgctgg ttgttgatga
    28801 aatatatgtt ccataactat attccaagat tcaaaaagta ttttcatgtg aaagaaggct
    28861 agttcatgga gaattttttc agtattttag gcggaatggg cacgatggcg acagaaagtt
    28921 ttgttcgctt gatcaaccac cgaacgaaag ctacaaaaga tcaagaatat ttgaattatg
    28981 tcttattcaa tcatgcaaca gttcctgatc gtacagctta tattttagat cgatcagaag
    29041 aaaatccaat gccgtttctg ctggatgata ttgagaaaca aaatttattg cgaccaaact
    29101 tcattgtgtt gacttgtaac accgcacact acttttttga agagttacaa gcggcaacgg
    29161 atattcctat cttgcatatg ccaagagaag cagcaaatga acttgtccgt cagcatacga
    29221 cagggagagt agcgattcta ggaacagaag gaagtatgaa agctggaatc tatgaacgcg
    29281 aagtcaaaaa tcttggtttc gaaacagtga ttcctgatac tgcgcttcaa gaaaaaatca
    29341 attacctgat ctatcatgag atcaaggaat cggattattt gaatcaagag ctctattacg
    29401 aaatcttaga ggaagcggta gagcgcctaa actgtgaaaa agtcatccta ggttgcacag
    29461 aattatcttt gatgcatgaa tttgctgaag ataatcatta cccagtgatc gatgctcaat
    29521 ctattttagc ggatcgaacg atcgaacgtg cattagctga aagaagcgag gcattggata
    29581 cagcatcgga aaagtaaaaa aattggattt ggggcaaata tcctaaaaga tatttggtcc
    29641 aaatcttttt gtaaaagaaa aagaaaactg gtaatgatac gcccgggatg atataatttt
    29701 attatgcaca atgtgagagg ggttcgtaaa tatgacagat aatttgcaat tagtcatcat
    29761 aacaggtatg agtggtgcag ggaaaacagt agctatccaa agttttgaag atatgggcta
    29821 tttttgtatc gataatatgc cgcctcgatt gattccaaaa ttctgggaat tgatcaaaga
    29881 atcaggtaaa gtcacaaaaa tggctttagg agtggatttg cgttctcgtt ccttctttga
    29941 agaaatccaa aacatgctga tcgaaatcga aaatacgaac ttcatcgaca cttctatctt
    30001 atttttagat gcttcagacg aagaactagt ggctcgctac aaagaaacaa gacgagcaca
    30061 tccaatggcg atggacggtt tgatcactga agggatacgt aaagaacggg cgatactaga
    30121 cgacttgaaa gcccaagctt ccgtgatcat tgatacgaca acattgacac cacgacaatt
    30181 acgtgaaaaa atcaatgagt cattcaaatc aaagggagac caaggatttc ggatcgaatt
    30241 tgtatcattt ggttttaaat acgggttgcc gatcgattcg gatattgtga tggatgtgcg
    30301 ttttttgccc aaccctcatt atatcccgga actaagacca ttgaccggaa aagatcagcc
    30361 agtctatgat tatgtgatgt cctttgatga aacgcaatca ttctaccata aatttttgga
    30421 tcttctggaa actgtattgc ctggatacat taaagaagga aaaagcagct tgacagttgc
    30481 aatcggctgt acaggcggtc aacaccgttc tgtggcattg actgaacgtt tggcaaatgc
    30541 tttagggaaa aactataaag tcaatgtgac acatcgggac aaggataaaa ggaaagagac
    30601 ggtgaaccgg tcgtgaaaat gaaaacctac cggataagaa aaccaaagat cgtagtggtc
    30661 ggcggtggca ctggtctgcc agttatcctg aaaagtttac gaaatcaagg agcagatatc
    30721 acagcagtag tgactgttgc agatgatggt ggaagcagcg gtgcaatcag agaatcgatc
    30781 gctatggctc ctcctggtga cttgagaaat gtcttagtgg cgttatcgga tatgccacaa
    30841 ttctatgaag atattttcca ataccgtttc aaaaaggaag atcagttttt agccaatcat
    30901 acgatcggta atctgatcat tgccgcagtt tccgagatgc ggggaagcac ttatgaggcg
    30961 attcaattat tagcaaaaat gatgcatgta gatggacatg tttatccttc ttcagaaact
    31021 cctttgacct tgcatgctgt ttttaaagac ggaacgactg cagtaggaga atctaaaatc
    31081 gcgatcaacc gtaaaaccat tgaccgtgtg tatgtctgca acacaaatga taaaagtgaa
    31141 gccaaagcgg ctcgaaaagt cgtttcagca attatggacg ccgacatggt cgttttggga
    31201 cccggaagtt tattcaccag tatccttcca aatttagtga taccagaaat cggcgaagca
    31261 atgctcaaga caactgctga aaccgtctat atctgtaata tcatgaccca aaaaggggaa
    31321 acggaacatt tcacagatgc cgatcatata cgtgttttac acaagcattt gaatcagcct
    31381 tttatcgata cagtattggt caatacggaa aaagtgcctg aagattatat ggacccagag
    31441 atctatgatg agtatctagt acaagtcgca cacgacttca acggattgag aaatgaagga
    31501 tgtcgagtga tttccaccga ctttttagaa ttgaaagatg gtggtgtctt ccacgatgga
    31561 gacaaagtag tagaagaatt gttccgttta gttttcggtt caaaatatta agcaatttat
    31621 tgttggagaa aggaggagaa taggatgtca tttgctgcag atgtgaagaa agaactaact
    31681 ggtttggaag ttcatcgaga acatgcgaaa gcggaattag ctgctttgct gcgaatgaac
    31741 ggctctttag gtattgtgaa ccagcagttt attttgaacg tccaaacaga aaatgctgca
    31801 attgccagac gtatctattc tcttttgaaa gatcattatc aggtacgaag tgagctactc
    31861 gttcgtaaaa aaatgaaatt aaaaaagaac aatgtctata tcgtccggtt gaagcaaggc
    31921 acaaaagatg tgttgatgga tcttgatatc atggatggta tgatgttcaa tggacacgtt
    31981 tcggacgaga ttatgggaaa ttcgcaaaaa atgcgttctt acttacgtgg tgcttttatg
    32041 gcctcaggtt cagtcaataa tccggaaacg agtcgttatc atttggaaat attttctatt
    32101 tatgaacagc ataaccaaga catttgcgat atgttaaatt attacggtct acatgctcga
    32161 acgcttgaac ggcgcaatgg ctatatttcg tatttaaaag gagcagaaaa aattgctgat
    32221 ttcttaacat tgattggtgc aaccaactca atgctccgat ttgaagatgt tcgaatcgta
    32281 cgggatatga gaaattcggt caatcgtcta gtcaattgtg agacagcaaa tctgaacaag
    32341 acgattgatg cggcttctaa acaaatcgaa aacatcgaat tgatcgaagc aaaggtcggt
    32401 ctacatgccc ttcctgaaaa acttcaggaa atcgcagaac ttcggcttca acatccagag
    32461 gtcagcttga aagaattagg ggaaatgatt ccctcaggtg caatatcaaa atcgggaatt
    32521 aatcaccgaa ttcgcaaaat aaatgaattt gcggaaaaac tgcgtgaaga agcagtttaa
    32581 tccaaagaaa aaactgatac atgaagcagg agatgcgaat gtatcagttt tttttaaaag
    32641 ctatacttgc ttttcttccg tcaaactata attccaactt tactggagta acataatgtt
    32701 gaaaggcttc tattgttttt taatacaatc gtataaaaag cggggagaca actgaatgaa
    32761 gattttagtt ttatacataa acttttgctt aatatagaag tcctgatata gataggatca
    32821 agtatttatc tataactgga gattaattaa aaactggaag gaactgctcg atcaaccttg
    32881 agaactgttt ttcttacttc tggtcaagat tctcgtggtt ggtggataag gatggttgat
    32941 aagttcattg gattagctag tcgaaaacaa ccaggtgtaa ttaatgtaga agttttaaca
    33001 aggggatgga gtgatttatt cagtgataat cataagttca taaatagtaa ttgggatgta
    33061 tggttggtat acgttatacc tgaacttgaa ctatcaagat ttggtttaga atttgagaat
    33121 cgatgtttat aaagggaggg caaaaaatgt gcttttttac aacttttact atcattatga
    33181 ttgcagtact ttttattttt ctagatatag caaagcgaaa tacagcattt ttattatatc
    33241 gggttttact tcgagcaggt ctcataacat ttatatcgat cgttggattt tttctattca
    33301 cagttattgt atttatttgg agaactacag caccaccatt gccagagatt acatatggag
    33361 aatttccgtt tagtcttgaa tatgaaatag atgaggaaag aattttgatt gaagatacgg
    33421 tgattgcaga atttatagga agttttagag ggaatgtgac aactcaacct agacgaagtt
    33481 ggagtataaa acttttaaat aatagtggag agttgaaagc atttcattat gaattcttaa
    33541 taatagaaag tgaagatgta acaatcactt taagtagtgg ctctgctgga tattttatga
    33601 atgatggtgg aagcaagcca cagctcacag tccgtgatcg tattgcaggt tttatgcatt
    33661 tttctcacta tgacttagaa gaagctcgta aaatacttgc agaatatggg atcacattaa
    33721 tcaattggga atatgcgcca ccgataagaa attttttcaa tgattattat tagtcttata
    33781 aaaaacagaa tgtaaaattt atgtgcgcga gtatttagtt ttccattttt tgtttgatag
    33841 atatatagca ttgttgaagc atgggatagt ggtgccaatt ttatcaatga ggttggtcag
    33901 gcagttaaca taattggtga tgctataaat ccatttaatt ggaattggag gaattaggtg
    33961 tggaaacagt gagattatgg atattcatga aaaattttcg ttcggctttg agatatgtta
    34021 ttctggaatc aaaatcaggt tattatctga ttgacacaga tcactatact ttttggggag
    34081 gctacctttt tccgattttt aattggataa tcccccataa ggttatgaaa attaacttgc
    34141 ctgcagaaga aataaataga ttaatactca acaaagattt acaaaggaaa agagagaaag
    34201 aacattctaa tgttgcttgg ataggtccag catttgcagt agtgacttct tcaattgtcg
    34261 gtcctatgct agagagtatt tatagtgatt tttctattgg aatacgttat ttatttgtta
    34321 ctttaagtat agctgttctt ttgtgcataa agggttatgt tagcaagaag aataaagata
    34381 ttttaacact aatcggtgta aacaatttat ctagtactaa aattatactg tttcctgaat
    34441 ctataaaaga aggatcaagg ttgttgataa tttttataat gcttatactg ttttctgttt
    34501 tatttggggt gatgtttata
//
LOCUS       DAFEEZ010000027        33235 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000027
VERSION     DAFEEZ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33235
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.027"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            121..363
                     /locus_tag="LP245_001357"
     CDS             121..363
                     /locus_tag="LP245_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBL1519286.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            360..830
                     /locus_tag="LP245_001358"
     CDS             360..830
                     /locus_tag="LP245_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL1519287.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            958..2172
                     /locus_tag="LP245_001359"
     CDS             958..2172
                     /locus_tag="LP245_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBL1519288.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            3161..3370
                     /locus_tag="LP245_001360"
     CDS             3161..3370
                     /locus_tag="LP245_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HBL1519289.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            3482..5095
                     /locus_tag="LP245_001361"
     CDS             3482..5095
                     /locus_tag="LP245_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1519290.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            5130..6341
                     /locus_tag="LP245_001362"
                     /pseudo
     CDS             5130..6341
                     /locus_tag="LP245_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            6364..7290
                     /gene="glsA"
                     /locus_tag="LP245_001363"
     CDS             6364..7290
                     /gene="glsA"
                     /locus_tag="LP245_001363"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBL1519291.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            7498..8958
                     /locus_tag="LP245_001364"
     CDS             7498..8958
                     /locus_tag="LP245_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519292.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            9179..10942
                     /locus_tag="LP245_001365"
     CDS             9179..10942
                     /locus_tag="LP245_001365"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBL1519293.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            11026..11484
                     /locus_tag="LP245_001366"
     CDS             11026..11484
                     /locus_tag="LP245_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBL1519294.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            11593..12276
                     /locus_tag="LP245_001367"
     CDS             11593..12276
                     /locus_tag="LP245_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBL1519295.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            12423..13037
                     /locus_tag="LP245_001368"
     CDS             12423..13037
                     /locus_tag="LP245_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBL1519296.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            13053..13259
                     /locus_tag="LP245_001369"
     CDS             13053..13259
                     /locus_tag="LP245_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519297.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            13800..14930
                     /locus_tag="LP245_001370"
     CDS             13800..14930
                     /locus_tag="LP245_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL1519298.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            15022..15777
                     /locus_tag="LP245_001371"
     CDS             15022..15777
                     /locus_tag="LP245_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL1519299.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            15835..17874
                     /locus_tag="LP245_001372"
     CDS             15835..17874
                     /locus_tag="LP245_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBL1519300.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQVTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKIRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(17983..19134)
                     /locus_tag="LP245_001373"
     CDS             complement(17983..19134)
                     /locus_tag="LP245_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBL1519301.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(19288..19818)
                     /locus_tag="LP245_001374"
     CDS             complement(19288..19818)
                     /locus_tag="LP245_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBL1519302.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(19917..20267)
                     /locus_tag="LP245_001375"
     CDS             complement(19917..20267)
                     /locus_tag="LP245_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBL1519303.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(20424..21953)
                     /gene="ahpF"
                     /locus_tag="LP245_001376"
     CDS             complement(20424..21953)
                     /gene="ahpF"
                     /locus_tag="LP245_001376"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBL1519304.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(21963..22526)
                     /gene="ahpC"
                     /locus_tag="LP245_001377"
     CDS             complement(21963..22526)
                     /gene="ahpC"
                     /locus_tag="LP245_001377"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBL1519305.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(22670..23332)
                     /locus_tag="LP245_001378"
     CDS             complement(22670..23332)
                     /locus_tag="LP245_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1519306.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            23516..25162
                     /locus_tag="LP245_001379"
     CDS             23516..25162
                     /locus_tag="LP245_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBL1519307.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            25153..26235
                     /gene="uxuA"
                     /locus_tag="LP245_001380"
     CDS             25153..26235
                     /gene="uxuA"
                     /locus_tag="LP245_001380"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL1519308.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(26343..27896)
                     /locus_tag="LP245_001381"
                     /pseudo
     CDS             complement(26343..27896)
                     /locus_tag="LP245_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            28044..29185
                     /locus_tag="LP245_001382"
                     /pseudo
     CDS             28044..29185
                     /locus_tag="LP245_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(29311..30390)
                     /locus_tag="LP245_001383"
     CDS             complement(29311..30390)
                     /locus_tag="LP245_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1519309.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(30493..30933)
                     /locus_tag="LP245_001384"
     CDS             complement(30493..30933)
                     /locus_tag="LP245_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1519310.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(30990..31400)
                     /locus_tag="LP245_001385"
     CDS             complement(30990..31400)
                     /locus_tag="LP245_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBL1519311.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(31580..32014)
                     /locus_tag="LP245_001386"
     CDS             complement(31580..32014)
                     /locus_tag="LP245_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1519312.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(32114..32962)
                     /locus_tag="LP245_001387"
     CDS             complement(32114..32962)
                     /locus_tag="LP245_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1519313.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
BASE COUNT        11404 a         5753 c         6397 g         9681 t
ORIGIN      
        1 tggagatgtt caataagatt attggtgctt aattattttt attgtagtgc tgatatgaga
       61 atgttataat tggggtataa aacatacaaa taaatttgct gaaaaatgag gtatcaaaat
      121 atggaaaatg aattactgga aaacttagga agacttcaca caactgaact tggcgttatt
      181 agaattaaaa agaacttatc tttgaatgta gaaaatgtaa ttgaatggtg caaagaaaaa
      241 attagccttt ctaatgcgga aatcacaaga aaaggaaaaa actggtatat aacgattgat
      301 aattgtatta taacggtaaa tgcgtacagt tataccgtta tcactgctca caaggtaaaa
      361 tgataaattt ttctataaag gaattaaacg catttgcagt tattgggcag gaagtagaac
      421 tgactaatta tcaaaaaaag aatattcaga ttagtacaca gttttggaga aagtttaaca
      481 gtagtttgaa aaaagcgtat ctttcacaat caggaaattg ggtaaaatat gcttttatgg
      541 aaagaagaaa tggaaaactt tattatttct gttctattcc ccaaagaacc attaccccag
      601 agggctttct gtataaagaa ataccgtctt ataaatattt ggttgtggag catattggtg
      661 ctatggataa aatatatgaa acttatggca agatttatga agaaattatt cctagtacat
      721 cgtatattcc tataaaagat attatcctac actttgaaaa atacgattat cgttttcatt
      781 ggaatagtga taattcagtt attgaaattt ggatacctat tcaagattag aagcaatttt
      841 atatccatac acacaaagca gttagtctta ggattgactg ctttttctat acagattttt
      901 aatgacaggc aattatcaat tatggtagtt gccttttttg attggaggaa ttgaagaatg
      961 aatgataaaa actttattga agaactaaga caaaagcgtg aggaatacgg agtaacacaa
     1021 acaaggcttg ctgttgcctg tggtatcagc cgtgaatatt acaaccgcat tgaaaaagga
     1081 aaacagccat tgaatgacga attaagagaa atcatagaaa aacagattga gcgtttcaat
     1141 ccgcaagaac cactattctt attgattgat tactttcgtg tccgctttcc tactacggac
     1201 gcattggcga ttatccgtga tgtattacaa ctgaaatcta attacatgct ttatgaagat
     1261 tatggaaaat acggatatga aagcaaatat gtacttggcg acatcaatat catgtgttcc
     1321 atgcaggagc atttaggtgt tttattggaa ctgaaaggca aaggctgtcg gcaaatggaa
     1381 tgttatctgc tggcacagga acgctcatgg tatgacttca tgctggattg tatgacggct
     1441 ggtggtgtga tgaaacggct tgatttggct atcaatgata aagcaggaat attggatatt
     1501 ccaaagttaa aggaaaaata caaggctggc gaatgtatgt cctacttccg tatgcagaaa
     1561 gattacagcg gtacagaaaa atgcggtagc gatttaccaa agaatacagg agaaacctta
     1621 tatctcggtt caacaagtag cgaattatat atgtgtgctt atcagaaaaa ttatgagcag
     1681 tatgtcaaga atggcacaga aattgaagat acggagatta agaaccgttt tgaaatacgc
     1741 atgaagaacg aacgagccta ttatgcggtt gtagatttac tgacctatcg ggacgctgaa
     1801 cgcaccgctt tttctatcat caatcattat gtccgctttg ttgacagaga ggacgacaag
     1861 ccaaaaagtc aatggataac aaatgatgat tgggcatggt ttgtagggga aaacagagag
     1921 ccgatacgct taaccacaaa gccagagcct tacactttac aaaaagcgtt gcattggcta
     1981 caaagacaag tcgcaccaac cataaaaatg gtacaggcat tagacagaga aaatcgtaca
     2041 acgatactga aagatatgat tgagcaggca gaactaaaag acaagcataa acatttatta
     2101 caattagaga aatcaaccat agaagaacgt atagataccg ctgttccaca agagaatgac
     2161 ggtatttttt aatgtaattg aaaaatttca gatttagtca gcaaagagct gttttcattc
     2221 cctatgtgaa gtgaaagaag aaaaataaat tttttattaa atctgcaaca aaatggctac
     2281 ttgcgtacag atatggtgcg agaaaaggaa atctaaactt tttttgaaaa taggtcatta
     2341 aatcggggct tgctgtccct atatgaagtg aaagaagaaa aaagttttga aaaaatgacg
     2401 gaaattcgtg attagtggac agtcttctgt gaaaagagga aaaacatcat cattttgtat
     2461 tcaaacaggc attagcagtt gagtgttgat gtgaaaagat gaaaatactt tgttctcaac
     2521 ttaacaattt aaggtttccg ttccctatat ggtgcaaaga aaatatttca ttctattgtt
     2581 ggcagtaacg gtatggtttg ggtagttagg gtgtgaaaag gaaaatattc ttttttcatc
     2641 atcaacttag caaaatgaca ttttctatcc ctatatggtg catgaaaaga agttaaaatt
     2701 tttccattta aacttagcaa atggacgttt gctgtacaga tagtagtgaa aaaggagaaa
     2761 atcaaccgtt gattgccaaa atgaaccgtt ccatttgtac taataatgga aaaagttttg
     2821 gattttggtt acgtttctcc tcttttccaa cgcgatatat aggaaagacg atttttttct
     2881 ttcaatcgtt ctttgacaac tgaataaagc tattcaatac gtttgacaga cagctagccg
     2941 ttgaaacaaa tacgccacga cctttcccct gcaagagcga gcgaaaacct atttgtgttc
     3001 ttgtaaaaga tttgtcctct tttatcgcca tgacctgtac tgtcagataa tgatactccc
     3061 gtacagccac agcttgagca ttaagagcgt cgcacgcaat gggtacggct acataagaac
     3121 tatgcagagg tggaactcct gtgggctatg acaaaagccg ttgaattgct tagaaagatt
     3181 ttacagaaag ggggtatgtg ttattgataa tgctgtaaaa acaattcaaa agaaaaatgg
     3241 caagtgtggc attggcaaca gaggaaagac aaagattgta gtaaaagagc atttttccga
     3301 aaagggcaaa acaatggaag aacttctaac tgatgtcatg ctggaaaaag caaagcagac
     3361 aatcgcataa aatcggtgca gttgtaagaa atagattgaa tgacaaaaag tacccgtgtt
     3421 atactttact tgcaagcagg tattgtaaac acgggttagt tataaaggag gataactgac
     3481 aatgaaacaa cagatttaca atactgcact ttatcttagg ttaagccgag atgatgaatt
     3541 acagggcgaa agttccagca ttaccacaca gagaagtatg ttgcgtttat atgcaaaaga
     3601 acatcatttg aatgtcattg atgaatatat tgatgacggc tggtcgggaa caaattttga
     3661 cagaccgagt tttcaaagaa tgattgagga tatagaggca ggaaaaatca actgtgttgt
     3721 aacgaaagac ctttcccgtc ttggcagaaa ttatattatg acaggacaat atacagaatt
     3781 gtatttccct agtcataatg tccgctacat agcgattgat gacggtgtag acagcgaaaa
     3841 aggcgaaagt gagattgcac catttaagaa catcatcaat gaatgggtgg caagagatac
     3901 aagccgtaaa gtcaaatcag catttaagac aaagtttgcg gagggggctc attacggtgc
     3961 ttatgctccg ttaggatata agaaacaccc tgacatcaaa ggaaaactgt tggttgatga
     4021 tgaaacaaaa tggattattg aaaaaatctt ttccctagcc tatcaaggtt acggaagtgc
     4081 aaaaatcaca aagcagttaa gagcagaaaa agttccgaca gcgtcatggc taaattttac
     4141 aagatacggt acttttgcac atatctttga gggaaaaccc gaaagtaagc gttatgagtg
     4201 gacgattgct catgtcaagg cgatattgaa aagtgaggtt tatatcggaa acagtgttca
     4261 caatatgcag tctacggtat cgttcaagag caaaaagaaa gtgcgtaagc ccgaaagtga
     4321 atggtttcga gtagaaaaca ctcacgagcc gattattgac aaggaagtgt tctatcgtgt
     4381 gcaggagcag ataaaatcaa gacgcagaca gacaaaggaa aaggcaacgc cgatttttgc
     4441 agggcttgtc aagtgtgcgg attgtggttg gtctatgaga tttggaacga ataagacaaa
     4501 taaaacgcct tacagttatt atgcttgcag ttactacggg cagtttggca aaggtaattg
     4561 ttctatgcac tacattcgtt atgatgtgct gtatcaagcc gtattggaac gcttgcagta
     4621 ttgggctaag gcagtacagc aggacgaaga aaaggtattg aacaagatac agaaagctgg
     4681 caatgcagag agaatacggg aaaagaagaa aaaggcaagt acattgaaga aagccgagaa
     4741 cagacaaaat gagattgacc gtttatttgc gaaaatgtat gaagatagag cctgtgagaa
     4801 gataacagag cgaaattttg tgatgttgtc cagcaagtac caaaaagaac agatagaact
     4861 ggaacagcag ataacaagcc taagagaaga actaagtaaa atggaacagg atatgatagg
     4921 tgctgaaaag tggattgagt taatcaagga atattccgta ccaaaggaac tgacagcacc
     4981 attattaaat gccatgatag aaaaaatcct catacatgaa gcaacaacga atgaggataa
     5041 cgaaagaata caggaaattg agatatatta ccgatttatt ggaagagttg agtaatcaac
     5101 aagagtaata tttttaacta agggaaaccg gcggtgtcta tacttgggtc agtcgcacat
     5161 tgggaaaacg attcggtttt gccgcaatct ttttccaatg gtttgagata acagttggct
     5221 acttgaccat gctgtatttc ttaactggtg cattatccta tgcaacgggt attggtgcta
     5281 tacaaaacaa taaatatctg aaattggcaa tcctattgat tattttctgg gctattttac
     5341 tctcacagtt aaaaggaacc aaatacactt cattgattgc tcggatcggt tttgtagctg
     5401 gtatcttgtt gccagcatta gtcttgtttg gcttagggat ccattatgtc gcttcaggcg
     5461 ctccactaca aacgatactg tctatgaaaa cattgattcc tgatttttcg aaattgccta
     5521 cgctggttgt ttttgtttcc tttattttag catatatggg cgtagaaaca tctgccagtc
     5581 atgcaaatga aatggaaaac cctaaaaagg attatccatt agcaatgttt gtattggtta
     5641 ttctggcaat cattttagat acttttggcg gattgaccgt cgctactaca gtacctcaac
     5701 atggtttgtc tcttaataca ggggtgattc aatcgttaga attcctatta agacacattg
     5761 atccaaatct tgcatggatt gcgaaaattc ttgcgattct tgtttgttta ggtgtcatcg
     5821 gagaaattgc ttcttgggta acctctcctt caaaagcact tcacgtagca gcagaagaag
     5881 gattacttcc tgaatatttt gcaaaagaaa acacacacgg tgttcctgct catttgatga
     5941 tcgcaaatgg gatcgttgca acaatctggg cagccgtctt tacattaagc ggcgggggga
     6001 ataatctttc atttcttgca gcgatgtcat tgactgttgt aatctacctg atgttgtact
     6061 ttatgttttt cgcgggctat ttgaagctgg tttttaaaga tgacagtctt gaaagagcct
     6121 atcaggttcc aggcggaaaa gttgtaaaag taatcgttgc ttgtttaggt cttttgactt
     6181 cactttttgc tttttgtatc tcatttgttc cacctgctag tatcgcagct ggacagcatg
     6241 ggatttatga aacgattctg attgtttctt atcttatcgt cttagttatt ccatttacga
     6301 tctacgcatg ccgtcataaa ttccagcatg cagaaaaata aaaaatgaaa gctggttatt
     6361 caaatggaag taaaagaatt agaacaattg attggaaaaa atttccacta ttatcaaaca
     6421 ggacaagtgg cggattacat tccagcatta gctgaagtgg atcccaaaca attaggtatg
     6481 gcgatttatg atttggatac aaaacaactg attgagggag gagacgccga tgtgcgcttt
     6541 gccatcgaaa gcatgtcaaa agttcccgta ttgttattag caatcaaaga caacggaata
     6601 gaaaaagtct ttcaaacaat caacacggaa ccaaccggtt ttgccttcaa ttctatcatg
     6661 aatatggaaa tcaatcatcg caaacatcca atgaatcctt ttgttaatgc aggagcgatt
     6721 gcaacaacct cgttgattgc cggtaaagat gcagatgaaa aatttgagcg aatcttgtca
     6781 tttatgaaag agatctgtga tgatcctaat atcacattga atgaagaaat ctatcattct
     6841 gaatcaagaa caggtgatat caatcgctct cttgcttact atatgaaagg taatcaaatg
     6901 atcgaaggag acgtaccgga gatactcgat gcttatttca gacaatgctc cctcaatgtc
     6961 accgctacag gcatagcaaa attagctgct gtgctggcaa ataaaggaat tgctccttgg
     7021 aatggcaaac aaatcattac tgaagaaagt gctacaatcg tcaaatcaat tatgacaact
     7081 gctggtttgt atgatgaatc aggagagttt tccgtccatg ttggtgtacc tgcaaaaagc
     7141 ggtgtaggcg gcgggttgat ggcagctgtg ccaaatcgtt acggcatagg tgtcttcagc
     7201 ccggcactag atccatttgg taacagcgca gctggtatcc aattgttgaa agatgtagtc
     7261 aaagaactag acgctgacat ctttgaataa ccattcttga aagaggctgg ggtaaaagtc
     7321 caaacggctc aaagctacct acaatgaggc tgaaattgtg agcttgtttg acttttgtcc
     7381 cagtttcttt ttttattggt ttttgaaagg gcttttctaa ataaaaagga aacaaaaata
     7441 cgatttacag atatgattaa ataaaatcat aagaaaaact ggaggcgtgt atcaggaatg
     7501 ctggaaaatt acatcgagcg aaatatattt agaaaagtgt atctgtgtga acaattattt
     7561 gaattccaag aaatagacat cgaacaaaca gctatttctc taagggtgac tacaccaacg
     7621 atccttcacg atctagaaag tctagccgag tgtctagaat attgtataaa agaacaagta
     7681 agagagaagc ataagtataa actcgtattc aaacatggta ttgctctttc tgagctcaca
     7741 cagtttctgt acggtcaatc ttatttttta aagtttttaa gttattattt taatggtata
     7801 ttcacgagta cagaactggc tgatcttgaa tttatttctt tgagtaaagt atatacaatc
     7861 aaaaaaatcg tattggattt ttttaaagaa aatgattatt tgaaaaataa agaaatcatt
     7921 atcccagaat ttgactcgcg gaacatcttg ctagctttag tacgttatgt caattgggaa
     7981 ggctatgaaa ataaaaatcc gtatgtagaa gaagcttgta acgagttgat tgattatgta
     8041 gagactcatt tttttaaaag aagatattcg gaagatgaaa agtcctttat catacgagaa
     8101 atagagatcg caatcggaag aaaggcattt ccccttggac tgaaagaaga agataagaaa
     8161 agcgcagaaa cgaagccgtt atttcaatta gtctgtcaag gattggaaga gcaaaaagga
     8221 attctagact tacaagaaga agatgtctat tatatttttt ctttgttcaa cagtagaaat
     8281 tataccaatg agaacatgga gctgttaaga aaagatttcg aagttgttta taaaaatttt
     8341 gttctcaatg acctatcact gaatgaattg attttacaga ttattagtat cgctgaaatc
     8401 gacgatgcag aaaattttat tttcaagcaa tcctttttac aatttgtccg tacgttgtgg
     8461 gcagatggac aagtattttt accggaaagg atctatcttc tatcagaaaa agaacaactt
     8521 ctgtacggaa aaattgtaga aatattggaa gagtggaaaa agaaaaatca aatccaacta
     8581 agatggaatg aaaatttcat tcgaaaattc gtcaaaagtc tttctttgat caacagtgaa
     8641 caagcgggga gacaggaaat agaaattttt gttgtttcag aaagttcagt caaacaattt
     8701 ttttatcgaa cccaatttca tttgtatgcg gaagaaggca tcgctgaaat aaatcctatt
     8761 ttatttcgtt cattagaaga attgcctgat gaatgtctat gtgcgaaaaa aagagtggtt
     8821 ttgtgcgatg ctgctagcta tcaaaatgga ttagaaactg aaaagacaaa gatctatcca
     8881 atctcattaa aaggtgcaaa catccatttg tatcatattg ctcaggaact tcacctatta
     8941 aaaaaacata tttcttgatg agaccttaat taggagacct tctacaaagc tttttaattg
     9001 tctgtagaag gtttttattt gagtcctgat tcgtgcgaag atctacttat ataacaagct
     9061 ttctctgaaa tttttttaaa atgctattga cttagagtca actctaagta gtagaataga
     9121 taaagtgtaa caaatctatt ttcattaaaa gaagatagta cggaggagag aatgtattat
     9181 gagtacagta ttacatgtat tggatgcaat caatagcccc gcagatgtca aaaaattatc
     9241 tgttgaggaa atgaaacagt tggcagaaga gatgcgccaa aaaatcttgc aaaaggacag
     9301 cgatgtaggt gggcacgttg gtccgaatct aggtgtagta gaattaacga ttgcgtttca
     9361 ttatgtattt gattcaccaa aggataaaat cgtttgggat gtttcccatc agtcttatgg
     9421 tcataagctt ttaactggtc gaaaaaatgg ttttgaaaaa ggacattacc gtgaagtgag
     9481 cggatattcc aaccaacatg aaagtaaaca tgactatttt acagtggggc acacatctac
     9541 atctatcagc ttagcaacag gtttagctaa agcgagagat ctgaagaaag aatcaggaaa
     9601 tgtggtagca tttatcggtg acggctccct aagtggtggc ttagcttttg aaggattgaa
     9661 caatggtggt gttttacaat ccaatctaat cgtattagta aacgataatg agatgtctat
     9721 tgatgagaat catggcagtt tatataaaaa cttagctgag cttcgtcaaa ccaacggtaa
     9781 aagcagcaat aacctattta aagcaatggg atttgattat cgttacgtgg ataatggaaa
     9841 cgatctggaa acggtgatcc gtttatttga agaagtaaaa gatattgatc atccgattgt
     9901 acttcacgtc catacggaaa aaggtcgcgg ttatcagccg gcaatcgata ataaaatgaa
     9961 atatcattgg catgtaccat ttgatctgtc caccggggag gcaaagcaag taacttctgg
    10021 agaaacattt aatatgatca tcatggatta tttggataag aaaatgcaaa caagtacagc
    10081 tcctattgcc gcagtcaatg cagcgatacc aggcgccttt ggactgaaaa cattccaaga
    10141 aaaacatcca gatcattatt ttgacgtggg gatcgctgaa cagcactcta tcactttcgc
    10201 ttctgctttg gcttctcagg gagtacgtcc agtcgtcttc caatcaagta ctttcttgca
    10261 acgggcatat gatcaattat cacatgattt agcgatcaac gagaatccag tgattatttt
    10321 agtcggtggc ggaacgatct cagctagtga ccgaacacac caaggaacat ttgacattcc
    10381 ttacttatca agtatcccga acatcaaata tcttgctcca gcaacaaaag aggatatgat
    10441 ctctatgcta gattgggcgt tcgaacaaac agcgcagcct gtagcaatcc gaattcctac
    10501 acatggtgta gaacatggta cagctatcgc aaatgattat agtattccag cctatcaaac
    10561 agtaaataat ggaggaaaag tagcaatttt agctttaggc ggttttcttg aattaggaaa
    10621 agaaacagta aaagctttta gaaaaaaagg aatcgaagca acgttgatca atccaggaac
    10681 gatcacagaa aatgacgtag aaacattaga taaattaaaa gaaacacacg aattagtcat
    10741 cacattagaa gatggtagtt tgtcaggagg atttggcgaa aatatcagtc gttattatgg
    10801 tgattcttca atgaacgtat taaattttgg tgcagagaaa gaattcacgg atagcgttcc
    10861 tgtagggcag ctttatgaac gttatcattt aacaccaaaa caaatcgttg aagatagtct
    10921 gcgtgtcttg aatattcaat aattcattat gctcaccatc cagataattg tttatactag
    10981 tatctggatg gttttttcat tataaaaagc aaaggggtgg atgttatgta tcagcaagta
    11041 gaagaatatg tcaaaaagtt ccaagaaaaa tatcctagtt atcaatcaga aaaattaggt
    11101 ttcttttcat ttggggatac agaaaaaatg gcagacgagt tgagcgaact agttgtaaaa
    11161 aagataaaga ctggtacatc aagtggttac gatctgtata aacaagagaa tgagccttta
    11221 ccaaaagttg gtcaattaga cgtggtcctg aatggaaaaa atgaaccagt ttgtatcatc
    11281 aaaaatataa atgtgaccat cttgcctttt agtgaagtca cgaaagagca tgcttggaaa
    11341 gaaggagaag gggatcggac attagcttat tggcggaaag tccatgctga gttttttaaa
    11401 catgcttata aagaagcgtt gaacatagaa tttacagaag agaagctggt cgtatacgaa
    11461 gaatttgaag taattttctt ttagtaagaa aggtctgctg aaagaaatag ctcattattg
    11521 tctcctgaat agaaaagggt tacattttta tatgaagctg tatttttata taacattact
    11581 ggaggagata ttgtggatac actggaacaa atcaaaggcg gagtcgtcgt ttcttgtcaa
    11641 gctttggaaa acgagccgct acacagttct tttattatgg ggagaatggc tttggctgca
    11701 aaagaaggcg gagcagttgg tattcgagca aatacgacag aagatatcaa tgaaatcaag
    11761 cgaatcgttg atttaccggt aatagggatt atcaaaagag attacgatgg gtcagaagtg
    11821 tttattactg cgacagaaaa agaagtggaa gaacttttgg agacgcaagc agaaatcatt
    11881 gcactggatg caacttctcg taaacgtccg acagaaaaaa caactgctga acttgtccaa
    11941 atgattcacg aacacggtcg gttagctatg gcagatattt cgacttttga ggaagcgctt
    12001 caagcgcaag aagatggttt tgatcttttg tctacgactt tagcaggcta tacagaatat
    12061 tcacgaaaga cgcagacacc tgattttgat ttattgaatc aaatcataga acaagtcgat
    12121 atcccagtaa ttatggaagg acatactgac tctcctgaac aagtagagaa agcatatgaa
    12181 ttaggtgctt tttcagtcgt agttggatct attatcaccc gtccgcaatt gatcactaaa
    12241 agatatgtcg aagccgcaag taaagcaaat aactaaaaaa cacgcacggc acagattctt
    12301 gacaaaaaag aaaaattgat agatagttta aagcagattc taagaagatg aaaaaagcat
    12361 tacttttcat tttgtcttca agatctgctt tttaacgaat tttatagaaa gaaggcgaaa
    12421 ccatgtttga acggagtcct tcagaattga cagaacgtga aaattacaag ttgctgattg
    12481 gttcagtcat ccctagacca gtagcagtag taacgactaa atcagcaaaa gatatagtga
    12541 atatcgcacc cttcagttac ttcaatatcg tcagttcgaa tcgacccatc ttatccttgg
    12601 cgatccagag aaaacaagat gcagtaaaag acacagcaaa gaatattctt gagacaagag
    12661 aagctgttat ccatatcctt gatgaggaca acgtagaaga agtaaataaa acagcagcca
    12721 atctgcctaa tgaggaaagc gaactgtacc tgactgactt gactttaact gattcagtaa
    12781 tcatttcagt accagcattg acagaagcaa aagttcgttt tgaaacatcc ttatatgaac
    12841 atgtcgagat acggaataaa aataaagtaa cagctgattt atttttgcta gaagtacaga
    12901 aatatcattt aaatgaaaca gtctatgatg ataagacagg aaggatcgat ccaagaaaat
    12961 tgaatgctgt aagccgtttg gcaggaaatg attatgcagc aataggagaa attttcacga
    13021 ttgcacgtcc cgaataaaaa ggagcactag ttatgttaaa aataagctat aaaccatcga
    13081 cagattcaaa agaaatgaaa aaagaatatg aaacagtgaa tgattttctg caagggcagt
    13141 acttagaagt tccgccattg caagaccatt ttgtcgttac tactgttact ttagatggta
    13201 aggaaataga aatgccagat caaacgatta gcggattgtt taattacttt aacaaataaa
    13261 tatttattcc gaaaagtgaa aaaacatata aaaaaacaca taaaactaaa aaattatcaa
    13321 agaatcctgg tgcaactgaa agaatttgca acgggattct ttcaacttat ttgttatttt
    13381 tttctaaaaa atattaaaga ttgttaaatt tcactatttc atttcaaatt ccattgccta
    13441 atcattagga aaagtctatc atgaactcgt aaatagaata tagtaataac cttgttaggt
    13501 gaggctccta tacaaacata ggctgttgcc cagaaacgtc gaaagtcgcc aatgggtaaa
    13561 acagaaactg ttggattaag gctttttcca atagctaaga atgttttctt tacgttgtat
    13621 agtgctaaaa ctcggacgat gagatgatgc taggtcagaa ttcttgttcg aaaaggtttc
    13681 tgaccttttc tttatatttt tgtgactgac ttatttgatg agacaaactc gctcctcacc
    13741 tgacaagtgg attgctgtgt gaggaggaga tgcggtgaaa aaagatcgat tggtggattt
    13801 tgggtcctta tttgactttg tccatgatcg gtcttttaga agtatacagt gccagttctt
    13861 atcgtttatt gcaagccgat gaaaatacaa aaagtctatt attgcgtcaa ctaattttca
    13921 tatttttgag ttggagcgtg atcttcttag ctcgttcagt caaactacac tatttacttc
    13981 accctaaaat agcaggatac ggtttagcct tatcgatttt ctttttagta ttagtaagaa
    14041 tagggatatt cggtgtcact gtcaacggcg cacaacgttg gatctctctg tttggcattc
    14101 aattccagcc ttctgaactg gcaaatcttt ttttgatttt ttatttaagc tggttttttc
    14161 gtgacggaaa tagtagccca aaagatctaa aaaaaccatt cctgattaca gtaggtataa
    14221 cttttctgat tttatttcag ccaaagattg ctggagcatt gatgatcctt tcgattgcgt
    14281 gggtcatatt ttgggcagcg gcggttccat ttaaaaaagg gatctatcta atcgttactt
    14341 tttctgcatt gctgattgga gcagcaggcg gggtattata tttaggaaat aaaggttggc
    14401 ttccacagat gtttaatcat gcttatgaaa ggatcgcgac tttaagagat tcttttatcg
    14461 atagtcatgg tgcgggctat caaatgaccc attcgtttta tgcactatat aatggtggca
    14521 tatttgggcg gggattagga aatagtatca caaaaaaagg gtatcttcca gagacagaaa
    14581 cagattttat tttttcgatt attacagaag agcttgggct aatcggtgca ttgtgtgtgc
    14641 ttttcttatt gttctcatta tgcatgagaa tcttttgttt aagcagtcgc tgtaaaaatc
    14701 agcaagctgg attgtttctt ttaggattcg gaactttgct attcgttcag acgataatga
    14761 acgtgggaag tatcgcgggg ctgatgccaa tgactggtgt gccattgcca tttgttagct
    14821 acggaggaac aagttatctg atcctttctt taggaatcgg aatcacgttg aatatttctt
    14881 caaagataca ggccgaagag ttggcgctct atcgacctga aaaacaataa agagaaactg
    14941 agaaactctc agtttgaatt atcataaagt acaatctttt atttttcaag cgagaggttc
    15001 ttttagaaag aggaattcgc aatgaaagta tctcaaaaaa tcatattatc tattttgtta
    15061 ctgcttacat tagtagttgg ctatttttcg attgagttta tccatggatt ttcgtctgca
    15121 aaacagagtt caactgtgaa aaaggtagag ccgaaaagta tccctaccac actaaatgtg
    15181 gctttgattg gttcagatgc tcgttcgaaa gacgaaaacg gtcgctcgga ttcacttctg
    15241 gttgcacaat acaaccagaa aacacaacaa gcaaaactga tctctatcat gagagattca
    15301 tatgtcgata ttccaggtta cggaatgaat aagataaatg cagcttactc ttatggggga
    15361 gttgatttat taaatcaaac attaaaggaa aatttcaaat ttgaagctcc ctattatgca
    15421 agtatcacat ttcaagattt tatcgattgc gttaatgaac tgtttcctgg tggagtcaag
    15481 atcgatgcag aaaaatctct agatttagat ggcgtatata taaacaaagg agagcaagtg
    15541 atggatggta atactttact ccagtatgct cgatttcggg aagacaaaga aggagacttc
    15601 gggaggatca gaaggcagca gcaagtgatc aaagctatct ctcagcagct gaaagacgta
    15661 acttcaatat tcaagctacc caaagcggtt gggaaattac ttggtagtat ccaaacgaac
    15721 cttccagaaa gtgtgcttct ggattgtggt atggatttcc tcaaagacat atgttagaat
    15781 aaacaggtat aaatagtgaa ataaaggaat gacaagcaag agaaggagga aaaaatgaaa
    15841 agaagtgaca agcacggcaa aaatcgaaca ggcgcttata ttgccggcgc agtgatctta
    15901 atagcagctg cgggtggcgg ttatttttac taccagcact atcaagaaac ccaagcagta
    15961 gaagctggag aaaagacagt tgagcaattt gtccaagctt tgaacaaggg agattataac
    16021 aaagctgcag aaatgacatc aaaaaaggcg gcaaataaaa gtgcattatc tgaaaaagag
    16081 atcttagata aataccagaa tatatacggt gctgctgatg tcaaaggact tcagatatcg
    16141 aatctaaaag tagataaaaa agacgattct acttacagtt tttcatataa agcaaagatg
    16201 aatacctcat taggtgaatt gaaagatctt tcttataaag gaacattaga cagaaatgat
    16261 ggtcaaacca cgatcaactg gcaacccaac ttggtttttc cagaaatgga aggaaatgac
    16321 aaagtaagcc tgaccacaca agaagcagca agagggaata ttatagatcg aaatggtgaa
    16381 ccattagcaa caacaggcaa actaaaacaa ttaggagtcg ttccaagtaa acttggagat
    16441 ggaggcgaaa aaacagccaa tatcaaagcg attgcttcct ccttcgactt aacagaagat
    16501 gctatcaatc aggcgatttc acaaagctgg gtacaacccg attactttgt cccattgaaa
    16561 atcattgatg gagcaacgcc agaacttcca gctggagcta ccattcaaga agtagacggc
    16621 agatattatc ctttgggtga agcagctgct cagctgattg gttacgtggg agatatcaca
    16681 gcagaagata ttgataagaa tccagaatta agcagtaatg gaaaaatcgg tcgctcaggt
    16741 ttggagatgg cttttgataa ggatcttcgt gggacaacag gtgggaaatt aagcattaca
    16801 gatgcagacg gtgtagagaa aaaagttctg atcgaacatg aagttcaaaa tggcaaagat
    16861 atcaaattga caatcgatgc gaaggcacaa aaaacagctt ttgacagtct aggaggaaaa
    16921 gctggatcaa ctgttgcgac aacgccaaaa accggtgatc ttcttgcgct tgctagctct
    16981 ccaagctatg atccaaacaa aatgacaaac gggatctcac aagaagatta caaagcttat
    17041 gaagaaaatc ctgaacatcc attcatcagc cgatttgcga caggttatgc tcctggatct
    17101 acgtttaaaa tgattacagc agcaatcggt ctcgacaacg gcactatcga tccaaatgaa
    17161 gtgttgacga tcaacgggct taaatggcaa aaagacagtt cttggggatc ttatcaagta
    17221 acgcgtgtca gtagtgatgt atcacaagta gacttaaaaa ctgctttgat ctattccgat
    17281 aatatatatg cggcacaaga aacgttgaaa atgggtgaga aaaaaattcg tacaggctta
    17341 gataaattca tttttggtga agaccttgat ttgccaatta gtatgaatcc agcacaaatt
    17401 tctaatgaag atagctttaa ctcagatatc ttgctagctg atactggata tggacagggc
    17461 gaacttctaa ttactcctat ccagcaagca gcaatgtatt ctgtttttac caacaatggc
    17521 acacttgtct atcctaaatt gattgcagat aaagagacaa aagataagaa gaatgtcatc
    17581 agcgaaacag cagtacaaac gatcgtgcca gatctgagag aagttgtgca agatgtaaat
    17641 ggtacagcac attctctttc tgctttaggg attccgttgg cagcgaaaac tggtacagcg
    17701 gaaatcaaag aaaaacagga tgtaaagggg caagagaaca gtttcttgtt tgctttcaat
    17761 cttgataacc aaggttatat gatggtcagc atgttggaaa ataaagaaga tgatgattca
    17821 gcaaccaaac gagcatcgga actattgcaa tacctcaacc aaaattatca ataaaaaatt
    17881 gctttttaag tacagtaaaa ggactgtggc gttatcgtca cagtcctttt ttcaaataaa
    17941 cggttttcac gatgtctctt tcacaacttc tttttgattt actcacactt cataaacttt
    18001 ttttgtaaaa tatttgagaa caagtggaga aataagtgta cttaataaaa tcacgataac
    18061 taaaggtgaa tagtactgtg gttcgatcaa ttgactttgc tgtccaattt gtaaaatgat
    18121 caaagccatt tctccacgcg aaatcatacc agcaccgacc atcaatgaac tatgttgaga
    18181 aaaaccggca atctgagcac caaaataacc tccaagcaat ttggtcaaaa tcgctacaag
    18241 cgtcaatata gaaataaaga gtagttgttc actaaagtca gaaaaatcaa cttctaatcc
    18301 tacactgaca aaaaatactg gtataaatac tgcatatcct aaagcctcta cattgtggta
    18361 tacttcttct ttaacctttg tctgactgac agctatccca gcaaaaaaag caccaatgac
    18421 agagctaagc ccaacaagat ccgctacgta agacattcct aaacaaataa ctagcgatac
    18481 gatgataata gaagaatttg cgtacacttt ttctgcaaat gaaagtagga aaggcgcaat
    18541 ccatttgact aataagaaaa taaaaacaaa ataaattagc tgttcaatca aaacaagcgg
    18601 taaagaagca ttgctagaag cttcccccgt tagaaaagat aggctgaaac ttagaactaa
    18661 aacgactaaa atgtcatcta ccacagaagc acccaaaatt gttgatcctt cttttgtatt
    18721 cactacgttt agttctttta atacttctac tgaaatactg acagaagttg ccgcaagaat
    18781 aatcccaaag aaaatcgctt catttcccga aacttggaat gctttgcctg tcaaccagcc
    18841 aaaaacaacc gggaagatga tcccaagcaa agcaacgaac ataccaggtc ggaaatattt
    18901 tttcaaaaga gataaatcac tttccagacc agctaaaaac attaataaga tcacaccaat
    18961 ctccgaaaag tcatggacta gaatatcagg tttgacccaa ttcaatccag cttggcctag
    19021 caaaacacca acaagtaatt gtccaatcac tgctgggata cctaatctcc gcgagatatg
    19081 tgagccaatc gttgttgaaa tcaatatcag gcataaaata ccaataaatt ccattctcat
    19141 cattcctttg tataaaatat agcccgaact tagcataaca tacattattg aaaaaatagg
    19201 aaaatatact cacaaaaaaa ccaacaatcc aaaagatttt tttggattgt tggtttttat
    19261 acggtctatt ttaataacta aaaatgatta acgtatagtc atttttctta ttctgatgaa
    19321 attgataatc tcctggatgc ccatgaaaat caaaataaag ccgaatattt ggaatagaag
    19381 catcaaactt ttgaatggat tgaacaataa gacgaatccg ccaatcaaca acagaatact
    19441 actataaaca ctccaacttt tagcttttgt attcatgctg aagaacaact ggaacaagct
    19501 gttgatgata acagctaatc caagaagaat cggcaggata gaaacgattg caggtgcaaa
    19561 agcatagacg atcagagcta agatcaggaa aaaaagacca ctgaacagac cgatactcca
    19621 agaacctgtt ttccttttaa aacggtaagc ctcaaaaaga ttcaacaacc caagcaaaac
    19681 aagataggcg gtgatcagat aaccgataaa atgaaaaaca gcagaagggt ttagcacaat
    19741 cgcaatccca gaaataatat aaacagcagc tcttaataag gcgtattttt gaatattttg
    19801 tttaatcgtc tcaaacatat aagaaaacct cctttgactt attttaacgt gaactagtca
    19861 ttttaccaaa ttaaatgtta caaaatgagc gaaggagaag aatatctctg gaaaaatcaa
    19921 cttctgagga tcttttccat ttttttgcct tttgctagct catcgatcat tttatctaaa
    19981 taacgaattt ctttcatcaa gttatcctcg atgtcttcta ctcgtacacc acaaacaaca
    20041 cctgtaatca aggaacgtga aggattgggg acaggggctt ccgcaaaaaa ttgttcgaaa
    20101 gtcacttgtt tttgtagttg atattctagt tctgtttggg aataacccgt cagccaacaa
    20161 atgatttcat ctacttcctc ttttatacga tcttttctct ccgcttttgc tacatacata
    20221 ggataaacgc ttgcaaaact tgtcgtaaaa atacgatttt gcgccataat cagtcacctt
    20281 tctttttttc aaattattta ctacttatag tatataagaa aaagagaaga aaaagcgatt
    20341 attcaaaaaa acaaaaagga ttgtgacaaa attcttgtca ccatcctttt ttccgctctc
    20401 tgacttttta caatcttcat agctcaagtg cgcatcagat aatcgaatgc tcctaaagct
    20461 gcagtagctc ctgaacccat tgaaacaatg atttgtttgt atggactatc tgtacaatca
    20521 ccagctgcga aaacgccggg gatattcgtt gcgccatttt tctcggtcac tatttcattt
    20581 cttggattca tttcgatcgt tccatctagc caatccgtat tagggagtaa gccgactaga
    20641 atgaatactc ctgaaacagc tagtgtatgc atctccatcg tacggcgatc gatataggag
    20701 agagattcta cctgattcgt accgctgatt tctttcgtcg ctgcatgttt gataacagtg
    20761 acattcgcaa gagagactag tttatcctgt aagatttgat ctgcttttaa ttctggtaag
    20821 aattctagaa catatacatg ttttgctaac ccagccaaat cgattgctgc ttcaacacca
    20881 gaattaccac caccgataac agcaatctct tttcctttaa ataaagggcc gtcacagtgt
    20941 gggcaataag caattccttt atttttaaac tctttttcgc ctggtacatt gatagaacgc
    21001 cagtgcgcac ctgtcgcgat gatggcggtt tttgctttaa gtgatatacc gttagctaag
    21061 ccaatattaa taaaatgttg ctctttattt aaggaaacgg cctgttgatt catcataatg
    21121 tcgatagggt aactacgcac atgactttct acttgctgca tcaattttgg accttctgtg
    21181 taagaggtac caatcatatt ttcaatccct agtgtttcaa cgacttgtcc gccgaaagaa
    21241 tcagcgacaa gtcctgtacg gattccttta cgtgctgcat agatagctgc actactagct
    21301 gctggtccac cgccaatcac taatacatca taaggttctt tttcaaacaa ctcttcttca
    21361 atcaaagggc cagtgatttt ttcaacaatt tgttcgatcg tcatgcgtcc gctactaaat
    21421 tcttctccat ttaaaaacac agttggcact gccatgattt ttttatcatc gatttctttt
    21481 tggaacatcc caccttcaat catcgtatga gtaatatttg gatttaatac agctaatata
    21541 ttcaatgcct gtacaacgtc ggggcaatta tgacaagtca agctaacata actgtcaaaa
    21601 tgcaatgttt gtgttatttt tttgatttta agactcaaag attcactgat tttcggtgcc
    21661 cgtccactaa tttgtaacat agccagtaaa aaagaggaaa attcatgacc gagggggata
    21721 ccagcaaaaa cgattccact ttctttgcca actggattga tagaaaaact aggtgtgcgc
    21781 atcgaatctc ttttttccca agagatttta ggagacattt ctgctatttc cttcgtaaat
    21841 tcagctagtt tttgactatt ttcactatta tccaaactaa cagaaaaaac aataggagat
    21901 tcaatcagtg ctaaatattg ttcgagattt tgtttagttt ctttgtctaa catatccacc
    21961 acctaaatct ttccaacaag atcaaaactt ggtttcaatg tttcgccact ttctttccat
    22021 tttgccggac aaacttcacc tgggtgggta cgtacatatt gagcagcgcg aatcttatca
    22081 atcagtgcac tagcgtcacg accgattcca tctgcattga tttccatagc ttgaacgatt
    22141 ccgtctggat caataataaa tgttcctcgc tgagctaatc cttgctcttc atccaaaaca
    22201 tcaaaaatac gagaaatctg atgagacgga tcaccgatca tcacgtattc gattttaccg
    22261 atagcatctg atgtatcatg ccatgctttg tgagtaaagt gggtatcggt agagcaagaa
    22321 aagacttcaa cacctaaaga tttcaatgta ctgtattgtt cttgtaagtc ttctaattca
    22381 gtaggacaaa caaaagtaaa atcagctgga tagaagcaaa gaatactcca gttccccata
    22441 agatcttttt cactgacttc taaaaattct ccttgatgat aagcatgtgc attaaattct
    22501 tcgatttttt tcccaatcaa tgacatagta aaacctccaa taataattat ttatttataa
    22561 ttattgtaat ttagttggag ttgcaaagtc aatggatatt ttgttattta ataaagatta
    22621 ctcaaaaacg aaggttaatt ataaaaatag aagaggtcgc aagaaaatgc tactgctgga
    22681 aatactcggg ataacgttga gtaacagttt cctgttcttt cagcatcatg tgtaagtgca
    22741 atcccgtttg aaatcgagct tcttctggtt ttttatcaac taaagccttg agtaaatcat
    22801 aatgttgttc catgatcgtt tcccatggaa gcccctgaat ggtcactcgt aaccagcgga
    22861 aacgttctaa atgggtatta tggtcatcta accagttcca aacttctttt cttcctgcaa
    22921 tttcgaaaca agcttcatga aataaattat ctgcacggaa aaaagcgcgt tcgtcattta
    22981 ttttgactgc tttttcttgt tcttctaaaa tcgtttctag cactattcgt gtttgtgtgt
    23041 ccaatttgga acaacattca atcatgattt gctcttccaa ctgttctcgg acaaagcgag
    23101 cattttctgc agaaacaaga ttaattttgg aaacatacgt accactttga ggtatcgtat
    23161 acacgagttc ttgctgacgt agttgaatca atgcttcgcg aatgggagtc cggccgatag
    23221 caagatgttc ctccagtgcc ttttcagata ttttccttcc aggttctaag tcagcataga
    23281 taatttgttt acgaatcgct tgataagctt gtgattgcaa gctgcttttc atctttattc
    23341 ctccaaaatc atttctatga acgtagtata acagaagagg tctgaaaaac aatctggtat
    23401 gtcacattaa ctagtaaatt tgtataaata gtaaaatttt ggttgacata gcgattttta
    23461 ttgcataaaa ttcacttgaa tacaaaaact aatatgttag tttaggaggg gaaaaatgat
    23521 tgatttaaac aactggagga actttatccc tgaattatct caaaaagaag tagaaatacc
    23581 tcattttgac cgtgcatcat taagagaaaa tggacaaaaa aatcctgtct ggatccattt
    23641 cggtggcgga aatctttatc gaggatttca tgcagaaatc gctcaacgtt tagcggatct
    23701 aggcgaattg tccactggtg tcattgtttg tgaaacattc gatgaagaaa taattgaaag
    23761 ggcttaccaa gattttgatg atttgattct tgaagtggtc atgccaagca gtggagagtt
    23821 cgtcaaacgt atattagctg cgacagctga cagtctgtat tgtcatccag attgttctga
    23881 acactttgat aagatgattc gacactttga aaatcctagt ttacaattag ttacttttgc
    23941 tattactgaa aaaggttatc gattgaaaga tacaaataat aaatatatag gaccgattgc
    24001 agtcgatata aaaaatggtc caaagaagcc atcacataca atgagtattc ttgctgtgct
    24061 actttataaa cgttttttat ctggagcttg gccgattgca cttgtctcta cagataattt
    24121 ttcacaaaac ggtagtcaat tacgtacttc tttgctaacg atcgcaaaag aatggcaaaa
    24181 ggaaggttat gtacaaaata catttatcca atacttatcg aatgaagaaa ttgttgcgtt
    24241 tccatggacg atgattgatc gtatcacccc gaatccttcc ttgtcagtta gcaaaatgtt
    24301 ggcaaaagag ggcttttcaa atatgtcgat tttccaaacc gcaaaaggaa ataatattgc
    24361 tccatttgtc aatacagagg acatccatta tttaatcatg gaagatcatt ttcccaatgg
    24421 acgtccgaaa ttcgaaaaag ctggggtatt cttgactgat cgtgcaacgg tagataaagc
    24481 agatacgatg aaggtgacga cttgccttaa tcctttgcat acgtctttag ctattatggg
    24541 ttgtttactg gggtatagga gcatagctga ggagatgaaa gatccagatt tatcgctgct
    24601 agtttctgaa atcgggtaca atgaaggcct cccagttgtg gagtctccag gtatcattga
    24661 tccaaagatc tttctggaag aagtaattac tgtgcgcttt tctaatccaa atattcctaa
    24721 tatgcctcag cgaatcgcca cggatacctc tcaaaaggtg gcgattcgtt atggtgagac
    24781 gattaaaaaa tatatggaaa tagaagttaa agacccgcag acacttgtat tcataccatt
    24841 gactctcgct gcttggcttc gataccttat tggcattgat gatcaaggaa aaccattcat
    24901 cccgagtcca gacccactat tgacagacct tcagcataag ctttccgata ttcaactggg
    24961 tacgcaagat acatcacata ttcatgagaa aatggctcct attttgtcaa ataaagaaat
    25021 ttttggtgta gatctttacc aagcagagct tggcagaaaa atagaagaaa tgttcatcaa
    25081 gatggtagca ggaccaaatg ccgtacgaaa aacattacag gattacttac aagaacatgg
    25141 aggaaattta tcatggaaat gacttttaga tggtacggat cacaggaaga aaagattacc
    25201 ttagatgaaa tcagacagat tcctgcggtc aaagggattg taggcacatt gatggatata
    25261 ccagtaggag aggtatggcc tagggagagg atcaaagaac taaaagaaga aattgagtct
    25321 cgtgggttaa cactaaaagt aattgaaagc gtcaatgtgc atgatgccat taaaattgga
    25381 ttaccttccc gtgagcagta tatcgaaaac tataagcaga caatccgaaa cttggcagaa
    25441 tatggaatag aagtcatctg ctataatttt atgcctgtat ttgactgggt gaaatctgac
    25501 cttgactacc gcttagaaga cggctcatcc acgttagctt ttatatctga tgatattcca
    25561 gatgatccaa gagaaatcgt cgcgcgcatc gaacattcca gcaatgaatt tggattgccg
    25621 ggatgggaac ctgagcgctt agctcctatc aaatccttgc ttgaagccta tgcatcagta
    25681 gacgaagaaa aacttcgaga aaattttgcc tattttctcc aatcaatcat cccaacatgt
    25741 gaagaggtag gggtcaaaat ggctgtacat ccagatgatc cgccatactc gatttttgga
    25801 ttagctcgaa tcgtaaagaa tcgagaagat ttagattggt tgtgtcgcat agtagacagc
    25861 ccttataacg gaatcactct ttgtacaggg agtattgcag aagatccaga aaatgatgta
    25921 tatgggattt tagcagaatt ttgccaaaga gatcgaatcc catttgcaca tgttcgaaat
    25981 attaaatttt tagctaatcg agatttctat gaggcaccac ataaatccga atacggttca
    26041 ttagacatgt accgcatact aaaaacaatg tatgacaacg gatttaacgg atacatccgt
    26101 cctgatcatg gaagaatgat ctggaatgag acaggaagac caggatacgg cttatatgat
    26161 cgagcattag gtgctgttta tctaaatgga ttatgggaag caatcgaaaa aggaaacaaa
    26221 agtaaagata attagtgaaa aaaactgtaa ttttattatg taaataagaa ggatgttcaa
    26281 attcttgata cataaatccg gaggttgtta ataagcattc ggatttatgt atcttatttg
    26341 gtctaggaag taacttgatt ttcttttttc gattgatcca tgagtgcttc ttcttttaat
    26401 tcaaagatat attctgagat cctcataatc acttttttcc agtcttctgg tgtgatgatt
    26461 ccttttaaaa tatagatttt tttgatatga gaaggcaatt gtttcaaagg gcagtcgctg
    26521 ataacgatgt tgcagttctc cataaaatca ttttgtattt tgatcgattc atttgaaaaa
    26581 atttgttcta tcttaacgat cagatcttta ctgatataaa aatcacgcgt atagttcaca
    26641 ccaatcacaa ttcgcggctg ttttttgtag cgatcataca aatgtactag gtcttcaacc
    26701 atccattgca cattttcctt ttctaaaata actggtaaca agtgttgatt ttgttctctg
    26761 aaatccatat aaaattgttc aatggcggtt tggacttctt tcaatacgct atgttcttga
    26821 taaagcatga aagtaggaag gggcgtattt ggttgattga agttaagaaa tccattataa
    26881 agtttatttc gtgcgaatgc caatgagtaa agaatctttt ctttttcagg tataaacaaa
    26941 tcaaatacag tacaaaggga ctccaccatt tctcttgaat aaagaacatg aggaacgttt
    27001 gcttttttta aaagtttgta ttgctccaag cttgtttctt ccgattcgat tttcgtgata
    27061 gaaagtcgag ctaaaatatt cactaagatg cgttgttcgc gacaaattgg cagattaggt
    27121 cgcaaaatat ctacagagag atcaataaaa aagtcaatat attcatactc tgtgaattct
    27181 ttttgtacgt ctttcacaga agttgcagga aaattctctt tacatatttt taatagaaaa
    27241 tataatttat ctatcatacc gctatttagt cggtcaagta cttctttttt aaaaaaagta
    27301 ttcatcataa aagccactac ttgcggatct tcatcataaa attctgtagc agtacttgaa
    27361 aagatgttcc aataaatatc taatgctgca tattgaattt gtacctcttt tccagaaaaa
    27421 gactttctgc cattattaga aaaggagata gacaaaccgt actatgctaa aaatgcatta
    27481 atctttttca ttttcgtata caaataagag gcactatagt ttgtttgctg actgaaactg
    27541 ataatcgaat ttgtctgaca gctgaacaaa gaagtcaaga tctgataact gactgattcg
    27601 ttgcagtatc ttccaaatag acgataatag cagtaagccg gatcaattcc ttcaaaattc
    27661 aactttaaaa aaggtttttg cttatcaata tgcagttctg ttagattgag acgctcaaag
    27721 tcttgttcta attctttgat gtatagtaaa aaatttgatt cagacatatg gaaatgatct
    27781 gctaaatatt gtgtagtaat aaagaaacga tgttcagata ggaaaagaaa aatatctaat
    27841 tttgtattgc tttttttctt caagataaac gttttaatcg cttcttgagt ttgcatgaaa
    27901 gaggctcctt tttacttaaa ttgttaaaac ttgaaaatat tactgttttt ttcataaatt
    27961 tagacaaaaa aacagtaaac atataggtag aatctctact atcttatttc ttgcatacaa
    28021 aaaaatcaag gagtgagaga gttatgagat attcaaccat cttaatatca acatttgcag
    28081 ccttaagctt atcgcttact ataaatcaga cagtccacac agaggagaca gaaacagcca
    28141 aatggacaga aaccaagtgg gccaacgtca atcgaattac ctttcaggat gaattttcat
    28201 ccttcaattc aggagtcgca aaattaagaa aaggacaaac agcgaccatc aaagcaaaaa
    28261 ttgactattc gggagactta gcacctatac tacaatcagc tgttacattt gagaatgttg
    28321 atcccacttt gtcgattggc tatgacgaga acactttgac tatccaacac aagcaagcga
    28381 tatttacctt caccgttaca ttaaatcagg acttgttaaa accagcgctt tttactgtca
    28441 aggtatcaga tggactaccg aacgatcatc atttaacgcc gtatagtcag cggcagacaa
    28501 ttgagcaaga ttcagccatc gactcaggag gagatcttgt tgaagaacca acagataaac
    28561 cagaaaatga aaataagcca gaagtaccgc ctacagaaaa tccagacgga gaacagaaac
    28621 cggaaataga acctggagaa gaacccgata cagaaactca accagagcca gacaataaat
    28681 caaaacctga aataacccct ggagaaaaac cagatgtaac tccagaacca gatacggatt
    28741 ctggaaacca aacagtaccg gaaacaaatc cagacacaga taatgaaact gaaaatccag
    28801 aaaaaccaga ggtagatcca gaagaaaaac cagatgtgac tccagaacca gatacggacg
    28861 caagagacca aggaatacca gaaaaaataa acaaaaaaac aattcaagag gatggaaaaa
    28921 aagagagtaa aaaatcaaat ctagcaattc taaaaataaa tgaagagcag ctgaataaaa
    28981 aatcacgaat atttgatagc gcccaatcag ctgaaacctt aaaaagtagc aaggatacaa
    29041 cctttgctgt cctgaaacga aaaataaaca gctaccaaaa tccggagagt cacaaaacaa
    29101 agttatactg tggagcggaa tcattctatt aagtatagca acaatgcttt ctgcaaaaag
    29161 atttaaacaa aacagatctc tctaacattt gaataatgtc tgtgaacgca tttttcaaat
    29221 aaaaagaaat atccagaaaa tgaccccaaa ataccagatt gaaatctgat atttggggtc
    29281 gttcatactt tatctttctt catatttatt ttaagggata tctgtttctt ttggaagatg
    29341 gttcgggatc tttttcactt tcaatacatc taaaaagaag gtaaagatcg gaatgccgac
    29401 aatcaagccc caaacgccaa agaaccgttc gctaacaagt aagaccacaa atgtataaaa
    29461 aatcggcagt tctgttttgc tggacatcaa cttcggattc agcacataag actcaattag
    29521 atggacaatc aaaatcgtaa tcaggatata aacaacatct cggatgcctc cttgggaata
    29581 agctatgaaa gatagaggaa tacaagaaat gataacacct gctactggga tcagacttaa
    29641 aatgaaaatc atgatcgcta aactcagcag ctgatgaaag ccaaatacag ccaaggcgat
    29701 tgtagtgagc aacgtattta aaagagcgac aacaaattga gcttctaata ccaaaccaaa
    29761 tgtattgaca aacttatcgg caaaatagta aatatcttga aagaaccaag aaaattcact
    29821 ttttaaaaac aatcttgaga atacaattgt ttttttcttt tcaatcataa aaaagaaact
    29881 taagatgaat gacatagcaa acgccactgc catttttcct atatcctgta aatagccaag
    29941 cgcaatcgaa gcgccatttt gaagctgttc aaaaaaatcg tttcgctcaa tataagtatg
    30001 gatatattgt aaaacaggat ctgcatcttt tggctgatgc tcgtaaaaat taataacgga
    30061 ctggatcatg tcaaatgttt gatgaataag catcgggata tactttgtga atgccagata
    30121 gataaggtaa acgatcagtg tataaatcat gatagctaaa acacctgtag ggattcggac
    30181 aaatcgctga atgatttgaa caagatgaat catcaaataa gtaaagataa atgtgagcaa
    30241 aatggttgta atcatacttc taactaagaa aagaacaaaa acgacaaata ataaaacagt
    30301 gagacggcgt attttttcat tcgccaaaaa acgctgataa acggtcaaat cgacaacctc
    30361 caaataacaa aaaataaaca cgttattcat tatatgatgg aatatgaaaa taagaaagag
    30421 caaaaagaaa aaccgctaaa tgacgttatc ttatgagttg gttttcctca taaaatcgtt
    30481 catctagcag tttcagccct ttttctggtc ttgatgaaaa ttatctagca tttttcgggt
    30541 cagatgttgc agtgtatcca attcttcctg ttcaagtgga agataagact tgatcttttg
    30601 tggaatacct tctgcttgtt tttgcaacgc agcaccttga gcagtcagcg taacatttac
    30661 gattctttca tcacccgttt cacgctgacg attaatataa tttttttctg ctaacttttt
    30721 tagtaaggga gtcagcgtac cagaatccag acacaaatca tttcctagct ctttcactga
    30781 agtctttttc ttttcccata aaactaacat cacaagatac tgggtatagg taagattcag
    30841 cggcttgagg aggggagtgt agtgtctaat gatttcttta gaggcggcat ataaaggaaa
    30901 acatacttga ttaactaaat atagatcttc catttttcca cctccgctgt tttactatag
    30961 tgtatcatag cggatttaca caaaaaagtc tattcactaa ctgctttcag agtaacttct
    31021 atatttccag ctgtagcttt tgaatacgga cacactttat gcgctgcctc taataattct
    31081 tgcgtttctt ccagagaaag accttcgata gatccttcaa tctctacacc taagacaaag
    31141 ctcgtttcac tttctgaata aagggaaact tgtgcactga cagtagaagc cccagagata
    31201 tttttttgct gtttgatcaa ttctaatgca ctgttaaaac atgcactgaa accagctgca
    31261 aacaattgtt cagggttggt tgcattttcg acgcgtttac caggagctgc aatattcaat
    31321 tcgaatgtac gatcgggatt atgcacttct ccagagcgtc cgcctgtgtt gatcattttc
    31381 gtagaataca tttttttcat aaaattacca cctttaatta tattttatac aattgaattt
    31441 tacacaatat aattgtggaa agcaaagaaa tggattggca taagataaat aagagaaagc
    31501 acatgaaaca gacgcgcttt ctcgaatagc aaacatatac aaaaaatatc agagacaaaa
    31561 aataatctca tcataaacat tacatatatt tctcaaaaag ttgttttctt tcttcaaaaa
    31621 ttacttcacg atggacctga tgaagcatcc ataaataacc aaaaggatct ctgaacattg
    31681 agttagtcac accaaagtcc atcatttctg tcatttcttg aatctctaca cagccatttc
    31741 gtaatgcttt attatgtgtg tcctcgatat cagagacgat gatattgaac cagatcgtat
    31801 ttggatgttc agcagtagga gcagtcaaac caagagacgt gttttcatcc agcatatgga
    31861 atctcgtacc atacaaggta aaaatgactt cattattgcc tctagggtaa tctgttgcct
    31921 caatcagttg tatttcatca aagattgttt gatacagttc tagtgctttc aaactatcat
    31981 ttaatacaaa atcgatttcc gttcctttat gcataaagat ctcctctcct tttcagtcga
    32041 acagttacta gattctttta ttataccagc taaagaaaac gcattcaaaa aaatagcgga
    32101 tttacttacc aactcattcg attggatgat aagtaaatcc gcgtcccatt acttctgcta
    32161 cgctgctgac aatgacaaag gcacttggat cgatttcttc tatcaatggt ttcattcggg
    32221 aaaattcatg atcagtcaca acgatcaata aaacctcttt tgactttcga ttatacccgc
    32281 cttttgcctc tagcagggta aggccacgtc caatctcagc acttaagcga aggcggatgt
    32341 cttccaaata atgttcactc atgaccataa cagatttctt tcgattgata cctgtttcga
    32401 tataagtcat gacaattgaa gtgattgcaa tagataaaat agcataaaga aactcttcta
    32461 ttccaaaaat aaacagatta agagaaacaa cgaatgcgtc tgtaaaaaat aagccaatcg
    32521 aagtattcaa gtggaaatat tttttaaaaa tgaggggagg gatcgtcgta ccgccgctag
    32581 aagagttgtt tttatataaa atcgcaactc ctaaagcaaa aatcgcactt ccaaaaatga
    32641 cagacaacaa ccgatctgaa gtaatcattg tttctggaac tattgcaatg attaaaggaa
    32701 aaaccaagct tccgaaaagt actttaaaaa agggtttttt acctaaaaat agaagagcta
    32761 gtaccaacat aacgatattc aacactaaaa taactatagc tcggtcaaag cctaaagcag
    32821 cttccagtaa tattcctaga ccgctgacac ctccagcagc aatatgatga ggccctaaaa
    32881 acatattgat agcgactcct aatatgaaga gggcaaaaat aatcttaatg tatgtccata
    32941 taaattgtct cgtttctttc atttattcac ttccttaatt cattaataat actcttatct
    33001 tattataact tacttttcac cttaagttaa ctttaattaa taaaaaaatt aggctagtct
    33061 aaattattat gtttcattct tctagaatat acttctacgc caaaaactgt taaaaaactt
    33121 ttactttaga aaattggaga aattgatcgc ttaagataaa ttcaggacac taaatagtac
    33181 aggaagtaga ctaaaacttt taaaagtttt aagtctatct atttggcaag tttaa
//
LOCUS       DAFEEZ010000028        32300 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000028
VERSION     DAFEEZ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.028"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(126..1229)
                     /locus_tag="LP245_001388"
     CDS             complement(126..1229)
                     /locus_tag="LP245_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBL1519314.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(1451..1921)
                     /locus_tag="LP245_001389"
     CDS             complement(1451..1921)
                     /locus_tag="LP245_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBL1519315.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            2178..3497
                     /locus_tag="LP245_001390"
     CDS             2178..3497
                     /locus_tag="LP245_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HBL1519316.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            3938..5578
                     /locus_tag="LP245_001391"
     CDS             3938..5578
                     /locus_tag="LP245_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBL1519317.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            5732..7054
                     /locus_tag="LP245_001392"
     CDS             5732..7054
                     /locus_tag="LP245_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBL1519318.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(7116..7547)
                     /locus_tag="LP245_001393"
     CDS             complement(7116..7547)
                     /locus_tag="LP245_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1519319.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(7611..8447)
                     /locus_tag="LP245_001394"
     CDS             complement(7611..8447)
                     /locus_tag="LP245_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBL1519320.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(8637..8939)
                     /locus_tag="LP245_001395"
     CDS             complement(8637..8939)
                     /locus_tag="LP245_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBL1519321.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(8965..9396)
                     /gene="ruvX"
                     /locus_tag="LP245_001396"
     CDS             complement(8965..9396)
                     /gene="ruvX"
                     /locus_tag="LP245_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBL1519322.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(9393..9659)
                     /locus_tag="LP245_001397"
     CDS             complement(9393..9659)
                     /locus_tag="LP245_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBL1519323.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(9913..10638)
                     /locus_tag="LP245_001398"
     CDS             complement(9913..10638)
                     /locus_tag="LP245_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBL1519324.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(11004..11074)
                     /locus_tag="LP245_001399"
     tRNA            complement(11004..11074)
                     /locus_tag="LP245_001399"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11040..11042),aa:Gly,seq:ccc)
     gene            11191..11943
                     /locus_tag="LP245_001400"
     CDS             11191..11943
                     /locus_tag="LP245_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBL1519325.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            11959..12438
                     /locus_tag="LP245_001401"
     CDS             11959..12438
                     /locus_tag="LP245_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBL1519326.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(12689..14269)
                     /locus_tag="LP245_001402"
     CDS             complement(12689..14269)
                     /locus_tag="LP245_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBL1519327.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(14262..15005)
                     /locus_tag="LP245_001403"
     CDS             complement(14262..15005)
                     /locus_tag="LP245_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519328.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(15181..15957)
                     /locus_tag="LP245_001404"
     CDS             complement(15181..15957)
                     /locus_tag="LP245_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1519329.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(16205..17041)
                     /locus_tag="LP245_001405"
     CDS             complement(16205..17041)
                     /locus_tag="LP245_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBL1519330.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(17052..17981)
                     /locus_tag="LP245_001406"
     CDS             complement(17052..17981)
                     /locus_tag="LP245_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBL1519331.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            18173..18526
                     /locus_tag="LP245_001407"
     CDS             18173..18526
                     /locus_tag="LP245_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBL1519332.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(18600..19256)
                     /locus_tag="LP245_001408"
     CDS             complement(18600..19256)
                     /locus_tag="LP245_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBL1519333.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            19482..21416
                     /locus_tag="LP245_001409"
     CDS             19482..21416
                     /locus_tag="LP245_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL1519334.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(21502..22725)
                     /locus_tag="LP245_001410"
     CDS             complement(21502..22725)
                     /locus_tag="LP245_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL1519335.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(22719..24617)
                     /locus_tag="LP245_001411"
     CDS             complement(22719..24617)
                     /locus_tag="LP245_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBL1519336.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(24611..25729)
                     /locus_tag="LP245_001412"
     CDS             complement(24611..25729)
                     /locus_tag="LP245_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL1519337.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(25812..26645)
                     /locus_tag="LP245_001413"
     CDS             complement(25812..26645)
                     /locus_tag="LP245_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1519338.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(26638..27555)
                     /locus_tag="LP245_001414"
     CDS             complement(26638..27555)
                     /locus_tag="LP245_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL1519339.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(27782..28906)
                     /locus_tag="LP245_001415"
     CDS             complement(27782..28906)
                     /locus_tag="LP245_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL1519340.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            29089..29997
                     /locus_tag="LP245_001416"
     CDS             29089..29997
                     /locus_tag="LP245_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1519341.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            30138..31751
                     /locus_tag="LP245_001417"
     CDS             30138..31751
                     /locus_tag="LP245_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1519342.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT         9977 a         6412 c         5502 g        10409 t
ORIGIN      
        1 agtatgaaaa aatatttcaa ttttattttt tcgtttcaaa ttattctatt agtgacatcc
       61 ttgaactata aaaataggag tacggcatca tctgccgcac tcctattttt ttcgtcattt
      121 gtttcttaaa taaaacgatt ctcacgcaat tttatttttt tgatatcttc tactgtttgt
      181 gttccagcta attgcatgac catttccaat tctgttttaa agaaatcaaa cacttgatgg
      241 actcctgtac ttcctcctaa agacaatcca taaataacgg gtctgccaat agcaacaaga
      301 tctgcacctg atgcgattgc tttgaaaaca tgctgtccgc gtcgtacacc gctgtcaaac
      361 acgattggta cacgtttatc tactgcttct gccacatatt gcaacgaatc aaacgctgct
      421 ggaccaccat ctagttgacg gccaccatga ttagataccc agattccgcc agcaccagat
      481 tctaatgaac gatagacatc ttcttctgac tggacacctt tcacatagac tggcaaatca
      541 gaatgagcag caataaattc tacatctttt ggactaagct tctgtttgga agatttgtac
      601 acagcatcca tcgtttggcc tactcctgat tgataagcct gaacgatcgg cattggcagt
      661 gggaaggtaa acccatttct gcggtctgtt tcacggtttc cgccaactgt tgcatccgct
      721 gtcaatacga ttgcttttgc tccattacgc ttggccactt caagaatatc caaattgatc
      781 ccatcatctt tgctcatata aaattgaaac cattgcggtg ctttctcccc gcctgcttct
      841 cttatctctt ctaatgtaca agaagcgtaa gaacttgctg tatagatcgt cccaaaatct
      901 gctacacctt ttgcagaagc tttctccgcc ttcacatgag ctaagccatg agcagcaact
      961 ggtgccatga tgattggtgc agtcagcgtt tctttgtcaa aatgtgtagt tgtatcgggt
     1021 aattctacat ctcttaatac atgaggaata atcagctgat gattgaatgc ccgttcattt
     1081 tcttgataag taaataagtc gccagcacca ctgctgatgt aaccataacc accagctgga
     1141 atcacttgtg aagcggctat ttctaaatct tccatattga taaaatccac tattccttca
     1201 tttgtacctg cttgatacgt tttttccatt tcaatgcctt ccctctataa aaaattgaat
     1261 gaataatatg atagcgttta cacactttat attactcttc cgtattgata caggcaaata
     1321 atctgtttac atttcagtca ttccagttgt tactactctg aaagaaatgt ttagaacaca
     1381 aatagataaa aaacgatggg attttgacaa aagtcgtgtc aaagtccctt ttacgaaata
     1441 ctgtggatgc ctattgaaat aagtgcgggt tgtttctttg tatttcaatc gtttcttgcc
     1501 attcttcgtt taattttgga ttaccgtttt cttccttgaa cgcataaggt cccaatccaa
     1561 aaagctcagt tagtatttga ttcacgattc catatagctc ggtgtgatcg gacacatgat
     1621 tattgaagat catctcatta tcaccacgtt tgaatctcac attcgggctc tcatgatgaa
     1681 cctctatgca gttttcccct ttttttaact gacggatttc tgaaaacatc tcataaatat
     1741 cttctccaat aaaaccttca gcaagcgcca gactgtccac aagaccgcct actgtcaact
     1801 cagagattat cgctttgttg gcaccaagct ttaatgtata gcttgttgct tctactacgc
     1861 cgcatgcatt gcaaccacct tctgatagtt cgctttttct gatcaattga acttctttca
     1921 ttttctgttc ctcctcttag ttttctactt atgtattttt tatcacctga cgtaagtgta
     1981 ttttatcgtc acgatcacgt gatttattct tcagagattc tacctgaata attcatactt
     2041 ttaattaaaa ccatgtgaaa ctgcctcacg gcagcttaca attacttttt catcttcacc
     2101 cgttaagtga tgaaaaaaga acccctttct gctatggtta aagtgactaa accaaccaaa
     2161 agaaaggagt tcttttcatg actagcttac acaaaaacca agtaaaattc aattcaaata
     2221 tcactatttc tcatacaggt ggtcaattat cgagtgattc gggtctcgtc ctagtgaaag
     2281 agctgatgaa catctttggt ttttctgaac tggctaagca acacattcac attgaagacg
     2341 aacgagcgta ttttactcat gacaacttat ccatacttga gcagttcatt atgcaattaa
     2401 ttgctggtta ctcagctgat tctgcagcta atctcctgag acaagatcct gtgtttaaag
     2461 ctgttttaga taggaaagaa ctcgcttctc aatcttcact ttcccgattt ttagatcgac
     2521 tatctgagga gaatatccat gaacttcaag ctttgaacca agaacttatc gataaagcac
     2581 gcctcatccg taatgatacg gaattaatca ttgatttaga ttcgacccat tcagatacat
     2641 ttggtcacca agaacaaacg aattataata cacactacca aacctatggt taccatccat
     2701 tggtagcttt tgacggattg actggtgact tcttaaaagc tgaactacgt tcaggaaatc
     2761 aatatacatc aaaaggcgta aaggagtttc tcacaccttt attagagcac tataatcact
     2821 ctctaccaaa cactgacatc ttggttcgtg gagacagcgg gttcgctaca cctggtgtgt
     2881 atgattcgtg tgaatcaaaa aagagtcatt atgttattcg actgaagaat aatcgtagac
     2941 taggtcaaat agctgagaaa tcagtacttt atggcgataa tcaaaagtgg gaagaacgag
     3001 aagttcagta cttctcgacc acttatcaag cacaatcctg gtcacaaagt cgtcgcgtgt
     3061 gtatacgctc aacacgtgaa gcgggcgaac tactctttcg acatgaattt atcgtgacga
     3121 atctatcaga aaatgtttct cctgatacca tcttttctat ctatgccaaa cgtggcacaa
     3181 tggagaactt cattaaagaa gcgaaagctg gcttttactt tgacaaaaca gacagtcctc
     3241 gctttttgga gaatcatgtc cgaatgatgc tcagcttgat agcttacaac ttagtcaact
     3301 tcttaagaac gattggcttt gaagaagtcc aaaagggaat gaccattcat tctattcgat
     3361 tgaagtttct gaaagttgct gggaaattag tccaaacggg tagacgagtc tatctcaaat
     3421 tatctagtta tcatgtgtat cagaatgaat tctacagggt ctttgctcgc ctgaggcgag
     3481 ccagtcaatg gatctaatcc aacaatctaa cgattttttt actgggaagt tatccaggga
     3541 gaagtatgct caaaatgcct tacacccaaa atttattcct caatattttt gaacagtgaa
     3601 tgtttgaagt aactttttag tcaaaatcag ttgataggga tattagtgat acatatttca
     3661 ataaaatgtg ccaaagaatt aaagctatga attattcagg attctattta tctatctaac
     3721 atatccttta ttcttctact tttctttctt tagcatataa gagatacgca tagtaatcaa
     3781 gcaaggattg ttgatataaa aagaacaaat accgctattt tgatttcttt tgactctatt
     3841 actcatataa ataaaattta ttatacctgc tctttttgac tatatcctca tctgactcct
     3901 atacttcgtt tgtattaaaa cttaggagga atcattcatg cttacagggc taaacttatt
     3961 aaataatcct tttctaaata aaggaacagc ttttacaaaa gaagaacggg caaaatacgg
     4021 aatcactggt atgcttccaa gtactgtcca aacattggaa caacaatctg tccaagctta
     4081 cggtcaatac ttaagcaaac agaccgattt ggaaaaacgt atcttcttaa tgaatctatt
     4141 caatacgaac cggacattgt tttataaatt gatgggcgaa catttagttg aattcatgcc
     4201 tgtcgtttat gatcctgtcg ttgcggattc aatcgaacaa tacaacgaaa ttttcttgaa
     4261 accacaagat gctgtatttc tttcaatcga cgaaccagaa aatatcaaag caagtttgaa
     4321 aaacgcagca gatggacgcg acattcgttt gatcgttgtg acagatgcag aaggaatctt
     4381 aggtatgggt gactggggtg tgaacggtgt tgacatcgct atcggtaaat tgatggtcta
     4441 cactgccgcg gctggtatca atcctgcaca agtcttgcct gtatcaatcg acgctggtac
     4501 taataacgaa gaattattga ataatccatt atacttaggg aatcgtcatg ctcgtgtaga
     4561 aggcgaaact tactacgaat tcattgatca attcgttcaa tcagctactg aattattccc
     4621 agaattgtta ttacattggg aagattttgg acgaggaaat gctgcaacga tcttagaaaa
     4681 atacgaagat aaaatcacta ctttcaatga tgatatccaa ggcacaggaa tcgttgtact
     4741 agctggtgta ttaggtggat tgaatatatc aggtgagcaa ttgaaagatc aaacgatctt
     4801 gacatttggt gctggtactg ctggtgtagg tatcgcaaac atccttttag atgaaatgat
     4861 ccgtcaaggt gtacctgaag aagaagcacg ccaacatttc tatcaagtag ataaacaggg
     4921 tttattgttt gaagatacaa aaggattgac tcctggtcaa atcccattcg ctcgtaaacg
     4981 ctcagaattc actaatgctg atgaattgac aaacttagaa gcagttgtaa aagcaatcca
     5041 tccaacgatc atgatcggta cttctaccca acctggagca ttcactgaag aaatcgtgaa
     5101 agaaatggcg gctcataccc cacgtccaat catcatgcct ttgtctaatc caacaaaatt
     5161 ggcagaagca aaagcaaaag atttgattga atggacggac ggaaaagctt tagttggaac
     5221 aggtatccct gctgctgatg tggaatataa cggtgtaact taccaaatcg gtcaagcaaa
     5281 taatgcgttg atgtacccag gtttagggct tggtttgatt gcttcaacag ctacacgagt
     5341 aaatgctgaa atcatttctc aagctagtcg agcattaggc ggaatcgttg atgtaacaaa
     5401 accaggagca gctatcttgc ctccagtagc aaaaatcact gaattctctc aaacgattgc
     5461 tgaaactgtc gcaaaatcag ttgttgcaca aaaattgaat cgtgaagaaa tcacggatat
     5521 caaagaagct gttgaatctg ctaaatgggt tcctgaatat aaatctttag aagattaaga
     5581 ttgttatagt aaaagaacat acagaaactt tgtatgacgt ctaaaaagaa aaaagcgact
     5641 gcggcaaaac agcagccagc caactactgc tcttttgccg cttctctttg gcttttttca
     5701 tacgatacag aataagaaag gatctgtaaa aatggcacaa aaaacaacaa ccgcaactgc
     5761 agttgaggaa aagaaaaaag aagggttttg gtcaacaaaa attaccggcg taagtttgcc
     5821 cctttatttg atcatggtcc ttgtcctgat cattgcaatg gctttaggaa aattaccgac
     5881 gaatatgatt ggcccaatcg ctgttttggt cattttcggt aatttatttc attttatcgg
     5941 aacaaaaatc cctatagtca aaagttattt aggtggtggc tccgtttttg cgatctttgc
     6001 ctctgccgcg attgctacat ttgggatctt acctgagtat gtagtaaaat ccacagaaaa
     6061 ctttgtcagc aatatgggct ttttagactt ttatattgct gccttgatta ctggtagcat
     6121 ccttggtatg aaccgtaatc tattgatgaa agcttctgtt cgttttattc ccgttgcact
     6181 tatttcaatg gtcgtctcct tttttgccgt aggactcgta ggtatgctta tcggaaatgg
     6241 ttttgcaaat tccgttttat atatctcatt gcccgcaatg gctggtggtg ttggagccgg
     6301 agctgtacct ttatcaacga tttatgcaaa tgttttaggt acggacgctt cttctatcat
     6361 ttcccgcctg attcctgcga cagcaatgac aaatgtccta gctatcattg gtgcagcgtt
     6421 agttgctcgt gcgggacaat caatgccaaa attcaacggt aatggtaaat taatggaaaa
     6481 aggcgacctt ggcgatggaa aacctagaaa tgtaaaacct tccattccac aattaggtgt
     6541 cggtttgatg gtatcattga ctttcttcat cttaggacaa atctgtaact attttgttcc
     6601 taaagtccat gcttacgcat tcatgatcat tatcgttgtt atctgtaaaa tcgcaaacct
     6661 attaccagaa tattacgaag atgcagctat catgttcaac aacttgattg tcaaaaactt
     6721 gacagcagct gttcttgccg gtatcggtat tgcgttattg aatctaaatg tattggcttc
     6781 tgctttgaca tggcaatttg ttgtcttatg tttgacaagt gttatcgcga tttcagtagt
     6841 ttcaggattt gtcggtcgtt tgtttggttt atatccaatc gaatcaacta ttactgctgg
     6901 cttatgcaac aactcgatgg gtggtacagg aaatgtagct gtcttatctg cagctaatcg
     6961 gatggaactt attgcttttg ctcaaatggg caatcggctt ggtggtgcca tcgttttgat
     7021 catctcaggt ttcttgatgc aattactttc ttagtcaaaa aaaatacctg atcatcaagt
     7081 atcggcttga tgaccaggta ttttttgata aaaatttaca ggattttcaa aaatcttttt
     7141 tgcattttat cggaatgata accgatgcgt tcataaaatc ggtgtgcttc tactctgtat
     7201 tctgcagaat taagtcttat tgctgatatt cctcgtcttt tcgcttcttc tacgccagtc
     7261 atcaaggcct ttccgattcc tcttttttca gcatgtttag acacagcaag tgccataata
     7321 ttgaacatcg gatcgctgaa aatcgattca taggactccg cttgtacata gccagctgct
     7381 tttttagaag taggatcttc atagaccaag aaaaaatttt tttctggctc cttcaacagt
     7441 ttcttcattt gtctcaccgt aacggttaat ggtacatcat atcctaattg ttccgcattg
     7501 atttctcgta gtgcttctgc atctcctaaa cgcatttccc gcaacatcca aatcaccagc
     7561 caatttttat ttttttaaat gaattttttt atcacagtat actccttttt tcacttaaaa
     7621 aaagactttt cagtgatttt gacttgcttg aatccagatc cttctaatgt ttgcaagatg
     7681 acgaaagcat tgtaaagatt gatcaaaaga accacgatga caatcgcttg aaaaataaag
     7741 gtcacttttt ttggagacaa aaccctgcta aatcttgctc cccacaaacc tccaataaca
     7801 gcagcgggga taacataaaa caacatagat aaatcaaagc gcataaagct acttgttaaa
     7861 gcaatcgtta ccaattttgc cagttgagaa aagaaaatcg tagatagaga atatagtgtt
     7921 gcttctttta ttggcaatgc aaacatcagc atcaacaaag aaacattgac tggtccacca
     7981 ccaataccta aaaaactagc taaaaagccc agaacccccc cacatataag gtaccaagtc
     8041 catgacgtca aatgaaattt tggctgatga tgcttggtgt agaagaacgc aaaaaccaag
     8101 gtcaataccg tcaaaaaaat ttggatcagc tgcacatgct tctcgttttc aaataactgt
     8161 aaaaaaactt cgaatacaat gttgccgact actcctccaa caacagctcc actagatacc
     8221 caaccgacaa tctgccaatt cagtgatttc ccgcttgata cttgtcgcac agtcgaaaca
     8281 atggacatcg tgaataccgc aactgttgag taaaaagaaa tccctgcaac agaatgggcg
     8341 ccgataagat caagaatcgg tttgatcaac acgcctccac ccatcccgga aatagcgcca
     8401 actgtgttcg ccagaacgat caccacaaaa taaatcagac caatcatctt gtatttcctt
     8461 tctcttgttt atatctttta gcgattgtta ctcttttctt ttattataca gtaaaagaaa
     8521 caaacgaggc ttcgaaagct tttctacttt ttaaggaaat ttagtgctaa acgaaaaaac
     8581 cgggctctac ttttcagaga gtccagcttt tcttacacct tatcgattct tttgttctat
     8641 tcttcttccg ccatgaatgt attgaatact tcttcgatca tatcccattc tgcgtctgtt
     8701 tcgatttgtt ctaactcgcc ttctgttcca tcttcgtttt cgatgtatgc ataagcttgt
     8761 aattctacat cttcatcttc tgaaacacca gctggatata aaagaacata gttacgtcca
     8821 aattcttctt gtccgtcaac tgttagcaag atttcgtata atgtttcatt tccttggtca
     8881 tccaccaatg tgatgtgttc gtgtccttcg tgttcgtggg aatggttatg ttctgtcata
     8941 agattacctc ttttcttttt attattaaaa taattgctta cctgagccgt ctaaataatt
     9001 ttgtaaaatc atcacagctg ctaatttatc gatgactttt tttcgtttcg ctcttgaagt
     9061 atttgcctgc tctactagca tacgttctgc ctgaacagtg gttagtcgtt catcttgata
     9121 atcaaccggc aaggagaata gttctttgat cttctctcca tatgacatgg aagcttctgc
     9181 ccttggtccg atggaattgt tcatattctt aggtaatcca actacaaaac ggtctacttc
     9241 gtactgcgcc actaattcct tcaaccgatc aaaaccaaac tcttcttctg cctcattgat
     9301 tcgaatgatt tctactcctt gagctgtcca gccaaaggga tcgctcacag caacgcctac
     9361 tgtcttagaa ccgacatcca agcccattac tctcataaat tcactccatg atttgagagg
     9421 tagtctttga caattacttc catgatttca tcgcgttcgt gacggcgaat caaatttcgt
     9481 gcatcacgat aacgaggaat gtaggccggg tctccagaaa gcaagtagcc gacaatctga
     9541 ttgattggat tgtagccttt ttcttccaaa gcccgataaa caatcgctaa tgtttcgctc
     9601 acttcttttt tgcgactatc gtcaaaacca aaacgtacgg tttcatctgt aaaacccatg
     9661 attctacacc tctttcccgc aaggtaattc cagcttacct tctacaccct tattttactc
     9721 gaagaaaggg aaaactacaa acaaatattc caaacttctg aataaattaa gaaacacgat
     9781 ttgtctgatt tttccttttt tctgtggctt tttcaaaagc cctctttcca taaagtatac
     9841 gctatatttc tttgaaagta tgtttttaca caattttttc ataaagttca taaaaaattc
     9901 gaattgctgc tactaatttt tcgttttcgt tgcttgccct gtctcataat tgatggtgta
     9961 gccatcttga acattgtaga taaagacatt gaattcaatt tttttgtctt caatgctttc
    10021 tgcttccaac tgcacacctc ttgctaccag ttcatttccc tcgaaatgag gagtgacacg
    10081 atagcgtaca tgatgatttg tttccttgat atatgccgca atatcatttt cgtgggcaag
    10141 catgtacgga gcattcaacg aacgtgtccc tgtcattaag tttttaatgt tattattttg
    10201 accagtcaac tggaaaccaa tcaaatggct gcggttgtat aaccattgtc cgtcacttaa
    10261 tttcttttgt ttccaacctg tcggatcaat atacaaaggt tctctctttt cagtaggaaa
    10321 caagtctttt cccaacatcg cattggcttg tcctactctg ttcaatttgt ctatatttga
    10381 atagctttcc catgtccctt tggaaagact aagatcctct tttgtaaact ccggctgatt
    10441 cccattgatt tctatttctt gatgttttcc atcatattct ggcacatccg ctacttgaga
    10501 agcttgcggt gtggaatcaa aaatggttgt aatttgttgg aagatatctg aatctttttg
    10561 tgtggtggaa ataccgagtg cccctgcaat cacagcagcg acgatcccca cgatcgcctt
    10621 ggttgttttt ttgctcattt ctttactcct ttactaacag ttccctaaat cttaacatat
    10681 gttcccctat aaataaatac tggaaagaaa tagaaacagt aaaaaaataa aaccagtttt
    10741 tagacggctt aagaatacaa aaaaagagac ggattcatcg tctctactca atcacaaaac
    10801 actatttaca aggtatttat tatcattcaa aaaatttttc ttaatactca aaactaaacg
    10861 gcttctgtac gacctcttgg taaacagtgt tcaaaagctt gcatctgcgg taataagtcc
    10921 aaccaagtca aaaacataag aagctttttt gcttgactat tcttattact tgatgcaggg
    10981 cagctttttc acagcctctt ttaagcgggt gacgggaatc gaacccgcga catcagcttg
    11041 ggaagctggg attttaccac taaactacac ccgcgataca aaaacagtat acgcctcttt
    11101 cactccttcc tcaagttttt ttattcttta cgcttccgat atgttttgta gtaaaataaa
    11161 actaatcaat caattattgg agaagatgct atgacgggaa aagaattaga tctgttgctg
    11221 gacacttgtt tactcgctgg gaaaatcatg atggaaagca atgcggagat gtatcgggta
    11281 gaagatacga tgagtcgaat tgctttagct tctggaaatt tccgtttggt cagctatgtc
    11341 actcaaaccg gtctctttat tggtcttgat cgtacctcga ccatccgaat ggaacaaatt
    11401 accaaccgtt cgattaattt agaaaaagta gtaaaagtaa atgatctttc acgtaaatat
    11461 gttgcttcag agctaacatt agaagaactt tactgcgaac tgcaagcaat cgaccgagac
    11521 cgttctttct ttcctgtctg gttgcaaatc gttagcgcgg cagtgatcag tggaacaatt
    11581 atggtgttat ttggcggaaa gatgaccgat ttacctgtga ctttagtcat tggaggattg
    11641 ggatacgcag cttatctata tagtttgaaa ttttttagaa tcaaattttt atcggaattt
    11701 ttatcttctt tattgattgg catagccgct atctacagcg tacgttttgg cttaggaagc
    11761 aatcaggatc taatcattat cggatgtgtg atgcctttag ttcctggagt tcaaattacg
    11821 aacgctatcc gtgatttgct agctggacat tatgtctcag gagtttctcg cggaacagaa
    11881 gcgatgatga ctgctacgat gatcggtttt gcgattgctt ttattttcca gcttttttat
    11941 taggaaagga acacaagtat ggggacgata tttattcagt tttcttttag ttttttagcg
    12001 actgcggcat ttgccgttat tacaaatgta cctaggcgtt cattgatttg ttgtggtctt
    12061 tctggtgctt ttggctggat gatctactgg atctgtgttc aaataggcgg atctgctgct
    12121 tttggttcat tgcttggttc tttaggagta gcattcatca gcgatctttt ctctaaacgt
    12181 ttgaaaatgc ccgtaacgat tttcaatatt cccgggatgg ttcctctagt ccctggtggt
    12241 ttagcttatc aagcggttcg aaatctcgtt actgaatcct atcgagaagc ggctcattat
    12301 gcggtccaag caattatgat tgctggagca atcgctttag gtcttgtatt atcagaagtc
    12361 tttaaccata acatccgtaa tttcaaagta aagcgtgacg caatcatgat gaaacgaaaa
    12421 aaacggcttt ttaaataaac gaagtgtaac aaagaaaagg ttgtgaaaga gacgttcagc
    12481 cttgagcgat gacaaaatat ctcacaaaca ttgcgacaag taaccgcagg agcaataaga
    12541 agtaattatg agtattaaaa aaagttttgt aaaaatagct tctcacattt ttacataaaa
    12601 ttgacttaat actgagaaac tgacttttga acaccctcta tctgtaaaaa aggggctgcg
    12661 acatgatttt tgtcacggcc cctcttcttt attcaaattt tttccaaaac gttcgttgat
    12721 aataaacgat ccatagagcg gaaagtatta gaactaaacc gatcacagga atattcacta
    12781 accaaaatgg ataaaacaaa gccaacattc cgtataagac gataagaata atactgatga
    12841 tcaatgaacc catcatagtt gcgactaaac ccaaacttcc tgaacctctg ttaaataatt
    12901 ggttaatatt ggtccagttc agcagcagca accgataatc tctagcgaaa taacgtagtg
    12961 acaataagta gcagccgaat aaagaaccaa atagcaagct agggataaaa aacaaaggca
    13021 gctgaaaaga cagtccgctt aataatgcga tcccaccagt taaaaaactc tgcaatatcc
    13081 atccgaatct gaacttttct tttaaatatt ggttcataga gattggcaaa gaacggataa
    13141 acagaaaatt ttcttgatcc aaagaaataa gattgctgat aaaagaagtc tgattaactg
    13201 ttaagaaagc caatgcgatc cctaccagga aaacaacacc gattaactta ttatctaaat
    13261 cagttaattt tatttcgcct cctagggcaa aagcaagaat aaaaatgatt ggagttaaca
    13321 aggaagaaga aagaacttgc ataatcaaat taggttcttt tactaattga gcattgtaac
    13381 taaataaaag ctgatgcaca ttttggttct ttttatgggt tctttttatt ttgaactcac
    13441 tgtttgaatc agtcagttgc tctgtaagct ttggtactat cagctgtttt acagcaagga
    13501 aaaatcccag agccgtgata gctagtattc cccaacccaa taaaccttgt tgagaaagtg
    13561 gctgactggc agcatcatag aatggcaata atatcgaaat cggatgccga tctgttaact
    13621 cattttcaat agtccccgtt tgatgattca tccacatgat tccagcaaat gcgatcagca
    13681 tcgagctgcc aagcaagata ctagaaactg tttttctatg ttttttaaac actgctgttc
    13741 gagccaaacc aaaaacaatc aaactagcca gacaaaaaag aataatcaaa aatagagaaa
    13801 acaaaaggat tgagataatg atagtaagca aaatccctag atcagctcgc catccggtta
    13861 aaataaacat gactagaagc ggaaaaacaa aaggaatgat ggtcaaagca actaccaaaa
    13921 tctttgctga aaaaacctgt tcttgtccaa aaggcagagg caaaaatact tgcaggtcat
    13981 ttccttcaaa aaagatatta taaatgactg atatactttg agttaaacct aacataccaa
    14041 aaagtgccac gtaataagta aagaaacctg gcaatttaac aaagttcata gcaaacatag
    14101 caaatccgta aatcagtaaa aaaatcagcc ctgaaaaaag attttgagac aaaagataga
    14161 tagttaatcg ctttcccttt tttcctttct ctcttgcttt attcgtgagc tgtggattaa
    14221 catataaaag attaactcga attaattcta ataattgtcg cttatacata cggtccatct
    14281 cctgtcgctt gccttccagc cattttcaaa taaatctttt ctagcgtttc atcaggtgag
    14341 ccattcaata attcactaac tgccccctga taaatcaatt cacctttctt caaaatagcc
    14401 agtttatcgc ataactgttg tgcggtatcc aatacatgtg tagaaaaaat gactgttttt
    14461 ccttttgcgg catgagcctt catcatttct ttcaaatcaa atgctgcttg aggatcaagt
    14521 ccttgcaaag gttcatccaa tacccaaata tctggatctg gcagcaacgt gccgatcaaa
    14581 atcgtttttt gacgcattcc atgtgaaaaa cttgcgattg tttcattttg atgactatac
    14641 atatcaaaaa gcgctgtcaa ttctgctaaa cgcttttctt ttttttgtgt gtctaattca
    14701 taggcagctg aaatcaagtc ccaatattct ccagccgtca attgtaaaaa aatatctggg
    14761 gaatcaggca cataaccgat tttttgtttg atactcaatc gattttccgt caatttcatt
    14821 ccatctacta aaatcgttcc cgatgatggt tcaataatac taactaaact tttaatcgta
    14881 gttgattttc cggcaccatt atgtcctaaa aatccaaaaa tttccccttg tcttatcgag
    14941 agagacaagt cttttaatgc ttgttttttc ccgtaacttt tacttacatt gatgaattca
    15001 atcatttctg tactcctttt gtttgttatt actttttatt gtacccttcg ttattggtgg
    15061 agtaaatgtc aaaaagagtg cataacaaaa aaggatagaa acgactaggc tgctacttgg
    15121 gttgttctct tctacaggaa aacactcttc taacaggtaa gatatgagtc tttgttttct
    15181 ttaaaatgat tcattttcta tcttttcttg cataaaattc tttagtttat caatacttct
    15241 ctttcccatc tctagttgtt ctccatttgc aaatgttact atttcgttta ctctgctaat
    15301 agatgtaatg ttttcagtat taatgatata agcttttaaa tctttacata aatactcata
    15361 ttcgagtgat tttttatatt ttttaattgt gccgtttacg agaatctctt catctttcaa
    15421 tactaggcct attttatttt tataacctgg catgctcatt agataaagga tttcatcgta
    15481 atggatatag tgatcgctat taccataacg gacagttgtc cacctttttt tcgtagcatg
    15541 ttgaacagga tagttttctt tttctttcaa taagtaactt tggatgcttt ttttattttt
    15601 ttcataagtg aattctttta tcaaataacc actaggcgta atctttcgat taataacagt
    15661 tattgcttta ttcggatgag acgttagata aacaatttta cacttttcat tcttttctct
    15721 aagcatttcg cctagttcga taccgctata ataggcgttc aaatcgatgt ctaggaaaaa
    15781 aatatctgag gaatagattt cattattttt aatgaattca acaaattgta taacgttcaa
    15841 tccctgaacg atctcaaatt tccaaggact taataaaatt ctggattctt ccaaaatttc
    15901 tactagcatt ttttcaaaaa ccaaactatc atccaaaata aatatacgcg ttaccataaa
    15961 aagtacctcc actcgatatt ttactatcaa aatcatttca tacaactttt caacatacat
    16021 gttaggaata aattgtaatt ctcttcacaa tcttttccaa cacctttgaa accgatatca
    16081 aatactttca ggatgctgct tctaaaataa atatcaaaca aatgaataca tcatgcaaaa
    16141 aaagccagac aaccgacgtc cttgcgtgtc agctgtctga gctatgttta tttattttgt
    16201 tcttttaaaa agaacgatac acatactgat ttttcggagc agagactttc tcagcgtttg
    16261 taacaactac agatgggatt tcacgcttga atggttgata atagtctgat tggatggttc
    16321 cttctatttt ataccattca tcatttttaa ccgttactcc ttccggcata tgcgtcaaca
    16381 aaccaaagac tcctgaatct gccacacaat ggataatgcc gaatcggaac aagaagatat
    16441 ctgtattgct atcgttcggt gtttggtaaa caaatccttc atagctgatt tttttgccaa
    16501 tgaattcgct agggtaatta taaattagct ccataacttc taaatagttt tcatctgtga
    16561 tcttgatagt ttgcttatcc ccatactttt ctttcaactc attcatttgg tctaagtagt
    16621 ctgatttgtt gaaataaata ctggtatccg gctttaagta ttgtgtctgc atctccggat
    16681 cccctactga ttctttactt actgggaaat taaatccttt ggcttctacg atcgtagtgt
    16741 cgagactaac tgttggaaac aacgtcccca cgattactgg caaagctagc agtacataag
    16801 cgattccacg ttgataaggt tttgacaacc catggtcatg atcgtgctcg tgtgcctttt
    16861 cttctgcttt tccgtttttg acccacaaat acagctgaac taaagccaaa agagcagata
    16921 aaatcattga aagaatagct aagtagcgat aatggacatt gatatattga tcgagtttgc
    16981 cagaaacttg caagtacatc atcaattcga aatacccaga taaaatcaaa aaccgcagca
    17041 tattttccct cctaaataaa taatgtgaat ccaataacgc taagggcaat cagtccgatc
    17101 agcgataaaa taaagcgtcc tgtaaaatat cgtttcatca tcagtagatt tttgatatcg
    17161 accattgggc caaagaccaa aaaggcagct acaggtgctg tgccgaacag acttaacaaa
    17221 gaagatccta taaacgcatc tgcttctgag caaagagaca tcgtaaaggc caataacagc
    17281 atgatgataa tggctaaaat ctttgttgag ccgagcgtta gcataattct agttggtaaa
    17341 taagtctgca tcgcagctgc gattaatccg ccaatgatca aataacgacc tgtatcaaaa
    17401 aattcgtcga ttgaatgtgt caacacatgc ccagtttgat ggatcagctg attttttggt
    17461 tcattcttct cactttgttc ttcttcatgg acatgatgat ggtgattttc tgctacttta
    17521 gacgtgattt tttctttcaa tacagcgtct ttttgaaaat aggcaagcca gacaccaatc
    17581 acaagggcaa caaaaaagct gcctatcacc cgccagcttg ccatctgcca agaattgcca
    17641 aatgcgataa aagtggaaaa aatcacgatt ggattgatga tcggagcagt cagcataaaa
    17701 gcaaacgctg tgtgaactgg tacgcctttt ttaacaaatt gatgaacgat cggtacgatg
    17761 ccgcattcac atgaaggaaa gaaaaatcct aagatcgaac cagtaaaaat agagaagata
    17821 cgattttcag gaagccatct cttcacacgt tctggggtca aaaatacttg taaggcgcct
    17881 gagataagac agcctaataa tacgaaaggt aatgcttcaa taacgatcga taagaaaatc
    17941 gtactcatct gcaaaaccga atttggaata aaagaaaaca tgagtttcct cctttttatt
    18001 tctagttcat tcgctttgca aatatacgct tttattcaaa aaaaacaagt tgctctgtaa
    18061 atttttacac aactcttatt ttttaccaaa gcacttcaat tgactttttc tgttattccc
    18121 attaaattaa ggtctcatac atatcacttc tatcataaaa gggagaataa aaatgaaaca
    18181 aaccactaac ttgactgaag ttcaagacat actgcaacag tcatccgttg ccgtcattta
    18241 tctttcgatg cctaattgca gtgtttgtca cgctgttcgt ccacgactag aggaacttct
    18301 cacacattat gatattccgg cacttcattt ggatgcattt gaaacaccag aagtagctag
    18361 taaatttgaa gtgctgactg cgccagttgt cctgattttt catcaaggaa aagaagtctt
    18421 tcggcaagca cggttcatcg actttaaaaa aatccgttat ctactagatg aactgacagc
    18481 agaagatgat tccctttctt atgaagaaat cttccgaaca aaataatcgt tgtccaaaca
    18541 gaaaaaagcg attgaacaag tgaaagtttt gccttcattt gttcaatcgc tttttatttt
    18601 tattctgctg tattttcgga atgcgcattt gcgtcagaat gcaagaaata gatcaaggtt
    18661 tgcaattcat tcgtcaaatc aacattttgg atcaatacat ctgacggagc attcaatcga
    18721 gcagcggtaa agttcaagat tcctttgatt cctgcttccg ttaactgatt gactacttct
    18781 tgtgctcttt cagcgggtat cgttaaaatt gctacttcga tttgttggat cttgatttgt
    18841 tctgacatat cttccattgg ataaacgggg ataccgtcta cgatgcgccc aacgatttcc
    18901 tcattcacat caaaagcaca actgatacgt atgctattac tttgatggaa tttgtatttt
    18961 agtaaagcac ttcccaagtt ccctacaccg atcagcgcaa catttgtcaa ttgatcgtcg
    19021 tttaatgtct ttgcaaaaaa gtgcataaga tcttctacat cataaccata cccacgtttt
    19081 cctaattcgc caaaataaga aaaatctcga cggatcgttg cactatctac ttgaacggct
    19141 tcacttaatt cagttgaaga cacttttttc tttccagcat tatttaaaat ccttaaatag
    19201 cgataataca aaggcagtct tttagctgtc gcctttggaa taatatgatc tttcacgaaa
    19261 tgacctccac gtattgtcta attacatctt tgatttctcc atcatagcag tatttatagg
    19321 aaaaaatcaa ttccattgct cagatattgt gaaattttat tctttattca tttatttatc
    19381 atttctgcaa atctcgcagt ataatggaat ttatggtaga ctactaattg aaaaatagtt
    19441 ttttatttga ggagaattca caaagtagaa aagaggattc catgatatta ttacaagcca
    19501 atcagattgc tcgccatttt ggtgcagaag tcttatttga aaacatacat ttagaaatca
    19561 gtacaggcgc tcgtgtcgct ttagttggca gaaatggcgc tggaaaatcg actttattaa
    19621 agatcattgc tggaattgaa gcacctgatg aaggaaagat cgctaaaaat aaaacagcga
    19681 ctctcggata cctcgctcag gacacaggac ttgattccaa tgaaacagtt tggaacgaga
    19741 tgctgaaagc ttttgaacaa gttagacaaa tggaagagcg gatgcgcgag ctagagattt
    19801 tcattagcga aggtacgcca gacacacctg cttatagttc ttatttaaaa gaatacgacc
    19861 ggctgcaaca cgatttttca gatcgaaacg gctatggtta tgaaaatgaa attcgttccg
    19921 tattgcatgg gtttaaattc gattcttcat tttatgatca gaaaatcgat actttatcag
    19981 gcggacagcg cacacgttta gctttagctc gcatgctttt gcaacaccct gacattttga
    20041 ttctagacga accaacgaac catttagata tcgagacact ttcctggctt gagaattatc
    20101 tgcaaagcta tactggtgca ttattgattg tttcccatga ccgttatttt ttagataaag
    20161 tagtcaatga agtctatgaa ttaagcagaa gaaaaatgcg ccattacaaa ggtaactatt
    20221 cgaaatatct agatttgaaa gcagaacagt tagcaagtga atggaaggct tatgaaaagc
    20281 agcaaacaga aatccataaa ttagaagact tcgttgctcg gaaccttgtt cgcgcctcta
    20341 ccacaaaacg agcgcaaagc cgcagaaaga cattagaaaa aatggaccgg ctggatcgtc
    20401 ctcaagggga tgaaaaacaa gcaaactttc tattcagtat agaaaagcct tctggaaatg
    20461 tagtcttgca aatcgaagat gccgctatcg gatatgataa tgtcacctta tctgaaccaa
    20521 tcaatctaga tatccgtcgt caagaagcga ttgctctagt aggtccgaat ggtatcggga
    20581 aatcgacgtt gctgaaatca atcattcacc agatcccttt tatccgtgga aaagaaacgc
    20641 tagggacaaa tgtcaccatc ggctattacg atcaaggtca agctgatctg catacaaaca
    20701 agacgatcct agcagaattg tgggatgagc atcctaccac tccagaaaaa gagatccgaa
    20761 gtgctttagg tgctttctta ttttctggcg aagatgtaga aaaaccaatc cctctgctaa
    20821 gtggcggtga aaaagcacgg gttgctttag ccaagttagc gatgaacaaa gaaaattttt
    20881 tgattttgga tgaaccaaca aaccatttag atattgacaa caaagaagta ttagaaaatg
    20941 cattgatcga ttatgacggc acactgcttt ttgtttccca tgaccgatat ttcatcaatc
    21001 ggatcgcgac aaaagtcgtc gaactctctg aaaatggcag caaagtctat ctaggagact
    21061 atgattatta tttagagaaa aagcaggaag aagaagaaat cgccgaattg ttggcacaag
    21121 atgagccaga atctgctcct gctcccacga acaaatctga ttattaccaa agcaaagaac
    21181 agcaaaagct tatccgtagc cttcaacgaa aaattactca ggttgaagaa gaaatggcgc
    21241 ggatcgatga atggatcgat cagttggaac aagaaatggt cgcgccagaa aacctggaag
    21301 atcacgtaaa actcaatgag ctgaaccaag atttagaagc tgctagacaa gatcaagaaa
    21361 caaaattgac ggaatgggaa gaactaagct tggaattaga agaatatgaa aattaacgaa
    21421 aaaaccaaaa cagaaaccat tcatgctgtt ttggtttttc tttttttatt ttatcaaaca
    21481 aaaattccat atttaccttt ttcaccaata agaagaccaa ttactagtca ttctcactaa
    21541 agcttctaaa taatagtaat caccccaaat acaaggtgta tttaccccat tatttttggg
    21601 cttattataa acagactgtg ttaaaaagcc atcttcttct tccgttgtag catatctttc
    21661 tttcaattgt cgcataattt tccaaacagc agactggtat aagttctttt ctgttttgtc
    21721 taatagacct gattctatta attctaataa tccacaaacc atgatcacca tactagatgt
    21781 atctttttct tctctgctag aatcatcaaa gatcaaatcc caataacaaa tggtatcttc
    21841 tggcaaccga ttcataaaat aattggctaa tattttgctt aaatcaaaat atttttgttc
    21901 tttcaaataa cgataactta atgcaaaacc gtaaatcccc catgcttggc ctctagccca
    21961 acaggaatta tcactataac cttgatgcgt acttccatat cttggttttc catctttgac
    22021 atccatataa aatgtatgat aagttgaacc atcttctctt actaaataat ctgctgcatt
    22081 ttgaatatga gcctgagcag cttttttata tttttgattt ccagtttctt cactcgccca
    22141 atacaataat ggaagattca tgcaacaatc catgatcatt ctaccttgtt gtgaaggatc
    22201 actaggatct ccccaagctt gtataactcc tgccttctcc caaaaacgct gaagtaatgt
    22261 ttctgcagca tcaattgaag cttccttcat ttttcgattt cccgttattt tataatctgc
    22321 tacggttgat aaagaataca aaaaaccaag atcgtgatga ttagtgataa tttgacagtc
    22381 aatcctgtgg ataaaatcta tatctgcttt ttcagctgtt tgttgaaata aaggatcacc
    22441 cgtcttctca aataacaacc aattaattcc tgtccaaaat ccttctgtcc aaccaatatt
    22501 gtctcttaat ggataacgtc cttttatagg acactcgctt gggaattgat actgactgtt
    22561 actgatacgt ttgattaacc tctccgtgtg tctgcgacaa cgctcgatct cattattcca
    22621 ttctttttcc attaattctt tataacattc atttatccat ttttctggat gtattatctc
    22681 ttcaaacatc actttatcaa gcatttcccc accagccttt agcataattt tagtcttttt
    22741 ttattgtttt tattttggat agttagcccg gttgtcccat caaaatcaat tttgggacga
    22801 ttgttccata cttctaaact ataatcccga tcttgatgag caaccactcc tgttccgagc
    22861 caatgggttc cttttccaaa tgtaccctct aatccaggaa taaaagtgtt ttcccatgtc
    22921 atcaagtttg tattgggcaa acccataata gctgtggatt ttcgtttaat agtatcgtca
    22981 cttaaacaga taatacctga aaagccagct tcactcaccc tatagttttc cttgtcttct
    23041 tctatgatta ttccttcttt ctcaggagaa cattcaatag caaaccctgt ctcatataga
    23101 acatattctg tatctaattc tactttgtgt acgcgaatct gccagccttc aaaaggaata
    23161 agccaagttc tgatttttgc ctgtaaagta ggttcccatg tagaggcaag tacctctttc
    23221 ttacatacaa tgtctcgtac attatttcga acgatgaact gtccataggt tttgatgctc
    23281 tcattcttaa aactggtcgt gatatatgtg tccgctcgct gaatccctag cattgaatcc
    23341 attgccattt ctgctttcaa ttgattcgct cgcggtatcg aaaaaccaaa ttgactagaa
    23401 taagcaaatt ttaaatattt ttcattggtc aatgtatgga aatttggccc taattgtccc
    23461 gcattcaaaa aaaatgtatg tccattatca tgttgtatga gcaaattggc ttctgaaaga
    23521 agtttagttc cttcacgaat aggcataggc atttctttag ccgtccaata ctcatggtct
    23581 tcaggtagcg ccaacaataa aaaaatctta ttcagccata atggagataa cgtactatta
    23641 tagggttcag tcaatgtcaa ttgagggtag gtataaccaa tattcaggat acctttttca
    23701 tcaaatattt ctttttgcat ccaccatctt atattccgat tgactaaccc cttgatttca
    23761 cctaatttaa aaggcaaaag atcggcccac aacatagctg accaaaagct tgaaactgca
    23821 aaacgataaa tcatgcttcg accaaaaggc acatttgcac catcttccgc aaaaaaatga
    23881 atatagtctc tagaaaaatc aatagctcgg ttcttatata tctggctaat gggcttttct
    23941 ggttctagta cgctataaat caaaccataa taatgaaatg caaaaggatt ataataatct
    24001 tggcgacctc ttgaactgtc tcgataccag ccattttgaa gataacaatt ttctatatta
    24061 tcaaatgctt ctttcagtgc tgattcttta actggataac caaatttttg gataattgtt
    24121 ccgacaatta tcttaaaaaa ttgccaatta ccatctgcac attcatattc aaaaatttgc
    24181 gagaaccaat gaataatctg gcttttttct cctgtatcta attttttcca taataattgt
    24241 tcatgatgat ataacgctaa taacattgcg ggcatttcta ccatacgctg gtctctttca
    24301 tgtatttctc cccaataatc gggatgggaa ggatctgttc cagcttttat tcctgataga
    24361 attaatttca accatcgttc atctaattgg tcaattgcgg gccccgctcc ccataaaacc
    24421 cgagagaatc cttccattcc tgcaatttta tttccatatc ctaccccttg atgtatataa
    24481 tcaatttgtg cgccacttgc tcgataaaac ggctggagtg gttgatttat ctttttaaat
    24541 aagtcaaagt aatcctgtct ggtccttaat agtggtactg gatgtttcat tgtattttct
    24601 cctcttttta ctaccaaata gctaattccg actgttctaa tcgaagtaag ccttcaataa
    24661 aaaaataatc agaatagatc agtggcacat tataagtcag ttctctatgg tatgcttctg
    24721 ctccgcctcc aatgatccca tcttcatcca tattccaatt tgcatagtgc ttttctgtct
    24781 tttggagtat attgatagca gcttcatgat acatttttga tcgtacagag gaaacatatc
    24841 ctgctaattc cagaagaccg catgcagcgc atactccagc actggtatca atattcgaat
    24901 cttttacagc aaaatcaatg agaggaatat aaccagtttt ttcgattttc tgaataaaat
    24961 ttactgctat cttttctgct atagctagat agtacggatt ttttgtgtaa cgataactta
    25021 acgcgaatcc atataaagcc catgcatttc ctctgctcca acaagaattc tcattgtatc
    25081 cttgcccgcc aagtaaccga atatatttcc ctgattctgc atcaaattct gcgatatgcc
    25141 cggttgatcc atctttcctc actagatact tagctgttgt atctgcatgc tgccgagcaa
    25201 ttttagagaa cctcggatca ccagtttccc tcgaagccca atacagtaat ggtaaattca
    25261 tcatactatc aataatcatc caaccaggtt tatggtcatt ccatgctact aaatagttcc
    25321 ctgaaatatt atagcgtcca gcaagtaccg tagctgcatg taaccctagt tgtcgactat
    25381 gtttgttttg agactgttga taatgtgcaa tagccgatgg taagaataaa aaacctacat
    25441 catgatgaac gtctgaaaaa tggtacaggg cagattctaa taattgttct tgttgtattg
    25501 ctgcctcttt gaacttttct cgttttgtct tgtgaaagag ctgccataaa ataccactcc
    25561 aaaaaccatt ggtccaccag tcgattcctc tgtcctttat tacgtctgta tattttccgt
    25621 tgtaagaaat atatggaatt ttattcccca ttctgtctaa ttccgcatct atcttttcag
    25681 aagctacatt caaaattttt cttgaccatt ccttcgtctg ttcattcatg gatatcccgc
    25741 cattctttta atttttatga atgtggagtt gctcctagaa cgaactagat ggttaacatt
    25801 cgttattttt tttacttatt tgcagctcca atgtcattct ccttaaattt agactgcgcc
    25861 cacacataaa tcaagaccat tgggatcact gaagttgcta aaattagcat aattgcgcca
    25921 taattaattg gctcacctgt actagaaacc gtcatatttt tgataattaa gggaaccgta
    25981 tatttatctt tatctgaaag catgactaat ggaaatagat attgattcca acttcccata
    26041 aagataagta aaccactagt aataatcgta ggtgataaaa tcggtacagc gattttcgta
    26101 aaaatcaccc actcattggc accatcgatt ctggcagcct ccatcagtgc tgtaggaaat
    26161 tgactgctat attgtcgcat cataaacact gaagttgtac tggcaatcga agggatgatc
    26221 acacctgcat aagtattcga taatcctaaa cgactcataa tgtaaaataa aggaatcaat
    26281 gtggtaaaaa aaggcaccat cctagatagc ataactgtat tgaacaacag tttattcccc
    26341 ataaaacgat actttgctaa tgcataaccc gccattgtag aactggctgt agctgaaact
    26401 gtactgatta cagcaataac aatcgaattc caaataatca agggataatt atatctcgcc
    26461 atgatggctt gccagttttt taatagcata tccccaaact tgaaattgat tccgccactt
    26521 aaaatttctt gattactttg cgttgaagct acaatcatat ataaatatgg catcaaaaat
    26581 attaaggcac caaacacaat aatgacgtac gtaaaaattc tgctttgtat cttttgttta
    26641 gtcattttta tcacctccga atttaaattg aatagccgat aatataacag atacaaacac
    26701 catcgtccag gcaatagcag aggcttttcc aaaatcaacc atttcaaaac ttgttttata
    26761 taaattgact cctacgacca aagctgaatt ttctggtcca ttggaagtcc caaagaatat
    26821 atttgggata ttgaaattac ccaagccatt gatagtggct aaaactgtgg ccattaaaat
    26881 gattggcttt agcatgggga tcgttaataa aaagaattgc cgaaatttcg atgctccatc
    26941 tatttcagca ctttcgtata tctctttaga aatcccttga agaccagcta aaaataaaat
    27001 agtgttatat cctacactaa gccaaatcat cgtgatgatc attgatattc gtatccaaaa
    27061 aggatttgtt aaccactgta caccgttaat tcctagcgca ttcaaaaatc cattgaataa
    27121 cccagtcgga ttgaaaaaag tcatgaatac ggaagctaca gccaccgttg atgtaatggt
    27181 tggaatataa tagacagttc taaaaaatcc ttttcctttt aactgtgctg aattcaataa
    27241 aacagcaaag taaatagcta atagcatcgt tattggaatt gatcctgcca tgataatcaa
    27301 aacattcgtg taagatttaa taaacaatgg atctcggaag atagctagat aattgtcaaa
    27361 tccaacaaat tcaaatgagt agccaatttt cataaaacta aaagcaaacg agataatgat
    27421 gggaatcaaa atcgtcacaa taaagaaaat aacaaaaggt gtgaccaatc cataagcact
    27481 ttttttatga gacgtatctg ttgctttttt cttgctgttc tttattgtct tgcttggtaa
    27541 cgaagattgc atcatcgtta agtcctccta atatttttta atcaccagtt aattttacgc
    27601 cgtacttatg agcaaaattt tctgcttctt ttagatatga attttcaaaa tcacctgttt
    27661 gccaatagtt atatgcagcg gtagtcaaat aagacgtagc atctgaataa gtggctggta
    27721 aaacagtatt tgatgtattt tcattgattt tattcaatag ttcatagtat ttttgtcctc
    27781 cttagtagtc aaactttttc tcagctgctt ctgtttgata ggccaatgag ttagatgtag
    27841 ccacgcccag ctccagtgcg ttggctaagc attcttcatc tgtcagcata aatgtaagaa
    27901 attgttgtgc cacttgtgga tttttggcat ctttagggac ataaaaactt gatcctcctg
    27961 atactgcacc ttttcctgga ttttcttttg aaaaaggaat cagtggagcc atgcgccatt
    28021 tgtcagatgc atcaggaaaa ttcaaagaca tattcgtagc ataccagccg ccagcaacaa
    28081 acattgcaga ttcttgaaat gctttctcag catcttgtgc accgtagaaa tgtacaatat
    28141 ctgagtcgat catttctttg attaactttg cagcatgttt cgcttcttta gtattcagac
    28201 ggatatttcc ttcttcatca agcaaagatt gattctgctg ggctagcatg ttgataaaca
    28261 attcttggtc cccagattct ggcaaggcaa ttccaaaact accagttttt tcttttaatg
    28321 cttttgccac ctggatatat tcttcccaag aactgatttc ttcaaaatct acacctattt
    28381 cagcaaattt ttttggttga taataacaaa gtgctggggt aaaatcacta gcccaaggaa
    28441 taatcgtttc attactcgtt tgttgacgca aaatattcaa tttttgatca taaaactgat
    28501 cgccatattt gtcataaaat ccatattcat cagcactata aaaagcatct tgaaattttt
    28561 ccagcacacc tgctgctgaa gtgtctgcca tggagataat atccggcata tcttcgtgtg
    28621 ttaccaattt tggggtgatc atttgtactg ttgctgttcc cgaagctaca ttcacaattt
    28681 ttaagtcaat atttgctcca gttttgcggt tatagatttt tgcagcattt tcaacatagt
    28741 ttgtcagttt gccgtttgcg acatatactt ctaatgtagt ggcttttttt atcattggat
    28801 ctgcgatgtt tgctgttact tcttcgttag tttttccaca tgcacttaag ctgaataata
    28861 gggtaatgtt tagcaaagct atcaccaatt tgtatctttt tttcatgtct atcccttctt
    28921 tcttttcaag ttcttatata aaacgctttc acttatgtat attaacggaa ttagtaacac
    28981 aaatatttat ataaaaaaat attttacttg tcgttttggc ttttcatttt tgttataata
    29041 gtcattaatt ataaatagaa agctttttat ataaaaagag aaaggaaagt ggttcttttg
    29101 ttaacaaaca accaatcctc caatcttgtc aaaaaaacac taacctattc catagatacc
    29161 catcttcatt tatctgctgc tccctatttt cgactactaa taaatgaaag cgctaattta
    29221 tatgctgaat ttgcacataa atctatagaa ctagataatc cttccctttt attcattgat
    29281 aaacagcaag aagtccaaat cttttctact caaaaggaaa cacaaacttt tatcattatc
    29341 cagttttatt ttgatgagca attattagca catattacgg gacaatcttt ttctatagat
    29401 caagaaataa catctatcat tacttttctg aaaaatgaac agttcaaaat tgattatcta
    29461 aaacatagta agccagctat ttcctatgat caggaaatca attctttttt catactatgc
    29521 caacagatga gcattcattt gctttcctta ttagttactt attgtctgca aaaaattcaa
    29581 ttgtcttcct taccaaggca ttatcaacag gaacttgctt tattgacaat accttcaaat
    29641 gagaaagtca ttcctaaaaa aaagcatatt ctttattcag atgaattagt tgatccaatc
    29701 atacgatatt tagaagaaca tctttcagaa aattttttgc ttgaacaatt agcccaaatt
    29761 ttttttatca gtccagccag cttaaaaaaa cattttagaa aagtgaatgg aaaaagtgtt
    29821 attagctatt ttaaagaact aaaaatggaa aaagcaaaac gtctcgtgct agaaaatgaa
    29881 ttaacctata cagaaattgc agatatatta ggatttcatt cgatccatca tttttcttca
    29941 gcttttaaaa aatatacagg gttatcccct tcaaagtatt atctatcctt aaaatagaaa
    30001 aaaattttta ggttttatcc acaaattatt tctctatatt ttctgtctat tcaaaataaa
    30061 caataatttt ccggcacaat tatttgctgt tttttaccat aacatagtac gatcaacgta
    30121 gaaaaggaga tgtttttatg aaagttgttg tcattggcgg tgtagctggc ggtccttcat
    30181 ttgccactcg tttccgtcga ttgaatgaag cgcacgaaat cattatctat gaacgcggag
    30241 aaaatatttc ttatgcaagt tgtgctttgc cttattattt aggaggtgtg atcactgacc
    30301 gtgactcgct gatcgaacgt acaccagaaa tattgaaaac aaaaaacaac atcgatgtct
    30361 ttactaaaca cgaagtaaca gcaatcgatc cttctactaa gcgattaaca gttaaagacc
    30421 tatccacaaa tgaagaaata aaaacagatt acgataagtt gatcatctct tctggtgcta
    30481 gaccagatta tccggatatt cccggagttt ttgaagcaga aaacggcttt gtcctccgta
    30541 gtgtgacgga tgcggatcga atcaaatcgt tccttgaaga aaaaaatcca caacatgtcg
    30601 tcattcttgg tgcaggtgtt atgggtctgg aattagctga gaatttcaag catcgcggct
    30661 tagacgtgac tttaatcgat caattgccac aagtcgcttt cccttatgat ccagaaattg
    30721 ctaatttagt ttatgacaaa ttgctgaaag aaggattagc cgttcattta gaaacaagag
    30781 ttactgagat ccgtgataaa ggtcgagaaa tagtattatc agatggctcc gtcctttctg
    30841 ctgatatgct aatttttgct gttggtgttt ctccgaagaa tgaagtggtg aaagcaaccg
    30901 gcatacaatt atcagataca ggtcagatca ttgttgatga ccagttacaa accaatctgc
    30961 cggacatcta tgcgattggc gatattatcg aaacgactag tgtagtgact ggtcagccga
    31021 tccaaagtat gctttccagt gcggccaatc gtcaaggaca tatgctggca gatattttaa
    31081 atggtacgcc tatgcgctat cgcggatata ttggtgcagg tgtcgcaaaa atctttgatc
    31141 atacagcaag ttatgcggga atgacagaac atgaattaaa agcatcaggc ataacaaatt
    31201 ataaaactgt ttttatcact ccctttgacc atgcctattt ctatccagaa gctacaagat
    31261 taaatctaaa gctgattttt gatgcagata gcggtcgtat tttaggtgga caagcatttg
    31321 gagaaaaagg tgtcgataaa cggatgggag aactttctgt agcaatcacc ggaaacttga
    31381 cagtctttga tttgcctgat ttggagttgc cttactctcc accgtattct actacccgtg
    31441 acccgttgaa tatagctggt tatgtcgcaa tcaatcaaat gacgaatatc gtagaaacga
    31501 tcaaagcaag tgatataccc gaaaacgatt tgaaagaagc gttcttttta gatatacgtg
    31561 aacctaataa agcaccttct ggcagtatct cggcaacaaa aaatattcca atgaatgagt
    31621 tacgagatcg aatcaatgaa atcccaaaag ataaaaaagt ttacattact ttcagaagag
    31681 gattgaatac ttatacttct gcccgaatct tggcaggttt gggtatcaaa gcgattttga
    31741 ttgaagaata aaaaaacgac cgcggtgggt agccgcggtc taggagttat ttttacttga
    31801 ggagtaaaaa tgaaaaagta tatagggttg ttggttggta tgtatataga atagaagata
    31861 aatgtgaaga aattgtgcat tatttcttca catttattag gttatagttt aagaaagttt
    31921 aaacattgcg caatttaatt attttagctg tttcttttca taaaaaaaca tgttgtgact
    31981 ctgagacaaa tcatagtcca tagtgatgtc tctagagtaa ctacgcctaa tattacgagg
    32041 catcatatta atctatcagc actagtacct aaactagcat ccctttcgaa tattttttct
    32101 tatataataa agtttgcttt cactcctcta atctcaccaa atcgactggc ttgcgttgtg
    32161 tgatactagg aactgattgg tttagaacga cttttctatt gtaatcatat ttttcgccat
    32221 cctcgttgtc ttctaatcct tcaatgaatg atccctaatg tgtgtattaa ataatttaat
    32281 ttttttgttc ctatttattt
//
LOCUS       DAFEEZ010000029        31650 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000029
VERSION     DAFEEZ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.029"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            214..1500
                     /gene="efmA"
                     /locus_tag="LP245_001418"
     CDS             214..1500
                     /gene="efmA"
                     /locus_tag="LP245_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBL1519343.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(1638..2237)
                     /locus_tag="LP245_001419"
     CDS             complement(1638..2237)
                     /locus_tag="LP245_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HBL1519344.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            2641..3762
                     /gene="mnmA"
                     /locus_tag="LP245_001420"
     CDS             2641..3762
                     /gene="mnmA"
                     /locus_tag="LP245_001420"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBL1519345.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            4008..5429
                     /gene="arcD"
                     /locus_tag="LP245_001421"
     CDS             4008..5429
                     /gene="arcD"
                     /locus_tag="LP245_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBL1519346.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            5443..6561
                     /locus_tag="LP245_001422"
     CDS             5443..6561
                     /locus_tag="LP245_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBL1519347.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(6621..7913)
                     /locus_tag="LP245_001423"
     CDS             complement(6621..7913)
                     /locus_tag="LP245_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL1519348.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            8045..8623
                     /locus_tag="LP245_001424"
     CDS             8045..8623
                     /locus_tag="LP245_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1519349.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            8752..9129
                     /locus_tag="LP245_001425"
     CDS             8752..9129
                     /locus_tag="LP245_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBL1519350.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            9062..11134
                     /locus_tag="LP245_001426"
     CDS             9062..11134
                     /locus_tag="LP245_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL1519351.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEGKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(11345..12292)
                     /locus_tag="LP245_001427"
     CDS             complement(11345..12292)
                     /locus_tag="LP245_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1519352.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            12538..13002
                     /locus_tag="LP245_001428"
     CDS             12538..13002
                     /locus_tag="LP245_001428"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBL1519353.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(13064..14107)
                     /locus_tag="LP245_001429"
     CDS             complement(13064..14107)
                     /locus_tag="LP245_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBL1519354.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(14484..15449)
                     /locus_tag="LP245_001430"
     CDS             complement(14484..15449)
                     /locus_tag="LP245_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBL1519355.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            15683..16528
                     /locus_tag="LP245_001431"
     CDS             15683..16528
                     /locus_tag="LP245_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1519356.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            16719..17906
                     /locus_tag="LP245_001432"
     CDS             16719..17906
                     /locus_tag="LP245_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL1519357.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            17912..18268
                     /locus_tag="LP245_001433"
     CDS             17912..18268
                     /locus_tag="LP245_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBL1519358.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            18270..18608
                     /locus_tag="LP245_001434"
     CDS             18270..18608
                     /locus_tag="LP245_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBL1519359.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    18684..18940
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            19003..20037
                     /locus_tag="LP245_001435"
     CDS             19003..20037
                     /locus_tag="LP245_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1519360.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            20030..20716
                     /locus_tag="LP245_001436"
     CDS             20030..20716
                     /locus_tag="LP245_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1519361.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            20740..21588
                     /locus_tag="LP245_001437"
     CDS             20740..21588
                     /locus_tag="LP245_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL1519362.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            21785..22558
                     /gene="sufC"
                     /locus_tag="LP245_001438"
     CDS             21785..22558
                     /gene="sufC"
                     /locus_tag="LP245_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBL1519363.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            22571..23857
                     /gene="sufD"
                     /locus_tag="LP245_001439"
     CDS             22571..23857
                     /gene="sufD"
                     /locus_tag="LP245_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBL1519364.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            23854..25089
                     /locus_tag="LP245_001440"
     CDS             23854..25089
                     /locus_tag="LP245_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL1519365.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            25076..25546
                     /locus_tag="LP245_001441"
     CDS             25076..25546
                     /locus_tag="LP245_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBL1519366.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            25551..26942
                     /gene="sufB"
                     /locus_tag="LP245_001442"
     CDS             25551..26942
                     /gene="sufB"
                     /locus_tag="LP245_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBL1519367.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(27040..28182)
                     /locus_tag="LP245_001443"
     CDS             complement(27040..28182)
                     /locus_tag="LP245_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1519368.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(28233..29030)
                     /locus_tag="LP245_001444"
     CDS             complement(28233..29030)
                     /locus_tag="LP245_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1519369.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNSIIAKFLTDNHDKFKNN"
     gene            29232..29531
                     /locus_tag="LP245_001445"
     CDS             29232..29531
                     /locus_tag="LP245_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1519370.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            29796..30671
                     /locus_tag="LP245_001446"
     CDS             29796..30671
                     /locus_tag="LP245_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519371.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            30668..30886
                     /locus_tag="LP245_001447"
     CDS             30668..30886
                     /locus_tag="LP245_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519372.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            30873..>31650
                     /locus_tag="LP245_001448"
     CDS             30873..>31650
                     /locus_tag="LP245_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HBL1519373.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYE"
BASE COUNT        10421 a         5606 c         6630 g         8993 t
ORIGIN      
        1 ttgtaaggac gacgcaaatt agttgtcttt tttattttta aatttaacac atgttgttat
       61 ttttaatatt ttgctgattt attgtttcta agtaaagaaa tttaaattga aacgattgtt
      121 atttagggaa aaaggtattt tttgaaaaaa gaatcccgta taatgattgt tgtgcaaacg
      181 ctatacaaaa tgaaaaagaa aagagggatg tttatggaaa atgaacagtc ggtcgtttta
      241 acgaattgga agagaaatta tttgttcttt ttatcgggac agtttttgtc aggaatcact
      301 agtatggtcg tccaatatgc gatcatctgg tatttgacaa gagaaaccgg ttcggcgaca
      361 attttgagtt ttgctacttt actaggaatg attcccatgg ttttactaag cccatttgta
      421 ggaccgctag tggatcgctg ggataaaaaa gctcttttga ttgtcacgga tattattgta
      481 gcgattttcg cgcttatttt agcagtagtc ggaacgattt cagaatcctt cccgatttgg
      541 ctagtttttg tgtctttgtt tatgcgttcg gtcgcacaaa cattccaaat gccaacgatc
      601 cagtcgatta tgccgacaat cgttccatct tctcacataa caaggacgaa tggacagtta
      661 ggaatggtcc aatcagcgaa tttcatcatt gcgccagctc taggtgcggc tttgttttca
      721 gtcgttcctg tcaattacct tattttatta gatgtattgg gggcagtttt tggtgtcggc
      781 ttattgattt ttgtgaagat cccaaaagtt tctcctgaaa tattggaagt tccgcttact
      841 atttttaaag atgcaaaatt tgggctgcag caattgatgg ataataaagg gttatggtac
      901 ataacgatca atggtgcatt tgtgatgctg ttgttcatgc cagcaatcag tctgtatcca
      961 ttgatgacgc tagattactt tggtggttcc gttggacagg cgggagcagt ggaagtagtc
     1021 tacgcagtcg gaatgctctt aggcggtgca ctgatcagtt ttataggaac atggaaagac
     1081 cgaatgaaac ctattattat agcctacatc attatgggcc tgacgatcgg tgcaagcgga
     1141 ttggttccaa acgatagtca agggttcttg tactttctta tcttgaatgc aggagcaggt
     1201 tgtgcaacgc catatttcaa tacactgctg atggcaatga tccagcagag ttatgaatcg
     1261 aatgttttag gtcgtgtctt agggaacttc aactctttga tgaacctggc aggtccaatt
     1321 ggattattat ttgcaggacc attagctgat cgtttagggg tagaaaaaat gttcttgttt
     1381 tccggaatcg ggattttatt atgcggaatc gttttatttt taacgtcagc tgcccgaaat
     1441 tatgataaag aattacagaa aaaactggta aaagaacacc atgagcaaaa agacgaatag
     1501 tatggaatgg agttgtgaca gaagtcttgt tacaactcca tttctgatcc taatgttcct
     1561 gtggcaataa gcctactcaa atgaaaaata tgagtaatta tctttatttg tttaatactt
     1621 gatatagggc agttttttca cgacctatcg tacttcctct ttgcttcata gatttctttg
     1681 atttgttgct cagataacgg agtgccaaat ggtagttttt cctttaagag ttctctttcc
     1741 ggtgcgtcta cgcctacatt gacatcgttc tcgataggta cgctgtaatg atggatatgt
     1801 ccatgaagat tgcggatagt gtcgttaggc ccgagcaaca tcggataatg agtcaagtaa
     1861 tattgttgat ggtcgaattt aacgatggca cctacatcat aaaaataaaa tttgggactt
     1921 ccgtcagtaa gcctaggatc atttttttct aaataacgga aaaaagcgcg actgtcatgg
     1981 ttccctttga tcaagtggat tgttccttgc agttgagtga ccagttccaa aatttctgca
     2041 tttgcttttt catattgcgg atgcatagca aggtcgccta gatgataaac atggtcggtt
     2101 tcttttatta ctgcattcca gctagtgatc aactgttggt tcatttcatc cacatttgca
     2161 aagagccgcg gagcaaagtc gttttttcct aataagcgtt catggaaaaa gtgcatatca
     2221 ctgataaagt aattcatgta tcttttgcct cccttttttc ttagagtaaa caaaatcact
     2281 tatctgagca actcataaca tctaaaaaga aaaggttgta aatgagacgt gcagctttaa
     2341 gcgataagaa gcaattttga aaaatagttt ttcacaattt ataaaattat tccttattgc
     2401 cgaaaggctg gcccttttta tgagtatgcc aattttttat atcgaatgct caaaagatga
     2461 gtgatttttt ggttgactat catgtttgtg tactgaatag gtccagtaga acagtatttt
     2521 tacgacttga taattaaggg atgaaatttt cagaaatatg acgtataatg taaaatactg
     2581 aaaagttgcg accttcaact cgtagatgtt tcagaatcta attgaaatga tggtgatatc
     2641 atgacagaca acagcaaaac acgcgttgtc gtagggatga gcggcggtgt cgactcatct
     2701 gtaacagcac ttttgttaaa ggaacaagga tacgacgtga tcggaatatt catgaaaaat
     2761 tgggatgaca cggacgaaaa cggtgtatgc acggccacgg aagattataa ggatgtagcg
     2821 aaagtagctg ctcaaatcgg gattccttat tactctgtga attttgaaaa agaatattgg
     2881 gatcgtgtat ttgaatattt cctagccgaa taccgcgcag gacgtacacc taacccagac
     2941 gtgatgtgca acaaagaaat caaattcaaa gcattcttgg attatgcaat ggatcttggc
     3001 gccgattatg tagctactgg acattatgcg caagtcactc gcgatgaaaa cggcgtggtc
     3061 cacatgcttc gtggagtaga caataataaa gatcaaactt acttccttag ccaattatca
     3121 caagaacagc tttcaaaaac gatgttccct ctaggcggca tggaaaaatc agaagtacgg
     3181 gcaattgctg aacgcgcagg ccttgcgact gctaagaaaa aagattcaac gggaatctgc
     3241 tttattggtg aaaagaactt caaacaattt ttgagcaact atctgccagc aaaaaaagga
     3301 aatatggtca ctcttgatgg tgaagtcaaa ggacaacatg ctggcttgat gtattatacg
     3361 attggtcaac gtcaaggact agggatcggt ggcggaggag attcgcaaga accctggttt
     3421 gttgtaggaa aagatctagc gacaaacaca ttatatgtgg ggcaagggtt ccatcatcct
     3481 gcattgtatg ccacaagctt ggatgcaagt gaaatccact ttacgacgaa tgaaccaatg
     3541 ccaaaagaat tcaagtgtac agcgaaattc cgttatcgtc agcaagacgt tcctgtgaca
     3601 gttcgcttat tggatgataa tcgtgcagaa gtcgtattcg acgaacctgt acgtgcaatc
     3661 actcctggac aagcagttgt attttatgat ggaatggaat gtctgggtgg tggtttgatc
     3721 gaccacgcat atcaagaaac aaaagtttta caatacgttt aagcgatatt aaatgaatca
     3781 aaacagctat ggctaacaaa agaaacacct tttcttttgg atagcatagc tgtttttttg
     3841 caataaaatt aatttttatt cattttatac ttgaaatact tgtgtaaaaa gttcataata
     3901 tccaataata tgaataaagt tgctttttgt taagcaagag cagttgcaaa atagaaggga
     3961 atcttttgca agtgatttgt tcaattttat aagtgagggt gatggaaatg gaaaagaaat
     4021 cgacgggtat tagcaaatgg ggactggttg ctctggttgt cagttcgtca atcggaagcg
     4081 gtgtgtttgg gatcacaagt gatctggcta gttctgcagc tccagggcca gcgatccttt
     4141 catggataat cgttgggatt ggtattttag ctttggtatt atcgctgaat catttaggag
     4201 aaaagcgtcc agatctagat ggtggtattt tcggttacgc ggaagcttca tttggtaaat
     4261 taggtggctt catcagtggt tggggttact ggttgtctgc gtggctggga aatgttgctt
     4321 ttgcaacgat gctgatgagc gccatgggag aatttttccc gatattcaaa ggtggacaaa
     4381 atgttccttc tattttattt gcaagtattt ttatttgggg tctgacttta ttagtaaaca
     4441 atggagttga aggagcgagc gtcatcaata caatcgtgac gatctgtaaa ttagtgccat
     4501 tattcctatt tttaatattt gtatttatcg catttaaagt gaatatattc actgctgatt
     4561 tttggggtaa cgtatctgat aatctagtga atggaacagg gcagcaagga acgatctggt
     4621 tgcagattaa aggttgtttg atggttatga tgtgggtctt tgtagggatc gaaggcgcaa
     4681 gtgttttagc caaccgcgcg aagaaacgtt cagaagccca gcaagcatcg atcattggtc
     4741 tgctttgttt attgtttatc tatatccttg cttcgatctt gccatacggc gtcttatctc
     4801 aagaagagtt agcaactatt tcacaacctg ctatggcaaa tattttaaaa ggaatcgtgg
     4861 gaaattgggg agcagcgctg atcaatatcg gcttgattat ttcgatcatt ggttcttggt
     4921 tgtcttggac gatgctccca gcagaaacaa cgatgttgat ggctcgagac ggtctgttgc
     4981 cgaaaggttg gggaaaaacg aataaaaaaa atgccccaac ttattcgtta gttgttactg
     5041 caatcttgac taatctattc ttattgactt tcttagttac tgattatgcc tatcaatttg
     5101 cctattcttt atgtacagcg gcaattttga tttgttatct acttgtcggg atctatcaag
     5161 tccagttttc tttaaaagaa ggaatcaaaa aacaagtagt gatcggtggg attgctgtag
     5221 tttttgaatt gatgggcatc attttagcag gattttctta tgtcctttta tgtagtattg
     5281 cctatcttcc tggtttttgc ttctactgga tcgcttgtcg tgaaaccaaa catcaaatta
     5341 cgggaaaaga aaaagtaatg attgggctga tttgtgtggc cgcactgctt tcaatcgggt
     5401 tgcttgctgt aggctggatc aagatataag ggggaaagaa acatgaaaat cgcaaatttc
     5461 ggtgtagaag aatggctaaa taaatgggaa aagaaagcgg tatatgatat tgcacaaagc
     5521 tcgatcgaag cattgacatt agacgaactc gttggcttag atgggactag cgtaagtaaa
     5581 tttttcgaaa aacgcaaaaa cgaaccattg gactatggct ggatcgaagg atcagatgtt
     5641 ttcaaacaag aagtcgcttc tctttatcaa accgtcgatc cggaaaacat cttacaaacg
     5701 aatggagcga ctggtgctaa tcttttagct ctatacgcgt tagtggaagc aggagaccat
     5761 gttgtttcga tgcttcctac ttatcagcaa ttatatgaca tccccaaatc tttaggtgcc
     5821 gctgttgact ttgttcattt gaaggaagaa gaagattggc agtttgattt agaacagcta
     5881 gaagccttag tcaaacctga aacaaaaatc atctgtttga atagtgcaaa caatcctaca
     5941 ggcacattgc tagatcggaa aactttagaa aaaatcgcag aaattgctcg tacagtagat
     6001 gcatatgtat tgatagatga agtatatgcg cctttaacgg ataaaggtga attcttgtcg
     6061 atcgtagatg tctatgaaaa aggtatagca accaattccc tatccaaaac ctactccatt
     6121 ccaggtattc gtattggctg gacagctact ggacctgagt tggcagaagt ttttcgaaag
     6181 tatcgagact acacgatgat ttgcggcgga gtcctgtcag atgatcttgc tgtacatgca
     6241 ttgaagaata aagaaaaaat attggcgcga aacaaaaaga tcattacaga gaaccttgtg
     6301 attttaaaac aatgggtagc caatgaaccg aaagttgaac ttgtcgctcc caattacgtc
     6361 tctacttctt tcattaaatt agccatcgaa gaagatgacc agacattttg tatcaattta
     6421 ttagaagaaa caggagtact attagtacca ggaagtgcct ttgatttacc gaagcatgcc
     6481 cgactaggtt actgttgtaa aaaagaaacc ttggaaaagg gattattcct cttatctgag
     6541 ttcttgaaaa aacaggccta aacaaaaaca ctgcaaggac agtctgtgac aactgttcaa
     6601 gcagtgtttt tcatttacgc ttattgtcta tgagaaggag agtgccctga agctatggag
     6661 actcctgaag ctttttcttc tgcagtttct tgctgatgga tctcttgtgt attgtgtcgt
     6721 acaagcaaga agttgaccaa aacaagaaga gaagtcgaaa gaaagacgcc gcgataacca
     6781 aatgcactgg aaacactgga gccgatcata ggccctacta cgttaccagt tgcttggaaa
     6841 gattggttat aactgaagat ccgtccagca gcttgatgag gcgaatattt tgtgatcaat
     6901 gcttggacag cagggagcag acaagcatca gagataccaa tcaaaaaacg taaggcagct
     6961 aattgccaaa cattcgtgac gaatgccatt gggatataaa ccagaatcgc aaaacccaaa
     7021 ccaatcgcaa gtattctttc actcccaatc ttgtcaccta agcgaccaaa tcttggagcg
     7081 gctatcaaag tggcaatccc aggtatcgaa gcaatgattc cgctgatcaa cgtaacattc
     7141 ccatgtccat gcagcaattg gcgaatgtac agactgatga ttggactaat ggaattgttg
     7201 gatgcttgga tgatcatcgt tgtgacgaac ataccgatga cgacgtgtgg atatttcaag
     7261 tctttgaaaa tctgtttggc agaaaccatg ttttcttttt tcactgggac aaatttttca
     7321 tggacgaaaa acagactcaa caagaagacg aaaaataaga tgatccctgt aatgaaaaag
     7381 gtagggcgat agccaaacgc tgaagcagag atcccgccaa gaagcggtcc aagtaatgtt
     7441 cctgtaacag aaccagttgc taaggttcca agaacttgac cacttttttc ttttggcgtc
     7501 ccagttgcga caagggcagt ggcattactg atataaccag aaaaaatccc ttgaagcaga
     7561 cgcaatgcga ctaattgata cacactagtc acgcaaccca tcaaagaaat gacgattgcc
     7621 attcctaatg aagcacgcaa cagcatcaat tttcttcctt tttggtcggc taattttccc
     7681 caccaaggag agataagcgt agtcaccaag aaagtagatg aaaaagtcaa tccgctccaa
     7741 aagttcaatt gtgacgtact ataattacct aacgtatcta tgtaaagtga cataaaaggc
     7801 atgactaaac taaatccgat accagccata aatgttccaa accataagac aaacaagttt
     7861 tgttcccaag tttctctttt cctaaataat ttttccttta ttcttgcagc caattagact
     7921 ccttctttct gaaaattttc atctacagct ctttattata aactacaata tgtagtttat
     7981 caatgaaagt ctcttttttc tctttctttt tcgtggtaaa ctgaaagagt gaaggattta
     8041 ttttatgaga ggaaacatgg aaatgaaaaa aagaaatctg tctcaagaga aaatcatcga
     8101 ctgctttcga gaactagcag aagagatgga tgttcagcaa ataacctttc agcatttagc
     8161 caaacgcttg gatatcaagg ctccctcgct gtataaccat ttcaaaaata ttcgtgatgt
     8221 caaaacagcg ctaacagcga aacttctgca ggaacttaat gaccagctgc gacgggctct
     8281 tgtgggaaaa agtggtcagg aagcactgca gatctatgca gaaacttatc gatcctttgc
     8341 tttttcaaat caagcagtgt atgagttact gatcagtgta ccgcatacca atgaagctgt
     8401 tttattagat ggaatccatg aaacgaatca gatcattttg cagatatttg aggcttttca
     8461 attaacgaaa gaagaaaaag ttcatcgaag cagggaactt cgtagtatga tccacggtta
     8521 tctttcctta cgttttttag gatactttac aaaagaacca acaatcgatc cagaagacag
     8581 ctatttttgg atgatcaata actttatcgc tactttgcct taaacaatca gattcatttg
     8641 taacaatttt aagatgttca ttaaatgacc cttttataag agaaaattct tgcaactttc
     8701 ttgaaaagtg actaagatga gtctagaaaa gctgaaagaa ggagcacgag tatgtatcaa
     8761 gtaattacca tgttcgggga caatgagcct tggtggtttt ttgaagactg ggaagaagat
     8821 attgaagaag aagaaacatt cgagtctttc gaagaagcac gacaagcgta cgaaaaacaa
     8881 tggaacgaaa tccatcaaaa ttatgaatat atcaatgcaa aaagtaactt tctcagcgcc
     8941 ttttggaatg acggagatga gcgctggtgt gaagagtgtg acgatgattt acagcaatac
     9001 aagggacttg cgttgttgaa aaatcatcag cccatcacag tagaaagcag aaaggaattt
     9061 tatgaaacaa ctaattctag cggaaaaacc aagcgttgcg aaagacctaa gcaaggtgct
     9121 tggtgctaat caaaagcaca aaaattatta tgaaggaccc aaggtgatcg ttacttgggc
     9181 ccttggtcat ttattaggat tgaaaatgcc ggaagatctg aataaggaat ggcagagctg
     9241 gcaaatggac acgttgccaa tgatccctaa aaaactagga atcaaaccac ttcctaaaac
     9301 aggacatcaa ttaaaagcaa tcaagcagct ggctcagcga aaagatgtct cagaagcagt
     9361 cattgcgaca gatgccggaa gagaagggga acttgttgct cgctggatct tagagtatgt
     9421 gcatttcaat aaaccagtga agcggttatg gatctcttct caaacagata aagcaatcaa
     9481 aactggattc aagcaactaa gacctgcgaa agaatatgat gcattgtatg aatctgctct
     9541 tgcccgggca aaagcggact ggctggtagg attgaatgtg accagagcct taactgtgaa
     9601 gtacgcggat aatttatcag caggccgtgt gcagacaccg acactagcat tagtgagaga
     9661 ccaagaaaag aaaatcgagc agttccgtcc acaaacgtat ttcacgatca cgttgcaagc
     9721 tggaaaagaa caagccaaaa tgcttcaaaa aaatcaattt gctttaaaaa cacaagaaga
     9781 agcacaaaaa cttgttcaat tgatcagtac aagcaaagga actgtcacag aagtccaaga
     9841 aaaattaaaa acggaatctg cgccattgcc ttatgattta acagagatcc aaagagaagc
     9901 caatcaacgc tatggctatt ctgcaaagaa aacattaagt cttgtacaaa gtttgtatga
     9961 gacccataag atcgttactt atccgcgtac agacagcaaa tatctgacaa atgacatgaa
    10021 aagtacgatg aaagaacgat tgcaagcagt cagcgacttt gctcctgagg gcaagcagta
    10081 tttgaaaaac ggagccatcg tccaacagac aaaagtattc caagacagta aagtgaccga
    10141 tcaccatgca cttttgccaa ctgaaaacag agcacgttat gaaaaattaa gtaatgaaga
    10201 gcgaaaaatc tatcaaatga ttgtctctcg ttttttagga ctgtttgctc aaccccataa
    10261 agtcagccaa acaaaagtta cggttgaatt tggtaaagaa cgattcattt ttcggcaaaa
    10321 tcgtgtcgtc caagcaggat ggaaaggcga aactgaaact gagacggaaa cagtcaaatg
    10381 ggaaaaagga atgagaatca atcccgattt cgccatcaaa aaagaactat ctgcaccgcc
    10441 taaaccattg tcagaagcaa gcttgcttgg tcaaatggaa aaatacagtc tgggaacccc
    10501 agctacgcgt gcagagatta tcgagaaact aatcaaatct gaactgatgg aacgtacccc
    10561 tcaaggactg caagtatctc ctaaaggtaa gcaattatta gtattggtaa atccctcttt
    10621 agtaacacca gatttgacag aaagctggga aaaagacctt gaagctattg ctgcaggaaa
    10681 gaaacaagca ggaaccttct tgaatggaat cgaaaaagaa acaaaacgct tggtgaatga
    10741 gatcaaatca agcaaacaag aatatcaaga tttctcgatt acccaaaaga aatgcccaga
    10801 atgtggggcc aatctgcgcg agaaaaacac acgtgacggc aaaatctatg tctgcaccaa
    10861 ttcagattgc aactaccgca gaagaaaaga tccaaaagtc tctaatcatc gatgcccgca
    10921 atgtcaccgg aaaatggaaa tcatcgaagg taaaaacggt gcttatttcc gttgtaaata
    10981 cgatggaacg acagaaaaat tgcttgataa aaaagagcag aagaagaaaa tgaccaaaca
    11041 tgaagaacga cgcttgctga aaaaatatgc acaagcagaa gaaccagaag aaagcccatt
    11101 agcagcagca ctaaaagcag caatgaagaa gtaataagat atgaaagagg ttgtgataga
    11161 agtggtcagc ttcaagaaat aagaaggaat ttacgaaaat tgcttctcaa atttttgtga
    11221 aatttcggct tatttccgaa gaagctactt ctggaacacc atttattcgg aaaaaaggac
    11281 tgtgacaaga cttttgtcac agtccttttt catttaaaaa aatgtttact tcatttgacg
    11341 tatattattg gtgaggcttc aattcatttg gcttcacttt ttctgtttct cttatgatat
    11401 aaacaggacg ctgtttcgtt tctaagaaga ttttcccaat atatttcccg atgattccaa
    11461 gacataacaa ttggattcca ccaatgaaca ggaagatcga gaccatggaa ggccatcctg
    11521 atgtaggatc accaaacaac aatgcccgca aaataatgaa caaaattgca ataccagaac
    11581 cgacacaaga caaagcgccg ataaatgaag caatcgttaa cggtgcatcc gagaagttca
    11641 cgataccatc aatcgagtag ttgaataatt tccagaagga ccaagatgtt tcgccagcca
    11701 cacgttcgcg gttttcataa gaaatatatt ctgttttaaa tccgacccag ctaaataatc
    11761 cttttgaaaa tcggttgtat tctgttaatt ctaggacggc atccaccatt tgacgagtca
    11821 tcaagcggaa atcacgagcg ccatcgacca tttctgtatc gctgatttta ttgatcaact
    11881 ggtagaattt tttcgcaaag aaactgcgta tcgcaggctc gccttcacga gtcgaacgcc
    11941 gggtgccgac acaatcgata tcagaagtag tgatccggtt gatcatctca ggaagcagtt
    12001 cgggcggatc ttgcagatca acatccatca cggtcactaa atctcctgta gaagcttgca
    12061 atccagcgta cagagccgct tctttcccaa aatttctgga aaatgagaca aagcggacat
    12121 aaggataagc tgaggctagc ttcttgattg ctgctaacgt accgtctttt gatccgtcgt
    12181 caataaacaa atattcgaac tcatgggcac ctttgaattt ttcaacctca tcaaaaaaaa
    12241 gaggaacagt tttttcttca ttaaaacatg ggacaacaat tgatactttc atcgtttcta
    12301 tcctttcaat cgtatgttta tatatggttt acattcaaaa tttaataaac cttaaataac
    12361 acctttaaaa tttgatttta cgtaaaagaa caggtattct ttttgtaaac taacgtattt
    12421 agtttaccat gtttcctcgg tttatcaaac ttttaagaac aatttttatt agttggcaag
    12481 tagttttgga tagagaaaaa ggaggaagtt ccagtctatt gactaggagc aaacaaaatg
    12541 aaaatacaca cacctatcgg ctttttatgg ttagatgcag atgaatccgg attgactgct
    12601 gtatcttttc agccaatttc agaaagcgaa tcagcgaatc agcgaatttt aacgcgcaca
    12661 caagaacagt ttgaagaata ttttgcggga aaaagaaaag aatttgatgt tcctttatct
    12721 ataaagagag gtacgccttt tcagcaaaat gtctggaaag ctttgtcgac cattccttat
    12781 ggagaaatcc gaacgtataa agaagtagcc gttgctgttg atagtccgaa agctgtgcga
    12841 gcgattgggc aggcaaatcg aaccaatcca ttgccaatcg ttattccttg tcatcgagtg
    12901 atcgggcaaa atggaaaact gacaggatat atgggaaacg caatagatgg ggttgaaatc
    12961 aaacgccaat tgttgttgtt agaaggatat ctgcaaaatt aaaaacagtt gtgattcgga
    13021 cattgttcca tgcgagaatc acaactgttt tttcatgttc attctaaact ttgatcagcc
    13081 aaataaatag taaagccatc actgtttgga gaagcccgac agctaatcca taagataaga
    13141 agcgtgtacc ttctttcatg aattttgcaa agtctaaacg cagaccaatt gccgctaaag
    13201 cagtgatctc aaaccagctg ctgataaaat gtgccgattg gtcaataact acaggtaaag
    13261 aaaacaagct gttgaccaaa caaaagatca caaaccctaa tacataccaa ggaagcggta
    13321 attttcgttt tttctgcgta tcagttggcg tttcaaacag agctggttgt ttcttgtgca
    13381 tgaatttttc aaacagatag acaacaacaa cgagcatcat aatacgtaga atcttaaata
    13441 gcatggcgaa ttcgacaaca gaattgtcaa gtaagcttgc cccagcgact acttgaccaa
    13501 cagattggag tgtaccaccc aaaagtgcac ttttttcaat gagatttcca ccaaacaact
    13561 gtaatccaag aaaagggaga gtcaacatca tcacagtacc cagtagattg actagtgtga
    13621 tgatctgtcc tttttcttcc tctttcgcat ggatggaagg ggcgattgaa gcaatagcag
    13681 aagaaccaca aacagcgttt cctccagcca tcatcaaaga agaagtatcg ctgaattgca
    13741 gttttttacc aatcaagtaa gcaccgatga tagtgactga catttgcagt aacacaaaaa
    13801 caattccttt tacaccaatt tgagcaatcg tttgagctgt gacagttgca cctagtaaaa
    13861 aaacagagaa ttctaatagt ttgctttcag caaattttgt gccgattgct agaacaggct
    13921 gtttaaaaaa agtatttcct aataaaatac ccaataaaat agcaatagtc gctccaccta
    13981 actgtggcag ataaatagca agaagcctgc tgaaggcagc gatggcaaaa gaaagcagta
    14041 aaccgggtaa gatttcgcgg accgctgaat cctttacaga ttttattgga tgtgacaatg
    14101 atttcatttg atcggttcct ttcgtcaata aatactaaaa gcatactcga acatagtagc
    14161 actaaaccag tattttgaca aaagaacaag aggtcgtgac aaaagtcttg tacgacctct
    14221 tgtttcgaat aaacggtgtt ccagaagtag cttctacgga aataagccga aatttcacaa
    14281 aaatttgaga agcaattttc gtaaattcct tcttatttct tgaagctgac cacttctttt
    14341 acgacctctt ggtaaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaaccagta
    14401 caaaaacatg aacagctgtt tttgtttggc cgttcttatt acttgatgca gaacagcttt
    14461 ttcacaacct attgaatcga ttattaagcg atttttttag aaacaaattt tccatgtttg
    14521 ctatgttctt taattaagaa acgtacgtaa tgagcaagaa cgtagaagac aactacactt
    14581 gcaaacagac attccgcaac ttttaagaaa tccaatacgc tactatagat acctaaactg
    14641 ttgaagtaat gaacagtagt aaatatagct gttgcagaga taacaagcgg gaatgtaaag
    14701 gctgcatagc ttggataaaa acgaagcttg aacaaacgtg gaagcataga cagcacaacg
    14761 aaatacaata cttgagataa agcgaacaat gctacgacaa gataaaaatt aggttcagca
    14821 aagtttttaa gataacctgt taggcaaaga gaaccaggtg ctgcaacgat cgtaatcagc
    14881 ggacgtgtcg gatgagccat atttcttacg aaaaagacac gtttgatgat gatcggcaat
    14941 aagaacgcat agcagatcaa tgaaatccaa aagaaaattt ttccaataag tgggaagaag
    15001 ttcccggcag ttacagtgat gaccccaaat ccaacgtaaa tgataaacca gcttggataa
    15061 attgcttcaa ttgaaagatc agctttgata acatggtgat aattgaaata aaagacaagg
    15121 atcacttgga agataacagc gcacagccaa atgaatttga caattggtgc aatactttca
    15181 tatgaaacaa aataagtaca aataaccatg agtgacatcg taaaagttgg tgaaacggag
    15241 gcgatgattg gatcatgcaa cgtttgtttc gtgtgttcga ataagataaa caatttaaca
    15301 aaaatgaata tcataagaat catagagata ccgccagtta gattgcctaa agcaacatgg
    15361 tgatagtctt taaacagatt tccaagggaa gctaacccaa ggatcaaccc gcagatcggg
    15421 atcggaataa ttttcaaaaa gttcttcata tataatattc tcctttttat ttaatagatt
    15481 ttagtaccaa gatgaacgaa tacattgtaa aatgaatagg aatgtatgat tacgagcaag
    15541 cagacagctg attgtcttca tctaagttac tagttggatc agcaactgtt ttgttgtaca
    15601 tttctattat agatggtttt ttgtatattt aaatcaaata gtttttatag taattatcat
    15661 aaaaagttat ggaagtggtg ccatgtttaa gttattaacg acttttcgag cagtatatga
    15721 aacaagaaat ttttccagag cagcagaagt actgttttta tctcaaccag cagtctcgaa
    15781 tcaaatcaaa cagttggagc gggaattgaa tatcgatctt tttcaacgta acggaagaaa
    15841 agagatgctt ccaactaagc aagccgactt attatatgaa cggacactgg ttttgttaga
    15901 agaatgggaa gaaactcagc aaaaattgct caatgaacaa aatgaagaag aagtatgtcg
    15961 gatcgttgct tcccacacct ttgctgtcta tcttttgcct cagttgatga aacatctgat
    16021 caaaaggttt cctaaagtgc attttgagat cgaaatcacg aattctcatg aatcattaga
    16081 acaagtagcg aaacatgaat ccgattttgg ttttatcgaa aagccattag agacttccgg
    16141 cgtacaaaga tactctttga tggaagacca gctagtcatc gctggggacc caaaaagcaa
    16201 attgtggctt gtaagagaag caaactctgg tgtttttcat tacacgcagc gttattttga
    16261 agagatgaat atccaagata agaagatgat cgtgaaaagt aacgatgtaa ttgttgcgtt
    16321 gctgaaggaa ggaatcggtc gctcgatttt gtctaagcgc tctgttccag aaaatgtgcc
    16381 aatgactccg ttgaatttcc atcgatattt ttatttcatc caacgaacca atctggtttc
    16441 tgatcagctg ctagagattg ccgaagagat ccttcgatac aatgaaagca cagaaacttc
    16501 tcacagcgag gagaatctca gctggtagat aattgcatgt atcaaaaaaa gttctatgat
    16561 acactaaaga taagcagtag gcttttgtac tgcatttgct caagcaactg cacaaacgga
    16621 aagttaattt ttcccaaatg tctatggaaa gactttccat tatctaactg gaccgctata
    16681 ataatcagca gtatggtttt taagaaaagg gatgaaacat ggaaaaaaaa ttaaaagctt
    16741 cgaacgataa tcgtattgat tatggcgtga ttttaccagt ctttctgtta tgtttgattg
    16801 gtctgctctc attatatgta gcacttagcc atgatccgaa caatccagca gtcttgaaag
    16861 gcgtagggat gcaagttgtc tggtatttag ttggagcggc agcaatcgtt gtcatcatgc
    16921 atttgaattc caaatggatc tggaaactga ctccttacct ttatggtttg gggttagtgg
    16981 taatgggact cttgctcaaa ttctatgatc agaatttagc tgcttcaaca gggtctaaaa
    17041 actggtttcg attcggtgcg tttactttcc agccagcaga gttgatgaag attgcgtaca
    17101 tcttgatgat ggcactgatc gtaactaaac ataatacgca agtaaaagaa cggacgatga
    17161 aatcggactt ttggctgatt gggaagctct tgatcgtgac aataccggtt ttagcattga
    17221 tcatggccca agatgacttt ggaacgatgc ttgtctttct tgcgatcttt ggcgggattt
    17281 tcctgatgtc tggaatctct tggcgcatca tcgcacctgt agtaatcttg gcagtagtcg
    17341 ttggagcagg aacgatcttc ttggttacga ctgaaggcgg aagagacttg ctttataaag
    17401 ttggattcaa atcttatcag tttgcacgta ttgattcatg gctggaccct ttccatgata
    17461 cgtcaggaat gagttatcag ccggcccaag gacttttggc aattggtacc ggtggcttgt
    17521 ttggtaaagg attcaacgta agcaatatct atgtgcctgt tcgtgagtcc gatatgattt
    17581 ttaccgttat cggtgaaaac ttcggcttta tcggtggtgc attcgtcatt ttcttgtatt
    17641 ttattttaat ctatcgtatg attcgggtgt gtttcgatac gaataatgaa ttttacgcct
    17701 atatcgcaag cggtttgatc atgatgctgc tgttccatgt ctttgagaat attggagcaa
    17761 atatcggatt acttccttta acagggatcc cattgccttt cattagtcag ggaggatcct
    17821 cgattttagg gaacatgatc ggtatcgggt tgatattatc gatgagatac caaaatgaag
    17881 cacctgcaag atcttcaagg aggtaagaaa attgtacacc ttttactggt acccgaaatg
    17941 ttcaacatgc aaaaaagcca aagcgtggtt agaccagcat ggcgttagtt atcaaaccgt
    18001 tgatatgatc aaagaagtac cgaaggcctc aacgattgag acttggctag aaacgagtca
    18061 agtaccaatc cgtcgcctgt tcaacacaag cgggatgaaa tatcgggaac ttggactgaa
    18121 agatcaagta ggcgagttta cggcttcaaa agcgagccaa gtcttatcga cagatggtat
    18181 gctgatcaag cgaccactga tcttacgaga ggaccagctt gttgcaattg gattcaatga
    18241 aaaaatttat gaaggagaac tgatataaaa tggcaggcaa gcatttgaag aaaaaggaca
    18301 acctttggat cttatttaat ggaaaagaat actgtgttgg tttgacaaat gaagcgcaag
    18361 aagaacttgg agacatcacg tttgccaatc tgccaaaagc aggacaatcg ctaaaaaaag
    18421 atgaacctct gatcgaagtt gaagcggaaa aagcggtcaa tgaatttgcc agcccgctaa
    18481 cgggtacagt ttcttctgtt aatgataaaa tcggtgaaga tatcaatatc ttgaatgatt
    18541 cagatgaaat gaatgcgtgg atcttaagtt tcaaagatgt tgatccaaaa gaatttgacg
    18601 aattataaaa tcagaaaatc acttgaaaaa agttgacact gattcttcca gttgctataa
    18661 tcataagcaa tcctatatga aacgagaaag ctttgaaaag aagagtacat gtcacggacg
    18721 tttgaagaga gccctgtttg ctgaaaatgg gtaacgaaaa tgagatggaa gatggtctta
    18781 gagcagagta agcgagcgta agcaaactta ctacgggagt gcccgttaca gcgcgacagt
    18841 atacggaaag aagctaagtc caagtactgg aagaggctgt tattgcgaag taacggtaaa
    18901 tcaaggtggt aacacggaag ttcaagcttt cgtccttttg cttaaggcaa gagggcgaag
    18961 gcttttttgt ttgaaaaatt ataagagaaa gatgtgaatg gcatgtcatt aatccaacta
    19021 acgaatgtca aaaagacatt caatgggaaa aacggaaaca tccaagccgt caatgacgtt
    19081 tcactaaacg ttgaaaaagg ggatatttat ggaatcgtcg gctattctgg cgcaggaaaa
    19141 agtacattag tccgtctcct gaatggactt gagcttccca cgagcggcga agtgatcgta
    19201 aacgatcaag atattacaaa attaaaaaac aaagaattac gtacattccg aaagaaaatc
    19261 ggtatgatct tccagcattt caacctgtta tggtcaagaa ctgtacttga aaatatccag
    19321 ctgccgctgg aattagctgg cgtaccaaag agcaaacgta aagaacgggc agaagaactg
    19381 ttgcgtttag tcgggttaga aggacgcgga caagcatatc cttcacaact ttccggcgga
    19441 cagaaacaac gcgtcggtat cgcacgagca ttggcaaatg atcctgagat cctgctttgt
    19501 gatgaggcta ctagcgcatt ggacccgcaa acaacagaag aagtattaga cttattgtta
    19561 gcgatcaata agaaattgaa tttgaccatc gtcttgatca cacatgaaat gaatgtgatc
    19621 cgcaaaatct gcaacaaagt cgctgtgatg gagttgggga aagtcgtaga agaaggagac
    19681 gtattgactg tcttcagaca accgaaaaaa gaagtaacca aacgctttgt acaacaagac
    19741 atcgaaccag aagctgattc gacagaacta ttagctgaac tcatcaaaga aaatccaagc
    19801 ggccgtttgg caactttgac ctttagcgaa agaaatgcca acgagccagt catttcccaa
    19861 gcgattcgac gctataacat cgatgtcaac gttgtgtatg gaaagatcaa acaagtgaaa
    19921 gaaggttcct ttggttcatt gactgtcttg atgactggtg aaaccaaaga attagatcaa
    19981 gcagaagtgt tcatcaaaga acaaggagta ggaattgagg tgatccatcg tggataaaag
    20041 cttttcagaa acatatctag attttaaaca aatcaacccg gaaacgatga atcaggctat
    20101 ccttgataca ctatatatga cattaatctc aatggtctta gtgacgatca tcggattagt
    20161 tttgggattg atcctttact ctattggacg caaaaacaaa ccgtatgctc gaatcattta
    20221 tggaatcgta tcgatcatca gtaatatttt ccggtcaacg ccatttatga tcctgatggt
    20281 tttgatcatt ccatttacta aagcaatcgt aggcactatg ctaggtgcgc aagcagccat
    20341 tccagctctt gttttatccg cagcaccatt ttatgcccgt ctagtagaga ttgcttttcg
    20401 tgaagtcagc cctggtgtac tggaagcagc agatgcaatg ggagcaagtt actgggaaat
    20461 catctggaag gtcttgatac ctgaaagtat tcccgcattg atttctggat taacagttac
    20521 aacgatctcg atgatcggat ttactgcgat ggccggcgcg atcggcgcag gtggacttgg
    20581 aggtcttgct tggcaggaag gctaccagcg tggtaatcta acagtgacat tcgttgcgac
    20641 tttaattatt ttactaatcg tatttatcgt tcaaggaatc ggtgatttct taactaagaa
    20701 aacagacaaa agataatagg atataggggg atgtaggata tgaaaaagaa aatttttgga
    20761 tttgcagcag cgcttttgct gactgtagga ttagcagcat gcggtaacaa cagcgacagc
    20821 aaagattcag caaataaagc agacgacacg acattgaaag tcggcgcttc accgacaccg
    20881 cacgcagaga ttttggaaca tgtgaaacca ttattgaaag atgaaggaat cgatcttgaa
    20941 atcgtcaaat tcgatgacta tgtattaccg aaccaatctt tggaagaagg cgacattgat
    21001 gccaattact tccagcatat tccttatttg aacaaagaaa tcaaagaaaa aggatatgac
    21061 tttgtcaatg ccggtgctgt ccacatcgaa ccaatgggct tgtactctaa aaaagtcaaa
    21121 gatgtttccg aattaaaaga tggtgcaaca atcattactt caaattctga atcagactgg
    21181 ggacgcatca tcacaattct acaagatgct ggcttagtca aagtcaaaga tggagtagat
    21241 ctggaaacag caacattcga tgatattgaa gaaaacccta agaacttgaa gttcaaccat
    21301 acgatcgacc catcactttt agcttctacg taccaaaatg atgaaggtga cctagttgca
    21361 atcaacgcaa acttcgctta cggcgcaggg ttgaatccat tagaagatgc cgtattgctt
    21421 gaaaaggaca actctcctta cgtgaatatt attgcgactc gtaaaggtga tgaagacagt
    21481 gacaaaatca aaaaactgat tgaagtgctt caccgcaaag aagtccaaga atggatcaca
    21541 gacaaatggg gcggctctgt taaaccagta aaggctgatg caaaataagg tatggaacaa
    21601 aaaagatgag aaataagtct gtaatggctt atttctcatc ttttttatac ctattctaat
    21661 ttagaaatca aaattgttta ataataaata aaagatattt gattttagta aggaaggtca
    21721 ttgcgcttca ttctcaatta gtctaaaatg agtgagaacg aaagagaatt tgggggtata
    21781 atgcatgtct gtcttagaaa taaaaaatct acatgtgtcg atcgaggaaa aagaaatcct
    21841 taaaggcgta aacctaacaa tgaaaaccgg agaaatccat gccatcatgg gacctaacgg
    21901 cacaggaaaa tctaccttat ctgccgctat catgggcaat ccaaactatg aagtaacaga
    21961 aggcgaaatt ttgtttgacg ggaaaaatgt tttagacttg gaagtagatg aacgtgcgcg
    22021 acttggctta tttttagcta tgcaatatcc aagtgagata ccaggtatca cgaatgcgga
    22081 attcatgcgt gcagcgatca atgcgaaacg tgatgaaaac gacaaaattt ctgttatggc
    22141 atttttgaaa aagttagatg aaaaaatggc tttactaaat atgccagaag aaatggctga
    22201 acgttatctg aacgaaggtt tttctggcgg agaaaagaaa cggaatgaga tcctgcaatt
    22261 gttgatgtta gaacctacat ttgcaatttt agacgaaatc gattcaggtc tggatatcga
    22321 tgctttgaaa gtcgttgcta aaggagtaaa tgaaatgcgc ggagacaatt tcggtgcatt
    22381 gatcatcacc cactatcaac gattattgaa ctatatcaca cctgatgtcg ttcacatcat
    22441 gatggaaggc cgagtagtca tgacagggaa tgctgaccta gctaaacgtc tggaagcaga
    22501 aggctacgct ggtatcagta aagaattagg aatcgactat aaagaagaag aagcgtaagg
    22561 gggagcaaga atgaaagaaa aaaactggct cgattatctt gacgcggtaa atgatttttc
    22621 tttaagtaaa ggcgaacctg attggatgag aaccttccgt caagacgcac tagcgaaagc
    22681 agatgaactg ccattgccgc atatcgatcg ggtgaaattc catcgctggt cgttatttga
    22741 tgtgaaagaa acacaaacca tcagtgaaac aggcacgatt ccggcatttg atgcaatgaa
    22801 agacaatcct gtgcttgtcc aacaaggttc atggacgatt tttgaacaac tgcctgtgga
    22861 attagcagaa aaaggagtca tttttaccga cttgttcact gcaatgatcg aatatccaga
    22921 actagtccaa gaatattata tgaaaaaagc agtaaacatg aacgaagacc aattgactgc
    22981 actccatgta gcttttatga acagcggtat tttcctgtat gtgcctaaaa atgtcgtgat
    23041 cgatgaacca ctcgagtcct tattcattca agatggcgca tccgatgagc acttcttcaa
    23101 gcatgtgttg atcgtggcag atgaacatag tgaattttct tatctggaac gtttccagac
    23161 aaccaaagaa caagtagcaa aatcatcagg taatatcatc gtggaagtca tcgctaaagc
    23221 tggttcaaaa atcaaatatt cagccgtaga tcaattagga gaaaatatta cttcttatat
    23281 gaatcgccgt gggcacattt tacgagatgc ttctgtcgac tgggcaattg gtgtcatgaa
    23341 tgacggtcat gtgatcgctg actttgactc agatttagca ggagaaggtg cacacgcaga
    23401 agtcaaaatc gtggcaatca gctcgggcag acaaatccaa ggaatcgata cacgagtaac
    23461 caataaagcc cctcatacga tcgggcatat tttgcaacac ggagtgatcc gagaaaaagg
    23521 aacattgacc tttaatggta tcggccacat cttgaaaggg gcaaaaggtg cagatgccca
    23581 acaagaaagt cgtgtcttga tgctttctga taaagcacgt ggtgatgcga atcctattct
    23641 tttgatcgat gaaaacgaag taactgctgg acatgctgcc agtgtaggac gagttgatcc
    23701 agaagaaatg tactatctga tgagtagagg attgcataaa gaagaagcag agcgcttagt
    23761 gattcgagga ttcctcggtt ctgtcttaac agcaatccct gtagaacaag ttcggaaaga
    23821 attagtcgaa gtaatcgaag ggaagttgaa tggatgatcg atgctaaaaa gctacgcaat
    23881 gattttccta tcttatttca agacgtcaat gatgaacctt tagtttatct ggataatgca
    23941 gcgacgaccc aaaagccaaa acaagtactc caggcattag cgtactatta cgaacacgat
    24001 aacgccaatg ttcatcgcgg tgtccatacg ttagcagaac gcgcgaccca tgattatgaa
    24061 caagcaagag aaaaagtacg ggcgttcatc catgcaaaag aaacagcaga agtgctgttt
    24121 actcgtggta cgacgacaag cttgaattgg gtagccagaa ccttcggcga ccgctatatc
    24181 aaagcaggag acgagatagt gctctcttac atggaacatc attctaatgt tatcccgtgg
    24241 cagcagttgg caaaacgaac aggtgctgtc ttgaaatata tcgaactaac agaagaaggc
    24301 ttcctggata tggaggatgc agcgaaaaag attacggaca aaaccaaaat cgtctccatt
    24361 gctcatgtat ccaatgtctt aggtgtcttc aatcctgttc aagaattagc tgaacttgtc
    24421 catgaaaacg gcggggtcat cgtagtagat ggtgctcaat ctgccccgca catggccatt
    24481 gatgtccaag cactagactg tgatttcttt gctttcagcg gacacaaaat gtgcggacca
    24541 acaggtattg gtgttttata tggtaaacga aaatggttag aagaaatgga acctgttgaa
    24601 tttggtggcg aaatgatcga ttttgtcgaa ttatacgaca gtacatggaa agaactacct
    24661 tggaaattcg aagcagggac accaaatatc gccggcgcta tcgcattagg ccatgcaatc
    24721 gattatttgc aaaaactcgg tatggacaat atccatcgat atgaagaaga actagccgct
    24781 tatgtgttgc caaaattaca agcaattgat ggattgactg tttatggtcc acaagacccg
    24841 aattttcgga caggagtcgt tgcattcaat ttggatgggt tacatcccca tgatgtcgcg
    24901 acagctttag acatggaagg ggtagccgtc agagcaggtc atcattgtgc gcaaccgcta
    24961 ttgaagtacc ttgaagtatc agcgactgct cgcgcgagct tttatttcta caacacaacg
    25021 caagacgccg accgtttagt tgaagcaatc atggcaacaa aggagttttt ccaacatggg
    25081 actatctaaa ttagacaatt tataccgtca agtgatcttg gatcattctt cccatccgca
    25141 tcatcgtgga agcttgactg actcgacaag caagatcgaa ttgaacaacc ccacatgtgg
    25201 agatgtgatc gaattgcaag tcgatgtaaa agacggaatc atcaaaaata tcgcctttga
    25261 cggcagtggc tgctccatca gtacggcaag tgcctcgatg atgacagacg ccgtcatcgg
    25321 aaaatcaata gaagaagcag aacatttaac tgtagacttt ctacagcttg tccaaggaaa
    25381 agaagtcaaa gatcccgacc aattaggcga tgctgctatg cttggtggtg tagctaaatt
    25441 tcccgctcgg atcaaatgtg cgacacttgc ctggaaagca ctaggaaaag caatggaaaa
    25501 cgatggtacc gcagctttcc atcattacca caaggaagag gagtgagaac atgggcgtac
    25561 cagaattaga agaatataaa ttcgggtttc acgatgatgt cgaaccggtt ttcagtacag
    25621 gagaaggctt gacagaagaa gtgatccgtg agatgtcaag aatcaaaggc gaaccagaat
    25681 ggatgcttga attccgtctg aaatctctag aaacatttaa caaaatgcca atgcaaacat
    25741 ggggccccga cctttcagac atcgatttcg atgccatcaa atattaccaa aaaccaagtg
    25801 acaaacccgc tcgtgactgg gaagacgtac cagaaaaaat caaagataca tttgaaaaga
    25861 ttggtatacc agaagctgaa cgagcttatc tagccggtgc ttccgcacaa tatgaatcag
    25921 aagtcgtgta ccataatatg aaagatgaat tcgaaaagtt aggaatcgtc tttactgaca
    25981 ctgactctgc tttgaaagaa taccctgaat tattcaaaga gtacttttca aaacttgtac
    26041 cgccaaccga caacaaatta gcagcgctga attcagccgt atggtcaggt gggaccttta
    26101 tttacgtgcc aaaaggcgtc aaagtcgatg ttccattaca aacgtacttc cggatcaatg
    26161 cggaaaacac ggggcaattc gaacgtacgc tgatcattgt tgacgaagga gcaagcatcc
    26221 actatgtcga aggttgtacg gcacctactt attcaagtaa cagcctgcat gccgccatcg
    26281 tagaaatctt tacaagaaaa gatgcgtatt gccgttacac aacgatccaa aactggtcag
    26341 acaatgtgta caacttagta accaaacgag caaaagcata cgaaggcgca accgttgaat
    26401 ggatcgacgg aaacctaggt gcaaaaacaa cgatgaaata cccaagtgtt tacttagatg
    26461 gaaaaggtgc acgaggcacc atgctctcca tcgcctttgc aggagcaaac caaatccaag
    26521 atacgggtgc aaaaatgatc cacaatgcac caaatacatc tagctctatc gtctctaaat
    26581 caatttcaaa agacggcgga gaagtaaact atcgaggaca agtaaccttt gccaaaaaca
    26641 gtgcgggttc gatctctcat atcgaatgtg acacgatcat catggacgaa tggtcgaaat
    26701 ccgatacgat cccattcaat gagatccaca acagccaagt ctctttagaa cacgaagcca
    26761 aagtctcaaa aatctcagaa gaacaactct actatctgat gagccgaggc ctgaccgaat
    26821 ctgaagcaac tgaaatgatc gtcatgggct ttgttgaacc attcaccaaa gaacttccaa
    26881 tggaatatgc agtcgaactc aatcgattga tcagttatga gatggaaggg tctgtaggtt
    26941 aataactatt tcattgctcg aaacgttgat attaaagcgt ttcgagcgtt tttttatttg
    27001 tattttaatg gttggctacg tttttggcta cgtttggaat tattcgccca taaattttgc
    27061 aaatcggtca ccagttttct taacagattg tggtgtgaca tgagcataga tattcatggt
    27121 agttttaata tctttatgac ctaatcgttc ctgtacttct tttatcgacg caccactttc
    27181 aaacaataag ctacagtggg tatgcctaaa tccatgtgga gtaatttgag gctccatcgg
    27241 tgtctttttg taaatccagt ctaaccaatc gtttactact tgggggtagt acaacttgtt
    27301 tgtgtttgta gtgaaaagaa actgttttgg tgaattcgtg ttatagccat ataagatcat
    27361 tattttcatt tgttcttgtt gccaaatacg cagttgttta agtgtaaaat catcaagctg
    27421 aatcgttctt gatgaatttt tagttttagg tacttgtaga actacttgat taaactcgtc
    27481 ttgagcgata gttttaccaa ttgttattgt tttattgaaa tagtctatat cttcccattg
    27541 aagcgccaat gcttcgcttt tacgcattcc tgtataagct aataaacgga aaaaagtgta
    27601 cagtttaact gaattatttt ctttagtatt ctgtaaaaac agttgtaatt gatctttcgt
    27661 gtaaaacttc aagggttgtt cttcttcaat ttttcttgga agcaatgttt tagacatagg
    27721 attatcctta cagacttcca ttgctactcc aaatttaaat atttgagcag ttgtttttct
    27781 caagaaacca tattgtttta atgttttgtg ccattcattc acctgttttt ggcaatagct
    27841 aacacttatt ttatccaatc gtaattcccc aaaagcaggt aatatatggt ttttgcaaaa
    27901 acgttgagca acggcaacag aagacggttt tactcttgtt ctgtagttat caatccataa
    27961 ttcatacaac tcttgaaaag ttgtaacatt gattttaaac tcttgttttt ctttaaagtc
    28021 tacaagtagt ctattaagtg ctgtttgcgc ctcagctttt gatttgaatc ttctacgctt
    28081 tgtacgtata tcttttccag tcttgggatc tttccctaaa taagtttcaa atccccaata
    28141 tttttcgcca ttttgtaatt tataactaaa aaatgttgcc atttgattct ctccttactt
    28201 cattattgca ggtagagaag ttatttgaag aatcaattat ttttaaattt atcgtgatta
    28261 tcagttaaaa attttgcgat tatactattt ttctcatatg ggaaattgta ttttttacta
    28321 agatctgaaa taaatttttc tgtttcaaat tggtttttag taattttata aaagaaatcc
    28381 tcgacagatg aatactttga aatatcttta taggctaagt ccatttcgtc taatagctgt
    28441 tttaaagaat caatcattct ttctttttca ccgtatttga aatcaccatt tcttatcttg
    28501 tcttgaagtt tactgttggc tcttttgaaa aatagctctt tagagataga gtgtctttgg
    28561 ttagcgtact cttcaatcag aggattgata ttattagcaa gtatctcatt tagataaatt
    28621 tcaaaatctt ttgagtaata ttttgtaaat atatttttta ttataggatt caataactca
    28681 tagtctttat ctagcgaaaa cgtatcacta tatctttctt gaatgtcttt aaagactttg
    28741 tgaggtattt ctgggaagtc cttaatatat agctcatacc ctatatcgat aaggtatgaa
    28801 gttatatatt cttctaaagt tccccattta atccagtcaa ttgttgaatt agtgatagtt
    28861 gataataatt tcagcttttg tggatttggt aaattggtcc cacgttccca gttggatatg
    28921 gtcgcacgtg gtgaattatc tattttcctt ccaagttctt ccatagtaaa accacatgaa
    28981 aggcgtaatt gtttgattcg ttttcctgct tctgaaggat ttggcttcat cttttttctc
    29041 ctttttattt ttaaagatag tatatcatat ttataaaata aaagtattta aaagtattta
    29101 ctttttatct ggagtatgat actttattct tataaataca aataaataca tttttttacg
    29161 caatttgtat ttatttgtac ttataaaggt agaggagtta tagaataatt aattaaaaag
    29221 gagaggtttt tgtggaagca ataaaattaa tgatttcaga agaacaggag gaaatgtttc
    29281 taaagcagtt ttatcaaatt gctacaaaag ctattgaaaa ggctcaagaa aatgcgggga
    29341 tgacaaggga atatctcaat caaaaagaaa tggcggaata cttaaatgtg agtgaaaact
    29401 ttttaaaaaa tgctgtgaga aatgagggat tgcccgtagt tgaattaggg gcaagaaaat
    29461 tttattcgaa aaaggcagtt aatgagttta tgtttgctcg aatgaaaaga ggggaaaata
    29521 ttggaagatg atgaagtaga aattataaaa aaatgcttta aaaaaagaaa aaaagtgttc
    29581 ccaaaagttt gcagactggg ggaacactca ataataaagt gctgagaaaa ctttatttat
    29641 agctattata tcaaaaaaga aggtgaaaag gtgttttctt ctggaaatgt tgtagttgac
    29701 aaacttagag aaataaattt tgacggaaat gtaatccaca cacatggtac gatcaattaa
    29761 gaaaaaaaac gaaaaaaggt gttgagaagc cctatttgaa tgcaatagtt atcttagcag
    29821 aaattaccta ttggtataga cctaaaaaaa tttttaacga tgatggtcag ctacttggtt
    29881 atcaaaaaaa gtttcttgaa gatattttgc aaaaatcata taagcaatta agcaaaaaaa
    29941 caggattatc agaacgagct ataaaagatg caattgtgta cttagagaaa aaggggatta
    30001 tcaaaagggt ttttagaaat atttattatg agaaaagagc agttacatta tcaaatgtta
    30061 tgtacattgt tttaaatgta cataaattga tagaaattac ttttcctact ttggattgcg
    30121 aaaaaaagga gtatatgccg aaaattcgtc agaggggtat cgaaaaaaag agatatgtct
    30181 ctttaaaaaa aggtagaggt atgtacaaat ttgtatatac gtatacaaag actacttcac
    30241 agaacatatc aaagactact ctcgttatgg aagaagagga tattaatata aagaggattt
    30301 acagtaagat tagtgttctt tatgacgcaa ataacgaaga tggtcgaaaa ttatttcaag
    30361 tgtatcacta tttgagaaac gctaatgtag atacagaaga tatcagaaaa atcattgaat
    30421 atttatctga aaatactcag tatcttattg ctgagtgtat tataaaacaa catgaagcat
    30481 gcttttttca aagaaaaact gaagaagggt tatacgatta tgtaacatat tttttgaatg
    30541 gacttcagaa aagatataaa agtcaatttt tagaaaatgt agagcctata gatcagttca
    30601 aaaaagcttt cgaaatcaaa gagttacctg aaattactat gcataattgg ttgaaaggag
    30661 aagaatcatg attaaaaatc gcttaataga tcaaatgtgg tgtcttgatc aaaatacaga
    30721 tactctcgaa ttaatcgaga gtatctgctt caacacagta gttctcgatt taagagctga
    30781 aaatgacaat tgtgtaactc atatcataat taatcaaaaa atggctcagc agctctctga
    30841 gagcctaaga aaatgggctg aaggagaaaa ctatgaaagc aattaaagaa aaaatcgtta
    30901 gtagaaaaat aaactggtta gcactcagtg tacttgtttt aatgattagc gttgttttta
    30961 caagtaatat tgttgaagct agcattttca attggtttga tgacacaaaa agtcaaacag
    31021 agtttttgaa taattctctt tatagacctt acctaaaaaa atacaatgga gatttcctta
    31081 gtcagttcgg gatttggctt ggatgggctg tggtaaaagg catgtttact gtgactgatt
    31141 cgattcaaaa tatgattcca gatgtgttgg atttgttcaa tttcattgaa agtacagggc
    31201 taaataatgt ttatcaatca gtcataaata caattgtcgt tggattaatg atcctttcat
    31261 tgatgtttgt tggctacaag atgattactg gaaaaggaac aatagattta agatctgttg
    31321 gaatgaatat agtgatgtct gtagcgttaa ttcttttaat gccaacaatg atttctagcg
    31381 gtattcaatt tgccaaaata ttttacaatg atgctactac gattacaaat tcagatgacg
    31441 gagtcgcttg gtcattgata aaacaaggag taacagatct ggcatatatt aataaaacag
    31501 atcaatactc aagcattgat aaaacggagg atcgaaataa gttaacacga aaaaattttc
    31561 aacagacaga tttaacacaa gtgttgacgg ataaagtgat tgataaattg gaaaaagaaa
    31621 atccagctgc ggataatctt cgctatgaat
//
LOCUS       DAFEEZ010000030        31017 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000030
VERSION     DAFEEZ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.030"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            203..1144
                     /locus_tag="LP245_001449"
     CDS             203..1144
                     /locus_tag="LP245_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBL1519374.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1213..1944
                     /locus_tag="LP245_001450"
     CDS             1213..1944
                     /locus_tag="LP245_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBL1519375.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2088..4268
                     /locus_tag="LP245_001451"
     CDS             2088..4268
                     /locus_tag="LP245_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBL1519376.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4288..4770
                     /locus_tag="LP245_001452"
     CDS             4288..4770
                     /locus_tag="LP245_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBL1519377.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            4786..5547
                     /locus_tag="LP245_001453"
     CDS             4786..5547
                     /locus_tag="LP245_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBL1519378.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            5678..7012
                     /locus_tag="LP245_001454"
     CDS             5678..7012
                     /locus_tag="LP245_001454"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBL1519379.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7319..7804
                     /locus_tag="LP245_001455"
     CDS             7319..7804
                     /locus_tag="LP245_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBL1519380.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            7797..8480
                     /locus_tag="LP245_001456"
     CDS             7797..8480
                     /locus_tag="LP245_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBL1519381.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8606..11251
                     /gene="polA"
                     /locus_tag="LP245_001457"
     CDS             8606..11251
                     /gene="polA"
                     /locus_tag="LP245_001457"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBL1519382.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELADKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11296..12132
                     /gene="mutM"
                     /locus_tag="LP245_001458"
     CDS             11296..12132
                     /gene="mutM"
                     /locus_tag="LP245_001458"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBL1519383.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12096..12725
                     /locus_tag="LP245_001459"
     CDS             12096..12725
                     /locus_tag="LP245_001459"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBL1519384.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            12777..13109
                     /locus_tag="LP245_001460"
     CDS             12777..13109
                     /locus_tag="LP245_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBL1519385.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHISDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13421..13912
                     /gene="nrdR"
                     /locus_tag="LP245_001461"
     CDS             13421..13912
                     /gene="nrdR"
                     /locus_tag="LP245_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBL1519386.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            13935..15308
                     /locus_tag="LP245_001462"
     CDS             13935..15308
                     /locus_tag="LP245_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBL1519387.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15308..16234
                     /gene="dnaI"
                     /locus_tag="LP245_001463"
     CDS             15308..16234
                     /gene="dnaI"
                     /locus_tag="LP245_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBL1519388.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16363..16803
                     /locus_tag="LP245_001464"
     CDS             16363..16803
                     /locus_tag="LP245_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL1519389.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            16947..17648
                     /locus_tag="LP245_001465"
     CDS             16947..17648
                     /locus_tag="LP245_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBL1519390.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            17645..18766
                     /locus_tag="LP245_001466"
     CDS             17645..18766
                     /locus_tag="LP245_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBL1519391.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            18781..20013
                     /gene="pepT"
                     /locus_tag="LP245_001467"
     CDS             18781..20013
                     /gene="pepT"
                     /locus_tag="LP245_001467"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBL1519392.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20145..21053
                     /locus_tag="LP245_001468"
     CDS             20145..21053
                     /locus_tag="LP245_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBL1519393.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21088..21360
                     /locus_tag="LP245_001469"
     CDS             21088..21360
                     /locus_tag="LP245_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBL1519394.1"
                     /translation="MDVLLHNLLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            21371..22417
                     /locus_tag="LP245_001470"
     CDS             21371..22417
                     /locus_tag="LP245_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBL1519395.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            22668..25277
                     /gene="clpB"
                     /locus_tag="LP245_001471"
     CDS             22668..25277
                     /gene="clpB"
                     /locus_tag="LP245_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBL1519396.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(25428..26114)
                     /locus_tag="LP245_001472"
     CDS             complement(25428..26114)
                     /locus_tag="LP245_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519397.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(26092..26586)
                     /locus_tag="LP245_001473"
     CDS             complement(26092..26586)
                     /locus_tag="LP245_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBL1519398.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(26606..27826)
                     /locus_tag="LP245_001474"
     CDS             complement(26606..27826)
                     /locus_tag="LP245_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1519399.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            27973..29808
                     /gene="lepA"
                     /locus_tag="LP245_001475"
     CDS             27973..29808
                     /gene="lepA"
                     /locus_tag="LP245_001475"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBL1519400.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(29902..>31017)
                     /locus_tag="LP245_001476"
     CDS             complement(29902..>31017)
                     /locus_tag="LP245_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1519401.1"
                     /translation="FVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVLSDID
                     ETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLS
                     PVLLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEAR
                     PTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNG
                     TITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYI
                     DSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEIS
                     ERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT        10329 a         5554 c         6643 g         8491 t
ORIGIN      
        1 atgttggtga agttcaccaa catcaaaaag tatagagccg tttttctgtg cgaaacagga
       61 aagcgaagtc tttttaattc aaataataat attatgtaaa caaaaaactt tccatgcgta
      121 attatacaca agcaaataaa tcgtcaaatg cgaacgcctt ctttatactg tttaggaacg
      181 aaaagaagga aggaagaaat acatggatta tcaagtactg ctttattaca attatacaaa
      241 aatcgaagaa ccagaggaat ttgccaaaaa tcatttagcc ttttgcaaat ctttggatct
      301 taaaggtcgt attctagtag ctgaagaagg aataaatggt actgtgtctg gaaccgttga
      361 aaacacgact gcctatatga aagcaatgaa agctgatcct cgatttgctg atacgatgtt
      421 caagatcgat ccaagcgaag gacatgcctt taagaagatg tttgtaagat accgtccaga
      481 gcttgtaagt ttaaagctag aagaggacat tgatccaaac caagtgacag gtgcctatct
      541 ttcaccgcaa gaatttaaag aagctatttt agatgaacag acagtggtga ttgatgcacg
      601 gaatgattat gaatatgact tgggacattt tcgaggggct gtacgcccag atatacgcag
      661 ttttcgagag cttccagact ggatccgcga gcacaaagaa gaatttatgg aaaaacgggt
      721 agtgacctac tgtactggtg gcattcgttg cgagaagttt tctggttggc ttgtccgtga
      781 aggattcaaa gatgtcggac agctgcatgg cggtattgct acttatggta aggatcctga
      841 agtccaagga gaattatggg acggcaagat gtatgtgttt gatgaacgga tcgctgtcga
      901 tatcaaccaa gtagataaac aaatcgtcgg tcgcgactgg tttgacggaa caccatgtga
      961 acgatatatc aattgtagca atcctgagtg caatcgtcag attcttgctt ccattgaaaa
     1021 tgaagaaaaa catttaggag catgtagcat agagtgtgcg aaacatccgc gcaatcgcta
     1081 tgttcaagac catggaatct ctccagaaga agcagaactg cggtttacag ctttaattaa
     1141 atagaaaaca atagttttga ttgtcgacca tttccaatat gcgctatact agcgttgagg
     1201 atggtgatcc acatgaaatc attgatttat gctattgggg atgtccatgg caaacatgag
     1261 ctttttgaaa aacttattca ctattatgat ccaaagatcc atcagcttgt tttattaggg
     1321 gatctcaatg atcgaggtcc tcgtacaaaa gaatgttttt tattaggaaa gcaattagtc
     1381 gaagaaacag gagccattta cctccgggga aaccatgaag aatatttttt gcaatttctg
     1441 caatcaccgg aggactggta tgcgccttat atgagaaatg gtggaaaaga aacgtttgaa
     1501 agcctgattc acccaggggc atcggaggaa tactccccaa ctgaaatctc gatgatgatc
     1561 caatcgagat attcagaact gattaaattt ttagtccagc gccccttgta ttatgaatgg
     1621 gaaaattatc tttttgtcca tgccggtgtg gatttgacaa agaaagactg gcgtaagaca
     1681 agtctaagag actttatttg gataagggaa ccatttcatg aagggaaaaa caatacaggt
     1741 aagacaattg tatttggaca tacgattaca ccaatgctcc atggagatat gcagacaaca
     1801 gacctctgga ttcaggatca taaaatcgga atggacggtg gggctgtatt cggagggtca
     1861 ttgcatgggg ttgtttttga caaggaaggt attcttcaag atattgaata tcagaacaac
     1921 gaaggacctt ggcatggaat ctgactaatg gaaagaatga aggagctgtg actttgttgc
     1981 ggctcttttt atttttatag agaatattgt ttctttcagt agtttaaccc aggataaaaa
     2041 gtatgataga ataaagaagc aatttttagc agaaaagagg cattttaatg acggaaaatt
     2101 tgaaccagac gatcattcag cttgtacaaa aagaactttc agactatcgt cctaagcagt
     2161 tgactactgt acttaatttg ttaaatgaag gaaacactgt tccttttatc gcgcgttacc
     2221 gaaaagaaat gactggaagt cttgatgaag tccagattcg tgaaatcgaa gagcggtatg
     2281 cctatcttga aaacttagaa aaacgtaaaa ctgaagtgat tcggctaatc gatgaacaag
     2341 ggaaactgac tcccgagtta gaagcagaaa tcacccaagc cgtgaaaatg caacaagtgg
     2401 aagatttgta tcgtccatac aaacaaaaac gacggacaaa agcaacgatt gctaaagaaa
     2461 aaggacttga accactcgcg aagtggctga tgcagcttac agatggagag gtgcaatctg
     2521 aagcagaaaa atatattgac aaagaaaaag aagtctcttc tgccgaagaa gcgttgcacg
     2581 gtgctcatga gattattgct gaacaagtca gcgataatgc aaaatttcgg acttggattc
     2641 ggtcttatac gtataacaaa ggtatgtatg tcagcaatgt caaggatgag caagcagatg
     2701 aaaaaggcgt atatgaaatg tattatgact ttgcagaacc cgtccataaa atggtttctc
     2761 atcgaatatt agctactaat cgtggagaaa aagaagatat tctgaaagta ttctttcaag
     2821 tagatgaagc agcaatttta gcttacttgg atcgccaaat agtcaaaaat cctgcctctc
     2881 cttcttcttc attcgtcaga gaagcctatc aggatagtta taaacgcttt attcagccag
     2941 caatcgagcg agaactgcgc aatgaattga ctgaaaaggc agatgagcaa gcaatcgcta
     3001 ttttcggcga aaacctccgt aatcttttgt tgcaaccgcc actaaaaggt aaagttgtcc
     3061 tgggatttga tccggcttat cgtactggat gtaaactagc agtcgtagat gcgacaggga
     3121 aagttttagc aatcgaagtt atttatcctc ataaacctgc agcgcaagca aaaagagaag
     3181 ctgctggacc agcttttatc caattaatta ataaatatca agtagatatg gtagctatcg
     3241 gaaatggtac agccagtcgg gaatctgaac tttttgtggc tgagcagttg aaatccgccg
     3301 accataaaac ctattacgct atcgtcaacg aagcaggcgc ttctgtttac tccgctagcg
     3361 aaattgcacg aaaagaattt ccgcatctac aagttgaaga aagaagtgct gtttctattg
     3421 cccgtcgcct gcaagatcct ttagctgaat tagtcaaaat cgatcctaaa gctgtcggag
     3481 taggccagta ccaacatgac gtttctcaaa aacgtttggc tgaacaattg gattttgttg
     3541 tggaaacagc ggttaaccaa gtaggtgtgg atgtgaatac agcaagcccg cagctcttgc
     3601 agcatatatc aggattgaat aaaacaactg cccaaaacat tgtcatttat cgtgaagaaa
     3661 acggagaatt caccgcacga actcaattga aaaaagtgcc acgcttagga ccaaaagcat
     3721 atgaacaagc aatcggattc ttgcgagtcc ctggtgggaa aaacattttg gacaacacag
     3781 gtatccatcc cgaaagttat tctattgcaa aagaaatatt aacttcagtc caactttcag
     3841 aaaaagagct tggtacagaa gaagcagtag aaaaattgac acgattatcc gtagagaaac
     3901 tggctgaaag cctatcagtc ggagaagaaa cgttagccga tattttagct gggctgacac
     3961 aacctggacg agatatgcgt gatgagatgc cagcgccctt attacgtaca gatgtattga
     4021 gtatggaaga cttgaaacca gggatggaat tgactggaac ggtccgtaat gtcattgact
     4081 tcggcgcatt tgttgatatc ggtgtgaagc aagacggact tgtccatata tcgaaactca
     4141 gcaaaaaatt cgtcaagcat cctacagatg tcgtgtcagt aggagatatc gtaacagttt
     4201 ggatagaaca agtcgatacg aaaaaaggca gaatcagttt gacgatgctt tccccttatg
     4261 aagagtaaca atgaggagta acaaaaattg acacaagaag aactgcagca gttagtagaa
     4321 gagatatcat taaaaagctt ccagcttcct ttcaagcacc aagcaatgtt caatccacgc
     4381 ttacgtacaa ctggcgggcg ctatcattta aacgatcatc atttagattt taatgcgaag
     4441 ctatttgaag agtcagacga agagacgatt gcaggaatca tcaaacatga actttgccat
     4501 tatcatcttc atctagctgg aagagggtat cagcataaag atatggattt caagtatctt
     4561 ttgaaaaaaa caggagggtt gcgctatgca ccagccttga cgaagaaaca gataaagatg
     4621 gagtattatc gatgccaaga ttgttctgcc acgatctgcc gcaagagaag aatcgatgta
     4681 cgcaaatatc gttgtggaag atgtcatgga gaaatcaaat ggattgagac aaaaagagaa
     4741 gactttaatg aagcacaaaa aatcagatga aaggatagaa ggcctttgga aaaaagtgag
     4801 cagaggaatc taaaagactg gaatcagcta ttaaattttt tagccgcacc tgaagaggga
     4861 aattttgagg aactgacggc acctacactt attttagctg gaaactgtct tcctatctta
     4921 gctgataaag cagcacaaat gtatttaaat ggccaagtag atcaattgtt tttggtcgga
     4981 ggggtggggc atgcgactag aatcctttat gagaattttg aaaagcaagg atttcatttt
     5041 gaagatggca tgagtgaaag tgaaatctgt cgtcagtatc taaaagaagt ctatgatttg
     5101 cccgataagg cttttctgat agaatcgaag tctacaaatt ctggagagaa cgccactttt
     5161 tcactggaga ttcttcattc cttaggagct gtaccagaaa aaatcttatt gatgaatgat
     5221 ccgacactgc aacgcaggac tcgagcaact tttgagaaag tatggcaaaa tgaacaaact
     5281 attttcgcga atgctgtgcc atttgtgccg gaaatccttc acttttctga agagatcatc
     5341 tttacagcaa aagaactgaa tcatcaatgg cctaaggaat atttccatgc gctagtatta
     5401 ggagaaatgg aacgtctcca tgacgatgag aacggctatg gtccgaaagg aaaagatttt
     5461 attcctcaca ttgatatatc agaggaagtt tggtcttctt acaccagaat taaagagtca
     5521 ataaaaacgg atttttctcg tacttgacca ttttagcaag cgaatcctcc tttccaaata
     5581 aatttggttg aaattttcaa tcgtttataa gataatgagg agcgtgttga atgtaatagc
     5641 taaaagaatg gacgctagat aagagaagag gattcaaatg gaaaatcaaa ataaattgta
     5701 tcattttgtt ggtatcaaag gttcaggaat gagctccttg gctcttgttt tacatgaaca
     5761 aggtctaaat gtccaaggat cagacattga aaaatatttc tttacacaaa gagatttaga
     5821 aaaagcaaat atcacgattc tgccatttaa cgcagataat gtaaaaccag ggatgacgat
     5881 cattgcagga aatgcatttc ctgattcaca tgaagaaatc cagcgagcaa aagaattagg
     5941 tttggaagtg attcgctatc acgactttat tggtcatttt atccaaaatt atacgagtat
     6001 cgctgtaaca ggctctcacg gaaaaacaag tacgactgga ctgctctctc atgtattgag
     6061 tggtgtccgt ccaacaagtt atctaattgg agatggaaca ggacatggtg atccgcaagc
     6121 ggaattcttt tcatttgagg cctgtgaata tcgccgtcat ttccttgcct attcaccaga
     6181 ctatgcaatc atgaccaata tcgattttga tcatccggat tattatacaa gtatcgacga
     6241 tgtatttaca gctttccaaa caatggctgg acaagtgaaa aaagctattt ttgcgtatgg
     6301 tgacgatgct tatttacgca aattaaaagc aaatgtgccg atttattatt atggtgtcac
     6361 agaaaacgat gatatccaag cacgaaacat cgaacgcaca acttctggtt ctgcttttga
     6421 tgtctatcat ggggatgaat ttgttgggca cttcactgta ccagcattcg gtaaacacaa
     6481 tatcttaaat gctttaggtg ttattgcagt agcttatttc gaaaaactgg atctgaaaga
     6541 agttgcagaa gaaatgctga ctttcccagg agtaaaacgt cgattcagtg aaaagatcgt
     6601 agcagacatg accgtagtcg atgattatgc gcatcaccct gcagagatca aagcaacgat
     6661 tgatggcgca cgccaaaaat atccagataa agaaataatt gcagttttcc aaccccatac
     6721 gtttacgcgt acgattgcat tgatggatga atttgcagaa gcacttgatt tagctgataa
     6781 agtttactta tgcgatattt ttggttcggc tcgggaagaa caaggaaacg ttaagattga
     6841 agaccttgga gcgaaaatca aaaaaggtgg agaagtcatc aaagaaaata atgtatctcc
     6901 attgttagat tatcatgatg cagtagtaat cttcatgggt gctggagatg ttcaaaaatt
     6961 tgaacaagcg tatgaaaaac ttttaagcag cacgacgaaa aatgtactgt aatacaatta
     7021 ctgcagtgtc cttataaaaa tagaaagagg gggagtggca aaaatcttgc caagccccct
     7081 tttttgcaac ttatgataaa cggtgttcaa aagcttgcat ctgcggtaat aagcccaatc
     7141 aaatcaaaaa catgagaagc tgttttttct tggctgttct tattatttga tgcaggacag
     7201 ctttttcacg acctctgtaa actataggaa tctgttaaat caagggagca gaacttgcct
     7261 tttacgctac ttttggtaca ataatgtatg attaaaaata aactggaggg tttctatctt
     7321 gaacataggt aagccgagaa aactaggaaa aacaataaat gaaatcgagg aaggcgactc
     7381 gttatcctta acagaatcta ttgaagataa ccagcttttg ctgtatttgg gattgacgaa
     7441 tgatgcaaat cctttgtata tccaacatga ctttgcacaa aaaacagaat atcaacagcc
     7501 aatcgttcca tcagtgatgc tgatggggat catcacaagt gcaatttcaa agcatcttcc
     7561 tggaccagga tcacatgttg tcaatttttc tgtcaatttt attgaaccgg ttttccatta
     7621 tgaaacactg acttttcagt ttgaggtcat aaaagtagat aagatgaagg atgtggtgac
     7681 gatttctgta gaagcggaga atacgaacga agatcgtgtg ttggatgctg tcgttatggt
     7741 ccaaccgcca caagttcctg aattggaaat agcaatcgaa agtgaaggtg aattgaatga
     7801 ataatccaag tacatcaatg tcaggtatca atcgttttta tgcaaaagtt tatggatttt
     7861 taggtatggg acttgccctt agtgcagtca cttcttactt ggctctttgg gtatttcctt
     7921 tgcaattagc aacttttatc aataattttc cactaggctt tgtgggtctg tggatcgttg
     7981 aactgatttt agtaatggtt ctaggcgtaa aagcacaaaa gaatccgagc ttagcaatcg
     8041 gtggatttat tgcctactct cttttgaatg gcataacatt agcggttact cttgcatact
     8101 acgatattgg aacagtaacg caagctttct tgacagctac tttgatgttc atggggatgt
     8161 ctgttgtcgg agtaacaaca aaaagagatc ttagcggggt tggaagagca ggacaggcag
     8221 ctttaatcgg agtgatcatt gcactagtct tgaacatctt cattttgaga agtagcgtag
     8281 ttgagctgtt catctcccta ctgttagtcg tcatctttgc agggattaca gcttatgata
     8341 accaaagcat ccgtaatatc tatgtccaga caaacggaac agcacatagt ggaattgctg
     8401 tattcatggc attgaagctg tatttggact ttatcaactt gttcttggcg tttctgagaa
     8461 tctttggacg gaacaactaa aaaagaaaaa aattcatcag ttggggctat accgaattat
     8521 ttggtatggt cccgcttttt cttttcgcat tccgcaggat tctttgttag aatgaataag
     8581 aactttacag taaggagtta agaagatgac aaaaaataaa ttattactcg ttgatgggaa
     8641 cagtgtggct tttcgcgcat tctttgcgct tcacaattct cttgaacgtt tcaaaaatag
     8701 aaacggtctt catacaaatg caatctatgc attcaatacg atgtttgaaa atgttatgca
     8761 aaaagagcaa ccgactcatg ttctggttgc gttcgatgca ggaaaaacga cttttcggac
     8821 agaaatgtat gcggagtaca aaggtggaag atccaaaaca cctggcgaat tcaaagaaca
     8881 aatgccatat atacgtgatt tgttgacagg actaggggta cagtattacg aattgcccaa
     8941 ttatgaagca gatgatatta tcggtacttt ggcagaaaaa gtagacaaag atcaatttga
     9001 tgtcgtcgtg ctttcaggtg atcgggattt gactcaatta gctagtaaag aagtaaaagt
     9061 ggatatcact gtaaaaggtg tcagcgatat cgaaagctat acaccagaac atgtagcgga
     9121 aaaatatgat gggttgacgc caaaacagat tattgacatg aagggactag ccggagatgc
     9181 ctctgacaat atccccggtg tgactaaaat cggtgaaaaa acagctatca agctattgaa
     9241 acaatatggc tcagtcgaag gaatttatga acatatcgat gaaatgaagc aaagcaaaat
     9301 gaaagaaaat ctgataaatg acaaagagca ggctttctta tcgaaaaaat tggcgaccat
     9361 caatacttca gcgcctgtgg atgtctctat cgactcattg aagtatgaag ggaaaaatct
     9421 cgataaactc gttccgtttt ataaagaaat ggatttcaat cagttccttt ctaaattgaa
     9481 tatcgtagaa gaagaagtaa aaatggatga tattttgttt gaagtcgttc atgaattcaa
     9541 agaggaaatg tttactacgg atatggcgtt gtacgtggaa atgatgggcg acaattatca
     9601 tacagaggaa atcgtcggag tagcgtgggg gacagaaaag aaaatttatg tcacgaacga
     9661 tctatctgta ttcgaaaacc gagcgttcca ttcttggatc actgatccga ctcggctgaa
     9721 aaaagtatat gatgcgaaac gaacttatgt tgctttaaac cgctatactg gaaaaacgaa
     9781 aggaatcgat tttgatgtct tgctaggtgc ataccttctc gatacgaatg aaaaaagcac
     9841 agatatcgaa ggaatagctg ctcattacgg atacaacgat atccaatcag atgaagctgt
     9901 atacggcaaa ggggcgaaaa aaggtttacc agaagaagag gaactctttt ttgctcattt
     9961 agcgcgaaaa gtagctgcaa tcaatgcgtt gacaccaaaa ttgagccaag aactggcaga
    10021 taaaaaccaa gaagatcttt tccggaaaat ggaactgcca ttgtctatca ttttggcaga
    10081 gatggaaata agcgggatca aagtagatgc gactcgctta caagaaatga agggcgagtt
    10141 ctctgctcgc ttaagagaga tcgaacaaaa aatctacgaa gaagccggcg aagaattcaa
    10201 tttgaattca ccaaagcaat taggagtgat cttatttgaa aaaatgggat tacccgttat
    10261 caaaaaaaca aaaactggat attccacagc cgtagatgta ctggaacagc ttcgtgaaca
    10321 agcaccaatc gtagaggata tcctcaccta tcgtcaaatt gcaaaaattc aatctaccta
    10381 tgtcgaggga ctgctgaaag tgatccaatc agatggaaaa gtgcataccc gttatgtcca
    10441 gacattgacc caaacaggac gattaagctc tgttgatcct aatttgcaga acatcccgat
    10501 tcgattagat gaagggagaa agatacgtca ggcatttgtt cctagagaaa aagactggct
    10561 gatttattct tctgactatt cacaaatcga gttacgcgta cttgcgcata tctcaaatga
    10621 tgaacatttg aaagctgcct tcctagaagg tcaagatatc catgccagca cagcgatgcg
    10681 tgtatttgga atcgaaaagg cagaggatgt cacaccaaat atgcgtaggc aggcaaaagc
    10741 agtgaatttt ggtatcgtgt atggcatctc tgattacgga ctttcacaaa atctaggaat
    10801 cagccgaaaa gcagcacagc aatacatcga tacgtacttt gaaaaatacc caggtgtcaa
    10861 agaatatatg gaaagaatcg tacgcgaagc aaaagaccaa ggctacgtcg aaacgctgta
    10921 tcaccgccgt cgatatctgc cagacatcaa ttcaagaaat tacaatatcc gttcttttgc
    10981 ggaacgaaca gctatcaata caccaatcca aggaagtgct gctgatattt tgaaaatcgc
    11041 gatgatcgaa ttggataaac gattaaaaga aacaggtctt caagctacga tgctgttaca
    11101 agttcatgat gaacttgtct tcgaggtacc ggaaaaagaa cttgaatcat tagataaatt
    11161 ggtgaaggaa gttatggaac aagctgtttc tcttcatgta ccactgatca ctgacagcag
    11221 ttggggaaaa acgtggtacg aagcaaaata aacattgttt aagacagagc aatataatga
    11281 aggtgaaaag aaaaaatgcc agaattacca gaagtagaaa ccgttcgtaa aggattggaa
    11341 cggttagtag taggaaaaac gattcaaaaa gttcaggtct tgtggcccaa gatcatcgag
    11401 caaccagaga cacccatctt tgaggcttct cttgttggcg aaaccatcca atccattgga
    11461 cgtagaggga agtttttaat ttttcatctc gatcattgtg aactgatctc acacttgcga
    11521 atggaaggaa aatatcaatt tacgaaagaa aatacaccaa tcgataaaca tacgcatgta
    11581 cttttctttt ttgaggatgg aagccaactt cgctacaacg atgtacgaaa atttggtcgt
    11641 atgacaatcg tcgaaaaagg agcaagtgca acttaccgag gaatcatgaa attgggacct
    11701 gagcctttgc cagatagctt cttattagca gatttcgcaa atggactgaa aaagtcccac
    11761 aaagcaatca agccattgct gctagaccaa cgtctagtga ctggtctagg taatatttat
    11821 gtagatgaag cattatggga agcgaagatc catccagaac aaccggcgaa cacactgcgc
    11881 cccaaagagg tagaacaatt acgtctatcg atcattgatg ttttggatcg tgcaatagaa
    11941 gccggaggta ccacgattcg cagttatttg aatgcattag gagaatcagg cggatttcaa
    12001 gtagcactgc atgtctatca gcaaactggc aaaccatgta tacgttgtgg aacgccgatc
    12061 gtgaaaacaa aagtggcaca aagggggacg cactattgtc cgaattgtca aaggctaaaa
    12121 atcgcaaagt aggatttgtt ttaggtttga cgggtggaat agctaccggt aaaagtacgg
    12181 cagccaaagt ctttcagtct catggatttc ctttgatcga tggcgatgtg attgccagag
    12241 aaactgttga gcctggaacg cttgctctga ggaaaattgt atcagtgttt ggccaagagg
    12301 tattgcagcc tgatgggcaa ctagatcgag ggaaacttgg gatgattgtt tttccatcaa
    12361 aggaaaaacg gcaaaaactt gatcagctat tagatccgtt tatccgaaaa gcgataaaag
    12421 atcaaatcgc ctctctaagt tccaatcatc ctttagtaat tgtagatatc ccattgctct
    12481 acgaaggtca ttatgaccac tatatggatg cagtagctgt cgtttatact acgccagaaa
    12541 ctcagcttca gcgtttgatg aaacgtaatc aactgacgct agaacaagcg cagcagagaa
    12601 ttagtagtca acttccaatc gaagaaaaaa agcagcgtgc ggatattttg ttcgacaaca
    12661 atggaacaaa agaaaaactt gtgggacaaa tcgaaaattg gctttttgct aatcgctttc
    12721 tttgagtatc tgtgtcaatt ttgctatcct gagtatatag aaagtgaggg atagcgatgg
    12781 gatcattaaa aaatcaaaag gataaagtcg taggtaacgc aaaagaaaaa atcggcgaga
    12841 tgctcaataa agaaaatcta atcgatgaag gtcgtacgca atcagaaaca gcagaagaaa
    12901 aagaaaagca gtaccaagca agaatcgatg aaatagaaga ccagcaggca gaagaagaag
    12961 cgaagcggca agatttgact caagaacgaa aaaatccgac acctgatcgt agtaaaacac
    13021 cgctcccaga aagtgaccac atttccgatg agcaaaaaat cgaggaacag cgaatgaaac
    13081 actatacagg aatcgaagag aagttataaa atagtaaaaa atcgagatgt gacttgaagc
    13141 agatgagaag gtgttcatct gcttcaagtt ttttgtgcta gatgactaaa tcagcttttg
    13201 tgtaagttat ttctcagtaa tcaaggtgat cagtattgga aaattgaaat ttagtaagga
    13261 caggggacac aattacgcat gaaagtagaa aaaattgttc ttatatccgt gttttttggg
    13321 taggacagtc gcgtttgtga tttgtttcgt gttataatac aactagttgt aaagaaagac
    13381 acatccttta tataaaatgc gatgcaagag gtgagacaaa atgagatgtc ccagatgtca
    13441 acataataat tcacgagtaa tcgacagccg tcaagcagat gatggacgtg cgatccgtcg
    13501 ccgtcgcgaa tgtgagaatt gttcgttccg attcactaca tttgaacgaa ttgaagctgc
    13561 tccgttatta gtaatcaaga aaaacgggga acgcgaagag ttcaatcgcg ataaaatttt
    13621 aagaggactc atccgttcag cagaaaaaag acctgtagct atggaacaaa tggaacaaat
    13681 cgtcaaccat gtcgaaaacc gcgtacgcag tctcggagaa aacgaagtat cgacgaatct
    13741 aattggtgaa tatgtgatgg aagatttagt tgatttagac gaaatcgctt atattcgttt
    13801 tgcaagtgtt tatcgccagt tcaaagatat gtctgttttc ttaaaagagt tgcaagatat
    13861 cgtggataaa gcaaaagaaa ataataaaga gaataataaa gaaaacaatt aagaaacaaa
    13921 aaggaggcat ttccttggaa aatgcttgga aagagcttca accaaaaaat atttaccaag
    13981 gaagaaaagc ggctccgctg agagaagaca gcaagaacgc cttgctgtat ctttatcagc
    14041 cactaatcgg cggagaagcc ttgagtatct atttcaccct gttatcagaa atctctcaag
    14101 aatctggcaa aggtcctgaa gggatgcatg cagatctgct tagtagtcta ggctgcggta
    14161 tcccgcaatt ttatgatgca agaaaaaagc tagaaggaat cggcttactg gatgtttatt
    14221 ttaaagaaga tagtgatctg ggacctcgtt ttatttatga gctgttagaa ccactcattc
    14281 ctaaagcatt tttcaaagac tctgttctgg cttttcttct tctggaaaaa gttggtgaac
    14341 gacgattcca gaagcttacc caattctttg aacctaaaag gcatacagca gagggatatc
    14401 aaaaaatcac aaaaaaattt ttagatgttt atcgcttcaa tgaagcagtg tacgctgcta
    14461 atcaagaaaa catcgaatcg ctgaataaat cttttgaaga atctgaatca gtagcattac
    14521 ttgaagcaga ttcgacattc gattggcagt ttttgaatga ttggctggca aaaaaacata
    14581 ttgcaagtct tgatgatcca atcatcaaac aagtcgacat gtatcatcag ctttacggtt
    14641 tcgatgaatt gacacttggc gaactgatca gtcaatctta tgactttagt gaacaaaaag
    14701 tatctgaaaa agaactgcaa aaagccattt tggcaatgca gagacgtccg gtgaagcaaa
    14761 caaaagaaac agttgcggtt tctgaaaaca gtaatgaacc ctcgtcaaac gaacatttga
    14821 caaacgcagc gcttcagctg ataaaagaag cacagagcat tccaccgatg aaatatctgg
    14881 aagcaatcaa gtcagaaaaa ggcggatatg tttctaaaca agaaaactgg ttactgcaag
    14941 atcttgtttc tcaatcaggt ctttccagta gcgtgatcaa tgttttgctg aattatgtac
    15001 tagtgatcaa gaataatgct agcttaaatg ccagttatgt aaatacagtg gcaaatgaat
    15061 gggcacaaaa gaaaatcgcc acagcagaag aagcgatcca gcacattcgg caaataagta
    15121 atcaagcaaa acaatcaaaa caaaagaagc aaacaaatta tcaaactggc aagcgaaatg
    15181 ttcgacggga aaagcttcct gattgggtca accagccaaa agatgaaaaa cagatcagca
    15241 gcgagaaaaa agcagagatt gaccgccgtt ttaaagaata cctggcaaaa aaggagggtg
    15301 atatctagtg gaagacgtag gcaaagaatt gaagaggatc atcagcaaac gcaattatca
    15361 agaaaagtat gctgaaatga tcgctgaagt cttaaatgat gcggatgttc aagcttttct
    15421 aagcgcacac caagaagaat tgacacaagc ggatattgaa aaaagttacg ctaaattgta
    15481 tgaattcgtg caagaaaagc gtaaatatca aaaaaacgat ccaacgatga tcgctcccgg
    15541 ctatgagccg aagctgacgt tgaattttca ttatgtggat gtcacttatg taccaacgga
    15601 agcattgtta gcacggcaaa gacaagaaga aatcagaagc cgagtaaaag caatggatat
    15661 gccaaaagat attcaatcgg cttcttttga aaactttgaa cgtacagatg gacgaggata
    15721 tgcgagctta gaagccctag attttgtaga gaaatatact gctgatccaa aagggtatca
    15781 taaaggactg tatctagtag gaagttttgg tattggaaaa acatatttat taggagcaac
    15841 agcgagagaa ttagcgattg ctggattcac cacgacgcta gtccattttc cgacatttgc
    15901 cgttgagatg aaacaggcaa tcggaaaaga tcaagtggca gaaaagttag atgcagtgaa
    15961 acgttcacct attttgatga tcgatgacat tggtgcagat gcgatgagta gttggatacg
    16021 agacgaagta ttcggtgtta tccttcaata tcggatgcag gaacagttac caaccttctt
    16081 ctcatcgaat tttacaatgg atgaattgga acagcatttg tccgtcactc aacgtggaga
    16141 tgaagagccg ctaaaagcga aacggataat ggaacgcata cgttatttga caaaagaaat
    16201 cgaaatgact ggtcgcaacc gacgcaatgg ttgaacagtt gacaagtcca actgacattt
    16261 gacctagtag taaaagcagg tcagcgaatc attatatgga cagaaatgac cggagacaat
    16321 caccgcaaca agtaatgcag aaacttaaac ggaggatttt ttatgagggc tattttttct
    16381 agtatatctg tagttggtct attttttctt ttagcaggct gcggtagcgc agatagcaac
    16441 acaggttctg ttgattcgat tgatgcgggt caaacagtaa aaacaagcag tacgaaaacg
    16501 gagagacaaa gcatatttgt cggaacgatt gaaagtatta ctcaagtaga agcagaagaa
    16561 gaaacgcttc agttgaaact cgtcgatgtc atggccaaag aagatccagc gaatatggga
    16621 acgtcattca gcaatgacgg agtgatctta aatgctactg ctgaaaaaat aagcgtggac
    16681 ataaatgaat tgaaaatcgg tgacaaagtc caatttacat tagttgagat gccgatcatg
    16741 acgatgtcta tcccaccgca agttcctgga gattcgatta ttgatgtttc attgaacaaa
    16801 taaccaataa cattttttca aaaataagaa aatgttgttt tatagaacga aaaggtatat
    16861 tttttaagga gatatgggaa tttttttatt cctagtctcc ttattttatt tggaaaatgc
    16921 tataattatc tagaaggagt gaagctatga accatttaga tttatctcag cgcttagccg
    16981 cagtgggtga ctttgtccct gaatccgctc gtttagcaga cattggatca gatcacgctt
    17041 acttacccgt tgcattgata ttaagaggaa aaatcgaata tgcagttgct ggtgaagtcg
    17101 ttcaaggtcc ttatgaatca gcacgtaagc aagtcaaaaa agatggatta gaagaccgta
    17161 tcaccgtacg ccttgcaaat ggtctagatg ctatccagcc acaagatggt attacagctg
    17221 tcacgattgc gggtatggga ggttcactga tccgagatat cctagaagct ggcaagttga
    17281 atcaacgctt aagcggacaa gaacgtttga tccttcagcc aaacatcgga gagcgtacat
    17341 tacgatcttg gctgcaagaa aatcagtata aaatccaatc agaaaaaata cttgaagaaa
    17401 ataaaaaaat atatgaaatc attgtagccg aaaaagaaca aaaaccagtt acttacaatg
    17461 aaatggagct gatgttcggg ccatttctgc ttgaagagaa aagtgagatc ttcaaatcaa
    17521 aatggacaag agagcttcaa caaagaaaag ctatccgtga acagctcaaa caagcagcta
    17581 atcaagaggc acgtcaaaaa caaatcgagc aggaaatcca aatgattgag gaggttttaa
    17641 agccatgaca atcagcggac gcactttcat ccaaaagttt gaaagctatt gtcctcagtg
    17701 gctagctgaa gaaggagacc cagtcggact gcatatcgga acattggata agccaatcca
    17761 acgagtaatg atgacattag acgttcgtcc agaagtggtc gaagaagcaa tcaagaaaaa
    17821 aatcgatttg ctgattgcta aacatcctcc aatctttcgt cctgtaaaac ggctggttac
    17881 tgatcagcca caagaaaaaa tgtatgcaga tttgttgaaa catgatattg ccgtctatgc
    17941 agcacacacg aacatggata ttatttggga tggactgaat gactggtttt gtgaacttct
    18001 cggtattgaa gtggagagtt atttagtaaa gactcatgag attcattata aaaaactggc
    18061 cgtttatgta cctgtggatc atgcacagaa aatgcgtgaa gtattagctg cagctggtgc
    18121 tggtacacaa ggtgattata ccggtacaag ttttacctcg attggacacg gtcgatttac
    18181 tccggaagct ggtgcacaac cagcgattgg gaaagtaggg aagacagaac aagttcaaga
    18241 ggcaaaagtt gaggttattt tgccggaaac tatcgaaaaa caagtgattc aagccatgcg
    18301 gtcagctcat ccttatgagg aacctgctta tgatcttttc gctatagatg aaccagtcga
    18361 aatgtttggg ttaggacgag taggtgaatt gccgcaagaa atttctatag aggcatttgt
    18421 agaacaagta aaagaagcgt tccaactaga tggactgaga atagtccagc caaaaaatgc
    18481 aaaatcctct gtgaagcgca ttgcgatttg cggtggaagc ggtgaaaaat tttatccgca
    18541 agcaatcgcc caaagagcag atgtctatat cacgggagat atctattatc atacggctca
    18601 tgatatgcaa agcgctgggt tgattgcaat tgatcccggt cattatattg aatcgttatg
    18661 caagcaacga tttatcgaga aatttgaatc ttggaaacaa gaagaaaatt gggatattaa
    18721 ctttttcgtt tctgaaacaa atacaaaccc atttcaattt aattaaaagg agagaatact
    18781 atgtacgaaa atcttttgcc acgtttttta cgatatgtca aaacagaaac acgctccgat
    18841 gcaacaagca aaacgactcc atcgactcag acacaagttg cttttgcgca agaattgaaa
    18901 aaagaattag aagagttagg cttagctgat gttttctata atgaagataa cggattcgtt
    18961 atgggaacat taccaagcaa tgttgatcat gaagtgcgtt ccattggatt tatttcccac
    19021 atggatacag cagattttaa tgcagtagga gtcaatccac aaatcattga aaactatgat
    19081 ggcgagtcta cgatcgtact agatgcggaa gaacgctata cattgaatac aaaagatttt
    19141 ccaaatttga aaaattatga aggccacaca ttgatcacaa cagatggcag tacattactg
    19201 ggagcagatg acaaatcagg gattgcggaa atcatgactg caatggagat cttgatcaat
    19261 aatccttcta tccctcacgg taccatcaaa gtggcttttg gtcctgatga agaaatcggt
    19321 gtcggagcgg ataaattcga tgttgagcaa ttcgatgtag attttgctta tacagtcgat
    19381 ggtggtcctt taggtgagtt gcagtatgaa acgtttagtg ctgctcaagc aaatattacg
    19441 atccaaggga aaaatgtaca tccagggacg gcaaaagata caatgatcaa tgctctacag
    19501 ttagcaatcg attttcataa tcagcttcca gccgatgaag ttccagaaaa aacggaagga
    19561 tacgaaggtt tcttccattt gatggcattg gatgggaatc ctgaagaagc ttctatgagt
    19621 tatatcattc gcgatcatga tcgtgaaaaa ttcgaagcac gcaaagcaca aatcacacat
    19681 atccaagaag agttgaatca gcgatttgat caagaacgaa tcaaagtaga tatgtatgat
    19741 caatattaca acatgaaaga aatcattgaa aaagatatga gcatcgtgga attagcgaaa
    19801 caagcaatga tcgagcttgg tatctctcca gtgatcgaac cagttcgtgg aggaacagat
    19861 ggttcaaaaa tctcttacat gggtattccg acgccaaatc tatttgccgg aggagaaaat
    19921 atgcacggac gattcgaatt tgtttcttta caagtaatgg aaaaagcaac agacgtgatt
    19981 gtaaaaattg cagaattgaa cacaaagagt taaaatcgaa aaagaacagc ttatgacaag
    20041 gcgttcgtcc caatgatgga atgtcatctg tctaaggcta aagggcagga caatggaatt
    20101 ggttgtcccg ccctcttttt tgaagagtaa ataggaggta aagaatggaa aagctgctag
    20161 ttttttataa caaaagttca gggaaagatg agggtgagaa attagcacgc tggtttcaag
    20221 attatgtaaa agaaaagcag ccagaattat atgtagaact agctgaaact ggcccatcga
    20281 ttgatgatgc ggaattagtc aagaaagcag aagccataga agctgatact ttagtaatta
    20341 taggtggaga cggcacgatt catcatatcg tccaagcgtt ccaaaaaaca ttatctcaat
    20401 accatgtcgg attacttcca ggtggaactg tcaacaacct tgcacgtgtt cttgagattc
    20461 ccctcaaaaa agaagaagct gctgacgtga tcctggaagg caatgtacgg aaaatagact
    20521 atggtcaagt caatgatgaa gtcattatct ctacactgac aatcggaatc ttagcagata
    20581 cagcagtttg gatcagtcaa gaagaaaaac agcgttacgg ctcgtggatc tttatcaaga
    20641 agttttttaa gttattgctg aagaagaaaa aatatcattt ggatttagaa acagacgagg
    20701 agcattggaa aggaaaatcc caactgttga cagtcacgat gtctaactcc gtgggcggtt
    20761 ttacaaattt tgacgactca gcgaccctag atgatggaaa atttcatgta acgatcgtac
    20821 cttccttaga tattttccga tttatttttt atttgcctag aatcatgaga ggcaaattct
    20881 atacgatccc cggcattact tatttcacag ccaaacgcat gaaaatccaa gcgcaggaaa
    20941 aatctgtggg cactcgaacg gatggagaca cgacagatga tcttccagtt gaattatctg
    21001 ttgtatcaaa aggattaaca gtttattcac caaagaaaga agaaaaagct tagaaatagt
    21061 agttaacaga aagttggaag aagagtaatg gatgtattgt tacacaatct tttgtggttt
    21121 taccttttca ttgtgaattt ttacttattt tgtctgatgg ggtatgataa acatcaggct
    21181 agaactagcg gctggcgtgt tcctgagaat aatttgatat ttgtcagcct gttaggcggt
    21241 ggtttgggag gattgatctc tcgaaaagtt ttccatcata aaactcggaa aaagaagttt
    21301 actataggat tcgctgcagg tgtacttgtt gatttgattc tcatttattt tttccattaa
    21361 ggagcaggag atgtcgtcta aaggaacgaa aactaaaatc attctgaatc tgcttttgct
    21421 gattgtgatt tttgccatta tttattattt aatcaatcaa tcatttgcag atatctttgc
    21481 cgaattgctg tctaccagtg ttgttgtttt ggcagcggct gttatattag ggacagttta
    21541 ccaaatcgct gaagggcgct caatcaaaga aattgctgaa cctttcgcgc cgaattttac
    21601 aacgaaagat gggttcttga cctctagcta tattgcgttt taccgaatcg tttcgtttgg
    21661 tacaggaacg ctgatctcgg agatttattt ttataacaaa aaaggaatga agctatccca
    21721 gggagcaggg gtgacagcac tccatatgat tatgtacaaa ctggcagtga tcacttatgc
    21781 attagctggc ttggtcatcc aattctctct tttttattct aatggtccat caatgatctg
    21841 gtttatcatc gctggtatcc ttttgacgat cgtgattgtt gcctttttat tggcgatgtc
    21901 cgtcagcttg aatgttcaaa tattttttgt cagcttatcg aataagttat ttaaaagtga
    21961 gcgtttgcgg aaatgggtgg atacatgcaa tcagcagatc tactctttaa gggaaacggt
    22021 ccaaaccatt atccaagaca ggactgcgct attgcggatt tatctatgga atatgttaaa
    22081 acttgtattt tggtatgtac ttccttattt gattctgatt gaaaaccatc ctaaaataga
    22141 ttttctactg accatttcgt ttatcagctt tgcagtagtg ctttcagggg ttattcctac
    22201 gcctgctggt attggttcct ttgaatttgt ctatttgtta ttattcagac cagttgttgg
    22261 aacagttgac gcagtttctt cgcttttact gtatcgtttc agttccttta tcttgccatt
    22321 tctctatgga tttgtgtatg tgattgctga acggcgaaga gtgatcaaag aagaaataat
    22381 agaagtaaaa aaagagaata aagaaaatca agggtaggtc ttttataaga tctacccttt
    22441 ttatcaaatc aaagaaaaac gttatggata agataatttt acgtttgttt ggctcttttt
    22501 ttatatacat acaatcaatt ttgttttttt aagatttata taagtcgaga aaaaaagtca
    22561 aaaaaccatg tgtatatttt gaccaaaatt gaccaaagcg atataatagt ttttgtaaag
    22621 atcaaagaaa taagtgatct tacctttaat taggagggta tacctgtatg aatattgaga
    22681 aaatgactac gacgcttcaa gaagcgattg ctgaagctca acagattgcg gtcactcgaa
    22741 aacatcaaga tatcgacatt gcccatgtat ggaaaatctt tttacaacct aatcattttg
    22801 gtcgaaattt ctatacggat gccggattgg atgtcgaatc ttttgaacat gaaattgatc
    22861 gtctactgga tgagtatcca gttgtttctg gtggaaacgt ccaatatgga caaaacctca
    22921 gccagaattt ctttcgatta ttgaatgaag cagaccaaat acgtgaaagc ttcggcgacg
    22981 agtttctttc aacggaagtc gttattttag cgttgatgaa attaaaaaat tatccgttaa
    23041 ctgtttattt gaataaaaac ggattatctg aaaaagaatt gcgtaaaaac atcgaagaga
    23101 tgagaggagg agaaagagtg acctcacaaa accaagaaga acaatacaaa gcattagaaa
    23161 aatacggcgt tgatttagta cagcaagtca aaagcggaaa aatggatcca atcatcggtc
    23221 gtgatgaaga aatccgtgat gtcatccgta ttctttcacg aaaaacaaaa aataatcctg
    23281 ttctgatagg agaacccggt gtagggaaaa cggcaatcgt tgaagggctt gctcaacgta
    23341 tcgtacgcaa agatgtgcct gaaaatttaa aagataaaac gattttttca ttagatatgg
    23401 gtgcattgat cgctggagca aaattccgtg gtgaatttga agaaagacta aaagcagtct
    23461 tgaaagaagt caaaaaaagt gatggacgta tcctcttgtt catcgatgaa atccacaata
    23521 tcgtaggggc aggaaaaaca gaaggaagta tggatgccgg aaatctgttg aaaccaatgc
    23581 ttgctcgcgg tgaattacat ttgatcggtg ccacaacttt agatgagtac cgtcaatata
    23641 tggaaaaaga caaagcgttg gaacgtcgct ttcaaaaggt attagtcaaa gaaccaacag
    23701 tggaagatac gatcagtatt ctgcgtggat taaaagaacg ttttgagatc caccatggtg
    23761 ttaacatcca tgacaacgca ttagtagcag cagctacttt atctgaccgt tatattactg
    23821 atcggttctt accggacaaa gcaatcgatt tgatcgatga agccagtgca acgattcggg
    23881 tagaaatgaa ctctatgcca acggaattag atcaagttac tagacgtttg atgcagttgg
    23941 aaatcgaaga agctgcactg aaaaaagaat cagatgatgc aagtaaaaaa cgcttgaaaa
    24001 atttgcaaga agaattagct gaacttcgtg aagaagcaaa tgcgatgaag atgcagtggg
    24061 aaacagaaaa agaagaagtc aattctgttt cagcaaaacg tgctgaaatc gataaagcaa
    24121 aacacgaatt agaagatgca gaaaataact atgatttaga acgcgctgct gtattgcgtc
    24181 atggtacgat acctcaatta gaaaaagaat tgaaggaatt agaagctaaa gcaaaagaca
    24241 gcgagattaa gatggttcaa gagtccgtta ccgaaaatga gattgctcaa gtcgttggca
    24301 gattaacggg tatccccgta acgaaacttg tagaaggtga acgagaaaaa ctaattaaat
    24361 tgaatgaaac acttcataaa cgagtgattg gtcaagatga agcagttgat gcggtcagtg
    24421 acgcggtaat tcgttcacgg gctggattgc aagacccaaa tcgtcctcta ggttctttcc
    24481 ttttcctagg accaactggt gtcggaaaaa ccgaattagc gaaagcgtta gctgagaact
    24541 tgtttgactc agaagatcat atggtacgga tcgatatgag tgaatatatg gaaaaacatg
    24601 ctgtgtctcg tctagtcgga gctcctccag gctatgtagg ttacgaagaa ggtggtcaat
    24661 taacggaagc tgtcagacga aatccttata caatcgtctt gttggatgaa atcgaaaaag
    24721 cgcatcccga tgtcttcaat atcttgttac aagtcctaga tgacggacgc ttgactgatt
    24781 caaaagggcg agtagtagat ttcaaaaata cggttctgat catgaccagc aatatcggtt
    24841 cacagttact gctggaaggc gtgactgctg atggaacgat tccagaagca gtggctgaac
    24901 aagtcaacac gctattacgt ggaaacttca aaccagaatt cttgaaccga atcgacgaca
    24961 cgattttatt tacaccattg agcctagaca acgtgaaagg aatcgttgac aaaatggtgg
    25021 cgcaattggc acaacgtctg gaacatcaag aaatcctgct gacaatcagt gatgaagcca
    25081 aaacgtggat tgctgaaaat gcttatgaac cagcatatgg tgcaagacca ttgaaacgat
    25141 ttatcactaa ggaagtagaa acaccactag ctaaagaaat cgttgcagga catgttatgc
    25201 ctaaatcaaa agtaacgatt actttacttg atggacaact tcatttcaaa acagaagagc
    25261 tagaagaaat cgtctaatct tccattgaga ctataaaaga aaaaaggggt ctgacacaac
    25321 tagtgtcaga cctccttttt tcaaataaac agtgttccag aagtagtttc ttcgaaaaat
    25381 aagccgaaat ttcttgaagc tgcccgcttc tgtcacaacc tcttttatta ggtatttttc
    25441 actttttcta atttataact ttcaaagtaa cgctcatctt ttttactttg agaccatgca
    25501 aacaatccca ttaaggcagc acctatcgta tttgtcagca agtcgcccat cgtatccatc
    25561 aatgctgctc gtccgacaaa cagtgtgcca tcagaagcag caaaacgttg aagattcatg
    25621 cctaagaact ggtcgcataa gaattcccag aactcccaaa acacgccgca aagtccagca
    25681 aacgcaaagc cgaataagag gaacaaccaa ggactggttt ttgatatctc agcatctttc
    25741 atcaagtaac caatcaatcc atagccaaga gctgtcagga ccattggact caccgcatgt
    25801 aagattttgt cccaaaaaga gatgatactg atcaaatgca tccctgtgcc taaaaagaca
    25861 gagatgaaca agaaaaacca gtaaaacaaa acgattgctg ctggtatttt aagtttgaaa
    25921 actttcaaaa tgacttgtgg catgaaaatc aatgcaatcc ctaataaaga ttccacgata
    25981 aatgtgattc cttgagaagt cgaatatttt tgtgtgataa attcataaaa attatagcag
    26041 acaacgaata caccaaaagc aagtaaagct atttgcacct ttttgatttc tttaatcact
    26101 gaaagtccct ccatctaaaa atctttttac ttctgaaagc aactcaattt ctgaagaaac
    26161 cacttttccg ttcaatttga tcaaacctat tgtatataag ttcaggtagt gaaattgatt
    26221 ttcagctgtt tcttgtagtg cagcgatttt tttcgggtgg gttccgcctt gctgtcgagt
    26281 atcagtatat aagccgatca ctgggatgcc tttcgcataa gccacaccga tttccgatgc
    26341 taccccggca tcgatcgtca gcccatctag taaagcaatc attaaatcac tagccaacac
    26401 tttttctgtg tcagcaagag caatcattcg actgtctgca taagcagttt tgtcattgat
    26461 tgcttcattt tcttgaggaa gatagatcga aagctcagaa gagagctctc tgatttcttt
    26521 aactaactgt tggttatata acaaatcact tttagcaaac attggtgcgg caaaataaat
    26581 tttcatctaa acatcatcct ttttatcaaa aataatcgct aaagtaagct tccatgtttg
    26641 gaatgatacg ctctagtgac ttcagtgttt cttcatctgt ttctaaccgt tcgattcttg
    26701 ccaaataaga agcacggcga taattcatca tcaagcaagt caatgtttgg atatccagtc
    26761 gaacggattt tcctataggt tcatttaaga cacggacttg tccctgttca tcccatgtta
    26821 aagcgaagac accattattc caaggagcga caggatcttc aatgatgaaa tgaaaagcat
    26881 cagctgttcc aacaaacgga aaccgttgaa ggaattcttt tacatcaacg atccgagcca
    26941 taaaatatgg ttcgatctgc tctttgatct gactatcttc aatcaaaaat gctaaaggct
    27001 catttttata aatatctcca tgtacccagt agatcatgga aaaatgtgcg gaaataaagt
    27061 tccataagcc atttcgagct tcttgatcaa gatagaacat ttcttttacg tgaaatattt
    27121 cttcagctac ccagtagaac agaacacctc ttggttcatg gttgctatcg tagtagacag
    27181 cggctgtgcg ctcatcttca ttttcgaaac gccaatactc ttcccaatga aaatcactgc
    27241 ggaataaagc accatggttt tgttgggcaa atttgtcata aacggaaaat acgtctggat
    27301 gatcaactgg taatcgctca accataccac ttactgggat ttgtttaggt agctgtgtat
    27361 ctctgatttt aaaggaaagt ttatcagaca tgatttccca tcctttacgc cgatagtagg
    27421 ggatactgta aggatacaaa taagagatcc attgcttatt cttgcgcata ttatccaatg
    27481 caacgataat tagatcttgc atcaatccat ggttagcata ttctggataa gttccaactc
    27541 cagtcacacc acccatttta taacgtgcac cgtgaatatt gacttcacaa ggatagatag
    27601 cgatttgaga gatcagttta ttttcgtgga accatccgaa cactttcgat acttccaaaa
    27661 tcggtttttt ggaacggata aaagctcgtt tattctcaaa cccgctttcc tcgatgtctg
    27721 cttcagtcac ttggaacaca taggaaagca attcattgaa ttgatcgata tgttcttgag
    27781 tgaccggttt taattcaaga ttttctctaa aatctttttg atccattttt tcatctccat
    27841 ttattagctt gataacagta tagcaaaatt ctacaaaaaa aacttctata gctgactaat
    27901 taaaaactct ttaaattact gcttttcgtt ggtataatgg aaagtgctga ttatatgaaa
    27961 agaggagacg ctatggatat aaagaaaatg aaagaacgcc aagagcagat tcgtaatttt
    28021 tcgatcatcg ctcatatcga ccatgggaaa tctacattgg ccgatcgtat tttagaaatg
    28081 acgcacactg tgacgtctcg cgaaatgcaa gatcagctgt tagactcgat ggatttggaa
    28141 cgtgaacgtg gaatcacgat taaattaaat gctgtagaac tcaattacac agcgaaaaat
    28201 ggagaaacat atatctttca cttgattgac accccagggc acgtcgactt cacctatgaa
    28261 gtctctcgaa gccttgctgc ctgtgagggt gccgttttag tggtcgatgc agcacaagga
    28321 atcgaagcac aaacattggc caatgtttat ttagcgttag acaatgattt ggagatcctg
    28381 ccagtcatca ataaaatcga cctacccgca gcagatcccg aacgtgtccg tcaagaaatc
    28441 gaagacgtaa tcggaatcga tgctagtgaa gctgtattag ccagtgccaa atcagggatt
    28501 gggattgaag atattctcga gcagatcgtg gaatatgttc ctgcaccaag tggagactta
    28561 gatgcaccgc taaaagcttt gatctttgac tctatttatg atagttaccg cggtgttgtt
    28621 ctaaatgtcc ggatcacgga cggtatggtc aaacccggag acaaaatcaa actgatgagt
    28681 aatggcaaaa catttgatgt tacagaggtc ggggtcttct cgccaaaagc agttgctaga
    28741 gactttttga tggtcggtga tgtcggttat atcacagcaa gtatcaaaac tgtccaagat
    28801 acacgagtag gggatacagt aacgttagca gacaatcctg ccgctgaagc tttaccaggt
    28861 taccgaaaaa tgaatccgat ggtttattgt ggtctttatc caattgatac ttctcgttac
    28921 aacgatttgc gggaagcttt agaaaaactg caattgaatg atgctgcttt acaattcgaa
    28981 ccagaaacct ctcaagcatt aggttttggg ttccgctgtg gattcctcgg acttcttcat
    29041 atggatgtcg tccaagaacg cttggaacgg gaattcaatc tagaattgat cacgactgca
    29101 ccatccgtta tttaccatgt taataaaacg gatggtacga ctgctacagt agataacccg
    29161 gcagattttc ctgaacctgt aacgattcag gatgtagaag aaccattcgt caaagcacag
    29221 atcatggtcc caaatgattt tgtcggtgca gtaatggaac tttctcaacg aaaacgggga
    29281 gaattcatta cgatggatta tttagatgat taccgagtaa atgtcgtcta taatattccg
    29341 ctttctgaaa ttgtctttga ctttttcgac aaattgaaat caagcacgaa aggctatgcc
    29401 tcattggatt atgaaatgtc tggttatcaa aaaagcaagt tagtgaagat ggacatcttg
    29461 ctgaatggag aaaaagtcga tgcattaagc tttatcgttc accgagactt tgcctatgaa
    29521 cgtggaaaag caatcgttga aaaactgaaa aaactaatcc cacgccaaca atttgaggtg
    29581 ccaatccaag cagctattgg acaaaaaatc gttgcccgtt cagacatcaa agccttgcgt
    29641 aaaaacgtct tggctaaatg ttatggtgga gatgtttctc gtaaacgtaa actcttagag
    29701 aaacaaaaag aagggaagaa gcggatgaaa caaatcggct ccgtcgaagt tccgcaagaa
    29761 gccttcatgg ccgttctgaa aatggacgag gacgaaccga agaaatagca agggtttgtt
    29821 tgaaaacagt gtaaaaaata aaccatgttt acatggattt gccaccggtt tgccaccggt
    29881 ggtttttttc ggtggcaaaa atcaagaatt ctttctaaga ttttccatga tatcgaccgt
    29941 ttcatttctc atcttatctg ttacatgcga gtaagtatcc atcgtaattg aaattctgct
    30001 gtggcccaat cgttcagaga tttctttcat ttttgcgcca ttttcgagaa gaagtgtagc
    30061 atgagtatgt ctgagagaat ggaagttaaa agagagggag agtgcattcg atatcctcct
    30121 agtattccat ttcactacac ttggcgtaac tagctcaccg tcttccttcg tacatactgc
    30181 atttgaatca atgtagagct ttccatactt cattcgattt tctaattgtt gtttcttatg
    30241 ttttttcaga attgctagca aggtttgtcc aataaaaatc gttcgattgg aactgcttgt
    30301 ctttggcgta ccatataccc atgcgccgtc attctttacc atttgtttct ctacagtaat
    30361 tgttccattt gaaaaatcga catcatccca cgtcagacca caaacttcgc caacgcgcat
    30421 tcccgtataa aatccaatat tcaaaggaat atagaaagga tgtccttcag gagtaatttc
    30481 tagcatatga tcaaagtcct caagagaaat gatttttaga tcttttttag tcgttggtcg
    30541 tgcttcatat tttggtattt ttacatacag cataggattt tgcttgatta atccccaagg
    30601 ataaaccgcc atattcagcg cattcttaag gacagagtga gtaatagtca ttgttttctt
    30661 cgagtaaccc tttttaaatt cagcattgat gaaattttgt aaaagaacag gggagagatc
    30721 cgtaagtttt ttctttccta aataaccgtt tatatgattt ttgatggtaa atcggtagtt
    30781 ttcataggta ttgtatttta gatttagttt aacgtattcc tccatccaaa aatcaaggta
    30841 ttgttttact cgagtatccg tacctaaaaa gtattgtcct gtttcgtcaa tatctgataa
    30901 aacttttcgt aaagcagctt cggcctctgg tcgggtgtct ccgccaactt tctccacttt
    30961 ttttcttgag ccatcatcat tgatatcttc gccgtttgta taattaagcg agacaaa
//
LOCUS       DAFEEZ010000031        31011 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000031
VERSION     DAFEEZ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31011
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.031"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="LP245_001477"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="LP245_001477"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBL1519402.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
     gene            1710..2027
                     /locus_tag="LP245_001478"
     CDS             1710..2027
                     /locus_tag="LP245_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBL1519403.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNASIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(2231..2596)
                     /locus_tag="LP245_001479"
     CDS             complement(2231..2596)
                     /locus_tag="LP245_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519404.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            2804..3286
                     /locus_tag="LP245_001480"
     CDS             2804..3286
                     /locus_tag="LP245_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519405.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            3483..4373
                     /locus_tag="LP245_001481"
     CDS             3483..4373
                     /locus_tag="LP245_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBL1519406.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            4698..7169
                     /locus_tag="LP245_001482"
     CDS             4698..7169
                     /locus_tag="LP245_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL1519407.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(7272..9008)
                     /locus_tag="LP245_001483"
     CDS             complement(7272..9008)
                     /locus_tag="LP245_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBL1519408.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(9005..9709)
                     /locus_tag="LP245_001484"
     CDS             complement(9005..9709)
                     /locus_tag="LP245_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1519409.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            9840..10343
                     /locus_tag="LP245_001485"
     CDS             9840..10343
                     /locus_tag="LP245_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBL1519410.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            10303..10641
                     /locus_tag="LP245_001486"
     CDS             10303..10641
                     /locus_tag="LP245_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBL1519411.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            10662..12080
                     /gene="ffh"
                     /locus_tag="LP245_001487"
     CDS             10662..12080
                     /gene="ffh"
                     /locus_tag="LP245_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBL1519412.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            12192..12770
                     /locus_tag="LP245_001488"
     CDS             12192..12770
                     /locus_tag="LP245_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBL1519413.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            12774..13295
                     /locus_tag="LP245_001489"
     CDS             12774..13295
                     /locus_tag="LP245_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1519414.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(13374..13928)
                     /locus_tag="LP245_001490"
     CDS             complement(13374..13928)
                     /locus_tag="LP245_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBL1519415.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            14181..14456
                     /gene="rpsP"
                     /locus_tag="LP245_001491"
     CDS             14181..14456
                     /gene="rpsP"
                     /locus_tag="LP245_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBL1519416.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            14468..14719
                     /locus_tag="LP245_001492"
     CDS             14468..14719
                     /locus_tag="LP245_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBL1519417.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            14844..15635
                     /locus_tag="LP245_001493"
     CDS             14844..15635
                     /locus_tag="LP245_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519418.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            15805..16326
                     /gene="rimM"
                     /locus_tag="LP245_001494"
     CDS             15805..16326
                     /gene="rimM"
                     /locus_tag="LP245_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBL1519419.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            16316..17077
                     /gene="trmD"
                     /locus_tag="LP245_001495"
     CDS             16316..17077
                     /gene="trmD"
                     /locus_tag="LP245_001495"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBL1519420.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            17213..17560
                     /gene="rplS"
                     /locus_tag="LP245_001496"
     CDS             17213..17560
                     /gene="rplS"
                     /locus_tag="LP245_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBL1519421.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(17692..18828)
                     /locus_tag="LP245_001497"
     CDS             complement(17692..18828)
                     /locus_tag="LP245_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1519422.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLHKPDLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKIPETYIVSGINTIDLNNIFEDMIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKN
                     PIDEVVIDYKRESKTIKIKDKFLEDDEYNRLVDFTTSHNKRYSLLFQWLYLTGMRSGE
                     AIALSKDDVHITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAI
                     YNELLELNPNGQFLFQTTKGTPFQLTAINTYLRSHKADMKIDKKLSSHIFRHTHISKL
                     AELGTPLYAIQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
     gene            complement(18944..19510)
                     /locus_tag="LP245_001498"
     CDS             complement(18944..19510)
                     /locus_tag="LP245_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HBL1519423.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWLLAVVVVFIAIGSQGGSD
                     DAKNTVAETTKESVTEVSSAESVAESTVVEEETETTETTIEEVTQEESVPREYRNALS
                     KAESYLGWAGMSEQGLREQLEFEEYPSDAIDYALANVDVDYNEQALAKAESYDDWASM
                     SDSQLYDQLIFEGFTNEQAQYALDNLPQ"
     gene            complement(19646..20299)
                     /locus_tag="LP245_001499"
     CDS             complement(19646..20299)
                     /locus_tag="LP245_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519424.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDTTSNQETKISKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQATAEPSPTVISSSQSTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     AQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFSKYGIQ"
     gene            complement(20349..20777)
                     /locus_tag="LP245_001500"
     CDS             complement(20349..20777)
                     /locus_tag="LP245_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL1519425.1"
                     /translation="MEMDTINLVEELKRKYQSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRDRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKKIEELKNLYGLPESAYRFLI"
     gene            complement(20782..21156)
                     /locus_tag="LP245_001501"
     CDS             complement(20782..21156)
                     /locus_tag="LP245_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1519426.1"
                     /translation="MSLVTKIKELADEKHVTIAEVERQVGISNGQIRRWDKASPKSEN
                     LKKVADYFGVTTDYLLGNNNVPKWATKEEVVELDKLLDSNVNMSYGGETLTPEQIQRV
                     KDILIATFWDIVKEDKEKGKKM"
     gene            21460..21645
                     /locus_tag="LP245_001502"
     CDS             21460..21645
                     /locus_tag="LP245_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1519427.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALIGISGAYLSDILNGNRDG
                     KKAQQHIETVKKILDIR"
     gene            21658..21906
                     /locus_tag="LP245_001503"
     CDS             21658..21906
                     /locus_tag="LP245_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519428.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKVTPKEFIEKHLVDL"
     gene            21937..22107
                     /locus_tag="LP245_001504"
     CDS             21937..22107
                     /locus_tag="LP245_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519429.1"
                     /translation="MGKFNRALVFSAPLIVYALGLWGSRQALIGTIVYMVWIFIGLDE
                     AEYKTKKPVGRD"
     gene            complement(22209..22667)
                     /locus_tag="LP245_001505"
     CDS             complement(22209..22667)
                     /locus_tag="LP245_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519430.1"
                     /translation="MIKILSDYQVAITLIISISGFFLSLYNLFKDKRKITLSYFLVKH
                     DRSNRMILTGVIANPSKMPNSIIECTYLYNGKKINCSHYHANGFDMGSIHKSSLLSPI
                     PLAQAISPGYSVAFSEVLDMKDILPGEKLVMVIRTANYQKKFKLKLKDSF"
     gene            22835..23152
                     /locus_tag="LP245_001506"
     CDS             22835..23152
                     /locus_tag="LP245_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519431.1"
                     /translation="MLIATDTLDRIFLKDEYKLRNIDASGILVFDLYDNGKIGIYQAS
                     DIEETNLAFEQIDDSVELDLDEAILAFEQIAKLLKEAQKNGNSLPTQRVIYQSPGTGR
                     TIG"
     gene            23085..23564
                     /locus_tag="LP245_001507"
     CDS             23085..23564
                     /locus_tag="LP245_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HBL1519432.1"
                     /translation="MATLYQLSESYIKVLELAEQLDEEILRDTLDSINEAIEYKAENL
                     AKIVKEVEGKAELIDSEIKRLQERKTSLLNNAKSIKHYLQEEMEKTGKTKIKGELFNI
                     GIQNNPVSVNVINENLIPKGFFTPVPPKLDKKQLKEELKHGDIPGAELVQTKGLRIR"
     gene            23581..23757
                     /locus_tag="LP245_001508"
     CDS             23581..23757
                     /locus_tag="LP245_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519433.1"
                     /translation="MEHENVKDALKAAIEIAEAKGIKVDGKPATVHDIQNLTKEHLYF
                     IADLLGLSELYLDK"
     gene            24014..24445
                     /locus_tag="LP245_001509"
     CDS             24014..24445
                     /locus_tag="LP245_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519434.1"
                     /translation="MKNKLAKTTAIIGLALGSGVIGYAASNAFQDLDTIKANFNTVLQ
                     YGQTKSQRVSELESQLSNNTRTQEQLKAEIEQIKSDKQKEIEAKQREIEQKQQEIATK
                     QQEADSLRQQLSTVQNDKEQLEQRVSELRQYTDQKVGELGK"
     gene            24451..24768
                     /locus_tag="LP245_001510"
     CDS             24451..24768
                     /locus_tag="LP245_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HBL1519435.1"
                     /translation="MTIYDPNISWAKHTIKVSFMIWGYKGYVTYKVGGNTKGLSLIAI
                     DSDDLYDANFEDNPVNFRDLDEDWFSMELTNDKGDSTLVEDEFDRLGDYIVGVEIIAH
                     EPE"
     gene            24887..25573
                     /locus_tag="LP245_001511"
     CDS             24887..25573
                     /locus_tag="LP245_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1519436.1"
                     /translation="MQIKKATDIEQTKGTYLIYGAPGKGKTSTAKYFPGKTLILDIDR
                     TSKVLRGEKNVDIVYIDNEDTWNDWGNTLADLTTNYVGVYDNVVVDNVSELERCILSS
                     LGAEGKNNGVPSQGDYQYMQFRMVNSLRYMKNLDSNLIWTAWEEIDLWTDSDGSSYNI
                     ALPQINRKIRNNILGLCDVVGRLMVKEDDERGFILQATDSTYAKNQLDNRSGCKQSEL
                     ILYGIVRLPE"
     gene            25548..26897
                     /locus_tag="LP245_001512"
     CDS             25548..26897
                     /locus_tag="LP245_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL1519437.1"
                     /translation="MELYDYQNDLVDRARQAYVDGYKAPCIVSPCGSGKSVMVAEIAK
                     RTTRKGNRVLFLVHRRELIDQIKDTFQKMGVDNQLVNFGMVQTVVRHLKTIKKPQLII
                     TDENHHGLAASYRKIYEYYSDVPRLGFTATPIRLNGSGLGDVNDLLIEGVSAKWLIEN
                     HRLAPYEYYAPKLIDTAELKKASTGDFTKKSMDKAVKNTIYGDVLKHYKTLAEGEQAI
                     AYCHSIDASKHTAEIFNDAGYKATHIDAKTPKDERADIIEAFRNHEIKILCNVDLIGE
                     GFDVPDCSTVIMLRPTQSLSLYIQQSMRGMRYRPDKTSIIIDHVGNVNRFGLPDMDRE
                     WSLDTKKKTKTDSDLSIVQCAFCFGAYERPKGDNICPYCGELQPIEERKSELEIDESA
                     ELMKVGETKITLNFENNKYYNMTEDEAESIEDLYAIARAKGFKPGWAYMAAKRKGWL"
     gene            26888..27361
                     /locus_tag="LP245_001513"
     CDS             26888..27361
                     /locus_tag="LP245_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL1519438.1"
                     /translation="MVVGMGGIFGKKAEDVQGSIINGVTIIGDTGKRDSSGNQIVIAR
                     NKNNEVFESSLSNIKRGVVNGTGEESGYVNLKKANEKYHVEGTYVKALSVGGTKGVNW
                     DKRRNKWKARLYFKGEYVLQKDFNTKEEAIQARLAAEEKYFKPILEKYENKKEND"
     gene            27336..27863
                     /locus_tag="LP245_001514"
     CDS             27336..27863
                     /locus_tag="LP245_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF669 domain-containing protein"
                     /protein_id="HBL1519439.1"
                     /translation="MKIKRRMINMTGFNLDFSKAQQGNEIKDGTYEVVVNKAVENATK
                     SGAEFIDIDLIVRNDVDQPFQNKHIFAKIWKAKATGKYNEGMIMAIAQALQLEDGKSY
                     NGFDELLADFVLKTASVRVKTEESNGYKNVNVKSWDKTNTRGVMNHQFKNGDEPSFGP
                     ERSRATTVRNDNLPF"
     gene            27878..30190
                     /locus_tag="LP245_001515"
     CDS             27878..30190
                     /locus_tag="LP245_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBL1519440.1"
                     /translation="MYEKIPKELKNLKQWCVYKLVWDEKRQKHTKIPYNANNGHKAKS
                     NDESTWSDFQTALAAIDHYGMSGLGFFFKPPYFGIDIDNAEGEVERFKSGDIEENIIY
                     EFIESMRSYAEYSQSGTGIHIIARGELPGGRRRKGDVEMYQNGRFFVMTGNAASKYLE
                     ITEPNPKDIKRLYDRYVGDEKIIQFKEENPLMNTVDLPVEEIIKRAESSSQGARFKVF
                     MNGGWEAFYSSQSEADMAFANDLAFWTGRDFEKMDEIFRASAMIRSKYDQKRGSATYG
                     ESLLNKAIADTNSVYNPKRKSDFKIFIKDQEQPKEEKYYSYDDTGNADRFTDIYGTLV
                     KYSYIDKSWYYYDGKVWLQDNTGEVRKMIDTTVDIMGKEPLTIPEGADDETKEALMKA
                     KEKHVKRSRSNAGKNAMMDELKHRLSVLPEEFDKDKTLFNTQSGYLSLHDGLLHEHEI
                     DKMFTRVSNVEYTESVDCPMWEEFINQIFDNDQELIRYIQKCVGYSLTGSTGEQCMFI
                     LYGHGSNGKSVFLEIISELMGNYAMTMQAQTIMVKQSQSSANSDIARLKGARLVTSSE
                     PNEGVRLDEGLVKQLTGGDKVTARHLYGKEFEFEPEFKLWLATNHKPIIRGTDDGIWR
                     RLNLIPFTVQIPDHKKDKNLKFKLQTELQGILKWAIDGCLLWQREGLEKPKSVVAASQ
                     DYRNEMDQIGTFIETCCETGPGLKISGGELYKVYREWASDNGEHTFTNTKFGREISKK
                     YSKEKAGGFMVYKGITLKPRKYDNVRELFK"
     gene            30437..30754
                     /locus_tag="LP245_001516"
     CDS             30437..30754
                     /locus_tag="LP245_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HBL1519441.1"
                     /translation="MKSEHQIQDEIRIALSKHGCTIFRSNAGQVTTIEGRQFYGMPKG
                     FPDLCGHRNSDGKAIYIEVKNERGKLREDQKRFAEFLNGQPVLYGVARSVEEALKIVE
                     ESS"
     gene            30751..30912
                     /locus_tag="LP245_001517"
     CDS             30751..30912
                     /locus_tag="LP245_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBL1519442.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDVHIENL
                     RREIRRLEE"
BASE COUNT        10373 a         5317 c         6258 g         9063 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtca ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta acttattgct tttgcaaaat ttatttacct gttttctgga tcaacgatag
     1141 tgtatattat gctatccttg tttggatttt aggacgttta aagaggcact tttttacata
     1201 acttaatcca tagacctttt aagcatgctg tgagataata ataaagaaga gtttaaagcg
     1261 caccccaaac cacttcccca taagtgtatt acgctttaaa ctcttttata tttgaattca
     1321 ctaagaagca taccatattt ttgaaaaaaa gtgagaaaaa aggcttataa ttaggattta
     1381 gagtaattaa ttagatgttt attttatagg actgatatta tagattacaa atagtatcgt
     1441 atttcgcaat cttaaaatta tcttcttact atgaataaga taataaaatt tgtatttgtc
     1501 ctttttaggt aacttatttt aatctatata cctttctgga tcaacgaaag tatactttat
     1561 atagtcataa cgccgatggt aactatgcac tgtaacgata atgctgctaa aatatctttt
     1621 tacgaaaaac atcacaagga aaaacttaac tatggtatta tctaaacata attttttcgg
     1681 tatttaatat ttaattagga gggaatattt tgctttttta tagtaatttt atcttaatag
     1741 tagcgatatt attacttctg aatatatgga tttttgatag gagtagaaat gcaagtatag
     1801 gttttagaac taaacgaagt ctgtcttcta aaaaaaattg ggtatactca caaactattt
     1861 tttatggagg aattgtttta attagtttac tttcttcaac actttattct ttgaatatta
     1921 tagatgtttc cacctcaaat tcaatatcta ttattggaat cattattgct gcaattatta
     1981 cacaactgtt tttagtgttt ggagagaaga aaagaagtaa aaaatagaaa aactagtgat
     2041 agttttggtg atagtgatat taaaaatcag aaaagataga aaaagcagga gatagataaa
     2101 atgctgatat ttcagcattt tttaagagta taaaagagaa aaaaagtaat aaatgtatac
     2161 atgatataag aaaaacatat atgtataaaa agaagaaagt agcttctctt tgtacatata
     2221 tggtttgttt ttatggatgc cgagcttttt tataagataa ggctaccgcc cataacgacc
     2281 caaggatttg tggaactaag taaatacctg caagaagcaa gatcagctgg gtcggtttta
     2341 aaggatgata gaagtaacgc cattcagtaa aattggcgca aaataaatag gaagtgacag
     2401 tagatataat attggcaatg aataaagata taatacgcct gttcctttga aaataatatc
     2461 cagcaaaaag agataaaaat atcaatgtga tgaacccgct tacggaatga taacgaaaat
     2521 caagcagtaa ggcgaaatgc acataaggaa caaaagataa aagcaacgga aggtttttcc
     2581 agcaagtttt tatcatcttt catcaccacc taacaagtgt tattattttg ttagttttat
     2641 tgtaaattga atcctgcaat aatcaattac tttttcatta tttctagatt aaatgaataa
     2701 actctcatgc cattatctct aaaaaaaaag tttttccccc taattttttt agatagaaaa
     2761 ttgtatagta tgatgagaga aaaagtagtt tgggggaacg ttaatgagaa gaaaagcagt
     2821 aatcgatcgg ctttatttat ttttttggtt ttttcctatc gttttgctac cttttacatg
     2881 ggtaaatgct gttgtacaag gtgcggagat attaggcctg atccaaggaa gcggatttgt
     2941 ggtttctagg aattttccag ctttgactgt tttctattta gtgataagtg taggtctctt
     3001 attaccaaaa tctctgatca atcactacaa ttggcagctg ctttactttt cttgcttatt
     3061 agtatttaca tctatgtttt ctttgctgcc tcgcttgatt atcggcccta atggtttgag
     3121 cgagagtgga ttgaaggatt cagcttattc ctccatgtat ttcttgacga tcaaaccatg
     3181 gttctattta gtaattgcct catttattct tgcaacattt ttttacttct ggacagaaat
     3241 caggataaaa agtgaacgat ctgtatctat aaaaaataac tattgatggt ggatcatcag
     3301 taaaaaagca tatgagctgc gtaaaatgca tgtttctcat atgctttttt tattattatg
     3361 taaagaatgc gaaaaacgtt tacatgattt ttacataact taactatatt tttacagcaa
     3421 ccatacgagg gatttacagt cgactgataa actttagttg taaataagaa aggagcaata
     3481 aaatgaaaaa agtattgttt actctaggta tgatgggaat tcttttagcc ggatgcggct
     3541 caggatcagg aaatacagat ggctctgcca cacaaaataa ttcaagtgac tcaaatgaac
     3601 aagtaaaaat cgttgcggta ggttcgacag cattacagcc gttagtcgat gcagcacaag
     3661 aaagctttgt acaagaaaat ccaaattatc aaatctctgt acaaggagga ggaagcggaa
     3721 ctggtttgag ccaagtcgaa gctggagcag ttactatcgg aaactctgat gtatttgcag
     3781 aagaaagaga cggagttgat gcttcaaaat tagtggatca taaagtagca gtggtcggga
     3841 tggcgccaat cgtcaataaa gatacagatg tcaaagatat caccaaacag gaattgattg
     3901 atatctttac aggaaaaatc actaactgga aggaagttgg cgggaaagat caaaaaatca
     3961 acgtcgtgaa ccgtgcaaac ggcagcggta cccgcgcgac attcgaaaaa tggggactgg
     4021 atggtgctac ccctgtgcag tcccaagaac aagattcatc aggaacagtt cggcagctgg
     4081 taagtcaaac accaggagca atcagctatt tagctttctc atatctcgat gattccacac
     4141 aagcactaag tatcgacggt gtagaaccaa aagaagagaa tgtagcagat aacagctggg
     4201 gaatctggtc atatgaacat atgtacacga acggaaaacc ttcccctgaa gtccaaaaat
     4261 tcttagacta catgatgaca gaagaaatcc aagaaggacc tgtcaaagaa ttgggctatt
     4321 taccaatcac aatgatggaa gtagaacgtg atcacgaagg aaatatcaaa taactagcag
     4381 ataaacatgc cacggtagtc gttactatta aggaaaaatc aactatgttt cccacatata
     4441 catttttcct ttaattgtga aaaatagttc ctcatatttt gccgtttttt gagctaatac
     4501 cgagggtcag ctgattaaac accgtttatt cgaaaaaaag agctacgaca tagaactgtc
     4561 gtagctcttt ttttgctata tgacaggaat gaaaggtgtt tgcaagctta atgtgaggaa
     4621 cactttccat atctgttcta tactggatag gagaagtttg gaaatatcca gaaaacgaaa
     4681 tcaatcgagg tagccacatg aagaataaat ggataaatcg aagtaaaaaa aagaaagtaa
     4741 cacaaagatc atcagataaa gtcatccgtc tttttccatc gtataaagaa ggattaacgg
     4801 cagatcaagt caaggaacga atagaaaaag gtgcagcaaa taattcagtc gatcccacat
     4861 tcaaaacaaa tcagcaaatc gtattggaaa acatatttac gtatttcaat ttgatctttc
     4921 ttatcttagc cattttgctt tgtttagtag aatcctataa gaacttgact tttttaccag
     4981 ttatcatagc caatacagga atcgccattt ttcaggaaat tcgatccaaa aagatcttgg
     5041 acgaactaaa tgttttaaat acagcaaaag tcaatgtcat acgggacggg atagaacaaa
     5101 caatagatat agaagacctt gtaatagatg acattgttat tttagagact ggacatcaaa
     5161 ttccagcaga tgcagaggtc gtggaaggaa aactgcaagt taatgaggct ttattgacag
     5221 gcgaagcaga tgaaataacc aaagaaatag gcgatccatt aatgtccggc agtttcattg
     5281 tttccggaaa agcttacgcc cgattagaca aagttggagc agattcgtat atttcccagc
     5341 tgacagtcaa agccaagaca atgggagaag gagaacagtc ggagatgatt gcttctctta
     5401 atcaattgat caaatggatt gggatcatca ttattcctat cggtatcctg cttttttctc
     5461 aaagttactt ttttaatgga aacacgatca aagaaagtgt cgttgcaatg gaagcagcat
     5521 tgatcggtat gatacctgaa ggactgtact tgctgacgac gattgcatta gcattaagtg
     5581 cgactaaact agcaaagcaa agagttcttt tacacaatat gaaaagcatt gagacattgg
     5641 caagggtaaa tgtcctttgt gtagataaaa caggaacgat cacagaaaat aaaatgtctg
     5701 ttcaaaaagt gatcgtctct aaaaaacaag aaataatcag tcagtcagat caattggaag
     5761 catgcattgc tgactatgca aaagcgatgg caggagacaa tgcaacaatg gaagctgtta
     5821 aagcatattt tacaaaaacc actgatcaat cctatcacca tgttattcct ttttcttctg
     5881 tccaaaaatt cagcagtgta gcgttggcag acaaggtgta tgttttagga gcgcccgaaa
     5941 tggttttgcg cgatcaattg ccggaatatg cggaagagtt tgtttctttc gctgaaaaag
     6001 gctatcgcgt gttggtcttt ggtgtgtacg atgggattct tgaagaacca gtattgacag
     6061 aagcagtcac accattaggc tatattctga ttgctaatcc tatcagaaaa gaagcaagag
     6121 ccacatttga ttacttcaaa aaacagcaag tagccatcaa agtgatttct ggagataatc
     6181 cgctcaccgt atccaatgta gctgtccaag cagggatttc acatgctgat cagtacgttg
     6241 atgcatctaa attatcagaa gaagaatatg aagcagctgt cgaaaaatat acagtttttg
     6301 gacgcgtcaa gccagaacaa aagaaaatct tcgttcaatt gataaagcgt aacaatacag
     6361 tagctatgac aggtgatggc gtgaatgata ttctagccat gaaagaagca gactgcagta
     6421 tagcgatggc ttccggaaat gaagccgcca tgcaggcctc acaagtggtc ttacttgatt
     6481 ctgacttttc acgcatgcca gaagttgttg cagaaggacg gcgcgttgtg aacaatattg
     6541 agcgatcagc cagcttgttt ttagtgaaga atattttctc ctttttgctc tcactgtttt
     6601 cagtgatctt tgctctgacc tatcctttag aaccatcaca aatcacattg attagtttgt
     6661 ttactatcgg acttccatct ttcttgcttg ctctagaaga aaacaaaaag cgaatcagag
     6721 ggaaattcat catgaatgtg atggaaaaag ctgtgccagg tggactaaca gatatgatcg
     6781 tagtcggtgc gttggtgatc tgcggggtga ctttgaatct aaataaaaca gatgtttcta
     6841 cagcatctac catgcttttg attgcagtag ggttcctcgt tctctataaa atctgttcac
     6901 cgctgaataa attcagaagt cagatcattc ttttctgtgc tagcggtaac tttttttcgg
     6961 tcatcttttt gcataagctg ttttcaatca ccggtatctc agctgtatca cttttgctgt
     7021 tgagcattct atttttctcg gcagattcga tttttaggca tttgaccaca ttggtagaat
     7081 atttgtttga acgtaaaaat gaaaaagagc aaaagccgtt tagtcgcgta gctaaaaaat
     7141 ttctatcgat atttaaacga gaaaattgac gaaaagtatc tcaaaaaaga gtaaaaaaga
     7201 acaaccactc gtgtatcttt cgaagcagga tgagtcatcc aactttaaaa cgcacgagca
     7261 gttgctcttt tttacatttt cggaatggta acggtgaaag tcgaacctgt tccaagatga
     7321 ctgtctacag taatcgtacc attaaggagt tgcacgtagt cttttacaat cgctaaccct
     7381 aatccggtcc cgcctgaatg tcggcttcgc gccttgtcta cgcggtaaaa acgctcaaag
     7441 atccgttcct gatcctcaat gtcgatacct ataccaaagt cttggacaga aaacgataga
     7501 tcatctgttg cctgatagcg gataataatc tcgctgtcgc tttttgaata ttggacagca
     7561 ttttcaatca gatttttgat aattggataa aggatatctg ttttagtagt aaatggttcg
     7621 ttctttccaa tcaatcgaat cgtcaaccgt ttcttttcga tgattggctg ataattttga
     7681 acgatttgct ggaaataagg ttctgtataa attgtctgga tctcgtaaga attctcgcca
     7741 tcttttgaca gctggatgat ttcccgaatc agtttatcta accggatcgc atctttttgc
     7801 atgatctcaa gaaaagaagt cagagtttgc gggtcatctt ttgcaccatc cagtaaagtc
     7861 tcggtaaaac caatcagtga agtcacagga gtttttaatt cgtgagagac gttgccaacg
     7921 aaatcctttt gtagcttttc taaacgtcgc actttcgtta agtcatacgc cacccctaga
     7981 atctgtccgg taccttctga attagtaaag tagcgcaaac tcaagtctaa tgtctgccga
     8041 ccttctgtaa gggtgatctc ctgatggatc agcggatgct caggagtcac ttgatgaatc
     8101 agctgaatga gttttggctc ttgaatgact tctgtgtacc gctgttcagg ttgatagctt
     8161 accacgttta aatgtagctg catctttgga ttaagcagta gtaaacgaga atcagcatca
     8221 tcaatcagga atacgccaat catcagttcg ttcagtaacg tatataattg ctcttctgtg
     8281 gtagtacacg cccgatacat cttactcatt tgttcgctca acgcattaat cgtctgatac
     8341 aattcttccc attgatcggg tgtttgcatg attacttccg cctgattagg attttgcacc
     8401 atttttttta gtacgggcag cacggttttc aatggctggt ttttttgata gatcagataa
     8461 tagatcattc ctgcaagaac aaggaagaaa gacagaaaga agaaaaagac ccaacggcga
     8521 aaactctcag ttctcggtaa aaaaccgctt gtcggttctg cgatacgtaa aatggcttct
     8581 aactggccac tttttttgac tggtaatgcg acatataaaa gatcctcatt caaagtagta
     8641 cttttgcgca aagcgctacc taggttccca ccattcaata cggctttgat ttcgggacgg
     8701 gagtttcgct gttcattcaa tgtttcattg tttgtgtcaa ataagatctt tccagtagca
     8761 tccattaaag taatccgttc gttcgactga tggacgaatt cttccaaagc agttttgttt
     8821 tgcgctgctt ggaggttttc gacatctaat tgccggatca gcagttgtgc tttttttgtc
     8881 aggtagcttt cttgctgttc cacgatctgc tgttgaaaat aatgggaaat caattgccag
     8941 ccaccaaaaa acaaactaac taaaagaata agaaagaaga gacgttcata aatttttttc
     9001 catttcatcg ttttggttcc tgaaacttat agccaaatcc tctaatagtc accaagtact
     9061 ttggatgttt tggatctcgc tcgatttttt ctcgcaaatg actaacgtgt acatctacga
     9121 ttcggctttg tcctgcgaag tcaaaattcc aaatgcggtc tagcaatgtg tctcggtcga
     9181 tcacacggtc ttttcgtttc atgaaataaa caagtaattc aaattctttc ggtgttagtt
     9241 caatcagatg gtcgtctacg gtcacttgat aattggtcaa atcagcagtg atttgtccaa
     9301 tcgatagata ttcaggctca gcttcatctt ttgattgctt acgaggttca atccgtctga
     9361 atattgcttt catacgggct aatacttcgc gaggactaaa tggtttggtc aaatagtcgt
     9421 cagcacctat ttctaggcca atgatccgat ccacttggtc atctttagcc gtcagcatca
     9481 aaatcggtgt ttcatttttt tcttgacgca gccgctgagt gatctccatg ccatccatcg
     9541 ttggaagcat cacatctaaa atgatgaaat caaatgattg ttctaatgct aattctaatc
     9601 cttcgcctcc atctgtggca ctggttacct tgtagccttc tttttccaaa ttgaacgtca
     9661 agagcgttac aatagaaggt tcatcatcaa caactagtat ttttttcatt caaatctcct
     9721 ttaaataggt ttcattctgt ttatatttta gcatagaatc agtacaaagg gctattttac
     9781 aaaagaaata aatggtataa taggaaggca ctttgctgaa tagaaaggaa gagcagtcaa
     9841 tgattggaat cagtgcatgt ttaggcggtc tggcctgtcg ctatgatgga cagaaaaaag
     9901 aagtaccaga attgatggaa ctagttgaaa ctggagaagc tgtcatggtc tgtccagaag
     9961 tgatcggcgg attaccaatt cctagagatc ccgctgaaat cattggtgga aatggattcg
    10021 atgtgtggaa agatcaagca aaagtatgga cgacaagcgg cgaagatgta acggaagcgt
    10081 acaaaaatgg cgcgatcaaa gcctatcaaa aattgcagga aaaacacatt gatctagtca
    10141 tcatgaagga aaaaagccct tcatgcggaa cccattcgat ttatgacgga agtttttccg
    10201 gaataaaaaa aaatggtgcc ggagtggcta ctgcttattt tattcagcaa aaaatgactg
    10261 tgctctctga tgaagaatgg ctgaaaacta gaggtgagca gaatggaaat cgaaaagacc
    10321 aatcgaatga acgcgctctt tgaattttat tcgaccttat tgacagaaaa acaaatgaac
    10381 tacatggaat tatattatgc agatgatttt tcattaggtg agatcgcgga agaatacgaa
    10441 gtaagccgac aagcagtata tgacaatatc aagcggacaa gcaagatctt ggaggattat
    10501 gaaaaaaaac tccatctttt ttctaattat attgttcgag aacaggtatt ggaaaatatg
    10561 actgcatata ttacagataa gtacccggaa gataaaaaac tacttgaata tgtacagcaa
    10621 attcaagcaa tcgaagaata aataaaagga atgaagaaaa tatggcattt gaaagcttaa
    10681 ctgaacgtct ccagcaggcg atgggaaaaa taagaaaaaa aggaaaagta tcagaagctg
    10741 acgtaaaaga aatgatgcgg gaaatccgcc ttgccttact agaagccgat gttaacttgc
    10801 aagtagtcaa agattttact aagcgcgtac gcgaacgtgc ggtaggggca gaagtgctgg
    10861 aaagtttatc acctgcacaa caaatcgtaa aaatcgttga tgaagaattg acgatcacac
    10921 ttggttctga aacagcagag ttaaataaat caccaaaaat accaactgtt atcatgatgg
    10981 ctggtcttca aggggcaggt aaaacgacct ttactggtaa attagccaat tatttaaaga
    11041 aaaatgaaaa tgctcgtccg ctcctaatcg caggggacgt atatcgacca gctgcgatcg
    11101 accaattgaa agtattaggt caacagctag acgttcctgt atttgatatg ggaactgaag
    11161 tcagcccggt agagatcgtc cgtcaaggga tggagttagc aaaagaaaag aaaaacgact
    11221 atgtattgat cgatacggca ggacgtctgc atatcgatga aacattgatg gatgagttga
    11281 aacaaatcaa agaattgacg caaccaaatg agattttgct tgttgtcgat gccatgactg
    11341 gtcaagatgc cgtcaacgta gctgatagct tcaaccagca attaggtatt acaggggtcg
    11401 tcatcactaa acttgatggg gatactcgag gcggggcagc actatcgatc cgctcagtga
    11461 caggcgcacc aatcaaattc atcggttctg gtgaaaaatt gactgactta gaagtattcc
    11521 acccagatcg tatggctagc cgtatccttg gtatggggga tatgctgaca ttgattgaaa
    11581 aagcgcagca agactacgac gagaaaaaag cggaagaact tgcacagaaa atgcgggaaa
    11641 attcattcga tttcaatgac tttattgaac agcttgatca agtgatgggt atgggcccac
    11701 tggaagatct aatcaaaatg atcccaggaa tgaatcaagt ccctggaatc gaaaacgtca
    11761 aggtagatcc aaaagatgtt gaacgcaaaa aagcgatggt ttattctatg acgccagcag
    11821 aaagagcaaa tcctgatctg ttgaacccaa gccgtcgtcg ccgaattgct gccggttctg
    11881 gaaacagtgt tgttgaagtg aatcgaatga tcaaacaatt caaggaatca agaaaaatga
    11941 tgcagcaaat gtccaaaggg gatatgaaca tcccaggtat ggaccaaatg tttggttcag
    12001 gcgtcaaagg aaaactaggc aaaatggcga tgaatcgaat gatcaagaaa aataagaaga
    12061 aaaagaaaaa acggaaataa gatgaaaaaa acagcttcgg tacagactga aaatgtctac
    12121 tgccggagct tttctatcag caatttttat tctttactaa tacaattact ctaaacgaag
    12181 aggtggcaca gatgagatgt ccgtggagtg aacaaacaga aagtatgcgg caatatcatg
    12241 atactgtctg gggtgttcct gaatatgatg accaaaagct gttccgaaaa ttgatgcttg
    12301 atattaatca agccggattg agctggcaga cgattttaaa taaaagtgaa gcattcgatg
    12361 aagcatatga tcgattcgat atcaaaaaag tcgcaaatta tggagaaaca aaaatcagtg
    12421 aactaatgga aaacaaagga attattcgta accgaagaaa aatcgaagca gccgtccaaa
    12481 acgccaaagc agtcttgaaa attcaagaag aaatcggcag tttttcagag tatctttggt
    12541 cgttttctaa tggaaaaatc gttgattctt cttatcattc acaagaagaa gtcccaacaa
    12601 caagtcctct ttcagatgaa ttagcaaaag atctaaagaa aagaggattt aaatttatcg
    12661 gaagcacaac aatctatgct tttttagaag ctgtcgggat catcaatgat caccttgaca
    12721 gttgtttccg caaagaagag gtcgtacgta tcggcagaaa gggcgaataa agcatgcgaa
    12781 aaatcatatt ttatggtgct ataagtttag atggctattt ggcaacgaaa acggatgatc
    12841 ttcaatggct ttttgacact ccaacaggta agcaaactac ttatgaagct ttttatgaaa
    12901 caatcgatac gaccatcatg ggcagaaaaa cttatcagga agcaaaaaaa tatttggaga
    12961 ccgaagcaat ttatccagag aaaaagaatt tcgttttttc cacccacgca caattacaat
    13021 tgccagatgc tgaggtcgta aacgaagatc ctgttgcttt tctaaaaaat ctacaaatga
    13081 cagaaggaaa agatatctgg gttgtgggtg gcggtcgatt gatcaaaccg ctattggaac
    13141 atcaaatgat tgatgaatgg tatatccaga ttacccctgt attattaggg gacgggattc
    13201 ctttattcca aaaaggaaca tatgaagcgc gttttgaaat gctagacacg acacgattcg
    13261 gtgaatttat cgaattgcat tatgtacgaa agtagaagta aataaaataa aaaaggcaac
    13321 tatatgcaga aatgtcctgt acatagttgc cttttttatt accgttatgc tttttactct
    13381 gttaatttgt tagaaaaatc tagatacgca tctaaaatcg tttggaagaa acttaatgtt
    13441 ccttcaacga tattaccatt ttcatcaatt agattcgcaa cgtttccgat atatgcttcc
    13501 ggttgctgca aggttggcac attcaaaaag acaagtgatt ggcgtagatg gtggtttgcg
    13561 ccaaagccgc cgatcccacc tggtgatgca gtaacgacta aacctggttt atgatcccaa
    13621 acactgtgtc cataaggtct tgagcctaca tctaaagcat ttttcaatac tgctggcaca
    13681 gaacggttgt attcaggagt aacgaaaacg acaccgtcta gtcccctcac ttcctcacga
    13741 aaacgagtcc attcagcagg agcctgttct ggagtttcga gatcctcatt gtaaaatggc
    13801 agatcatcga tttttacaaa tacactttcg tacccttcag gaagcaattt cgcaaaagct
    13861 tctgctactt ttttgttgta agaatctttt cttaaactac caataaaaaa tccaattttt
    13921 tttgtcatac gatttttcct ccttcaaact atctataata atcttacaaa agataagtaa
    13981 ctggagcaaa taaaaacact tactgacaaa agctacatag aagatagatt acttattttt
    14041 aacaaaaaag aagtctaaaa tcttctattt tctaaaaaaa atcgaattta atcaagctgt
    14101 aaagaaaaaa agctttacag ggtaaaaaaa aactgttaca ctacatcttg tgaataaaac
    14161 aatggaggtg gaaataaata atggcagtta aaatccgttt aaaacgtatg ggttctaaaa
    14221 agagtccgtt ttaccgtatc gtcgtagctg attcacgttc tcctcgtgat ggacgtttca
    14281 tcgaaactgt aggtacttac aatcctttga aagaccctgc agaagtagtt ttaaaagaag
    14341 acttagttct tgactggtta tcaaaaggtg cacaaccttc tgacactgta cgtaacatcc
    14401 tttcaaaaga aggcgttatg caaaaacacc acgaagctaa attctcaaag aaataaggtg
    14461 accggatatg aaagatttaa gcgacttagt cttaacaatc gttcgtccgc tagtcactta
    14521 tcctgatcaa gtcaagttag acgtcgtaga gtcgaaagac ttttacgagt acaatctaac
    14581 agtggctcct gaagatattg gccgtatcat tggaaaacaa gggcgtgttg ctaaagcaat
    14641 ccgcacaatc gtttacggtg ttcggatcaa tgcaccgaaa aaagtgcgtt tgaatatcat
    14701 cgatgataag gaaaagtaaa taaacgtgct gtactcgaat tttcgagtgc agcttttttg
    14761 ttttttttat taattgaaga aatgattatt tggcaaaaca agcaagaaag cgtatcctta
    14821 taggaggagg gagtgaacag ccaatgagaa agaaaatgtt atttattcca tttgctctat
    14881 tgttaagcgc ttgtagttcg gttactcaag aatcagacaa tacacatcta tcaagcagta
    14941 tatctgaaac tgttaccagt ccagaaaaaa gtagtaccaa aacggcttcc accactgaac
    15001 aaacaatggc tacctcaaat aatgagaaaa agactgcttt agaccagttg aaagaacaac
    15061 agccaaatgt tcccatgcct ctagatgtac cagtctcttc aggctatctc aatatcgcag
    15121 cgacacatac aaagcaaggt tattctattt tatattacag aacagatcgt cccctcgggt
    15181 tgaatgctga cgaattgaat caagaaacgc ctattgcaac ctatctatat caatatgggt
    15241 ttgcttctag tcaagaaaca atccaagttt tgcagccatt tgagatcgac acaaatggtc
    15301 agcaagtgga cttaggttct cgaatcacag ggtatcagca aggtgcagca ggttcaagtt
    15361 ttcttgaatg gcaagaagga aactggcgta ttcgaatccg tgggaataat atagaaggcc
    15421 aagatccctt actattagct aaagaaatcg tagcttattt ggaagaaaac agtctaccag
    15481 cacctgaaca atttggtaaa attactgttg atatgggtga tacgacgaat cgagccgtag
    15541 aagtaagctg gcaagaaccg aaaaatgcct atacgatcac tcatcaagat cctatgtctg
    15601 cgttgaagat ggcagtttct atgaagaggt tgtgaaatca gcgcgctgat ctgagcccat
    15661 catttaactc caagtcacag gaagtaatca aaaatagcac gccgcatttt tgcataattt
    15721 tggcttaata ccttaaaaga aaactagaat tgcctcttca cacatgctaa aataaaacag
    15781 acaaaaaaga aatggggata taagttgact gaatacttga atgtaggaaa aatcgtaaac
    15841 acacaaggta tcaaaggcga agtccgtgtt atctcaacaa cggatttccc agaagaacgt
    15901 tacaaaaaag gaacggtgct aacactattc caagacggaa aagcacctgt ggaattaaca
    15961 gtcaaaagtc atcgcaaaca taaaaatttt gacttattga gttttgaagg acatccttct
    16021 atcaatgatg tggaaaaata tcgggatggc atattaaaag tgtcaaaaga caactctgta
    16081 gatctagctg aaaatgaatt ctattaccat gagatcatcg gtctgcatgt attagaagat
    16141 ggaactgagt taggtaaagt aaaagaaatc ttgtcaccag gtgccaatga tgtttgggtc
    16201 gttcaacgtc cgaaaaaagc tgatatattg cttccatata tcgcttctgt cgtcaaagaa
    16261 gtcgatttag aagctggagt ggtccgtgta gaaattccag aaggactgat tgacgatgaa
    16321 gattgatgta ttgactttat ttccaagaat gtttgaaggt cctatggggg aatccatcat
    16381 cggtaaggct gtagataaag gattattaga tatcaatatc tctaacttcc gcgattattc
    16441 agataacaaa catcagacag tagatgatta tccatacggc ggtggagcag gtatgctgct
    16501 caaagtccag cccatctatg ataacatcca agccattgaa aaagctgcac cggatgtcaa
    16561 aaaaagagta attcttcttg acccagctgg taaacgattc gatcagaaaa tggcagaaga
    16621 attttcacaa gaagaacact tagtattcat ttgtggtcat tatgagggat atgatgaacg
    16681 tatccgcaca ttagtgacag atgaagtttc cttaggagat tatgtcctta ctgggggaga
    16741 attaggtgcg atggtcatga tcgatgcaac agttcggctt ttgccagatg tgttagggaa
    16801 tcagacttca gctcaaacgg attcttattc aaccggttta ttggaacatc cccaatatac
    16861 tcgcccggca gaatataaag ggatgaaagt accagaagta ttgacaaatg gaaatcataa
    16921 attgattgaa gaatggcaat taaaagaatc actaagaagg acctatcaac gtcggcctga
    16981 tcttttggaa acacttgaat ggacacctca aatgacgaaa tttttagaag aaatcaagaa
    17041 agaagaacaa gaaaaaacag cagatgaagc caagtgactt tttctaaaat cttctttaca
    17101 gtaggttgat aatatgttag tattttatgg tgagtgcaaa agcacttaac tattacgata
    17161 ttccgctgtg agaaaagctc ataagaatat ttggaataag gagaagaaaa ccatgaatcc
    17221 attaatcgaa gaattaacaa aagaacaatt acgttctgac atcccagcgt tccgccctgg
    17281 tgacactgtg cgtgttcacg caaaagttgt tgaaggtact cgtgaacgta tccagttatt
    17341 tgaaggtgtt gttatcaaac gccgcggtgc tggaatcagc gaaacttata cagtacgtaa
    17401 agtttctaac ggagtgggcg ttgaacgtac attcccattg catacaccac gtgttgcaaa
    17461 aatcgaagta gttcgctacg gtaaagtacg tcgtgcaaaa ttgtactacc tacgtgcatt
    17521 acacggaaaa gctgctcgta tcaaagaaat ccgtcgttaa tcatcgttat cagacagaga
    17581 aagaaccctt ggtattcaag ggttcttttt ttattatctg tttttttata ttaacgattt
    17641 ctatttggta catttttgat taataaaaag gggcaaaaaa ggggcaacaa gttacagttt
    17701 ttctatatct tctttcaatt tttcttttac tccttttgtc acatgcaaat aaattttttc
    17761 agtgatatca ctattttcgt gaccaacgcg atcctgaatg gcatacagag gagttcctag
    17821 ttccgctaat tttgaaatat gggtatgtct aaaaatatgt gaactaagtt ttttatcaat
    17881 cttcatgtca gctttatgac ttctcaaata ggtgttaatt gctgttagtt ggaaaggagt
    17941 tcctttcgtt gtttgaaata gaaattgacc atttggattt aattctagaa gctcattgta
    18001 aatagctatc gctttttttg gtaaatcaat ttctcgcatt ccggcagctg tttttgtaga
    18061 atcagatttt ttcatatcag ctattgaacg ttctctatac atcatcgtcc catttataac
    18121 tactgatgca ttattattgg taatgtgtac atcatcttta cttaatgcga ttgcttcacc
    18181 agacctcatc ccagtcaaat atagccactg gaaaaggaga gaatatcttt tattgtgtga
    18241 agttgtgaaa tctactagtc tattatattc atcatcttct aaaaatttat ctttaatttt
    18301 tatcgttttt gactctcttt tataatcaat aactacttca tcgataggat ttttttctac
    18361 ataacctttt ttcatagcat atgaaaaaag aagattcaat ttggatttaa ttacactgac
    18421 gtacttattt gacaagtcat ctttatatat catgtcttca aaaatattat tcaaatctat
    18481 tgtattaata ccagaaacga tgtaagtctc aggtatcttc ttctttatag tgtttaatat
    18541 attattcgta ggataatatg tagattcctt aacttgtctt ttgtatataa ctaaccattc
    18601 ttcaacaagc tcatgaaatg ttagatcagg cttatgaagt gttttttcgt ttaattttat
    18661 atcaattttt ttatttaact ctagcaatgc cactttctga gtttctcgag atttattttt
    18721 ataagtaatg ctcacttttt ttctttttct agtttttgga tcaatatatc gctcattata
    18781 tttatatact ttttttccgt ttttatcagt tttagtttcg atccacattg ttttcatctc
    18841 ctatttgttg ctataatagg aatagataag taagccgatt atagcaggtt tatttttcat
    18901 cacgtccaca aactttggcg agggaggggc gtgtttttgt tagttattgt ggtaggttat
    18961 ctaaagcgta ttgtgcttgc tcatttgtaa aaccttcaaa tataagttga tcgtacaatt
    19021 gcgaatctga cattgatgcc caatcatcgt aactttccgc tttagccaaa gcttgttcgt
    19081 tgtaatcgac atcaacatta gccagcgcat aatcgattgc atcacttgga tattcttcaa
    19141 actctagttg ttcacgcaaa ccttgttcag acataccagc ccaacctaga tagctttcag
    19201 ctttgctcaa tgcatttctg tattcacgag gaacactttc ttcttgagta acttcttcta
    19261 tagtagtttc agtagtttca gtttcttctt caacgactgt agattctgct accgattctg
    19321 cagaagacac ttctgtcacg ctttctttag ttgtttcagc gacggtattt ttagcatcat
    19381 cactgcctcc ttgcgaacct atagcaataa acaccacaac aaccgctaac aaccaaaacc
    19441 atacccgttt ataaaacggt ttcttaactt tatacatttt cccatcttga cccataactt
    19501 tttttgccat ttaaatatcc ctcgcttctt gttataatat atttgtgatc tcagaaatga
    19561 ggtatgagtc cgtgttgcag cacgggcttt tttctttata acttttttag agattatagg
    19621 caaaatagta gggcataaaa atgtattatt gaattccgta tttagaaaat cctaattgaa
    19681 cttcaccgga agtcttttgc tgtgttgtac gcaatgcttc ttcttcagac attccattct
    19741 gtactttcca tgcaacaggc gacatcccgt atttgttaac aaaatcagta agtgataaag
    19801 tgtcagcgtc ttgctgagcg cttgtttgtt ggtcttctgg attctgttga gatgctgctt
    19861 gttgttcttt ctgatcttga ctgataatat tgccagcatc atctgtagtc aatccatttt
    19921 cataaagggc cacgccgaaa gcttcccact ctttgttgga ccaatttgca cgatcagctg
    19981 gagttgactg taaagtgcgt tgtttcatct gttcatatgt ttcttcttga ggtgcggttt
    20041 ggattgtact ctgactggag cttataactg ttgggctagg ttccgccgta gcttggttgg
    20101 agcttgtaac tgttgaacta gaatctgttt tagatgtaga tttgctagta gatgaactgg
    20161 tttcagttgt ttcttttgtt ttacttattt ttgtttcttg gttagaagtg gtatctgttg
    20221 attcagcttt tttattattt gaacaagctg aaagtagcag agcagtactt aacaacaaca
    20281 taacgctaac ttttttcatt ttataattcc tctttctcgt tgtaatatgt gtgctaacac
    20341 gggctttttt atataagaaa acgataagcg ctttctggaa gcccgtaaag attctttaat
    20401 tcctcgattt ttttaggata ttgatcatta tcttctttat aaagagaaac aatgagatta
    20461 gcagcaaagc aattagcttc gctttcagat ttgcttctag atgttcttgt tgatacataa
    20521 tagctggata agccacgatg aaaaatagcg tgacctaatt cgtgagcgca aatgtagaat
    20581 ctttcctcag agtctcgcag ttcatcattt aaaaagatta tcgcacgatc tctaatttct
    20641 tgaaactgcc ccttgggatt ctcgataaaa ggaacgtatt gaattttaat gcccatcttt
    20701 tcacaaatat aaaaaggatt agcggactgg tatttccgct tcaactcctc gactaaatta
    20761 atcgtatcca tctccataag ctcacatctt tttgcctttt tctttgtctt ctttcacaat
    20821 atcccagaaa gtcgctatca ggatatcttt tacgcgctgt atttgttcgg gtgtcaatgt
    20881 ttccccacca taagacatat taacatttga gtctagtagt ttatcaagtt caaccacttc
    20941 ctcttttgta gcccacttgg gaacattatt atttcccaat aaataatcag ttgtgacacc
    21001 aaaataatca gcaactttct ttaagttctc agattttggc gaggctttat cccatcttct
    21061 tatttgtcca ttagagatgc ccacctgtct ttctacttct gctatagtca catgcttttc
    21121 gtctgctaat tctttaatct tagtaactaa actcattatt atcaaccttt caaagctgaa
    21181 aagaaaataa atagcttaaa agttatattt ttggttgaca attagctttt aagctagtat
    21241 atttaattcg taagctaaat tgttagctaa ataagagcaa caaaaaactc tactaattta
    21301 aaacattctc tcggtcgcca aacttagaaa tgttatttta gaggcttttt ataagtctta
    21361 tttaactatg tattcataat agcttaaaag ctaataggtg tcaacgattt agctaatttt
    21421 ttagcttaca aattatttgt ttagaaagga gctattttta tgtctgagaa tttagactta
    21481 aaaattcgag cggagatgag aaaaagaaga atgactttca aagaactagc tgcgcttatc
    21541 ggtatttcag gagcttattt atcagatatt ctaaacggca atcgtgatgg aaagaaagca
    21601 caacagcata tcgaaacagt gaaaaaaata ttggacatcc gatagggggg gtaggcgatg
    21661 acaaaactaa aaaaacaaga ttttgtaaaa aaatataatt attctccatc tacttatcaa
    21721 cgtcgaatgt cggaactaaa aaatacagca attttctcag cggcgtatga acgggtcaca
    21781 ggacaagaag tttggatcaa tacagaatta tacgataaat ttttgtcttt caaatcctat
    21841 aacaggttac gcacaagaaa ggtaacacct aaagaattta tcgagaagca tttagttgat
    21901 ttataaaaaa cagaacattt tgagaggtga aggttaatgg gtaaattcaa cagagcatta
    21961 gtattcagcg caccgctaat cgtctatgct ttagggcttt ggggaagtag acaagcgttg
    22021 ataggaacga ttgtgtacat ggtttggatt tttatagggc tggatgaagc tgagtacaaa
    22081 acaaaaaagc cagtcgggag ggactgacta atgagtaagg acgatattgt atttctgtta
    22141 attatgtttt gtgggattgg atcaataata attaatttgt atttgattat taaagaaaaa
    22201 tttttcaatt aaaatgagtc ttttagcttt aacttaaatt ttttttgata attagctgtt
    22261 cttatgacca ttacaagttt ttcaccaggt aatatatctt tcatatctaa aacttctgaa
    22321 aaagcgactg agtagccagg agagattgct tgtgccaacg gtataggaga taaaaggcta
    22381 cttttatgaa tgcttcccat atcaaaacca ttggcgtgat aatgtgaaca attaattttc
    22441 ttaccgttgt aaagatacgt acattcgata attgagtttg gcatttttga tgggtttgca
    22501 attacgccag taagaatcat tcgattactt ctatcatgct taactaaaaa ataggagagc
    22561 gtaatttttc ttttatcttt aaataagtta tagagggata aaaaaaatcc tgaaatagaa
    22621 atgattaaag taatagcgac ttggtaatcg ctcaaaattt ttatcaagta attcaccacc
    22681 tttttactca aattatatca aaaaggagag aagaaataat gcaagaatta gtaattttga
    22741 aaaataaaaa aagacacgaa cgccggcaag catgatcgtg tcagggaaat aaactatctt
    22801 tctatatttt accacagaaa ggaatgaacc gtaaatgcta attgcaacgg atacactaga
    22861 ccgcatcttt ttaaaagacg aatacaaact gcgcaatata gatgcgtcag gaattttagt
    22921 atttgatctt tatgacaatg gaaaaattgg tatctatcaa gcaagtgata ttgaagaaac
    22981 aaaccttgct ttcgaacaaa ttgatgattc tgtggaattg gatttagatg aggcaatcct
    23041 agcttttgaa caaattgcaa aattattaaa ggaggcacaa aagaatggca actctttacc
    23101 aactcagcga gtcatatatc aaagtcctgg aactggcaga acaattggat gaagaaattc
    23161 ttcgcgatac tctcgattcg attaatgaag cgatcgagta taaggcagaa aacttagcaa
    23221 aaatagttaa agaagtagaa gggaaagctg agttaatcga tagtgaaatt aaacgtctgc
    23281 aggaacgtaa gacatcgctt ttgaacaatg ctaagagtat caagcactat ttacaagagg
    23341 aaatggaaaa gactggtaaa acgaagatta aaggtgaatt attcaacatt ggaattcaaa
    23401 ataatccagt atcggtcaat gtaatcaatg agaacttaat tccaaaagga ttctttaccc
    23461 ctgtgcctcc caaattggat aaaaagcaat tgaaggagga actgaagcac ggagatattc
    23521 ctggtgctga actcgtccaa acaaaaggtt tgaggataag atgatgaagg aggagaaata
    23581 atggaacacg aaaacgtaaa agacgctttg aaagctgcta tcgaaatcgc ggaagctaaa
    23641 ggaataaagg ttgacggcaa accagcaact gtccatgaca ttcaaaattt gacgaaagaa
    23701 catctttatt ttatcgccga cttgcttggt ttgtcggaat tgtatttaga caaataaccc
    23761 cacacggaag gagtggctag ggtggttgta ttacaagtaa tagtctgcgt aacattcatt
    23821 tggtcgtgca taccggtttg tatatatatc atgaagaagc ttcgccctga gtcttacaaa
    23881 ttatacgcaa tttacagcat aacagtagct cttgcattta cattgtttgc aatttctagg
    23941 cttccgtttt aatcgtggga atgaattttt aatgaactaa attatctata aagcaaaaaa
    24001 aggagaaaca acattgaaaa acaaactagc aaaaacaaca gcaatcatcg gactagcact
    24061 aggtagcggc gttatcggct acgcagcaag caatgcgttt caagatttgg acacgatcaa
    24121 agcaaatttc aacacagtcc tacaatacgg tcaaacgaaa tcgcaacgtg tgtcagaact
    24181 tgaatcacag ctatccaaca acactcgcac acaggagcag ctgaaagccg aaattgagca
    24241 aatcaaatcg gacaagcaga aggaaattga agccaagcaa cgagaaatcg aacaaaagca
    24301 acaggagatc gctacaaagc aacaggaagc cgatagcttg cgccaacaac tatccacagt
    24361 gcaaaacgac aaggagcagt tagaacagcg cgtgagcgag ttacggcagt atacggatca
    24421 aaaggtaggg gagttgggga aatgaaagag ttgactattt atgacccaaa tatttcatgg
    24481 gctaaacaca caattaaagt ttcttttatg atttggggtt acaaaggata tgttacttac
    24541 aaagtgggcg gtaacactaa gggtttatca ttaatagcta ttgattcaga tgatctatat
    24601 gatgctaatt tcgaggataa cccagttaat ttccgtgacc ttgatgaaga ttggttctct
    24661 atggaactta ctaacgataa aggcgacagt acacttgtag aagatgaatt cgacagacta
    24721 ggtgattata ttgtcggtgt tgaaattatt gcgcacgaac cagagtagga gagtgaatac
    24781 aaaatgatta aaagaatcac tatatcagtt gaagaagata gtggatcaac aatgcagcat
    24841 accgacaatc gaaaaacttt tttaaccaat agaaaggaga attttgatgc agattaagaa
    24901 ggcgacggat atcgaacaaa ccaagggaac atatttgatc tacggtgctc caggaaaagg
    24961 taaaacttca acggctaaat attttccagg gaaaacactg atccttgata ttgatcggac
    25021 ttcaaaagtc cttagaggtg agaaaaatgt cgatatcgta tatatcgaca acgaagatac
    25081 ctggaacgac tggggcaaca cgttggctga tttaactacc aattatgtag gtgtttatga
    25141 caacgtggtt gtcgataatg tcagcgaatt ggaacggtgt attctgtcca gtttaggcgc
    25201 agaaggaaaa aacaacggcg ttccttcgca aggcgattat caatatatgc aatttagaat
    25261 ggtgaacagc ctacgctata tgaaaaattt agacagcaac cttatctgga ccgcatggga
    25321 agaaatcgat ttgtggacgg attcggatgg atcttcttac aacatcgctt tgccgcagat
    25381 caatcgaaag attcgaaaca atattttggg attatgtgac gttgttggtc gattgatggt
    25441 aaaggaagac gatgaacgcg gatttatttt acaagccaca gattcaacct atgccaaaaa
    25501 tcaattggat aatagatctg gctgtaagca aagtgagctg attttatatg gaattgtacg
    25561 actaccagaa tgatttagtc gatcgtgcaa gacaagccta tgttgatggt tacaaggcac
    25621 catgtatcgt atcaccgtgc ggttctggaa aatcagtcat ggttgcagag atcgctaaac
    25681 gaaccacacg aaaaggcaac agagtgttgt tcttggtcca tcgtcgtgaa ttgattgatc
    25741 agatcaaaga tacgtttcaa aagatgggcg tagataatca gcttgtaaat ttcggcatgg
    25801 ttcaaacagt cgtacgacat cttaaaacca tcaagaaacc acaactgatc atcactgacg
    25861 aaaaccatca cgggttagca gcgtcctaca gaaaaatcta tgagtattat tcggacgttc
    25921 cgcgattagg ttttaccgcg acacccatcc ggttaaacgg tagtgggttg ggggatgtga
    25981 acgacttgct aattgaagga gtatcggcta aatggttgat tgagaatcat agattagctc
    26041 cttatgaata ttatgcacct aaattgatcg atacagccga attaaagaaa gcttcgactg
    26101 gagattttac aaagaaatca atggataagg cagtgaagaa tactatttat ggcgacgtgt
    26161 tgaaacatta taaaacgtta gcagaaggtg aacaggcaat agcatactgt cacagtatcg
    26221 atgcaagtaa acacactgct gaaatattca acgatgctgg ttataaagca acacatatcg
    26281 atgcaaaaac tccaaaagat gaacgtgcag atattatcga agcgttcaga aatcatgaaa
    26341 ttaaaatcct atgcaatgtt gatttgatcg gagaagggtt tgatgttcct gattgttcga
    26401 ctgtaattat gttgagacct actcaatcgt tatcattgta cattcagcaa tcgatgaggg
    26461 ggatgcgtta ccgaccagat aaaacgtcaa tcatcattga ccatgtgggt aatgtgaacc
    26521 gttttggatt gcctgatatg gatcgtgaat ggagtttaga tacaaaaaag aaaacaaaaa
    26581 ctgatagtga tttatctatc gttcaatgcg cgttttgttt tggtgcttac gaacggccaa
    26641 aaggcgataa tatttgtccg tattgcggag agttgcagcc gattgaagaa cgaaagtcag
    26701 agttagaaat cgatgaatcg gctgaattaa tgaaagtcgg agaaacgaaa attactttga
    26761 attttgagaa caataaatat tacaacatga cggaagatga agcagaaagt atagaggact
    26821 tatatgccat agcaagagct aaaggattta aacctggttg ggcttatatg gctgctaaga
    26881 ggaaggggtg gttgtaggaa tgggcggtat ttttggtaaa aaagcagaag atgttcaagg
    26941 ttcaataata aatggcgtaa caataatagg tgatactgga aaaagagata gttcaggcaa
    27001 tcaaattgta atcgctagaa ataaaaataa cgaagttttt gaatcttctc tatctaatat
    27061 aaaaagaggt gttgttaacg ggacaggcga agagagtggc tacgttaatt taaaaaaagc
    27121 taatgaaaaa taccatgttg aaggaactta cgttaaggct ttgtctgtcg gtggaacaaa
    27181 aggcgttaat tgggataaac gaagaaataa atggaaagca cgattatatt tcaaaggaga
    27241 atatgtctta caaaaggatt tcaacaccaa agaagaagca atccaagcac gacttgcagc
    27301 agaagaaaaa tatttcaaac ctatcttaga aaaatatgaa aataaaaagg agaatgatta
    27361 acatgacagg atttaactta gacttttcaa aagcgcaaca agggaacgaa atcaaagacg
    27421 gtacgtacga agtggtcgta aacaaagctg tagaaaatgc aactaaatca ggcgcagaat
    27481 ttatcgatat cgatttgatc gttcgtaacg atgtggatca accgttccaa aataaacaca
    27541 ttttcgcaaa aatctggaaa gccaaagcta ccggcaaata taacgaaggt atgatcatgg
    27601 caattgcaca agcgctacag ttggaagacg gaaaatcata taacgggttt gatgaattgc
    27661 tggcggactt tgttttgaaa accgcctcag tacgcgtgaa aactgaagag tcaaatggat
    27721 ataaaaacgt caatgtgaag tcttgggata aaacgaacac acggggcgta atgaatcacc
    27781 aattcaaaaa tggtgatgaa ccatccttcg gaccggaacg ttcaagagcg acaacggtta
    27841 gaaatgacaa tcttccattt taattgaggt gtaatcaatg tatgaaaaaa ttccaaaaga
    27901 gcttaaaaat ctcaaacaat ggtgtgttta taagctagtt tgggatgaaa agcggcagaa
    27961 gcacacgaag atcccttata acgccaacaa cgggcataaa gccaaatcca atgacgagag
    28021 tacctggtct gattttcaga ccgctctcgc tgctattgat cactacggaa tgagtggact
    28081 ggggttcttt ttcaaaccac cttatttcgg cattgatatc gataatgctg aaggtgaagt
    28141 tgagcgattt aaatcaggtg atatagaaga aaatattatc tatgaattta tcgaaagcat
    28201 gagatcctat gctgagtatt ctcaatcagg tactggcatc cacattattg ctcgcggaga
    28261 attgcccggc ggaagacgca ggaaaggtga cgtagaaatg taccagaacg gccgattctt
    28321 cgttatgact ggaaatgccg catcaaaata tttagaaata actgagccga atccaaagga
    28381 tatcaaacgc ctatatgatc gctacgttgg agatgaaaaa atcatccaat tcaaagaaga
    28441 aaatccgctg atgaataccg ttgatttacc ggttgaagaa attatcaaac gtgctgaatc
    28501 gtcttcccaa ggggcaagat tcaaagtctt tatgaacggc ggttgggaag ctttttattc
    28561 ctcgcaatcc gaagcggata tggcgttcgc caacgacttg gctttttgga ccggtagaga
    28621 ctttgaaaaa atggatgaga ttttcagagc gtctgcaatg atccgtagca aatatgacca
    28681 aaaaagggga tcggcaactt acggagaatc tctactaaat aaggcaattg ctgatacaaa
    28741 ttccgtctac aaccccaaac ggaaatctga ttttaagatt tttatcaaag accaggaaca
    28801 gccaaaagag gaaaaatact attcgtacga cgacaccggc aacgcggatc ggtttactga
    28861 tatctacgga acgttagtca aatattcgta cattgataaa tcttggtatt actacgatgg
    28921 gaaagtttgg ctacaggaca ataccggcga agttcggaaa atgatcgata cgacagtaga
    28981 catcatggga aaagaaccgt taacgatccc tgaaggcgca gacgatgaaa ccaaagaagc
    29041 tttgatgaaa gcgaaagaaa aacacgtcaa gcgttctcgc agcaatgccg gaaaaaacgc
    29101 tatgatggac gaattgaaac atcgactatc cgtattgccg gaagagttcg acaaagataa
    29161 aacgctgttc aacacacaaa gcggctatct gtctttgcat gacggtcttc tacacgagca
    29221 tgagatagac aaaatgttta cacgtgtttc aaatgtcgag tacacagaat cggtcgattg
    29281 tcctatgtgg gaagaattta ttaatcagat ttttgacaat gatcaagaat taatcagata
    29341 tatccagaaa tgtgtcggat attccctgac cggatctacc ggagagcaat gtatgttcat
    29401 cctctacggt catgggtcaa atggaaagtc ggtatttttg gaaattattt ctgaattgat
    29461 gggaaactat gcgatgacta tgcaggcaca aacgatcatg gtcaagcaaa gccaatcatc
    29521 agcaaacagt gatattgcac gattgaaagg tgcgcggttg gtcacttcgt cagaaccgaa
    29581 tgaaggcgtc cgactggacg aaggtctggt caaacaattg actggtggtg ataaagtcac
    29641 ggctcggcac ctttatggaa aagaattcga gttcgaacct gaattcaagt tgtggctggc
    29701 aacgaaccac aagcccatca tccgtgggac cgatgacggc atctggcgac ggttaaattt
    29761 aattccattc actgtccaaa tcccggatca caaaaaggat aaaaatctga aatttaaatt
    29821 gcagacggag ttgcaaggga tccttaaatg ggcaatcgat ggttgcctgt tgtggcagag
    29881 agagggcttg gagaaaccaa agtcggttgt tgcagcgagt caggattatc gaaacgaaat
    29941 ggatcaaata ggtacattta tcgaaacgtg ttgcgaaaca ggtccaggac taaaaatatc
    30001 aggcggagaa ttatacaaag tttatcgtga atgggcatca gataatggcg agcatacttt
    30061 cactaacacg aagtttggca gagagatttc aaagaaatat agcaaagaaa aagctggtgg
    30121 atttatggtt tataaaggaa tcacattaaa accaagaaaa tacgataacg ttagagaact
    30181 ttttaaataa atctggaggg ttctggaggg ttgagaacga aaccctccaa cccttagaaa
    30241 cgttgatata tcagtattta tattatattt ttctttcttt ctggagggtt ttaaaaaaat
    30301 aataaagtat taaagtaaaa aataaaaagt aaattatata aaaaagaata ggtttttggg
    30361 tctgaccctc caaactctcc accaaaatct tcctaaatgc tttgatacca acgattaaac
    30421 agtctggagg gttacattga aatcagaaca tcaaatacaa gacgagatca gaattgcctt
    30481 atcaaaacat ggttgcacga tttttcgatc caatgcggga caagtgacaa cgatcgaagg
    30541 gcggcaattt tacgggatgc caaaagggtt cccagatcta tgtggacatc gtaattctga
    30601 tgggaaagca atttatatag aagtaaaaaa tgaacgcggt aagttgcgtg aagatcaaaa
    30661 aaggtttgct gaatttttaa acggtcaacc tgtactatac ggtgttgcac gatcagtgga
    30721 agaagcattg aaaattgtgg aggaatcatc atgacaacag aagaagtgat tcaaatgcgt
    30781 attcgaagcc ttcagcgtga gattgacgat ctggaacgga caaaggcagt gatggtcaat
    30841 gaaacggcga ggaaggcaat cgatgtgcac atagagaatt taagaaggga aatccgtaga
    30901 ttggaggaat gagcgtggat aaggaagcgg cttggcgaaa attaatgttg ctgattcaag
    30961 atgagaactg gcaagaagat gaagcagtgg ttgctgaagt tcagcgtcta g
//
LOCUS       DAFEEZ010000032        30350 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000032
VERSION     DAFEEZ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.032"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            171..515
                     /locus_tag="LP245_001518"
     CDS             171..515
                     /locus_tag="LP245_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBL1519443.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            516..935
                     /locus_tag="LP245_001519"
                     /pseudo
     CDS             516..935
                     /locus_tag="LP245_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(1027..1377)
                     /locus_tag="LP245_001520"
     CDS             complement(1027..1377)
                     /locus_tag="LP245_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519444.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1343..2674)
                     /locus_tag="LP245_001521"
     CDS             complement(1343..2674)
                     /locus_tag="LP245_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBL1519445.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2930..3496
                     /locus_tag="LP245_001522"
     CDS             2930..3496
                     /locus_tag="LP245_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1519446.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3641..3728
                     /locus_tag="LP245_001523"
     tRNA            3641..3728
                     /locus_tag="LP245_001523"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3673..3675,aa:Ser,seq:cga)
     gene            4062..5036
                     /gene="bsh"
                     /locus_tag="LP245_001524"
     CDS             4062..5036
                     /gene="bsh"
                     /locus_tag="LP245_001524"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBL1519447.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            5361..7256
                     /gene="asnB"
                     /locus_tag="LP245_001525"
     CDS             5361..7256
                     /gene="asnB"
                     /locus_tag="LP245_001525"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBL1519448.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEKWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(7451..7897)
                     /locus_tag="LP245_001526"
     CDS             complement(7451..7897)
                     /locus_tag="LP245_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBL1519449.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8125..8274
                     /gene="rpmG"
                     /locus_tag="LP245_001527"
     CDS             8125..8274
                     /gene="rpmG"
                     /locus_tag="LP245_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL1519450.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            8362..8880
                     /locus_tag="LP245_001528"
     CDS             8362..8880
                     /locus_tag="LP245_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1519451.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(8957..9913)
                     /locus_tag="LP245_001529"
     CDS             complement(8957..9913)
                     /locus_tag="LP245_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1519452.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10079..10885
                     /locus_tag="LP245_001530"
     CDS             10079..10885
                     /locus_tag="LP245_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519453.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            10882..11871
                     /locus_tag="LP245_001531"
     CDS             10882..11871
                     /locus_tag="LP245_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL1519454.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            11868..12872
                     /locus_tag="LP245_001532"
     CDS             11868..12872
                     /locus_tag="LP245_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL1519455.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13004..13546
                     /locus_tag="LP245_001533"
     CDS             13004..13546
                     /locus_tag="LP245_001533"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBL1519456.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            13566..14264
                     /locus_tag="LP245_001534"
     CDS             13566..14264
                     /locus_tag="LP245_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBL1519457.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            14285..14497
                     /locus_tag="LP245_001535"
     CDS             14285..14497
                     /locus_tag="LP245_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBL1519458.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            14497..15459
                     /locus_tag="LP245_001536"
     CDS             14497..15459
                     /locus_tag="LP245_001536"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBL1519459.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            15477..15872
                     /locus_tag="LP245_001537"
     CDS             15477..15872
                     /locus_tag="LP245_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL1519460.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16035..16400
                     /locus_tag="LP245_001538"
     CDS             16035..16400
                     /locus_tag="LP245_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBL1519461.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            16397..18208
                     /locus_tag="LP245_001539"
     CDS             16397..18208
                     /locus_tag="LP245_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBL1519462.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTNENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(18270..18437)
                     /locus_tag="LP245_001540"
     CDS             complement(18270..18437)
                     /locus_tag="LP245_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBL1519463.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            18685..19674
                     /gene="galE"
                     /locus_tag="LP245_001541"
     CDS             18685..19674
                     /gene="galE"
                     /locus_tag="LP245_001541"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBL1519464.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            19686..21170
                     /gene="galT"
                     /locus_tag="LP245_001542"
     CDS             19686..21170
                     /gene="galT"
                     /locus_tag="LP245_001542"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBL1519465.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            21194..22174
                     /locus_tag="LP245_001543"
     CDS             21194..22174
                     /locus_tag="LP245_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1519466.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            22365..23087
                     /gene="tsaB"
                     /locus_tag="LP245_001544"
     CDS             22365..23087
                     /gene="tsaB"
                     /locus_tag="LP245_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBL1519467.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            23071..23613
                     /gene="rimI"
                     /locus_tag="LP245_001545"
     CDS             23071..23613
                     /gene="rimI"
                     /locus_tag="LP245_001545"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBL1519468.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            23620..24084
                     /gene="rimI"
                     /locus_tag="LP245_001546"
     CDS             23620..24084
                     /gene="rimI"
                     /locus_tag="LP245_001546"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBL1519469.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            24081..25097
                     /gene="tsaD"
                     /locus_tag="LP245_001547"
     CDS             24081..25097
                     /gene="tsaD"
                     /locus_tag="LP245_001547"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBL1519470.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(25706..26407)
                     /locus_tag="LP245_001548"
     CDS             complement(25706..26407)
                     /locus_tag="LP245_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL1519471.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            26868..28097
                     /gene="arcA"
                     /locus_tag="LP245_001549"
     CDS             26868..28097
                     /gene="arcA"
                     /locus_tag="LP245_001549"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBL1519472.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            28188..29207
                     /gene="argF"
                     /locus_tag="LP245_001550"
     CDS             28188..29207
                     /gene="argF"
                     /locus_tag="LP245_001550"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBL1519473.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            29322..30269
                     /gene="arcC"
                     /locus_tag="LP245_001551"
     CDS             29322..30269
                     /gene="arcC"
                     /locus_tag="LP245_001551"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBL1519474.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
BASE COUNT         9919 a         5198 c         6318 g         8915 t
ORIGIN      
        1 taaaaaaagc gttagcaact atgcttaaaa agcatatcga ctgaataaac taagcattgg
       61 acaggctgaa agactacatt taaaatgaaa tgcgaagaaa caatagaaaa taaagttgcc
      121 ttagaaccat agttgaatca cctaacagtc gtgaagggag aataagagaa atggcagaaa
      181 aacaaaccgc aggacgagat caattaggag attttgcacc aaaatttgca gaattgaatg
      241 atgatgtttt atttggacaa gtatggtcca gagaagaatt atctgctcat cagcgtagta
      301 tcatcaccat atctgcatta atttcaggag gaaattttga acaattgcca gctcatctga
      361 agattggcaa gcaaaatggc attactagtg aagaaatagc agaaatcatt acccatttag
      421 ctttttatgt aggatggcca aaagcttggt cagcttttag tttagcaaaa gaaatctatt
      481 tagaagaaaa tagcgaagat aagaaagagg cgtaaatgac gacaaaacac gaagaaatac
      541 acaatggcgt gatttttcca gcaggtgaaa aaaacgaagc ttacgctcaa gtatttaccg
      601 ggtaaagcta tctgaatatg ttagtgaatg atcccgaagt ttctgttggt gtaggtaatg
      661 taacttttga accaggttgt cgcaatcact ggcatgtcca taaagacggc tatcaaatct
      721 tacttgtgac cggaggagaa ggctggtatc aggaagaagg aaagccagca agacgattaa
      781 tggctggaga tgtcgtcgta acgcacaaag ggattaaaca ttggcatggt gcgacaaaag
      841 acagttggtt tgaacatttg gcgatcactg ctggtaattc agagttttta gaacctgtaa
      901 cagatgaagt gtatgaagga ttggaaaatc aataatgtca agcttgaaca gctcctgaaa
      961 gtagatttta atcgaacttt caggagctgc ttttttgatt cagtctttta taaatagaaa
     1021 atagggttaa taataggaat gagaagcacg tcgaaagatc ttaatattga taatcggctg
     1081 ggcatacatg atttccacgt catcaatcaa actacctaac agatgataat cttcccgatc
     1141 atgtcgggga ttacctaata gttcttgata atagatttcc atactagggt cccgaggatt
     1201 gttcagcaaa tcagcaagta catctaaatc ttctggctga gtttctgccg taccctgtat
     1261 ctctatgaaa agcccttcct cagcaaattc tactccaata cgtatttcag ttatttcatg
     1321 ggaatataaa taagtaagaa gctcatcgat gattcttttt gataattctt tttccaagtg
     1381 tctttttttc ctttctgaca gcggtaaagt tatctagtat cggtacaagg atacctgcaa
     1441 cgaaaccagt tgaaaaacca ctgttatata gatttagtcc tccgtgcaaa gtgctgacgt
     1501 tatggacaag agcaatatgt agtacaccag ctattacacc gtaaaaactg ccgtaaaaac
     1561 cgcttatggg cgcgagacct gtcccaaaca cagctgcaac aagcatgcca gtactggtga
     1621 tctcatgaaa agttccaaac aaagaagcaa taaatattcc gactagtatc ggaaaactgt
     1681 tttttaaatg acaaccaaaa gcactgaaac ccaccgcaga taaaatagca ccgatgacag
     1741 gtccatttaa ctgaccgcca accagcaaaa cataagaaga cagcatcaga ccaactaagc
     1801 ctatgttgat caaagtagca ccaataccag aattagcaat gaaatcagtt gtcaattttc
     1861 cagatgaatc gaaaatttct cgaatcccca aaagccgaaa ggaattataa tagaaaccaa
     1921 ttccgactgt cagcgaaaaa aagccaaaaa taatccaaat gagaggaaag tgatattcat
     1981 tgaaaaccaa tgtattttcg acgattgaat agctgaataa cctcaaaaca gcagtaaaag
     2041 tcatcgcaat caacccagag gtgaatccaa tattataaag tgtgaatcca cgatggaaaa
     2101 ctaaagtttg agcagctaag ggcggaagaa gtagaccaat tgctatgcca gctaaattcc
     2161 ccaataaaat acctatcagt aaaggaaaac gcataccaaa agtgatataa ctaacgaccg
     2221 gtgataatgc gctaccaaac agtccgatca tgatgtactg agaaaaaggt ttattgacaa
     2281 atacagcgta tagatacaca cctaaaatga ttgagataga attataaagg tttttgccaa
     2341 aaaaagagaa accggtaact gttagaatcg aagcaaataa gggaccgttt aaaatcacct
     2401 tgtgccgata agctaaaagc acagaaagta aggtcaaaat ccctacattt atgaatgcgc
     2461 ttccgaaacc gcctaaagca aaataatctg tcaaaagatt gcttggcgag gtaagaatag
     2521 ttagcaatcc actccaatta tcagtaggag tattagaaag caagccaata aaaagaaaaa
     2581 aaacacctgt aaaaccaaga taaaaatact ttcttttctg tgaaacgatt cgtttttgag
     2641 gatgaatata aataacgtca gtttcgtttt ccattacaca ccttcttttt cattttcttt
     2701 aactataact tgaaatgaaa gatttggaca actatcattt aggtcaaaac taaaaatgta
     2761 agggaaccca ttgaatttaa ccaaattttt ttaattttgc aaaaaaaagt taaagaagac
     2821 tgaaaaaaaa tttaaaatat aacgttttga gtaaaatgtt tgcaaaaaat gctaaaaata
     2881 gggtacaata aaacaacata tactgcagta aagaagtggg ggagttttaa tgagaagaaa
     2941 agtctatacc aaggatcaaa ttctaaaagc tgcttatgat gttgttgcaa aggaagggtt
     3001 taaaggattt actgcgagaa atattgctaa aaagatgggg atttcgacac agccgattta
     3061 tctggaattc aaaaacatgg aagatttaaa aaatacgttg ctggattcta tctttgaaca
     3121 actaaaagaa gatgttttcc ctattgaacg tactggtgat aaaatcattg atctcggttt
     3181 gaactatatc tactttgcaa aaaagcatca tagtctttac atggcattgt acattgatga
     3241 acatggggac ggaaagaaaa tgcatgattt ttcatacaat tatttccgtg aaatagttaa
     3301 agaagatgaa agatacaatc aattatcgga tgaatatgtc gatgctctgc atactggtac
     3361 atgggtagca gtgactggct tagcgtcatt gatgtcatca aacatcatgc atccaacaga
     3421 agaacaaatc attgcactga tcaaacggac aattgactcg attttagcat tagataatcc
     3481 tgaaataatc agatagtgtt ctatcagtat gaatttgatc ggtaagtccg ttggctgcaa
     3541 actgtcaatg gacttttttg ctaaaaaaag cgatttctgt tatttatcta ttagaaatag
     3601 gcttgacatt tcgtgaaaaa agtttaaaaa tagtacttac ggaaggttgg cagagtggta
     3661 atgcaccgga ctcgaaatcc ggcgaaccgg ctaataccgg cgcgcaggtt caaatcctgt
     3721 accttcctta tatcaacgat tagaggttgt gaagaagctg tcctgcatca agtaataaga
     3781 acggccaaac aaaaatagct tttcctattt tttcgtttga ttgggcttat taccgcagat
     3841 gcaagctttt gaacaccgtt tgttcggaat aaggggctgt gacaagactt ttgtcacagc
     3901 cccttattgt tgtactttta acctacaata ttttttgatt ccccctgagt actatttttt
     3961 ataaatgcta gtaaatcaat cttctttggc ctttttttga taaaaaaaat actagatgta
     4021 agataaaagt gtaaaaacga tttgttttag gacgggaaac gatgtgtacc gcaatcactt
     4081 atgcaacgaa agaccattat tttggaagga attttgatta tgagatgtct tataatgaag
     4141 tggtcactat tactccaaga aattatcgtt tcgattttag aaaggtaaaa aatttagata
     4201 aacattatgc aatgatagga atagcagctg gggtatccaa ctatccactc tattatgagg
     4261 ctacaaatga aaaagggttg agtatggcag gactgaattt tcctggcaat gctgattata
     4321 aagaattaca agaaggaaaa gataacgttg caccatttga gtttattcca tggatactag
     4381 ggcaatgctc aaccatagac gaagctaaag aattattggc tactatcaat ctagtcaata
     4441 tcgattttag tgaaaaacta cccttgtcac ctttacactg gttattagct gataaagaaa
     4501 aatcgatagt aattgaaagt atgaaagatg gacttcattt atatgataat cctgtcggtg
     4561 tgttgacaaa taatccgcca tttgattatc aattatttaa tctgaacaat tatcgctcgc
     4621 tatcaaatgg aacaccagaa aatcattttt caaaccagat cagcttgaat gtttatagtc
     4681 gtgggatggg aggattgggc ttacctggag atctctcttc tgtttctcga tttgtaaaag
     4741 ccacatttac taaaatgaat gctgcatcag gtgattcaga atctgaaagt atcagtcaat
     4801 tttttcatat actaggctca gtcgagcaac aaaaaggagt atgcgatact ggagaaagaa
     4861 aatacgaata tacgatttat tcttcttgct gtaacgttga taaagggatt tattattatc
     4921 gtacgtatga agacagtcaa attactgctg taaatatgaa taaagaagac ttggatcgtc
     4981 atgaattggt cagttatcca gtcataaaag agcaacagat aaactatgtc aattaattaa
     5041 tgaatagatc cgtttggtat catattttct gatacagtca taattagaca cgatctttag
     5101 gtcgtgtctt tttttgctgg tttttttgga aatagcatcc actaatattt ttttaacacg
     5161 aagagaataa ggtagcctca aaaaagaaaa catggtaaat tagatattgg gactttattt
     5221 tctgtaaaaa cagaaacttt catcttttgt tttcacgtga cgaaattgta agagagaaaa
     5281 tattcgtccg ctatttattc tatgataaga tgcatatgaa tgaaataaac agtaatttta
     5341 tattaggatg tgaaagttaa atgtgcggta ttgtaggttt tgttaacgac aaggacaaca
     5401 aaaaaacaat tattaataca atgatggatc gaatcgttca ccgtggacct aatagttcag
     5461 gagaatatat cgataaacat gttgctttag gattcagaag attaagtatt attgacttag
     5521 agggcggtac tcagcctatt tacaatgaag atcggacaaa gatcattatt tttaatggcg
     5581 aaatctataa ttaccagcct ttgagagaag aattgattgc agctggccac gtttttcaaa
     5641 cacatgcaga tacagaagtc cttttgcatg gttacgaaga atggggaaca gaattattgc
     5701 aaaagatccg cggaatgttt gcttttgcta tttgggataa tgaaaagaat gagttattcg
     5761 gtgcaagaga ccactttggg atcaaaccat attattatgc agaaatgaac ggaacattta
     5821 tgtttggttc agaaatcaaa agttttctgc ctcatcctga ttttaacaaa gaattgaaca
     5881 aagaagcgtt gaaaccttat atgactttcc aatattctcc attaaacggc gaaacattct
     5941 tcaaagatgt ctatcgtttg cctgaaggcc attattatac gtataaagat ggaaaaatag
     6001 acattcagca atattgggat gcagattttg aaacaaaaga aacgcattcc cgacaagaat
     6061 ggatcgaaaa aatcgacgaa accgttcaag cttctattga agcacatacg gtcagtgatg
     6121 tagaagttgg ttctttctta tccagcgggg ttgattccag ttatgtaacc tctgtattga
     6181 aaccagatca ttctttctca atcgggtttg atgataaaac ctataatgaa gcgattgaag
     6241 ccagaaaact aaccgaacta ttggacttag ataatacagc agcagtgatc gacggagaca
     6301 tgtcgttcaa agcattccct ttgatccagt atcacttaga tgaacctgat tcaaatcctt
     6361 cttgcgtacc tttgtacttt ttagcaaatc ttgcttcaca aagtgtgcgg gtagtccaat
     6421 ctggagaagg ggcggatgaa ctgtttgcgg gataccaaac gtatggattc catacgaatt
     6481 caaaattcat ccgtgtgatt gctcaaggat tgaaaaaatt accaaaagga acacgctata
     6541 atttaggacg taaaatcgga aaaatgaaaa atttccatgg acggatccat ttatatgaat
     6601 cacttgctcc tgcaaaagaa tattttatcg gtcatgctcg agtgttcgaa gaatcagaag
     6661 catcagaagt gttaacacca aaatatcaaa cagcaccatc tgtggatgaa atcatgactg
     6721 ttcattacga gaaaacagaa ggaatcaaag atgaagtcaa taagatgcaa tatgtcgatc
     6781 ttcatcaatg gatgccaaaa gatatcttgt taaaggcaga taaactttct atggcaagtt
     6841 ctttggaagt ccgagtacct ttattggata tcgaagtcat gaaattggct caacaaatac
     6901 caagtaagtt tttattgaat caaaacaaca caaaagatat tttcagacaa gctgcgaaca
     6961 aacatcttcc ggaaaaatgg tcgaatcgtg tgaaattagg attccctgtg ccaatcaaag
     7021 cttggttgaa agaagaacac ggctacgaac aagtcaaagc attgttcgaa gcagattttg
     7081 caaaagaatt ttttgatcaa gaaaaaatca tgaagttgct agatgaccat cacgaaggac
     7141 gtaaagaaga gcaaagaaaa atctggacaa tcttcagttt cttgacatgg tataaagtct
     7201 actttgtaga tgaaacgatt ccgcaagcag aagcaatcga ctatgtgact gtttgatgaa
     7261 aatcaaatat caataaaaaa gaggttttct cctaccgttt aacactgagt gataagaaac
     7321 aatttcaaaa aacagctctt cccgttttat agatattatg acttatggtt cggagttggc
     7381 agaggaacac cattgtttcg aacataaggg ggttgtgaca cgattttcgt cacaacccct
     7441 ttacatatgt tcaataatcg atttcttttt cttttgtccc atctttttta taaatgaaca
     7501 aagttgattc tttgttttgt gctacttgct ttcctttttc gattgcttct ttttttgtat
     7561 caaaatggtt gcttgccttt tttgcccctt tagatttcac gatccattgt tcttcctcat
     7621 attctacgat cacatctgaa tcaagcagtt ttccagcacg aggattcgta tcgtgttcat
     7681 ccgtcttgct tggatttttt tctttttcga aagttcgttt ttctgattca ctagcatctt
     7741 cataccattt ttttgcttga tcaatggcaa ttgggatcgc acggttatca gggtaccctt
     7801 catctaataa tgcatttgcg atgtcgattg ctttttttct tgtcaattta tctaagtttt
     7861 tcattgatgc aggaaagtcc ttcatgttcc atggcatatt agtatccccc tttattaaaa
     7921 aacataatct atataaacaa gtgtaagggt atttatacaa aaagaaaaag attttgtttg
     7981 agaagtaaaa ccgttgtatt tatcgtcaag tagttttact taacaaaatc gtgaaaaaca
     8041 ctagcaatct agaaaaaatc atggtaagat aatcaagtct gagagtcatc ttagaggatt
     8101 cttgtaaaaa tgggagggaa aaacatgcgc gtaaacatca ctttagagtg tacttcttgt
     8161 aaagaacgta actatctaac aagcaaaaac aaacgtaaca atcctgatcg tttggaaaaa
     8221 caaaaatatt gcccacgcga acgcaaagtt actttgcacc gtgaaacaaa ataatgtttt
     8281 taaagttctc aattccttgc tggtcaaaga attgagactt tttttatctc aaaacatcta
     8341 aaatcataag gagcggataa tatgtttatt tccatgtggg cacaagataa aaatggtctg
     8401 atcggcaaaa atggtttgtt accatggcga ttgccaaatg atatgcgttt ctttcgcgaa
     8461 catacaatgg atcgaatttt agtgatggga agaaagacct atgaaggaat gggggatctt
     8521 tcacttcctt atcgccatat catcgtgttg acaacgcagc caaattttcg cacgaaagaa
     8581 aatgcggaag taatgcattc gatcgatgaa cttttgtcgt atagtcaaac gatctcagaa
     8641 gatatctatg tttcgggtgg tagtcggatt tttcaagaac ttcttcctta cactggtcgg
     8701 atctggcgaa cattgatcga tagcacgttt gaaggcgata cgtatattgg gaatattgat
     8761 ttttcagact tcgcccttat agaggagtat gaggggataa cggatcaaga aaatctatat
     8821 gcccatcgtt ttcaaaaatg ggaaagagta aaaaataggg ttgcttcaaa agaagaataa
     8881 aatctatgcg tctagtttgt taataagaaa aaaagcatat cacgactaat cgtgaagatg
     8941 ctttttttag ttaaaatcaa tttagttttt ctttgatatc attgaccatt tcctgactgg
     9001 caataggtcc gttatatagc caactagatt caggtccgaa ttgcagtaca tgattgtctg
     9061 tcactgcttt aagattcttc cagcttggtt cattgaacat ggcagcatct ttgtcactgt
     9121 tcacaaggat gatgtagtca gcatctaatt cagctagctt ttcagaggaa acagcagacc
     9181 agtcagaagt ggcttttttg gagacctctt ccactagatc aggaacacca aattccagat
     9241 cgtcgtatac gattcttcca cttgaccgat ttttgctgac cataaaggct gagttgttgg
     9301 tcacccacaa cactgcagct gtcttgttct cgattttatc tgctagttct tctcgagttt
     9361 tcttgatgga tttttgataa tcggaaatga tcttttctgc ctctttttct tttgccaaag
     9421 ctttgccgac atcttttagt tgttcttccc atgtgacatc tgttccgttt tttacaacat
     9481 aagttggcgc gattttgcta tattgttcgt atttcccgcc ttcgacagta gcggaagaag
     9541 aaatcaacag caaatcaggc tcaaagctta acactttctc ataaggaagg tcataagaaa
     9601 tcgttgggac atcctttaaa tcatcttgca gataatcttg aatggaacca ctgccaacag
     9661 tccactgggc gataggtttt tcccctagtg caatcagata gtcttctaag taactgccga
     9721 tgatccgttt gggcgcgttt ggaatctcta ctttatgtcc aagtgtatct gtgactgtat
     9781 gagtactatt ggatgaagtc gtcgaattgg cagttgtagc tgtttcttta tctgaagagg
     9841 gggagcaagc gctcagtact ccagccagca gcaatatgct agataatgtg aatacttttg
     9901 tttttaattt catttctttc ctcctaacat aattgagaat ctttctcatt ggttattatt
     9961 cctgatattt cgaacgctgt caaccgcttc atttggctat agatatgaaa gtagcgcttg
    10021 acgaaatgtt gaaacagcgt cataattgag aatgattttc agcgaaagga tgggtgaaat
    10081 gacgagatta agagcagctg acattgcagc cggctacgaa aacaaaaaaa tcattgaaaa
    10141 catgtctgtt acgattcctg aagggaaaat cactagtttg attgggccaa atggaagtgg
    10201 aaaatctact ttattgaaaa gttttacccg tatactacct gtgaaatcag gaaagatcat
    10261 tgtcaataac tctgatatct ctacatacag ttcaaaagaa cttgcaaaaa aaattgcatt
    10321 attagcacaa actagtgaac accctacagg tatgacagta gaagaagtag tatcttacgg
    10381 acgataccct tatcaaaaac tgttcagtgg catggacacg caagatcatg aagcaatcga
    10441 gtgggcgttg gatgctacag gtctagctgg atttcgtatg cgggatatcg caacgctgtc
    10501 tggtggacaa acccagcgtg tctggatcgc tatggcgctt gctcaggaaa cagatatctt
    10561 gatcttggat gaaccgacaa catttttaga tccggcacac caattagaga tcctacagtt
    10621 attgactgaa atcaatcaaa tgaaacaaac aacgatcttg atgtcgattc atgacattaa
    10681 tcatgcttca cgtttttcag attatttatt agcaatgaaa aacggtaagt tgatcacaga
    10741 aggtacacct gaagaagtga tcacaaaaga gtgtatgaaa aaaatatttg agattgatgc
    10801 aacgattgtc acgcttccaa gaacaaataa accagttttt ctaacctatg atttgttgcc
    10861 aaaagagcag gaggatcaat tatgaggact atgaagaaaa atagactcct gcttttggtc
    10921 tgttttgttc ttttgattat tttttttgtt gctctttcaa atggcgcagc gactgtggga
    10981 aaagcagatt tttggcaggc gttgtttgat tttgatagat caaaacaaag tcaccaaatc
    11041 atacgaaata ttcgtttgcc tcgtgtggcg ggagcatttc ttgtagggag ttgttttgca
    11101 ttgagcggtg cattgatgca aggagtgaca agaaatcctt tagcagattc aggcttacta
    11161 ggaatcaacg cgggtgcttc gttggcaatg gcccttagtt ttgctttttg gcctaaagct
    11221 tctgattttt ctgtgtttct aatgtcattg gcaggttctt ttgctgtaac tttgctcgta
    11281 tttggttttt tgcagttttc gaaaatgggc atgaatcctt tacagctgat tttagctggc
    11341 gtagctatta gttctttttt tactgctatc agccaagcac ttacccaatt ctttaatctg
    11401 cagcaggatc ttgctttttg gtttgtaggc ggagctgcca atatcacatg gaaacaatta
    11461 gcagtattgt ttcctttata tatacttgct gttttggttt ctttttcatt aggaaaagca
    11521 atatctttga ttcatttgag tgaaacacat gcattagctc ttggaagtca tcctaaacga
    11581 acgcggttga ttgttttctg tctagttgca gtgttagcag ccattgccgt ttcgttagtc
    11641 ggacctgttt catttattgg gctgttggtt ccgccagttg ttcgcggaat ggttggaacg
    11701 gactatcgtt atgttctacc tgtctctttt ttagttggcg gtggattggt tatgttggcg
    11761 gattttacag cgaggatgat caatccccct tttgaaacac cttttggatt agtcattgca
    11821 ttgattggcg ttccgttttt actgatacaa gtaaggaggg aacaacggtg aaaaaaatat
    11881 attggacgtt ctatttcttg ctttttgtac ttgtcatcct gtctataggt agtttaatga
    11941 ttggtacgcc ttttatttac ctggatcagc tttttgccac gttcataggg aaagaatcat
    12001 cttctttggc gctgattgtt agagaatttc gagttcctcg attactgatc agtttattag
    12061 caggagcttg tcttggcgtt tctggttata tcttgcaagg agtaacaaga aatgaattgg
    12121 cagattctag tatattgggc attaatgccg gagcaggatt tttagtgatg ctttatttag
    12181 gtttcttttc gcactattcg ctgccgtttc tattgctagt tgtagccttt ctaggtggtg
    12241 ttttagctgc ttgctgtgtc tatcttgcgg cctatgatcg aaatggcttt ttgggtatga
    12301 atcgaatctt attgtccggt attgccgtta atgccggcct ttctgcatta acattgctat
    12361 gcacgatcca attatctaag gaaaattatg gatttgtgaa tgcatggtta gcgggatcaa
    12421 tctggggtgc gagctggcct tatgtttggg cattgcttcc atgggcggtt atcttaattc
    12481 cgctaggagg actttatgca cagaggattg tattgctatc atttggtcaa gaacgcgcgc
    12541 aaggattagg ccttaacgtg gctaaaagtc aaaaaatcct tttgttgtta gctgttgctt
    12601 tggcaagcgg tagtgtagcg gtgacaggta gtttatcttt tgtaggacta ctagctcctc
    12661 atgctgcgaa gctagtcgta cgtaaagaaa ataactggac ctttgttctg agcggtttgt
    12721 tcggttccat ttttctgctt agtgcagata tggttgctag agtgattcta ctaagtgggg
    12781 aagtacctac aggaattttg attgcccttt ttggtgcgcc atattttctg tatgcacttt
    12841 ttatcagaca aaaacacgcg ctgaacagtt gaaattcatt aaaaaaggaa ggccaatcat
    12901 ttctaggtct tctttttatt ctatttatgc atttatttga aagttcgatt gctatttttc
    12961 tttttttcct ataccatttt atgagagaag gaagggtgag tttttggacc aattgaaagt
    13021 aagattacgc cggaaaggaa tcgaaaagct gaaaaatctg gccaaaagtg gcaagaaaaa
    13081 ggaaaaagaa cagcgaatct ataaacagct attcgccagc gagtactgga agtcagcaaa
    13141 agtgataggg acgactttat cgaatgaatt tgaactggat acacagccgg ttatccaacg
    13201 agcagaaaaa gaacaaaaga aaatagttgt acctaaaact ttgccgaaac gtcagatggc
    13261 gttttatgaa atggatgaac agtccgttct tgtacgttcg agttttggtg ttcttgagcc
    13321 acaatcagag aagctctatt tgccggagat gatcgatctc ctcattgtac caggtattat
    13381 ctacaataga gccggttatc gaatcggttt tggcggtggt tattacgacc ggtatttaaa
    13441 taattttcat aaaaaaacat gtagccttgt ttttcgtgaa caattgaatg aacaatggca
    13501 accggagagc tttgatcaga agatccaaca attgtttatt gactaaaatg aaatgggagg
    13561 ttttcatgaa ttatcaacag caaataaaat tgcgtgcatg gttaagacga ccgttatgga
    13621 cctatgcttt tttagggata cagacagcgg tcttcctcat gatggaatta tttccgcgac
    13681 ttgagatccc ttattatgcc ggaatgtatg gtccttatct tgttcacttc aatgaatggt
    13741 ggcgtttagt gacaccaatc ttcatccatt ttggactgat gcatttcgta atgaactcac
    13801 tgatactgta ttttatgggg cagcaaatcg aggcaatcta tggccattgg cgttttttct
    13861 tgatttatat gttcagcggg ataatgggaa atacagcaag ctttgctttt aacgaagcga
    13921 atgttctgtc tggtggtgca agtacttcga tattcggttt gttcggtgcg ttgtttatct
    13981 tagggtttca ttttaaacat aacccagcga tccagcagct agtcagacat tttcttttat
    14041 ttattgtgtt gacatttgtt tttggtcttc tggatacctc tgtagatgtt tggggacatg
    14101 tcggtgggct aattggcgga ttagtgttag ggaatgtttt gggtctaccg aaacaacaga
    14161 caagctattc gatacaccaa aggattcttt ctacactagt ttttgtattt ctttttgtaa
    14221 tatgtatttt actgggttta aaaaaatatg gtttacttgt ataatatgaa ggaagtgctt
    14281 aaagatggag agcttatatg atgtacagca gctgttcaaa aaatttggca tctttatcta
    14341 tgtgggtgca cgcatctatg acattgaatt aatgactatc gaattgcgta atctgtatga
    14401 tagccgtttg attgatcatg atacatacat gacagcgtgg cgcatattaa aaagagagca
    14461 ccgaattgaa gaaagccgaa agaaaggaaa tttgtaatgg acaagaagat tattgggatt
    14521 gatttaggtg gaacaacagc aaaatttgca attttaacac cagaaggaga gattcagcaa
    14581 aaatggagca tcgataccaa tattttggat gatggtaagc atatcgttcc tgaaatcatt
    14641 gaatcaatca atcatcgttt gaatttatat aatatgaaag ccgaagactt tatcggaatc
    14701 ggcatgggta ccccaggaag cgtggacagc gaagctggaa cggttattgg tgcgtataac
    14761 ttaaactgga cagaagttca atttgtgaaa aaactgatcg aggcaggaac aggaatcaaa
    14821 ttcgctatcg ataatgacgc gaatgttgct gctttaggtg aacgatggaa aggtgctgga
    14881 gaaaacgatc cagacgttgt attcgttact ctaggaacag gtgttggcgg aggtatcgtt
    14941 gctggcggaa atttgattca cggcgtgagc ggagctggag gagaaatcgg acatatcact
    15001 gtggatcctg aagggttcga atgtacttgc ggtaaacgcg gatgtttaga aactgtatct
    15061 agcgctacag gtgtggtacg cctaggtcgt ttcttggcag aagaatacgc aggggattca
    15121 aaactgaaag caatgctaga caacggagaa gaagtaacaa gtaaagatat ctttgaaatg
    15181 gctcaagaag acgatccgtt tgcattgatg gttgttgatc gcgtatgctt ctacttaggt
    15241 ttagcttgcg gaaacttggg gaatacatta aatccgtcaa gtatcgtgtt aggtggagga
    15301 gtatcggcag caggagaatt tttacgtagc cgtgtagaga aatattttaa agaatttact
    15361 ttcccgcaag taagagaatc aacaaaaatc aaattagcag agcttggtaa tgaagctggt
    15421 gtcattggtg ctgcctcatt agccttgaaa tttgcttaaa aaaacggagg cattacatgg
    15481 ttttatgggt aattaatatc attttgctat tgattgtgct tgcaatcatc ctttgggaag
    15541 tctatctacg agtaatggcc aaacgttcag caacgacttt gacagaagaa gaatttcgag
    15601 aaggaatgag aaaagcacaa gtaatcgatg ttcgcgaaaa agatgtgttt gatgctgggc
    15661 atattttagg tgcaagaaac atcccttaca ctgttttgaa agattcatta ggatctattc
    15721 gaaaagacca gcctgtctat atttacgatc aaaagaaaag tttgagcatc cgtacagcaa
    15781 ataaattacg taaagcaggt tatcaagaga tttatttact taagggtgga tatgacggat
    15841 ggtctggaaa aatcaaaagt aaaaaagtat aaaacagatg attgtatgac agctttaaaa
    15901 accgaatcaa tcattagatt ttgaccaaga tcacatgaac ggcgcaatgg atagttgtgc
    15961 cgttcatttt ttttattttg tgctattatc tacatatata agctaagcga aaaggtagaa
    16021 agaaggaaac aactatgatc aaattaaaac gtgtttacct tgatgctgaa aaagaggatg
    16081 gctatagaat actcgtggat agattctggc cacgaggaat ttcaaaagaa aaagcgcagt
    16141 tagatctgtg gttgaaagaa attgcaccta gtaatgaagc acgcaaaact tttgaccatg
    16201 taccagaacg atttgcttca tttgcaaaga aataccagca agaattgatt ttcgaagaag
    16261 aaaagaagca agctattttt aaactcagtc aacttatgaa agaacatcca gtcattactt
    16321 ttgtttatgg tgcaaaaaat gaacatcaga accatgctgt tttattgaaa aaatttatcg
    16381 aaatggaggc atgcaaatga aaatagggat cattggtgcc ggacctagag gattaagtgt
    16441 agcagaaagg attctccata ataatcagga cagacattct cttgaacttt ttcttttcga
    16501 tcccaatggt cctggaggtc gagtttggcg gttgaatcag ccaccggagt tattaatgaa
    16561 ttctgtttct caacaagtga cgctttttac agatgaaaca ttgtccagtg gaggattggt
    16621 aacacaggga cccaacttgt ttcaatggag taaaggacct gctacagatt atatcgaaca
    16681 gacggtaacc aaaaataagc aactaattat agaagaaatc aatcgtctgg aaaaagatca
    16741 gcaatctact cgatgtttat acggactcta tcaacgctgg tttttctcaa agttgcaaga
    16801 agaatttcca gcttctattc agtttgttta ttctttagta aaaaaagtaa gcaaaagaaa
    16861 agatggttat cttttacaga cagatcagca aagctattct atcgatcagc ttgttttagc
    16921 aagcggtcac tgggaaaatg atgagacaga agaagaaaga gtgtgggtag actacgcaaa
    16981 gaaaaatgtt ttactgtatc agcttccttc taatcctgca gatgtagatc tttcgaagat
    17041 accgcctaaa gaaaatgtct ttttaagagg tctaggctta agtttttttg attatgtcgg
    17101 attgtttaca gtatcaagag gagggcgctt cgagaacgaa aagggaaaac tggtctatca
    17161 tccatcaggc aaggaaccga ttgtatacag tggatcaaga agggggctcc cttattaccc
    17221 tcgaggaaga aatcaaaagc aaggcggagc aatggcatgg ccacggttac taacaaatga
    17281 aaacctggag caatggcatc agtcgggatt tttgactggc gaaacatttt ttgactatct
    17341 gaaaaaagac gttgagttgt tttattacaa gaaaatcatc gaagaatatc acttgccgat
    17401 tccaaagaaa aattttgagc atgattttct ctccctctct tcagaggagt gtctcggaaa
    17461 gcatccagca ctaatccctt atagatggga ttggtcgtat ttagaaactc ctcttgccta
    17521 tcagaatgag cccttttcag aagctagccg aatatttatt gaagggcaga taaaagaagc
    17581 ggaaaaaggc aattgcacag gagcatttgc ttcaacattt gatgcattaa aagactggcg
    17641 tgatccaatc cggcaggcta ttgaatggca cgttttttct gctaaggaat acaaagaaat
    17701 actatgggga tggtttactc atctaaatag ctttttaacg atcggtccgc caatcattcg
    17761 gacgaaagaa ttagcagcac tgatagatgc gggtattttt catttgatcg aaccgccatt
    17821 tgatattcag caaaagcaca accgctatgt tatttctcta caagataaag aaatcagcag
    17881 tcgctatttg attgaagctc gattgccaca aacaagcttt tctcgttcaa gtaatcctgt
    17941 cataaaaaat ttgaaggaaa acaaacttgt tcgccctttt tcattttcag ataatacagg
    18001 aagttatcat tcagaagcta tagatgttga gcgaggtacg aatcgcgtga ttgatgcttc
    18061 aggggaaatc cagtctgact tttattgcta tggaatacct gttgaaggtg tggattggct
    18121 aactgcagca gtagctagac cttatacaga tccatggaat ctgagacagg cagataaaat
    18181 agcacaactt atattgactg acaaataaaa atacgcatga tgacttatct gttttttaga
    18241 aagtcttcat gcgtattttt aaataattat taacgagaaa cgcgtttacg cattgctttt
    18301 ttacggtttt cttcgatcat tgcttctttt tcgtcaattg gatcgatcac tgtttttttc
    18361 acagaagcaa ccaaaccagc aacggcagcg gctgttgcca gacttcctac taatattcca
    18421 gatacaaatt ttttcattga atccacctca tttattattt gttatatcta ttatggaaca
    18481 aaagagaaaa aaaggctagt tttacgtttg tttgtaaacc tttgcaaaaa atccttgaaa
    18541 atgtttacta aatgttttat tataaattta ccatatgaat ttacgaaatt ttactttgtt
    18601 tgttttcacc ataaaagtaa acttcgtttt ttaaattata tagaatcaac aaacacaatt
    18661 ttactaatca aaggagtgtt ttttatgaca attttagtac taggcggagc cggttatatc
    18721 ggttcgcacg ctgtagacca gctagttcaa aaggggtatc aagtagctgt ggtagataat
    18781 ttgctcacag gtcacaaaca agcagtacat ccagatgctc atttttatga aggagacatc
    18841 cgggataaag aatttctacg ttccgtattt gaaaaggaac cgattgaagg agtaatccat
    18901 tttgctgcaa gctctttagt tggagaatct gtcgaaaaac cattgatgta tttcaacaac
    18961 aacgtatacg gtatgcaaat cttacttgaa gtcatgcacg agttcaacgt gaataaaatc
    19021 gtattctctt ctactgcagc aacttatgga gagccgaaag agtctccaat cacagaagat
    19081 acaccagcta atcctaaaaa tccgtatggt gaaagtaaat tgatgatgga aaaaatgatg
    19141 aagtggtgtg accaagcata tggcatgcgc tatgtcgctt tgcgctactt caatgtagcc
    19201 ggagcaaaag cagatgcatc tatcggagaa gatcatacac cagaaacgca tcttgtccca
    19261 atcattttac aagtagctct tggtcaaaga aaagccttgg ctgtttatgg agacgattat
    19321 gatacaccag atggaacatg tatcagagat tatgttcaag tagaagattt gattgctgca
    19381 catattttag ctttggaata cttgaaagaa ggaaatgaaa gcaacttctt caatttaggc
    19441 agcagcaaag gatactcagt caaggaaatg ctagaagcag ctagagaagt gacaggaaaa
    19501 gaaattccag cagaaatagc accaagaaga gctggagatc ctagccgatt agtcgcttca
    19561 agtgaaaaag cgagagagat tctgggctgg aaacctgaat acacagatat caaagcgatt
    19621 atcaaaacag catgggattg gcatgtcagc catccaaatg gttatgaaga ataggggaat
    19681 gagatatgtc aatcagtcaa acgatttgtg attttgccac acttgcgatc gaagctggcg
    19741 gatggatgga aatggaccgc ttatatttac agaatcgtct tttagggatg gtaggagaag
    19801 atgctctaga aagcattgaa gtaagaccag ttaaggaaga atctgtagac ttattggatc
    19861 agcttgtcgc taaggcaaga gaaaatggtg ttctttcaga attgccagca gaacaagaga
    19921 tttttgaagc gcaattaatg gattttctca caccgccacc ttcagtcgtc aatgcattct
    19981 ttgcacagca ctattcgaaa agcccagagg aagcaactga gtatttcttt aatttaagta
    20041 agaaaaatga ctacatcaaa acaagagcca tcgcaaaaaa catcaaattt ccggcagagt
    20101 cggagtatgg tgaactggaa atcacaatca atttatctaa gccagaaaaa gatccaaaac
    20161 aaatcgcagc agaacgcgag gcggtaaaag tagactatcc tacctgcatg ctttgcatgg
    20221 aaaacgaagg atatagaggt cgcttgaact atccagcccg caccaatcac cggattattc
    20281 gaatgaatct agacggtgaa agctggggat tccaatattc cccttatgct tattacaatg
    20341 aacattcgat cattttatca gaacaacacc gcccgatgaa aatcacaaag gaaacatttg
    20401 ctagactgct tcggattact gaagtcttgc ctcattactt tgttggttcg aatgctgact
    20461 taccaattgt tggaggatcg attctttctc atgatcatta tcaggcagga cgtcatgaat
    20521 ttcctatggc aaaagcaccg atagaaaaac ttatcaaact agaagattat ccgcaagtca
    20581 tcgcaggagt cgtgaaatgg ccgatgtctg tgatccgttt gcaatcaaca gagaaaaact
    20641 tgcttattga agcagctaac tcagtattgg aaaaatggaa agcatattcg gatgaaacag
    20701 tatctatcag agctttttca gcagatggta caccacacca tacgattacg ccaattgcac
    20761 gaagaaggga caattacttt gagttggacc ttgtccttcg agacaacaat gtttcagaag
    20821 aacatcctga tgggattttt catccacata aagatgtcca acatatcaaa aaggagaaca
    20881 ttgggttgat cgaagtaatg gggcttgctg ttttaccacc tcgtttgaaa ccagaactag
    20941 tagaagtaga gcatttctta ttaggagaag aaaaccagat ggctgaatat catcgtccgt
    21001 gggcagaaca attaaaaaaa gaacatcctg atttgacgaa agatacggtc accgatgtcg
    21061 tacaaaaatc tgtaggtcag gtttttgcac gtgtactgga agacgctgga gtattcaagc
    21121 gagatgaaaa aggacaggca gcgtttgaac gatttactgc gattttataa acgtaaaaaa
    21181 ggaggagaga caaatggcaa caattaaaga cattgcgcag ttggcaggag tttctcctgc
    21241 tactgtttca agagttctca actatgatcc tgatctttcc gttggcttag ccacaaagca
    21301 aaaaattttt gaagcagcag aacgcttaaa ttatacgaaa catcgtaaaa atgcagcaaa
    21361 tactaagcaa acgcttcgcc tgatccagtg gtacgacgat acggaagagc ttgaagatct
    21421 ttattattta tctattcgcc taggaatcga aaaaaaggca gaagaagcaa acgttacttt
    21481 attgaaagaa acgtgggatt ccattagtga tcttccggca gatggaacga tcgcactagg
    21541 aaaattcgac gaagctcagt tattagaaat gaaaggatcc caaaatgcct tgcttttggt
    21601 agattctgac ggcacttctc aaggaatcga ctctctagtt gtcgacttta agtcaagtgt
    21661 tcaaaaagtc attgaacact ttgtctccca taaagcgcaa catatcgcta tgcttgctgg
    21721 aacagaatat acgaagaaaa accatcagcg gctaaaagat cccagaatta tggcatttca
    21781 acaagttttg gcagaaaaag gctacgacga aggtccaatt atcgaagcag atttttctgt
    21841 cgagtcagga tatcaagcag tgaagcagta tttaaaaacg aatccgcatg ttcctgatgc
    21901 gctttttgca gctaatgatg cattagcgat tggcgcactg aaagcgattc aagaaaaagg
    21961 tttagtggta ccagaagata tttctgtgat gggcttcaat gatgtcagtg tagcgaaata
    22021 tgtaacgccc tcgctttcta ctgtaaaagt ttataccgaa tggatgggag agctagcagt
    22081 ggagacgatt cttcaattaa gtaattccaa agcaccggtt tcaagaaaga ttattgtgga
    22141 aacagagttg attattcgag aatcaacgaa ataaaagatg gaaaagctgt gggaaaatgg
    22201 agtgataccg cagctttttt gtgtttcagg aaggggcaaa atttgcccgc cagcagataa
    22261 tcatgtatta ttgtactagt tttgcctttg gtattttcat cctcagaata aaaaagtatg
    22321 ctacaatgga aggcgagaat gtcatagcag aaaggatcaa atatatgatt acattaggaa
    22381 tagatactgc aaaccaaact ttggcgatcg gtgtggtaga agacgaacaa attcttggac
    22441 aaatacaaac aaatatcaaa cgcaaccaca gtgtaacact gatgcctgca atcgaccaat
    22501 tgtttgcaga tcttcaaata agtccaaaag acattgaccg aatcgcggtt tctgatggtc
    22561 ccggttctta tacagggctt cgtataggtg taacgacagc aaaaacgatt gcttatacat
    22621 tagataaaga gctagtagga gtatctagtc tgaaaaccat cgcggctaat tgcatcggtg
    22681 tggataatat tattgtgccc atgtttgatg ctcgaagaaa aaatgtatac gctggggcat
    22741 accgctggaa agaaaataga ttagaaactg tacttgaaga tgtacatatt tctgcttctg
    22801 atttgttcac acaactacaa aagctgaatg aagctattta tttcgtcggg agtgattgtc
    22861 acaaattctt ctctgaaata aaggaaatat tgcctagtgc gatgattaat acagttccag
    22921 catgggatat tccaagtggt gtaactgtgg ctcaattagg tgctttagtt gaaccagttg
    22981 cagagaaaca agcttttctt cctcgctatt taaaacgagt agaagcagaa gaaaaatggt
    23041 tggagacgca cacacctgga gacgaaagtt atgttgaaaa aatttagagc gtatgccaga
    23101 agcttttttc aagataaaat gatttataca gaaaaaacag tcgaacaaat cgatcgtcgt
    23161 tacgtactaa gagaattgac tacagaagat atcaaagagc tgctggatgt cgaacgagaa
    23221 gtctataatg gcgaattgcc atggacaaaa agtgccttta tatcagaatt gaagtcaccg
    23281 cttcctcatc tatatctagg tatctttgat aatggaagaa tgattggttt tatcggttca
    23341 agagcgttcg gtttagattg ccatatcacg aatattgccg ttcgaccggc atatcagcgt
    23401 aaacgaatcg gttcgctgct tattgacgaa atcgagaact ttgctataat gaatcgctgt
    23461 gagacgatgt cattagaagt gcgtatgagt aatcaagatg cacaaagact ttatcggaaa
    23521 ttggggtttc aagcaacaac gatcaaaaaa agatattaca ctgaaacaaa agaagatgcg
    23581 ttggatatga taaaactttt agaaaatgag tgagattagt tgatttgcag aaaaaaagat
    23641 tttgatgaag cgtacttggc agaatgcgta tggatgatta gcgaaaatgc ttatccacat
    23701 ggttcacctt ggacgaaaat gcagtttttg gcagacatcc aacagcctca ctctgattat
    23761 ctgcttttag ctgaagataa ccagatctgt ggctttattg gatactcgaa agtaatagat
    23821 gaagtcgaga tcacaaatat tgctgttgca gtttcagaac aaggaaaagg gcatgcacgg
    23881 catttgttac aattactgat tacggaacaa ataaaagatt cgctgcatgt ttttttagaa
    23941 gtacgtctat ctaatgaagc agcaagaaaa ctttatgaat cagaaaagtt tcgtatatta
    24001 ggtaaacgga aatcatatta tcgcaatccg acggaagatg cgatcattat gagcagaaag
    24061 ttaaaaacgg agacgatgaa atgaatgaag aattgattct ggcgattgaa tcaagttgtg
    24121 atgaaacgag tgtagcggtc gttagaaatg gaacagagat cttatctaac atcgttgctt
    24181 ctcaaataaa cagtcataaa cgttttggtg gcgtagtacc tgaagtagct agccgccatc
    24241 acgtagaaca aatcacctta tgcttggaag atgcactggt agaagctggt gtgtcggcag
    24301 aagatttatc ggcagtcgct gtcacttatg gaccaggact tgtcggctcg ttgctgattg
    24361 gtatttctgc agctaaggct tttgcttggg cacaccaatt gccgcttatt cctgtaaacc
    24421 atatggcagg gcatatctat gcagcccgtc tggttaaacc attccagttt ccattgatgg
    24481 cacttcttgt tagcggagga catacagaat tagtctatat gcaagaagat ggatcatatg
    24541 aaatcattgg ggagacaaga gatgacgcag caggagaagc ttatgacaaa gttggaagag
    24601 tattaggtct ttcttaccca agcggaaaag aaatcgatca gctagctcat cagggaaaag
    24661 ataattacca ttttccgcga gcgatgatcc atgaagataa ttatgatttc agttttagcg
    24721 gattaaaaag tgcatttatc aatttggtgc ataatgcaca acagcgtgga gaagatctag
    24781 acaaaaatga tttagcagct agctttcaag caagtgtgat cgatgtattg attactaaaa
    24841 cacttcgagc ttgtcaaaat tatccagtca agcaactgat tatagctgga ggtgtagcgg
    24901 ccaatcaagg gttgcgtgaa ggattgcagg atgctttggc aactaaactc cctgaggtag
    24961 aactagtgat tccccctctt cgactttgtg gagataatgc tgcaatgatt ggagcagcag
    25021 cacatgtgga aatgcaaaaa agaaattttg ctagctatca gttgaatgct gatccaagct
    25081 tggttttatc tgaataaaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
    25141 cccaggaaaa acggcttctc atgtttttga cctggctgtt cttattaccg cgtatgcaag
    25201 cttttgaacg ccgtttaatc aagagttcgt aagcctgtcg tttaactctg attcacaagg
    25261 aacaatttca aaaaacagct cctcatgttt atgaacatta tgacttgtga ccgaagagtt
    25321 gacaggtaca caccgtttaa tcgaaatagg gctgtgacac gtttttgtca aagccctatt
    25381 ttttacatac ttttaatcat tattgttatt ttgctatttt ttacagctta tttatcatta
    25441 tccgttcctc tgattgccct cactgagtaa tcgtttattg tcgaggaata tcgaataatc
    25501 tagatcggat gaggacaaga cgcttcatct agttaatcta acagtatttt ttgcaaacag
    25561 tgaatattac ataactgaaa cacacataga aaatctttga gtcttgtcca gtgatctaaa
    25621 actgccggat ctttcagaag ttttagggag gaaaataagc agtgaccctg atatttatca
    25681 gggtcactgc ttatttttgt tcgcgttatt ctctcatagc tggagtagta gctgtcttac
    25741 agaaagtaaa acgctttttg tcataatcta acagcccgga atcacgtagt tgtttgatta
    25801 cttgtccagc agtttcacgt gtcgtgccgc tattcactgc taattctttt aaggtgatcg
    25861 gataaggaat ggtgatatga ccatcttttg ttggtacgcc caattcttct ttcaaaatga
    25921 ataaattttg ttttacccgg tcaaaggcgc tagaggtcaa tccgatttgg atacgcaatt
    25981 catgtatttc aactacttta gaaatttttt gtatcatata gatcaactgt tcgggatttt
    26041 ttcgtgctaa tttttcatag taggaaacag gaaggtagaa tgtttcaata tcagtcatcg
    26101 cttgagctgt ataagtgtag gtctcttctc caaacattcc tgacatagga aaaaggttat
    26161 ttgtattcac atagtcatag tagtaataag ttgcactttc atcataacgt tctaaacgaa
    26221 cgagtccttt ggtcaagata tacaaccgtt gtctgggatc accatcgtcg aaaaggatct
    26281 gtcctttttt ataagaacga agaacagtat gttccttgat ctgttggaac tcttcatccg
    26341 agaaatgttc aaaatcaggt tgatatctga gttttgaaaa gtgaaaatcg attttattaa
    26401 cacgcattaa aaagtcctct ccttattgtt cactatattt attgtcactt tttttaaaga
    26461 atttgtaaag ttttaacata ccaacattag aaacaagttt taatacttta caaatataat
    26521 ttgttattat gtaaaaaata tacaatggta ttgaataatt tgttttgaag cgaatgattt
    26581 gtgtataaaa aacaacaata atacatatag taaacgctaa caacgataat ataatttatt
    26641 tttttaattt attcaaaaaa attttttcaa tgaataaata tttttttgaa agtgtataca
    26701 gaataaaaaa tgaataaatt acgcttaaaa atagaaaaac gtttaattat ttaattatcg
    26761 aatattaatg tgaggaatgt ctcattttga atgagacaaa attatgaaag tgattacaaa
    26821 aggaggatat cctatacatg taatcaaaaa gaaggaggca acacaacatg gataaaccta
    26881 ttcacgtttt ctctgaaata gggaaattaa agacagtttt actgaaacgg cctggacaag
    26941 aagtggaaaa tttgacacca gatattatgg atcgtctgtt gttcgatgat attccatatc
    27001 ttccgattgc tcaagaagaa catgacaact ttgcgaagac attgcaaaat gaaggcgtcg
    27061 agactcttta cttggaaaaa ttagcggcag aagcgattga cgcaggcaat gtcaaagaac
    27121 aattcttgaa taaaatgttg gatgaatctc atattgcatc gaatgctgta agagagggtc
    27181 ttcatgagtt ccttctatca atggaaacgc aagaaatggt agataaaatc atggctgggg
    27241 ttcgtacaaa agatatcgaa gtacgttcta gcagtctata tgatctgtca gcagacgatg
    27301 actatccatt ttacatggac ccaatgccaa acttgtactt tacacgcgac ccttccgcat
    27361 caatgggaaa tgggatgaca gtcaataaga tgacttttga agcacgtcgt cgtgaatcga
    27421 tgtttacaga atatattttg aaacatcatc caagatttgc aaataaagga atcgaagtat
    27481 ggttggatcg tgaaaatcca gatcatatcg aaggcggaga cgaattgatc ttaagcgata
    27541 aagtagtagc tgttgggatt tctcaacgaa ctaatgcgaa agctttagaa aaattagcac
    27601 gccacctatt cgcaaaaaat tcaggatttg aaaaagtgtt ggcaatcaaa attccgaaca
    27661 accgtgcaat gatgcatttg gataccgtat ttacaatggt agatcacgat aaattcacta
    27721 tccatccagc aattcaaagt aaagacggta agatggatgt ctttacaatc gaaccagatg
    27781 gtgatgatat caagattact cattcagata acttacacga aacgatgaaa gctgctcttg
    27841 gattagatga tcttgtactg atcccaactg gtaatggaga tgagatcgtt gcacctcgag
    27901 aacaatggaa tgatggatca aacacattgg caatcgctcc aggtgttgta gtcacttata
    27961 accgaaatta tgtatcgaac gaattgcttc gtagctatgg catcaaagtg ttagaaatca
    28021 attcaagtga attgtcacga ggtcgtggtg gtccacgctg catgagccaa ccacttgtcc
    28081 gtgaagactt gaagtaattt gtttcctgac ggcagtctta ctgtcagctg ccgtcgggat
    28141 ttcctcttta atcttaaata aaaacaatct aaaggagaat gtttaatatg aaagaatcag
    28201 tattccaagg aagaagctta ttagcagaaa aagactttac aaaagaagaa ttacaatatt
    28261 tgatcgattt ttcagaacac ttgaaagact tgaaaaaacg tggtatccca catcactatc
    28321 tagaaggaaa aaatattgcg cttttatttg aaaaaacatc tacacgtact cgttctgcat
    28381 ttactactgc agcgatcgat ctaggtgcac atcctgaata tctaggtgca aatgatatcc
    28441 aattaggtaa aaaagaatcc acagaagata cagctaaagt actaggacgt atgtttgacg
    28501 gaatcgaatt ccgtggattc agtcaaaaaa tggtagagga actagcagaa ttctctggtg
    28561 ttccagtttg gaatggcttg actgatgaat ggcatccaac acaaatgatc gctgactttt
    28621 taactatcca agaaaacttt ggaacagtag aaggtatcac tgttgcttac tgcggagatg
    28681 gtcgaaacaa tatggctaac tctttattag tcacaggtgc aattttagga gcgaatatgc
    28741 gtatcgttgc accaaaagaa ttacaacctg aagaagaaat cgtcaaaatg gcagaaggct
    28801 ttgctgaaaa atccggtgca caattgatga ttaccgacga tgttgataaa ggtgtagacg
    28861 gagcagacgt cctttattct gatgtatggg tatcaatggg tgaagaagat aaattcgaag
    28921 aacgtatcaa attgttgaaa ccttaccaaa tcaatatgga aatggtagaa aaaacacaca
    28981 acacagatcg tttgatcttc ttgcactgct tgccagcttt ccatgataca aacactgttt
    29041 acggtgaaca aatgaaagaa cgctttggca tcactgaaat ggaagtaaca gatgaagtct
    29101 tccgcagcaa atatgctcgt caatttgacc aagcagaaaa tcgtatgcac tcaatcaaag
    29161 cgatcatggc agcaacatta ggtaacttgt ttatccctcg cgtttaagca taaccacatt
    29221 catctcacga aaaaacgagt cagcattgag ggaaaatcac aaaacgctgg ctcgttttgt
    29281 tatctagaaa attcggtaga actgaagaaa ggacgaatga aatggccaaa cgaaaagtag
    29341 ttgtcgcttt agggggcaat gccatcttgt ctacggatgc aagtgcaaaa gcccaacaag
    29401 aagcgttaat ggaaacagca aagtatttag tgaaatttat cgaacaagga gatgaattga
    29461 tcatctccca cggaaatggt ccgcaagtcg gtaacctatt gattcagcag caagctgctg
    29521 attctgagaa aacaccggca atgcctttag atacatgtgt tgcaatgaca gaaggatcta
    29581 tcggttactg gttacaaaac gccatgggcg aagtactgaa ggaaaaaggg atcgataaag
    29641 atgtggtttc tttagtcact caagttattg tggatgaaaa tgatccttca ttcaaaaatc
    29701 caagtaaacc agtcggtcca ttctacacgg aagaagaagc caaagaacaa atgaatgctg
    29761 actccactgt gacattcaaa gaagatgctg gacgtggatg gagaaaagta gtcgcttccc
    29821 ctaaacccat ctcgattaaa gaagcacgtg tcatcgaaac gctggtcgat caaggagtta
    29881 tcacagtctc tgttggtggc ggtgggattc ctgttgtaga aacagctact ggattagaag
    29941 gacgagaagc cgtaatcgat aaagattttg cttcagaaaa attagccgaa atcatcgatg
    30001 cggatttgct gatcgtattg acaggagtag acaatgtgta tgtcaattac caaaaaccag
    30061 atcaaaagaa attagaaact gttactgttt cagaaatgaa acaatacatt gatgaaaagc
    30121 aattcgctcc aggaagcatg cttccgaaag tagaagcagc tattgcattt gttgaagcaa
    30181 aaccaaacgc taaggcaatc atcacttctt tagaaaatat cgagaatctt ttagcttctg
    30241 aagaaggaac gattatcgta gctgattaat ttgttaagtc tttcgtattt acgaaatgat
    30301 ttatagctat ccaggtggta tttcttctcc tttaggccat ctggattttt
//
LOCUS       DAFEEZ010000033        30231 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000033
VERSION     DAFEEZ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.033"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(138..302)
                     /locus_tag="LP245_001552"
     CDS             complement(138..302)
                     /locus_tag="LP245_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519475.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            597..1925
                     /locus_tag="LP245_001553"
     CDS             597..1925
                     /locus_tag="LP245_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBL1519476.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2127..2960
                     /locus_tag="LP245_001554"
     CDS             2127..2960
                     /locus_tag="LP245_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBL1519477.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2976..3713
                     /locus_tag="LP245_001555"
     CDS             2976..3713
                     /locus_tag="LP245_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBL1519478.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3868..4836)
                     /locus_tag="LP245_001556"
     CDS             complement(3868..4836)
                     /locus_tag="LP245_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBL1519479.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5068..5901
                     /locus_tag="LP245_001557"
     CDS             5068..5901
                     /locus_tag="LP245_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBL1519480.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5935..6774
                     /locus_tag="LP245_001558"
     CDS             5935..6774
                     /locus_tag="LP245_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1519481.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6800..7360
                     /locus_tag="LP245_001559"
     CDS             6800..7360
                     /locus_tag="LP245_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL1519482.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7559..9280
                     /locus_tag="LP245_001560"
     CDS             7559..9280
                     /locus_tag="LP245_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBL1519483.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9445..10587
                     /locus_tag="LP245_001561"
     CDS             9445..10587
                     /locus_tag="LP245_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL1519484.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10603..11814
                     /gene="thiI"
                     /locus_tag="LP245_001562"
     CDS             10603..11814
                     /gene="thiI"
                     /locus_tag="LP245_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBL1519485.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            12387..13034
                     /locus_tag="LP245_001563"
     CDS             12387..13034
                     /locus_tag="LP245_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBL1519486.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    13163..13379
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13427..16072
                     /locus_tag="LP245_001564"
     CDS             13427..16072
                     /locus_tag="LP245_001564"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBL1519487.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            16382..17695
                     /locus_tag="LP245_001565"
     CDS             16382..17695
                     /locus_tag="LP245_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBL1519488.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            17685..18338
                     /locus_tag="LP245_001566"
     CDS             17685..18338
                     /locus_tag="LP245_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL1519489.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            18393..19064
                     /gene="radC"
                     /locus_tag="LP245_001567"
     CDS             18393..19064
                     /gene="radC"
                     /locus_tag="LP245_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBL1519490.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGIYKLVHINYIRKFTVILPSGNTIMLSIIERHNAFFSS
                     SEDSL"
     gene            complement(18959..20311)
                     /locus_tag="LP245_001568"
     CDS             complement(18959..20311)
                     /locus_tag="LP245_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1519491.1"
                     /translation="MKRVALYMRVSTEQQAKHGDSLREQKETLYEYIEQHKDLKVVNE
                     YVDGGISGQKINRDEFQKLLQDVKENKIDLILFTKLDRWFRNLRHYLNTQEILEKHNV
                     SWNAVSQQYYDTTTAYGRTFIAQVMSFAELEAQIDSERIKAVMANKIAQGEVVSGKTP
                     LGYSIENKKLVINDDAPIVIDIFNYFLSSGSLRKTVYYLGSQYGIVRDYQSVKNMLTN
                     KKYIGELRNNKNYCPPIIDKKLFYAVQKALPKNLKTNAKRDYIFKGLLKCSDCQGSVA
                     GQTIKARYKKKDGTESIYERTCYRCVKRRNNKLRCTNKRAFYEKNLERYIFEATKQKF
                     EQIQINYSKKQPKIIKKKNSKKNIENKLDRLKKAYLNEVIDLEEYKKDREALMKELNE
                     IEVEPAKIDIKNVEFILSKEFDEIYKESSEEEKNALWRSIIDNIIVFPDGNITVNFLI
                     "
     gene            complement(20377..21666)
                     /locus_tag="LP245_001569"
     CDS             complement(20377..21666)
                     /locus_tag="LP245_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBL1519492.1"
                     /translation="MGVLLFLVGIVLIIMGSSKLSEAKKLKDKTSALESKVKEYSQEL
                     NARETFISEKEKNISKLNKNLSTLENKIDILNAESQRLDDEINQKYDTSLVTIYKSVI
                     IPNIDETSSSEIKNKLSLLKIKEKDFILDGAINIPSYLNNREANNIKKKMLIPLESEI
                     TGLLNKLTISNVDSTREKIIRTFDKINKLFKNDEAEFKKELLELKLQELELNYSYIVK
                     VNDEKEQQKAIKEQMIEEEKVRREIEREKKRIDKEERQFNSEITKLMAYMQKASADVE
                     KELYADKIKELEEKLRELETVKEDVLQRELNTRAGYVYVISNIGSFGEDVYKIGMTRR
                     LEPMDRIKELSSASVPFEFDVHAMIFSEDAPTLENQLHSHFRKNEVNKVNQRKEFFKV
                     SLDEIEKVVLENYNGTVSFTKLAQAEQYRRSLELTDV"
     gene            complement(21753..22457)
                     /locus_tag="LP245_001570"
     CDS             complement(21753..22457)
                     /locus_tag="LP245_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HBL1519493.1"
                     /translation="MFAENLKFLREKYNIDQQELAEKLGRKSSSSISEWEKGKYTPKL
                     KTLNEIAKIFNVDIDDLMNIDLSISNQIYNILPIYNQLNDENKVATYEFASNRLEEQK
                     QENVLDFPKKEKIPTVHNSASAANPTELTYGDTVVEEEEFERVPSAADFAVPIIGDSM
                     EPVIRNGQFVFVKEQPDVEDGEIAIVELGGDGVTCKEIYKDYENQTIILRSINDLYED
                     RIVSPEQIRIIGKVVF"
     gene            22657..22923
                     /locus_tag="LP245_001571"
     CDS             22657..22923
                     /locus_tag="LP245_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1519494.1"
                     /translation="MDTAKKEKYTLRQLRALKGYSKEELSRKSKVTSRTIFIYENDVD
                     KMRNGKYATLEKIAKALGVRVSDIFLDPDSEKPKSITGETKQVS"
     gene            22936..23094
                     /locus_tag="LP245_001572"
     CDS             22936..23094
                     /locus_tag="LP245_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519495.1"
                     /translation="MEEKNIKVPTLEEYTKIVVETDEQNPKTIAVITANDIESCEGFR
                     VRMTPRYD"
     gene            complement(23091..23321)
                     /locus_tag="LP245_001573"
     CDS             complement(23091..23321)
                     /locus_tag="LP245_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBL1519496.1"
                     /translation="MGKNQWVSPRNGKWAVRGEGNSEDTKLFDNKSDAVEYGKKISKK
                     QQSEFIVQKKNGQIQSKDSFGNDPIPPRDKEH"
     gene            23393..23548
                     /locus_tag="LP245_001574"
     CDS             23393..23548
                     /locus_tag="LP245_001574"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519497.1"
                     /translation="MSNKPKITLNGTPNLQRLADEMARIRSRHWGVTVVATIIEQKEK
                     PTQPASK"
     gene            23705..23860
                     /locus_tag="LP245_001575"
     CDS             23705..23860
                     /locus_tag="LP245_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519498.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGEKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(23857..24081)
                     /locus_tag="LP245_001576"
     CDS             complement(23857..24081)
                     /locus_tag="LP245_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBL1519499.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSPGNDPHPPKG"
     gene            24348..24683
                     /locus_tag="LP245_001577"
     CDS             24348..24683
                     /locus_tag="LP245_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519500.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            24916..25857
                     /locus_tag="LP245_001578"
     CDS             24916..25857
                     /locus_tag="LP245_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBL1519501.1"
                     /translation="MSKSTLEMSHQEWLEDRKRGIGGSDVATVLGLNKYKSPYQLWLE
                     KTGQIELKDLESEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPVIDGSGATADFLKEKYADVEENQTA
                     LPSRFDELIEQKRELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEKGIK"
     gene            25859..26749
                     /locus_tag="LP245_001579"
     CDS             25859..26749
                     /locus_tag="LP245_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBL1519502.1"
                     /translation="MATNESLKNQLAEKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            26792..27592
                     /locus_tag="LP245_001580"
     CDS             26792..27592
                     /locus_tag="LP245_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBL1519503.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWSLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            27607..28458
                     /locus_tag="LP245_001581"
     CDS             27607..28458
                     /locus_tag="LP245_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1519504.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGSIA"
     gene            28455..28814
                     /locus_tag="LP245_001582"
     CDS             28455..28814
                     /locus_tag="LP245_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBL1519505.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            28829..28990
                     /locus_tag="LP245_001583"
     CDS             28829..28990
                     /locus_tag="LP245_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBL1519506.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            28987..29313
                     /locus_tag="LP245_001584"
     CDS             28987..29313
                     /locus_tag="LP245_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519507.1"
                     /translation="MSVDKEAAWRKLMLLIQDENWQEDEAVVAEVQRLGKIANGRIRK
                     KPDKRKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYK
                     YLEEEK"
     gene            29310..30125
                     /locus_tag="LP245_001585"
     CDS             29310..30125
                     /locus_tag="LP245_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBL1519508.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
BASE COUNT        10206 a         5060 c         6158 g         8807 t
ORIGIN      
        1 taaataaagc ttatgcaaag aaaaagaaat ccaatcactt gggtttcttt ttcttttatt
       61 attatgatga atcaagcttt ctgtttttgt cacgtatgtt gtaatcttta cgaaagagta
      121 gagttggcta ctcataatca accatacttc ccatcatcgc taaatacgaa ataaatcagc
      181 attcctacac caatcaaagc acaagctgca ccaagaaaag ggatgacatt cccaaagtta
      241 tctgtattca taagtatgcc accacccaca aacaaaaagc cgccagcaat caggtttttc
      301 attttattca tctcctttct tacgttatag tatttccttc tttcaatgag tattttgaaa
      361 gctatcttat tgtatgatgt tcttctaggc ctcttcttta ttatacaggc cattttcgtt
      421 atctcataga aatattcctt tttatctgaa aactattgta taccgtatga catttttctt
      481 catgaagttg taagtatatt ctcattcaaa tgaaaatttc atcatagaag agattgtatt
      541 tctaaattct taagagtaaa atacgaagta taacttggat ttggaaggat gattggatga
      601 aagctattac gcctgatatg acaacaaaat ttaacaaaca gtttcaagca aatatcaaac
      661 agcaggcatt gcagcgggca gttgtgaaga acggaattac tgcttctgct gaaaatgttt
      721 cagcacatgt ggagaataca ccggtatttt ctatagattt ggctacgggg aaagtggcta
      781 atcaaatgca atcggggcgt tgctggatgt ttgctgcact gaacacattc cgtcataaga
      841 tgctgaatca attccattta aaagagtttg aattatcaca aaattacact tttttctggg
      901 ataaatatga aaaggcaaat tatttctatg aaaacatcat tgcaacagga aaagaggcaa
      961 tcgatagccg gaaagtagct ttcttactcg ctactcctca acaagatggc ggccaatggg
     1021 atatgatcgt ttcattattc caaaaatatg gcgttgtgcc taaatcggtg atgccggaaa
     1081 gtgcgaatag ttcaaattct cgagatttga ataactactt gaacaaatta ctgcgtaaag
     1141 atgcagtagt gttacggaaa atggttgctc aaggagaaac attagacgct attgaagaaa
     1201 agaaagaaga aatgctagaa agcatttata acttcttagc tatctcatta ggaacacctc
     1261 caaaagaatt cgattttgag taccgcgatg aagaaaagaa ctatcatctt gaccgaggac
     1321 tgacaccaca aattttttat gataaataca tcggtgtaaa attagatgat tatgttagcg
     1381 tgatcaatgc accaacaaaa gacaaaccat tcaatcgttc ttatacagta gagatgctag
     1441 gaaatgtcgt tggcgggaaa gaagtcaaat atctgaatgt tgatatggaa actttcaaaa
     1501 aattagcgat tgctcagctt gaagaaggag aatctgtttg gtttggttgt gatgtaggtc
     1561 aatcttctac tagaactagt ggcatcatgg ccttagatgc ttattcaatg gatgatctat
     1621 ttgatacgga ttttacaatg actaaagctg aacgtttaga ttttggagaa agtctgatga
     1681 cccatgcgat ggtattgacc ggtgttgact tagtagacgg gcaatcaaca aaatggaaag
     1741 tcgaaaatag ctggggcgaa aaagttggaa agaatggctt ctttgttatg agtgatgcct
     1801 ggatggacga atatacgtac caaatcgttg taagaaaaga tttattgacg aaagagcaat
     1861 taaatgcgtt caatgaagaa ccaattgttc tatctccgtg ggatccaatg ggtgctttag
     1921 catagacgag tatttcaatg aagagtatgt agtaaagata aaaagagctg gcttaagcca
     1981 gctcttttta tctttaaagt ccattccctg ttttttatgg tccctgtgct ataattctaa
     2041 ataaaggata aggattggaa ataatccttt tatcattaaa aatatgatga cgaagtagaa
     2101 taaaattggg agtagggggg aaagtcatgg atatccaaac tgttttatct gatctgaaat
     2161 taaatggtaa agtgattcca gttgttggtg gcgatgttaa tcagacctat cgtataaaaa
     2221 ccgaacatcg tgcttatttt ttaaaaatcc atccgaatgt aaaaaaagga ttttttgaag
     2281 cagaagtaga cggattaaaa gaactgtcag cattcgtacg tgtaccggat acgtatatgc
     2341 taggtgaaac aagtgaaggc gcttatttgt taatggaatg gatcgagccg ggaaaagggg
     2401 atcaacgaga tcttgctgca gctttagcta atctccatca gcaaacagcg ccacaatttg
     2461 gttttcgtaa agataactat ttgggtacac ttgttcagaa aaattctttt gaagaagatt
     2521 ggtggacttt tttctttaaa gatcggcttg aatcccagat ttctttggca gaagaaacga
     2581 atcgatggaa tgtacagcgt caagaaaagt atctgcgatt taaagaacgt gtattgaaat
     2641 cggttgaacc aaaaaagatc actccacgcc tcttgcacgg agacctgtgg agtggtaatg
     2701 tgttctttga ccagcaaggg catccagttt ttgtcgaccc agctgtttct tatgggaatc
     2761 gggaacaaga tattgcaatg agccagttat tcggtggttt ccgaccggaa tttttagatg
     2821 cttatcaaac tatatttcca ttagaaaagg gatggaaaga ccgactgccg atttaccagt
     2881 tatattatct tttggcacat ttgaatatgt ttggagaaag ttacggttcc caagtagatc
     2941 aattactaga aaatttttaa gaggagggcg tgtttttggc aaaaaaatat accaaaaagc
     3001 atgaagtttc atattatgag tgtgacatca accaaacgat gacatttcct tcgatgttag
     3061 gagtagttat caaaacgtct gaagatcaaa gcgaccagtt gggaagaggc agtgaattcg
     3121 tcaatagctt tggacttact tgggtcatca cgaattattc catggagatt aatcgtctcc
     3181 ctagagtcgg tgaagtaatc tcagtaacga ctcaagccat ggagtacaat aagtttttct
     3241 gttatcggaa cttctggatc catgatgaag atgggaaaga attagtcaaa atagaatctg
     3301 ttttcgtatt gatggatttt gtgaatcgaa aaatgagcag tgttaatgaa gagatcattg
     3361 ctccttttga gagtgagaag atcaagaaaa tcaagcgtca ggaaaaaatt gaaaagattg
     3421 attcgggctt catgttgcca tatcgtgttc gtttttatga tatcgatagt aatcagcatg
     3481 ttaataatgc gatgtatttt aattggatca ttgacgtatt aggatatgac tttttgacta
     3541 cgcatgttcc agaaaaagta attattcgat ttgataaaga agtagagtac gggaatgaga
     3601 tcgaaagcca ttttgaacaa atccctatcg aaaatggtgt caaaacaaaa catgaaatcc
     3661 gaatgcaaga acagctgtat tgtgaagcaa atattatatg gaaaaataaa taaaaaagag
     3721 gttgtgacag aagggggcaa cttcaagaaa taagaagaaa tttacgaaaa ttgtttctca
     3781 aatttttgta aattttcgac ttagttttcg aagaagctat ttttgtcaca gcctctcttt
     3841 ttaagtttag ctattagata atgatgttta gttttggata aacgaaatca attcttcacc
     3901 cgacaaacca tagtttacag caatcaatag ttttaaacgt gctttttgac tattaatact
     3961 gttacagaaa ataatcccca ttttttctag ttcttttccc ccgccttcat aatcataaac
     4021 aggctctgcg attccattga aacaacgaga aacaagtact acagggattt tttggacaag
     4081 aagcttttcc aaagcagcta aggcttgtgg agggagattc cccgcaccta aagcttcgat
     4141 taccaaaccg tctactttcg tatgggcgat ggcttccaat aagtcccctt gcatcccagc
     4201 atatgcttta acgatcggga tagtcccatc tacagcggaa atgtccagtc gctttgtttc
     4261 taaaagttcc tgcaagaata aaattcgatt cttagttact aagccgatgg gacccaatgt
     4321 aggtgttcgg aaagtagcaa catttgtggt atgggtcttt gtcacgtagc gtgcagaatg
     4381 gatctcatcg ttcatgacca ccaaaacccc cttatctagc gcttcttcac aacttgcgac
     4441 acgaatcgca ctttcaaaat tataaaggcc gtcacttcca agttcattac ttgaacgcat
     4501 tgccccagtc aaaacaattg gtaatttgtt gccaatcgtt gtatcaagaa aaaaagcagt
     4561 ttcttctaat gtatctgtac cgtgtgtgat caccactccg gatatacctg atgcataagc
     4621 ggacaagata cgttctttta ataccaacat gtgagaaggc atgatgtgtg gtgagggaag
     4681 attgaagata tcttcaacta ataattctac atgcttgggg attgtgattt ctgcatctaa
     4741 taatgggttt gccacatcag gactaacacc gcccgtgagc atgttttctt tcatggcgat
     4801 cgttccgccg gtgtgtagta caagtatttt tttcatttta cagacttcct tacgaataat
     4861 tttgcatagc cgttaaatct tattgtatac tatataaaag agttttgcta tcagtgaaga
     4921 ataacgaata gcctaactta tcataaaaaa gctgacctta ttaaaatgga aaagactcaa
     4981 ccttgacctc ctaatacaat ggagtatctg gttgagtttc ttttacaaga aagcagccaa
     5041 ggaaatcaat cacgaaggtg gccggaaatg atcagaatcg gattaacatc gtttaaagaa
     5101 catgacaaat taactggtaa aaagaataac actctttatg aatatgcagg gtttctaccc
     5161 ttagtggaat tagatactgc ctattatgga attccccgaa agtcctcagt tgagaattgg
     5221 ataagtgaag tacctgaatc atttcgcttt gtagtcaaag tctatcaagg aatcagcggt
     5281 caaggagact ggaagcctta ttatcagacc gaagaagaga tgattgcgca ttttttagat
     5341 gttatgtcgc caatggtaga tgctggaaag atgttttgct ttttagtcca attcccctca
     5401 tcattcaaat gtacgaaaga aaatgtccag tacttgcgca aacttagaaa gtggtttgag
     5461 ggttatcctg tttctataga attgcgggat tattcttggt acagcgatga atttcttgaa
     5521 cgtacaagaa actttatgtc tagagccgct ttttctttag ccatcatcga tgagccacag
     5581 ttgctgaata caacgattcc ttttgatcca tttgtcacca atccgaactt tgctcttttt
     5641 cgattccatg gtaggaatgc gcaaggatgg caagcaaatg ataaagagtg gcgtaaaaaa
     5701 agaacgttat atcgttattc agaaaaagaa ctgcaagaac tagcacatga agtcaaagta
     5761 gttgattcta agacaaaaga ggtaggtgtg atttttaata ataattctgg tggtgatgcg
     5821 gctgaaaatg cattagcact gcaaaaaata ttaaatatca agccagatgg actcaatcca
     5881 acccaaatgg atctgtttta agggcttatt ttattcaaga aaggggcgaa gtctatgatc
     5941 aaagctattt tttttgatat tgacggaaca ttggtcacca atcgttcaaa agcgttggaa
     6001 tcaacaaaac aagcaattga atatgctcgg aaaaacggca ttttatgcgg tgtagcaacg
     6061 gggcgcagcc cagtaaagat caaagaaatc attgatgaat tggaattaga tatgtatgtc
     6121 gtgtataatg gtcaactggt ttttactgca gatcgcacga ttatcgacca cccttttgaa
     6181 caaaaagtat tggaacatat tgttgaattt gcagatgaga accatcgaca aatcgttttt
     6241 ggtgcgagaa atcggttaga tggatcaacg acgatgctat taggacaatc gatttttatc
     6301 aagcgactag tcagcttttt accgcgtaaa ttcccggtac gtctgatgaa aaaaatcctc
     6361 caggttttta gccctcaccg acaaaaggat cgttatgaaa cgttagagat attaaaagaa
     6421 ccaatttatc aatgtatatt gctcagtccg gagtcagaac agaaaaagtt agaacatcgc
     6481 tttcccgagt gtacgtttca gcgttcaaat acgtatactg tagatatcat cccaaaaggt
     6541 ggttcaaaat tactaggcat ccaagctttc gcaaatgctg tcgaaattga aatggaagaa
     6601 attatggcat tcggcgatca ttacaatgat atcgagatgc tgaaaggtgt aggaattgga
     6661 gtggccatgg ggaatgctca gatcgaagta aaacatgctg cagactttgt gactcaatca
     6721 aatgaagaag atgggatata cgaaggactg aaacacttcg gtctgattta ttagtcaatg
     6781 aaagaaggaa aaaatcagta tggaagcaga gacacctttt caaaaagtag aaacattcca
     6841 caaaactttt gatccaagaa gaccagagat acccacggct tttacagaaa atgaagctca
     6901 tacacgtgct gcgttcaaaa tagaagaact tgttgaattt gttgcagcta cttcacctaa
     6961 taaagaacaa ctgcatgaag ctgttatgct gctgcacgaa gcattagata aagcagaaga
     7021 aaaaatactt ggtaaaacac agtggggaag tgatccgctg gttgaacaag tagatgcact
     7081 gacagatatc ctttacttta cttatggttc tttttcatta ctaggaatag tgcctgatcg
     7141 aatattcgaa atcgtccatc aggcaaatat ggggaaatta tttccagatg gaaaacctca
     7201 ttatgaccct gtaacaaata aagtgttgaa acctgaaaac tggcagatgg aatatgctcc
     7261 agaacctaaa atcgcggcag aaatccaacg tcagattcaa gaagcgattg ctaagaagaa
     7321 atccgctgat ataggcatgt gcacaaatga aaaagagtga tcagagtttc actatttttg
     7381 ttatctttat acgatggaaa aacaaaagat tttcgtttaa gttagtgaat gcatgaaaat
     7441 agtatgctat aatctagaat agatgtcttt tgcacgagag acgtattatt tggatttatg
     7501 ccaagcagaa cgccatctgt tgcataaaag atgcatactg aaaacggagg aaccataaat
     7561 gggaaataat gttatcatcg gaatcgtcat tgcaatcatt atagtcgcca ttgtcgtctt
     7621 tttggttagt tacttgatga agaaaaaaaa ccaagatcga ttggatgcct tagaaaaacg
     7681 caaggaagaa ttatttgact tgccagtgat tgaagaagtc gatgatgtta aaaaaatgca
     7741 tctggttggg caaagccaaa atacctttcg tgaatggagt caaaaatgga atgacatatc
     7801 tacttcctcg ttcgctgaac tagaaagtca aattttcgaa gtggaaaacc tcaatgaaag
     7861 ttttcggttc ttaaaaggaa aaaaagcagt tgttgaagca gaagctacaa tggaccaaat
     7921 ggagaaacaa gtgacggaaa tccgtgaagg tctaaaggaa ttgcgggaaa cggaagaacg
     7981 caactcacta gctgttcagc aggcacttga cgtctatgaa gaactgaaag aaaaagtcag
     8041 agaagacgag catgaatacg gaccagctct ttttgaattg caaaaacaga tcaaagtgat
     8101 cgaaaaagaa tttacgcagt ttgtgacttt aaacacttct ggagaccctg ttgaagcccg
     8161 cgaggttttg gataaagcag aaaaacatac gtatgaagtg gaagctctga tgaaaaaaat
     8221 tccaccgctg tatgaggagc tccataccac tttccctgaa caacttgaag aaatcagtga
     8281 tacttacgag aaattgatgg aagaacaata tgtattccca gaagaagatc ttgctgaaga
     8341 tatcgcaaaa gtaagtcgaa gaattgaaaa ttcattagcc aatcttgaaa aaacagaagt
     8401 tgaaacggtc gaatttgaaa accgtgaaac agctgatttg attgattcgt tatatgatat
     8461 cttagaacgg gaaatggaag ctcagagata tgtaaaaact aaccaatcaa cgattgcaga
     8521 gtatatcaaa catacaacaa agaataaccg tcaattattg attgagctgg atcacacatc
     8581 tcaaagctat acattgaacc acaatgaaat tggccgtgta cgaggtttcc aaaccgaagt
     8641 ggaagaaatg gaacgtcaaa atgaacagat gattccacag atccgtcaac acgaaattcc
     8701 ttattcagaa gtgcgcacgt tctataaaac agtcttcaaa gtcttagaag atatcgaaaa
     8761 gcaacaagta gagatcgacg actcattaca tgaattgaga aaaggcgaaa aagaagcgca
     8821 agaaaagatc gatacattcg aattcaaatt gcgcagtttg aaacgttttg tagaaaaaca
     8881 acgtttgcct ggcttgccga atgattacct agaattcttt tttgttgcta ctgaccgtat
     8941 tgaagaacta agtgttgtct tgaataaaat tcgagtaaac atggaagagg tcaatcgttt
     9001 agttgctcta tgtgaagaag atctagaatt attagataag aagacacatg atttagtaga
     9061 tgcagcagca ttaacggagc aaatgctcca atatgcaaat cgttatcgtc atacacacga
     9121 agaagtgaga gaagcaattg ataaaagcta ctatttattc aataaagaat atcactatca
     9181 agaagcatta gacgaaatcg gtacagcatt agagcgagta gaacctggtg ctttcaaacg
     9241 catcgaagat ttttatttta atcatccaga cttagtataa agcaaaaaag ttagtaaacc
     9301 agcaagagca agacggatta ttgtcttgtt cttgtctttt tttgtatatt tgaaaattga
     9361 aacaagtgaa aatttcacct gctcttgaaa gcaccttgga caaccgttat aatagaaaag
     9421 aatttcaaaa aagaggggtt tcttatgata tattttgata acagtgcaac aaccccaatc
     9481 tttccgcaaa gcttagatgc atatgtaaaa accagtcagc ggattattgg gaatccatca
     9541 agcttgcatg atttaggcaa tcaagctaac cggttgttgc agcaagcaag aaagcagatc
     9601 gctgatttga tccatgtaga accagaagaa atctatttta cttcaggcgg aacagaagga
     9661 gataactggg tattaaaagg aacgatgatc gaaaaaagag aatatgggaa tcatatgatc
     9721 atttcaggag tcgaacatcc ggccgtcagc gagacagcag aacaattaaa agaattagga
     9781 atcgaagtaa gtatcgcccc agtggataaa cgcggatttg tacgtgtcga cgaattgaaa
     9841 gaattaataa gaaaagagac agtattagtc tctgttatgg ctgtgaataa tgaagtagga
     9901 tcgattcagc ccatccagga aatcagtgat cttttggatg attttcctaa aattcatttc
     9961 catgtagatg ctgttcaggc gattggaaaa gtaccattct cgcaatggtt gacagaaaga
    10021 gttgattttg caacattttc agctcataaa ttccatggcc cacggggaac tggtttcatt
    10081 tattggaaaa agggtcgtcg tttagcacca ttactgacag gtggagggca agaaagaaat
    10141 cagcgaagtg ggacagaaaa tgttccaggt attgtggcta tggttaaagc tttacgttta
    10201 tcattagaga taaaggaaca aaaacctgag cagacacaac gcttaaaagt agctctaatc
    10261 aatgcgttga agacgtatga gaaagtgacg attttttcag aaggaactga ctatgcaccg
    10321 catattttat gttttgctct aaaaggaatt cgcggcgaag ttctcgtcca tgccttagaa
    10381 gaaaaacaaa tatttgtttc tactactagt gcctgctcct cacgtaaaca tatggcaagc
    10441 agtacattgc acgcaatgca tgtaccaaat gatctggcta catctgctgt tcgaatcagc
    10501 ttagatgaaa acaattcgct tgcagaagtc gagcaattta tgattatttt caagcagctt
    10561 tataagaaat tttctgcaat caattaaaag aggagtgttc ttgtgaaata cagtgaaatt
    10621 atggtccgtt atggggaact ttcgacaaaa ggaaagaatc gaaaaagctt tatcatgcaa
    10681 ctagcacaaa atgtcagaca agctttgaaa gactttccag aaatcaaaat ccatgctgat
    10741 cgggaccgga tgcatctttt attgaatggc gcagacgggc agctagttat tccaaaacta
    10801 gcaaaaatat ttgggatcca aaatttctct ccaagtattc gtgtagaaaa agatgtcgaa
    10861 gttttgaaac aagctgttca agacatcatg aaagaaattt atactgggaa agaaacattt
    10921 aaaattatcg ctaaaagaag cgatcaccaa tttgaattga caagtaatga attgaatcaa
    10981 acattaggta atgctgtttt tgatattttc ccgcatatcc aagttcaaat gcgtcaacca
    11041 gatattccat tacgtgtaga gattcggcgt gatggcgctt atctatcgta tgaaacgatc
    11101 aagggagctg gaggattgcc cgtaggaaca agcggaaaag gaatgcttat gctttctggg
    11161 gggattgatt ctcctgtagc agggtacttt gccatgaagc ggggagtgga aattgaagct
    11221 gttcattttg ctagtccgcc gtatacaagt gaacaagcac tgcaaaaagc aaaagatcta
    11281 acagccaaac tagcacctta tgtgggaacg atccatttta tcgaagtgcc atttaccgag
    11341 attcaagaag aaatcaaaaa gtcagtgcca caaggatatt ggatgacaat tactcgtcga
    11401 atgatgttgc gtttgaccga tgaaattcgc cgtattcgtc atggtttagt cattttgaat
    11461 ggtgaatcat taggtcaagt ggcttcacaa actttgcaaa gtatggtggc tatcaatgaa
    11521 gtaacgaata cgccaatcat tcggcctgta gcgacaatgg ataaacttga aatcattgaa
    11581 gtagcagaac agatcgatac atttaatctt tctatccagc cttttgaaga ttgctgtacg
    11641 atttttgctc ctccacagcc aaaaacacgc cctcaactgg aaaaggtcca tcaatatgaa
    11701 gagcgtttag caatagatga aatgatccaa cgagcactag ctggcttgaa gatggaagag
    11761 atacaagcag aatcgtctaa tgaaaaaact gaagaatttt cagaattgct ataagaggtt
    11821 atgaaaatag tgttttgacc agagtattag agaaacaaaa cgaaaaaata gctccatgta
    11881 ttttaccgtt tttgaactaa tgtcgaagat tagctgattg aataccattt atcaagaagt
    11941 tatggaaaag ccggttcttt tttactaact gaaaaataaa attttattta gagatcaagc
    12001 tacagttgat aaatgatata aaaaagagaa tttcccatga aatagcgagg ttgtgacaga
    12061 agtgggcagc ttcaagaaat aagaaggaat ttacgaaaat tgcttttcaa atttttgtga
    12121 aatttcggct tatttttcga agaagttact tctggaacac cgtgtatcag aggttgcgaa
    12181 aaagctgccc tgcatcaagt aataagaaca gccaaacaaa aatagttcct catattttac
    12241 gtttggttga gcttattacc gcagatgcaa gcttttgaac accgttttat ttgtctcaca
    12301 cccttttcct tcctacttgt aaccttgctc ccgtgttaga aacatgttac actaaatatg
    12361 tgaaattatt aacaaggagc gtcgttatgc gagaaaaaac agatacactg ccaaaagcaa
    12421 ctgcgaaaag attaccttta tatttacgct acttgaagat gctggatgac tcaggtataa
    12481 gtagaatcaa atcaaatgag ttcagcgaaa tcacccaaat tccttctgca acgatccgca
    12541 gagacttctc gcaattaggc gagctaggca gaagcggata tggctatgat gtcccttttc
    12601 ttatcgatgt attcaataat atccttaata ctaaagaaga aaaacgaatc gcattagtag
    12661 gatatggaaa tcttggcaaa gcattgaaac acaacaattt tagaagaaat gaaaatctaa
    12721 atatcgtgtg cgtctttgat aatgatccag cactgatcaa tcgagtaatt gatggagaaa
    12781 tgatctatcc gattgatcgt ttcgcggaga tagccaaagc aaaaaatgtg acagtagcaa
    12841 tctctacggt accaagtaaa tattcacaat ctgctattga tgaaattgtc aaaggaaatg
    12901 taaccgctat acttaatttt gcgcctgaca gagtaactgt cccagcttat gtcaatgttc
    12961 aatacattga tttgacaacc gagttgcaga cgcttattta ctttgatgag aattactcag
    13021 aagttttttc ttaggaaaat ttgagtaggc ttattgatct tgcgagaact cgtcgtaatt
    13081 ctttcaaaaa ttttttagta ctaaatgaag tggttttttc acgaccactt gttgactaaa
    13141 aaaaaaaacc attgtagaat gaagcataac gctgaacaag aggagtaact ggcacattca
    13201 ttcttagaga gagaactatc tgctgaaagg ttctcaatga caaccagtga aggtagcttg
    13261 ggagtttctg tcttgaatgg agtagagata gacgagtcgt gatcgttaac tcacttgaga
    13321 ggcaataatg attgattatt gcaatttagg tggtaccgcg taaatcatac gtcctagaat
    13381 acgaaagtat tttaggacgt tttttagttt aaaggaggaa aacagcatga cggaagaaaa
    13441 taacctatca acaaaatata atccgcaaga agttgaagct ggacgttatc agcattggtt
    13501 agaacaagat ttgtttaaac cgagcggaga taaaaaagca aaaccttatt caatcgtaat
    13561 cccgccccca aatgttactg gaaaacttca tttagggcat gcttgggata cgaccttgca
    13621 agatatgctg attcgtcaaa agagaatgca aggatatgat actttatggc tgcctggtat
    13681 ggaccatgca ggaatcgcga cacaagcaaa agtagaagcg aagcttagag agcaagggat
    13741 ttctcgttat gatctaggtc gtgaaaagtt catcgatcaa gtgtgggaat ggaaagaaga
    13801 gtatgcgagc cacatccgcg aacagtgggc taaaatgggc ttatctttag attacagtag
    13861 ggaacgtttt acattagatg atggattatc tgaagcagta cgtaaagttt ttgttacctt
    13921 atacgaaaaa ggtttgattt atcgtggtga atatatcatc aactgggatc ctcaagcacg
    13981 aacagctcta tctgatatcg aagttattca taaagatatc gaaggcgcct tttatcatat
    14041 gagctatgaa ctagcagatg gatcaggcgt agtagaaatt gcgacaaccc gtccagaaac
    14101 gatgttggga gatacggcga ttgctgttca tccagaagac gagcgttatc aagcgctcat
    14161 cggcaaaaaa gtgattctac ctttagtcaa taaacaaatc ccaatcattg cagatgaata
    14221 tgtagatatg gaattcggga caggtgtagt aaaaatcact ccagcacatg atccaaacga
    14281 ctttgaggta ggtaatcgtc atgatcttcc acgcgtaaat gttatggatg atgatggtac
    14341 gatgaatgaa ctagcaggaa aatatgctgg aatggaacgt tttgctgctc gtaaagcaat
    14401 cgtgcaagat ctgaaagaaa tcggtcgatt gattaaaatc gatacgatga tccacagtgt
    14461 gggtcattcc gagcggacag gtgtcgttgt tgaacctcgg ctgtctactc aatggtttgt
    14521 aaaaatggcg ccgttagcga aaaaagccat tgataaccaa gaaacagatc aagcagtgga
    14581 attcttccct ccaagattca atcaaacgtt tttacgttgg atggaaaatg tccatgattg
    14641 ggtaatctca cgacaattat ggtggggaca tcaaattcct gcatggtatc acaaagaaac
    14701 aggtgaaatg tatgtaggga tggaagcacc agcggatagt gaaaactggg tacaagatcc
    14761 tgatgtttta gacacttggt ttagttcagc tttgtggcct ttctcaacaa tgggctggcc
    14821 agatacggaa agcgaagatt ataagcgata cttccctact agcactttag taaccggtta
    14881 tgacatcatt ttcttctggg taagcagaat gattttccaa agcttggaat ttactggcga
    14941 acgtccattt gagaatgtct tgattcatgg attgattcgt gacgaacaag ggcggaagat
    15001 gagtaaatca ttaggtaatg gaatcgatcc gatggaagta atcgaaaagt atggagcaga
    15061 tgctctccgc tggttcttat cgaatggttc tgcaccagga caagatgtcc gcttcagcta
    15121 tgaaaaaatg gatgcttctt ggaactttat caacaaaatc tggaatgctt cacgtttcgt
    15181 tatcatgaat atcgaaggaa tgaccgtaga agagatcgat ttatctggag aaaaatcagt
    15241 ggctgaccgg tggatcctta ctcgtttgaa tgaaacgatc gaacgagtaa ctgagctatt
    15301 tgatcgtttt gaatttggtg aagcaggtcg acaactgtat aactttatct gggatgattt
    15361 ttgtgactgg tacatcgaaa tgagtaaaga agtactttat ggagatgatg ctgtttcaaa
    15421 acaaaccacc cgtagcatct tagtccatac acttgatcag atcctacgtt tattgcatcc
    15481 aatcatgcca ttcgttacag aagaaatatg ggaacatatt cctcatcagg gaaattctct
    15541 agtagtggca gaatatcctg ttgtacgtcc agagtttgat gatgaaacag cttctaaagg
    15601 gatggaagta ttgaaagaat tgattcgagc cgttcgaaat attcgttcag aagtgaatac
    15661 accattgtct aaaccaatta cgttgctaat taaaacaaac gatgctaaaa tcgatcaatt
    15721 tttagttgaa aatacaagct atatcgaacg cttctgtaat cccgaagagt tgacgatatc
    15781 aagtgagatc actgcgccag atctagcgat gtcagctgtt ctgacaggtg cagaaatctt
    15841 cttgccgtta gcaggattga tcaatattga agaagaaatc aaacgattag aaaaagaact
    15901 ggaaaagtgg acaagcgaag taaaacgtgt ccaaggaaaa ctttctaatg aacgttttgt
    15961 ttctaacgcg ccggaagaag tagtagaggc agagcgtgca aaagaaaaag attatttaga
    16021 gaagcaaacg gctgtcaaag aacgaatcga aagtttgcgt actattcaat aagaatagaa
    16081 aaagagagtg tgaaatcagc tagctattac taaaagctag ctgattgaac atcgttacag
    16141 gaaagagttt gagcctcact cttagcttcg attcataagg agatgtgaca taaattttgt
    16201 cgcatctctt ttttagtcta ctcttattat gtaggagaag gagggaggtg gatcatgtat
    16261 caagagtcaa taaagtagtt gataaaatcg ttcctctctc tgtttctttt ctctttgtca
    16321 tacttttatt tttcttatgt gttctatttg ttataataaa agagaaatgg gggaattgtt
    16381 gatgacgatt gaagaagcaa tagaatggat ccatagtcga ttaccatttg gttcacgtcc
    16441 tggccttgac cgagtcgaag ctttattaga agtggtaggg catccagaga gaaaagtaaa
    16501 aacgatccat atcgctggaa caaacggaaa aggttctact gtagcttatt tgagaagcct
    16561 attagaagag gctgggctga cagtaggtac atttacttca ccttatatcg aaacgttcaa
    16621 tgaacggatc gcaatcaatg gcaaaagcat tccagacaat gatttgatcc agcttgtaaa
    16681 aaaatatcag ccactgatca aacaacttga tcaatttgaa gcagtagctg gtattactga
    16741 attcgagaca ttaacagcaa tggcatttga ttattttttg atgaagaaag tggacgtagc
    16801 gattatcgaa gttggcttag gcggcttatt ggattctacc aatgtagctg taccaatgct
    16861 gacgggaata acaacgattg gacttgatca taccgaaata cttggagata caattgaaga
    16921 aatcgctgca caaaaagctg gaatcatcaa acaaggcgtt ccagtagtaa caggaaatat
    16981 tgccccagaa gcttttactg tcatccaaca aacagctaaa gcaaaaaatg caccgcttta
    17041 tgtatacggg gaaaattata aaataaacta tctgcatcct gatgagatgt ggggagaagt
    17101 atttgaattt tttaatgaaa taggaaagat ccctcaatta accactccgc ttttagggca
    17161 acatcaagct gaaaatgcag gagtagccat cgaattgtat tttgtttact gtcaattgga
    17221 aaagctgcct ttccgagaaa aagatgtttt gaagggattg aagaaatctc gatggccagg
    17281 aagaatggag cgtttgagta acgagccatt agttgtttta gatggtgccc ataatacgca
    17341 tgcaatgaac cggcttgttg agaatttgaa aaaagaattc aaaggatatc aaatcaacat
    17401 tttgttttcc gccttacgaa ctaaaaatgt tagagaaatg ctagaacgat tgcagcaagt
    17461 accaaatgtc catatttatt tgacgacctt tgaacatcca aaagccatcg aattaagtga
    17521 agtatcagat ttagcaagtg agagagtatc aatcgtttca ttgtggcaat tcggattagc
    17581 agatatattg gaaaagatga caaatgaaga cgtattagtt gtgaccggtt cactttattt
    17641 catttcagaa gttcgccatt tattaataca attaggagga gatcatgaag tataatgcag
    17701 tgatttttga catggatggt ttgctgttcg acacagagtt agtgtattac gaagccacac
    17761 aagtagtagc agacaagatg ggttttcctt atgataaaga cctgtattta aaattcttag
    17821 gtgtttcaga tgaagaagta tgggcgaatt atcatatgat tttctcggaa tttggcaaaa
    17881 caagtgtaca aagattcata gatgattcat accaggaaac gcttgaacgt ttttcgcaag
    17941 gagcggtaca aatgaagccc ggtgtgttgg aactcctctc ttttttagaa gaacatcaga
    18001 ttcccaaagt tgtcgcttcc agtaaccaac gagcagtcat tgaactttta ttgaagaaga
    18061 acaatctgtt tgaacgattt gagacgattg tttctgcaga aaatgttcaa cgagcaaaac
    18121 cagacccaga aattttcttg ttagctaatc agaagctagg tacagcgaag aaagaaacat
    18181 tgattttaga agattcacaa aatggtattt tagcagcttc tgcggctgag atcccggtag
    18241 tcatggtacc agatctgctt ccaccatccc aagaattgat caaaaaaaca gctggggttg
    18301 tttcttcttt acatgaaatc cctgcattgt taaaataaaa atccatctct tttcgtatct
    18361 tattttagat aagatagaaa ggagatgttt ttttgggaaa acgattgatc aaagaagtac
    18421 ctactagctc tttaccaagg gaacgtatgg aaatttatgg cgcggaagct ttatcggatc
    18481 aggagctttt ggcaatctta ctgcgtaccg gtcaacaccc ttatagtgtg atgtcgattg
    18541 ctggaaatct gttaaaaacg tttggaggac tggcctcttt acgacaggct actttgcatg
    18601 agttagaaga gattcgaggg ataggacgcg tgaaagcaat cgaaatcaaa gccttgatcg
    18661 aattaggtcg acgaattcag acggatcatg aaagagcggc tccaccggtt cgtaccagct
    18721 acgaattggc ccagcaattg attctggaaa tgaaagatca caaacaagaa catttggttt
    18781 gtatttattt ggacacgaag aatcaagtga tcttaaaaaa aacagtgttc atcggttcgc
    18841 tgaatcagtc agtcgctcat cctagagaaa ttttccatta tgctgtacgt tattgtgcag
    18901 caaggatcgt tttagcgcat aatcatcctt ccggaatata taagttagta cacataaatt
    18961 atataaggaa atttactgtt atattgccat ctggaaatac tattatgtta tcgataattg
    19021 aacgccataa tgcatttttt tcttcttccg aagattcttt ataaatttca tcgaattctt
    19081 ttgatagaat aaattcgaca ttttttatat ctattttagc tggctctact tcaatttcat
    19141 ttaattcttt cattaaagct tctcgatctt ttttgtattc ctctaagtct ataacttcat
    19201 tcaagtaggc tttcttcaat ctatctaatt tattctcaat atttttctta ctatttttct
    19261 ttttaataat ctttggttgt ttttttgaat agtttatttg tatttgttca aatttttgtt
    19321 tagtagcttc aaaaatataa cgttctaaat ttttttcgta aaaagcgcgc ttatttgtgc
    19381 aacgtaattt attatttctt cgttttacac atctataaca agtcctttcg tatatagatt
    19441 ctgtaccgtc ttttttctta tatcttgctt taatagtttg accagctact gatccctgac
    19501 agtcagaaca ttttaataaa cctttaaaaa tgtaatcacg ttttgcattt gtttttaaat
    19561 ttttaggtaa ggctttttga acagcataaa aaagtttttt atcaataata ggaggacagt
    19621 aatttttatt atttcttaat tcaccaatgt attttttgtt cgtcaacata tttttaacac
    19681 tttgataatc tctaacgatt ccatactgag agcctaaata ataaacagtt tttcttaaac
    19741 taccactaga aagaaagtag ttgaatatat ctatcacgat aggagcatca tcatttatta
    19801 ctaatttctt attttctata gagtagccta acggagtttt cccgcttact acttcacctt
    19861 gtgcaatttt atttgccata acagctttga tgcgttctga atcaatttgg gcttccaatt
    19921 cagcaaaact cattacttgt gcaatgaaag ttctgccata cgctgtagtt gtatcataat
    19981 attgttgaga aacagcattc caagaaacat tgtgtttttc taaaatttct tgagtgttta
    20041 aataatgtcg tagatttcta aaccatctat ctaattttgt aaataaaatt agatctattt
    20101 tattttcttt tacatcttgt aatagttttt gaaattcatc acgatttatt ttttgaccag
    20161 aaataccacc gtctacatat tcattaacta ctttcaaatc cttgtgttgt tcgatatatt
    20221 catagagggt ttctttttgt tctctaagac tatctccatg tttggcttgt tgttcagttg
    20281 atactctcat atataatgct actcgtttca tgttatctcc tttcgaatgt atgttcttat
    20341 cgttgtaaaa gaaaagcccg aaggctaatc tttttactac acatctgtta attctaatga
    20401 tcttctgtat tgttcagctt gagctagttt agtaaaagat acagttccgt tataattttc
    20461 taaaacaact ttttcaattt catcaagaga tactttaaag aattcttttc gttgattaac
    20521 tttattgact tcgttttttc taaaatgcga atgtagttga ttttctaatg ttggtgcatc
    20581 ttctgaaaat atcattgcat gaacatcaaa ttcaaaaggt acagaagcgc tactaagttc
    20641 cttaattcta tccataggtt ctaaccgtct agtcattcct attttataga catcttcacc
    20701 gaaagatccg atattactga tgacataaac atagccagct ctagtattaa gttctctttg
    20761 caatacatct tctttgacag tttctagttc tcttaatttc tcttccagtt ctttaatttt
    20821 atcagcatag agttcttttt caacatcagc actagctttt tgcatgtatg ccattaactt
    20881 agttatctct gagttaaact gtcgttcttc tttatcaatg cgtttctttt cacgttctat
    20941 ttcacgtctt accttttctt cttcaatcat ttgttctttt attgcttttt gctgttcttt
    21001 ttcatcgtta actttaacta tgtatgaata gttgagttct aattcttgaa gttttaattc
    21061 aagtaattct tttttgaatt ctgcttcatc gtttttaaaa agcttgttta ttttatcaaa
    21121 agttcttata attttttctc tagttgaatc tacgttagaa atagtaagtt tattgagaag
    21181 tccagttatt tctgattcta atggtataag cattttcttt ttaatattat tagcttctct
    21241 attattcaaa taagaaggaa tattaattgc accgtctaaa ataaaatcct tttctttaat
    21301 ctttaataaa gaaagtttgt tttttatttc ggatgaagaa gtttcatcta tattcggaat
    21361 aattactgat ttatagatag tgaccagaga tgtgtcatat ttttgattaa tttcatcgtc
    21421 taaccgctgg ctttcagcat taagaatatc aattttgttt tctagcgttg acaagttttt
    21481 attcaattta cttatgtttt tctctttttc agatataaac gtttccctag catttaattc
    21541 ttgagaatat tcctttacct tactctctaa ggcagaagtt ttatctttta attttttagc
    21601 ttcagataat ttgctactac ccataattat taaaactatt ccaactaaaa acaatagtac
    21661 tcccattcaa aacgcctcgc ttcttttata aaataattgt caaaatcata taaaccctta
    21721 ccgaagttga cggctccggc atgggaattt ttttaaaata caacttttcc gataattcta
    21781 atctgttctg gcgatacaat tctatcttcg tataagtcgt ttatagaacg taaaatgatt
    21841 gtttgatttt cgtaatcttt atatatctct ttacatgtaa ctccgtcacc acctaattcc
    21901 acaatagcaa tttccccatc ttctacgtcc ggttgttctt taacgaatac gaattgtcca
    21961 ttcctgataa caggttccat tgaatcgcct ataataggta ctgcgaagtc agcagcactt
    22021 ggaactctct caaattcttc ctcttcgaca accgtatcac cgtaagtaag ttctgttgga
    22081 ttggcagccg aagccgaatt gtgaacagtt gggatttttt cttttttagg aaaatctagg
    22141 acattttctt gtttttgttc ttctaatcga ttacttgcaa attcataggt agcaacttta
    22201 ttttcgtcgt taagctgatt atatatagga aggatattat atatctgatt agatatagat
    22261 aaatcaatat tcatcaaatc atctatatca acattgaata tcttagctat ctcatttaag
    22321 gtttttaatt ttggtgtata ttttcctttt tcccattcgc ttattgagga tgaacttttt
    22381 cttcctagtt tttcggctag ttcttgttga tcaatattat acttttctct aagaaacttt
    22441 agattttcag cgaacatagt aacacctcct tgagttaatt gtaacaccgt ttcggaaaaa
    22501 atgtaacagg tttcttagaa aatattttag tgtttttaaa gaagtattta cgcaaaatag
    22561 aaatcgattt caggaaaacc gaaatatgca cttgacttcg gaaaaaccga agtatataat
    22621 ttagtcagaa agttaaagag aggaggcgaa taaaatatgg ataccgcgaa gaaagaaaaa
    22681 tatacattga gacaattaag agctttaaag ggttattcaa aagaagaact gtcaaggaaa
    22741 agcaaagtga catcaagaac aatatttatt tacgaaaacg atgtagataa aatgaggaac
    22801 ggaaagtacg ccactctaga aaaaattgct aaggcattgg gtgttagagt ttccgatatt
    22861 tttttagacc ctgattcgga aaaaccgaaa tcaataacag gtgaaacaaa acaagtcagc
    22921 taggaggtgt gaatagtgga agagaagaat ataaaagtac cgactcttga agaatataca
    22981 aaaattgttg tcgaaacaga cgagcagaac ccgaaaacaa tcgcagttat tacggcgaat
    23041 gatattgaat catgcgaagg ttttcgagtt cgaatgaccc ctagatatga ttaatgttct
    23101 ttatcacgtg gaggtatagg atcgtttcca aaactatctt ttgattgtat ttgtccattc
    23161 tttttttgga caataaactc tgattgctgt tttttagaaa tctttttacc atactcaaca
    23221 gcatctgatt tattatcaaa tagttttgta tcttcggaat taccttcacc acgtacagcc
    23281 catttgccat ttctaggaga tacccattga tttttaccca taacaattca cctcgctttc
    23341 aagttaattc tattaagagg tgaaaagaaa acaaactgat ggaggtgaga ttgtgagtaa
    23401 caagccaaaa atcactttga atggcacacc taatcttcaa agattagcag atgaaatggc
    23461 tagaatacgt tctagacatt ggggagttac tgtggtggca accataattg aacaaaaaga
    23521 aaagcccaca cagccggcaa gcaagtagtg ggcaccatag aacaataata ttatatcaca
    23581 cactcgccac ttccgaaaag aggagttgct gctctccttt caagtttgcc aaagtccacg
    23641 tttcttcatt ttggcaactc ctcttcttgg aggtggtgac ggcgagagac gaaggaggga
    23701 tgacatgaag gaagaatcaa aaatagggat tttgaatgag aacaattaca caagattaat
    23761 tattgaaaca gaagaagggg aaaaagtagc agaagttaca ttgaccgatg caactcctgc
    23821 tgacggttat cgtattcgat taactcctaa atatgattaa ccttttggtg ggtgtggatc
    23881 gtttccggga ctatcacggc tttgaatttt tccatctctg ccatgaataa atagctcaga
    23941 tccttgattt ttagaaatct ctctagcgat ttttactgct tctgattttg tattagtatg
    24001 tgcagtcgct ttagaatttc cagcaccttt gacattccaa ccaccattgg aattaggtac
    24061 aacatgttga ttttttccca tagttttcac ctccatttct atagaaatat tttatcaaat
    24121 agaaatggag aaattcaata aacgaaagga gggatcaaat gacattacaa gagcatcaac
    24181 acttgatgcg aaaactaaat caggaatacc acgaggaaat gaaacctaga ttgctagggg
    24241 aacaatggcg tgaacgccag aagaagtggt tagaaataaa aaagtgactc agccgtccaa
    24301 agcaatgagt cacaaaccaa aaattatacc taaggagatt ttatcacatg aataagaaaa
    24361 ttgaaaatct tatcgaagaa ttgaaacgtg aatgccaaaa gcaaggtgtt tctattattt
    24421 gtacagccca aaaagaaggg gaacttaaaa gtctcgttta tggtgagaca acagaaattt
    24481 tactttgtct tgctatgcaa gaagaacatt tagatgaaaa tctcccattg tcagcacata
    24541 ttatgcgtag aattgctgtg gatgcttacg aacaagcgaa aaatgaagaa gaaaatcaac
    24601 cttcaaatca tacttttgtt attaataaca aggaagattt agctgatgtg atgactcgta
    24661 ttctcaaggg ggaatttcaa tgatgaatga aaaaacaatt gatctactca ttattttatt
    24721 tttcacgtta gtgattgtag cgaaaagtta tgtaatcttt ggcttgttat tcgcaattac
    24781 catgcttgtg ctttgcgtgt tagcaagcag aaaagaggtt aaacatgaac gagttagcaa
    24841 atcttgacaa ctatttaact gatcctgatt atgctaaacc accatatgaa gcgccaattg
    24901 atgaggagga tgaagatgag taaatctacc ttagaaatga gccatcaaga atggctcgaa
    24961 gaccgcaaaa gaggtattgg tggctcagat gttgcaaccg tacttggatt aaacaaatac
    25021 aaatctcctt atcaattgtg gcttgagaaa acgggtcaaa ttgaattgaa agatttagaa
    25081 agcgaaccag cttattgggg taatgtttta gaagaagtgg ttgctaaaga gtttcaggaa
    25141 cgtacaggca aaaaagtacg cagaagaaac caagtatttg aacatccatt acatccattt
    25201 ttaagagcaa atattgatcg ggaagtagtg ggagaaaatg ccattctgga atgtaaaaca
    25261 gccaatcaat ttctcggaaa agagtgggaa ggtgaagagg taccgcttag ctatctctgt
    25321 caagttcagc attacatgaa cgttttaaac aaagactatt gttatatcgc tgttttgatc
    25381 ggtggacaaa aattcatttg gaagcggatt gaacgagatc aagagctgat cgatacaatc
    25441 actgaacaat tagtagagtt ttgggaaacg aacgttcttg gaggtatcga gcctgtaatt
    25501 gacggaagtg gagcgactgc tgacttctta aaagaaaaat atgcagatgt agaagaaaat
    25561 caaacagctc taccatcacg ttttgatgaa cttatcgagc aaaaaagaga actcaaacgg
    25621 acgaaaaaag aaattgaatc agctatccgt caagtagaca acgagattat cagcgagcta
    25681 ggtaaacgtg aagccagtat cggtatcact caaaaaaaca tcatcagttg gaaatttgtc
    25741 cgtacgagac gtatgaactc gaagaaacta gcagagaaat atccagatgt cgcaaatgat
    25801 gaagagattt ataacgttac tgaatcaaga aggctaaccg aaaaggggat caaataatat
    25861 ggcaacaaat gaatcgttaa aaaatcaatt ggcagaaaag ccacagaaac aagttgcacc
    25921 aggacagtta gggcttaaag ctctaatgaa tacaccaaca atgagaaaga aatttgaaga
    25981 agtacttcat gacaatgcta atgcttttat gtcgaatgtt atgactcttg tatctaatga
    26041 cagttatctt gcagatagtg aaccgatgtc tatcatgagt ggtgcgttaa ctgctgcaac
    26101 attaaatctt gggctagata agaatttagg ttatgcatat ttagttccat tcaatagtaa
    26161 aaacaagcaa acaggaaaat gggaaaagaa agctcaattc atgcttggct ataaaggata
    26221 tatccaatta gcccaacgat caggtaaata caaagcatta aatgtgatcg aagtttacga
    26281 aggagaacta aaaagctgga accgactgac agaagagttt gagtttgatc caaatggtag
    26341 aacgtctgat gaagtcattg gatatgttgg ctatttcgag ttactgaatg gattcaaaaa
    26401 aactgtctat tggaccaaac aagaaatcga agctcatcgg attgctaaca ataaagatcg
    26461 cgataagaca aagttaagtg gtgtgtgggc atctgattac aatgcaatgg cacgaaaaac
    26521 tgttttgaga aatcttcttt ctaaatgggg aatcttgtcc atcgaaatgc aagaagccac
    26581 cacatcggat gagagagtcc aaagggttca agaagacggc agcattattg ctgaaacaga
    26641 agttgaagaa gatattcctg aaagaaaaga agcagaggtt atatctgaag aaaatgaaga
    26701 tgtacaaact ggattatttg atgcatctaa tccgccgtta aacaaataat gagggagctt
    26761 tctcccttgc ttttctagag gagaaatacg aatgaacaca ggatatgtca aattacatcg
    26821 aaaagtgatg aattcattcg tttggaccaa tccttatatg tataaattat ggagcttgtg
    26881 tttgatgaaa gcgagtcatg agaatcgcaa gatacttttt aatggaaaag agatacaagt
    26941 gaacagcgga gaattcgtca cagggcgcga tgctatcaca tctgagatga acgaaggcgt
    27001 gaaacgtgaa catcaagtga acagcggttc tgtatggaga tggctaaaac aatttgaaaa
    27061 aaacggaatg ttgaacatca aatcaactac gaaatacagc gttatatcaa taaaaaactg
    27121 gtctttgtac caaagcagtg aacaacaaat gaacatcaaa cgcacaacaa gtgaacaaca
    27181 agtgcacaca aacaagaatg aaaagaatta taagaatgaa aagaataata aaacatcatc
    27241 gtcgcaacca cgcaaaaagc gtgtttacga caccgactca gtttactaca ttctcgcgga
    27301 ggagttattc aaacagattt gtcagaatca ggaaatcaaa aagccgaatc tgcaaagttg
    27361 ggcagataac attcggaaaa tgatcgagat cgacaagcgg accgaaaacc aggtacgggg
    27421 aatgattgaa tggagtcagc acaatgtgtt ttgggcatcg aatattttat ctgctaaaaa
    27481 attgcgagaa aaatacgaca caatggcagc gcaagcaaat cgtgattata aaacaaaaca
    27541 aactaaaacg cttgaatacg agaaatttag cacagatgag ttgcctattt gagaggaggc
    27601 gtaggcatgg aaactgttgg ggaaatcatg gaaaagctga tacagaaagt gcttgtccaa
    27661 cgtggcgaat gtcctgaatg cggacagcct ttgtatggat ggcgtacgaa gaaccctgat
    27721 ggctcagaac gttgtaagcc aacctgtatg caatgtgggt ataaagcatt gcgagttcag
    27781 gaagacttac aaacagaacg aatttacaac gagagcctga aagcaagagc aatcaatttt
    27841 ttcaaaggtg gttctgttgt gcctaatcaa gcgttgtttg attgcacatt gcagaattat
    27901 caaattgtcg atcaagaaac aagacaagcg gttgaagtaa ccaaacgctt tgttaattca
    27961 gtcttgttag gaaatccaag tcaccttgtt ttaactggaa aacaaggaac aggtaaaagt
    28021 cacctagcga tggcagcggc ttgggaagtc ttgaagcgat caaactacga taaaaaaatc
    28081 ttatttatcg ggttacagga aatgctggat caaatcaaat tttcgtacaa caatcctgaa
    28141 ctcagaaaaa cgattgaggg atcgttgatt gcagatatca aaacagcgga tttagtcatc
    28201 attgatgata tcggttcaga actaggaaaa gatgcatcag atagtcgagc gtttggcata
    28261 aacacgctaa attcgttctt ggatgcacga cagaacctag caacgattat cacaacgaac
    28321 ttgcttggtg aagaactgaa aaaagcttac ggtacgagaa caatatcaag aatgtttgtc
    28381 aactctgatg gatttacgat ggtattttct caaacagcag acaagcgcat aaaaccagtg
    28441 aaaggtagta tcgcatgaat aaataccgta ataaaaaaac tgttcatcga ggtatcaagt
    28501 ttgattctat cgcggaagca gagtattacg atctagcctt gtggcaagct gaagcgaatg
    28561 gttggaaagt gaagctccag gaaaggtttg agctgatgcc gaagtttgaa ctagagggca
    28621 agaagtatcg caagatcgag tatattcccg acttcacatt ttacaaaagc ggcaagctgg
    28681 tcaaagtcgt agatgttaag gggatgcaga caaaagactt taagatcaag gcaaagttgt
    28741 tctgtcatca atatcaagtg ccgttgatat tagccaaaaa atatcggaat acgttcaagg
    28801 aagagcgttt ttaacgaggt ggtccatcat gacaacagaa gaagtgattc aaatgcgaat
    28861 tcgaagcctt cggcgtgaga ttgacgatct ggaacgaaca aaggcagtga tggtcaatga
    28921 aacggctaga aaggcaatcg atttgcacat agagaattta agaagggaaa tccgtagatt
    28981 ggaggaatga gcgtggataa ggaagcggct tggcgaaaat taatgttgct gattcaagat
    29041 gagaactggc aagaagatga agcagtggtt gctgaagttc agcgtctagg aaagattgct
    29101 aacggacgta tacgaaaaaa gccagacaaa agaaaacagc gcaaagggaa aatcgtcgtt
    29161 gttttacacg aaggcaaaat tttgatgcaa ggaacagcta gtgagctgtc tgcagaaact
    29221 ggatatacgc gtgggactat tcgaacgtac gcttggcgaa atcacaccga tcgaaaaggg
    29281 cacgaatata agtatttgga ggaagaaaaa tgaacgaaaa caaattaatc aaattgggtg
    29341 tagcaggagc agtaatcgta ggtattggag ttatcggagg atttaagttc ttcgaaaaaa
    29401 tcgataatgg atatgtgggt gtgcgctatt caatgaacgg cggtatcaaa gatgaagcac
    29461 tgacgcaagg tgtgaaattt gtagggattg acaaagtgat ccaatatcca attcgcttgc
    29521 aaactatcca atcaaaaaat atttcagtat ctacaagcga cggcaaaaag acaacgattg
    29581 atatcaaata tgactacaaa gttgattcaa ctaaagcagc aaaaatgtac aaggaatttg
    29641 ggaatatcac ttcggaagat atcgaaagtg gatggttaaa atctaagctt caaaaggtcg
    29701 ctcgtgaagt ttatgcgaaa tatagtctgc ttgatgtcct ttcaggagat tcctctaaag
    29761 ttgaagctga ggtattaacg aactttgcta aatcagttga atctaaaggg tttgaagtcg
    29821 aagacgtaac acttggtgtt ccagatgtcg ataaagaaac acaaaaatca atcgatgcga
    29881 tcattcgagc tggtcaagaa aatgaaaaag cgaagctaga cgcagaaact gcaaaaactc
    29941 aagctgatag tgaagcttac aagaaaacaa aagctgcaga agcagaggca gaatctaatc
    30001 gcaaagtcgc cgaatcagta acagacaatt tgattcgtta tgaagaagct caagctcgca
    30061 aaaagcatgg atgggtaaca gtaaatggag cagatactgt agttacggat gaagcaggca
    30121 aataatatgg gattctttat ggctaaaatt ctcttgttct taggtttagt aggagcagca
    30181 tatctcgtgt atgcgctcct ttcccaaact gatgacaaag aagatgacaa c
//
LOCUS       DAFEEZ010000034        29109 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000034
VERSION     DAFEEZ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29109
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.034"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..1030)
                     /locus_tag="LP245_001586"
     CDS             complement(<1..1030)
                     /locus_tag="LP245_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1519509.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="LP245_001587"
     CDS             complement(1112..1801)
                     /locus_tag="LP245_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL1519510.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="LP245_001588"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="LP245_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBL1519511.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="LP245_001589"
     CDS             complement(2328..2831)
                     /locus_tag="LP245_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBL1519512.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="LP245_001590"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="LP245_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBL1519513.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="LP245_001591"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="LP245_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBL1519514.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="LP245_001592"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="LP245_001592"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBL1519515.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="LP245_001593"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="LP245_001593"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBL1519516.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="LP245_001594"
     CDS             complement(6443..7462)
                     /locus_tag="LP245_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBL1519517.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="LP245_001595"
     CDS             complement(7635..8540)
                     /locus_tag="LP245_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL1519518.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="LP245_001596"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="LP245_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBL1519519.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="LP245_001597"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="LP245_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBL1519520.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="LP245_001598"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="LP245_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL1519521.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="LP245_001599"
     CDS             9753..10397
                     /locus_tag="LP245_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL1519522.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="LP245_001600"
     CDS             complement(10453..10956)
                     /locus_tag="LP245_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBL1519523.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="LP245_001601"
     CDS             11553..12518
                     /locus_tag="LP245_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBL1519524.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="LP245_001602"
     CDS             complement(12617..13789)
                     /locus_tag="LP245_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1519525.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="LP245_001603"
     CDS             complement(13776..14921)
                     /locus_tag="LP245_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1519526.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="LP245_001604"
     CDS             complement(14935..15867)
                     /locus_tag="LP245_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519527.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="LP245_001605"
     CDS             15984..17063
                     /locus_tag="LP245_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL1519528.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="LP245_001606"
     CDS             17060..17689
                     /locus_tag="LP245_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1519529.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="LP245_001607"
     CDS             complement(17799..18026)
                     /locus_tag="LP245_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1519530.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="LP245_001608"
     CDS             complement(18129..20717)
                     /locus_tag="LP245_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBL1519531.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="LP245_001609"
     CDS             complement(20737..21396)
                     /locus_tag="LP245_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL1519532.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="LP245_001610"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="LP245_001610"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBL1519533.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="LP245_001611"
     CDS             complement(22169..23035)
                     /locus_tag="LP245_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL1519534.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="LP245_001612"
     CDS             23144..23785
                     /locus_tag="LP245_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBL1519535.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="LP245_001613"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="LP245_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBL1519536.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="LP245_001614"
     CDS             complement(25226..26125)
                     /locus_tag="LP245_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL1519537.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="LP245_001615"
     CDS             complement(26127..26924)
                     /locus_tag="LP245_001615"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBL1519538.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="LP245_001616"
     CDS             complement(26902..27606)
                     /locus_tag="LP245_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBL1519539.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="LP245_001617"
     CDS             27737..28312
                     /locus_tag="LP245_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBL1519540.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..29107
                     /locus_tag="LP245_001618"
     CDS             28430..29107
                     /locus_tag="LP245_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBL1519541.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8564 a         6169 c         5232 g         9144 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gcttatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taattaaaa
//
LOCUS       DAFEEZ010000035        28829 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000035
VERSION     DAFEEZ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.035"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(44..682)
                     /gene="plsY"
                     /locus_tag="LP245_001619"
     CDS             complement(44..682)
                     /gene="plsY"
                     /locus_tag="LP245_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBL1519542.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            809..1243
                     /locus_tag="LP245_001620"
     CDS             809..1243
                     /locus_tag="LP245_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBL1519543.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            1409..3454
                     /gene="parE"
                     /locus_tag="LP245_001621"
     CDS             1409..3454
                     /gene="parE"
                     /locus_tag="LP245_001621"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBL1519544.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            3466..5916
                     /gene="parC"
                     /locus_tag="LP245_001622"
     CDS             3466..5916
                     /gene="parC"
                     /locus_tag="LP245_001622"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBL1519545.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            6193..8424
                     /gene="pflB"
                     /locus_tag="LP245_001623"
     CDS             6193..8424
                     /gene="pflB"
                     /locus_tag="LP245_001623"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBL1519546.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            8668..9429
                     /gene="pflA"
                     /locus_tag="LP245_001624"
     CDS             8668..9429
                     /gene="pflA"
                     /locus_tag="LP245_001624"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBL1519547.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            9514..10440
                     /locus_tag="LP245_001625"
     CDS             9514..10440
                     /locus_tag="LP245_001625"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBL1519548.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            10622..11515
                     /locus_tag="LP245_001626"
     CDS             10622..11515
                     /locus_tag="LP245_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBL1519549.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            11649..11774
                     /locus_tag="LP245_001627"
     CDS             11649..11774
                     /locus_tag="LP245_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1519550.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(11908..12540)
                     /locus_tag="LP245_001628"
     CDS             complement(11908..12540)
                     /locus_tag="LP245_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519551.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(12688..13230)
                     /locus_tag="LP245_001629"
     CDS             complement(12688..13230)
                     /locus_tag="LP245_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBL1519552.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13365..13754
                     /locus_tag="LP245_001630"
     CDS             13365..13754
                     /locus_tag="LP245_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519553.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            13758..14522
                     /locus_tag="LP245_001631"
     CDS             13758..14522
                     /locus_tag="LP245_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL1519554.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            14651..15598
                     /locus_tag="LP245_001632"
     CDS             14651..15598
                     /locus_tag="LP245_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1519555.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            15728..16468
                     /locus_tag="LP245_001633"
     CDS             15728..16468
                     /locus_tag="LP245_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519556.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(16759..17427)
                     /locus_tag="LP245_001634"
     CDS             complement(16759..17427)
                     /locus_tag="LP245_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1519557.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            17561..17848
                     /locus_tag="LP245_001635"
     CDS             17561..17848
                     /locus_tag="LP245_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519558.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            18264..19802
                     /locus_tag="LP245_001636"
     CDS             18264..19802
                     /locus_tag="LP245_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBL1519559.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            19799..20764
                     /locus_tag="LP245_001637"
     CDS             19799..20764
                     /locus_tag="LP245_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519560.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            20751..22073
                     /locus_tag="LP245_001638"
     CDS             20751..22073
                     /locus_tag="LP245_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1519561.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      22136..22240
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22314..23057
                     /locus_tag="LP245_001639"
     CDS             22314..23057
                     /locus_tag="LP245_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1519562.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            23072..24064
                     /locus_tag="LP245_001640"
     CDS             23072..24064
                     /locus_tag="LP245_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL1519563.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            24076..24813
                     /locus_tag="LP245_001641"
     CDS             24076..24813
                     /locus_tag="LP245_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519564.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            24803..25525
                     /locus_tag="LP245_001642"
     CDS             24803..25525
                     /locus_tag="LP245_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBL1519565.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(25609..26232)
                     /locus_tag="LP245_001643"
     CDS             complement(25609..26232)
                     /locus_tag="LP245_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1519566.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            26627..27318
                     /locus_tag="LP245_001644"
                     /pseudo
     CDS             26627..27318
                     /locus_tag="LP245_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
     gene            27526..27816
                     /locus_tag="LP245_001645"
     CDS             27526..27816
                     /locus_tag="LP245_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519567.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT        10005 a         4824 c         5950 g         8050 t
ORIGIN      
        1 gatttgtcac actcccgttt tatctctttg gaatgaaaaa gtatcaggat tttttcttgc
       61 tgctattcaa accaaacggg attcgacttt cagtatggtt tctgatacgc ttgatattgt
      121 ctttatgccg ataaaagata aaggaagaaa ctaaaaaggc aatgatcgtc agtaaccaat
      181 tgggcttagc caaaatcaca ggagctacat aaggaaggac gatcgtagat aaagtgatca
      241 atactgcact gatcatactg ctcaaactca ccatacttgt acaaaataaa ctaacgataa
      301 agatgataca agaataaaca aaaaatacag gattaaatcc taaaagcatt cctgcacttg
      361 tcgcaacagc ttttcctcct ttgaacccag caaaaatcgg aaatgtatgg ccaagaatgg
      421 cgcatacccc aaaccaaaga gggttaatcc cagaaaggtg gaagatcatc ggcaaacaag
      481 tagccaatgt accttttaaa atatccataa gcaggacaac aatcccggct gttttgccta
      541 atacacgaaa tgtattggtc gttccagtat taccgctccc gtgttgtcgg atatcttttt
      601 tgaaaaacaa tttgccaatc cagacaccgg aaggaataga acctaaaaga tatgctaaaa
      661 taagtaataa gatcaatttc attttttacc ctctttcaag ttgaaaacta tcctttattt
      721 tagcatgaat aggtaacagg aacaattgaa aaaatgaaag atacaagtat aatagatgga
      781 ataaaaagaa aagcaagggg tggcagaaat gtctgtaaaa aatccaacac aagaaacgat
      841 tttcaactat ttggaagaag caaaaaatat tgccgtcgta ggcttgagca ataaaccaga
      901 acgaacaagt tacatggttg cacaggtatt gcaagacaat ggatataaaa tcataccagt
      961 aaatccatta ttggctggtg aagaaattct aggcgagaaa gtctatgcga atttgacaga
     1021 aatcgatgat ccaatcgata tcgtagatgt atttagacgg agtgaatttt tacctgaaat
     1081 agcaggtgat tttttgaaaa ctgatgctaa agtgttctgg gcacaattag ggattgaaaa
     1141 caaagaagca gctgagatgc taagaaaagc aggacgtaca gatatcgtaa tggatcgttg
     1201 tattaagatt gaacttggta agttgaaaga aaaccaaaaa taaaaatgac cacaaagaag
     1261 agatgatcga tagaggggaa tgtcgaaaaa gcggttagga gataattaaa attgatttct
     1321 cgtctaccct cttttttttc acgacctttt ctagtatgat aatcgtggtg cggttttgcc
     1381 gcaaagtatt attgaaggag cgtttgcctt ggcaaaaaaa gtaaacaacg aatacaatga
     1441 ctcgtccatc caagtattgg aaggattaga ggcagttaga aaaagaccag ggatgtacat
     1501 tggatccact gacagccgag gcttgcatca tttagtctat gaaatcgtcg ataatgcagt
     1561 tgacgaagca ttatcaggtt atggcagtga gattgatgtg accatccatg aagacaatag
     1621 tataactgtt gcagatagcg gacgtgggat gcctgtagga atgcatgctt ccggaatacc
     1681 aacagttgaa gtgattttta ctgtgctgca tgctggcgga aagtttggtc aaggagggta
     1741 caaaacttct ggtggactgc acggtgtagg agccagtgtg gtaaatgcct tatcgaaatg
     1801 gctaattgta acgatcgtta gagatggcgt agagtatcag cagaaattta aaaacggcgg
     1861 taaacctgac ggtactttga aaaagatagg aaaaacaaaa aaagcaaacg ggacgactgt
     1921 ccatttttta ccagatgata caatattcag tacaacgaaa ttttcatatg aaattttagc
     1981 cgaacggtta agagaatctg cctttcttct aaaaggcgtt aaaatctctc tttctgatct
     2041 tcgtggagaa gaaccagtca aggaaatttt tcattacgaa gaaggaatca aagaatttgt
     2101 tgattatctg aatgaagaaa aagatacatt gacaccagtt gtttattttt caggagaaaa
     2161 agaaggtatc gaagtagagg tcgcttatca atacaatgac ggttattcag aaaatgtttt
     2221 atcttttgtc aataacgttc ggacaaaaga tgggggaacc catgaagctg gtatgaaagc
     2281 ggcgatgacg aaatcttata atgaatatgc gagaaaagtt ggtttgctga aagaacggga
     2341 caagaatctg gaaggtagtg atttcagaga agggttagct gctgtacttt ctatccgtgt
     2401 acctgaaaat cttctgcaat ttgaagggca aacaaaagaa aaacttggta cgccagttgc
     2461 tcgtaccgta gtagataacg tcatcagtga acaaatgggc ttttatttgc aggaaaatag
     2521 cgaaatgagc cagatgttgg tccgtaaagc aatcaaagcc agagaagcga gagaagcagc
     2581 acgtaaagcc agagaagaaa gccgaaatgg gaagaagcgt aaaaaaggcg aatctcttct
     2641 ttcaggaaaa ttgacacccg cacaatcccg aaaccctaag aaaaatgaat tgtatttagt
     2701 cgaaggggat tctgctggcg gatctgctaa acaaggaaga gacagaaagt tccaagcaat
     2761 tctaccttta cgaggaaaag tcatcaatac cgaaaaagct aaaatgcaag atatcttgaa
     2821 aaatgaagaa atcaatacga tgatctatac gattggtgca ggagtcggtc ctgagttttc
     2881 tatcgaagac tgtaattacg acaaagtaat catcatgacc gatgcggata cagacggcgc
     2941 ccatattcaa gtattactgc ttactttctt ttatcgttat atgaaaccgc tgattgaagc
     3001 tgggaaagta tatatcgcgt taccgccttt atataaagta tccaaaggac aaggaaagaa
     3061 gcaagtcatt gaatatgcgt ggacagatga cgaattggca gcaatgatta aaaaagtcgg
     3121 caaaggatat atgctgcagc gatataaagg acttggagag atgaatgcgg aacaattgtg
     3181 ggaaacaacg atggatccga cttcccgtac gttgatccgc gtccgtatcg atgatgctgc
     3241 gcaagctgaa cgtcgagtaa ccacactgat gggtgacaaa gtagaacctc gaagaaaatg
     3301 gatcgaaaat cacgtgcaat ttacgctcga agaagatggc agtatcttag ataaaaaaga
     3361 ggatactgaa atctctcctt cagtttctaa tgatttatta gatgaagaac gagcagataa
     3421 aaatgaaaac aatcagttat ttgaagtaga ataggaggtc acctgatgga aaatcgacaa
     3481 gaagtacaag aattaacttt agaagaagtg atgggtgacc gcttcggacg ttattccaaa
     3541 tatattatcc aagaacgtgc actgcctgat atccgtgatg gattgaagcc agtgcaacgc
     3601 cggatattat ttgccatgaa caaagatggc aatacgtatg acaaaggatt ccgtaaatca
     3661 gcaaaatctg tcggaaatat catggggaat tatcatcctc atggtgaccg cagtatttat
     3721 gaagcgatgg tccgcatgag ccaagactgg aagttgcggg aagtactgat cgaaatgcac
     3781 gggaataacg ggagtatgga cggtgatcca cctgctgcga tgcgttatac tgaagccaga
     3841 ttatccaagt taagtggaga gatgctagca gatatcgaga aagaaacagt cgatctcgtg
     3901 tggaattttg atgatacaga aaaagaacca acagtccttc cagctcgata cccaaacctt
     3961 ctcgtcaatg gatcgacagg tatatctgct ggatatgcaa cagaaatccc gactcataac
     4021 ttagctgaag tgatcgatgg cacaatctat atgatcgatc atccacaagc gagccttgaa
     4081 aaattgatgg aatatattcc tggacctgac tttccaacag gagggatctt gcaaggaaaa
     4141 gatgaaatca aaaaagctta tgaaacagga cgaggaaaag ttattcttcg ttcgaaaaca
     4201 aagatagagg caatgaaggg taataaacag caaatcgtga tcacagaaat cccatatgaa
     4261 gtaaataaag cgaccttggt gaaaaaaatg gatgagatcc gtttgaataa gaaaatcgat
     4321 ggaatagctg aagtacgaga tgaaagtgat agaacaggtc tgcaaattgt cgtcgaattg
     4381 aaaaaagacg ccaatgctca aggaattttg aattatttgt tcaaaaacac tgagctacag
     4441 atcaattaca atttcaatat ggtcgctatc gaccatatga ctccgcatca agttggactg
     4501 aaagacattt taagaagtta tatcgagcat cgaaagcaag tcataacaaa acgtagtcaa
     4561 ttcgatttag ccaaagctca aaaaagacag catatcgtag aaggattgat gaaagcttta
     4621 tcgattctgg atgaagtaat cgcaacgatt cgtgaaagta aagacaaaaa agacgccaaa
     4681 aagaatttag tcgacgtctt tcaatttaca gaagaacaag cagaagcaat tgtcacattg
     4741 caattatacc gtttgacgaa cacggatatc acagagcttc aaaaggaatc cgaaagcttg
     4801 attgcgcaaa tcacagagtt gaataaaatc ctttcaaatg acaaagagct tttctctgtt
     4861 atgaaaaaag aattgcgaga agtgaaaaaa aattattctt ccgctcgtct aacgacaatc
     4921 gaagacgaaa tcgaagaaat caaaattgat acgcaagtct tagtggcaca agaagacgta
     4981 attgtcagtg tgacgcgaga aggctatgtg aagcgaacaa gccttcgttc ttatagtgct
     5041 tccaaaccag aagaaatcgg gatgcgagaa ggcgactact tgctatactc aggtgaattg
     5101 agtacattgg accatgttct tctgatcaca aataaagcaa atgtgatcta ccgccctgtc
     5161 catgaactac ccgatttgaa atggaaagat gctggtgagc acatttctca aacaatctcc
     5221 aatctgtctg tagacgaatc gattttagct gttttcccat atcaaaaaat tcaagcagag
     5281 aaaacatttg tattcatcag caagaatgga ttgatcaagc aaacacgaat gacagagttc
     5341 gaaccatggc gcacctataa gagccgtccg ctcagctgta tgaagctaaa ggcggaagaa
     5401 gatgaactga ttgctgtgta tctgaaagaa gatcagccag gcttagatgt tttcttagta
     5461 acgcatcaag gaatgggttt gcgctatcct ttaacagatg ttcccgttgt tggagcaaag
     5521 gcagctggag tgaagtctat gaatttgaaa gatggagata ggattatcaa cgggctgctt
     5581 gtgttagcag aaggtgatac gccgatcgta atcgttactc agcgaggagc tgttaaacgc
     5641 atgcttgctc aagaaatcag ccaaacttca cgtgcgaagc ggggagtgac ggtcatgcgt
     5701 gagctgaaaa aaaatccgca ccgtattatc tatatgtcgg aaggaagatc aaaagaaata
     5761 accttgatga atcaaaaagg gcagcagtta acgattgacc caactgattt ccctataggt
     5821 gatcgaacat cgaatggatc atttgcgatg gatgagaaaa aaggtggaga agtcatcgaa
     5881 gttatcgatg ctcctgagat tttcatcgag tcgtaactgt tgtagtattt taatgaagag
     5941 acgccatctg tattaataca ggtggcgtct ctttttcatt catttttaat aaatccttat
     6001 acgtttgcaa aaaaagatga aagtgttcac aatgcttaaa tgttggtatg tcaacgttga
     6061 tttaaatata tgtaaataaa acataaaaat tgttaaataa aaaacaagaa aacccttgca
     6121 aagatagggt gctgtgttat actaatcacg taaaaactgt tacataaaac agaaatttag
     6181 gaggtccata caatggagca atggaatgga tttaaaggta ccaaatggaa agaaggcgta
     6241 gacactagag actttattca aaataactac actgaatatc gcggtgatga cagctttttg
     6301 gaaggcccaa cagaagcaac agaaaaatta tgggatgaat tgcaaaagtt aaatgatatc
     6361 caattcgagc gtaacggtgt ctatgatatg gacacagaaa tcgtatcaac tattacttca
     6421 cacgatgcag gctatttgga taaagatttg gaaaaaatcg tcggtctaca gacagacaaa
     6481 cctttgaaac aagcattcat gccgttcggc ggaatcaata tggctaacaa tgcgctaaaa
     6541 agcaatggct atacaccaaa cgatgaattg acacatattt tcactgactg gcgcaaaaca
     6601 cataatcaag gtgtatttga cgcttatact gctgaaatgc gtgctgctcg taaaaacaaa
     6661 atcattacag ggcttccaga cgcttacggt cgcggacgta tcatcggtga ctatcgtcgt
     6721 gtggcattgt atggaatcga ctatttgatg gaacaaaaga aaaaagatca tgatatgact
     6781 ggttatcata caatgagtga agaagtgatt cgtttacgtg aagaaatcac tgaacaatat
     6841 cgtgcattag cgcaaatgaa agaaatggct gcgaaatatg gctatgatat ttctaaacca
     6901 gctgcaaatg caaaagaagc tgtccaatgg ctatacttcg gatatttagc agcaatcaaa
     6961 tcacaaaatg gtgctgcgat gtcaatcgga cgtatctcag cattccttga tatctatatc
     7021 caacgtgatt tggataatgg agtaatcaca gaaaaagaag cacaagaatt gatcgaccac
     7081 ttagtaatga aattacgtat ggtcaaattc gcgcgtacac ctgaatataa ccaattattc
     7141 tcaggattcc ctatctgggc tactttatcc attgcaggta tgggattaga tggtcgttca
     7201 ttagttacaa agaatgattt ccgtctgctt catacattaa caaatatggg accttcacca
     7261 gaaccaaact tgactgtttt gtattctgaa caccttccag aaggattcag aacatatgct
     7321 agcagaatcg ctatcgaaag ttcttcgatt caattcgaaa atgataatca gcttcgtgaa
     7381 caatggggtt ctgatgattg tgcgattgct tgctgtgtat caggaacagt tgtcggaaaa
     7441 gacatgcaat tctttggcgc tcgtgctaac ttggctaaaa cactattata tgccatcaat
     7501 ggcggagtcg atgaagtgac tggcgcccaa gttggaccag aatatcgtcc aatcacatca
     7561 gaaatactag actttgaaga agtgaaacat aacttcatga atatgatgga ttggttagca
     7621 gaactatatg tcaatacgtt gaacatcatt cattatatgc atgataaata ttcttatgaa
     7681 gcagctcagc tggctttgat ggattctgac ttgcaacgca catttgctac aggtattgct
     7741 gggatctctc atgcggcaga cagcttgtca gcgatcaaat atgcaaaagt aaaagcaatc
     7801 cgtaatgaaa aaggaatagc agttgatttt gaagtggatg gcgacttccc taaatacgga
     7861 aatgatgatg accgtgcaga tgaattagtt tcatggatct tggaatactt catgggacaa
     7921 atcaaacgtc ataaaactta ccgcaactca aaaccaacaa cttcattatt gacgattact
     7981 tcaaatgttg tttacggtaa aaatacagga aatactcctg atggccgtga agctggaaaa
     8041 ccacttgcgc caggagcaaa tccaagttac aatgcggaac aaagtgggtt attagctagc
     8101 ctgaactcaa cagctaaaat gaattacggc tgtgcattgg atggaatttc aaatacccaa
     8161 acaatcaatc cttcaggtct tggaaaagaa caagatacaa gaatcgaaaa cttgcgtaat
     8221 gtcttagatg gatacttctc aaaaggagct tatcatttga atgtcaatgt attcagtaat
     8281 gatttattgc gtgatgcaat ggaaaatcca atgaaatatc cgaacttgac gatccgggta
     8341 tctggttatg cagttaaatt ccgtgacttg acaagagaac aacaattaga tgtcttgatg
     8401 agaacttcac acgacagaat gtaaaaagtt cgtgaaaaaa gtttttcgac ttagcgtcga
     8461 aaggacgttg aatagccatc gcatcaaaat cgaataatca gtatgcttat ttgaaagaaa
     8521 cgatttacag gggcaggact tgtatgttcc gtccctgtaa attttacaca taacgaagcg
     8581 gcaattgcga aaaattttgt tcagaaagct tcgcttcgac agctaacttg tacttaaaat
     8641 gaaatcaaag aaaagatgtg aacttaaatg gaagaaaaaa caatcggcta tgttcattct
     8701 atcgaaactt tcggttcagt agacggacct ggactgcgct ttgtcgtgtt tatgcaagga
     8761 tgccgcatgc gttgccaatt ttgtcacaat ccagatactt ggaatattgg cggagggaaa
     8821 gaatacacag cagatgaact tttagataaa gcagaacgct tcagacctta ctggggagat
     8881 aaaggtggta ttactgttag tggtggagaa cctctattgc agatcgattt tttgatcgaa
     8941 ctatttaaaa aagcaaaaga gcggaagatg catactacat tggatacatg cggaaaacct
     9001 tttacgtatg aagaaccttt cttttcacgt tttcaagaat tgatgaagta tacagattta
     9061 ctgttatttg acatcaaaca catcgataat gaagagcata aaaaactaac gcattgggac
     9121 aatgaaaata ttttagaaat ggctcaatat ttgtcaaaaa tcaacaaacc ggtttggatt
     9181 cgccatgtac tagttcctga gcgaagtgat tatgatgaat atttgatccg actagacaac
     9241 tttattcaaa ccttgtcaaa tgtagacaga gtagagattc ttccttatca tacgatggga
     9301 aaatacaagt gggaaacact tggtttgaaa tatccattag aagggatcga accacctaca
     9361 aaagaacgtg tcgaaaatgc taaacgattg cttcatacag aagagtatac aaaatattta
     9421 acgcgatagg tcgcatcgga aagaagataa gtattgcttc tttccgtttt tttgctatta
     9481 ttaaatagga gaaatcacaa aggagcgaat gacatgtcaa aaattttagt ttttggtcac
     9541 caaaatccag atacagatgc aatcggggca gccattgcgt tttcacactt gcaaaatgaa
     9601 ttaggtaaag aaacagaagc agttgctcta ggtacaccta atgaagaaac acaatacgca
     9661 ttagaccact ttcagctatc tgcaccacga gtagtagagt cagctaaagc agaaaatgca
     9721 gatgtcatgc ttgtggatca taatgaattc caacaaagta tttcagatat cagcgaagta
     9781 aatattttag ctgtagtaga ccaccatcgt attgcaaact ttgaaacagc taatccattg
     9841 tactatcgtg cagaaccagt tggatgtaca agtacgatta ttttaaaact atataaagaa
     9901 aaccaagtaa caattcctaa agaaatcgca ggaatcatgc tctcagctat catttcagat
     9961 acattgttgt tcaaatcacc aacatgtacg cctgaagatg aagcagctgc aaaagaactt
    10021 gcagcaatcg ctgaagtcga tctaaacact tatggacttg aaatgttgaa agcaggaaca
    10081 aatctaagtg ataaatcagc tgcggttctt cttgatttgg atgcaaaaag tttcccaatg
    10141 ggcagttcca acgttcgtat cgctcaagtc aatacagtgg accttaatga agtgatggat
    10201 cgacaagcag agctagaagc agcaatggaa gatgaaatga aagcaaatgg ctacgatctg
    10261 ttcgtattag ttgtcacaaa catcttagac agtgattcag aattacttgt tgctggtaaa
    10321 ggaaaagaaa aagtagaaga agctttccaa acaactttga ccaacaaccg tgctttgctt
    10381 aaaggtgtcg tttcacgtaa aaaacaagtc gtacctcaat tgacggctgt atttagctaa
    10441 tcaaatggta gtatgaagca ttcaaaatga atggataagc gattgatata aaaagaaaca
    10501 tagaacatac taaaggccga agaaatggag gagaataaca gtcaattatg actcttgttc
    10561 ttcctccttt ttacgtaaaa gccttttaag taaaataaaa cggatagaaa agagaacata
    10621 tatgaactat tattcaaaaa ataaggaaaa cttttatcaa aaactgaccg atgatccgct
    10681 tttttcttca ttgaccgatt atctatatga acatcgagaa caagaaacga ttctaagaga
    10741 attgaaaaaa gaattttcgc aaaataaatt ttcccatttt cttgatttat tgatcgatgc
    10801 aggattaatc aagagggaag aacgaagata tcatttgaac tttccaatat ttgatcctaa
    10861 agattacttg caacaagcca cttcggctgc tgaaaccata gctgaacaat tgaagagact
    10921 ctctgttgat gaacaaaaat tagcgatggg agaagttatt tgggcgtatt gtttcgaaga
    10981 tgaacggaaa gaagcgtatt tttatggagt aagaaacagc cgagagacag aattgctgag
    11041 gacaactgca ggaaatgaga agtaccgttt tatcacactt tcctctatag aacacttccc
    11101 gcttactttg gctaattact tttttgtaca gaagaatcag cttcctgtaa cgaaggcatt
    11161 caaagaatta gccgaactta ttggagacgt aaatgaatcg tacttttttg atcaaataga
    11221 agttatcgtt gacaggatac gtaagaataa atataaaaat cgccggccta gtattttcca
    11281 tcagtctcta cttgtgacga atactataaa ggaagaagaa tcattcacat tagaattacc
    11341 tattgtcgaa aaaaacaatt ttgagattga attaccaaca ttggatcctt cattgacaat
    11401 ggaggaaatg gcctttctta aacgacaaat cttttctgag ctgagcaaga aatttatacc
    11461 gcatgcattt tcttatatca aagaatatgg aacagtttta gtgagtaaaa cctaagagag
    11521 cagtaagcaa aaattatact gactcttgca ggaggagcct ttctcttcct ttatggttaa
    11581 aagaattatt tgagtatttt gcctatctac cacctattag attcactaca tggtctggaa
    11641 acaaaggaat gcaaaaaaat ggtgagaaat gtggaatgac aaaggaagta gtgataagaa
    11701 aagttagatt tttaaataat caatattatg attcagtcaa gtatggcatt ttatgggaag
    11761 aactagctga ttagattagg aagtccattt gataatccag aatcactaag aaacgaatgg
    11821 cgagtcatta ataatttatc caatcttggg ttattctttt agattgaagt gtttaaaact
    11881 aaaaaagcat ttatgaagtc gtaatagtca ggcttcaaaa tgctttttat tttgtttgtt
    11941 ttttctttgc cacataaata cacctagact gacgatgaag agcatatcca acagatttcc
    12001 tgcgacttgg atcgtcgaag ggttggtcag tggcattaaa gcaaggacaa aaaaggaaaa
    12061 caagctgtaa ataaaacagg tgacaggaac taatcgaaag aagagcggac atttcaattg
    12121 gctaaaaatg agtgaaaaaa taaaataagt aaaaatggat aaaatcacga ctaaaccatt
    12181 catgataaag aagaaaagcg tattgtgatt aaacgaataa aaaagaattg ctaaaaaaga
    12241 aaacgtttta aatgcaatca atacgcttga agcttcgttt aacgtaccag gatgtcgatg
    12301 aaaaaaatag gcaccgaaat aaacagaaaa cagtaagccg caaagagaag acaaaatcaa
    12361 aaaaaacgga ttttcttcgg cttctgtgat atcagaatga tccaaaagca accagcctaa
    12421 tgcactagaa ggcgcatgtg aggtcttaag gtatgaataa catagaaaaa ataagatcgt
    12481 caaagttgca aaaaaagagc ctaaatgtaa aaaattagtg gttctacgtt gaatttccat
    12541 aatatctcca aattaaattg ataagtatat aaagtataat aacaaattga tgagtatatg
    12601 tcgatgtttt ttaatcaaaa taataaataa aaactgtcta acatttaaaa tttaatttag
    12661 atattagaca gtttttaagt ttgtgagtta ttttccttgt cgttttctca cttttttagt
    12721 ccagaaacca cctgaaatat attttggctc ataagaaatg ataaaagcac gctcttcgat
    12781 ttctttgatc aggcgataca gttcacgttc gctttttcta ggagaaagta tttcgagaac
    12841 tagccgctca ccttccagcc ccattgcaga agtctgtgtc acaccataac cgtgttctct
    12901 cagtataccc ggcaaacttt tatcttctgc gctatttgct ggcaaaatcg ttgtgaccat
    12961 gatgtatcct aatgccaatt tgtcttcaat caaaattccg acactgatac ctactgcgta
    13021 acctaacgca tagacaaata aattcagtgg attatctaaa cgatctaaaa caagggataa
    13081 gccgacgata taaatcgtga tctcgaccat actgacaagt ggagcaatca gtcgatagcc
    13141 tttcattgtc aacatgaaac gtaacgtgtt cagagtgata taagcaaaat taatgaggaa
    13201 gatcatcccc aacatttttg gatcaatcat ttgtaaaact cctttcattt atataacaac
    13261 aatatcaaaa aaaatcgtaa gtgaagaaaa attgaaactt tatacataca aaaaaatgat
    13321 aaaatgatta taatagaatt ataaagatag gttaggtgat taaaatgaaa acggtcaatc
    13381 gtgtgttttg tgccagccac gtgctaagtc tccttctcag tatatactta ggtgtctatt
    13441 cgattcaaca gccaattgag gtagagaaca ttgtttttca gatgtcgctg acagatggtt
    13501 taattttaag cgtttttttc tttttgatac tgtttattgg taatattttc ggtagcgttg
    13561 ccagtttttt gaatttttct atttatccac tcctttcgct agcattagga gtggtgggac
    13621 tttgttctct gtgcttattt cccgagccat tcagtcctgc atttatatta tttggtacac
    13681 tgaacctgtt ccagacaact gttggagcat ggttgctatg gcgatcagga aatttaatga
    13741 aaataggtga gtaacaattg aatccaatta tattgaaacg ttctgtccat catattccag
    13801 tgttagaagt tgttctgaaa gaattaagag aggaacgtat tcccgttgtc atctattatc
    13861 acggatggca gacaagtaag gagttagttt tgacgcaagg aagaaaaatt gcgcagcagg
    13921 gcattcgtgt gatcctgcca gatgcgatga atcatgggga gcgcaaacag ccggtttctt
    13981 ctattccatc ctatacattt tgggatagta tctacggaaa tctgtttgaa tttgacacac
    14041 ttatcaagca tttagaaaaa agaggtcttc tacatgatca gcttgcagtt ggcggggttt
    14101 cgatgggggg aatgacaaca tgcgccttgt tggctaaaca tcctcatata gtagcgggcg
    14161 tgtgtttgat gggttcccct gcacctttgg aatatggaaa agaaatcgta aggcgcgcat
    14221 cggaatataa ttatgtcgta ccaaaagact attttgattt gatttcatgg gttaagagct
    14281 atgatttgtc attgcagccg gaaaagttag ctggacgtcc tctgttcttt tggcatggac
    14341 aagctgacga aaaaatccct tatatacaaa cggaacgatt tgtagaaaaa aatcggcata
    14401 agtcttacgg aaaagaaatt gtttttcgtt cctcaaaaac acagcgacat atggtacaaa
    14461 taccactaat ggaagaagct tccacttttt tagcaaaaaa tttgataaaa aagtataaat
    14521 aattgaaacg gaaaatcact catgacgata gaggattttc cgttttttat tttgggctat
    14581 aataaactct gttaggaaaa tttggtataa ttgatagtaa gaatgacaac atgttagaaa
    14641 ggaagagagc atgcccactt tagcagatgt tgcaaaacgt gccaatgttt caaaaatgac
    14701 ggtctctcga gtcatcaatc atccggaaca ggtgactgac gaattgaaag agttagtttt
    14761 ctcagcaatg gctgaactgg attaccgtcc aaatattgct gcaaaagcac ttgtcacgaa
    14821 tcggtcgcag atcatcaaat tatttatact ggaagaaatc gacacaactg agccctatta
    14881 catgaatttg ctgatgggaa tcgctaaacg gatcggtaaa gcgcattatt ctctccaatt
    14941 agttacaaat gatgccttcg acgtcggttc ttgtgatgga tacatcatca caggtgtcag
    15001 aaaaaaagac ttcgattgga tcgaccgttt ggaaaaacca gttgtcttgt ttggggaaaa
    15061 ttctgaagga tatgattatg tagacagcga taatgaatat ggtacagcaa aagcaacgca
    15121 atatgcctta gaaagagatt atcaaacgat tatttatatc ggtatcgaag tggacgagcc
    15181 ttttgaaatt tcaagggaaa ctggttattt atctgtgatg aaggaagttg atcttcctag
    15241 taaaatcttg cggtttccaa atcattcgac agaagtagaa agatatatga cagaaaactg
    15301 ggcagatttt acagataaaa cttgttttgt atgtagttca gatcggctag cactaggagc
    15361 agtaagaggg attataaatg ctggaggaca cttgcccgaa gaatttggtg tgattggatt
    15421 tgatggggta tttttagacc aaatcagttc acctaaattg acaacgatca agcaagatat
    15481 tatacgtatg ggtgaagtat gtggagaaat gttgttaaaa aaaatagaag aaaaaggggc
    15541 gagtcaaggt tatcgtcgtt tttttcctga actagttatc agagagacaa cgaattaagt
    15601 cttattacta tatatatatt tatgaaattc atcgctattt tcttaaaata atcagcgcat
    15661 tgctactgaa aacaatgaat ctgtgctatt attgagaaaa gttccatttt tgagaaggat
    15721 ggtttgaatg aaagaaatca gacgaaaaca tttccgtttt cctgcgtacg atgatgagtt
    15781 aggcgtaaaa ttaaccaacg acaagaagcg agtattattt gacggacaag aagatctttt
    15841 gactgaacag aatcagtccc cgtttgaaca gatgaaagaa tttcatttca cgaacacgaa
    15901 caccgagaaa atccgtcgca agcgtcgtgc aacaaatgga ttgaagtcag ctccgcgtaa
    15961 ggaaaatttg gaaaagcata aaggaaaatt accggattat accggccatt accaatcaga
    16021 aatcacatcg acaggacgaa aaaaactttt tggtgattcc tctcgttctg tcagacaaag
    16081 tgaaacaagg acagagtcca agcatactac acgaaacgca tctgttgaca cgaaggtgcg
    16141 ggagcgttct tattttgttc ctaaatatgt acccgcatcg attatcccag accctagaga
    16201 aagcaaaatt tctgaggatc atttaatcga atcgatgaaa aaaacggatg actcttatct
    16261 gttgttcgat acagaaccga cgccgtatca agaaaaaaga aatggtgagc cgtctgtacg
    16321 aacattcaat cgaacaaaaa cgttagagga aacaaagcag tcagaagaaa aaaaatcgaa
    16381 aaaaagccat ggtatcttag aacgctcatt acaaggattg atcgatgatc aaggaaactc
    16441 tttgggagaa aatagctatt ttaaataagt gatatacaaa tttatattcg gctacagttg
    16501 gaaaggaaac gctgcggcgt ttccttattt tatactctat ccgaaagttt atatcgtatc
    16561 ctcaaatttt tttgagttta agcgaatttt ttctcccaat aagtaagaaa ataatggcaa
    16621 aataaaaaaa caaactattt tcgcagatcg tttgcaaaaa tagtttattt ttttataaag
    16681 aagattttac tgaataatat cattttagtt tacataatga tatttctgta aattaaataa
    16741 agtagtgaaa aataagaatc agtgctctaa ctgttcaaga ggatcaagtg gttcaaatgt
    16801 ttctgtagtc tgttttgctt ccaattgggg caaaacagat ccaatttcca gatacttcac
    16861 tttattcaat gtataagata gaatagaaca gctaagtaat gtatacagaa aatgtgtgag
    16921 atccaaataa agcaaggaga caactaaaat accaaaagta atcaagaaaa gacttttgcc
    16981 aatcttaata tgaaaatatt tttcaatggc ttgataaatg atatctgttc cgcctgtgct
    17041 tccgccgaat cgaaagacga gaccgcaacc aatgccagaa agaatacctg tcatcaaact
    17101 attgatcagt agactatcta cagcaaaatg tatatgaagg ctctcccata aatgtaaaaa
    17161 gaaaactagc gcaaatgttc cgacgatcgt ccggagaaaa gcgtgttttc caaaaagaaa
    17221 caatgagata agcaataaag gtaaattaaa aagcagtgaa gtgacagaag gagcgaatcc
    17281 aaaaagatta tgcaaaagca aagcaatacc agtaacccca ccatctgcca gcttagatgg
    17341 aatattgatt cctgtcacag ctaatccgta gattcctgcg cctaaaatga ttccgcacaa
    17401 ttctgtaaat aaatttaatt ttttcatttc tagcctcttt tcttttgaaa attttcagca
    17461 acttctttat tatactgact tatactctta cttcaagagg aaaatgaaaa aaaattattt
    17521 ttggctgttt ctttttattt atcaaataag gagtggaaaa atgcgagcag cagacttatt
    17581 gacaattctt acaaaatcac ccaaaaaaac agagtatcaa ggagtttttt tggctcaaga
    17641 acaaaaactg gtgcctgtga caatggtcca gataaataaa gcaaatcaat ttatcttttt
    17701 atttgaacac ggcaaagcac cacttgctat gaaagacatc tttctttttt tgatgaagaa
    17761 ccgtgagaaa gctgtttatt atcagtcaaa agaagaactc attcctcttt atggagtgaa
    17821 agagatagaa aataaagtgg tgatataagt aaaaataaga aaacaagacg tttatgatgt
    17881 caaaacaacc attttttaca tttttggcaa aaaagtgtca tgatacagta taatattcgt
    17941 tgaacaggcc aataaaggtg ttctccccca cgagatttct actttattgg ctgtttcttt
    18001 ttattaaaat aaaagttgtg tgtgtaaaaa agatatagct gattccaagt gacaatttcg
    18061 tatagatttt tatggtattc gtagtgaaaa aacgagaacc aaaaagttga tccgactttg
    18121 ttgcttggat tctttttttg tcagcatatt tagaggtatt tttttctttt ttttgttcgt
    18181 gctgtaaggt taaggcaaga caagttagtt gggaaaaagg aaagaaatgt ttatacttaa
    18241 agaataacag aaaggaaggt cgcatgaata attttataca aacattaagt gaaagaaaag
    18301 gcgagttgct ggaagctgca tttcaacatc tgtccatttc tctcatttct ttgctgattg
    18361 cagcactgat tgctattcct ttagcgattt gggcagccaa tcataaaaaa atggcagaag
    18421 tcttattgca gatcacgggt gtgctccaaa cgattccttc acttgcctta ttaggtttac
    18481 ttatcccatt tgtagggatc ggaactgttc cagcattgat tgcacttgtt atttacgctt
    18541 tgcttccgat tttccaaaac acgtatattg gtctagctga aattgacccg tctattgaag
    18601 aagcagcggt agcatttggt atgtccagaa tgagacgctt gctgaaagta gagcttccca
    18661 tcgcattacc tgtcattatc tcaggtatcc gaactgcctt agttttaatc atcggtacgg
    18721 ctactttggc agcattgatc ggagcaggtg gattagggac atttattttg ttaggtattg
    18781 accgaaatac acctgttttg acattgattg gtgcgatcag ttctgccttg cttgcaatta
    18841 tattcagcgg actgattcgc tggttgcagc ataagaaacc tcgatattcc atcattactt
    18901 tagcagcagt ggtgtgttta tttggcggcg tttctttata tcagtctgcc ttgtttaaaa
    18961 atgaaaccat cacgattgct ggaaaattag gagcggaacc tgaaatcctg atccaaatgt
    19021 ataaagaatt gattgaagac aacacaaaaa cagaagttga attaaaaccg aattttggca
    19081 agacgagttt tttgttcaat gcactggatc aaggtcaaat cgatatctat cctgagttca
    19141 caggtactgt cctagaaagc ttggtgaagg tacctgaagc aatgaaaagt gctgatttga
    19201 caaaagaaaa aacatatgac gaagcagaag aattattgaa taagcaattc gatatgacat
    19261 tattaaaacc aatggcttac caaaatacgt atgccttggc agtcaagaga tcttttgcga
    19321 acgaacatca acttaaaaag atttccgatt tggcagctat ctctgatcag atcaaagcgg
    19381 gattcacact ggaatttatt gatcgttcag atggatataa aggaatccaa gaagcatatg
    19441 gcttgaattt ttcaagtgta caaagcatgg agccaagttt gcgttaccaa gcaatcaata
    19501 atggagatgt caatattgtg gatgcctatt ccacagatag ccagctcaag gagtacgatc
    19561 tagtgactct agaagatgat cgagggttat tcccagctta tcaaggcgca ccgctgatga
    19621 aaaaagattt tgctaaagaa catcctgaaa tcgttaaagc actgaataaa ttaagcggaa
    19681 aaataacaga ggatcaaatg attgatatga attaccaagt caatgtcgaa aagaaaaagc
    19741 cgacagaagt agcacgaatc ttcctgaaaa atgaaggatt agtaaaggag gaagatcagt
    19801 gactaaatta atcgagttca aacatgtgca aaaaaagtat gatggaaagt atgtcatcga
    19861 tgacctaaat ctggcaatca aaaaaggaga aatctttgtt ttggttggtc cttccggtag
    19921 tggaaaaaca actactttga aaatgatcaa tggattatct aaaccatcag caggagacat
    19981 ctacttcaaa ggaaaatcgt taaatgaata taatctgcag aaaatgcggt ggaatatggg
    20041 atatgtgctg cagcaaatcg ctttgttccc gaccatgaca gtcaagcaaa atattgaagt
    20101 catccctgaa atgttaggtt gggaaaagca gaaaagagca gaccgtgtag atgaacttct
    20161 tcaaaaagtt ggcttatctc ctgatattta tcgagatcgt atgcctagag agttgtctgg
    20221 aggagaacag caacggatcg ggatcatccg agctattgct gcaagcccag atgtgatttt
    20281 gatggacgag ccatttagcg cattagatcc gatttcaaga aactcattac aagaattggt
    20341 tttgtcctta cacgaagaat tgggcacgac catcgttttc gttacgcaca atatggaaga
    20401 agcaatcaag ctaggtgatc gtattgcatt tatgaaggat ggagaaatta tccaatgtga
    20461 cacaccagag cagttattga tgaatcctaa aaacgactac gttcggcatt tctttgatga
    20521 accgaaacag acgaaagagt ggcgagtaga agatttagtc gtcaatggat atttcttaaa
    20581 tgaaatacca gaaaatgctc gtcaacaagt ttgctttgat acgcctatga aagaagtata
    20641 ttcgcttctt tcggtgtatc caagcattgt gatagtagaa aagcaaagaa gtattgggtc
    20701 gctgacaagt aaagaaatct ttgctttttt aagtcgagag gaggaaggaa atgaaaacat
    20761 atgatgcaat catcatcggt tcaggtgtga gcggcttaag tgctgcttat ggattgaaag
    20821 aagcaggtaa aacagtacta gtggtcgaag aagatctatg gggcgggact tgtcctaacc
    20881 gtggatgtga tcctaaaaaa gtcttgttaa gtgcagtaga ggcacgtaat cgggtaaaac
    20941 aattgagtgg aaaaggtttt aacgagatcc caactgccaa ctgggaagaa cttcaaaaat
    21001 tcaaacgaac atttacggat ccagtcccag aaagccgaaa aaaacaatta gcagaagctg
    21061 aaatcgatca tctttcagga accgctcgtt ttttggatga ttcatctatt gaagtcaacg
    21121 aagaagtctt ccatgcggat tacttagttt tggcaaccgg gcaaagacct acgatcttac
    21181 cagtggaggg aaaggaatac ttgaaaacta gtgcagactt tttatcattg cctgtactgc
    21241 ctaaagaaat catttttatc ggtggtggtt atattgcttt tgagctagct acgattgcca
    21301 atgctgcagg gagcaaagta accattgtcc atcataatca acggccatta aaagaatttg
    21361 aggcgtcttt ggtagaggaa gccgtccatc aaatggaagc atctggcatt cagtttgctt
    21421 ttggtgttga aacccaaaag atcatttcag aaggtactcg ctatcgttta gtcggaaaag
    21481 agacggaatt agtagcagat atgatttttt gtgcgactgg gagacagccg aatacagaat
    21541 ctttagcact tgagcaagcg aatatcgtct ttgataaaca cggaattgca gtcaatgatt
    21601 atctgcaaac gagcaatcca aaaatttttg cgtgtggaga tattgtttca aggaaaaccc
    21661 caaaattgac accagtcgcc acttttgaag gaaattatgt agctaagcgg ataacggatg
    21721 caacaagcga acctatcaaa tatccgatta tacctacgat cgtctacgcc agtcctaaac
    21781 ttgctgaagt aggagttaca aaaagtcacg cctcttcgtc agatcaagtg gtagagatgg
    21841 atcttaccag ttggttcacc tatcatcgtg tcaatgaacc agttgctaag gctgaattga
    21901 cctttgacca gcaaaattat ttgattggtg ctgcagtgat tagcgagcaa gcagacgaat
    21961 tgatcgatga tttgacactc gtcatcaatc aaaaattgac taaaaaagag ttggatagct
    22021 atatcatggg gtatccgaca ttggcaagtg atctctccta tttattgaaa taatcagcat
    22081 gataactaaa gcgcttgttg ctttttcctt cttgtgctac actttaaaaa atgaatacct
    22141 gtttctgggg atgtcgtaga cgacatgaga gtaagttgtg aacttagacc cattgaacct
    22201 gtcagttaat actggtgaag ggagaaacat agcagacgct tgaagcgggt tactatgtcg
    22261 tgcccatttc aagcgttttt tgttattcat attagaagaa aggaggtaac aaaatgaaga
    22321 aaaatcttta tccagcagtc agtatggcat tcattttaat tatttggcag attgttgtca
    22381 tagtttggaa aatacctgcc tttattttac ccggacctgc tgctgtattt tctgcattag
    22441 cggcagatgc acaagtatta ctttcccatt ctgtcacgac attaaatgaa gcagtgcttg
    22501 gtttggtaat agctagcgtt ctttctttta ttactgcctt ggcaatggat tattggaagt
    22561 ttttagaaat gtctttttat ccgttactag tgatttcaca aatgttgcca atcatggtgt
    22621 tagggccatt acttacccta tggtttggtt tcggtatgct tccaaaagtg atccttgttg
    22681 tcttgataag ctattttccg atcgtagttt ctttttcgga tacattgagg aaagtatcaa
    22741 aagagcaaat catctttttg aaaacgatgg gggcagatac agggaagatt tatcgaatat
    22801 ataaaatacc agcgggttta tccggcttct tttccggttt aaaagtggct gctacttatt
    22861 gtgtcagcgg agcagtcgtt ggagaatggc taagcgctca agcaggctta gggtattaca
    22921 tgatacgcgt aaaaaacagc taccagatcg ataaagtttt tgctgcgatc atttgtgtca
    22981 ttctattgag tttattgctg aatggcgctt gttcattatt gaaaaaaggg tattatcgta
    23041 tgctttatat tttttaagag aaggggatca aatgaaaaaa ttatggcttt tattaccgct
    23101 actgttgctt ttatccgctt gtggcactgc aaaagaaaca agtagcaaac aagaaataaa
    23161 ggatttgaaa aaagtgacac ttgttttgga ttatgtaccg aatactaatc atactggcat
    23221 ctacctagca aaagaaaaag gctattataa agaggctggt ttaaatgtcc aaatcatcga
    23281 accaggagat aattcgacaa gtattggtct agtaggtgcg gacaaagcac aatttggtgt
    23341 aagttatcaa gaagatgtca cttatgctca cgcagatgga cagaatatac cagtcaaagc
    23401 aattgctaca gtgatcaaac ataatacttc tggattcgcc accctatcag acagtaacat
    23461 ccattcacca aaagattttg aaggaaaaac atatgcaggt tggcaaagtc caagtgaaga
    23521 agctgtctta aaagctgtga tggaaaaaga cggcggggac ttttcaaaac tgacaatggt
    23581 aggaagcaat ggagaagggc cagaaagctt aggaaaatcc tcagatatcc aatggtactt
    23641 tgaaggttgg gatatgatca aagcaaaaga agcgggtatt gaactaaact atatcccatt
    23701 gaaagaatta gatgaacggt tagattacta tactccggta attattacga atgatcaact
    23761 gatcaaaagt gatccagaat tggtacagtc ttttatggat gccacgaaaa aaggctatca
    23821 ggaagctatt aaggatccaa atgacagtgc taaactgttg caaaaatatg caaaagaaaa
    23881 tgatcggacg tttttagaag aatcacaagc attcttgtca aaaaattata cggatgatcc
    23941 tgagaattgg ggattgatgg aagaaaaagt ttggcgcaat tatacagctt ttatgcagga
    24001 aaacggattg atcaagcaag atgtaccttc gcaagaacta ttcactaatc agtttataaa
    24061 ataggagtga tagatatgtc aatccaaatc agccacttga atgtagtcat tgaaaacctg
    24121 aaaatattag aagacatcca tttcactatc cctaaagata cctttacatc gattgtcgcg
    24181 ccaagcggag ccggtaagtc aacattgctg aaaactttaa caggagtcca gcctatgact
    24241 tctggaacga tcaaagtaga cgatcaaaaa gtaactggtc tccatacagc atttagttat
    24301 atgccgcaag aagatatgtt acttccttgg ctgagcgtct atcaaaacgt tacgttatat
    24361 caaaaaatca atcatctaac aatcaatgaa gaacaagtaa gggattatct ggatatcttt
    24421 gggttaaacg gctatgaaca ttttttgccg gaacaattat ctggcgggat gaagcagcga
    24481 acggccttgt tacgaacaat catgaatcct tcttcttact tgcttcttga tgaaccattt
    24541 ggagcgttag atgctatgac cagagggcag atgcaagact ggatgttgaa gctgcctaaa
    24601 aaagcaaagc ggactacttt acttgtgacg catgatatcg aagaagcaat ttatttatca
    24661 gacaggattc ttgtgctttc cgcccgtccg gcacatgtga ttgctgagat tcaagtgcct
    24721 gaaaaacgac ggtcacgtga atggctactg cagcaatcag agttgaagca aacgatttat
    24781 cagttattgg caggtgaatt agatgttaag tgatgctcat tgtcatttag atgggagtca
    24841 gagtttagca ctccttcagc aggaacacac gattttgacg atcatcaatt gtgattcgcc
    24901 agaagaatgg aaggaaaaca gacagcttgc agcaagtaag actcaagcct taagttacgg
    24961 tatccatcct tggaaagcag atagctatac gtttgaacaa gttgagcctt ttttgaaaaa
    25021 agcaaggatc atcggtgaaa tagggttaga taatatttgg acgaatgtac cgatgactac
    25081 acaaaaaaaa gtatttgagc gacagcttgc ttttgcagcc ataaatgaga aacctgttgt
    25141 actgcacaca aaaggatgcg aaaaagagat cttaaattat atccaagctt accctaatca
    25201 ctatttgatc cattggtatt cttctttgga ctatcaacaa gactatattg atttaggctg
    25261 ttatttcagc attggtcttg atttgaaaaa gaatccagca gtctggcaac tagctaaagc
    25321 agtcccaatc gaccacttac ttattgaaac ggatggacta catgcagcag agtgggcttt
    25381 aggggggatt ttttcagaaa aagattatgt ctcactgctt gaagaacagt taaagacaat
    25441 cgctgagatc aaagagctat cagttgaaga agttaaaaaa aatacttatc aaaacttgga
    25501 acgtttcatt agattaggta aataaaaaag agatgtgaca caactagtgt cgcacctctt
    25561 tttggctttc tttgtataaa agtaaactgt ttgattaata aatgaatctt agtaccaacc
    25621 gtttgcttcc cagaatgctt tcgccgcttc ccaagaacca taacgtgaag taacatattg
    25681 ttctgctact ctttcttggt ttgcagcaga gtagtcacca tttaagtaag aagaatctaa
    25741 ttggtaacgt ccgatgtaac gtccgttcgt tgctgtgtaa gaaccgcttg attctttttg
    25801 tgcgatccat tcttttgcag agcttgtgct tgctggagta gcagcagttt ctgttacagc
    25861 aggagcaggt tgtgtttcag caacaggcgc tgcttgtttt tccgtttgaa ccgtttcttg
    25921 tacaacaggt tgttcagctt ggactggtgc ttcttgaacg gctgcttgag gttcagcagc
    25981 tgcttgtgca gagccttctg ttgggattgt taattgttgt cctgagtaaa tcaggttaat
    26041 atcagaaatt gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt
    26101 ttgagaaatc gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc
    26161 agtcgttccc atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt
    26221 aagtgatgtc atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg
    26281 aggaatactt taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca
    26341 aatccgcgtt ttttgtaata aatacagtaa tctatgaaat gaaaagggtt acgtttaata
    26401 aaacttgctt ttttgttttt gttcaccata aatatttatt taagaaagta ttaacctgca
    26461 tttttctcta taaaaaagat tttttaaata gataaaaaag gaggattaaa tgagtatttg
    26521 atagtattta tattaaaatt acatatgtaa tttaaaaacg cttgacattg tgtttgagat
    26581 cacttacttt tagcatgtaa aagtattgga ttaaggagct atgcaaatga aaaagaaatt
    26641 tattactggt gggattgtcg ttgcatttct atgtctaatt ggctacacag gcacgcggta
    26701 cgcaaatgaa attattttgt ggggtggaga gacagatatt gatacaatca atgagaatct
    26761 gacacagctt gatcatacat tgacagataa agagcaagcg attacagatc ttaccgctcg
    26821 actagcacaa aaagaacaga cattgcaaga ttcaaaggca gatgtccaag aataccaaac
    26881 aaaagtaaat gaattagaaa accaaaaaaa tcaatcggca gcagaaaaac aaaacttaga
    26941 aagtcaatta gtcagcaagg atgcacaact acaaagcaaa caaaatgaaa tcaatgtcaa
    27001 actagatgag atcaaccaaa aaaatgatga aatcaatcat ctgaatgcag attggacagc
    27061 aagactacaa gaagcacaag caaaactttc agaattacaa aatactgtaa atggtttgaa
    27121 tcaacaaatc gcaacactga cacaagaaaa aacaaatgta gaaatcagtt aacagataca
    27181 caaaagaaat tagacgaagc aactgctgaa aactcaagct tgaaacaata tattcaaaag
    27241 ttagaaaaag caaaagatga agtggaagat acagctgata aatctcagca aattgttgaa
    27301 gaacatttgc gtaaataatc tttcttaaca agtaaaccta aattagtaaa gaagcaacag
    27361 taatctatac tgctgcctct tttttttagt acatgtcctt catcttcgca ggaagtgcca
    27421 atatgatttt aagaaaggta atagacaaaa agtcaaaaag ataaaacaga gtttcttctt
    27481 tacaaaggga atgtatgttc gtataatggt attgaggtga aggttatgga gaaaaaatat
    27541 ggaacagtag ataagatccg tactttgcaa gttagtgcca gaccgttgat ccgtttcagt
    27601 ttaaatgggg tcaattgttt gattgcttcc catagtttga acttcctagc tgaagtagac
    27661 gaagggatga agttagtcgt tacaggttat tataataata gaaagcaatt tgttgtgaga
    27721 tcctatcatg tgttagggaa acccaaaatt gtggtagaat atgagaaaag tctataccca
    27781 agaaaaaagg tccgacaaga tgaaagaata aactagaaaa caagcggctg agacaaaaat
    27841 gtcctagccg cttgttttgg aaagatggat gcagacgatg ggatttgaac ccacacgagc
    27901 atacgctcac aagaacctca atctatatat aactacatgt atttaagtat ttgtgatgaa
    27961 tcactaaact ttccaaactc atttgaggga tattgcttaa agattgaaca gatcaattcg
    28021 aagccctatt agtattcgct caatgggggg atcagaggcc ataaaaagag actagtcatt
    28081 actagtctca ggtagtggaa ttgtaggatt ttaaacgttc ctggagagta ccggtatgta
    28141 actcgaagag gtgattatca tagtcgtaaa agtaaattga agaagcctcg cctttcacac
    28201 gagaacgtcc tggttcgaca gttaaaccta acatttggat ttttgagaca aacgaatcta
    28261 tatcttgttc gtcaatttta aaagcaatat gattgtatgt ctttggcagt ttattcgacg
    28321 aattctgcat tactgcaatc cataggtcct taactaagaa aaatttttct ggatataatg
    28381 aaaatttttt tgttgactat cgtagatttc ttttgcatca aataaggtat ttaacaatta
    28441 agtatttaaa agataacttt taagttatct ttaagtaatg cttaaagcta tgttatactc
    28501 tattaggaaa tataagaagg agtataaaaa tgaacaaaca taatagaaaa ataacgaata
    28561 acaaagaact gatcttgtta ctaataggga tttggggtat ctttttactc tttaatatgt
    28621 atatgccgac tatgagagcg gatgacgtag tttatgcaag tagattagat gaacttggct
    28681 atttgggtgc ttcgatagaa cattataaga catggagttc aagaattatt atagaactat
    28741 tcttaatgtt cttttctaaa cactttatgc tatggaaatt attaaattct acgattatgt
    28801 taggaattgt agtattactt tgcaagtat
//
LOCUS       DAFEEZ010000036        27579 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000036
VERSION     DAFEEZ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.036"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..333)
                     /locus_tag="LP245_001646"
     CDS             complement(<1..333)
                     /locus_tag="LP245_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519568.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFE"
     gene            complement(508..2643)
                     /locus_tag="LP245_001647"
     CDS             complement(508..2643)
                     /locus_tag="LP245_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1519569.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(2726..4381)
                     /locus_tag="LP245_001648"
     CDS             complement(2726..4381)
                     /locus_tag="LP245_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1519570.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(4383..4697)
                     /locus_tag="LP245_001649"
     CDS             complement(4383..4697)
                     /locus_tag="LP245_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL1519571.1"
                     /translation="MNLLFQSIKSITVPELKEKILENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            4867..5127
                     /locus_tag="LP245_001650"
     CDS             4867..5127
                     /locus_tag="LP245_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBL1519572.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            5141..5455
                     /locus_tag="LP245_001651"
     CDS             5141..5455
                     /locus_tag="LP245_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBL1519573.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(5940..6494)
                     /locus_tag="LP245_001652"
     CDS             complement(5940..6494)
                     /locus_tag="LP245_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBL1519574.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(6620..8548)
                     /locus_tag="LP245_001653"
     CDS             complement(6620..8548)
                     /locus_tag="LP245_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBL1519575.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            complement(8854..9570)
                     /locus_tag="LP245_001654"
     CDS             complement(8854..9570)
                     /locus_tag="LP245_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBL1519576.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(9571..11394)
                     /gene="glpO"
                     /locus_tag="LP245_001655"
     CDS             complement(9571..11394)
                     /gene="glpO"
                     /locus_tag="LP245_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBL1519577.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(11408..12904)
                     /gene="glpK"
                     /locus_tag="LP245_001656"
     CDS             complement(11408..12904)
                     /gene="glpK"
                     /locus_tag="LP245_001656"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBL1519578.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(13040..14500)
                     /locus_tag="LP245_001657"
     CDS             complement(13040..14500)
                     /locus_tag="LP245_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1519579.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(14490..15785)
                     /locus_tag="LP245_001658"
     CDS             complement(14490..15785)
                     /locus_tag="LP245_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1519580.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVKEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(16117..16794)
                     /locus_tag="LP245_001659"
     CDS             complement(16117..16794)
                     /locus_tag="LP245_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBL1519581.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(16824..17915)
                     /locus_tag="LP245_001660"
     CDS             complement(16824..17915)
                     /locus_tag="LP245_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBL1519582.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(18016..18450)
                     /locus_tag="LP245_001661"
     CDS             complement(18016..18450)
                     /locus_tag="LP245_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1519583.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(19034..20491)
                     /locus_tag="LP245_001662"
     CDS             complement(19034..20491)
                     /locus_tag="LP245_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1519584.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENL
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIEDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(20488..22383)
                     /locus_tag="LP245_001663"
     CDS             complement(20488..22383)
                     /locus_tag="LP245_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1519585.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(22441..24216)
                     /locus_tag="LP245_001664"
     CDS             complement(22441..24216)
                     /locus_tag="LP245_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL1519586.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYLVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESSEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(24266..25762)
                     /locus_tag="LP245_001665"
     CDS             complement(24266..25762)
                     /locus_tag="LP245_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1519587.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     EIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRIWKEEDCAPVMLDGDEQYLQANTVDYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(25956..27578)
                     /locus_tag="LP245_001666"
     CDS             complement(25956..27578)
                     /locus_tag="LP245_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBL1519588.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
BASE COUNT         7812 a         5943 c         4591 g         9233 t
ORIGIN      
        1 ttcaaaagat ttatttactt ttttgtatag atttcgattg ttccacctag tcaatacaaa
       61 tgaggtaatc aggaaactga aaaaaatcaa tacaaaaaag ccgattaaga aatacagcat
      121 tttcttttct gataaaaaag cgtacaagga aaaatccttg gctctttctg gtctcgttaa
      181 tgggaaaaag acccatataa aaggaagaac aacgatcatc catcctaaaa gagccactaa
      241 cgtttgccaa atctttaacc agtaattacc ttttgaaaaa tacttatctt tcaccaaaat
      301 tgatgcaact tcttctcttg ttactttttt catatcctca cctcacgttt ttttgttacg
      361 acgtaggagt ttaccataca tttcatttct tttcacataa agtgttccta aatttttcct
      421 aagaaaaaga acaaaacatt tctcatcagc aaatgaaaaa tattttgttc tttttatcag
      481 ttgttctttt tattttttat ctcttaatta tgttgctctt tccaatacga caatgctttt
      541 cattcctcta gatatcgccg tgtacatttg tctgcgtctt ctttgctcat ctccatcgtt
      601 ttcaaatgga tataagatta catgatcaaa ttccagtcct tttgctagac tcaaaggaat
      661 gatttggcag ttttctaatc catatgaatt ttttttaatc gattcttgta gcgtttgggt
      721 ttcctcttct gtttgggtga taactgccgc tttttctcct tttagagaaa ccaaaatctc
      781 agctagtatt ttcaacaatt cttcagagga tcgaaaagag cggtattcgg gttcttttcc
      841 ttgcggtcgg atcgatacga tgtcgatctt ctcttgatcc acagcatagg ttttgaaaag
      901 ctctgtgatt gctccgctag aacggtaact atttctaaga tcataccgat ggatcggcag
      961 atggtagtca tcgaaacaac gcataatatc agcaaaagta gtggaagaat taaagattgc
     1021 ctgattctcg tcacctacta aagtaaagtg agtttttgga aataattcga tcaatagacc
     1081 taattgtgcc agggtataat cttgtacttc atcaatcaat agatagcgaa atgctggtac
     1141 atttaccttt tcaacaagta aatgacgaat agctaatata atgactgctt catcaacagt
     1201 acgtgtgggt tgccaagcat aagctgagcc atatcgtttt tcataaattc tttcaaacaa
     1261 ctgatgctca tccacccatg ccatttcttc gatttgtctg gttatttttc gatatttttt
     1321 ttgtaaaagt ttccttgcat aagctacaat actttgttcc gaatcatcag aaatcaattt
     1381 accgaataat tccaactgcc tatcttctgt caacgagagt acctgattct gcacagcagg
     1441 actttttgct tgtttcaaaa gatgattctt ccattcgctc atcagtgcct ttttcgttgc
     1501 ttgaagccta tcgatcaatt taggatgagc aggaactttc tcatatattt tttcgatcgt
     1561 ttttttagaa aggactgttt ttccattttt agtaagtcca cggataaaat tcggatgatc
     1621 taaaaacaaa ggatctgatt gttttagatt atcgataaac tttttgctac gcaaacgttc
     1681 tgtctgctcc gatacatttt ctcccgtgat acgtttgaaa taagcctctt caccttctat
     1741 ttcctctgct gaaagctgtg aaaccagctg tatgatggtt agattcagtg gatttctttc
     1801 acctaatgat ggtaggacat tcgaaatata gtcgataaac cgatgattag gtgatagaat
     1861 cagcaagtca tcggatgtca tcgtatctcg atataaatag agcagatacg caatacgctg
     1921 catgatagca gaggttttac cacttcctgc tacgccattt accaagatat tttgactttt
     1981 cacatcccga atgattgtgt tttgttccga ttggatcgta gcagtgatag ccttcatttc
     2041 attggtctca tcttggccta agacttctaa taatacgtca tcttgaatag ctacagacgt
     2101 atcaaaaaac ttgaccaaac gatctctttc caaaagaaat tgtcgtcttt ctttaataac
     2161 cgtatcgatt ttattttgac gaaccgtata agaagatgga ccaatcatgt tattgtaaaa
     2221 aagttcggca attggtgaac gccaatcata aacaagattt tcatctgcat catctgtgaa
     2281 atttgctgta ccgatataaa aggattcttt tggctcatta tccagaaagt ctacaacgac
     2341 ttttccaaag tagggacttt tcaataaacg ttcgatcttt gctagctgat tttctgcgtt
     2401 tttctgtttg atattcatct gatcgatttc tctatttttc atttcaatca tcgaaaaagt
     2461 atccaggtta tctaagtaac tgtcaaaatt caatcgaagc tcgccagcca tttctttcaa
     2521 cgactggttt ccttctattt ttgccgtatc catcgattcc cgcagttcgt tttttttatc
     2581 aattagcttt tgatacacgt tcttcagata tgcttcttct aactgttttt gtgtgttgac
     2641 catacacatt ctcctctttt tttaaagtgg tggaaccgat tagtttacct cttttaagag
     2701 tcgaatgcaa gctttttaac gagtatcatt tgttaggata tatcagttct tcaggtcgga
     2761 cagtttgata taaagaaaat gcaccatcaa ggttttttac gtggtagcca gactgcttca
     2821 agattctttc cgctagatag ctacgtaatc cgctatgaca gctgacgata tattcttgtt
     2881 ggctgtctaa ttcatttaat cggtcccgaa gttcattcaa agggatatgt ttggcttcct
     2941 tgaatttgcc cttttccaat tcttctgctg ttcgcacatc taataaaatt tttccttttg
     3001 ctagttctgt cggcaattca tgccattgta cggtttcact aagcccttct gcaatgttca
     3061 ttgctgcata tcctagcatg tttactggat ctttggctga gccaaatggc ggtgcatacg
     3121 tcaattctaa ttccggtaaa tcgaagatcg tcaaatgccc tttgattgct gttgctaaaa
     3181 tatcgatccg tttatccaca ccttttgccc caacaccttg tgcaccataa atctcgccag
     3241 tctctggatg gaagatcaac ttcagtaaaa tatctgttgc ttctggataa tagcttgcat
     3301 gatcttttcc tgatacatga atgacttcaa aagacagttc gttttctttg gctgttcttt
     3361 cacttaaacc ggtggatgcg gcagtcattc caaacgttcg tataattgct gttccaatac
     3421 cgccttgatt tcttcgagaa attccggaaa tcgtgtccgc aacttgtcta ccttgacgat
     3481 tggctggtga agcaagagaa ataagtgcat cttttccagt gatttgctgt tttacaacga
     3541 tagcatcccc caccgcataa atatcaggaa tattcgtttg ataacgttcg tctactagga
     3601 tacccccgcg tatgcctaat tcgattccag cggtcactgc tagctggtta tcaggacgaa
     3661 caccaatgga taaaataact aaatcagcag ggatggtacg cccatcatcc agtcgcaatc
     3721 gtttcccgtg gtcttcaaat ccagcgacag catgagaagt aatcacttct actccttgat
     3781 gagacaattc tttttctata aaagctgcca tttcttcatc cagtgttgga agaatatgtg
     3841 gtgcttgttc gatcaccatg acttctaaac ctcttctttt taggttttct gccatttcca
     3901 atccgatgaa tcctgcacca acgatcacgg cacgctttgg ctgtttttct aatgcatgca
     3961 tcactttatc gatatctggt acatttctaa tagaaaaaac attgtcggct tctgttatcc
     4021 ctggaatcga tggaacaact ggttttgcac caggagataa aaccaatgca tcgtactgtt
     4081 caatgtgttt ttgaccctca tgtacgactt ctaccgtttt gttttcggga aagatggctg
     4141 tcacttcatg atttggacgc acatctaaac aaaaacgagc ggataatgat tctggcgttt
     4201 ggacaagaag attttcccgt tcactgattt ctcccgaaag ataataaggc aagccgcaat
     4261 ttgcaaaaga aacatacggt cctttttcaa aaacaacgat ttctgcatct tccattaatc
     4321 ggcgaagccg tgtagcagca gacattccac ctgctacacc tccgacaata acgattttca
     4381 tcttatttcc ctcctactgt tcgatcaaac cattgattca tgccaccacg tacattcact
     4441 acatcataac cagatttctt taattcttta gctgcttgtt tactcctcat ccctgattga
     4501 caaatcacat agacggtctt ttctttgtct ccatcatatc tgtttatact ttgtaatgga
     4561 acatttttag ctccttttat atgcccgccc cggtattctg caggtgttct aacatcaagt
     4621 aacgctggat tttccaaaat cttttccttt aattctggga ctgttatcga ttttattgat
     4681 tgaaatagca aattcatttt ctgcacctca tttacatttt tataaatacc tcatggggta
     4741 tattaaacag gagctttatt aatatgtcaa ccagaatgac tcttcatttt tttcactact
     4801 ttttatattt gcataaaata ccgataaggg gtattatcta attataaaaa tagaggagaa
     4861 tgtgttatgg agattgataa taaaaatatc ctgaaccgtt tgaaacgtac agagggacaa
     4921 attcgtggta tccaaaaaat gatcgaagac gaaaaagaat gtatggatgt catcactcaa
     4981 ttaagcgctg ttcgttctag tattgatcgc gtaatgggca tgatcgttgc agataatctg
     5041 aaaaattgct ttgagaaacc tgatagtaat ccagaagaac aagcggctaa actagaacaa
     5101 gcgatcaaga tgattattaa aaagtaaagg aatgatttca atgaaagtcg ttttccatat
     5161 tgatgaatta gaaaaatggt cagaaacagg gaaaaacgta aaaaacctga taaaagcttc
     5221 tccagaaacg acgattgtcg tatctgtaaa tggcatcgcg attaccggtt atctagactc
     5281 tgccaatgca gaattcttag atttgcaagg agtcgttttt cacgcttgcg ccaatgctat
     5341 gcgtgctaat catatttcag aaagttcttt acctgaacaa gtaatcgttg taccagcagg
     5401 tgtccttgat ttagttgaac tgcaatccca aggttatgct tatatcaagc cttagtcagt
     5461 agaggttgcg acagaagtga tcagcttcaa gaaatttcgg cttatttttc gaagaagcta
     5521 cttctggaaa accgtgaatc aaaggttgtg aaaacgctgt cctgcatcaa gtaataagaa
     5581 cagccaaaca aaaatagctt ctcatatttt tcgtttggtt gggcttatta ccgcagatgc
     5641 aagcttttga acaccgttta aggaagaggt tgtgaaatca gcggtttgac ctaagtatta
     5701 gagaaaaaaa cgggaaaata gctcctcata ttttgccgtt ttttgagcta ataccgaagg
     5761 tcagctgatt gaacaccgtt taccaagagg ttgtgagcct accatttaac tccgaatcac
     5821 aagaaataat ttcaaaaaca acttctcctg tttttggttt ggttggctta ttatcgagaa
     5881 gtagctactg ggagtctatt tatcaaaaaa aggaatgcga cataggtcac accccttttt
     5941 tattttcttt gaaacatctt tcggtactcg acagcataca agacaaaaga ttgtaaaaga
     6001 ccgtaagtga tgacggcaaa aatgactctc acccacagcg ttggtaattc tgggaaaagc
     6061 agcaaaagga tcatgccaac atagatgaca gcagtcgcta ctttgccata ccacttcgct
     6121 ccacttaatt tgatattttt agatagcccg attaatccag ctacaaacat aaagccttct
     6181 tttatcaaga atagaccaaa caacagccaa agccacggtc gataccatgc catagacaaa
     6241 atcagaaaaa gttgtgtcaa tttatctgca aacggatcaa gcaccttccc taagtctgtt
     6301 acctgattat atctccgagc aatgaccccg tctagataat cagacaaacc tgagacaaca
     6361 atgaccgctc ctgctatata aaatgactgt ctcagcacaa aataaagata aatcggcagc
     6421 aaaaaaatac ggaatatcga taaaagattc ggaatcgttt gtatttcttt acgccagtct
     6481 gtgcttaatt tcattttatc gccctacctc ctcagcactc ttttcttttt attttagctt
     6541 acacggggaa taaaaccaat gatttcactg tttttatttt tctttacagc cactgatatt
     6601 atgagctaat ttgagataat cacttgctgt tttcatcgtt tactcttctt tcttcctgtc
     6661 gtttgcgcat ttcttttact agtactttat gagctttttt tgatcctcgc tctaggtcac
     6721 gctgccgttt acgtgtttta taatcgataa acagactgtc taaatcgtaa cctgtcgggt
     6781 acagatcttc tgctgaacgc accagacgaa cacgctgacg aggcacgtgg attatttttt
     6841 tgtctaaata tacatcaatc gtatcttcac ctatatcttc ataaactaac gcttcttttt
     6901 ggtattcatt gacaaatatc cgatcacctt ttgcaaagag ctggcgttct tttttattct
     6961 ccttcctatt tgtaactgct gtcttaggaa gaaattcttt tttctgtgtc cgataggctt
     7021 tttccgccaa gtaacgctct gcttgatgga tcaatttcat cgacatatcc attttatgag
     7081 caatccacaa agcttggctt tctcctgttt ctccaacccg caactgatat ttaggacgaa
     7141 gtgcttcccg atcgaaagcc atagcagccg gcacaaaatc ttcatgatct ccggcgaatt
     7201 tcttgatttc tccataatgg gtcgtggcaa tgatcaatgc cccttgctca tacatagatt
     7261 ccatgattgc gatcgctagt gcagcccctt catttggctc tgttccactg ccaatctcat
     7321 ctaaaagtac caacgtattc ctttttatct ttttcaaaat agcagcgatg ttttgcatat
     7381 gaccagaaaa tgtactcaac gcattttcta aattttggtg gtcaccgaca tcgacgaaaa
     7441 tctcatcaaa gacagcaagc tctgtccctt cttttgccgg aacttgcata ccgaacatcg
     7501 ccatcaaagt caataaaccg actgtcttca acacgactgt tttgcctccg gcatttgctc
     7561 cggtgataat caagcctcga tagtctttac cgatttcaac atccaatggt accgcatgct
     7621 caggtaaaaa tggatgtctg ccttgcttga taatgatatg ttccgattta ttgattctag
     7681 gtgtgcttcc attgatttct cggctaaatt ttgcccgagc aaagatgata tctaacaccg
     7741 tgatcgtttc gatcaataaa tcgatcactt cttcgttttc tgcgatagca ccagtcaatg
     7801 ccgccaggac ttgatattct tcactgattt cttcagcttt taacaactga tagtgttcat
     7861 tcaatttaga aatcacagtt ggttcaataa aaaccgtcgt tcttttattt gattcatcga
     7921 taatcgttcc atctatttta tttttatagc tggctttgat aggaatcgta tagtattcgc
     7981 ctttttgaac aatcattgct tcttggatca tttctttgtt tttcggatga cgcaagaatt
     8041 tcagtaattt tgactggatt tctttttcga ttagttgtaa ttgtttgcgt actttacgca
     8101 aattacgtga cgcgtcgtca ctgactttat tattttttat tttctggtca atcaactctt
     8161 ctacatttat caaatcagga agatgtttgc tataagcaaa caacaagggt gtctggtatt
     8221 gattcttatc aaaaaacttt gtgatcatcc gactgcttct aagaaaatcc gcatattcga
     8281 tcaaatcggt tggctgcaga atcaaccctt ttttgacttg ttctgtcagt gcatcgatcc
     8341 tcggcaaccc cataaatgga acatgctgac tgctttctaa gatcaagcgt gcttctcttg
     8401 tttcttcttg acgatccaag acagtttgta ggtttgtcga gaccgtcata tcgctgattc
     8461 gttttttgct atagtttcca attgctcttg cttggatttc ctttttgatc cgatcaaatt
     8521 gtaattgact aatcatttcg ttgtccatat tctctccttt tcttgaagag atacctgtcc
     8581 caaaataaat aagggcctag agataaataa aaggatagaa cacagcttaa aaaagtcatg
     8641 tcctatcctt attagaatac aaagatattg ttttcctgac aggtaccgtt tcataagcac
     8701 accaaataaa ctttgtttat tggctattcg acttactgat tagataccag ctacactcac
     8761 aaaacatacc ccattcttct aggtcttatt tattttccac ttaactatag caagacacat
     8821 tttggttgtc aaactttagt atgttttata gatttacacc attaatgaat agacacctac
     8881 cgcgataatt gctccgatca ttggacctgc gattggtacc catgaatatg cccaatctga
     8941 agttccttta ttagctattg gcaataccgc atgtgctaat cgaggaccaa agtcccgagc
     9001 agggttgatt gcatatcctg ttggccctcc taatgaaaga ccgatggcta agatcaatcc
     9061 acctacagcg aatacgttcg ttccaggtgc aaattcgttt tgtccaaaag ctagcaaccc
     9121 aagaactaat acaaatgtac caattaattc tgtgatcaca tttgctggat aattccgtat
     9181 agcaggacct gttgcaaacg ttcctaaaat cgcgctttca tctttcgttg cattccaatg
     9241 tggcaaataa gaaagccaaa caagaatggc ccctgcaaaa gctcctaaaa cttgcgcaat
     9301 gatgaaagga acgacaagat tccaactaat tgcccctgtc atcgccatag ctagagagac
     9361 tgcaggattc aaatgagctg ggcccatgaa tccagaaata tagacagcca ttgttacagc
     9421 gagtccccaa ccaaatgcga tgacaatcca gccagaagcc tgtgctttac ttttgtttaa
     9481 attcacagcc gcacacacac catctccaag caaaactagg atcagtgtcc caataaactc
     9541 ccccatgatt tgagtcatat cactgttcat ttatttctcc ccctttagtt cccgcagatc
     9601 tgattctgca atcaatgctt ctaaacgttt agtctgttgc gccttctcct cttctgtcca
     9661 ttcaaaatat ccagcaattg catcgatcac aggttgcttg atctcatcaa gctgatctcg
     9721 ttcaaacaac agatgatttg tacgacgaat gagataatcg cctggggcca aaaccatttc
     9781 ttcttctaaa ccataacgta accgagctga ctcagcgaga ctcaaaccag gataaggtgc
     9841 catttctttt gctaattcaa agatacgtcg ggcattagtc ccgtaaaaat cagcgatata
     9901 agtagcatct tcttcctcta aaccggctgc tactccttct tttgctaatt ctgtcactgt
     9961 ttcttctaat ttagttggat cgaagtttcc acctgaaatc tgatattttt tagagtcgat
    10021 ttctttcgtc tctattccgt attcttcttt taataattgg cgtatcaatc gcaaagctcc
    10081 ttctgccatc ttacggtaat cggtgatttt cccaccagat aaagtcagca aaccatctgg
    10141 ttctctttct aaagaactac ctctggaaat cgtagaaggt gctttttcat cacggctgtt
    10201 ttccaaatgg ttcaacacgt cttctacttc agcacgagaa actttgtttt ccttatattc
    10261 acttactgta tcgacaactt tattgaagct cttgtctgaa atcgatccat tatctccacc
    10321 attgtaatca gaaccagaat taccaatcaa cagtggacga agtcctgccc agcttgcttc
    10381 gatatcattc aatgtgatat ttgcttctgg atagcgatga ttgatcacat ccaatagata
    10441 atctacatct tcttgtgtga ctttcggatc cgtaaaatct ccttggtaat ccgtatctgt
    10501 cgtaccaaag taagtcttgt tttctcttgg aatagcaaaa accatccgcc catcttgctt
    10561 tcctgtatcg aagtatgtgg gttgcggtac aggcagtttt ttcgcatcta caactaaatg
    10621 gatcccttta gttggacgca ttttaggaga gactggacgc gtaaaattca agtttcgtac
    10681 tttatctacc caaggaccac tcgtattgat cactaatttt gctttgattt cgatcacttc
    10741 atctgtcagc aggtcacgag ctttgacgcc aacgatttga tcgccatcat ataaaaagcc
    10801 aaccgctttc attttactta ctagataagc cccatcttcg gcagcctttt tgatattatc
    10861 aatcactaaa cgggcatcat tgttgcggaa atctagatag acacccgcgc cttttagccc
    10921 ttcttttttc aaaaacggtt ctctttccaa tacttcttct ggtgtcagcg tataattctc
    10981 atatttggtt cctgtcacat ttgccagttt gtcataaagg tccattgcta ctttgaccga
    11041 gaacatattg aaggttgttg ctccttcgcc ctcatagatt ggcaaaagca ttggatctgg
    11101 ttttgggatg tgtggggcaa tactttgtac gactgcacgt tcaccaactg tgtcagctac
    11161 tacttccaca tcaaatgtct tcagataacg aataccgcca tgaacaagtt tggtcgagcg
    11221 agaggaagtc ccttctgcaa aatcctgcat ttcgatcaat cctgttttga ttcctgatgc
    11281 tgctgactgg actgccacac cggcaccagt gattccgcca ccgatgatca acagatccaa
    11341 ttcttcttgc tgcatttttt gaatgctatc ttgtcttgtc ttgtttgaaa acatatggat
    11401 ttcctcctta ttcaaatgct tgggtagctt ttactgcttt tttccaaccg ttgtaaagtt
    11461 tttctcggcg ctcttcctcc atttgaactt caaatagctt gccagcttca taaaattcgc
    11521 ggatctcgtc tgtatctttc caataaccga cagctaatcc tgctaaaaat gctgccccta
    11581 gcgccgttgt ttccaagttt tctgctcgtt ggatcggtac attcaagata tctgtttgga
    11641 attgcatcag atattcattg tttgctgcac cgccatctac tttcaataca ggaatcttga
    11701 ttccagtgtc atcttgcatc gtatcgatga tatctctcac ttgataagca atcgactgta
    11761 aagtagcttt aatgatatct tcttttgtcg taccacgtgt caagccaaac atagcccctc
    11821 gtgctgcctg atcccaataa ggagcaccta gcccaacgaa tgcaggaaca acataaacct
    11881 catcttcgct tgtagagcgt ttcgctgcgt cttctgaatc gctagctttt tgcaacattt
    11941 gaagtccatc tctcagccat tgaatcgaag aaccagccac aaaaatactt ccttctaaag
    12001 catagtaaac ctttccattt atgccgtaac caattgtcgt caataaatta tttttggata
    12061 attgcggttt ttcaccggta ttcatgacaa taaatgaacc tgtaccataa gtattcttga
    12121 ccatgcctgg ttcgaatgcc atttgtccga ataatgcggc ttgctggtct cctgccatcc
    12181 ctgaaattgg tgcttcgctt ccataaaaat gataaccttg cgtataacca taaacttctg
    12241 agttagaagt gacttttggt aacatcactc gaggaatatt tagtaaatct aaaatctcct
    12301 gatcccaatc tagctgatgg atattgaaca acatcgtccg actggcattc gagtaatcag
    12361 taacatgtgc ttgtccatcg gtcagtttcc atactaacca agaatcgatc gttccaaaca
    12421 tcaattcgcc tttttcagct cgttcttgcg cgccttctac atgatcaaga atccagcgta
    12481 tcttcgttgc tgagaaatag gcatcgatca ctaaccctgt tttttcgtgg aaaaattctt
    12541 gatagccttc attttttaag ttatctgcaa ttccagctga ctgtctggat tgccaaacaa
    12601 ctgcatgata gattggacgt cctgtatctt tttcccatat tactgttgtt tcacgctggt
    12661 tcgttatgcc aatcccagca atctgatttg gtttgatccc tgattcgatg aacgctccgg
    12721 caataactga ctgtacagaa ttccagattt catttgcatc atgttccacc caactttctt
    12781 gcgggaaata ttgcgtgaac tctttttgag aactgccgat gtgtcttcct ttcttgtcaa
    12841 agataattgc tcgtgagcta gttgtacctt ggtcaatcgc catgatatac gttgattctg
    12901 tcattgtgat tccctccatt atatgcaaac gctttcttta actactctta tcatactact
    12961 gttttaaaaa aagaaactgt caaaatttta ttcttttttt ctttttttga cagtttttta
    13021 ttatgaagct attttttaat caattctttt cttttttcag cgtctctatt cttcttttca
    13081 atcgaataat gtcgtaaggt gacgcaaatt ctgacagata atattcacac tgttttttgt
    13141 ttctctggca aaatgtgatc accaaatcat attctttacc ttcttcataa cttccaatct
    13201 caataccgcc gattcccctc agttctctga tcagatattg ttgaaaagca atacgataaa
    13261 tcggcagact ttctaaatcg attccaatca ctactggttt tgcaatataa aaatcgatca
    13321 tcaaaagaac attggcatac tggatcatca ggtaactaag ctcactatct tcagctcttt
    13381 tcctcggcaa ttgctgcacc gctgtttcct gtaatttcgc cagtaactgt gttaaggaat
    13441 gcccgagcat tttctgctgc tgttccaaaa gccgatcacg ctcatagact tcgatctttc
    13501 caacaaagaa aaaccattca ttgttgatct gggaaatttg gtagcctact gccttttctt
    13561 ctttgatttt caaacgacga ggacgataat gccataacat cgtttcccga atgtaagtat
    13621 ctaaaacagc ggttggtaac tttttgctcc gtgtcaaatc atactgataa aatatttctt
    13681 cgtctactat cgaaaaagaa acaaaaaagc tgtaaaacat cattgtttcg tatacattca
    13741 gttctgctgc tgttcgacta agatgcatca cgatgattgg atcgattgct tgataaagcc
    13801 ggtccgactg atagagtaat ttcttttctt tcaaagttgc gtacgtactt ttttcattca
    13861 atagtctttt tttcgtaatc ccgagccagc aagcaatctg tgcttctgct gatgccgtaa
    13921 acgttgtttc taatacacgg tccaatccta gaatgaacgg tcttttttct ggtgtatttt
    13981 gcaaaaaaag cggtcgctga tcttccggga tatattggaa tagttcataa taaaaatatc
    14041 gtatctgtag ctcttctccg tataattgac cgtttttgat ttgtaatcca aattcctcta
    14101 agagctggtt caattctttg atctttcgaa aaacagaaga ctcactgata ttaaacgctg
    14161 tcgctaatcg aacgatggat acttgctgat gttctaataa atagacgagc atcttaaact
    14221 tcaagctttc ctgcaataaa aacaatagaa ttttttccaa acttacatct tcgtccaaca
    14281 caagcagcgc ctgatactca tttcgctgta cttctacttt tttttccatc attcggccaa
    14341 tcaattcaat atcttccaaa tattgatcaa acgaggcttt tgacagttgg acatgctctc
    14401 tcaaaccatt gatagaggct gttccccctt gcagaacaag gtttcgcaaa atcaggatct
    14461 gtaactgctc ttttctttct aataatgctt caatcttcat aggcagtatt cgccaccttt
    14521 gaccacacca tatctggcac acggtattct ggctggaaaa atagctcatg ttcttctaac
    14581 tgttcaaacg tccatccttc ttttactgca attgtcagtt ggtcaagaag gtggaacatc
    14641 tcttttttgc tttggagctg tgctccaaga atcttttttt cagaatcaaa tagaaatttg
    14701 agtttaactt tgctttgatt tattgctgta agcttgtagt ctacgtatcc tgtttcaatt
    14761 ttttggggat aaaaaatgct ctcttcttct gtcaaaccta cgcttcctaa gaaatagcca
    14821 aaccactgat tgccgactgg acgataggtt ccctgatcct ttgtctgtga gccactaatt
    14881 gtcttgctga catttcgtgc tgtacggaca gcgttattta ctagagaaac atacattttt
    14941 tcatttgttg gacgaaaagt tacttggatc gcatcgccaa tcgcataaac gtctttttga
    15001 gacgtttgca agtagtcatc tacccagatc gttccatcat cattcaatgt taattgttct
    15061 tcccacatct gattgtcggg gcgagaatga ttagccagca aaacaagatc atagttctcc
    15121 tttctttttt ccgtctctac aatagcggtt tcattttcgg tcaaagacac aacttgttct
    15181 tctaaaaaaa gtgaaagccc ttgatttttc atttccttta ctaacggttc tgtcatttca
    15241 ggatctagat aacgaaaaag aattgacttt cggctttcgt aaagatggat ttgttttttt
    15301 cttgatgcca acccttcagc tatttcgatt cctgcttgtc ctgcaccaat aattgcaatt
    15361 ttctttgcat tcatgatctt ttgctgaaga gccgttacgt tttgtatctt tttaactggg
    15421 tgaataagcg ttgattctgc agaaatattt cgaaactttt gatttgaacc agtcgctaga
    15481 atcaaacgat caaaatccaa tttttttcct cctgctaaaa cgactttttt ttctttcaat
    15541 cctattactg tcttttctgt gtaaacatgg attcgatagc ggtcagtcag ttcttctttc
    15601 gtgatccaag aaagttgttt ttcactggta acctttcctt ttaatatcaa attgaacccg
    15661 ctgggaatcc atcctaactt cgattgcttt tcaatcaaat atatttcact tgttggcatc
    15721 aattggcgaa gataaatagc cgcatgaatc cctgcaaacg acccgccgac aattacaatg
    15781 ttcatctgca ttcctctttc ttataaggtg ttctactgct aacttctcaa tcagaaaaca
    15841 cagtattcat aactcgcttt caaccttatg atacatagcg atgcagcaga atcaaccctc
    15901 tccatcatac cgtgttctag gtctgcttct caataatgta ctagtggacc taattgaaga
    15961 gtatcatttc tgaagagatg tttcaaaaaa tgtactctta taaaagaaaa aaactcgcct
    16021 tttacgtacc tctgtccaaa taggaaacag aaaagaacga aaagacgagt tttagcgtgt
    16081 gtaatgtaat agttagaata gacacatcat ttatttttaa ttctttaatg cttcaacaac
    16141 tgcttcgcct aattgatgag cagattgagg attttgccct gtaagaagcc gcccatcaat
    16201 ttgaaccact tctgaaaaag ctgctccaga ctgatagttt gctccttttt ctttcaaagc
    16261 atcttctgct aagaatggta cttcattcgt tgtaccattt gcttcctctt cttcattact
    16321 gaacccagtc actgtacgtc cagctaaaat agattttcca gactcatctg taactggcaa
    16381 caatcctaca acaccgtgac aaacagctga gaccagccct tcatttcgat agatttgtga
    16441 agcgactttc ccaagatcta ttgcttctgg aaaatcccac attgttccgt ggccaccagc
    16501 ataataaacc gctgcataat catttgcatc cacatcatca ggacgtaagg tatttcccaa
    16561 ggcccgattt ctgaaatctt catcttcata ataggcccaa tcgatttcat ccatattcaa
    16621 aacactttgc ggttctaaag gtacatatcc gcctttagga ctgacaaaat ctgcatcgat
    16681 cccatttttt actaatacat cataaaaatg agtcagttca cttaaccaca aacctgtagg
    16741 acgctcgatc ttttcgtact tttctacatt tgttaatacg atcaatactt tcattttccc
    16801 atcctctttc tataaaaatt gcgttattga taacgtgctt tcaagaaatt atataatggg
    16861 cttggcaaat aaagctcttt atatgcttct tcaaaaggtt tcgttacaaa ttcatcctca
    16921 cggttttcca ataatttctc tgcccagtca ggatcgacga tcatttgctg tccaattgct
    16981 gcaagttctg catatttcaa tacctgctct acatcttcgc gattgcggat cccaccgaca
    17041 ccaactaaag ggatctttcc ttgaatcgtg ttatggacca cttcaagaat cgatttatcg
    17101 ttgtatttat cagaacgagc tattcgatca tacatattta atgaaacatg cagataatct
    17161 agttttgact cacgtaatcg ttcaagaagc cagatcgtgt cttcaaaacg gatacctggt
    17221 gtttcatatt cttctggtga gaaacgatac cctacgatga atggtttttt agcatattgt
    17281 tcaaccgctg agaaaaccgt tgttaataat tcttcaataa aacgataacg attttccaag
    17341 ctaccgcccc attgatcctc tcgtctattc gaatgcggag agaaaaattg ttggatcaaa
    17401 tacgtatttg ctccatgcaa ctcgattcca tcaaatcctg attcaatcgc tctacgtgtg
    17461 gctttgccaa atgcttggat tgtttcaacg atttcttctt cactcattgc tcgtggtgtt
    17521 tccgcatcag gacgttttgc tgcaactgca cttgcagata caggctgttc tccagataaa
    17581 gttgctcgac ttgtcattcg tccaccgtgg aaaatctgaa taatcgcttt tgcgccttct
    17641 ccttggattg ctttcgctag ctcacttaat cgaggaatca tttcatcatg agcgatgctg
    17701 agttcacctg gccagccttt tccgatatct tggacatttg cagcaccagt aataacagca
    17761 ccaagacctt tagaacgttg tttataataa gtgatctcat cttcggtgat cactccattg
    17821 aaaaagctga gttgtgtcgt cataggcgac agcatcaatc ggttcttcaa ttgaactcct
    17881 gaaggtaaag taattgattg atcaaattgt gacattgtca ttcctcccat aattcgctct
    17941 gattaaccta tcgagaatca tctatcatta aaccactcga ttagttgtac atgcaactaa
    18001 tttgcttaaa aaattttatt ttttttgtaa cttatctgtt gcatcattca ttgtctgggc
    18061 taattcttta cttgcttcat ttcccaaaac tgctttgtat gactgatgaa gttcttccca
    18121 gctaccatcg acttccttag caaattggcg tccttgttct gtaagataaa ctaatgacaa
    18181 gcgaccttcg ctaactgttt tgacgtatcc tttatattct aatttttcaa caaaacgagc
    18241 aatcgttgat ggggcggaat agagcatttg tgcaatatct ttttgtggta ttccatcttt
    18301 ttcttttaat atcaataaaa taaaaccata agttggtgcc agacctgtcc ttctaaacgc
    18361 ttcatcagct aatttattca acatgcgatc tagctttttc acgctaaaga aaagacattc
    18421 atctaacgct ttttcaattg gcttttccat ttcatcccct ccattggcgt acatatcata
    18481 gtatgatttt tattttttgt caaaaaacac ggaataatgt ccgcctcctc tgtctagatt
    18541 tgaaaaaaag aagtagccat cttcaaagaa tttcggcttg ttttcgacaa aactccttct
    18601 ggaacaccgt gaatcagagg ttgtgaaaaa gtcgtttagt tttgagtatg aagaaaaatt
    18661 ttgtgaaaat ggctttccac atttttgcat aaatttggct taataccgaa aaactggctt
    18721 ttgaacaccg tttatatcag aggttgtgaa aaagccgtcc tgcatcaagt aataagaaca
    18781 gccaaacaaa aatagttcct catattttgt cgttttttga gctaatgccg atggtcagct
    18841 gattgtacac cgtttattga gaggtcgtga gcctgccgtt gaactccgag tcacaaggag
    18901 caatttcaaa aaacagcttc tcatgtttta tgactatggt gacttgtgat cgaggagttg
    18961 gcaggagaat actgtttatt cgtaaagaag gggctgtgac aagacttttg tcacagtccc
    19021 ttatttcctt ttattatagg atttcgccat ttgattggat gacttgtctg taccaatcaa
    19081 atgatttttt ctttaaccgt ttctttgtgc cattcccttc gtcatcttga tcaacataga
    19141 tatatccata acgttttgac atttgtgaag tagaagcgct gacgatatca atgcagcccc
    19201 acgacgtata accaaataaa tctactccat cttcgatagc ttccttcatc tgctcaatat
    19261 gctgcttcaa atagtcaatg cggtaatcgt cttgaacggt tccatcttct tctactttgt
    19321 ctatagctcc gagtccgttt tcagctatga acagtggttt ttgataccta tcatataatt
    19381 gattcaaagc aattctcaaa cccttaggat caatctgcca gccccattca cttgatggaa
    19441 gatacggatt tttaattcct ccagttatta agtttccttg gaccccttcc aaattttctg
    19501 gatgagcact gactgcacta gacatgtagt agctaaaaga aacaaaatca acagggtagg
    19561 ctgctaagat ttcttcatca cctacttcta tttttaagtt gacacctttt tcttcaaaca
    19621 ttcgttgcgt atacgctgga taatatcctc ttgcttgaac atcactaaag aacaaagaag
    19681 ttctttgctg ctcaattgtt ttttgaatat catccggatc acaagaatac ggaacaagaa
    19741 gctgatagct gatcatacaa ccgacttgtg aacctttgat aatttcatga caagcttttg
    19801 tagctaaagc acttgctata aactgatggt gtgcaccttg gtatttcgct tgttccaaat
    19861 ggggatggtt ttcttcaatt actcctacgc taacaaaagg gtgatgtttt acacagttga
    19921 tctcattgaa agtcatccaa tattttactt tatttttata gcgtttgaat actgtttcag
    19981 cgaaacgaac gtaaaactga ataagctttc gattaggcca tccaccatat tctgtaacca
    20041 aatataacgg catttcataa tgggaaagag aaacgactgg ctcaatccca tattttagac
    20101 attcgtcaaa cacttgatca taaaaaaata atcccgcttc attgggtgtt tcttcatcac
    20161 catgaggaaa aattcttgtc catgcgatag acatccgata gcatttaaaa cccatttcag
    20221 caaataaacg gatgtcttct ttaaagtgat gatagaaatc atttccgtgt cttttaggat
    20281 aataatactt gctgttggga tcctgcgccg cttttacttg ctgatgcgtc atcatatgcc
    20341 attgatctgt ccatttttct ttaggtaaat cgctgtcgaa tgtatacaca tcagacacag
    20401 ataatccttt ttcatctaca tcccatgcac cttcacattg attggccgct gtcgctccgc
    20461 cccataaaaa tccttctgga aattttttca tatcgatccc cctaaacttg ctagttttct
    20521 tgtttgatta tttttcttat gactagtaat gatatttttg aatctactac tatttgtaac
    20581 aataaccatt gtggtcggat catatccctc tttgattaat tcttgcaaat ctacttccat
    20641 caataaatcg cctttacgta ctttttttcc atcagatact gcactttgaa agtatttgcc
    20701 atttaaattc actgtatcaa taccgatatg gatcagtatc tctgctcctt cttcactgac
    20761 taccccaatt gcatgtttcg ttggaaaaac tgttgaaact tccccgttta caggactgta
    20821 gatttttccg tccgttggaa tgatcgcaaa cccttctcct aaagatccac tagcaaatgt
    20881 tggatcgttt acttcagata aatcaattat ttcacctgct gcaggagtac ttaacactat
    20941 atcctttgag gattcttctt cgatttcatc cttgtagccg aaaagaaaag ttagcataca
    21001 ggaactgatc atcgctaaga aataactagc aactagccaa acaaatcctt caccaatata
    21061 aatcgggaaa gacaaaatac ttcttgtagc aactgccaaa gcaccggctc ctgcggcacc
    21121 agctactcca ccaaatatag ctccacatat acaagcaatg taaaatggtc gtttatattt
    21181 aagagtcaca ccataaacag caggttcagt gattccaaat aatgctgtga taaatgcaga
    21241 taaagataaa ctttttactt tcttattttt cgttttcaaa aataccccaa gtactgctcc
    21301 tgcttgcgca gctacggcag tcatacatgc tggacctagc gtatcacgac cgtagaaaga
    21361 aagattgttg gtcattactg gtacaagtcc ccaatgtaac ccaaaaatca ctaacacttg
    21421 ccaaaatccg ccgataacag caccagataa aacagggcta aagttataaa cagctaaata
    21481 tccagctgca atcagctgac ttgcataatc tgcaattgga cctacaacta ataaagtaat
    21541 tgggaccatc acgatgatac aaatgaatgg tgtcaataaa tttcgaatac tttcgtgcaa
    21601 gcttttgcga atcttaggct caatataaga aagaacccat acagctaaaa ttgctggaat
    21661 aaccgtactt gtatatcttg ctagaatcac gggcatccct agaaatcgca aggttatgct
    21721 atcactatat gcactgacaa tcgtaggata aacgagagct gctgcaataa ccatagcgat
    21781 gaaacgatct gtattgaact tttttgcagc agtatatgcc aaaaatatag gcaagaaata
    21841 gaaaaatgca tcagctgctg cattcaaaat gatataagtt cctgattcag tagttaataa
    21901 attcaaactc gtacataagg cgagtactcc tttgatcaaa ccacttcctg ccaagacgcc
    21961 taaagtcggg gcaaaaacag cggcgatcat gtctataaaa gagtttaaaa tgcctttttt
    22021 ctcagttcct ctctttccac tagatgcatc atcttctagt ttcatttgtt tggataatac
    22081 gtcatacact tcatttactg catttcctac tacgacttga aacattcctc cagcttcgac
    22141 tacagtgatc acaccttcta gttgctctac cttctcctta tctgccttct tattatcttt
    22201 tagggtaaag cgtaaccttg ttgcacaatg gtaaacattg ctgacatttt cttcgcctcc
    22261 gacaaatcgg acaatatctt tcgctaattg tgaatagtcc atttttactt cccccttgtt
    22321 aattaatgcc gtagcaatcc ttcttacaag ataagtatag ttcttagaaa acggtttctc
    22381 cattcaatta gtaccccttc taatagcgaa cgaaactgta caatagtgtg tatggtttac
    22441 ttagccgagc aaatcactca ctgcttgaaa gaaaacaagt atatcgtttc tcttatagtc
    22501 aaaggagaca aaaaaaacac gcttgatctt cctttgctga tgtataagtg gtatctcaag
    22561 ctgatactct gtgatttttg tttctacttg gcttttgata agacagcaca acaaagtctc
    22621 ggcatttaac ggaagcataa ctaggtcaga actaggagag attagttgct gaatggaatc
    22681 tatcttttta tggattttta tttgattttc ttctttgtag taatgatcaa gcagttttgt
    22741 tttctttttt tcttcaacta tggtcagctt ttcacgcaaa atctgataaa tctccgaaga
    22801 ttcaaactca tctagaacac taggtagata aatcaaatca tcccactcaa aaataagctc
    22861 ttgctcagta gtcaaaattg catcatattc cgttattttg tttgattgat ttttgaaaag
    22921 atacactggt tctatccggc attctttgat ccacatgttc atactttgtt gaatctgttt
    22981 ttttagtgta ttcaaaatac taattggctg gttactaaca atcagtatct ccccttgttt
    23041 tcgaaaagga ttcaacgctt cggcaagata caaaaccaaa taagcgcttt cagctaaatt
    23101 gggacgtaat tgaaaatgta ttgggaagaa acgccgaatt aaataaattt ctaaaggata
    23161 acgggagatg atcttttgta caaaatgatt catggtatta tgtccggcat ccatcctcgt
    23221 tttcatttgt ttgatatggg ttagcaaaaa ttctgtttca tggaacaata acgaaacagg
    23281 aagatctaaa aaacgaataa tcgtttgctc aaatgctctt agattcttct ctatttcttt
    23341 gtttttttca tcattaatca tcaaataatt taactctaat agtcgatttt caattgcttg
    23401 tttttcttga ttggaaaaag aatagggtag ttctgatgat aacttttttg tgagggtctc
    23461 taccatcgga ataaataatg tatacctgtt tgttttttct aaaagttctt ctcttcgaag
    23521 aatggtcaaa acgagatacc gagaaaatcg tatgaagtcc tctcctgaaa caatataatt
    23581 atatgatata agaacctctt ttaatgtctt ttggacagtc ggcatgatat tggaaaaaat
    23641 tgtactgatt tgttgaggca accttgcgtg ttggatcacc gtttctgttc caacaagaga
    23701 taagaaaatt ctttttgaat tttcttcagc aatgattttt agtccttttg tcgacgaaac
    23761 ttccagttct aatttaggat tgcgctcgat ccaacgcaaa atcgttttta tttgtaatga
    23821 tacggctgtt tttgaaagaa agaaaatgtc tgctatcttt tgcatactga catacccttt
    23881 ttgaaacaat aagtacgtca caatagttga agctcggaaa tccatgctgg aatagatttt
    23941 atgtttcgtc acctcttgta tgatttgctg tttagtttca gattcaattg attctaaaaa
    24001 ataacctgaa cgtttatttg actggataat gattttcttc tcgtagatag caagcatatt
    24061 tttgatttca gtttggatcg ttttcttgtt ggtacctaaa gcttcagcta attcttcgct
    24121 tgttatccaa tgattcttat ttcttaatac tacaagaatt tggagttgtc gtttatttaa
    24181 gtccatttgc ttacacctcc tctttgttat aaacatacag gaaaaacctc tcaaatgaca
    24241 atagtcactt gcagaggttt aaaaatcatt tgaagaaaga tctatattca aggtttttac
    24301 cattagactg gataatttgt ttataatatt caaaactatc ttttttcaat ctcctaaagc
    24361 ttccgctccc atcattttgt ctatccacat aaataaagcc atatcgcttc ctcatttccc
    24421 ctgttcctgc cgatacgata tcgattggtc cccaccataa gtaaccaatg atttggcaac
    24481 catcttttat tgcctcagca atttcctgaa gatgtatttt tagatactca caacgttttg
    24541 gatcgtggat tcgattcaat tcatctggtg cttcatctag tccaatgcca ttttcaacta
    24601 tgaataatgg taattcataa cggtctgtca attcattcat gacataacga aaccctagag
    24661 gatcaattgg ccaactccaa ggttcgggag atttttcctt caaaaaggga ttatcgaaac
    24721 catttgctcc gccagtatct acgcgcattt ctgcttcttt tttatagaca gcgctacgat
    24781 aataactaaa tgcaatataa tctaccgtgt tagcttgcaa gtactgttcg tctccatcta
    24841 acattactgg tgcacagtct tcttccttcc atatcctgta aatataagct ggataatgcc
    24901 ctcggcacat gacatcggag aaaaaccatg aattgcgttt aaattgcagt gaaccaaata
    24961 cattctctgg atcacagtca tatgcataag tcgctaatgc agaaaagcta cacataatac
    25021 ccatcttagc atttggatcg attttcttta ataattgagt agcacgggcg ttcgctagaa
    25081 acatatgatg acaggcttga taaatctctt tttttgttag tgtagcaatg ggttcaagtt
    25141 tatctctagc agggaatgta accaatccag cagctgcata aggcatacga aaagcattat
    25201 tgatctcatt aaaggtcatc caatatttca ctttcccttg gtagcgttca aagacggtct
    25261 gcgcataaaa ttcaaaaaag tcgattaatt ttcgattttg ccacccccca tactctccta
    25321 ccaatgctaa gggggtttca taatgactaa gagtaattac tggctcgata tcatatcgat
    25381 ttaatgtatt gattagtctg tcataaaata cgagaccagc ctcatttggc ttctgttcgt
    25441 ctcctcttgg aaatattcgt gcccatgaga tgcttgttcg aaaagctttt aaacctaact
    25501 ccttcagtaa acgaatatcc tcttcaaatc gatgataaaa atcaatcgct tcatgagaaa
    25561 gataatggag tgattcgtct aaagcaatct cccaaatctt tttttcttca ttccactgaa
    25621 tactaggatg ctggttcatg atcccgataa gcgtatctgt cacattaggt aatttgccgt
    25681 cttccaacca tgcaccttca cattgattag cagctactgc tccgccccat aaaaaatttt
    25741 ctggaaatat ttcctgatcc ataactatct ctcctcgcta tcaacaattt cttacttgaa
    25801 gtatagctcg attcatcaaa acaagatatt ctaactattt cggcagaaga gaagaaaaaa
    25861 attgaatgct actcttcatt tttaatattt atatataaca aatacataag acgatccccg
    25921 aaagaaaaca ctcgttaacc atctaagcaa acgatttatt ttacttccaa cacaaatgct
    25981 tcataaggtc gtaaatcaac tttgccgtct ggtaactgtt tcagaggata atttgacaca
    26041 ataaccctta aagcttcacg tggaacagtg aacgtctgct tttcactgga catattacaa
    26101 ataacgagcc attgctggtc ttcatatatg cgagaatagg caaagacatg ctcaggcgtc
    26161 ttttccacta attcatagtc tccccagacg atgatgtcat gttttctacg caaatcgatc
    26221 aatttcttgt acatataaaa aacagaatct tgatctgcta acgcttcttc tgcattgatt
    26281 tctttataat ttggattgac tcgaagccat ggaattccag tagtaaaccc agcatgttca
    26341 cgggcgttcc attgcatagg cgtcctagca ttgtctcttc ctttcgcatt gattgattcc
    26401 aagatttcct cttttgtaaa tccagaagaa atcctttcgt tatacatatt gattgtctca
    26461 atatcttttg cttccgcgat atcatcgatt gggcaattcg tcatgcctaa ctcttctcct
    26521 tgatagatat aaggggtgcc tttcatcata tggagcaaga tagcaaacat cttggcactt
    26581 tcttttcgat acacatcgtc atttccccaa cgagaaacaa ttcgcggaag atcgtgatta
    26641 ttccaaaata aactattcca tccttcatca cctaaagatg tttgccattt ggataatact
    26701 tttttcagtt cagagatact caagggtttc aaatcccatt tgtctttgcc ttcttgctga
    26761 tctaatccta tgtgttcgaa ttggaagacc atggataatt catttctttt aggattggaa
    26821 taaagtttag cgatttcggt agttgctccc catgtttcgc caacagtcat cagatttttg
    26881 tcaccaaaag ttgcttgatt catttcctga agatactcat gcagtttagg tccattactt
    26941 gtgatttctt tatccggttc tttgccaatc atatcgatca cgtccatacg aaagccacca
    27001 atacctttat cgatccagaa attcatcatt tgataaatct cttggcgaac ctgtttattt
    27061 ttccaattca aatcaggttg acgcttgcta tacaagtgca gaaaatattg ccccgttttt
    27121 tcatccaact gccaagcaga accactgaat attgagcgca atctattagg ctcttttcca
    27181 ttgaccggat cacgccaaat ataatagtcc cgataaggat tttctttatt tttacgggcc
    27241 tcaatgaacc acggatgttc atcagaagta tgattcacca ccagatccat gatgatacgg
    27301 atatttcttt tctttgcttc ttcaatcagt tcttccattt cttccatcgt accgaattct
    27361 gccatgattg cttgataatt actgatatca tacccattgt catcattcgg agactcgtat
    27421 actggagaaa gccaaattgc atcaatacct aaatacgcca gataatccaa cctggaaata
    27481 atcccccgca aatctccaat accatcttga tttgaatctt gaaaacttct tggatagatt
    27541 tgataaacaa ctgaatggtg ccaccatttt tgttccatg
//
LOCUS       DAFEEZ010000037        27251 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000037
VERSION     DAFEEZ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27251
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.037"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(161..445)
                     /locus_tag="LP245_001667"
     CDS             complement(161..445)
                     /locus_tag="LP245_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519589.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(463..1353)
                     /locus_tag="LP245_001668"
     CDS             complement(463..1353)
                     /locus_tag="LP245_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBL1519590.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1373..1591)
                     /locus_tag="LP245_001669"
     CDS             complement(1373..1591)
                     /locus_tag="LP245_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBL1519591.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1561..3261)
                     /locus_tag="LP245_001670"
     CDS             complement(1561..3261)
                     /locus_tag="LP245_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBL1519592.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3528..4301
                     /locus_tag="LP245_001671"
     CDS             3528..4301
                     /locus_tag="LP245_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519593.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="LP245_001672"
     CDS             complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="LP245_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBL1519594.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5017..5119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5125..6096)
                     /locus_tag="LP245_001673"
     CDS             complement(5125..6096)
                     /locus_tag="LP245_001673"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBL1519595.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="LP245_001674"
     CDS             complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="LP245_001674"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBL1519596.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8066..8884)
                     /gene="purR"
                     /locus_tag="LP245_001675"
     CDS             complement(8066..8884)
                     /gene="purR"
                     /locus_tag="LP245_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBL1519597.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9051..9875)
                     /locus_tag="LP245_001676"
     CDS             complement(9051..9875)
                     /locus_tag="LP245_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL1519598.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9848..10528)
                     /locus_tag="LP245_001677"
     CDS             complement(9848..10528)
                     /locus_tag="LP245_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL1519599.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10551..11489)
                     /locus_tag="LP245_001678"
     CDS             complement(10551..11489)
                     /locus_tag="LP245_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBL1519600.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11734..12597)
                     /locus_tag="LP245_001679"
     CDS             complement(11734..12597)
                     /locus_tag="LP245_001679"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBL1519601.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="LP245_001680"
     CDS             complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="LP245_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBL1519602.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15453..16259
                     /gene="proC"
                     /locus_tag="LP245_001681"
     CDS             15453..16259
                     /gene="proC"
                     /locus_tag="LP245_001681"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBL1519603.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16338..17894)
                     /gene="rny"
                     /locus_tag="LP245_001682"
     CDS             complement(16338..17894)
                     /gene="rny"
                     /locus_tag="LP245_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBL1519604.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18305..19354)
                     /gene="recA"
                     /locus_tag="LP245_001683"
     CDS             complement(18305..19354)
                     /gene="recA"
                     /locus_tag="LP245_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBL1519605.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19463..20704)
                     /locus_tag="LP245_001684"
     CDS             complement(19463..20704)
                     /locus_tag="LP245_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBL1519606.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="LP245_001685"
     CDS             complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="LP245_001685"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBL1519607.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21731..22654)
                     /locus_tag="LP245_001686"
     CDS             complement(21731..22654)
                     /locus_tag="LP245_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1519608.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(23393..24679)
                     /locus_tag="LP245_001687"
     CDS             complement(23393..24679)
                     /locus_tag="LP245_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBL1519609.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24672..25940)
                     /locus_tag="LP245_001688"
     CDS             complement(24672..25940)
                     /locus_tag="LP245_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBL1519610.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26192..26653
                     /gene="mscL"
                     /locus_tag="LP245_001689"
     CDS             26192..26653
                     /gene="mscL"
                     /locus_tag="LP245_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBL1519611.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26712..27158)
                     /locus_tag="LP245_001690"
     CDS             complement(26712..27158)
                     /locus_tag="LP245_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1519612.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT         7743 a         5877 c         4727 g         8904 t
ORIGIN      
        1 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
       61 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
      121 attctgatta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
      181 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
      241 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
      301 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
      361 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
      421 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
      481 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
      541 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
      601 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
      661 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
      721 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
      781 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
      841 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
      901 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
      961 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagcg cgaagcgttc
     1021 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
     1081 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
     1141 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
     1201 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
     1261 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
     1321 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
     1381 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
     1441 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
     1501 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
     1561 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
     1621 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
     1681 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
     1741 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
     1801 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
     1861 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
     1921 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
     1981 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
     2041 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
     2101 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
     2161 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
     2221 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
     2281 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
     2341 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
     2401 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
     2461 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
     2521 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
     2581 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
     2641 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc tttttccata aattcacagc
     2701 ttttttcata tctccttgta aaatcaatgc gccgttcaac gcacctaccg aggtacctgt
     2761 gataatctca aagttgatat catgttcctt cagcgcctgc cacacaccaa tctgataagc
     2821 accgtgcgct cctcctccac ctaaaacaag tgctgtatga tagaccagct ttttatttaa
     2881 ttgtgtggtt ccttgatagc cgtttttatg aaaaatacgc aaccattctt ctgatagagg
     2941 agattgaaat aaaaaacaac agttttcttt aataaaaaaa cgagcgcaag cttccatata
     3001 ccgaaaaaat tttttccatt caaaagtttc accttcaatc aacagattat taaaaataac
     3061 atctcctcta cttttagcaa tagtaaaata gacggtatat tttttcgata ctgctttaaa
     3121 agcacattgc ttttttgcag aacgccaaaa agcgtctcta ctttcttgat gactttgaaa
     3181 aaatggaagg ggttgttttg cttgctggat aggcgaatac agcgacattt tctgtgaaaa
     3241 gtaaactttt tttatctcca tcgcgctctc ctttttcttc aagtatacca gtacgtcata
     3301 aaaaggtcat gagtctcgta ttcgactttg tagattccat aagaaaacaa ttcataaaac
     3361 ctcctttaaa taaaaaaata caaaaatcac aaaaattaat tgaaaatgag agtgttttca
     3421 atgaaaacgt gattttgtaa tggaatttta aaataaaaga aacaagcttt tttaatgcaa
     3481 atgttgtaaa ataaaagaga ttaagaggaa ataagaggag gaacatgatg actgagtcag
     3541 tttatgtaca tattgatacc acaagtaatg ctgttttaac aaaagggctg actgctactg
     3601 actttgcaaa cagtatcgtg cattttcctc aaaacttgct cttgcttgat ccatctgctt
     3661 ctgctggaga atatgaatcc catacagggc tgaaagtaat ccgtggtaca gaaaatattc
     3721 agcgtttctt ttcctcttct cgtaacaggc gtggattcga tgaattgaag tggatcgact
     3781 ttactgattt aacgatgctg aaagaattga cacctttaga aatttcagaa ttattatatt
     3841 ttggtcatat gaaaacacat cttcattcgc cgttttttta taaactacag aataattttg
     3901 tatacttcga tcttaatgat cagctgaatc ggatttatta tcgctattta gatgaatttt
     3961 ataggatttt tgctagtaaa ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat
     4021 cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc
     4081 gtaatttgat gcaggaaggg atcatttttt cttttgatca agttggtttg atcgatggta
     4141 aatatcgtat cccaatctat gtgattgaag attatatttg gaaattaaaa ggcacccggt
     4201 atcgagaaga ggaaatcatc gctactttaa tctactctgt caccgatcga cactggcaat
     4261 tggtagaaga tgccgatctt tcttatctgc cattgaagta gatctatttc ttatcaaaaa
     4321 ataaaaagga aacaagaaac taggacatga ttctgtctca agtttcttgc ttctttttta
     4381 tttacagctc ctgtcgttta tctggcacaa aaatcgaagg agtcgtttgt tggatcccta
     4441 ataaaacgat gatcgttaca atagctgtac tcaacccgct ggcaccattc attacgaaag
     4501 aaaagagcca aggattcatc ccccatagtg catacgctcc ccagaaaacc actcctgcaa
     4561 taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc accaaacacg atgctttttc
     4621 taatttgttt cgtattatcg tctacatagc ctttttggac atttgaagcc atgagccctg
     4681 ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa cacttgaacg acacttaaat
     4741 aataaacttg tcccaacgga aaatgtagga tgccccaaat gaaacctgcc agcatccctg
     4801 cctttgtccc tcttcttaac gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa
     4861 aactgctgcc gatctggatc ggaatcaacg acaacaccat cgctaacgct gcaacaatcg
     4921 ttccttctac ccaaactcta ttttttccca taaaaaaact tcctcctttg aataaaaaag
     4981 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
     5041 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
     5101 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
     5161 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
     5221 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
     5281 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
     5341 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
     5401 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
     5461 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
     5521 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
     5581 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
     5641 catcaaatga tcgactggaa tatcaaagaa accttggatt tgaactgcat gaaggtccaa
     5701 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
     5761 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
     5821 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
     5881 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
     5941 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
     6001 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
     6061 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
     6121 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
     6181 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
     6241 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
     6301 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
     6361 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
     6421 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
     6481 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
     6541 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
     6601 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
     6661 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
     6721 gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
     6781 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
     6841 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
     6901 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
     6961 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
     7021 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
     7081 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
     7141 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
     7201 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
     7261 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
     7321 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
     7381 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
     7441 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
     7501 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
     7561 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
     7621 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
     7681 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
     7741 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
     7801 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
     7861 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
     7921 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
     7981 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
     8041 aactaagcag ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
     8101 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
     8161 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
     8221 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
     8281 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
     8341 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
     8401 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
     8461 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
     8521 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
     8581 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
     8641 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
     8701 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
     8761 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
     8821 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
     8881 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
     8941 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
     9001 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
     9061 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
     9121 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
     9181 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
     9241 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
     9301 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
     9361 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
     9421 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
     9481 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
     9541 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
     9601 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
     9661 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
     9721 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
     9781 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
     9841 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
     9901 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
     9961 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
    10021 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
    10081 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
    10141 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
    10201 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
    10261 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
    10321 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
    10381 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
    10441 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
    10501 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
    10561 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
    10621 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
    10681 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
    10741 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
    10801 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
    10861 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
    10921 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
    10981 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
    11041 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
    11101 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
    11161 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
    11221 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
    11281 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
    11341 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
    11401 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
    11461 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggaa
    11521 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
    11581 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
    11641 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
    11701 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
    11761 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
    11821 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
    11881 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
    11941 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
    12001 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
    12061 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
    12121 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
    12181 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
    12241 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
    12301 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
    12361 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
    12421 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
    12481 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
    12541 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
    12601 aaaagtctaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
    12661 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
    12721 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
    12781 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
    12841 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
    12901 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
    12961 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
    13021 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
    13081 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
    13141 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
    13201 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
    13261 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
    13321 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
    13381 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
    13441 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
    13501 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
    13561 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
    13621 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
    13681 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
    13741 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
    13801 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
    13861 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
    13921 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
    13981 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
    14041 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
    14101 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
    14161 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
    14221 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
    14281 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
    14341 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
    14401 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
    14461 aactactgct acatcttgcc gaacaggcaa ttgactcatt cctaagatca tcaaaacgtc
    14521 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
    14581 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
    14641 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
    14701 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
    14761 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
    14821 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
    14881 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
    14941 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    15001 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    15061 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    15121 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    15181 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    15241 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    15301 tttatttttc acattttccc attcctaact tgtatacttt tgtgtcatac cccaatgtta
    15361 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    15421 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    15481 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    15541 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    15601 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    15661 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    15721 tcatttctat tgcttcagga aaatcattaa cagatttaga aacagcgctt gaagatcctc
    15781 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    15841 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    15901 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    15961 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    16021 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    16081 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    16141 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    16201 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    16261 gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc tgtggctttt gccgcggctc
    16321 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
    16381 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
    16441 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
    16501 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
    16561 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
    16621 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
    16681 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
    16741 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
    16801 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
    16861 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
    16921 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
    16981 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
    17041 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
    17101 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
    17161 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
    17221 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
    17281 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
    17341 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
    17401 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
    17461 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
    17521 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
    17581 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
    17641 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
    17701 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
    17761 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
    17821 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
    17881 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
    17941 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
    18001 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
    18061 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
    18121 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
    18181 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
    18241 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
    18301 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
    18361 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
    18421 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
    18481 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
    18541 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
    18601 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
    18661 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
    18721 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
    18781 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
    18841 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
    18901 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
    18961 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
    19021 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
    19081 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
    19141 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
    19201 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
    19261 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
    19321 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
    19381 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
    19441 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
    19501 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
    19561 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
    19621 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
    19681 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
    19741 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
    19801 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
    19861 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
    19921 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
    19981 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
    20041 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
    20101 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
    20161 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
    20221 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
    20281 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
    20341 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
    20401 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
    20461 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
    20521 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
    20581 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
    20641 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
    20701 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
    20761 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
    20821 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
    20881 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
    20941 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
    21001 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
    21061 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
    21121 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
    21181 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
    21241 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
    21301 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
    21361 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
    21421 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
    21481 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
    21541 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
    21601 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
    21661 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
    21721 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
    21781 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
    21841 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
    21901 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
    21961 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
    22021 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
    22081 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
    22141 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
    22201 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
    22261 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
    22321 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
    22381 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
    22441 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
    22501 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
    22561 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
    22621 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
    22681 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
    22741 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
    22801 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
    22861 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
    22921 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
    22981 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
    23041 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
    23101 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
    23161 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
    23221 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
    23281 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
    23341 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaaatactg gtttattttg
    23401 gtctcatgta aaactcgctg aaggcctctt cacttataaa tgcttcccca gctgccagta
    23461 cgtctttcat ttggatcgaa tcgatgattt caggaagatc aaataaagtt cgatcgccaa
    23521 ataaactttg cgtaaattga ttggcaatat attcgatcga atttaatgat tggaaatatt
    23581 gtccaagcat tttcttcttc agcaaatcga gatttgtttc tgacacttcc ggatcatcag
    23641 cgaatccaag aatgatttct ttgacttttt ctgctgcttt ctctggttcg tccgtatctc
    23701 cgctgaagtc cgcaaagtga aattcacgat ccaagctgaa ttcaaaacca aagctgtcat
    23761 cgataattcc ttgattgtac atcgctagat agtttcgaga agtattgcct aaaatcattt
    23821 ggaacaacag attgattgct gttttatagc gtaacagttc tgttccttct tgcggcaatg
    23881 tgtctaatcc tttaatacca agtacaaatt tatctcgtgt aatggctgct tccaatgcac
    23941 tttgtttgat gatttctttt gtgttttcag ggaaataacg tacaatttct tgctttggag
    24001 ggaaattttt tgcttcttgg ttttcccgaa taagtttcat caatttctca ggctccatct
    24061 taccaactac aaataaaacc atattgcttg gctgataaaa cgtccgatag cacgtataca
    24121 agtcttgagc tgtgattttg tcgatacttt caaccgtgcc cgcaatatcg atatgcaatg
    24181 ggtgtgtagg atacaagtta tttagtatgc caaaaaacat ccgccagtta gggtcgtctt
    24241 catacatttg gatttcctga ccgatgattc ctttttcctt gtttacagtt tcttctgtga
    24301 agtaaggtgc ttgtacaaaa tcgatcagag tcgtcagatt cttttctacc tgatccgtcg
    24361 tagaaaacag atagctggtt ttcgtaaaac ttgtgaaagc attggcggaa gctccttgtt
    24421 tcccaaataa ttgaaagaca tcaccatctt ctttttcaaa caacttatgt tctaaaaaat
    24481 gggcaattcc atctggaact ttcacctttt ctttttcacc atagggaata aattcgttat
    24541 cgatcgaacc ataattcgta ctgaacaaac catatgtctt gtgatagtca tttttaggca
    24601 acaaatacac ggtcaaaccg tttggcagta cttcatgata aagtgtttca ttgatttgct
    24661 catattctgt tttattcatt tgcatttcct cctgctaaaa agaagattgc ctgcaattcg
    24721 atttgctcag ctacttgttg tatctctttg atcgttacgc tctccatacg tttcaaccat
    24781 tcttcatcag ataattttgt ttccggcagc cagctgtcca aaaaagaagc ttcgattgcc
    24841 gcttgcggag agtctagaga aagcagatat tggtttctca gcattgcttt tgtctgagac
    24901 agttccaact ctgttatttc accatttcgc aaactttcta attgctcgtg aatcagatga
    24961 agtacttgat ttcggttctt ttcatcgata ccggtttgga cactcatgaa tcctcggaac
    25021 gtatccacgc tactagaggc ataataagct agactttctt tctctctgac attcatgaaa
    25081 agtttagagt gaggaaaacc gccaaataaa ccgttaaaga ccattagcgc aaaacgttct
    25141 ggttcatcgt aatacacatt tgtctgataa gctaggttca gctttgcttg aacgattggc
    25201 tcacgtactt gtcgttcctt cacgatattc acttgaggtt gggtataaaa cagatctgga
    25261 taaactgttt cccgcgactc aaatggtaat tgcccaactg cttcagctgc tttgtccgga
    25321 tcaacatcgc cgacaacaaa aatgtcgatt tgatcatttg ccatcatttc ttgatagtag
    25381 gacgctagcg aactagcagt gatcttgtcc aaatcttcga ctacgcccaa ccctgggatc
    25441 ttttgttccg ggctgttttc aaaataaagt tcttgcaagg cataggaagc aaaagtttgt
    25501 ttatcttcct tcaaactttc caaatataga cgcagattgt tcttttccaa gtcaaacgtc
    25561 aactgatcaa actgatgatt tttaatattt ggataaaata aaacctcttt taaaaaatct
    25621 accgcttgag aaaaaaggtt tggatcattg acatattcac cattcacaaa actgatccct
    25681 gcgtttagcc aatgtaaatt tccttttttt ctaactgata atccaaagct tgcgccataa
    25741 agctctgcaa gttgcgcact taactttgtc tgatccggat aattcaaact atttgtttcc
    25801 aacatgctgc tgagaagtga acgtttcgtg atgacttctt gttgcagacg cgcagtaaaa
    25861 cggataaaaa tccggatcgt tttgtattgt tttgttggta agacatgaag attcacgcct
    25921 tctgccaatt gatacaccat atttatatgc tccttttcac agttgattgc ccgcttactc
    25981 ttttaatggg tcaacctgcc ttttttactt attcctctgc ttgaaattta taagttcagg
    26041 caattcgccg ttttttctaa atgatgttac actttatagt atagcataga tgttttttat
    26101 caaaagaaac agacggctaa aagcgtatat tgttttttta ttttttattt ttcgatatac
    26161 taaagacaaa taaaagaagg gagggtcatt catgatcaaa gaattcaaag agttcatcat
    26221 gcgtggagat gtcttggatc ttgctgtcgg cgttgttatt ggtagtgcgt ttacaagcat
    26281 cgtaaaccaa gtggtgcaag gcttgatcac accactaata ggttggtttg tcgcaatgat
    26341 cacaggtact tctgatttag aaggagcact ttcaattctt gactggtcgc cgacaaaagg
    26401 cgtcacattt gcgtttggta acgttattag tgctatcatt acatttctga tcactggttt
    26461 tgtcttattc ttagttgtca aagcggcaaa ccgtgcgaag aatttacgct ccaaagaaga
    26521 gcaagtggaa gtggaagaaa ctcctactgc agaagattat cttagtgaca tacgcgatct
    26581 tcttgccaaa caagtggcag aagacaatac acatccagta gagcaaacaa atctttccga
    26641 tacttctaaa taataaagaa tctaaaaaaa agaaagccga ttttcagtgt cggctttctt
    26701 tttttagatt cttaacttgc tacttgttcc tttttcatgt cgatatgtgg aatatcatct
    26761 tccaaataca catctgagat tgccttgaat ccaaacgact cataaaaagc ttgtaggtat
    26821 tcttgtgcgc cgatcacgat tggtttttct ggaaaatttt tctggatcat gttaatcgtt
    26881 tcttgaacaa tctttcttcc taaaccatct ttacggttgt cctgatgaac aaggacacgt
    26941 ccaaaatgga tactctccgc ttcttcatat actcgcgtgt aggcaaggat cttcccatca
    27001 gtatcttgaa aaaacgtatg ccaagcttgt ccatcaatgt catcaacttc ttgataagga
    27061 cactgttgtt ccacaacaaa aactgcgatt cgttctttga cgatcgcgta aaactctgct
    27121 gttgacaatt cttcaaattt ctttacctga tattccacta agcaaacgcc ccctgctttt
    27181 ttattcttag cataccgatt cgcacacaaa aaagcaaacg aaccttacga atctcaggct
    27241 cgtttgcttt t
//
LOCUS       DAFEEZ010000038        26165 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000038
VERSION     DAFEEZ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26165
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.038"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(119..940)
                     /locus_tag="LP245_001691"
     CDS             complement(119..940)
                     /locus_tag="LP245_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL1519613.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(1037..1315)
                     /locus_tag="LP245_001692"
     CDS             complement(1037..1315)
                     /locus_tag="LP245_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519614.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            1583..3592
                     /gene="metG"
                     /locus_tag="LP245_001693"
     CDS             1583..3592
                     /gene="metG"
                     /locus_tag="LP245_001693"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBL1519615.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(4071..4658)
                     /locus_tag="LP245_001694"
     CDS             complement(4071..4658)
                     /locus_tag="LP245_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519616.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            4833..6155
                     /locus_tag="LP245_001695"
     CDS             4833..6155
                     /locus_tag="LP245_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1519617.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            6310..7086
                     /locus_tag="LP245_001696"
     CDS             6310..7086
                     /locus_tag="LP245_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBL1519618.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            7079..7648
                     /gene="rnmV"
                     /locus_tag="LP245_001697"
     CDS             7079..7648
                     /gene="rnmV"
                     /locus_tag="LP245_001697"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBL1519619.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            7641..8525
                     /gene="rsmA"
                     /locus_tag="LP245_001698"
     CDS             7641..8525
                     /gene="rsmA"
                     /locus_tag="LP245_001698"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBL1519620.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            8976..9605
                     /locus_tag="LP245_001699"
     CDS             8976..9605
                     /locus_tag="LP245_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519621.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(9729..10838)
                     /gene="ugpC"
                     /locus_tag="LP245_001700"
     CDS             complement(9729..10838)
                     /gene="ugpC"
                     /locus_tag="LP245_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBL1519622.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            11047..11469
                     /gene="mgsA"
                     /locus_tag="LP245_001701"
     CDS             11047..11469
                     /gene="mgsA"
                     /locus_tag="LP245_001701"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBL1519623.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            11792..12325
                     /locus_tag="LP245_001702"
     CDS             11792..12325
                     /locus_tag="LP245_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBL1519624.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKNFKKFSDPR"
     gene            complement(12369..14132)
                     /locus_tag="LP245_001703"
     CDS             complement(12369..14132)
                     /locus_tag="LP245_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519625.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(14135..15850)
                     /locus_tag="LP245_001704"
     CDS             complement(14135..15850)
                     /locus_tag="LP245_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519626.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(16629..16853)
                     /locus_tag="LP245_001705"
     CDS             complement(16629..16853)
                     /locus_tag="LP245_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519627.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            17044..19821
                     /locus_tag="LP245_001706"
     CDS             17044..19821
                     /locus_tag="LP245_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL1519628.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            19902..20321
                     /locus_tag="LP245_001707"
     CDS             19902..20321
                     /locus_tag="LP245_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBL1519629.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            20333..20803
                     /locus_tag="LP245_001708"
     CDS             20333..20803
                     /locus_tag="LP245_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1519630.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            20820..21599
                     /locus_tag="LP245_001709"
     CDS             20820..21599
                     /locus_tag="LP245_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1519631.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            21586..22407
                     /locus_tag="LP245_001710"
     CDS             21586..22407
                     /locus_tag="LP245_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL1519632.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            22424..23473
                     /locus_tag="LP245_001711"
     CDS             22424..23473
                     /locus_tag="LP245_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1519633.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            23486..24490
                     /locus_tag="LP245_001712"
     CDS             23486..24490
                     /locus_tag="LP245_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1519634.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            25123..26142
                     /locus_tag="LP245_001713"
     CDS             25123..26142
                     /locus_tag="LP245_001713"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBL1519635.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT         8499 a         4607 c         5328 g         7731 t
ORIGIN      
        1 ttttttattc agaaagttta cgaatacatc aaaattctga aacaaaaaac gtaactcaca
       61 aagagttgtt tttgcgtttt ttcttgaatg attaggtctg aatcttttgc tcacaacctt
      121 attcatggtg ccccggcttg agctgataga tttttgaagg acggccgatt cctacaggac
      181 gttcaccgat ctcatcgaaa tattggagca tagctttctt aaaattggaa tgatcgatcg
      241 ttttataatc gatccctaag aatttagcaa atacttttcg agcttccgta atcgtgaaat
      301 ctttacctaa aacttgtaga acttgcggct cgtgttccat tttattgact acacggttga
      361 atgctttcaa gatgatttga ctatggtcaa aagccaaagt atctttgcca gaagactctc
      421 cagtgactaa atcaagcgag atagccactt ctccgctaga taaatggatc ttgttactat
      481 gacgttctag tgtgaaccag cgtacttcct tggcatcatc tccggcgatt agcggttctt
      541 ctccaataaa ggctaagtag ctgactgtga cgacccagcc tcgcggatct cgattaggcg
      601 tactgaatgt atgcagttgc tcaatatttt cttttgaaat aaccacacca gtttcttcct
      661 ttgtttctct taagacgctt tctccagttg actcatcctt ttggacaaag ccaccaggca
      721 atgcccatga atttcgataa ggatgccctt ttctttggat caacaaaact ttcagctgat
      781 cttcttcttt gttatagcac atcagtacga tatcgacagt caaagagggc ttgtcatatt
      841 ctggacgttc ctgtttttga taccagttaa gaaattcttc ttcacttgct ttatgttcat
      901 aatataattt ttcttcttct ttagaagcaa aacggttcat ctgaccacct ccattgacag
      961 taaaagtact ttttacctta ttgtagcaga ctctgaaaaa aaaccaagga tttacttgaa
     1021 aaatctaggt tatcatttaa atatgaaaaa taaatggaag tatgagattg aataaaaaga
     1081 aaagcagata aaacggcaat actttatacc gctcttcacg aatggcaaag aagccacaaa
     1141 taacgatata tacgtcaatg ataaaacgca aaatccaagc tgctgtcata aaactgttca
     1201 aatgcccatg gaggttaaaa taaccataca tacgaatata aaaatagctg aatattaaat
     1261 gtgctaatga aagaaaagca atactaagtg taaaaaaaag atgtttcttc tgcatgattg
     1321 ttccagtccc ttactaagat agatagtctt tattatacca cgtgtgaggg gagaaataaa
     1381 aagccgtttt ttagtagata tgaaacaaaa caaaaacccg catttattca acctattcat
     1441 ccttttaaag gatagattga acgtagatag aagtcgttta tccagtcttt ttcattttga
     1501 aaaaaagcta acagcatgct ttttttatgg tatactagca aggaaacgaa ttcgcatcat
     1561 gcgataaagg aggaagagcc ccgtggcaga aaaggaaact ttttatatca ctacgccaat
     1621 ctattatcca agcggcaaac ttcatatcgg caactcgtat actacgattg catgtgacgc
     1681 aattgctcgt tataaacggt tgatgggctt tgatgtgttt tatctcactg gagtggatga
     1741 acatggtcaa aaaatcgaaa caaaagcaga agaactaggt gtaaaaccgc aagaatatgt
     1801 agataaaatg gcggctgatg tcaagaaatt atggaaaacg cttgatatca gttatgataa
     1861 attcattcgc acgacagatg attaccataa agcagctgtt caaaaaatat ttgatcgttt
     1921 attagaacag ggagatattt acttaggtga atatgaaggc tggtactctg tttctgacga
     1981 agaattcttt acagaaacac aacttgcaga agtgtacaaa gatgacgaag gtaacgtgat
     2041 cggtggtaaa gcgccaagtg gacacgaagt agaattggta aaagaagaat catacttctt
     2101 ccgcatgagc aaatacgcag accgtctatt ggaatactat gaagaacatc ccgaattcat
     2161 ccagccagaa tctcgtaaaa acgaaatgat caacaacttt atcaaaccag gattagagga
     2221 tcttgcagtt tcacgaacaa cttttacttg gggagtacca gtcaagagtg atccgaaaca
     2281 tgtggtgtat gtatggatcg atgcattatc caattatatt actgcactag gatatggctc
     2341 cgaagatgaa agtctattcg aaaaatactg gcctgcagat gttcagatgg tcggtaaaga
     2401 aatcgttcgc tttcatacga tctattggcc aatcatgctg atggcccttg atttgcctct
     2461 acctaaaaaa gtatttgggc atggctggct attgatgaaa gacggaaaaa tgtctaaatc
     2521 aaaaggaaat gtcgtttatc ctgaaatgct tgtggaacgt tatggtttag atgcactccg
     2581 ttattatttg cttcgtgctg ttccgtttgg gtcagatggt gtctttacgc cagaagattt
     2641 tgtttcccgt gtcaattatg atctggcaaa tgatctaggg aacttattga atcgaacgat
     2701 tgctatgatc aacaaatatt gtgatggact cgttcctgac tatgcctcac ttgtcactcc
     2761 atttgatagt gaactgtcta cgacggctgc taacgttgtc ggacgttacc atgatgcaat
     2821 ggaaaaaatg gaattcaata cagcattggc tgaaatctgg gtgctgattt ctcgtgcaaa
     2881 caaatacatt gatgaaacag aaccatgggt attagcaaaa gacgaagaaa agaaagctga
     2941 attgaatagt gtcatgatcc atttagctga atctttgcgt atcgcagcga tattacttca
     3001 gccaatcatg acagaaacgc cagagaagat cttcaatcaa ctaggattgg actctgaaac
     3061 aatgaatctt gaaggattac actttggcga atttccttca ggaacaaaag tagttgcaaa
     3121 aggtacacca atcttcccac gtttagatat ggaagaagaa gttgctttta ttcaagaaaa
     3181 aatgtctgaa ggtactcaaa caaacgaaga tacagtcaaa tgggatccag aagaaacaga
     3241 acttgtttca acgaaagaaa aacaaatcaa atttgatgta tttgaaaaag tagaactaaa
     3301 agtagcagaa gtcatcaact gtcaaaaagt agaaggggca gataagttgc tgcaattccg
     3361 actagatgct ggagacagcc aagaccgtca aatcttgtca ggaatcgctg aattttatcc
     3421 tgatccaagc gaattgatcg ggaaaaaagt cgtcattgta gcaaatctga aaccacgaaa
     3481 gatgcgtgga caaatcagtc aaggaatgat cctttctgca gaagcaccag atggctcttt
     3541 acaagtaatc gaagcaccaa aatccatgcc aaatggctca gaaatcgcat agaaattcaa
     3601 agggggtatg acactagttg tgtcataccc cctttttccg aaatttgaga agcaattttc
     3661 gtaaattcct tcttattact tgaagccaat catataatac agaaacagag aactatccaa
     3721 aataaatcct agaaaaagaa gtacgagctt cgctgatttt tgttaattta gaataatact
     3781 aataggaatc gtaaaaacag aaaaaaagca taatgataaa gggtcgggca gattttaatt
     3841 gattcatctg gtactctttt ttattgtcct tacattcata aagtttgaat gcaatgactt
     3901 tattacatct atatttatat ctaacagtag cgttgatgtg ttaattataa gttctatcac
     3961 tttatgttca attagtttgt gctcttatat gtgtgattga aaatatagat aaaaaaacaa
     4021 tcatcggctt tgacttcgat gattgttttc tttattttgt aaaaatccta tcacttgatt
     4081 ttatggtaac cttttatttt tgtcttcaaa cggcttggta agagagcagt aagcagtgca
     4141 aatgggatcg aaaagacata ccagaaaatc gtacgtccga taccataatg ttgatagagc
     4201 tttgtcaaca tcacgtgtaa caagatcaac cctaaaagca aggagccagc tataaaccaa
     4261 tgattatccc aatgcatgac ttcactaagt gccatcactc caaaaggata gaaataaaaa
     4321 tagatcccga ctaaggtcat ccgccagttc tttgtaaatg ttccgatatt caataaaaag
     4381 aaaatcgctg aaagcaaaat accgataggc ggaaaaagcc caaccaaaaa ggaatacaac
     4441 atcccccaca agatcatcac aggacctttg atcaatgcaa cgattgcgat gaacaaagtc
     4501 agcaatatta gtttttgtga taacgttgca acagtcatta atccaaataa aattaatgtg
     4561 aaccaatgcc aatgggactg ctgttgttct ttacgggaaa aatcgacccg gttggataaa
     4621 taatctgcta atttcggata agaacgctta aaatccataa actgttcctc cttcgtggaa
     4681 aaggtaggtt tagtatacga aaaataaaaa agaaatacat ccgtcttaag agggagtttt
     4741 tcactgaaag tggagaaaaa agaatggtaa attaaaatat tctcagttat actgaaaatt
     4801 ataccaaatt tcaaagaaga aagaggatgg gaatgaaagg caaactaaaa cgagaaatca
     4861 atctgtttgg cgcattagct accgttatgg gaaccgtgat cggtgcaggc gtcttcttca
     4921 aaactgctgc tgttactgct agtactcagt ctacaagttt gacattgcta gcttggcttt
     4981 tgggtggttt cttaacgatc tgtgctggat tgacagtggc tgaattagct acagcaatcc
     5041 cggaaactgg tggagctgta aaatatattg aagctgcgta tggaaaattg cccagctttt
     5101 tattaggatg ggcgcaaagc ttgatttact ttcctgctaa tattgctgca ttatcgatta
     5161 tctttgcgac acaattgacg aacttattac aattatctac cgattatctt ttgttgattg
     5221 cagtgatcac cgctgtttct gtgacagggt tgaatttgtt agggacaaaa gtcggtgctt
     5281 ctgtacaatc agtgacgttg attgttaaat taataccaat tgctgtgatt gtcatatggg
     5341 gattattgac cccaggacaa ggaactgtcc agttatttcc aatcgaagct ggaaaagatg
     5401 ttacttttgt cgaaggattg agcagtgcgt tgttagcaac gttgtttgct tatgacggct
     5461 ggttaggtgt cggtgcaatg gcaggggaaa tgaaacggcc ggaaaaagat ttgcctaaag
     5521 caattattct tggtttgagt tttgtaacag tcgtttatct attgatcaat tttgtttttt
     5581 tgaaaacttt gccgattgat catcttgccg gtaatttgaa tgcagcttct gaagcatcag
     5641 acgtcatttt tggaggaatc ggtggaaagc tggtcactat tgggatcttg atctcggtat
     5701 acggtgcatt gaacggttat acactaactg ggatccgcgt gccttatgcg atggctttag
     5761 aagacgagct acctttcagt aaacagctga caaagctttc aaagaagttt acggttcctt
     5821 atgttcctgc ggttttccag ttagcagtag cttgtattat gatgagcctt ggttctttcg
     5881 actttttaac agacatgttg atttttgtga tgtggctatt cagtttactg atttttatcg
     5941 gtgtctttat tttaagaaaa aaagcgccgg aattgccacg tccatataaa gtaccacttt
     6001 atccaatcgt tccgattatt gcgattctcg gtgctatttt cattttaggt atgacgatga
     6061 tgacgcaaac gaaattagca ttgatcggta taggtgttac cttgataggt atcccagtct
     6121 attatcaaaa aaagaaaaaa cgctcagaag agtaaaatat ttcaacaaca gacagaaaaa
     6181 gtacgaacta ggtcctctag atcttcgtgc tttttctatt tcaataaaac aagttcttct
     6241 attttgattt ttgctacttc tgcaagtagt gcttatgtgc taaagtaaga atgaaaagga
     6301 gagataaaca tgatatttga ttctcatacc catttaaatg ctgaacagtt caatgaagat
     6361 attccagaaa cgattcagcg agcacaagaa atgggggtaa cgaaaatggc ggtcgtgggc
     6421 ttcgatacgc caacgattga aaagtctttg caattaagcc atgactatcc aaatatatac
     6481 agtattatcg gctggcatcc gacagaggct ggcagttata cgaaagaaat cgaaaataaa
     6541 ttacaagaac aattgacttt accaaaggtt gtagcattag gggaaattgg cttggattat
     6601 cattggatgg aagacccgaa agaagtccaa gataaagtat ttcgcagaca gattgctatc
     6661 gcaaaagaaa tgaacctacc aatcagtatt catactagag aagcacttga agacacgtat
     6721 caaatcctaa aagaagaaga tgttcgagat atcggtggaa tcatgcatag tttcagtggt
     6781 gattatgaat gggcaaaacg atttcttgac ttagggatgc atatttcatt tagcggtgtc
     6841 gtcactttca aaaaagcatt agacgtccaa gaggctgcag caaatgtacc aatcgaacga
     6901 ttacttgtgg aaacagatgc cccttatctg gcaccagttc cttttagagg aaagcgaaat
     6961 gaaccaggct atactcgtta tacagtagaa aagattgctg aacttcggaa tcttccgaca
     7021 gaagaagtgg ctgcccaaac atggacaaat gcgcaccgat tatttggtct aagcgaacat
     7081 ggataagatg aagatccaag agattatagt cgttgaagga aaagacgata caagaaggct
     7141 gcgggaagta gttgatgcag atacgataga aacaataggg tctgcaatca atgaagagat
     7201 cctgatgcaa attgaacatg cccaagagac tcgtggagtg atcgttttta ccgatcctga
     7261 tttttcagga gaaaaaataa gaaaaatcat tatggaagct gttcctcagg caaaacatgc
     7321 ttttttgccg cgcacacaag ctaaaccaaa gaaaaaggga agccttggtg tcgagcatgc
     7381 aagtgatgct gctattttag aagcattgaa aaaggtcgtg acgccagaca tttcccaaac
     7441 ggctgtttct gaaatcacta gacaagacct tttagactat ggtttaatag ctggggcaca
     7501 agcaaaagaa aaacgagaaa aactaggtga cgagttgcgc atcggttaca cgaacggcaa
     7561 acaattggaa aaacgtttga agatgtttcg tattacgccg aaagaactcg cccaagcaat
     7621 gaaaatagtg gaggaacaac atgagtgaat atcgtgaaat tgcgacaccc tctagaacaa
     7681 aagagatttt attgaaacat ggtttttcat ttaaaaaaag tttaggacaa aattttctga
     7741 ctgaaccaaa tattttaagg aaaatcgtag aaactgcgca aatagatgaa catacgaacg
     7801 tgatcgaagt tggaccagga atcggtgcat tgacggaaca attagccaag catgcaaaac
     7861 aagtcgtagc atttgagatc gatgatcgtt tgatccctgt attggctgat acgatgcaac
     7921 cctatgacaa tgtgactatt gtacatcaag atattttaaa gaccgatttg tcaacagctg
     7981 ttagagaaac atttcatgag gagcttccgt taaaagtcgt agcgaattta ccttactata
     8041 ttacgacacc gatcatgatg cattttcttg aatcagattt ggttgtggat gaactagtcg
     8101 tcatgatgca aaaagaagta gctgatcgta tctctgctga accaggaacg aaagcttatg
     8161 gttcattatc gattgctgtt caatattata tggaagccag tttagcattc atcgtaccaa
     8221 aaacagtatt tgtccctcag ccaaatgtag attcagcgat tttgaaactg acaagaagag
     8281 atataccggc agtcgaagtg acagacgaaa aagcattttt ccgattgaca aaagcggcat
     8341 ttcagcaaag aagaaaaacg ctttggaata acttgcagca ttcgtatggc aaagatgacc
     8401 agacaaaagc atggttagca aaaagcttgg aaacagctgg aatcgatcca aaacgtcgtg
     8461 gggagacttt gtcattacaa gaattcgccg cattaagcaa tgcgatgtca gaaaatatgc
     8521 agtaaaaaaa gaggttgtga cagaagttgt gaaaaagctg tcctgcatca agtaataaga
     8581 acagccaaac aaaaatagtt cctcatgttt ttcgtttgtt tgggcttatt accgcagatg
     8641 caagcttttg aacaccgttt aagaaagagg ttgtgggcct gccgtttaac tctaagtcac
     8701 aaggaacaat ttcaaaaaac agcttctcat gtttttgagt tagttggtct tattacttga
     8761 tgcaagcttt tgaccactat tatgccgaac aaggagatgt gacacaaatt ttgtcacatc
     8821 tcctattttt gtttcttgat caaaaaattc ttatacttga tactcacact cattttgtat
     8881 ggatttagaa aagaatatgt gtcttgacag ttattagtaa gtgagttata ctaagtcgac
     8941 atttatgtgt caagacatat taggagagag aaaaaatgag aaaaaattca gttcgaaaac
     9001 taacgatttc tgctttattg attgggatgg gggtcattat cccaatggtc atgcctaaaa
     9061 tcatgattcc accagcttcc tttactttgg cgtctcatgt gccattattt attgcgatgt
     9121 tttttacacc aggagttgca gtggctgttg cgctaggtac gacatttggt ttctttttaa
     9181 caacgccggt tatcatcgca ttgcgagcat tgtcacatct tgtgtttgcg ttgattgggg
     9241 cttggtactt gcaaaagcat ccgagtatcg ttttaaaaaa tggacagttt acttttgcta
     9301 attggcgttt ccaagggttc aattttgtga tcggtgtgat tcattcttta gcagaaatgc
     9361 tagtagtcag catcttttac tttattggta atatgcctga aacatattat tctcaaggat
     9421 atttttatac agtattcatc ttgatgggga ttggtgggct tatccacagt ttagttgatt
     9481 ataatattgc ttattttata gcaggaacac tcagcaaata ttttgatatc cccgtattta
     9541 cggcagcaaa aaaagaaaat cggaaagagt cgattcaagg gtacgcgaag aaaacgacat
     9601 attagacatg atctctcaaa aaaaaaactc tcatctagta atggataata aatcctctaa
     9661 gatgagagtt ttttgtccta aaaagagctg caccaacatc ttctggcaca gctctaacag
     9721 ggggcaattt atggaagttt gatgacttgt tctgtttctt tatcaaagaa gtggcctttg
     9781 ctgatgttga aggcaaggtc gactatttcg cctggtttat ggaaatctct tgcatctact
     9841 tttgagatga actcagtaga accagttttt gtgtaaagca tcgtttcagc tccaagtaat
     9901 tcggaaacga caacttctga tttcactacg gcttcaggtg aagcttcaag ggctacttgt
     9961 tcactgtgga tgtcttctgg acgaataccg aagataactt cttttccttc ataacctttt
    10021 tcaactaata ctttgttttt tccttcagga atacgaagct taagcccatg tccatctgtg
    10081 ataacaccat ttttcaatgt cacattaaag aagttcatgg caggagatcc aataaagccg
    10141 gcaacgaaca tattgacggg tgtatcataa acttctttcg gtgtaccgat ttgttggata
    10201 aatccgtctt tcatgataac gattcggtca gccatagtca ttgcttctgt ctgatcgtga
    10261 gtaacataga tggtcgttgt ttcaagacgc tggtgaagtt tggcaatctc agcacgcatg
    10321 gctacacgta atttagcatc taaatttgat aatggctcat ccattaagaa gacttttgca
    10381 tcccgaacga ttgcccgtcc caatgccaca cgttggcgtt gtccaccaga taaagcagct
    10441 ggttttcgtt tcaagtattc tgtcagacct aagatctctg ctgcattgtc cacacgtttt
    10501 ttgatgtctg ctttatcata tttacgtaat ttcaagccaa aagccatatt atcaaaaaca
    10561 gtcatatgag gatacaatgc gtagttttgg aaaaccatgg caatatcacg gtctttaggt
    10621 gccacgtcat tcatgacttt tccgccgata tttagttctc cttcagagat atcttccagt
    10681 cccgcgatca ttcgcaaagt agttgacttt ccacaaccgg aaggaccaac aaaaacgata
    10741 aattcacggt ctttgattga tagattaaaa tcagttacag aataattttc tgcattgtca
    10801 tattttttat atacgttttt cagagccatt tctaccataa tacgttccac actttctttt
    10861 ttagttttat taactattta aagtataaat gaaagcgtta actaacttca atgtcatgtt
    10921 gaacaagaat tttttctttt ttttgtcaat gtgctagttt taagctttaa taaatatcca
    10981 taagaaataa aaactgatac actggagtaa ataagtatgt taacaatatc aaaaggagtg
    11041 tctcttatga aaatcgcttt gatcgctcat gaccgaaaaa aacctatgat ggtgaaatta
    11101 gcaacagcgt ataaaacaat attggaaaaa catgaacttt ttgctaccgg gacgactggg
    11161 cagaggatca cggaagcaac cggcttgccg atccatcggt ttaaatccgg accgttaggc
    11221 ggggatcagc aaattggagc catgatttcg gaggatcagt tagatttggt gatttttctt
    11281 cgagacccgc tggctgcaca gccccatgaa ccagatgtaa cagcacttat ccgtttatct
    11341 gatgtctatg agattccgtt agctacgaat atcggaacag ctgaggtgct actaagagga
    11401 ctggaagccg gcttcctaga ttttcgaaga atcgtccatg aaatagacaa gcatccactt
    11461 tcattttgat ggataagcgt atggaaaaat aacgtttaat gttcgcctat atgtagctat
    11521 aaaagctaaa caaactgata atatgcgata taatacgaac gtattggata atataaacaa
    11581 taatattagt ttttcgtatt tgcagtaaat gtgaaaatat gctatagttt ctgtgggaaa
    11641 agatcccaaa aataatacag agtagaaaat aaagcgttaa gtgctaagag gatgggatgt
    11701 tgcctcttgg acgaaggacg taatgttcgc ggttttattt tcgcattcgc tgcatgatac
    11761 gatgtagcag ctcttaaagg agatgctaaa aatgaagaaa caccggttag acgcacgtat
    11821 gattgctatt atgggcttat tgattgcatt gatggtcact ttgtcccgac tggtagcaat
    11881 cgagacccca tttattaaaa tcagtgtcac atttattcca caagtgatca tgggcattct
    11941 ttttggtcct ttttggtcag ggataggcgc agttttagct gatttagtag gaatggccct
    12001 cttctcgaaa tctgcattct ttattggatt tacattgaat gcatttattg aaggagcaat
    12061 ctacggattc tttttctatc gaaaagagat cacttggaaa aatgccattc tggctacgct
    12121 tagtgtcacg ctgatcatca acttattttt gacaccatta tggcttgcgt tgatgtacca
    12181 tgtgccattg ttcagctggg tcgtttgggc gccccgcctg ttaaaaacag taatatggtt
    12241 accgattcaa tcaattgcca tttattacgt aggacgtagt attccttaca aaaaaaattt
    12301 taagaagttt agcgatccac gctaaataaa aaacaagcag tcttcccatc ccagaagact
    12361 gcttgttttt attgtgctgt gaattgtgct tgatagagcc gtcggtaata accatctttt
    12421 tgaagcagct catcatgggt gcccatttcg acaatagctc cctgatccat cactaatatc
    12481 tggtccgcat ttttgattgt ggacaggcga tgggcaatca caaaactggt ttttccttcc
    12541 atcattgcta agaaggcttg ttggattttt ttctctgtca atgtatcgac tgagctggta
    12601 gcttcatcta agatcaacat agggggatta ctgatcatcg ttcgagcaat cgtcaacagt
    12661 tggcgttgtc catctgatat ctttaaccct tgaccgccaa tcttagtatc taatttttcc
    12721 ggcaaacgtt ctacaaattc atacatataa gaggctttta gggcatcatt gatttctgcg
    12781 tcacttgctt ccggattccc aaaacgaaga ttttctcgca atgtactgtc aaatagccaa
    12841 gtatcttgta acaccattcc aaaactttta cgtaatgtat cacgttggat agagcggatg
    12901 tcatggtcat cgactgtaat tgttcctttt gttgtgtcat aaaaacgcat cagcaaatta
    12961 acaagtgtgg attttccggc ccctgttttt cctactatag caatggtttg acctggataa
    13021 gcagtaaaat tgaaatcttc gatcaaacgc tgcttggggt cataagaaaa agaaacatga
    13081 tcaaaagaga cttttccttt gatatttttg ggttccaagg cataggcatc tggcaaatca
    13141 ggcttttctt ctggctgatc gatcaaatca aatgctcgtt ctagaccaga aaaagcggtt
    13201 tgcagttgtg tcgtgattcc agaaagttcg ataaatggtt tagaaaactg acttgagtag
    13261 atcgtaaagc tggaaatcac accaacagtg attgacgaac cactcttcaa tgccaatagg
    13321 ccgccaacta aaccaatcga taaataagca aggtgatcta caaaacgaga agacgggttt
    13381 gtcaaggaag aagaaaattg tgcccgttgt cctttttcat atagatcagc atttagcagt
    13441 tcaaattgct gttgactagc ttcttcttgc tgaaaagctt tcacgatttt ctggttaccg
    13501 attcgttcgg tcacaaagcc cgagatatcc ccaataatcc tttgctgtct atcgaaattt
    13561 gtttgtgaag cacgagcaac gatccaactc acaaggaaaa taattggtgt agaacaaaga
    13621 acgaccaatg tcagaagtgg acttagacgc atcataaaaa taaacgaaag aatgatgatt
    13681 gccactccag aaaataattg attgaaggcc gcagaaattg caatggaaat attgtccata
    13741 tcatttgtaa atcgactgac gatatttccg tgggagtttt gatcataata acgaagtggc
    13801 aatcgattca gatgagcaaa tgcatctttt cttaattttg caacggataa gtaagctaac
    13861 cgattgctta acacttggat gagccattga ctgactacgt tgattaaaac gataccaccg
    13921 aatagaataa gtaaatggaa cagtcgattg aagcggacct gtccttctcc aatcatttga
    13981 tcgatacttt gaccaatttg taacgtcatc acaactgttg caatcccatt gatgattcct
    14041 agtatcacag ctagccaaat gtcttttgca taggcagtaa ggtaaggaat gaatcggcgg
    14101 agcgtctgca aggataattt ttttactttc ataactattc ttcctcctgt gatgcgacga
    14161 tttcctgata ttctgctgat tgagcaagta attcttcatg ggtaccctga gcagcaatct
    14221 taccttgatc catcactaag atatgatgtg cttcttgaat agagcggaca cgttgggaga
    14281 taataatcac tgtactgcca agataagtct gtagcgcctt acgcaaatcc aagtctgttt
    14341 gataatccaa cgcacttaaa gagtcatcta aaatcagtaa tgctggcttg gcaatcaaag
    14401 ctcttgcaat cgtcagtcgc tgtttttgtc cgccagagaa atttttccca ttttccatga
    14461 cttttgtatc taaaccattt ggaagctgac ggacaaattc ttctgcctga gcgattttca
    14521 gagcttccca acattctttt tctgtggcgt ctttcttacc ccattgaagg ttttcacgaa
    14581 tagtcccggt aaatagtaca gaagtttggg gaacaagagc aatttgctga cggagatgat
    14641 ccagctgcca agaacgaaca tccattccgt ccattataac tgtaccggaa ctgacatcat
    14701 agaaacgcgg aatcaattgt gtcaaagtcg ttttcccgct tccggttgga ccaatgattc
    14761 caaggactgt atttcgcttc agctgaaatg taatattttg gagagaaaga ccagaatcag
    14821 gagtataacg gaagtcaaca tggtcaaaag cgataattgc ttcagaagaa aaatcgggag
    14881 tagtactgac ctcagcttca agaatcgaat tttctgtgtc tagcacctct ttcacccgat
    14941 ttcctgaagc ttcggcacgt gtgaagatca cgacgaggtt tgaaacaacg atcagtgcca
    15001 aaagcatttg attcatataa ttgatcaaag caagaacttg tccttgttgc aagctaccaa
    15061 tatttacttt gatcccgcca actgtcagca aacagatgat cccgacattc atgatcaagg
    15121 ttgtagcagg tgataatagg gcagagatat tggaaacacg taaataattg ttcgctagat
    15181 catttgtgct tttatcgaac ttctctgttt ctttttttgt ctgcgcaaat gcgcggatga
    15241 cacgaacacc gctaagattc tgactaacgt gttcattgag ctgatctagt ttttcttgca
    15301 ctttttggta gagaggaacg gtttttttga tgataaaaaa taaaatgatt gagaaaatag
    15361 gcaataatgc taagaaaaac agacctactt cccagtcgat cacaaaagcc atgaccactg
    15421 acccgatact taaaaacggt gctctgatca ataaacgaat gaccattgct aaagctagct
    15481 gaagctgatt gatgtcgttt gtcattcggg tgatcaaggt atctgttcca aaatgattca
    15541 actcgttgtg agagaaagta ttgatttttt tgattagctg attacgtaac tctgtaccaa
    15601 atccttgtga agctactgaa gcatagtatt ggcaaatgat agcacaaatc agaccaatca
    15661 cagacatagc gaccatccat aagcccattt caatgatttt tcctcggtca ttcattttta
    15721 gtccattatc gatcaaggaa gccatcatta aaggcaggac aagttcgaag acagcttcaa
    15781 gaaatttgaa gaacgggccc aaaatgattt gcttacgata gtcttttgca taacgtaata
    15841 actgaatcat atgattcctc ctattattta tttgtccaca attgaaaaaa caagtactac
    15901 cacattgtag cttaggaaat ttagaatgaa aagagaacaa gccttttcat aaatgaaagt
    15961 tttattatga agaagcttta gaaattgaat agactatttt ttttaaaaaa aagaaaatga
    16021 gaaaacatgc cagtctcttc attcatagga acgtctattt tacttaattt ttctataaat
    16081 gaattctgca taaaaaatat atcaagtaaa tgtttataga tgaaactcta tttacttctt
    16141 ttttaatttg ttcttgcaat cttttttgct acgtaatttt tgtaaaaaag tgggttgaga
    16201 gaaatctaat tgattttcaa agaaggagta tgaaaatgag aaaaatattt attcgtttat
    16261 tgtgggtact atcttagagg aataaataat agtggagaaa actatggttt ggcgcagatt
    16321 ctatcaggtt tgatggaacg aagacaacct cccgacatca agtcaaaagc tacttgagat
    16381 tttgatctga aaataaaaaa agaaaacaag gtaggaacat caatgtttct accttgtttt
    16441 cgtaatcaat gggaaaaaac taagagtggt gtacgtaatc aataaaaagg atggtgacaa
    16501 cagtacctct ttactctctg aaagcatcat aactcgtttt tcctcattat gccaataaat
    16561 tgttgttata ccacatataa ggatttgtaa tagctaaaaa cagacaggaa agttgaaatc
    16621 tgtgaatctt attttgtatg gaaggattta tagaacgcaa aaatcaagat aaagatgaat
    16681 aaaaatcctg tttcggctat atattgcgta tctacgccaa taaaacgagt ttgttctgtc
    16741 atagccatat aaagcaaagg caaaaataca actacagcga gataagatcc gatgatttct
    16801 cgaaaagttt tccaggaagt atgtttcctg tttttatatt tatccgattt cattgaatag
    16861 tcatagcctc cttattcttt catatgttga aattccagta taaaaactgg aaggaactgt
    16921 acgtttttta gaataaaaat tataagggat aagtaggctg ctgtctataa taagatatat
    16981 ttttcaattc tttattaaag attttattga caaaatgaat ccgttttcta tgatggagga
    17041 ggggtgaata agttgttgaa gaaggaaatt ttatgttact tagagaacca gacagccttt
    17101 ttcgatttag aacatatgaa cgaggtcttt acagcacaaa ggttagctga tcattttggg
    17161 gtaaaaagaa acacagtcag tcattatttg aaccagttaa atgatgagca actactagtc
    17221 aaaatcaatt ctcgaccagt gatttatttc cacaaagaag cttttgaaaa acaatttttt
    17281 aagttacgca cgaattttta tttttctatc gatgatctca aagaggaaca gccttttttc
    17341 gcgcaaccaa aagacttatt ctcttttatg atcggatacg acgccagttt gaaagaaagt
    17401 atcgaacaaa tcaaaacagc tctttactat ccagatggcg gattaccact tttgattaca
    17461 ggcgaaagtg gcacaggtaa aagttattta gttaatttgg tctatcagta ttgtctgctt
    17521 catgatctgc tagaagattc tgcaccattc atcactttta attgtgcaca atatgcagat
    17581 aatcctgaac ttttgactag caatttgttt ggacatgtta agggagcgta cactggtgca
    17641 gaagaaaata aaaaaggggc ttttgaagca gcagatggtg ggatcttgtt tttagacgag
    17701 gtacatcgct taacaccaga aggtcaggaa aaactgttca cctatcttga tcaaggtgtg
    17761 atttatcgta tgggagaacc taatttgtca cgccggatca aaacacgtct cttttttgct
    17821 acgactgaag agattactag tcatttctta acaactttca ttcgaagaat acctatccga
    17881 atcgaactac ctgcacttaa tcagcgtagt cgtaatgaac ggctagaact gatttactct
    17941 ttttttctcg aagaacaaag aaaaatgggg agccctttgt cagtcagtgg accagctttg
    18001 tcacttttaa caagtcagaa attatccgga aacataggag agctgaaaaa tatcgtcaaa
    18061 gtttcagcag caaaagcata tgctgaacag cgtgaacagc ctgaaatcca tgtcacgatc
    18121 catcatttgc aaaaagaact acttgcgcag cctattacta aaaatacagc acagcaagga
    18181 atctatatta cgcaagacca gaccttagag caattaatgg agaagcaaca gcccgaacag
    18241 cagcgaatcg ttaaaagttt tgagcaaatc ctaattgatt tcaagaaaaa taactgtctg
    18301 ctatattctt gcgaaggaaa attaaagcaa gaagtgattc aattatttga ttttttgctg
    18361 tttgagacca gtagacaaga aaaacacgag ctgctggttt attggacaca atctatccga
    18421 gagacctttc gacaaatgga aactgcctat caaatcaaat tcgatggaaa cagtgtctat
    18481 gccttgagtt actatctcta tcagcgaagc actatcaaat ggttaccgga agaacatgat
    18541 attatccaac taatcaaaga attagaacaa caagtttctc agtcttatcc atctagttat
    18601 cactatgtcc aacgaattct ggaattaagt aagatcaaat tagatattga agacacaagt
    18661 atggatcgga ttttactgac gatctatcta aaaaaagcga aatggtcaaa agaaaaacga
    18721 ctgccaaaag cgatgattgc tgctcacggt tatgcaactg ctagcagtat ggcaaatgta
    18781 gtaaatcgtt tattacaaga ggatctattt gaatcatttg atatgccact agatgtcaca
    18841 ccacagcaga ttgcttcaga aatccttgat tattgcgaaa acagcgatgt ttcaaatgga
    18901 ttgatcatat tagtagacat gggatctctg aaagaaatcc atcagttttt taaaaaacag
    18961 ttatccgtac cgcttttgat tttgaataat gtgacgacac ctttagcaat cacagtaggg
    19021 gaatgcctgc aaaaaaatgt atcattagaa gagatagcag aagagactgt tcgacagatc
    19081 cagccagaat ggcgactgct ctatccagag gaaaacaaac ccaaagcact cattactact
    19141 tgcttcactg gaatcggtac ggcggtccac ttaagtgaac tgctagaaaa aagcttacct
    19201 acggcttgtc agttgaaaat catcccatat gaatatcagc aattaaaaga taagaaaaac
    19261 agtgacccat tattttccat atacgaagtc gtaggaatga ttggcaccac agatcctgat
    19321 atcaccaata tcgactatct ttcattagaa gacctcatct cgggggaaaa gatgtctgta
    19381 ctagctgaat ggttggacac tactatgaat gcttcagaga aggaaatatt caatcagcgc
    19441 atcattcgta atttttcatt ggaaaaagta ctggattccg tgactattct agatacagag
    19501 aaggtgatgg gagaaatcga tcattttatg agagaattag aggtgcagtt gaatcgaagc
    19561 atcagcaatc ccaaaaaatt agcgttgtat gtccatgtga gctgtctcat tgaacgattg
    19621 atccgacaaa tgccaatcga aacctatcaa ggattagaga aatggaagca gtgtcaaaaa
    19681 gaagggttat ctgctattaa atctgcgttt agtgtcattg aagagcatta tagtgtcatg
    19741 atccccaatt ctgagattgc ctatatctat gatattttga gtgaagatac agagtttctc
    19801 tcgatagaag aagaattttg aacataagca agttgttgcc actaattttg gcatgcaact
    19861 tgctttttta gtatgtgtaa gtgaaaagag gagatgaaaa agtggataga gaaattatct
    19921 tagcttccca tggaaaattt gcttcaggga tattagattc attagagctg atctatggga
    19981 aaaatcattc tattactgta ttcgattgct atactgatga gaattttgat ttagcggaaa
    20041 cagtaaggca gctttttatg aggtacaaag ataaagaaat cattgttctg acggatcttt
    20101 ttggcggaag tgtcaacaac gaattcttac aatatatcaa tcgggatcat gtctatctcg
    20161 ttgccggatt gaatttgcca ctattgattg agctagtatc tcggttggac gctgaagtag
    20221 agacaactgt tttgatccag caggtgctaa ctgattcaaa aaaaatgatc cagttttgta
    20281 acgagcggct caatcagaaa atagaagaag acgaatttta ggaggaagaa aaatgattgt
    20341 attgacaaga gtcgaccatc ggttattaca cggacaagta gctttttcat ggacacaaac
    20401 aataggcgca gactgtattt tgattgctaa tgatgatgta cctacgaatg agatacgaaa
    20461 gacaacgatc aaattagcca agccacaagg agtcaaacta gtgatcaaat caattgatga
    20521 ctcgattgcc gcgttgaaaa gcggggtgac agataaatat aagttattca tcgtagtgga
    20581 atcgatcgag gatgcatata agctggcaga agcgtatcca gaaatcaaaa ccatcaactt
    20641 aggagggatc aaggcaaaac ctggtactcg cagcatcgga aaagcggtaa atattttacc
    20701 agaagaggag gaacgcttga aacgattaat tgacaaacaa atagaagtag aaatccgtca
    20761 agtaccagca gataaaaaag tggatgtaag agaagttttg taagaaagga agaacctcaa
    20821 tgattgtaca agcagtctta ttaggaattg ttgcatttgt cgcacaatca gaatatgcac
    20881 tagggacatc gttgctttct cgtccgattg tgacggggct gtttacagga atcgtgttag
    20941 gtgatgtaaa aactgggatc attatgggcg caactttaga gttagcattt atcggatcgt
    21001 tctcagtagg tgcttcgatt ccacctgatg ttgtgaccgg tgggatttta gggacggctt
    21061 ttgctattac agctggagcc ggtacagaaa ccgcgctttt actaggtttg ccgattgcta
    21121 cgttgacatt gatattgaaa aatatttact tagggctttt gattccaatt atgaaccata
    21181 aagcagacaa ttatgcagaa gaaggaaatt ataaaggagt cgagcatatg cacttgcttg
    21241 ccggtatcgg tctttccttg atgcttggtg ttgtggtaat ggtttcttat atggtgggaa
    21301 gcaatacgat cggaaatcta ttaaatatga ttcctgactt cgttcaaaag gggttgtcag
    21361 tagctacagg gttgattcca gctcttggtt ttgcgatgct tgctcgtttg ctgatcaaca
    21421 aacaagttgc accatatttt ttcttaggtt ttgctatagc ttcttactta gagattcctg
    21481 tgaccggagt agctattttt ggtgcgattt tagcagttgt ggtagtcaat attatgaatg
    21541 tccgtcaact accacttcaa acaactgcag gggaggtaga agaagatgaa gaattctgag
    21601 atcaaaaaca gcaaaataac gaaaaaagag ctaaatcacg tattttggcg ttcttttcaa
    21661 atggagtttt cttggaatta tgaacgtcag atgaatatgg cttatgttta tgcaatgatt
    21721 ccgattttga aaaagttata tcagtcgaaa gaagaaatgg cagcagcttt gaaacggcat
    21781 ctagagtttt ttaacacgac cccacatatc gttacactga ttttaggaat cacggctgca
    21841 atggaggaag aaaataagga tgatcctgaa tttgatgtga ctgcgatcga tagtatcaaa
    21901 acatctttga tgggacctct tgcagggtta ggagattctt tcttttgggg aactttgcga
    21961 ttgattgcca caggtgtggg tacctcttta gccatgcaag gaaatatttt aggccctatc
    22021 ttgttcattt tgattttcaa tattccgcac attctgtttc gctatctagc aacaggttgg
    22081 ggatatcgct taggaacggg ttttttgaaa aagatccagg caaacggtat gatggaaagt
    22141 ttgacattag gcgcgtctat tattggactg atggtcgttg gagcaatgac tgccacgatg
    22201 atcaccatca atattccttt aaaaatcggt tcaggagaaa atgctgtgac tgttcaaagt
    22261 atttttgatg atatcgttcc aaatatctta tgtcttggag catttggcat agtgttttat
    22321 ctattgaaga aagaagtgaa accattaacg atcttgatcg gactagcttt ctttggaatt
    22381 tttggttcgt ggatagggat tttttaaaaa aggagcagag aaaatgttta cgatgcaaga
    22441 ttatatctat gaagaaaagg aagtactaag tacgatcttg aaaaagaatg atttttcgac
    22501 aagagaacat atgaaaaaaa cagtgaattt actgatctta gcaacgggtt catcttataa
    22561 cgcttgttta gcagcgaagc cagcattgga atcttatggt gatcttactg tcgatattca
    22621 agaacctttt tattttttca attatggaaa actttctcct tcaatcgata ctgtgattgc
    22681 tgtgtcacaa agcgggaaaa gtgcttctac tgttgaagca gtaaaaatga tacaaaaaca
    22741 agggttacct gttgttgcta tcacaaatga cgtgcaaagt ccacttgctt tagaagctgc
    22801 acaaattatt gatttaggtg ccggggtaga atcagtaggc ttcgttacaa aaggctattc
    22861 tgcgactgtt ttacagttac tactcttagg gataggaatt ggaataagta aaaataaaat
    22921 cagcaaaaaa atagaacaag actacatgca acagttgcgc aaaataatca accatttacc
    22981 agcgattatt caaaaaacgg aagaattttt tgatggatat caaagtttat ttcgtttagc
    23041 acagcgtttc gtcaccattg gatatggtcc aaactgggga acagctaaag aagcagagac
    23101 gaaattgact gaaacaatcc gcgttccgtc acaaggattt gagttagaag cttatatgca
    23161 cggcccatac ctggaggcag atgcttcgca tttgctattc tttattgaag gggaaagtgt
    23221 aaataaggaa cgttcgcaaa agttgcaaag atatatgagt cggtacgttg gagagactct
    23281 caccattacc acaaaaaaag caagaaacga gaaaacactt ggattagcaa tagaatgtga
    23341 tgaatatctg tctgtattag cgcttgtcgt tccgtttcaa ctattcgctt ataaaaccgc
    23401 agtagctaaa ggtattgact tgaacaaaaa gatttttgaa gactttgata cagtcttgaa
    23461 aagtaaatta taagaggtgg aaatcatgct gaaattcaat gaagaagaac aaatcaaagc
    23521 aataaaaggc gcactagctt tacgtccgca agtagaagaa atcatcgata aactttatgc
    23581 ggaaaaattt gacgctgtct attatctagg aatcggtgga acgtatgctt cctcgatgca
    23641 agctgtcact tatatgaatg ggaaaagcaa cttgcctgtc tttgtacagc atgctgcaga
    23701 atattacact actggaaaca aaagattaac aaaagattct atcgttattt tgtcctctgt
    23761 taccggtaca actcaagaag tagtgaaagc agtagaacaa atcaagaaag taggagcgac
    23821 actgattgga tttatcgata aagcgaacag taagttgtct cagctatgcg attttgtggt
    23881 cacttatcca gctcctggaa cagaacaaat caaatttttt atggcagcag atcgattgat
    23941 gtatttgaat ggagaattcg aagcttattc agaatactat gaacagctcg aacgttattt
    24001 accaacaggg ttagtggaag cagagaaaaa agcagatgca tttggcttat catttgcaga
    24061 aaaacatcga cgtgatagta tgcattattt tattggagca gggaatcaat ggggagctgt
    24121 ttattcatat gccatgtgtt actgggaaga acaaagctgg cttccatcga aatctatcca
    24181 tgctgccgag tttcttcacg ggacgttaga gatcgtagaa gaaacaaccc cagtcacatt
    24241 atttttaggc gaagatgaac agagagtgtt atctgaacgt gtggctaaac ttttgccaaa
    24301 aatttgcagc aattatacat tgatagacac aaaagactat ccagtagaag gtatcagtga
    24361 aaaatatcgc ggacgtgttt tgtctttctt attgatgcat gtagtgacac aacgcatcga
    24421 tgctcatgtg gagcagttga actgccatcc attagagata cgccgctact atcgtcagtt
    24481 tgattattag gatagactgg ataaaaagaa tataaaaaat aaagagagca gcgataactg
    24541 ctccctttat ttttttaaaa tattggcatc aattacgtta taaaacacat tttttgcatt
    24601 atctacagtt caacttataa tctgtttaat gggacatgtg ggtgccaacc attttttgtt
    24661 atgcaatagt actatttagt tgttgcatgg atccgtagta aaagtccaag tacaacgagt
    24721 tgcgccagtt tacatagcgt tttgtatcca gaatgttgac taaaacaaaa gttcctatgt
    24781 caaccgtcaa cagagacaat ctgtccgttg caggacctga cagatttaga aatgttcaat
    24841 ctgtctctta tgtattttaa atcaatactc actaggagaa gtttcctaac ctcctaatag
    24901 taatgctggt agtaacattg tcaaaactgc ttcctcttag gaacaagcaa agcataacga
    24961 gtgtaaaaat aaaatgtaga ctattgtaac atatcattga ttatttcaag taaaaacgat
    25021 aaaagaagta aacaaacact taaaaacaat ggaaattagt cccaacttta agaaatgtat
    25081 actataatgg aaattatcaa ttatttattt ggaggaatat ccatgaaaca aaaaatcgca
    25141 gttcttggtc ctggatcttg gggcactgct ttagcacaaa cattggcaga aaacgggcat
    25201 gatgtccgta tttggggaaa tgtacctgaa cagattgatg aaatcaataa gtatcataca
    25261 aatcagcatt ttttacctga tttgacgatc ccagaatcga ttatcggata taaagaattg
    25321 gcagaagcag tggataacgc agatgctatt ttatttgttg ttccaacaaa agcgattcgt
    25381 tcagtcgcac aggaacttat tggtaaaatg aatactaagc caatcattat acatgcaagt
    25441 aaaggactag aacaagatac gcataaacga atctcagaag ttttggctga agaaattcca
    25501 gaagaaaaaa gacaggcaat tgttgtatta tctggtccta gccatgctga ggaagtggca
    25561 gtacatgata tcacaacaat tacagctgca agtattgatc aaaaagcagc agcctatgta
    25621 caaaaactgt tcatgaatga ttatttcagg atttatacaa ataatgatgt gattggcgta
    25681 gaaactggtg cagcactgaa aaatatcatt gcaattggtg ccggcgctat ccatggatta
    25741 ggattcggag atgatgcaaa agcagcaatc atgactcgag gattggcaga aatcagccgt
    25801 cttggtgtcg cgatgggtgc caatcctctg acatttatcg gtttgagtgg tgtgggggac
    25861 ttgatcgtta cttgtacaag tgttcattct cgcaattggc gtgccggtaa cttgttagga
    25921 cagggacata agctggaaga agttctagaa aacatgggaa tggtcgttga gggtgtggca
    25981 acgacaaaag cagcagtaga gctagctcaa cagctaggtg ttgagatgcc aattactcaa
    26041 acaatctata atgttttgta taatggagaa gatatcaaaa aagcagcaaa agaaatcatg
    26101 ttacgtgacg gaaaaatgga gaatgaattt tctcttcgtt aaatagatga tcaatagtta
    26161 atcgt
//
LOCUS       DAFEEZ010000039        25646 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.039, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000039
VERSION     DAFEEZ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25646
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.039"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            133..3660
                     /locus_tag="LP245_001714"
     CDS             133..3660
                     /locus_tag="LP245_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBL1519636.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="LP245_001715"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="LP245_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBL1519637.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="LP245_001716"
     CDS             7448..7789
                     /locus_tag="LP245_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1519638.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="LP245_001717"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="LP245_001717"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBL1519639.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="LP245_001718"
     CDS             9146..11566
                     /locus_tag="LP245_001718"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBL1519640.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="LP245_001719"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="LP245_001719"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBL1519641.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="LP245_001720"
     CDS             13000..13737
                     /locus_tag="LP245_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL1519642.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="LP245_001721"
     CDS             13751..14566
                     /locus_tag="LP245_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBL1519643.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="LP245_001722"
     CDS             14579..15226
                     /locus_tag="LP245_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL1519644.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="LP245_001723"
     CDS             15242..15898
                     /locus_tag="LP245_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL1519645.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="LP245_001724"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="LP245_001724"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBL1519646.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="LP245_001725"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="LP245_001725"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBL1519647.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="LP245_001726"
     CDS             18240..18758
                     /locus_tag="LP245_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBL1519648.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="LP245_001727"
     CDS             18865..19365
                     /locus_tag="LP245_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL1519649.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="LP245_001728"
     CDS             complement(19645..20565)
                     /locus_tag="LP245_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBL1519650.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20730..21743
                     /locus_tag="LP245_001729"
     CDS             20730..21743
                     /locus_tag="LP245_001729"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBL1519651.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="LP245_001730"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="LP245_001730"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBL1519652.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="LP245_001731"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="LP245_001731"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBL1519653.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="LP245_001732"
     CDS             complement(23383..24144)
                     /locus_tag="LP245_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1519654.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="LP245_001733"
     CDS             24333..25427
                     /locus_tag="LP245_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL1519655.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(25513..>25646)
                     /locus_tag="LP245_001734"
     CDS             complement(25513..>25646)
                     /locus_tag="LP245_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1519656.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT         8493 a         4442 c         5408 g         7303 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa atagccagtt atttctgctt ttttattttg tttttttata
    25501 ggttatgatt tgtcaaatta agctagaata aaatgcttct tgtacatagc tcaaaaatat
    25561 ttcgattggt gttctgtaat tcaatgattt tcttggaata tgattacgtt gattgctgac
    25621 actggaaata aatgtctgat tcactt
//
LOCUS       DAFEEZ010000040        23819 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000040
VERSION     DAFEEZ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.040"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(45..779)
                     /locus_tag="LP245_001735"
     CDS             complement(45..779)
                     /locus_tag="LP245_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBL1519657.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1106..1516
                     /locus_tag="LP245_001736"
     CDS             1106..1516
                     /locus_tag="LP245_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBL1519658.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1509..2210
                     /locus_tag="LP245_001737"
     CDS             1509..2210
                     /locus_tag="LP245_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBL1519659.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2210..3796
                     /locus_tag="LP245_001738"
     CDS             2210..3796
                     /locus_tag="LP245_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1519660.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3815..4036
                     /locus_tag="LP245_001739"
     CDS             3815..4036
                     /locus_tag="LP245_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBL1519661.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4033..4794
                     /locus_tag="LP245_001740"
     CDS             4033..4794
                     /locus_tag="LP245_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBL1519662.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5174..5683
                     /locus_tag="LP245_001741"
     CDS             5174..5683
                     /locus_tag="LP245_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBL1519663.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5758..6297)
                     /locus_tag="LP245_001742"
     CDS             complement(5758..6297)
                     /locus_tag="LP245_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBL1519664.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6437..7048)
                     /gene="rpsD"
                     /locus_tag="LP245_001743"
     CDS             complement(6437..7048)
                     /gene="rpsD"
                     /locus_tag="LP245_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBL1519665.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7310..8161
                     /locus_tag="LP245_001744"
     CDS             7310..8161
                     /locus_tag="LP245_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBL1519666.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8189..8824
                     /locus_tag="LP245_001745"
     CDS             8189..8824
                     /locus_tag="LP245_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBL1519667.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8844..9617
                     /locus_tag="LP245_001746"
     CDS             8844..9617
                     /locus_tag="LP245_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1519668.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10025..10822
                     /locus_tag="LP245_001747"
     CDS             10025..10822
                     /locus_tag="LP245_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBL1519669.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10800..11213
                     /locus_tag="LP245_001748"
     CDS             10800..11213
                     /locus_tag="LP245_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL1519670.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11197..13842
                     /gene="mutS"
                     /locus_tag="LP245_001749"
     CDS             11197..13842
                     /gene="mutS"
                     /locus_tag="LP245_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBL1519671.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13860..15968
                     /gene="mutL"
                     /locus_tag="LP245_001750"
     CDS             13860..15968
                     /gene="mutL"
                     /locus_tag="LP245_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBL1519672.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15990..16550
                     /gene="maf"
                     /locus_tag="LP245_001751"
     CDS             15990..16550
                     /gene="maf"
                     /locus_tag="LP245_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBL1519673.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16635..18623)
                     /gene="treP"
                     /locus_tag="LP245_001752"
     CDS             complement(16635..18623)
                     /gene="treP"
                     /locus_tag="LP245_001752"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBL1519674.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18846..19559
                     /gene="treR"
                     /locus_tag="LP245_001753"
     CDS             18846..19559
                     /gene="treR"
                     /locus_tag="LP245_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBL1519675.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19636..20082
                     /gene="msrB"
                     /locus_tag="LP245_001754"
     CDS             19636..20082
                     /gene="msrB"
                     /locus_tag="LP245_001754"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBL1519676.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20252..20854
                     /gene="ruvA"
                     /locus_tag="LP245_001755"
     CDS             20252..20854
                     /gene="ruvA"
                     /locus_tag="LP245_001755"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBL1519677.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20867..21868
                     /gene="ruvB"
                     /locus_tag="LP245_001756"
     CDS             20867..21868
                     /gene="ruvB"
                     /locus_tag="LP245_001756"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBL1519678.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21897..22475
                     /locus_tag="LP245_001757"
     CDS             21897..22475
                     /locus_tag="LP245_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1519679.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22527..23009
                     /locus_tag="LP245_001758"
     CDS             22527..23009
                     /locus_tag="LP245_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBL1519680.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23126..23500
                     /locus_tag="LP245_001759"
     CDS             23126..23500
                     /locus_tag="LP245_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519681.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7774 a         4284 c         5115 g         6646 t
ORIGIN      
        1 ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc cataaataat
       61 aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac tggtacccat
      121 gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg tacaagacgt
      181 ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag tgaagcaact
      241 aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc ttggaagaat
      301 ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa gaattcattg
      361 acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc taacacatgg
      421 tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat caattgtcca
      481 atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca agggaataga
      541 ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct gattccacca
      601 aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag catccagtca
      661 ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt acctagaacg
      721 attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga gtaatccata
      781 aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg aaaagcatcg
      841 gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat aaaaaaatga
      901 attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt taaaagttct
      961 ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt tttctcaaaa
     1021 attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta gtaaaatgaa
     1081 agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca ttattatttt
     1141 cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc ctggaagtat
     1201 cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc ctgaaaaaat
     1261 cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc ctgctggtgt
     1321 aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac tgggagcagt
     1381 cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag gtgtagaagc
     1441 tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg aaatggagga
     1501 gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg actttaggag
     1561 tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg aatcctctcg
     1621 tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc tataaagact
     1681 ataatatcgg gggcaatttt ttgactatgc tgattactcc tgcgacagtg gcacttgcca
     1741 tccctcttta taaaaacttc cgtttactga aagagaattt ttatcctgta atggctgcga
     1801 ttttagcagg aatagtcgca aattgcttgg ttagtgtagg gttcggttac ttcttctctc
     1861 ttcataaaga gatggtgatc tcattactac ctaaatctgt aacgacggct atttctgtcg
     1921 atttatctca tacgatgggc ggggtgaatg ccgtgacact tgctattgtt gtctctacag
     1981 gtatttttgg ttcgctgatc gccactcata ttttccgcct attcaagatc gaaagtccag
     2041 ttgctcgcgg tgtggcgtta ggaagtactt ctcatgctat tggtacagca aaagcaatcg
     2101 agattggtga aatagaagga atcatttccg gacttgcgat atgcgtcaac ggaatattga
     2161 ccgttttatt gctaccgtta ttctttcagc cttttgctgg cttgttttga tgcgaaaacc
     2221 actattttat gctacaataa ccaaaacgtt cgagcataaa aaaggaggga aagacgtgta
     2281 tttgtcttcc gagtatctta aacaatttga taaagatcta tattataaga ttctcctcct
     2341 agaaagtttt gaggatcaag cttggcatac cgctgcacaa ttagcgcaag ttgttcagct
     2401 ggatgcccgc agcgtgtcga aatacctgaa cgagctgtct aaaaactatc agcagtttag
     2461 cggtaagaca caccctttgt ttacaaaaaa tcaccgttct ggttataact tttatgatac
     2521 gctcgattca attgaacatg agcgtttttt gatctatctc gtgcaaagta cgctgaaatt
     2581 ccagttgctg cacgacattt tttttgaaga attccataca atgtaccaat ttgcgcaaaa
     2641 gcattacatt agtgaatcta ctgctcatcg aaaaatcaat gaatggaaac agcaactgca
     2701 aacttacgga attcggctgc aacgaggtac atatatcgct caaggcgaag aagaaatcat
     2761 tcgactttac ttgcatatga cattctggca gttgtttcga gggaaaatct ggccatttga
     2821 aacgatttct caaatggacg taaagaatat ggcagaacat atcatggctt tttttaatgt
     2881 tcgtctgaac gagatcaaaa aaagacgatt ggaatatatg ctaggtgcct tttttttaag
     2941 aaaatcacag aagcattatg ttgtattgaa tgagaaaaaa agacggctga tttctgacaa
     3001 tctgttgttc cagcgatttt gccaggtcat ggagccggta tttcctaatt attttcaagt
     3061 agaagacgag ttaggcgcat tatttcttgt actgatgact cgtgaagaat attatagtga
     3121 tcctaagata cggaagaaaa tttttgattt tcatcaacaa gcaaaaacac cgccctttac
     3181 agccctttca gaagcaaaag ccgctctttc tctttatcag gaagagcagg ggctgccagc
     3241 agaaaatcta accttcgagg cagaaaacta tttattcagc agtcattttt tcgcctatct
     3301 ttttcctaat gcgaaagaaa cgattgatgg caatagtagt gattttatta atcatttagt
     3361 tattgaaaac aaggaattga aacaatggct cgtacatttt tttgaaagta gacacaaaca
     3421 tcccaatcat ctggcattta aaaatcatgc gtttttgatg gggcggtatc tgactgtgtt
     3481 taaaacatta ggagccttta ctccacagct tccaaagatc acgatccttt taatgacaga
     3541 tttcccatta tttgaagagc aactgttaga ggagggatta cggacatttt tccgtaatga
     3601 gtatcagctg atttttctgc caacagatta tcgggggaga gaagttgatc ttctgatttc
     3661 gacaagtaaa gtccaccgca aaccatgggc ggatcttgac tattttattg tgactgaaga
     3721 actaaaatta attgattaca tccaactatc tcaaaaattt gaaatgattc aaaaacaaaa
     3781 actattaaaa caataacaaa gaaggagaaa aaagatgaca tttgaagaaa ttttaccaga
     3841 attgaaaaaa ggtgcaaaga ttattcgtaa aggatggagt ggatttgaac tttatgttgt
     3901 tctcgtatcc gatgatgaat ttgatggctg tccggtgacg ccgtacttat tgatcaaaac
     3961 aagtgacgaa ggtttttcca gcttcgctcc tacagtttgt gatattttag cagatgattg
     4021 ggcgatcgta gaatgaaaaa ccagtatcca gatctagcta aacaggttgt atttatcaca
     4081 ggagctgctt ctggaattgg tgctgcgcaa gcccgagcgt ttcttgaaca agatgctttt
     4141 gtatttggat tagatcaaaa gttcggtaaa atggaagaaa tttctttgcg atttcctgaa
     4201 acttttgcct acgcactagg tgatgttcga caaatgaaag aactccaaca agcggtatcg
     4261 aaatgccaaa atcattttgg tgaagttacg attttactga atacagcggg gatattggat
     4321 gcctacaaac ccttgatgga aactgacgaa tcgctgtggg atctgattta tgagacgaat
     4381 gtgaaaagca tgtatcagct gacaaaaatc atccttcctg atatgatccg ccaaaaaagc
     4441 ggaacgatca tcaatatggc ttcgattgct ggcttgattg ctggtggagg tgggatcgct
     4501 tatacaagcg cgaaacatgc gattgtcgga tttaccaaac aactcgctct ggattacgca
     4561 ggacagggta tccgagtaaa aggaattgct ccaggagcca tccaaacacc aatgaatgcg
     4621 gctgattttg aagggaaagg tgagatggca gagtgggtgg caaatgaaac accagtcaag
     4681 cgatgggcac agccggaaga agtagctgag ctgacgttat ttcttgcctc tcctcaagca
     4741 agctacatac aaggaacgat catcccaatc gacggcggat ggttgttaaa ataaccttgt
     4801 gtttttttca agcttctgta tgataaaact aaagagagaa acaacggttg atgataaaaa
     4861 aagtcgatga ctgttcccga cattcgatgc cgaacagcca gttcaaaaaa ttctttttaa
     4921 taatcgttaa tattcgaaac taagcggctt ttcacgacct cttgatataa acgatattca
     4981 aaagcttgca actgcggtaa caagtccagc caaatgaaaa atataaggag ctatttttat
     5041 ttgaccattc ttattacttg ttgcagggca gctttttcac taccttctgc gacacttcag
     5101 ttggaatttt cttcccatcc tttggtcgcg gtcattacca agataaaatt atcttgcaaa
     5161 ggagaaatag aacatggaaa aaaataatac ccgttcagcc aaacgctgga caacgacaga
     5221 tgtgactcgg atggcgctag tcactggttt atatgtggca gtgacgctgg ttttgtctgt
     5281 ctttagcttt ggagtgattc agattcgtct ctcggagatg ttcaactatc tgtccttgta
     5341 taacaaaaga tacatcgtcg cggtaacagc gggagtagct ttggctaata ttgcttctcc
     5401 tcttggactg atagatgttg cagtaggaag cgtcagcacg ctgcttgtat tgcttatcaa
     5461 ctataaaatc actagtcgca tcaaaaacat gaaaatcaaa atggccgtga cagcatgcgt
     5521 atttgctttt tccatgttta cagtagctgg tcagctaacg attttatatc aactaccttt
     5581 tttcttgaat tggtgggtga ttgctttagg agaattggca tcaatgattg tcggtgggat
     5641 aattatttat tggatcggta aaaaagtgga tttgtcaaaa taaagatctg tttaatttaa
     5701 aatagggcag catggaagag actgaatgtt gagtcttctt ccatgctgct tttttgatta
     5761 atttgtatga agaaatcgat ttagccgttt tttcatcaag ataccgatat aagctgctcc
     5821 agttgccttg attgcttccg gcagtaaaaa cggcagtagt ccactggcaa atgcagttgt
     5881 aaaagtaaga tcaccactta ttttcagcca gatcgttccg cagatcaatg cagcaagaga
     5941 gcccattaga ttggcaaaga ttgcatataa gtaatgagca tccgttcttt cgatcatcca
     6001 accagttatc cacgtttgta agagaaatcc aatcaaatat ccgccagttg gcccaaataa
     6061 aacagctata cctccagtca tccctgaaaa tacaggaaga ccaatcaagc caagtaaaag
     6121 ataaactcca acagatatca atcctagttt tcttccgaga aaagttgctg ttaatccaat
     6181 agcaaatgtt tgccctgtca aaggaaccaa accaaaagga atggtcatct gagaaaggac
     6241 agaaataatc gcggcaaatt ccgcagcaag tatcaattct ttcaatgttc ggttcataac
     6301 gccctctttt cgttaactta atatttttat ttggttaacg aaattgtaaa acaaagtgat
     6361 tactttgtaa atagaaaata taaaaaaaga ccagctatcc aatagatagc ggtctttttc
     6421 aagaaagctt ttgaaattat aagctttggt tgtagtattc aacgacaaga gcttcgtcga
     6481 tttctggata tagttcgtca cgttctggta aacgagtcaa tgaaccttcc aatttttcag
     6541 cgtcaaagct tacgaatgct gggcgtccaa cagttgcttc tacagcttct tttactgtta
     6601 cgatgttttg tgatttttca cgaactgaga tcacttgacc cacttctacg tggtatgaag
     6661 ggatatcaac gcgtttgcca tcaactaaaa tgtgaccatg gttaactaat tgacgtgctt
     6721 gacgacgagt cgttgcaagt cctaaacggt aaacaacatt gtctaaacgt tgttctagta
     6781 agatcatgaa gttaacacca tgtttacctt ctttgatttt gctagctttt acgaacaagt
     6841 tacggaattg acgttcgttc attccgtaca tgtgacgaag tttttgtttt tcagttaatt
     6901 gcatgccgta ttctgattgt ttgccacggc tattaggtcc atgttgacct ggtgcgtaag
     6961 ggcgacgtgc taattctttt cctgtgcctg acaatgagat gcctaagcga cgagaaattt
     7021 tccatgatgg tcctgtataa cgagacatta aaatttcctc caatgaatat aagtttttgg
     7081 agtaaaataa tccgttgaaa aattcataat catatagttt gttcttcaat cttcaccttt
     7141 gcagccgcgg ttacacaatc gaacccgaga cggggcaaca aactagggat gagttattat
     7201 ttttctgctg cattatttta cacaaattac agtatatgat agatcatcca cgaatgtcaa
     7261 gataattagt acataaaaac gctttacaaa cctaggctgt ctttataaaa tgagagggta
     7321 tgtgcaaatg gaaaaaagcg aaggaagttt aaggagaaaa tcaatgaatc cggtatcacc
     7381 attatttgag aaaatcgatg cttcaattga aaagaaggcg aatctttttg aaaacagctt
     7441 ttcacgttac gctgttcgag cggttctcgc ctgtttgttt ttgactttag gaacggctgt
     7501 ggcatttgcg atcgcgatga agggggaaga tatcgcgcat ggtctaggaa agattttata
     7561 cgcatttatg ttcagctggg gtctggtcat gattctatac atgaacgccg aattaggaac
     7621 atcgaatatg ctttatatga ccgtgggtgt ttttcggcag agacttgctt taagtaaggc
     7681 agccaagatt ctatttgcct gtattttttt caatatgatt ggcggtatat tatgtggatt
     7741 tctaatttct atgactacgc catttcaaga tttaacgttg gacaacttta tgttagaatc
     7801 aatagcagta aaactagcaa aaccttcagc aacgattttg gtggaaggga tgtttgcgaa
     7861 tatcgttgtc aataccgctg tactgatcag catgcggatg aaagaggatg tcggaaaagt
     7921 gatcacagtc gtattcatca ttttcatttt tgctttttta ggatatgaac acgtgatagc
     7981 gaattttcct gcctttacgc ttacttactt tgcttctcac ggacagatgg atggaatgac
     8041 agtcagcaat gtgttacata atttgttttt tgctttggca ggaaattata ttggtggcgg
     8101 tttagtaatg ggactgggat atgcttggct gaatcagtca aaatcatcct atgtggacta
     8161 aaaagtcgtt cattaaaggg gaagtgccat ggaagtttta gtttttccaa aaaatgagga
     8221 aaaagcgtta caaatggaaa agtacatgaa aaatcttttt tcctttgctg gagtacctaa
     8281 gccggaacgc gctcttttac aacaaccgtt actggatgag agcaaaaatt tatctatttc
     8341 tgaagtttta gcttttgttc attattatta tgaacaaatc gaaagagagt atcagtatgt
     8401 agcgatcgat ttagtccaga aaaacatcaa acggcttaca tttgaagact tagtcgtatt
     8461 gttgccacta gttcagaaaa aagaatggtg ggacagcatc gactcttgga gaaaagtata
     8521 cagcacatgg tgtaaagcct acccagagca gcgtgaagaa gtctttcaat tgtttgaaaa
     8581 aaaggaagat ttttggctac gtcgaatagc aatcacgttg caattaggtt ataaacagca
     8641 aacagacaca ggactattga tccgagcaat agacgaagat cgtcaaacaa aggaattctt
     8701 tatccaaaaa gcaattggtt gggcattacg cgattatagt aagaccgatg ccgattgggt
     8761 aaaaagacag ctgacaacag atttgagtaa gttagctgtt cgagaggcaa gtaagtattt
     8821 ataagaaagc gagacgacaa gagatgagac gcaaattatt tgcttttgat attgatggaa
     8881 cgttgttaga ttcaaacaaa caagctttag atagcacaag agaagcattg gaaaaattac
     8941 gcaaagccgg tcatctggtc acgattgcta cagggcggag ccgatttcat gcgcaagaga
     9001 tcattcgcga tcttgatttt acgaactaca ttttatgtaa tggagcggcc ggttttttag
     9061 accatgaaca agtatataag aatttactag atcgcgacca gttggatgcg ttcgttcaag
     9121 aagcgcatca tgagcagatc gatacagctt ttgtcagctt agacaatatc aagcgttctt
     9181 cttccaatga tgtaacggtg atggaagaag cgatgcattc tttcggtgct gtcttgcctg
     9241 aattagatca gttttttgca gaggaacaag aaatatacca agcgttagca tttttcgatc
     9301 aaacatatga tgggaagttc tcttcatatg ataaaattcg atttgtccgc tggcatgaga
     9361 acagtgtaga tgtcgtacct aaaaatggtt ctaaagcagc gacaattctg cacttagcag
     9421 aacaagtagg catccctcat gaagacatca tcagctttgg cgatggacaa aacgaccgtg
     9481 aaatgttgcg catgtcagga attgggatag ctatggggaa tgctgtgcca gaagtacaag
     9541 cagaagctaa gatggtcact gatacaaacg atcaggatgg aatttggaag gcattgaaag
     9601 agttaagcgt gatttaaaag aggttgtgaa aaagctgttc tgcatcaagt aataagccca
     9661 gccaaacaaa aatagctcct cctatttttc gtttttctgg gcttattacc gcagatgcaa
     9721 gctttcgaac accgtttaag gaagaggtcg tgacagaagt ggtcagtttc aagaaataag
     9781 aagggattta cgaaaattgc ttctcaaatt tttgtaaaat tacggcttat ttctgaagaa
     9841 gtagatgaaa caacgtttat tcgggaaatg ggactgtgac aagatgtttg tcatagtccc
     9901 atttttttat tttatttttc aaaactaaga aataccagga aagagttcct tttgtttgac
     9961 cttttctttc ttattgaaaa caactataat atagagtgat gttaaaagag aagaggaatt
    10021 tagtgtgcgg gtattgttta ttggtgatgt agtaggttca atgggacgag agatgattac
    10081 tgaatatctt cctagattga agaagaagta ccgtccgcaa gtaacgattg taaatggtga
    10141 gaatgccgct tctggacgtg gaatcacaga aaaaatctat aaaaaatttt tgcaagacgg
    10201 cgtagatgtc gtgacgatgg ggaatcatac gtgggacaac cgcggaatct ttgagtttgt
    10261 aaatgaagct aaaaagatgg ttcgtccggc aaattttccg gaagggacgc ctggacaagg
    10321 gatggtcttt gtcaaagtga accaagtcga actggcagtg atcaacatgc aggctcgttc
    10381 ttttatggtg gacttggatg atccttttcg taaaatgaat gagctggtag aagaagccag
    10441 aaaacgtacg ccgatcattt ttgtagattt tcatggagaa acaacaagtg aaaaacaagc
    10501 aatgggctgg tttttagatg ggaaagtttc agcagtggtc ggtacacata cacacgttca
    10561 gacaaatgat gcgcgaattt tgccaagagg aacagcgtat ctgacagacg ttgggatgac
    10621 aggtccctat gatggtattt tgggtatgcg cagagaacct gtaatcgaaa agtttctgac
    10681 tgcattacca aaacgttttg aagttgtgga acaaggccga tcgattttaa gcggctgtat
    10741 cttggaattg gatgatacga caggtcatgc aaaagaaatc cagctgattc agatcaacga
    10801 tgatcgaccg ttcatggagt agaaagagag gcagtttttt gcagcaggag ccggaaattc
    10861 aaaaagaagt aaggaaactg acaaaacttt taagagagaa tgaaacgatc attcgctaca
    10921 aagaacttga agaaaagatc cagcaaaacc agtatttagc tgagttgaga gaaaaaatca
    10981 aacaagcgca aaaagatgct gttcattttg cccactatga caaaccagca gcagaaaaag
    11041 aagcaatcaa acaagcggat caattcatgc aagaatttga tcagcatccg cttgttgtag
    11101 cttatagaaa acagctgttg gaagcagatg atctgcttca tcatttaaca actatgatac
    11161 aagaagaaat caatggacaa atagaggagg aaaaacatgc ctcaaaaaac taaaaatact
    11221 cctatgatgg aacaatatct aagcatcaag gcccaatacc aagatgcttt tttgttctat
    11281 cgtttaggag acttttatga actattttac gaagatgcga tcaaagcgtc acagcttttg
    11341 gaattaacgt tgacgagcag aaatcgaaat gcagaagaac ctattcctat gtgcggtgta
    11401 cctcaccatg cagcacaagg atatatcgat gccttgattg aaaaaggcta taaagtagcg
    11461 atttgcgagc aggtagaaga tccaaagacg actaaaggga tggtcaagcg cgaagtgatc
    11521 cagctagtca ctcctggtac agtcatggac agcaaaggat tgtcggcaaa agacaacaat
    11581 tttttaacag ctgtagttag tcaaggaaat gaatttggct ttgcttatgc cgatttaagt
    11641 acgggagaat tgaagacggc tcggttgcat gatgaagaag ctgttttaaa tgaagcctct
    11701 gcattgcaga caaaagaact cgtattaggc agtgagatca ctgataccct tcgtgaacag
    11761 ctaagcgggc gtttagggct agtcttttct caacaaaatg agatggaaga aaacgcggaa
    11821 tttagctttt tgacaagcga actagtcgat ccgctggaaa aagaagcaac cggcaaacta
    11881 ttgacttatt tatcggtgac acaaaagcgg agtttagctc atatccaaaa agcagtagaa
    11941 taccaaccag atcatttttt gaaaatggat tattattcaa aattcaacct agaattaagc
    12001 caatctattc ggactgggaa aaagcacggc actcttctat ggttgttaga tgaaacaaaa
    12061 acagcaatgg gtggccgttt actaaaacaa tggctagacc gtccgcttat ccaggcaaaa
    12121 caaattaaag caagacaaga aatggtcgct tctttgctag acagctattt tgaacgtatc
    12181 gatttgcagt cagcattaac gaaagtctat gatctggaac gcctagcagg tcgagtagct
    12241 ttcggtaatg tcaatgggcg agacttgatc cagctgaaaa cttctttaga acaagtgcca
    12301 atgatcagag ggttgattga aggaatcgat caaggtcaat ggcaaagtct gctttcagaa
    12361 atgcagccga tggaccatct cgtccaattg atcgaccaag ctatccaaga tgatccgccg
    12421 ttacaaataa cggaaggaaa catcatcaaa gatggattca atgagcagct cgatatgtac
    12481 cgttctgcta tgagaaacgg aaagaaatgg ttggcagaac ttgaagcaaa agagcgtcaa
    12541 gaaacaggaa tcaagaactt aaaaatcgga tttaaccgcg ttttcggtta ttatatagaa
    12601 attacaaaag caaatcttgg aaatgcagaa ctggagaagt atgaacgaaa acaaacttta
    12661 gcaaatgcag agcgtttcat cacaccagaa ctaaaagaat tggagacaca aatcctcgaa
    12721 gcagaagaaa aatctgttga tttagaatat cagttgtttt tagctgtgag agaagaagtc
    12781 aaaaaggcta tccagccgct acaagtactt gcaaaagcaa tcagtgcagt agatgtgcta
    12841 caaagttttg caacgatcag cgaacgctat cagtatgttc ggccagaact tgtcagtgac
    12901 aagcatcagc ttctgatcaa agacggacga catcctgtag tagaaaaagt attaggacat
    12961 caggaatata tccctaacag cgtagaaatg gcagaagacg aaatgatctt gctgattaca
    13021 ggaccgaata tgtctggtaa aagtacgtat atgcgacagt tggcattaac tgttctgatg
    13081 gcgcaaatgg gctgtttcgt tccggcaaaa caagcagttt tacctatttt tgatcggatt
    13141 tttacccgaa ttggtgcaag tgacgactta attgctggac aaagtacttt tatggtagag
    13201 atgatggaag ccaatcaagc cctgcgttat gctacgccaa acagtttgat tttgtttgac
    13261 gaactagggc gaggaacagc aacctatgac ggaatggcgt tggcccaagc aatcatcgaa
    13321 tatatccatc gtcatgtaca agcaaaaaca ctcttttcta ctcattatca tgaactgacg
    13381 gtacttgaga aagaacttcc gcagcttaaa aatgtccatg ttggagccgt tgaaaaagac
    13441 ggagaagttg tcttcttgca taaaatgatg gatggacctg cggataaaag ctacggcata
    13501 catgtggcaa agatcgcagg attgccttcc aatctactag aacgagcagc agatatcctg
    13561 catacgctag aaaatggcga taacggacac catactgttc cagctgaagt agaagagaaa
    13621 actaaaacag ccaaacagga gcaaataaaa ccacctgcag aaaaagtaaa tcaagaccat
    13681 atacaagacc gtgtaaaaga agaaaaccaa cagctttctt tattcagtga attatccgaa
    13741 aatgaaacag aagtcattga atcactgaag caaataaatt tactagaaat gacgccaatg
    13801 gatgcactaa acacattata tgaattacaa aaacaactgt aggaagaagg cggatatcga
    13861 tggccaaaat ccaagaatta tctgaacgtt tagctaatca gatcgctgcg ggagaagtag
    13921 tggagcgacc agcttccgtt gtgaaagaat tagtggaaaa tgcaattgac gccggcagta
    13981 ctcagattga tatcttagtt gaagaagcgg gactgcggac gatccaagtg attgataacg
    14041 gagaaggcat tttggcagac gacgtagaga atgccttcaa gcggcatgcg acaagtaaga
    14101 tccataatcg cgacgatctt tttcgcatac gaacgctggg ctttcgaggg gaagctttgc
    14161 caagtattgc ctctgtttct gaaatgactc tggaaacggc gaatcaggaa gaaaaacaag
    14221 gcacctatct gtcgctgaaa ggcggagaag ttattgagca tcgaccagca ccactgcgtc
    14281 aaggaacgaa gattaccgtc agcaatctgt ttttcaatac gccagcccgc ttgaaatacg
    14341 tgaaaacact gcacacagaa ttagcgaaca tcggggacat cgtcaatcga ctggcattga
    14401 gtcatccatc gattgctttt cgtttagtac atgatggaaa caaaatgctg gcaactgctg
    14461 gaaatggcga tctgaaacaa acaattgcgg gaatctacgg attatctacc gcaaaaaaaa
    14521 tgctgaaaat cgaaggaaaa gatctagatt ttgagttatt tggctatgtt tcattgcctg
    14581 aggtgactcg tgccagtagg aattacttat cgacgatcat caatggacgt tttatcaaga
    14641 acttttcctt gaataaagca atcgttgcag gttatgggtc aaaattaatg gtcggtcgtt
    14701 tccctattgc tgtattggaa atcaaaatgg acccgctttt agtagatgta aatgttcatc
    14761 cgacgaagca ggaagtccgg ctgtcgaagg aaaaagaact aacagagcta attagtaacg
    14821 ccattcaaaa agcattgtct caagaaaatc tgattccaag tgcagcggat aatctacggt
    14881 ttaagaaaaa agtacctgat cagcctaaaa cagaacaaat cgaaatcgat ttgtcctacg
    14941 cttttgaaga agaaaaacct aaaaagccaa gtagtttgaa ttttgatcga gagacaggta
    15001 cctttttcgt agaagaacta aagaacacat ttgttgacag aattgttgat aagtctgtgg
    15061 aaaatgttga aaactattct ggtttttctg aagaaaacac cacttatcca gaaaaaacag
    15121 cgaaaacggt ggataagttt ggtgaaaatg ttgataactt tgtagaaaaa acagtggaaa
    15181 aatctgaaaa gaaagaattt cccattgtgg ataacatgga gaaaacaaat gaagaacaag
    15241 cagataaatc cgtagaagag gatgaaaaga tttacgagga agaattgaca ctccatcctg
    15301 aatttgattt cactcaagga aacgacaaaa cattagaaca agccatcaag aaattagaaa
    15361 cggaaaaacc agtacaacgt tttcctcagt tggaatattt tggacagatg cacggaacgt
    15421 atctttttgc ccaaagtagc gatgggttgt acatcattga tcagcatgct gcccaagagc
    15481 gcattaagta tgaatatttc cgggaaaaaa ttggggaagt atctgatgat ctgcaagaat
    15541 tgcttgttcc atttgtgtta gactatccaa acagtgatgc tttgaaatta aaagagcaaa
    15601 aacacttgct agaagatgca gggatttatt tagaagaatt tggtcaaaac agctttattg
    15661 tacgggccca tcctacttgg tatcccaatg gagaagaaga atcgattatt cgggagatga
    15721 tcgatatgct gctgacaact ggaagtgtga gtgtaaaaaa attccgtgaa gcaacagcaa
    15781 tcatgatgag ttgcaaacga tcgattaaag ccaaccatta tttgaatgaa gcacaagcac
    15841 gtgtgctgct gaaggatctg gcacgatgcg aaaatccttt caattgtccc catggccgtc
    15901 cagtattgat tcactttacc aattcggata tggaaaggat gttcaaacga atccaagacc
    15961 cgcattaagt caaagagaag agggaaaaca tgaagattgt attagcatcc caatcaccaa
    16021 gaagaaaaga gttattggct catatcgttt cagaattcga gattgaacct gctgatatcg
    16081 atgaaacgcc atttccagac gaacagcccg tcgattatgt tcgtagaatg gctgaagaaa
    16141 aagcacgaac tgtctgggaa caagatgaaa aagaagacca tttagtgatt gccagtgaca
    16201 cgactgttgt tctcaatcaa gagatcatgg gtaaaccaga agatctggct gaggctgaat
    16261 tcatgctgaa aaaactaagc ggggaaacac atactgtata tacagctgtt gttttaaaaa
    16321 caaaggaacg agaagaacgg atactagcag aagcacatgt cactttttat cctttgacag
    16381 acgaagagat caaacgctac ttggagacgg gggattatgc ggataaggca ggggcatacg
    16441 gcatccaaaa tgctgcgagt gtattcgtca aagaaatttc tggagattat tacagtatcg
    16501 taggatttcc gattggtgct gtcaatcagg cactgaaaac attcatttaa acaaaaaagc
    16561 ggactatctg attttcgatt gaaaatccat gatagcccgt tttttttatt gaaaagatta
    16621 cttatctact ctgactaaga ttttacttca gctttaccga ctgcttcgcc cgggcgaaca
    16681 agtcctgatt ggtcaagaga aagtcctgca actttttcat tattggtcaa agcaacaata
    16741 atgtcagttt tcttgccagc ttgttctatt tctggcaaat ccatttcagc aatcagggtc
    16801 tctggtgtga caaggtatcc ttctttcacg aatacattga aaggaacacc ctttagttca
    16861 acagtatcta atcccatgtg aacaagtact tccagcccct cattagaaag aataccaatg
    16921 gcatgttttg tttcaaagac actcgtcact ttaccgttta ctggtgcata gactttgccg
    16981 tttgacggtt cgacagcata accgtcaccc atcatttttt gtgagaaaac tgggtcattt
    17041 acttcagtta tttccttgat ggtccctgca gcgactgcga ataatgtttc ttttgttgca
    17101 actgccgtac cagttgctga aacaggttcg aaagactgtg gcgttgctgt tgcgccattt
    17161 gctgtttgaa gttgtacatc agcagcattt tcaggaacag caggatcaat cttattcaaa
    17221 attccctgac gtctaaagat gatcgtcaag ccaaatggaa tgatgacagc aatgatcatt
    17281 gcgatgatga aaggtaccca tgtttctgct tggatagcta gtattcctgg caaaccgcct
    17341 actccgatcg cgttagctcg aacacccatc aagttagcaa acatgccagc taatccagag
    17401 ccgaccattg cagcgacgaa aggatagacg tatttcaaat tgattccgaa catagcaggt
    17461 tcagttacgc ctaagtaaca agaaatcatt gctggaatcg agatttgttc ttctttttta
    17521 ttcccacgat gtaagaagat gatggctaag actgcagagc cttgggcgat atttgataaa
    17581 gcaatcatcg gccataaatt cgttgatccg aaatctgcaa tcagctgcat atcgatggca
    17641 ttggtcatat ggtggagacc agtaatcact aaaggagcat acaggaatcc gaatacggca
    17701 ctaaacaacc agctgataga agacgtcaat ccagtattta cgatatttga gatccagctt
    17761 ccgactgtcc agccgatagg acctaaaata acgtgtgcag ctaaaacagt tggtaacaat
    17821 gaaaacaatg gaacaaaaat catcgagatc gactgaggga tatatttgcg gaagaagatt
    17881 tctagatacg ctaacataaa ccctgccagc atggctggaa taacttgcgc ttgataacca
    17941 atcatctgga cttgagcaaa accaaaatcc caaaatggaa tatctgctgc ggctgtggaa
    18001 gctacactat aagcatttaa taattgcgga gaaactaacg taattcctaa aacgattcct
    18061 aatatttgtg tagtacccat cttttttgca atactccaag tgatacctac tggaagaaaa
    18121 tggaaaattg cttcacccgg taaccacaaa aaggcattga caccattcca aaacttcgag
    18181 tgttcaacga ttgttccacc aagactttca aactggatac cttcaagtac atttctgaat
    18241 ccaaggatca atccaccgac aatgattgca ggaatcagtg gtgtaaagat ttctgctaaa
    18301 acggcaatag cacgttgaac gggatgaagg ttttgttttg cagctgcttt tccttgttct
    18361 ttggaaaccc cttcaactcc agatactgca acgaagtcgt tataaaaagt agaaacatcg
    18421 tttcctatga tgacttggaa ctgtcctgca ttcgtgaaca tcccttttac gctaggtata
    18481 tcttcgatcg ctttttcgtc cgcttttcct ggatcattca ggacaaaacg catacgagtc
    18541 gcacaatgac taactgcagc aatattttct tttccgccga tatcatgtaa cagcttctcg
    18601 gcatctgctt gatattttgc catatcaata aacccctttc tcttaacttg tctatgcaag
    18661 ttgtttcttc atttactata ctttttttcg gagagaattg caagcgtttt attaaaaagt
    18721 acgagagaaa atgatatcgt tttaaaaagc ttaaaataag cttttcttaa aaataggaac
    18781 attgaaatac aaaaagagct gtagtatagt gaagaaatga tggaagaacg agtgagggaa
    18841 aaaacatgaa taagttcaat gaaatttttt tagatttgga acagaaaatt ttagcgaaag
    18901 aatatcctcc gcattcgctt ttacccagtg agaaccaatt gatcaaaatt tatggtgttt
    18961 cacgagaaac aattagaaaa gcgctgaatc ttttgactac ggaaggttat attcaaaaaa
    19021 aacaaggaaa aggttcgatc gtactggatc ggaatcgctt cgactttcct atttctggat
    19081 tgactagcta taaagagcta caggagaccc aacgtattcc aagtgaaacg atcatccata
    19141 cgttagaaga aacagaagtg acaaaagcat tgaacgagat cactggctgg gagatcggtg
    19201 cgcctgtttg gcatttgata cgcgaaagaa aaatcaatgg cgaagtagtt atattagaca
    19261 ccgattatct attaaaggaa atcgttccta ttttaactcc agcacaagca caaggatcga
    19321 tctatgaata ttttgaaaat gagctttctt tgacgattgc ttacgcgcaa aaggagatca
    19381 cagtagaaga agtaacggaa atcatgaaaa cagcgatgga tcttcacgat gacacttatg
    19441 cagtagtagt cagaagcctc gttcatctgg aagatacccg ctgtttcgag tattctgagt
    19501 cggttcaccg attagataaa ttccgtttcg ttgagtttgc ccgacgccga aaagtgtaaa
    19561 tagttcaaaa gaaagcaaat tgttggcatc tgtccacttt ggcgctatga taggatcaca
    19621 aagggggcat ttttaatgga taaaccaata agaccagaaa aagaagaact gaaagaaaag
    19681 ttatcaccca tggcttatgc agtcacacaa gaaaatgcaa cagaacgacc atttagcggg
    19741 aaatatgatg atttttacga aaaggggatc tatgtagata tcgtcagcgg tgaaccgtta
    19801 ttcagctctg cagaaaaata tgatgcaggt tgtggctggc catcattcag caaaccaata
    19861 acgaaaagac aagtgcgcga aaaagccgat ttttctcatg gcatgcatcg aatagaagtt
    19921 cgaagcaaag aagcagattc tcatctcgga catgtgttta ccgatggacc agtagatcaa
    19981 ggtggtctac gttactgcat caattctgcc tcactgaaat tcattccata tgaaaagatg
    20041 gatgaattag gttatgggga attcaaatca cttgtagaat aatggaaata cacaaagagc
    20101 ggtacaatac ggggatttac tcgatcgtcc gctctttttt tattcaagcg attgctattt
    20161 gaaagaaacg ctccctagac tccttttttc acaaggtgaa atgtgctaca ataaagggaa
    20221 cgtatgtgtg caaaagaaag aggactagaa tatgtatgaa tatctgacag gtgtggttac
    20281 ctttatcaac ccctattaca tagtagtaga aaccaatggt atcggctacc agatcgcact
    20341 aggaaatcct taccgctaca gtagcaaact aaatcaaaaa ataaaaattt atgtccatca
    20401 ggtaatacgt gaagatgcgc atcttctgta tggatttgat tcgctagaag aaaagcaact
    20461 gtttttgcga ttagtaagtg tttcaggaat cggtccgaaa agtgcccttg caatcatggc
    20521 aagcgaagac cactccggtt tgattcaagc agtagaatcc agtgatgtca cttatttgac
    20581 gaaatttcca ggagtaggga aaaagacagc acaacaaatg atcttggatc taaaaggaaa
    20641 attcggtgag ctgagtatcg atacaccttt tagtctattt gatgaagcaa acacaaaaga
    20701 cgctacagct ctatctgaag caatggaagc tctctcggct cttggttaca gtgatcgaga
    20761 aatcaaacgt gtagaaaaac aattaaaaga agtagataat cagacaacgg atgagtatct
    20821 acgccaagca ctcaagctaa tgatgaaaaa ataaggagga gaccaaatga cagatgaata
    20881 cttgttatca ccagaatctg gcgaaaatga actgagtttg gaaaaatctc ttcgaccaca
    20941 gctgctttct caatatatcg gacagagaaa agtcaaacaa gaacttcaga tttacatcga
    21001 agctgccaga aatcgggaag aacctttaga tcatgttctg ttgtacgggc ctcctggatt
    21061 aggaaaaacg acgatggcca tggtcattgc taatgagatg accgtaaata ttcgtacgac
    21121 gagtggccct gctatcgaac gtccgggtga cttagtagca atcttgaatg aactggaagc
    21181 aggggatgtc ctgtttatcg atgagatcca tcgattacct agagtggtag aagagatgct
    21241 ttattcagct atggaagatt tctatgtaga tatcatggta ggacaagggc caaccgcaca
    21301 tccggttcat ttccctcttc ctccctttac tttgattggc gcgacgacac gggcaggtat
    21361 gctttctgca cctttacgag atcgatttgg catcatttct catatggaat attatgacga
    21421 acaggatctg caggagatcg ttttacgttc ttcggatatt tttcaaacag agatcattga
    21481 agaaggggca ttggaaattg ctcgccgatc acgaggaacg cctagaatcg ctaatcgctt
    21541 gctcaaacgg gttcgtgatt ttgcgcaagt ccaaggagac gggaaaatcg atcgtcctat
    21601 agcggatcag gcacttactt tgctacaggt cgatcaggct ggattggatt atgttgacca
    21661 gaaattgttg cgaacaatga tcgagttata tggcggcgga ccagtagggt taagtacgct
    21721 ttcagtaaac ataggagaag agcgtgagac ggtagaagat atgtatgaac cgtatctgat
    21781 ccaaaaagga tttttaaagc gtacacctag agggcgaatt gctactgctt atgcctatga
    21841 acattttggt tacgactatc atatatgatt tttgctttta gattggagga aaatgaatga
    21901 gtgatacaac acgtacgaaa caattgatca aaaacgtatt gattgatttg tgccaaacgc
    21961 aatcttttcg aaaaatcagc gtccaaaaaa tcgcaaacga agcaaaaatc aatcgacaaa
    22021 cattttatta tcattttaca gataaatacg atttgcttcg ttgggtctat tgtgaggatg
    22081 cattgcatta tttagatcca caatgtcttt cacttgataa ttgggaagag caagcattga
    22141 aaatgctgaa agcaattgct gagaagaaag aattttatgc aaatactgtg ctttctgacc
    22201 cagaaatttt acaaaaagag ttttctcaac tgatccaaaa atcatttatc aagatttttg
    22261 aacaaatgga tgaagaaaga caactttctg caagagacaa actattttat gctcgttttt
    22321 tttcttacgg ttgcagtggt gtattagtca attggatcac gaatgaatat gaagaaacac
    22381 cgatggaaat cgctatgcag cttttccgtt tagccaagga tacggaatta tattcttatc
    22441 gtctttatgc aaaagaagag ttggaagaac agtaatagaa aaattttttg ttggaaaagc
    22501 aataatcgct aaaaggagat ggggaaatga caaaaatttt atttgtttgt ttgggaaata
    22561 tttgccgttc accgatggca gaaggcttgc tgagaaaacg aatagcatta gaaggaaggg
    22621 aagcagaatt ttttgtggat tctgctgcta caagcacgta tgaagttgga aagacaccgc
    22681 accctggaac gaaaaaaata ttaaaccaag aaaaagtaga tatgacgaat atggttgctc
    22741 ggcaaatcac accccacgat tttgaaactt ttgattggat cattggcatg gatcaagaaa
    22801 atgtagaaga actgaaacga agagcaccac gctcagcgca ggggaaaatc catttgtttt
    22861 taagtagcat tcctggaaaa gaaaaagaaa atgttcccga cccatactat accaataact
    22921 ttgatgagac atatcacttg atcacagaag gcctgaatca ttggtggaat atttggattg
    22981 atgaaaataa aataacaaat aatttgtaaa gttaacgctt tctttttaag gcgatgttag
    23041 agcatttcct tgtttttttg taaaatgtta ggtaaaataa aattaattaa gtaacacttt
    23101 cttagctaaa ggaggagtgc attcgatgaa cgaagagaca gtatcgccaa tgaagaagct
    23161 tacgaagtta gttactcata cttcgtatca actttttgat tcttttgtaa atgacactga
    23221 agaacatgct aagaatgtac gattgcaagg aaagtttatt cttgagctgc aaaaagctgc
    23281 tactgaacat agtctagtta tcttacaagt aagagcaaat cgtttgagta gcaagtatga
    23341 aacgatctca ggctgggtgg cgacaaaaac ggtcgaaaaa gaccgagtga tgatccgcct
    23401 acaaaacgaa gagcagcaga tccggatggt tcctgtagaa caaattgaaa aaataacaat
    23461 cctttcacca gcaggggaac aggaacggtt atcaaaataa tttataccag atagaaaagc
    23521 acgtatgagc ttgtaccatc aatcattact aatcaaaaat aaccgaatgc tttaagctga
    23581 tatcagtaaa acggaacgtt ttaggatgag tatcatagca tgacagcatt cggttgatta
    23641 gttgaatcga ttggatggta caagtttttt tgataaaaaa aggtcctgct agccggggag
    23701 ctagcaggat aaggagttaa aaatgaaaaa gtgttgttag ggttgtttgt tggtatgctt
    23761 atataatagt cattagttgt gaatattttg tgacgaaagt tttcgaaagt tgttaagtt
//
LOCUS       DAFEEZ010000041        23659 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000041
VERSION     DAFEEZ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23659
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.042"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            257..532
                     /locus_tag="LP245_001760"
     CDS             257..532
                     /locus_tag="LP245_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519682.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            545..2623
                     /locus_tag="LP245_001761"
     CDS             545..2623
                     /locus_tag="LP245_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBL1519683.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            2783..4669
                     /locus_tag="LP245_001762"
     CDS             2783..4669
                     /locus_tag="LP245_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL1519684.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4681..5628
                     /locus_tag="LP245_001763"
     CDS             4681..5628
                     /locus_tag="LP245_001763"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBL1519685.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5648..6175
                     /locus_tag="LP245_001764"
     CDS             5648..6175
                     /locus_tag="LP245_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1519686.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6238..6891)
                     /locus_tag="LP245_001765"
     CDS             complement(6238..6891)
                     /locus_tag="LP245_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBL1519687.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7023..7865
                     /locus_tag="LP245_001766"
     CDS             7023..7865
                     /locus_tag="LP245_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL1519688.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8023..8919
                     /locus_tag="LP245_001767"
     CDS             8023..8919
                     /locus_tag="LP245_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL1519689.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8922..9635
                     /locus_tag="LP245_001768"
     CDS             8922..9635
                     /locus_tag="LP245_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBL1519690.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9655..10173
                     /gene="msrA"
                     /locus_tag="LP245_001769"
     CDS             9655..10173
                     /gene="msrA"
                     /locus_tag="LP245_001769"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL1519691.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10170..10397
                     /locus_tag="LP245_001770"
     CDS             10170..10397
                     /locus_tag="LP245_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBL1519692.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10549..11100
                     /gene="lepB"
                     /locus_tag="LP245_001771"
     CDS             10549..11100
                     /gene="lepB"
                     /locus_tag="LP245_001771"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL1519693.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11183..11683)
                     /locus_tag="LP245_001772"
     CDS             complement(11183..11683)
                     /locus_tag="LP245_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBL1519694.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(11962..12360)
                     /locus_tag="LP245_001773"
     CDS             complement(11962..12360)
                     /locus_tag="LP245_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1519695.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            12620..13480
                     /gene="ylqF"
                     /locus_tag="LP245_001774"
     CDS             12620..13480
                     /gene="ylqF"
                     /locus_tag="LP245_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBL1519696.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            13473..14240
                     /locus_tag="LP245_001775"
     CDS             13473..14240
                     /locus_tag="LP245_001775"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBL1519697.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            14296..15153
                     /gene="dprA"
                     /locus_tag="LP245_001776"
     CDS             14296..15153
                     /gene="dprA"
                     /locus_tag="LP245_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBL1519698.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            15275..17353
                     /gene="topA"
                     /locus_tag="LP245_001777"
     CDS             15275..17353
                     /gene="topA"
                     /locus_tag="LP245_001777"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBL1519699.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            17322..18698
                     /gene="trmFO"
                     /locus_tag="LP245_001778"
     CDS             17322..18698
                     /gene="trmFO"
                     /locus_tag="LP245_001778"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBL1519700.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            18896..19801
                     /gene="xerC"
                     /locus_tag="LP245_001779"
     CDS             18896..19801
                     /gene="xerC"
                     /locus_tag="LP245_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBL1519701.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            19838..20386
                     /gene="hslV"
                     /locus_tag="LP245_001780"
     CDS             19838..20386
                     /gene="hslV"
                     /locus_tag="LP245_001780"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBL1519702.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            20400..21800
                     /gene="hslU"
                     /locus_tag="LP245_001781"
     CDS             20400..21800
                     /gene="hslU"
                     /locus_tag="LP245_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBL1519703.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            21818..22609
                     /gene="codY"
                     /locus_tag="LP245_001782"
     CDS             21818..22609
                     /gene="codY"
                     /locus_tag="LP245_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBL1519704.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            22691..23566
                     /locus_tag="LP245_001783"
     CDS             22691..23566
                     /locus_tag="LP245_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBL1519705.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
BASE COUNT         8192 a         4079 c         4983 g         6405 t
ORIGIN      
        1 tttttgtcgc agccccattt ttttgttgtg ataaaagaac aagaaaggca ggaatgggaa
       61 agtaaacatc cttttgtcag aaacttttat ctttcttaag ttttacttga tatctgatac
      121 tatttggaat agaatgaggc gttgaaaaat ttatggaaat ttctaactag caataaacga
      181 tgaaacaatg aaatattttt catccaaaaa gaactttgct ataatgatgg aagtttgtgt
      241 ataggagatc tggaaaatga gagagagttt tgaacaacaa aaaaaactgt tgcatgatcg
      301 ctatggcgcc ctttcgatgg atgaccgccg tcaaatactt tgtaagttgc gtaaaagaaa
      361 tatattgatg tatcgtcagt tggaacgtct gaaacatgat ctgcttcgtt tggagtcaaa
      421 acgtgtacag tgtgaattag aggggaacca aacacaggtt gaagtagtcg aaaccaaaat
      481 tttaaagaaa aaagaacaat ttttaaaaat gcttacacaa aataaaaaat aaaggggatg
      541 gacgatggaa tttgctgagt tagttattgt atttgcagta acgatcacct tatcgaacat
      601 agctagccgc attttgccaa tgattccagc tccactgatc caaattttcc ttggagtggt
      661 attaggtctg acagagtggg gacaatcaat cgattttgaa cctgaattgt tcttagttat
      721 gattattgca ccattgttat ttagagaagg agaaaaagca gatatttctt cgattctcaa
      781 aaatttcggg acaattttgt tcttggcatt tggaggagtc attttgaccc ttgtcggggt
      841 aggtgcgacg ttatcattcc tgttgccaag tgtcccactt gctgcctgct ttgcttttgg
      901 agcagcgtta ggtccgacag atgcggtagc agtcagttct ctttctggac gagtgaatat
      961 ccctaaaaag gcgatgcata ttttggaagg agaaggtctt ttgaatgatg catctggtgt
     1021 tactgccttc cagtttgctc ttggtgcgct gatcaccgga tctttttcag cagtaaacgc
     1081 ggggatgagt ctagtagttt ctagtattgg gggagctttg atcggctttt tgcttgtctg
     1141 gttcaaacaa aaaataattc atttgatcga aaaagcatca gcacaagatg tcacagggta
     1201 tctgctgatc gaacttttgc ttccttttct agcctatgta ttggcagagg catttgatgt
     1261 atctggaatc attgctgcag tggcagcagg tattctccaa gcttctggtt ttaggaaaat
     1321 ctctgtgttt gatgcagaat tgtcgagctt gtcccacagt acatggacaa ctattgcttt
     1381 tacactgaat gcattagtat ttatattttt aggaatcgaa ttgacgcaag tgttctcgcc
     1441 agtatgggga gacggtttat atccaaacgg tcttttatta gcgattatcg tattaatctc
     1501 tgtcatgctt tttgtgatca gattcatttc tatcagtctt ttttatgtat tcaaagatgg
     1561 cagtaaaaag ttcaaaaaac agttgaacga gatcttgatc ttaacatttg gcggtgtaaa
     1621 gggaacagtc agtttggcta cgatttttat tttgccattt tcaatcaata atatgatgtt
     1681 ttaccagcgg tctttgcttt tgtttctgac ggcgggtgtc atcttagtga ctttggtcat
     1741 agggatcatt gtcttgccta tgctgacgga aacagaggaa gcgaaaagca cggatttgaa
     1801 tgctttgatg attttagaag aggtcgttga agttttgcga aaagaaataa aggaaattga
     1861 tcgtaataca aaagaatttt tagccactga agcagtgata gaaaattatc aagaacggat
     1921 acgtgatctg tacttggaag atttaaccga tgatgaaaag caagaagtac aagaaataca
     1981 agcactgatt ttgtcgatcg aacgggatgg attggatgaa agttatcgtt cgggcaagct
     2041 ttcttctaat ggttatcgtt tttactcccg ttttctttct cgattcgaac attctatcac
     2101 aagccagatt ttgtctttta tcggcttttg gttcattgtt gtccgtaggt taatgcgaat
     2161 cgttctccat ccgaaaatgt tttggcaaag aagatatgct gatcgtcaga catttattag
     2221 tgatgaagat atccaagaaa tcagagagac atatcaaaaa aatactcagt tgattattga
     2281 aagtttagat aacttgactg atatttatga tgaaacgatg gttcaatttt ttatccagca
     2341 acgcaaactt gaaggaataa aaatgaactc ggggaatttg atttcttcgt ggatgatcca
     2401 gcaagatagt ctgtttacga aaaaaatgct aagaggttat tatcttgaaa gaaaaatcat
     2461 tgatgaatac gaagttgctg aaaaaatcac gacgttttct gcgaacagct atcgcaggaa
     2521 tatcaatttg ttagaatctt atacgatgaa caaaccatct gataactttt ctttccgatt
     2581 tgcgtttcga gcaaagtcaa aaaaaacgag tccaataaaa taaaaaggta aaaattttca
     2641 agttttataa aaaacaaaac atatcagaac aggatcgaat cggtcctgtt ctttttttga
     2701 gaacacaaaa agaacaaata ccaaaaaaat tttcctgaag ttcactattt ttatgataca
     2761 atatccaaga taaggaggga acatgttgaa agaattaaaa gtaactgacc tcaaaaaaac
     2821 ttatggtgaa aaagatttgt ttgaccagat ttcttttttg gtccacgaaa aagaccgtat
     2881 cgggttgatt gggacgaacg ggacgggtaa aacaagtctc ttaaatatta ttgccggtat
     2941 cgatagcagc gacggtgatc ggcaaacagt gttttatcca actgattacc gtattggtta
     3001 tctttctcaa gcagctgaat tttccgatga attaactgtt ctccaagcag tctttcaagg
     3061 aaacagcccc ttgatccaaa ctgttcgagc atatgaggaa gcattgatcg aactagggga
     3121 aaacggagaa gaccctgatg tgcaaaaacg ttatgctaaa gcagaagaac aaatgaataa
     3181 agaagatgct tggactacag ataccaacgc aaagattatt ttgcaaaaat taggaatcag
     3241 tgaattagat aaaaaaatca gtactttatc aggtggtcag aaaaaacgag ttagtctggc
     3301 gcaagtgttg attgatgaac ccgatttact attactagac gaaccaacaa accatttaga
     3361 ttatgaagcg atcgagtggt tggaaaacta tttgaaacaa taccgtggcg cactattgat
     3421 ggttacccac gatcgttatt ttctagatag agtagcaaac cgaatcttcg aactttcatt
     3481 tggaaaatta tacgagtata aaggaaatta tgaagcttac gtcttagaaa aagcagaacg
     3541 tgatcgtgta gaagtagaac aagaagaaaa gcgcaagcgg ctttataaac aggaattagc
     3601 ttggatgagg gctggcgtac aggcacgtgg caccaagcag caagcacgga tcaaccgttt
     3661 cgaagatcta aaggagaact tgtaccaagt aaaccaagaa gatgatttag agctgaacct
     3721 agcgacacaa cgtttaggga aaaaagtact ggaaatcaaa gatggcagtt accgtataaa
     3781 tgaccaaaca ctgctagaac atttagattt attgattcaa tctcgggaaa gactaggtat
     3841 tactggtaaa aatggtgcgg gaaaatcgac attgcttaat attctagctg gcagaattcc
     3901 cctggatagc ggtacaatgt ctatcggtga aacggttcat cttgcgtatt atacacaaga
     3961 aaatgaagaa atggcaccag ataaacggat gattgcttac ttacaagaag ctgctgaaga
     4021 agcaaaaaca gcagatggca gtcaaatcgg agtagcagaa ttacttgaac gatttttatt
     4081 tccaagattt atgcatggga cactgatagg caaactttca ggcggagaaa aacgccggtt
     4141 atttttgttg aaactgctga ttcagcaacc taatgtttta ttattggatg aaccgaccaa
     4201 tgatttggac atagcaacat tgacgatttt ggaagattat tttagaagtt ttccaggtgc
     4261 tgtgatcact gtttcccatg accgttattt cttggacaag gtagcagata agttattagt
     4321 attccaagga aacggaaaac aagaacttta ttacggaaac atgtccagtt atttactgaa
     4381 gcaaaaagag acccagcagc ctgctgaaaa agcgaaacca aaaatacaga gcaaggaacc
     4441 tgctgaaaag aagaaattat cttacatgga acaaaaagaa tgggaaacga ttgaagatga
     4501 gattgcagaa cttgaagaaa aaatctcatt gctccaagaa gagatgaatc atcaaggaga
     4561 taatttcact cgattacaag aattgcaaaa cgacgtatct gaaacagaag cacaacttga
     4621 agaaaaaatg gcacggtggg aatacttgag tgaatgggta gaagattagg aggaaaaagg
     4681 atggaacaag cgtatcttga cttaggaaga aaattgttgg aagaagggca tcgtaaagaa
     4741 gacagaacag gcacaggcac attaagctta ttcggatacc aaatgcggtt tgatctgcaa
     4801 aaagggtttc ctttgttaac aacgaaacga gtaccttttg gattgatcaa aagcgaattg
     4861 ctttggtttt taaaaggaga tacgaatatc cgctatctat tacaaaataa aaaccatatt
     4921 tgggatgaat gggcatttga acgctacatc aaaagtccag actataatgg accagatatg
     4981 actgattttg gccatagatg tttgacagat cctgaattca atgaagaata taaaaagcag
     5041 agcaagcttt tttgcgagaa gatcctaacc gatgattcct ttgctgaaac atacggcgat
     5101 cttggacaca tctacggcta tcaatggcgt cactgggaaa caaaagacgg tggctttatc
     5161 gatcaaatca aacaagtgat cgaagcaatc aaaaagactc ctgattctag aagattgatc
     5221 gtttctgcat ggaatccgga agatgttcct agcatggctt tgcctccttg tcatacgatg
     5281 tttcaatttt atgttcaaga gggacggcta agctgccaat tgtatcaacg cagtggggat
     5341 gtgtttctag gcgttccgtt caacattgca agttatgcgt tgctgactca cctaattgca
     5401 catgaaacag gtttagcggt tggcgaattt gttcacacat taggagatgc tcatctttat
     5461 atcaatcata tcgaacaaat gaaagaacaa ttgagccgag aaatacgcgc atttccgact
     5521 ttagttttga atcaggaaaa gcagtcagta tttgattttg agatggaaga tatccaatta
     5581 gaaggatatg acccacatcc ggcgatcaaa gctcctatcg ctgtttagaa tcagaaagga
     5641 tgagaaaatg ttagctgcaa tttgggcaca ggatgaaaac ggattgattg gaaaagaaga
     5701 ccgtcttcct tggcgtttgc caaatgatct gaaattcttc aaacaaatga cagaagcaaa
     5761 tacactagtg atgggacgaa aaacattcga agggatgggt agccgtccgt tgccgaatcg
     5821 tcagacgatt gttttgacga gagattcttc ctataaagca gaaggcgtgc atgtcatgca
     5881 tagtgtggaa gacgtgcttg ctctggaaaa agaaacagac ggtatctttt tcatcgctgg
     5941 agggtcagct gtttatcaag aatttctgcc attttgtacg atattatacc gtacagtcat
     6001 ccatcatgta ttcgatggag atgcttattt tccacctgtt gactggtctg attggtcact
     6061 gatcaatact agtcaaggag aaatggatga aaaaaatcgt tatccgcatc aatttgaaac
     6121 gtatcagcgt aatgagaatc ctgtaaaaag cgggacaggc gaattgacga tataaaaaag
     6181 ctatggatag actagctgtt atttagagct gtcccatcca tagctttatt ttttttatta
     6241 agtaaagaat aaaacagaga agtacataaa acctgcacct aacataacaa acaaatgcca
     6301 aacaacatgc atatagcgga tagaattcaa gctataaaag aatgcgccta tcgtgtaaga
     6361 aagcccgcct gctaccatca aaataacacc agtcattcca agagagtgat aaagaggaac
     6421 agcagccacg acacagagcc accccataaa aatatagatg atcgtagata cttttgatac
     6481 tctctcccgt ttatgcaacg tcaacgcttt atatataatg ccaagaatcg caaacaacca
     6541 gattaataca aataaagtcc aacctagcca tcctcggata ctcagcaaac aaaaaggagt
     6601 ataacttcct gcaatcaaaa gaaaaatcga actatgatcg aatacttgga acaccttttt
     6661 tgcttttgta aaaatcaatg aatgaaacaa agtagacgtt aaaaataaaa gaatcatcat
     6721 cgatccatag atagcataag agacaatatg gagggaggaa tgcaagtggg caccttttac
     6781 taaaagaacc actagtcccg cgatactcaa tccagtccca attccatggg tgactgcatt
     6841 aaacacttca tttaatattt catacgttcg attaaatttc gttttttcca tgaaaacggc
     6901 tcctttacta ggtgtaatta atgaaaaatc attatttgtc tgttatacta aaaatagaaa
     6961 ttgtcttaca tgtagtttaa catgaataag gcatcttgtt aaagaaagag agagagaaaa
     7021 taatgacaaa tgtaaaaatc gtaacagatt cttcatgtac gatggaaaaa aatgtacgcg
     7081 atgctttagg cattcgtgtc atgccgctat ccatcatgat cgacggaaca gtatatcccg
     7141 atgatgacca actagacggc gaaagattta tggaaatgat ggcgaaagca aaaaatctgc
     7201 ccaaaacaag ccaaccacca attggagaat tcatctcgat gtatgatgag ctaggagaag
     7261 acggcagtga agtgatttcg atccatatga caaaaggctt gagtggaaca gtagaagcag
     7321 caagacaagc cagtaatcta acaaaaacga aagtaacggt tatcgacagt gataccactg
     7381 accaaggatt atcttttcag gtaattcgag cagctgaatt agcaaaagaa ggtaaaacag
     7441 tagagaaaat ccttgaagaa gtcaaaaaag tacaagacaa tacaaaatta tacatcggaa
     7501 tatccacact agataacttg gtaaaaggtg gaagaatcag ccgaacaact ggtttgctgt
     7561 ctagtgtttt gaacatacgc gtggtgatga atttcgccca ttctgaatta atccctgtaa
     7621 ctaaggggcg aggaaagaaa acgttcgata aatggtttaa taatttgaaa aatgaactga
     7681 aagaattgcc aaatgtgcga caaatcggta tttcacatgc ggatgcaaaa gaattggcgc
     7741 aagaattcaa agagggtttg caagaattat tcccggacat gcatatccct gtactgcata
     7801 cgaatccggt tatcgctacg catactggta aagacgcgtt tgcaatcatg tattatgtag
     7861 attagtcgaa aagaggataa gccctcagcc tgaaaggctt gcagcttatt ctctttttct
     7921 ttataaaatt aggaaaataa ttgttttctt ttttcataaa gactaccttt ttgataaaat
     7981 ttttgataac attagaacca atcgaataca agaggtgaaa aaatgaaatt aacgaaacga
     8041 catttgatcc tcgttttgtt cccattatta attgcgatca tcatctatgc aggtttagct
     8101 gcttctatac cgaaagctgg cccactaatg aaaccagtaa ctactgtgag agaagatcca
     8161 aataaaaaag aaaaacttca ctacatagct atcggagatt cgctgactga aggagtagga
     8221 gatcaaacca agcaaggagg attcgttccc cttgtcgcaa atgatctaaa agaccgttat
     8281 aatttgaccg cggttgaaac agaaaactat ggtgtaaatg gtgaacgaag tgaccagatc
     8341 ttaaagcgag taaaaacaaa agaagaaatt cgaaacaata tcaaaacagc tgattttatc
     8401 acactgactg ttggcggtaa tgatttgatg aaagttatcc aaaataattt attcgggtta
     8461 acggtcaatt cctttaaaaa gccactgaaa aactatcagg aaaatgtcac agaactattg
     8521 gaagaatttc gatccctcaa taaaaccgca cctatttaca ttttaggcat ctacaatcca
     8581 ttttatttga actttcctga gatcactgac atgcagacaa ttgttaacaa ttggaacaaa
     8641 ggaacagaaa cggtgacaaa aaaaatgccg aactgctact ttatcccaat caatgatttg
     8701 ctttatcaag gattgaatca ggaagtaggt gtcacagaag aaggaacaga tcaaacaact
     8761 agcacgacag aaaatctaaa tggcatcaaa aataatgtgc tctatgaaga agatcatttc
     8821 catccaaata atttaggtta tcaattgatg gcaaatgcag tgagagatca gctgatcgag
     8881 acacaaaacc aatggttaga gaaggaggat gatcaataaa catgaaaaca agatctgacg
     8941 tatcttcaaa caaaacaaag aaaacaaatt actggaaatt cgccttcctt atccttcttg
     9001 gggtagtact tggttcgacc gtatttttag gcagccgtat ttttgctaat cgggaaccag
     9061 aactcccaga aataccagct cttacggaaa gacaaggaga tcctgtctta acgatcaatt
     9121 caaataaaga aaaagtcaat caaatcatca gctttttcct tagtgagtat caaaaagata
     9181 gtgatattga atataaattt tatttggaaa atgaagcact actcaatggt actttcgaag
     9241 tactaggttt tcctatcgat ttctatttat attttgatcc gtatgtgatg gaaaacggaa
     9301 atgtccaact aaaagctaga agtctttcta tcggaacatt gagtttgcca atcaaagatg
     9361 tgatgaatat gatcaagaga aactataaat taccagattg gatcgaagtc aatacagatg
     9421 atctgactat catgcttagg ttggatcaat tccgaatgca aaacgggatg tatattaaag
     9481 cagataaaat cgacttagta aatgatgaca ttcggtttag tctatatttg ccaaaagata
     9541 cctctgatgc ttcaaacaac tcaaatacca acaaaactag caccagcagt actgaaagca
     9601 agacaaaaga aaataaaaaa tcatcggatg agtagtatta gagggggaat cataatggaa
     9661 cgagcaatat ttgcaggagg ctgcttctgg tgtatgatcc agcctttcga cacgcttcct
     9721 ggtatccata cagtgatgtc aggatatact ggagggcatg taccagatcc gacttatgaa
     9781 caagtaaaaa gccaaacgac tggacataca gaagcagtgg agattatcta tgatccaaca
     9841 ttgatttcat atgaacaatt agtagaactt tactggcagc aaactgatcc aactgacgct
     9901 ttcggacaat tcgaggatcg cggtgacaat tatcgcccgg tgatctttta tttgacagaa
     9961 gaacagcgga tcattgctga aaaaagtaag aaacagttag ctgaaagtgg acgtttcgaa
    10021 cagccaatcg ttacaaaaat cgaaccagcc caaccatttt atctagcaga agaagaccat
    10081 caagagtatt ataaaaagca tcctgaaaat tttaaaagaa accatgcacg ccgggctgcc
    10141 tttatcgaag aaaattggag gaacgaaggg tgaatcgaag cttttttcat tatttaatga
    10201 cactgcgagg cggtggcaca catgatgctt tatctgtttt cgctacagaa gccggtaaag
    10261 acatccaatt tcctaagcac agctctagct acgaagaaat ttctaattat ctggaactga
    10321 atgtcgacta tttgccgtcc atggatatct ttgacgaagc atgggaaaaa tatttagaaa
    10381 ataatcatga catataagag atagttttgt actttatgat caaaaaagtt ttttgtccaa
    10441 tagcctaatt gaaagaatta tttttatttc agctatctag tcgcattttt ttgatatttt
    10501 tcttataata aagaaagaat gaaaaaaaga gggatggatt gatagagatt gacaaaaaaa
    10561 caacgctata ttaatcgctt ctggcttgta ttcaaatact tacttgtttc tgtattcctt
    10621 gcgttcatgt tgcggggatt tttattcatc ccggtaccag tggaaggcaa ttcaatggaa
    10681 aacgtgttga agcaaggtga tatggttgtg atggaaaaat tttcggagat cagacgattt
    10741 gatattgttg tttttcaatt agcagatggc acgatttata tcaaacgagt aatcggtctt
    10801 ccaggagaaa atgtcagcta ccaaaatgat caattgaaga tcaatgggaa agtagttaag
    10861 gaaccttatc taactaaaaa cctgaaatca gatcatgcaa atgcatccta tacgacggac
    10921 tttacactac aagagctaac gggacaatcc aagcttccgg aagataatta ttttgtactt
    10981 ggagataatc gaagagtttc aaaagatagt cgttcgtttg gcacgatcaa taaaactgat
    11041 attctaggta aagcaagatt tgtctattat ccacttgatg aaataaaatg gatccagtga
    11101 gaaacaataa agcgtgcagt ctgttgagac tgcacgcttt attgtttaat ccaaaatcag
    11161 tttactacct tagtacgtaa aatcaaacag ctcgtttaaa cacttttcta gcctctaaag
    11221 ttttgataaa tgaataaaca accattattt gaatagggat ttggatcata ttcctgatga
    11281 atctacctag aaaaattact ttgaaatctg caccaaacaa aacagacatc agccaagaat
    11341 tgataaaaag gctgactggg atcataatca ataattgggc agcgatgacg gaaggcaggt
    11401 ttatcttttt atgatataaa aataagccat taataaatcc accaaggaaa gccgtgataa
    11461 gaaaagcagc ttgaaacgtt cctgaaccaa atatcgtgaa atttaaagtg ttcgacaaca
    11521 tttcaagcaa accagcccag atcggtccat atagataacc cataagcgcc atacttaaaa
    11581 atccgaatgt gatttgaaaa taagcaggac caatcgctat cttgtataag atgacatcaa
    11641 gggctaataa aagagcagag gtcgacaaca atcttgcatt catttcgggc aatctaaaaa
    11701 cgtcttttgc aatcaaagtg ttcaaaatat tctctccttt gtcagttaat aataaaagga
    11761 taccataaaa tcaccaatgt gtcatgacac attggtgatt tacatacact ggcatctaac
    11821 aattaaaaaa agggtgagaa gactgctttt ataaactgta aaaaagagat tgtacgaata
    11881 aaaaaaatag aggcggagaa tacttatcgt atcatccgcc tttgtttttt tgttataaaa
    11941 aacgtcagat tagttatctg cttacatctt catccatacg ggttctaatg tatttccgtc
    12001 tagatcttgg acttctaatg aaaacatttc ttcttcaggc attcccatat ctacttcgtg
    12061 gaaagtacca ccattttctt ttgcaatttg agcaaatttt tttacttcat ccgcattttc
    12121 aacactaaac gaaatcaaag caccacttgt ttttttatta tcagctattt ctttatcttt
    12181 tataaatttt ttataaaaat catgagagag aagcattatc caaaaagtgt catcccatac
    12241 cattgaacca gcttcttcag tagaaaattc ttcatttttt ttaaaaccca gcttttcata
    12301 aaaagcaacg gaacgattga catcagcaac aggaaaatta acaaaaacca tactattcat
    12361 ttgtttcgtc tcctttctgt tttgttcgtc tatcatctct tatttaggaa acgctgtcaa
    12421 aaatttagat tcatatatag aaaccaaaat aaaaatttgc atcatcaaaa aagtgaagat
    12481 gtgatagaat gaggactggt tcactttcac ttaactaata gatggaattt ctttataata
    12541 aaaaagtgaa tttatattga aaaagaaaaa aacaagtaaa gccggggaat attccggtat
    12601 gaaaggaatg gagagaacaa tgaccatcca atggtttccg ggacatatgg caaaagcccg
    12661 acgagaagtt tctgaaaaaa tgaaatatgt ggacatcgta tttgaattgg tagacgcacg
    12721 attaccttta tcttctcgta atccaatgct agatcagatc attcagcaaa aacctcgcct
    12781 tgttttattg aataaagcgg atctggcaga tccacaacag acaaagctgt ggcaagaata
    12841 ttttcgtaaa caaggccatc ttgcattagc tatcacggca caagaaagta aaggaattaa
    12901 aggtctagta cctgcggcta aagaagcatt gaaagaaaaa cgggcaagag atgctgctcg
    12961 ggggatcaag cctcgcgcta ttcgggcaat ggtcttaggt attccaaatg ttgggaaatc
    13021 tacgttgatg aatcgactag taggcaagaa aattgcacag acaggaaata agcctggcgt
    13081 aacaaaaggt cagcagtggc ttcgtttagg taatgagttg gaattgttag acacaccagg
    13141 gattttatgg cccaaatttg aagatgaaga aatcggcaaa aaactagcgc tgacaggcgc
    13201 gatcaaagac cagcttgtcc atttagatga tttagcgatt tacggattag acttttttgc
    13261 ccgatattat tcaggaagaa tcagcgatcg ttatggttta tcaatcgagc aagaagaaaa
    13321 attggcaccg gaattactga tggatattac agcaaaacgt gggtataaag aagactatga
    13381 tcgtggcagc gaattagtcg tgcatgatat tcgtcaagga aaacttggac gatacacact
    13441 ggatcgttgc gaagaaatgg agcaaaaaag tgatgactga atccatccaa agtatcaaag
    13501 aacgattgaa aagcatacag agaatagatg atcctacact agaatcatta agaaatgatc
    13561 cacgcaaagg cgtgcagcaa gcactggctt cttttgaacg acgattgaaa aaggaagcat
    13621 taattaagga aaaatatgaa gaaatgtttt gctttgaaaa gcaagggtac gcacaaggtc
    13681 accaatggat tgccggcatt gatgaagtag gaagaggacc attagctgga cctgtcgtgg
    13741 cagctgcagt tatcttgccg aaaaatgaga tcatattagg gctgaatgac tccaaacaat
    13801 tatcagagaa aaagcgagaa cttctttatc aacaagttca agaaaaagcc ctggcaatcg
    13861 ggatcgggat cgttgatcag cagacaatcg atgatgtgaa tatttatgaa gcaagtaaat
    13921 tagcgatgat ccaagcagta gaaaaattgt ccattgtacc aagctatttg ttgatcgatg
    13981 cgatgacctt ggatttgcct attcagcagg aaaaaataat caaaggggat gcacgatctg
    14041 tgtcgattgc tgctgcaagt atcattgcta aagtatatcg agaccaattg atgaaagaat
    14101 atgacgtgct ttatcctgga tatggtttct cgcataatgc aggttatgga acaaaggaac
    14161 acttagaagg acttgaacga caaggaatta cgccaatcca tcgtaaaagt tttgcacctg
    14221 taaaaaaata tttacaataa aaaacagccg cttttacgta tcttattaga aagagagacg
    14281 aaaggcggtt ttatgatgta tcaaatagaa gaaaatttat tgaaacttgc ttatacaaaa
    14341 ggaatcagta gtcaaggaaa atgggcactt gctaactgga tgatgcagta tccttataaa
    14401 gaaatcggat ttgaagacat cattaagata ggtaaaataa ccaaacaccg ggagctgttt
    14461 cgcaaaagtt ggcaggaaat tcacgctaac tggggcaaaa tccaatcgaa acagtcgttt
    14521 atcacttgct ttgatcccaa atatccccct cagctgcttc acttgaccta tccgccaatt
    14581 gtactgtttt ataatggtga tctatcttta ctttcttgta acatgttaag cgttgttggt
    14641 ggaagacaca cttctgcttt agccaaaaaa acagtttatt atttactaaa accagtgata
    14701 gaagctggat atgtgatcgt cagtggctgc gcgaaaggga tagatacata cggtcaccaa
    14761 gcagcaatct ctcatggtgg acggacaatc gcagtcattg gaacagggat agagcaagtc
    14821 tatcctgctg aaaatcgtga cttgcaagag gtgattgcaa atgatcatct tcttttgagt
    14881 gaatatcctc ctcaatccgg cccgaaaaag cattgttttc caatgagaaa tcggattatc
    14941 gcagctttgt ctaaaggaac atgtgtcttt gaagccaaga aaaaaagcgg ctctctgata
    15001 acagcacagc aagcattgga tcttggaaga acagtttttt ctgttccagg aaatatttta
    15061 acagaacatt ctaccggatg tcatcatttg atccaagacg gtgcagtttg cacggtttcg
    15121 ggtgaagata tcttggcaga atttaaagaa taacaccata cttttcattt gcttttcttg
    15181 acaaacgttt tctgaatgga tatgattagc tacgatttgt atgaatcctc ttttaatagt
    15241 aggaacacga caatggaaag gagtccattc agtaatggcg tataaatatt tagtgattgt
    15301 agaatcacct gcaaaagcca agacaattga gaaatatctt ggacgaaact ataaagtaat
    15361 ggccagtgtt ggccatataa gagatttacc gaaaagtaaa atgggtatcg attttgaaaa
    15421 caattatgaa ccccattata tttctatacg cggaaaaggc gatgtcatca aaagcctgaa
    15481 agccgcagca aaaaaagctc aaaaagttta cttggcaagt gacccggata gagaaggaga
    15541 agcgattgct tggcatttag cgtacctact tgggttggat ctgaaagaaa aaaatcgggt
    15601 ggtcttcaat gaaatcacaa aagacgcagt caaagcagct tttaaggaac caagaacgat
    15661 cgatgtagat ttagtagatg cacagcaagc tcgtcgtacc ttagacagaa tcgttggtta
    15721 ttcgatcagt cctattctct ggcgtaaggt caagaaaggg ttaagtgcag gacgtgtcca
    15781 atctgtcgct ttaaaaatta ttattgaccg tgaaaaagag atccgagaat ttgttccaga
    15841 agaatattgg agcatcgacg gtaattttaa aaaagctcgc aagaaattca aagcaaattt
    15901 ctggggaatc gacggtaaga aaaagaaatt accagatgca caaagtgtaa aagaagtcac
    15961 tgctagaatt gatggaacag acttcgaagt taaaaaagta gaaaagaaag agcgcaaaag
    16021 aaaccctgcg aatcctttca ctacaagtag cctgcaacaa gaagctgccc gtaagttaaa
    16081 ctttcgaaca agaaaaacca tgatggtagc acagcaatta tatgaaggaa tcactttggg
    16141 taaacaagga acagtcggct tgattacata catgcgtact gattctaccc ggattgccga
    16201 tacagcaaaa gcagaggccg cagcatttat tgaagatacg tatggaaaag aattttctag
    16261 acatgatcac cgaaagatca aaaatgctca aggcgcacaa gatgcccatg aagctgtgcg
    16321 tccaacgagt gtgcttcgta caccagatga actcaaacaa tatttagata aagatcaatt
    16381 gaaactttat acattgatct ggtcacgttt tgtggctagt cagatgacac cagctatttt
    16441 agatacaatg aaagtgacat tagaacaaaa tggtgtcatc ttcattgcga acggttcaaa
    16501 aatcaaattc aaaggattca tgcaagtgta tgtggaaggt agagatgacg gcaaagaaga
    16561 gaaagaaaat attcttccag aacttgaaga aggcgatgta gtccaatctg ttgatattga
    16621 accaaaacaa cattttactc aaccaccagc acgttttagt gaggctacgt tgattcgtgc
    16681 actagaagaa aacggggtag ggcgaccttc cacttatgca ccaacacttg atacgatcca
    16741 aagacgctac tatgtaaaat tgacacaaaa aagatttgag ccgactgaac taggagaaat
    16801 tgtcaattca ttaatctgtg aattcttccc tcaaatcgtc gatatccatt tcacagcaga
    16861 aatggaagga gatttggata aaattgaaga aggcacggaa gcgtgggtca aagtggttga
    16921 tcgtttctat aaaccgtttg aaaaagaact gacgaatgcg gaagaaaaaa tcgaaaaaat
    16981 tcaaatcaaa gatgaaccag caggattcga ttgtgatgtc tgtggacatc cgatggtgat
    17041 aaaattaggg aaatatggga agttttatgc ttgcagtaat tttcctgatt gtcggaatac
    17101 gaaaccaatc gtaaaagaaa tcggtgtgac ttgcccagta tgtcatgaag gacaagtcat
    17161 tgaacgaaaa tctaagaaaa acagactatt ctatggttgt tcccgtttcc cagaatgtga
    17221 attcacttct tgggataaac cagtgggcag aaattgtcca aaatgtgacg gatatctggt
    17281 cgagaagaaa gtcaaaggcg gtaaacaagt agtctgtgta aatggagatt acgaagaaga
    17341 catccaaaaa taatagaaaa gaggttcttt cattgaaaat ggtaaatgtt gttggagcag
    17401 ggcttgccgg aagtgaagct gcttggcaga tcgcacaagc aggagtccct gtccgtttat
    17461 atgaaatgcg tccagtcaaa tcgactgagg cgcatcacac aagtaatttt gctgaactag
    17521 tatgttccaa ttcattaaga ggaaacagtt tggctaatgc agtagggtta ttgaaagaag
    17581 aaatgcgccg attgaattcg gtagtaatca cttcggcaga tgaaacagca gtgccagctg
    17641 gtggtgcctt agctgttgac cgcgattctt tttctgaaac aattacccga aaagtcaaag
    17701 agcatccatt agtaacagtg ataaacgaag aaattactga aataccggaa ggaatcaccg
    17761 tagtagcaac aggacctttg acttctcatc cattagcaga aagcatcaaa gcattcaatg
    17821 gttcagatgg tttttatttc tatgatgcag ctgcaccaat cgtagacaaa gctacgatcg
    17881 atatggataa agtatatttg aagtcccgct atgacaaagg agaagcagct tacttgaact
    17941 gtccgatgac agaagaggaa ttcaaagctt tccatgaggc actaatcaat gccgaagtgg
    18001 cagaacttaa atcttttgag aaagaaaaat attttgaagg atgtatgcca attgaagtaa
    18061 tggcacagcg aggattcaaa acgatgcttt tcggacctat gaaaccagtt ggattggaag
    18121 atcctaaaac tggcaaacgt ccttatgctg ttatccagct gcgtcaagac aatgctgcag
    18181 cttctttata caacatcgtg ggctttcaga ctcacttgaa atggggcgag caaaaacgtg
    18241 ttttccggat gattcctggg ttagaaaatg ctgaattcgt tcgctatggt gtgatgcacc
    18301 gaaacagctt tatgaattcg ccagaattgc tgaaaccgac ttaccaatca acgaaacgcg
    18361 aagatctgtt ctttgcaggt cagatgactg gtgtagaagg ctatgttgaa agtgcagcga
    18421 gcggactact tgctggaatc aacgccgcac gcttagcaaa agaaatggaa ccagtcgagt
    18481 ttccacaaga aacagctatt ggaagtatgg cttactacat tactcatgcg gaaggaaaac
    18541 atttccaacc gatgaatgcc aactatggtc tgtttcctga actgccagag cgcattcgag
    18601 acaaaaaagc aagatatgaa gcaattgcac aacgagcttt aaaagctaat gaggcaataa
    18661 aaacagaatt agaaaaaact gcaatcccaa atgagtaagg aaactccatg aagagggtga
    18721 gacggatagt ctcgctcttt ttcttgcgtt tttcttaaga atttctcaaa caaaatgtga
    18781 ggaattgcgc caattgtgaa caaacttaga aatattggtt aaattctgac aatttatttg
    18841 tctttttata aacgctgtgc taaattattc tctgggacaa aaggaaggtg agaaaatgac
    18901 agaagccacg tgggaacaaa aatttttgcg ttatttgatt gtcgaaagag gatattcaga
    18961 aaaaacgaaa gaagcatatg aagaagacat tctccatttc aaacattttt tggaggaatc
    19021 tggagacgct gatctgctga aggcggaata ttttacggtt cgtgtctatt tgagtgcatt
    19081 agctgatcat cgtcctagct atagcagaaa ttctatcagt cgcaagatag ccagcctacg
    19141 ttcgttttat cagtatcttc tcaaagaaga agtgataaaa gaaaatccat tttcttacgt
    19201 tcatctcaaa aagaaaaatt tgagactgcc acgttttttt tatgaaaatg aaatgcaagc
    19261 actttttgac agcgtagcag gagatagtcc tttggatttg aggaaccgcg ctttactgga
    19321 agtcctttac gggtcaggca tccgtttaag tgagtgtagc agtttgtcgg tatcagacat
    19381 tgattttgat tcagaggtca tgttgatcca tggtaaaggg aacaaagaga gatatgctcc
    19441 tctaggttct tttgctcaag atgctctgca agaatatttc agggaaggcc gccaggtatt
    19501 gatgacaaaa tatcacgaag agcatgatat cgtttttgtg aatcatcatg gaaaaccaat
    19561 cacgcctact ggaattgaat atgtcttgaa tcaaatgatc aaaaaaagca gtttggatag
    19621 tgatatccat cctcacatgc tgcgccatac atttgctact catttattaa ataatggggc
    19681 agatttgcgg acagtccaag aattgctagg acatgccaat ttatcgacta cccagatcta
    19741 tgcccatgta acaaaagaaa gtttacaaaa aaactatcgt tctttccatc caagagcgta
    19801 aaaataagga aaagaacaaa tttaggagga aacaaacatg gtcgaatcac catttcattc
    19861 aaccactatc tgtgccgtcg aaaaagacgg gaaatttgct atggctggag atggccaagt
    19921 aacaatgggt gaatctgttg tcatgaaagg cactgcaaag aaagtacgac gtatctacaa
    19981 tggagaagtt gttgtaggtt tcgccggaag tgttgcagat gcgtttactt tagaagaaaa
    20041 atttgaaggc aaactaaacg aatataacgg gaatctacaa cgcgcagctg tcgaattagc
    20101 tcaagaatgg cggacacagc aatctatgca aaaacttgaa gcgatgctga tcgtaatgaa
    20161 tgataaagaa atgcttcttg tttcaggtac aggagaagtt atcacaccag atgatggtat
    20221 cttagctatc ggatcaggag ggaattttgc gttggctgca gcccgagcaa tgaaaaacta
    20281 tgctcaaaac gacatgagtg cgaaagaaat tgcagaaaat gcgttaaata ttgccgcaga
    20341 tatctgtatc tttactaatc ataatattat cgtagaagaa ctgtaagagg tgagtagata
    20401 tgtatgaatt aaaacaaaca ccaagacaaa tcgtaagtga attagatgaa tatatcgtag
    20461 gacagcacgc agcaaaaaaa tctgttgccg ttgctttgcg taaccgctat cgccgtttgc
    20521 agttagatga aaaaatgcaa caagatatta caccaaaaaa tatgctgatg atcggaccta
    20581 caggggtcgg taaaacagaa atcgcacgac gtttggcaaa aatcgtcaat gcaccatttg
    20641 tcaaagtcga agcaacaaaa tttactgaag tcggttatgt cggaagagat gtagaatcaa
    20701 tggttcggga tttagtagaa aatgcgatcc aaatcgtaga aaaagagcag tacagccgtg
    20761 tatacacaag tgctaaaaaa aatgcagaaa aacgtttggt aaaaatcttg gtacctggta
    20821 tcaaaaaaga acagaaacaa tccactaatc aatttgaaca aatgatgaat ctttttaatg
    20881 ctagtcagca aaataccgct gaaccgcaag aagaagtgac agaagatatt cgaatcaatc
    20941 gccgtacagt cttggaacaa ctacaaaagg gtttactgga tagtcgtgaa gtaaccattg
    21001 aagttgaaga ccaaaagaaa cctgcaccaa tgatgaacaa tggattggag caaatgggga
    21061 tcgacctaaa tgaaactcta ggtgctttga caccgaagaa aaaagtggaa cggacggtaa
    21121 cagtcaaaga agctttagag ttattgatca aggaagaatc agcaaaatta gtcaaggatg
    21181 ctgatatcca tagtgaggca atcaaattag cggaagaaag tggaattatt tttatcgatg
    21241 aaatcgataa gatcacttct aaatcacagc aatctggaga agtatccaga gaaggcgtcc
    21301 aaagagacat attgccaatt gtcgaaggtt cacaagtaaa cacaaaatac gggatcatcc
    21361 aaacagatca cgtcctattc attgcttcag gagctttcca tttgtctaaa ccaagtgatc
    21421 taattccaga acttcaagga cgcttcccga tacgggtaga attagatgat ttgacagctg
    21481 aagattttgt gaagattctg accgaaccaa ataatgcttt agtaaaacaa tacgtcgcgt
    21541 tgatcggtac agaaaatgtg tcagttacgt ttacaaaaga agcaattgaa cggatcgctc
    21601 aaatcgcttt cgatgtcaac cgtgacacag ataatatcgg cgcacgcaga ctgcatacca
    21661 ttttggaaaa actactagaa gatctattat ttgaagcacc agatatgcaa atgggagaaa
    21721 taacgatcac agaagcatat gtggatgaca aacttggctc aattgcggca aatgaagatt
    21781 taagtcgcta tattttataa aaaatcggag gacgacaatg acagacttgc taacgaaaac
    21841 ccgcaagata aacacacttt tgcagcaaaa gaatactttt gacatgcaag cagatttgcc
    21901 ttacgataaa atggctgtca cactaggtgg tattcttgac agcaacacct atatcatagg
    21961 aagtgacgga gtattactag gttataatga acgtcacgat gtgaacaatg aacgaatcaa
    22021 aacaatgttt gttgagaaac aatttcctga atcttatact gatacagtgg cacagttgat
    22081 gaaaactgaa gctaatatcc caattactag tgatattact gcatttccgg tagagtcaag
    22141 agagaaatat ccatttggtc tgacgactgt cgttccgatc tttggagctg gcgaacgttt
    22201 gggtacgatt atcttatctc gtatggaaca atcgtttgca gatgacgatc tagtcttagc
    22261 agaatatgga gctacggttg tcggtatgca gatcctttat cagaagtctc gaagcatcga
    22321 agcagatgta cggagtgcaa cggctgtcca aatggcaatc aacacattat cttatagcga
    22381 attgaaggct gtacaagcta tctttgaagc attggatgga gatgaaggtc gtctgactgc
    22441 ttctaatatt gccgatagta tcggcatcac tcgttctgtg atcgtcaatg ctttacgaaa
    22501 attggaatca gctggaatca ttgaatctcg ttcgttaggc atgaagggaa cttatttaaa
    22561 agtattgaat tcccgtttta aagacgagtt agcaaaacac agttattaga agtaagggga
    22621 ctggggcaga tagaaatgtt tgttccagcc ttcccatttt aaaaagtaag tcgaagttgg
    22681 aggaatggca atgactgtta ttattcaaaa tgaccagctg atcgccgaaa tcgctgaaca
    22741 cggtgcggaa ttgatcagtc tgaaatcaaa agaacatggt ttagagtata tctggcaagg
    22801 tgatccagcg tattggggca gacatgcacc ggttttattc ccttttgttg gacgtttaaa
    22861 agatgatcag tatgtttatc aagggaaaac atatcaaatg gggcaacacg gatttgctcg
    22921 ggatatggat tttgaagtca ttgaacatgg acaagaaatg gctagtttca tcttaaggag
    22981 tacgccggag acattagaaa agtatccatt tgattttgaa ttagtgatca gctatgaatt
    23041 aggaggagac ggcatcacgg ttcattatca agtggcaaat accggtgaaa aagaaatgtt
    23101 cttttctatc ggtggacatc ctgctttcaa tgtacctctt gaagaaggat tgtcatttga
    23161 agatttctat ctggcatttt ctccattgaa atcaagatta cgcctaccat tgaaaggccc
    23221 attcatcgat atggatcaaa agacgttagg tcagacaaat acgaatctgg ctttgaatcg
    23281 tgaacttttt gagcaagatg ccttggtttt tgaaacaagg ggtctaaatg cgtacgccat
    23341 tcgaagtgaa aaatcttccc atagcgtaac tttaagctat aaagatatgc cttatgtagg
    23401 gatctggtct ccttatccaa aagaagcgcc tttcgtttgt atcgaaccgt ggtgcggaat
    23461 cgctgacacg gtgaacagta gtggaaactt gatggaaaaa gtagggatca atcaactagg
    23521 tgcccatgaa atcttcaaga caaaatattc catcacagtg aagtaagagg ttgtgaccga
    23581 gaagttagca gggaacaccg tttaccaagg tgtgtaaaaa agctatcctg taagtaataa
    23641 gggagtgtga catcgattt
//
LOCUS       DAFEEZ010000042        23449 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000042
VERSION     DAFEEZ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.043"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="LP245_001784"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="LP245_001784"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBL1519706.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="LP245_001785"
     CDS             complement(1172..1867)
                     /locus_tag="LP245_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBL1519707.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="LP245_001786"
     CDS             complement(1880..2596)
                     /locus_tag="LP245_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBL1519708.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="LP245_001787"
     CDS             2926..3531
                     /locus_tag="LP245_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBL1519709.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="LP245_001788"
     CDS             3856..4179
                     /locus_tag="LP245_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBL1519710.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="LP245_001789"
     CDS             4361..5731
                     /locus_tag="LP245_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBL1519711.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5861..7162)
                     /locus_tag="LP245_001790"
     CDS             complement(5861..7162)
                     /locus_tag="LP245_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBL1519712.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7392..9350)
                     /locus_tag="LP245_001791"
     CDS             complement(7392..9350)
                     /locus_tag="LP245_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBL1519713.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9527..9793)
                     /locus_tag="LP245_001792"
     CDS             complement(9527..9793)
                     /locus_tag="LP245_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL1519714.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="LP245_001793"
     CDS             complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="LP245_001793"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBL1519715.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="LP245_001794"
     CDS             complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="LP245_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBL1519716.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13137..13700
                     /locus_tag="LP245_001795"
     CDS             13137..13700
                     /locus_tag="LP245_001795"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBL1519717.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13953..14474)
                     /locus_tag="LP245_001796"
     CDS             complement(13953..14474)
                     /locus_tag="LP245_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBL1519718.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14477..15319)
                     /locus_tag="LP245_001797"
     CDS             complement(14477..15319)
                     /locus_tag="LP245_001797"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBL1519719.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15312..16037)
                     /locus_tag="LP245_001798"
     CDS             complement(15312..16037)
                     /locus_tag="LP245_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBL1519720.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16213..16509
                     /locus_tag="LP245_001799"
     CDS             16213..16509
                     /locus_tag="LP245_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519721.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17077..18669
                     /locus_tag="LP245_001800"
     CDS             17077..18669
                     /locus_tag="LP245_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL1519722.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18682..19422
                     /locus_tag="LP245_001801"
     CDS             18682..19422
                     /locus_tag="LP245_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL1519723.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19590..20939
                     /locus_tag="LP245_001802"
     CDS             19590..20939
                     /locus_tag="LP245_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1519724.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21067..21657)
                     /locus_tag="LP245_001803"
     CDS             complement(21067..21657)
                     /locus_tag="LP245_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBL1519725.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21804..23156
                     /gene="brnQ"
                     /locus_tag="LP245_001804"
     CDS             21804..23156
                     /gene="brnQ"
                     /locus_tag="LP245_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBL1519726.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6710 a         4728 c         4468 g         7543 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttttctt ttattctatt tttctttccg
     5881 tggactctac tttgaaataa tcgatatgtg catgctggta ttctaatacc gtgaaacgga
     5941 atgatgcaat ctcaatgatt gttcctgctt ttatttcttt atatcggcta gaagcaaagc
     6001 ccgcaagtgt agtaaaattc gtttcttcaa actctggaat ctctacatga aaataacgct
     6061 ggaaatcatc taatgttagt ttgccggaga tgatataaga gccatctgac tgttccgcta
     6121 tcaatgcttc gtccaaatct gtctcatctc ggatttcccc gacgatttct tctaaaatat
     6181 cttcaatcgt cactaagccg cttgtccctc cgtattcatc ttttaagata gcaatatgct
     6241 ttcccttttt tcgcatgatc gtcaataatt tttttatagg gatcgtttca gttgttacga
     6301 tcggctcttc aatcaactgt tctactgtca gctggtcatc tttataagat tgcttgatca
     6361 aatctggcaa ggtgacataa cctaaaacat tgtcttttga ttctaagata accggatagc
     6421 gagtatgtcc ttgttcaatc gaagctttta tcgcttcttt gacggtttct gaagcttcga
     6481 atacttgcat ggacgtacgg tctacttgta tatcttttgc caaggtatca tcaaattcaa
     6541 acacgttttc caaataatga tattcttctt tggtcaactc tcctttttca taagaattca
     6601 atgcgactaa tgtcagctct tcttgagaca atgtctcttc tccttcagat acgagacgca
     6661 cacctaatag cttccctagc cctgcagctg aatgattcaa tacccaaata aaaggaaaca
     6721 ttactttata aaaataatga agtggtttaa ctacgaacaa gacgaccttc tccgtattga
     6781 cgatactata gctcttagga agcagttcgc caataaccac atcgatatac gtaactaaaa
     6841 taaatcccag cgccacagag attgtactgc taatagccga actaaaaggt agtttaccga
     6901 tcactggttc tagtaaagcc gcgacagatc cttcaccgac ccacccgatg atcaaaccgg
     6961 ttagcgtaat tcctaattga ctagctgata aatagttatc taaatggtgt gtaacatgaa
     7021 gagctagctt ggcgttcttt acattttcct tttctagttg ttccaatctt gatcgtctga
     7081 ttttcactaa agcaaattca cttgctacaa aaaatgaagt aattgcaatc atcaaaaata
     7141 aaataatgaa attgataacc atattctccc gcctttctct ttttctattg tacccttttt
     7201 ctacaaaaag attgaaaata atgcgtattc atatttagga ataaaaaagg agatgcggca
     7261 tttttcagcc acatctcctt atcacttcaa aatcattgcg ttacttgttg ctaaacagct
     7321 ttttcatgac ctctgataaa cggtgttcaa gtagctgaca ttcgacatta gttcaggtca
     7381 aagcgctact ttcacaaccg ctctttcaac catgttttcc gagtatttcc aatgataagc
     7441 ggaacagttt catgttttac ttcgctgtac tctagcccaa accatgtttc tggcgaggta
     7501 gcgatttttt tgattgccag ttttgcctgc atgatttgac gttgccattt tcctagagtt
     7561 gtcacattgg aaactacttc atcaatcagg acaaattgga aatcgccaac ttctcgccct
     7621 ggtgtcagag agtatctttg tggctgtttt ggcaaacggc cttgtttcat caaatcatgg
     7681 atgacttggc gaacatatac gttgatttcc tgttggaccc tgaaacctaa gaacagattc
     7741 acttggacaa taaaatcagt gtccatcata tctacttgat attctttcgt atatggctca
     7801 tccgtcactt ccacatgaac aaaccaatag actcgtgctc ttttaggccg tttatctaaa
     7861 atcgaataga tgaactgtcg gccaacttta tcttcagcca tatcaggaac caagaagacc
     7921 acatttgtct gatagattgg taaagaagta tcatcacgta attctctaag ctgcgggata
     7981 taatctctca aagacacatc ctcggttgac gattcgcgaa taatgttccc ttgttcccaa
     8041 ataaacatca cgactaagat gatcaaacca atcagaacgg ctacaaaacc gcctcggaag
     8101 aatttgacaa cacttgagat aaagaaaacg acttctatcg caccgaagaa aaaggtaact
     8161 aaatatgcaa gccaacgaga atgcccattt tggataagat aaaagtaaag cagtgctgtt
     8221 gtcatcaaca tcgtcacagt gatcgataga ccgtaagcag cttccatatg atgagacgtt
     8281 cggaatgtga caaccactag agaacaggcg atccataaaa tcagattgac tgctgggata
     8341 tacatttgcc cgatactgtt cccaggatac atgatcttta accgaggcag cagtttcaac
     8401 ttgattgctt ctgaaactag cgtaaacgaa cctgtaatca atgcttgcga agcaatgact
     8461 gcagcgactg ttgcaaaagc aacgccgatc acgatccaac tttgaggcat catttggaag
     8521 aatggattca ggttcttgat ttgctgtgct tcagggtttt gataaacatt caacaaccac
     8581 gcagcctgcc caaaataatt gataaccaaa caaattttga cgtaaggcca gctcagacga
     8641 atatttcgtt tgccgacatg tccaagatcg gaataaagcg cctctgcacc tgtcgtagcc
     8701 aggaaaatat ttccaagaat gaacaagcct aatttgttat ctgcactaaa aagcagctgg
     8761 atagcataat aaggattcag tgcacggata actgtccagt cttgactgaa gttcattaat
     8821 cccattacgc ctaaaaaagt aaaccaagcg aacatgattg gtccgaatgc ttttccgaca
     8881 atatctgtac caaagcgttg gaccatgaat aaaacaaaaa taataactaa agtgataatg
     8941 acgatcacgt tctggttatt accgaaccgg tcaaaaaact gcggaattcc tcgcaagcct
     9001 tcaatcgcag tcgttaccgt cacagcaggg gtcaataccc catctgctag taaggcagct
     9061 cctccgatca ttgcaggaat gatcaaatat ttcccacctt ttcggacaag tgtgtagagt
     9121 gagaaaattc caccttcacc atggttatct gcattcaatg caatcacgac atatttgatt
     9181 gttgtcagta gagtcaatgt ccaaaaaatc aatgagactg atccgataac aaaatcagga
     9241 ttgattcctg acaatccgcc attatcttca acaatcgatt tcataacgta aagcggactt
     9301 gtcccgatgt ctccgtagac gactcccatc gctacaagca ggccagccat tgatatcttt
     9361 ttggtattgt gcgttgttgc cacgtttttc cctcatttct tgttatatgg atatccttta
     9421 ggtaagcttg aatgatagat gatattctta tccatgacac ccgctttcct aaattgcttc
     9481 taattatcca agtaacacac tgaagtgtca acttatttga ataaaattat tctttctttg
     9541 gacgttctct gatacgtctt gccacaaatg aataaagagc aaggcaaaaa attgcaccca
     9601 ataatgctgg tatcaaataa aaaccgccga gttccggtcc cagtggtcct agtaaaaatt
     9661 cgccgagcca actacctaaa aaaccgataa tgatatttcc agatacgcct cccgggactt
     9721 cctttcctaa aattgcgcca gctatcaaac ctaatatacc gccgataaat aacgaccata
     9781 aaaaattcag catctccttt ccctccttta tccatatttc tcacttttat tttacgcttt
     9841 attcagaagg actccaaaaa tatgcgccaa gaaactccag aaaaaaagaa gttgtaacaa
     9901 aagtgttcag cttatttccg tagaagctgc ttctggaaca ccgtgaatca gaggttgtga
     9961 aatcagcggt ttgacctgag tattagagaa acaaacggaa aaatagttcc tcatattttg
    10021 ccgttttttg agctaatatc gagggacagc tgattgaaca tcgtttattg gagaggttgt
    10081 aaaaaagctg ttctgcatca agtaataaga acagccaagt aaaaacagct cctaatgttt
    10141 ttaacttggc tggacttatt accgcagatg caagcttttg aacaccgttt attcgaaaaa
    10201 aaaggactgt gacacggctt ttgtcacagt cccctttttt cgaataatta ttgtccccct
    10261 gtcaccttca cgatcacaag tacattattc ctatgaatta aattattttt cttcattttt
    10321 cgttgaacca tcttcgttca acattgcttt tcttgacaga tttacgcgtc cttgtttatc
    10381 gatttcagtt actttcacaa ggatctcatc acctagttta acaacatctt cgactttatt
    10441 gacacgatcg tttgctaatt gggaaatatg gacaagtcca tcttttcctt tgatcaagtt
    10501 gacgaatgca ccgaattttt cgatacggac aactttccct agataaactt caccaacttt
    10561 gacttctttg gtcaaatctt cgatgatctt gatagctttt ttgatcattt ctgcatcagc
    10621 tgaagcaata cttacttttc catcttgatc gatatcgatt ttcacaccag tttcatcgat
    10681 gattccgttg atcgtatcgc cgcctttacc gataacatct ttgattttag caggttcgat
    10741 ctggatcatt tcgatttttg gtgcatattg gcttaattct tcacgtggag cagcaatcgt
    10801 tgaagtcaat tcttctaaga tttccatacg tgcttgtttt gcttgagtta atgcttcagt
    10861 taggatttgt tctgtgattc cttgaatctt gatatccatc tgtaaagcag tgataccatc
    10921 ttttgtaccg gcaactttaa agtccatatc gccaagatga tcttccagcc cttggatatc
    10981 agttaggatc gtatagtttt caccatcaga aacaagtccc atcgcaatac cggcgactgg
    11041 cgctttgatt ggtacacctg catccatcaa tgctaatgtg ccagcacaga tacttgcttg
    11101 ggaagaagaa ccatttgatt ccaatacttc tgctactaaa cggatcgtat aaggaaattc
    11161 ttcttctgaa gggattactt gtgctaacgc acgttcacct aatgcgccat gtccgatttc
    11221 ccgacgccct ggagagcctg cacgtcctgt agaaccaaca gaaaattgag ggaaattgta
    11281 gtggtggatg aatcgtttgc tgacttccac ccctaaacca tcaatgattt ggtgctctcc
    11341 tagaggtgcg agtgtacaag ctgataaagc ttgtgtttgt cctcgtgtga acaaacctga
    11401 tccatgtaca cgtggcaata agctgacctc tgatgacaat ggacggattt catccaattt
    11461 acgcccgtca ggacggatct tatcgatggt gatcaattca cgtacgacat ctttttcaag
    11521 atcttctgtg atttgtttaa cttctttcaa caagtgatct tcatcttcat gacctgcaaa
    11581 tttctcagca taagcttcgc ggatatcgat cttcacctgc tcgatattat cttcgcgagc
    11641 aagtttttct tcagtcatta ctgctgcttt cattgtagcg taagaagcat caaagatttc
    11701 ttttttcaat acttcatcaa cttgcagtaa agtcacttcc attttttctt tccctactgc
    11761 ttgaacgatt tcttcttgga aagcaactaa ctctttgata gcgtcaaaac caaacagcaa
    11821 tgcaccaagc atgtcttctt ctgaaacttc tttcgcgccg ctttcaacca tattgatggc
    11881 ttgtttcgtt ccggcaacag tcaattcgat atctgtttgt tctgcttgtt ctactgttgg
    11941 attcaagacg tactcgccat ttacacgacc aacttctacg cctgcgattg ggccgtcaaa
    12001 tgggatatct gagattgata gtgctaaaga agaacctagc attgctgcca tagctggcga
    12061 gcagtctgtt tctacactca tcacgatgtt cgttacttgg acttcattac ggaagccttc
    12121 tgcaaacatc gggcgaattg gacggtcgat caaacgggca gtcaatgttg cttccgtact
    12181 tggacggcct tctcgtttga tgaaacctcc agggattttc cctgctgcat acattttttc
    12241 ttcataattg atcgttaatg ggaaaaagtc tgtatctttt gcttctttag aggccacagc
    12301 tgcacttaag actactgtat ctccataacg gactaaaacg gctccgtttg cttgttttgc
    12361 tagctgaccg acttcgattt gtaagggacg gccgccccat gtcgttttga atacttgttt
    12421 ttctgacata acttctcctt ttccttctcg tgaaagcaag acgctactaa acaaatgaaa
    12481 actgccgaaa gccgtctttt gagcagcttt catttggtta gtaggagtcc atctagcttg
    12541 atcacggaat tttacttaat tgatatacga gtaaaaaaag tgagattcat gtgaatccca
    12601 ctctttttga ctaaaattaa cgacgcaagc ctaaacgttt gatcaattcg cggtaacgtt
    12661 gaacgtcagt tttacgtaag taagctaaca agttacggcg gtgaccaact tttttcatta
    12721 ggccgcggta tgaatgatgg tcttttttgt gcacgcgtgc atgttcattc aagtggttga
    12781 tttcttcagt taatacagcg atttgtactt ctggagaacc agtatcccct tcatggcgag
    12841 cgtattcgtt gatgatttca ttcttgcgtt cttttgaaat tgccatttct ttcacctctt
    12901 tcgattattc ccctgcgact gagtaaaacg ttggtgattc gcttaaccaa gtggcaggtc
    12961 atgtgcctag agcacacagc tatactttac ctgaaaccgg gttgaaaatc aagtagttaa
    13021 tcattaagaa aaggtagttt tcaaacaatc ttactactac ttttccattt ttgtggtaaa
    13081 ctataatgcg aaaatagact tgaaacacag tcttttaaga aaggggtaca tattccatga
    13141 ttacaatgga tgatatcatt cgtgaaggaa atccgacctt acgcgaagtt gcaaaagaag
    13201 tttctcttcc attaagcgaa gaagatatct ctttaggaaa agagatgctt gagttcttaa
    13261 aaaacagcca agatccaatc aaagctgaag aactacactt acgaggcggt gttggcttag
    13321 ctgctcctca attagatatt tctaaaagaa tcattgctgt tcacgtacca agtcctgacc
    13381 cagaggcaga tggaccttct ctaagtactg ttatgtataa tcctaaaatt ttgagccatt
    13441 ctgttcaaga tgcttgttta ggggaaggtg aaggctgttt atctgttgat cgagaagtac
    13501 caggatatgt tgttcgccat gccaaaatca ctgtgtctta ttatgatatg aatggtgaaa
    13561 aacacaagat tcgtttgaag aattatgaat cgatcgtcgt tcaacatgaa atcgaccata
    13621 tcaacggtgt gatgttctat gaccacatca acgatcaaaa tccatttgca ctaaaagaag
    13681 gcgtattggt gatcgagtag agaattggca ggttccttcg atactatgct acaagaaagc
    13741 tttataaaaa aggggagtgc tcaaaagctg cacttccctt ttttatgttt ctccactaat
    13801 cgaaatttag atagacatct agaaatcgca attccaaaaa attctgtgta ttggatacgc
    13861 atcttttctt attttttctt atttcttcca tatgggtgtt tatctcagag atgatagaat
    13921 agtttctagg ataaaaagta gcagctacga tgttatcctt cgtagaggat tcctgcttca
    13981 gctagttttt gtttgatgtt tttcagcata tgcttttctg ggtagcggat cgtatgcaga
    14041 tggatgccgc ctgttaattc ggataacaaa gtagcattac ttttttgata acgtctcata
    14101 aaggaatcga tatcttgtgg cgttttgatg tgcaaagttc ctgctaactc accgtaaagg
    14161 ggatgttcca caattacatc aatgatttca ccaccatttt caacgattag tctcagttct
    14221 tcttctgttt gatcttttcc atgctggaca gcgattttac tgatgtgccc agtattggtt
    14281 tcttctgttt cgaggatata acctcttgct gttgccacga tacttttacc tgcagctcgt
    14341 agtaaagcaa tatcgcctac aatgatctga cggctgactc caaaagtttt cgcaaacttg
    14401 ctagcactca ctggtttttc tgtatttgcc aaggtttgca tgatttgttt tcgccgtgtc
    14461 tctccttcga tcacacttat tcctccttca ttttgttttg gtattcgcgc gagtgtttca
    14521 tcaaatcaac atacgtgtct gttattgttt ccttatatcc cttatttttc agcagactaa
    14581 caactttatc caatacttgc tgctctcttt ttgcatcata aactgcttgg ttttcttctt
    14641 ttttcacttg tcctatttta gttaccgtat ccattctttt ttctaataaa gcaaccaact
    14701 ctcgatcgat catatcgatc ttatgacgta atgtttcaag agactcttct gttagttctt
    14761 cctctactgt cttgatgata cgagcaggat ttcctgcaat cactacattg tcgggaaaag
    14821 atttggtcac aaccgaacct gcgccgacta ctacgttgtc ccctagagtg acacccggcg
    14881 tgacgataac tcctccgcct aaccaaacat tattaccgat tttaatgggt tttgcgtact
    14941 ccagaccgct gttacgtttc actggatgta gtggatgcgt cgccgtgtaa agctggacat
    15001 tcggagcgaa catgcagtta tcaccgattt caatcgtgct gacatctaaa aatgtacaat
    15061 tgaaatttgc ataaaaattc tccccaacaa atatattata tccgtaatca aaattgataa
    15121 ctggctccat atagattttt ttccctgtac ggccaaaagt ctctttcaac aattgggatc
    15181 gcagttccgc tgattctgct tggttgatga tttggctttg acttcttgca aacatacggt
    15241 cggcaaccag ctcaggatca ttggcaaaat aaagctcgcc tgcaatcatt ttttcttttt
    15301 cggttttgaa ttcagtcata atctgctcct aattcttgta tttttttgaa aacaaccgct
    15361 ccgtcttctt gaataaacgt ataaggctcc gctaaataaa caggcgtttg attgattact
    15421 aagattttgg ctgacggctg gcgaaactgt accagatcac aaaacggatg aacttgaaaa
    15481 ctcgttccaa caatgacgat cagctctgct tggctgacgg cataagccgc ctgctccatg
    15541 actccatctt gaaacccttc accatataac acgatgtctg ggcgtatttg tcctccgcat
    15601 gcttgatgtt tgtcgctgtg aagatattct ttccagtcta ccgtttgttg acattttcga
    15661 caatgacatt gatacagact cccatgaaaa ttgacgagtt gcgggctttt agcctttgcg
    15721 tgcaaaccgt cgatgttttg ggaaacaacc caaacatttt tttctttcgc tagatgtgct
    15781 atttccaaat gaatgatatt gggttttgct tcaggatgat aaatcttttt gacaaattga
    15841 tagaatttat ccggttcatt caccattgct tgatgactca gcaagtattc cggctgctcc
    15901 atcccgtggt agattcctga caaagatcga tagtctggca ctccagaagg tgtggatacc
    15961 cctgcaccgg tcaaaaatgt aatttgctga taagctaata tctcttttgc tgcttcgtct
    16021 actgttaatt gtttcatgtt ttgtcacctc actttccatt atagcccata ctcgaacaaa
    16081 tttattgttg aaaagtcaga aaaatgggaa taaaaaagtg ttatgggcat ttgagcaatt
    16141 tatcacaatg ttcactgaca aaagaatgaa aacgtgttac aatactgctg tataaaagtg
    16201 aggtgaatcg atatgttacc attctttatt tattggggcg ttattctggc ttgtatcgcc
    16261 tggttagcgt taagcgttta tttctctgtt ttttatcttg tacgcaaaga aaatggaaat
    16321 ctttgggctt ttgctttatt caacgtgatt gccgcaattg ttttagccat tacattagcc
    16381 gtatatcgaa catggggctg gggaatcacc caatactcaa gtttgattta tctaatatta
    16441 gccatttatg gcgtcgttgt tcttttgcaa gcgatcctag gacgtgagcc aaagaaagcg
    16501 gcagcttaaa tgatcgagat ggaactggac acaggaaatt ttctgttcta gttctttttt
    16561 tattgtatta catacatttt tgtgtataat tatactatcg tttgcaatgg atagatgatt
    16621 cacattttga ttgttttttc ggtaaaagta aagatttcta tatttatcag tattttttca
    16681 aaaaccagca gttatagatt gacaaagcct ctcgagtatc gtaaactttt tttgtataaa
    16741 taactgaata cgagatgcct caatcaatga ggtagaggtc gcgagaatca ttaaccctgt
    16801 ggagtgaagc aaacatggag aagcaggaat agggaggatc gccgaaatgt gcactttttt
    16861 gcttggagtg tatgttggga cgcaagttaa gagcttgcgg actgtcttag cagtgatgct
    16921 aagttgcgct atgttttgtg agaggtttat caccttatgg aattttagcg gcctttttat
    16981 atctataaat cggtcgcttt ttattttttc agataaagct ttaccgcatt tcatctagac
    17041 cgctcgtgta tcatataatc agaaagggag aaaaaaatga aaaaaaatat ggtttcagtt
    17101 gccgtactat ttgcttttgt cttctcacta ttcagtgtgg gatctctggc aaatgcagat
    17161 gaaaaaacac cgagcgatga gtttcgcgta ggtatggagg ctgggtatgc acccttcaac
    17221 tggtctcaac aaacagatga gaataatgcc ttgccaattc aaggccaaaa tagttacgcc
    17281 ggcggttatg atgttcaaat cgctaaaaaa gtagcagatg gtttagggaa aaaattagtc
    17341 atcgtccaaa cgaaatggga tggtctggct cctgcccttc aatcaggcaa gatcgacgcg
    17401 atcatcgccg gaatgagccc tactgctgaa cgacgaaaag aaattgattt taccgatcct
    17461 tattacgaat cacaattagt agtagtagtt caaaaagata gcaaatatgc aaaagcaaaa
    17521 agtttagcag atctttctgg agcaaagatc actgctcagt taaatacatt ccactatact
    17581 gtgatcgatc agataccaga tgtgcagaaa caacaagcaa tggataattt ctcagcaatg
    17641 agaacagctt tagcttctgg aatgatcgat ggttatgtca gcgaacgtcc ggaaggtgta
    17701 acggcaacta gtgtgaacaa agacttggaa atgcttgaat tcagcggtgc agatggcttc
    17761 cagacaaacc cggaagatgt tcagatttct gttggtatgc gtaaaggcga cccggatatc
    17821 caaaaagtaa accagattct ttctggcatc tctaacgatg aacgaaccaa aattatggac
    17881 caagcagtca aagatcagcc tgctgcaact gatagtgaag aaaaacctgg catcatttct
    17941 gatttcacta cgatttggaa acaatacggc aatatgttct tacgaggtgc tggacttacc
    18001 ttgttcatcg cattgatcgg gacagttgtc ggtactacac ttggattact gattggtgtc
    18061 ttccgttcgg tacctgaatc aggaaatgca ctgactcgct tcttccaaaa aatcggaaat
    18121 gcacttcttt ctatctatgt cgaagtattc cgcggaacac cgatgatggt acaagcaatg
    18181 gtcatcttct acggtctggc actcgctttt ggcatttcat tgaaccgaac gattgccgct
    18241 ttgtttattg tctctctcaa tactggagct tacatgacag agatcgttcg tggggggatt
    18301 tttgcagtag atgaagggca gttcgaagct gcgcaagcca ttggtatgac ccatggccaa
    18361 acgatgagaa aagttgttat tccacaagtt ttacggaata tcttgccagc aacaggaaat
    18421 gagtttgtta tcaatatcaa agatacagca gttttaagtg taatcggcgt agctgatttg
    18481 ttcttccaag gaaactctgc ttccggtgcg aatttccaat tcttccaaac atttacgatc
    18541 gtcgggatca tctacttagt catgaccttt acgatcacca gaatcctgcg ggcggtagaa
    18601 aagaaaatcg atggtccttc agcttatacc aagcttgaag aaatcgacaa ttcaaatttg
    18661 caggaataag gaggaagaat catgaatgaa aaaattattg aaatcaaaca tctaagaaaa
    18721 agcttcggtg aaaatgaagt attgaaagat atcagcgtaa cagtcaataa aggtgaagtt
    18781 gtgacgatca tcggttcttc cggttctggt aaatctactt tcttgcgctg tatcaattta
    18841 ctggaaaaac caacaggcgg cgagatcatt tataatggag aaaatgtatt agctcctaaa
    18901 tataatttac ctaaatatcg aacgaatcta ggtatggttt tccaatcctt caacctgttc
    18961 aacaatatga atgtcttgga aaactgtatg tctggtcaaa caactgtcct gaaacgagat
    19021 aaagaaactg ccaaaaaagt agcaatcgaa aatctggaaa aagttggtat ggatcgttat
    19081 atcgaagcca aaccagcaca attatctggt ggacagaaac agcgtgtcgc aattgctcgg
    19141 gcattatcaa tgaatccaga tgtattgcta ttcgacgaac ctacttcggc gttagaccct
    19201 gaaatggttg gcgaagtgct taatacgatc aaagacttag cacatactgg cttgacaatg
    19261 cttatcgtga cgcatgagat ggaatttgca aaagatgtat ctgaccgtgt catttttatg
    19321 gataaaggtg tgattgcaga agaaggtaca ccagaagata tctttgtcca tccgaaagaa
    19381 gaacgtacaa aagaattcct ttcacgtatt ttaaatgctt aggatcaata gctgattggg
    19441 acaaagagct gcggtgttta ccgcagttct tttttatgaa ttactcataa aaggtaaatt
    19501 tctgaaaatt ttggaatctt agttgtgttt ttcagaaaac tctcttaata tggaagtaat
    19561 taaacttttt tagttaggat gatttaaaaa tgaatgaaga gcaagaactg cagcgtggac
    19621 tgaaaaatag acatgtccaa ctgatttcta ttggcggagc gattggaacg gggttgtttt
    19681 taggttccgg aaagtctatc cagctagctg gcccttcgat attgctcgcc tatcttatta
    19741 ctggatgcat ctgttttttc attatgcgtg cgttaggcga acttctgtta tcaaacacca
    19801 ataaccattc ttttctggat tttgttgcag aatatcttgg caaaaaagcg gctttcatca
    19861 ctggctggac gtattggttc tgctgggtat cgattgcaat ggccgattta acagccatcg
    19921 gaatgtatgt acgctactgg gcgcctggtg ttcctcagtg gcttcctgaa ctgattgcat
    19981 taggtcttct tctttgcttg aatatggtgg ctgtctcatt gtttggtgag ttagagtttt
    20041 ggtttgcatt gatcaaagtt gtagcgatca ttgcctttat cctcgtagga gcttatatga
    20101 tcctcaccca ctatacgaca gatattggca cagccagtat cacgaatcta tggtctcatg
    20161 gcggattctt tccaactggt gcaaaaggat ttatcttagc tttccaaatg gtaacctttg
    20221 cttttgctgg gatagaatta gttggattag tcgctggaga aacagaaaat cctgaaaaag
    20281 tgttgccgga agctatcaat aatattccta tcaggatcat cttattttac ttaggatctc
    20341 tttttgtcat tatggcaatc tatccatgga acagcttgaa tccagataac agtccatttg
    20401 tagaagtatt ttcggaaatt gggatcacga ttgctgcttc cttgatcaat ttagtcgtat
    20461 taagtgcagc agcttctgcc tgcaacagtg caatatatag tacaggacgt atgcttcgtt
    20521 ctttagcgca agaaggcagt gcccctaaaa aattcaaaaa gttaacaaca catcatgtgc
    20581 cagggaatgc tttgacattt tctactatcg tcattttcat ttctgttatc ttgaattacg
    20641 tgatgcctag tgaagtattc acactagtaa gcagtattgc cactacttgt ttcttgttta
    20701 tctggagtat gcttgtctac acgcacatga aatatcgtaa aagtatcctc ggcaaaaaag
    20761 ctcattcatt taaaatgccg ttgtacccat ttagtaatta tctggtattt ctttacatgg
    20821 cctttgtgtg tgtcgtcttg ttcctaggaa aagatacgag aatcgcttta ttactaacac
    20881 ctgtgtggtt cttgcttcta ttactaatct atcatatgaa atatgaacgt aagaagtaag
    20941 aaagtagttg tgacagaagt ggtcagcttc gagaaataag aaggaattta cgaaaattgc
    21001 ttcttaaatt tttgtgaaat ttcggcttat ttcttggaga taaaagcttc tgtcccagcc
    21061 tcttttctat ttccccggaa acaaccgctg ataataggca tctgcttttt tataggaaaa
    21121 aatccaaata ccagatacaa aaaaacgtcc gaataacccg atcaacggta caaaaaagac
    21181 accggcaatc aagcataagt taatcatcat ggagataaga cttcgacggt cctttgacaa
    21241 aactctcacg acatgggaat ctggtttatt tgctttcatg atttgcctca tcaagatacc
    21301 aaaagaaaaa ctccacatcg tgtatactaa gacataagcc atctcaggcc aaaaagcttc
    21361 agggttacgc ccgacccaac tagtaacaga aggacataaa gtcagccaaa agagcaaaaa
    21421 gatattcgac cagaccactc ggtaattaat tcgttctgcc atctgaaata tacgatgatg
    21481 gttcacccag atcaccgcaa caaatataaa gctgatggta taagctaata atgtatttcg
    21541 gatgacccat aaagaatgaa agctagatgt attagggatc ttgatctcta atacaataac
    21601 tctcaaaaca atggctacca ctccatcagt aaatgcttct aatctcgact ttgtcacgat
    21661 gattcctcct cagatgattc agcgctttta ttttatcact tacgttatta aataaccatc
    21721 gttttatata gggaattttc tgaaaattgt tgcatatttt tcgaaatttt gttactttta
    21781 aaaaaaccgt aaaggagtta tgtatgacaa aaaaattatc atttaaagac tatcttttta
    21841 taggctccat gcttttcggt ctattttttg gtgctggaaa tcttatcttt cccgttcatt
    21901 tgggtcaaga agcaggcgct gctacctttt gggcgaatct aggtttcttg gttaccggta
    21961 tcggtcttcc cttcttaggg gtgattgcca ttggtgtatc gaaaagctca ggtgtatatg
    22021 aattagcaaa acggataaat caaacatatg cgatggtttt taccatcttg ctttacttag
    22081 ttatcggacc gttttttgct ttacctcgcc ttgcaaccac atctttcgag attggtttag
    22141 caccatttat cgatcctagc agacagacgc tatatctagc aattttcagt attgtatttt
    22201 ttgtgctggc ttggtggttt tcaagaaaac cgacaaagat attagattat gttggaaagt
    22261 tcctgaatcc tgcatttttg gttttattag gtgctttgct tctccttgct tttttgaatc
    22321 cactaggttc tgtaaatcaa gcgcctattc agccaaatta tcaagagcat gcttttttca
    22381 cagggtttac tcaaggatat aacacattag atgcgcttgc tgctttagca tttgggatca
    22441 tcattgtcac aacaatccaa aacatgggtg taacaaaacc tgctgaaatc gctaaagaca
    22501 cgatcaaatc tggtgcgatc agcattatat tgatgggaat catttatact ttgctcgctt
    22561 atttaggtgc tatgagctta ggtagctttg ctctaagtga aaatggcggg atcacgctgg
    22621 ctcagattgc tgatcattat ttaggtactt atggcagtat cttattagca tttatcgtta
    22681 tattagcttg cttgaagacc ggtattggtt tgattacagc ttttgcagaa acattcacag
    22741 atttgtttcc gcaaagaaat tacgcattct ttgttgcact tgctagtatc cttccttgtt
    22801 tagcggcaaa cgtaggcttg acgaatatca ttcaattttc gttgcctgtt ttgatgttca
    22861 tctatccatt agcaatgaca ctgattttac tagtgttagt tggtcctttg tttaagcagc
    22921 gtacggctgt ttatcgaatg actacttatt ttacattgat tgcttcgatt tttgatgggt
    22981 tgaacgcttg cccagaaact atcaaacaaa cacctattgt tcaaaatctt ttatatgttg
    23041 cggaaagcta cttgccgttt ttcaaattgg ggatggggtg gatcgtacca gcagttatcg
    23101 gttttgttat cggactgatt tggagtttcg ctaagaaaga agaagtagca gattgataaa
    23161 agaggttgtg aaagagacgt tcagccttga gcaataaaaa gtaattttga aaaatggctt
    23221 ctcacatttt tgcataaatt tgacttaata ccgagaaact ggcttttgaa caccgtttat
    23281 tgagcgtcta taaactgacc tgagtattag agaaacaaaa cggcaaagta gctccatata
    23341 ctttgccgtt ttgttttgaa ctaataccga agagaagctg atcaaacaac atttctttta
    23401 taatatagat tttagacata tatatgatat aaaaatagtt ttcgcaaaa
//
LOCUS       DAFEEZ010000043        23328 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000043
VERSION     DAFEEZ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.044"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..209)
                     /locus_tag="LP245_001805"
     CDS             complement(<1..209)
                     /locus_tag="LP245_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL1519727.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSD"
     gene            complement(308..622)
                     /locus_tag="LP245_001806"
     CDS             complement(308..622)
                     /locus_tag="LP245_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519728.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(690..1184)
                     /locus_tag="LP245_001807"
     CDS             complement(690..1184)
                     /locus_tag="LP245_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519729.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            complement(1177..1491)
                     /locus_tag="LP245_001808"
     CDS             complement(1177..1491)
                     /locus_tag="LP245_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519730.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            complement(1707..3098)
                     /locus_tag="LP245_001809"
     CDS             complement(1707..3098)
                     /locus_tag="LP245_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBL1519731.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            complement(3083..3694)
                     /gene="mobC"
                     /locus_tag="LP245_001810"
     CDS             complement(3083..3694)
                     /gene="mobC"
                     /locus_tag="LP245_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBL1519732.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            complement(3698..3895)
                     /locus_tag="LP245_001811"
     CDS             complement(3698..3895)
                     /locus_tag="LP245_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519733.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            complement(3886..6564)
                     /locus_tag="LP245_001812"
     CDS             complement(3886..6564)
                     /locus_tag="LP245_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519734.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            complement(6551..6769)
                     /locus_tag="LP245_001813"
     CDS             complement(6551..6769)
                     /locus_tag="LP245_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519735.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            complement(6845..7897)
                     /locus_tag="LP245_001814"
     CDS             complement(6845..7897)
                     /locus_tag="LP245_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL1519736.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDNSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            complement(8050..8376)
                     /locus_tag="LP245_001815"
     CDS             complement(8050..8376)
                     /locus_tag="LP245_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519737.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            complement(8388..8588)
                     /locus_tag="LP245_001816"
     CDS             complement(8388..8588)
                     /locus_tag="LP245_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1519738.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            8711..9313
                     /locus_tag="LP245_001817"
     CDS             8711..9313
                     /locus_tag="LP245_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1519739.1"
                     /translation="MEFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDKIVKNIAS
                     LDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKA
                     LNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            9368..10534
                     /locus_tag="LP245_001818"
     CDS             9368..10534
                     /locus_tag="LP245_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1519740.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            10951..14178
                     /gene="fss3"
                     /locus_tag="LP245_001819"
     CDS             10951..14178
                     /gene="fss3"
                     /locus_tag="LP245_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBL1519741.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVNCTVERHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            14291..14605
                     /locus_tag="LP245_001820"
     CDS             14291..14605
                     /locus_tag="LP245_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1519742.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            14618..14992
                     /locus_tag="LP245_001821"
     CDS             14618..14992
                     /locus_tag="LP245_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1519743.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            15002..15337
                     /locus_tag="LP245_001822"
     CDS             15002..15337
                     /locus_tag="LP245_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBL1519744.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            15420..16436
                     /locus_tag="LP245_001823"
     CDS             15420..16436
                     /locus_tag="LP245_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL1519745.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFPDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            17030..18904
                     /gene="ltrA"
                     /locus_tag="LP245_001824"
     CDS             17030..18904
                     /gene="ltrA"
                     /locus_tag="LP245_001824"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL1519746.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            18976..19350
                     /locus_tag="LP245_001825"
                     /pseudo
     CDS             18976..19350
                     /locus_tag="LP245_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346898.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            19445..20120
                     /locus_tag="LP245_001826"
                     /pseudo
     CDS             19445..20120
                     /locus_tag="LP245_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            20113..20277
                     /locus_tag="LP245_001827"
     CDS             20113..20277
                     /locus_tag="LP245_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519747.1"
                     /translation="MTDKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            20353..21495
                     /gene="dcm"
                     /locus_tag="LP245_001828"
     CDS             20353..21495
                     /gene="dcm"
                     /locus_tag="LP245_001828"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HBL1519748.1"
                     /translation="MRFLDLFAGIGGFRLGMEQASHHCIGFCEIDKFARRSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AALLRPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYIPQSRERI
                     FLIGHSRDACTEQVFPIIGPSSTSDQNIRNLVNINPSNRGMGGQVYGSDGVAPTLTGD
                     EGIKIALPARDGISVAGLLPGKFEQGNRVYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAIVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVQKCDL"
     gene            21485..21775
                     /locus_tag="LP245_001829"
     CDS             21485..21775
                     /locus_tag="LP245_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519749.1"
                     /translation="MIYDELVGEIYWVIEKIQSDPELEEQLRRLNFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            22033..23217
                     /locus_tag="LP245_001830"
     CDS             22033..23217
                     /locus_tag="LP245_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL1519750.1"
                     /translation="MVQQNLDYRLLKDRRNQYGVSQNKLATACGLSRPYLNQIENGGV
                     TTSTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVQKIVQEILHLKFDYMLHED
                     YAFYSYQEQYIMGDIVVMLSHEEEKGVLLELKGRGCRQFETFLLAQKRSWYDFFDDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDKSETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIEGTTFSIINRYLRFTDKVEGKRRTNWPLNERWGRFIGRNRKEIQLTSDPKPYT
                     IERTLSWLGRQVAPTWKMAKELDRLNQTTYILDMVQNAQLSDRHKKILEQQSMAIENL
                     II"
     gene            23214..23312
                     /locus_tag="LP245_001831"
     CDS             23214..23312
                     /locus_tag="LP245_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBL1519751.1"
                     /translation="MKRGSSMLGITVMCLIHTSAAADRVMERKVIK"
BASE COUNT         7532 a         4095 c         4217 g         7484 t
ORIGIN      
        1 aaatcagata cataagccca tgtacccgtt cgttgtaaat aaagttcttc ttgtaacaac
       61 tcccattttc tcttagaaat cataatgacg ccatcgttca atccattttt agaatcccta
      121 gtaatttcta tttcagaatt tgaatgaact acttcttgca acactttacc tatattttct
      181 ttgaagtttg ttggagtaat agtatccaaa atgaatacct ctcttctcta tacctctatt
      241 atgaagtgcc cataaaataa agcaagcgtt gaggaataat tctatcaaca cttgctttat
      301 taagctttca ttttgtagtt tgactaaaac caataatctt atttctaaac tctcgaaaaa
      361 cttcttgtgg ttgataatag tctggatcta tttcaaatgt ttgtgagaat aattcattga
      421 atttttctac tgaaataatg attttaccat tcttctctcg actgttttct attatttctg
      481 cttctaattc aaataaatct agtgacgaac taaaatcata aatcatgtca tattgaataa
      541 aaaaatcaag aaaaagttgc tcaaactctt ccttatttat cactaatgtt tcaaacggaa
      601 caactttatt ttcctcagcc attctcccag ttccattttc aaaaatcaca aaactgatat
      661 taccttaaaa actactaaca aaataaaact tataaagtaa atggcaaccc aactatgtaa
      721 ccattctctc tacgtactac gatttggtag tcctgccttt caatcggtaa ttcataatag
      781 taatttactg tttcttcttt gccactttca atatactctg gattatccaa tatcatatca
      841 tactcataaa gttcttcacc atccttattt tcaatcgacc attgttgtgg acgtatcgga
      901 ttttctgtat catttataag tgtataggtc acttgtaata cacgatcatg ttgtgcaaat
      961 tcatttcttt tttcggtcac ttcaatattt ttaaatgtta gttcaacccc atctgcctga
     1021 taagtttcac ctatttttaa atcttttgtt acaattttta ttggcttttc ttctggaaaa
     1081 tgtctggctt taattgttag ataacttcca aaaagaatca atcctagtag cactaaaaga
     1141 attcctttaa cgagccactg aaacgggaag taaactttaa acatcttttt tctcctccgt
     1201 tttgtatttg ttttttagag aatacgataa cttttgatca atgtcatcca gcttttcaat
     1261 tacttcatta cttatcattg attctagttc tgaaattttt tgttcaaatt taatgctttc
     1321 aggatcatta aatttattat ttgatggact agctaacact ggtaaatttg aaaccataac
     1381 acgaaacata tttgcctttg aaccaaaaat tcctttgttt tggttgtaaa aattgttgaa
     1441 tatttcttta gtttcttctg aagccgagac tttaaaatat ggatagttca tttttttctt
     1501 ccacctttct ttttttggga gggagtctgt agggagcttg ctccctcaga gatttacccg
     1561 ccatctgact tgccagaaag tagcctagcg tgagcggggc ggattgactg gcaagtagat
     1621 gggtagctgg cgtatgtcct aaaaactgct tctttccaag caactcttca taggcaaaaa
     1681 actggaaagt ccactaacaa gcccattcag aattccattt caaaattttg ttgccttttt
     1741 tgctgatttt caatcatttg ttgtgtgaat tcataatcct ttttagcacg atacattttt
     1801 acatcgtcat tcattatgcg actgatttga tagtgaatct gtttagcaga aggtgtatga
     1861 gaacaatttt caaaaccctt tgccggtaga aataactctt tctgatcagt ctttttaata
     1921 gaaattgttt tacttttcgc actacgtaaa gtttgaggat tcacatccgt atgaagttta
     1981 atcgtgtatt cttgatcatc ttctaaagac attgtattta caaaatgctt gtctacctct
     2041 cgcaagaagt catcatattt aatgaatttt tcatcgcctt cacggtcgct aaattgcttt
     2101 tgtgcgatgg aatctaattc cacaaacggt acatttaact caccagtttt gtaatttact
     2161 ccactaatta gcgacataac ttgctctctt tccatattaa aaaaattttt tatatgtgat
     2221 tcttctaaat tcttttcaag ttgttcagaa acagattcaa atgaatatct tttccctaac
     2281 tttcttgcac taaaagtacg ttcgacatac tgactttttt cttttctaga ttgtttatct
     2341 cttcctaaag taattaactc acctctacgc tcatagaaat ttacaccttg tttgtaaaga
     2401 acatagccaa gtttgttatt tgtttttgaa aattgataaa cttcaatgtt atattctttt
     2461 gccaaatgat ccgaaaaatc ttcaaaagaa ttcacttcgc atttttccaa cgttgcttcg
     2521 atcgcatttt gcacaaactc ttgataatta atttttccat atttcatctt agaaggatcg
     2581 tttgaataaa gattggttct cttttctaag ttttcatagt actcattatt cactgattca
     2641 agaccatgtt cattgaggac ttgatcgtta atttttcgca ttagttctaa atctttaggg
     2701 tcaatacgca accttttaca tgtttccatg ttaatattat taatgacaag atgactatga
     2761 aaatgatctt tatcattgtg acttgcaaca atgatttgcg aatttggaaa agctttctct
     2821 gcaaattcga cagctatttc gtgcatttta tcaatactta actctttaga agtactctta
     2881 tcaaacgaat gaataacatg aaacgcttgt gctatatctt tagatttatt catcttggta
     2941 cgtactaaat tcatttcttg cagtgcttcc tcactatcat cactacaatt tattcctgag
     3001 actgcaacac atttttcttt ttttgaagga ttagctgcat attgtaatag cgaggataaa
     3061 tttttcttgc gtcctttcga tgttatagta gctcccaaag ttgtttcacc tcatctttta
     3121 aacttgcaat aatctgaatt gagtgaatta aattccgatc aactttttgg gaatactctt
     3181 ctttcgtacc cggtctagtt tgcttttcta tccaatattc gaaatattct ttttctactt
     3241 ctgataattt aaaaaaagag ggggcactcc gattggactc caaaaaaatg tcatctggat
     3301 aactaatcat caactttttt gctatgctat tcgcaagttc atctttaaaa atgttgtaac
     3361 ggctagcatc aaaactaaaa tgtaggctct tttctttttt atcttcagat tcttctctaa
     3421 aatatttagc aatgatattt aatgccttta ccgcttgatt caaattgtta ccaatttgat
     3481 ttaactgttt ggttaaaact accctatcat cttcagctaa caacggcggt tcatatttga
     3541 gtccctttaa ccgctcacgg caaacgtctg ctctagaaat tcccctttgt tttgcaatca
     3601 atgtcagttc aagataagtc tttttatcga cacgaaaatt taaggcctca ctatgtttgc
     3661 gatttttttc gtacattttt tgtttatcat ccattgatta tcccctcaca tttttttcta
     3721 gagagcaaca tttgaaattg ctctctattt catttttcat ctttaattct tcttgaatca
     3781 tcagttcaat ataattagtg accgtgattt tttcatttgt tgcgttcttt actgattcac
     3841 ataattcgtc aagttctaag aaatcatgcg tactaatctt tagaattaat tgcatgacaa
     3901 tccccccctt ttatttctta ataaattatc gaaaagtgga ttaggatcat taagtgtatc
     3961 tctgaataac tcattgtctt cataagtgaa tcttcgtctt gattttgatc ccttatcatt
     4021 ttcacggatt tcactatcaa taatcactgt ttcatgattt gaatcaaatt ttttcgctga
     4081 ctttctgtct tcaacgatat tgattttttg tgttttttct ttcatttctc cactatcttt
     4141 ttgaatgttc tcccgaacat ctactgtttt gaatccttga ctacttgtag aactttgtac
     4201 attttctcgg acatctactg tttttggttg acttgcactg ctaccttgca cattctctcg
     4261 gacatccact gatttaaacc cttgactact tgtagaattt tgtacatttt ctcgaacatc
     4321 tactgttttt ggttgacttg tactgctact ttgcagattt tctcgaacat caattgtctt
     4381 agtaccttga gcatttgaag aactttgtaa attctctctt acatcaacat tccgtccaac
     4441 atgaccattc agtgaacctt gaatattttc tcggacatct actgatcggc caccatgact
     4501 acttgtagaa ttttgtggat tttctttgac taatttttct aatcctgtat ttgaattttt
     4561 agcttcttga attctttctt tggtcaacgc ttcttttccg tcaatattag cgcctgtccg
     4621 cccttctaca cgtttcctta acattatttc ctcgcgattc attgcttcag gcgtgtattt
     4681 cgcttcatga cgcttctgat taattaattc ttcagcagac ttagcttgac cgtgcatagc
     4741 atttttacgt tcttcaatat cttgttggac tttttgctga attgcgcttg caggattatt
     4801 attcgattca gcattatttt tcattgcttc acgcatacgt tcagaactag acataattct
     4861 atcggcattt tcaactttag caccatcttt tctatctgaa agacgtgttg gcacggaatc
     4921 agcatatttt ccagtttcat cttctttatt tttagctaac ataggtttgc tatttttatt
     4981 aatagcggac actgtaccat catctaaacc ttctttaaac ttattcttgg tatcattagc
     5041 tatatcacgc atactcttaa atggttttgt tgctctttca ctagccattg tagctccatc
     5101 tgaagctaaa ccggataatc cacgttcatg ggcatatccc aaagctcttc cagttttgcc
     5161 agcttttttt gatagagttt cgccgaaatt cttttctggt tttcgatctt ctccttctcc
     5221 gcttccttta gcacgattaa atccatttga tccttttcta aacagcattg cgcccattcc
     5281 aaaagcagaa gcaagttgcc catagccttc tttgagtcca atatcaacac caaagtatct
     5341 catgactgtt ccactgcctt tgattaaaac aaaaacggca cagatataag caattgtttt
     5401 tataaaaata tttgttgaga taccttgtcc tgagttcaga aaattgataa acatagcaaa
     5461 cattgataac ccaaatcctt gaaacccaac agttaagtaa cattgtagaa tatctgatag
     5521 aacaactttt gaacgctgtc ctgtctcaat atctgttgca aaaacaagaa cacctaacac
     5581 acgtttaaat gcaagttcta gtattgctgt aatgatcaca aacgcgctga acacataggc
     5641 gattgctaac gctgtcaacc caattgaaat cccccataga tttgcttggt atcggtaata
     5701 gcctgatttc aagctatcag aaaatgttga taagaagttg tcagaaaact ttgtagcaac
     5761 aaattcatta ttagaatttt caactaattc ataacgaaga ttgtccgcaa ttggattttc
     5821 tttttccaat ttatcaatca ctttatccgt taacacttgt gtgagatccg tctgttgaaa
     5881 attttttcgt gttaaattat ttcgatcctc cgttttatca atgcttgagt actgatctgt
     5941 tttattaata tatgctaaat ctgttactcc ttgttttatc aatgaccaag cgactccgtc
     6001 atctgaattt gtaatcgtag tagagtcctt ataaaatgtt ttagcaaatt gaataccact
     6061 agaaatcatg gttggcatta aaagtattaa tgctatagac atcactacgt tcattccaac
     6121 cgattttaaa tccactgttc cttttccagt aatcattttg taaccaacaa acatcaatga
     6181 aaggatcatt aatccaatga caattgtatt tacggctgat tgataaacat tatttagccc
     6241 tgtactttca atgaaattga acaaatccag cacatctgga atcatatttt gaatcgaatc
     6301 tgtcacagta aacatgcctt ttaccacagc ccatccgagc caaatcccga actgactaag
     6361 gaaatctcca ttgtactttt ttaggtaagg tctataaaga gaattattca aaaactctgt
     6421 ttgacttttt gtgtcatcaa accaattgaa aatactcgca tgagcaatat tacttgtaaa
     6481 aataatcata gctatcagaa caagaaaatt aacaaccaac caatttattt ttttattggc
     6541 aatctttttt tcaattattt tcatcgttac ctcccttagc ccattttctg aggctctcag
     6601 agagcttctg agccattttt tgattaatta tgacatgagt tacacaatta tcattttcag
     6661 ctcttaaatc gagaactata gtgttgaagc aaatagtctc gattaattcg agactatctg
     6721 tattttgatc tagacaccaa acttgatcta ttaaacgatt tttaatcaaa ataacccctc
     6781 ctatattcaa agttctcaaa tgaagtggag atacccctcc atttcatttg actcaattct
     6841 attcttattg cttatctatt ccttcgctga tttgcaattc aattagttct aacgctttat
     6901 tttttagaga agcaaagata taatcgtctt tttgtttgat acgatgatct gtttttgctc
     6961 ttcgtatcaa gtcacgtaaa gtcattgata gctgttctct aacatgatct acaaaatact
     7021 tgttattaca aatttcatag ataattttca gttgaatttt ttgttctttt tcagcagatc
     7081 taatcgcata tttgaatttt ttgtaccagt tgtcgaattg acgataatca ctattgctag
     7141 ccagttttaa gcaattcaca atactttctc cccatatttg tttaagaaga ttttcttcaa
     7201 taaatgtttc gatcaattct tcatctaatt tattattttt agttgaaagt gattcaagaa
     7261 gatcatcatt atgtgattct ttaatatctt tactatcttt ataagactta tataattcta
     7321 gttcattttt tgaactatca gcaaaattgt ttttgtctct tgttttcatt gatgtgtcgc
     7381 atagttcaaa ttttgaatta tcaacagaat attgatttgt tccatagttc aaattttgaa
     7441 ctatcaagtt tttttgtcta ttttcttgat gggttatctt attaatttta taaacatcat
     7501 ctttgcacag aacaggcttt aacaaataat aaaaatttgg gaacatttgc attttacttt
     7561 tattgaagcc attttttctt ttcacaagaa gtttaacttt ttgaagttca tctagtgctg
     7621 ataagattgt attttttgac attcccgaaa tttctacgag atttttgatt tcaaatatca
     7681 aaaaaatttt ttgattctca tcatacaagt tatttttcaa tgaaagtcta tttctatctt
     7741 ttagtaacat ataaactaac ttagaactta gtttcatttt cttatatttt tcatttacgt
     7801 ttaaaaaaat aggatattga tagtataatt ctgcatatat atcagaatta gaatagcctt
     7861 gcttttcaac taagctttca acttcttttt cattcattgt cacacctgct tctgatttta
     7921 tttgctataa tagattcaaa taaagttttc tcagaacttt attattgagt gttcccccga
     7981 tctgcaaact gacgggaaca ctctttttaa ttttttctac ttcatcaaat ttaaaaaacg
     8041 aggtgttttt taaatttgat gactcaatat ccattttttg cattcttctt ttgaaaacaa
     8101 ctccattttt tctaataaaa taactggcaa tcccattctt ttaaatttca aaaaagttgt
     8161 atatgataca ttcaaatatt tagccatctc ttttcctttt agaaatggtc tttctaatcc
     8221 ggtatcaatt cttgcttgat caatagcctc ttttgtcatt tcaaaaacat aatttttcaa
     8281 ttgattcgtt tgttgtttat ctaacattac tgtaattcct gcatccatta tttttctcct
     8341 ctcattttct atttcttcaa tcagccaact cgccaagttg tatttattta gattttcaaa
     8401 tcattaagta accaatttac caacttttga taagtagatg ctctaatact ttctttgctc
     8461 ccattttcga ttttgacata tgttttccga tttataccta tcaattttgc tgcatcgttt
     8521 ttagtaagta taagatcggc tctatgtctt cttaagcttc taatgaattg atcattaaga
     8581 gttatcattc agcgcctcct ttcaaattat tcactttgtg gtttttatct taataagcac
     8641 attttaaacc acaaaacgag taatatcaat taaaatatta ctcaatttgt ggttttcatg
     8701 ctataatagt ttggaattta ctataggggg cgttactttg aatagaataa aattttatat
     8761 tgattccagt aaaaagacca ttaaacaaat tagtacagaa actggtatta actatacaac
     8821 tcttacgaac tattaccgtg gtgagcgaaa tcctagaaat actgaaacat ggaatatcct
     8881 tgctgattat ttccatgttc ctgtaagtta tttgatggga ttagacgaaa caaattccat
     8941 agaacaacct aatcttgata gaataaaaac tgctcgttta gaaaaaaagg acaaaatagt
     9001 caagaatatt gccagtcttg actcagatta ttttactgaa ttatctaatc tatacttttc
     9061 catgacttct ttacttgaag tcaaacttca agaagatgac tccgactttc tttttttaaa
     9121 aagtattcta gaggactcct ttgaatacac gattctattt gccaaacaaa agaagtttat
     9181 taataaagct ttaaacttaa atatcgatga aagaaaagag ttagaatctg agttatttgg
     9241 caacttaacc caagtacagg ttaacaatct aaaaagagag ataacagctc gattaatatc
     9301 aaaacttcaa taaaactaat tattcaatca gccaactcgc caagttatca gattggagag
     9361 attagttatg tcaatacaaa agtacacaac aaaaagcggt gcacgatata gtgtccgctt
     9421 gtatgttcgt aaagatgaaa atggaaagca agaatactat gtaaaaaaag ggtttaaaac
     9481 tgaaaaagaa gccaagttac acgaagcaag aaaaaaggtc gagattgaag ataccggcta
     9541 tcataagcct tctaatgact tgtttataac agtgtatgaa gaatggttgc cttcttatag
     9601 gaatcgtgta caagaaacga catatcaacg tacaaaagac cttttccgct tgcatatact
     9661 accaaaattc gggaataagt ccatttctaa gattactcct gttcactgtc agaatgcagt
     9721 caatgaatgg gctttaaaat tcaagaatat caaacagctt aagtcttaca gctctcaaat
     9781 atttgagtat gccatttttg cagagctatt acaccgaaat cctatggcaa atacaaatct
     9841 accaaagcgg gaaaagaaag aaaatgaaaa ttacttttca ttagaagaac taaaagcttt
     9901 ttgggatatt ctcaataaag aagagccttt aaaacatatt ttaatcttcc agcttttgat
     9961 tactactggt atacgtaaag gagagctagc tgctcttcat tggtctgaca tttattttga
    10021 agaacagcta atgtatgtta gaaagagcta tgcaactatt cgaaatgaag agaagaatgc
    10081 aagaagaaaa actgtcagga ttcaaaaaaa tacaaaaaat atatcttccg aacgaatatt
    10141 accaattgat gcacaaacta ttgaaatgtt aaaaatctgg aaaaaagaac aagctcgaga
    10201 gcttttgcag tttggcataa atacaaatac aaaaaatcaa cttatcttta cctatgtaaa
    10261 tgcagacggt gacattaatc aacctttgca tgcggactat tcaaataata tattgaaacg
    10321 tttagagaag aaatataaat ttaagcacgt tactattcat ggattccggc acactcacgc
    10381 tactcttcta ctagaaggtg gagcaagtat caaagaaaca caagatcgat tgggtcataa
    10441 aaatgctgaa actaccctta acacttattc tcatgttact gaaaaagctc aacgaaatgc
    10501 gttagaaaaa ttcattgctt acactggttt ataatattgt cattaccttt ctcattacca
    10561 gaacgaaaaa aagacacctt ctcgcaatga gaaagtgtct gaaatcgttg gtataacaac
    10621 gattaacgtt ttgaaaactg tgaagcttta cgtgctttct taagacctgg ttttttcttc
    10681 gtatcattga ataagtttga aaaaccttga tttataaagg ttttcccgta aatatatttt
    10741 attatatttg attaaatttg aaatgtttgt gttctaaaat gtgttctaat ttaaaggcag
    10801 tatatttcgt attttagatt aaatttttag gctcattcat tctcaaatcc attctattca
    10861 gtcaataaaa attttaaaaa gactttataa acaaagatgt tcaagcgagc atcttatttt
    10921 tttgtgctta atttgaaagg agaacatttc atgtataaaa aacaaaaaaa gaaattatgt
    10981 gtattaacta ttttgagttt ggctgttcaa gcaattgttg gagcaattgc tcctacgatt
    11041 acttttgctg atgaaattac ccatccacaa acggtaaccg tagaactaga tttagcacat
    11101 caatatgctg ttgaaggaac ttttagtgat ggtcgtccaa tgtcagaagt cactgttccg
    11161 cattatgcag tgtacaacgg ctttaaacaa gatattttct gtattgaacc aggagtcccg
    11221 atttacaatg agttcactcc tggctatgag aaaaacccgt taccagatat gtccgataaa
    11281 gccaaattag tttccgtttt atggaaaaaa gtaggtacag atgcagatac tcatattgtg
    11341 gcacagaaga tgatctggca agaagttaat gggtataccc ttcactcaat aaaacgatca
    11401 gatggtagtg ccgtaaatat cgcagccatt gaggcaaaaa taaatcaagc cattgacgat
    11461 tatcagaaga aaccaacctt ccataatagt acggctaaaa cagtattagg gcaatcgact
    11521 actgtgacgg atacgaataa tctgaatttg tcagagttcg atgaggttgt ggaaaatgcc
    11581 gcaaacattg attatcgtgt gaatggtaat cagttgataa tcaccccaaa tgccaattca
    11641 aaagaaagtg gtgtgctgac gcttaagaaa tctgctggta ccggaacacc tgtcgcctat
    11701 aaaaaggctg gccaacagac tttaatggcc ggggcgattg ataaacctaa tacctacaca
    11761 atcaaaattg atgtggaaac ggagggttct ttaaagatca aaaaagtcga taaagaatcg
    11821 ggtgatgttg taccaggaac ggttttccat ttagactttg gaaaaacttt acctgcaaaa
    11881 gacgtgacta ctgacaaaga aggcattgct acattggatg agattcctca tggtacaaaa
    11941 gtaaccatta ccgaaaaatc agtaccggcg ccttatacga ttgataccac ccccatgact
    12001 accaccatta aagcaggcga aaccatttac gtgacttcaa aaaacgcacg ggaaaaaggg
    12061 caaatcattc tggataaaag cggagttgaa acagggagtg atctttggaa tgacaattat
    12121 tccttagctg gtaatacgtt tgccattcgc aaagacagtc caaccggtga aatcgttcaa
    12181 gaaatgacca cggatgaaaa cggtcatgcg gaaacaccaa aagagattgc taatgcgttg
    12241 gaattgggaa cctattatgt gaccgaaact aaagctagtc atgggttcgt gaatacgttc
    12301 aaacctgtaa aagtcgaatt gaagtatgcc aatcaaaccg tagcccttgt taccagtaac
    12361 gtaaaagggc aaaatcaaga agtcactggc gaaaccactt tgacgaaaga agacaaagat
    12421 actggggata aagcacaagg taaggcagtc tttgagggtg ctgaatacac cttgtttact
    12481 gctaaggatg gaaaagctgt taaatggagt gaggctttta aaccagagtt agcgaaggga
    12541 acgaaaggtt ctgatgaaac ggtcactttg actttagacg aaaagaacca agttgccgtt
    12601 aaacatttag ctatcaacga gtattattgg caagaaacaa aagcgcccga aggatatagc
    12661 cttgatgaaa caaagtatcc tgtatccatc aaaaaggtgg atgatagcga aaaaaatgcc
    12721 gtgattaccc gaaatgttac ggcaaaagaa caagtgattc gctttggctt tgatttcttt
    12781 aaatttgctg gatcagctgc gggcactacc gaaactggct tcaatgatct gacctttaaa
    12841 gtgtcgccat tggaagggac caatgaaatc acaggtgccg aagatgaagc gaccacagct
    12901 tataacgagc aattagggtt tgatggttat ggcaagtttg aaaatcttcc ttatggggat
    12961 tatttacttg aagaagtaga agccccagaa ggttttcaaa agattacgcc attagaaatc
    13021 cgttctactt ttaaggaaaa caaagaagac tttgtgaaga gtgagtatgt ctttaccatt
    13081 accgaacaag accaaaaaca accaattaaa acggtgaccg ttccttacga gaagctgacg
    13141 aacaaagcat tttctgttag tttgaaccgt ttaatgctct atgatttgcc tgaggaagaa
    13201 gatagtttaa cttctcttgc gacttggaaa gacggaaaca aagaattaac ttctctggat
    13261 tctaccgagc tagttgataa attgagttac aatctacatg aaatcaaaga agactggtat
    13321 gtggtagcgc aagccattga tgtggatgcg acaaaagctg cccaagaaaa agatgaaaaa
    13381 gccaaaccag tggtgattgc agaaacaagc gcaacgttgg cgaacaaaga gaaaacagga
    13441 acttggaaaa ttcagcataa attaaccgcc gaacaagttt taaataaaac tattgtctta
    13501 ttcaactatg tgtatgaaaa taaggaagct tttgaagcag gcgataagcc agtagcgaag
    13561 gatgttagct tgaataatca agcccaaact gttaattgta cggtggaacg tcatgtttct
    13621 atccaaacaa aggcccacct agaaaacggt tctcagacct ttactcatgg tgatgtggtg
    13681 gatatgtttg atgatgtgtc gattactcat gatgtactgg atggctcaaa agaagctttc
    13741 gaaacaattc tgtatgcttt attaccggat ggtacaaaca aagaaatttg gaaatctggc
    13801 aagattgatt atgaagtaaa tgataaagaa ttcaccaaaa ctgtgcttgc gaaaaaagta
    13861 gataccggaa aatatccaga aggaaccaag tttacttttg cggaaatcaa ttacgataaa
    13921 gatgggaata tcaatggaaa acacaatgaa gatttgaaag aaaaatctca aaccttaaca
    13981 ccaaaagaag ttccaaccat actaagtacg ccgaaacaac cggaaacacc aactgttcca
    14041 agtggctctc aagaatctag tcccacagtg aagaccttcc ctcaaaccgg ggagaaaaat
    14101 tccaatgttt tactgttcat tggttttact ttgatttttg cgacggcggg ctattatttc
    14161 tggaatcgcc ggaactaagg tgatgagatg atacaagtaa atcctaagaa ccaacgtgcg
    14221 cgaccgcctc ctaaaaaagt agtcgcgcta tttttgtatc caaaactaac aatgaaaaga
    14281 ggaaaagaag atggaattga aatttgtcgt gccagatatg gctgaaacct ttggaaagtt
    14341 aagttatgcc ggtgaaggag aaattataac agaaggatat ggacggaata ctacggtgat
    14401 tggtcgcagt tatcatttgt attccagtaa gcaacgggcc gatgatattg aggtggtagt
    14461 agctgcggaa gccggtgaaa aggattttga tcaagaccaa ccgctaaaag ccgtgaatcc
    14521 ccatttggtt gccaaaggct atgagattga gaatcgtggg tttactgatt acgtgttgta
    14581 tgttgatgat ttagtgaaag cataggagga aaagaagatg agattaacag aaggtattgt
    14641 cgtagattca ggtttaacat ttgggaagtt gcgtttttcc gcattacgcc gagaagtacg
    14701 gaagcaaaat gaggatggaa caattggtaa tgaggtaaaa gaacgaacct ataatttaaa
    14761 atcctctgca caagggcgaa tgattcaagt tagtatccca gctaatgtac ccttacgcga
    14821 gtttgcttat gatgcagagg tagagttggt caatccaatc gtggataccg ttgccaatta
    14881 tgtttttcga gaaggaacta ccgttaattg gttcattaag gcggatgatt tagtcttgaa
    14941 gcggcagccg aatcaaggaa atcctacgaa ccaaaatgaa agaaagaaat aggtgaagat
    15001 tatggaaatt aatgttgaac atattttaga ttgtctcgat caatatggaa aaggcgagct
    15061 gactgaggaa caactcgtta aagcattaac ctctgatgaa aaaatgtttc tgattataca
    15121 tcaaggttta cttggagaaa atagcgacag tgaagaagac tctgatgtac tagactggtt
    15181 aggagaagaa gagtctttct ttatagttgt cgaagtaaat gaaaacttat gtcggcaggc
    15241 agaatccatt ttggaagaaa ttggtgtgga gatgccggat gctattgaag gctttttaaa
    15301 tcaattggtt gaaacgaaac aactcccctc ctcgtagcag taaatgacta gcataacttt
    15361 ttgaaattgc ctaatgaaat cctattgggc tttttcgatt ggaggtggaa accatcaaaa
    15421 tgtacaaagg acatcgcata cgcgcaggag atcagcactt ggtttatcac tttgttcttg
    15481 gctggctact cgctctgttc atcggttgga tgagcgtctt ttattttcaa gagtttagac
    15541 aatttgatat ttctaagcta tcactttcta ctattgaaat cgtttggtct ataaaagatt
    15601 tagtatgtct gcttggaagt ctcgcttttt caggagctat gatattgctt tatattcact
    15661 tttttcctga tcattggcga agcttgtggc atcgacaaaa gctagctcgg atgattctag
    15721 agaaccattg gtatgaagtg aaacaaactc aaagtgaagg ctttttcaaa gatttgaata
    15781 gtagccgaac cagagagact atcagttact tccccaaaat ctattatcga atgaaagatg
    15841 gattactgtc tattcgcgtt caaatttcac ttgggaaata ccaagatcag cttttaaaat
    15901 tggaaaagaa gttagaaagc ggactgtatt gtgagttagt agaaaaggaa ctcaaagact
    15961 cctatgtgga gtatacttta ctgtatgata tgatcgccaa tcgaattggg atagacgaag
    16021 tagtggcaga aaatgggact ctgcgattga tgaaaaatca agtatgggct tatgattctt
    16081 taccccatat gttaatcgct ggtggcacag gtggagggaa gacctatttc ctcctcacca
    16141 ttatcgaagc actattgaag tcagatgcag aattgtttat cctcgatccc aaaaatgcag
    16201 atttagctga tttaggtacg gtgatgcctc atgtttattc acaaaaggaa gaaatttctg
    16261 cttgtgtgga agatttctat gaacgtatga tggctcgtag caaggcaatg aaagaaatgt
    16321 ctaactacaa aacaggagag aattatgcct atcttggact tccacccaac tttttaatct
    16381 ttgatgaata cgtggcttat atgggtgcga atcgttttcc tacaagcatc gaatagatgt
    16441 gaaatggaag cctattgaga ttatcaatag tgacaactaa tgttttgaga gatggaatga
    16501 aagccttcaa gttgagctga aacatccccg ctaatactcc tacatgctct aatcaatgaa
    16561 gtagattggt tttggtatga agctaggtga agtcgtctga aatctgccta agtgcttgag
    16621 cataaggctg actatagggc gggcggctga aaaagataac tatggtaaga atgtctgaaa
    16681 atgactgacg aatctgcgaa tgtacgggtc taaaaggctg atcttattga aagataggaa
    16741 catacggacg tatggtgaga taccgacaag taaggttcca tgatatgaaa atcgggatag
    16801 ctaacgaaga agctataatt tcacaggctc atagtagata cctaaggtta tacatgatag
    16861 ctaaaaacat tggaacgatg taagcagaaa actatcaatt aaatgactac ttctagatag
    16921 gtgcatataa gtaataacga aattgctttg tttctgtgaa agtaagggca cagtaccgat
    16981 gaagcgtcta acaaatgtgg agggatagcc ctaagtctat ttaataacaa tgaatgttga
    17041 aacagatgaa gttcaaggat ctggtaagaa cgtgggaaaa tccgttatgg aggtgccacg
    17101 cttgaacaca aaaatacgtt actgggaata ttatgatcta caagaaacat tcgatcagct
    17161 atttactcaa agtagaaacg ggaaaaagtt ttatcaatta tatgagttaa tcatttctga
    17221 aaataatatt cttttagcat accgtactat caaggcaaac aaggggtctt cgacaccagg
    17281 aacggattcc ttcacaattg ataactataa ggaaatgaac caagcagagt ttatccatct
    17341 tattctcagt catttagaaa attacaaacc aaaatccata aagcgagtaa tgatacctaa
    17401 acccaatggt gagaaacgcc cattaggaat tccatgcatg attgatcgaa tgatccaaca
    17461 gatgttcaag cagatactgg agccaatatg tgaagctaag ttttatgaac atagctacgg
    17521 tttcagacca ttgagaagtg caaagcatgc tctaggtcgc attatgtatc tcataaacat
    17581 cagtaaaatg cactatgcag tagacattga tatcaaaggt ttctttgata atgtaaacca
    17641 ccgtttactg ataaaacaat tatggaatat aggaatttgt gacaaacaag tcttagctat
    17701 tctttcaaaa tctctgaaat cacccattca aggagaaggt atcccgagca aaggaacgat
    17761 ccaaggaggt atcatttctc cactattatc taatgttgtt ctaaacgact tagaccattg
    17821 ggtctcaaag cagtggcata cctttgaaac aaagtatccc tatactaaag gttacaataa
    17881 atttcgtgct ctaagagata caaatctaaa gcaaggctat attgtcaggt acgcagatga
    17941 ctttaaaatc atgactaatg attatccgac agcattaaaa tggttccacg ctgtcaagct
    18001 ttacctaaaa gacagactta aattagatat ttccaatgag aagtctaaaa tcgtcaattt
    18061 gcgtaaatgt aagtcggaat ttttaggatt cgctatttgc gtgaaacaaa aagggaaaaa
    18121 atgggtttgt aattcacgta tttctaacaa aaaaaaggat cagattaaag aagagattaa
    18181 acaaagaatc aaagatattc aaaagagtcc tacagcacaa aatgctctcc tgtttaatgc
    18241 tctcgtgctc ggtgttcata attatttcag gtatgccact catattaatt tagatttgaa
    18301 taggatgaac tacgttcttt cattcactac ttacaaccga ttatcaaatt gtagtacaag
    18361 atgttacccc aacaaagctt ccccaactta caaaaagttt tactcaacaa cgatgaaaac
    18421 gtataaagta gctggagtct atttgtaccc tctttgcgac gtatctacaa aaacaattta
    18481 cggatttaat acggaggata caccgtttac tccgtttggt cgtcaaagat tggagcacaa
    18541 aagcctacag tctcttgtgt tccaagaatt aagaaaattg atggaatcga aaataccgaa
    18601 tagaacggtt gagtatttag atagtagaat atctcgttac tcaatgaaat caggcaagtg
    18661 tgagattaca aaacaatttt tgccagcaaa agccgttcac tgtcatcact atttgccaaa
    18721 aagtcttggt ggagacgaca aattcgataa cttgagaatt attcataagg atatccatct
    18781 tctgatccat acaacaaata aaatgataat cgatcactac gtgcatgaac tgaaactggt
    18841 gccagagcaa atagcaaaaa tcaaccttta tcgaaagatg tgtaatctgc aaaacattca
    18901 atagaaaata aatagatgga acgccgtatg aggtgaaagt ctcacgtacg gtgtggagcg
    18961 ggggaaaaga tggagattat atcaaattct tacctatcgc tatagatgtt aacgacgaaa
    19021 gaaagtgcgg tgattttgaa taagctcaaa caaatcgtga tgttgggtcg tcaatctggt
    19081 ttctttctga ttttggcttg ccaaaggccg gatgcgaaat atttaggaga cggaatccgc
    19141 gatcaattca actttcgcgt ggctttgggt cgtatgagtg aactcggata ttccatgatg
    19201 tttggggagg tcgaaaaaaa cttctttatg aagcacatca aaggtcgagg ttatgtggat
    19261 acaggtggca gtgtgattag tgagttttat acgccacttg taccaaaagg gtatgatttc
    19321 ttagattcaa ttagtaaatt agtaaattag aaaagatgaa tgattgagtg atcttcaata
    19381 ctgactttat acttcaagta acgtataata cttttatata gtaggaagaa aggggataat
    19441 taatatggaa agtaatgatt cttatttaga gtatgcaaaa gcaaataagg ataagtttat
    19501 ttcttatatt atcaaaggga aatcccccga agttggacga gacgcagttt ttatggcagg
    19561 gagtcctgga gctggaaaat cagaggttgc cattggatta gctgagaatt atgataacca
    19621 tgtgattatt gatgcggatt actttcgcac ccagtttcct gattataatg gaaaaaaact
    19681 ctagtctctt tcaaaaagca tcttcttggt tggtagagca ggcatttaga tatgtcttag
    19741 atcatggcta ttcttttatt ctggatgcaa cttttgcaat attaagtgct gaaaaaaata
    19801 tctcgcgggc gttgaaaaaa cattttcgag tgacgatttt ctacgtttat caagacccta
    19861 aaatcgcttg gaaatttaca caagaacgtg aaattgcaga gggacgtcat gtgccgaaaa
    19921 aggtatttat taacgctttt ttcaaatcaa gagagaacat tgcaaaagta aagagtaaac
    19981 atccagatgt attgcttcat atcataataa aagattatac gaataatatt tccgaagttc
    20041 attatgctgc ggacaatcta gaattatttt taccactagg gtatagtagg aaagatttgg
    20101 aggttcaatt acatgactga taaagaacaa gtaacgaaaa ttgtaaagaa atacaataag
    20161 agcattgcgg atttatcgga aaatgctact gcaaaagagt tcaaaacggt gattaaatat
    20221 gtagccgatc aggccaatga aaaacaacgg aaattagttg gattaaataa aaaatagtag
    20281 gacaaattaa taatgtatga gccaagagca aaatgttctt ggcttttttc tttgcaatga
    20341 atgaggtaat gtatgagatt tttagattta ttcgccggta ttggtggctt tcgtttaggt
    20401 atggaacagg cgagccatca ttgtatcggt ttttgtgaaa ttgataaatt tgctagacgt
    20461 agttataaag caattcatga tacaagtaag gaggtggaaa tgcatgacat cacaagtgta
    20521 tcagatgagt ttattcaatc cctcggacca gttgacatcc tttgcggcgg atttccgtgt
    20581 caagcttttt caattgcggg aaagcgacaa ggattttccg atactcgagg tactttattc
    20641 tttgaaatcg ctcggttcgc cgctcttctc cgacctaagt ttttattcct tgagaacgtc
    20701 cggggattgc tcaatcacga agggggggct acgttcgaga cgatcctccg aacgctggat
    20761 ggattggggt atgacgtgga gtggcaggtg cttaactcaa aggcctacat tccccaaagc
    20821 cgggagcgta tcttccttat cggacattct cgagacgcat gtaccgaaca agtatttcct
    20881 atcattggac cgtcttcaac atctgatcaa aacatcagaa atttggtaaa tatcaatcct
    20941 tccaatcgag gaatgggtgg acaagtctat ggttcagatg gcgtagcgcc aaccttaaca
    21001 ggtgatgaag gaatcaaaat tgcactgcca gcaagggatg gaatctctgt agcaggacta
    21061 ttaccgggaa agtttgaaca aggtaatcga gtttatgaag ttactggaac cgcccccacc
    21121 ttgtccacga aacaaggtgg tacaaaaatc atgattcgaa aaaatgaaac agaatatcaa
    21181 gaggtgaagc caggagacag tgtgaacctg gcttttccta attccacaag tcgccgaggt
    21241 cgtctgggaa aacagagtgt tcatacttta ctgacaggag accaacaagc gattgtcacg
    21301 gatcagtatc aaattcggaa gctaacacct agagagtgtt ggcgacttca gggctttccc
    21361 gattgggctt ttgatcgagc ttctcaagtc aattcagata gtcagttgta taagcaagcc
    21421 ggaaactctg taacagttcc ggtcattttt gatattgcca gaagattaaa ggaggtacaa
    21481 aagtgtgatt tatgatgagt tggttggaga aatttattgg gtgattgaaa agattcagtc
    21541 agacccagaa ttagaagaac aattgcgacg gttaaacttt gatattcgca agaatggtgt
    21601 caaagtcgct ggcgatccat atttaatgaa tgaggagacg gatgctcgaa ttgaaataaa
    21661 ccaagtaatt gcagaatttg agcggattgc ggaccaagca aaagaaccgg atattcgtca
    21721 atacttgtta gaaatgaaag cagagttgga agtaaatggt attacagatg agtaacctaa
    21781 accaacacaa ctgactgtta ggcgctgacc gcggaggatt cgcgaagcag aaatcctccg
    21841 tggtgctgtg cctgttcatg gacggcgtta gccggccatg atgtctcacc ccccgtatct
    21901 aacagggggg tacaaaaaca caaaaaacaa gcaagcagcg attaagaatg gttgtcatga
    21961 cgaggatagt tagctgtttg aacaggtgtt aactcatttt gaaaagttaa caccttattt
    22021 ggaggtgaaa acttggtaca acagaactta gattatcgtt tactaaaaga tcggcgcaat
    22081 caatatggtg tttctcaaaa taaattggct actgcttgtg gattgagtcg tccctatttg
    22141 aatcaaatcg aaaatggtgg cgtaactaca tctacaaaaa ctatgagaaa aatttttgac
    22201 caactggaaa gtttcaatcc cgatttgcct ttgacgttac tgtttgatta tgtaaggatt
    22261 cgttttccga caacggatgt tcaaaaaatt gttcaagaga ttttgcattt gaaatttgac
    22321 tatatgcttc atgaagacta tgccttttat tcgtaccaag aacaatacat catgggtgat
    22381 attgtggtga tgctttctca tgaggaagag aaaggcgttc ttttagaatt aaaaggtcgt
    22441 ggttgtcggc agtttgaaac ttttttgctc gctcaaaagc gtagctggta cgactttttc
    22501 gatgattgct taaaagctgg aggcgtcatg aaacgcttgg atttggcaat caatgatcga
    22561 gttggcttat tggatattcc tgagttgacg aaaaaatgtc agaaggaaga atgtatctcc
    22621 ttattccgga cttttaagag ttaccgctcg ggtgaacttt tgaaagctga tgaaaaggat
    22681 ggaatgggaa atactttgta tatcggaagc cttaagagtg aggtttattt ttgtttatac
    22741 gaaaaagact atgaacaata tatcaaattg ggaattccgt tagacaagag cgaaacgaag
    22801 aatcgctttg aaattcgatt gaaaaatgac cgtgcctacc atgcaataca agacttgtta
    22861 aaaggtcgaa gtattgaggg taccacattt tccattatca accgttactt acggttcacg
    22921 gataaagttg aagggaaacg gcgaacaaac tggccgctaa atgaacgatg gggtcgcttt
    22981 atcgggcgaa atcgcaagga aattcaactg acttctgacc ccaaacctta tactatcgag
    23041 cgaacactga gctggctagg tcgacaggta gcacctacgt ggaagatggc taaggagtta
    23101 gatcggttaa atcagacgac ttatattctt gatatggtac agaatgctca gctatcggat
    23161 cggcataaaa agattttgga acaacaaagt atggcaatag aaaacttgat tatatgaaaa
    23221 gaggaagcag tatgcttggt attaccgtga tgtgcttaat tcatacaagt gcggctgcag
    23281 atcgagtaat ggaaaggaaa gtgataaaat gaatttcgga caaaattt
//
LOCUS       DAFEEZ010000044        23099 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000044
VERSION     DAFEEZ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.045"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            103..273
                     /locus_tag="LP245_001832"
     CDS             103..273
                     /locus_tag="LP245_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519752.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            493..1200
                     /locus_tag="LP245_001833"
     CDS             493..1200
                     /locus_tag="LP245_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1519753.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(1259..1903)
                     /locus_tag="LP245_001834"
     CDS             complement(1259..1903)
                     /locus_tag="LP245_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBL1519754.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            2030..2317
                     /locus_tag="LP245_001835"
     CDS             2030..2317
                     /locus_tag="LP245_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519755.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            2425..2745
                     /locus_tag="LP245_001836"
     CDS             2425..2745
                     /locus_tag="LP245_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1519756.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            2826..4139
                     /locus_tag="LP245_001837"
     CDS             2826..4139
                     /locus_tag="LP245_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBL1519757.1"
                     /translation="MNHFWGRRLLTRDIEAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            4136..4855
                     /locus_tag="LP245_001838"
     CDS             4136..4855
                     /locus_tag="LP245_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBL1519758.1"
                     /translation="MRCSCCSKDIFQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            4983..5534
                     /gene="raiA"
                     /locus_tag="LP245_001839"
     CDS             4983..5534
                     /gene="raiA"
                     /locus_tag="LP245_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBL1519759.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            5756..8290
                     /gene="secA"
                     /locus_tag="LP245_001840"
     CDS             5756..8290
                     /gene="secA"
                     /locus_tag="LP245_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBL1519760.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            8416..9517
                     /gene="prfB"
                     /locus_tag="LP245_001841"
     CDS             join(8416..8487,8489..9517)
                     /gene="prfB"
                     /locus_tag="LP245_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBL1519761.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            9622..10308
                     /gene="ftsE"
                     /locus_tag="LP245_001842"
     CDS             9622..10308
                     /gene="ftsE"
                     /locus_tag="LP245_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBL1519762.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            10292..11185
                     /locus_tag="LP245_001843"
     CDS             10292..11185
                     /locus_tag="LP245_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1519763.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIRPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            11337..12785
                     /gene="cls"
                     /locus_tag="LP245_001844"
     CDS             11337..12785
                     /gene="cls"
                     /locus_tag="LP245_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBL1519764.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            13122..13979
                     /locus_tag="LP245_001845"
     CDS             13122..13979
                     /locus_tag="LP245_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBL1519765.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            14094..15014
                     /gene="pstC"
                     /locus_tag="LP245_001846"
     CDS             14094..15014
                     /gene="pstC"
                     /locus_tag="LP245_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBL1519766.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            15014..15898
                     /gene="pstA"
                     /locus_tag="LP245_001847"
     CDS             15014..15898
                     /gene="pstA"
                     /locus_tag="LP245_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBL1519767.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVMKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            15913..16719
                     /gene="pstB"
                     /locus_tag="LP245_001848"
     CDS             15913..16719
                     /gene="pstB"
                     /locus_tag="LP245_001848"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBL1519768.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDIHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            16735..17493
                     /locus_tag="LP245_001849"
     CDS             16735..17493
                     /locus_tag="LP245_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBL1519769.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            17506..18183
                     /gene="phoU"
                     /locus_tag="LP245_001850"
     CDS             17506..18183
                     /gene="phoU"
                     /locus_tag="LP245_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBL1519770.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            18406..19437
                     /locus_tag="LP245_001851"
     CDS             18406..19437
                     /locus_tag="LP245_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBL1519771.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNSDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNKSILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            19434..20201
                     /locus_tag="LP245_001852"
     CDS             19434..20201
                     /locus_tag="LP245_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBL1519772.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALIVLPLTCVTTAYLFTKKKEQLKME"
     gene            20301..21869
                     /gene="liaX"
                     /locus_tag="LP245_001853"
     CDS             20301..21869
                     /gene="liaX"
                     /locus_tag="LP245_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBL1519773.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDKASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQALEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            22045..22353
                     /locus_tag="LP245_001854"
     CDS             22045..22353
                     /locus_tag="LP245_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBL1519774.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTKKRKEAEKIDDDEWSDF
                     "
     gene            22353..22703
                     /locus_tag="LP245_001855"
     CDS             22353..22703
                     /locus_tag="LP245_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBL1519775.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALFVAILM
                     SLVNVIVSEHNSRK"
     gene            22841..>23099
                     /locus_tag="LP245_001856"
     CDS             22841..>23099
                     /locus_tag="LP245_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1519776.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTL"
BASE COUNT         7609 a         3977 c         4971 g         6542 t
ORIGIN      
        1 gttagttcga gagctctttt ttttgctttg ctaccttgtt ccttgaagat tctgctgaat
       61 taagatagag ttaagttaac tacaagaatt ggagggatcc acatgaaatg gaaagaaaaa
      121 gtagacgaag cagctgaaaa gttatatgat ttggtcaaat cagaaaaata caatattgaa
      181 gtgaatattc cgaaaaaagg cggaaaagcg gtccaggtaa aatcaaaacg cccaacgaat
      241 catacaaaaa aatggatggc taaaaaccgc taataataac aaaagatcca taagtcggca
      301 ttttcatcga ttttagggtc ttttgttatt ttctaggttg aacatatcta aaaaattgtt
      361 tctgacaata ggagtaggga gaacgatgtg tgtctaaatc ctctgttgat ggatagaaac
      421 ctttatcttt ttcagttgtg aatcaggtat ataccagtta taatagaaga aacgaaagga
      481 cgggtgtacg ttatgtcgaa tcaattacct gtatatatac agattcatga ccaattaaaa
      541 aatgaaatcg aacagggtat atggaaagtc ggagaccgtc ttccttcaga aagagaatta
      601 gcagtgaaat tcaatgtcag ccgtatgacg ttgagacaag caattcaaaa cttggcagat
      661 gaaggaatct tagaaagaaa gatcggttcg ggtacgtatg ttgcgcgaga aaaagtacaa
      721 gaaaaaatgt ctggtgcaac aagttttaca gaaattatgg aatcacaaaa tcgagtaccg
      781 tctagtcgga caatctctta tttcttgact tcgccaagct caagtgaaat ggaaaaacta
      841 aacttgagta aagatgacac gatcttgcga atggaacgta ttcgtttcgc agatgatgtc
      901 cctatttgtt ttgaagttgc cagtgttcca caaaagctga tcgatggcta cagcaaagca
      961 gagattactg aatcgttgta tcgcacgcta gaagaaaaag gcgggaaaaa gatcggtcca
     1021 gcgaatcaaa cgattactgc tgtgttggct tctgagaaaa ttgctgacta tttagaggta
     1081 aaacgaggag atgcagttct tcgtttgcgc cagatttctt attttgaaga cggtacgccg
     1141 tttgagtatg tgcgtacgca atacgtagga aatcgttttg agttttattt ggaaaaataa
     1201 aaaacaggtg atccctgatt ccttattaga aataaaagag aatcagaatc acctgttttt
     1261 atatatgatc agttatcagt tgctcgtgat aagaaacaga accctcttca aattggactt
     1321 gtccgttcag cagctcaatg atggattctt taaagtggtc agcacttttt tcatctacag
     1381 cacagatgac gctaacttga tcagtatatt ggatttcttt tataaaaaaa tgttggagtt
     1441 caagataatt ctgtaatttt cctagttgcg gatacgtgat catcacagag atctcctgtt
     1501 gcaaggtacc ttctacgatt ccaatgtcag acaatgcttg agagaccgca tgagtgtatg
     1561 ctcgtattaa tccgcctgtg ccgagtttcg ttcctccaaa atatcgagtg actactgcag
     1621 ctacattgat cagttgattt tttttgagga cttccaacat cggtacgccc gccgttccac
     1681 ttggttctcc atcatcgctg cttcgctgga tttcattttt ttctccaatg atgaaggcgc
     1741 tgcagttatg gttcgctttc caatgttctt tttttatttc ttgaatgaaa ctttttgctt
     1801 ggtcctctga ttctattcgt ctaagagaac agataaagcg tgattttttg atctcaatct
     1861 cactttgtcc attttctttt attgtacgat agcgctcgat catcttgtca cctctttttt
     1921 tcattttctt tattcagtat aaataaagtt ctaggttgtt tcaacactgt aacggttgcg
     1981 caattgctgt agtatgcgat aataaagaca aaggcaggtg gatctgggga tgcaggaacg
     2041 aatgaaaaag tacgatgcaa ttacgcatta tttgaagaac aatggcggct ctcaagtaac
     2101 gttgaccttt acccaatttg acgaactgct gtttcccagt aacggacttc ccaaaacagc
     2161 aagggaaagt acagattggt gggcaaatga ttataaacac cctgaaaaag gtgcctatgg
     2221 ctggataaat gcaggctatg aagtagttgt catcaatttg gacaaagaat atgtcgtgtt
     2281 caataaatta gtgaaatcta gttggctatt tgattaaata aaccgcgttt agaaaacgtt
     2341 gacaaatttc tttcttttta tataatagag taacagacgc gaagaaaacg tttgcatagt
     2401 ttgttttaaa aaggagagaa aagtatggct aaaaaaacaa tcatgcttgt atgttcggct
     2461 ggtatgagca caagtttact agtaacaaaa atgcaaaaag ctgctgaagc aaaaggaatc
     2521 gactcggata ttttcgctgt gtccgcttct gacgcagata acaaccttgc aaataaagac
     2581 gtggatgtgt tgttattagg cccacaagtt cgctttatga aagctgattt tgagaaacgt
     2641 ctggaaccaa aaggcattcc tttagatgtc atcaatatgg ctgattatgg tatgatgaat
     2701 ggcgaaaaag tgttagatca agcaatcacg ctcataggtg aataaataga acagtataac
     2761 tatcgaacaa gcgatccaaa aaatagatcg cttgtttttt cgtatatttt tttagggcga
     2821 agaatatgaa tcatttttgg ggtagaaggc ttctgacgag agatattgaa gcaatagact
     2881 gtgaggaggt aaatttacca aattatgaga agatcgcagc agtggaacgt ttgggcaact
     2941 ggattctttg tcatcgctgt ggaatgagga cgtccgtcat tgatggacag cttgcagatt
     3001 acggttattt ttgtacacat tgtctatatt tagggcgatg cgacactcaa caagatttat
     3061 atttgtttga tcagcctgaa gcaaaacctc gagaagtcgt ctttttttgg acaggacagc
     3121 ttactgaaaa acaaacggaa atctcaaaga gaatactttg ccattcagaa aaaagacatc
     3181 atcttatttg ggctgtaaca ggtgcaggga aaacagagat gctttatcct attttagtgg
     3241 aaactttaaa agctggagga agagtagcga tttgtacacc gcgagtcgat gtttgtaatg
     3301 aattgttttt acgctatcgt tatgtttttc cagaagaaaa aatcacgttg ctccatggga
     3361 atacagcaac ggcttatacc tttacttctt ttgttatctg tacgattcat cagctatacc
     3421 gtttttatcg gtcctttgat ttaatagtga tcgatgagat cgatgcgttt ccttataacg
     3481 gggatgcagg attagctcat gctgtgcaaa cagcgattaa accagacgga cgattcatct
     3541 acttaagtgc cacacctgat aaaaagttac taaaggaaat caagcagacg tttgacatcc
     3601 acaaacttgc tttacgcttt catcggcgtt tgcttcctga acccgtcttg gttttcatga
     3661 ataattggcg acaaaaatgc aagaacaaga agaagataaa atctttggtg cggatcattc
     3721 atcaattaat taaagaaaac catatccttt tattttgtcc aagtatcacg atgatgcatc
     3781 gtttgaaagc cacacttcaa gaggctcttc cgagatatga gatcacagat gtttcttcaa
     3841 gagacaatca gcgggcggaa aaagtccaga aaatgcgaga agcaaaatat gatatactgt
     3901 taaccacgat gatccttgaa cgtggagtca catttgaaag aatatccgtt atcgttttag
     3961 gagcggatca tccggttttt actaaatctt ctttggtaca aatcgcagga agagccgatc
     4021 gtaaagggcc ttatacgaac agtcaagtat actttttcta tgaagaaaaa actgcagcta
     4081 ttcgaaaagc ttgtcaggaa atcaaagaaa tgaatgaaga agggaagaag atgctgtgag
     4141 gtgcagttgc tgcagtaaag atatcttcca aaatttaaca ttcagcgaga ttattggtgt
     4201 ttcgaaatac agattacctc agacttgttc agtttgtcgc gcacaatttc atttattgga
     4261 aacaagaggc tgttctggct gtcaaaaacc aatccatttc aatctagaga gtacgaaaaa
     4321 gaaagtaaag tctattcccg tttactgcag tgactgtcaa gaatggaaga agaaatatcc
     4381 gacctatgat tttcagcacc gtgccttttt tgtgtacgat gaaaatatga aggcctggct
     4441 caatcaatac aagtttatgg gagatatccg actagcaggc acctttgcat ataaatggac
     4501 gcagataaaa aaagaatacc cgacatacat ctattgtcca atacctttat ctgaaaaaag
     4561 gcgaacagaa agaggattca atcaagtaag cgagatgttg aaagcagcaa gaattccttt
     4621 tcagatgcta ctcaaaagag agaagcatct gctggctcaa gcaaaaaaca cgcgaaagga
     4681 aagattggag atgcctcaac cttttgaact tgcagtcacc ttttctaaga tacaaaataa
     4741 aaaaatattg attattgatg atgtctatac aacaggacag actcttttcc acgcagcaga
     4801 ttgtttgcag gtcgcacagc cgaaaatcat ccgaaccatt tctttggcga gatgaattag
     4861 atgtggaaat ttgatagcga tttaatttgc aaataaccta gagttcgata taatagaatt
     4921 aagaagaggg aaagagtggt ccttctcctt cttgattgtg gtagacgaaa ggggtaattt
     4981 ttatgtttag atataatgta cgcggcgaaa atatcgaagt aactgaagcg attcgcgact
     5041 acgttgagaa aaaagtaggc aaactagaac gctatttcag tgacgcaccc gatgcaacgg
     5101 cgcatgtgaa cttaaaagtt tatacagaaa aaacagcaaa agtggaagta acgatcccat
     5161 taccttatct tgtattacgt gccgaagaaa cttctccaga tttatacgca agtatcgatt
     5221 tggttgttga taaattggaa cgccaaatcc gcaaattcaa aacaaaaatt aatcgtaaat
     5281 cccgtgaaac gggcatgaat actgcagatg ctgctgcttt attcaatgaa gaggacgaaa
     5341 acgaaaatga ttctgaatta gatatcgtac gtacgaaacg cctttcattg aaaccaatgg
     5401 atagtgaaga agcagtctta caaatgaaca tgctgggaca taacttcttt atttttgaag
     5461 atgcagaaac aaatggtaca agtatcgttt accgccgtaa agatggaaaa tacggactga
     5521 ttgaaacaga ctgatcagcc ttacttaaat aacaacgaaa acttgcagca gctactgaca
     5581 gctgccgcaa gtttttttga gtttcctcct cttttagatg aaatatgaat aaattatgaa
     5641 gttcttactt taatacgctt aagatatttc aattatctat aactaatgat aaaatgaaaa
     5701 gtaaagtcta catagtctgg ataatacaca gaaggaaaag gagattacac aacgcatggc
     5761 caatttgatt cgttcactta tcgaaaacga taagaaagaa ctaaaacgtt tagatagcat
     5821 tgcaaaaaaa gttgaagcat acgctgacca aatggcagca ttaactgatg aacaattaca
     5881 ggcaaaaact gctgaattca agggcagata ccaaaaagga gaaacattag atcaattact
     5941 tccggaagct tttgcagtcg tccgagaagc agcaaaacgt gtattggggt tatatccata
     6001 ccacgtacaa ttgatgggtg gaatcgtgct tcacgatgga aatatccctg aaatgcgtac
     6061 tggtgaaggt aaaaccttga ccgcaacgat gccagtatat ctaaatgctc tgactggcga
     6121 aggggtacac gtagttaccg tcaatgaata tttagcaacc cgtgactcga cggaaatggg
     6181 cgaactttat aatttcttag gattaacagt ggggttgaat atcaactcaa aatcttcgga
     6241 tgaaaaacgc gaggcttata attgtgatat cacttatagt acgaataatg aattaggatt
     6301 tgactacttg agagacaata tggtcgttta ccgccatcaa atggtacaac gtccgctgaa
     6361 ttatgccatt gtcgatgaag ttgactcaat cttgattgat gaagcgagaa cgccgctgat
     6421 catttcaggg caagcagaaa aatccacagc tttatataca agagcagaca acttcgtgaa
     6481 acgtttgaaa gaagaagaag attataaaat cgatgtacaa tcaaaaacaa tcagtttaac
     6541 cgaagcaggg atcgaaaaag cagaagaaac attcggtttg gataacttat acgacattga
     6601 aaatactgca ttgacccatc acttggatca agcattgaga gccaactata tcatgctttt
     6661 agatatcgat tatgttgtcc aagacggaaa agtactgatt gttgaccagt tcactggtcg
     6721 gatcatggat ggacgccgtt attcagatgg acttcaccaa gcaatcgaag ctaaagaagg
     6781 cgtagagatc gaagacgaaa cgaaaaccat ggcgacgatc actttccaga actatttccg
     6841 tatgtacaag aaacttgcgg gaatgactgg tacagctaaa acagaagaag aagaattcag
     6901 agaaatttat aacatccaag tataccagat tccgacaaat cgtccggtta tccgtgatga
     6961 tcgtccagat ttactttacc caacattaca aagcaagttc cacgctgtcg tgcaagatat
     7021 caaagatcgc taccgcaaag gtcaacctgt gttagtcgga actgttgcgg ttgaaacatc
     7081 tgagttatta tcagatatgc tgaatcaaga acgtattcct catgaagtgc tgaatgcgaa
     7141 aaatcacttt aaagaagcag agatcatcat gaatgctggt caaaaaggtg ctgtgacgat
     7201 tgctaccaac atggctggtc ggggaacaga tatcaagtta ggacttgggg taagagaact
     7261 tggtggtcta gcagttatcg ggacagaacg acatgaatct cgtcgtatcg ataaccagct
     7321 tcgaggacgt gcaggacgtc aaggagaccc tggtatgtca caattctact tgtcattgga
     7381 agatgatttg atgaaacgat tcggttcaga acgaatcaaa gctttcttag atcggatgaa
     7441 gatcggtgag gaagatgctg ttatccaaag caagatgctg acgaaacaag tagaatctgc
     7501 acaaaaacgt gtagaaggaa ataactatga cacacgtaaa aacgtcttac aatacgatga
     7561 tgtgatgcgt gaacaacgtg aagtaatcta taaacagcga caagaagtaa tcatggaaga
     7621 aaaaagctta tccaagccac taatgaacat ggtcaaacgg acaatcagtc gtgtagtaga
     7681 tgcgcataca caattagaga aagaaaattg gaatttggaa agtatcatcg attttgccgg
     7741 cagtactctt gtccatgaag atagtattac tcttgcagat atcgaaggaa aaacatctca
     7801 ggagatcaaa gagtatctaa acgaacgagc acaagaagta tttaatacca aagcggctca
     7861 actaaatggt ccagagcaac tgttggaatt tgaaaaagtc gtgatcttgc gtgttgtgga
     7921 ctctaaatgg acagaccata ttgatgcaat ggatcaatta cgtcagtcaa tcggcttacg
     7981 tgcttatgga cagaacaatc cattagtcga atatcaaaca gaaggctata agatgtttga
     8041 agatatggta ggcgccatcg agtatgaagt cactcgaatc tttatgaaag ctgagatccg
     8101 tcaaaacgta cagcgtgaac aggtttctca aggaacagct tctcactcag aagacggaga
     8161 tgccaaagaa aatagtaata ctagcgcgaa aaaacagcca atccatgtga acaaggtcgg
     8221 aagaaatgat ccttgtcctt gtggaagcgg gaaaaaatat aagaactgtc atggaaaaaa
     8281 tgcaaactaa tttctgacag caggattggt gagacaaatt ctttttttaa gaattcgtct
     8341 caccttcttt ctgttatttg ctgattctgt tagactagat ataatgaaaa aagtatagtg
     8401 aaagaaggaa aaaacatgga aatatccgaa attcgaaatc tcctgacaga aatgcaggaa
     8461 aaggtcacaa gtttcaggag gtctctttga cttagatcag ctggaagaag acatcgcgga
     8521 agcagaagca aaaatggctg aacctggttt ttgggatgac agcgaagccg cacaaaaagt
     8581 gatcagcgaa aataacgcta ataaagaaac ctatgaccaa ttccattctc ttgccgaaga
     8641 actagaagaa atcgaattga tggtggagat gctgcaagaa gaacctgatg cagcaatgca
     8701 agaagaagca gaaacacgta tcaatgcatt agatgaaaaa atgaagacgt atgaattatc
     8761 tatgctgtta gacggacctt atgatcgaaa caatgcgatc gtcgaattgc atccaggggc
     8821 tggcggaacg gagtcccaag actggggcag catgctttta cgtatgtata cacgttgggc
     8881 agagcagcat ggctatcaag tagaaacact agattatcaa gcaggtgatg aagcagggat
     8941 caagagtgtg accctgctga ttaaaggaca taacgctttt ggttatctaa aatcagaaaa
     9001 aggtgttcat cgccttgtac ggatttcgcc ttttgactca gcgaaacgac gtcatacttc
     9061 tttttgttcg gtagatgtga tgccagagct tgatgaaacg atcgatatag aaatcaatcc
     9121 agatgatttg aaaatcgata cgtaccgagc aagtggtgca ggtggtcagc acatcaataa
     9181 aacagaatct gctgtacgga tcactcactt gcctacagga acagtagtag ctagtcaggc
     9241 acaacgctca caattgaaaa accgtgagca agcgatgggg atgttaaaag ctaagcttta
     9301 tcaattagaa gtggaaaaga aagaacaaga agcagctgca cttcgaggag aacaaaaaga
     9361 aatcggctgg ggttcacaga tccgttctta tgttttccat ccctattcta tggtaaaaga
     9421 ccatcggaca aacgtagaga caggaaatgt ccaagcagtt atggacggtg accttgattt
     9481 atttattgac ggctatttaa aaatgcatct acaataagaa ctcattgtta aattgaaata
     9541 aaattgtaag attttgcaag catgttgaaa cattgccatg ctataatagc taaagactga
     9601 aaaagatatg gagagaacgc catgattgaa atgaaggatg taatgaagaa gtactcaaat
     9661 ggtacgaccg ctatccgcaa tctctcgatt gtcatcgaac aaggagagtt tgtctatgtg
     9721 gttggtccgt ctggagccgg taaatctaca ttcatcaaat tgatgtatcg agaagaaaaa
     9781 gcttcaaaag gaactttgaa cgtcgcaggt catgatctaa tagcaatcaa aaaccgcgaa
     9841 gttccttatc tacgcagaga aatcggcgtg gtgttccaag actataaatt attaccaaga
     9901 aaaacagtat atgaaaatgt tgcgtacgct atgcaagtta tcggcagaaa acctcgagat
     9961 atcaaaaaac gagtaatgga agtgctggac cttgttggtt tgaaacacaa agttcgagtc
    10021 tttcctagcg aattatccgg tggggaacag caacgtgtct ctattgctcg ggcaatcgtg
    10081 aatacgccta aagtacttat cgcggatgaa ccgacaggaa atctggatcc agaaaactca
    10141 tgggaaatca tgaaattatt agatcggatc aatgcccaag gaactactgt cgtgatggct
    10201 acacataaca gtacgatcgt aaatacgatt cggcaccgag taattgctat cgaaaacggc
    10261 cgcattattc gagatcaagc ggaaggggaa tatggatacg atgattagaa cctttttccg
    10321 ccatttatta gaaagtatca agagtttgaa acgtaacggc tggatgacag ttgcttcagt
    10381 cagtgcggta acgatcacgt tgactttagt cggtgtattc atggcagtta tcatgaatgc
    10441 aactaaatta gctcaggata tagaaggaaa cgttgatgta tctgtattcg tagatatcgg
    10501 tacaaaagac gaagagatga aaaagctaga aaaagaattg aatgacttag atcatgttaa
    10561 aaaagttgaa ttttcaagca aagaacagga attgaaaaaa atccaaaacg aaatgggtga
    10621 ttcctggaaa ttgtttgaag gtgacaataa cccgttatat gatgtgtatg tagtaagtgc
    10681 tactgatcct tcttatacaa aacaagtagc agaagaagca gcagatttga agaatgtttc
    10741 tcgttctgat tacggtggag cttcctcaga tcggattttc caaatcgctg gtgcagttcg
    10801 gacatgggga ttagttgcag cggcattgct gctgttcgta gcgatgtttc tcatttcgaa
    10861 cacgattcgg atcacgattt tgtctagaca gcgtgaaatt caaatcatgc gtttagtcgg
    10921 tgcaaaaaat ggatatattc gctggccgtt tttccttgaa ggtggctgga tcggtctgat
    10981 cggtgcgatt cttccgattt tgatcatcac atttggttat gcatggtttt tccaattgat
    11041 caatccatca ttattacgtt cccattattc attgattcgt ccacaaaata tcgtttggaa
    11101 aatcaatctt ttaatggtcg gcattggtgt gatcattggt tcacttggct cgatcatttc
    11161 tatgagacgt tttttgaaat tctaatacca caatataaat aaaatgagaa agttggacag
    11221 tttcgttcca gctttctttt tttattggct aggagaatag aaggaagcgg cttttttccc
    11281 tttactttaa aaaacaactt gggtattctt aagttggtag aagaagaggt gaagccgtga
    11341 aaattatcgt tgacaatttt tttacgatcc ttttgattat gaatattttg ctttccttta
    11401 tcatcgtttt tcgagaaaga aaggaaactg ctcaaacatg ggcatggctg ctcgttttga
    11461 tgttcattcc agttgtagga tttattttat atattttttt aggaagaggg atttccaaag
    11521 agaaaatctt tgatttgaag atccaaggga aaatcggtaa gaacctggaa attgaagaag
    11581 acaaacaggc attgatgcga gggctttatc ctcatccgcc tactggacaa gtagatgtga
    11641 aacaattgat ctatatgctc acggtatttg aaagtacgct ctatacgact aaaaatgaaa
    11701 tcactttatt tacagatggt cgtgaaaaat tcgatgcgct gattgaagat atcaagcagg
    11761 cagaagacca tatccacttc cagtattata tttatcgcag tgatgcatta ggtgaagaag
    11821 ttcgagatgc attgacagag gcggcaagac gaggggtaaa agtcagagtc cttcttgatg
    11881 catggggttc cacacaagtt tcttccagct tttttcagaa tttgaaaaaa gcaggcggag
    11941 aagtcgcatt tttctttcct ctatttgttc cgtatattaa tcctcggatc aattatcgca
    12001 atcatcgtaa aatcgtagtt attgatggga aaatcggata tacaggtggg ttcaatgttg
    12061 gaaatgaata tctaggattg gtaaagaaat ttggttattg gcgagacaat catttgcgta
    12121 tttacggaga agcggtgtat accttgcaaa accgtttttt gatggactgg aattctcagc
    12181 atacaaaaga agtaggctat tctcccaaat ttttcccgtc cattcacact actggtgata
    12241 tagctgttca aatcgtgaca agcggaccag ataccgaaca tgaacaaatc aaaatgactt
    12301 atttgaaaat gatttcgtta gccaaacggg agatattgat ccaaacgcct tattacatac
    12361 cggatggatc gattcatgaa gcactgaagt tggctcttct ttcaggcgta aaagttcata
    12421 tccaaatacc taacaaacca gatcatcttc tcgtttactg ggcaacgtat tctttcgctg
    12481 cagagctgat cgagtatgga gcaaggatcg aaacatatga gaatggattt attcatgcaa
    12541 agacgatgat tatcgatggt ggcattgttt cagttggctc agcaaatatc gatgttcgtt
    12601 catttcgctt ggactttgag gtcaatacac tggtttatga tgaacgaatg gcttcacgtg
    12661 taagaaaagc tttttttgaa gactcgaaaa tttctacgca tctcacaaaa gaaatgtatg
    12721 aaaaccgagg aataatcatc aagatgaaag aaggattagc aagattgatt tcgccgctcc
    12781 tttaaaacat aaaaaggaca tgagaaccat caacagatgg agatctcgtg tccttttcta
    12841 acggggccat ttctgagagt acgtcagaaa tggagaaagc gtctcgcatg agcgaaatta
    12901 actttggggt atctcttgtt ttttggggaa agcaagaaat aagctaatat atgctattaa
    12961 aagagacaca tttcaaagcc agtatagcat agaaactttt aatgagatag ttttttttac
    13021 aattatgaga atttattttg ttatttaatg attttgattc gttttcatca agtaatgaaa
    13081 atgataaaat aaacatactt taggattaaa ggagatttct aatgaaaaaa cttaaattat
    13141 tcttaccaat aataggatta gccattcttt tatcaggctg ttcaaagtgg attgatcgag
    13201 gagaatccat tacggctgtt ggctcttctg ctttacagcc tttagtagaa acagttgctg
    13261 aaacttacca gacagaaaat cctggaaaat tcatcaatgt acaagggggc ggaagcggaa
    13321 ctggtttgtc tcaagtacag tcaggagcag tcgacatcgg aaactctgat ttgtttgcgg
    13381 aagaaaaatc ggggatcgat gcctcagcat tagtcgatca tcgagtagca gttgttggga
    13441 tcactcctat tgtgaacaag gatattggcg taaaagacat cagtatggaa aacctgaaaa
    13501 aactatttac aggcgagatc aaaaactgga gtgaagtcgg tggaaaagat cagccagtag
    13561 ttatattgaa ccgcgcttca ggaagcggaa cccgtagcac gtttgaaaaa tgggtattgg
    13621 acggagaaac agctgttcag gcacaagaac aagattcaag cggaatggtg cgccagatcg
    13681 ttgccgacac acccggtgca atcagctatg ttgctttttc ttatgtttcc gatgatgtag
    13741 atacgttgaa tgttaacggt gtagaaccga cagatgaaaa tgtgacaacg aacaaatgga
    13801 cgatttgggc atatgagcat atgtacacaa gagatcatcc aaaaaaactg acaaaagaat
    13861 ttttagacta tatcttatct gatgaagtac aagataacat cgttggagaa ctaggttata
    13921 tccctgtttc tcatatgaaa gtcgaacgtg attggcaagg aaatatcgtt aaagagtaat
    13981 ctttacacaa aatttacaaa cttagctaaa cttttacatg ttattaaaac caaattgatg
    14041 ttcaatttgt acactgagtg agtatgttaa acctgattaa gggggagtca tctgtggaag
    14101 atgtgaaaaa agtattatta acaaaatcaa aacgttcaaa aatggaacag cgtggaaaat
    14161 tcatcagttt tttatgtatc gcgctgatcg tgttggttgt attatctatt ttttattttg
    14221 tagctagtaa aggattggcc acctttttta ctgataagat caatgtattt gattttctgt
    14281 ttggtacaga ttggaatcca agccaaatcg gagcaaatgg gaaaccaatg gtaggggcat
    14341 tgcctatgat cacaggttcg tttattgtga cctttttatc tgctatcgtt gccacgccat
    14401 ttgccattgg tgcagcagta ttcatgacgg agatctctcc taaaaacgga acgaagatct
    14461 tacagccggt catcgagctg cttgtaggta ttccttctgt cgtttatggt tttatcggtt
    14521 tatcagttat cgtgcctttt gtcagaagta tttttggcgg gacagggttt ggtatcttag
    14581 ctggtacatt tgtgttgttc gttatgatct tgccgactgt cacaacgatg actgttgatg
    14641 cattaaaggc agtaccacgg cactatcggg aagcttcatt agcgcttggt gccacaagat
    14701 ggcaaacaat ctacaaagtc gtgctacgag cagccgtgcc cgggatttta acagcagtcg
    14761 tttttggtat ggctcgtgcg tttggtgaag ccttagctat ccaaatggtc atcggtaatg
    14821 cagcattgat gccaacagga cttactactc ctgcttctac attgacgtcc atcttaacaa
    14881 tgggaatcgg aaatacaatc atgggaacag ttgaaaataa tgtgttatgg tcattagcgc
    14941 tgatcttgct attgatgtca ttattcttta atatcgtgat ccgtatgatt gggaagaaag
    15001 gagagctgaa ataatgaacg caaaacgctc agataaaatt gctacaggtg ttttatatat
    15061 agtttcgggg atcatcgtat tgattttagc agctttacta ctttatatct tagttcgggg
    15121 aataccgcac atttcatggt ccttcttgac cgaaccttcc aaagcctacc aagaaggtgg
    15181 tggaatcggg atccagctat ttaactcgat ttatttgctt ttgatcacga tgatcatcag
    15241 ttttcctatt tctttaggtg cgggtatcta tctttcagaa tatgctggaa aaaactggct
    15301 aacagatgtg attcgcacgt cgattgaaat cttgagctcg ttgccttctg tcgttgtcgg
    15361 tttattcggt ttcttggttt tcgttattca attccagtat ggtttctcga ttatttctgg
    15421 tgcattggct ttgactgtat tcaacttgcc tcttttgact agaacagttg aggagtcttt
    15481 acaagcggtc cattacacac aacgagaagc aggattggcc ttaggtttgt cacgctggga
    15541 aacagtgatg aaagtggtgg ttccagaagc gacaccaggg attttgactg gtgtgatcct
    15601 aagttctgga agaatttttg gtgaagcagc tgcattgatc tatacggctg gacaaagtgc
    15661 acctgcgtta gattttacga actggaatcc attaagtgtt tcaagcccga tcagcatttt
    15721 ccgtcaagct gaaacattag ctgtccatat ttggaagatc aatacagaag gcacgatgcc
    15781 tgatggtgtt tctgtttcgg ctggcgcttc tgccgtgttg atcattgctg ttttactgtt
    15841 caacttcggc gctcgtgcga ttggcaaacg attataccga aaaatgactt cagcctaagg
    15901 agaagaagca aaatgaaaaa atataactgg aatgaaacaa atgtcatcac catgccaaaa
    15961 gagaaagaag tagcactata tacggatgat atacatgtct ggtatggcga caatgaagca
    16021 atcaaaggag tggatctgga atttgaaaaa aataagatca ctgcactgat tggtccttcc
    16081 ggctgcggaa aatctacgta tcttcgttcg ttgaatcgaa tgaatgatgg gatcgctaat
    16141 acgaaaatca ctgggaaaat catgtatcaa ggcgtagata ttaatgcgcc tcaagtggat
    16201 gtttatgaga tgcgcaaacg gattggcatg gtttttcaac gtcctaatcc gttcagcaag
    16261 tcgatttatg acaatattac atttgctttg aaacagcacg gcgaaaaaaa caaaaagaaa
    16321 ttagatgaaa tcgttgaaac aagcttgaaa caagctgcct tgtgggacca agtaaaagac
    16381 agcttggaca aaagtgcctt ggctttatct ggcgggcaac agcaacgttt atgcattgct
    16441 cgcgcgatcg cgatgaaacc tgatatcttg ctgctagacg agccggcaag tgctttggac
    16501 cctatttcga caggaacggt tgaagaaaca cttgtaaact tgaaagaaga ctatacgatc
    16561 atcatcgtga cgcataacat gcaacaagca gctcgtatca gcgactatac tgcctttttc
    16621 tatctaggaa aagtaatgga atatgacaaa actaacaaga tatttaccag accaaaaatt
    16681 caggcaaccg aagattatgt gtccggtcat tttggttaag acggaggcct caacatgaca
    16741 aaagaaatta tttcatctaa agatcttcat ctgtattatg gaaagaaaga agcactaaaa
    16801 gggatcgatc taagtttcaa tcaaggggaa atcactgcga tgatcggtcc ttctggttgc
    16861 ggaaaatcca cttatctgcg ttctttgaac cggatgaatg acctgattcc gaatgtaacg
    16921 atcaccggaa gtgttttata taaagacaaa gacatctatg gtccaaaaac agatgttgtt
    16981 gaactaagaa aagaaatcgg catggtattc cagcagccaa acccatttcc tttttctatc
    17041 tatgaaaatg tcatctatgg attgaaatta aaaggggaaa aagataaaaa agtccttgat
    17101 caagtagttg aagaaagcct gaaggcagcg tctgtttggg atgatgtgaa agacaaattg
    17161 cataaaagtg ctttatcttt atccggcggg cagcagcagc gtgtatgtat cgcacgtgtt
    17221 ttggcagtta atccggaaat catcttattg gatgaaccaa caagtgcgct tgatcctgtt
    17281 tctactggga aaatcgaaag tatgctgtta gaattaagag agcggtatac gatgatcatc
    17341 gtgacccata atatgtctca agcttcacgt atttcagata agacggcatt ctttttagat
    17401 ggtcacttga tcgaatacaa cgatacgaag aagatattca tgaatccaga aaaacaagag
    17461 acagaagatt atatttcagg tcgatttgga taaggaggaa acggaatgct acgtacacaa
    17521 tttgaagaag aattgctgaa tctccataat cagttctacg aaatggggat gatggtgagc
    17581 agcgccgtgc acaagtcagt tcgtgcatac atcaaacacg ataaaatctt agcccaagaa
    17641 gttatcgaaa acgatataaa tatcaataac atggaaacac gcttggagaa gaaaagtttt
    17701 gaaatgatcg cattgcaaca gccagttaca actgatttgc gtatgatcat tacggtcatg
    17761 aaagctagct cggatttaga acgtatggcc gatcatgcgg tgtctgttgc taaatccacg
    17821 attcgcgtaa aagggcagac gagaataccg gaaatcgaaa aagagatctc cgatatgtcc
    17881 gattatgtga aaaaaatggt ggacaacgtc ctagttgctt atgtcaaaac agacgaaaaa
    17941 gacgcacgta cgatcgccaa tatggatcaa agagtcaatg actatttcaa tcgaatctat
    18001 aatgcaacaa tcaaaaatat gcaggaaaat cctgagacag tcatcagtgg aacagactac
    18061 ttgaatgttg ccagttatct agaacggatc ggagactatg tgacaaacat ctgtgaatgg
    18121 atcgtctact tggctacagg gaaaatcact gagttaaata cgaaccacaa tgagattttc
    18181 taaactgaag ctgtgattat gccgtttgtt tatgaaaaga ggttgtgaaa aagctgttct
    18241 acatcaagta ataagaacag tcaaacaaaa aatagctcct catatttttc gtttggctgg
    18301 acttattacc gcagatgcaa gcttttgaac accgtttatt cgggaaaggg tttgtgacaa
    18361 aacatgtcac aaaccctttt catcatttca tagaaaggat aaagaatgca aaaaaaaatt
    18421 agcatcatca ctatattttt tatttgtgtg cttacttcat gggttattca gcatcaagcc
    18481 gctttatatg aagtacctgt catcgagata gaaaaagtac gaataaaaga ggatcatcaa
    18541 ttgattacag gaaaactgat gaactcggat caaaaaggag aatcgattta tttatcggtt
    18601 ccttatcaaa aaaatcaaat agaaacagca aatataaaag cgagacaaat gtatctagtc
    18661 caaatgcatg gagatgaatg gcagctagta gcaaaaaaaa atgatggctg gcttttcttc
    18721 ttcacaagta tcttcattgg cgccatgttg cttattggcg gaaaacaggg tctatttgct
    18781 ttaggaagtc tcatcatcaa tatcgtttta cttttacttt tgttgctcat ctttactaaa
    18841 acagaaggga tttctctatt aaataaatct atcctgttcg tcgttatagg gatgattatt
    18901 agcatattgg ctttagatgg atggaataga agcagtataa tcaaaatttc agctgcagtt
    18961 acgagtgttt ttttagcatt ttttatttgt cttttgacaa tgaatcattg gaaagaccaa
    19021 ggactgcgct atgaggaact gaattatctg acacgaccgt atcgttctgt ttttctttct
    19081 agcgtactga ttggaacagc tggaggaaca ctcgataccg ttatcacagt cattgcgaca
    19141 ttagaagaat tgactaagcg acaaccagaa ataacagcga aacagttatg gctttcagga
    19201 aggcaagtgg gtcgagatgt gattggctcg atgaccaata tccttttgtt cgtctatatc
    19261 agtgggtcag ttccatcgct tcttttatat ttaggaaatc aatggtcttt caaagaaacg
    19321 atagaacagc atttatcatt ggaattttta cgcgtcattg ctggcagctt aggaatagta
    19381 ttatcgatcc ccatctcggt cctctttttt ctgactgtaa ggaggctgaa acgatgaatg
    19441 tacttattat acttgttggg attttagcaa tcagcgtgct acttattggc ggtacgcaag
    19501 gtatgtatat tcttttaggc ttattcatca atttagggat ctttttcctg ttgttattcg
    19561 gttatcatca gaagtggccg atactggcat tgtcggtcat aggattttta ttgattgctg
    19621 tggttatctt attttttatc aacggttata atctaaaaat gcgtgcagct tttgtgagta
    19681 tactgatctt tttattttgt ttcctactat tgcttcctat cactgatttt ttagcgatcc
    19741 aaggttttac atcggtagaa ctagaagaat tatctggctt agataagact ttagcgattg
    19801 attttagatt acttacgaga tcgttgcttc tgattagtct tagtggtgct gttttagatg
    19861 cgagtgtagc aatttctagt gggacattcg aagtatatca ggcaaatccg caattatctt
    19921 tttaccaatt gcgccattct agtttcgcta ttgctaaaaa aatattggcg tcaacagtaa
    19981 tgacacttct ttttgcattc atgggaagtt ctttagcgtt gatcctctgg tttattgatt
    20041 tagacattcc ttttcagcaa gtgatcaatg aaaaatcatt tgttctagaa tatacgatgg
    20101 ctattcttac cacattgtcc gcactaattg ttcttccttt aacctgcgtg actacagcat
    20161 atctctttac aaaaaagaaa gaacaactca agatggagta aaagttacaa cttaagtcct
    20221 atgacatttt tactgaatca gtgcataata tggatgtaag gaaaagcttg caaacaattt
    20281 tgcttaagga ggcaatttcc atgaaagaaa gagaacgtat tttagattta gtgaaaaaag
    20341 gaatcctttc gactgaagaa ggcttagatt tattagaaag catggcaact gaaaaagacg
    20401 aaaagcaaat caaaaaagaa gcagacaagg taactgctag tcataaagaa aaagataagg
    20461 caagtcaatt gatcgataaa cttgaaaacg gcgaagaaga aatttctgag ccagttgatc
    20521 caaaggaaag agaaagacaa gatcaagaaa acttagaaaa gatcttagat gaactagcaa
    20581 ctgaagcgaa taaaacttcg gcgcgtctag atgaagtaaa tgctcaattc gctgacaata
    20641 aggcagcacg caatgagaaa caggaagcat tgatgcagct gaatacaaaa gaagaattag
    20701 gcgagttgac agaagaagaa ttagcacagc gtcaggcgtt agaggcagaa atcaaagagt
    20761 tagaagctag tggcgataca ctgttagaag aacaattgaa attagaagca gaattaaaag
    20821 atatccgtaa gaatcaatgg tctgagaaaa aagaaacgtt tactgataag tttgaattgc
    20881 cagatgattg gaaagatcaa gcaacagata cactgaatca agtaggcgaa aaaatgtcag
    20941 aagctggatc acagttaggc aaattcttga agaaaacatt ccaaactgtt tcagaaacag
    21001 tgaatgacaa catggaatgg aaagatgtca gcttacgtgt ccctgggatt gcgacaacga
    21061 aatttgagca tgaattttac tatgaagctc ctgcagcaag tatccttgat atcaaggcag
    21121 caaacggaaa cgtgacgtta aaaacgtggg acagcaacga tgtgaaagtt gaagctaaga
    21181 tcaaacttta cggaaaaatg ggtgctgaac catttgaagc attctctgaa cggagccaga
    21241 ttgaggttaa tgaagatcat atctccttcc aaattccaaa taaacgtgtg cgtgcagacc
    21301 ttgttttcta cttacctaaa cgagtatacg accacgcagc tattaaactt ctaaatggca
    21361 acatcatgat tgaaacattg gaagctaaag atatttatac aaaatctacg aatggtaaca
    21421 tcatcgtgga ccaattaact gcaacgatgc tggaagtaga aggtgtaaac ggcaatatcg
    21481 atattcgaaa cgggaacatc ttagattcta ttatcgaaac agtaaatggt acagtgacat
    21541 ttggtgcgac agcagaaaat ctttctgtgt ctttagtaaa tggtgatgta cgtcttacga
    21601 ttaaagaaga taatttgaaa aaagtagaag caagttcagt gaacggaaat gtcaaagtcg
    21661 ctttaccaga tggcatcggt ttggaaggac atgctaaaac aagtcttgga agtatcaata
    21721 gccgtctgtc caattacgaa gtagttcgtg agaaaaaaga acggacaaac caaatgttgc
    21781 aattccgtcg tgtttcagat gatgagatcg cgcaagtgca actttcaacg acaacaggaa
    21841 gtatctattt aaaagataca gataaataaa gaggttgtga aagagatgtt cagccttgag
    21901 caataagaag cgattttgta aaatagcttc ccctatttta caaaattgtg ccttattgcc
    21961 gataggctat ctcttgaaca ccgattaaga agaaggttgt cacaacgatt ttcttcattt
    22021 aaaatagtag aacagaggtg agacatgatg aaaaaaaagt tgacaaaatc caataaaaat
    22081 gttgttttga caggtacttt agcagggatt ggggaatata tcgggattga tcccactgtt
    22141 atccgtgtgc tttatgtatt cctaagctta gttgcttttg gaagtccaat cattttatac
    22201 attttattag ctttgattat cccatctgcg cgttctgcac gaacaaacta tggacataac
    22261 aatgcatatt atgaaaaaaa caattatcgt gaacaaacaa aaaaacgcaa agaagcggaa
    22321 aaaatcgatg atgacgaatg gagtgacttt taatgtcgta ctttcagcgt attttggtta
    22381 atacgttaac attcatatcg ttggctgttc tttttcctgc gatggtccat gtgagcagta
    22441 tttggacagc cgtccttgcc agcttcgtat tatctgtgtt gaacatgttt gtcaaaccga
    22501 ttctgacgat cctgtccctg ccctttacat tagtcacatt gggattgttt acgtttgtta
    22561 tcaatgcagc gattcttaaa atgacttcct tttttgtagg agcagaacat tttagttttt
    22621 cttcatttgg tgcagcgtta ttcgtagcta tcttgatgtc acttgtcaat gtaatcgtta
    22681 gtgaacataa cagcagaaag taaaaaaagc tgtgccgaga tctcggcgca gcttttttgt
    22741 ttatcgcgaa ttgtaaaatt aagttagaaa aataaaaagg catttatggt acactcaaat
    22801 tgtatttccg acgaaagaaa acaaaggagt gtaaccataa atgacctaca aacatcttac
    22861 catagacgaa ctgacaatga tagaatcata ttatcttcaa cataataagc cggttgaaat
    22921 cgctaaccga atgggacgtg ctatacaaac tatttataat gtagtcaata agttcaagca
    22981 aggtaagact gctcttgatt attggcacca gtataaagaa aataagaaaa aatgtgggag
    23041 aaaagtcatt caattacctg ctcatgaggt agattacatt aaagagaaag tcactcttg
//
LOCUS       DAFEEZ010000045        22857 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000045
VERSION     DAFEEZ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.046"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(104..1336)
                     /locus_tag="LP245_001857"
     CDS             complement(104..1336)
                     /locus_tag="LP245_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBL1519777.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1591..2160
                     /locus_tag="LP245_001858"
     CDS             1591..2160
                     /locus_tag="LP245_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1519778.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2338..2778)
                     /locus_tag="LP245_001859"
     CDS             complement(2338..2778)
                     /locus_tag="LP245_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBL1519779.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2936..3700
                     /gene="map"
                     /locus_tag="LP245_001860"
     CDS             2936..3700
                     /gene="map"
                     /locus_tag="LP245_001860"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBL1519780.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3732..4655
                     /locus_tag="LP245_001861"
     CDS             3732..4655
                     /locus_tag="LP245_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBL1519781.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            4731..5870
                     /locus_tag="LP245_001862"
     CDS             4731..5870
                     /locus_tag="LP245_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBL1519782.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            5863..6663
                     /locus_tag="LP245_001863"
     CDS             5863..6663
                     /locus_tag="LP245_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL1519783.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            6663..7490
                     /locus_tag="LP245_001864"
     CDS             6663..7490
                     /locus_tag="LP245_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL1519784.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7468..8202
                     /locus_tag="LP245_001865"
     CDS             7468..8202
                     /locus_tag="LP245_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1519785.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            8302..9168
                     /gene="rfbA"
                     /locus_tag="LP245_001866"
     CDS             8302..9168
                     /gene="rfbA"
                     /locus_tag="LP245_001866"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBL1519786.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9182..9754
                     /gene="rfbC"
                     /locus_tag="LP245_001867"
     CDS             9182..9754
                     /gene="rfbC"
                     /locus_tag="LP245_001867"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBL1519787.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            9776..10804
                     /gene="rfbB"
                     /locus_tag="LP245_001868"
     CDS             9776..10804
                     /gene="rfbB"
                     /locus_tag="LP245_001868"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBL1519788.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            10902..11753
                     /gene="rfbD"
                     /locus_tag="LP245_001869"
     CDS             10902..11753
                     /gene="rfbD"
                     /locus_tag="LP245_001869"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBL1519789.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            11787..13820
                     /locus_tag="LP245_001870"
     CDS             11787..13820
                     /locus_tag="LP245_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519790.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            13864..15143
                     /locus_tag="LP245_001871"
                     /pseudo
     CDS             13864..15143
                     /locus_tag="LP245_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
     gene            15353..16159
                     /locus_tag="LP245_001872"
     CDS             15353..16159
                     /locus_tag="LP245_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1519791.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            16171..17391
                     /locus_tag="LP245_001873"
     CDS             16171..17391
                     /locus_tag="LP245_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519792.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            17381..18967
                     /locus_tag="LP245_001874"
     CDS             17381..18967
                     /locus_tag="LP245_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL1519793.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            19006..21144
                     /locus_tag="LP245_001875"
     CDS             19006..21144
                     /locus_tag="LP245_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1519794.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(21512..22495)
                     /locus_tag="LP245_001876"
     CDS             complement(21512..22495)
                     /locus_tag="LP245_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBL1519795.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
BASE COUNT         7176 a         3899 c         4712 g         7070 t
ORIGIN      
        1 aaaaaacggt ggggttgttt agcgaaataa aggatctaag ccaatagctt agatccttta
       61 ttctatgctt tatattattt tttgcatgtg tgcgaaagta tactcaagcc caatcgccat
      121 ttcggaaaat cggtactgta gagccatctt cacggattcc gtcgatatcc atcttgtcag
      181 atcctaccat gaaatctacg tgggtttgac ttctattcaa tccagcttct gctaattctt
      241 catcggacat ttctgtaccg cctttcacac tgaaggcata agcagaacct agtgctaagt
      301 gattcgatgc gttttcatca aataatgtat tgaaaaagat gatgccagat tgagaaatag
      361 gtgaagggtc aggtacaagt gcgacttctc ctaaacgacg cgcaccttca tctgtatcaa
      421 gcagttttgc taagacatct tctccttgtt cggcagaaaa atcaacaact tttccatctt
      481 taaaagtaaa tttcataccc gagatgatgg tgccagcata actcagtggc tttgtacttg
      541 aaatgtaacc atctactcga tgactgtcag gtgctgtgaa cacttcttcc gtcggcatat
      601 ttgccatgaa tttttctcca cgagcattat agcttccagc gccttcccaa agatggtttt
      661 taggcaatcc gataatgata tctgtaccgg gagcagtata gtgaagggca gaaaattgtt
      721 ctcgattcaa ttcttctgct ttttttgcta atttttcatc atgcttcttc catgctaaga
      781 cagggtcttc ttcatagaca cgagtcgttt tgaaaatctg atcccataat gcctcaactt
      841 gtttttcttc tggcagttct gggaagactt ttgctgccca ttgtttacca gccgcagcca
      901 cgacagtcca actgacttta tttgcttgag ttgccttgcg taaattcatt agtgctttgc
      961 cattcgctga ttgataagac gctactcgat ggctatctac accagcaaat gcatcgggat
     1021 cggcagaaac aacgctgatc ctgcttgctc ctttttcaag ccattcatcc gcttgatcga
     1081 ttttagattg tggtacattc tcaatacgat ccgttgcagc atgtaaaaga aattctcttt
     1141 ggatctggtc gtcagtccat tgaacgataa cctcagcggc tcctagttta taagcttctt
     1201 gtgtgatcaa tcgagcaagg ggtgcctgtt ccacgctgat ctgtaaaaca actgtgtgtc
     1261 ctttttctgt ggctacgcca gtttctgcaa ttaagcgtgc atattttttt agaagttcat
     1321 taaaatcaga taacataata aaaattcctc ctcaccattt tttctggtaa ctattagcat
     1381 gataccattt aattatgatt caaacaatga ggctttaaat aaaaaaagga ggttattttt
     1441 ttaaggttaa gtttcatgat atatgttact acttgctatt tcagcttgtg aagaaaatca
     1501 aaaactaatt ttgcatatca aaaaaaacat gttacaatga aattaatcaa tggtggaagc
     1561 gttataaaaa aattaaggag attaaaaaat atggcaagaa aaaagacgat tactagagaa
     1621 cagattttgg cagctgctta tgaagtagct gccaccgatg gatttacacg atttactgcg
     1681 agaaacatcg cgaacaaaat gaattgttcc acgcaaccga tttatcttga gtttaaaaat
     1741 atggatgact tgagacaagc tctttttgag cagatctatg atcatttaca atatgaagtg
     1801 ttcactgttg agcatacagg gaatacgatt atcgatcttg cttttaatta tatccatttt
     1861 gcaagaagag agaagaagtt gtatcgttca ctgtacttag aagaatatgg tggaggaaaa
     1921 gagatgcaga atttctctta tacttacttt gtgaatacag tgaaacgcga tccagcttat
     1981 gtgaatcttt cagaagagca gatcgaatct ttgtataatg ggacatggat catagctact
     2041 gggatcgcag ctttgatgtc ttcaagcatc atccatccaa ctgatgaaca gattgaaaag
     2101 atgatccaag acagtataga tgctatcttg aaattcaaag aaccaatcga aatcgattga
     2161 atatactcaa aagttccaca aatcagtagg taacaagaga tgtgtcaaaa taaggaaaag
     2221 ttcgtttttc ttacagcgta tgcattttta actcccgaag aactcttcca tgaatgcaat
     2281 gaataaaaga gccatacaga ttgaataaat ctggatggct cttttattgc aagtatatta
     2341 aatttttgcg actagttctt tagcgaaagc ttctaaattt tcgatatctt cttcttcagc
     2401 attcagatcc actttaacat tttcggctcc ttttgatgcg cctgtttttg caaaagcagc
     2461 atcgaaatca tccaccgatt tgcagaattc atcgtaaaaa gtatcaccag atccgcagac
     2521 accgtaaatt tttcccaata gatccaattc ttgcaagtct tcataaaagt ctacgatctc
     2581 atcaggcaga tcgccatcat cgtatgtata agtagctact acgcaaatat ctgcctcctc
     2641 gaattcatct gcatctactt gggtacattc gttgatttcg acttcgatat ccagattttc
     2701 aaatgcttct gcaacaatat cggcgatttc ttcagtgttt cctgtcatgc tagcatatac
     2761 gatttttgct aaagccatga tgtgcctcct cgtttataat tatttaacaa ttatgaatta
     2821 taccaaaaca tcattgaaaa gaaaataaaa cctagagaca cctggggaat gtcatttggc
     2881 taaatgtatg ccgctatgtt aaaatgagag ggatttgtaa aaaggagacg aaaatatgat
     2941 tactttaaaa tcagcacgtg aaattgaaat gatggcagaa tctggagctt tattagcaga
     3001 tgtacataaa aatctgcgtg attttataaa accaggaatc acaagttggg atattgaggt
     3061 atttgtcaga aactatatcg agagtcatgg cggaattgct gcgcaaattg gctttgaagg
     3121 gtatgaatat gcgacttgta tcagtataaa tgatgaaatt tgtcatggat tccctcgtaa
     3181 aaagcctttg aaaaacggtg atttggtaaa agtcgatatg tgtatcgatt tgaaaggcgg
     3241 catttctgat tcttgttggg cctatgtagt tggagaatct acacctgaga tcgaccgatt
     3301 gatggaagta acgaagaaag ctttgtacat cggtattgag caagcacaag tagggaatcg
     3361 gattggtgac atcggtcatg ctatccaaac ttatgtagaa ggcgaaaatc tagcgatcgt
     3421 tcgtgatttt attggtcatg gcgttggtcc tacgattcat gaagaaccag cagttcctca
     3481 ttacggagaa gctggaaaag ggttgcggtt gaaagaaggc atggttatca cgatcgaacc
     3541 tatggttaat accggaactt ggaaaatgaa aatggatcct aacggctgga ctgcgtatac
     3601 aagagacggc ggactttctt gccaatatga acatacattg gctattacta aagatggtcc
     3661 aagaattttg acatcacaag gagaagaagg cacttattga tctatccagt caataggtac
     3721 gggagaggta catgaaagtt tggaacaaaa taaaacaaaa tgaaaatctg atgcgcttta
     3781 ttgagacgac tcaaaagcgc atcactgatt cagaaatgag tacgacctct gtcgtcgttg
     3841 cttattattt actcttgtct ttatttccat tgattattgc ttttggtaat attttaccgt
     3901 ttctccacat cgatcaagag actgtactga cctatttacg agaagtgatt cctgagaccg
     3961 tttaccagtt tatcggtcct gcaatcaaag accttttgac acaaagttca ggaggcttgt
     4021 tatccgtttc tgcattagcg gctttatggt ctgcaagtca aagtatcaat gctttgcaaa
     4081 ttgcgatgaa taaagcgtat ggcgtagaaa atagaaaaaa ttttttgatc gtccgtttct
     4141 tctcactaat tgtcattgtc ttgttcatga ttgctattag tggggtaact atcgttcttg
     4201 ggttgggaca gctgattttg gatgctattc agccaatcgt acaaataccc gtgaacttta
     4261 tcgatcagtt ccaaactttg aagtggccaa tcacattggt agctttattt gtcatcatgt
     4321 tcttgattta tttaattgtc cctaatgctc agttgaagtt gaagacgatc attccgggca
     4381 cgatcttcgc tactgtcggc tggatgctgt tatcacaagt gtttagtatc tatgctaggt
     4441 attttgcaac gaggatcagc ggttatcaga tcataggaag ttttattgta ctcatgcttt
     4501 ggcttaattt tgctgctacg atcatcattt tgggcggaat catcaatgca gttgttcaag
     4561 aatacgtgac gggtcatcaa atcaaaaaac gtcgagatcc aagccgaaaa tggttcaata
     4621 aattgaaaac taaattttct cataaaaaaa agtagaaaca agagttctta ttgtaaattt
     4681 atatcagtaa tttataataa ttatgactct taattaaagt aggtgcccat atgcttgttt
     4741 cttttagtat ggttataaga ttttttctga caattttatt atcactgata ttaacacctg
     4801 tattcaaaat catttcagta caaacaggta tggtcgacaa accaaatgaa agaagaataa
     4861 ataaagttcc aatgccttca gcgggcggac tgcctatctt tatttcattt gttatatcga
     4921 ctttattctt attccgtaaa attatccctc aatcgtatat tgtaccgatc ttgattgctt
     4981 ctttagtaat catagtcaca ggagtgctcg atgataaata tgagctgaca cctaaacaaa
     5041 aaagtatagg gatcttgatt gcttctctta ttatttattt tgtagcagat atacgtattg
     5101 attccttcac gcttcctttt attggatata tccaactagg ctggcttagt tttcccgtaa
     5161 cgattttttg gatcttcggt atcacgaatg cggtcaatct gattgacggt ttggatgggc
     5221 tggcggcagg gatttcattg atcggtttaa ttacgatagg aatcattgga tattttttcc
     5281 tccatgcttc tacagtgtat attccagttg ttattttctg tcttgtagca agtattatcg
     5341 gtttttttcc ttacaatttt tatccggcaa agatttattt aggcgataca ggagctctat
     5401 tcctagggtt tatgatggcc gtcctttcac tacaagggct gaagaacgtg acttttgttt
     5461 catcgatttc tttgctgatc gtcatgggag tgccggtaac agacacgttt tttgctatca
     5521 ttaggagaaa agcaaaccgt gtttcttttt ctacagcaga taaaaaacat cttcatcacc
     5581 gactaatcag tttaggcttt actcataaag gtgctgtcct gacgatttat gcgatggctt
     5641 tgatgttttc tttcacagct atggtcatga attatactgg aagaatcgga acgatcatat
     5701 tgattattgc catgttgttt gctgcaattt tattatttga attgattggt ctgatcaatg
     5761 agaaacatca gtttatttta aaaacattgc gatttttagg gaataaagag taccgtacgc
     5821 aagtaaaaca gaaatatttg aagaaatgga accgtcatat agatgaataa caaattaaac
     5881 cagccgatcc ttattagtat tgtgacggca aacagtgata aaatttttcg gacactagat
     5941 aattttattt caactgtaaa agatgaaaca gcagtaaaaa tccgaatttt tgacaacaat
     6001 tcacttcccg agtacaaaaa aagactaaca gagtatagga aatatcccta catcgatatc
     6061 tattttcatg atgaaaattc cggatttggt tatggacata atcacaatct gatagctagc
     6121 gattctcgct atggcattat ttgtaaccca gatattttag tggatgaaga gacagttaca
     6181 gcattggtct tgttattgaa agaacatccg gaatgtgcga tgttagcacc taagattctt
     6241 aatgaagatg gaacaactca gcacctcatc cgtgagcagc tggctgtttt tgattacgtt
     6301 ttgcgctttg tgcctttcaa atgggtcaaa aaaaagtttg acaaacgact ggctgtgttt
     6361 gaatgccgag gattgcctac tgatgctaat agttatgtac ggatgatctc aggtagtttt
     6421 atggtagctg atattgataa atttaaagag ataaaggggt ttgatgagcg tttcttcatg
     6481 tactttgaag acaacgactt gtgtttgagt tttgaaaaag caggttacaa gttattgtac
     6541 acaccctttt atgcagttat ccatttttac gggaagggtg cgcatcgaaa tgcaaaactg
     6601 tttcgcgtgt ttttgacttc tatgatgaaa tttttcaata agtgggggtg gcgttttttc
     6661 tgatgaaacc agaaatatta gtagtcgttg tgctttatca gcaactattc agtcaatctc
     6721 cagcttatgg accattaagc aaagcactta gcgaaaagca aattcagctt attatttacg
     6781 ataatagtcc tcaaaggcag caaaatgagc tgtttgaaaa agaaaatatc gtttatcatc
     6841 atgatccgca aaatcctggt ttagcggtgg cttataattt tgcgttgtct caagcagatg
     6901 aaggaacacg ttgtctcgtc actctggatc aggatacgag gctagtcgac gattattttg
     6961 aactattgcg taaagtaacc tttacagatg aatgtgttgc tgcagttccg atgatttttt
     7021 ctgggagccg acaagtttct cccctatatt cagatcgtta tatcaatcgt acagctcaag
     7081 cagtagaagt tgaaggccca acagctgaac gaatcatggc aatcaattca ggtgttgcct
     7141 ggtctgtcaa atttctaaaa aagattggcg ggtttaatcc tgctttttct ttagattttt
     7201 tggatcattg gctgttttgg aaagtggatc agttggaaaa aactgtggag atccttcctg
     7261 tacgaatgga acatgatctt tcggttttag actatgaaaa agtttcaagt aatcgatacc
     7321 gttctatttt acaagcagaa aatcgatttt atcatgaata tgatcaaagg catttatcca
     7381 gtcaccgacg acaattattg ttaagaacag ctaaacagtt cttgaccgtc aaaaaccggc
     7441 atatctggcg gatgactttg cgctcatatg ttaagaattg gaaggtgtga attcgtgcgt
     7501 tcggtttgta tagctacctt taatggaggc agatatttaa gagagcagtt agatagtatt
     7561 ttatctcagc tttcagcaga agatgaagta gtcatttctg atgatgggtc agtagatgat
     7621 acatgggata tattaactga atacgcagaa aaagataagc gaatccagct tttttcgggg
     7681 cctcgtcaag gattgatcgc taattttggt tatgcgatcc agcagacgaa aggagatcta
     7741 atctttttgg cagaccaaga tgatgtttgg ttggagacaa aagtgaaaaa gatcactgac
     7801 tattttgagc agaatccgga tcagctagta gtagtttctg atttaatcat tgtggacagc
     7861 gagctgcaag agatccatga ttcgtatttt tcgtttcgaa attccaaaga aggatggctt
     7921 aataatgtga taagaagtca ctatattggt gctggtatgg ctttccggtc ttctttaaaa
     7981 cccgatattt tgccgatccc gtcagaagtg ccgatgcatg atatgtggat tggtttgctg
     8041 ggaggaaaga agactgggtt cctaagagaa ccgttaactc tgtaccgaag acatgattta
     8101 aacgcgagtg agattgaaac acattctaaa ttacggcaaa aaatttcttg gcgtgttcat
     8161 ctgattacgg cgttgatcaa acgaaaatgg tttaaacgtt gataaaagat gtttaaatcc
     8221 ttaatatttc catgacaaat ataacaattg atgagataat aacaaagtga aatttgaaat
     8281 caaaaaggag agcagatatc catgaaggga atcattcttg ctgggggcag cggaacacgt
     8341 ctgtaccctt taacaaaggc aacatcgaaa caattgatgc cgatttatga caaaccaatg
     8401 atttattatc caatgtctac tctgatgttg gcgggaatca aagaaattct gattatttca
     8461 acgccacaag atacaccacg tttcaaggaa ttatttggaa acggaaatga tttaggactg
     8521 cagatcgaat atgcagtaca agaaagtcca gatggattgg cacaagcgtt tatcattgga
     8581 gaagaattta ttggagatga tagtgtctgc ttggtattag gggacaatat ttactatggt
     8641 ggcggtctgt ctaaaatgtt gcaacgagca gcttcaaaag atacaggcgc gacagtattt
     8701 ggctatcatg tcaatgatcc agaacgcttt ggtgtagtag aatttgatga gaatatgcaa
     8761 gctttgtcga ttgaagaaaa gcctgctcag ccaaaatcaa attacgctgt aactggcctt
     8821 tatttttatg acaatgaggt aatttctatc gctaaaggta tcaaaccttc agaacgtgga
     8881 gaactagaga ttacggatgt caataaagca tatttggata aaggaaaact atccgtagaa
     8941 cttatgggac gcggatttgc ttggcttgat acaggaacac atgaatcatt gcttgaagca
     9001 tctaccttta tcgaaacaat tgaaaaacgt cagaacttaa aagtggcttg tttggaagaa
     9061 attgcttacc gtatgggcta catcgataag gaacaattgc tggcccttgc acagccattg
     9121 aaaaaaaatc aatacggtca atatttattg aatttggccg ctgaataagg agtccttaca
     9181 gatgaaagta acagatacaa aattaacaga tgtcaaaatc gtagaaatgg acgtctttgg
     9241 cgatcatcgc ggtttcttca cagaaagtta ttcaaaagca aaatttgcag aacatggatt
     9301 gaaatatgac tttgttcaag acaaccattc actatcagct gaagctggtg tccttcgggg
     9361 gcttcatttc caaaaaggag aagctgcaca gacaaaattg attcgggtag tcactggagc
     9421 agttttagat gtagtagtgg atatccgcaa aggtagcccg acttatggtc aatgggacgg
     9481 atttatctta tctgaacata atcatcgaca gttgcttgta cctaaaggat atgcccatgg
     9541 attcgttact ttgacaccaa atgtgaactt cctttataag tgtgataatt actataatgc
     9601 agaagcagat gggggcatcg catttgatga tccagattta gcgattgatt ggccaattga
     9661 tccatcaaga gcgattatgt cggaaaaaga tcaccgtcat ccgacattaa aagaatttga
     9721 agcagaaaat ccatttgttt acggagaaat ctaagaatta aggagaaatt ttcttatgaa
     9781 aaacatcatt gttaccggag gtgccggatt catcggctct aatttcgttc attacgtggt
     9841 aaacaatcat ccagaagtgc atgtcactgt tttggataaa ctgacttatg caggaaacaa
     9901 agagaacttg gctggacttc ctagcgatcg cgtagaattg gtcgtaggag atgttgcaga
     9961 tgcagaatta gtggaccgtc tagtaaaaga agcggacgca gttgttcatt acgcggcaga
    10021 atcccataac gataattcat taaaagatcc tttcccattt gtacaaacga atatcattgg
    10081 tacgtataca cttttagaag cttgccgcaa gtatgatgta cgctatcatc acgtatctac
    10141 tgacgaggtt tacggcgatc ttccattacg tgaagacctg ccaggacatg gggaaggcga
    10201 aggagaaaaa ttcactgcgg aaacaccata taatccttca agtccatatt cttctacaaa
    10261 agctggttca gatctgttag taaaagcatg ggtgcgttct tttggcttac gtgcaaccat
    10321 ttcaaactgt tcaaacaact atggtcctta tcagcatatt gaaaaattta ttcctcgcca
    10381 agtaacgaat atcttaagcg gtattcgtcc aaaattatat ggcgaaggaa agaatgttcg
    10441 tgactggatc catacgaatg atcattcttc agcagtgtgg ctgattttga cgaaaggcag
    10501 aattggcgaa acctatctga tcggtgcaga cggtgaagaa gataataaga ccgtgatgga
    10561 attgatctta gaaatgatgg gtcaaccaaa agatgcgtac gaccatgtaa acgaccgtgc
    10621 aggacacgac ttgcgttatg caatcgattc gacaaaatta cgggaagagt taggatggaa
    10681 gcctgagttt acgaacttcc gtgatgggtt ggctgacacg atcaaatggt acgaagaaca
    10741 tgaagactgg tggaaaaaag aaaaagaggc cgttgaagca gcatatgcca aaaatggaca
    10801 ataatacaga gaaaatgtca ctgtattaat ggaaaaacac atgtgaggca ggcgctcgcc
    10861 tgtctctttt ttaaaataaa aatcaaggag cggataatca tatgttttta ttaactggag
    10921 gaaatgggca actaggtaca gaattgcgcc atttattaga tgaaaaaaat ctgcaatatg
    10981 tttcaacaga tgcaaaagac ttggatatca cagatgccga gaaaacaatg gcttacatca
    11041 cagaattaaa acctgatgtt attttccatt gtgcagctta cacagcagta gataaagcag
    11101 aagaagaagc aaaagaatta gatgagaaga tcaatgttga tggtacaaga aatgtagcac
    11161 ttgcagcaaa agctgtgaat gctcaattcg tctatatcag tacagactat gttttcgatg
    11221 gaaaaaacaa aaatgtagaa tacgaagtag acgaccaaac gaatccacta aatgaatatg
    11281 gtcgtacgaa attattaggc gaaaaagcag tagaagagat tttagaagac tattatatca
    11341 tacgaacttc ttgggttttc gggatctatg gacacaattt cgtcttcacg atgcaacgcc
    11401 tagcggaaac ccgcgacaaa ctgactgtag taaatgacca gtttgggcga ccaacttgga
    11461 cacgtacttt ggcagaattt atggtatatg tcatcgaaga aaaagcacca tttggtattt
    11521 atcatttgtc gaacgaaaat agctgttctt ggtatgaatt cgcaaaagaa atattgaaag
    11581 atacagatgt agaagttgca cctgttacgt cagaagaatt tccgcaaaaa gcaacacgtc
    11641 cgcagtattc agtcatgagc ctgaaaaaga cagaagagtt aggatttgtc ataccaactt
    11701 ggcaagaagc acttgcgcaa atgctggaag ctgccaaaaa aatgaataag taatttcctt
    11761 ttatcaaata gaatttggag catgatatgg aaaaacaaac aagaagtgca cgacgaaaag
    11821 aaaagccaaa agcgaaccag gcagattcga atttggtgct tgacctgttt ctaaaactcc
    11881 gctatcttat tggcgtttta gtcatcgtgg tcatcgttac ttttaattta aacggaagtt
    11941 cacttggtgt ttgggataaa tatgtgtcgc aaagagacga tgggaaaaaa actgatgtga
    12001 tttttggaca gaatcgggaa gtgcggtcag acgaatggct ggtgcagaca cctttttacc
    12061 tctcacaagc tgaagaggac tttccgttgg tgaacgagga ttattcatta aacggacaaa
    12121 acatgatcat tgcgtataat tctcctgtaa aggatattac ggttatcgga aaaccattca
    12181 actggggatt ctttttcctc ggaagagatc gaggactttc cttttattgg gcgatgaaat
    12241 tagtcgtcat ggtcttgctt ggattcgaag tactgatgat attaacgaag agaaaaaaag
    12301 ctctatcgct aatcggtgca tttgcgctga cattttctcc agcagtccag tggtggttca
    12361 tgcaacatgt gggcgatttg attttcttta ctttgggact gatgactgct ttttatcatt
    12421 atttctacaa tcatgataaa aaatggctac gaacgttgat gatgcttttg gtggttattt
    12481 tcggtattgg gtttatttta gtgatttacc cagcccatca agtgatgctg gcgtacttgc
    12541 tgatttttta ttttgttggc ctgcttattt actatagcaa gaaagtttca tgggatctgt
    12601 tggatgtagt gttgattgga ggggcagttt tatttattgg cggagtcatg gttcatttct
    12661 ggctaacgtc aaaagacgca ttgttagctt ctttgaatac cttatatcca ggaaaacggg
    12721 taagtactgg aggaaagtgg acgattggcg aatttttttc tttccttaca aattggaaaa
    12781 ttccttttga agatatcaac tattcgaata actctgaagt ggccctgttc tatcactttt
    12841 ttccaactgt attcctagca agtccatttg tgttatttgg caaaaaagat agcgaacaaa
    12901 agttactggg acgtattttg atgatttttt gtctgttttc tatcttttgg attaccgttg
    12961 ggttgccaaa atggctagca gaaatcactc tgctgtctta tgttcctcca ttaagagcca
    13021 tccttacttt tagttttgcg gcttgtttat tatcgatctg gtttatcgct tatatttgga
    13081 gagaagatgt tattcctatt tggtataaat tcattttgtt ggcagtaaat gcatggtctt
    13141 atttctatgc gattacgcat tcgaaaatgg ataattattt ttcggatttt gaaaccatcg
    13201 cagttgctgt gttgggaaca gtgattttag cttttgcatt atttggctgg agacgcttgt
    13261 tttacctcgc ttttgccgcc ttagttatcg tatctggctt tttcgtcaat ccagtcgtag
    13321 aaggtacagg agcgattttt gaaaaaacac tggcaaaaga aatccaaaaa atcgatcaac
    13381 aagatcctgg taaagtttgg ttgtctgaag atgaattata taacttcacc ccaacattgg
    13441 gagtgaaatc cttcaataca gtacgctttt atccagatat agctgcatgg aagaaaatcg
    13501 atccgaaaga agaatacgag aagtattata atcggtatgc tcatacaaga gcttttatcg
    13561 ctaaggaaga tacaaagttc attttagatc gtccagatat gttttcggtc acgttgaatt
    13621 ttgaagacgc agaaaaatta gggatcgact atgtgatcag taaacgacca ttaactgatt
    13681 acaaccaatt atatgaagcg cagttcacgc agctatatgg accggataaa gacggttata
    13741 tgatttttaa agtagaatat ccggattatc cagatgtacc acaaacacaa actcaggaaa
    13801 atcagctagt cgtacagtaa taggctagct gagaataatc ctgaaatgtt agtagaaagg
    13861 agagtggaga taattcaagc aatcgtacaa aaatttgtca acaaaatgag tgtcggtttc
    13921 ttgcttttgt tactgacgct agtctttttt gtttggacag cagggttagg ttttccagca
    13981 actttgttta tatataacaa tagttcatta cttatcgctt ttagtgtggc tattttgctc
    14041 attttaaatg tttataaagc aaaaggcgtc gattttcttt atctaggtgt tgcgcttgcc
    14101 cttttcattt tcttttctta ctttcgggaa ttaagaaatg agtctttatt tggagactta
    14161 ctgtttcctt tgattatttt attttgttta gtaattaaat ggatcgagtg gacaaaatgg
    14221 gatcgcggta tttatctgat tgtcttttcg gtcttcctcg gaatcacgtt tatcgtgtat
    14281 ttacagagat ccaagtacca gaaggacaaa gcatctgggc tccaggcaat tcgctttctg
    14341 atatttggat caatacgaat acaatcggaa gttctttgat gactcttgct ttattgatca
    14401 gtggatttgc cagttctttt gaacgatggt atgtacgaat catcggtgca gtagcagttg
    14461 ttgcagcttt tctcgggatt tgggtctgcc aatctagagg tgcattagtc gcgttgattg
    14521 tttttgcgat attggatctt ttacctaaat cgttgatgcg tgtcattcgt gcgccattta
    14581 ttgcttacac ggttacgatt cttttagctt tgccgatttc ttatctggcg gctgtctctg
    14641 aaaaagtcaa tttgtttacc ggtcgagaag atatttggca taaattctat cagacgctag
    14701 gagaaaaatc tgaacaaatt ttactaggaa tgaaaacatt tatcttccaa cgaggaaacc
    14761 aatttttagg aaaccacaat agttataatt ctattttgaa tatctatgga ttgataggat
    14821 ttgggattgc tgctttgctg cttatccttt ttattggtcg cttaacgttg aaagcagatt
    14881 tatccaacgg gcagatgact tttatctggg ccttttttgc ggtgatgatg cagtcattta
    14941 tggaggatac attgacttca taaccatggg ttccgattat ttatatcctg ttggctatgg
    15001 ccgttcatcg atatgatgaa ccagaagttg cggaggaatt ctatgttatg gaagaggcat
    15061 atgacgatat gacttatgat gatacatctt atgaggaaca accagatagc gctcattctt
    15121 ccaggatcca acgctatcat tgataggcac aaaatacgag agaggctgtg acaaccgtcg
    15181 cagccttttt tggtttattg caattgtcta gcatcttctg taaaatagaa acgttagaga
    15241 aaatcttgta tcatagaaaa ttaagaaaga aataagaacg cagctcggta ccaaaaatat
    15301 ggtaaaatgg cacttgactg taattcactg aaaatcgctt ggaggaacac aaatgtttaa
    15361 agatttgtat ttatttatga aggacattta tcagaacaga aaattattgc tacagttttc
    15421 gatcaatgac ttcaaatcaa gatatgcagg atcgttttta ggaatcttat gggcgtttat
    15481 caatccgcta tttactgtat tgatttattg gctggtattt ggtgttggac tgaaagcaca
    15541 aatgatcgat gcaaaatacc catttatcgt atatttagtt accgggatga ttccctggtt
    15601 cttcttctca gatgcatttg catcaactac ggttgttttt cgggaatata cttatttagt
    15661 aaagaaagtc gtattcaata ttcgtatctt gcccacgacg aaaatcctat ccaatctgta
    15721 cacccattta ttcttcattc tgattggcat agctgtcgcg cttataaatg gtatatatcc
    15781 ttcagcaatg tctttacagc tgatttatta tttattttgc atgtgtgctt tcttgacagg
    15841 attgacttgg ctgacggcat cgatccaacc atttttacct gatatcatgc aattaattac
    15901 gatcgtgctg cagttgatca tgtggacatt accgatatta tggagcccta atcagtttga
    15961 ttcaggtctt gtaagcatat tgaaattaaa tccgctgtac tatgttgttc aaggttatcg
    16021 tgagtcattt ttaagtgaag cttggttctg ggagcatgga acatatactt tgtatttctg
    16081 ggttttcacg ttagtaatgt tcgtaatcgg ctctgcagtg ttccgtagat tgaaaccaca
    16141 tttttcagat gtgctgtaag gagaatagct atgacagaat atgcaattag actaaaagat
    16201 atcacaaaat cttataatat gtacgcaaaa ccttcggatc gatttcgtga agccctcaat
    16261 ccttttaaga aatcctatca tgatgtattt tatgcgttga aaaacgtgaa tgtagaaata
    16321 aaaaaaggtg agatgatcgg tttcgtggga gaaaacggat cgggaaaatc tacaatgttg
    16381 aaaatcatta cgggagtact gacaccaaca tccggcacga tggaaatcga aggaaaaatc
    16441 tcagctttgc tagaactagg atcaggattc aatcctgagt attctggcta tgaaaatatc
    16501 tatttaaatg gaatggttct aggattttca agagaagaag tcgatgaaat ggtcgatgat
    16561 atcattgaat ttgctgacat cggagaccat atttatcaac ctgtaaaaac ttattcaagc
    16621 gggatgttcg ttcgtctagc ttttgctgta gcaatcaatg tgaatcccga tattttgatt
    16681 gtggatgaag cattggcagt aggcgatctt gaatttcaac taaaatgtat ggaaaaattt
    16741 acagaaatca agaactcggg aaagacgatt ttattcgttt ctcatgatat cagttcgatt
    16801 cgtcgttttt gtgatcgttc ctattggttg aaaaacggag aagtcgtcga atatggcgat
    16861 acgatggaag taacgacgaa ttatgaaaac tttttaaaga aaaaatcagt taaaacagtg
    16921 gatcggaata aaaaccaagt agaacggttc gccgctccag atatcgtcga cgtgacgaaa
    16981 gcggaattgt tggataaaga caaaaatccg gtggatatgc tggaacaagg agaaaaacta
    17041 tacgttaaag taacttatga agtaaaagat gatacaatca aaaatccggt tttaggaatt
    17101 gcgctacgaa cagtcgacaa tttttatgta tgcggactta atactctact agatggtatc
    17161 aagattcctt ggaaaaaagg agagaatatc ttttatctgg agtatgaaaa gttaggtttg
    17221 ttagctggtg aatattattt tgacgttgcg gtctttgaag aaaatgcaac ggttcctttg
    17281 gtatataaga caaagtacat gaacttgttt gtcagcggtt cttatatcgg agaaggcatc
    17341 gtggtcttag accataaatg ggaagaaggg actcatagca atgaaatatg attttgaaat
    17401 ggacctagat gaacaaagca gtgtgggaaa aattgccgca cagatcaaac caggaagtaa
    17461 agttttagag tttggtcccg gaaacggccg attaacgaaa catttaatcg gagcaaaaca
    17521 atgtgaagtg agcattgttg agttagataa ggaattgttc gattttgtca gcgaatttgc
    17581 tcaagatgga ttttatggtg atatcgaaag ttttgagtgg gcaaactatt atgctggaca
    17641 gacatttgat tacgtcttgt ttgcggatgt tttagaacat ttggtagatc ctggaaaaac
    17701 attgaagaaa gtcagagaat ttttgaatga agaaggagag atcctgatta cattccctaa
    17761 cttggcgcat aattctgtca tgatcgattt gttcaataac caattgccgt gggcttctta
    17821 tggtctccta gatgaaaccc ataattcttt ttatactcat gatggcttcc aaaaagtttt
    17881 tgaaaaagcg ggattattca ttaatattga agattatttg tacttagctg taggtgatac
    17941 agaattaaaa tcaacttatg aagaattgcc ggaagctgta cgctatgatt tcaaaatgcg
    18001 accatttggt gaagtctacc aatacttttt ctcattgatg aaacatccag tagcacaaag
    18061 ttccattgca gagccacaaa attctaatta tgtaaaagtg ttagaagtaa cccagcaaac
    18121 gaaacaagat gaaacaatcc aacaaatacc attcaataat ttcacagggg aaaatgagac
    18181 actaagtttc cccgtatcag aaacaacaga aagaatggtg tttcgcttcg cgcaacaacc
    18241 tagctttatc gaattcagcg cagaagctgc cggagaaaaa ctaacattta tcgattcgaa
    18301 tgctgtagtc aaaacagtaa atgattgtta tttgtttgat gggaaagaat taccagagtt
    18361 cgttctaacg gatatttctg ggaaagaagt gactatccat tgtcactatc gctttatcgg
    18421 ggaattgaca ccaacaatga aagaattgtt ggaaacgatt cgtcccatgg ctgaagtcac
    18481 aaagcagctt tctgagaaaa atgacgaatt agaaagagaa aatcatcatc ttcttgagga
    18541 aaatacaaga ctagaccata cgttaaaaac aaccacaaat cgctattgca cattgttgga
    18601 aagtgatgaa tggacaataa aacatagact aggacgacgt aagaaagaaa cttcgaaaaa
    18661 aatccaagaa aaagaacttt ctatatgtat tgacgagaaa atctgggatg cagaaacaaa
    18721 aatattaaaa atcatcggat ggggaatcgc taattcggat cgccagccct tgtcctataa
    18781 gttatcagct gaccaatcgc catttttcga agcaattcct gtttcacgag aagaagtcaa
    18841 tcaagcagaa cagctcgcaa aaggaacaga agcgggattt gagttacgaa tcctttgcga
    18901 gcaagaacgt tcattcttag tggaagcagt agctcaaaat ggccaatcat ggatcattga
    18961 aatgtaaata atgattaact tataaagata aggagtaaac gaatcgtgca aaaaaaagaa
    19021 attgccgtat ttatcgatca aatcactcgt gaacgggcca ctggcgattt gcttattgtg
    19081 ggctgggcaa ttgatgaagt gaccaaagaa atccctacga taaaggtaga aaaagaaaat
    19141 gtgattgctg aagcaacaca tgtcgtaaga ttggatatca atcatttata taatcttgat
    19201 gttaagaccc aaagcggttt taaggtacgt ttatcaggga aaatgagagg aaaagccatc
    19261 ttagacttcc aaacagcgag acatcaaaat ggcatagctg tgaaattaaa cggtaaatac
    19321 ccttatgatg acggcattga atcttcatgg gaaagaaaaa aaagattact gaaaaaaggg
    19381 ataaattatg caaggactca tggcgtaaaa aaagcgatcc gtcgggtcaa attggaattg
    19441 aagccaggat cgatcgacta tgcagagtgg atcagtcgtc atgagaaacc agatttgaaa
    19501 gagcaaagga aagaagcaca aggatttgcg taccgtccat tgatttccat acttatgcct
    19561 gtctataacg ttgaaatcaa atggctcgaa aaatgcattg attcggtact ggatcaaacg
    19621 tatgatcatt gggaactatg tatcagtgat gatgcttcta ctgatccagc tatccgaaag
    19681 tgtctggaat cctatcaagc aaaagatgat agaatcaaag tcgttttccg aaaagaaaat
    19741 ggacacatca gtctggcaac taattctgca ttggaaatag cagaaggaga atttatagca
    19801 ctcttagata atgatgatga attaccgcca tttgcattat atgaagtggc aaaagtgcta
    19861 aacgtacatc cagaactgga tgtgatctac agtgacgaag ataaaatcga tgcagatggc
    19921 aatcgctttg atccgcattt caaagcagac tggtcgcctg atacattgat gggaaataat
    19981 tatatctctc acttaggcgt atatcgaaca agcattgtta aagaacttgg cggtttccgt
    20041 aaaggctatg aaggttctca agattatgat ttggtccttc gtgtgacaga acaaatccct
    20101 gcagatcata tttaccacat tgaccgagtc ttgtatcatt ggcggacgat cccaggatca
    20161 actgcaagta atggcgaagc caaaagttat atctatgatt ccggagtgaa agcattgaca
    20221 gatgccctgt ctagaagaaa catcaaagga agcgtacgtc ctggcagaat ttctggattt
    20281 tatgagattg cttatgacgt cttgcaagag gatttggtca gtgtgatcat tccaacgaag
    20341 aatggctatg aagatctaaa aacttgtgtg gattcgatca tcgaaaaaac gtcttattca
    20401 aattatgaaa tcattattgc ggataacgga agtacagatc caaaaatgca agaattattt
    20461 gcagaataca agcatcagct gaaagaccgc tttatcgtag aattgattga cattccattc
    20521 aattattctc gaattaacaa tttagcagca gaaaaagcaa acggcaaata ctttttattc
    20581 ttgaataacg atacagaagt gattgagcca gattggatga cggtgatggt ttcttatgca
    20641 cagtttgatc gaatcggctg tgtaggagca aaactgtttt atccagatga tacaacgcag
    20701 catgcaggag tattattagg aatcggtggt gttgcagggc atgcattgaa taactatgat
    20761 cgaacacatt gtggttattt cggccgattg gtcattgacg tcaattactt agcagtcact
    20821 gcagcttgta tgatggtcaa ggcagctgac ttcaatgctg ttaacgggtt tgatgaaaca
    20881 ttagaagtag cattcaacga tgttgacttg tgcttgaaag tttatgaact gggtcgttac
    20941 aatgtctatg cacatcaagc agaattgtac catttcgaat ctaaatcaag aggttatgaa
    21001 gatactccag aaaaacaaag acgttttgct ggtgaaatca aaaaaatgca agataaatgg
    21061 ccagcatata ttgcgcatga tccattttac aatgataatt taacaaaaga aggaatcggc
    21121 gacttttcgt tgagaccaga ttaaactata ataaaaagct gttatgttgt gattcgctcg
    21181 cacataacgg ctttttatag ttttttgtca aaaaaaggca gaaggtgccg actcaaaaaa
    21241 ataagtcgag gttgggacag aagtgtttaa ctccgagaaa taagaagaaa ttcacgaaaa
    21301 ttgcttttca aatttttgtg aatttcggct tatttaagaa gaagttgctt ctgctcccac
    21361 cgtttattcg tttttaaaga atgagacaaa agtgtttctt acttttgtcc cacgctctta
    21421 ttcatgctca gagcgccaat agatacaaaa tcatagccaa agtttcacga accctagctg
    21481 tcaaagaatc gatattttat tttaatatag gctattttaa aataaatggt ttaaggtatt
    21541 cctctacaaa agccactcta tcaattatca tgggtttaaa ataagaagtg atggagataa
    21601 ccagattgtt cttagcgtca atataaagaa catttccact attaccaatt gctgaatata
    21661 tttcgttctc agaatctaat acccaccata aatagccata tctcatattt tgtaagtctt
    21721 ctaaagcact ggttctaggt ttgaacatct cgtttatcca catgggtggt acgatttgtt
    21781 ttcctttata catcccttta tttaggcata atacaccaat ttttgccaga tcacttgccg
    21841 ataaacacaa accatatcct gccgtcccga tatttagtgg atcacaaaac cagacattgg
    21901 ttttaggaga cttatccatt gtaaactgct tatgttcttc agctgtttca gcataataat
    21961 tgacatggtt tggtatccct ataggatcaa atagatactt attggcaaaa tcaacagttg
    22021 ttagcttact tgtctgatac aacaagccag ttaatatgtg taaacagaca gtttgatagt
    22081 tgaattcgcc ggttatacct tttcttcctc ccaataaatc tagtgatgtt tttgtccaat
    22141 cttcacttga acagactttt gtccatggat cgcctttaca tttgtagggt gctttcattg
    22201 ttagcaagtg cttgattgta atagcgtaaa tagttttctc cccgcgtttc actttatact
    22261 ctggaaaata atctaatact ttatcatcga tacttttgat taatccttgc tctaaagcaa
    22321 tgccaatcag caaagataca atacttttcg ttgctgacat gatatgacaa gtatcgtctt
    22381 ttttataacc attccattca tctgtataaa cttctacccc atccttatat gcgacaattt
    22441 gacatatatt tggttgtcga aaaccaataa aatcatgcaa ctcttgttta ttcataagat
    22501 attacctcac tttcttctat aagcataatg tcattaaaaa tcgatttcaa ttttttcgat
    22561 tcttcacgta atacaggtat tcttatggac tagacagcgc tttgggaaga tggattctct
    22621 gaaaaatata aaggttcact ttatgagtgg ataaaaaaag cagcaaatac ttcgacttct
    22681 ttaatttacc aacattagtg aaaatcgatt catctggaga tttgtaattt agagtccttg
    22741 tcttgattag aggtgtataa agctttttat tagacatttt taaattccat tacaatttgc
    22801 ttataaacta ggtttttaaa ggtgactatg gtaagataat agagatatta ttttgtg
//
LOCUS       DAFEEZ010000046        21266 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000046
VERSION     DAFEEZ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.047"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(27..1523)
                     /gene="lysS"
                     /locus_tag="LP245_001877"
     CDS             complement(27..1523)
                     /gene="lysS"
                     /locus_tag="LP245_001877"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBL1519796.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="LP245_001878"
     CDS             complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="LP245_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBL1519797.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="LP245_001879"
     CDS             complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="LP245_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBL1519798.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3743..5842)
                     /gene="ftsH"
                     /locus_tag="LP245_001880"
     CDS             complement(3743..5842)
                     /gene="ftsH"
                     /locus_tag="LP245_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBL1519799.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGARIPA
                     GVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETAKKNA
                     PAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATNRSDV
                     LDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGFAGAD
                     LENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYHEAGH
                     TIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGGRTAE
                     EIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQTKAY
                     SEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKSLFEH
                     GVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEENKAEH
                     DSDSQQSEDNHSDDQYK"
     gene            complement(5932..6477)
                     /gene="hpt"
                     /locus_tag="LP245_001881"
     CDS             complement(5932..6477)
                     /gene="hpt"
                     /locus_tag="LP245_001881"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBL1519800.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6477..7922)
                     /gene="tilS"
                     /locus_tag="LP245_001882"
     CDS             complement(6477..7922)
                     /gene="tilS"
                     /locus_tag="LP245_001882"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBL1519801.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8042..8512)
                     /locus_tag="LP245_001883"
     CDS             complement(8042..8512)
                     /locus_tag="LP245_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBL1519802.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8558..8983)
                     /locus_tag="LP245_001884"
     CDS             complement(8558..8983)
                     /locus_tag="LP245_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBL1519803.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9050..9319)
                     /locus_tag="LP245_001885"
     CDS             complement(9050..9319)
                     /locus_tag="LP245_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBL1519804.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9330..10925)
                     /locus_tag="LP245_001886"
     CDS             complement(9330..10925)
                     /locus_tag="LP245_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL1519805.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10940..14461)
                     /gene="mfd"
                     /locus_tag="LP245_001887"
     CDS             complement(10940..14461)
                     /gene="mfd"
                     /locus_tag="LP245_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBL1519806.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14478..15038)
                     /locus_tag="LP245_001888"
     CDS             complement(14478..15038)
                     /locus_tag="LP245_001888"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBL1519807.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15391..16365
                     /locus_tag="LP245_001889"
     CDS             15391..16365
                     /locus_tag="LP245_001889"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBL1519808.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16535..17935
                     /locus_tag="LP245_001890"
     CDS             16535..17935
                     /locus_tag="LP245_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBL1519809.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18013..18735)
                     /locus_tag="LP245_001891"
     CDS             complement(18013..18735)
                     /locus_tag="LP245_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1519810.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18814..19320)
                     /locus_tag="LP245_001892"
     CDS             complement(18814..19320)
                     /locus_tag="LP245_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL1519811.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19443..21242
                     /locus_tag="LP245_001893"
     CDS             19443..21242
                     /locus_tag="LP245_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBL1519812.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
BASE COUNT         5916 a         4657 c         3832 g         6861 t
ORIGIN      
        1 gaattcctta gacagctttt attcgattat ctcattgttg ggaatagcaa aacatcccga
       61 attgattgtg catcagttag caacattact aatctgtcga tcccgatgcc tagaccacca
      121 gttggcggca taccgtattc taaggcttcc aagaagtctt cgtctacacc gtgagcttcg
      181 tcatttccta gttcacgttc tttttcttgc gcttcgaatc tttctctttg atcaattgga
      241 tcgttcagtt ctgtaaaggc attagcaaat tcgcgcccca ctatgaatag ttcgaatcga
      301 tctgtgaatc gaggatcttc tggatttttc ttcgctaaag gcgaaacttc gactggatgt
      361 ccgtatacaa acgtcggttg tgtcaatgtt tcttcaacaa atgtttcaaa gaattcattg
      421 ataacatgtc cgacacccat agcttcggtt acttctacat tgtgtttttc ggctaaagct
      481 aatgcttctt ccaatgtcat ttcttgccag aagtctacac cagtttgttc tttgattgca
      541 tctaccatat ggatgcgttt aaagtcactt tctaagtcga cagcttgtcc atcatatgtg
      601 atttttgctg ttcctagtac tttttcagct gcgttacgga taataccttc tgtcagattc
      661 attacatcat tgaaatcagt atatgctgtg tatgcttcta acatcgtaaa ttctggatta
      721 tgtgtagtat caattccttc attacggaaa acgcggccga tttcataaac tttttccatt
      781 ccgccaacaa ttagtcgttt taaatgaagt tctagcgcaa tacgcaaata taaatcaatg
      841 tccagtgcat tatgatgcgt gataaatggg cgtgcggcag ctccacctgc ctcattgtgc
      901 aatactggtg tttctacttc aatatagcca ttgccatcta aatagcgacg gatttcgctg
      961 ataatttggc ttcgtttcat aaatcggtca aagctttcgc gattactgat taaatccaag
     1021 tagcgttgtc tgtagcgttg ttcaatattc gttaagccat ggtatttatc tggcagtgga
     1081 cgaagtgctt ttgacaaaat cgtgatttct gaagctttga tagaaacttc gcctgtgtct
     1141 gttttcatga tttgtccagt tacaccaaag aaatctccaa ggtctgcatg tttgaatact
     1201 tcataggcct catcacctac ttggtctttt cttacataaa tttgaatttg gccttcacga
     1261 tcttgtagat gcgcaaatcc agttttccct tttcctcggc gagtcatcat acgaccagct
     1321 acactagcgg tcaatcccat ttctgctagt tcttcttttg ttcttggatc aaatagttca
     1381 tgcaattctt ctgagttgtg cgtgcgttca aatcgttttc caaatggatc gattccatct
     1441 tcacgcaatt gttccatttt ttgacgacgt acaagcattt gatcatttaa atcttctact
     1501 tgatgttgtt gttcctgtgt cacaaaagtt cctccattct catgttaatc tctttcctat
     1561 aatgccaatg aaacacaaaa aaagcaagcc gaacttggaa tttcggcttg aaaattcacg
     1621 aaaaacttag aaatcacaac gtttgtttca atagtacttt ttccgctttt tctacaaatt
     1681 gatccagcag gtcattgatt tcttgctgtt tttctgtctg attgattgct actttcactt
     1741 tcgctgctcg aggaatccct tttaaataat aagccgcatg tgttctgaat tctctacaag
     1801 ctactttttc tcctttgaga tctgctaagc gttgtaaatg aagtttagct gtagcaattt
     1861 tttcggctgg tgttggttca ggaatcagtt ctcctgtttc gagataatgc tgtgtgcggt
     1921 gaatcatcca tggattgccc agcgctgcac gaccaatcat cacaccgtct gcaccgacat
     1981 agtcaagcat ccattttgca tcttctggcg ttttgacatc cccgttcccc ataaatggga
     2041 tcgtcaaatg ttttttcact tctttcaata cttcccagtc cgcttttcct tcatacatct
     2101 gaacccgtgt acgtccatgc atagcgatgg cacttgctcc agctgattgt gctgctaatg
     2161 cattttctac agcaaagacg tgctcttcat cccaaccaat acgcatcttg attgttactg
     2221 ggatatttac tgctgaagaa acagcttgga ccatttcgta tactttctca ggatctaaaa
     2281 gccattttgc tcctgcttct gctttgatta ctttatttac tggacagccc atattgatat
     2341 ctattatatc ggcagctgtg ttttcttcga caaattgagc agcttcaact agactatctt
     2401 tatttccgcc aaatatctgt aaacttaatg gatgttctgt ttcttcaatg tggagcatct
     2461 ctaaagtttt tttgtttctg aaatgaatac cttggtcact gatcatttca catacgacta
     2521 agcccgcacc aaattctttg acagtgactc gaaatgctga atttgttatt ccagccatcg
     2581 gtgcaacaac gacacgatta gggatttcca cattgccaat tttccatgtg tgttccactt
     2641 aaatccctcc taaggcttct ttcttcaatc catctaattc ttcttcgcta tacttgtatt
     2701 tgttattaca gaaagaacaa accgcttctg caccgtgatc ttcgtctatc attgcttgga
     2761 tttcttctgc acctaacgcg ataattgctt ctgcaaattt ttcttttgaa cagtcacatt
     2821 tgaattgaac aggcattttt tccaaaatgt tcaattcttc tgtaccaagc aatcctttca
     2881 atatttcttc tggtgtctgt ccttcatcta agagggtaga gattcttggt gtcgttttta
     2941 attgttcttc gatcttgctg attgtttctt catcggcacc tggcatgatt tggatcatga
     3001 atcctcccgc cgtcttgatg ctgtcgtcag tattgaccaa tacactcagt ccaacagctg
     3061 aagggatttg ttctgagata gcaagatagt aagtaaaatc ttcagcgatt tctccagaaa
     3121 caatcggcgt ttgcccagaa aaaggttctt ttaatcctaa gtcttttgtg acagtaaaca
     3181 ttccttgtgt tccaactgct ccccgcacat cgattttacc ttcactattt agaggaagac
     3241 tgagatgcgg atttttgatg taacctttca catctccctt tccatttgca tctactacaa
     3301 ttcctgttgc tggaccatcg ccttggattc gaacagttag tttgtcttct cctttgagcg
     3361 tcgcaccaag tagcagacta ccgaccaatg tccgtcccaa agcagctgag gaggtgtgcc
     3421 aagtatcatg acgtctttgt gcctccgcta cggtatttgt tgcttgaacg gcgtatgctc
     3481 ggacgaatcc gtcgtgagca agtgccttaa ccaaataatc tttcatttgt tatgtactcc
     3541 tttttccgtt tttaaactca tagtgaatca tactagcaac tactgctttt ttcaactttg
     3601 gaatgcttct tttaaaaata attcagaatc atctagaaaa caggacatca ccctatttac
     3661 aacttaaata aagaaatctc ccgaaaaccg gtttttgttc cggttttcgg gagtcatatc
     3721 agatcaattg acctatattt ttttatttgt attgatcgtc tgaatgatta tcttctgatt
     3781 gttgagaatc tgaatcatgt tctgctttat tttcctcatt cagttcatgt tttgcttctt
     3841 caaaatcacg tttttcttcc gcttgttttt cagcgtcttt ttcttccaaa gcacgttttg
     3901 cttcttcaaa agttttcgct tctttttcgc ttggataatc atttgactca gtaccttcag
     3961 gcatcacacc gtgttcaaac aatgacttga ttgctttggc atccaatgtt tcgaattcca
     4021 aaagtttttc agcaatcagt ttatgctgtg cacgatgagc ttcgatgatt tctcgagctt
     4081 tatcatgagc ttccatcaag atttttcgta cttcttgatc aatctcgaaa gcgacttgtt
     4141 ccgagtaagc ttttgtttga ccatagtcgc ggccaacaaa cacttgatgg tttccttcat
     4201 attgaacagg acctaaacga tcactcattc catattctgt taccatgctt cgtgctagag
     4261 ctgtcgcttg ctcaaagtca ttggaagcac cagttgattg gacattgaag atgatttctt
     4321 cagctgtacg tccaccaagt aagcctacga tttgttcaaa catatcttct ttcgtcatca
     4381 agaactgatc ttcttttggt aaagcgatca tatatccgcc ggcgcgtccg cgagggatga
     4441 tcgttacttt gtggacgacc cgagcgcgac tcaatactaa tccgacaatc gtatgaccag
     4501 cttcgtgata agcaaccatt tcgcgttctt ttttgctgat tacgcgatct tttttagctg
     4561 gacctgcaat cacgcgatct tccgcttcat cgatatcaga agcatcgatt ttctttttat
     4621 ttcttctagc agctactaac gctgcttcat tcaagacatt ttctaaatct gctccggcaa
     4681 aacctggtgt ctgttgagcc acaactttca agtcaacgtc atctgccatc ggtttattcc
     4741 gtgcatggac tcgcaagatt gcttcacgac cttttacatc tggacgtcca actaaaatct
     4801 ggcggtcaaa acggcctgga cgtagtaacg ctgggtctag tacatcagaa cggttggttg
     4861 cagcaatgac gattactcct tcatttccgt cgaagccatc catttctaca agcaattggt
     4921 tcaatgtttg ttcgcgttca tcatgtccgc cgcccatacc ggcaccacgt tgacgaccta
     4981 ccgcatcaat ttcatcaatg aaaatgatag ctggtgcgtt tttcttcgct gtttcaaaca
     5041 aatcacgaac acgacttgct ccaacaccga caaacatttc tacgaaatca gaacccgaga
     5101 tcgagtaaaa cggtactcca gcttctccgg caacagcttt tgctaataag gttttacctg
     5161 ttcctggagg tccttctaaa agtacacctg ccgggatacg ggcacctaat tcaacaaatc
     5221 ggcgaggatc tttcagaaat tcaacaactt caactagttc ttgtttttct tcttccgcac
     5281 ccgctacatc agaaaaacgt acgcgattag cttttttgtc tgcttctttg gcttttgatt
     5341 taccaaagtt catgacacgg ccgccaccgc cttgttgtcc catcatcatg taaaagaaaa
     5401 agatgatgat tacgattggc aagaagctaa gcaataggga aacccatata ccgctgcttg
     5461 attcttcttt tactgttgta gcaactttgt tttcttttgc cagttctgtt acttggctca
     5521 atgttgtatc atttggcaaa atgattgttg tgaaatgggt agtagtcgta tctgttgaac
     5581 ctaagatagc taacccaccg ctgttagcga cggtctgctg ttctttgtat tcaccagtga
     5641 tcttatatac accatttgca ggctgcactt caaattcttt gatcttgcct gcttgtagtt
     5701 gttctgtgaa ttttgagtac tcgatatctg acgatcgctg gccgttatta ccaaaaatga
     5761 aataaacgac cattaccatc gctaagatta cgaggacata atacaaggca tttttcatca
     5821 tgccgttgtt ctttttgttc atagttgccc tccctaagcg tcaatttaat ttaacagttt
     5881 tttatcaatc ctgaccattc tattgtacca taatttaatt gagatacagc attaatttga
     5941 ttgataaaca ctaggtttca atacaccgat gtacggaagg ttacgatatg cttctgcata
     6001 atccaagcca taaccgacca caaattcatt tggtacgttg aagccaacat aatctgcttc
     6061 gatatttact actcttcctt caggtttgtc aagtagtgta acaattttga ctgattttgc
     6121 tttgcggtat ttgaaaagat ccactaaata agcaagtgtt cttccgctgt caatgatatc
     6181 ttcaacgatc aacagatcgc gaccttctac attcgtatct aagtctttga cgatttttac
     6241 ttcccctgac gagactgttg cattcccgta gcttgaaaca tccatgaaat ccaattccaa
     6301 atacgtatcg atagaacgaa cgatatctgc catgaatggt accgctcctt ttaagacacc
     6361 tactactagg ggattggtgt tttggtaaat ttctgttaac tctttgccta gttctttgca
     6421 acgaacttgt atctcttctt gtgagatcaa aattctctca atatcctttt ccaacatcag
     6481 gttctccttc caattgcttc tttttgatat ttgtaaagaa gtatgtagtg tattttatca
     6541 gtttcttcac gaatactcaa atatgaaaag gcaaaaggta tcaagctata tatatttctt
     6601 ttggcatctg taatgatcca agcatgctgc ctttgtgaat taggtacttt ctgatcgata
     6661 aaatatctag atactttttt tgtgagattc tctgttaatt taatgcggtc tcctgctttt
     6721 cttttttcga catacagttg cacatcagca ggaatccaaa tgtcatgaga aaatagagac
     6781 catgaatctg ttgctttgat gtcccctgca ttttcaggtt tgaccagacc aatccattct
     6841 gtttcattca aatatattcc ttgttctgga atcagcaaca agcgctggtc ttctgtctgg
     6901 ctagttgctt gtttttcttt tttagagagt acaacaaaat gatactctct tttcagtatc
     6961 caattattgc caatactgag ttgccattgg ctttttttct gttgccactg gtctaaaatc
     7021 gactccattt gttgttcttt caaaataatt cctgtttttg agaatgcttt gtcgaaaaag
     7081 gagtaaaaaa aatagtatcg ttcagcatct gtcatttctt caatcatttc tgcagaaaat
     7141 cgaaattgtt cctcccactg ttcgacttcc ttttcgatca actgtcccat atatttttga
     7201 atgacttggt ctgcccattg gatctgttgc gaaaattgct ggaaatgtct caacgcctgt
     7261 gtattttctt gtttcaattg aggaactacc aaatgacgaa gccgatttct ctggatatct
     7321 aacaattggt ttgtctgatc ctcaaagtaa acaagctgcg attccgctgc ataagtatat
     7381 aggtcttctt tgctaaaact cagcaacgga cgaatcagtc tgcccgtagc aaatggttgt
     7441 acttctttga ttccagaaaa agtatttaac tgtcccccac gaacgatttt cattaacacc
     7501 gtctcgattt gatcatctcc gtgatgagca gtcatcaacg tgtcatattg tccttcttcc
     7561 atcacgcgag tgaattcttg ataacgaaag ttacgagctt ctgtttctat ggcggatttg
     7621 gctggatctt cccaaatact tacatataaa gggagattct tctcttcaca atatgagcga
     7681 agataggcag cttcttctgc tgattcttct cttaattggt gattgatgtg gacgatacct
     7741 aaagaaaaac cgatttggcg ttgcacttgt aaaagtaaat ggagcaaaac catcgaatca
     7801 acaccacctg ataccgctgc taaaattctc gatccttgtt gccagaatcc ttgttcattc
     7861 ccgtgccgaa taaatgactg ctgtaatagc ggtgcttttt tcccgccttt ttcaacgttc
     7921 atcctttcca caccctttct tcctaaaaaa aagagagcgg gaaaacgtct aaaacgacaa
     7981 ttaacctgcc ctctgttgat actatgaccc aaatagtcgc actatcatta tttgcggctt
     8041 tttagctgcg acgtccgcca cggccaccgc gctttccttc tgtgtttcgc ttcaatgaag
     8101 ataagcggtc atcgctatct ttcaaaaatg aactcatcaa tgaatcgaag tcttcttttt
     8161 gagctgaagg ttgactgcga gaaaaagatt ttttctgtgc tggacgattt cggttgtcac
     8221 ggggatcttt ttgttgatat tttttaggac ggctttcttc tccagattca gcaggttgtt
     8281 cctgcgcttt ccggatagat agtccgattt ttccatcatc atttactgaa ataactttaa
     8341 ctgttacttc atctcctaca cttaaaacat catggatgtc ttttacatag ccatttgaca
     8401 cttcgctaat atgaactaga cccgtttttc cagcacctag atcaataaac gcaccaaaat
     8461 ttgtgattcc tgatactttt ccttgcagtt ttgctcctac ctcgattgac ataaaaaaaa
     8521 tgttcctcct aattatttcc cttttttata ttcctgctta ttttgcagtt gtagaactag
     8581 ttgattgatc tgtttcattt gtcgagctgt ctgtatttga ttctaatata ggataaactt
     8641 tttcaccgtc ttttgagtaa aagaatttgc ttctggcaag tttagctaca tactcatcat
     8701 ctttcagcaa tgaaacatct tggtgcagct gatcaacgtc tgcgttgact tctttcattt
     8761 cagtatttgc ttcgactctc aattcgttca attgatgcat cctttgcatg tcatggaaaa
     8821 tctgcacacc tattatcgcg aaaatgacca aagcaccaac aaaaattgca gccagtctgc
     8881 gtcttcgaaa aatcagttga cgttgttgtt gctgaaattc agcatacttt ttctttgcat
     8941 attccgtatc tagcgcagcg attttattgc tttttttcgt cacttggatt cgctccaatc
     9001 tttttgattg tctttttcat tataccaata tcgtgaaagc ttgtctaatc tatttctcta
     9061 gtgtttctgt gcgattttca gaaataattt cgtacatttt ttgtgcatct tcttttttgg
     9121 ttgattcatg taattccgta attttcactt ccaacgtttt gttgccaaac tggactttca
     9181 aaatatcgcc tactttgaca tcactggaag atttcgccaa tttaccgttg atttgaattc
     9241 ttcctttatc agctacttct tttgctactg atcgtctttt gatgattcgg gaaattttta
     9301 aaaatttatc taatcgcata tcttattcct cactttttaa tttttttatt taatcgcagg
     9361 attttcttac caaaaggcaa cattagccat tctcgtactg taaacagacg aagacgaatc
     9421 actgcataaa tgaacacaga agccccgatc ccaactccta tcacgctgac aaaaaaagca
     9481 gtggaacgat gagttacagg accaaatact atattcaata caccataata cagcagcagt
     9541 actactgtca tacaaagaag gctgaacatc aacttccgtc caaaatgccg ttctttccaa
     9601 aaagcattta gctcttttgt ttcaattcga acaaaatacc aaagcgtcac acctaatcct
     9661 aaaagggtag acaggcttgc acctgctgtt cctaataaac cggtcagaaa agaagtagtc
     9721 aatcctttta ccaatagtcc ccatcctgcg ccttttaaag aagggcgaaa cgagttcttg
     9781 ctttgagcaa tactttgata agcttggatg actgcagtga aagcaatgga aaaaacaaat
     9841 aatacaagcg ctgcatttcc cgcataatct ttaaacaacg cataattgat ataagggagc
     9901 agcaaggcta atcccaaaga cgcagctaat gctaaagcgg tcgtcaatct aagatagatt
     9961 ttggctgtct gtaaaaactg acgatagatc cggttggtca aatgacgagt caacgcaggc
    10021 aggaatgtcg cacttaatgc agtggcaatc actaaaccta attgtactaa aggctgacct
    10081 cgatcataga ccccttttgc tatcttcgca ccgtattctg acagtccgta aacttccaaa
    10141 gcatttttta caaagaaaga gtcgatcagc tggaaaaaga taagcaatcc actataaatc
    10201 gaaaccagtc cgccttctac cagaaaacgc cggatcaagg gctttgacgg ctgtttgaac
    10261 aatggaaacc gtcggaagct taacgctcct ccatgaatct tttgttcata gtagtgaagg
    10321 atcccatatg cgcataaacc gccaaaaaca gctccactca ttgctgccgt ccctgtttgg
    10381 tacaccgtcc atccaagctt tctaaaagca aacgcactac agacaatcac aaaaacacga
    10441 acgaactgct caactacttg agaaacagca gttggttcca tcaagaatct tccttggaaa
    10501 ttccctcgat aaaaagatag accaggcatc agcaaaaagg taaaggaaac tacttggatc
    10561 agcggtttca attgtatgtc tcccatcatc caagcaatcc agctgctaaa tgcaaagaca
    10621 aacaaccaca aaaagacacc tgtccaaaat actaagggat aaagattttg caaagcttgc
    10681 tttcgctcga aaggattctt tctttctgca acgtactttg atatgaactg cggaagaccg
    10741 gataaagcta aagtcattgc tatcccataa attggataaa cttgctgata aacataaaaa
    10801 ccttcgtcgc cgactaagtt ttggagggga attcggtaaa gggcacttaa tacttttgct
    10861 atgaaagaag caatcgtcaa tacaaatgct ccttgcatga cgcgccgcat ttctttatga
    10921 tccaaatcat tgctccttcc tacgctgaca gatatttttg ctcacgcaac gctttgacaa
    10981 acttttggat ttcctgaagc catactgctt cttccatttg gttggggatc gtcaagcgta
    11041 tcaccatctg ttctttttca acgcctagac tggcttttag ttttgtcgct gtcagtgctt
    11101 cgaataactg ttccacacta tagcgttttg ttccaacttt acttagagta aagactatat
    11161 gcgcctcctg tttccttatc gtttctagga gcgctcgatc gccatccatt ttgatctgcc
    11221 caattgtcaa gagatgtgct acttcttctg gatattctcc aaaacggtcg agcagatcat
    11281 cttctagttc atctagcatt tcttgcgaat caagttcacg aattcgttta tagatctcga
    11341 ttttctgccg ttgatctgcc acgtatgttt caggtagata cgcatcgaca ccgaggtcga
    11401 tctcaacagt ggtcttctcc acttgactat tctttccttg tttacgagaa acagcttcgc
    11461 ttagcatttg agaatacata tcgaaaccga ctgcatcaat aaatccatgc tgctgagcac
    11521 ctaagagatt acctgcaccg cgaatggaaa gatcccgcat cgcaatcttg aatccagatc
    11581 ccagttctgt aaaatctttg attgcctgaa gacgtttttc actgacttcg ttaaggatct
    11641 tctgctgctc atacataaag taagcatatg cgacacggct gcttcttcct acccgccctc
    11701 gcaattggta taacgtggat aatcccatat aatcagcgtt ctcaacgaac aacgtatttg
    11761 cgttcgggat atctactcct gtttcaatga tggttgtagt gacaagaaca tcatattgac
    11821 cttcaataaa ttcaaaaagc gtattttcta attgcgcctc tgtcatttgc ccatgagcat
    11881 aaccgatccg tgcttccgga acgagttctt ggatttcttc tactttttgt tcgatcgttt
    11941 ctacccgatt atataaatag aatacttgtc cacctcgtcc catttctcga tggattgctt
    12001 cgcgaatagc cccaggattt ttttccataa catacgtttg gatcggataa cgattcgcag
    12061 gcggtgtttc gattactgaa agatcccgca cgcctaacat cgacatatgc aaagttctcg
    12121 gaatcggtgt tgcagtcaga gtcaaaacat ccacttgtgc acgtaactgt ttcaatcgtt
    12181 ccttatgttt tacaccaaaa cgttgttctt cgtcaatgat cagtagaccc aaatcgctaa
    12241 attcaatatc ttttgacaaa attcggtggg ttcctacaac aatatcaact tgacctgtac
    12301 gcagttgttc gatggtttct ttttgttgct ttcttgttct gaaacgactt aatagcccga
    12361 tatttacggg gaaaccttca aatctttcca gcatcgtttc atagtgctgc tgtgccaaga
    12421 tcgttgttgg aactaaaaag gctacttgtt tgctttcctt tatcgcttta aaggccgctc
    12481 gaagcgctac ttctgttttc ccataaccaa catcacctac gagtagtcga tccattggtt
    12541 tttctttttc catatcccgt ttgatctccg ctgcacttct caactggtca tcagtttcag
    12601 agtaggggaa ggcattttcg aattcttttt ggtaggcgtc atcaggtcca aaagcatatc
    12661 ctttttctga ctctcttgcg gcatataatt tgattagatc gtcagcgata tcctcgattt
    12721 ttgaagagac ttttcgcttg gttttcgtcc attcacttcc gcctagctta ttgatgcgag
    12781 gcgctttggc ttcagaggcg acatattttt ggatcagatt cagttgagta acaggaataa
    12841 acagtttgtc gtcgttttga tacaaaatag tcatatagtc ttggtgaacg ccatctactt
    12901 ctagcgtttc catcccaatg tatttcccga taccatgatt ggcatggaca acgtaatctc
    12961 ctgcttttaa ctcattatag cttttcaatc gctctgcgtt tgttactgtt tgacgtctcg
    13021 tttgtttttt cgtcgttttt tggaaaattt ctttttctgt gatagctact attttttctt
    13081 gaggaagttc aaaaccagcc tgcaaagctc cttcaactaa ttgtacctgt cctctgatca
    13141 atgcattttt ttctgtttct actactaata tgtcttcatc tcgaagcatt tgttctgctt
    13201 tgcgtattct gtcctttgtc ggaataaaga tcacaacagt ctgtttttgc ttgcgccaac
    13261 ggtccatttc tgttttcagc aatggcattt gtccgaagaa ctgttgcatc gtccgatatt
    13321 gaaaattatg gattgcttgg aaacgaagat ttcccatccc tttttggaag agtgagaaaa
    13381 aggttgtggt gaacttttcc ttctgcacga ttttttgtat atctgctgaa aatgtctgct
    13441 cagaaaacac ccgcaattcg ctgatttttt gagtctgcca ttctgccgct tccctttcga
    13501 tttcccgatt tgtttccatg attcgctgat aatcatcaac gactagtaaa ctatttgaag
    13561 ggaaataatc caagatcgtc acagattctt ggtaaagaag atctgagtag aattttgctt
    13621 cttctgtcgg gacacctgct tgccagcttg aagtcagctg accgaagtaa tcttgcaaaa
    13681 actcgcggtc tgcttcttct gtggtcgcag caagccgttt ttctagcatt ttttgcattt
    13741 gctctattcc atgttctaga tcctctggtc cgtagacttg ttcactcgtt ggggaaaccc
    13801 agatttcttc cgttttttcg attgagcgtt gtgtttctgc ttcaaaatac cgcatagaat
    13861 ctatctctac atcaaatagt tctacacgaa caggataggt tgtcgttaac gggtaaatat
    13921 cgataatgct tcctcgaata ctgaattctc ccggttttgc gaccatctct tctcgtacat
    13981 agcccatcaa agtcaattgg cgaggaagat tttccacgtc tatctcatca ccaatatgcc
    14041 aattcaattg cgcctgtagc caagttttct tattcggcag tcgtttgtgc aaagatgcga
    14101 ctggcaacaa atagatacct gctttttttt cttgaagtgc gttaagcgtt gcaactctct
    14161 cgcctcgcgc ttctggagaa gaaaaggcca tttcagcaga aagcacttca tccactggaa
    14221 ataaatggat ctgatcttgc ggaatcacat gttgcagatc ttctgctaac tgattcgcat
    14281 aatacaaatt tggcatcaga ataatcatgt ttttatttgt tttcttaaac gctcgagcaa
    14341 atagaagtgt tttcgctgag cccgctaatc ctgtgattag ttgtctaggc attttttctt
    14401 ctaaattgct gacccattct tttacttgcg gatcttttcc gactaattga ataatatcca
    14461 ttccttttcc tccttcctca attgaatcga ttcatcgcat ccacgaacga atgcccttct
    14521 atgagatatt cgactgcttt aacagattga cacatgcttt cttctatcaa aggctgattt
    14581 tctttgctga aaggactaag cacatgctgg actactgttt ttttcccttc tggcctgccg
    14641 attcccacct tgattcgatc aaagacattc gtattcaaat gggaaataat acttttgata
    14701 ccgttatgcc cgccggcact tcccttttga cggagccgga tttttcccac tgccagatcc
    14761 aaatcatcgt agattacgac taattcctct ggataaatcc caaaataagt cattagtggg
    14821 ccgactgcac gaccagattc attcatgaat gtttgtggtt tgactaaaag gatcttttct
    14881 ccattatgaa aaaattcggc aacttctgct tcgaacggat tttttttgaa agtagcttga
    14941 tgctcgcgtg caattttatc cacgaccata aagccgatat tgtgttttgt atattggtat
    15001 ttggtacctg ggtttcctaa cccgacgatc attttcattt ttgttttcca cctaattcta
    15061 aaaagcagca caaaaggctg gactgctaat tagcggtcca gtccatcgag cttttttctt
    15121 ttttatactt gtcaatgcat agtataacac aaaacaaggc gtttcggcta aaagagaatc
    15181 gttaataaat gataaagaaa ttaaaaattt cttcaaagtt taatgaaata attgatatat
    15241 aaaaatagtg aaataacgca catgtaagct tttacatata atacaacctt gttatctgtt
    15301 atattttata gccaaatagc gtgacatggg gcttgagaaa tgttagcata agcatgggaa
    15361 aaaacaaatc aatggaagga ttgatactaa atgactgcag ctgcagaaaa aaaagatcat
    15421 caaaaagtta ttcttgttgg agacggcgcc gtaggttcta gctatgcctt tgctctagtt
    15481 actcaaaata tcgctcaaga agtaggtatt gtggatatca atactgctaa aactgaagga
    15541 gacgcaattg acttgtctca cgctttggca tttacttcac ctaaaaaaat ctattctgct
    15601 acttacgcag acgcacatga tgctgactta gttgttatta cagctggcgc accacaaaaa
    15661 ccaggtgaaa ctcgtttaga cttagtaaac aaaaacctaa aaatcaaccg cgatgttgtc
    15721 acacaaatcg ttgaatcagg atttaacggt atctttttag ttgccgctaa cccagtagat
    15781 attttgactt actcaacttg gaaattctca ggtttcccta aagaacgcgt aatcggttca
    15841 ggtacctctc ttgactcagc tcgtttccgt caagcacttg cggaattagt tgacgttgat
    15901 gcacgtaacg tccatgctta catcttaggt gaacacggag attcagaatt cccagtttgg
    15961 tcacatgcaa atgttgccgg cttgcaaatc tatgaatggg taaaaaacaa cccagaaatc
    16021 gatgaagaag ctatggttaa cctattcttt ggcgtacgtg acgctgctta cacaattatc
    16081 gagaaaaaag gcgctacttt ctatggtatc gcagtagcat tagcacgtat cactcgtgcc
    16141 atcttagatg atgaaaatgc tgttcttcct ttatcagtat tcatgaatgg cgaatatgga
    16201 ttgaacgaca tctacattgg tgcacctgct gttatcaacc gtcaaggtat ccaaaaagta
    16261 atcgaaattc ctttaagtga cagcgagcaa gaccgtatgg ctgcttctgc taagcaatta
    16321 aaagaaattc tagatgaagc ttttgctaaa ctagacgctg aataatcttt gaacatgacg
    16381 gaaaacatct attcggtgtt ttccgttttt ttattttatc acccttatgg tttctaaatt
    16441 ttttcataaa gtagagataa ccttcgtctt ttcctctaaa ttatgctatc atgagaccgt
    16501 tccaccctaa acttttactt aaggagttgt cgatatgaca agatcttcgc atcgaaaaaa
    16561 atcgaaacat gttgctttgc tttcagttct tggtgttctc ttagtgctga tcagctttta
    16621 tacctatcgc agtacatact acacaaagca ttttttgccg aatacagaaa taaatggaat
    16681 aaatgtcagc aatctaacag tcgaaaaagc aaatgaaaaa ttaaaagaag cttattctga
    16741 taaaaaactg gctattaaag aagatggaaa agtctggcag gaagtaccaa aatccgagct
    16801 cggctacaaa gatgatttca cttcggagct ttctccgatc ctaaatgaac aaaacggatg
    16861 gacttgggga atgacttatg tctcagcggc agaaaaacaa gaaatagatc ctgtcagtca
    16921 aaaccaccaa aaactagaca ctaccgttca gacattgaca actaagctga ctgatttgaa
    16981 caaagaccgg acacctacta ctgatgcaac gatcgaaaaa gcaggtgact ctttcgttat
    17041 caagcctgaa gtcaatggaa atacgatcga cgtcgatgct gcggtcaaac aattaaaaag
    17101 tgcggtaaac tctggtaaag atacaattga attgactgaa ttcaaagaaa aaccaaaagt
    17161 aacatctgaa gacagctcac tgaaagaaca actcgcatcc atgaatgcta tcgcaaatgt
    17221 aaaagctact tacagtataa acggtgagac tttccagatc ccatcaagtg atattatgag
    17281 ttggctgacc tacaatgatg gaaaagtcga tttagataca gaacaagtac gtcaatatgt
    17341 aacagattta ggcacaaagt ataacacaag tacgaatgac acaaaattta aaagtacaaa
    17401 aagaggagaa gttacggtcc cagttggcac ttacagttgg acgatccaaa cagacagtga
    17461 gacagaagca ttgaaaaaag cgattctggc aggccaagat tttactcgtt cacccattgt
    17521 gcaaggtggc acaaccgctg atcatccatt gatcgaagat acgtatatcg aagttgatct
    17581 ggagaaccag catatgtggt attacaaaga cggaaaagtg gcccttgaaa cagatatcgt
    17641 ttccggaaag ccaactacac ctacacctgc tggagtcttc tatgtttgga ataaagaaga
    17701 agatgcaact ttaaaaggaa caaatgacga tggaacacct tacgagagtc cggtaaacta
    17761 ctggatgccg attgactgga caggtgttgg tatccacgat tcagactggc aacctgaata
    17821 cggtggagac ttatggaaaa cccgcggttc acacggctgc atcaacaccc caccaagtgt
    17881 aatgaaggaa ttattcggga tggtcgaaaa aggaacgcct gtattggtct tctaacaaaa
    17941 ataatatata aaaagaaagc acccgtacga ttggtacagg tgctttcttt ttattatcta
    18001 acaatgtgct acttacattt cagcagcagt aaagacttct gaaacatcat catcgtcttc
    18061 tagcttatct actagacgtt ccaattgctc tttttgttcc tcatttaaat caatcgtcgt
    18121 ttgtggaatc atcgtcaatt ctgcttgcgc caaagtgaac tctttttcca actcatctcg
    18181 tacagcagca aaatcttctg gtgcagtata aatctcgaat acttcaggag aagtttgcag
    18241 atcttctgcc cccgcctcta atacatcctc aaacatcgtc tcttcatcaa cagtcaaccc
    18301 atcgcgttca atagcgatat atcctttgcg gtcaaacaag taactgactg aacccgtttc
    18361 tcccagtgat ccaccgtttc gagtaaaagc tactcggaca tttgtcgctg tccgattacg
    18421 gttatctgtc aatgcatgga ctaagattcc tactccaccc ggaccatatc cttcatacgt
    18481 gatttcatcg taattcgttt catctacggc actcgtagcc tttttaatcg cccgttccac
    18541 attgtcgtta ggcatatttg cagcttttgc tttgtccaca acaagccgca aagctggatt
    18601 catagatgga tcaggaccgc ctgctttagc tgccatataa atttcacgag aaagtttctg
    18661 aaagactttc cctcgttttg catcttgggc attttttctt ccttggatat tatgccattt
    18721 actatgtcct gacatgattt ttcctccctt gttcttttga gaatacactt ctattctagt
    18781 actatttcac aaaaaaacaa agccacagcc aatctataaa cgcttcttga atgccgcaaa
    18841 aagcacacat aatatcacag cagtcagagc accgatcgaa tccaacatga catcttggaa
    18901 cataggtgtt cgtccaccgg tcatcatctg atggaattcg tccaaacctg cgtaccctgt
    18961 tgctgaaagc caagcaagga tcgctgtcag ccaccaaatt tttagcttgg ggaaaacacc
    19021 taaaaacaag ctgcctccca aaataaaata ggtaccgaaa tgtgcgccct tccttaaaaa
    19081 gaactctaaa aatttggcgt agcccagatg gtcgatactc accatacttc caccataatt
    19141 aaaacgtata cccgctaatg tgtctttaaa tggctgatta ggcagccagc tttctaatcg
    19201 cgaaacttgt gattgctgtc cgtaagtttg agaagaactg taaaataaga ttataacgac
    19261 tatcagtgcg attactaaat aaatatttcc gtttttcatt tgtttttttg aagaattcat
    19321 aagtcacctc tgtattttat cttagacttt ttttgaagaa acaacaatca ttttcataga
    19381 gacttcttcc ataaaaaagt gctatactta attttgtatt acaatatgaa gggagttttt
    19441 tcatgagtta ttcattaaat tggaatctag attctatttt ttccggaggc agtcattctg
    19501 atgctttgaa ccaacggatg aagcaattgg aagaccaaat gaacgagtat tatcaccgcg
    19561 taacaaaatg gtcacctagt tctgacaatg cagagcagtt aaacgctatt cttcaattgc
    19621 aagaaacgat tacgaatggt tttacccaat gcagcagcta tattactgca ttgctttctg
    19681 ccaatgtcaa tgattcagat gcaaaggtct tatcaggcaa gctttacgca atgctgcctc
    19741 gtctgcaatc agccgaaact gtattgtcaa agaaatttgc agaaatatct gacaatgatt
    19801 ggaatcagat gctttctcaa tcttcgtttg aaacaattgc ttttcgttta aacgagattc
    19861 gtcgtgatgg ctcacaatta ttatcagaag ctgaagaaaa cattataaat acgctttctt
    19921 tagatggtct aaatgcttgg agcagtcatt atgatacgat tgtagccagc atttcgattc
    19981 ccttcgaaca agatggacaa gtagtcgaat tatctgctgg acaagccttc aataagatga
    20041 tgggcgatcc agatccaaaa gtcagagaaa cacttttcgc agcatgggaa gaagcctgga
    20101 aagaaaaggc acccctcttc acggatactt tgaatcattt agatggtttt agactttctg
    20161 actatgaact tcatggtgtc acagattttc tacaaaaacc attagagtac aatcggttga
    20221 agaaagaaac attgtctgtc atgtgggata caatccagaa aaacaaacaa ccccttgtta
    20281 attacttgac tagaaaagct aatcttttcg gtaaagaaaa aatggaatgg caagatcaag
    20341 atgcacctat tattttaggc gatttgaaag aaaaaacctt tagttttgac gaagcagcag
    20401 catttattat cgaaaacttt aacaaattca gtccaaaaat ggctaaattt gcccaatctg
    20461 cttttgaaaa gagctggatc gaagcagaag atcgtcctgg gaaacgtcct ggtggttatt
    20521 gtactgagtt accagaaaca aaagaatcaa ggatctttat gacctacagt aattctgtta
    20581 atgaggttgc gacacttgct catgaactag gacatgcttt ccatagcagc acgatgtggg
    20641 atttaccttc tttaaatcgc gaatatgcca tgaatgtcgc agaaacagca agtacattcg
    20701 cagaactgat cgtagccgat gctacattaa aagtcgcaaa aacaaaagaa gaaaaaatca
    20761 atttgctaga tacaaaactg caaaatgctt tagctatgtt catgaatatc cattcccgat
    20821 tcatttttga aaatcgattc tatgaagcac ggcaagaagg attagtctca gaagataaga
    20881 tcacagagat gatggttgag gcgcaaaaag aaggctatca aggagcttta gctacttacc
    20941 atccatattt ctgggctgca aaattgcatt tctttattga tgacgtaccg ttttataact
    21001 tcccatacac atttggctac ctctttagtt tgggcatcta tgcttacgcc aaccaaaagg
    21061 gagcaaattt tgaagaagaa tatatccatt tactacgcga tactgcctca atgacgacgg
    21121 aagatcttgc gaagaaacat ttgaatgtcg atcttaccca accagatttt tggcaagcag
    21181 gtatcgacat ggtgactgaa gatatccaaa cgttcatgga attgacagaa gaatttatct
    21241 gatttctatt ttatcacaat aaaaaa
//
LOCUS       DAFEEZ010000047        20716 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000047
VERSION     DAFEEZ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20716
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.049"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            165..359
                     /locus_tag="LP245_001894"
     CDS             165..359
                     /locus_tag="LP245_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519813.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            628..927
                     /locus_tag="LP245_001895"
     CDS             628..927
                     /locus_tag="LP245_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519814.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1024..1458)
                     /locus_tag="LP245_001896"
     CDS             complement(1024..1458)
                     /locus_tag="LP245_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1519815.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1690..2400)
                     /locus_tag="LP245_001897"
     CDS             complement(1690..2400)
                     /locus_tag="LP245_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBL1519816.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2390..3250)
                     /locus_tag="LP245_001898"
     CDS             complement(2390..3250)
                     /locus_tag="LP245_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBL1519817.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3255..3893)
                     /locus_tag="LP245_001899"
     CDS             complement(3255..3893)
                     /locus_tag="LP245_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBL1519818.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3908..4207)
                     /locus_tag="LP245_001900"
     CDS             complement(3908..4207)
                     /locus_tag="LP245_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1519819.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4250..5734)
                     /locus_tag="LP245_001901"
     CDS             complement(4250..5734)
                     /locus_tag="LP245_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBL1519820.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5754..6215)
                     /locus_tag="LP245_001902"
     CDS             complement(5754..6215)
                     /locus_tag="LP245_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1519821.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6233..7300)
                     /gene="ulaG"
                     /locus_tag="LP245_001903"
     CDS             complement(6233..7300)
                     /gene="ulaG"
                     /locus_tag="LP245_001903"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBL1519822.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7518..8288
                     /locus_tag="LP245_001904"
     CDS             7518..8288
                     /locus_tag="LP245_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL1519823.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8561..9388)
                     /locus_tag="LP245_001905"
     CDS             complement(8561..9388)
                     /locus_tag="LP245_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1519824.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9956..11191
                     /locus_tag="LP245_001906"
     CDS             9956..11191
                     /locus_tag="LP245_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBL1519825.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12190..12450)
                     /locus_tag="LP245_001907"
     CDS             complement(12190..12450)
                     /locus_tag="LP245_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBL1519826.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12477..13778)
                     /locus_tag="LP245_001908"
     CDS             complement(12477..13778)
                     /locus_tag="LP245_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1519827.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14070..14528)
                     /locus_tag="LP245_001909"
     CDS             complement(14070..14528)
                     /locus_tag="LP245_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1519828.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14541..15872)
                     /locus_tag="LP245_001910"
     CDS             complement(14541..15872)
                     /locus_tag="LP245_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBL1519829.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15883..17325)
                     /locus_tag="LP245_001911"
     CDS             complement(15883..17325)
                     /locus_tag="LP245_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1519830.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17312..18076)
                     /locus_tag="LP245_001912"
     CDS             complement(17312..18076)
                     /locus_tag="LP245_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBL1519831.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18180..19055)
                     /locus_tag="LP245_001913"
     CDS             complement(18180..19055)
                     /locus_tag="LP245_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1519832.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19310..19394)
                     /locus_tag="LP245_001914"
     tRNA            complement(19310..19394)
                     /locus_tag="LP245_001914"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19358..19360),aa:Leu,seq:caa)
     gene            complement(19412..19483)
                     /locus_tag="LP245_001915"
     tRNA            complement(19412..19483)
                     /locus_tag="LP245_001915"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19449..19451),aa:Gln,seq:ttg)
     gene            complement(19493..19565)
                     /locus_tag="LP245_001916"
     tRNA            complement(19493..19565)
                     /locus_tag="LP245_001916"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19530..19532),aa:His,seq:gtg)
     gene            complement(19627..19711)
                     /locus_tag="LP245_001917"
     tRNA            complement(19627..19711)
                     /locus_tag="LP245_001917"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19675..19677),aa:Leu,seq:caa)
     gene            complement(19732..19802)
                     /locus_tag="LP245_001918"
     tRNA            complement(19732..19802)
                     /locus_tag="LP245_001918"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19768..19770),aa:Cys,seq:gca)
     gene            complement(19848..19919)
                     /locus_tag="LP245_001919"
     tRNA            complement(19848..19919)
                     /locus_tag="LP245_001919"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19885..19887),aa:Gln,seq:ttg)
     gene            complement(19931..20003)
                     /locus_tag="LP245_001920"
     tRNA            complement(19931..20003)
                     /locus_tag="LP245_001920"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19968..19970),aa:His,seq:gtg)
     gene            complement(20006..20079)
                     /locus_tag="LP245_001921"
     tRNA            complement(20006..20079)
                     /locus_tag="LP245_001921"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20045..20047),aa:Trp,seq:cca)
     gene            complement(20086..20166)
                     /locus_tag="LP245_001922"
     tRNA            complement(20086..20166)
                     /locus_tag="LP245_001922"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20130..20132),aa:Tyr,seq:gta)
     gene            complement(20168..20243)
                     /locus_tag="LP245_001923"
     tRNA            complement(20168..20243)
                     /locus_tag="LP245_001923"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20208..20210),aa:Phe,seq:gaa)
     gene            complement(20279..20351)
                     /locus_tag="LP245_001924"
     tRNA            complement(20279..20351)
                     /locus_tag="LP245_001924"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20316..20318),aa:Asp,seq:gtc)
     gene            complement(20361..20433)
                     /locus_tag="LP245_001925"
     tRNA            complement(20361..20433)
                     /locus_tag="LP245_001925"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20398..20400),aa:Val,seq:tac)
     gene            complement(20449..20520)
                     /locus_tag="LP245_001926"
     tRNA            complement(20449..20520)
                     /locus_tag="LP245_001926"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20485..20487),aa:Glu,seq:ttc)
     gene            complement(20535..20624)
                     /locus_tag="LP245_001927"
     tRNA            complement(20535..20624)
                     /locus_tag="LP245_001927"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20588..20590),aa:Ser,seq:gga)
BASE COUNT         6546 a         4335 c         3286 g         6549 t
ORIGIN      
        1 gaacaatagc cttttattat atatattatt caaattagtt atatcgagtg aaaaaaactt
       61 tcaaattgat tctttttatt tatcataaag atatagatac ataatcattt tcacttacat
      121 atatttgaat attaactaaa aacagcaaga aagaagagga tcaaatgtat tatgtagaag
      181 taaaaacaaa aggcgtcaaa aacaaacaat atgtgaaagg tatcagtaac gaatatcctt
      241 tacttggttc atggaaagaa gctgctcctt tttccaaacc atgtgccata aaaataaaga
      301 acgagctaga aaaagaactg acttgtggta aagctgttgt agatatcatc gaaaagtaaa
      361 tccaatgtat agaaaggaag atcacacatg aaaagcgacg tacaaattgc taagattata
      421 gaattagaag aagaagacgc agtgttgaca attgaaaaaa aataaatgtt tgtataccat
      481 atgattattt caatatgtat cctggaattg gagatctcgt agagctatat caagatgaat
      541 caaatatact tgtcattcat catgaaatat agagacttat aaaattgttt atttttataa
      601 tgtatcagta tagaaaggaa ataaaacatg gattatactg ttgaatttga cagtgaacta
      661 cttaagcaat ttccacaaga agaacatttc atgtataaag aagcaatttc ccacaaagtg
      721 acagagtatt tggagcataa tttttttcgt ataaagccag tgcgtactcg ttcggcaaaa
      781 ggaatatacg agatgaaagt caaaattaat aaaaaaaatt atcgcatagc atttgcttta
      841 aaaaaaaatc atgtgttcat tttttatatt agttcgaatt tgcaaaaaat tgtatttgat
      901 aaagaggtga gtaaaaaaat aaaatagctg agcattggag gatagattga gtgatactaa
      961 gtctatcctc ttgtttttct aaagaactaa gctagaattt tttcttttgt acgttattat
     1021 atgttatttg tcattaccaa aaagcacctt ttttcttcta gtatctatga cataagaaat
     1081 accacccatt tcctttactt gaacaaatcc tactgattca taaaattttt ttgttttctc
     1141 agtatcatct gtcaataatt cgatttggac tggtccataa ctagtgatct tctccaaagc
     1201 ttcattcaaa agcactttgc ctattccttg gcgctgatac ctcggatgaa tgaggatatc
     1261 ttgaataaat gcgatcgtcg caaaatcagt gatccaacga acgattccga taatcttccc
     1321 ttccccatta cgctttatca gagattcaga ttgttcaaat gctctagcta accttgcagt
     1381 gtcttttgtg taattcgtcc aaccaacgct cttatataat tcagaaatct catcgatcat
     1441 aagggaatca atattcattt ttttcttcct ttcttataca attctccctc taataataca
     1501 gttctttgac tatttaatct atcacatata actctcctgt aaagattctc tcgattcctt
     1561 aaaattcctc tttcctttta gaatgcatac tttttgataa ataaaaaggt tgtgataaat
     1621 tttcttcaca acctctgttt ctctctatca agtgttatct tttaattttc tacccttacc
     1681 ctagcatctc tattgcccgt agtatgcata ctttccatgt ttgcgaaaat aatgtttatc
     1741 tagtaaatat tgcgggattt cacatatatt ggggttgatc agctcgtttt ctttggccat
     1801 cagacaaatt tcatctaaga tcaaactgtt ttctactgct ttcataggtg aatcccccca
     1861 tgtgaacggt ccatgtccat agacaagtac tccagggact tcgtttggat ctaattttct
     1921 ttccttaaac gtctcgacaa tcacattccc tgtatgaact tcgtaagctt ctcttacttc
     1981 ttctttcgtt aattggcgtg tacaaggaac cttaccataa aaagcatcag catgagtcgt
     2041 gccataagct ggcaaatcgc gtcctgcttg cgcccacatg acggagtgcg tggaatgagt
     2101 atgagtaata gcagttatat cttcaaaagt ttgatacaaa acaacatgtg tggggagatc
     2161 tgaagatggt tttaagctat cttcttctat tatatttccc gacaaatctg ttaccaccat
     2221 ttgatctgct tgcatgcatt catatctgac accgcttggc ttaatgacga tgactcctag
     2281 ctcacggtcc acttcactca cattgcccca agtcaatttg actaatccgt atcgcggcaa
     2341 tgccagattt gcttcaagga cacgttgctt cattgctgca attttttctt cacaagacat
     2401 catagccagc ctccttcaat ttagaactta agtagtcttt tgcctgctgg atttctcttc
     2461 gaaagtcttg gcttttttca ctccacattt caatcagaaa tgttccatca taatctagac
     2521 gtttcaaatg tcttaataat ccaagaaaat caacacaacc gctaccaaaa ggaacatcac
     2581 gaaactggcc tgaatattct tttgttacag ggtaagtatc ttttaagtgg atagcagtga
     2641 tataatcgat ccctttctca agttctcgag ccggattatt ttccggccat gcggacaaat
     2701 tgcctaggtc tggatatact tgtagaaaag gtgaatgaat ctgttctttg atttctaaaa
     2761 attttgaaat ggagttcata aatggatcat ccatgatttc cacggaaaga atgatgccat
     2821 atttagaagc ttcctttacg ctttctttta ttccttcgat aaagtcttct ctggaattca
     2881 ttgatttctc ttcataataa acatcgtatc cagctatttg gattactttg acgcttagat
     2941 tatgcgccaa atggattgct tttttcatta gttgtttcgc tgcttttttc ttttctggat
     3001 cagcagaacc aaacggaaat cgccgatgcg cacttaaaca aatcgaatgg atacgtacac
     3061 cggagctgaa catctcttct ctcagctcag ctatcttttc ttcagaccaa tctaatcgtg
     3121 ctaaccgctc atccgtctca tcaatcgaca tctcgataaa atcgaagtcc atttctttta
     3181 caagggaaaa acgttctttc catgaaatat ctttgggtaa cgctttttca taaatcccaa
     3241 tttgagccat ttccttaccc ccagatacga atgatctcat ctttgaagtt ttgtgcggcc
     3301 ttcatcggat catttgctgc tgtaatacca cgaccagtga taaaggtata cacatcgatc
     3361 ccttcaaata agtgtaatgt gtgtggattt aatccaccag ttacagaaac attaaagcct
     3421 agttcaatca gttttttgat cttcgataaa tctttttcac cccaagtttc accagataac
     3481 agcgcatcac ggctttgatg gtagattacc tgccggatac cgatgttatg ccaatccatg
     3541 gcttgttcaa aagtccaatt gccgtagagt tctacttgca attcacctat ttctttttgt
     3601 gctgcctcca tagttggaat cgttgcacaa caaatgactg tcatccagtc tgctcctgct
     3661 tttgcaacat tactcgccac tgttcctcca gcgtctgcac atttcgtatc agcgactagt
     3721 tttttatctg ggaacatact gcgaatacag cgaatcgctt tttgtccttc ctgtaagcaa
     3781 agaattgtgc ccacttcaat aatatctact acatcaccaa ctttcataac atctcctaat
     3841 gcatgttcta agtcattgtg atctaacgca atttgcaaat tcggcctgct catcttagtt
     3901 ccttccttta cttgtttttt tggtaccact ttgtttcagc aaatttttca ctgatttctt
     3961 tgactgacat cacatttttg ataccgataa ctgtaactcc ttttttctct gcctgagtaa
     4021 acatattcaa aaaattgact ggcgtaaaaa ctacatcgta ttggccagct gaactttttc
     4081 cctctgaaat ggcacaatga tggattttgg taattggtac gtttagttct ttcattgctt
     4141 tttccacact tctcatcatc atcaagcttg ttcctgatcc atttgcacac gatactaaaa
     4201 ttctcatctt aatccctcca ttatgagtgt tgtctaatca gattttcttt tatactctct
     4261 gcttttctgc atatgtgtca tagtcttcta caatcaaaaa ataaccatca ggatttttcc
     4321 gatattgtaa ctgcggaata gccaataaac caatgacaac tacggcaatt ccagcataac
     4381 ctaggacttt catgattact gtaaacaatg gccaagctgt tgcccagtcg aacatcccga
     4441 tataaccacc gtatgttgac atcccaatcc atgtagcgaa taatgctgaa ccgcctactt
     4501 gtatgattcc tgaaagaaac gggaacaggc aagcggcttt gaatccacct cggttattgg
     4561 cataaactgc tataacggca ttatcaaaga acaacggaat gaaaccggct atgacgatcg
     4621 ttggtgattt caataaaatc agtaaaccaa tcatcaaaaa ctgtcccaaa gcaccaaaca
     4681 agaacccaat cgttaccgca tttggcgaac caaagccaaa agtagcagct acgtcaattc
     4741 ctggaacagc tcctggtaaa atcgtgtttg agattccttg gaaagattga gttagttcat
     4801 cgacgaatgt ccgaacacct aattgcaaga tcgccagata taccgcaaaa tttaaagaag
     4861 tcgtcataat gtagaataag aaactctgcc cttcttgcat gaattgcgct tgaatcaaat
     4921 aatctttgcc tagtacaatc agaatgatcc caaagaaaaa tagcatgagt aacgaagtag
     4981 caaccatatt ctcattgaaa atcgacaaga atcctggtaa tttgatatct tcaatttttt
     5041 tgtcttgctt gattgatcta tttttctttt catcccgctt tttcatccac tcagctaatt
     5101 ttgcaaatat aaagattccg aacatttgct gatgtgccac tgcaaatccg gcaccttctg
     5161 tcaattcctg cgtgattcct actgttaagt tagaagctac tgtccaataa caacctaaaa
     5221 tcagtcccat aaaaatcaat gcttgtatcc tacctagatc aggaaagcaa aacagtaaaa
     5281 tccaaaaagc ggtagctgct tgttgaacct gaacgtttcc ggtagtgaaa acggaacgca
     5341 gtttcgtata tttctgaaaa cggactaata agatatttaa aacaaatgca atcagtaata
     5401 aaatcatcac atctccaaag gtacggccaa atgtctccat taatccagca tccacagcat
     5461 tttgtccaaa ataaggatct gtaaccatgg catccaaatt gaaccgttcc tttagtccaa
     5521 ccaagattgg ccgaaaatta ttgaccaaac caccagagcc aacagtcaaa ataaagtaac
     5581 cgaccgttgc ctttaagaat ccagcgatgc attcatgaag cgggcgtttc agcaaaatat
     5641 agcctaataa cacgataaaa ccaatcaggt atgctggctg cgtcaagata tttgttgcaa
     5701 aatacgtcca aatgcttaac aaaaattccc ccatcttttt tctcctctat caattaatta
     5761 tattctgcca tcacaacttg gtaatcatcg atggagttcg tagagatgag acgctcaacc
     5821 aatccatctg tcattaataa ttcggataat ttttggatat tttctagatg ttcttctgga
     5881 tcttttgctg cgagtgtaaa aaacaaacta gccgttttct cctcattctc cccttcactt
     5941 tcaaaacgga ttggctgttt caacttggta aatgaaatag ctgttccaaa aacaccatca
     6001 cttttttctg aagaatgcgg cattgctact tgaggtgcga tcacaatata aggaccgtat
     6061 ttttctacac aatggatgat ctcctccaca tacgtttcat caataatttc cttatcgatc
     6121 aatacaagac agctttcggc gatagcttca cgccaatccg tgatttcttt atctgggtaa
     6181 tgaatcaatt gatggtcaaa aaagtatttc agcaagaaac tccccttctt tcttataaaa
     6241 acgacggaaa cggtgtatca ttttcaatcg agaagacatc ttcaaatcct cgataaaaat
     6301 taaactcaag atcatctttg tttgtcggat agatgaattt cccgcctact tgccagatat
     6361 aaggtttaaa tccatacttc aggcgatcct ttttgaattt ccaaatttca gtgatctctt
     6421 ttggatcagc cataaaatta gaccaaatat cgtagtggac aggaatcact acttttgcat
     6481 tcaatgactc cgccatgcgc agcatatcaa cagaagtaac tttgtctgtt atccctcgtg
     6541 ggttttcacc ataggcccct aaacagacat cgattttgtg ttcattacca tgtttggcaa
     6601 ataaattgga gtaatgtgaa tctcctgcat gataaagatt ccctcctgat gtttcgaata
     6661 aatagtttac tgcaatttga tccatctcct gaggcatttt tccttttaat acctcttctg
     6721 gatcttcaca agtgaccaac gctgtccgat caaacgcttc taaagctact acattgatgt
     6781 ctttgatttt gactgcatca cctggcttta ctgtaatcgt tttttcttca ggaattcccc
     6841 atttttgcca cgtgcgaacc acttcttttg gcccaatgaa tgttgcttca ggacaatttt
     6901 gatgaactgc tgcggctgta tggatatcta gatgatcgga atggatatgt gtaacgatta
     6961 aagcgtctac attttttatc gcaaaaggat cgattacgaa aggctgagta cgtaaattag
     7021 gctgcatatt ttgaacgcca ctcatacgca tcatctgatg gccttttttc atcatgccat
     7081 tcccatgact acgttttccc gtcccacacc atagatcaca taaaatattc gttccttcat
     7141 gacttttcag ccaaattccc gtacagccca gccaccacat agcaaaagtt ccaggatcca
     7201 ctacttctgt ttcgatttct tcattcaagt atgtgcccca ctcaggaaat gtttctacta
     7261 accacttttc ttttgttact tcattgacag ttttactcat ttgcttgctc cccccatatc
     7321 gttgttccaa cttacaagta aatattaatg tgtatcagca tccatgaaaa cccttttata
     7381 tgaccgtttg ttttttatat gattttcttt cagtaatcaa tgattgtttc agtataataa
     7441 agacagatat gaatgtttaa atgaacaact agtcaaataa atccatggat caagatgtcc
     7501 ctcaggaggc aaaagtcatg aaaaactcac ttgtcaatat tgaaaaacgt caaaaagaaa
     7561 ttttggaact gcttcagcag actgaacaac tatcaacttt cgaattagct gaatcccttg
     7621 atgtatctat tagtacgata cgaagagatt taaatttatt agaagaaaaa aacgagatca
     7681 tacgcaatta cggttattgt tcttataatt acaaaaacca gactgatttt gatcaatctg
     7741 gtcctgaaag gattaaacaa gcgattgcca gagaagctag taaatacatt aacgattatg
     7801 atacgctgtt tatcaattct agctcgactg cgttgaaaac actggatttt cttcaatcta
     7861 accatttgac agtcattaca aacaacgtga aaatcaatta ctctccgcac aaagataatt
     7921 gtagttatat tttaactggt ggagagatgc gctttccaaa agaagcacta gtgggcgaca
     7981 tcgcattaaa tacgatttct tcagtcaatg cagacatttg tatcattggc tgtagcggag
     8041 tcgatgtagt acatggggtc acaacaaaga tattaaatga atcaacgatc aacgaaatga
     8101 tggtcaacaa gacaatcaaa tgtaagattt tagtcgctga tcatcgaaaa atcggactga
     8161 catcaaagtt caagattgct gatatttcag tctttgatta tttgatcact gataaatttt
     8221 gttctgaaaa agtattagag gagatcagaa atacggggat aaaaaccatt caagtagatt
     8281 cattttaaga accaggacgt aaatatgtaa ataggattat caaaaaaatg aataacaaat
     8341 ttatcgataa atgaaaaaca cgctacgctc aaattgataa aggaatccca agatgtatcc
     8401 atccaatcga taccatcata atctattgct tcttttataa ccgttatatg ttgcctaaat
     8461 aggaatcaaa caatatcgaa aaaaggaggt atgacaaaag tcacacctcc ttttttcgaa
     8521 taaacggtat tcaaatcaga acactgattt cacaaccact ttatttcagg tcgttttcaa
     8581 tcacctttac cgcgtaatca tttccgttga aacgcgctat tttttttgcg tccatatatc
     8641 tttctaaata atcatcttct cctaattgct tatggcaaga agcaatttca taaagcaagt
     8701 attccaatgc ataagtcgat ttatgtttct tattatactc aatacccttc tcacataatt
     8761 ggattgcttt atcataatcc tcgattttac ggtaataggt ggcgatatca taatatacaa
     8821 tgcagaccat cagattatca aaatcagtct cactcaatat tttaagtgta cgctccacat
     8881 aaactttcgc aaaatctaat tctccttttg acaagtagat cattgccacg tttgcagctg
     8941 cttgtaagtg atggatatct gtttcggtcg tttgttccaa cacttgatta aaataaaata
     9001 atgctgcatc tggttttttc gcataaagat gatcaagcag tccttgataa aataaaattt
     9061 gatttaaaag atcagaatta cttacttttt cctgatcgat cgtttgtaaa attttataag
     9121 attcttggta ttttgataca gaattcaatg attgaatctc atttattttt ttcctgattt
     9181 tgtcttcttc tgtttctact aatatatcgg agatctcgac attcagcttt ttgcaaagcg
     9241 cacttaagat attgatgcct ggcgacatat tcttgttttc gatattgctg acagttgctt
     9301 gttcacaaat gccttctgct aattgtactt gtgttaaccc ctttttcttt cggtattctt
     9361 ttagtaatgc tccatctact ttaatcaaaa caatttcctt ccctttaaaa aattatttct
     9421 cctttatatc atacacaaaa aaaagttcta aacaaccaaa aatgtttaga acagaataaa
     9481 aattttaatt ttaaaataat attcaaatta aacaactggc gtatctgctc cttgatttct
     9541 ttttgtgtta tctgaataat tatcgtttac agttataaca catagtgaaa attgtcatgg
     9601 cgagaaagtc taagaatatt tttaaacata actatttctt tcttacgtgt gtataatgac
     9661 gacagcacac ctatcaatta atataattat tttatttttt tatgttctca tgtttatttt
     9721 taatgacaca acttctcgta tttatctggc acaacatata aatcgatcaa aaaattgttg
     9781 cgtgtttttt tgaaaattgg agtttcaact tgattacaaa atttaaattt agaagttgtg
     9841 aaaacagcga gagacagttt aatattcaaa atatacatag gctactcgaa cgctgtgttt
     9901 tttagtatac tagtaagaaa cgaagggata gactcattcc aataaggagg atttcatgaa
     9961 gacaattctt tttgctcctg cagtattcaa tttagctgag acaacacgaa tgattgaggt
    10021 tgccaaagct atgaaagacc gttattactg tgtattcttt ggcttttcta aaacttttgc
    10081 tcctttgatc acagaaagtg gctttgagta tcatttacta gcgccgatcc ttacgaaaaa
    10141 acaagaagaa caaatcataa aatttgacca gttgcgtaca cttaaaaacc cttttaccaa
    10201 agaaatggtt gcctctcgta tcactagtga acagagtctg attgctaagt ttgagcctcg
    10261 actgattgtg acaggttcga atgtgacaat ttttttatcg gcccgcaata aaaagattcc
    10321 tttagtatat gttaaaccct atgctttgag tgaacctttt tttcaatcag agcatgcgct
    10381 gatgccccac gagttacgtt tcttcggccc tttaagcaat cccctttggc actggacaaa
    10441 aaagcgtata gtaaataccc gatggatccc caatgccttc aaacacgctg cacaaaaaga
    10501 aatgcttcct ttaccaaaaa caagtttaca aatgatggat gctgatctaa atctcatcac
    10561 aacgcctaaa ctatttttgg aagaagaaca gctgccggaa aattatcgaa tcgttggtcc
    10621 aatttttgct aagctcagta cttccttgcc tgaagaagtg ctaactttta tacagcgaaa
    10681 gcaacaagaa agaaaacgta ttatctattt cgcaatgggt agttcaggca atccgcgtat
    10741 gttacgcaaa attttgttct tcttacaaaa acaaccggat ctagcggtta ttgcacctat
    10801 tgactatctg cttgatgaca ttcaatctga ctcagaagat cttttaataa cagaatatct
    10861 gtctagtcat cttttgcatg aattcattga tttttctttt atccacggcg gggaagggac
    10921 cgtccaaact gcctgtgaat ccggcaaacc gtttatcggt gtggggatgc aatttgagca
    10981 aagctgtaat attgactatt gtgtaaaata cggaaacgca atcgccctca caaaaccagt
    11041 gactgaaaga aaactgcaga ttgctctgcg cgaagtttct tcacccaaga ttcgtcagca
    11101 ggcacgcacg ctgcaagccg tttttccaat aaatggtcca caacaagcaa ttcaagaaat
    11161 cgaaaccttc ctgagcaacc acccaatata gtttcaagta gaaaaagctt ttttaataga
    11221 gactcatcag taatttcgct attcgagacc cagacagtga aaatacaaaa aaagtaaata
    11281 gtggattgaa aagttagagt tacttaaatt acggtgtcta aaaaacacaa aatcatcctt
    11341 aaaataaaag atctgacgct atccaaatga gcataggtag cgtctgccat ttattcttag
    11401 tcaaattctt tgacaccttt ctctggttgg atcatctcaa cgtttcttca aaagaaagac
    11461 cataataatt aggcaaatac attttcttaa aatgtgtcat atagatctag aagcatcgct
    11521 ttgtagagat ttgtgccgct agtcccctca acaattacta aatcaaatgt aggatttacc
    11581 actttatctt tgataatcaa cctccctctt ctgttgagac aatgatctcg caatccgatg
    11641 catactccta tataaactgc cagcaatccc cacatattga gtagatcatg tcagaatgtt
    11701 ctatgtcgtc agcaacgata cactaaaagt cacgttcacc atgactgatt gctattccca
    11761 gcacaattat ttctatacac gtttcatgat ttgaataaac actcacatca tacatattac
    11821 cattcataca ccatactgca gcccctacta tatggttgta agctcccaaa tctatatttg
    11881 acttgatcac tttggtagta gatctactaa ttctaaatcc attgctgata aaatttccat
    11941 tttttcctcc ttctttctgc caaaacagtt aaaacaataa taatctttat gtaaaaaagg
    12001 gctgtgacaa aagccttgtc acagtcccat attccgaata aacggtggtc aaaagcttgc
    12061 atctgcggta ataagttcaa ccaaacgaaa aataagccaa catttcacaa aaatttaaga
    12121 agcaattttc gtaaatttct tcttatttct tgaagctaac cacttctgtt acaaccactt
    12181 ttagaacatt taaagcttcg atgtgacaaa ccatctatgc tgctcgatca taaaattgat
    12241 agcaaaaatt ccacaaagta catatgtccc ccatgaaaac aaaacattca tatgcggtac
    12301 aatgatcttt ggaagaatca cgatcaaaaa tgatgccagt gcccaaatcc atcgattgat
    12361 ttgaatatga tatgtagcta gcatattcaa tataaggtga ctagccgtta ataaaaagat
    12421 aaaaacaaaa aataaaatca gccaatacat tgtttcccac cttctaaaaa ccaaacttag
    12481 acagtctgga cttcgttttc tccacgactt tgttcatctg acagcatctt tttatcataa
    12541 gcttttacaa atggataata gataataaat gctatcaatg tgttgatcat gatcaagata
    12601 acaacacgcc agtcatttcc tgctgaaaga taaccgccga ttggagctgg taatgtccat
    12661 gttggcaaaa cagtaaatct attgaccatt tctaatttga ctgcaaaata actgataata
    12721 gtcaaaacta aaggaactaa gttgaacggg atgaacatgt aaggattcaa catcatagga
    12781 gctccaaaaa ttatgggctc attgatattg aagataccag gaataataga aaaacgacca
    12841 acctctttca agaattttga tttacagaag aatataaaca aaacagatac cacgatcgtt
    12901 gctcctgcac caccaattgt taccgtccat tgataaaact gttcaggagc gatatagggt
    12961 aattgggtgg cagctgtacc atctgccaat gcctttgcat tctcatccaa catgatcagc
    13021 cacattggac gaacaacagc ccctacaata ctcatgccat ggataccaaa tgaccacaac
    13081 aaatggatca aaaacattgg tagtaaaaca ccaagcaaat tattccctaa aatattggtt
    13141 aaaggctcga ataacgataa taaggcagcg tttacatcaa agcccgcgac gcttcgaatc
    13201 agccaagtaa ttgttaaaat gactgcacct ggaatcaatg cctcaaaact acgggcaaca
    13261 gcaggtggca cttgttctgg cattttgata gtaatatttc gatttttaaa gaaacgatat
    13321 acttccactg caaaaatcat agataagatc cccgcaaaca tcccagatgc tcccaaagaa
    13381 ctcataggta agacccagcc aagaggtgcc tcttcaggag ttaaaacgtt tacaggaact
    13441 tgtaacataa agaacgttcc taaagataat ataccacctg tcacactatc taatccatat
    13501 gatttagcta gatccgaacc cataacaaaa gttgcataaa tagccatcaa tcccatcgtc
    13561 atcctaaagg gtaaaacaat cgttgccgaa taaggggcaa taaattcatt ccatccagga
    13621 aacggtaaat tgataaagac cataaaaaat gtcccaatca aaatcaatga caatgttgaa
    13681 acaaccccat tacgaattgc taataaatga cgctgtgtac caatttttgc cattggtggg
    13741 acaagtttct cttcgaccca tttcatcagc ttttccacta aaaccactcc ttttcaataa
    13801 aatatgaacc attcattgca tgacaacgca aagaatgttc ataactaatt atataattaa
    13861 gaaattttat ttcaatatat tctcttaaat aatcaaattt atttttaaga atcctgaaaa
    13921 taagttttct aaatcatagg agcaacaaaa aaattcgata attaacaaaa atcaaaatga
    13981 ttaaatctag tgattgaaac atatcatttc aaaaaaattt tgtaaattca cccataaata
    14041 tcaccctatt taactttttt catcgtacac taaaattcaa aacaactatc tttaatcttt
    14101 acttcttggt tttgttttaa taaatttcct tcaaaaatgc ctggagaaac tacaatgatc
    14161 accgtatctt tttgtgcttg ctccaacttc ttcaaatcta taatagctaa cagtgtccct
    14221 tcttttacct cctggttact ttcaacccgt atctgaaacg gacttccttc gagttcaact
    14281 gtatctaaac ccatatggat cagtattttt ctgccagatt cactttcgat cgttatggca
    14341 tgtcgggtag gaaatatatt atcgattatt cctttaactg gcgcatggat atatccatca
    14401 tgattcgtta tagcgtatcc aactcctatc atttttgaag aaaagacctc gtcttttact
    14461 gctgttaatg gaataatttg accactagct acagctttta gaatgtttct tgttttaaag
    14521 aaatgcactt tttatcacct ctactttaat gctggccaat attttttgtt tactttgatc
    14581 atttcatcta gtattttttt tgcgactctg gcatttggta cggtttgatt caatgtaaat
    14641 gcttgtaaag ctttttgata agaaccttca aagtaagcat ctactagtaa cttctctact
    14701 gcaacttgtg cctccatcaa tcctttatga aaatcactga ttggttttct tagtgtaatt
    14761 ggctccacac cagttgcacc aacatatgcc ggtatttcaa caactgcatc tgaccgtaga
    14821 ttcggaatcg ccccttgatt aggaacgatt agcataaagc gacgacgatc atcattcaac
    14881 aaggaaatag ctatatcgac gatatattgt ccatgctccc caaaattaaa gttcaatact
    14941 tcttccacaa taccgcggcg tattttatca gccatttctt tggtattttt ctctcgtcca
    15001 tccatgacca tattagcacg tgtatactct ttgtcagtat gctcaacgac catatcagga
    15061 tataagtaat actctaagta attattcggg atattacttg gaaaattttt cgtgatgact
    15121 gacatcattt gaaaggtttt ttgccaagtt ttatctccta tattaaaatc ggcgacttgc
    15181 atttcttttg ttattagttt ttcaataatc tctggcataa tttctcgttg caattcttta
    15241 tcataaatcg atgtatacca gccaaagtgg tttaaaccat aatacgtaac gatccaattc
    15301 ttacgatcat aaccgtaatt cactgcaatc gtttcttcaa ttgaaatagt catatcacag
    15361 gcattaatca tttttacatt cggatattta cgacgaacag cttcagaaac gatcgactct
    15421 ggatttgtat aattcaaaat ccatgctttg ggggcatagt cttgtatatg atcgacaatt
    15481 tccaataaac ctttgattga gcgcatccca taagcaaatc ctccgagtcc acacgtttct
    15541 tgtcctacta atccatgttt aagtggaatc ttttcgtcct tttctcgcat ctccaatcct
    15601 ccaacacgaa tttgtgagaa aacaaaatcg catcctgtaa aagcaagctt tggatcatcc
    15661 gttgcacgaa tgcgaatatt tgaaaaacct tttcttttca gcataaattt aacaatcaag
    15721 tacatatcca tatttctttc ttcatcaata tcatataaac gtatttcaga taatggcaac
    15781 cgtttttcat tgttcaaaat ggcttgaacg attcctggtg tatacgtact cccgcctcca
    15841 gctatagtga taatctgttt tttcatcatc atcttttcct ttctattctt ctaataattt
    15901 attgaattct gccataacat aagtcacttc taagccgatg ataatttgat aatttttttc
    15961 agttggttta atgatcccgc ttatccctaa ttgcttgatt cgctgttcct cgaccatggt
    16021 gggatccact acctctaccc gtaggcgtgt attacaacta tagacatcca ggatattggc
    16081 ttttcctcca aacgcttgta gcatttttgt tgccatatat tcataatttt tacttgctaa
    16141 ccctaactct gtttcttcta aggttacttc attgccaaac tctgccttag cttcacgtcc
    16201 taatgtctga atgtttctct tattgatcaa ataataaaaa gtaacgtaat acaaggcaaa
    16261 aaagaaaatt ccgattggaa gaatcaaaat agcattggta gcgattcgaa aattgatgag
    16321 ataatcaaca atacatgctc cgaatgtaaa accaattcgt atattgaata agtaacagac
    16381 aatccctgct aaaccggcaa aaagtgcatg gatcacgtac aacataggag aaagaaacat
    16441 gaaactaaat tcaacaggct cagtgatatt tgcaataaat gaagttcctg caccgcttcc
    16501 catgattcct ttgaccatct ctttattttc tttataagct gctttataga tagctagaca
    16561 tatagctggt ataccaaaca tcattactac aaaaaaaact gataaaaaca gtccagcctg
    16621 aggatctccg ttgataaagc gtgtcatctc tcctctgaaa acttccttgc taggagatgt
    16681 atagcttcct aaatcgtaat aaatatacgt attcaacaca tggtgcagtc caaaggggat
    16741 cagcaaacga ttcaaaaaca taaatatccc cacacctaat gctcccatat caacgagcag
    16801 ttttgcaaaa ttatcaatcc caatttggat gagcggccag ataaagccca aaaaaacagc
    16861 tgcgattgtt tgtagaatca tcaccatagt caatgggaat ttttcgcccg caaaataaga
    16921 aaaaactact ggtaattttt gttctttaaa gcgattatac gtccatgccg ctactaaacc
    16981 ggaaataatt ccaccaaaaa tccccatatt cacttctggg tccataattt ctaagccttt
    17041 tttcaaggta gcaatcgcta aaaaaccagt aagtgcaggt attcctttgt ccttattttt
    17101 gacaaaaccg attgcaactc ctatagcaaa taagatatcc aagtttccaa aaacggcatt
    17161 tccagctgca ccaattactg ggatgttcag catatcgtca gctgataaac gcatgatcaa
    17221 tcccgctaat ggcatcgctg caactggaag tagcatcgct cttccaagct tctgcacatt
    17281 tgatttaaca ttcattttta ttcctcctct attaaatatc ctcatatgtt actaactcaa
    17341 tcaaaggatc atttttcact ttttgagcaa atgctgaatg aattaaaaat tcgacttggt
    17401 gggtacgagg atacacaaaa cttgaaccat ttaacaattc ctgatccaaa tacgctgcgt
    17461 gacacatgac ttcgatcgtt ttatcttctc tcaatatcat gagtaaactt gccaaatatt
    17521 cttccacact cgtattgatt tgtcgttttt tttcatcagt ttctcctacg acatcgaaac
    17581 aaggctcaaa ataatcgaca tgacgaactt catcttttcg ttcaaagttg ctccgaaccg
    17641 gcaaatcata tttttttgct aatgtaacaa ctacctcctg attttcatcc aaagtatgag
    17701 tatgatgatg actgtctaaa tgagttggta tgatccccgc atgataaatt ttttgaatct
    17761 gagcattcca ttcctgatac agttgatctt tgtcaatgtt aaatggatgc tgataataag
    17821 ataaggatct gaactctccg ctttcgataa gagtatcgac agttttgagg agtggtttgc
    17881 cacacgtcaa tgttaaatgg actcctacac ctagcctagg catttccttt cttagtttca
    17941 cagcatgctc gaaacccggc atatttgcca tcaatgtagt tgatgtcaaa attcctcgct
    18001 gataagcatc cataatccca taattcacac catggctata gccaaaatca tccgaattaa
    18061 aaatcacttt tcccatttca ttctccttct tttttctact aaaataggcg caaccaaata
    18121 atcatagtcc atttactatg tgtcatttgg ttgcgcctat agatagttac gcccttattt
    18181 taatagattc ttgctagatg aattgccaaa tagatgattt cattttcttg aatggcaagt
    18241 tgaaattgct gttcgatgat atctttaatc tttagtgctg tacaatacgc tttgctatgt
    18301 ttaaatgttt cagtaaaaaa accaatattt tctactggcg tttcttcctg ataaatcaag
    18361 cgtttaacca ggaatttgat atgaaccatt aagcgatgat aagtcagtga ttctttatca
    18421 taaacgtttg aataggattt ttctagatgg gacaaaatcg tggtcgtcat ttctactatt
    18481 tttaagctct ttaaactatt aggctctcct agctcagcat taatgatatg catagtgatg
    18541 aatcctactt catttgaccc taactcggtt tgatatcgat gattgattcg ctcgaccact
    18601 tctactgcta tatcatattc atttggataa aggaatctca tttctggcaa cataattgct
    18661 gtgacatctc tatcttctct ttttcgttga atagcaaaat aaatatgatc tgtcaatgta
    18721 atatagatat ttgaatctaa tggagaggag atcctagctg ttatcagttc aatcacttct
    18781 tccgcaaaat ccataaattc gattggaatc tgcgagacta tctcactgaa tcgtttgatc
    18841 ttttctttag aatctaatac aaataatttg tcagcatcct caacatcaaa tggcttactc
    18901 actttagcag aaaagccaat ccctttcccc atcgcaattt tttctattcc atcgtcatcg
    18961 atcaatacag cattatgatt cagctttttc atcacataca ccgttaattc acctcctcta
    19021 tatgataaaa caaaacaact tgcagactcc ttcatacata tttttgtctc caaacaattt
    19081 ttaaagacaa aaaacgacct aagaaagaac cctttcttag gtcgtgccta attgaatagt
    19141 agcaccctac ataatttaca aaaatagttt aacacataat aaaagcgtta tcaatatctt
    19201 ttttactcgt tttatgataa tacttgtatc gaattgattt ggaggtaatt acataaaaac
    19261 aaaaaaaata tagcaactct ctataagaaa gttgctatat tgataattat accggcggcc
    19321 ggggtcgaac cggcacgtcc tcaacggaca ctggattttg agtccagcgc gtctgccaat
    19381 tccgccacgc cggcaaattt aaaaataata actggggtag ctggattcga accaacgcat
    19441 gagggagtca aagtcccttg ccttaccgct tggctatacc ccaagaataa agggcgaatg
    19501 atgggaatcg aacccacgaa tgccggagcc acaatccggt gcgttaacca cttcgccaca
    19561 ttcgccatca taaaagatgt tatttaattt ctcaataaaa aactaagatg aagacatctt
    19621 agtcaatacc ggcggccggg gtcgaaccgg cacgccctca acgggcactg gattttgagt
    19681 ccagcgcgtc tgccaattcc gccacgccgg caagttgatt tattagtact aaggcggtaa
    19741 ccggatttga accggtgatg aaggttttgc agacctctgc cttaccactt ggctataccg
    19801 ccattatact attatcaatc tataaaataa agaataaatt atagaaactg gggtagctgg
    19861 attcgaacca acgcatgagg gagtcaaagt cccttgcctt accgcttggc tataccccaa
    19921 gaataaaaag ggcgaatgat gggaatcgaa cccacgaatg ccggagccac aatccggtgc
    19981 gttaaccact tcgccacatt cgccatggca ggggcagcag gaattgaacc cacactaacg
    20041 gttttggaga ccgctgttct acctttaaac tatgccccta taaaatggag gagagtggat
    20101 tcgaaccact gaaccctaag gaacggattt acagtccgtc gcgtttagcc acttcgctac
    20161 tcctccatgg tggcgcggga cagaatcgaa ctgccgacac acggagcttc aatccgttgc
    20221 tctaccaact gagctaccgc gccatatttt aaaattatta attgaataac aagaacgacg
    20281 gttccgacgg gaatcgaacc cgcgatctcc tgcgtgacag gcaggcatgt taacccctac
    20341 accacggaac cagttcatta tggaggttaa cgggatcgaa ccgctgaccc tctgcttgta
    20401 aggcagatgc tctcccagct gagctaaacc tccaacattc aattaaaatg acccgtacgg
    20461 gattcgaacc cgtgttaccg ccgtgaaagg gcggtgtctt aaccgcttga ccaacgggcc
    20521 aggtaaattt gctacggaga gtaagggatt cgaacccttg agacagtttg gcaccatcta
    20581 catgatttcc aatcatgctc cttcggcctc tcggacaact ctccagagtg aaagaagctc
    20641 aatactcttt ctcaaaatga gaactccggc agtaggactc gaacctacga catcatgatt
    20701 aacagtcatg cgctac
//
LOCUS       DAFEEZ010000048        20698 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000048
VERSION     DAFEEZ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20698
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.050"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(434..1747)
                     /locus_tag="LP245_001928"
     CDS             complement(434..1747)
                     /locus_tag="LP245_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBL1519833.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLLGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFMGFMWILNVK"
     gene            complement(1992..2216)
                     /locus_tag="LP245_001929"
     CDS             complement(1992..2216)
                     /locus_tag="LP245_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519834.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(2236..2658)
                     /locus_tag="LP245_001930"
     CDS             complement(2236..2658)
                     /locus_tag="LP245_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBL1519835.1"
                     /translation="MESVYRQERKSNRKKGQTMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGVLTFNFSDPEGNYFVIGKAESSD"
     gene            complement(2800..3510)
                     /locus_tag="LP245_001931"
     CDS             complement(2800..3510)
                     /locus_tag="LP245_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519836.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGDESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(3528..4024)
                     /locus_tag="LP245_001932"
                     /pseudo
     CDS             complement(3528..4024)
                     /locus_tag="LP245_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(4061..4513)
                     /locus_tag="LP245_001933"
     CDS             complement(4061..4513)
                     /locus_tag="LP245_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1519837.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(4648..5253)
                     /locus_tag="LP245_001934"
     CDS             complement(4648..5253)
                     /locus_tag="LP245_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL1519838.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(5703..6323)
                     /locus_tag="LP245_001935"
     CDS             complement(5703..6323)
                     /locus_tag="LP245_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBL1519839.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(6325..7194)
                     /locus_tag="LP245_001936"
     CDS             complement(6325..7194)
                     /locus_tag="LP245_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBL1519840.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANKAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(7217..7624)
                     /locus_tag="LP245_001937"
     CDS             complement(7217..7624)
                     /locus_tag="LP245_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL1519841.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDRHKLAELYEQVGLKFSELHENDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(7643..8932)
                     /locus_tag="LP245_001938"
     CDS             complement(7643..8932)
                     /locus_tag="LP245_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1519842.1"
                     /translation="MSVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     ILLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(8959..9261)
                     /locus_tag="LP245_001939"
     CDS             complement(8959..9261)
                     /locus_tag="LP245_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1519843.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(9286..11379)
                     /locus_tag="LP245_001940"
     CDS             complement(9286..11379)
                     /locus_tag="LP245_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL1519844.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLEEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(11868..12596)
                     /locus_tag="LP245_001941"
     CDS             complement(11868..12596)
                     /locus_tag="LP245_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBL1519845.1"
                     /translation="MGLCLFALPTQGFAVAGGHGGGTSSGRSSGRGSFGGRSYGGSYF
                     GSRSYGRDSYGYYGPSTGPSSYEQTGFLALAVLSVGGVSAFSIVKNKRQKKRLKSEIL
                     SRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFAEHQKVLQKNKAD
                     GVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLISGSKTQRQYFSQ
                     IWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(12742..15363)
                     /locus_tag="LP245_001942"
                     /pseudo
     CDS             complement(12742..15363)
                     /locus_tag="LP245_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298916.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
     gene            complement(15477..16808)
                     /locus_tag="LP245_001943"
     CDS             complement(15477..16808)
                     /locus_tag="LP245_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1519846.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRVMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKANFGQLNELVPFGFAGMIASFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKNAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQSGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFVGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQLIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(16774..18252)
                     /locus_tag="LP245_001944"
     CDS             complement(16774..18252)
                     /locus_tag="LP245_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1519847.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLKNPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(18557..20392)
                     /gene="tdc"
                     /locus_tag="LP245_001945"
     CDS             complement(18557..20392)
                     /gene="tdc"
                     /locus_tag="LP245_001945"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBL1519848.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEQVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     EQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIQ"
BASE COUNT         6006 a         4435 c         3469 g         6788 t
ORIGIN      
        1 atggatgttt ctattttttg cttaatcatt tattttagtc tctctcacta aaaattgtaa
       61 cgctttcaaa tagctattgc accttgttat cggtaacaga ataaaacaaa aaaacagctg
      121 aggaaattcc ctcaactgtt ttttgaaagg attgatttat tcagggaaga atgctgattt
      181 cacaacttct ttataaacgg tgttcactca gctgtccctc ggtattagct caaaaaacgg
      241 caaaatataa gaaactattt ttttcgtttt tttctctaat actcaggcca gaacactgat
      301 ttcacaacct ctttataaac ggtgttcact cagctgtccc ttggtattag ctcaaaaaaa
      361 ggcaaaatat gaggaactat tttttcgttt ttttctctaa tactcaggcc agaacactga
      421 tttcacaacc tctttatttc acattcaata tccacatgaa tcccatgaat acaaagaaca
      481 gaccatacat gatgggagat acttcttttc ctcttttagc tgctaacatg gtaattggat
      541 agaagataaa acctaatgca atcccatctg aaatactata agtcaaaggc atgccgatca
      601 agatcaagaa tgaagggatc gcaatctcta agtttcccca ttcgatttgt cgcaaagatt
      661 gtgccatcaa tactcctacc ataatcaatg ctggtgcagt tacttgtgaa gtaacaactg
      721 atagtaatgg agaaaagaac aagcctaaca agaagaaaat ccctgtagta atagctgtga
      781 tacctgaacg tcctccaacg gcgataccag ctgatgattc tacaaatgca ccaacaggag
      841 aagtacctaa taaggaaccc gcaagcatag ctgttgaatc agaagctaaa gctttcccta
      901 cacgaggcat cttgttgtct ttcatgaaac ctgcttggtt tgctaatcca actaaagttc
      961 ctgctgtatc aaagaaagtc acaagcaaga atgtcagcac tacgacccac atttgaagag
     1021 aattgatgtc ccctacatgt tttaatgcaa ctaaaaatgt tggtttcaaa cttggtgctg
     1081 cggcaacaat ttcagaaggc attggaatca aacctgtgac cagacctaaa atcgttgtag
     1141 ctgccatccc gatgaagatg ccacctggta cacgccgaac aagcaagata gcagttacga
     1201 ctaatccaaa aatcgtcaac caagtagaac caacgttgag tgatcctaat cctactaatg
     1261 tagattcatt cgaaacgatg atcccacctt cgctcagacc aaggaaagca ataaatagac
     1321 cgataccgcc agaaatcgca tatttcaaat ctgctgggat cgcatcaatg atcatttccc
     1381 gcagcttgaa gattgtgatc aaaataaaaa tcaaagaagc aacgaatacg ccggctaatg
     1441 ctgtttccca tggaatcccc attcctaaac aaacagaata agcaaaaaaa gcattgatcc
     1501 caagagcagg tgccgttcca attggataac gggctaatac ccccattaaa atacagccga
     1561 tcgcactggc taatgcagtc gcagtaaaca ctgctccttc atccattcca gaagcaccta
     1621 atacagttgg atttacaaat aagatataag ccattgagat aaatgttgta aatcctgcca
     1681 gtacctcacg ttttaccgtg gtgttcaatt tttctatttc gaagtaggaa agtatttttt
     1741 ccttcatctt ccatccccct aaatccgaac attataaata aagtccgtta aaatttcgat
     1801 ttattaataa aacaacgtgt tttatcatat actaaaacaa aacataagta aacaaaaaat
     1861 tcggatttta agcaaaatcc gaacgttcca tctgattaaa tccctttatc tcaaagttca
     1921 tgaacattca ctttggatta caagaatttc tttattgtgt taataaagtt tcttcattct
     1981 agtctcaaaa atcaatagtg tgatttgatt ttaccatttc gtttctgttc ttctttgatg
     2041 aattcttttg tatcgacagg attcagatta tttagtccgc caaaacctgt atcgaccatt
     2101 tttccccagc cttttgtctt cttttttcct gatttgagat tctttgctcg aagcttctca
     2161 ctatgttttg ctcgccgata cttcaaataa ccttctaatc ttcccattag atccactgtt
     2221 tctcctcctt tttattcaat cagacgactc agcttttcct ataacaaaat aattgccttc
     2281 agggtccgaa aaattgaaag tcaagacgcc attgttgtct gtgatttctc ctggttcttc
     2341 catgttctcg tagatagttt caaattcatc cgtaaaaaat actaaagaag gcggtggtcc
     2401 taatacctct ggtgaaaact tctgcacaaa tacttttggg aatacgccta attctaattc
     2461 ttttgagatg ctgagtacaa tactcttaaa ttcttctggc aattcgattg tttcagaaat
     2521 ttctgcacca attttttcta caaagaatcg gcaaatcatc tctacgtcat tgacataaag
     2581 catcacacgt gttttttgta tcatcgtttg acccttcttt ctatttgatt ttctttcctg
     2641 tctataaact gattccatta tatcacgaaa gcgcaaacac cttgtgtttg atactattca
     2701 agaaaaataa agcaatagtt tctaggattg ctttcctcca caaacttttt ttacaaaaaa
     2761 aaaacggcaa tgaatgccgc tcttcttatt tcgattcttt tataattctg cttctgattc
     2821 atctttggtt agtgtgtgtc taacactagt tacgccaaat gtttgatcga ttttttcctt
     2881 caacgcttcg attgcctgtg cgccacgtgc cgcttgttca gcattgatgg attcaatgac
     2941 cagcaccgct gcttgtgttt cttccgtcag catcgttctt tgggcttcac gccagttgag
     3001 acagcgacag atcgctcctt gttcatcata gtagatgatt tcttccggaa gtgccggagc
     3061 atcggaatct gcacctaaag gcaggaatga ttcgtcacct tgggcttttc ctaaatgcag
     3121 atttcctgcg atcttttcga tatcttctcc gccgcaaggt acgccaaaag acaaggaaat
     3181 actattatag atatctacaa gcggattgat tgggaaaaat tcccgttctt gatttgcacg
     3241 tttcagtaaa gcttcaatag aagaacgtgc acctttttta gtcttgaatg tggtaaatgc
     3301 ctgacgccac tgagcaatga cttcgttttg gctgaatgtt tcttctgtaa ggtaatttct
     3361 tgcttctttt gctgcctcat tcaataattg atgatacgtt tcttcacttt cttttgttac
     3421 gtggttatcg ataccattta cggataagat ttcgatggtt gcttcaggaa atacttccca
     3481 gaaattggta tccactatta cttttttcat ctgttcacac ctcttgatta gaataattgc
     3541 ttgatgaata gatagtctgt ttggggatca tctcccatat aaaaaacatg ttcgctgtat
     3601 ttgataaatc cttttttacg ataaaaagcg agcgcaacat cgttgtgttc ccaaacaccg
     3661 agccaaatgg ctgttttttg cttttctttt gctttttcaa tagctgtatc tagtaaaaat
     3721 gtaccgatac cttgatgttt aaattttttt cgtacataga ttcgctcgat ttctaaaaaa
     3781 tgatcagcca tttcctcaga ttgactcgtt cctgtattta gtttcaggta acccgcaggc
     3841 tcttgatcga tactcactag gaaaaaatct gtttctttat cttttagctc ttctgtaagt
     3901 ttttctagtg cataagcttg tgtcaagtaa tcagctaaat gctccggtaa ttatcttttc
     3961 caaatgtatc tgtaaatgtt tcgatactaa tttgttgtag taagtctaca tctgaaggcg
     4021 tcatttttcg aatttcgtat ttattcacgg cttcttcctt tcaatagatc cttttattgc
     4081 cttttttgac aaaattccaa tcttcgctaa cattcttgca tactttattt aaaagatatt
     4141 ccaattgttt tgcttcttcg tcagaaagac catttaatgc gactgcattg gagtagttgt
     4201 tttctcgaat gatgaaagga tagatttctg ctcctttttt agtcggatag agtttcttga
     4261 tttttttatt ttctttatct tccaaacgtt cgatcatccc attggattct aatttcttga
     4321 ttgctcgggc agtcgttgta cgatctactt tgatcatttc tgctagtttt tcttggatga
     4381 ttccaggatt ttcgcaaata cgtactaaat aaagatactg tcctcttgtt aaatcgactt
     4441 ctttgaattc gatattgcta atagagtcta gcgctcgggc aatcattccg atgtctcgaa
     4501 ggatttcagc catttcatcc cacctttatt ttgtttgtaa gactagttta cctctttttg
     4561 ttgcaaatgc aactattttt aataaaaaaa tcaagttctt ttttaataac tagtaaagta
     4621 tattcttttc ttcttttacg aaaaagctca atcacaatag atctggtttt tgttttctaa
     4681 aataagtaac tgtttcttcg ttgttcgctt ttctgatagc tttggcaact cttctatact
     4741 aaaaaatccc atgttggaag tttcattatt ctcaataaac ttggcctctt caccgtggat
     4801 cgcacaagca aaaacaagtt tataatactg aaaaagctgt ggaatatctt tttgtttatt
     4861 cgtatcaaaa actgctcgca actgagtagt ttctactgtt aatcctgttt cttcatagac
     4921 ttctttacgc acattttctt caggagacaa tcctatttca gcaaatccac caggaagtga
     4981 ccattctttc gtccgtttat cttcgattag taggaccttg ccatcttttt tgatataggc
     5041 acgaacatct acttttggtg ttggatgtcc ttctccaatc gttgtgagcg cttttatttc
     5101 ttcgaaagtt tcttttccta tttcactgat cagttccaat gaaatcgtcc ggatctcctc
     5161 aaaacgctct ttatcaaata catcttttcc ataatataga ccagcttgag aaagtgcgag
     5221 tagtcttttg tattgagcca acttcttgtt cattctcttc ccttcttttt tagcaaatgt
     5281 atgactatgt aatcaagtat agaagactgg tttaattacg gcaaataaat ataatgaaat
     5341 ctgcaataaa taaaagaatg ttaaaaaact cgagaacaaa agacattcga cttctctggg
     5401 gctgtgaata aatggcgttc aaaagcttgc atctgcggta ataagcccca tcaaacgaaa
     5461 aatatgacga gctattcttg tctggctgtt cttattaatt gaggcaggac agctttttca
     5521 caacctcccc actaaacggt gttctcctac caactcctcg gtcacaagtc acaatattca
     5581 tcaaacatga gaagctgttt ctttgaaatt gctccttgtg actcggagct gaacgacagg
     5641 ctcacgacct ctcggtaaac ggtgttcaaa agccaatttt tcgatattaa gccatttctt
     5701 tgttacttat tgtcattgat ttctttttct aatttatcca atagtggagt gtaatccact
     5761 tgagtatagt ctgttacatc aaattcatat agtgttccta actggaattt gtcatatttt
     5821 cggtcggcga tgatcttttt gaatgcttct ttcgtaatat gattggtccc tttcgttcga
     5881 tcttccaata cgtcaccata gtgataatga tccatgatat agctcaaatg acgatctgat
     5941 tcacgatcac gtttgtaccg acgttgccat aacacttcaa agtctgctgt taggcgaatc
     6001 gtgatcacct gatatccgta tctatctgct aattcttgga gtcgtgcttt ttgcttatca
     6061 ctaaaaggat actcggacac aatcactttc tttcctgctt ccatatacaa atcaagtgct
     6121 ttgtaataga aaggataaac tttcgtcctt tcttgttccg cccgttcttc caaattgtta
     6181 aacccgatgg attctgcata gtattccttg atttcatcga gcgtgatggc atacatatct
     6241 ggaaatcgtt cccgtagttt attcataaga tatgtttttc ctgtaccagg actaccagcc
     6301 agaagaatga aatacttttt catctcattt atttcctaag ttaattggac tttccaagtt
     6361 cataaacagt ccaatcttat gcttgacaat ttcttttact gctttatttg ctggaatcac
     6421 attatggcga agagacttgt tgatttctgt ttcactaaag gtttctttag ctactttcgt
     6481 ccagttgact aaaagctccg ttccaacatt gaatttgcgg atcccgttat tgatcaattc
     6541 aggataatct tcttctttca cacctgttcc tccatggata actaggggga catcaactac
     6601 tgcatcgatt tctttcagca agggaatgtt tacttctgtt tttgatttga attgtccatg
     6661 attcgtaccg atagcaatag ctaatgcatc cacgcctgta gcttctacaa atttcactgc
     6721 gtcttccggt cttgtatata ccttgtcatt ttcagcgaca tggattcctt cttctgtacc
     6781 gccgattgtt ccaagttctc cttctacgga aacaccgtgc gcatgggcat attctactac
     6841 tgcttttgtc ttcaagatat tttctttgaa aggtagatgg gacccgtcat acatgacaga
     6901 agtatatccg ctatcgattg cttctttgat atcatcaaag tctcgggcgt ggtctaagtg
     6961 taagactgca tcaaccattt cttcttctgc aatagctgtc attacattga ctaacacatg
     7021 catgccgata tatttagcgg tatcgacact tgtttgaata atgattggcg aacccatttc
     7081 ttttgctgcg cctagcatgg caggaagcat ttctaggtta tgcgtattaa aagctccaac
     7141 tgtaaaattc aactcttctg ctgtttttgt tacttctttc aatgttgtat acatctttta
     7201 ttgccacctt atctttttat ttgtttcctt tgatcgttac ttgttttgca atttgtcgca
     7261 tctcatccat tttgcccatg tagtaatcga tcccttgatc atcaccagca cgagcagcat
     7321 ctgcacgctt ctggttatag aggctcatca gttttttata cccatctccg atcgtctgtt
     7381 tattttccaa gctcttttct aaatattgga tggcttgatc gttctcatgc aattcagaaa
     7441 atttaagtcc aacttgttca taaagttccg ctaatttatg cctatcttgg gtagtggaaa
     7501 tctcttgttt caattgtgta atctctgatt gaatcttttc ggtcgcttct ggcgataggg
     7561 ctttttcttc ttttgccaga acttttttcg gttctttttc ttttttctta aaaaatccaa
     7621 acatcatttt ccctactttc aattaaaacg ctttcaaaac tgggcttaag atccaggcat
     7681 ataagagtgc tgcggctact gtatctacat cggttgctgt agcattgatg aatcccatcg
     7741 aattaaagat cgttactagc aaagcgggca ataatgtaat aaagaaacca tgagcaatac
     7801 cgccaatgat cgctcctcgg cgtccgccaa ctgcgttgcc aaatatccct gctgtccctc
     7861 cggcaaagaa attggttagc ataccaggta aaatcatcgc taagccgaac atgggcaaag
     7921 taaacatggc aataatcgta ccaatcgttg tcgtaatgaa acctaaaatg acggcatttg
     7981 ggctataagg aaagaaaact ggacaatcta aggcagggat cgcatcagga actaatttca
     8041 tagctatccc tcgaaatgcc ggcacgattt cacctaacag tagacgtaca ccagctagca
     8101 atatatacac acccactacg aattggatgg cttgtaaaaa ggcaaacatg atatagtttt
     8161 gatctcctga taattcagaa gcgaatggtt cgcctgcaaa taaaacagtg atgatatata
     8221 gcgggaccat cacgaccatg acagacaaat aagtatcttg cagaaattcg aaatgtgtcg
     8281 gcaacttgat atcttcgatc gactttttat tttcgccttt ctcaccaaaa agcttagcaa
     8341 caccggcttc aaataagtac ccgatcgtac aaaaatgacc taaagcaata tcatttgatc
     8401 cagtgatttt acgaatgatc ggttgcgcta ctgccggcat agcaatggcg aaacaagctc
     8461 cgataaaacc accgaccaag atcaatacga tccctcgcag accggcaaaa tagccaaaga
     8521 ctgtcgtcat cgttgccatc cataaaattg cttgaccagt taaaaaaatg tacttccatt
     8581 ttgtgaaacg agccaaaata atattgaata caaaaatggc taagaacgtc agtgcaatat
     8641 ctctacctaa acccaaatca ttcattgctt gaccattgat agattcaata gaagggatga
     8701 tcccttgcat atgaaatcct tcagtaaaga ttttcccgaa ataagttaaa cttccaacga
     8761 tgatgctcga accggcactc aacacttgaa atcctaggag tgtctttaac gtgccagaga
     8821 tgacttgtcc tgctgatttc ttctgcagta gtagacccaa catagcaatc aatgcaatgg
     8881 tgatcgatgc ctgagtcaaa atattttcga tgataaaatt gataacgctc atgtttttac
     8941 cctcttttct ttttgtattt agataactcc cttatcttgc agaactgggg tgattttttc
     9001 ttcaatttca ttttttgaaa caatattttt caaatagatc atcgccgttt taggatcaac
     9061 tgcgaacttt tcgaactgcg aacgaaaatt ttctgctgtg atgatcacat ctggtttcat
     9121 ggaaactgcg gaagaaatat cacaatggtc cagtttggct tctactccta atttgttcaa
     9181 aacatcctca gcagacatct gtgctgcaaa actacttcct aaacctgcgc cgcatacgaa
     9241 taaaatgttc aatttgttca tctttgttct cccccgtatc atttattatt tctcaactac
     9301 tgaaaaaagc agttgtttga aatcttcgat atttgtgcat tcaatcaatc gatccaactt
     9361 ctcttcgttg ttgatcaatt caattagttc tttcatgatg ttcagatggg agtaggagtc
     9421 tactgctgcc aaacaaaaaa taatctttac tggatccatt tcaggattac cgaaatcgat
     9481 tggttgctca atcgtagcta cgctgactcc taatttattg accccatctt ctggtcgggc
     9541 atgggctagt gccatgtgtt tgccaatcac gatatacggt ccgtaatcat tcactgcacg
     9601 aatcatcgct tcgacatagc gctcttcgac aatgttttct ttaaccaatg gtctagcagc
     9661 tagttcaatc gattcctccc aagtagtggc tttttctttg atcatgatat tgctgtccgt
     9721 caaaatatct tttaacatag gctggatctc ccttttgttg atttctaaat tgtttgtttc
     9781 gaataatttt tctaacttgc catagatgat tcgatctact cggccaccac tttctttcat
     9841 gacatctatt atttgagtga ataactccgt cgattcatga ctgttaggct ctaaccgctg
     9901 tagttcttca tttcttttca aaaagtcttc tataaccaag atattcgtct cagttaaaat
     9961 cggatcgaca actaaaagcg gcttatttcg ataattcaat tgaaaggtgc tgaaaaccag
    10021 attgacatcc aatttatcta ctaattcgat ttcttttgaa cttaaaactg cagtaatctc
    10081 gatctgagga aacttttctt tcagattctc tgctaacaga tttccagtag ccatcccatg
    10141 gttacagaca acgactgatt tataaacata attcaagtct cgcttgatta cactggcgat
    10201 cgtcgaaaag tggatgacaa gaaaagctat ctcgtcctcc agtatcttgc caccaattac
    10261 ttcttcgatc gtaggaacaa aatgagtgac tgcgcggtag attgggaaat aatttgttcg
    10321 gatgttttct ttcaatggat tcatgacttg gatatgattc ttgattctta caatcagtgc
    10381 agccatgtgc ttatagagat tttcgaataa ggcttcttcc tttagatgga aaggtacgtg
    10441 tgtctcgttc tctacaaatt ggatcaattg gatcgttagt aattgagctt gtacccactc
    10501 gattgaattg gagatatctc tagcattgaa cgtctcaata gtgaaacgaa gataatttct
    10561 ttctacttgc gggacattgt ccaattgaaa ttcctcgatc atgtggtcaa taaatgcaga
    10621 aaagctactg tcttttattt ctgtattttt ccaattaatg gcagagataa attcatgttt
    10681 cctgattcgc tggatccaga tcaatgtaaa aagcaggatt tgttttttat aaatatcatc
    10741 ttcttgtttc aacaacttat tggaatagat ctcctgtatt tttttgattt cctccaaagg
    10801 aaaataatgg agaaagattt tttgagccgg tgttaattgt gcatcttgat tcataaagaa
    10861 gtcggtcatt cccagattct gattgataaa atcatagatc atcgtacgga tagatcgttc
    10921 tgaaccttta taaaccagtc cttgctttcc ataactgacg atctctatcc cataactgac
    10981 cagtgttgct cgtaaccgtc tcatatcttc atctaatgta cttttagaga tttgaaattc
    11041 ttcttctttt ttgtttagat ggatcgggat tcggctgtaa gcaacggcta aaactagatc
    11101 aaaaatacgt tcgcgccgat tcaaaaagcc gtctttcaca tcttttattt cagtttctaa
    11161 tcgagcttgc ttttcctttt ccagcttcaa caaaaaacct ttgttgcgaa ttgtacggat
    11221 ctccggaagc tttttactgc tcaaccagat attcgcttca agaacttcct gacgaatcgt
    11281 ccgctgactg acattgaact cacttgctag atgttttgct tttactggat attgggctgt
    11341 catgattctg tgaagtattt caattgttct tgttttcata gaaatgatct ccttctgatt
    11401 tcaagtatat ggttccgctt acataataaa aagtagatat ttctgccact tgaagtggaa
    11461 agaaagtaag caaagcaaac aaaaaataag ccatatgctt tttcatctcc tcaacgaaaa
    11521 agacatacgc ctattattac aaaaattttg cccatctata caaaaaagag gttgtgaaaa
    11581 agctgtcctg catcaagtaa taagaacaac taaactaaaa tagtgcttcc tattttttgt
    11641 ttggttgttc ttattatcgc agatgcaagc ttttaaacac catttagtgg agaagctgtg
    11701 acagagatgt tcagccttga gcgataagaa gcgattttga aaaatcgctt cccatatttt
    11761 acaaaatcgt gccttattgc cgataggcta tctctggaac accgtttatt cagaaaaagg
    11821 agctgcgaca aggcttttgt cacaactccg ttcataaata tttcctgtca atccagcata
    11881 atcggttgaa taaaatcggc ttgccatctt ttttctttct cagaaaaatc aaaataccat
    11941 atctgagaaa aatactgtcg ttgtgtctta cttcctgaga tcaatcgccc atcttttcga
    12001 tcgactgaat aatcacagca tctgaaatca attcggatgg caaaactatt ttcgtggatc
    12061 tgtcgataat ttcctacttc ctgaatagtt atttttttag tatgatttct tacaccgtct
    12121 gctttgtttt tttgcagaac tttctgatgt tcggcaaaca gcttgtctgt ataacagctt
    12181 ctggcttttt caggagtttc ttcttcccaa gcggattgga tcttcatgaa tatcttttgg
    12241 atttccaaaa actgtgcttt cttttcttta gccgttcctg acatgcggga caatatctcc
    12301 gatttcagcc ttttcttttg tcttttattc ttgacgatag aaaaagcaga aacccctcct
    12361 actgacaaaa cagctaatgc aagaaacccc gtttgctcat aactagaagg acctgtactt
    12421 ggaccataat acccataaga atctctgccg taagaacgac tgccaaaata actgccccca
    12481 tatgaacgac cgccaaatga acctctgccc gaacttcgac cgctagatgt acctccacca
    12541 tgaccacccg cgacagcgaa tccttgggtc ggcagagcaa acaaacatag gcccactaac
    12601 aaaatgattg ctaaataatt gattttttca ttgtcttcct cgttatcttt tattacaaaa
    12661 aactattttt atcatagcct tgctaaaagg aagagtcaat aaccagatgc ataaactgtt
    12721 tttttagcaa ttttgtctta tttagtcatt gagtaacatc ggacagatgt atgtgtcggc
    12781 agtccataat tcctctatct tcagcatgaa caagcttgca gacaagagat ctgcgcttcc
    12841 tccaggagag atttggtttt cctgacaaaa gtgcaacagt gctgtaaatg gacgatttgg
    12901 taaagcactt tgactagcag catgagcaag tttttgcatt tccactaacg ttttctgatc
    12961 actgcgatgc aatacgcatg tgtcatctag cgaactcatc aaaactaaca acatatgcat
    13021 ttgtttctgt acatatgaat cattatctag ctccttagct gcttggattg caagcctgat
    13081 atgcggatac cctaatatcg cttcttcata tgcaccattt acgccatatt tttgcttcac
    13141 cctatgacca tgagtggttt ttttatgacg atattttgta tcaggaaaag cagcaagctt
    13201 gctgacatca tcaagtattt tcgataaaga aaaaggctgt tccatactga ttttttgtgc
    13261 aatgacactg atcaatagcc ccattgccca aatcgctcct ttatgggtat tgatgccatt
    13321 tgtagcaatc agcattgcct tttccgcttt tcgcccaatc tcagcaattc tttctcttaa
    13381 ctcctgatca atagcataat gccatgctat ttgagccatt tcttcaaaaa aaggagttag
    13441 cgtcttagca gacttatcca aaatgcgccg accttctttt acggcttttg cgatcgtatg
    13501 gaaattatca tctcctaaaa ccatatcagc tgcctgtttg cttacttcac tacctttgat
    13561 tcccatagcg attcctatat cggctctttt caaagcaggt gcatcattta cgccgtctcc
    13621 ggtcattccg acgatttctc catttttctg caaagctttc acgattcgca gtttgtgttc
    13681 tggtgtcgtt cgagcaaaga cgtcgacttt tggtacttgt cgaatcaact cttcttcaga
    13741 cataagatcc aaatcgatcc cttctaaaac tttagcagta tgttttaagc caatttgttc
    13801 cgcgatcgct tttgctgtat ctttgtgatc ccccgtaatc attttcactg agattcctgc
    13861 ttgttggcat tcctttacag ctttgactgc actttctttt ggcggatcaa tcaacccagc
    13921 aatccctgca aaagttaatt gggttaaaga ctcatgcgtg agttcctgtt tcgaatctac
    13981 ttttttgtaa gcaaatccta aaacacgctg accttttttc gcaaacgctg tggctgtttg
    14041 accccatgct tcttattctg aagaagaaag agttgattta gccaataata cttctggcgc
    14101 acctttgacg taaatcaccc ctcctttttc ctccgcatgc atcgttgcca tatatttgta
    14161 ttcagagctg aacggaattt ttgcttctat ttttttcaaa ggcagatcgg ctgtttcggt
    14221 gtggcgaatc agtgcaagtt ctgtcggatt gccacttaaa ttttctgttt tctgttcttc
    14281 tttcgtcttt aattcctgac aatttttcat aataaacagt acgcgagttt cttcctttgc
    14341 tgctacatcc acaactgtca tttcattttt tgtcaatgtc cctgtcttat ctgaacagat
    14401 cactgtcata gaacctaatg tttctacaga aggcagtcct ttgatgatcg ccttttcttt
    14461 tgccatttca tgtactccga cagataggat catggtcaac acagctggca atccttcggg
    14521 taccattgac accaccaaag cgatcatagc tgaaagaagg atatgccaat ccatgccata
    14581 gcggaatgtt gtaaaaacaa ctaagaacaa gatcaaacaa agaatgcctt gaaaaatttg
    14641 tttgttcaat cggttgatct tcttgatcag aggcgtcgtt tgttgttcga ccgattgcag
    14701 tgcttgattg attttaccga tttctgtcgt gtttcctgtt tctacaacga caccgactgc
    14761 agaaccagat tgtacaagcg ttcctgaaaa agccatattt ttttggtcac cgattgattc
    14821 ttctgctgcc aaaacggaat gatttttttc agatgcttct gattctcccg tcaaaatcga
    14881 ttcttctact agtagatcat gtacttcgat caaccgaaca tctgctggaa cgacgtctcc
    14941 ggcacgtaag acaatgacat ctccttttac tagttctttc gcagggattt tttcttgcat
    15001 cccgttcgat agtactatcg cttcttgtcc catcagctgc ttcaaaccat tcaacgattc
    15061 ttctgctttt ctttcttgcc aataactaac gagtccgttg acgatcacta cgaataaaat
    15121 aatacttcct tcgatgtatt cgctcgaagc aaatttcaaa aaagaggcaa tgatcaacac
    15181 gatcatcagc agatcagtaa agtgttttgc tatttttttc catcgttttg tctgctgtct
    15241 tgcttctatc tcattatatc cttgatcagt caggcgtttc tgccgttctt cttgcgacaa
    15301 gccttctgtt gatgtttgat agtttttcaa tacatcttct accgtcaatc tgtaccagtt
    15361 catcctatcc cctcctgttt aattgatact gttattatac gcagggaagt tttttcaggc
    15421 gtatcgatta tttcaggggg gtctgaaata attcgttttg cagaatgtat ctgggcctaa
    15481 ctgatatttc tattgcttat tcttttatat acaaaattta agaatacaaa ccagataacc
    15541 aataaaaaag gaataaagcg tgtcgtgctt tcgaataaca agctgaaagc aattgaagta
    15601 aaaaacacca acaaagcaag atctttatat ctttgtgtag tgttccgttt cttttcttta
    15661 attaattgaa catgtgcaca caagatcgaa gaccacacaa atagaaaaca actcgttgtc
    15721 atgcctgcca aaagctgaaa aaacaatcga ctatcagcta caaaaaaatg tagacaaaga
    15781 ccgacaaaaa ataacatccc tgtaattaaa ataccgtgta aaggtacgcc tttcttagaa
    15841 agcgcacaaa accaatgggg caaacttttc tcttttgctg tttgatataa aatcctgcta
    15901 gtactgtaga ctgcactatt tgctgaggac aaagaagcaa ccaaaatcat tagattgaca
    15961 attgctgctc cgctttggca atggatcact tgcagcatag tcactaaagg actttctttt
    16021 aaatctaaac aatgccatgg aacaacaaat aaaatcgaca aaatcgttcc tatatagaaa
    16081 aagaggatac gccaaggcag acagttgatt gcatttttca aattcttttg tgggtcactc
    16141 gtctcaccaa ctgttaatcc gatcatttca attccagcaa aactgaataa aaccatagga
    16201 aatgaagcaa tcattccagc aaagccaaac gggactaatt cattgagctg tccaaaattt
    16261 gctttgattc caatagactg ggtatgaaaa tctgagacac tcaatcctat acccaataag
    16321 ataaaaagga aaatccccaa gatcttgatg attgagaaaa aagattccaa ttcaccaaac
    16381 cacttgactg caacaaggtt gactgccatt aagatcatta gtgcgctacc tccgcttatc
    16441 aaagctggta catgtacaaa ccagaaatgg atatacaatc ctattgctgt taattccgca
    16501 agtccagctc caagccagca aagccaataa gtccaattga caaaaaatgc ccactttttg
    16561 cctaaataat agtcaacgaa atcactgata gagttaaatg tactatttgc taaaaataaa
    16621 tcacccatga cccgcatcaa accataaata gccaaaccgc atatcaaata aacgagaata
    16681 acagctggcc ctgctgatgc aattgccttt gctgaaccta aaaataatcc tgttccaatt
    16741 gcgccaccta atgcgattaa ctggatattt cgattagtta gagtccgttt cattgccggt
    16801 ttttccatca agttcacctt tttctttttc aagcagcatg gcgacttcct gttcccaaga
    16861 aggtttcttt attttttcaa tacagagtgg tactacaaac aaaatgacac tgatggctgt
    16921 gactgcaatt agattgatcc atgtcccagc tttcatcgtc agtccgacag aaaatccgat
    16981 tgccgcaaat aaaacaataa cgacagtcca aactccaaga ttgctctttt tctctttttt
    17041 tccaattcta aatggtcgat tcaactttgc atgtgtataa cgcaatctca aaactgcgat
    17101 ccccatgatg acatagacga tacagtagat aacagtagtt gaatttacga gcatcaaaaa
    17161 tgcttgattg acgccaggaa tcagcaaata aaaaagtgca aagattgaga taatgacaga
    17221 ctgagtcaaa ataacggatt tggatacgtc aaattgattc gtcttccaaa aattgaattt
    17281 tggtggatac gcaccttttc tagcactttc tgtcactgtc tttgctggtc ctgaggccca
    17341 agcagataat tggactgcta caccaatgaa gacaagtaaa ctaaacagat tcacaataag
    17401 atgtggcaaa ccaagaattt ggcaataaat cgaaatagat tgcgcgatat tattcaattc
    17461 catttgtcct tttggtacga catttgctac aactaaagca ttcaaaatat tgacgaaaaa
    17521 tataaaaatt aacgcggcaa atactccgcg aatatacgtt ttaactggat ttttcaaccg
    17581 agtgatatac acagaggaca tttcgatacc agtaaaaata aacatgatcg gcgcaaaata
    17641 aacaaatgag gatgcagtcg tagtatctgg tattaatttg tcccatgaaa aactgcctaa
    17701 tgttccggtt ggtacgatcc caactttgat ccacgcagca aaccctaata agagcatcat
    17761 cgtcaaaggc acgtacaatc ctaaccaaac accgactttt ccgccgattt ttgccatatc
    17821 aaatttcaaa ttcaaaaaag tgatgatcca ataaacgact aaaatgacaa ctaatgtaaa
    17881 tttgctgttc aaaccaagcg gcacattatc gataatatta ccaaacaacg gagcaagtgc
    17941 tgaagcgacc atcaccatcc caggaaacat ttggacccat aacagccatg agacaacgaa
    18001 cccccatttt tttcctagag cattcgatac ccaaagttct ggaccacctt tttggggaaa
    18061 cattccggca aattcaccag agatcaatga gattggaaaa gcgtacaata atactgcaac
    18121 cagcatgtaa aaaatcatcg tccagctcgt tgctgctaca tctggaatat ttcgtacact
    18181 tgctacaagg gcgcaggtca ttccgataaa ggtcatggtc gtgatttgct ttgatgaacc
    18241 agtatctttc atctttattc cttctttcaa tagcgacata tgtttttgtt ttcttttatt
    18301 tttgttcaag aacagaaatg acaaggtttc atcgattcag tacaaaaccc agtatcaccg
    18361 aaacatccat tgaacgatct tagtgaactg ggtttgatac atgaaacgaa cgatccaact
    18421 tatagaacgt tttataaaaa agaatatctt ggcgaggaat atatgaaaaa cagggggaaa
    18481 tacaattgtt ttgatgaagc aaataattgt ctgttctcca tatgtctctt gttattcttt
    18541 cacacaaaaa tcagttctat tggatgattt cgtttagttt cttttccatt gctttggcga
    18601 tttcttttgt ataaaaattg aaaattcgat catcattcaa ataaggagtc atgatagccg
    18661 cacgtagcag agtgattttc tgttcttttt tccattcttc tttcgttaga cccattcttt
    18721 caacaaaacg aatcggagaa tcaccgtaat cttcttgtgt aaatgtagta tgagaagtaa
    18781 taaaccgttc accataaaca tcgccatcca tataagaaga ccgatcgaac attttttcat
    18841 ttaattcatt gatagcgttc aaatctgtac agccttgttc tttgaatacc caattgacca
    18901 tattaaaatc aggatgattc aatggataga cttcgattgt ttttccttta acagtaaaag
    18961 tcagatgatc gagaaattct ctgaatcttt gagctgcctc gattgaagcc ccaatcaatt
    19021 gaccatatcc ggtcacattc aatggcaata cacgatgtgc tgtccagact gcggcggcgg
    19081 ttgctccagc ttttgatcct tccaaaatat aagctcctaa catatctgga gcctttactg
    19141 atttttcaaa cacatatggc gcgaaataag aaatgatatt tctcatattt ttatgtttga
    19201 ttacgattcc tccagcagca taagggacat agcccatctt atgaggatct atcgtgacag
    19261 aatccgcttc tgaaatagct ctgaaccctt catatacctc tttgtcaatc gttacgcagt
    19321 ggtggaaaac atgatgttct tcaaagaatt cagctaagga agcatacggc acaaattctc
    19381 ctgcttcgtt tagaaacagt gaacgcgcat agccgccata tgcggcatca acatgtaaat
    19441 agaaatagat cccttcatct tttaaccttt ctcttaattg gacgatttta tctacactgt
    19501 ctacttgacc ttcttctgtc gttcctacga cagcaaccac acctagaatt gggatttttt
    19561 gttcagctaa ttcacgaatt gttttttcca aagcattaat atccattcga taatcctctt
    19621 gaactgggat agcaaccatc tgatctaagc ctactccgca aatatctaac gccttcatcc
    19681 aagaatagtg ttttgtttga ggcaccagcc atttccctaa tctttggata ttttttccgc
    19741 tacgggaaga agctgctttg acctcatcca tttcttcgtc cgtaaagctt tcggtcattt
    19801 ccaaaatttc ttcaacagat aaattcaaaa gttcccactc agacattttt ttcacttgtt
    19861 caggcagcac ttccttgaca gctaaaggaa tcgatttgat gcagcgggcg taccataatc
    19921 cttcaagatt agcaatagaa ccatctgctg caatgtgtcc ccatccgtct gtcatattga
    19981 ataatgaagc aaaatcctgt cctacttctg cttccatttg cgaagttgcc atagaagatt
    20041 ccaatgcaac attatttggg ttccacagca tcgcatagtt gtaagctaat aaagcaggca
    20101 tcaatgtttc agcattcatt tgtccccagt aacggcctgc tgaatgccat gggatcgatc
    20161 ctgcgcgtaa tcgctgactg acttcatcca agacctctat catatggtcg cgggtggcta
    20221 gataatctgg agtgagctta tctccttcgc taattgcagg catatctgaa ggaatataat
    20281 tttctctcca tccaagatgt tcatctacca tcttgttcaa caacatttta taaactggtc
    20341 cattttcagc tttgtcgcct ataaagacgg ccttgatatc catatctttc atttttcttc
    20401 cctccatatt ttgttggtca atgtctcgca gatacatgtg tttatctgta acacctcttc
    20461 actatagcgc caaaaatgag aaattttttt ttataacatc aaatccacgt agatttttac
    20521 aacgcgaatt gtaaaattaa gttagaaaaa taaaaaggca tttatggtac actcaaattg
    20581 tatttccgac gaaagaaaac aaaggagtgt aaccataaat gacctacaaa catcttacca
    20641 tagacgaact gacaatgata gaatcatatt atcttcaaca taataagccg gttgaaat
//
LOCUS       DAFEEZ010000049        20596 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.051, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000049
VERSION     DAFEEZ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.051"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            2..400
                     /locus_tag="LP245_001946"
     CDS             2..400
                     /locus_tag="LP245_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBL1519849.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            384..1079
                     /locus_tag="LP245_001947"
     CDS             384..1079
                     /locus_tag="LP245_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBL1519850.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1663..2550)
                     /locus_tag="LP245_001948"
     CDS             complement(1663..2550)
                     /locus_tag="LP245_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL1519851.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2735..3574
                     /locus_tag="LP245_001949"
     CDS             2735..3574
                     /locus_tag="LP245_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL1519852.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3770..4744
                     /gene="sgrA"
                     /locus_tag="LP245_001950"
     CDS             3770..4744
                     /gene="sgrA"
                     /locus_tag="LP245_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBL1519853.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5042..5398
                     /locus_tag="LP245_001951"
     CDS             5042..5398
                     /locus_tag="LP245_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519854.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5401..6558
                     /locus_tag="LP245_001952"
     CDS             5401..6558
                     /locus_tag="LP245_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1519855.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6584..7024)
                     /locus_tag="LP245_001953"
     CDS             complement(6584..7024)
                     /locus_tag="LP245_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBL1519856.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7184..7690
                     /locus_tag="LP245_001954"
     CDS             7184..7690
                     /locus_tag="LP245_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1519857.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7858..9771
                     /locus_tag="LP245_001955"
     CDS             7858..9771
                     /locus_tag="LP245_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBL1519858.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9776..10777
                     /locus_tag="LP245_001956"
     CDS             9776..10777
                     /locus_tag="LP245_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1519859.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10979..11185)
                     /locus_tag="LP245_001957"
     CDS             complement(10979..11185)
                     /locus_tag="LP245_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBL1519860.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11831..12679)
                     /locus_tag="LP245_001958"
     CDS             complement(11831..12679)
                     /locus_tag="LP245_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1519861.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12678..13745
                     /gene="gnd"
                     /locus_tag="LP245_001959"
     CDS             12678..13745
                     /gene="gnd"
                     /locus_tag="LP245_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBL1519862.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13747..14748
                     /locus_tag="LP245_001960"
     CDS             13747..14748
                     /locus_tag="LP245_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBL1519863.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14745..15029
                     /locus_tag="LP245_001961"
     CDS             14745..15029
                     /locus_tag="LP245_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBL1519864.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15062..15859
                     /locus_tag="LP245_001962"
     CDS             15062..15859
                     /locus_tag="LP245_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL1519865.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15873..16706
                     /locus_tag="LP245_001963"
     CDS             15873..16706
                     /locus_tag="LP245_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1519866.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16724..17581
                     /locus_tag="LP245_001964"
     CDS             16724..17581
                     /locus_tag="LP245_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL1519867.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17603..18112
                     /locus_tag="LP245_001965"
     CDS             17603..18112
                     /locus_tag="LP245_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1519868.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18149..18550
                     /locus_tag="LP245_001966"
     CDS             18149..18550
                     /locus_tag="LP245_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519869.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18662..19015
                     /locus_tag="LP245_001967"
     CDS             18662..19015
                     /locus_tag="LP245_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519870.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19049..19492
                     /locus_tag="LP245_001968"
     CDS             19049..19492
                     /locus_tag="LP245_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL1519871.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19509..20594
                     /gene="uxuA"
                     /locus_tag="LP245_001969"
     CDS             19509..20594
                     /gene="uxuA"
                     /locus_tag="LP245_001969"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL1519872.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
BASE COUNT         7067 a         3173 c         4304 g         6052 t
ORIGIN      
        1 gatgacgatc tttgaaacgg ttgtaacaga tgttggtata gaagcagaag tattcaggaa
       61 agaaaaaata atgattttat ttggagatga agcaccggaa acattaacag attattgtta
      121 taagattgaa ttgaatcagg taagaaaaga aataacttgt gatatgaagc tctgttttga
      181 taaacaaatg tatgtaatca cagcagtagg agatgttgtc caaactaatt tgaatgaatt
      241 aggacatatc acgataaaat ttgatggatc tcatgagccg gaacttccag gaacaatgta
      301 tgtagaagat aaggaaatgc cgcatttaag aaaggggaca atcattaaaa tcgatcaaga
      361 ggatcagaat gggggaaagc tatatggaaa tcatgcttga tacagcaaat acaaaaagta
      421 tttattcttg tcaacagttt ttgaatttaa caggcgtaac aacaaatcct acaattctga
      481 aaaaagaagg agcgtcaaac ttcttctcgc atatgaaaga aatcaaaaaa ataatcggac
      541 agattcctat ccatattcag acaataggaa gaacggaaga agaaatgata gaggatgctc
      601 gagttatcat agaagaactg ggaaaagata cgtttatcaa ggtgccggtg aatcaagcag
      661 gccttcaagc gatcaaaaag ttgaaaaaag aaggttattt gattaccggt acagctattt
      721 acacagaatt acaagggtat ttagctatta ataatggagc agattatatt gcaccttatt
      781 ataacaggat gcaaaatcaa ggcattgatg ctatgaaagt gattgattcg ttgcggactg
      841 agatcgaacg tacgcaaaga ccaacaaaaa tattagcagc tagtttcaaa aattgtgaac
      901 aagtcactac agccattcga tctggagctc atgcgataac gttaggtaaa gagctactag
      961 atcaagtatt agagatgccc tcgattgata aagcagtgag gggcttccaa gaagattggg
     1021 tgcaaacttt ccaagcagaa acgattggtg aactaaaaaa ggtcgctgat tacttctgaa
     1081 tcaatttctc cataaaataa acgatagcct tctcgaaaac tcgaggaggc tatctgacga
     1141 ttcaatattc attaatttaa agtttgggtg actattactt atttctcatt taaacgatgt
     1201 attccctaac ctctaataca tccttgtaac tctgaagtta cgccagtttt gaataaattt
     1261 cataaaaaca aatgaaaagt gtcgcataaa aatatctttc gtgtttctct agtataacag
     1321 aataagagga acaagtccag aagggatatt tttagtcttt tttaaaataa cttttcagtc
     1381 gagtttgagt ttatgatagt tgtttttgaa gcgatacggc aagtgaaaaa atagggaagc
     1441 atgaaagaat ctacttaatg gcgcattgat tcatgtgata gaaataaaaa acttttttaa
     1501 attatatcct catgattgta acaaatccag tgatttgttt tggtacaaat aaaaaaaggc
     1561 cccgatgaag ttgtggcaaa agtggtttgc ctcaaaaata agaaggaatt tccaaaaatc
     1621 acttctcaaa ttttgccaca tccccaattg ggtcaaattt gtttatttga atatattttt
     1681 tacataagga tctttaatag ttacattgtc ttttttcatc actttacgga ttgttttatc
     1741 catgaattcc gtatcaagag tttttgcttc ggtagcaatt ttttctagct cagatttgta
     1801 tttgtcttta ttagaacctt tatcctgttt ttttaccatt tttactagat aatagctttg
     1861 ctgataagtc gttggatctg ttacaggaat gatatcagaa acttccccgt tttttagttt
     1921 aaatgctgct ttttttactt cagtaggaat ctctggattg gttgaatcaa aattcatttt
     1981 tccatcagtt tcctttaatg ttttattttt tccataagct tgaacaagct tggagaaatt
     2041 ttccccttca tttgcttctt tttttgcttt atctgcttct tctttagtcg aaaatagaat
     2101 gatctgtgta ctaacttctg gatagaattc tttccaagca gtgtctagat ctttatctgt
     2161 taattttaca ttggctttca aaccgtattg gaaagccagc atctgtttaa agagtttctt
     2221 atatgtctct tctgtttggc caactgcttt taattgttcc ttgtagtttg gaccgagttt
     2281 tttgatttgt tcattatatt cttttgttac ttcctttgaa gaaatctctt ttccgtatac
     2341 atcatcaaat gctttgaaga caatcatttt ttttaatagt gtttgattat ttgatttaac
     2401 ttttgggtta tcataaaaat cctgaactgt aagtgttcca cctttaaacg ttgcaatcgt
     2461 ttcattggac ttgctacaac ctgagaatag taaaattgca catgctgaaa ggcacataat
     2521 tagtagttgt tttttcaaaa aatttcccat cctttcctta ttaaaaacag tctaacagaa
     2581 gaattaggga gacagtcttt cattttcgta aggttgctgt agatattctt agttcgtaaa
     2641 aatctattct ctctatgatg gagaacattt acatagtttt cacgagacaa gaaagaaaag
     2701 ggttgttaaa cttaatataa aggagggatg aaagatgatc aggattattc ggttgattgg
     2761 atctgtttta atagtcttag ttggttttgt tttaggaatt cttgtcaata atgcacttgc
     2821 ggatatgttt attggaaata gtgaatggat tggagcaatt gccggtacgg tcggacattt
     2881 agctgttttt ttactagctt tatttcttgc tagtaaggtc gaaggaaaaa gaatagaaga
     2941 ttatggtgtt tctgttcgag gaaaagactg ggggtattta gcgggaggtc tcgttgttgg
     3001 aattggagtg tttctgctta ttactagtcc attatatttg acgggggcgt atcggttaga
     3061 ttcaggaaac gcaaacattg tgccgctgat aacgagtttt attttattta ttgcagtggg
     3121 ggcatcagaa gagcttttat tccgtggctt ttttcagcat cagatgctta gatttggtcc
     3181 gttaatagca atgattggat ctgctgcatt atttgctctt ttgcacggat tgaatcctaa
     3241 catgacattt ctggcagttt tcaatatctt tttagcaggt tgctttttca gcgcacttat
     3301 ctacagtaca ggaagtttat ttacggctat tggtgctcat attacttgga attggacaca
     3361 aggagctatt ttgggtatac cagtcagcgg aacgcaagaa caaggttttt tctccactct
     3421 gatccaatcg caaaatacaa taattactgg gggaaacttt ggggctgaag catctatatc
     3481 aactacatta ttcttgttag tcttgattgt tggtttgtta ctctatgcat ataaaacaaa
     3541 gcggatgaag aaatacactg ctgtttatca ataaaagatg aagaaagcaa ggctgatatc
     3601 ggtcttgctt ttttaagtct gtcattgatt aaacgaaaaa gtaaacaaat tcaagcgaat
     3661 acacgacatc ttttgttaga ttttcacaac tgactgtcgt gttctcatca ttttcatttt
     3721 atataattcc tttatcaaat agaaggtaat tatatggaga gtgatagaaa tgaagaaaac
     3781 agcgaccgta ttatttgtta ttcttgggct gagtataatt gcagcaatga ttggaatcag
     3841 tacttctgca aatgaacggg caaatgagaa tctttcattt actgtgaaaa ctgatcggat
     3901 tgtttatgac atgacacaac aagtcattac tattccagtc aaaccaaaca aaagcgtgaa
     3961 tgctagtgat gtacatgctg ttctaacata tggttgggat ggtaatggaa gttcagaaaa
     4021 agttattggg gaagtttatt taaaagacgt acaatggacc gctggtattg agtatacaat
     4081 aatgatttct gcagaactat cgattgatga gatcaagagt aaagataaag ttgatttgat
     4141 tgttttttat gatggacaga tgacgatcac ggagaatttg aaaccaagca gttggacagt
     4201 tgttggaccg ccaagcagta cggatagcac aagtagtgaa agcagtacag aaaacacgag
     4261 cggtgaaagc agtacagaga gtacgagcag tgaaagtagc acagaaaaca cgagcagcga
     4321 aagcagtacg gagagtacga gtagtgaaag tagcacagga agcacgagca gcgaaagcag
     4381 tacggagagt acgagtagtg aaagtagcac aggaagcatg agtagtgaga gtagcacagg
     4441 aagcacgagc agcgaaagca gcacaggaaa agtaaataat gaacttgatt tggtacctat
     4501 cataccaact aaggaacaaa agagaaatgc agggagcaac ctaaaaagtg tgctaaaaca
     4561 gcctgatttt gtttctcgtg gaattgatca tcaagaaaaa gcgaaagaaa cagataatag
     4621 aaaaagcgat ttaccagaaa ctggtagtag aaccttgaac aagctaatta catggatggg
     4681 tgtgttactc attttgattg taggagcaag ctattttcgt tctctcttcc atcgagtgaa
     4741 ataaagaata aaagcaacag atctaaaatt gaataaaacg atagattttt gagtgaatat
     4801 ttcattcgag agtgctgtat tgcctggcga agttgtagct ttgccagatc tatttttgtt
     4861 tactaacata tttgagaaac aggaaataac aggaacacaa atggaaaata agagcaagaa
     4921 taattgacaa tgcacactgc gcatggtagt atctctgaaa aatcagtaac gaatctattt
     4981 gtacgttatt catgtagctg tcggaataag tctaaataat agataaaaag gagtatgtac
     5041 tttgtttgaa gaatttattg atatcaatga aaggcaagta tatcaatttt tgaactattg
     5101 ttatgaaaga gacgagaaat tatatgtggt gaaggatatc gctttagatc taaactacac
     5161 cctggctaag atgaattcgg tgattcaaca agcagaatcg ttttgcgaaa ggtatccaga
     5221 atataaatta tcttttcttt cagaaaacaa gatgataaaa gtcgagtttt cttctcagtt
     5281 tttactgagt aaagtttatt ctatactttt agagggaacg attggttata ttttactgga
     5341 ttcactttac aaaggtactt atcaatcctt agaaaatctt agtcaaaaaa ttatataagt
     5401 ttgcgtacga ttcaaagaaa attaagagaa cttaatacta ttttgaaaaa ctatcattta
     5461 tcttgcagct tgaaaaaagg taatccgata gaaggagaag aataccgtat ccgatacttt
     5521 tttcacttga tgtattggca gtcattcgac gaaaatcatt ctgatatatt atcaagtata
     5581 aaaaataaac gtcaactatt agaaaaattt gcgaaacatg cgccatatac gcgtagtata
     5641 gatagaaaga aatggatcag cctactaaga atttcgttgc aacgaatgaa acaaggccac
     5701 tcgattacgt atgtcccaga agagatgaac aaatttgtgc atccattgat aacaaaagaa
     5761 gagtttacgc attacatact agagcctttt tttgaagcaa acttctggtc gatgaatcac
     5821 atcactccaa cagagcaagc ttacctttat tttatgtttg gtgtaatgaa cacctatttg
     5881 gaagaagatt tgttggatac tccagataaa gtacaagaaa gttggggctg gattgaatcg
     5941 tctattgtag aaaattttga aaaaaacttc aagatttgtt ttacaacttc agaaaaaaat
     6001 tatctatatg tcaatttggc aatgatccat ttgtattcaa gggtttttgg gacaaaaaag
     6061 aaggtggatg cttttggaaa atcagcagaa gacagagatt ttcagcatat atttccagtg
     6121 atgtatccaa tcatgcaaca gttttttagt ggggtagctc gcagaattcc agagcttaat
     6181 acttattatg aaaagaacag acggttgatt tttcaatact gtatgttagt cagggatatt
     6241 tttataaaac acgaacaacc tgtcatattc tatattcaat caaagtatgg taaaacacag
     6301 gaattatggg caaagaaaag gatattatct atgactgaac gcccaataaa atatagtgca
     6361 tccgctgatc agttacctga tattgtcatt agcgattatc ctatcgacaa aaaggcatat
     6421 gatcaaacga atacacagat attttactgg aatggacaac ctacaaaaaa tgattgggcg
     6481 cgtctgaaag ctgaaatcat aaaaatcagg aatgagaaaa atagatccat attggaaaaa
     6541 ttggatttcg ttaattaaga aaagcagatt gtttatgcca aaattaagac attgcaaaaa
     6601 gattattttc tttaaaatcg acaagatgac cagaaagcaa gagttcgttg agctcttgct
     6661 ttcttttagt tttagaaagg aacatcctga ttttatcttc gctaaatcca gtcaaaagtt
     6721 ttgcagattg gtcgtagata atcggttttt tcaataaaga aggggatgta cgaatctcaa
     6781 tatatagttc actcaaactg agttcatcta ttctgtgaac aagattttta taactaatag
     6841 aatgagtaga gagcatttcg gtcacgccgt tgtttgtcaa ttttagtaag tggataaatt
     6901 catttttggt tagtggttga cgaattaagt tctgttcgat aaacggtata tcatggacga
     6961 taagccaacg ttttgcgcgt cttgaagacg agcagccaga acctgtatac aatttaatca
     7021 tcatacattc ctccaatagc taagtattta tgaaataata acatgaagaa atagtcgaaa
     7081 agtgccattt agaggtgtaa aataagaaaa tgttgtcacg tataatggaa ctagctagat
     7141 aagaaatact attaaatcaa gaaaaaagaa agaaggcaca agtatgtcaa acacagccga
     7201 cgcaatagta gtgatcgatt tacaaaaagg ggtatgtttt gattcttcgc cgatacacga
     7261 attagaaaca gtgacagcat tagtgaataa aagaatcaaa acatacgaaa cgattgggaa
     7321 accagttatt ttcgttcaac acgaagatgc tcaattagtg ccacaaacaa aaccatggga
     7381 gctattgtcg gaattatcta ttcctgagca cagttatttt gtgagaaaaa cccatgcgaa
     7441 ttcattttat aagactaatt tgagtgtttt attaactgaa ttggactgtc attcgatcga
     7501 attatgtggg gcacaagcag agtattgtat agatacgact gtgaagtttg ctcatggatt
     7561 aggataccag cttatgatgt gtagaggagc aacgacaact tatgataatc cttttatgaa
     7621 agcaaaggaa acaatcgctt tttacgagaa aatttgggat aaacgatttc tgacattttt
     7681 ggagcaataa gttgtttctt cgtttaaaaa aagcagaatg gatactggtt tatccattct
     7741 gctttattac gtaaaatgag aaaataatcc tgttctattt ttatgggata aaccatttat
     7801 tttttgtata aaaaatgttt gcgtttacat ataattctcc tagaaacata aaaaggagtg
     7861 aatagcttga gaacaaaaca agtattaaag ggagcgttgg tcatcttatt tgctgtaagt
     7921 acaagcgtcc cgcaatggac agtatatgga gagagcattt cttccgaatc ggaatctcgg
     7981 gaggtagaaa ccacagaaac tactgatgct ggaaatgaaa cgaaatcgag tacttcacaa
     8041 acagaaacaa atactgaaac aacggttgag acatctgtta ctagcacaga tcaagaaacg
     8101 accgctacca cagataacca acaaacagaa gaagcaacag ctacaaaaat gtcaaacgac
     8161 gaatcctctt ctgctaaagt aagtgacaaa gagaatggga cagaaaatga tgatatcggt
     8221 aaaggtgaaa atttcaatgg taaagaatat ttgaattact tcggtaaaca gatgacagaa
     8281 atacttaatg gaccaacaga agacatcaag tcaaaattaa tagagttatt agtcactgag
     8341 cttgctgtta atgattatgg tgtagataaa gagattatca aacatctgat tgctacttat
     8401 ctattgtacg atatcgcttt tgcaaaaaac agtgtgttga tgtcgatgct tggaggtaca
     8461 gatgatggga caacgcctac agaaaacaca ggcttctatc caaatacaaa acaacttcat
     8521 caaactgtac taaacaaaca agatggcaaa atgatggatg tatatgcata ttatgtcgat
     8581 caaggttcag ataaaacagt catgatccat ggcggatttc gagggaattg gaataacggg
     8641 atcgttacag aagaatacaa tgatttttat aaggccgggt ataatttatt atttgttgat
     8701 tccagagcga ctggtaatag cggaggcgat tatgtgacct atggacaata tgagtcagat
     8761 gacgtccttt actggataaa tcaagaagtt cgagagcggc catctcaaaa gattttactt
     8821 tatggtggtt cgatgggagc agctacgatg atgtctgtat tagcgaaaga tattcctgtc
     8881 aatgtcaaag gaattattga aaattgcgga tttgcatcaa ttgatgaaca actacgtttt
     8941 acgtacagcc agacagtagc ccccgcacta ccggatgcca taaaaaatca gttagacatc
     9001 attggggatc aagagcatga agatttattt atgggccttt tgaaacaata ctattttgat
     9061 caggagatgc atttggatac aaaagctgct ctacctacga ttggaatgtc agattcattg
     9121 cctaaattga ttatccatgg aacagcagat gatgtagtac ctgtgtctaa cgcgcaaaaa
     9181 ttatatgagt tatcaggagg gtataaagat cttttattag tagaaggagc agggcatgga
     9241 aaggcacagg aagttgacca tgctgcctac acgaaacatg taacggactt tttgaaagta
     9301 gtgttccatg atcagataaa cgtaaagtat gtggatgaaa acaataaaag tctactcaaa
     9361 gaccaggacg aaatccagct ttacggagct tatggagaaa attatatgac agagcaaaag
     9421 acattcgaag gatacgaatt agcaaatgtt gaaggaccga ctgaagggat ttttaatgag
     9481 acgataccaa ctattatttt ctattacaaa aaaatcccag tagctccacc aaaaaagcaa
     9541 gatccgacag agaatgcaga caataaggga aagaatgaac ctcgagagga tcaatcaagt
     9601 gatgatacgc aaccgattca gatgacagtg aaagtacaaa aaaagacaga tgcaaaaaaa
     9661 agaatgttgc cgaaaactgg agaaaagaaa cattcgcttc tcatttattc aggtggattt
     9721 ttatctgtta gcacgattat cacatggatt tggcgaagaa agagagggta aatgaatgaa
     9781 atggttcaag cgaatagtga ttgcagtacc agttatcatc gtagttattt tagtcactgt
     9841 atttttgatt aatcaaatca caccaaagcc gattagcttg cttgttagaa aacaatttga
     9901 cacaagtgaa aaagaacaag tatatgcccg accagatgat ttccagcaaa aaatcgaaca
     9961 aatcgatata aaaaaagaaa tatcctatcc ttcaaagtac aaaaataata atatggatat
    10021 ctacacaccg aaagtggaaa agaaaaaatt accgattctt ttctggatgc atggaggcgc
    10081 atatgtagga ggggataaaa atgattgtcg tgattatttg gaatatctat gttcagacac
    10141 gcagcaaatc atcgtaaata tagattatga acgatcaccg gaagcaaaac atcctacacc
    10201 agttatccaa ttgaacgaag ccattcaagc agctaaaaaa gagataaaag atcaagcaga
    10261 ttggtcgaat atttcgattg gtggaaattc ggcaggtgca caaattagtg gagaatattt
    10321 gttagcactt caaaatgaag aaattaaaaa agctgatcat cttgatccga ctttggagaa
    10381 caagcagatt acgaagttta tttctttgtc tggtctgttg gatccttctg cacttactca
    10441 agtaagtgat aaaatctcta gctttcttta tgaaaaatgt ggatgggctt actttgataa
    10501 taaggacttt gaacaatcag agaaggtcaa aagtttagcc ttggtcagac atgcggatcg
    10561 ttggacgcaa aacacattct taacggatgg aaatacaaat acgtttacga aacaaatgga
    10621 agaagtaact tctgtatttg agaaagcggg ggtgaaagtc acaaaagtag attatgcgga
    10681 gaaaaatgct gttttgaacc atgaatatca gtttgatttc agcaataaac aagcgcaaga
    10741 aacatatcaa aagttagtaa tgtttttcaa ggagtaaagt cttatgatgc aaaagaggtt
    10801 gtaatctgtc acttagctcc aagtcacaag gagcaatttc aataaacaag cttttcatgg
    10861 tttatgaata ttgtaacttg tgactgagga gttagagatg gcaaggggca ccttttattc
    10921 gaaatttggg aatatcacac gattattgtc acgatctctt ttacgtaaat tttataagtc
    10981 agatttgttg ttttgatcgt ttaaaaaaag caacaaatcc gaagcctgcg gaggcaagaa
    11041 gggacaaaaa gccgagtggt aagcaaaaga atgctggttc cactaatatt ccgttgttat
    11101 tgatataagg ctgggaacaa agatgaatag caaataaaat caatgcacta gcgaaaaaaa
    11161 gcaaagaaat atggatagct ttcataagca gcacctcctt ttttataatt gtatgataaa
    11221 tagattaaga atctataaat gtgacaagtt tgttaggatg tgaataaaat gatcatctag
    11281 cgaacttgaa acaaagatgg ctaatgataa gcaattaatg attcagcaat cagataggta
    11341 caaagtttac catcatacgt ctagaccaat aatagaaaat atgggaatat aatagaaaag
    11401 atttaggata cccccaaaag aatttcccca aaaattcgat gtatcctaaa cttttttatt
    11461 ttacataaca atcatatcaa ctgtgaaata aaattacaaa tgataaccta aaatgaggcc
    11521 aaaagccagt gttatcaagg aaatacttaa ttcaccaaaa ttttttttaa ttttttagaa
    11581 aataagaaac aaaaataata aaaaaaagaa aagataaatt ttttactact gtatactaac
    11641 tttgttatcg catctaacaa gtaactcgaa taataccaat acaaccttct ccaaagatgc
    11701 gatgacatac gttctaaccc accgactatt gatgttctgt accacccttg cagaaccaaa
    11761 aaagccacta ccaaatattt ggtagtggct ttttttgttt tatggatttt tcgctttttc
    11821 tgttatggtg ctattctttg atttcagaaa tagtatgtcg aactttagcg atagaacgac
    11881 gtgattcttt ttcgttgtaa aacatcaaaa tcacatatag agagtccaaa atgcttagtt
    11941 gagaaatacg ggaagctaaa gcttcagatc ggaattctgt ttcttcagaa atagaaataa
    12001 aaacgacatc gccaagttta gcaagggaag aattagcttg gctagtaata acgattgttt
    12061 ttgctccagt ttttcttacg gtttcagcaa tatggattgt ttcttttgat tgccctgtgt
    12121 gagaaatcaa aacagcacag tctttttccg tcaataaaga agcttccatc aattgaatat
    12181 ggtaatccgt gctgtgagaa gttgcgatag gggaacgcaa aaatttatga taagcgtcag
    12241 ttgctacaat ctctgaaccg ccaacaccga aaaaatagac acgtttagat tcattgataa
    12301 tagtagccgc tttttttaga tccttttgtt gtaacaactt ttttgtgtca tttaaagttg
    12361 aaatactaga ctcgaacacc ttttgcgcca tagtgagctc agtatctgtt ttctgaatat
    12421 tttcgtggat agaaatagca gatagatcat tttcttggat caacatggcc attttaaaat
    12481 ctttaaatcc attataacca agtttttttg taaattgaaa aaaagtagag tcagcaatgc
    12541 ccagttcact tgctaaattg ctaataggac tatgacttac tttgcttgga ttttctaaaa
    12601 tataatcggc gatagcctgt tcttttgggc tgaagtcgtt gtacattgtt ttgatttgta
    12661 gtcttatgga gacgctcatg agaattcctc attttcataa taagattatc attttttccg
    12721 ttctcattaa tgttaaagat acaaggagag taggaaaaaa tcaaacaaaa aatatttttg
    12781 taaaatctat ttacaaaaaa atttttttgt ataatgaggg tataagaaat ggaggcgcta
    12841 tcatggaaat tggtgtaatt ggtttgggaa aaatgggatt gaatttagct ttaaacttaa
    12901 aagagcacca tcacaaagta caaggactcg acatttcaag tacagctgtt agtcaggcaa
    12961 gagaaaatga cattcctgct tatcaagaga tctctgaatt tctagctact tttgagcaga
    13021 aaaaaatcat ctggttaatg cttcctgctg gagagataac cgaaaacatg ttaagaaaac
    13081 tttttccaaa actcggacca ggagacatta ttattgaagg cggaaactct tattataaag
    13141 attcaatccg tcgagcagaa gagtttcaga aaaatgaaat cggttacttg gattgtggga
    13201 cttctggagg aatcgaagga gcacgacatc aagcctgctt aatgattgga ggagataaag
    13261 aaacttttct atccgtggaa caattattca aagatgtagc aattgaaaga ggatatctgt
    13321 atgctggtgc atccggaagc ggacacttct tgaaaatgat ccataatgga atcgaatatg
    13381 gaatgatgca agcaatcggt gaaggattcc aacttgtaca aaaaagtgag tatgcttttg
    13441 acttggaaca agtcgcacgt gtttggaatc atggttcggt gattcgcggc tggctgatgg
    13501 aaatcatgga agatcagtta aacgaacatc ccaatttaag taattatcgg ggaatcgttt
    13561 ctgcatcagg tgaagcaaaa tggacggttg aaacagcgct agaaatggct gttccagttc
    13621 cagtaattgc aactagtttg ttcatgagga atctttcaca ggaagaagat agtttttcag
    13681 caaaagtagt ttcagcacta agaaatgggt ttggcggaca tgaaatagtt gaaaagggtg
    13741 agtaaaatgc cagattatca tatagcaatc gttaattcca gcagtttcgg aagagtcttt
    13801 ccacaccact tggaaagatt aaagtcagtt ggagacgttc atttctttac tgttgatcaa
    13861 gagattccag gaaaagaact agcggagtta cttaaaggat tcaatatcat tattgcaagt
    13921 gttacgccat tttttcgacg agattttttt gaaaacaaag atgaactgct attgatttcc
    13981 cgacatggta ttggttacaa caatattgat ttaaaagcag caaaagaaca ccagacaatc
    14041 gtatctatca tacctgcttt agttgaacga aatgctgtag cagaaaataa tataactaat
    14101 ttgttgtcca tgcttcgacg cacgacacaa gcacaagcaa gagtcaagga cgatcgatgg
    14161 gaagatcggg cggagttcgt cggtaggacg ctgtttaaca aaacagttgg tgtgattggt
    14221 gcaggaaata ccggaagcgg agtaatcgaa attttgcgta acggttttcg ctgtgatgtt
    14281 ctagcttatg atccttacaa atcagattta tacatcgaaa gctttggtgc aaaaaaagta
    14341 gaacttcaag aattactgga acaatcagat atcatttgtt tatgtgcgaa tttgacagaa
    14401 gagaactatc acatgatttc tgataaagaa gtcgatcaga tgaaagaaaa tgtttatcta
    14461 tctaatagtg caagaggcgc tctagttgat gaagaagcga tgattaatgg tctgaaaagc
    14521 ggaaagatcg caggatatgc cacagatgtt ttagaagaag aaccgggacg tcaagatcat
    14581 ccgtatttag cgtttgaaca agtagtgatt acgccacata tatcggccta cacaagggaa
    14641 tgtttagaag caatgggtga aaaatgtgtc agagatgtcg aacagatcag tcagcacctt
    14701 cttcctgaac gttctgtcca gacaaagagc aactatataa aaggatgatg aagaaaatgg
    14761 tgaacggttt aaaagtgaaa acaggccctc aattttattt atatgaagaa ggtggtattt
    14821 caaaagtttc tgatctcttg aaatcatacg gcgcgaaaag agtactggtc acccacggaa
    14881 cggtatcatg ggaaaaggcg ctacctaaat tagtattttt gaatgacgaa acgattcaat
    14941 ttttttatca tcgttattct ggagaatgta gttatgctga agccagacga atagctacaa
    15001 tcatcaaaaa aatgaaatcg atttcgtagt tggcgttggc ggaggaaaac tgaccgatct
    15061 agtgggttat agtgccaatc ttgcaagaat cgatttcgga gtcatcccta ctttagctag
    15121 taattgtgct ccatggacac ctcttgctgt catgtataag gagaatggac aagcagaagg
    15181 gaaaacagaa cacttttaca gacaagctgc tttttttata acagatcccc aattagtgat
    15241 tgattcccct gttccatatt tcattgccgg gttagcagat acactagcaa aatggtatga
    15301 atctgagctc atcttagaac aagatttttt gcaagatgaa tcatttttga agctagcaca
    15361 agatactgcg aagatctgca aagaagagat tttgaatcat tctgctaaag caatccaaga
    15421 tatggcacaa agaaaactga catcggagtt caaacagctt tcagagatta tctttgctgt
    15481 tgctggttta gttggaggat taggagataa atacgcaaga aatgtggcag cacatgctat
    15541 gcatgacgct atcagtaaat atattccgga aagccatcgt tttctacatg gagaaaaagt
    15601 agcgtatggg attttctatc aactggcact agaaggtcgc tgggaaaaaa tagacgagtt
    15661 atatcctttg tatcgggaat tagaactgcc ggtttctcta gaacaaatgg gattatttcc
    15721 gaaagataaa cagataatag ataaaatggc tgaatttatt gattcgaaag agaaagtgca
    15781 tttgattcct atagaggtaa cacagaaatc actgatacag tcaatgatgg aactggaagg
    15841 ttatatcaga aagatctgaa ggaggaggac acatggaaac attaagtgta gtacaaagtt
    15901 tgttgattgc tttatgggta gccgcggtta tgtcccgctg gttaggtgga ggagccacgt
    15961 tgaccttacg tttttctcct ttgatgactg gattagtcgt cgggttgatc atgggggaag
    16021 ttgcacaagc gatgattgtt acagccgctt tgcaaatgat ttatatgggg gttttttctc
    16081 caggaggatc aatgccagct gaaccatcta ttgcagcagc tatcgcagta ccagtcgcat
    16141 tattagggga tctgtcgcca gaagcagcga ttgccgttgc ggtgccagtc ggattgctcg
    16201 gaagttactt gtatcagttt cgttttttca tcaatacttt tttaggtaaa tatacagaca
    16261 aagctgtaga agatttgaat acaaaagcta tggcccgatc aattattctt tatccaacgg
    16321 ttgcctcatt tttattattc gttccgcttg ttttcattgc tttatattta ggggcgccat
    16381 tgatcgctga tgtaatcaaa gctttagagg gaacagtcgt tatccacatt cttgaagtag
    16441 taggtggagg gttagcggca atcggtatcg cgacaactgt atacgttatc ggtcgaaaag
    16501 attatctggt ctttttcttc cttgcttatt ttatgagtgt tgttttgaaa tctttagata
    16561 ttacgatggt tacttatgcc atttttggga ttattatcgc tttgatcttt gtccagtcgc
    16621 aaaaagggaa acaagtacag cctgccacaa gcaataacaa ttcagcatct tttgatgacg
    16681 aagatgacta tgatgacgga ttttaattta ggaggaatgg gaaatggctg aaataatgga
    16741 taatcaaaca ggtgctcctg aagaaatcac gaaaaaagat gtaacaaaag cctatctgag
    16801 atggcatttt gcaaacgaaa ttcctcactc ttttgaacgt tacttggcgc catcactact
    16861 atacggaatg atgccaatct tgaaaaaact ttataaagat gaagactctt taaaagcagc
    16921 atataaacgg cagttactgt tcttcaacac tcaattaagc tggggtggcg gtgtgattac
    16981 tggcctaatg tcttctatgg aacagcaaag agcagaagaa gagtatgaag aaaaagagat
    17041 cttgatgcag gatgacttga tgtataacac gaaagcggga ttgatggggg cactagcagg
    17101 aatcggagat gcaatcgatt caggaaccgt ccaatatatt tttatcgcaa tcgcggtacc
    17161 ttgggcacaa cagggaagtc ctttaggcgc actttttcct tttatctgct ttgggttgta
    17221 tcaggtttta ctaggggtat ttttcgcaag acaagctttc actatgggcc gtaatgctac
    17281 aggcctaaag caaaacactg gtgttcagac agcgattgaa atgctatcag ttttagggtt
    17341 gtttatgatg ggggtgcttg cgggaaacta tgtaaaagta gaatcttcat tgaaatttgc
    17401 gatatccgga cgtgagtttg ttatccagga aattcttgat caaatcgtgc cagggatatt
    17461 acctttagct gtcgtaatgg gtgtgtactt gttctatacg aaaaaaggat tgaaagtcac
    17521 acaagcatta ttatggctga ctggaatatt aattgtgcta gcaggaatcg gtattttata
    17581 aaaagaaggg aacgtgaata agatgggtgt agtcaattta gcgcgtgtgg atgagcgttt
    17641 gatccatggg caagtaatgg taacgttatc tcaaaaaagt ggagtgaatt ccatttttgt
    17701 tgtagacgaa gttgtagcaa aagataaatt tatgagagat ctttacaaaa atgcaggaag
    17761 ccgtacagga caaaaaacaa ttgtcattac accagagaaa gctaaattct attgggatga
    17821 atatcaattt aaagaataca attgtatttt gatcgcaaaa acagtccaaa cgatttacga
    17881 cttagtaaaa cacggaatcc ccatggaaga attgaatatt ggagggattg ctcaaaaaaa
    17941 tcctgataca gatcttttag tgacgaaatc tgtttattta aataaatcag atgctgaaaa
    18001 attgaaagaa atgaatgaac aatatggcgt aaagaatatt tattttcaag ccactccatc
    18061 tgcacctaaa acaggattaa aagatgtatt gaacaagttt gatttgtcat aaacaaatgc
    18121 ttagaaaaaa gataaagagg gcgaaaaaat gaagaagaac gagctgtttc gtgattggga
    18181 atttcgttat cgctatattt accgtaagcg ccgtacaaaa aagagtaaac agcgttttct
    18241 ttcagcatta gtatcagata tttacagtat gagaacagat gtgacagtca ttgcttacga
    18301 tacgctagcc taccgatcaa aaaatattta tgttggagat atcgaaaaag cagagaaagt
    18361 tatctgtact tattacgata cacccgttca tgcattagga agttatttca tgtttgattg
    18421 gaaagaccaa aggaaaaaaa caatctactc tatattattg tccttcattt tgttgttcag
    18481 tttaggttgg tggggaatga tgatatataa caaaaatcct catcacgtat tcgatctgct
    18541 atccgtataa acaggtatca ctgtactagc atttgggagc tactttttct tattgggaaa
    18601 agcagctcgc ggatggccta gcagacaaac ttttattcga aatacttcat ccatattaac
    18661 gatgctagaa atgatccgta cgattgatga tccgagtgta gcgtatgcgt ttgttgatga
    18721 aggctgttat ggagaaaagg gcttagacag cgtgagatcg ggtatgaaaa aagaggctat
    18781 tcttttttat ctagactctg ttggggcaga tacaccgcta cagttttcgg gaaattattt
    18841 ttcaaataaa gaacagtggc tgaaacaagt tgataagttg aaagaaaaaa acgtcaatta
    18901 tatttttagt gcaagaaaaa agcaagcgca gttcttctat ttgaccaaaa cagatttacg
    18961 agggaaaaca tttaattggc aaaatgccaa tcagattatt gctctttttc gataagtaaa
    19021 aagtgcaaaa caaggagtga gaagactaat gttggaaatc atgatcgtta cacatggtaa
    19081 gttgagcgaa ggactgaaag atgcggcgga agtaattgtc gggacatcga gccatattga
    19141 aacaatgtgc ttagagtctg gggaggacat ccaaacattc ggagagaagg tcaaagaaaa
    19201 attaactatg atcaacacag cagaacccat gctagtattt gttgatctaa ttagcgcaag
    19261 tccgtacaat caagcgctct tggcagtcaa tgaactgact gaagaaaaga aagcagccac
    19321 ttatgtcata gggggcgtga atctgccaat gttgttagaa gcaatcaatc atcagatgct
    19381 tcacacaccg atagaagaag cggtggaaca aattgtcaaa caaggaaaag ataatttaac
    19441 tgtttggcat gcttcagcgg aagaaaaaaa attagatgag gacgattttt agaaggaagg
    19501 ctgaaaagat gaagtgggga tttagatggt atggtgaaaa aggggattcg atcccattaa
    19561 aatatgttcg ccaaataccg ggaataaatg ggataattgg aactttgctg actaaaatgc
    19621 ctggagatgt ttgggagatt tcagaaattg aggagttgaa agcatctgtt gagagccaag
    19681 gactggaact gcttggaatt gaaagtgtag cgatccacga tgcaatcaag gcagggacag
    19741 atgaacgaga ttactatatt gataactata tacgaacaat caaaaacttg tctcgatgtg
    19801 gggttcgatt gatttgttat agcttcaaac caatttttgg atgggcgaaa actgatttgt
    19861 ttaatgaaaa caacgatgga agctattctc ttttatacga tcagaaaatc gtcgatcaga
    19921 tggagccagg agaaatgtat caattgatac acagccagtc aaagggattc aaattgccgg
    19981 gttgggaaga agaacggttg aaaaaattcg ctcagctgga aaaactgtat gaaggaatga
    20041 ccgaagaaga attatttgaa aatctgactt attttttaga aaaagtgatt ccagtgtgcg
    20101 aaaaagcaga tgtaaaaatg gctatccatc cagatgatcc gccatgggaa ctttttggtt
    20161 ttcctagagt gacgaaaaat cttggcgact tgaagaaaat tctaaatgca gtagattctc
    20221 catataatgg actaacgctg tgcacaggat ctttaggggc aaatccggaa aacgatttag
    20281 ttgaaatcat ccatgaggta ggttcgcgca tccattttgt ccacttcaga aacgtggagt
    20341 ttttaggaga aagaaagttc aaagaaacgg cacatccctc tacagaaggc tcccttgata
    20401 tgtatcatat tatgaaagcg ttggtgcaag aagggttcga cggtcctata cgccctgatc
    20461 atggtagaac cgtgtggggt gaagtggcta tgcctggata tggcctgtat gatcgtgcaa
    20521 tgggactcac ttacatgcaa ggtctatatg aggcgataag taaggaaaaa ccactgggag
    20581 agcattatga ataaaa
//
LOCUS       DAFEEZ010000050        20360 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000050
VERSION     DAFEEZ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.052"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            291..1430
                     /locus_tag="LP245_001970"
     CDS             291..1430
                     /locus_tag="LP245_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBL1519873.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLARHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHSIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1497..2072)
                     /locus_tag="LP245_001971"
     CDS             complement(1497..2072)
                     /locus_tag="LP245_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL1519874.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQVGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2077..3051)
                     /locus_tag="LP245_001972"
     CDS             complement(2077..3051)
                     /locus_tag="LP245_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBL1519875.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPVDIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGLDGLGDTNFPMVLAKQAESL
                     HAVDFLTDYFKEKTDTSVIALGPLTNIASALKNSPSVGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFEKLKQPIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIDESICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3075..3119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3334..4302
                     /locus_tag="LP245_001973"
     CDS             3334..4302
                     /locus_tag="LP245_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1519876.1"
                     /translation="MVIFYFILILIFIGISYHFLSYFYAKKLVRAGVQRGYDWYEETG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGIPKTIKSYDGLKLAGQMFLQPTQQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLIPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPDASIILHGSSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMIMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            4415..4693
                     /locus_tag="LP245_001974"
     CDS             4415..4693
                     /locus_tag="LP245_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL1519877.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARREGKKIIPSCPYAKKEFEKKPEYHDVLRQS"
     gene            4811..5047
                     /gene="secG"
                     /locus_tag="LP245_001975"
     CDS             4811..5047
                     /gene="secG"
                     /locus_tag="LP245_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBL1519878.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAVWMILLFVLAFLSSK"
     gene            5150..5905
                     /locus_tag="LP245_001976"
     CDS             5150..5905
                     /locus_tag="LP245_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1519879.1"
                     /translation="MKRVKQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVETNVPENFEKYVRQVLKIAGKSEKEINEKAVSYRSL
                     AEHQLMDIQDQAAIAESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5908..8265
                     /gene="rnr"
                     /locus_tag="LP245_001977"
     CDS             5908..8265
                     /gene="rnr"
                     /locus_tag="LP245_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBL1519880.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILVEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSDEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDIVGRRDLRDQLIVTIDGEDA
                     KDLDDAVTVKKLENGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHEIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILEMMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8287..8751
                     /gene="smpB"
                     /locus_tag="LP245_001978"
     CDS             8287..8751
                     /gene="smpB"
                     /locus_tag="LP245_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBL1519881.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9053..9772
                     /gene="atpB"
                     /locus_tag="LP245_001979"
     CDS             9053..9772
                     /gene="atpB"
                     /locus_tag="LP245_001979"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBL1519882.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9825..10040
                     /gene="atpE"
                     /locus_tag="LP245_001980"
     CDS             9825..10040
                     /gene="atpE"
                     /locus_tag="LP245_001980"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBL1519883.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            10131..10655
                     /gene="atpF"
                     /locus_tag="LP245_001981"
     CDS             10131..10655
                     /gene="atpF"
                     /locus_tag="LP245_001981"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBL1519884.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10642..11184
                     /locus_tag="LP245_001982"
     CDS             10642..11184
                     /locus_tag="LP245_001982"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBL1519885.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            11207..12763
                     /locus_tag="LP245_001983"
     CDS             11207..12763
                     /locus_tag="LP245_001983"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBL1519886.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEETLNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12777..13679
                     /locus_tag="LP245_001984"
     CDS             12777..13679
                     /locus_tag="LP245_001984"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBL1519887.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13702..15108
                     /gene="atpD"
                     /locus_tag="LP245_001985"
     CDS             13702..15108
                     /gene="atpD"
                     /locus_tag="LP245_001985"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBL1519888.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15122..15544
                     /locus_tag="LP245_001986"
     CDS             15122..15544
                     /locus_tag="LP245_001986"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBL1519889.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            16013..16243
                     /locus_tag="LP245_001987"
     CDS             16013..16243
                     /locus_tag="LP245_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBL1519890.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            16340..17641
                     /gene="murA"
                     /locus_tag="LP245_001988"
     CDS             16340..17641
                     /gene="murA"
                     /locus_tag="LP245_001988"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBL1519891.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNCPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            17654..17830
                     /locus_tag="LP245_001989"
     CDS             17654..17830
                     /locus_tag="LP245_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBL1519892.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            17965..18261
                     /gene="yidD"
                     /locus_tag="LP245_001990"
     CDS             17965..18261
                     /gene="yidD"
                     /locus_tag="LP245_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBL1519893.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            18325..18708
                     /locus_tag="LP245_001991"
     CDS             18325..18708
                     /locus_tag="LP245_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1519894.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHH"
     gene            18877..19761
                     /locus_tag="LP245_001992"
     CDS             18877..19761
                     /locus_tag="LP245_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL1519895.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            19875..20111
                     /locus_tag="LP245_001993"
     CDS             19875..20111
                     /locus_tag="LP245_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBL1519896.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            20199..20279
                     /locus_tag="LP245_001994"
     tRNA            20199..20279
                     /locus_tag="LP245_001994"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20233..20235,aa:Tyr,seq:gta)
     gene            20286..20357
                     /locus_tag="LP245_001995"
     tRNA            20286..20357
                     /locus_tag="LP245_001995"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20318..20320,aa:Gln,seq:ttg)
BASE COUNT         6759 a         3566 c         4425 g         5610 t
ORIGIN      
        1 ttttttgcaa ctagcttctg tatatgatgt ttacaaagaa tggtacaaga aaagatcatc
       61 cttgaaaaag gaaagctaac aataactagc atcatataag agcttttaag gatagaacag
      121 tagaatagga atctatgggc aagtcctctc gtataaataa aataggaggg aagtagcagc
      181 atatttttca taaagtggct ctctttcttc atttttactt tggttgctcc tatttgaaaa
      241 ttcgagcaca ctcaaataca ataaaaagaa atggcaaggg agaggattag atgaaaaaag
      301 aagaaaaaat cgcgatttta caagagatta tccgaattaa atcagtgaat ggaaacgaag
      361 gtgaagtagc agcctatttg aataagcttt tggcaaggca tgacataaca ggagagattg
      421 tttcttacag agatggtaga gataatttga ttgctcgtta ccaaaagggc caatcaggaa
      481 aagtgttagg cctatctgga catatggatg tcgtggcggc tggtgatgaa tcgtcttgga
      541 cctatgcacc ctttgcagca gaaatccatg ggaaccgttt gtacggacgt ggtgctacag
      601 atatgaagag tggcttggca gcaatggtga ttgccatgat cgaactgaaa gagtcaggaa
      661 aaccatttaa cggaacagtc aaattattag ccactgtcgg agaagaagtg ggtgaactag
      721 gtggggaaca gctcacgaaa gcaggctatg tagatgactt agatgccttg atcatcggag
      781 agccaaccaa ttacagtttg atgtatacgc acatgggatc aatcaactat acagtcacct
      841 cgcacggaaa agaagcgcat agctctatgc cagaccaagg ttataatgca atcaatcacc
      901 taaatgaatt cattacgaaa gcaaatgctg aaatgaatca cctcgctgaa acaatcgaga
      961 atcctgtcct aggaaaaaca atccataatg ttacattgat cagtggcggg aatcaagtca
     1021 acagcatccc aagccatgcg cagctccaag ggaacattcg atcgattcca gaatacccaa
     1081 atgataaaat cattgcattg ctgcaatcaa tcgtcaatga attgaatcaa gagacagact
     1141 atcatttgga attgatgatc gattacaaca aaatacctgt caaagctgat ccagattctc
     1201 ctttgattca ttccattcag caacaattca gccagccatt acctttagtt ggagcggcag
     1261 caacaacgga tgcagccgaa tttacgaaag ctaaccattc cttcgacttt gtcgtctttg
     1321 ggcctggtgt cgttactttg cctcatcaag tagatgagta tgttgaaatc gataattatt
     1381 tggatatgat cgaaaaatat caaggaatta ttttatccta cttagcgtaa gattttttta
     1441 ataaatgaaa aaacagagcc agattagcat tattttgcta atccagctct gtttattcag
     1501 cctatttttc tttttgaata tatcaagcgt tggggcaaca tagtgatgac taatgaaaca
     1561 acgacgatag acaacaagcg atcaaggtag tctgtaccca cctgtaccaa gatcacactt
     1621 gttgtctgac ttaaacctaa cccatgtaat agctgaacga tcatactgga tcctgaggag
     1681 gtgatcccgc caaataactg aacggtaatg atcgaagaaa cgatcgttcc aggtaccgac
     1741 aaaatcaaag cgagtaataa cagtttcaag ctgtttttat ctttgccgag atatcttggc
     1801 aaaatcaatc cagcaagcaa gcctgtgaga atttggattg gcgaataata cagagaaaaa
     1861 atatctgtag tcactccact taaaataccg ctggacaatc ctgtcagcat tccaggtaca
     1921 ggcccaagca atgcaccagc aaaaatcgtt ccgatagaat cgagatagat tggcaaacga
     1981 agccataaag caatcgttcc tccaatataa ttgatcccaa tacacaaagc catcactgta
     2041 agtacgcgag ttgccatttt gtttttattc attttgttag cccatcttta acctttccaa
     2101 atctttcata atcgtttctt cttgtgcatt taaaagaacg gttaaaaact ttcggaaaaa
     2161 aagacgagta tctacttttg tcataatttt actgttagca ggtttctgcc aaaattcata
     2221 acgatcaacc aatgtttgtc cgcgacttat tccttgagtt tctacagcag tgaagctttt
     2281 aaagccttca cagatggact catcgataaa ataagcaaca gctaatggat cattgatgac
     2341 acatcctaag attctttctt gtttccagtg aaagtcaaaa taaaaacgag tgatcgcttt
     2401 tagatactct ccctcttcag gattcatttg gcagcaatat tcaaggatag tcggtgtcaa
     2461 gacgatttct cttgtcacat ctaacccaac catttctatc ggttgtttga gcttttcgaa
     2521 tacataagaa gctgcttcag gatcacacca gtaattgtat tcagcaactg gtgaacagtt
     2581 accatggctt ttgtaagttc cgcccattga gacaaaacga tccatatgtt tcccaacaga
     2641 tgggctgttt ttcaaagcag aagcgatatt ggtcaaaggc cccaaagcaa tgactgatgt
     2701 atctgttttt tctttgaaat aatcagtcag aaaatcaact gcatggagcg attctgcctg
     2761 tttggctaag accatcggga aatttgtgtc ccctaatcca tccaacccat gagtgtcttg
     2821 cgcactaatg aaaggttgct tcaaaggttt ttccattcct tgataaacag ggatatctaa
     2881 acgatcacag cgctccaaac atttcagcac attctgcgta ccgatatcta cagggacatt
     2941 cccgcaaacg acggtaatag caactacttc gatatcaggg gatttgacag ctagtgataa
     3001 agctaaagtg tcgtcgatcc ctggatcgca atcaataatt actttacgca ttatttccaa
     3061 tctcctttct ttagagatac ttagtttttt attctgggaa gtttccgaac cagtccaaga
     3121 cgagtgtctt gtttataatg cacgaaatta gtatactggc ttttattgtg aatgtaaatg
     3181 ctctcttaca agtaaatcta ttgagaagaa ctttaagtaa atgatacaat gaaaaagaaa
     3241 tggaatttac gtgtgccgaa gaaaaagaat cctattgatc ggtatattgt ataataaata
     3301 gattatagtt tggcagaaag cggcgggtgt acgatggtta ttttttattt cattcttatt
     3361 ctgatattta taggaatcag ttaccatttt ctttcttatt tttatgcaaa gaaattagta
     3421 agagcggggg tacagagagg ctatgactgg tatgaagaaa ctgggcaccg cttgatggat
     3481 cctgctgcag tcacgtcagt agaaaaaaag cgacaaaaat tagaagaaga gtgtgaaagc
     3541 ttctgggaac aaggaatacc gaaaacgatc aaaagttatg acgggttgaa actagctgga
     3601 cagatgttcc tccaaccaac tcagcagaat aaatgggtca tttgtgtaca tgattatcga
     3661 agtacaggga aaagagatat gtctcatata ggtaaaagat atgcagagaa aggattcaac
     3721 gttcttatac ccgatttacg tgcgcatgga gaaagtgaag gagaaatcat cggaatggga
     3781 tggctagacc ggctagattt aattgcatgg atccaactca tcttagatga acaaccagat
     3841 gcatccatta ttttgcacgg cagttcgatg ggcgcttcta ctattatgat ggcaagtggt
     3901 gaaaagcttc catctgcagt caaaggattt atcttagaca gcggatatgt ttctgtttat
     3961 gcggaatttc ggtatatgtt aagtaaaatc acggtctttc ctaaaaaaat gatcatgaga
     4021 tatgcgaatc actatgctca gaaatacgca ggttattctt taaagcaagc atcagctaca
     4081 agacagcttg gtagtaacca tttgcctttg ttagtcatcc atggtgaaag agatcatttt
     4141 gttcctacag aagcagcata cacgattcaa aacgctacgg caggggataa agcattactg
     4201 cttgttccag aagcagaaca tttggaagca tcgatgaaag atccgaaaac ctattggaca
     4261 gtgatttttt catttattga acaaagaata acgatggatt gattttctct tcctttttgt
     4321 aagcaacacg aggataaata attgtttata gaccatgaga ctgttaaaat aaggtaggaa
     4381 taaaaaaata tcagttattt gaggagtgcg gcatatggaa atcaaagagg aaaaaaatcg
     4441 tcttgcttta ttcaatgatg agcaacaaga aatcggagaa atgacatggt cggatgcggg
     4501 gccagacatc atgatcattg accatacatt tgtcgatcca gcatatcgtg gtcaaaaatt
     4561 agctgaaaag ctagtgtata ctggagtaga actagcaaga cgagagggga aaaagattat
     4621 cccttcatgc ccttacgcaa aaaaagagtt tgagaagaaa ccagagtatc atgacgtctt
     4681 acgccaatca taataataac agctgaaaga tttgcacttt cagctgtttt tccatttata
     4741 tagagttgtc acggagtttt atctatgata aagttaaaga gacgatatct tttgggaagg
     4801 aggctgctat atgtataatt taattttggg aatcgtgatc gttttatcga ttgttatggt
     4861 cattgcgatt atgatgcagc caagcaagca aaatagtgca gcgagtgcat ttaccggcgg
     4921 tgcggatcaa ctattcggca aacaaaaagc tcgcggcttt gaagctgtca tgcagcgatc
     4981 aactgcagtc atgggagctg tctggatgat cttattattt gtcctagcat ttttatcttc
     5041 gaagtagtcg aataagcctc tcgcacaacg gcgggcggct ttttttattg caaagagaac
     5101 gcttaagaag aagttatgaa agaaactatg gtaaaatgag gcgaaagagg tgaaacgagt
     5161 gaaacaatta ccaaaacccc tttatgcaaa acatggaaaa cgagcagttt tgctgcttca
     5221 tgcgtactca ggaagtccaa atgatgtccg gatgctcgca cggtttttag aaaaagcaga
     5281 ttatacagtc tatgcgccgc tatttaaagg acatggaacg atggagccat atgatatctt
     5341 gcaagaaaaa gcagaaagct ggtgggcaga tactaaaaaa gctatccatt ttttacagtc
     5401 tgaacagttt tctgatattg ccgtattggg attatcgatg ggtggcatct ttgctgtacg
     5461 ggcactagaa gaagaatcag taattggcgg cggttttttc tgttcgcccc tgtctcctgt
     5521 agaaacaaac gtgcctgaaa attttgaaaa atatgtacgt caagtgctga agatagcagg
     5581 caaatcagaa aaagaaatca atgaaaaagc tgtgtcttac cgctcgttag ctgaacatca
     5641 attaatggat atacaagacc aagcagcaat cgcagaaagt agactatcag atatccaaca
     5701 gccaatattt ttagctcaag ctgggaaaga tgaaatgatc gacccaaatg gtgtatttga
     5761 aacggcacgc aaattgagcc gccaacgagt gacacttcaa tggtatcctg aaagcggtca
     5821 tgtgattaca gttggcacag caagacgcga attagaaaaa gacgtgttgg aatttttaga
     5881 aaaattacct tggaatgagg aataaatatg acaaaagaaa caataaaaga gaaaattctc
     5941 tttttcatgg aaagcagtcg caaacgtagt ttttctatgg aagaaatcgc tgaaggtcta
     6001 ggctttcaaa aaagcgatga ttttaaatta ctagtacaaa cgattgctca aatggaaaga
     6061 gaacagagta tcgttttcaa taaaaaagga aaagtcaaac ttcctttaaa accgatcttg
     6121 gtcgaaggga catttcgggc aaatgaacga ggatttggat ttgtaacgat tgatcccgaa
     6181 gaagatgata tctatatccc gaaagaagcg actggctttg caatggatgg ggataccgta
     6241 gcaattgata tcatgaagcg agcaaataca gatatggatc gcggagcaga gggaaaagta
     6301 gtggagattc gagaccgagc gactactcag ttagccggag aatttgttgc ttattcagac
     6361 gaagagatac aggaaacgga tctttatggt gtggtcatcc cgaaagatag aaagcttaac
     6421 caattcaaag tgtatgcagc ggcagaggga gttcgtccag ttgacggaag tattgtattg
     6481 atcgaactga cccattaccc tgaaaaaggg tatgcaacta gtttagaagg gataatcaag
     6541 caagtgattg gtcataagaa tgaccctggc atggatatcc tctcgattgt cgtggctaac
     6601 ggtattccta caaaatttcc tgatgatgtg ttatctgagg cagatgaagt tccagaccag
     6661 atcagcgaaa aggatattgt tggacgcaga gatttaagag atcagctcat cgttacgatt
     6721 gatggagaag atgcaaaaga tctagatgat gcagtgacgg tcaaaaaatt agaaaatggt
     6781 aattattttc ttggagtaca cattgcagat gtatcttact atgtgacgca aggcagtcaa
     6841 ctggacagag aagcatacga aagaggaaca agtgtctatt tgaccgatcg agtgattccg
     6901 atgatcccac aacgtttatc caatggtatc tgttcattga atccccatgt tccacgactc
     6961 accatgagtt gtgaaatgga gatcgatcca aatggacaag ttgtctctca tgagattttt
     7021 ccaagtgtga tccaaacaac agaacggatg acctacacag ctgtcaatca aatcttagaa
     7081 gatcaagatg aagaaacgat gcaacgttat gctcagctcg tgcctatgtt ccaagaaatg
     7141 ggtgaattgc atcgaatcct tgaaatgatg cgaatcaaac gtggagcgat ttcttttgag
     7201 gatcgtgaag cgaagatcct tgttgatgct gaaggacacc caaatgatat ccagctaaga
     7261 agcagaggga taggtgaacg cttgatcgaa tcctttatgc ttgctgccaa cgaaacggta
     7321 gctgaacatt ataataaatt aaatcttccg tttatttatc gaatccatga acagccaaaa
     7381 gaagaaaaaa tgcagcgctt ctttgatttt gcttcagctt tgggcattct ggtccgagga
     7441 acgaaaggaa cgatcacacc aaaagattta cagcatgtga tcgaaggagt agaagacaaa
     7501 ccagaagctg cagttatcaa tactatgttg ctaagaagca tgcaacaagc acgctattca
     7561 gaagacaatt ttgggcatta tggcttagcg gcagattact acacacactt tacatctcct
     7621 attcgacgct atcccgatct aatcgtccat cgtctgatcc gttcttacag tgaagataaa
     7681 agtgaaagca atcaaagttc gtgggctgcg gaacttcctg aaattgcaga tcatagttct
     7741 aagatggaac gtcgtgcagt agaaacagaa cgtgaagtag attccatgaa gaaagcagaa
     7801 ttcatgatgg acaaagtggg agaagaattc gatgggatca tcagctctgt tgtgaaattc
     7861 ggcctgttta tcgaactgcc gaatacagta gaaggattga tccatatcaa tgaattgaaa
     7921 caggactact tccattttgt tgaaaatcat ttagctcttg taggtgaaag aactggtctg
     7981 acttttaaaa tcggacaaaa agtgcgcgta aaagtagtca aagctgatcc agatgaacga
     8041 gcagtggatt ttgaactcgt ttccgcagaa gaggtcactg cgttggaacg tccaaaagca
     8101 cgcaatggaa aatctggaaa acgagaagga aaacaagcag gcaaacgctc agaaaaaaat
     8161 ggcaagaaga acaaacgata tagtgatagt aagcaaacgt tcggtaagaa aaaagggaaa
     8221 aagccatttt acaaaggtgt caaaaagaag aaaaagaaaa aataaaatga gttggaggaa
     8281 acagctatgc caaaaggcga gggaaaacta attgcacaaa acaagaaagc tcgccatgat
     8341 tattcgatca tcgacacgat ggaagcaggg atggtcttgc aaggaacgga gatcaagtcg
     8401 atacgaaaca gccggatcaa tctgaaagat ggatttattc gcgtccgcaa cggggaagct
     8461 ttcttgcata atgttcatat cagtccttat gaacaaggaa atatttttaa tcatgatccg
     8521 ttgcgcacga gaaagttatt attacacaag aaacaaatcg ttcgtcttga aaacgaattg
     8581 aaaaacactg gaatcactgt tgttccttta aaagtctata ttcgtaacgg ctatgccaag
     8641 gtattgattg gtctggcaaa agggaaaaaa tcgtatgata aacgggaaga tttgaaacga
     8701 aaagatatcg atcgacaaat tgatcgaaca ttaaaaaatt tctctagata atttcattat
     8761 cctttttcgc atattcggtg cttttgcttt tacttaatga taaaatttgt tagcatttaa
     8821 tctgataaaa catgattatc acaggttttt tcttagatca ggagcaccgt gcatggggaa
     8881 aaattcgctt cgtttttgac tgaaataaaa aagtgtctaa ttttcatgaa aatgttttga
     8941 attttctgtt tcatggtggt atgataccgt gtggttagaa accgattgga aaaaaccaga
     9001 tacgcacatg aattgatttt atgtgaattt cggggaaaag aggtgaaatg gattggatga
     9061 acgctcgcta acgtttcaca ttggaccaat ttggtttgat ggtacagttt gtataatggt
     9121 gttactgacc tgtttgattg ttttcttctt agcttacttt tttacaagaa atcttaagtt
     9181 gaaaccaaca ggcaaacaaa atgcgataga atgggtcatt gattttagtc gaggaatcgt
     9241 aacagataat ctgcctagaa aagaattgag caatttccat ttgttggcat ttacattgtt
     9301 tttatttgtt tttgttgcaa acaacatagg tttagtaaca aaaatcgtct tacctaacga
     9361 aacaacactt tggaaaagcc cgacagcaga cccgtttgtt actttaactt tggcatttat
     9421 aatgatctta cttactcact tattcggggt gaaaaagtta ggcttcaaag gatatttcgt
     9481 aaattcgttc ttgaaaccct atagttttat gtttccgatg aaactgattg aagaatttac
     9541 aaacttatta acacttgctt tacgtcttta tgggaatatt tatgcggggg aagttttgct
     9601 aaccttgatt gcaaaaatga tgacaagctt aggctggttc tcattaccat tagcaattcc
     9661 attagagatg gtctggatcg cgttctcctt gtttattggg agcatccaag catttgtctt
     9721 tgtcactttg tcaatggttt atatgagcca taagattgaa gtagaagaat aatactcggt
     9781 taaaaaacaa actactattt atctatttta ggaggaaaac aattatgaat tatatcgcag
     9841 cagcaatcgc aatcatggga gcagcaatcg gagccggtta tggtaacggt caagttatct
     9901 ctaaaacaat cgaatcaatg gctcgccaac ctgaaatgtc tggtcaattc cgtacaacaa
     9961 tgtttatcgg ggtagctcta gttgaagctg ttcctatctt aggggtagtt atcgccttga
    10021 ttctagtttt tgccgtttaa ttgaatcagt attaaggcag aaacaacatc gtttgttact
    10081 gcttttttac atggaaacta gaaatactcc aaagaaagga aggctcgcct atgctgaatc
    10141 aattggcaat tgcagaagtt ggcaatgcga tgttaggtaa tatcatcgtt gtcagcggct
    10201 catttttgat actactggct ctcttgaagc actttgcttg gggaccaatc agcgatattt
    10261 tgaaaaaacg tgaagacaag atcgccaatg atttagattc tgcagaacaa tctcgcatca
    10321 actcagcgaa aatggaacaa gaacgcgaac aacaattgtt agcctctcgt tctgatgcag
    10381 ctgatatcat caaaaatgcg aaagaaagtg gagaattaag ccgccaaaat attttgaagg
    10441 atgctcaaga agaagcagct cgtctaaaaa gcaaagccca agctgatatc actgtagaac
    10501 gtgattcagc gctgaactct gtaaaagacg acgttgcaga actctctctt caaatcgcgg
    10561 aaaaaatctt gaacaaagaa ttatctccag aaatgcatga atcattaatc aatcaataca
    10621 ttgaaggtct aggttcttca aatgaaacta gataaatata cagtaggaag acgttacggg
    10681 aaagctttat ttgaactggc gatcgattca aatcaagcag aagaaatcta tcaagatctc
    10741 gtaagtttac gtcaaatcta tgaacaagta cctggattag ggaatatgtt aagtgatgtt
    10801 cgtctagaac ctcatgaaaa acgagaaatc atggacaagc ttgtcagcgg ttatgatgga
    10861 atcgttaaaa actttttaga agttgtttat gagtataacc gaatggatga ccttttgttc
    10921 atgattgaag aatatgaacg tcgatatgat gaacatcaag ggttactatt gggaagtgtc
    10981 acaacagcag tcccactttc agacgaacaa cgaatacaat tagaaaagaa tgttgcaaaa
    11041 acaatggact atcaatcagt tgaattaaaa caaatcgttg attcttctat tattggtggc
    11101 gcgattgttg aagccaacca tcgagtaatc gacggaagca ttcgcacgca attagaaaaa
    11161 atgcgtaatc aattaaacag atagtacaaa gaggtaggtg aatcgaatgg ccatcaaagc
    11221 agaagaaatt agtgccttga ttaaagaaca aattgaaaat tatcaaaacg tgctttcagt
    11281 cgaagaaatc ggtaccgtaa cttatgtagg tgacgggatc gctcgtgcac atggtttaga
    11341 aaacgcgatg agtggtgagt tgcttgaatt ttcaaacggc tcatacggaa tggcgcaaaa
    11401 cttagagtca aatgatgtag gtatcattat ccttggcgat ttcgagtcca ttcgtgaagg
    11461 agataaagta aaacgaacag gtaagatcat ggaagttcca gttggagagg ccttgatcgg
    11521 tcgggtagtc aatccgctag gtcaaccaat cgacggacta ggtgaaatcg ttactgacaa
    11581 agctcgtcca gtagaagcga tggcaccagg tgttatgcaa cgtaaatctg ttaacgaacc
    11641 aatgcaaaca gggctaaaag cgatcgacgc ccttgtgcca atcggacgcg gacaacgtga
    11701 attagtcatc ggtgaccgta aaacagggaa aacttctatt gcgattgata cgatcatcaa
    11761 ccaaaaaggt caagatatga tctgtatcta tgtagcaatc ggacaaaaag attctacagt
    11821 tcgtacacaa gttgaaacat tgaaaaaata tggcgcaatg gattacacaa tcgttgtgaa
    11881 tgccggtgcg tctcaaccag caccattact ttatatcgca ccatatgctg gtactgcaat
    11941 gggtgaagaa ttcatgtaca acggtaaaca tgtattgatc atttttgatg atctttcaaa
    12001 acaagctgtt gcttatcgtg aactttcctt gctacttcgc cgtccaccag gtcgtgaagc
    12061 ttatcctggg gatgttttct acttgcactc acgtttatta gaacgtgcag caaaattaag
    12121 tgatgatcta ggcggcggtt caatgactgc tttgccattt gttgaaacac aagctggaga
    12181 tatctctgct tatatcccaa caaacgttat ctcaatcact gacggacaaa tcttcttaga
    12241 aagcgacttg ttctacgcgg gtactcgtcc agcggttgat gccggactat ctgtctctcg
    12301 tgtagggggt tctgcgcaaa tcaaagcaat gaaaaaagtt gctgggactt tacgtctaga
    12361 cttagcaagt tatcgtgaat tagaagcatt tacacaattc ggttctgatt tggatgcggc
    12421 aacacaagca aaactaaatc gtggacgccg tacagtagaa atcttgaaac aaaaactgca
    12481 tgcaccgcta gctgttgaga aacaagtagt gattttgtat gccttgacac atggattctt
    12541 ggacagtatc cctgtagaca gtattttaga cttcgaacat gaattattcg aatatctgga
    12601 taccaatcat tcagatattt ttgaaacaat ccgtacaaca aaagatcttc cagaagaaga
    12661 aacgttgaac agtgcgattc aggaatataa agacatgttc ttagctacaa aaggaaataa
    12721 ttcctctaca gaagataaat tgaaatccat tcaaaatgca tagtgaggtg agatgaatgg
    12781 gtgcttcatt aaatgaaatc aagacacgta tcgcttcaac gaaaaaaacg agccaaatca
    12841 cgcgggcaat gcagatggtg tctgcttcta agttgacaaa atctgaagct tcttcacaga
    12901 agtttcaggt ttatgcaaca aaagtaagag aaatcgttac gcatttgact gctactcagt
    12961 taaatgatat tgcctcagaa aatcctagag gggatatcaa ttacaacagc atgctgctca
    13021 gccgtcctgt gaagaaaacc ggttatatcg tcatcactgc agatggcggt ctggtcggtg
    13081 gatataacag ttcgatattg aaacaaacga tgtctatttt agaagaagac caccaatcac
    13141 ccgatgatta cgtgatgatc gcaattggcg gaactggtgc agacttcttt aaagcacgcg
    13201 gtatcaacct agcatatgag ctgcgcaatt tatctgatca gccaagcttt gatgaagtcc
    13261 gcaaaatcgt aaatatggca acaactatgt accaaaacga agtattcgat gaattatacg
    13321 tatgttataa ccatcatatc aattcgctaa ctagtcagtt tcgtgtagaa aaaatgctgc
    13381 caatctcaga cttagatcca gaagaagcaa cgactttcga acaagaatat atttttgaac
    13441 cttcaaaaga agaaatcttg tctcagttat tgcctcagta tgctgaaagt ttgatctacg
    13501 gtgcgatcgt tgacgccaaa acagcagaac atgctgctgg tatgacagca atgaaaacag
    13561 caactgataa tgctgctaat atcattgatg agctgacggt ttcttataac cgtgcaagac
    13621 aaggggctat tacccaagaa attaccgaaa ttgttgccgg agcttcggca ctagaatagt
    13681 attgagattg gaggaaaaaa gatgagttca ggcaagattg ttcaagtaat cggtcccgtt
    13741 gtcgacgtgg aattttcttt agaccaatcc ttaccagata tcaacaacgc attagttgtt
    13801 tataaaaatg acgaaaataa atcaaaagtt gttcttgaag cagcgttaga attaggggac
    13861 ggagtgatcc ggaccattgc gatggaatca acagatggtt tacaaagagg aatggaagtc
    13921 attgatacag gcaaagcaat ctctgttcct gtaggtaaag aaacattagg tcgcgtattc
    13981 aacgtactag gagatacgat cgatttagaa acacctttcc cagaagatgc ggaaagaagc
    14041 gaaattcata aaaaagcacc agcctttgac gaattaagta caagtacaga aattttggaa
    14101 acagggatca aagttatcga tttgcttgcc ccatatttaa aaggtgggaa agtcggacta
    14161 ttcggtggtg ccggtgttgg taaaaccgta ctgatccaag aactgatcca taatatcgcc
    14221 caagaacatg gtggtatttc tgtatttacc ggtgtaggtg aacgtactcg tgaaggtaat
    14281 gacttgtatt atgaaatgaa agattcagga gttatcgaaa aaacagccat ggtgttcgga
    14341 caaatgaacg aaccaccagg tgcacgtatg cgtgttgctt tgactggttt gacgattgcg
    14401 gaatatttcc gtgatgtaga aggtcaagat gtactgttgt ttatcgacaa cattttccgt
    14461 ttcactcaag ctggatctga agtatcagcc ttgttaggac ggatgccttc tgcggttggt
    14521 tatcaaccaa cattggcaac agaaatgggt caattgcaag aacgtatcac atctacgaaa
    14581 aaaggttcga tcacatcgat ccaagcaatc tatgtgccag ccgatgacta cactgacccg
    14641 gcgccggcaa cagcattcgc ccatttggat gcgacaacca acttggaacg taaattaaca
    14701 gaacaaggga tttatccagc ggtagatcca ttggcttctt cttcaagtgc tttagcacct
    14761 gaaatcgtgg gagaagaaca ttataaagta gcaacagaag tccaacacgt attgcaacga
    14821 tatcgtgaat tacaagatat cattgctatc ttaggtatgg atgaattatc cgatcaagaa
    14881 aaagtgttag tttctcgtgc ccgcagagtc caattcttct tgtcacaaaa ctttaacgtg
    14941 gctgaacaat ttactggtct tccaggttca tatgtccctg tagaagaaac agtgaaagga
    15001 ttccgcgaaa tcttggaagg caaatacgat gatcttcctg aagaagcttt ccgaagtgtt
    15061 ggccgaatcg aagacgtcgt agaaaaagcg aaaacactag gctactagaa aggggtgccc
    15121 catggatcaa tatttaacag taaatgtggt aactcctgcc ggtttggtct atgatcacca
    15181 tgcagctatc gtcgttgcac gtacgacagc tggtgagctt gggattttgc ctaaacatgc
    15241 accaatcatc gttccattga cgattgatga agttcgtgta aaacgaacag attcagatac
    15301 ccacgtcgat tggatcgctg ttaatggcgg aatcatggaa gttcgtgata atgttgtttc
    15361 aatcgttgct gatagtgcgg aacgtgaacg tgatatcgat gtatctcgtg cggaacgtgc
    15421 aaaacaacgc gcagaacgcc aaatcgaaga agcaaaagca aaacaagata cgaacgaatt
    15481 gaaacgggca actgttgcgt tgcaccgagc aatcaatcgt atcaaagtat ctaagcactc
    15541 ataaaatgag atgcggatgt ttatccgtgt ttaagaacag taaaaagagg ttatgacaga
    15601 agtggtcagc ttcaagacat aagaaggaat ttacgaaaat tgcttctcaa atttttgtga
    15661 aatctcagct tatttttcga agaagctact tctggaacac cgtatatcag aggttgtgaa
    15721 atcagcgttt tgtcctgagt attagagaaa caaatggaaa atagttcctc atattttgcc
    15781 gttttttgag ctaataccga gggtcagatg attgaacacc gtttatttgg aataagggac
    15841 tgcgacaaga cttttgtctc agtccctttt tttgcatatt tttagcattt atttcctaaa
    15901 aaatgtaagg ggattcctat atttttaagt atacttgttt ttccttttat acattttatg
    15961 gtattatcat tttattagtt attataaaac aatcgttaga aaggacgtca ttatgcaagt
    16021 atacggaatt gatgcggtgc ttcgaatcgt gagtcatttg gcgtttatct acttagcctt
    16081 ctggtcttta cgttcgttac gcattgaaac ttttttcaga ccaatgcata atacgcaaat
    16141 tagaatggca atcgtacttt tttcaatttt tttagggtac actgcaagta attttttctt
    16201 agaagttatc gctttatgcc gaaatctttt cgttagcctg taaattttaa aaaaaggtac
    16261 tattttaaaa gcaaggatgt tataatagaa aagattttga gtaagtgtat gctcattgga
    16321 attttttgga gggaacaaca tggaagagat catcgtaaga ggtggcaatc aattaaatgg
    16381 aacagtaaga attgaaggag ctaaaaatgc tgttttgcct attttagctg ctagtttgtt
    16441 agcagaagaa ggtattacga cattagacaa cgttccgatt ctttctgatg tcttcactat
    16501 gaatcaagtg attcgtcact taaacgtaga tgtagatttt gatgaacaaa agaatcaagt
    16561 aacaatcgac gcttcaagac aattagaaat cgaagcgcct tatgagtatg ttagtcaaat
    16621 gcgtgcttca atcgttgtga tgggtccgct acttgccaga aatggacatg caaaagtagc
    16681 tatgcctggt ggatgtgcga ttggtaaacg accaatcgat ttgcatttaa aaggatttca
    16741 agctttagga gcaaaaatta ttcaaaaaaa cggctatatc gaagcaattg cggatgaatt
    16801 gatcggtaac acgatttatt tagatttccc tagtgtgggt gctactcaaa atatcatgat
    16861 ggctgccgta aaagcaaaag gaacaaccat cattgaaaac gtagctcgcg aaccagaaat
    16921 cgttgattta gcaaacattt tgaataaaat gggcgctcaa gtctatggag ctggtactga
    16981 aacaatgcgt attgaaggcg tggatcattt acatgcagtc aaccactcaa tcgtacaaga
    17041 tcgtatcgaa gcaggtacct ttatggttgc tgctgcaatg acacaaggca atgtgctgat
    17101 tgcagatgct atctctgaac ataactgccc attgatttct aaattgatcg aaatgggtgc
    17161 agaaatcatt gaagaagaag gcggagtccg tgtcatcgga ccaaaacata tcttacctac
    17221 agatgtaaaa acgatgcctc atcctggttt ccctacagat atgcaagctc aaatgacagc
    17281 tatccaatta gttgcagaag gtacaagtgt ggtgactgaa acagtgtttg aaaatcgttt
    17341 ccaacattta gaagagatgc gccgtatgaa cgctcatgtc aaaatcgacg gaaatgtagc
    17401 aatcatggat ggaaaccatg aattgcaagg tgcagaagta tatgcaacag acttgcgggc
    17461 agcagcagca ttagttttag ctggcttgaa agcaaatgga atcacacgtg tgcgtaactt
    17521 gaattatcta gaccgtggat attataattt ccatatcaaa ctacagcaat taggtgcaga
    17581 cgtcgaacgt gtagacatgg atcaaacttc tgctgaaaaa acagcacaaa cgattgctta
    17641 aggaagtggc tgaatgagta accaacgata tatcttatta actttgataa agattttagt
    17701 ggtgatctta ttgcttatcc ttctttttgt ggccggaacg atgatcggat atggtgtcat
    17761 cggtggcggc aatccattta aagtattcca gccaagtttg tggattcata ttcgagactt
    17821 ttttcattga taaataagaa tcacagtggt tctagtcgat atgaagtgag ccatgaagca
    17881 gaacatgata aaagaaaaca gaagggaacg ttgacgttag tcgcgatccc tttttttagt
    17941 aaaagaaaag aaggaatcta attgatgaag aagatattga tttatttagt tagaggatat
    18001 cagcgcttta tttcgcctgc atttccacct agctgccgtt attacccaac ctgttccaat
    18061 tatatgataa aagcaattca aacccatggt gcgctaaaag ggacggtaat ggggactgca
    18121 cggatcttac gctgtcatcc ttttgtcaaa ggcggtatcg attatgtacc attgacattc
    18181 cgattaacgc gaaataagaa agataaaaaa gaaccagatt ataaaaaggt tgtgaaaaat
    18241 acgggtagca ctgagcgata aagaaaaaga ggaaatttat tgtcaaagta acaactccgc
    18301 aactacttat atgggggaca aaaaatgatc gaagaactaa acaagaaaga tttaccatgg
    18361 tccttgttat tagatgcaga tcctgataaa gaaaaagttc aagtatatgt ttccagaggg
    18421 agtggctgga tatggaaaga aaaagaaaaa acaataggtg tactgatcta tgtggcaagg
    18481 gaaaaagaat acgaaatcgt caatgtagca gtaaccccaa cgtatcaagg aaaggggatt
    18541 ggcggaaaat tacttgagac agcttttcag aagctttcac agctagcttc aaaccaaact
    18601 cggatcatta tacgtactgg cactactagt agcgctgcgt tacacctcta tcaaaaaatg
    18661 ggctatgtgg agattggtcg agtcaaagac tattttatcc atcattaatc tgagcccatt
    18721 tttgaaaatg gagatcaatt aagggatcaa gtgattttag caattcactt acctaaaaat
    18781 agctttaact aataaacttt caattcgaga aaatgctttc aaatgctaaa tagatacatt
    18841 acaatagctt tagcaaacaa aaaggagaat atttttatgg gaatattagt ttttgatttt
    18901 ggtggatcgg ctgtcaaata tggttgttgg gatggcaaag agattaaagg taagggacaa
    18961 tttgcaacgc ctgaatcttg ggaagaaatg aaaacgcaat tatttcaagt ttataaaaaa
    19021 atactcgttt cttttgaagt cgaaggaatt ggaatcagct ctcctggagt agtgaataat
    19081 gagaaacagg tgattgaggg aatcagtgcg attccttata ttcatggatt taatattttc
    19141 cgagatttgg aaactctgtt tcaactccca gtaacgattg aaaatgacgc caactgtgcc
    19201 ggaatggctg aattttatga aggtgctgcc cgtgattatc aagatgttgc ttttgttgtg
    19261 gcaggaactg ggattggcgg ggcgttgttc acgaaaggac aaataaataa aggggcacat
    19321 ctttacggtg gagaatttgg gttgatgttc ttagatggcg ataagacatt cagtaaactt
    19381 ggtacagcgg tacagatggc ttggcgttat tgtgaacgca aaggtctcga taaaaatgct
    19441 tataccggaa aagatgtctt tgaattagca gaaactggag atgcaatagc aaaagaagaa
    19501 gttgagagtt tttatacgta tcttacaaag ggattattca gtattcaatt ttcgtttgat
    19561 ccagaagtga tcgtattagg cggcggggtt tctgcaaaag aagggctcat tgatgagatc
    19621 aaaagccgaa tgaagaagct gacagaacaa ttcgatctgc atgatttcga accgcagatt
    19681 ttattatgtg agtacagaaa cgatgctaat cttgtaggtg cagcagcaaa ctatctcgct
    19741 gtacgtcaag gagagaatta agagctttag agaaggtgca gcttgcataa aagaagagaa
    19801 tgaaatgaat aggagatttt tacctaagga atgttttatt tgctgcagta tgataaaata
    19861 tctgagaggt gaaaatgatg tcaaaaaaaa ataaagatat tgaagtgcgt atagaagaag
    19921 tgaaaaaaga tatcaaaggt aagaattatg aagtcactca gttatttata gggaaaaaaa
    19981 tgattggtga gatcttagcc tatgggccaa aagaatatga aattttcttt ggtgaagaag
    20041 attttggaaa agaaaaaagt cttgaaaatg cgatagaaac agtgattcga cactggaatc
    20101 tgcacgaata aaaaaatatc aaaaaaactt tcaataaagg gttgcaaaaa tctggaaaat
    20161 taggtattat aactaagtca ggttgataca aacctttcgg aggagtagcg aagtggctaa
    20221 acgcgacgga ctgtaaatcc gttccttagg gttcagtggt tcgaatccac tctcctccat
    20281 ttcattgggg tatagccaag cggtaaggca agggactttg actccctcat gcgttggttc
    20341 gaatccagct accccagtat
//
LOCUS       DAFEEZ010000051        20069 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000051
VERSION     DAFEEZ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.053"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(266..1633)
                     /gene="nhaC"
                     /locus_tag="LP245_001996"
     CDS             complement(266..1633)
                     /gene="nhaC"
                     /locus_tag="LP245_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBL1519897.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1742..3163)
                     /locus_tag="LP245_001997"
     CDS             complement(1742..3163)
                     /locus_tag="LP245_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1519898.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(3406..5283)
                     /gene="tdc"
                     /locus_tag="LP245_001998"
     CDS             complement(3406..5283)
                     /gene="tdc"
                     /locus_tag="LP245_001998"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBL1519899.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(5574..6830)
                     /locus_tag="LP245_001999"
     CDS             complement(5574..6830)
                     /locus_tag="LP245_001999"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBL1519900.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(6942..7147)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7410..8711
                     /locus_tag="LP245_002000"
     CDS             7410..8711
                     /locus_tag="LP245_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBL1519901.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(8780..9379)
                     /locus_tag="LP245_002001"
     CDS             complement(8780..9379)
                     /locus_tag="LP245_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1519902.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            9633..10514
                     /locus_tag="LP245_002002"
     CDS             9633..10514
                     /locus_tag="LP245_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519903.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            10527..12137
                     /locus_tag="LP245_002003"
     CDS             10527..12137
                     /locus_tag="LP245_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBL1519904.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(12214..12873)
                     /locus_tag="LP245_002004"
     CDS             complement(12214..12873)
                     /locus_tag="LP245_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL1519905.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(13156..13821)
                     /locus_tag="LP245_002005"
     CDS             complement(13156..13821)
                     /locus_tag="LP245_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBL1519906.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(13968..14573)
                     /gene="dhaL"
                     /locus_tag="LP245_002006"
     CDS             complement(13968..14573)
                     /gene="dhaL"
                     /locus_tag="LP245_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBL1519907.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(14601..15611)
                     /gene="dhaK"
                     /locus_tag="LP245_002007"
     CDS             complement(14601..15611)
                     /gene="dhaK"
                     /locus_tag="LP245_002007"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBL1519908.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(15586..16032)
                     /gene="dhaM"
                     /locus_tag="LP245_002008"
     CDS             complement(15586..16032)
                     /gene="dhaM"
                     /locus_tag="LP245_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBL1519909.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            complement(16071..17030)
                     /locus_tag="LP245_002009"
     CDS             complement(16071..17030)
                     /locus_tag="LP245_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1519910.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            17200..17520
                     /locus_tag="LP245_002010"
     CDS             17200..17520
                     /locus_tag="LP245_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBL1519911.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(17632..18501)
                     /locus_tag="LP245_002011"
     CDS             complement(17632..18501)
                     /locus_tag="LP245_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL1519912.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(18597..19901)
                     /locus_tag="LP245_002012"
     CDS             complement(18597..19901)
                     /locus_tag="LP245_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL1519913.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEDTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(19898..20059)
                     /locus_tag="LP245_002013"
     CDS             complement(19898..20059)
                     /locus_tag="LP245_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519914.1"
                     /translation="MKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
BASE COUNT         5723 a         4146 c         3663 g         6537 t
ORIGIN      
        1 aatacgctga ccatttatcc tatggtcagc tttttatgta aaagaagata ctacttctaa
       61 cacattgttt atctgtaaaa aagagcgtgg gacaaaagta aagaacactt ttgtctcacg
      121 ctctaaacac gtataaacgg cggaagcaga agcaactcct tcggaaataa gctgaaattc
      181 acaaaaattt aaaaagcaat tttcttgagt ttcttcttat ttcttggagt taaacgcttc
      241 tgtcccagcc tcttttttcc ttccttcaat tttttacacg tcgacgattc aataaaaaac
      301 cgcctaatat tgtaaagaca ggtgcaagaa tcgagaaaaa ggcgaatggc aagtaatgca
      361 acgcgctaac tttcatcgtt cccataatga atgtgccgct gactccccac ggtacgagag
      421 aattgacggt cgcacctgaa tccgctagtg ttcgtgtcaa ataggttttt gataagccaa
      481 cgtcatcaaa agaacgcttg aatgtttctc ctggaagaat gatggacaga tactgttctc
      541 caacgatcag attgattccg atacagctca aggcagtaaa cccgactaaa cgagaaggtc
      601 ggtccatctt ttcttttaat tcttgaacga tggtatcaac gatcagatat ttgatcagta
      661 acccacctaa tgccaatgca agtaaaatca aactagcaga acctaacata ctcatgatcc
      721 cgcctcgaga aagcagttca tctagctttg gatcaggtgt atttgcgaca taaccattca
      781 tcaagatgtc tgctgctttt ccgaccgtca aacttttctc atggataaaa gaaagaacga
      841 gagcagctgt cgatcccgct agtaatgtag ggatagccgg aatttttttg attgcccccc
      901 caaataaaat aactagtgga atcaatgtcc aaggagagat ccaaaagctc gctttcatgt
      961 tttggatcat ttcattgata ctagctagat cggctgaatg actgttatgt cctaatatcg
     1021 tataaaaaat caacgaaagg acgaatgctg ggaaatccgt ataacgcata ccagcgatat
     1081 gttcgaatag attaactcct ccaatacccg ctgccaagtt ggtcgtatct gataaaggcg
     1141 agcagttatt ccctaaaaag gcaccggaaa cgactgcgcc tgtagtcatt gcatcattga
     1201 atccaagtaa atgaccgatc cccaaaaaag caattccaat cgtcgaaatc gttgtaaatg
     1261 aactgccgac agtcactccg acaattgcac aaacaagaaa tgctgtcggt aaaaagaaac
     1321 gcacagaaac aagtttaaat ccataaacca taatcgtagg gatggttcca gataaaatcc
     1381 atgaagcaac taagacacca atcaaaagaa aaatcaggat tggaatgatc cctggagtga
     1441 ttcctttgat gatcccgtca tggatctcat cccatgtgaa ctttttaaat ctgccataaa
     1501 acaacaaaca catgaaagct gcaaggatcg ggatatgtgg cgagagctgg aatccgatga
     1561 tcagtactcc taggagtgcc aacaacacga tcaatacagc gatactttct tttaaagaaa
     1621 tatttttatt catcgtcgat ctcctatttc aaatgaaaag gccctgccat gaaaaaacta
     1681 ttcacttggc aggacctcct actaaatcag cgacaaaacg tcggctgaaa gacttatttt
     1741 tttatttttc ttctaaactt ttttctacct caatccccca agaatctttc ttgaagtgat
     1801 tgatgatcaa tggaataacg aacatgacca ctgtgatagc tgctactaat aatgcatcac
     1861 tcaatgtcgc tgtacctaat gtagcaaata cgacaacgat gatagagaag atcagcatgc
     1921 agctgactac ccaagctaat ccgtttccgt ttttaccaat tcggtaagga cgttcgaatt
     1981 ctggatgttt cttacgcatt ttaagcaatg aaacagcaat caaaatgtac acgatacaat
     2041 aaataacagt tgtagcattt gtaagtgtca agaatacagc acttacgtca tccattacac
     2101 cataaagcaa agcaaataat gaaataacga ttgattgtgt tagaacgaca tttctagata
     2161 cgccgtattt gttttcttta tggaatccga attttggtgg aaggaatcct tcacgagcta
     2221 cttggatgat tgtttttgat ggtccagtaa cccaagctga taattgtaaa agcacaccaa
     2281 taaataccat gaagctgaag atatttccga tcacttctgg taagcctagg atttgacagt
     2341 caatcaagat aggctgcgtg atatttgcta attccatttt tccatctggt acgacatttg
     2401 ctacaagcat cgcattgatg acattcaata aaactaatcc gatcaaagcg ataaatacgc
     2461 cttttgtata attttttgtt gcgtctttca aacgaggcat gtaaacagaa ctcatttcga
     2521 tcccaacaaa aataaatgtg ataccagcta agtatttcaa tgaatcaata tgttccaagt
     2581 cagggaaagc ttttgaccat gaaaagtcac ctagatagcc gtttgagact agtccgactt
     2641 tgaaggctgc caaaacacct aaaacgaaca tgatgactac tgggatatat acccctagcc
     2701 atacaccgat gttcccgccg acttttgcca tatcgaattt caagttcaag atcgtgatga
     2761 tccagtagat aactaaaata caacctaaaa cgaaccagtg attattgcca agttctacat
     2821 taccaaatgt gtttcctaac aatggtccta aagtagaagc gaccattacc atacctggga
     2881 acatttgcac ccataatagc catgcaacga caaatcccca tttgctgccc agtgctgttt
     2941 ttacccataa ctgaggaccg ccttcttgag gaagcatcgt ggaaagctca ccggaaacca
     3001 ttgatatcgg accggcaaaa aacaaaactg caaaaattga ataaaaaatc aatgtccaac
     3061 cgactgcggc taacgtagga atactccgaa ccgttgcaca cagtgccatt gtcagaccga
     3121 taaaggtccc aagacccatt ttacttactt cagatttact caccgttgac actctccttg
     3181 attttttgga taaaataacg gtgtctttga agtagtttca gcaataaacg aaacaattca
     3241 gcgaatattt gaggggattc tttgagttta ttgcttgaag ggtttcttca aagacaacct
     3301 caaaacaaag ggatcgaaga gcttaggtct ccccttgctc ttcagatcca aacatgcgtc
     3361 agaaacagtt agtattcaag ctgttttcta acatgattac cttgcttatt ttgcttcgct
     3421 tgccaataat tggtctgcgt agattttttc caatttttct tgaagagctg ctttgatttt
     3481 ttcagcatat tcttcaaagt gttcttcttt gttcatgtat ggtgtcatta cgctggcacg
     3541 caatacagtt acttttccgg cacggttcca ttcttcatct gagaatccta gttggttcac
     3601 aaattgtaat gggctgttgc catagtctgg gatagcaaag tcagtatgtg aagttaagaa
     3661 ctcattaccg taaatgcttc ctttcacgta tgaagaataa tcatatacgt catggttcaa
     3721 tttattcatt gcaactaagt catcgttgcc tttttctttg aatacatagt ctaccatatt
     3781 gaaatctgga taagttaatg gatgaacttc gatttctttg tctcctactt taaatgacaa
     3841 gtcattcaag aagttgtaga aacgatgtgc accttcgatt gatgcaccca ttaatttacc
     3901 atatcctgtg acattcaaag gtaagacatg gtgtgctgcc caaacgctgg ctgctgttgc
     3961 ccctgctttt gaaccttcca agatataagc cccaagtaat gctgggatat ctgcgccttt
     4021 ttcaaataca tatgtcgcaa agtaagagat aacgtctctc atgcggatat ctttgatgac
     4081 gataccaccg gcagaatatg gaacatagcc cattttatgt gggtcaatcg ttacagattc
     4141 tgcttcttcg attgctttat atgcactgtg tacttcttct aagatataat ctttgttttc
     4201 tgtaaagaca ttgtatttgt aatgaacatc ttttaaatct tcaaatggaa tgaagttgtt
     4261 gtcttcgtct aagaaaatcg cacggccgta tccgccataa gcagcatcta cgtgtaagta
     4321 gaagtaaata ccgtcttttt ctaatacgcg acgcaatgca acgattttat cgataccgtc
     4381 gattgctcct tcttctgttg atcctacaac accgactaca cctaggattg gtgttttttc
     4441 agctgctaga ccacgaacga ttttttcaag ttcgttgatg tccatgcgat agttgtggtc
     4501 aactggcact ggaatcactt ggtctaaacc gataccgatg atgtcggcag cttttagcca
     4561 tgaatagtgt ttagtttgtg gaaccaacca ttttcctaat ttttctaaat gttttccgct
     4621 acgtgctgag tgagctttga tttcgtcgat tttttctggg acgctgtcta acagattcat
     4681 gatttcttct gttgacaagt tcattaattc ccaatcgctt tttccagcaa ctagttcagg
     4741 tgtcacttct ttcattgcaa gcggcaatga tttgatgttg cgggcatacc aaagtccttc
     4801 taagtttgct aaagaaccat cagcaacgat gtggccccag ccatctttat agctcattaa
     4861 ttttgcaaat tccattccta cttcttcttc catttggctt gttgcaggag aagattcata
     4921 ggcaacgtta ttaccattcc atagcatagc aaaattgtac gctagtaaag atggcatcaa
     4981 tgtttcagag ttcatatgac cccagtaacg tccggcatta tgccaaggaa cggaatgggt
     5041 acgcatccgc gctgaaattt ctgatagaac atcctttgtt ttattcacag tgtgttcaaa
     5101 actagcactg cttttttctt ctggcgtaat aataggcatg tcttgaggca tgtagttttg
     5161 acgccagcct aaatgttcat ccaccaattc attcaacaaa gctttataga tttggccgtt
     5221 ctcagctttg tccccaatga atagggcatt taggtttaga tctttcgaca atgattcact
     5281 catagtgaaa ccctcctaaa aaaatattta aattttgtcg agccctacat tacacctgtt
     5341 cttctattct gtaaactaag ttttggcctg atttttaatc atattttaat atgtatcaat
     5401 tatccgaatt gttcacactt ttgaaataat taaaaaaaac gagggaattt acaaatgtaa
     5461 actccctcgc aaagattgta ttaacgacaa ccagcgttct attttaggat gggtttcaaa
     5521 attggaatgt tgtaatagta tttccctttt tcaaggtaaa aacttactaa attctaatca
     5581 attactttgg ccaaaaagta atttttctta ccttttcgaa taaccacaaa cttaccatcg
     5641 aattcatcgg atggatttat gacaaaattt aaatcggtaa cgcggtcacc gttaatactt
     5701 atagctccgt ttgaaacatc ttcacgtgct tgacgtttag atggttcaat ttttgtggaa
     5761 acaagcagtt ccacgatatt ttcaggtgtg cttgaaattt caacgttcgg cattttaccg
     5821 aatccttgcg cgatttcttc cgcatttagt tctttaatat ttccagagaa caatgcttgc
     5881 gttatttttt gcgcttcttt caagtcttct tcactatgca caaatcttgt aacttcttct
     5941 gccaaacggc gttgtgcttc acgtttctca ggttctgtct ctactttttt cgctaagtct
     6001 tcgatttctt cttgagacaa gaaagtaaag aatttcaagt atttcactac atcgcgatca
     6061 tcttgattca accagaattg gtagaactca aatggtgaag ttttcttcgg atcaagccaa
     6121 acggcaccgc ctgcagtttt tccgaatttc gttccgtcag ccttcagcat caatgggatc
     6181 gttaaaccga acgcttctgc ttctggtcct tctaattttc ggattaggtc taatccagct
     6241 gtgatatttc cccattggtc tgctccaccg atttgcaatt gcacatcgta tgttttatgc
     6301 agatgcaaaa agtcgataga ttgcaggatt tggtaagtaa actctgtaaa tgagattcct
     6361 acttccaaac ggctggcaac gatatctttt gctaacatcg tgttgatgtt gaagttttta
     6421 ccgtagtctc tcaaaaattc aagtaaagag atttttgaca accagtcgta gttgttcaca
     6481 aatgtgatat ttgcatcttt accaaacaat tttctcattt gattggaaag tgcgtccacg
     6541 ttatgttgca cttgttccat cgtttgcaac acacgttctg ttttgcggcc gcttgggtcg
     6601 ccgatcgttc ctgttccgcc gccaatcaga atatatggat gatggcctgc caattggaat
     6661 cttttcatca tcataaatgg aatcaaatgt ccgatatgca tcgaatcacc agttggatca
     6721 acgccgcaat aaagtgaaat gctcttttct tcaacgagct cgcgaagtct ttcttcgttt
     6781 gtttgctgat taatggcgtc gcgccaagtt aattcatcaa taatattcat tttactgacc
     6841 tccgtgtagt ttttttatga aagcaggaac ctgctagcat gtgtaattaa ttatttcttc
     6901 aggataggat aggaaataaa aaaagtccct tggcatataa gccaagggac gaaatctcgc
     6961 ggtaccaccc aatttgtatg tctagatatc caacatacct ctcgaacatt taacgctgtc
     7021 gcgtggcaat cactgccaaa gactcctgaa atgtaattcg ctttaaagca tgtactggtt
     7081 tgcagcgacc accagctttc tgaaacattg gctttaacaa ctacttcgtt tcgatcttcg
     7141 tcttgttatt attaatatgt gtctatcata gagcgcaact ttttctttgt caacagaaaa
     7201 aggatatttt ttttaaattc ctcatttttt cttttttgaa tccgctctaa ttccgaacat
     7261 tttattttca attattgtta aaagaaataa ctttttctgt attttttctg caatttatcg
     7321 agaagtcact ttactttgcc tcttattctt tcttcgttac aataaggaat gggacaagta
     7381 aaaaaatgaa aaagcaaggg acgaggtata tggaaaaaaa gcaaaaaatt attttaggag
     7441 ccacttctgc tttaactatc gttattttaa ttctaagttt gttttttgtc atccgatcat
     7501 ctacaaaaaa agaaccaatc attcctgaaa aaaaaataac agaaaaagca aaagaaccga
     7561 cagatgataa gcaacaacta gttactcaag caaaaaatct ggctcaaagc tacgattatg
     7621 accaagcgat tgcgttattg gaaaaagata gtaagaacgg atctactgaa acacaacagc
     7681 ttcttcaaac actaaaaaag gagaaagaac aactgatcga ctggtctgat cctactcaga
     7741 tctctcatgt ctttttccac agcttgatcg tggacccgca aaaagccttc cactctcaac
     7801 aggcacaagg atacaaagat tatatggtga ctgttgaaga attcaaccgt tcgatcgaac
     7861 aactttatca aaatgatttt gttttagtta atttgaatga tttgatccaa aaagacgaac
     7921 aaggaaatct ttcctttaac gggcttgcgc tacctgaagg aaaaaaacca ttggttcttt
     7981 cacaagatga tgtcagctat tatgaatata tggataattc cggttttcct agccgattgg
     8041 tcgtatcaaa taacaatgaa atcaaaaatg tctataaaga gaaagataaa gaagaaatcg
     8101 gtgactttga catggttcct ctgatcgatg cctttgtcaa gaaacatcct gatttttctt
     8161 atcgaggcgc aaaaggtacc ttggccctga caggttacaa cggagtttta ggttatcgaa
     8221 catcaaaatc tcaatatgga gacaatgaaa aaacaaaaaa agagattaaa gaagctaaaa
     8281 aagtggcgga acagttgaag aaagacggct ggagctttgc ttcccataca tggggtcact
     8341 tgaatatgac tcaagcttca ctagaagatg taaaaaaaga caatgaattg tggcagcaag
     8401 aagttgcacc tatcctagga aaaacaaata ttctgattta tccatttggt gcagacatca
     8461 gcgactggca gccttattca gcagaaaatc aaaaatttgc ttacttgaag agtcaaggtt
     8521 tcgatatttt ctgtaatgtc gatgcttcta caccagcttg gggacaatta ggtacggatt
     8581 tctatcgaaa tgctcggatc aatatcgatg gcattcgttt tcaatctgat ttagacggaa
     8641 aaaatcctat tcttgatcca ttcatcaatg tccatgatgt ctatgacaaa gaagcacgcg
     8701 aatctgcttg attttacgtc atttatgaac caaaaaagcc gaactgacat tttatcgtca
     8761 gtttcggctt ttttatgctt tatttcttct tcggtgcgat tcccttgatc aggacttctg
     8821 tccattctgc tgtatatgga agcagttttg cgtatatctc cggcttagaa attccttcta
     8881 ccattgcttg aaaatagagg atcaagaact catccgaata tttcaaatcc acttttcctt
     8941 ctttccgccc tcgatggaaa agatcaagca tgatactgaa actttcttgc gtatacgcat
     9001 ccatcgcgtc agaaaattct tttttttctt tttttgtata gtatgtcatc aaatcgatat
     9061 aaaattgttt gttcactcga ttgagataac ggattttgtt ttcactcatg gcaatcagtg
     9121 tttcttcaaa tggaagattt tccgcaatca acgctttcgc ttcttgccct aaatcattca
     9181 taaatgcaaa aaatacttca taaatcagcc cttccttgct gccaaaatat ttaaaaatcg
     9241 tcgctttact tacctgagcg ttctcagcta ccttatccat tgtcactcca gcggttccta
     9301 tgtctgtgtt catcaagtca aaagctgctt gtaaaatctc tttctttttc tcttgtgctc
     9361 tcttttcaaa accgttcatt tgtagagcct cccgtaattt taaactttta taatatatat
     9421 agttcaaatt tattctgagg tttattataa ctatctattg agaaagtatc aagctagcaa
     9481 ttccttgttt atgaattcat tgacagaaat ttataaaaag aatattatgt actaaaataa
     9541 taaaaaaagt tttataaaaa ggtataaaac ctttttatta aactatttaa tcttgtttag
     9601 tatatatttt tagaaaaagg agtggggttt ttatggcaga aatcgtcaaa gtcacacatt
     9661 tgaaaaagag ctttggtcgt ttcgaagctt taaaagatgt ctctttcacc gtacattcag
     9721 gtgaagtcgt tggatttatc ggaccaaatg gttctggaaa atccacgacg attcggacac
     9781 ttttagggat tataaaaaaa gacggcggaa cggcaacgat ttttgggcaa gatgtatggg
     9841 aagatagttt atctatccat gaacgtcttt cttatgttcc aggcgatatc tctttgtggg
     9901 gaaatttgac tggaggagcg atcatcgatc tcttcatgaa gcttcatgga aaagggagtg
     9961 ctcaaaaaaa agatgaactg attcaacgtt tctctcttga tcctaagaaa aaagcaaaaa
    10021 actattcaaa aggaaatcgc caaaaagtgg gcttgattgc tgctttggct gttgattcgg
    10081 atctctattt atttgatgag cctacttctg gtttagatcc tttgatggaa acgattttcc
    10141 aagaagaagt tgaaaaattg aaagaacagg gcaaatccat cctactttct tctcatattc
    10201 tcagtgaagt cgagcgacta gcggataaag tcgtgatcat acgcgaagga acactcgatg
    10261 aagaaggaac actcgatgaa ttgcgtcatt tgactcgttc gaccatcact atagaaacag
    10321 aagcagagaa tagtcactta gcacaattga acggtgtcca tgactttgtg caaaaaggtc
    10381 acctcgctca atttgctgct gataacgaag ctttcgatgt gattttagct gaagcgtcca
    10441 aattaggtgt gaaaaaattt gaatctattc caccgactct tgaggattta ttcatgagac
    10501 attatgaagg atgaggagga agcgaaatga ctgataaatt ttcacgctgg tccacccttt
    10561 tttctcaaaa ccttagccgt gactggaaaa agatcctgat atggctagtc ggtgtcactg
    10621 ctttttctgg tggttttgtc cctgcgtttg aagaattgac ttccggacaa ggattagctg
    10681 gattatacga aaccttgcaa aacccggcaa tgattgcaat ggtcggacca actccagctt
    10741 cgaatgctgc tgagtatact ttaggagcga tgtatgcaaa tgaaatgttg cttttttgca
    10801 gtttgtttgc tgctgtgatc tctgttttac acgtggtgag ccaaacgaga aaaaaagaag
    10861 aacttggtct gattgaactt attcgttcct ttcgagtcgg acgtcaagca aactctttag
    10921 ctgtcatcgc tgaaagtatt ctgatcaatt tgcttttagc aatatcgatc agctgtacga
    10981 tgattttttt ccaagcggat tcgatcactg cagaaggtgc ttggcttttt gggctatctg
    11041 taggtagtat ggggattttg gggagtgccg ttgcactgtt tgctgcacaa ctgatgccaa
    11101 gttcagccag ttcgaatggt ctgtctttag cgtttttagg tggactttac cttctacgag
    11161 caataacaga tgtagctgat tcctcccttt cgatgtggaa tcctttaggc tggtcttatt
    11221 tgacctatcc atttacaact aacaactgga ttcctttgct ttatttgttt ttgttcagtc
    11281 taatcttgat aatcagttca tttgttttag aggaacatcg agatttgaac accggctata
    11341 tccccgaacg tgaaggaaaa ccgtatgcta aacgttctct tttatccttg cgtggtttat
    11401 tattctatct aaataaaggg atgacaatca gttggcttat cacttttggt ttgatggggg
    11461 cggcatacgg ctctatctac gggaatatgc aacagttttt agaaagtaac gacttaatga
    11521 aacagatgtt tatccaatct ggcgtctcaa ttgaaaaaaa ctttacaagc acgatcatgg
    11581 tcgtcttgat ttgtctagct gctattttac caattgctag catcaatcgt ttatttacag
    11641 aagaaaccca cggacgtatg aatcagctgt tcgcaacaaa aatttctagg aaccaacttt
    11701 attggaccaa tatgttacta gctattctat ttgctatatt ggcaatcctg attagttctg
    11761 gtgcactagg gctttctgct ttggcttcga tgaaggatgc gaaagacatg gatctattga
    11821 tgtttcttaa agccgggttc aatttcctgc ctgccgtttt agtgtttatc ggaattagtg
    11881 gctttctatt cggatggctt cctcgaatcg gtaaacttgc ttatatctac ttagcttact
    11941 cctttgcact caattacttt ggcggaattt tggatttacc agaatggttt tccaaaacag
    12001 ctgtccctag ctgggttcca cggatgccaa acgattcttt tgatctttcc gtgttcctta
    12061 cgttatcatg tatcagcctt gcactgttcg tccttggttc tattggttat aggcgaagag
    12121 acttactaga aggataataa aaaagcatgt acaatttcat gctagcctcc aaatctgggt
    12181 caaaaatcca acatttggag gtcatttttt tatttacaag tcttctaact gctctttatc
    12241 aatgatccag acttctcgat tctttctttt tacataacca ttctcctcta ataatttaaa
    12301 ttttctagat aaagtttcgg gggtcgtacc gataaatgca gcaagttctt tcattttcat
    12361 tggcaggaaa aagtgatcct tccctgtcgc tttagctaag tcaagcagat agacagcgac
    12421 tcgttcttct actttttcca tcatcaaaaa agttgtctgc tgctgtactt ttgttaattt
    12481 ctcaacgttg attgctaaaa gtttcagact aagggcggga taatgcagta agagttccga
    12541 gaaatctttt tgtctcaata tgcaaatttc cgttttttct agtgcttcgc caaataaaga
    12601 ctcatttgga acgcctagca actggctctc tccctcatat ccgcccggct ctattactcg
    12661 taaaagctgt tcctttccgc tagcagataa ttgatacact ttcatactgc cggaggccac
    12721 gatcactaat tgaggttctc cattcggcgc aagaatctgt tctccttttt ccacatagtg
    12781 atgtttgaca agtgcgtgta ctttttcttg atcttgctgt actaagtgat tgaacaaagg
    12841 aacaaatgaa acacataaat gatcatgact cataatctct cctccttcta aacagctatt
    12901 tctaataaag aaacataact tcccttattc caactgataa ttttctttta tcatagcata
    12961 aacgtcaagc gaaccagata ccagcaaata gagtggattt ctttttgtcc cttgctttat
    13021 tttccttctt ttgagacctt aagtaattga ttcctatcaa ttttttaaat atttactttt
    13081 tgaataatca aaaacaaacc ttcactcgca agccgagagt aaggtttgtt tttcgcattg
    13141 cttatttcgt gttgtctatt gaaatttttc cgcacctagc ttttgatata gtggtgctag
    13201 ttcttgtaag gtttcagcgg ttatttgctc aacgtgttcg atttcttgcg gatagaagaa
    13261 tagtttaccc atttgaaagg ttcggtctct catcgctttt ttcaactctt cttgtttctt
    13321 tgtatcggac aaatagtcag acaaagctaa gtggtcgtca agttcatgtt ctggttgcgg
    13381 ccatatgtaa taatccttga tatcgactgt tttgctccac tctttcagta tcgcaagcaa
    13441 ctggttatac gctgcaatgc taccatatcg ttcttcgctt ttataatgtt ggtacatcaa
    13501 atagatttgg tattgttttt gattcaacaa aactgctaga caggcattct cgtcttgacg
    13561 agattcgctt cggtacgcgc tccaaaaatg actgcgtaaa ttccagccat tcgtccagct
    13621 ttcgatttta ggtttgctca tgccgtacat atcaggcaaa agtgcagctg tctggagctg
    13681 aatctctttc catttttgcc agtgttcttt atattctttc ttgatttgtt caatcttatc
    13741 tgttggatgg ctctctttga gctgtttgaa tgcgtagatt ggtcgatcaa acaactgata
    13801 atctgatttt ccaagttcca ttgtttcgcc tctttccgtt atcttttgta ttctacctga
    13861 attttgcgat atggacaaat agaggttgtg aaaaagctgt tctgcatcaa gtcataagaa
    13921 cagccaaaca aaaaactgcg atgagcatca ccgcagtttt attgaactta aggttgattg
    13981 atcacatcta aaagcgttga aaataaaatg gcactagaag cagctcctgg gtcgatatgt
    14041 ccgattgcac gctctcctag ataggaagct cgtccttttt tagctaccaa gactttggtg
    14101 tgttcttttg cctggtcaat gatttctttt gttaaattcc ctgccttcaa tgcctctgtg
    14161 actggcagcc aaacatctaa catcgtttta tcgtcagctt ctgcctttcc tcggctttga
    14221 atacccgctg ttccctgctc gatcacttcg cctaattttt cttgagaatc aatagaatcg
    14281 acctcttttg tcgctttcat catgttcatg aatgcagatc cgtataacgg accagaagcc
    14341 ccaccgactt tcgatatcat cgccatagag aatactttga atgtatcgct gattgtttca
    14401 ggatgatcgg cttgaaaagc ttcttcataa gctgaaaccc ctcttcccat gttatttcca
    14461 tggtctccat cgccaatcgg ggtatctaga tcactgagat attgtttgtt ctgattgatt
    14521 gcctctgcaa attgcgtgag ccattcttgg atttcttgaa cggttagttt catattatca
    14581 cccttttatc ttgagatttt ttaccatgaa atcgtctgta cattgctttc taaagaatct
    14641 ttccattgtg tctccgtcaa gtcgatcagt gttagagaaa gaccttgcat atctagtgag
    14701 gtcataaaat taccgacttt tcggaaaact acattgacgc ctctttcttc caacagagct
    14761 aaaacatcat tcatgaacac gaactgttcc atcaaaggcg tcccgcccat tccgttgact
    14821 agtacacctg cttcttttgg taaattcgag taatcatcta aaatcttagt aacaagttcc
    14881 tttgccagta ctttagaagg ctgcatcttt tctcgacgat agcctggctc accgtggata
    14941 ccaacaccat actcgatctc atcttctcct agttcgaatc ctggtttccc tacttctggt
    15001 acagttgctg ctcgaagcgc tagaccgatc gtcttagttg cctgtacgac cttttctccc
    15061 agttctttca actcagctag ggaagcaccg tttcttgctg catcgcccac gattttgtgt
    15121 acaaggacag tacctgcaac tccgcgtttt ccagcagtat acgtactatt ttcaacggcg
    15181 atatcatcat ctacgatcac actttctact tcaatatcgt ccatagcagc taattccttt
    15241 gccatatcga agttcaatgc atcccctgta taattcttaa cgatcagcaa aactcctttt
    15301 ccactatcgg cttccttaat agccgtctga atctgatctg gagttggaga agtaaacaca
    15361 tcaccaagca ccgctgcact taacatccct tcccctacaa acccggcatg ggatggttca
    15421 tgtccgcttc ctccaccaga aaccaaacca acttgttccg ctttctgatt cttggctaca
    15481 acacgggaag attctacacg atgaacaagt tctggatagc tttttactaa tccttccagc
    15541 atttcttcga caatattgct tggatcattc atgatttttt tcaatttatt cccatccttt
    15601 ctttccggca ttttgtgctt ctgttaagat ttgctgagta tcatctgtta taccggcagt
    15661 gatggctgct gcaaaagctc cttccactaa aggcgcatcc accagatgat aacgttgctg
    15721 ctgctcttct tccaacatgt cttttgccag ttccgagttc aataccgcgc taccgatatc
    15781 cgcaaaaaca aaataactag ctgcatcgct tgattcattg actgcttcta cgattttcat
    15841 cgggtctgat ccgatctcgc catttattcc gccgagagaa aaaatttgca cctcttcgga
    15901 tttttgcatc tgctcaatca tttctttaat accatctgtt actttttgac tatgagaaat
    15961 aagcaaaata ctttttttca caagaatctt cctttctttt acatagttgc taacgattgg
    16021 tttcgctttc attaatgaac aattcaagta tataataaat ttttcgtttg tcaaattaag
    16081 ctagacaaat catctttacc tacgtaactc aaaaatactt ccaatggtgt gcgatagtgt
    16141 aatgattttc taggaatatg atttcgtttt gatgccaccg attggataaa ggtttcggat
    16201 accttattaa aatccatagc tttatataag ccatctttac gtaataagcc attcgaatgt
    16261 tcatttagtc ctcgttgaga aggtgttcct ggatcagcga aataaatcga aatatcattg
    16321 gtattactaa tctttttcca attcgagaac tcttttccac aatcaaatgt gatggattta
    16381 aacaagtgtt tcggtacaga ttgaaaccat tgattcagtc tattctcaat atctatagct
    16441 tgcctaccag cgggtttcaa ggtgatgatc actttagata atcgctcaac taacgtgatc
    16501 accgcacttt tatgttttcc accgacaatg gtgtcacctt ctaggtgacc aaactcatga
    16561 ttgaactgta tataatcagt tgttctatcc tgaatcgaac ggcgaaaagc ttgttttcct
    16621 cttttttctt tatgtccgtt tggttttctt ttccctttca ttggtaaatc gtgagggtca
    16681 aaggttttat ctttaaacat ccgatatagt gtacgtaccg aacaagcaat aggaaactct
    16741 gctcgaccaa taaggacatc tggagtccac ccttgagcca cctttttttg aatgtattct
    16801 tgttgcccat ctggtaacac aatcggacgt cttccgcagt tacgtttgtt tttcttatat
    16861 tgttcatagt agcttattgc gcttccacca gatttaagaa aacgatagac attataaatg
    16921 gtttgtcgag aacgttgtac cagatgggct acttttgaaa cagagtgtga ttgattgaaa
    16981 taagcttcta tcattacgag ttcagttggt gtaagatggg tataggtcat ttgtactcac
    17041 tccttataat tctttcgacg gaactatttt gagtgtagca caaatgactt ttttagttgt
    17101 ctagcttaat tttacaatcg gcgatttcta attttgggaa aatatgtgta gtgcttcttg
    17161 aagtttgtta tactttaatt aaaagagagg agtgatcgaa tgattacaac aacaacgaac
    17221 agtgtagagg gaaaagccgt agtagcttat aaagggatcg tttttggtga ggtcattact
    17281 gggatccatg catttaaaga cttggaggcg gggttgcgaa atatctttgg cggccgctca
    17341 aaaagctatg aaaacgaact aatgggtgca agagaagaag cacttgccga aatggccgaa
    17401 cgtgcaaaag cattaggagc tgatgcgatc attggcgtaa aaatggacta tgaagtatta
    17461 ggcagcgaca atggcatgct gatggtcaca tgtagtggaa cagctgtctc cacgagataa
    17521 gtaggggaca tctgttttaa taactaaaga gagatgggac atgtagtggc actcaagaat
    17581 tagatttttc agtctaactt cgaggtactc taccttccca tcctctcttt tttatttctt
    17641 tttgcggatg attccgtaag ctgctgcgac taacacaccc gcccctgcta aggaataact
    17701 gacagaagct gttttttcat ttgtttttgg caaagtctga cttgttgatt tggatggctc
    17761 tgtcgtttgc tgaactgttt ctgtcgtgct tccagaggtc actgattttt ctcctgccga
    17821 atgcaaaata tcttttattc gttggaaact agctgctaag tcagcttttt ttgcttcaaa
    17881 atcattagca actgtttgtg cttcgctgat ctttccgtgg attgcttgac tggccgctgt
    17941 gatatccgct tgagtttgac ttagctttcc agaagctgtt tgagcaacct gatttaattg
    18001 ctgattgaat tcttttgctt gttggatctt cccgtcaaga tctgtttgga cagcttccgc
    18061 ttttgctttc gcttcggcaa gctttttctc aagttgtgca cggtcatttc ccactttatt
    18121 tttaagatca gctaaatctt gatcgattgc tgcttggtct tctttcaatt tgttttttgc
    18181 agcttctaat gcttcttcga gttcttttct tttattttcc aagtcttgca aatgatcgat
    18241 ttggtcagaa gaggtagaac tatttattga tgtatcttct gaagatgaaa tcgtttctcc
    18301 tgaattatct gtcggtacat tggaagtcat ttctgtttcc gaggcaccgt tttcagcacc
    18361 agaagagctt atggttgttg aaggttctgt ttgagcaggt tcagaagttt ccgcaaaagc
    18421 tgtctgtccc aataagaaaa tactggaaac agcaattggc cagattaacg gcttcattct
    18481 ttttttcatc acttttccca tccttactac tttttaacta atttcttatt ataagcaaaa
    18541 atgtttggaa gaaccataaa cacaacaggc tgtttgtcta aaaaacggtg catcttttat
    18601 ttttttgtac gttccgggct tttccatgtc ccgcttccat aacctaaaat cgttttgact
    18661 gctggaatga aagtcgtcac gatcgttatc gcgttcacta tccagaacaa aagcatatat
    18721 agtggtgcga aaagaaggta tttcaatttt cttcgtcgat catctacaat cagcgaagct
    18781 agcaactgga aaaatcctgc gaccatttca aagcagatga acacaaaact gaatgtaaaa
    18841 gtaatataaa tctgttcgta gtttccttga tatacataat gcccgattaa tccagcaaaa
    18901 agaactacgg aaatacaaaa gaatattgac cagacaatac tcaatgtttg atcaatgaag
    18961 atgatcgttc ttccaatatg tttaaaagga tggagcatca cttttttgaa attcgtcagc
    19021 cagacttctg ttccaccttt tgcccaacgt tttctgtgtc gatatagcat cttcaacgtc
    19081 acaggtactt ccatgaaaaa gataatctca ggagcaaaaa cagataacca gtcatttaac
    19141 tgatgatccc aagcaatact gatgtcttct gtcgctcgat cttgtctgaa tccgcccaca
    19201 tcgatcaagg cttcttttcg atacatcgta tttgctccac tgtacgcata aagaccaccg
    19261 aaaacagctg actgtgttcg tttaatgatg cccacgatac ttgagaattc aaccgtttga
    19321 gattttgcaa tcaatttggt acgattttgg acatccatat ttgcagtgac cgcagcaata
    19381 tgtcttgcac cagggcgaat gaaataattc acatacctaa tcagtgcatc tggctccggt
    19441 accgtgtctg catcattgct taaaatcaat ttcccttttg caaaggcaag tccgatatta
    19501 aacgcgtggg cttttccttt atttttttcg atccgaacca cacgaagatt agcgtatttt
    19561 ttcatcagtc tagctaatat ttctggtgtt tggtccgttg aaccatcgtc tgtcactaat
    19621 acctcatagt tgtgataatt caatttcgtc atcaaatact cgattgtatc ttcgatcaca
    19681 atttcttcat tatgggctgg caccatgatc gtgatgaacg gttcgacact caagggaaca
    19741 tctacccatt ctttttgctt atgtttgtat aaaaacacat aacaccagac accaataaac
    19801 catacaaatc cgcctaaaat cggataagaa acgagaaaaa aatacataat agacaaacaa
    19861 gtatctaaga ataaattacc tgtatgggtg attgagatca tttcagttcc accccatttt
    19921 ctttatacaa atctgcaatg aatgtcgtat ctagattttt ctcttcggag acagaataaa
    19981 aacggaccgt ttctctctct tcttttgttc caaaacgttc cgtatacact tcttcaagta
    20041 attcttgtct ttttttcaat ttttcatct
//
LOCUS       DAFEEZ010000052        19652 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000052
VERSION     DAFEEZ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.054"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            48..365
                     /locus_tag="LP245_002014"
     CDS             48..365
                     /locus_tag="LP245_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL1519915.1"
                     /translation="MKEARPRDEIDKLYKTKRWRDLRQVVIARDFGMCQECKRRGRNT
                     RGTIIHHIVEAREDLSLFWSVDNLECICVACHNREHPERSGGKKKPKPKSHIVKMYST
                     PER"
     gene            complement(523..687)
                     /locus_tag="LP245_002015"
     CDS             complement(523..687)
                     /locus_tag="LP245_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HBL1519916.1"
                     /translation="MGELYKPGEDNKPKGTYKEVGPRGGNVQGGQEVKIDPGDRLPPT
                     SQKGNKWTKK"
     gene            789..1310
                     /locus_tag="LP245_002016"
     CDS             789..1310
                     /locus_tag="LP245_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBL1519917.1"
                     /translation="MPQPAKSAKLQLLNGNPNKKNTEELRKRAAAEDKLKMATDKIKP
                     PLWLDSLGKDTFEFIADELLSVDLISNPDVHTMALYSNWYSQYVSLEKQLRKLQREYK
                     LNYALAKKEAEARGEPFNEPNELIGNPLSRQMDTASRNLRSFGADLGLSPAARAKLAI
                     KMADDGGDDDDDF"
     gene            1297..3087
                     /locus_tag="LP245_002017"
     CDS             1297..3087
                     /locus_tag="LP245_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBL1519918.1"
                     /translation="MTTSNILDMSYTERVDYWQSYLEEQASWGGFLKCPYPELLTTWY
                     AERLIDGSIPASKENIQAAKRHMRDLQRQGTDDFPWIFDEEKGHRPIRYIEKKCKPTE
                     GDFGSFVLQPWQHFIIGSMYGWVHRDTGERRFREALIFVGRKNGKTSLISGLSTYMVA
                     YDDEQGANVYVLANARDQASLLFDKAAEMVKQSPALFKKFGKPKRSSINYAPAFSKME
                     PRASDSRKLDGLNTHFGIFDEIHEFTNYNLINVIKKSRGTRKQPLIVYITTAGYVLDG
                     PLMSYFEQGVDCLEHLEDDIDERTFYYLAKLDSAEEADDPRLWIKANPNICLMNFVGM
                     LDDYVKDKKDPKEYADWITKQFNLFSDIDELSFVDMPTIKRNNKTIDIETLKGKKCVG
                     GFDLSETEDFTAAVLEFPLETGEVFILQHTWIPQARFDRDNNQERIKAWEKVGDLTII
                     PGDYVNYEYVLNWFVENSKIYDIVKINYDKAKALRLNKELENAGFETNEIRQGFLSLG
                     GPMQNFKEMLLDGKVIFNNSKLYRWYLSNVKLVMDRNSNWMPSKQSKSRKIDGFAASL
                     NSHAEVLNMLVNPVGTGKVTYYSISDLMNM"
     gene            3103..4323
                     /locus_tag="LP245_002018"
     CDS             3103..4323
                     /locus_tag="LP245_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL1519919.1"
                     /translation="MSILDRLRSFGRAKPKASKQEYFLNDPGLIPYLVGKDEISEGIF
                     SVISRVSNVFASLPLKMIDVEFGQPDDCPAYNLLSEGPRYFTKFDFFRDVEVLRNYQG
                     NAYVQIFRNINGEVADMALVKPGACHPVIDMDSGELYYQVTATDKGSYKQVIYVHYME
                     MLHFKQPRFGGLEGTDPTKVLTNTLGYDREVRKISLSQLKGSNEGLKVKFASNMDEEA
                     KKATVKNIADFYRQNGGLLVEENGVEIERLQRELVDSKLLDTDKVSRSRIAMVYNVPE
                     HFIGNNQSSYSSQEQLNMEFLTYNLVPTVNQYEAELNKKTLSRTEKAKGYRYKFNVAS
                     LLRADTQARGQFYQIMRRGGAYSANDVRRFEDLQPINKTGMDDYHISGDLYPIDMDPT
                     LRKTTSSKSVAENG"
     gene            4358..5035
                     /locus_tag="LP245_002019"
     CDS             4358..5035
                     /locus_tag="LP245_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBL1519920.1"
                     /translation="MKKVTLSGDVVDNDTAWLYDWFGINCISPGKISAALTEAAGDEV
                     ELDISSNGGDVLAASEIYTAIRAYPGKVSGNVVSIAASAASVIACACEPLRISPTAHI
                     MIHNAWVTTSGNAEELKANAEMLSSVDESIVNAYEIKTGLDRKKLADLMAKDTWLNAQ
                     TAVAEGFADEIMFAEAPVTVLNASQPVIPKNAVTKLKNLILKAEAPQEETLLQKKLKA
                     LNGGKNE"
     gene            5032..6225
                     /locus_tag="LP245_002020"
     CDS             5032..6225
                     /locus_tag="LP245_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL1519921.1"
                     /translation="MNLEQLKNAWVEAGSKVSDLNAQLNAALVDDEKTEEDVVSLQAQ
                     VKAARAKRDGLKEQVANMEAEQVLNVKKEPLDKKDENLKNKFIKDFKAMVNGDPAIMA
                     TLTSNTDESGNAIGLTIPVDVQTTIHTLVRRFDSLQEYVNVEKVTTTSGSRVYEKWSD
                     ITPLTALDTEDGEIPANDDPALYLIKYLIKRYAGISTVTNSLLKDTAENILAWLSKWI
                     AKKVVVTRNTKILAAIDGIKAAQKKDVTDVDGIKDIVNVQLDPAIEATSMFITNQDGF
                     NVLDKVKRADGSYLLQKDVASATGYTFLGKPIKKIASRFLPNKGTQATPKYPLYIGDL
                     KEAVTLYDRENMSLLTTNIGGGAFETDTTKVRVIDRFDVQLVDDEAVVLATFTTIANE
                     TPAKV"
     gene            6240..6566
                     /locus_tag="LP245_002021"
     CDS             6240..6566
                     /locus_tag="LP245_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBL1519922.1"
                     /translation="MILDPKMDLGEIKNALKIDTDDDDVEVSRAAQAAIAYIRGAIGN
                     DKPSFYKQENETVDLINLAILQLADHYYNARSATVSGNLREYDLGFTSLILQLKASYL
                     LFVEEE"
     gene            6570..6905
                     /locus_tag="LP245_002022"
     CDS             6570..6905
                     /locus_tag="LP245_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBL1519923.1"
                     /translation="MPLIQTGNLNQRIKFVRDTTVKDEDGQVVPTSTTILTCWASVQT
                     QRLNDIKTSIGTALEGTLTFIIRYQQKSELTNDMKVRWNGKTFEIITITKGEFAKDFT
                     TIIAKEVSK"
     gene            6902..7297
                     /locus_tag="LP245_002023"
     CDS             6902..7297
                     /locus_tag="LP245_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519924.1"
                     /translation="MSVEVDATEVYKALREVKANVQRVESPALRKAGEYAQEELRQNT
                     PYWDGTKSNGKRGSYMQEHAKNHVVTSSIKNGLVEVGYDKDVSWRMHFIEFGTIKQRP
                     KGFVQKTQKQIEKQVTQIIADEVKRRLGL"
     gene            7294..7665
                     /locus_tag="LP245_002024"
     CDS             7294..7665
                     /locus_tag="LP245_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519925.1"
                     /translation="MKTAVSQVYSILNSNEKTKNIDFYTNSVPESAQTVPSLPVGRIT
                     EISGNYEDFASNNPLTIQFNVQVDVWVSTMKEVDAFYFALDEVMRGNGWQCAYTEQTD
                     DEDLEGAKRIIKRYVANISLN"
     gene            7681..8241
                     /locus_tag="LP245_002025"
     CDS             7681..8241
                     /locus_tag="LP245_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1519926.1"
                     /translation="MATVGFESVIFGVKTGAGGTLKELVADKSKGGAIEAKITGLGAT
                     SNTTYASNVPFFIASKGVSSPKVTLDVADLMDNGIYSEIIGAKTVDGANVIGSETEAP
                     YVSVVMVTANKEGKRLFMGLTKGKFSHPDIDMKTAEDKGVELQPDSIEGEFISDERGY
                     VYLTAVESEGMTLQKFKDLVNNKEGE"
     gene            8366..8677
                     /locus_tag="LP245_002026"
     CDS             8366..8677
                     /locus_tag="LP245_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519927.1"
                     /translation="MIELQLKLDGKKKTFKQQDISARAMRECIKFYEKAEKADLTDLE
                     AIDSMIAITADIFQDPAVTFDAILDGLTASELVPALESVFEQINELGNNEKKQTASKK
                     K"
     gene            8701..8892
                     /locus_tag="LP245_002027"
     CDS             8701..8892
                     /locus_tag="LP245_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519928.1"
                     /translation="MDQIYKDLIEAGWTMRDVDEADYHYLLHLFGEVESGEEYVDGAD
                     FIKQFLSAEDLVKLEEGGK"
     gene            8892..12740
                     /locus_tag="LP245_002028"
     CDS             8892..12740
                     /locus_tag="LP245_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBL1519929.1"
                     /translation="MAGKGQPAGNIKLGISLDSTSFGNTLDEINAKVKQAESNMRANL
                     KAYDSAGRSYEALSQKTKDLSTVMEGQNAKVRELTKRRDEAISKYGEESKQVANLNTQ
                     INNATAKYNAYSRQLNDTKKELVYSKTAVNDLSNEIKENERQMNAEVKALKAAGDESG
                     AFEAKQKGLAKQTELSEKAIEEQRKVVKLMADEFGDSANETEDAKRALEKLERQSQIS
                     SRQLEALKSSSDQSGKEIEDFGDKSTRSARKLDGLKDKLSSLKSAFSFGAVAGLAHNA
                     ISSVVSGVQGLVGEAVNASDSLMKFSKTMEFANFGKSQIESSKKEMKDYADKTVYGLE
                     EILNTTAQLASNGIPNYTELTKAAGNLNAVAGGSSDTFKSVAMMLTQTAGAGKLTTEN
                     WNQLADAIPGASGLLQDAMLKNGAYTGNFRDAMAQGQITSDEFNQAIVQLGMNDGAVK
                     AATSTDTLSGSWEQMKSTVINGLQSIIEKIGVENITGFINRVTKGIENSIPKITQFIG
                     WLRDIGTWIVENREPLTWIVGIIGGITLAVKALNVASMLLAITGGTLAAPFVAIGVAL
                     GALAGALVIAYTKSETFRNIVNAAFTAVKNVVMSVINNLVEYYKMLWSVLQWLWEKIK
                     EWASWIGNKFIEMKNSVVNTVQNLWNGVKNFFSNGVGDTWNKVVGWVKNIFNKATELK
                     NNVSDVIGNLWNGIKDTFRRGIDTVFNWFSELPTKMKNAIIGGKNAIVDAFKSIFNAA
                     LKAIGKPVNAIIHGASWVLEKLGAEPLQEWDVPQYATGTPAGGHPINGPMMVNDGRGA
                     ETVITPDGRAFIPKGRNVVLNAPKGTHVLTAEETAQLQGSKAPKYRYKKGTNFFGNMW
                     DSVKKVAGNVGHTIKNVVGDVWDFISDPGALARKVLGGLDVLGGLTKYPLEVGKGILS
                     KATSALTEKITGLFSSGNLDTSVGTNGVYKYLADVAKSVMKKFPGFVATSGYRPGDPY
                     SHGKRNAIDIALPGVTGGSPRYTEAANYAFDKFASKIGYVITNGKVRDRSGQSGQPAT
                     GAWEPWPDGDHYDHVHLNGVKDPQNTQISGDSVGGSGVERWRNVAIRALKMTGQYSTA
                     NLNALLNQMRTESNGNPNAVNNWDINAKNGTPSKGLLQVIDPTFRQYAMPGFNSNIFD
                     PLSNILASIRYALSRYGSLTNAYRGVGYANGGIVNQHQIAEIAEGNKPEIIIPLDKAK
                     RSRAMQLLSIAMDKLGVSPKTYGNATTVSSDYEILEAIEKQAATTNQLLSLLLAFFKG
                     NSRTDRDLALDIQKILVRRM"
     gene            12741..13613
                     /locus_tag="LP245_002029"
     CDS             12741..13613
                     /locus_tag="LP245_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HBL1519930.1"
                     /translation="MRTVLLRNRINEEIDLSTEDYFATGLSNMGFEVKKEHVGQWGNF
                     RESSESVEISEFQSSVIISVHGFREKELYNSLVQFLSEGPFELEFAFDGETMVRRCSL
                     KSLSKTEIDPKTSLLTDTLELYFTSNWYSVKREKLIQRPNVVKTRGKVFPYKRSYIYT
                     QNLWEKKGVFKFNNNSVYLTNSKERMSPLKIRVIGKCSNPYWEVIQNSQIIATDGYFI
                     DMTETQTLEVSSLFEDTTAILKDIAGVESSVYQQQDYTKTNFVQAPTGEFSIVFHVGG
                     ADVEIELYEERDLF"
     gene            13610..14659
                     /locus_tag="LP245_002030"
     CDS             13610..14659
                     /locus_tag="LP245_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519931.1"
                     /translation="MILAVTLFHRDLMLYNEHLFSNSFEFGVDEINEEASSFTMDKYV
                     PVKTGDFLLAKYIPSGKFAYFGVITSQEDEKISCKSLLSLADSEIPTARVSGDNYEEH
                     IRRLIEYYLLNDPTKQLKDILDVKAESATSHSYQATDTNKHKLSAYILNGFKKYNVKW
                     YFKGIQNRKIYTGIRAVNESIYIKDNSSEFSDWDVFVQAPGAGNENKLLIVDKAMKDI
                     EKPIILSTWYLDEENNLTQDGSKENITKPTVNLVNIYDQTAEDKASYEDVAKSELKGN
                     TYSHEIKVNVVRNAKNLNVETIETGMFATISYKGKIYKSVLTAWRISSDKEFVELTFG
                     NIRSRFMDYFEDNGG"
     gene            14663..15487
                     /locus_tag="LP245_002031"
     CDS             14663..15487
                     /locus_tag="LP245_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519932.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVNSTGSTVSISKISDSYELTLS
                     KGEILWRGTALMHDTQTVQPSKKIWQTVSGFLLVWLPYENGQAIEDRYVTTPFYKERV
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            15505..17565
                     /locus_tag="LP245_002032"
     CDS             15505..17565
                     /locus_tag="LP245_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HBL1519933.1"
                     /translation="MANLEIKLSANKRQPYLRHRVVGRVGDGGLTTINVQLLEEDEIT
                     PFVINLNGTLKFVGEVSNGNYTEGEPEIIDSTNGLISYTFTKSNFSTSHQFKQAYFEY
                     VDPNGKKVTFQNFIIDVLERVDINSEQAKYYISSLEKLQSEMQTTFNQFISDKQVQYD
                     QIYSKYNELVRLINESDKQVNDRIDQTNQQIGDLGKLKKMYSNSIDFGGYDYSGNPNL
                     LSKLSYDLIENQNTSAGTLSKGENSFKYNKISAEVEGGVELYYKRRGIANWLPSNKTL
                     VMTVKLRAGADYSPVDGKLILIRYRYVDSGTGKIVLDLPINSNSITQEWKEFSITGTT
                     PTFSPQAYHPWIQFRAQDGVLGEIEMSYDIKIEEGSTATPYQPNLLDDSYWLGKTPLG
                     ENLITNAKFPIITRSNPISGFDISEELIIGETYTVSLKGTKPATKEFHLYYGEANYQQ
                     LQYQATLLPVEGLTDVWSATFTARNTSETTNLLRVALWQKPNSATYGTVQIDWLKIEK
                     GDTRTPNISQFKYFGEGLKDSNNPNDYSWDVTPEYTEKSLNNTVSLTEPQSIEGLKNF
                     EDGIQSKGKSVLTSDDNKYEVVTLTVTNGNTGSAKLYREGKTVTIYFFALNGKSSGGN
                     DSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSDYTFAI
                     TYTI"
     gene            17582..17731
                     /locus_tag="LP245_002033"
     CDS             17582..17731
                     /locus_tag="LP245_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519934.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            17728..18174
                     /locus_tag="LP245_002034"
     CDS             17728..18174
                     /locus_tag="LP245_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519935.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGVRSDGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYEALEHENGNLKQLNAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            18176..18313
                     /locus_tag="LP245_002035"
     CDS             18176..18313
                     /locus_tag="LP245_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBL1519936.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADRIISKEESA
                     S"
     gene            18348..18590
                     /locus_tag="LP245_002036"
     CDS             18348..18590
                     /locus_tag="LP245_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HBL1519937.1"
                     /translation="MKEEALQDVVERLVRIETKLDNYESLREKADSAKDLADKAYSVA
                     LNNAEDIKEMKANNKWSWGYMIGLGITIIGYFLTKL"
     gene            18606..18803
                     /locus_tag="LP245_002037"
     CDS             18606..18803
                     /locus_tag="LP245_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBL1519938.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            18814..>19652
                     /locus_tag="LP245_002038"
     CDS             18814..>19652
                     /locus_tag="LP245_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBL1519939.1"
                     /translation="MKKKIILSLSLIMALFLLPINGFAYTINNEFNLGVNEGSSQVAN
                     NQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSY
                     ANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLW
                     VTQNIWGDHTDPYGYLSEMGISKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAANP
                     TLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIYR
                     PDV"
BASE COUNT         6765 a         3400 c         4414 g         5073 t
ORIGIN      
        1 ataagtatcc agatataaaa acaatcggac acaagagaga tatgcaaatg aaagaagcta
       61 gacctagaga cgagatagac aaactataca agaccaaacg atggcgagac ctaaggcaag
      121 tagtaatagc tagggacttc ggcatgtgcc aagagtgcaa gcgtcgaggg cggaacacaa
      181 ggggcacgat catccatcac atagtcgagg cgagggaaga cctgtcactg ttctggtccg
      241 tagataacct tgaatgtatc tgtgtagctt gtcacaacag agagcatcca gagaggtcag
      301 gcgggaagaa gaaaccaaaa cctaaatcac atatcgttaa aatgtattca actcctgaaa
      361 gataagtttg cagtgaaatg aaggcagccc cccctactct aaaagattaa agagtaaggc
      421 ttgagaagaa cggtgctgtc cttccttcgt aaaaagaccg cttttcaagt tttttggaga
      481 aaaaggaaaa agccgaccaa tttaagccgg ctttggacga agctatttct tagtccattt
      541 gtttcctttt tgagaagtag ggggtaatcg gtcgcctgga tcaattttta cttcttgtcc
      601 gccttggaca tttccaccac gaggacccac ttctttgtag gttccttttg gtttgttgtc
      661 ttcgccgggt ttatagagtt ctcccatagg aatccctcct taacaaattt cggcacagca
      721 ctgccgataa cctaattata aggattgtga taacgatttc aatctatctt ttgaaagaag
      781 gtgatattat gccgcaacca gcgaagagtg caaaattaca attattaaac ggaaacccaa
      841 ataagaagaa taccgaagaa ctccgcaagc gagcggccgc agaagacaaa ttaaaaatgg
      901 ctactgacaa aatcaaaccg ccgttatggc tagattcgct aggaaaggat acctttgagt
      961 ttatcgccga tgaattgctg tctgtggatt taatcagtaa tccggacgtc catacaatgg
     1021 ctctatactc caattggtat tcgcaatacg tttctttaga aaaacagctt cgaaaactac
     1081 aacgagagta caagttgaac tatgcgcttg cgaaaaagga ggcagaggcg agaggtgagc
     1141 cgtttaatga acctaatgaa ttaattggta atccgctctc tcggcagatg gatacagcgt
     1201 ctcggaatct ccgttctttt ggcgctgatt taggactatc accagcagcc agagctaagt
     1261 tagctattaa gatggctgat gatggtggtg atgacgatga cgacttctaa tattttggat
     1321 atgtcttaca cagaacgtgt ggactattgg caaagctatc ttgaggagca agcttcttgg
     1381 ggtggctttt taaaatgtcc atatccggaa ttgttaacta cttggtatgc ggaacgatta
     1441 atcgatggaa gcataccagc cagcaaagaa aatattcaag ctgctaaacg gcatatgcgt
     1501 gatttgcagc gccaaggaac agatgatttt ccttggatct ttgacgaaga aaaaggtcac
     1561 cggcctatta gatatatcga aaaaaaatgt aaaccaactg aaggcgactt tggttcgttt
     1621 gttttgcaac cttggcagca tttcataatt ggatccatgt acggatgggt acatcgtgat
     1681 acaggagagc gtcgcttccg cgaggctctt atttttgttg gacgtaaaaa cgggaagaca
     1741 agtcttatct cgggcctttc cacatacatg gtcgcttatg atgatgaaca aggcgccaac
     1801 gtttacgtat tggcaaatgc tcgtgatcaa gcaagcttgt tgtttgataa ggccgcagaa
     1861 atggtcaaac aatcgccggc gctctttaag aaatttggta agcctaaacg atcaagtatt
     1921 aattatgctc ccgccttttc taaaatggaa ccacgcgcct cagatagccg gaaattggat
     1981 gggctaaaca ctcactttgg tatttttgac gagatccacg agtttacgaa ttacaatctg
     2041 atcaacgtta tcaagaaatc aagaggaacc agaaaacagc ctctgatagt ttatatcaca
     2101 actgctggat atgtattaga tggtccgttg atgtcttatt ttgagcaagg tgtggactgt
     2161 ttggaacatt tggaagatga catcgatgaa cggactttct attatctggc aaaacttgac
     2221 agtgcggaag aggctgatga cccaagatta tggatcaaag ccaatccgaa tatttgtcta
     2281 atgaattttg ttggcatgct agatgactat gttaaggata aaaaagatcc aaaagaatat
     2341 gctgactgga ttaccaagca atttaacttg ttttccgata tcgatgagct gtcatttgtc
     2401 gatatgccta ccattaaacg aaacaataaa accatcgata ttgaaacgct caaaggtaag
     2461 aagtgtgtcg gtggttttga cttgtccgaa acggaagact ttaccgcagc cgttttagaa
     2521 tttccgcttg aaacaggcga ggtattcatt ttgcaacaca catggatccc acaagctaga
     2581 tttgatcgag ataacaatca agagcgtatc aaagcgtggg agaaggtggg agatctaacg
     2641 attattcctg gtgattacgt caattatgaa tacgtcttaa attggtttgt agaaaattcg
     2701 aaaatctatg acattgtaaa aatcaattat gacaaggcca aggcgctacg attaaataaa
     2761 gaactagaaa atgcaggatt tgaaaccaac gagattcggc aagggtttct atcattaggt
     2821 gggccaatgc aaaacttcaa ggaaatgcta ttggacggta aggtgatttt caacaattcc
     2881 aagctttacc gatggtatct atccaacgtc aagctggtga tggatcgcaa ctcaaactgg
     2941 atgccgtcta agcagtccaa gagtagaaaa atagatggtt ttgcagcaag tttgaacagc
     3001 cacgccgaag tgttgaatat gttggttaat cctgtcggaa ccgggaaagt aacctattac
     3061 tcgatttccg atttaatgaa tatgtaagaa aggtgtggag gaatgagtat tttagatcgt
     3121 ttgcgttctt ttggccgagc gaagccgaaa gcgagcaaac aagagtattt tttgaatgac
     3181 ccgggattga taccgtattt agtcggaaaa gatgaaatat cagaagggat tttttccgta
     3241 attagccgtg tatcgaacgt ttttgcgtct ctccctctca aaatgataga tgtggagttt
     3301 ggccaaccgg acgactgtcc tgcatacaac ttgttgagcg aaggccctcg atattttaca
     3361 aagtttgatt ttttccggga cgtggaagtt ttgagaaact accaagggaa tgcgtatgtg
     3421 cagattttcc gaaatatcaa tggagaagta gcagatatgg cgttagtaaa acctggtgct
     3481 tgccatccag tgattgatat ggatagcggg gagctttact accaagtaac tgcgactgac
     3541 aaaggcagtt acaagcaagt tatctatgta cattacatgg aaatgcttca ctttaaacaa
     3601 ccgaggtttg gcggcttgga aggtacagac cccacaaaag tattaacgaa taccctcgga
     3661 tatgatcgag aagtccgaaa aatctcttta agtcagctta aaggaagtaa tgaagggcta
     3721 aaagttaagt ttgctagcaa tatggatgaa gaagctaaaa aagctacagt taaaaacatt
     3781 gctgattttt atcgacaaaa cggtggacta cttgtggaag aaaacggtgt agaaatcgaa
     3841 cgtttacaac gagagctggt agacagcaag cttttagata ctgataaagt atctcgctcc
     3901 agaatcgcta tggtctacaa tgtgccggag catttcatcg ggaataacca gtcgagttac
     3961 tcctctcagg aacagctcaa tatggaattt ttgacgtaca atctagtacc gaccgttaat
     4021 caatatgaag cggaactaaa taagaaaaca ctatcgagaa ccgaaaaagc aaaaggttat
     4081 cgatataagt ttaatgtcgc aagtttgcta agagctgaca ctcaggcaag gggacaattc
     4141 tatcaaatca tgcgacgagg cggagcatac tcagcgaatg atgtccgaag atttgaggac
     4201 ttgcaaccga taaataaaac cggtatggat gattaccata tttccggaga cctatatcca
     4261 atcgatatgg atccaacatt aagaaaaaca acctcgtcta aaagcgtagc cgaaaacggt
     4321 taggtttttt tagtttgcac cgaagggagg tggaaaaatg aaaaaagtga cgttaagcgg
     4381 cgatgtcgtg gataacgata ccgcgtggct ttatgactgg tttgggatca attgtatctc
     4441 accagggaaa atttctgccg ctcttacaga agcagcgggg gatgaagtag aacttgatat
     4501 ctcatcgaac ggtggggatg tcctagcggc aagcgaaata tataccgcta tccgtgccta
     4561 tccgggaaag gtatccggaa atgttgtgag tattgcagca agcgctgcaa gtgtaatcgc
     4621 ttgcgcttgc gaaccgctta gaatctcacc tacggcacac atcatgattc ataacgcatg
     4681 ggtgaccact agtggcaacg ctgaggaatt aaaagccaat gcagaaatgt taagcagtgt
     4741 ggatgagtct attgttaatg cttacgagat caaaacagga ctcgatcgga aaaaacttgc
     4801 tgatttaatg gcgaaagata cttggttaaa tgctcaaaca gcagtagcag aagggtttgc
     4861 agatgaaatt atgtttgcag aagcaccagt aacggtactc aatgcctctc aaccggttat
     4921 tccaaaaaac gcagtaacta agttgaaaaa tttaatactc aaagcggaag caccgcaaga
     4981 agaaacactc ttacagaaaa aactaaaagc cttaaatgga gggaaaaacg aatgaattta
     5041 gaacaattaa aaaatgcgtg ggtcgaggcg ggaagtaaag tctctgactt aaatgcacaa
     5101 ctcaatgcag cattggttga cgatgaaaaa acagaagaag atgtagtaag tttgcaagca
     5161 caagtaaaag cagcacgggc taaacgggac ggattgaaag agcaagtggc aaatatggaa
     5221 gccgaacaag tcttaaacgt caaaaaagaa ccattagata aaaaagatga aaacttgaaa
     5281 aacaagttta tcaaagactt taaagcgatg gtcaatggtg atcctgctat tatggctact
     5341 ttgacatcta atacggatga atctggtaat gctatcggat tgactattcc tgtagatgtg
     5401 caaacgacta ttcatacttt ggttcgtcgg tttgactctt tgcaagaata cgtaaacgtt
     5461 gaaaaagtga ccactaccag cggttctcgc gtttatgaaa aatggtctga tattacaccg
     5521 ttgactgctt tggatactga agacggtgaa atcccagcaa atgatgatcc tgcactttac
     5581 ttgatcaaat acttgatcaa acgctatgca ggtatttcca cagtaactaa cagcttgcta
     5641 aaagatactg ccgaaaacat tttggcatgg ttgtctaaat ggatcgcgaa aaaagtagtt
     5701 gttactcgca atacaaaaat cttggcagct attgatggaa tcaaagcggc acaaaagaaa
     5761 gatgttacag atgttgatgg aattaaagat atcgtaaacg tccaacttga tccagctatc
     5821 gaagctacat ctatgtttat tacaaaccaa gatggcttca atgttttaga taaagtgaaa
     5881 cgtgctgatg gatcttactt gttacaaaaa gacgtagctt ctgcaactgg atataccttc
     5941 ttaggtaaac caatcaagaa aattgcttct cgtttcttgc caaacaaagg tacgcaagct
     6001 actcctaaat atccactgta cattggtgat ctgaaagaag ccgttacatt gtatgatcgc
     6061 gaaaacatga gcttgctgac aacgaatatt ggtggtggag cttttgaaac agacaccact
     6121 aaagtacgcg tcatcgatcg cttcgatgtg caactagttg atgatgaagc ggttgttttg
     6181 gctactttta caactattgc gaacgagaca ccggcgaaag tttaaggagc tgattcctta
     6241 tgattcttga tcctaaaatg gatttaggcg aaatcaaaaa cgcactaaag attgataccg
     6301 atgatgacga tgtggaagta agccgtgcgg cacaagctgc aattgcatac attagagggg
     6361 ctatcgggaa tgataagccc tctttttata agcaagaaaa tgaaacggtt gatctgatta
     6421 atttagctat cctgcaatta gcagatcatt attacaacgc tcgatcagca accgtgagtg
     6481 ggaacttgcg agagtacgat ttaggtttta caagcctaat cttgcaactc aaagcaagtt
     6541 atttgctttt tgtggaggag gagtagcgta tgccccttat ccaaacagga aatttaaatc
     6601 aacgcatcaa gtttgtccga gatacgacgg ttaaggatga ggacgggcaa gttgtcccga
     6661 cttctacaac cattcttact tgctgggcaa gtgtgcagac acaacgcctg aacgatatta
     6721 agacgtcgat tggtacggct ttggaaggaa cactgacgtt cattatccgc taccaacaaa
     6781 aatcagagct gaccaatgat atgaaagtgc gttggaatgg aaaaacgttt gaaatcatta
     6841 cgattacgaa aggcgagttt gcgaaggact tcacgacaat cattgcaaaa gaggtttcaa
     6901 aatgagtgta gaagtcgatg caaccgaagt gtacaaagcg cttagggaag taaaagcaaa
     6961 cgttcaacga gtggaaagcc cagcacttag aaaagctggg gagtacgctc aagaagagtt
     7021 acgacaaaac acaccttact gggatggaac gaagtcaaac ggtaaacgtg gttcgtatat
     7081 gcaagaacat gctaagaacc atgtggttac aagctcgata aaaaacggat tggtagaagt
     7141 cggctatgac aaagatgttt cttggcggat gcactttatc gagttcggaa caatcaaaca
     7201 acgtccaaaa ggtttcgtac aaaaaacaca aaagcaaatc gaaaaacaag taacacaaat
     7261 cattgctgac gaagtaaaaa ggaggctagg actttgaaaa cggcagtatc acaagtctat
     7321 tcaattctga atagcaatga aaaaacaaag aacattgatt tttacaccaa tagtgttccg
     7381 gaatcagctc aaacagtacc tagccttcca gttggcagaa ttacagagat atccggcaac
     7441 tatgaagatt ttgcaagcaa caatcctttg accattcaat ttaacgtaca ggtagatgta
     7501 tgggtgtcaa ccatgaaaga ggttgatgcc ttttattttg cccttgatga ggttatgagg
     7561 gggaatggtt ggcaatgcgc atacacggaa caaacagatg acgaggactt ggaaggtgca
     7621 aagcggatta tcaaacgata tgtagcaaat atttcactaa attaaaagga gagaaaatag
     7681 atggcaacag taggattcga gagcgtcatt tttggcgtaa aaacaggtgc aggcggcact
     7741 ctaaaagaat tagtagcaga taagtcgaaa ggcggagcga tcgaagctaa aattactgga
     7801 ttaggcgcaa cttctaacac aacatacgct tcaaacgtac cgttcttcat tgcaagtaaa
     7861 ggggtttcgt cgccaaaagt tacgcttgac gtggcagact taatggataa cggcatttac
     7921 agcgaaatca ttggtgctaa aaccgtggat ggtgcaaatg taattggttc agaaactgaa
     7981 gcgccttacg tgtcggtagt catggttaca gcgaacaaag aaggaaaacg cttgttcatg
     8041 ggattgacaa aaggaaaatt cagtcatcca gatatcgaca tgaaaacagc tgaagacaaa
     8101 ggggtagaat tgcaacccga ttccatcgaa ggggaattca tttctgatga acgtggctat
     8161 gtatacttaa cagccgtaga atcagaagga atgaccttac aaaaattcaa ggacttggta
     8221 aataacaaag agggggagta gttaaccctg catctacacc aacgacagat acagggacac
     8281 caaaagaacc agaaccaaaa attgatacac aaggttagcc atttttggct agccttattt
     8341 tttgtaaaaa caaggaggaa aacaaatgat tgaattgcaa ttgaaacttg acggaaagaa
     8401 aaaaacattc aaacaacaag atatttccgc acgtgcaatg cgtgagtgta tcaaatttta
     8461 cgagaaagcg gaaaaagcag acctaactga tttagaagcg attgattcaa tgattgcaat
     8521 tacagcagat attttccaag atccagcagt tacatttgat gctattttag acggtttgac
     8581 tgcgagcgag ttagtaccgg cattagaaag tgtttttgaa caaataaatg aactgggaaa
     8641 caatgaaaaa aagcagacgg cgagcaaaaa gaaataagtt tttctgaagc taggaaagca
     8701 atggatcaaa tctacaaaga tttaatcgaa gcaggttgga cgatgagaga tgtggacgaa
     8761 gccgactatc attatttgtt acaccttttt ggagaagtgg agagtggcga agaatatgta
     8821 gatggtgctg atttcatcaa acaattttta tcggctgaag acttagtaaa acttgaggaa
     8881 ggaggtaaat aatggcagga aaaggacaac cggcaggaaa tatcaagcta gggattagtt
     8941 tagatagcac tagttttggt aacacgctgg acgaaatcaa tgcgaaagtc aaacaagctg
     9001 agtcgaatat gcgtgccaat ctaaaggctt atgattcagc aggacgttca tacgaagcac
     9061 ttagtcaaaa gacgaaagac ttgtctacgg ttatggaagg gcaaaacgcc aaagtaagag
     9121 aattaacaaa gcgccgtgat gaagcgatta gcaagtatgg cgaggaatcg aaacaagttg
     9181 ctaaccttaa cacacagata aacaatgcta ccgcaaaata taatgcttac agtcgccagt
     9241 tgaacgacac aaaaaaagaa ttggtgtatt ccaaaacagc cgtcaatgat ttatctaatg
     9301 aaatcaaaga aaatgaacga caaatgaacg ccgaagtaaa agcgttgaaa gccgctggtg
     9361 atgaatctgg tgcttttgaa gcaaaacaaa aagggctagc caaacaaacg gaattatccg
     9421 agaaagctat cgaagaacag cgcaaagttg tgaaactgat ggctgatgag tttggcgatt
     9481 cagcaaatga aaccgaagat gcaaaaaggg cattagaaaa gttagaacga caaagccaaa
     9541 tatctagcag gcaattagaa gcactcaaaa gctccagcga tcaatcagga aaagaaatag
     9601 aagattttgg cgacaagtcc acaaggtcag ctaggaaact ggacggacta aaagacaaat
     9661 taagctcgct aaaaagcgca ttttcgtttg gtgcagttgc tggattagcg cataacgcta
     9721 ttagcagtgt agtaagtggc gtgcaaggtt tggttggcga agcagtaaac gcatcggatt
     9781 cattgatgaa gttttccaaa accatggagt ttgctaactt tgggaagtca cagatagaaa
     9841 gctcgaaaaa agaaatgaaa gactacgccg ataagacggt ttatggttta gaagaaattc
     9901 tgaacacaac cgcacaattg gcatctaatg ggattcctaa ctatacagaa ctaaccaagg
     9961 cggcaggtaa cttgaatgcc gttgcaggcg gttctagtga tacattcaaa tccgttgcca
    10021 tgatgctaac gcagacggca ggagctggga aactaacaac tgaaaactgg aatcaattag
    10081 cagatgcgat accgggtgct tcaggattgt tacaagacgc tatgttgaaa aacggagctt
    10141 atacaggaaa cttccgtgat gcaatggcgc aaggtcaaat cacttccgac gagttcaacc
    10201 aagcaattgt acagttaggt atgaatgacg gagcagttaa ggcagccact tctacagaca
    10261 cattgagcgg ttcttgggag cagatgaaat ccactgtaat aaatgggcta caaagtatta
    10321 tagaaaaaat aggcgttgaa aatatcactg gtttcatcaa cagagtaaca aaagggattg
    10381 aaaattctat tcctaaaatt actcaattta taggttggtt gagagatatt ggaacgtgga
    10441 tcgttgaaaa tagagagcca ctaacatgga ttgtcggaat cataggcgga attacattag
    10501 cagtaaaagc attgaacgta gcaagtatgt tgctggcaat tactggcgga acattggcag
    10561 ccccttttgt ggcgattggt gtagcattag gcgcactagc aggtgctttg gtgatagctt
    10621 atacaaaatc tgaaacattt agaaatatag tcaatgcggc ttttacagct gtgaaaaacg
    10681 tagttatgag cgttatcaat aatttggtgg aatactacaa aatgttgtgg agcgtgttgc
    10741 agtggctttg ggaaaaaata aaagaatggg cttcatggat tggcaataaa ttcattgaaa
    10801 tgaagaacag cgttgtgaat acggttcaga acctatggaa tggcgtgaaa aacttcttca
    10861 gcaatggcgt tggagatacg tggaataagg tagtcggttg ggtaaaaaac attttcaaca
    10921 aagcaactga attgaagaac aacgtttctg atgtaatcgg taacctgtgg aatggtatca
    10981 aagacacatt ccgtagaggt atcgatacgg tattcaattg gttttcagaa ctaccaacga
    11041 agatgaagaa tgccattatt ggcggtaaaa acgccattgt tgatgcgttc aaaagtattt
    11101 tcaacgcagc acttaaagcg ataggtaaac cagttaacgc aatcatccat ggagcttcat
    11161 gggtactaga aaaattgggc gcagaacctc tacaagaatg ggatgtacca caatacgcta
    11221 caggtacacc agcaggtggg cacccaatca atggtccaat gatggttaat gatggacgtg
    11281 gagcagaaac agttatcaca ccagatggta gagccttcat tcctaaagga cgcaatgttg
    11341 ttctaaacgc accaaaagga acgcatgtct tgacagcaga agagaccgcg caacttcaag
    11401 gttctaaagc tcctaagtat cgttacaaaa aaggtactaa cttctttggt aacatgtggg
    11461 atagtgtgaa aaaggttgct ggtaatgtag gtcacacaat taaaaacgta gtaggtgacg
    11521 tgtgggactt tatttcagac ccgggagcgt tagctagaaa agtacttggg gggttagatg
    11581 tattaggtgg attgacaaag tatccattag aagtaggtaa aggcatccta tctaaagcaa
    11641 caagtgcact gactgaaaaa atcactgggt tgttctcatc tggtaactta gatacctccg
    11701 taggaacaaa tggcgtctat aaatatttgg ctgatgttgc taagtctgtg atgaagaaat
    11761 tcccaggatt tgtggcaact agtgggtata gaccaggtga cccttattca catggtaaac
    11821 gtaatgccat tgatattgca ttaccaggcg tcacaggagg ctcacctaga tacacagaag
    11881 cagcaaacta cgcttttgac aaattcgctt ccaaaattgg ttacgtaatc actaatggga
    11941 aagttcgtga ccgttcagga caatcaggtc aaccagcaac tggtgcatgg gagccatggc
    12001 ccgatggaga tcactatgat catgtgcatt taaacggtgt gaaagaccca caaaacactc
    12061 aaatttcagg agatagcgtg ggaggcagtg gggtagaaag atggcgcaat gtagcaatta
    12121 gagcgttgaa aatgaccggt caatacagta ctgcaaactt aaatgcatta ctaaatcaaa
    12181 tgcgtacaga gtcaaatggt aatcctaatg cagttaacaa ttgggatatt aacgccaaaa
    12241 atggaacacc atcaaaaggg ttgctccaag tgattgaccc aacattcaga cagtatgcaa
    12301 tgccaggatt caacagcaat atttttgacc cactatctaa catcttagct tcaatcagat
    12361 acgcactatc aagatatggc tcactaacaa atgcctatcg tggagttggt tacgcaaacg
    12421 gtggaattgt aaaccaacat caaattgcgg aaatcgcaga aggaaacaag ccagaaatta
    12481 ttattccgtt agataaggct aaacgatcaa gagcgatgca attattgtct atcgcaatgg
    12541 acaaactagg agtttctcct aaaacttatg gaaatgcgac aactgtttcc agtgattacg
    12601 aaatcctaga agccattgaa aaacaggcgg caacaacgaa tcagctgtta tcgttattgc
    12661 tggcattttt caaaggaaat agccgaactg atagagattt agctttagat attcagaaga
    12721 tcttggttag gaggatgtag atgcgaactg tattactgag aaatagaata aacgaagaaa
    12781 ttgatttgtc cacagaagac tattttgcta ctgggttgag taatatgggg tttgaagtaa
    12841 aaaaagaaca tgtgggacag tgggggaatt tcagagaaag cagtgagagc gttgaaatat
    12901 ctgaatttca gtcatctgta atcatttctg tgcatgggtt tcgagaaaaa gaactgtaca
    12961 attcacttgt gcagttccta tcggaaggtc cgtttgaact ggaatttgct tttgacggcg
    13021 aaacaatggt aagaagatgc agtctaaaat ctttaagtaa gactgaaatc gatccgaaaa
    13081 catcgttact aacagacact ttagaactat atttcacatc aaactggtat tccgtaaaac
    13141 gcgaaaaatt aattcagcga ccgaatgtag tgaaaacacg tggtaaggtt tttccgtata
    13201 aaagatctta tatctacact caaaacttgt gggagaaaaa aggtgtattc aaattcaata
    13261 ataattctgt atacctaacg aatagcaagg aacggatgtc cccgctaaaa attcgtgtga
    13321 ttgggaagtg ttcaaatccg tattgggaag taatccaaaa ctcacaaatc atcgcaacgg
    13381 atggatactt catagatatg actgaaacac agactctaga agtatcaagc ctttttgaag
    13441 atacaacggc gattttaaaa gatattgcag gggtagaatc ttctgtctac caacaacagg
    13501 attatacaaa aactaatttt gttcaggccc caactggaga attcagcatt gtgtttcatg
    13561 ttgggggggc agacgtagag attgagttat acgaggagcg tgatctgttt tgattttagc
    13621 agtcacgctt tttcatcgtg atttaatgct ttataacgaa catttattct ctaacagttt
    13681 tgaatttggt gtggacgaga tcaacgaaga ggctagtagc tttacgatgg ataagtacgt
    13741 tcctgtaaaa acaggcgatt ttctactagc aaaatatatt cctagtggaa aatttgcata
    13801 ttttggtgta attacgtcgc aggaagacga aaaaatcagt tgtaaaagct tacttagttt
    13861 agctgatagt gagataccga ctgcacgtgt gtcaggagat aactacgaag agcatatccg
    13921 gcggttgatt gaatactatt tgctgaatga tccaacgaaa caactaaaag atattttaga
    13981 cgtcaaagca gaaagtgcga cctctcattc gtatcaagct accgatacga ataaacacaa
    14041 gttaagtgcg tatattctca atggtttcaa aaaatacaac gtaaaatggt atttcaaggg
    14101 aattcaaaac agaaaaattt atacaggcat acgtgctgta aatgaatcaa tttacattaa
    14161 agacaattct tctgaattta gcgattggga tgtgtttgtt caggcgccgg gcgctggaaa
    14221 cgagaacaag ctattaatcg ttgataaagc aatgaaagat atagagaaac cgataatact
    14281 gtcaacatgg tatttggacg aagaaaacaa tttgacacaa gatggatcga aagaaaatat
    14341 cacgaaacca actgtcaatt tggttaatat ctacgatcaa accgcagaag ataaagcatc
    14401 ctacgaagat gtggcaaaat cagagttgaa aggcaatacg tattcgcatg aaatcaaagt
    14461 gaacgttgta agaaatgcaa aaaatttgaa tgtcgaaacg attgaaacag ggatgtttgc
    14521 cacgatttct tataaaggaa agatatacaa gtcggttttg acagcttggc gaatatcaag
    14581 tgataaggag tttgtggaat tgactttcgg aaacataaga agtcgtttta tggattattt
    14641 tgaagataat gggggataaa aaatggttag caatgtggat ggatatcaat ttgaaaacgt
    14701 gaaagtaagc gcagaaaatg atgctagact ttatcacgtt ttatataatc ggaaaaatca
    14761 ggttattgat ggttacgatc agtctatgaa tttatcttca agcggattaa cagtaaaagt
    14821 tgctgcagga gcagcgatta ttcaaggtcg tatggtcgtt gttcgacaag aagaaagtat
    14881 aacagttcca gcaaactcaa gtggttatat agcattaaca gtggatttga cacaagaagt
    14941 tatacctgga tctattcttc cagaatcgga agaatatgaa tggactaata atcaagtcaa
    15001 gctagaattt ataacaaaag ttataaaagg taatttaaac aatggtgata aggtctataa
    15061 tttaccacta tgctcagtta attctactgg atcaactgtt tcaatctcaa agatatcgga
    15121 tagttacgag ctgactctct ctaaaggaga aattttgtgg agggggactg cgttaatgca
    15181 tgatactcaa actgtccaac cttcaaaaaa aatttggcag acagtttcag gttttttgtt
    15241 agtatggctc ccatacgaaa acgggcaagc aattgaggat agatatgtaa ctacgccttt
    15301 ttataaggag cgtgtaactt ttactaatgt tttaggagaa attgtttcag gatttgatga
    15361 ctatcacaaa aagtggttta gtaaacgaat aaactataat tcgaatacta atatatttac
    15421 aggtgcagca agcaatgcaa gtggagataa cgcaaatatg gtgcttaggt atatagtttc
    15481 tttttagtta ggaggtatgg aagagtggca aatttagaaa ttaaattatc tgcaaataag
    15541 agacagcctt atctacgtca ccgtgttgtt ggtagagttg gtgatggggg gctcacaaca
    15601 atcaatgtac aacttcttga ggaagatgaa attacacctt ttgtaattaa tctaaacggt
    15661 actttgaaat ttgtgggcga agtttcaaac ggtaactata ccgagggaga accagaaata
    15721 atcgattcga ctaatgggtt aattagttac acgttcacta agtcaaattt cagcacgagt
    15781 catcaattca aacaagcata ttttgaatat gtagatccta acggcaaaaa agtaactttt
    15841 cagaacttca tcatagacgt gttagaacga gtggatatta attcggagca agcgaaatac
    15901 tatatttctt cattggaaaa attacagagt gaaatgcaaa ccactttcaa tcagttcatt
    15961 agtgataaac aggtccaata cgatcaaatc tactcgaaat ataacgaatt agtaagattg
    16021 ataaatgaat cagataagca agtaaatgat cgtattgatc aaaccaatca gcaaatcggc
    16081 gatctcggca agctgaaaaa gatgtacagt aacagcatcg actttggggg ctatgattat
    16141 tcggggaatc cgaatttgtt aagtaagcta tcatacgact taattgaaaa tcaaaatact
    16201 tcagctggaa cactttctaa gggtgaaaac tcgtttaaat ataataagat atcagctgaa
    16261 gtggaaggtg gagtagagtt atattataaa cgaagaggta tagctaactg gttaccctct
    16321 aataaaacgc ttgtaatgac tgttaagctt agagctggag cggactatag tccagttgac
    16381 ggaaaactta tactgattag atataggtat gttgacagtg gaactggcaa gattgtttta
    16441 gacttaccta ttaacagtaa ttcgataact caggaatgga aagagtttag tattactgga
    16501 actactccaa catttagccc acaagcatac catccttgga tacaatttag ggctcaagat
    16561 ggggtacttg gggaaataga aatgagctat gacatcaaaa tcgaagaagg ctctacagct
    16621 acaccatatc agcctaactt acttgatgac tcttactggc taggtaaaac accgttgggt
    16681 gagaatttga taacgaatgc caagttccca attataacac gaagcaatcc tatttctggt
    16741 tttgatattt cagaagaatt aataataggt gaaacttata cggtatcttt aaaagggact
    16801 aagccagcta ctaaagaatt ccacttatac tacggagaag caaattacca gcagttgcag
    16861 tatcaggcaa ctttacttcc tgtggaagga ttaacagatg tgtggagtgc cacttttaca
    16921 gccagaaata ctagtgaaac gacaaattta cttagagtag cgttatggca aaaacctaat
    16981 tctgcaacat atggtactgt tcaaattgac tggctcaaga ttgaaaaagg cgacacacgc
    17041 acaccaaata tcagtcagtt taaatacttt ggtgaaggct tgaaagacag taacaatccg
    17101 aacgactaca gctgggatgt cacaccagag tatactgaaa aaagcttgaa taatacggtt
    17161 agtctgactg aaccgcaatc catcgaagga ttgaaaaatt tcgaagatgg tattcaatca
    17221 aaaggaaaat ctgtattgac atcagacgac aacaaatatg aagtcgtaac cttaacagtt
    17281 acaaacggga ataccggatc agcaaagctt tatcgtgaag gaaaaaccgt cactatttat
    17341 ttttttgcgt tgaatgggaa aagcagtggt ggaaatgatt caacgatact aacaattcca
    17401 gaaggctatc ggccaccaat tagttttgag caactggttg gctcgataga ccgttctact
    17461 ttgaacagtg ctcagttatc tattggtgca gatggagcca ttaaatggcg aagaaactca
    17521 agttatggat cggattatac ctttgcaatt acttacacga tttagaaagg cgtgaatcga
    17581 tatgaaggca gcatatagac caattgaacc ttacggattc gagcaaatca ttgtgaatga
    17641 tgaagaacat ttaccggaag aatgcacaga agtcgaacca ccgattccaa attggaaacc
    17701 gaaattcaat tactgggagg gaaataaatg aaaaacattt ggaaatatgg ccgtactggc
    17761 ggagagtatg caggaaaagt attggacgac atgcttgtat ccgttcctta cacagatcag
    17821 ccaccgctcg aaggggttcg ttcagatggc gaaccgctaa cgattgctga tcagatgttt
    17881 gatcctaaat tgaaccaatg gattatttta gcgaacgcgt tagatcacaa cgatttaaac
    17941 aatctcaaag cgatgtacga ggctcttgaa catgaaaacg gcaacctaaa acagctaaat
    18001 gccaaactca tgctaagcga tgtagcgatt aaacaggaaa atactgcatt gaaagaaaaa
    18061 gctgacagtt tagcacaaat caattcaaaa atgatgcttg cttcgttaca aaatagcaaa
    18121 gacatttcag aaattaaaga gcaactaaat ccagcttcaa agggaggtga gtagtatgtt
    18181 tagttttagc gatgtgaaaa tgatgtatga ttggggctgt tttactgacg atcaagttcg
    18241 tctattcgtt ccactatgta tcacagatga agaagcagat agaattatta gcaaagaaga
    18301 gagcgcatct taagtgatgc gtttttttgt tggaaagttg gtggaacatg aaagaagaag
    18361 cgctccaaga cgttgtggag agattagtaa gaattgaaac aaaattagac aactacgaat
    18421 cacttagaga aaaagctgat agtgcaaaag atttggcaga caaagcctac tcagtagcgc
    18481 taaacaacgc agaagatatc aaagaaatga aagccaataa taaatggtcg tggggttaca
    18541 tgatcggttt aggcattacg atcattggct atttcttgac taaattgtaa aggagttaag
    18601 aagaaatgat tttacccgat aagtattatc aagtcattaa atggacggtt ttaacagtat
    18661 taccagctgc atctgtttta gtagccacgt taggaaaagc gtatggatgg aatggaacag
    18721 atatgacagt actcactatc aatgcagtag caacattttt aggcgttatc actggtgtgt
    18781 ctgcatataa cttaaaaaaa taggaggaaa aaaatgaaga agaaaatcat tttatcattg
    18841 agcctaataa tggctctttt tttattgcca attaacgggt tcgcctatac gatcaacaat
    18901 gaatttaatt taggtgtaaa tgaaggtagc tcacaagtag caaataatca gtatatttta
    18961 ctgcatgaaa cggctaatga aacagcgaca ggacgcaatg aagcacagta tatgcaacgt
    19021 tcatggacta gtgcttatac tgcttacatt gtgggagacg gcggaattgt ttatcaagtc
    19081 ggtcaacctg gttatgtaca gtacggtgct ggttcgtatg ctaatgcaaa tagtcctgtg
    19141 cagattgagt tacaacacac acatgataaa gcaacttttg aaaagaacta taaagcatac
    19201 gttgaattgg ctagagattc agcaatgaaa tatggtattc cattaacatt agacactcct
    19261 tataaccaac caggaatcaa atcgcattta tgggtaacgc aaaatatttg gggcgatcat
    19321 acagatcctt acggttatct ttctgaaatg ggcataagta aagaaaaatt agcatatgat
    19381 ttagctcatg gatttaccga tgaaaatcca actacttcag atgataaacc agtcattgat
    19441 ccaactagag caggtgctgc aaatcctacg ctgacagatg gaacaaatta cgcccacatt
    19501 gatcagttcg gagaaatcga aaacgcaaac ttgcatgtag caggatggca tattgctaac
    19561 tataaatacg agtatatttt cattatggat tacaatactg gaaaagaatt agctcgagta
    19621 aaagctgatg ggatttatag accagacgta aa
//
LOCUS       DAFEEZ010000053        19462 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000053
VERSION     DAFEEZ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.055"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(1..153)
                     /locus_tag="LP245_002039"
                     /pseudo
     CDS             complement(1..153)
                     /locus_tag="LP245_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1122..2372
                     /locus_tag="LP245_002040"
     CDS             1122..2372
                     /locus_tag="LP245_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HBL1519940.1"
                     /translation="MKKQYNIAVAGTGYVGLSIATLLAQHHKVTAVDIIPEKVELINN
                     RKSPIQDDYIEKYLAEKELNLTATLDAKAAYQSADFVVIAAPTNYNSRTQHFDTSAVE
                     AVIRLVMEVNPDAIMVIKSTIPVGYTASVRVKTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMDDERLVEDAHTFATLLQEGAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPENLIEAIVESNRTRKDFIADRVLQMAGYYNYAEANQYDAGKEKPVVIGVYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPTLKDGETFFGSKVVNDLEQFKAMCDSVI
                     ANRYDACLDDIKEKVYTRDIFQRD"
     gene            2391..3401
                     /locus_tag="LP245_002041"
     CDS             2391..3401
                     /locus_tag="LP245_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBL1519941.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFKENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSAELSYSRTERVTSIEDIEHPAIRNAMKMLDVHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALEGKYADKKKLADEAIYLERVLCNEAGGWQDQIAASYGGFNRI
                     NFNVDGYEVLPVIISPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAILTDKNRNLDDFGRQLDVTWRLKKGTGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQDAVRWAMRDLMYIPFEFEDGGTRVIHYTPETYIEKQ
                     NG"
     gene            3411..4064
                     /locus_tag="LP245_002042"
     CDS             3411..4064
                     /locus_tag="LP245_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1519942.1"
                     /translation="MLAEKLNKHIDLLIKRYPTLETIKQDIIDGYLIMEECYLNGGKL
                     LVAGNGGSAADSEHIAGELMKRFKTPRPVSKEFADKLVAIDPVRGPELAKNLECGLTA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRSGDVFLGISTSGNSKNIMSATVVARA
                     LGIKVIGLTGAKGGELATVADVCVKAPEVETYMIQEYHLPIYHCWCLMLEDKFFGNE"
     gene            4083..5081
                     /locus_tag="LP245_002043"
     CDS             4083..5081
                     /locus_tag="LP245_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBL1519943.1"
                     /translation="MKKTIMVTGGCGMIGSNLVKRLVKEGCWDVYVADNLWRGKLEYL
                     NDEDGHPVIDLDTHFFNADLTDYEQAKKVIGTTEYVVHLADVVAGIDYVFKNQGELFR
                     INNLINSNVFDCCRKAGKEKIKGVIYVGTVCSFPLTRQNTLNPEPLREEELFPALPES
                     AYGWSKLMGQLEMGYLEKETGIPCCILMLHNVYGTPTDFGERSQVIPALIRKAINNPE
                     EPFNVWGSGEQGRAFIHVNDIVNALVLALDKGWGHGHIQIGPSHCTSIKEIAYKIIEI
                     SGKDIKPFFDTSKPEGDKARCADYSKAKEILDWKPTVSLEEGLRESYNWIEKQIKG"
     gene            5157..5918
                     /locus_tag="LP245_002044"
     CDS             5157..5918
                     /locus_tag="LP245_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HBL1519944.1"
                     /translation="MEKNMYKRKRDFTVCGIVGVCATTKNEFVREVFSMPTSPVSATV
                     DLVGVPAIISAKENPKIAEMYSQATMAAIDGMPIVKIGRRKGFTCERCAAPDIMGMVF
                     EEGVRQGKTHYFYGGKDNEVLNKLRANLERDYPGIKIVGMYSPPFRPLNEEEDSKICE
                     EINNLNPDFLWVGIGAPKQEMWMWEHQKKIHNTVMFGVGAGFNFFAGTLEKAPEWMEK
                     ASLEWLFRLVKEPRRLWRRYILGGIKYIYYTIESK"
     gene            5936..7042
                     /locus_tag="LP245_002045"
     CDS             5936..7042
                     /locus_tag="LP245_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL1519945.1"
                     /translation="MKILIVVTMTNNFGKKGSYNSQEIGLARGLAELGHEVIVYKSVK
                     SDEEVGTEQLSNTAMIHYIKCRYVGSNGFLSTKNFDKNADVLIQFADLQLSVPHVYSW
                     TVKNGIKYIPYNGITRSQSGNKYIKTIIEILAHRNYKIYKKNGCVAKNDRVSEKLVQL
                     GVNKVKLAPVCVDFEQLHKNYEAIDFTTLREKWNIPRDVRVILYVGRFEKDKRPLDMI
                     SLFNKLDEHNYLLMVGTGALLEQTKQQINLLGLQNRVKIIERIPNKDIWELYCLSDVF
                     VNLNYTEIWGMVLLEAMYYRLGIIAVNAPGPQNIILDNRYGMLAKSDDEILTFLKDGR
                     FTNDIIDAAYQRVTTEFRWSKSGEIMLSMLEGDK"
     gene            7032..7265
                     /locus_tag="LP245_002046"
     CDS             7032..7265
                     /locus_tag="LP245_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519946.1"
                     /translation="MINDMEVTKLMALRNRYALNIVDNCTRKIAKILGCCIGKGAQIG
                     NSVEFVHNSVGTVIHSDTILEDGVKVYQNVTCG"
     gene            7464..7919
                     /locus_tag="LP245_002047"
     CDS             7464..7919
                     /locus_tag="LP245_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine acetyltransferase"
                     /protein_id="HBL1519947.1"
                     /translation="MNAYKLYKVERWFYLHKMEFFAKIVKALIYVLHNSSISYQTEIG
                     DNCKFLYGGIGCVIGKDTKIGNHVIIGTNVLTGGRSNKPGMPTIGNNVYIATGAKILG
                     NITIGDNVIVGANAVVINDVEPNCSVGGVPARVLKKDIDVNDYCSLNRY"
     gene            7933..8706
                     /locus_tag="LP245_002048"
     CDS             7933..8706
                     /locus_tag="LP245_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1519948.1"
                     /translation="MLYFVIPLMSAKAANNWEMVSTLFNRTLWSCYNQTDPDFKIIVA
                     CHEIPKLTHEYDDRVEFIQVSEKDAPIPTNQDEKMIDKGYKTHALAMRLRELGGGFAM
                     MVDADDLVSSHLAEYVNSHPQENGFYVKTGYVYFVGDDYMKVLPKFSSGSACIVKYAV
                     EDLPEAYPEVMTANCDDNPWIIRKRHGGVVPACEEQGRPLKPLPFKAAVYVLGTGDNH
                     SLYGKTTKYQTKMREILEMFIAKRKIKGKLKAEFSVDWL"
     gene            8693..9823
                     /locus_tag="LP245_002049"
     CDS             8693..9823
                     /locus_tag="LP245_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL1519949.1"
                     /translation="MIGYKVSIMKVLMCESQMPENWYSFDLSKELNQYVDLTLLCKRD
                     VPPLDPKIKSKHILYHKSTNKVFSALVFLKSLFLIWKEIRFGDYDIVHLQLMKSLKYE
                     GGLYVLCKRHYKKLIMTVHNVLPHEVREKDRQEHFNIYSNCDGFIVHNRVTEQHLYAE
                     FPELNAKSYVCPHAIYGDVKHISRAYDKDKFEFILFGQIRPYKGIDVLLNAITELPMD
                     VRKKVHFTIAGQQHPKQDSTDYKKMIEDLKVSDCVLYKPERISDEEMDSMFRNADAAI
                     FPYKEIYGSGALLMAYTYCLPTIVSNVPAFMEETEEGKIGLLFENLNSKSLADTIVKY
                     VNLSPAEKSKIEDDIYELVNRKYTWAASAKLTYEAYKQILNE"
     gene            9854..11089
                     /locus_tag="LP245_002050"
     CDS             9854..11089
                     /locus_tag="LP245_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519950.1"
                     /translation="MQISKWKIIQFLMVFLMIISSSILKPLGGWLGETMNVRLVTVIL
                     AIVCLLIASLPAFRKNRYLNFCTLLICVVIIAAYIYSDKTIWVKSRESMSLYYVLLAY
                     PLFCTLINQAWNLDSMLNTICGVTFLSYILRTSISLIQKFSGVLLYENIYRECAPENW
                     YRGGFLRINPPCFTIIIIPIALYMIERQVVARRKVKYYLLIASALAYSAVIHGSRSVL
                     VYQIIVLGCYILFKKGSSKRKIAMWVLAGLLVVIFINSTMFSTFVETFTNSTGEYAGS
                     AESRFASVWFFVPKFLQSPLFGTGILTGEEFTFILPGGVRGHLSDIGFFYTITQYGVG
                     ILIFDILFIIKGFKTALLASKVGMTGYQYLAFGITLSVLLTGINIDWFYPIFTPAIPV
                     CLAVIEYIYQECRSVANIE"
     gene            11114..12223
                     /locus_tag="LP245_002051"
     CDS             11114..12223
                     /locus_tag="LP245_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519951.1"
                     /translation="MNKKEILYNILKKYENLPYVFRNMFGHNISKLVSWKLTADCATV
                     EENSEVYAAFQLRSKDMSDVPVMGLVNCCKDVAIVMQGPLCLKDDFSYNTLAYYKKCY
                     PNALIILSTWKDEDIKALKRIEDLGVIVICSEKPEKPGHLNINYQVGNTLPGIVRAKQ
                     LGAKYVCKTRTDQRIYHPNAMAFFCSLLEQYPVNNEDDWKLIQNQRLLLLSMPYGDMF
                     FPYCLSDFLYFGDVDDMINLFSIPSDVREKGAVSRGVSRREISENNLAPEVQLLRSYI
                     SRMGGNEECSIRAYWEFVKNHVITINKNQIDLYWHKYVGRYSNNTIYGTYYIDDSQDA
                     LHCYNFDFINWLNLYTGKYEYKAKYEKYMDFVWEE"
     gene            12265..13599
                     /gene="gmhB"
                     /locus_tag="LP245_002052"
     CDS             12265..13599
                     /gene="gmhB"
                     /locus_tag="LP245_002052"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HBL1519952.1"
                     /translation="MKTVIMAGGRGSRISELFPDIPKPMIPIDGIPVLERELCSLRDQ
                     GFNDIILTVSYLHEKIEEHFGDGSKLGIKIKYFIEKTPLGNAGALYFLLDELGDEPFL
                     LLNADAVFDVDFRQMIRFHVENNADVTLFTHPNSHPYDSGLIISDDNKKVLQWLAKED
                     QRPEYYKNRVNAGLHVINPKVLRENPLMEIVNKSIVEGGGLPYKIDLDRMILKPLANT
                     GRMYCYDSPEYVKDMGTPDRYRAVIKDFQKGIIVGKNLSNPQKAIFLDRDGTINKYVG
                     FLRNAEEFELIDGVSEAIKIINSLGFLCIVITNQPVIARGEVTVDELNSIHNKLETML
                     GHAGGFLNGIYYCPHHPHKGYAGEVIELKIDCNCRKPKPGLLLEASKDFNINLSQSFM
                     VGDSESDVIAGKNAGCKTVLITEDITLPANYGQDYSVCSLLEFVKNHLCTMQ"
     gene            13634..15271
                     /locus_tag="LP245_002053"
     CDS             13634..15271
                     /locus_tag="LP245_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HBL1519953.1"
                     /translation="MKVLIPAAKVVEKELQSIGMLPAIIYPINKKIVFDYLYNQYNAI
                     CDSLDIICYEKADKVHRRLKNYHDSRIHICDLPELGDLGQTVYFGLSDEDEPVLINFA
                     DTIVMESMSDIEMDTFYYSEDFVSSTWTYFKINEGIITDIHDKEEAYVSDKREKLFIG
                     VFMFSSSKLLKSCLREAVESRKQGGINSFYRALQLYSERCPLKAVRTEKWFDIGHIDK
                     YYNTKLEVKAREFNHISIDKDRGILKKTSDDKDKFIGEIKWYLKLPADIEYVRPRIFD
                     YSTSYVAPYVDMEYYAYHTVHELYLYGDLKYNQWHDLFSRIKFICSDFKRYTLKDEKI
                     RESLEDMYLRKTMQRFQKLSEDKRFSAFFEKQIQINGRKFISLTGVIELLKNLIPSML
                     YDVNEFCIIHGDLCFANMMVDSNCSFVKVIDPRGKFGKYDIYGDSRYELAKLFHSLDG
                     KYDYIIKDLFTVEYDTECAVIDYTINTRVRDYDLFELFKSVFSDEIKDDFDKIVLIEA
                     LLFLSMIPLHGESFDHQIVMLATGMELLARVSNKVIL"
     gene            15373..15768
                     /locus_tag="LP245_002054"
     CDS             15373..15768
                     /locus_tag="LP245_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HBL1519954.1"
                     /translation="MYSEYSFVFDIDGTLCPIKKKDERYEDLVPYENMVEKLRFYKEN
                     GAKITLFTSRNVNSYKGNLGMINANTAKVLLAWLDKWDIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLRCSVDELNEICNSSKKRF"
     gene            15786..16517
                     /locus_tag="LP245_002055"
     CDS             15786..16517
                     /locus_tag="LP245_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1519955.1"
                     /translation="MEKKMTVIITMAGLGSRFRKIGYAVPKYMINAKGRTLFDWAMDS
                     LVGYNKNVDKYIFVVRQEDNASAFIKEHCAYFGIENVEVIEIDYMTDGQATTCMLAIP
                     YCNQDNEIMVYNIDTYVESNEMKYEDICGDGHIPCFHADGDHWSFAKLNDRNEVIEVR
                     EKVRISDNCTLGAYYFSSAKLYKALYEEYYADSSNMEKNEKYIAPLYNFMIKKGLKVT
                     ISIVDAKKVHVLGTPEELNVFLNQE"
     gene            16541..17992
                     /locus_tag="LP245_002056"
     CDS             16541..17992
                     /locus_tag="LP245_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBL1519956.1"
                     /translation="MTSNNLIVKTLSRYKNTPLPVKAALWFMVCGFLQRGVSMITTPI
                     FTRVLSTEQYGLYSTYLSWESLLLMITSLSLFKAMMNLYVKYDNQEHILSTVSGLTLV
                     LTIFWFVIAIFIKDILAEILGLTPVLVVCMFSYFIFQAEIQCWSLHKRYIYDYKTLLV
                     ATLAVTVGSSVVGCLAVLFISPTAEARALMNVLVTGVVGVAVYISVFRRCKDFKDNEV
                     WNFAVVFCVSLMPHYLSEFILNGSDKIMINYLCGSSDVAIYSVAYSIGALINLVTNSV
                     NSTFAPYQYQKIKSGEYDLLSKRANEVLGLVAAMLFALMLFSKEIVLIFGGQKYIDSV
                     NLIVPICIGIYFNYMFQLFARVQEYFEKKLTVVIPSVLCAIMNIVLNYVFIKLYGYQA
                     VAYTTVFSYMFFCVIHYIFYRKVCKELLDGKNIYDVRGILLISAITIAGGILISIINK
                     FDFIKYLIIAIACVAAIIFRKRLLLLVRRIMSK"
     gene            18018..18629
                     /locus_tag="LP245_002057"
     CDS             18018..18629
                     /locus_tag="LP245_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL1519957.1"
                     /translation="MIDIISAIMVNVLTALYQPFLFAVLTAYLFMYWYLFIVDNSRDP
                     KNLKDSVLIWLRYFKASSKFRRLFFLAFYFTLILFKTLLNRNMWMNPLSNVIGQWSLY
                     IIDNATGESRLTTECVENTMLFIPFCMLLLWWRDIKCDIIRTIYVGIKYVFLFSLSIE
                     FTQLFFRLGTFQLSDLFYNTLGGLIGALLYWLFYRLNKYIDLK"
     gene            18811..19326
                     /locus_tag="LP245_002058"
     CDS             18811..19326
                     /locus_tag="LP245_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HBL1519958.1"
                     /translation="MVVVMVKVFDIIKFSDFRGYTAVALDNETLFSIGIEFHIKQINQ
                     GFSHNKYTMRGLHYQSGEHAQGKIVMCLHGEIMNIALDIRQGSSTYGCVYVNTLSESN
                     GKCAYIPRGYAHGYLTMEDNTLVQWCVDNDFNSNAAKCISYESVDIEWPVSRQCFVIS
                     EKDKNGERLSF"
BASE COUNT         6272 a         2723 c         4247 g         6220 t
ORIGIN      
        1 taggatattg ggaagattcg cttcttccga taaagtctct aacactttca cgtcatggac
       61 acctggattc gtgattgagt aagtaatcgg aaagccagtc ttagtaacga tcatatgaat
      121 tttaagacca taaaaataag atttttttgt tgatttacca acatgtttag acattttcct
      181 ctaggaaaaa attaactagc accacgggtg atatatatgt atatggtgac tgaagacaaa
      241 aaaacagaac taatgaaact gaataaaaat atagagtgaa ctagtttcta agagggattt
      301 taaactagat ttcattggta ataaaatttg gagagatgga aaaacagcac ttaaggaagc
      361 agattttgtt gtcatttttg ttcctacaaa ctatggtagt gaatgtgtta ttgaattagt
      421 gatgtctgtt atttcagagg cattggggat aattaaatcc actatacctg taggatatac
      481 aaaaagtgga agaaaaaaat attatcaata gattttattt agttcagaat ttttacgtga
      541 aagtagatta ttaatgataa tctttatcca attagaatta ttatcgtagg atgtgatgat
      601 gaaagccgtg aaattgttca agtatttacc aatgtctccc tgccagtaaa tccgcttaga
      661 atttgagcct tgaaaatgtg caatgataaa aaacaaaaac tcgctcaaaa tagacagttt
      721 ggggtgggaa tagaccaata atgtaccaga caaacttcca tttggggtga aaataggtca
      781 ataaagcgat gttaaacata cctttggagt aagaatagag ggtaataagt gaatttataa
      841 actttttggt gactggttga gtggaaaatg taggtacatt tcaatgcgaa aatgtattat
      901 aaccccaaac gaggtcaata aaaatgactc aaacttgcaa tataacccta aacgggtagg
      961 ggatttatga aaaattgaat ttgccggcgt aggagctggc tgttttaagt atgaatgaac
     1021 acagctttcg ggctgtttta tataaatagc aggttactgt tcacaaacag cattttgtta
     1081 agaaagtagt gaccacagca gtggtggaaa gaggaaatat tatgaagaaa cagtataaca
     1141 ttgcagtcgc cggcaccggt tatgttggtt tgagtattgc cactctgttg gcacagcacc
     1201 ataaggttac agcggtggat atcattccag agaaggttga actgattaat aaccgtaaat
     1261 ctccaatcca ggatgattat attgaaaagt acctggctga gaaagaactg aatctgaccg
     1321 caacattgga tgcaaaggca gcataccagt ctgcggattt tgttgttatt gcggctccta
     1381 ctaactacaa tagccgcact caacattttg acacatccgc tgttgaggct gttattaggc
     1441 tggtcatgga agtaaatcct gatgccatta tggttattaa gtccaccatt cctgttggat
     1501 acaccgcttc tgttcgtgta aagactggta gcaagaatat tattttcagc cctgagttcc
     1561 tgcgtgaaag taaggcactg tatgacaatc tgtatccttc gcgtattatt gtgggtaccg
     1621 atatggatga tgagcgtttg gttgaggatg cacacacttt tgctacactg ctacaggaag
     1681 gcgcaatcaa agagaatgtg gacacattgt tcatgggctt tactgaagca gaagctgtta
     1741 agctgtttgc caatacatat ctggctcttc gtgtcagcta cttcaatgag ctggacactt
     1801 atgcagagat gaaaggcttg aacactcagc agatcattaa tggagtttgc cttgatcctc
     1861 gtattggtac tcattacaac aacccttcct ttggttacgg tggctattgc ctgccgaagg
     1921 ataccaagca gcttctggcc aactacgcag atgttcctga aaatctgatc gaggcaatcg
     1981 ttgaatctaa ccgtactcgt aaggacttta ttgcggatcg tgtacttcag atggctggtt
     2041 attacaatta cgcagaagca aatcagtatg atgctggcaa agaaaagcct gttgtgattg
     2101 gtgtttaccg tttgaccatg aaatccaatt ctgataactt ccgccagagt tctatccagg
     2161 gcgttatgaa gcgtgtaaaa gctaaaggtg caactgttgt gatttatgag ccgaccttga
     2221 aagatggaga gactttcttt ggcagtaagg ttgtgaatga tttggaacag tttaaggcaa
     2281 tgtgtgattc tgttatagca aatcgctacg atgcttgcct tgatgacatt aaggaaaaag
     2341 tatatacccg tgatatcttc cagagagact aagattagga gagagtattt atgattatta
     2401 caaaaacacc gtttcgtatg tctttttttg gcggtggaac ggatatggag gattatttca
     2461 aagagaatgg cggtgcagtt ctttctacta cttttgataa gtactgttat gtgaatgtga
     2521 gacatctgcc tagatttttt gattacagcg ctgagttatc ttattctcgt actgagagag
     2581 taactagcat tgaagatatt gagcatcctg cgattcgtaa tgcgatgaaa atgctcgatg
     2641 tgcatgaaat tcggcttaca tacgaagctg atttacctgc tcgctctggt ctgggtacat
     2701 ccagttcttt tgcagttggt atgttgaatg ctttttatgc actggagggt aagtatgctg
     2761 acaagaagaa acttgctgat gaagccattt atcttgaaag agttctgtgt aatgaagccg
     2821 gtggatggca ggatcagatt gccgcatctt atggtgggtt caatcgaatt aatttcaatg
     2881 tggatggtta tgaggtgctg cctgtcatta tttcgcctga acgtaaaaag cagcttaaca
     2941 acaatctgat gatgttcttt accggattca ctagattttc ttctgatgtt caaaaggcta
     3001 acaacgtcag tggcacagag gataagagag taagactgaa aaagatgtat gagcttgtag
     3061 atgaagctga ggcaattctt actgataaga acagaaattt agatgatttc ggtagacagc
     3121 ttgatgttac ttggagattg aaaaaaggta ctggtggagc aattagtaca ggaagcattg
     3181 atgaactata tgaaaagggt atggctgcag gtgctttagg cggaaagttg ctcggtgcag
     3241 gtggtggagg tttcttggtt ttctatgtac aacctgagaa acaggatgca gttcgttggg
     3301 ctatgcgtga tttgatgtat attccgtttg aatttgaaga tggtggaact agagttattc
     3361 actacacgcc ggaaacttat attgaaaaac agaatggata aggagtaaca atgttagcgg
     3421 aaaaacttaa taaacatatt gacttattga ttaaacgata tcctacactt gagacgatta
     3481 aacaggacat tatcgatgga tacctaatta tggaggaatg ctatttgaat ggtggtaaac
     3541 ttcttgtggc aggaaacgga ggatcagccg ctgactcgga acatattgct ggcgagttga
     3601 tgaagcggtt taagacgcca cgtcctgtaa gtaaggaatt tgccgataag ttagttgcaa
     3661 ttgaccctgt aagaggtccg gaattagcca aaaatctcga gtgtggttta acggcaattc
     3721 ctttggtcgc acacgaagca ttgtctactg cttatattaa tgatgtcgat ggtttgggtg
     3781 tcttcgcaca gcagctgttt ggctttggta gatctggtga cgtattcctt ggtatttcga
     3841 cgtccggaaa tagcaagaat attatgagcg caactgttgt tgctagggct ctcggtataa
     3901 aagttattgg cttgacgggc gcaaagggtg gggaacttgc cacggtagca gatgtttgtg
     3961 ttaaggctcc tgaagttgaa acatacatga ttcaagagta tcacttgccg atatatcatt
     4021 gttggtgttt gatgctggaa gataaattct ttggaaacga ataaaatttg gaggaatgtt
     4081 aaatgaaaaa gacaattatg gttaccggtg gttgcggtat gattggctcc aatcttgtta
     4141 agagactggt gaaggaaggc tgctgggatg tttatgtagc tgataatctg tggagaggaa
     4201 agttggagta cctgaacgac gaagatgggc atcctgtcat cgacctggat actcatttct
     4261 tcaatgctga tctgactgat tatgagcagg ctaaaaaggt tattggtacg actgagtatg
     4321 tagttcatct ggctgatgtt gtggctggca ttgactatgt gtttaagaac cagggcgaat
     4381 tgttccgaat caataatctg atcaattcta atgtttttga ttgttgccgt aaggctggca
     4441 aggagaaaat caagggtgtt atctatgttg gtaccgtatg ctccttccct ctgaccagac
     4501 agaatacttt gaatcctgag cctctccggg aagaggagtt gttccctgct cttcctgagt
     4561 ctgcttatgg ctggagcaaa ctgatgggcc agttggagat ggggtatttg gaaaaagaaa
     4621 ccggaattcc gtgctgtatc ctgatgcttc ataatgttta tggcacacct actgattttg
     4681 gcgaacgtag tcaggttatt cctgctctga ttcgtaaagc aatcaataat cctgaagagc
     4741 cttttaatgt gtggggtagc ggagagcagg gacgtgcttt cattcatgtc aatgatatcg
     4801 taaatgcatt ggtgctcgcc ctggataagg gttggggtca tggtcatatt cagattggcc
     4861 cttctcactg tacttccatc aaggaaattg catataagat cattgaaatt tctggcaaag
     4921 acatcaagcc tttctttgat acttctaagc ctgaaggtga taaggctcgt tgcgcagatt
     4981 attctaaggc gaaagagatt ttggattgga agcctactgt ttctttggaa gagggtcttc
     5041 gtgaatccta caattggatt gaaaagcaga ttaagggtta ataagtatat aagctgttct
     5101 tcctccgtgt aattagagga tgcggaggaa gaacatatga gtaaggatgt actgagatgg
     5161 aaaagaatat gtataaaaga aaacgtgatt tcactgtgtg tggaatagta ggtgtttgtg
     5221 ctactacaaa gaacgagttt gtaagggaag ttttttccat gccaacatct ccggtaagtg
     5281 cgactgttga tctcgtggga gtgccggcca ttatttcggc aaaggaaaat cccaaaattg
     5341 ctgagatgta tagccaggct acaatggctg caatagatgg tatgcctatt gttaaaattg
     5401 gacggcgcaa aggatttacc tgtgaacgat gtgctgcacc agatattatg ggaatggttt
     5461 ttgaagaagg cgttagacag ggaaaaacac attatttcta tggtggaaaa gataacgaag
     5521 tgttaaataa gcttcgtgca aacctagaaa gagattaccc gggaatcaaa attgttggaa
     5581 tgtattcccc accatttcgt ccgttaaatg aagaagagga tagcaagatt tgcgaggaaa
     5641 tcaacaactt aaatccagat tttctgtggg ttggtattgg tgcgcctaag caagaaatgt
     5701 ggatgtggga acaccagaag aagatccata acacagtaat gttcggtgta ggcgccggct
     5761 ttaacttttt tgcgggcact ttggaaaaag ctcctgaatg gatggaaaaa gctagtctag
     5821 agtggttatt tagactggta aaggaacctc gtagactatg gaggcggtat atcttgggag
     5881 gtataaagta tatctactat actattgaat ctaagtaggg gggcaataaa aatagatgaa
     5941 aatacttata gtagttacaa tgacgaataa ctttggtaag aaggggtcct ataattctca
     6001 ggaaatagga ttagctcgag ggttagctga attaggccac gaagttattg tatataaaag
     6061 tgtaaaaagt gatgaggaag ttggaacaga gcaattaagc aatacggcga tgattcacta
     6121 tatcaagtgt cgttatgtag gatcaaatgg attcttatca acaaagaatt ttgataagaa
     6181 tgcggatgtt ctaatacaat ttgcggacct tcaactatca gtacctcatg tatactcatg
     6241 gactgtaaaa aatggaataa aatatatacc ttataatggg ataacgcgaa gtcaaagtgg
     6301 caataaatat ataaagacaa ttattgaaat attggcgcat cgaaattata aaatttataa
     6361 gaaaaatggg tgtgttgcca aaaatgatcg agtttctgaa aaattagtac aattaggagt
     6421 aaataaagtg aaacttgctc ctgtttgtgt ggattttgaa cagttacata agaattacga
     6481 agcaatagat tttactactc tcagagaaaa atggaatatt cctcgcgatg ttcgtgttat
     6541 tttatatgta ggacggtttg aaaaggataa aagaccgtta gatatgatta gtttatttaa
     6601 taaacttgat gagcataatt atttgctgat ggtaggaact ggtgctttac tcgagcaaac
     6661 gaagcagcag ataaatttac ttggactgca gaatagagta aaaataattg agcgtattcc
     6721 taacaaagat atttgggagt tatattgctt atcggatgta tttgtaaatc taaactatac
     6781 tgaaatttgg ggtatggttt tgctagaggc aatgtactat cgcctcggaa ttattgctgt
     6841 taatgcacct ggcccacaga atattatttt ggataataga tatggaatgt tggctaaatc
     6901 tgacgatgaa attttgacat tcttaaaaga cggacgattt accaacgata tcatagatgc
     6961 agcatatcag cgtgtaacta cagaatttag atggtcaaag tcgggagaaa ttatgcttag
     7021 catgttggaa ggtgataaat gatatggaag taacgaaatt aatggcattg aggaatcgat
     7081 atgctttaaa catagttgat aattgcacga gaaaaatagc caaaattctt ggttgttgta
     7141 ttggtaaagg tgcacagata gggaactctg ttgaatttgt tcataattct gtaggcactg
     7201 tgattcattc tgacacaatc cttgaagatg gtgttaaagt ttatcagaat gtgacgtgtg
     7261 gttgagcaga tagtaatgaa cgtatcatca ttcgagtaaa aaagaacgct gttttatgtg
     7321 tgggtgctaa aattctttgt aaatctaaca cagaattatg cgttggggaa ggtgctgtag
     7381 ttgctgcaaa tacagtggta ttgaggtcta ttccacccta cgaagtgtgg ggggtacctg
     7441 ctaaaaagat ggggagataa aacatgaatg catataaatt atacaaagta gaacgatggt
     7501 tttacttaca caaaatggag ttttttgcca agattgtaaa ggcactaatt tatgtacttc
     7561 ataatagctc aatttcatat caaacagaaa ttggagataa ttgtaagttc ttatacggtg
     7621 gcataggttg tgtaattgga aaagatacaa aaataggtaa tcacgttata atcggaacga
     7681 atgtactgac tggtggtaga tccaataagc ctggtatgcc tacaattgga aacaatgtat
     7741 atatcgctac tggcgcaaaa attttaggta atatcacaat aggggacaat gtaatagtag
     7801 gggctaatgc tgtggtcatt aatgatgttg aacctaattg ttcggtagga ggcgttccgg
     7861 ctagagtatt gaaaaaagat attgatgtaa atgattattg tagtttgaat cgttactaaa
     7921 aggagagatt gtatgttgta ttttgttatt cctttaatga gtgcgaaggc agcaaacaat
     7981 tgggagatgg ttagtacctt atttaaccga acattatggt cgtgttataa tcagactgat
     8041 cctgatttca aaatcattgt tgcttgccat gaaattccta aactcacgca tgaatatgat
     8101 gacagagttg aatttattca agttagcgaa aaggatgccc ctattcccac aaatcaagac
     8161 gaaaaaatga ttgataaggg ttataaaaca catgctctcg caatgcgttt gcgagagttg
     8221 ggcggcggtt tcgctatgat ggttgacgca gatgatcttg taagttctca tttggcggaa
     8281 tatgtgaatt cccatcccca ggaaaatgga ttttatgtca aaacgggata cgtgtacttt
     8341 gttggagacg attatatgaa ggttctacca aagttctcat caggaagtgc gtgtatagta
     8401 aaatatgcag tggaagacct gcctgaggca tatccggaag ttatgacagc aaattgtgat
     8461 gataatccat ggatcattag aaaacgacat gggggcgttg ttccagcatg tgaagagcaa
     8521 gggcgtccat taaaacctct tccattcaaa gcagcagtat atgtattagg aacaggggac
     8581 aatcactcgc tttatggtaa aacgacaaaa tatcagacga agatgcgaga gatactggaa
     8641 atgtttatag caaaacgtaa aattaaagga aaactgaaag cagaattttc tgttgattgg
     8701 ttataaggtg agtattatga aggtattgat gtgtgaaagc caaatgccag agaattggta
     8761 ttcgtttgat ctttctaaag aacttaatca atatgttgat ttaacattgc tgtgtaagcg
     8821 tgatgttcct cctttagatc ctaaaattaa gagcaaacat attttgtatc ataaaagtac
     8881 aaataaagtg ttttcggcac ttgtttttct gaaaagcttg ttcttaattt ggaaggaaat
     8941 aagatttggt gattatgata ttgttcattt gcaattgatg aaaagtctca aatatgaagg
     9001 cggattgtac gttttatgta agagacacta taaaaaatta attatgacag ttcataatgt
     9061 gttaccacat gaggttcgtg aaaaggatcg ccaagagcac tttaatatat attcaaattg
     9121 tgatggtttc attgttcaca atcgagtaac agaacagcat ttatatgctg aattcccaga
     9181 attaaatgca aagtcatatg tttgtccaca tgctatctat ggagatgtta aacatatatc
     9241 tagagcgtat gataaagata agtttgaatt tatcttgttt ggacaaattc gtccatataa
     9301 gggaattgat gtactgctta atgcaatcac agaacttcca atggatgtaa gaaagaaagt
     9361 tcattttacc atagcaggtc aacaacatcc taaacaggat agtactgact ataaaaaaat
     9421 gattgaagat ttaaaggttt cagattgtgt tctatataag ccagagagaa tttctgatga
     9481 agaaatggac agtatgttca gaaatgcaga tgccgcaata tttccatata aagaaatcta
     9541 tggaagtgga gcgcttctta tggcatacac ttattgctta ccaactattg ttagtaatgt
     9601 acctgctttt atggaagaaa ccgaggaagg aaagataggg ttacttttcg aaaatttgaa
     9661 ttctaagagc ctagcagaca caattgtaaa gtatgtgaac cttagcccag ctgagaaaag
     9721 caaaatagag gatgatatat atgagcttgt aaaccgcaag tatacctggg cggcatctgc
     9781 aaaactcaca tacgaggcat acaaacaaat tttgaatgag tagtaaaaca attagaaagg
     9841 aataataatt aacatgcaga ttagtaaatg gaaaatcata cagtttctaa tggtctttct
     9901 aatgattatc tcatcaagca tattgaagcc tttgggcggc tggttgggag aaacgatgaa
     9961 cgttagactt gtgacagtca ttctagcaat agtatgtttg ttaatagcct cattaccagc
    10021 atttagaaaa aatagatatt taaatttctg cactttactg atttgtgttg ttataatagc
    10081 agcttacatc tactcagata agacaatatg ggttaaatct agggaaagta tgagtttata
    10141 ctatgtatta ttggcgtatc cattgttctg tactttaatt aaccaagcgt ggaatttgga
    10201 ttcaatgcta aatacgatat gtggtgtaac atttctttca tacattctta gaacatctat
    10261 ttcacttatt cagaaatttt caggagtact tctctatgaa aacatatatc gtgagtgtgc
    10321 cccggaaaat tggtatcgtg gaggcttttt aagaattaat ccaccatgtt ttacaattat
    10381 aataataccg attgctttgt atatgattga gcgacaagtt gtagctagaa gaaaagtaaa
    10441 atattattta ctgattgcta gcgcactggc atattctgct gttattcatg gttctagatc
    10501 tgtccttgtc tatcaaatta ttgtacttgg ttgctatatc ctttttaaga aaggttcttc
    10561 gaaaagaaaa attgcaatgt gggttttagc tgggttgctt gtagtcatat ttattaattc
    10621 gaccatgttc tcaacatttg ttgaaacttt cacaaacagt acaggtgaat atgcaggatc
    10681 tgctgaatct cgatttgctt cagtttggtt ttttgttcct aaatttttgc aatcgccttt
    10741 gttcggtact ggtattctta ctggtgagga atttacgttt atattaccag gaggagttag
    10801 aggacaccta tctgatattg gatttttcta tacaattact caatatggtg taggtatact
    10861 tatatttgat attctgttta ttataaaagg gttcaaaaca gcattacttg catcaaaagt
    10921 gggtatgact ggctatcaat atttagcatt tggaattaca ttaagtgttt tgctaacagg
    10981 gattaatata gactggtttt atccgatatt tactccagct attcctgtat gcttagcggt
    11041 tatagaatac atctatcaag aatgtagaag tgtggctaac atagaatagg aaatattaat
    11101 aggagtgcat ctcatgaata agaaagagat tttatataac atattgaaga agtacgaaaa
    11161 tttaccatat gtgtttagga acatgtttgg tcataatata agtaaactcg tatcttggaa
    11221 attgactgct gattgtgcaa cagtagaaga aaattctgaa gtttatgcag cgtttcaatt
    11281 gcgctcaaag gacatgtctg atgttccagt gatgggttta gttaattgtt gcaaagatgt
    11341 agcaattgta atgcaggggc cactatgttt aaaggatgat ttctcttata atactctggc
    11401 ctactataag aaatgttatc caaatgcttt aattattctt tcgacatgga aggacgaaga
    11461 tattaaggca ttgaaaagga tagaggatct tggagttata gttatttgta gtgagaaacc
    11521 tgaaaagcct ggacacttaa atattaatta tcaagttgga aacactttgc ctggaatagt
    11581 cagagcaaag cagcttggtg caaagtatgt ttgtaaaact agaacagatc aaagaatata
    11641 ccatccaaat gcaatggcgt ttttctgcag tttacttgaa cagtatcctg ttaataacga
    11701 agatgattgg aaattaatac aaaatcagcg attactgtta ctatcaatgc cgtatggaga
    11761 catgtttttc ccgtattgtt tgtcagactt cctgtatttt ggtgatgttg atgatatgat
    11821 aaacctcttc tcgattccta gtgatgtgag agaaaaggga gctgtgtcta gaggagtctc
    11881 aagaagggag atatctgaaa ataatttagc tccagaagtt cagcttcttc gaagctatat
    11941 ttcacgaatg gggggcaatg aggagtgctc tattagggca tattgggagt ttgtaaaaaa
    12001 ccatgttatt actattaaca aaaatcaaat tgatttgtac tggcataaat atgtaggtcg
    12061 ttattcaaat aatactattt atggtacgta ttatattgat gatagccaag atgcacttca
    12121 ctgctataat tttgatttta taaattggtt gaatttgtac actggaaaat acgaatacaa
    12181 agcaaaatat gaaaaatata tggactttgt ttgggaagag taattaactt ttatagtaaa
    12241 aagtacttta gggaagggca tattatgaaa acagtaatta tggcgggcgg acgaggaagc
    12301 cgaatttcgg aattgtttcc ggatattcct aagccaatga ttcctataga tggcattcca
    12361 gttttagaac gagaattgtg ttcgcttaga gatcaaggct ttaatgatat tattttgact
    12421 gtttcctatt tgcatgaaaa aatagaggag catttcggag atggttcaaa attaggaatt
    12481 aaaatcaaat attttattga aaaaactcca cttggcaatg caggtgcatt gtattttttg
    12541 ttggatgaac tgggtgatga accgttttta cttttgaatg ctgatgcagt atttgatgtt
    12601 gatttcaggc agatgattag atttcatgtt gagaataacg cagatgttac tttgtttacg
    12661 catcctaact cacatccgta tgatagtgga ttaattatat ccgatgacaa taagaaagtg
    12721 cttcaatggt tagcgaagga agatcaaaga cctgaatatt ataaaaaccg agtaaatgca
    12781 ggtcttcatg ttataaatcc gaaggtgttg agagaaaatc cattaatgga aattgtaaat
    12841 aaatcaatag ttgaaggtgg ggggctacca tacaaaattg atttagatag aatgattctg
    12901 aaaccattgg ctaacacagg gcgtatgtat tgctacgatt ctccagagta tgttaaagat
    12961 atgggaacac cggaccgata tagagctgta attaaggact ttcaaaaggg aattattgtt
    13021 ggtaaaaatc tatccaatcc acaaaaagca atctttttag atagagatgg aacgattaat
    13081 aaatacgttg gttttttgag aaatgcagaa gaatttgagt taattgatgg agtatcggag
    13141 gcaattaaga ttattaattc tctaggtttt ctgtgtattg ttataacaaa tcagcctgta
    13201 attgcaagag gtgaagttac tgttgatgag cttaatagta ttcacaataa gcttgaaaca
    13261 atgctagggc atgctggtgg atttttaaac ggtatttatt actgtccgca ccatccccat
    13321 aaaggatatg caggagaggt tatagaatta aaaattgatt gcaattgtcg caagccaaaa
    13381 cctggactgt tattagaagc atcaaaggat tttaacataa acctaagtca atcatttatg
    13441 gttggagata gtgaaagtga tgtaattgct ggaaaaaatg ctggttgtaa gacagtactg
    13501 attacagaag acatcacctt gcctgctaat tatggccaag actatagtgt ctgttcattg
    13561 ttagaatttg ttaaaaatca tttatgcact atgcaataat tggtttagtg aaacttgtaa
    13621 aaggagtaat tagatgaagg tattaattcc agcagcaaaa gttgttgaaa aagaattgca
    13681 gagtatagga atgttaccag caattatcta tccaattaat aaaaaaattg tctttgatta
    13741 tttgtataat cagtataatg caatctgcga ttcattggat attatctgtt atgaaaaagc
    13801 ggataaggtt catagaagac tgaaaaacta tcatgattcc agaattcata tatgtgacct
    13861 tcctgaatta ggggatctag ggcaaaccgt gtattttggg ttatcagatg aagatgagcc
    13921 tgttctaatt aacttcgcag atacaattgt tatggagagt atgtctgata tagaaatgga
    13981 tacattctat tattctgaag attttgtgtc gagtacttgg acatacttta aaattaatga
    14041 aggaataatt actgatatcc acgataaaga ggaagcttac gtatccgata aacgtgaaaa
    14101 attatttatt ggcgtattta tgttttcttc gtcaaaactt ctgaagagtt gcttaagaga
    14161 ggcagttgag agtcggaaac aggggggaat aaactcattt tatcgggctt tacagctata
    14221 cagcgaacgt tgtccgctaa aggccgtaag aacagaaaag tggtttgata ttggacacat
    14281 cgataaatat tacaatacaa agttggaagt taaagcacga gagtttaatc atatctctat
    14341 agataaagat cgagggatat tgaagaaaac tagcgatgac aaggataaat ttattggaga
    14401 aataaagtgg tatttaaaac ttcctgctga tattgaatat gtaagaccta gaatttttga
    14461 ttattctaca tcttacgtag ctccctatgt tgatatggaa tattatgcat atcatacggt
    14521 tcatgagtta tacttatatg gtgatttaaa atataaccag tggcatgatc tgtttagccg
    14581 tataaagttt atctgtagcg attttaagcg atacacctta aaagatgaaa agattagaga
    14641 gtcattggaa gatatgtatt tgcgaaaaac catgcagaga tttcaaaaat tgtctgaaga
    14701 taaaagattt tcagcttttt ttgagaaaca aattcaaatt aatggtcgta agtttatttc
    14761 tttaaccggt gtaattgaac ttctaaagaa tcttatccca agtatgctct atgatgtaaa
    14821 tgaattttgt attatacatg gagatttgtg ttttgctaat atgatggtag attccaattg
    14881 ttcctttgtt aaggttattg atcctagggg aaaatttgga aaatatgata tttatgggga
    14941 cagcagatat gaattagcaa aactatttca tagtttagat ggtaaatatg attatatcat
    15001 caaggatcta tttactgtag aatatgatac cgagtgtgca gtgatagatt atacaattaa
    15061 tacgcgtgta agagattacg atttatttga attgtttaag tcggtctttt cggacgagat
    15121 taaggacgat tttgataaga ttgtattgat agaagcgttg ctatttctta gtatgattcc
    15181 attacacggt gaaagttttg atcaccaaat agtgatgctt gctacaggta tggaacttct
    15241 tgcaagagta agtaataaag ttatactcta atataaattg tgccttaatg aataacggtt
    15301 acaatactgt tttagcaatg taggcattaa ggcacgatta tattaattaa tacaatagaa
    15361 gggaagagaa aaatgtatag tgaatattct tttgtgtttg atatcgatgg cactttgtgt
    15421 ccgataaaga agaaggatga gcgatatgag gatttggtgc cgtatgagaa tatggttgaa
    15481 aaactgagat tctataagga gaatggtgct aaaattacat tgttcacctc acgcaatgtt
    15541 aattcctata aaggaaattt gggaatgata aatgctaata ctgcaaaagt gctcttggcg
    15601 tggttggata aatgggacat tccgtatgat gaaatcctgt atggtaagcc ttggccgggg
    15661 cataaaggct tctatgtaga tgatcgaacg gttagacctg atgagttttt gagatgctct
    15721 gtagatgaat taaatgaaat ctgcaacagt tcaaaaaaaa gattctaaat aaggaggtta
    15781 gttctatgga aaaaaagatg acagttatca ttacgatggc aggtttggga agtcgttttc
    15841 gaaaaattgg ttatgcggtt cctaaatata tgattaatgc caaaggaaga actttatttg
    15901 attgggccat ggatagtttg gttggataca ataaaaatgt tgataagtat atttttgttg
    15961 ttcgtcagga agacaacgct tcagctttta taaaggagca ttgtgcttac tttggtattg
    16021 aaaacgtaga agtgattgaa atagactata tgacagatgg tcaagcaact acatgtatgt
    16081 tggctattcc ttattgcaat caagacaatg agattatggt ttacaatatt gatacatacg
    16141 tggaatcaaa tgagatgaaa tacgaagata tttgtggaga tggacatatt ccatgctttc
    16201 atgctgatgg cgatcattgg agttttgcaa agcttaacga tcgaaatgaa gtaatagaag
    16261 tccgcgaaaa agttcgcatt tctgataatt gtactcttgg tgcgtattat ttctcatcgg
    16321 caaagctgta taaagcttta tatgaagagt attatgcaga ctcctctaat atggagaaga
    16381 atgaaaaata tatagcacca ttatataact ttatgataaa aaaagggtta aaggtgacta
    16441 ttagcatagt agatgcgaaa aaggttcatg tgcttggtac tccagaagag ctcaatgtgt
    16501 ttttgaatca agaataaata gtgtttagga gaaaatagca gtgaccagta ataatctaat
    16561 tgtaaaaaca ttaagcagat ataagaatac tccacttcct gttaaggctg cattatggtt
    16621 tatggtatgt ggttttttac agagaggggt ttcaatgatt acaaccccaa tttttactag
    16681 agttttgtct acagaacaat acggtttata cagcacttat ctatcgtggg aatccttatt
    16741 gctcatgatt acatcgctta gtttgttcaa agccatgatg aatctttatg taaaatatga
    16801 taatcaagaa catattcttt cgacagtatc cggattgact ttagtactga ctattttttg
    16861 gtttgttatt gctattttta ttaaggatat attggcagaa attttaggat tgacaccagt
    16921 tctagttgtc tgtatgttct catattttat atttcaggca gaaatacaat gttggtcttt
    16981 acacaaacga tatatatatg attataagac tttattagta gctacccttg cagttactgt
    17041 tggctcatct gtagttggct gtttagcggt tctgtttata tctcctaccg ctgaggcgag
    17101 agccttaatg aatgtcctag tgactggtgt tgttggcgtg gctgtgtata tatcggtatt
    17161 tagaagatgt aaggatttta aggataatga agtgtggaat ttcgcagtag tattttgtgt
    17221 atcgttgatg ccacactatt tatctgaatt tattctgaat ggttctgata aaattatgat
    17281 aaattactta tgtggttcgt cagatgttgc tatttacagc gtggcatatt ctattggtgc
    17341 tctaattaac cttgttacaa attctgtcaa ttccactttt gcaccttatc agtatcaaaa
    17401 aatcaagtca ggagaatatg atttactatc aaaaagagct aatgaagttc ttggtttggt
    17461 agcggctatg ctttttgcat taatgctatt tagtaaagaa attgtgttga tatttggtgg
    17521 gcagaaatat atcgacagtg ttaatttaat tgtacctata tgtatcggta tttatttcaa
    17581 ctatatgttt cagctgtttg ctagagtaca ggaatacttt gaaaagaaac tcactgtcgt
    17641 tattccatcg gttttgtgtg caattatgaa tattgtacta aattatgttt ttataaagtt
    17701 atatgggtat caggcggtag catacacaac tgtattctca tatatgtttt tctgcgtcat
    17761 ccattatatt ttttatagaa aagtttgcaa agaactattg gatggaaaaa acatatatga
    17821 tgtcagagga atacttttga tttctgcaat cacgatagct ggtggcatcc taatttcaat
    17881 aattaataaa tttgatttca taaaatattt aattatagca attgcttgtg tcgctgcaat
    17941 tatatttaga aaacgattgc tacttttagt aaggagaatt atgagcaaat aaacatttgc
    18001 tcatagagag atagagaatg atagatatta tttctgctat aatggtaaat gtattaacag
    18061 cattatatca gccgttctta tttgccgtat taacagcgta tctgtttatg tactggtatc
    18121 tatttatagt tgataactct cgagatccta aaaacttaaa agattctgta ttaatctggt
    18181 tgagatattt taaagcatct agtaaatttc gcagactctt ttttcttgcg ttttatttta
    18241 ctttgatatt atttaaaacc ttgcttaatc gaaatatgtg gatgaacccg ctttcaaacg
    18301 ttattggaca gtggtcatta tatattatag ataatgctac aggagagagc agattgacaa
    18361 cagaatgcgt ggagaacacg atgctgttta tccctttttg catgttattg ttatggtggc
    18421 gtgacattaa atgtgatatt atacgcacca tctatgttgg gattaagtat gtgtttttat
    18481 tctcattaag tatagaattt acacaactgt tttttaggct tggtacattt caactatcgg
    18541 atttgtttta taacacccta gggggcttaa ttggtgcttt gctatattgg ctattctacc
    18601 gattaaataa gtatatagac ttaaaataga actgctttga attttaatat ggttaatatt
    18661 tttctgcaga caggattgtg taatctcatc aagaatactt tacatgccat ctatttttgc
    18721 taaaacattg ttgttatatc ttcaagaggt agggaatttt attgctttaa atgaggtcga
    18781 gcgaattaaa aaattggtaa aatatataac atggtggtag ttatggtaaa agtgtttgat
    18841 ataattaagt tttcggattt cagaggatat actgctgttg cattggataa tgagactctt
    18901 ttctcgattg gtattgagtt tcacattaag caaataaatc aaggatttag tcataataaa
    18961 tatactatgc gagggctaca ttatcagagt ggagagcatg ctcaaggaaa gatagtgatg
    19021 tgcctacatg gtgaaattat gaatatcgca cttgatattc gacaaggatc ttccacttat
    19081 ggatgtgtgt atgtcaacac attgagtgaa agcaatggta aatgtgcgta tatcccacgt
    19141 ggatatgctc atggctatct tactatggag gacaatacgc tagttcagtg gtgcgtagat
    19201 aatgatttca attctaatgc tgccaaatgt ataagttatg aaagcgtaga tattgaatgg
    19261 ccggtcagtc ggcagtgttt cgttataagt gagaaagaca aaaatgggga aagattaagc
    19321 ttttgattaa aatgagctgt ggagaaaaga aggatactgg aaaataagaa gaacaataac
    19381 cgagcaaatg ctcggttatt tctatgagga atacataaaa ctaaatttag atatagatat
    19441 ttattcacga aaaactaata tt
//
LOCUS       DAFEEZ010000054        19345 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000054
VERSION     DAFEEZ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.056"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..303
                     /locus_tag="LP245_002059"
     CDS             <1..303
                     /locus_tag="LP245_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1519959.1"
                     /translation="EAYPFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLL
                     TYEEGITNAMIYPYSNGKIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
     gene            complement(499..1797)
                     /gene="eno"
                     /locus_tag="LP245_002060"
     CDS             complement(499..1797)
                     /gene="eno"
                     /locus_tag="LP245_002060"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBL1519960.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(1913..2668)
                     /locus_tag="LP245_002061"
     CDS             complement(1913..2668)
                     /locus_tag="LP245_002061"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBL1519961.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYETGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(2772..3962)
                     /locus_tag="LP245_002062"
     CDS             complement(2772..3962)
                     /locus_tag="LP245_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBL1519962.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(4072..5073)
                     /gene="gap"
                     /locus_tag="LP245_002063"
     CDS             complement(4072..5073)
                     /gene="gap"
                     /locus_tag="LP245_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBL1519963.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(5114..6205)
                     /locus_tag="LP245_002064"
     CDS             complement(5114..6205)
                     /locus_tag="LP245_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBL1519964.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            complement(6354..7688)
                     /gene="rpoN"
                     /locus_tag="LP245_002065"
     CDS             complement(6354..7688)
                     /gene="rpoN"
                     /locus_tag="LP245_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBL1519965.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            7748..7819
                     /locus_tag="LP245_002066"
     tRNA            7748..7819
                     /locus_tag="LP245_002066"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7781..7783,aa:Arg,seq:ccg)
     gene            complement(8011..8895)
                     /locus_tag="LP245_002067"
     CDS             complement(8011..8895)
                     /locus_tag="LP245_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBL1519966.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(8982..9881)
                     /locus_tag="LP245_002068"
     CDS             complement(8982..9881)
                     /locus_tag="LP245_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBL1519967.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            complement(9898..10404)
                     /locus_tag="LP245_002069"
     CDS             complement(9898..10404)
                     /locus_tag="LP245_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBL1519968.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            complement(10593..11213)
                     /locus_tag="LP245_002070"
     CDS             complement(10593..11213)
                     /locus_tag="LP245_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBL1519969.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            complement(11289..11726)
                     /locus_tag="LP245_002071"
     CDS             complement(11289..11726)
                     /locus_tag="LP245_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBL1519970.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            11889..12719
                     /locus_tag="LP245_002072"
     CDS             11889..12719
                     /locus_tag="LP245_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBL1519971.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            12703..14070
                     /locus_tag="LP245_002073"
     CDS             12703..14070
                     /locus_tag="LP245_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL1519972.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            14089..14898
                     /gene="yidA"
                     /locus_tag="LP245_002074"
     CDS             14089..14898
                     /gene="yidA"
                     /locus_tag="LP245_002074"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBL1519973.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(14941..15384)
                     /locus_tag="LP245_002075"
     CDS             complement(14941..15384)
                     /locus_tag="LP245_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBL1519974.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            15518..15889
                     /locus_tag="LP245_002076"
     CDS             15518..15889
                     /locus_tag="LP245_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1519975.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            complement(16058..16840)
                     /locus_tag="LP245_002077"
     CDS             complement(16058..16840)
                     /locus_tag="LP245_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBL1519976.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(16837..17808)
                     /locus_tag="LP245_002078"
     CDS             complement(16837..17808)
                     /locus_tag="LP245_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBL1519977.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            17900..19294
                     /locus_tag="LP245_002079"
     CDS             17900..19294
                     /locus_tag="LP245_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBL1519978.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
BASE COUNT         5492 a         3972 c         3435 g         6446 t
ORIGIN      
        1 gaggcgtatc ccttttttca tgaattagtt gaagcctttc gagacaaaga ccctgactta
       61 tttttctcct tattggcaga acttcccgaa acgttagatg acagctttcg ggaaaagctt
      121 caaaaccttc tgacctatga agaaggcatc accaacgcaa tgatctatcc ttattccaat
      181 ggaaaaatag aagcgaagaa tacccacata aagacaatga aacgagtatc ctacggattt
      241 aaatcatttg agaacatgag aattagaatc tttttgatca atcaattaat caatgtaaga
      301 taacaaaaaa tctgagccag aatgtggttc attctgactc agatttgatt ttgcacaact
      361 catcagtcct tattgacaaa gagccaaaaa actctctacc tgctgatatt tcagcaagta
      421 gagagttcga ttacttaact aagtgatcat actcgactat ctttcaatag tcgatcatgt
      481 atcttcatta gaaaagaatt atttgttttt taagttgtag aaagatttca aacctttgta
      541 ttctgcaact tcaccaagtt ggtcttcgat acgtagtaat tggttgtatt tagcaatacg
      601 gtcagtacgt gatagagaac cagttttgat ttggccagca tttgttgcaa cagcgatatc
      661 agagattgtt gaatcttctg tttcaccaga acggtgagat acaactgctg tgtagccagc
      721 ttctttagcc atttcgatag cttcgaaagt ttctgttaat gtaccgattt ggttcacttt
      781 gataaggatt gagttagcaa ttcctttttc gataccttca gataattttt gagtgtttgt
      841 tacgaacaag tcgtcaccaa ctaattgaac tttgtcgcct aatacgtcag ttaatttctt
      901 gaatccgtcc cagtcgtttt cgtctaatcc atcttcgatt gagatgattg gatatttaga
      961 aactaattct tcgtagaatt tgatcatttc gtcagttgtt ttttcgcctt cgcctgagtc
     1021 agctagtacg taaacacctt tttctttgtc gtagaattct gaagaagcag catccatagc
     1081 aagaacaacg tctttaccag gtacatagcc agctttttcg attgcttcga tgattacttc
     1141 aaaaccttct tcgtttgaac caaggtttgg agcaaatcca ccttcgtcac caacagaagt
     1201 tgctaatccg cgagctttca agattgaagc taatgcgtgg aatacttcag cacccatacg
     1261 tagagcttct ttgaatgttg gagcgccaac aggcatgatc atgaattctt ggaagtcgat
     1321 tgagttatca gcatgtgatc cgccgttgat gatgttcatc attggtgttg gcaatacttt
     1381 tgtgttgaat ccgcctaggt agtggtataa aggtacttct aggtagtcag cagctgcacg
     1441 tgcaacagcg atagaaacac ctaaaatagc gttcgcacct aatttacctt tgttaggagt
     1501 tccgtctaaa gcgatcatag ctttgtcgat agccatttgg tcacgaacat cgtagccaat
     1561 gattgcttca gcaatgatgt tgtttacgtt gtcgacagct ttagttacac ctttaccgcc
     1621 ataacgagct ttgtctccgt cacgtaattc aactgcttcg tattcaccag ttgaagcacc
     1681 tgaaggaacc attccgcggc caaaagctcc gctttctgtg tatacttcta cttcgattgt
     1741 tgggttacca cgtgagtcta agatctcgcg agcgtaaaca tcagtaataa ttgacatgtt
     1801 ttgtctctcc tttgagtttg ttttttccta agggatttcc ctcatatacg attttagtta
     1861 attttgctca ttagtgcaaa catttcttgc atttttcgca aattttcaac aattatttta
     1921 cagcgtctaa caatgacaaa aatgaatctg cttgcaagct tgcgccaccg actaaagcac
     1981 cgtcaacatt ttcttttgcc atgtattcag caatattttc tggttttaca gaaccgccgt
     2041 attggatacg aactgcttct gatacttctt ttccataaag tttttcaact gtttgacgta
     2101 caactccaca aatttcgtca gcgatttgtg cgtcagctga tttaccagta ccgattgccc
     2161 agattggttc ataagcaata accatgtttg acacttgttc agctgaaaga tcagctaaac
     2221 cagctgtaat ttgtccttcg atccattcag cagttttgcc tgtttcatag gtttctaaag
     2281 attcgccgca gcataggatt ggtgtcatac catttgcaaa gatagctttt gcttttttat
     2341 tgatgtcttc gtctgtttca tggaaatatt cacgacgttc tgaatgtccg atgatcacat
     2401 aatgaacacc tagatcagca agagctgctg gtgaagtttc accagtgaac gcacctgagt
     2461 tttcccagta gcagttttgt gctgagattt ttagttctgt accttcagct gatgtcatta
     2521 attcttgtaa gaataatgca ggagatccga tgactgaatc aactttgtca tttgaaggga
     2581 ttttgttttt tactgcttca gcaaattctt ttgcttctga tgcagttttg ttcattttcc
     2641 agttacctgc gataataggt ttacgcattg aggaacacac tccttaattt attgaaaaat
     2701 ggctagggag tcatgaaaac tcccttcacc ttttgatcga ttactcgtca gaattgagca
     2761 aacttggtcg tttatttatc gttgattgct gctagtcctg gtaattcttt accttcaagc
     2821 aattccaagc ttgcgccacc acctgttgag atgtgtgtga atttgtcagc aaatcctaat
     2881 tgttctgctg ctgcagctga gtctccgcca ccgatgattg ttgttgcgcc ttctaagtta
     2941 gcgattgctt cacaaacacc gattgtacct ttagcaaagt tactcatttc aaatacaccc
     3001 ataggtccgt tccaaacaac tgtttttgca ccttgtaatg tatcagcaaa taattttact
     3061 gatgctgggc cgatgtctaa agccatcaaa ccatcaggaa tgtctccttc gattacttgt
     3121 gtttcaacat catttgaaaa ttctggtgca cagacattgt cgattggcaa gacaagtttg
     3181 tcgcctgctt tttcgattaa ttcttttgct agttccactt tatcagcttc tactagagag
     3241 ttaccgatct tgattccttt tgcttcgtag aatgtgtaag tcattccgcc accgatcaag
     3301 attttatctg ctttaggaat caagttttcg attacgccga ttttatcaga aacttttgcg
     3361 ccaccaagga ttgcaatcat tggtcgtttt ggttcttcta ctgcttcacc gatgaacttg
     3421 atttcttttt ccatcaagaa tccagcaact gttgggatac cagttgaagc gatacctacg
     3481 ttagaagcat gtgcacggtg agctgtaccg aaagcatcgt taacaaatac atcgcctaat
     3541 gaagcccagt atttacctag ttctgtatca tttttgcttt cttttttacc gtcaatatct
     3601 tcaaatcgtg tattttcgaa tacgacaacg tcgccgtcat tcatgttgcg gattgcttct
     3661 tctaattgtt ctccgcgagt ttcaggtacg aatgttactt ctttacctaa taattcgcct
     3721 agacgttttg caactggagc taaagatttt ccttctttat cttcttctgt ttttacacgt
     3781 ccaaggtgag agaaaaggat tgcttttccg ccttgttcta gaacgtagtt gattgttggc
     3841 aatgctgctt tgatacgagt gtcgtcagtg atcacgccgt ctttcaaagg aacgttgaag
     3901 tcaacacgga caagaacttt tttgtctttt aaatcgatat ctttcactgt tttcttagcc
     3961 attttatttc ctcctgaata aacttattat caaaaaaagc ggaagaagcg cgattgcttc
     4021 cccgctttta aatgtacatg tctataattt acacttgtac gtttgtctat cttataagtt
     4081 agcgaagtat tctaaagtac gtactaattg tgcagtgtat gacatttcgt tgtcgtacca
     4141 agcaacagtt ttaactaatt gtttgtcgcc aactgtcatt actttagttt gtgtagcatc
     4201 aaataatgaa ccgtaagtca taccaacgat atctgaagaa acgatttcgt ctgtgttgta
     4261 tccgtaagat tcgtttgaag cttctttcat tgctgcattg atttcgtcaa cagttacttc
     4321 tttttcaaga actgttacta attctgttaa tgaacctgtt ggtacaggaa cacgttgagc
     4381 agctccgtct aatttaccgt tcaattcagg aattactaaa ccgatagctt tagcagcacc
     4441 tgttgagtta ggaacgatgt ttgcagcagc agcgcgtgca cggcggaagt cacctttagg
     4501 atgaggtccg tctagagtca tttggtcacc tgtgtaagcg tggatagttg tcattaatcc
     4561 ttcaacaaca ccaaatttgt cgttcaatgt tttagccata ggagctaaac agttagtagt
     4621 acatgaagca cctgagataa ctgtttcttt accagttaat gtttcgtggt ttgtgttata
     4681 aacgattgtt ggaacatcgt ttccgccagg agcagagata acaacgcgtt tagcaccagc
     4741 tgttaaatgt ttttcagctg ctgatttaga agtgaagaaa ccagtacatt ctagaacgat
     4801 atctacgcct agttcgcccc atggtaattc ttctgggttg cggttagcta atactttaac
     4861 ttcttttccg tttacgttga atgaaccttc atgaacttca actgttccgt tgaaacgtcc
     4921 ttgagttgtg tcgtatttta acaagtgtgc caacatttta gcatctgtca agtcgttgat
     4981 tgctactact tcgattccat ctacatcttg gatacgacgg aatgctagac gtccaatacg
     5041 tccaaaacca ttaataccta ctttaactgt catttaagat ttcctcctta tgaaaatcaa
     5101 aaaaatattt attttaaagg gttacccctt ttaaaatctc atttgcagca gcttcatcag
     5161 tgatgagcca cgtttgtttt ggtgcatttt tcatataagc tcgaattgct ttagcttttg
     5221 attttccgcc cgcgattgcc atgatgatcg ggactttttc caaatcttgc aattctatgc
     5281 cgattctagg gaccttataa acgacttcac ctttttcatt gaaaaagtag ccaaaagatt
     5341 ccgcaacagc atttgcttgt ttcagcatga ctaattcttt ttcagtcatc ttacgacgtg
     5401 ctgccatgtg taatgcacgc ccaatactat gaataacaca attcgcttca ctaatcaagt
     5461 ttaagacttc ttggatagat ggctcattga gtaaagaatt gtaagttgcc agacttaatt
     5521 gttccggaac ataaagtgca cggtggttac cgtttgcttt agcagccatt cttgcactga
     5581 cagaatttgc ctgtacagtt atcgcttcac caatcccgcc tcttgcaggg acaaacaggt
     5641 tatgccgttt cttattttcc agattagaca attgttcggc taccacagcc atagtagttc
     5701 ctcccatcac agcgatgata ttctcgcctt ctggaagtag tcggtctagg gcttcgctca
     5761 gcgcttcgcc gaatgcatca gccactttgg tctgctcttc gctgtttcct gaaacaacga
     5821 tacagcgttg gttaccaaaa tattctgcca actgttgttc ggtttgatgc gtacctaaaa
     5881 gctgatccat gaagttttca aggctttgat aaacttcttc gcccttagtt gtcagcgtca
     5941 taccgctttt tgaggtgtcg atcaaattca gatttttcaa aagatctgtt tctgttcgca
     6001 atactcgttc tgtgatcccc atactttccg ataaacttcg acgtccaatc ggctgcatcc
     6061 aatagatatt tcgtaaaatt ttatagcgtt cttgcaacac ttcgataata tctggtgcaa
     6121 cagattcaat catttttatt tcatccagca tagcgatctc cttagttgga cactttacgt
     6181 ccaatgtaga cttaaaacga cccatatacg ataaaaaaag aaattaacta ttcgaatttc
     6241 acatcaataa agggaaatct caacctcacg actgtaagtc taacagtttt gctctcgttt
     6301 ttcaactaaa aagactagaa aaagtgaaat actttttcta gtcttttgac tgattagtta
     6361 tcataacgtt ttctttttga tgaactcggg attcctaata aatcacgata ttttgctact
     6421 gttcgtcttg agatcgctat ctcatctttt ttcagcaatt caaccaattt ctggtcagac
     6481 aacggcttgt ttttgtcttc ttgatcgact aattcctgca gctttttctt cgctgtatct
     6541 gctgaaaggt cttctgtctg ttctgtacta ttcgtaggaa ttcgtgtagt gaaaaatttt
     6601 tttaattcaa atacaccgaa gtctgtttcc aaatatttcc cgttgactgc acgactgacc
     6661 gtggattcat gcacatctat ctcagttgca acttccttta acgtaagagg cttgattgga
     6721 cgttccttgt cgataaagaa agctttttgc cgggaaacaa tgacttgagc aacccgcaaa
     6781 attgtatccc cacgttgtag gatcgttttc ttcaaccatt cgaattcctg tttccgttct
     6841 tttaaataat tttcagtttc tttatctgct tgttgtgaca tttgtttgaa gtaactctct
     6901 tgaaagcgta tatttggctg attttttcgg tttgagataa cttgtacatt tttatcgtcg
     6961 tccactaata cccggacatc aggaataatg tacaattcgc tgctacggtc gaaaatccgg
     7021 ccagggcttg gactcaacgt ttgtaaatag tcgaatatct gctgaacagc atgtagatca
     7081 acagaaaaac gttgtgcgat ttctttccat tttcgctcca ccagttcctc aaaacattct
     7141 tccaacacga tataagctaa ttccggcgca taatcatctc gttctgtttg aagcatgaga
     7201 cattcttgca aactacgtgc acctactcca gctggttcta attgctgaat cagagtcaac
     7261 gcatcgagca tttggatagg cgtagctcca atctcttttc cggcttcttc taaactaatc
     7321 gtcaaaaatc cgttcaaatc gatgtattct acaagataaa gaacgatttt cctcaaaaaa
     7381 gtatctcggt aattcaaatg gacttgttcg atcaatgaat caaataaaga cccttttgta
     7441 tcaggaatct gatttaggta atttgtctct tctccttcat aagaagatga agaagctttt
     7501 atgtaatctg gctgccattc cggctcaaca acttccacca atggattttc cattgcttga
     7561 ttctcaacga atgccaacag ctcctcactg ttatattgta aaacttggat ggactgttgc
     7621 aactgttgcg tcatggctag tttctgtgtc tgctgctgtt tttgtgaaaa attttgctca
     7681 aatttcattt ttttgtccaa tccccttgta attttttatc tgtttagtta caattatccc
     7741 agtgcttgcg tccttagtgt agtggatatc acgtaagatt ccggttcttg agacgggggt
     7801 tcgattccct caggacgcgt tctactgcta ttttagcata atttacgaat agttgcttct
     7861 ttatttttaa gtgaaaactg tccgccaaag aaaattggtg gacagttttt tgttgtacct
     7921 gtatagatat tgttaagcct ttgcaagtaa ggtagttatg tgttcaacta cttattaaaa
     7981 tgtgttattt attaaagata cttgtctcac ttactgaact ggccgatgat cgtttctgcc
     8041 ataatagttc tcgacagccg ttggatgccc taataaatcc ccaactgtcg tgatgcgata
     8101 cccttgctct ttcagataat cgatcacttg aggaacggca cgaatcgttt caggatagat
     8161 atcatggaat aaaataattg ccccatcgta tactgttgct tggatcttct gcaaaatcaa
     8221 atcaggattt cttgtcttcc aatcttctga atcaacagac cattcgatga tcggtcgctg
     8281 gatgatcgtt gctcctacat tcgtgacaga accatagggc ggacgaacaa aagtgggggt
     8341 tttgccagtg acttttttga tctcagtgtc tgctttcgtc acttcctccg tcatcgactg
     8401 ggcagaaaga gtggccagat tctgatgatc gtatgtgtga ttgccaatct cgtgccctgc
     8461 ttcagctgtc tgcttcacga tttcaggatg ctgcgccgta ttttctccta agacgaaaaa
     8521 agtggcatgc acgttttttt cttttaagat tcgcagaagc tgcggtgttg tggtcgctcc
     8581 tggtccatca tcaaagctga ttgcgacgct tttgacagcc ggatctcggc tcgtttttgt
     8641 actgtcttgt gttgattgtg atgactgact ttgtaccttt tccgctgatt cttgaatggc
     8701 ttctttgacg ttagctgttt cagttgattg gcttttaatg gttgattgtt ctgattgttt
     8761 gaaagattgt gacgaatgct ccgaagagtg tgtttgtcct tttacttcgg tgatcaagga
     8821 ggccaccgaa gtaatttcga aaaacaaaag cacggataaa gcaataatac tgataactaa
     8881 ataatttctt ttcactatat ctcttctttc tctttttctc ttcttattat ttacttgtac
     8941 ttacttgaaa attgaaactg ctagtcgcaa ctacttctcg tctaatgatc caaataatct
     9001 tccgatgcca aaatcgtttt tgtcacggac ttaggaatga caaattctgg tgtacccata
     9061 taaccaggag caatttcgta ttgagaaaaa gtcaaaacta attgatgctc tttgttcaaa
     9121 taaaaacttc gtgtaggcgt aacaagtgtt ggtttttcta tcgtcccttc ttgaatatct
     9181 tgctcagtcc aatagtactt agatggatct tccttgactt gttcggccat ctgccgtttg
     9241 acttcttttg tcaaaacaga tagataggtg tcatctttga ataaaagtgg aagtgagagc
     9301 tggacactgt ttttcttgtc gattgtgtcg tatctttttt caacatggct atctgctgct
     9361 gtttgggtga tctgcctttc aatcacgaga aaccggttat cgtctacgat tttctgataa
     9421 tctcccaaaa cttggtaatg atccgtttca aaatttccat attctttttc agctttttca
     9481 aaatctgctt gtccttcgcg aaagtatttt tgatttaatc catgaattgt tttattttct
     9541 ttctcatttt gtgtattgat cttcggtacc tgaatatcga ttttttcaga tcgatcagta
     9601 aagcgttcgc ctaagatcaa ttcaatgact gatcctaaga tgggtaaatc ttctgcaaag
     9661 cttcgaactt gactattaaa aagaaggcta cttgttgtaa tcattacgat agccaaagat
     9721 actccgaacc cttggagacg tctctttctc cgctttgctt ttataaatga ttgctcttcg
     9781 ataataaaac gctggcggat ctcctcttta agccctttgg gaattgcttg ttctttataa
     9841 gttttcttta gtttttttaa attttctttt tgggaataca tggcactctt ctctccttca
     9901 ttctaggatt tgacgtaaag cattcaatga gcggtacatt ttcgttttaa ctgtgttttc
     9961 attcatatcc aagatagtcg caatttcttt caaacgaaat ccttcaaaaa agtagaggat
    10021 cagaatctct ttttccggac tgtctatttt atctaaaatc atatggagct ctgcaacgga
    10081 agtttctaaa ggtaactgtt gggggatatc ttgaatttca aataagtcca caggcgtcct
    10141 tttttgtctg cgccaactat ctaatgccgt gcggatcaat atccgataaa accatgcact
    10201 aaaatgctcg atctcttttt ctttttcaaa atagttcagg gctttatgaa aactatcttg
    10261 catcacatct aaggcctctt ctttatcatg tacgtaattc atcgtgatac ggaacatttt
    10321 ttgataatca gtttcgatga gtccattcag caggtgacgg tatttttcga tctgccgttt
    10381 tttcttatat ccagtaaaaa tcattctcca ctcctttctg cctcacttaa tatgacgtac
    10441 aaggtgcgct aaaagtttca atttttttat tttttatgta tttacttggg atttttatat
    10501 acaaaaaaga aggtgtgaca aaaatcgtgt cacacctcct tattctgata ggctgatcgt
    10561 ctctgtcaca acctctcgta agaaaataat gtttattctt tttcagagtc agaaaattct
    10621 tcctcttcat aatcttcatc atcatcgtct tcgtctatga tacttaaatc ttcttcgata
    10681 tttcctggca agtcttcttc atcatctgtc gggtcatctg ctccgatttc ttgcaagtca
    10741 gaattataag cagcgatttc ttcatcttca tcatcatcgt catcaaacag atcatcgtca
    10801 tcttcttctg tcagatctgt atcttctggg tcatcgtcat tgtaatcgat cgcgtcttca
    10861 tcatcattga taaaggcgtt gactttcttg cgtttacggc gacgtggagt atcttcatcc
    10921 tcttcgtcca ttccatggtt tacttcttca tcgatcgaat cgatagcata ccatgaacgc
    10981 aagccccaac gattatcccc taatgagata aagctgccgt caatattcaa gtcagtataa
    11041 aattgtgcga gtgaatcacg aatttcactg tctgatttcc caagatagtt ttggatctgg
    11101 ttagctaaat cagaaaaatc catgacatcg ccacgttgtt ctaagatcgc gtgtgctact
    11161 tcgatcattg ataattcgct tttgtttgca ccttcaaata cactaatttc caatcaggac
    11221 acgtcctttc acagtctact ccttatcata caaaatcaga cacaaaaaat caaacttttc
    11281 ttttatattt acgctgtaaa atccaaggtc aaataatatt cgccgatttt ttccggtccc
    11341 atgaacagat cataatcgat tcgaaccttc cctgctgtgg gacggtcttt caaactaaca
    11401 tgcagttctt tcgtaaaagt agcaatctgg atcataccgt atggtgttcg ataggatgtt
    11461 tctaaccgtt ctttatagcc aaatttcaaa cgcatccgca tttctcctgc acggatcagc
    11521 tgtacatgac catctggaac taatttgatc gttacaggaa tctcatcgcc cgtctcctcc
    11581 tgaatctctt tataacgtat gtacagcgta tcgccaattg tcaccatttg ccctttcaaa
    11641 tcaaaataaa aatcttgcac ttccccttgc tgttttactt ttgtacgcaa tttgattgaa
    11701 atcggtgttc cttgtgataa ttccattatt cattctcctt tacttctcat agctacattg
    11761 ttcctagttt cttttgtttt gtcaaccaac ttgtccattt ttacagaaaa ccttttttcc
    11821 aaaacaactc tttgatttta gagtataata ttgtagaaaa tatgaattta tacaaaggag
    11881 ccggttgaat gaaccctgcg attcgactag atcagcacat ttatcaaaaa aacgactttt
    11941 ccccttttgc attaacagat atattaacgg aatattctaa agaacaccag caaatctttt
    12001 tacatttctg gcaatatgac tgcacagtca tcttaggtat gaaggatgtt cgaactcctt
    12061 ttctaagtga cgggatccaa acactggaag atgcaggtta cgctccagtg atcagaaatt
    12121 caggtggatt agggatcgta tcagatgaag gaattttgaa tatttctttg attttccccc
    12181 aaagtgacac aaaaaaaata accatagatg acgcttacga gcaaatgctc ctattgacta
    12241 aatacgcttt tccaaaggca ccgatacaag cattcgaaat cacccattct tattgtcctg
    12301 gaacttatga tttaagcatc catggcaaaa aatttgccgg tatcgctcag cgtcggatca
    12361 aaaatgggat ttctgttatg atgtacttaa gtgtcaacgg taatcaggaa aaacgtgggc
    12421 aagtcatgaa gcgattttat caatctgctt taaaagaaga ctttggtaca aatggctatc
    12481 ctgcagtgga tcctgctaca atggcaacac ttgaagaact gcttgaccaa cccctttttg
    12541 taaaagaagt caaagaagca tttgcaaaag cttttgaaaa gctgtattct gcaagtgatt
    12601 tacaggattc taccgactgg ctaaaaaaag aaatccagct ggagcaatgg aacaaccaaa
    12661 tccagagaat ggaacaacgt aataacataa aggagctaca ttatgacaac cccttataaa
    12721 tatcaaatgc tgcctatgga aaaagttttt cgtgatccag tccataacta tatccatgtc
    12781 cagcatcaag taatcttaga tttgatcaat tcgaaagaag tccaacgtct acgacgcatt
    12841 aaacaattag gcacttcttc tttcactttt cacggagcag aacatagccg ttttactcat
    12901 tcattaggcg tttatgagat ttcaagacga atctgcgata tcttttctcg aaatttttca
    12961 aaagaaaaaa taggcaacgg aggctgggat gatcaggaac ggctggtgac tttatgtgcg
    13021 gcactgttgc atgatgtcgg tcatggtcct tactctcata catttgaaca tatcttccat
    13081 acgaatcatg aagccatcac tgtagagatc atcacttctc cagaaacaga agtgtatcag
    13141 attcttaacc gagtagaaga aggttttcct gaaaaggtag ctagtgtgat ccaaaaaact
    13201 taccccaacc cacaagttgt ccaaatgatt tctagtcaga tcgatgcaga tcgaatggac
    13261 tatttgcttc gggatgctta tttcactgga acagaatatg gaacatttga tcttacccga
    13321 atattacgtg tgattcgtcc ttatgaaggc gggatcgctt tttccatgag tggcatgcat
    13381 gcagtggaag attatatcgt tagccgatat caaatgtatg tgcaagtgta cttccatcct
    13441 gtttcccgtg gtatggaagt aattttggag catctgcttc atcgcgcaca cgagttgtat
    13501 caagaagatg ccagcagttt tgaactccat tctcaattac ttctgccatt tcttgacgga
    13561 agctttactt tagaagaata cctcaaactt gatgatgggg tcttgggcac ttactttact
    13621 caatggtctg aatctgctga tcctatttta aatgatttag ctaaacgttt tttgaatcgt
    13681 aaaccactga aatctgctac tttttctggc aaccgggatt caaaattagt ccaagaactc
    13741 actttgttag tagaaaaggt cggatataat cctgtttatt acactgctgt gaattctagc
    13801 tacgatctac cttatgattt ttatcgccca gaacaaggca gacatcgcac acaaatcgag
    13861 attttgcgaa atgacggaac tttgatagaa ttatcacagg ttagtcagct tgttgctgca
    13921 ttagcgggac aagaacaagg agatgagcga tttttctttc caaaagaaat ggttgatccg
    13981 tccttgcgtg atcattatga tttatttgac gaaacttatc aagaatttgc cagccatatc
    14041 cgtaatggcg cattgattga aataaattaa aatatattgg aggaaattat gtctatcaaa
    14101 ctagtcgcta tcgacatcga tggtacttta ttaaatgaga aaagagaagt aacaaaagaa
    14161 gtaaaagaag cgattgccgc tgctgttgca aaaggtgttt cgatcgtttt atgcactggc
    14221 cgtcccttac caggtgtcca ggaacagtta aacgagttga acctttttca agataatgat
    14281 tacgttatta cttataacgg ggcactcgta caacaaacga aatcaggtaa aatcatcgcc
    14341 cgtcacggac tgacacatga agatttccta gagatcgaag taatggcacg ccgtgtcggc
    14401 agtcatctcc attcgatcga tgacaaagcg atctacacgc ctaatcgaga tatcagcgct
    14461 tatacgatcc acgaagcaag tttagtcaag atgccgctaa aatatcgaac acctgaagaa
    14521 atgacaccag acatgaacat cgtcaaaatg atgatgatcg acgaaccaga aattttagat
    14581 gcagcaattg cgcgtttacc gcaaactttc cgtgataaat acacaacggt caaaagtgcg
    14641 ccctattact tcgaagtact aaataaagaa gcaagtaaag gtgcggcagt tgcgaatctc
    14701 gcacagcacc ttggtattga tcaagatgaa atcatggcta tcggagataa cgagaacgac
    14761 ttatccatga ttgaatatgc tggtctagga gtagcaatgg gaaatgccgt ttctcttgtc
    14821 aaagaagcag caaatgtcat cacttcatca aacgacgagc acggtgtagc tgaagcaatc
    14881 aaaaaatatg tactgtaata aataaaaaaa ctgagagaaa gctgatctac tcgctttctt
    14941 tcagttttta tttttttcga tccatctctc gactgcccat cggtggctac cacgtttcaa
    15001 tttcacaagc gcttcttgag ggctcaccca ccaaatttta ttggtctttt cagttggttc
    15061 tcctatacgc ttccaagaat cagcaacaaa gaaatatcct ggattataat aataagttgc
    15121 acgataattc gagtaaaaat actcatcagc ttctcccaga taagaagaaa tttctgccac
    15181 aattcccatt tcttctatca gctcacggac aatcgcttct tctttcgtct cttctccttc
    15241 aatttccccg ccaggaagaa aaaaagcacc atttggagcc tcgattactg caatctgctg
    15301 atctctttct atgacaatat atgctgcata acgggtttga taatcagcaa attgcttttt
    15361 ttcaccaaaa attggtttat ccatgaatag tttccacctt aacagtttta ttttctatcc
    15421 attttacatg agaaatttct catgaacaag cacaaatcaa ctatttcctt acttcttttt
    15481 gttatgattg agtaaaagga aaaggagaga tgaatctatg aaaatggctc acacatgtgt
    15541 tcgagtgaaa gatcttgaag catcaatcga attttatcaa aaggcatttg gttttgaaga
    15601 aagccgccgc cgtgattttc cagaaaacaa atttacactt gtttatttga cacttcctgg
    15661 ggatgactat gaattagagt tgacttacaa ctatgatcat ggtgcgtatg atctaggaga
    15721 cggctatggt catatcgcta tagcagctga tgatctagaa aaattacacg agcaacataa
    15781 agctgctggt cttgagatta ctgacttaaa aggattacct ggcactgcgc cttcttacta
    15841 ctttgtcatt gaccctgatg gttataaaat cgaagtcatc cgaggatagt tagtatgggg
    15901 cattttactc ttgattgaat aaaaaacaaa caccaataat taaaatgaga cgcaaacttt
    15961 tcattaaatt gaaaaagttt gcgtcttttt ttaacaacca ttgtagctat aaggttgcca
    16021 ctctccacca atttattttt aattcatttg aaagaaatca aataaacgag gtacctttag
    16081 aaaacaaaac tgcttttcct cctattatca cacgatcttc ttttaattca cattctagat
    16141 ccccgcccct tgatgacatt tgataagctg acaattttgt tttattcatt ctttctgccc
    16201 aataaggaat aagattagaa tgtgctgatc cacatactgg atcttcattg attgttaatt
    16261 ttggaaagaa ggttctagaa acaaagtctt tttgcacact ttctgctgtc acgatgactc
    16321 ctattcctaa ttcaaaattt ttgatagctg taaaatctgg ctgcaattta gccaccgttt
    16381 tttcatcttc taatacgaaa aataaatcac gtgctaagta ggcttcttta atcttagccc
    16441 caatcgcttc ttcatattca gacaatatcg gcactttttt cggcataata ctaggaaaat
    16501 ccatgtaata ataatcttta attcttgtca caaatagatt accgctttga gtagaaaatt
    16561 taatcgtttc atcaggtatt ttgtaatagt taaataaaac aaatgctgtt gctaatgtcg
    16621 cgtgaccaca aagatcgatt tctcgatctg gcgtaaacca tctaagctca aattcttggt
    16681 ttttcttcac tgtaaatgct gtttcagata aattgttttc aatggcaatt ttttgcatcg
    16741 taccttctgg cagccattct tctagcacat aaaccgctgc tggatttcct ttgaacacct
    16801 catctgcaaa tgcatcaact acgtaataat ctaagttcat tttaaagccc ctttctctaa
    16861 tttgttataa atatattctg cacaacaaag atcttcaata gctagaccaa ctgcgtcgaa
    16921 aatcgtcggc ctcgattctc ctttataaaa tgtttttttc tcagaaacta attcgcctaa
    16981 tgtaccaaca atacaagatt cctctaaatc tccttctgcc atggctataa gcaggtcccc
    17041 gctttctgtt aaggcagctg agtaatcatc tacatagatt tgagaagttt ccatcaacga
    17101 tgtacttatc tctcttgtat caggagtaaa tgtgcccaca gcattgatat gtgcgtcttc
    17161 ccttacccac tctttttgaa gaaatgcctc tttactagag gtcaacgtac aaatgatttc
    17221 cgctggacgt actgcatctt ctactgatat tgcatttata aacgttattt taggatactg
    17281 ttttttagct ttagcgataa aagtatttcg tctttcttct aaaatatcgt aaacaaacac
    17341 tgtagtgatg ggacgaatgg tagaaatcgc agtcaaatgc gacaatgctt gttgaccagc
    17401 tccaattaaa gcaagtgttt ctgcatgcgg atttgctaag taatctgttg ccagcgcaga
    17461 tacagcagct gttcgaatcc aggtgactgc atttgcgttt atcaatgctt tgggtagtcc
    17521 gttttgagca tcaaacaaga aaatctctcc taaatgagaa ggtaaatgat actgatgatt
    17581 atccggaaaa gcggtaatga cttttgtgcc aaaatatctg ttctccccca aataagcagg
    17641 catcatcgca aacatatttt tgccttttcc gtcaggtaaa atttccacca atcgaggatt
    17701 ttggctgatt ttaccacttt cataatcaaa aaaacatttt ttcattactt gaatcgcttc
    17761 ttcaaaacta aaagaagcta ctacttcctc aaaattaata attttcatag acaattccct
    17821 cctcacaaaa gattaacttc taaaatcaat acaatcaatg gtaaaattgt atggtataca
    17881 attttaagga gtggagaaaa tgcctattaa ttcttatgac aattacccgt taacttggcg
    17941 accagacaaa caaaaattga agcgtcctta ttatcgatcg ttgattcaac aattagaaca
    18001 agatatttta aagaataaat tacagaaaaa cactcagtta ccctcccaaa gagagctagc
    18061 tgattattta gatttaaatt ttactaccgt tggcaaggct tataaatatg gaattgagaa
    18121 aggtttgctg tatacgaata ttggaagtgg cacatttatt tctcccaatg tctttgagtc
    18181 catcaccatc tctaccaatg aagtaaccga acatatcatt gattttggtc tggttagttc
    18241 ttttgaagaa tgtaataaat tcgttgtccc gtttattcaa tcaactagta ataacccaaa
    18301 tcttgttggt ttgcttaatt accaagatcc caaaggcaca aattttcaat tgactactgc
    18361 agcaaattgg ttaaaaactc aaggagtcat tccgtcctta gaatctctat ctattgtttc
    18421 cggtgttcaa aatggattgg ctatcacact ttctgcactt ttctctccag gtgatagaat
    18481 agcaacagac cgatatacat acgctaattt cattgaattg gctcagttat atcatttaga
    18541 gatcgttcca attgattttg acgagcaagg aatgcgacct gatatattga ttcaggaatg
    18601 tagaaaaaag aagattcatg gtgtctttct tatgccttct tgtaataatc ctatagggtt
    18661 tcaaatctct cacaaaagac gagagcaatt agccgaagtg attgaaaaag aaggtctatg
    18721 ggttattgaa gatgatatcc attcattttt aacaacttac tatcaacata cgatcattcc
    18781 tcctttccaa aatttattac ctaaccaaac aatctactta gctggaatga caaaatttat
    18841 ttgttctgga ttgcgagttg cttatcttgt agttccagta catgtccaaa gcaagataga
    18901 acaagcaatt tttaatataa atgtgaaaac ttctggatta gatgtggaag tcatcactca
    18961 aatcctccat tcaaatgaag caaataggat cttagaaact aaattaagtc ttacaaaaag
    19021 agccaatcag ctttttgatt ctcttttcaa agtagaaaaa ccaacgaatc gtgtccctta
    19081 ctatcgaatt cttccagttg atcctgagat tgaccctaag ataattgaga atgactttct
    19141 tgctaacggt atccgacttt atcattccag acgctttact acacgtgcgc aaccagatgc
    19201 attcgttcga atttccctat cctctaataa ccttgaaatt ttagcttctg gactaagtat
    19261 cgtaaaagaa aaaataaaaa aatatgaatt ataacctatt gataaataaa ggaatcaaat
    19321 cttattgatt cctttcaata aaaaa
//
LOCUS       DAFEEZ010000055        19109 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000055
VERSION     DAFEEZ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19109
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.057"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(21..251)
                     /locus_tag="LP245_002080"
     CDS             complement(21..251)
                     /locus_tag="LP245_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519979.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="LP245_002081"
     CDS             complement(687..1253)
                     /locus_tag="LP245_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL1519980.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="LP245_002082"
     CDS             complement(1253..2209)
                     /locus_tag="LP245_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBL1519981.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="LP245_002083"
     CDS             complement(2209..2865)
                     /locus_tag="LP245_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBL1519982.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="LP245_002084"
     CDS             3235..5253
                     /locus_tag="LP245_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1519983.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5323..5529
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5680..8094
                     /locus_tag="LP245_002085"
     CDS             5680..8094
                     /locus_tag="LP245_002085"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBL1519984.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="LP245_002086"
     CDS             8442..9995
                     /locus_tag="LP245_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBL1519985.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="LP245_002087"
     CDS             complement(10376..12160)
                     /locus_tag="LP245_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519986.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="LP245_002088"
     CDS             complement(12175..13896)
                     /locus_tag="LP245_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1519987.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="LP245_002089"
     CDS             13996..14757
                     /locus_tag="LP245_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1519988.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQFLLTNTDENNIRTEYYHAWIEMKK"
     gene            15724..15992
                     /locus_tag="LP245_002090"
                     /pseudo
     CDS             15724..15992
                     /locus_tag="LP245_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16664..>19109
                     /locus_tag="LP245_002091"
     CDS             16664..>19109
                     /locus_tag="LP245_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519989.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVETQAPIGYELDATPIEFEIERSQTAVVELTKE
                     NRLTPGGVVLTKIDDQS"
BASE COUNT         6280 a         3393 c         3845 g         5591 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtttctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 ttgcttataa aataattata agtatttaga gatttttctt ctaacattct tcaaacaaga
    15301 aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt gtttttttat
    15361 agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat ttggtaatat
    15421 tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt tattttttgg
    15481 aaaaattcac aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa aaagcagtat
    15541 gactaatata aatactattg tcatttatgc aattttttat ggatagtaat tttagagggg
    15601 aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata
    15661 gcaatacatc ttcaagcttt aaaattcgag agaatcatct tggtagtgga atcaactaca
    15721 acaaaaggat taaaccaatt aatagataga attaccaatg gaaaaataga aaaggtagtt
    15781 attctataca aaagttgttt aattcgcttc ggttatgaac ttagtgaaac cctttgcaat
    15841 atatggtaca gaatatagaa attattgaca ttacagaaaa tgatgaagat ttaatacaga
    15901 ttgtcactat ttgtagatac cttttacaag gaaaccgagc caataaagct aagaagatga
    15961 ttaaggagtt gatggaagac gatacaagtt aagaaagtga aactacgccc aaataaagag
    16021 caaaaagagt aattggacgt ggaaaatgca agaaatgaac catcgattcg gtggacagtt
    16081 tattagtaat gacggtttga gaacatccat gacgagaatg aaggaacatc ctaaatgcgt
    16141 ttagttgaac caagtgccaa ataatatggc caaataagcg atcagttatc gatgaatccc
    16201 aagtattcta aactatatat tcattttgat gctaagcatt gatatatttt tttgggattg
    16261 atgaaggtta accaatacag ggactcactg atgaaattct agagtctgac cttggtatca
    16321 acgatttagt gattgtttct aatggaaaag tataaaagta tataagtaca ttaacaaaat
    16381 aactattagg gttacgctcc agcttgtgca aggcactggc aggaggaatc gtgaaatcat
    16441 aattatggtt aagccacacg gacaactaaa agtcatacaa agctatcgaa tcaatcaaca
    16501 gaagacaatc ggcaatcatt agctttgttt acagcttaca ttgcaacgct tgagttgaac
    16561 cgaaaatacg agggaggtaa cgcagccatt ttgagttggg gaatcttttt agaaaattat
    16621 cgggtacctt gttgtttagt caaaattata agggggagta atagtgagga acaaatttca
    16681 taaactgtta agtatgtttc tagttatgct tattgtgatc aatcaatttg ggaacataac
    16741 ggttctagct gagtctttag cagaacagcc agagcgttcg ctgacgatcg aagttgatca
    16801 agaggaggct gctttgggtg agcagttcca gttgcgagtc agaggaacac cagacctgct
    16861 aaatgcattg gtcattgata agagtgagga tttgattgaa ggggaagtga agcaactcaa
    16921 tgattacgaa cgtctgatta cttattcttc ccagcattca ggtaaatacg aattgaccgc
    16981 aagaagcggt gatattcaat caaatacggt ctcaatagaa atcagtgtac cagaagaaag
    17041 cacaagtgag tcttttaatg taccagaaga aagcacaagt gaatctttta atataccaga
    17101 agaaagctta agtgaatctt ttaatgaagc cagatcatct gagccatcta taacgcagga
    17161 atctcagatt gaaagacaag aggagctctt gaattatgac atcggcatct ctgctgagcg
    17221 ccccactttg ccgagcaggc atacacaaac gttaaaggga tacattcaag gaggcgctgg
    17281 cgatattctt gaagaatatg gggagatggt cgtacgagtt cctagagcat cgattggctt
    17341 aattgagttc attagagtgg aggtcgctga tgattcacct ttaaagccac tggcatttta
    17401 ccaagaaggc acagacgttg tttttccatt tacctttgat tatgaaggat taaatgaagc
    17461 cgctcagtcg tatacattca gtatcacgtt tgaagttgct ttctttcaat caggcggtac
    17521 tgagccaaat aatgactttc aagtgagtct tacttatgct gagcgagcag caaacacgga
    17581 attttcaatt acgcctattc cttcatcaag acccattttt tcgaaattat actatggctc
    17641 tagagaaatc gacagccaag gaaatcttgg gaatctgctg attgacgggc aagacgtgac
    17701 caacagtaat aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt
    17761 ggttaccgat gtactaccgc aaggaacaac tttggcaccg aatccgacta catggagttc
    17821 cactggaaat agagaaccta tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg
    17881 tgaagcaaac gttagaactc attatgtttc cgaggaattt gtggacaaag tatcttttaa
    17941 taaggaaacg aatacacttg ttgtggactt tggtaatcta gcagagggtc aatcgtattt
    18001 tattgaatat gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa gacaagagga
    18061 tgggttttct cggaatcgag cgagtatgac ctacaataat caggtaatga gccgagacta
    18121 ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa
    18181 aaatgttatc aatctcaatg aaaatgaact aacgtatact ctgcatgtct cgatgttttc
    18241 tggaacaaga aatacgcttg ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc
    18301 atttctatca gatattccct ctttcattga tgccgaagtc aataatggaa tagttcgttt
    18361 cagtgcgaat aatacgattg gtggtccgac aagttttacc ctctctttta aggtcaatgt
    18421 agaggcgtat gcggtcggcg atcaaatttt aaactttgca acgcttgtga atagtgacaa
    18481 tcgattgaat acgagtactg taagaacaag gaaaatcgat gggcgtatta aagtaattaa
    18541 aactgatgag aatggccaaa ggctggcagg agcaaaattt gaaattttat caagcgattc
    18601 acaagtgata caagaaggta taacggcaga aaacggagaa tttttaagtg aaccgcttcc
    18661 tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa gggtatcttt tagatgcgac
    18721 ggtacatgat gtttttataa atgaatactc catagaagaa gtgacgttaa ccattgaaaa
    18781 catccttgat acgggtggtg ttgaactaat taaacatgct gaaggcagtg gtgaagtcct
    18841 tcaaggagct gtttttgagt tacagaaccg agaaggagaa acgctacaaa ccggtctaac
    18901 tacaggagaa gatggaaaac tggcaattga cggtttagca ccaggagcat atcagctggt
    18961 agaaactcaa gcgccaatag ggtatgaatt agatgcgaca ccaatcgagt ttgagatcga
    19021 aagaagtcag acagcggtgg tagaattgac gaaagaaaac cgacttacac caggcggtgt
    19081 cgtgttgaca aagatcgatg accaaagcg
//
LOCUS       DAFEEZ010000056        18329 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000056
VERSION     DAFEEZ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18329
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.058"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            270..539
                     /gene="rpsN"
                     /locus_tag="LP245_002092"
     CDS             270..539
                     /gene="rpsN"
                     /locus_tag="LP245_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBL1519990.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            554..733
                     /gene="rpmF"
                     /locus_tag="LP245_002093"
     CDS             554..733
                     /gene="rpmF"
                     /locus_tag="LP245_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBL1519991.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            765..1142
                     /locus_tag="LP245_002094"
     CDS             765..1142
                     /locus_tag="LP245_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1519992.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            1163..1312
                     /gene="rpmG"
                     /locus_tag="LP245_002095"
     CDS             1163..1312
                     /gene="rpmG"
                     /locus_tag="LP245_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL1519993.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            1336..2319
                     /locus_tag="LP245_002096"
     CDS             1336..2319
                     /locus_tag="LP245_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBL1519994.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            2349..2471
                     /locus_tag="LP245_002097"
     CDS             2349..2471
                     /locus_tag="LP245_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBL1519995.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            2489..4012
                     /locus_tag="LP245_002098"
     CDS             2489..4012
                     /locus_tag="LP245_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBL1519996.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIIGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSKHEIAQEMMAH"
     gene            4036..4275
                     /locus_tag="LP245_002099"
     CDS             4036..4275
                     /locus_tag="LP245_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1519997.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(4468..4929)
                     /locus_tag="LP245_002100"
     CDS             complement(4468..4929)
                     /locus_tag="LP245_002100"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1519998.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(5124..5342)
                     /locus_tag="LP245_002101"
     CDS             complement(5124..5342)
                     /locus_tag="LP245_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1519999.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            5460..7076
                     /locus_tag="LP245_002102"
     CDS             5460..7076
                     /locus_tag="LP245_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBL1520000.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(7317..8657)
                     /locus_tag="LP245_002103"
                     /pseudo
     CDS             complement(7317..8657)
                     /locus_tag="LP245_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(8933..9088)
                     /locus_tag="LP245_002104"
     CDS             complement(8933..9088)
                     /locus_tag="LP245_002104"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBL1520001.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(9384..9716)
                     /locus_tag="LP245_002105"
     CDS             complement(9384..9716)
                     /locus_tag="LP245_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1520002.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRLAISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(10230..10421)
                     /locus_tag="LP245_002106"
     CDS             complement(10230..10421)
                     /locus_tag="LP245_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1520003.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(10515..10901)
                     /locus_tag="LP245_002107"
     CDS             complement(10515..10901)
                     /locus_tag="LP245_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL1520004.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            11595..12614
                     /locus_tag="LP245_002108"
                     /pseudo
     CDS             11595..12614
                     /locus_tag="LP245_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
     gene            complement(12691..13449)
                     /gene="istB"
                     /locus_tag="LP245_002109"
     CDS             complement(12691..13449)
                     /gene="istB"
                     /locus_tag="LP245_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBL1520005.1"
                     /translation="MTTNHQKVLTNLDELGLLKMKEYYPHYLDSVRNQTISLTDALYN
                     LTQKQLDYQKEMIDKRAIKLARFPTIKSLEEFDFEFQPSINKHDILQLKSFHFLESST
                     NICFLGNSGVGKTHLATAIGIEACIQGVKTRFILFNDLIEKLTRASQRGTLVRTLKIF
                     TNVPLLIIDEIGYTPISKTQADWFYQLMARRYERASTIITTNIPFSMWAKNFDNTTAS
                     AAILDRLIHHSKVFKITGNSYRLKNYHLDKETIG"
     gene            complement(13465..14691)
                     /gene="istA"
                     /locus_tag="LP245_002110"
     CDS             complement(13465..14691)
                     /gene="istA"
                     /locus_tag="LP245_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBL1520006.1"
                     /translation="MRKDVYEGVRFFMINDIKPNFNELGRQYNCDPRTVKKYYLEGSE
                     NSVKKDKDKPKRPSKLDPFKEIIDQKLELNCSAMAIFKFLKKIGYQGGYTIVKDYCRN
                     KKHTEIKKATLRVETVPGTAAQVDWKEDMTLHDKFGKSYTFNLFLYVLHFSKLKFITL
                     TWDRKQDTLFSCLYEAFNHTGGVPKEIWFDNMKTVVDRARTQYRKVVFNTRFYEFSKD
                     AGFEAIACRSYRPQTKGSVESLAKLVERLKPYDYEFYDAVDLISLVNTLCYDLNYEEI
                     SQSTYQRPVDLWEREEKGKLHPVNEALLTPYFEDNIVRIVTNESMVNFRKSKYSVPTK
                     YIGCEVEIEIDPTEKFIEIFYQGEVVQSHELTGKRLNYKETDMFEILKSDVMKHKDDE
                     EIYEYIQRTLTQYDEL"
     gene            14799..14990
                     /locus_tag="LP245_002111"
                     /pseudo
     CDS             14799..14990
                     /locus_tag="LP245_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            15007..15441
                     /locus_tag="LP245_002112"
     CDS             15007..15441
                     /locus_tag="LP245_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520007.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            16058..>18329
                     /gene="esp"
                     /locus_tag="LP245_002113"
     CDS             16058..>18329
                     /gene="esp"
                     /locus_tag="LP245_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBL1520008.1"
                     /translation="MISKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVKAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTDNWEIRLQLDERLAKYVENIQVDSKKVAGISYRRTF
                     VRINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKNLDEIFQEIGED
                     NLKSDRLMYRIYLVSHQDNDKIVPGIESTGYFITDQDNFYNKLDVSENNPDQFKHGSV
                     STKYEKPNVQTKDGSGSTGANGAIILDHKLTKEKNFSYSVSATGTPWYANYKIDERLV
                     PYVAGIQMHMVQADRVVYDVSFESGTKVADLAIERREGHENYGVGSITNNDLTKLIDF
                     SNASPRPVVIRYVLQLTEPLDEILAEMKTAAQVEGNEPFGEDFIFDSWLSDTNKKLIQ
                     NTYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAG
                     TGHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSNKLIAKDELKVQIVS
                     PGFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTS
                     NVADSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTIQSGKPTFD
                     KPDVPLANDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGETEPITGTIPIKIVYQ
                     DGSVGTTDLAVTVSKDI"
BASE COUNT         6189 a         2810 c         3427 g         5903 t
ORIGIN      
        1 aaaagctact taaaacggta tttgtgtttg attggactaa taaaagtgaa ttcttatttt
       61 tcagagccta aactgcatat tcttttaaat gatttgatta tctctatgta ccgataaatt
      121 cgttttcaaa tagttatcta ttcatatgag ttttatttca tgttatttat tgttgacaag
      181 agcaactctt gttgataaag tatcagtgtc aaaacgtaac gattacgatt tgaggtgtct
      241 aaatcaaaat aaaaggagta taaaggtata tggcaaaaaa gtcgaaaatt gctaaagcaa
      301 agaaacaaat ggcgatgatt gaaaagtatg cagataaacg tcaggaatta aaagccgcag
      361 gagatcgcac cgctctcgct aaattgccaa gagattcaaa tccgaatcgt ctgaggcttc
      421 gtgatcagac ggatggtcgt ccaagagggt atatgcgaaa gttcggtatg tcccgtatta
      481 agtttagaga acttgcccat caagggttga ttcctggagt aaaaaaagca agttggtaaa
      541 aggaggaaat atcatggcag taccagcaag aaaaacatct aaggcgaaga aacggttaag
      601 aagaactcat caaactgtag taaaaccaga aatttcattt gacgaagcga atggtgatta
      661 tagacgtagc catcatgtat ctttaaaagg gtactataat ggaaagaaag taattaaagg
      721 agcttcaaaa tagtttaata tataactttt aggagggaat caaaatggaa attatttacc
      781 cacctttagt tgaagaagga ttaaagtatt atcttgaaac gacccagcaa tcgctagata
      841 aatgcacttt ttatcgttcg atggtagaga gaggaattat tactgaaacg ggtttaccga
      901 cccaacaggc aattgaaaat ggattagtca aagattacta tgaggaccaa ggcttatcat
      961 ttgatgattt tttaagaatc tatccaattt ttgaagagta tgacgaggag ttatttcaat
     1021 gtatcgatgg ttattgggag atacctgttg atatgaaaga aaatttagtt tcacaattgg
     1081 aatctggcga gttaactttt gaagatgcac aacaaattca agcatatctt gaagatcgat
     1141 aagtattgaa ggaggaagat ttatgcgtca aaatattatt ttggaatgtg tcgaaactgg
     1201 agaacgtctg tatctcacca gcaaaaataa acggaataac cctgaacggt tagaattaaa
     1261 aaagtattcg ccaaaattgc gcagacgggc aatttttaaa gaagtgaaat agctaagtgg
     1321 taaaaaggtg acaaaatggg cataccagtt acaatcgttt ctgggttttt aggggctgga
     1381 aaaacaacgc taatcaatca agccttgcaa gtctcaccct accccaggga agaaattatt
     1441 ataattgaaa atgagtttgg tgaagttggg attgatcaca aattattagt tcatagcgag
     1501 gaacgggtgt tacaactaaa taatggatgt atgtgttgca gtcttcgcag tgatttatta
     1561 gcaatattga tttctttact ggaaacaata gaagaacatc aacaaccaat ttcacaaatc
     1621 atcattgaaa ctacaggtat agcagatccc caaccaatca ttcaaacact tttaacagcg
     1681 cctcaactaa gaggaagagt atatatcgat agtttattga ctgttattga tagtgacagt
     1741 tttgaactta ttgaaagaga accacaagcc cttaagcaac ttgtcatggc agatcgcatt
     1801 tttgtgtcta gaaaacaaaa cttgaattta tctgcactaa aaaaattaca gagagaaatc
     1861 aaaagtatta accctttatc cgatattcga atgttcacac atagtgaaac gattcaaaaa
     1921 aaggattttt ataatttgaa aaaatttaat catcccttag tttttgaaag tgattcatca
     1981 gaaaatcact ataatggcaa atactatcat caacaccatc aagtacatga gtttaaatca
     2041 attctcttaa cttcagatca agacataaaa aaagattttt tactccaatg gattgactgg
     2101 ctgattttaa ccaaccaagg gagcctgtat cgttttaaag gattgattgc tttacaagag
     2161 caggatttta tagttgccat gcaagaggta aacgaacagg ttaattttca atacaccact
     2221 cgacaaaaag accaaaccac tattattcta atcggaaaaa tgttggatga agaaaggatc
     2281 aaacagagtt ttgataaatt actggcggaa agcaaataat gataagtagt gattgggggt
     2341 aatttctaat ggagaaaacg gatatatcta gtgcatatcg acgacttaaa agcccgaata
     2401 ttaaaactag aaaaagggca ttaaaaatta tcaaagaaca taaacgaaat aaaatgaaga
     2461 aattagcata attaaggaag gaaaaagaat gaagaaaatc agtgtaggac ttattgggat
     2521 agcagctcta ggattattgg gagcttgctc cagcactaat gatgcaaaag tatcgaatga
     2581 taaagatgga aaattagaaa ttgtaacaac attctatcca atgtatgatt tcaccaaaaa
     2641 catcatcggc gatgaagcga acgtggattt aatggttcca gcgggatcag aacctcatga
     2701 ctatgagccc tcagctaagg atatggcaaa agctcatgat gctgatgttt ttgtatatca
     2761 taacgaaaac atggaatcat gggtaccaaa agctaaagaa agttggaaga aagctgggcc
     2821 taatgtagta gaaggaacaa aagacatgat tttattgcca ggtagtgaag aagaagatca
     2881 tgatcacgga gaagaagatc accatcatga actagatcct catacgtggg tttcacccaa
     2941 aatggcaatt aaggaagttt caaatatcaa ggatcagtta gttaaattgt atccgaaaaa
     3001 agcaaaagta tttgagacaa atgctgaaaa gtatttgact aaactgaaac ggttggatgc
     3061 tgactatacc actagtctta aagaagcgaa acaaaaaagt tttgtgacgc aacacgcagc
     3121 ctttggatat ttagctttgg attatggatt gaaacaagtt cctattgctg gactaagtcc
     3181 tgaagaagag ccatcttctg gtcgattagc tgaattaaaa gagtatgtta aaaaaaataa
     3241 gatcaattat atttactttg aaaagaatgc taatgataaa attgcaaaaa ctttggccaa
     3301 cgaagctggg ataaaattgg aagtactgaa tcctcttgaa agtcttacaa aagaacaaat
     3361 ggataatggt gaagattatg tttcagtaat ggaagacaat ctaaaagcgt tagaaaaaac
     3421 aactatggtt gctggtgaag aggtagttcc agaaaaagaa gcgaaggatg aaaagacagt
     3481 tgctaatggg tactttaaag atgccgatgt gaaggatcgc gaattgagtg attatacagg
     3541 cgaatggcaa tctgtttatc cgttgttaaa agatggaatt ttggatgaag ttttcgatta
     3601 caaagcaaaa atcaataaag acatgacagc tgccgagtac aaagattatt atactactgg
     3661 ctataagaca gatattgata ctatcaacat taaagacaac accattgatt ttgtagtcaa
     3721 cggtgaacat catcaataca catacaaata tgttggatac aaaattttga attatgaaaa
     3781 aggaaaccgt ggtgttcgtt ttaattttga aactgatgat gcaggtgctg gtcgttttaa
     3841 atatattcaa tttagtgatc atggaattgc accaagtaag gcagagcatt tccatatttt
     3901 ctttggtgga gaaagtcaag aaaaactcta taatgaaatg cataattggc ctactttcta
     3961 tccagcttca ttgtctaaac atgaaattgc tcaagaaatg atggctcatt aaaatccaat
     4021 ttttggagga aatacatggt aagaaaagta ttattgtcta tggattccaa gaatattgat
     4081 gcttatcggc gttatcgatt tgcaaagcaa atgagattaa atgggagtac attagctgat
     4141 attgctgcaa ctttacatgt tagtattgac acagttcata gagtattaaa acgggatcct
     4201 gattgttgtt ttatcaaggt caatactgga agaagtagac gtttagcaaa acggcataat
     4261 agcttggcca attaattgat aataccagag tagatcattt ttcccttatt tggatttgat
     4321 ctgcttttta ttatgtcttg aattgtcaaa tcaagcgcaa cactttatca aagaagactt
     4381 cataaggtgt tctccaatct aaacactttc taggtctgtt attcagtttt tcaatcatct
     4441 gatttatcgt tgagttatct accgtagcta tctctttcga ttttggcaag tattctcgaa
     4501 tgagtctatt cgtattttaa tttgttcatt gttgccaagg gcatgaggat ctggaaaata
     4561 aaagggcata ttattcaatg cttctgtaac tgcgaaatga ttggagaatt cttttcctct
     4621 atctggagtg atcgttttga ccgcctcatt tggaatactg cttaaaagtt caatcatttt
     4681 ctcgctcaca taagcggctt tctttctggg gaccttcttt cctgctaaaa ggaagcatga
     4741 ttttctgtct gtcaaagtca ctaaacaagt accaccagtt ttgccagcta caatatcggc
     4801 tttccaatga ccaaaatcac ttctatcatc tgcggatttt ggacggccat ggatcgaatg
     4861 agtaaggcaa atctttccac gagactcgac atgatttttt gtatgtcttg tttttcctcg
     4921 atggtgcaat gaacggatca ggcctttatt gccgtgtgag aggggttctg tatcgaaaag
     4981 atcattgcaa attgcacgtt agatcgtgat aaaactaatt gaaaagtcca tatgttcatg
     5041 cttcaaacga ttcgagattt cctctggcga ccactgaaaa tcgacaaata aatgacgaac
     5101 aattgaccaa actcacggat catttagaat gtgataacgt ccgcattttt ttcttcgata
     5161 agcataattt ttttccgctt tggaaggtga atagtttttt tcttgtttct tctcagttca
     5221 tgtaaaatag taaacgggct atgctgaatg tcgttgccaa ttatactaat agaaaatcct
     5281 tcttcgtgaa gcagaaagat tctttctcgt tcgagtatag taagatgacg atactggctc
     5341 ataattattt tccttctagg agtgttctcg acaaacttat actagttgga tatcgattat
     5401 gactcatttt tatgtgttgc acttaaagtg taaattcaag gtatagaaag aggttcccta
     5461 tgaaaaaaat acctattaca atcttaactg gctatcttgg ttcaggaaaa acgatacttc
     5521 taaatcatat tctgtacggt gatcacggaa aggaaattgc tgtcattgta aatgacatag
     5581 gggaagtaaa tgttgatggg gtattagtcg acaagaaagg ttttaaaaga actggagaaa
     5641 aacttgtttc gatgccgaat ggatgcattt gttgtacatt acgcgaagat ttgattgttg
     5701 aactagatca attagtgcaa ttttctgact tgaatcaaat tgttattgaa gcttcaggaa
     5761 tcagcaaacc aattccaatt attcaagcaa ttatattagc taaaaaccct ttagacattg
     5821 atttgaccca acgattagag attggtgcca ttattatagt agtggatgta aaacgttttt
     5881 gggataattt cgaaacgggt gaaaagattc aggaaagaaa agctgaaggt aatgtagttg
     5941 aagaagaaca ggatattcgt ggcttgttaa ttgatcaatt cgagtgttgt aacatattac
     6001 ttttaaataa tagtgactta gtgtcaacca agacgattta caaaattaac ggtctaattg
     6061 ctaagttaca gtccaatgcc aaaataatta ggacaattaa aggtgaagta gacttatcga
     6121 aaattctaaa tacaaatctt tttaatatag atgagacttc ctattcagtg ggctggttca
     6181 aagagttaga gcttggctat caaaatcata ttcctgaaac agaagaatat ggtatctcaa
     6241 gttttatcta tcgaaatcgg ttactccttg acgcacaaaa atttgcccat cttacggata
     6301 aaaattttcc tggcaatatt acaagagcaa aagggtttct ttggtttgcc caacatagtg
     6361 atttttcgac gatctttgaa acatcgggta gctataaaag tattgaatca ttaaattatt
     6421 gggtagctag tttacctaaa attgagtgtc aaatgattat acaaaaaaat cccgaattga
     6481 aggaagcctg gcatccgttg tttggtgaac gcattaataa actagttttt attggtatga
     6541 agatggatca acaatgtatt aaggaacaac ttgagggttg tttaactgat tctcttaatg
     6601 cagataattt ccgaaaaatt tcaccatttc catggaaaaa gtctaatatg tttagccaga
     6661 tatcgttaat gaaattttta agaaaagctg gtgtcaagat aggcgatgtc ataattattg
     6721 gcattttgat tattacctct tttattccct tatttgtatt ctctatagaa aaggagaatg
     6781 aaacaactga agatgctatc aaatatgcca tcgttcgaat tgatggcaag gaaatggatc
     6841 gcttcgattt ggataagatc aatcataaac tcgtgaatta tcatcctgcg aagggacaat
     6901 ataatattgt tgagattaaa gatggaagaa ttcgagttaa agaagataat agtcctgatc
     6961 aaatcgcggt tagaactgga tggatctcaa aacccggtca aacgagtatt tgtttacccc
     7021 ataagttagt tattagtatt gagaaaaaag aaagcacaga ttactacatt tactaatctg
     7081 gaaatagatg aggaggtttt taataagaaa aagatattat tattaataat agcaggggct
     7141 ttattaagtg tgttaagcgc ttgtggacaa gaaaaagaag cggtgacaac aggcacaagt
     7201 atctttaacg ggacctgcaa tggtttagtt aacagtcggt tagattactt attttggctc
     7261 ttcgtcaatg agtgttggtg aagaaattca atagaataat cgagatactc acacggctag
     7321 acagctatct tgtctagccg tgttgttgtt ctggctttag tcagttgggt agtattctta
     7381 gttttcttaa aatattttcc tcgatataaa aagattcgtt ctcggtagtt ttgaaagttt
     7441 ctaaagccat aggcaattcg ttttagtact ttgatatggt tattcaaaca ttctataggg
     7501 ccgttggaat agggaacgcg caacgctcgt ttgatttctg tttggtattt cttgaaggtc
     7561 gtgaacactg gttggtagtg ctctggcaac tccttgtagt cttcttttag gagcgcgacg
     7621 aattttggaa cagcttgtct tctaatagcg gaaagaaaat cctggtagac ttcgtagcct
     7681 cgctttaagg agtcatcata agataatagc cgatcgacta tctccgcttc tgtcagatga
     7741 tctcgaaatg acggacgcca gtagcgatgc tggcccttca attcccacgc attcttttga
     7801 agtagtctcc agtatttctt taagtgcttc gaccgacgat cccttttttt aaaggtcttc
     7861 attacttgaa ttcggtgatt ggtaaaggcc cgatcgatgt gttggctaat atgaaagcga
     7921 tcggcgacga ttcgggcatt cggaaaacgc tctttcacca atgtgcgata gggtgtatag
     7981 aaatctgaaa ccactagacg tacttgttca cggacttttc tagggtagcg caagaaatag
     8041 ccgcgtaaag gattgagttg ccgattttcc acaatatcaa tcagttgata ggtcttgccg
     8101 tccatcatga caaagctcat ggctcccgag acatttttca ctgatttgaa ttcatcgaaa
     8161 cacaccactt ctggtaacag ctggttcaaa gaaatggttt taggccgaag gctgcgaagt
     8221 attcgaatga cagtggtcgg agaaatgtgc ttcatacgtg cgatcaaaga catagaaaga
     8281 ggttcgctta atagctcaag aatggcttgt ttgactctgc gagcaatgga gcagcgacga
     8341 tcactaactg aatcttctgc taaaaaagtc tttccacagt gtttacattt gaagcgctgt
     8401 ttgttaatcc gcagaatggt cttgtagtta ctgacatcat tcaataagat ggatactttt
     8461 ttccagccct atttaatgat cgtttgttca ttttgatagt ggcgatgaaa gcattcctcc
     8521 ggttgatagg tcaatgtgcc atcaaaagca aaacatgttt cgtcattgat gcgctctttg
     8581 cgaaaggcat cttcatgaaa ggtaagattt aggtctagaa tatctagtaa ctctttggta
     8641 aactctgaat aggacatctt gaaacactac tttgaatggt ttttgtcgac tttattctaa
     8701 aggattttaa ggtgtctgtt tgcgtttatt agaaaaaaga aaaagtattg gcaacagaag
     8761 gcgtcaccaa cactagatat tatagatccc ttattttctt cgcttcaaat tgtcaaggag
     8821 tcatcataaa ttttgtatgg attcttttgt ttgggtagta gtcttctaaa taattttgga
     8881 ttaacacctt catctctatt ttacttttat atttgttgga gtcgattaat tctcatttga
     8941 ttgatcgatg aaacgcttca attactgcat tgtcaacagg agtcccagtt tggctcactg
     9001 aatgtgtgat gtggtggtcg ttcaacagct cttgataaat aaaagaccga tgctggctac
     9061 ctctatcgga atgaattacc gtaggcaatt ctccttaata aatttgtaat ggacggacga
     9121 caatctcttt tttcatgtgt gaatctacca tatagtaacg tagaatacga gttgctaagt
     9181 caatataggt ggacaaatag aggcgaccgt cattacatgg aatgtaagta atatccatca
     9241 cccaaacagc atcaatttgg ttctgttcaa attatcgatt caacattttt ttaccatttc
     9301 tttgattgtt ttttctctac catgagaaga tttgcgtcga tgaaatcctc ttgtgcataa
     9361 attcatttca cgcataagaa cagctacaac acgtttattg atttcgattc cttcatcgta
     9421 aagtttttga gtgatccctg gagatccgta tcgatctttg tgttcgtaga acactcgtct
     9481 tcctctttta gtcgtttatt ttcctgttca agaatgtaga aatctgcttt atcaggtaat
     9541 ctttttcctt gtccagcaaa agcatttttc ccgtatcgac gatattctga aacccatcgg
     9601 gaaattgcta gacgagagat attgtattct tcagcaattt tcttggtagt tacttttttc
     9661 tcaaggatat cctgtgaaat ctttagttta aatttacgat catatgtttt tctcaataga
     9721 gttcattcct tccggtaacg taactgatag tcaagaaaag tgtatcatag cccaacttag
     9781 tatcagggtt tgtcaactaa actgtggaag ttgatagata agagttttta acaaccaaaa
     9841 ttctcttgac tatttttgaa atcagacaaa ttttgattgg acacatagtt gaataaatct
     9901 accgtcgtta cggaaggtaa atcgcatgct tttcaattct agaggagaag tcctcgttga
     9961 agtaccatag cccagttctg gattcgacct cctgcccact tcatacgtaa ataaagtaat
    10021 tttaggagtg agactgtgac aaaagttatt tttaagctaa aaacgaatta aaaaacgttg
    10081 ataattaaaa tcattcgttt tagattctat gaatcattat agaacgctgt aaaatcgata
    10141 ctttataatt ataaagaaga tagtttcaaa tttattgttc gaaatttgaa actatctttt
    10201 tacttatgtc acagactccc ttagttgagt tattctttaa tttcgaattt cgagatagct
    10261 agatatattg caagcataca ttcttgataa caatcttgat catattttcc agttctccag
    10321 gattgcttat gaatcaaaga gctaaatctt ttgagaattg cctcaacagc ttcttcattt
    10381 ccagcctttg ctaaaatgaa atcttctttt aaagaattca taaatctacc ttcttcccat
    10441 ggacttataa tctatttctt tgggaaggag gagaacgagc aaagaagcat acaaaattag
    10501 ttattatgca gatattaaac cagcattttt tgaatttttt tgtaaagtcg atgttttaaa
    10561 tttgtcgcac cctgtcttgt aatccccaga acctttccaa tttctttatc agttttatca
    10621 aagataaatt tttcgataag aaaaatttgt tcaggttctt tcaacaaagg aaggattttt
    10681 gctaatttta tatcttcaac aaggagagtc acatttaaaa cattaatcgg ttgtttaaat
    10741 tttatagtat ctttagtaaa caaatatggt gggagttgat caagttgttc atgtttttga
    10801 atttcttctt gttttttata ataagtatta gcggtgttca aaatgacctt ttcaaagaat
    10861 cgaatcaact gggcatttac gcgttcgtcg ttatctgaca tattgcacac ctcctccatt
    10921 aagatttaaa gggaaaagag gcaaaaaaca cgaaaagaag ctaatgcaat tatgctgcgc
    10981 tgcgaataac ttctataagc tcacatgcat tgataggact gctgatgttt attttcaaaa
    11041 atgttttttt agttgataat ggatagttat ctttatactt agaaaagaaa attcatatat
    11101 cttcttaaat atcaaacatg tccttatggc taagaaaatg tcttgagctt tttacgtata
    11161 ataaatcttt tctaaaacct ccttttggat aatattctta ttcgtgtata gattgtattt
    11221 tttatttctt cccccttcat aattaacaac tagaaaagag ttcgaataga cacgtaattg
    11281 aacgaaaatt tttattggat tcccaaattg gaatatttag aaacgaaaaa ttcctattat
    11341 ctgtatagtg cttagataat aacggatcat aataattatt gtctttgaac tagatatatg
    11401 taaatagtat tcatcatgat gaaaaatgat gagttctcgg tgataaaatg tactttttat
    11461 ggtggaatat acatgaaagc gataagtgga tattttataa tgaagtaagt tagcttattt
    11521 tgacagagga atagtatttt agataacgta taaaatacta tttaatgatg tagaaaggaa
    11581 agagagaaac aaaagtgttt tcagataaag aagtcttatt aaagtctctt catgtttgtt
    11641 taaagttacc tatcgtggtt tttaattccg aattcaatat gataaaagag tatcgctcag
    11701 atagaactac ttattttttt tatgattata aaaagttact aactgataat attaaaaaaa
    11761 ctaaagattt ccatttcttt actggtgatt ttaatgagat gtttcttcta tacatgttta
    11821 aaaccagata ttacttattt ggtccattta gagcaaataa tattgataaa gattttttta
    11881 aactaaaaat gaacaatttg aatgttgcaa tggctgatag agaacgactc tataattcat
    11941 tgcaaaattt gactttgtat tctttaggag acattcgaga tattctgatt ttagttcatt
    12001 atttttttac tggaaaaata gaagatctat tccataaacc gttaattgaa tatacagaaa
    12061 atctaagtaa aattatcgag caaatcaaaa tagataatct gttatcacaa aattacgatc
    12121 cagaaatata tctgtttctt tatgaaaata aaatactgga atatgttaaa aatggagata
    12181 ttcgaaattt agaaaacatg gtttttaatc tgagtaatgg aataattcca agtgttagtg
    12241 gagatacgat tcggtctgaa aaaaattatt ctatcattgt ttttgaaaag ttagcacaaa
    12301 cgtctataac attaggaatg gatataatag aagcgtatca aagtagagat gctttgatac
    12361 aagaaaacga attagctgta tcgttacctg aggtcttaaa agtgagggat tctgggattg
    12421 tttattatac taaggaaatc ggaaaaacta agatagagca tctttctccc ttaatttctt
    12481 ctgtcgttca attcatcggc ttaaatatct ataaaagaat tactgtaaag gaaatagcta
    12541 attatttttc tgtaagtgaa actaaattaa gagaaagctt taagaatgaa atgcatatta
    12601 cgatttataa ttattgtcaa tggcggaata aaaatgctgt tttatggcgg tttaaaaatg
    12661 ttgtttttcg gcggtaataa atgcctgtta ttagccgatc gtttctttat ctaagtggta
    12721 atttttcaat cgataagaat taccagtaat tttaaaaact ttagagtgat ggattaatcg
    12781 atctaaaatt gctgctgaag ctgtagtatt atcaaaattt ttcgcccaca tagaaaatgg
    12841 aatgtttgtt gtaataattg tagaagcgcg ttcatatcga cgtgccatca gttgataaaa
    12901 ccaatcagct tgtgtcttac taatcggcgt ataaccaatt tcatctatga tcagtaaagg
    12961 aacattggta aatattttta gtgttctaac taatgttccc ctctgactcg cacgagtcaa
    13021 tttttctata agatcgttaa aaagaataaa ccttgttttg actccttgaa tgcatgcttc
    13081 aatccctata gctgtagcca agtgagtttt tccaacccca ctattgccaa gaaaacaaat
    13141 attcgtacta ctttctagga agtgaaaact tttgagttgc agaatgtcat gcttattaat
    13201 gctaggctga aattcaaaat caaattcttc caatgattta atagttggga agcgcgcaag
    13261 tttaattgca cgcttatcta tcatttcttt ttgataatcc agttgctttt gcgtaagatt
    13321 atacaatgca tctgtcaaag aaattgtctg attcctcacg gaatcaaggt aatgaggata
    13381 atactctttc atttttaata agcctagctc atctaaattg gttaacactt tttggtgatt
    13441 tgttgtcatt attatttcag ctccttaaag ttcatcatat tgagtcaatg ttcgttgtat
    13501 atactcataa atttcttcat catctttgtg tttcatcacg tctgatttta atatttcaaa
    13561 catatcagtt tctttatagt tcaggcgctt accagttaat tcgtgagatt gtacaacctc
    13621 tccttggtag aatatttcga taaatttttc ggttggatca atttctattt caacttcaca
    13681 accaatatat tttgtaggga cagaatattt tgattttcta aaattgacca ttgattcgtt
    13741 ggtgacaata cgaacaatat tgtcttcaaa atagggagtt aacaacgctt cattaactgg
    13801 atgtagtttt cctttttctt cacgttccca tagatcaaca gggcgctgat aagtggattg
    13861 agaaatttct tcataattca aatcgtaaca gagcgtattc actaaactaa ttaagtcaac
    13921 ggcatcatag aattcataat cataaggctt cagtctctca actagcttag ctaaagattc
    13981 tacggagcct ttagtttgag gtcgataact ccggcacgca atagcttcaa aaccagcatc
    14041 tttactgaac tcatagaaac gagtgttaaa aaccacttta cgatattgtg tacgtgcccg
    14101 atcaaccaca gttttcatat tgtcgaacca tatttctttt gggacacctc cggtgtgatt
    14161 aaatgcttca tacaagcatg aaaataaggt gtcctgcttt cgatcccaag ttaatgtaat
    14221 gaatttcaat ttagaaaaat gtagaacgta cagaaagaga ttgaacgtgt aagatttacc
    14281 aaatttatcg tgtaaggtca tatcttcttt ccaatcgact tgagcagctg ttccaggaac
    14341 tgtttcaaca cgaagtgtcg cctttttaat ttctgtgtgt tttttattgc gacaataatc
    14401 cttaacaata gtatagccac cctgataacc aatttttttc aaaaacttga aaatagccat
    14461 agcggaacaa tttaattcta atttctgatc aattatttcc ttgaaaggat ctaacttgga
    14521 gggacgcttg ggcttatctt tgtctttctt tacagagttt tctgagcctt ccagataata
    14581 ctttttgaca gtacgtgggt cgcaattata ctggcgtccc aattcattga aattaggttt
    14641 aatatcgtta atcataaaaa atcgaactcc ttcgtataca tcttttctca atcaattaac
    14701 ctccattcag attgagttaa gaaaagtgta tagaaaaaaa tgtaggaaaa acgacatttt
    14761 tattccgccg ttttcctaca ttttatagcc gccatttaca ttatatctct aagcgaaaaa
    14821 tttctacggc taaaataatg ttgaaatcaa accatactat cagtgaagtt tctttaggtt
    14881 taggattttc agattcttca cacttttcga gagtattcaa aaagtacgca ggtgtatctc
    14941 ctaagcaata tcaattaggt ttagtggaca atttcaacaa cattagctga gaggttttat
    15001 tttattatga gactatatca tttacgtagt ttggaggagt tgaggaaatt ggattttaac
    15061 aaaaaatttt tttgggaaat ttctgatttg agttgtttcg tagaatctga gcgtctaagt
    15121 aatggtaata atagtgtgtt aaatgaatat gacaaagtag taattaataa agtaaaaagt
    15181 ttatgtgaag aagctagaga atctatcagt catattaatg gtagcaattt taagcaaaca
    15241 ttatttaatc tgattaagct agatgctaaa atatcaagtt atttattctt tttaatacat
    15301 gatgaattta tggattatca aaaattggat cagttaattg aaagagaaag ctgggaagat
    15361 tattacgtgg gtctaacttt ttcagaaaag ttaaacaact acaagttaat agattataag
    15421 tatttgagtg aaagcaatta attattcatg tagagtacta gacactttaa atatggacaa
    15481 ttcaattata aagaaaaaga atcaataatt taatgaggct gtgacaaatg tcattttttg
    15541 tttcgctaaa aacgagtgaa aaaatgttga taactccaat cattcgttta agattctagg
    15601 aatcattcag aaatgctgtg aaaccgatac tttataatta taaagaaggt gatttcaaat
    15661 tccgaagaag gaatttgaag tcaccttttt acttatgtca cagtctcatt cagtaatgcg
    15721 ggataaggct ccttattccg ctatttgaat actctgaagt ttaatctaag aaagagtaat
    15781 attttgaaaa catgcttcat cgcatagaaa tgaacttaat ttcagaaaga atacatacat
    15841 atctttttat atgttttcag ctgctgaatg gttaaaaagc acaaatatcc gaaaaaaaca
    15901 tgaagaaatg tacttttttt gttgtaatgt gcatgaaatt ctttaagtaa attagttaac
    15961 ataagtttaa taagattcct attctgtgaa taatacgtat cagatttatc ttttattctt
    16021 actaggaaaa taactattaa gggagttgat ttgaataatg attagcaaga ataataagag
    16081 agtatttcta gaaaaaacaa agaaacgagt attgaagtac agtatcaaaa aattaagtgt
    16141 tggggttgca tctgttttgg ttggtgttgg tcttgtcttg ggaacaactg aactagttaa
    16201 agcacaagat gaaatttctc caagcacccc acttgaaaca gcgataagct ccgtacaagt
    16261 aggtgacaaa gtagcttcgg ggaatacttt tcaggagaat cctggttata cgaaaaatta
    16321 taacttttcg gatttacaat ttagtcctca agaactaact ggagacacac taaaaggcaa
    16381 tacaattgga tttgaagttt acggaaaaca taatattgct gcttctaccg ataattggga
    16441 aatccgcctc caattggatg agcgattagc caagtacgtt gaaaacattc aagtagattc
    16501 taaaaaggtt gcggggatta gttacagaag aacttttgtc cgaatcaatg attcattagg
    16561 tagacccacg aacatttgga aagttaatta tattcgtgca agcgatggat tatttgctgg
    16621 ggcagaaaca actgatacac aaactgctcc taacggggta attacatttg aaaagaatct
    16681 agatgagatt tttcaagaaa ttggtgaaga taaccttaag agtgatcgtt tgatgtatcg
    16741 aatctatctg gtaagtcatc aagacaatga taaaattgta cctggtatag aaagtactgg
    16801 ttactttata acagatcaag ataatttcta taataagtta gacgtatctg aaaataatcc
    16861 tgatcaattt aaacacggat cggtaagtac caaatacgag aaaccaaatg ttcaaacgaa
    16921 agatggatcg gggtctactg gtgctaatgg cgctataatc ttggatcata agttaacaaa
    16981 agagaaaaat ttctcttact cggtttctgc aacgggaacg ccttggtatg ctaactacaa
    17041 aattgatgaa cgtttagttc cgtatgtagc gggtatacaa atgcatatgg ttcaggctga
    17101 tcgagtagta tatgacgttt catttgaatc aggaacaaaa gtagctgatt tagcaatcga
    17161 gcgacgggaa ggtcatgaaa attatggtgt aggttcaata actaataatg atttgactaa
    17221 acttatcgat ttttctaatg caagtccacg tccagttgtt attcgttatg ttcttcaatt
    17281 gactgaacca ttagatgaaa ttttagcaga aatgaaaaca gctgcacaag ttgaaggaaa
    17341 tgaaccgttt ggtgaagact tcatctttga ttcttggttg tcggatacga ataaaaaatt
    17401 aatccagaac acttatggaa caggttatta ttatttacaa gatattgatg gtgatggaaa
    17461 ccctgacgat aaagaagaga gtggagacac gaatccatat atcgggaaac ctgaattaga
    17521 agaagtatat gatgttgata caacagttaa ggggaaagta ttcatccacg agttagcggg
    17581 aacaggtcac aaagctcaac ttgttgataa agaaggtact gtattagcag aaaaaactat
    17641 tgctccaaat gaaaaagatg gagctccaat ttcggatact gtagaatttg aatttacggg
    17701 tgtggattca aataaattaa ttgcgaaaga tgaattaaaa gttcaaatcg tttctccagg
    17761 ttttgataaa ccagaagaag gttcaaccgt tatcaaggaa tcaccaaaag cggttgataa
    17821 acaaaccgtg gtagttggat ttaaaccaga tgctaaagaa tcaattcgga ataataaaaa
    17881 cttacctgaa gatgcagagt attcatggaa aacagagcct gatacttcta acgttgctga
    17941 tagtacgaaa ggtattgtaa ctgttaaaat cggaaatcga acttttgacg tagatgtaga
    18001 gtttgctgta aaagcttctc aagctatgga aaatgatgca acatacgtac ctataacaac
    18061 aaccccagaa acgacaattc aaagtggtaa acctacattt gataaaccag atgttcctct
    18121 agctaacgat gccttttcaa ttttagatgt ttataataag gacttcggca atgcaagtgt
    18181 tgacgcaaat actggtattg ttacattcac tccagccaaa ggggtaggag aaacggaacc
    18241 tattactgga acaattccta tcaaaattgt ttaccaagat ggttctgtag gtacgaccga
    18301 tttggcagta actgtaagta aagatattt
//
LOCUS       DAFEEZ010000057        17553 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000057
VERSION     DAFEEZ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17553
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.060"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            282..521
                     /locus_tag="LP245_002114"
     CDS             282..521
                     /locus_tag="LP245_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520009.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(883..1143)
                     /locus_tag="LP245_002115"
     CDS             complement(883..1143)
                     /locus_tag="LP245_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520010.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1328..1825)
                     /locus_tag="LP245_002116"
     CDS             complement(1328..1825)
                     /locus_tag="LP245_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBL1520011.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1955..2665)
                     /gene="budA"
                     /locus_tag="LP245_002117"
     CDS             complement(1955..2665)
                     /gene="budA"
                     /locus_tag="LP245_002117"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBL1520012.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="LP245_002118"
     CDS             complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="LP245_002118"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBL1520013.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4547..5209)
                     /locus_tag="LP245_002119"
     CDS             complement(4547..5209)
                     /locus_tag="LP245_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL1520014.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5219..6034)
                     /locus_tag="LP245_002120"
     CDS             complement(5219..6034)
                     /locus_tag="LP245_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL1520015.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6296..6739)
                     /locus_tag="LP245_002121"
     CDS             complement(6296..6739)
                     /locus_tag="LP245_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBL1520016.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(6873..7211)
                     /locus_tag="LP245_002122"
     CDS             complement(6873..7211)
                     /locus_tag="LP245_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1520017.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7199..7576)
                     /locus_tag="LP245_002123"
     CDS             complement(7199..7576)
                     /locus_tag="LP245_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1520018.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            7800..8993
                     /locus_tag="LP245_002124"
     CDS             7800..8993
                     /locus_tag="LP245_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1520019.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9159..9581)
                     /locus_tag="LP245_002125"
     CDS             complement(9159..9581)
                     /locus_tag="LP245_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1520020.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            9976..10170
                     /locus_tag="LP245_002126"
     CDS             9976..10170
                     /locus_tag="LP245_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520021.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            10167..10661
                     /locus_tag="LP245_002127"
     CDS             10167..10661
                     /locus_tag="LP245_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520022.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(10823..11995)
                     /locus_tag="LP245_002128"
     CDS             complement(10823..11995)
                     /locus_tag="LP245_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1520023.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12201..13016)
                     /locus_tag="LP245_002129"
     CDS             complement(12201..13016)
                     /locus_tag="LP245_002129"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL1520024.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(13166..13612)
                     /locus_tag="LP245_002130"
     CDS             complement(13166..13612)
                     /locus_tag="LP245_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBL1520025.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(13609..14613)
                     /locus_tag="LP245_002131"
     CDS             complement(13609..14613)
                     /locus_tag="LP245_002131"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL1520026.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(14653..14982)
                     /locus_tag="LP245_002132"
     CDS             complement(14653..14982)
                     /locus_tag="LP245_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBL1520027.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(15108..17435)
                     /locus_tag="LP245_002133"
     CDS             complement(15108..17435)
                     /locus_tag="LP245_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL1520028.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         5069 a         3482 c         3054 g         5948 t
ORIGIN      
        1 tatcctccta gcaactattt aaatacccaa aaaaattacc tctagataat atcataccta
       61 cgttttcact tataaatttt ttcataaaaa aagcgtttag aggcataatc gttaatacag
      121 atggtaacca atgtatctgg tttgaactgg gatatcaccc tctccatata tgtattacta
      181 agactaatag atactataaa agacttgata gttttgcatt gattttgcct aatactgagc
      241 ataggtgtat gctaaacgat actataagga gtgtgtacat aatgaaaaga attctgttta
      301 tcagtttatc aaatttattg ttacttactg cttgtgggac ttctgcatca aagaacatac
      361 cttcagatac gcaaatttcg aatagtatcg attcaacaat ttctacaaat gagaaaaatt
      421 ctccggtaga aacttccgat ataaaagttt ctacctctgc aaaaaacagg gtaaagaaac
      481 tgtcagcacg tctcctttat ttcaaacaaa ctctgaatta gcttcttcat cttcttcagc
      541 aaataatgat gatagtttcg cgtttactcc taactaaatg caacctttac aaatgcttta
      601 cgataacaag cctgagctaa atgatcctga tatcagtttt gcattttttg aaatgattgg
      661 atcggatgat ctttttaaaa ctactagttt gtctatccga aaataggaca gttctggcag
      721 tataggtttt tatcgagttt ctccaccagg cctcgttaca gagacagatt ctctaggcga
      781 accttttgaa taaatcaaaa atcatgaaca atcactgcca actaaataaa gtgccttcaa
      841 aagcttggtc ttctcgcttt tgaaggcact ttatttaaat ctttatgaaa ctaaagtatg
      901 ttcatatttg ttgctatagt tatatagata ttctgttgtt tccaactcat aaacgtgagt
      961 atattttgcc actacttttc cgcatttttc taatatttca ttgcgatcga cgtcatgata
     1021 ttcgtctacg cagatcacaa cacaattttc taatttactg attacttctc caaccacttt
     1081 ttgtttcaag ccaataggtt ggcaaatata tttttttcct aaaatgatag tttcgttatt
     1141 catatttcat ccatccttaa tgtttttcca ttatttaaaa tgataatacc attaaaatat
     1201 gattatgaaa atcaataaca cttgtgattt tataaaaaaa taaaaaaacc gaaaaacaga
     1261 aatgcccact gtctttccgg ctctttttat tcttgatttc tcttcttttt tgtttcaata
     1321 gacgatttta gttattaata aatgaaaaag catttatatt aaaatttgct aataaaagat
     1381 ctacatattt ttctagaaat gcttgatcga tttcatcata ccctttcgtt actccgcaat
     1441 cgatatctaa aacaccgatt aaattacctt cttttaccat tggcactacg atttctgatt
     1501 gtgcggctga atcgcaggaa atgtaatttg catgggtttt gacatcatca acgatcaatg
     1561 tttcttgttt ttcagctgat tctccacaaa ctccttttcc catcttgata cgtgtgcaag
     1621 aaactcgccc ttggaacggt cctaaaatca attcattacc atcgaataaa taatatcctg
     1681 caaagacagt ctcaggcaaa gtctcattca acaatgcaga tgaatttgct aaatttgcta
     1741 accagttatc ttctgcttct aataatcctt gttgctgtaa taataaaatt tcgtatgcat
     1801 cttttttctg tttttctgtc cacatgataa aaaccgctcc tttttgatct atggagaaga
     1861 ttatagctca gtttttttgt aaacgctagg tttcctcctc aaaaaaacga gatacgtcag
     1921 gttaatcacc ttgaacgcat ctcgctgtct ttttctattc tgcttgttgg atttctgctg
     1981 ctaaatcagc ataatcaatc gtttcgtgaa caaaagtcgg atcatcaact ggaaaatgct
     2041 gtacaaggga cgagatgcgg ctaatctcaa cttttccttc agccacttca aaatccatta
     2101 catgtccgcc aaatgtatgt gtatcatcga taaaatgcaa gtgaaatccc gctgcagcaa
     2161 ctccttggaa taattcaggc gtaaagaacc cgactaatgt tccttggaca ttgctttgtt
     2221 ggaattctgg ttgagactct gaaatttttg ctagtcttct gtaaggtttt tcttgcttcg
     2281 gcatgatacg gatgtgcata tttttgaata atccagttat cttcactgcc aaaaataggt
     2341 tttccccggc ttctcttact aatatgtctt ttttcaattg ttctccatct gcagtttttg
     2401 agacagaaaa actagtatct ggcgtaaaat ctgtaattgc tgcatagggg gtaagttcac
     2461 ttccatctaa ttgggcaact gagccatctg atcttccttg ataagctacg ccatctaaaa
     2521 agatgacttc accatcaagc ccatgcaatg ttcccaatcc cagagttcct ttttctaata
     2581 tatgagcaat cgtttctgtt ccatccatca agccagccat caaagctcct aatgtcccgt
     2641 gctggtataa gattttttca gtcatgtcga cacttcctta atagaattga tctggtaaga
     2701 ttgtttctcc caatttctca ttatcacggt aatcaatcgg aatatcaata attacgggtc
     2761 cttctgtcgc aaatccttct tctaaagctt tttctaattc ctctacactt gtagctcgga
     2821 ttcctttagc gccaaaagct tctgcatatt tcacaaaatc aactggacca aagtctacac
     2881 ctgacgcccg ctgatatttc attttttctt ggaactctac catattgtag tgtccatcat
     2941 tccaaatcaa atgaacgata ttcaattttt tacgtaccgc cgtttctaaa tcctgggcag
     3001 agaataaaaa tcccccatcg ccggaaactg atacgatttg tgtatttgga cgcaccaatg
     3061 cagcagaaat cgcccatggc aatgcaacac caagcgtttg cataccatta ctgaataaca
     3121 aatgacgagg ttcataactt ctaaagtggc gtgccatcca aatataatga ctacctacat
     3181 ctacggtaac agtcatatca tctgttactt ttgactgaag cgtgttaata acttctaaag
     3241 gatgcaagat acctgcttct ccttttgatt gaacaatgtc ccgctccgtt aattctgctt
     3301 gaagagatgc taaatattct tttgcatctt ctgacacttg ttgaggctct aatgaacctg
     3361 tcaataaatc aagagtggct gagatatcac cgatcaattc tctttcaggc tgcataaaag
     3421 gatcgatttc agctggcgct tcatcgatca caatgatccg cgcatctttt tccgcattcc
     3481 agtttcttgc ttcatattcg attggatcat agccaatagc aataactaga tcacttcgtt
     3541 tcaaaagcat atctcctggt tggtttctaa ataaacccac acgaccaaag aaatgcgctt
     3601 ctaattcacg tgagatcact ccagctgctt ggaatgtctc tacaacaggc aatgctgtct
     3661 ttccaactaa ttgcctgatg gctaacgttt ctttttcact tgatcctcgc atacctacta
     3721 atagtaccgg tagttttgct tctctaatgc gttcagctag gtaacggata tcatctgcag
     3781 aagcagaacc taatttagga tcgctcaatg gcttgatgac attcccttgg acaggtgcat
     3841 ccactacatc ttgcgggata ctgataaagc tcgcgccttt ttttgaactc ttagccatac
     3901 gataagcatt ggcaatcact tctgaaattg tttctggatc ttggatttct gcactgtatt
     3961 ttgtgattgg ctggaacagt gctgcattat ccatgctttg atgggtcaac ttcaatagat
     4021 cgcttcgttt tacttgtccg gcaattgcta aaactgggtc accttctgct gtcgctgtta
     4081 ccaaacctgt agctaagtta ctagcaccag gaccacttgt tgcgataact actcctggct
     4141 ctcctgtaat acgtccgatt gcttgtgcca taaatgcagc attttgttcg tgacgagtca
     4201 cgattaattc aggaccttga tcctctaatt cattaaatac accatcgatt tttgcacctg
     4261 gtataccgaa tacataatca acatgatgat taatcaaact ttctactaca gatttcgaac
     4321 cttgtttcat tttttcgtcc attgaacatc gtccttttta tgctttattt ttaattatta
     4381 gttagaaata atcacaaata attgatacag tttctaaacc tgtttcattc aaaagtatag
     4441 cacgttttat ttcatttgtt tagccatatg tttcaaaaaa tgaaaaagaa tgacagtttt
     4501 tacataaaaa ctgtcattct taattgaaag tttcaattta taaagtctac agatccatag
     4561 ttctcatcaa tttacgattg ttgaagtaaa tcaaaccaaa tacgatagaa ggacctagta
     4621 gaatacacca ttggggcttt acgaaaaaga agagaaacaa acttgtcaat agtaaaaaat
     4681 ctagtaaact cacataccat tttttcaacg tatagtagaa cgctatccgt agaacttgat
     4741 ttggtttcga cgctggattt ctcacctgaa aataccagta gttgatgcta aaggaaactg
     4801 ataaacaagc aagtaaaaca aacaacggaa tcaaccattt tccataagaa aaacgtataa
     4861 aaaagaaaca atcaaaaatc attatcacac taactatcca agcaaatagc caataaaaaa
     4921 atccctttag ccaaaattgg cgaaacgtct ttatgaacaa acgtactggt gaaaaacttt
     4981 tttcttttgc taattcttct gtcataccta tcatcacgat gcaacctgga ccaataaaaa
     5041 gtaaagaaaa aataaaggaa aagacattcc ttccatctat cgacaaaagg aacgcagctg
     5101 ctatatacaa gatattgaca caccaaaaac aaaggctact tgccaatgat tgatacaacc
     5161 aataaaagaa ttccatataa acatttttgt caaaacgctg ctctttcata atcacctcct
     5221 attccttcat tcctgatgaa gcgatccctt ctacaaaata tttttgcatc gctaaaaata
     5281 taaaagcaac aggaagaaca gaaacaactg aggcagccat gattaatgcg tactctgcat
     5341 caaatagccc aataaacatt ttcaacccta actggattgt tttattttcc gtagaagaca
     5401 aataaatgaa tggccccata taatcgttcc atgtattaac gaatgtgatg atcgtcaaac
     5461 tggcaatcgc cggttttgta agaggtaaaa tgatcttgcg atagattccc cactctgata
     5521 agccatcgat ccgcgcactc tcacataaag aatctgggat actactgtag tattgcttca
     5581 acaagaacac accaaaagca ttgaacgctt gtaatagcac caacgaccac aacgtatatg
     5641 ttaaacccac ttttctcatc ataatgaact gcgggatcat ataagactgc caagggacag
     5701 caatcgtgcc gatatatgct aaaaataaaa tatcgcgccc tttaaaattt agtttagaaa
     5761 acccgtaagc agcaaaacta gaagtaaaca actgaatcaa cgtgatcaca acgcttaaaa
     5821 aagctgtatt cttaaaaaat gtcactaaag gaatacgaga ccaaataacc agataattct
     5881 ctaaatgcca agttttaggg atccattgaa tcggaatcgt gaacacttca ttatttgctt
     5941 tgaatgaagc agaaaccatc cataaaaaag gaatgatcgt caataaagct aatacaatca
     6001 gcagaatcat acccaaccat tgaataaagg gcatgttttt tgaacgaatt tttgcttttt
     6061 ttctttcatt tcgaacacct ccaaagttat aatcttcatt tctttgtaat gattacaatc
     6121 cagaacaacg gttattatag ctgattcatt tccgttcttc ttatgtttgt aagcgcttat
     6181 ttaacaagtt atgtaaatct ctttattttt tttgatttaa aaatgaaaaa atacaaaagc
     6241 aagactgtca tacgtctcgc ttttgtattg aaatttcttc gattagagat acttattact
     6301 gttcaaaagc ttctttgaaa cggtgaatca attcattgac tacaggtgat aaaatccgat
     6361 tctttttcca gactagcatg cagttcgttt caatcattgg gtcaagcgga acgaatgtca
     6421 ctcgctttga aagatgactt acagcacctt ctatgactaa agcagcacct acctgattct
     6481 caattagcgc aaatacattg aaaatcaaat tgtacgttcc tgtgatcagc aactgctcct
     6541 tttttatgcc taaccagtca gcaaacattc gctgtatttc tggacgcttt gagatcaaaa
     6601 gaggtacatt cgcaaagtct tcttttgtta tcacgtcttt ttttgctaaa acagaatttt
     6661 ctaaaatgag caatccccat ttttcctttc ttggtaacaa aatcgtttcg tatttctctg
     6721 tatctactgg atctagcaaa atcgctaaat ctaacaggct tttttctagt cactccgtga
     6781 tatcatcact tgttccgctg tggatatgaa attgaacgct gggataatca cggatcaact
     6841 tttctagtaa tagtgccaat gtattcgaat tatcagcttc cacacagccg atcgtaaatc
     6901 ggccgctgaa taattgtttt tttctgttct cgaattcttg agtggtttga ttcgttaaat
     6961 ctaaaatttc ttctgctcgg cttttttaga aaataacctg cttctgtcaa gatcattttg
     7021 cggttttcgc gtacaaacag ttctgttcct agttcctctt ctaactcctt cagttgtcgg
     7081 cttaaggttg gttgtgtaag atgtagaact tctgcggctt gagagattgt tccttcttct
     7141 gcaattgtcc aaaaatattt tagtaagcgt aactccatag cgatgctcct tgattttttt
     7201 acttgataca ttccatttta tttctagata acacacgatc atatttcttg atttttcctt
     7261 gtaaacgttc caaacactct tgcatttcag caatttcttt cgtcaaaagt tcactttctt
     7321 caatcaaaag cttacgccgc tcaaatacag ttgcttctcc ttcgctagat aggcgaatat
     7381 attcaatcaa agactcgatc gataatccgg catttcgcat acagatcgta aagtcgaccc
     7441 attttaggtc ttcttctgta taatcacgga ttccgccttt tgtccgatta actggtggaa
     7501 tcaacccgat tcgttcataa tagcgcaatg tatcggccga aatgcccttt tcttcactga
     7561 cttgtttgat attcatctga tcactctttc tcttaatttc ttgccacttt acttatgtat
     7621 tttatttatt ctacaacttt aagtgtactc caagtcaata ctcatttcta ttaaaactaa
     7681 gctggattat ctatatcggt tgtttgtgta ttatttcaaa taaaaaagtc ttgttttttt
     7741 attctttttt ggatatactt ttaacaattt agggaaattt taggaaaagg ggtataaaaa
     7801 tgacaacgta tcagcgaaag gtattattat cgacatcggc gggaattgct ttagagaata
     7861 tggatattat gtttttagct ttttcattat cttcaatgat tacttctttt catattagtg
     7921 gtacgcaagc gggtttcatt tcaacgatca ctaatttggg gatgctcatt ggaggtattt
     7981 tttttggcat catagctgat aaatatggac gtgtgaaagt attttctcaa acggtccttc
     8041 tgttttcgat tgcttcttta ttgatgtatt ttgcttcaaa catctacttg gtttatctct
     8101 ttcgctttat cgcaggtgta ggagcgggag gagaatacgg ggcgtgtatg tccttgattt
     8161 ccgaaagttt ttcaaaaaaa caaattggac gagcttcttc ggttgctggt attggtgcgc
     8221 aggtcggtgc ggctttggct gcgattttag ctgctgtgat cattccaacg tttggttgga
     8281 agatgttgta tgtcgtaggt gtactgccgg tgttgatggt cttgttcatt cgtcgcggct
     8341 tgactgaacc aaaggaattc aaatctgtac aatctgccga aaagaaaacc aaacttagca
     8401 gactgtttga atcaaaacat cttgcttggc aaacatgtgg ccttagtatc atggtaactg
     8461 tccaaattgc cggctatttt gggttaatga attggctgcc ttcaattatg caaaatcgat
     8521 tagggctttc ggtttctggg tcttcattgt ggatggtcag tactatttta ggcatgtctt
     8581 tggggatgat gacttttggc ataatcatgg ataaattggg gcctaaacta gccttttctt
     8641 tgtttttaat ttgttcatcc ttatctgtct atctacttgt gttagcccat agccagtgga
     8701 gtttggtagc agccgctgtg atagtcggct actttatcaa tggcatgtat ggtggatatg
     8761 gcgcagtgat tagtagtttg tatccaacag aaatccgcgc gacggcgaat aatttcatta
     8821 tgaaccttgg acgagctgtt ggtggttttt cttctatcgt catcggtttc ttgatggatc
     8881 attatagttt aactgccgta atcttgtttt tgagcggtat ttacctagtc agtctgctgg
     8941 tcttgacaac tcttactggt gttacagcat taagggaaag cttgcagcat tgatagttga
     9001 gtctgtaaat gacaagaaag aggtgtggca aaagcttgca tctgcggtaa taagaccagc
     9061 caaatcaaaa acatgagaca ctgtttccgt ttggctggtc gtattacttg atgcagggca
     9121 gctttttcaa ctgctaattt ccttctatct ggcggcgact attctttgac gtccgtcatt
     9181 tcaaagtact ttactaataa cttagcataa cgaaaaactg tggatacact cgtatattga
     9241 gcgtctgcat aatcttccaa atttttctca ggatgttgat acatgaattc aatcaaatga
     9301 taattatatg attttctgta gaaatgaaga taaataatgt agattgggaa gttctcctgc
     9361 ttttccatag aaaagcgccg attattctca ttcttcaaaa tgaccttatc aggatatttt
     9421 tggaacaatt cttctaaatc tgttagataa ttcaagatag acttacttga taccttcaat
     9481 tcgttttgta gttcttctat tgaacaccaa cgttctgttt caagcagtaa atgaatcatt
     9541 ttaattttct tttgagaaac ttttgttaaa aaagtctgca tattttctcc tcctgtatct
     9601 actttactat actacataca agaaaaaaaa cggatacaaa tatcatattg tcacaccgtc
     9661 aatagtgcat aaacctgtta ttatttctct ttttttccta agtattctat tgatatgaat
     9721 catttaatcg tttattatat aaatgtcaat aatctaataa taaaataacg tacatatttt
     9781 attattgcat acttaataac agaactatag caaaaaatcc cgtgtatcaa cacgggatta
     9841 gattaagttt cctcaatcac tattcataac acaattatta taacaagtaa gtaaacaatt
     9901 gaaaaggaca tttattgaaa acggttgttt tttacttaag gaggaaattt agcgaaaaaa
     9961 ttagttgcat tgtttttggt cgcaggaagt ttgttgagtg ggtgtggtgc tactacgtct
    10021 actactcaaa gcacaagttc agatcaggct tccagcagca gtaccacgat ctccgaaagt
    10081 acggcagatt catcgaaaga acaagaacaa attgaaaaga aaaaagaaga gaaacaaaaa
    10141 gcggaaaaag ctgcactaga aaaaaagtga cagaagcgga atctgctttg tcacaagctg
    10201 aagcaaatcc tacaaaagaa aactatgcaa ctgcttcagc agctatccaa gcgctacctg
    10261 aaaacaaaca agagttgaca agccgtcttg ctgcaattga ttccacaatc aaagcaaaag
    10321 aagcagaaga agaacggaaa aagcaagaag aaattgcacg acaacaagca gaacaagcgc
    10381 aacaagaagc aatcgcacag caacaagcag aacaggcgag gcaagaagca atcgcacagc
    10441 aacaagcaga acaggcgcga cagcaatcag cagctgaaca ggcctctcag caggcacaag
    10501 ccgcagctcc tgagcaaaat aatgaacaaa ctgtctatgt cacaccgacc ggttcaaaat
    10561 accatacaca taaatgtgga aatggtacgt atacccctgc cactttaagc gaagctcaag
    10621 ctcgtggttt aaccccttgc tccaaatgtt atggaaacta attcaaaagt tatactataa
    10681 taataaaatt cttctgaaac ataaaaaaat agaagatggc gttccagata gtaaaccaaa
    10741 aataacagtt tacacgtcca tttcgtcagc ttctctcttt tttcatttag tctgttccct
    10801 ctgctttttt ggacatcttc attcattctt tctcaatcaa atagtacacc tctttttctt
    10861 ttcgcagttt atatcttcct tttttcaatt tcattgaaaa ctgtttcgaa tgtttatgtt
    10921 ttacatggat tttaagcagg agctcctcat gttgcaagcg atagttcctg ccttttaaat
    10981 cagaaaatct cactagtccg tattcatcag aagctttcac aaatggaact ttttctctag
    11041 taatatagtg tttgccgttg agcgttttta cagaaaagac cattccttcg attggtcgtc
    11101 cgtttgtgtt ctttacataa aaagataaag gatagtttcg cttagcgatg gccaaagaat
    11161 ctaaataagc gatgagtagc caaactaagc cgattgatcc aagtagtata ccgataaacc
    11221 aaataaaaaa tttccatttt ttccattgat caattccttg gatcgctttt tttgcctctt
    11281 ttgcttgata aggaatacga tgccccgtca caagcagtcg atgtgtattg accatataag
    11341 gagtacaggt aagcaaagtc acgagatctc tgcctttttg gatacccaaa gaatctactt
    11401 catcaggtaa gaccacttgg attttttcta cttgatacgc caatgtcttt ccattgatct
    11461 ggatgaaaaa ctggtctcct tttttcaact taggcaaatc tgtaaataat tttgcttctg
    11521 ggagtccacg atgcccagaa agaacggcat gggtgttttt cccgccagtc ggataagaac
    11581 tttcttccaa taatgacgtt cctttttgca aaaatatttc cgttgtctga tcgaatatag
    11641 gtaagctgac attgattttt gggatttcga tgactccaag catatgttcc ataaaaaagg
    11701 cattactagg taaatctttt aatgcttttg catcaactgc ttggttgaaa ctgcctatcc
    11761 ctggtgatac gttttgctct gccaactgtt ggtttttctt tgtcattttt tcctgctgtt
    11821 tttttatttc ctctgaattc ttattcgatg cttgcttttg ataatggatg atcatttgct
    11881 gggcaagaaa atcattcagt gaatcttcta caaaaggata agaaaagatc ccgatcccaa
    11941 cgactaaaat gattgccatg aagatgtcca gtattcttat tctgctttta ttcatcatgt
    12001 ccacctattt tctaatatgt atatgaagag gttgtgaaat cagcgccttg acctgagtat
    12061 tagcgaagca aacggcaaaa tagttcctcc tattttgccg tttgttgagc gaataccaag
    12121 agaccgacca cttgtcacaa cctttctccc catttgaatc actatcgttt atttatcgta
    12181 tgatttttgt ttccaatagt ttaagcttct gtttcttgat ggcgtttttt gaaatagatc
    12241 actgctcctc caactaaagc agtacctacc aagatgaata cgatgatccc cataccacca
    12301 gttgaaggca agattccttt aggttggtta tcgatcgttg tttcatcaga agttgttgga
    12361 tcatcatcta ctgtaaattc agtgtacgca gcttcattct taggtaatgc gtagccttct
    12421 ggtgcttttg tttcttgaag gcagtatgcc ccttgtttca gcccttcgat tgaaaatttc
    12481 ccttctgaat cagaaatcaa tttcacttct tcccagtcag aacctgtgac ttcatctgac
    12541 caagcatatg ggtattctcc tgaggcaagg tttgctattt ttttcattaa tttaacagtt
    12601 ggatcttttg ctcttagaat agaaaattct gcatcggcta atttttcttg cgtgttcaca
    12661 tcttgtttga tgaagtggaa atcaccgtag ttttggacat tttctacagt aatcgtgtta
    12721 tccgtagttg tattttcccg attgactaca ccgtttggat tcccaagatt ggcttcatct
    12781 gcgccatgga tgataccggt tgtttgttgc aattttccgt tttttactat aaaagtagtt
    12841 tctttttgtg gattggttaa ttgataacca tctggtgctt ttgtttcaac taaagtataa
    12901 ttgccgtcta ttaatccatt gacactgatg gatccttcag tatcagttgt gaatgtcaac
    12961 gctgactcag caggatcata gagagcgaca ccagtgtttt catcaaaacc ggtcacgaat
    13021 tgattctctg aatttttgat ctggaattgc gcccctgcta acttatctac ccctgaaaag
    13081 ttcccagctt tctggatttt gatattgctt tctttgatga catttttagc atataggtga
    13141 atcgtgtcta aaggtttgtc agggtctagg gtaagcttaa cacgatattt ggcgacgttt
    13201 cgacaccggg ctttggtgtt tctacaaaga cgtatacagc atctttccca tcagatttac
    13261 ctggaagagt caggttagct aatccttcac cagaagtcgt tacacttgcg aagggtgtag
    13321 cgtctgctgg aactgctgtg tctttacttg gatagtacgt agcagtgatg tcatatacgt
    13381 tgaattcaac gccgttcaac ggttcgctat tcggaaatgt caattccgtt ccgttgttta
    13441 tttgattttc tggtgctgaa gtgaatttca atttatgcaa attaaccgta acattttctg
    13501 gtgtaggtga tacggctgca gaaacctctg cagttcctag gccgagaacg aaaggaagca
    13561 gcatgatagc agttcctaaa aacgtccata tttttgtttt gatgtttttc attttatttc
    13621 cctcctattg tttccttttt gttgtttttt ataaaaccaa gctgtccctg ttgaaaggac
    13681 tagcaataac cctaaaattg agaaacctcc aagcatctct tcgcttgttt ttggaaagct
    13741 tcctccattt ttttcatttg atggaccatt tgtctgcatc tgaactggcg tttttccatt
    13801 attcgtcgga tttgcttttg gttcgttgat gatttccaat ggtataggat gaagcggatc
    13861 ataactgcct ttttcaactt caaagagaat ggttgattga ctcaatatat atcctttagg
    13921 cggtttaatc tccactagtt cgtaacttcc aaaagacaat ccatggacag aaaatgttcc
    13981 atctttactg gaagtaaaaa tcgttgctct tgaatcatct ttggctaccc aatgatttat
    14041 cccgttttct tgcgctaagt attggtcatt ttttttgact agaaattgag catctgctag
    14101 tttttgtttc gtttgccgat ccactttgac aaattgtttg cctcctgttt ggatggcaag
    14161 atgtgtttct actgtttgat tgtcagtcgt caaacgtaca tcgttatcaa atgtcgtttt
    14221 ttcactgttt tctttcaatg tcatttggta acggatcgtt aatttttttc cagcaaacga
    14281 actaagatct tttccagaat ctgataagac aaaaccatgt tttatttttt gtgtgtgaaa
    14341 tgtatgaatc ttgtctccac caatcaaaaa atcgatcgtt tctggttcta gccataactg
    14401 aggatcagct gtatctttga tcgtataggt tcctatctcg ttgatgttct caggaattgt
    14461 tacggtgatg agataaggga ctttatcccc atctgcaaaa tctgtctgct tattctctac
    14521 tgtttttgtt aatgtgagtg cagcaggtat tttttgttcg ctctttggat acaagtggat
    14581 ggtcgtcaat ttatgattag atgaatctgt cacaggaagc acaacgacaa atggtgctga
    14641 tttttctttt acttaatctg aagtctttat ttccgtaaat cggtaaacag cgtcacgacc
    14701 ttgctcatct ttgtccgatg cactaaaaga agcaatgccc tcttcctcgt ctactgtttt
    14761 tgtcacattt tctgccagta ttttttcact atcacttttt tgtgctagtt ttctttgtgc
    14821 gtcttccaca ctacttcctt ctgaccgcag cttgtaaaat tcatccgaga catcatatat
    14881 agcgaaagta acgccgttca acccttttac tccttgaaag ttatccggga tatttattcc
    14941 gtcgttttga ctgatacttg gcatcttatc gctttcgaac attcgattat gcaaagtaaa
    15001 tgtaataggt gattctctag ctgacacagt cggagaacct ataaaaaaga ccagtaggat
    15061 aaaaaagaga acagcaaata tatccacacg tacatttttt gtttttttca tcgctgttca
    15121 cctgcttttt tcttacgatg gataaaataa aagaagccag aaaaaataaa gatcagtcct
    15181 aaaaagacaa agggcagtag acctatccca cctgtcgaag gaagcaagag agtcggattg
    15241 atcgtcaact tagcggtatc tgttgcgata atcgtataat tattgtttac acttccttcg
    15301 cctaaactaa tcgttactat ttgtgatcca atatctgtcc ggctgttaac tgttagggta
    15361 taatccaatg attcgcctaa gacaacaccg gtaacgtgga gatttccaac cgaaatcgag
    15421 tgactttggg catcataatt aaaggcagcg tcatcgacag taatcactgc gttagcttta
    15481 tagatggtat aagttcctga tgtgttggct atatcagtaa atgacaactt gggatttgct
    15541 gctttgactt tgtctattcc gctattcgtt agtttaattg tatagctgcc agcattaacc
    15601 atattttttg ctgattgtgc atctgctgtg taatccatac tgctaagtgc cacttgtact
    15661 ggagtaagcg aactagtgac accctctgct agcttgacat ggattgacgg gacacctgct
    15721 tttccatcat atgtcttact gccactgagc tctaccgcac cgctgatttg cttaatcgta
    15781 tagacatcag atgtctgcac gatagtaaat aaatagtttg ttctggcagc tagtttagct
    15841 agtccgcttt ttgtcaattg ccaagacgta taggttccaa tttcagtagg cgcagttact
    15901 tcaactccct tttcattcat cgctttgaaa tcagttggat tccatgtgat ttgatcaata
    15961 ctgagatcat tgtttaaaag ggatgttgat tctgttttat cattaaaggc atatttaacg
    16021 atcggtacaa cagaaagacc atcatagtac ttactgccat ttgcattgat tgatactgtt
    16081 gcatttgtct tataatatag gatgacttca gaaatctgtt ttccatttgc gtcctttacg
    16141 attacatttc catttgtatc taaactagct aaaacactca ttgctgattg gttctttgtt
    16201 tctatcgctg aaacagctgt aaaggtatat ccgttgatag taggcgtatt agtcgtcagg
    16261 tcttgtgcag cacttccgta agtaagattc attattttag aaggagcaat catctgtcca
    16321 aaatagtctt gatacttaat agtgattggt gtttgtttgc ctgtataggt caccgtatcg
    16381 acgttacttt ctagggctgt gaaagaaccg tttgtttgtg caaaagaata gcccgttact
    16441 gctgttggag tgataaccac tttgtcaccc acatggattc cagataatgt agtcccgtac
    16501 gttccgattt ttgctgctcc accattgact gtataagaaa aagttcctgt ccgattcgca
    16561 ttgacctgaa ccgttgctgc ttgataggtt ggaaaatttg aaacatttcc cttaccatca
    16621 acgatctgcc catttttgat cgagtacccc gtgaatggaa tatcatttgc taactgtata
    16681 ccgattgaaa aagtactcat acctcctccg gcaggaagcc ctccccatgt tgagggtgta
    16741 aaagaataac ttttatccgc attgggtgta actgaatcga tcgtatttcc agcggtagcc
    16801 acccccatat agatactttt tgggaatgtg atagtagtac catttactgt ggagccaata
    16861 aacagattat ggatatctgg acggttatca ataaaagcga ttgctttggt tacgccttgt
    16921 aacgcagttt tatccgcact catcgatccg ttaaccgcaa caatgactcc atctttggca
    16981 tatatcactg tatatccatc tggtatggta tgtccgttga aattcgcagt ggccgcaaca
    17041 gtactaaatg tctggcttct acctgtttct gaataagctt tctcccctgc tgcttttgct
    17101 gctgtgattt ctttttctgt cggatcaatc agttgagtcg aggatgtggt tgaggttgtc
    17161 tcgttgttgc tagactgatt ggtgctttct atggactgta tttcagaata gggtggacta
    17221 tttgtctcct ctgtcgtttg gttagcaaaa tttgacgttt ctgtataaac gtttacataa
    17281 atacttgata agctccctaa gaaagtaaaa atcaagatga tcgaaatcat aatgggatgt
    17341 aagtattttc ttttagatac agctttgagt ctagaaacaa aatgtttttg acatatacgt
    17401 tggattttat tttgagtttt cttaatcatt ttcatccctc ctctcaataa aaaatcatca
    17461 aataatcctt tacacgttat tctaaattta atttttatta ttttattgat gtatagaaag
    17521 tttggggctt tttttctctt tttattctaa ggt
//
LOCUS       DAFEEZ010000058        17180 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000058
VERSION     DAFEEZ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17180
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.061"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(20..1039)
                     /locus_tag="LP245_002134"
     CDS             complement(20..1039)
                     /locus_tag="LP245_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1520029.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(1061..2068)
                     /locus_tag="LP245_002135"
     CDS             complement(1061..2068)
                     /locus_tag="LP245_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL1520030.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(2061..2726)
                     /gene="pgmB"
                     /locus_tag="LP245_002136"
     CDS             complement(2061..2726)
                     /gene="pgmB"
                     /locus_tag="LP245_002136"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBL1520031.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(2719..5013)
                     /locus_tag="LP245_002137"
     CDS             complement(2719..5013)
                     /locus_tag="LP245_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBL1520032.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5273..7438
                     /locus_tag="LP245_002138"
     CDS             5273..7438
                     /locus_tag="LP245_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1520033.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            7742..8575
                     /locus_tag="LP245_002139"
     CDS             7742..8575
                     /locus_tag="LP245_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBL1520034.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(8677..10377)
                     /locus_tag="LP245_002140"
     CDS             complement(8677..10377)
                     /locus_tag="LP245_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520035.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            10884..12044
                     /locus_tag="LP245_002141"
     CDS             10884..12044
                     /locus_tag="LP245_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL1520036.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            12060..12503
                     /locus_tag="LP245_002142"
     CDS             12060..12503
                     /locus_tag="LP245_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1520037.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(12986..13516)
                     /locus_tag="LP245_002143"
     CDS             complement(12986..13516)
                     /locus_tag="LP245_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBL1520038.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            13621..14172
                     /locus_tag="LP245_002144"
     CDS             13621..14172
                     /locus_tag="LP245_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1520039.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(14325..14798)
                     /locus_tag="LP245_002145"
     CDS             complement(14325..14798)
                     /locus_tag="LP245_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL1520040.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            14936..16408
                     /locus_tag="LP245_002146"
     CDS             14936..16408
                     /locus_tag="LP245_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL1520041.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            16405..17115
                     /locus_tag="LP245_002147"
     CDS             16405..17115
                     /locus_tag="LP245_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBL1520042.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
BASE COUNT         5339 a         3092 c         3534 g         5215 t
ORIGIN      
        1 tatttagtga gtcagctatt tagtatgggt tttctaaagg aacgactgtc tctcttttga
       61 tcaagcgatg agggatgacc aaacgtacgc cactgctcaa ttcttcatgg atcaattcgc
      121 gcagcttttg catagcgaca cgtcctaatt cggagatatc gatatcgata cttgtaaggt
      181 aagggtgtgt taatgttgag aagatcgagt tgttgaagct aatgacggag agtgtctctg
      241 gaatgacata gccatacatt tgcgccaact gcatcgtgcg aagggcgaag atatcgtcaa
      301 tgaccaccaa tgctgtggct tcgttttctt tcaacgtttt ctcaaaggac agataatcct
      361 ccggatgctc tagtactaca ctggataacg caggaagacc agccatcatc attgcttttt
      421 gataaccgaa atatcgttcg aaatacaaac tttcatgagt cgtgtttgtc acaaacagga
      481 tattcttatg tccattctgg atcaaaaatt ctgttgcttg tttacctaga agctggttat
      541 cattatctac ataaacgatt tcgttctcat gatgataagg ctgtccgatc aaagtgaaag
      601 ggatgtggtt ttggtataaa taatcaatga cagtatcttg actatctgaa tacactagaa
      661 taaaaccatc tacttgtttt tgtaaatgca tacgctggac gttctctaac agcaattcaa
      721 aatttttagc agtagcgatt gctgtagtca tatcataatt ccgcgcttct tcgttgattg
      781 cttccatgat ctcaagataa aatgggttac cgatccgctc ttttgaatca agagggggta
      841 agattacgcc gatggcactg gaaatgcgtt ttcctagatt gcgggcagtc atgttaggaa
      901 cataacctag ttcatccata atttttcgga ctttcttctt tgttgtctcg gaaatactag
      961 gatgatcgtt gatgacacga gagacggtcg aggtggcaac accggctttt ttcgccacat
     1021 cttttacggt aatagccatg ataaaaacac ctttctcttg ttattgtgca gagaaccgat
     1081 aaatcgtctg actgatccgt tcttgaccag gatggaggtt gatcgatcca aatttgggga
     1141 aatgaacgat atcagggatt tcttgcggtt cgattgctaa tccgtagttt gaatgcatct
     1201 gttttccatt gacagagaaa tcagcttcga atccagtcgt agaaaataat accatacttt
     1261 tattagaagt tgctatagtc atttggcgac cagaatgctt ctcgaataat tgtaaggaag
     1321 ttttggaaag cctaggatga tgcaaaagaa atacatcatc tagtccatct ggataacatg
     1381 caaggatctc ttgcagtgtt ggggattttc taaagtcgat tggcagtttt tctttttttg
     1441 tccaatttcc agtaggcagt ttttcttgat ctaattcaag cacaccatct aaaaagaccg
     1501 ttaactgatg ttcatagatg tctcttgttc catttcctga aaggttgaag taggcatggt
     1561 tggtcggatt gcagatggtt tcaacaaggc tactagcaga ggttgtcatc tctaattcgt
     1621 tttttgttaa acggtaagtg atcgtagcag tgattggtcc tggataggta gaaaattcat
     1681 cttttaagta aaagaccaca cctattgatg atggagtttt gaaaacttct acttcccaaa
     1741 attggaaaga ccagcctttc gtgccaccgt ggatatggtg tgatccgcag tttttctcca
     1801 atctatgctc accccaagaa gcatcccgga tccttccggc tacaggtccg acagttgctc
     1861 caaaaaagct tttgtctgtt agaacatctt cgaaacgatc gtaagacaat aaaacatttt
     1921 ctgattttcc ttctttgtct ggtgcgaaga tttggtgcag gcgggcaccg taattgagaa
     1981 gaacgacttc taagtagtcg ttcttcaatg tgattttctt tatttcagtc tctggaactg
     2041 gtacgacgga gatctctgga ttatccatgg tcatgccact tttctttcaa gtaatcgatc
     2101 gtaagaaaag tcgtatcagg gacaagcggg atctcctctc caaggtcttc agcacgtccc
     2161 acgccaattg gttgagcgcc acttgagagg atggcttgga taccggcttg cgcgtcttcg
     2221 atcccgatac attcttctgc ttttagtccg acagcttttg ctgcaaggag gaagatatct
     2281 ggcgcaggtt ttccgtttgt tgcttctgcc gggtcggcaa tagcatcaaa gtaaggtgta
     2341 agacccattt tttcaagtag gaatggcccg tttttacttg cagaagcaag agcaatcttg
     2401 attttttctt cttttaaaga atccagtaaa ggcacgaccc cggggaagac atcttttggt
     2461 tcgatcgtct ggatcatctc taaataataa tcgttttttc ttttcgctaa ttctgcaaat
     2521 tcttcctttg aaaaagagtg ttcttttccg ccataagcta aaagcaaaga gagtgagtct
     2581 tctcggctga cgccttttag ctgttcgttg aatgtgtggt cgatcgtaat gccgatttcc
     2641 tgaccaagct ttcgccaagc acgataatgg aattcagcag tatcggtaat gacaccgtct
     2701 aaatcaaaca ataccccttt aaacatttgc ttcctccttt cttagcgtta tttctagacg
     2761 atccgctaaa gaataagact gttcatagac gtaaatttct agaggagaac cttctaataa
     2821 ctcgaaagta acttgttcat ctgtgactga gatgaacaat aaacgtccgc gataattgat
     2881 atggaaagaa taagctttcc aagtttttgg cagaaatggt gcgaatctca actgatcatg
     2941 ggcagttttc atttgagcaa atccttggac aatcgacaac cagctaccag tcatggaagt
     3001 gatgtgcaag ccgtcttctg tgtcgttatt gtaattatcc aaatccaagc gagctgttcg
     3061 ctggtacatt tctacagctt tgctttccat tcctaattct gctgctaaaa tcgaatggat
     3121 acttggcgaa agggaagact catggacagt cattggttca tagaaatcaa agtttttttg
     3181 cttttcttct tttgtaaaag tatcattgaa gaaataaatc ccctgtagta catctgcctg
     3241 cttgatgaag caagatctaa ggattttgtc ccaagaccaa tgctgattca gaggaagatc
     3301 gcttgtggga atatcggata caggcatgag atctttatct aagaatgtgt catgctggac
     3361 aaagattcct aattcttcgt caactgggaa gtacatgttc tctgcgatat ctttccattt
     3421 ggctagttct tcttcgctga tagtgatagc agcttctttt tgataagtta aataattttc
     3481 tcgcgtgtaa cgcaagaccc aagctgcgat cgtatttgta taccaattgt tattgatatt
     3541 gttctcatat tcgtttgggc cggtcacacc gtggatcatg tatttatttg ctcgttttga
     3601 aaaatggaca cggtctgccc agaagcgtgc gatttctgct aaaacttcca gtccttcatt
     3661 tttcaaatat tccgtatcgc cggtgtaatt cgtataattg tagattgcat aggcaatcgc
     3721 gccatttcgg tgaatctcct cgaatgtgat ttcccactcg ttatggcatt cgacaccagt
     3781 gaaggtgacc ataggataaa gcgcgccttt taatccttgt tgctgagcgt tgtggattgc
     3841 ttgcggcagt tgattatgcc gatatttcag cagattctta gttacttcag gtttggctaa
     3901 agcaagataa agagggacag catacgcttc tgtatcccag taagtggctc cgccgtattt
     3961 ttctcctgtg aatcctttgg ggccgatatt caatcgttca tcttcgccgt agtaagtaga
     4021 gaatagttgg aacaaattga atcgaatacc ttgttgtgct tcttcgtctc cttcgatgac
     4081 cacatcggca agcttccatc gttctgccca agccgctgtt tgctcttctt ttgcttggat
     4141 ataattgttt gtctggttcg ttaattctga gacagctttt tctgcttgct gcgcttctgg
     4201 aatatctcta ctagtaagaa cgataatttc tttttccact gaccatgtct caccttgaga
     4261 taattctgca gacaagcaac catgtaatgc taaagtatct tcgtgatagt cagggatgac
     4321 tgattttcca ttaacgaaat ggcgcattgc tgcagtaaca gtaaattgtt caatcccaaa
     4381 gttgtttgga atagttttag tcgtcaaata gccgatttct tctatagttc cacgatcaat
     4441 ctcattccaa aaatgttcat catagttgct gtcttcgttt tgaacatttc catccaattt
     4501 tgatacgagt ttgactgttc cgctaccttc aagcatttct atagttaaat agatataagc
     4561 tgattctttt ttgacaatgc tcagaaaacg ttcgaaggaa atgcgtactt tattagtaga
     4621 agtagtgatt gtgaatgtac gagataatac accatttttc atatctaatt cccagtaaaa
     4681 gtcttctggt tccaaagaag ccaagtcgat cagctgatcg ttgatcgaaa tatctatcgc
     4741 gataaagttc aaggcgttga tcacttttcc aaagtattct ggataaccat ttttccacca
     4801 gccgacacgt gtcttatcgg gataccagac acccgccaaa taagtacctt gatggtggtc
     4861 ccctgagtaa gtttcttcaa agttcccgcg catccccata taaccgtttc caatacttgt
     4921 taaagattct tgcagtcgaa gatttttttt atctaattgt gtcgtgctga ttttccatgg
     4981 atcaatagca aatagtcgtt tgatctgttt catttttctc ctcctaatga gctgttttat
     5041 acgttcataa taaacgcaac cgattgcaca agtcaataga caaaagaaaa tatttcatag
     5101 aaaaaagctt aaaaaaataa atttttagga gaaaattata gaagggaaca cacgtattat
     5161 aggttttata gaatggtata gacagaaaaa taaaaaataa agcatttaca aaaaagaaaa
     5221 cgcacgctat aatacgttta acgaaaccga ttgcgtaaag gagctaaacg gaatgaaaaa
     5281 gatatttagt tttgagtttt ggcaaaaatt tggaaaggct ttaatggttg tggtagcagt
     5341 tatgccggca gctgggttga tgatcagtat agggaaatca attcccttga tcaatcctga
     5401 ttggacgccg cttgtcacaa cgggcggagt aattgaaaat attggttggg caattattgg
     5461 taatcttcat attttatttg ctttagcaat aggaggaagt tgggcaaaag aaagagcagg
     5521 cggagcattt gcagctggga tctcatttat tttaatcaat cggatcactg gggctatctt
     5581 tggtgtcaca agtgacatgc ttgcgaatga agatgcattt acccacactc tgttcggtac
     5641 gaagatcatg gttaaaggat tttttacaag tgtattggaa gcaccagctt tgaatatggg
     5701 agtattcgta gggatcatcg ctggatttgt cggggcaatg gcttataata agtactataa
     5761 ttatagaaaa ttgccggatg ctttgtcatt tttcaatgga aagcgctttg ttccgtttgt
     5821 tgttatctta tggtcaacaa tcgtggcatt gattcttgct gtggtgtggc caaacgtaca
     5881 ggctggaatc aataattttg gtttatggat tgcagaatca caagaaagcg caccgattct
     5941 agcaccgttt ttatttggaa cattagaacg tttactattg ccatttggat tgcatcatat
     6001 gctgacgatt cctatcaact atacacagct tggcggatcg tatgagattt tatcaggcgc
     6061 acaggcgggg acacaagtat ttgggcaaga tccgttatgg ttggcttggg ccactgattt
     6121 agtgaatctt aaaggtgcag gggatatgtc gcaatatgag tttgtgttgc ataactggac
     6181 gccggctcgt ttcaaagtag gacaaatgat tggttcttca ggtatcttga tgggaatggc
     6241 ttttgcgatg tatcgtaatg tcgatcctga taagaaagca agatataaat caatgtattt
     6301 ttcagcagcg ttggctgtct ttctaacagg tgtaacagaa ccattggagt tcatgtttat
     6361 gtttgctgct gtgccattat atgtcattta ttcagtgatc caaggggctg catttgcgat
     6421 ggcagatatc ttgccattgc gggtccattc atttgggaat atcgaattgc tgactcggac
     6481 accgttagct atcaaagcgg gtctaggtgg agatcttatc aacttcgtgt tgtgtgtgat
     6541 cgcttttggt gttgttacgt atttcttagc aaatttcttg atcaaaaaat tcaactttgc
     6601 tacaccggga cgtaacggaa attacgacaa tgacagtgaa gaaaccgttg tatctaacag
     6661 cggaacagga acagcagatc agcaagtggt ccagatcatt catttgctgg gaggaaaaga
     6721 aaatatcaaa gatgtcgatg cttgtatgac tcggttacgc gtaagtgtaa atgatcgaga
     6781 aaaagtaggg actgaagaag cctggaaacg agcaggggcg atgggattga tcgtcaaaga
     6841 caatggagtc caagcagttt atggaccaaa agcagatgtc ttgaaatcag atatcgaaga
     6901 tctgctgcaa tcaggagcag agattccaga gccagaaatg gtttctacag gaaatggaca
     6961 agcaggtagt aagcaatact taggtataga acaagaacta gtttccgcag cttctggaga
     7021 agtgattcct ttatctgaag taaaagatcc ggtattctca caaaaaatga tgggtgacgg
     7081 ctttgctgtt attccaacat caagagaagt tgttgcgccg atcgctggaa aagtgacaag
     7141 tattttccct agcaaacatg caattgggct ggaaacgaaa gatggtatcg aagttttgat
     7201 ccatatggga atcgatacag tccaaatgaa tcagccagct tttgagattg ctgtcaaaga
     7261 aggccaagaa gtaggaacag gaacgaaatt agctgagatg gatcttgatg tgatccaaaa
     7321 cgaagaaaaa gatccaacga tcatgatcgt atttacaaac gataaagtag aagaagtagt
     7381 gatcaagcaa ttaggtacag tgacagctgg taaagtgatc ggctccatta aaatgtaagg
     7441 agaggttgtg aaaaagctgt cctgcatcaa gtcataagaa cagccaaaca aaaatagctc
     7501 ctcctatttt tcgtttggtt gggcttatta ccgagaagca gcagtttgaa tactgtttag
     7561 tggagaggtc gtgaaaaagc tgccctgcac caagtgataa aaacagccaa acaaaaaata
     7621 gctcctggtc cattgagctt attactgagg agttagcagg agaacactat ttgctggaga
     7681 ggttgtgaca aaaattttgt cacaaccctt ttgtttcgaa atgaagacaa ggagaaaacc
     7741 aatgaaattc atgacactca acacgcatag ctggcttgag ccagaaccag agaaaaaatt
     7801 gcaagaatta gcagataaga tcctgttaga agattatgaa gtgattgctt tacaagaaat
     7861 caaccaatta ctggaatctg aagaagtaga acctgcgaag ctaatgaagt tctgtccggt
     7921 aaagaatcaa gtacctatcc gtaaagataa ttttgcctac cgtttagttc agcttttaaa
     7981 ggaacacgga aaagagtatt tttggagttg ggaaatgagc cacatcggtt atgataaata
     8041 tgaagaagga aatgcactgc ttacgaaaaa aacattggaa agtcaggtcc ttaccgtctc
     8101 ccaatttcaa aagaaagaag attatcagac acgcaagatc ttgattggga aaacaaagat
     8161 agatgatcag gacatttttg tctcgagctg ccacttttct tggtggacag ataaaaaaag
     8221 tggcttttat tttgagtgga aaaacttgga aaactacttt ttggaaactc gcgtaccact
     8281 ttttttccta ggtgatttca ataatccagt agactctcaa ggttattata ctgtaagaga
     8341 aagttgcctt cttcttcaag attcgtatgt tgtcgcgaat gaaaaaggaa aagcagctac
     8401 tgtggaaaag aaaatagatg gttgggaaca aaatacagaa aaattgcgta tagattttat
     8461 tttcgtccct gaaggaatgc aggttaaaaa atatcaacgg atttttgatg ggatcgatag
     8521 tccaatcatc agtgatcact acggggtgga aatcgaatta gatgtgaacg aataaaaaat
     8581 ataacatata acataaaaaa actgattaaa ataaaactct ccaaacgatt ataccgtttg
     8641 gagagttttt tgatcggatg tatttatccc ttttgcctaa gcacgtaaaa gcttgtatct
     8701 atgataaata aataaacata gcaaggtaaa ccagccaatc aaagtaagag aaagaatgaa
     8761 atagaaatag attggcgttt gataatgaag cgtgagctcg ttgattcctt tttgctgctt
     8821 cacgattggg gtcccgatat ctgttacttc ataatcagtc aatgtttttc cattttgctg
     8881 tagcacagtc cgatcgtaga cgataacagg gatatgaaca gttttgtccc cagtgttttt
     8941 ccacttgatt gtcaaaagac cgcctggatg tgtttttata aaagttgttt cgttttctag
     9001 tatttcttcg ttataccggt cgtatttatt gtcttttgtc tccttataga ttggcagata
     9061 gtcaggtgtg gttttttgga aaacgaacaa gctggtagac atatctttgc tgaagaatgt
     9121 tttccttgct tcttccggcg tatcgaatag ataagtatgt cgactgacaa atgtttcatt
     9181 ttcccacttt tccagatgct ggtataagtt ctggatcgtc tgtgctgaaa aaataagaat
     9241 gccaaatata cttaaaagac ggaaccactt ttgttcagac cactggttca gtgaaagggc
     9301 aaggtaaagt agaagcaata gcgtaaatgg cacgaaaaat cgaaatggaa actggatcaa
     9361 actaataaaa ggcacatttt tttcgatcaa tgtcgtccat ggaatcaagc tagtagaaag
     9421 aaaaaagaaa acaagacttg tgtacaacac gattttttgg aataaggtgt tcttttgttg
     9481 aaagaaaata aaaagcaaaa aacctgataa tatcaatata ggaaaggcct tagggtaatg
     9541 gagccaataa ctgccatcca gatctatcgc cttttgactc atttctctgt taacaaaggg
     9601 aggaagaatc ttattcccac tgtaaacaat agctaatcct gcccaaatat ttgctgtcag
     9661 aacaaaataa agcaagaccg acttaatcag ttgaagcagt gcttttcctt tttcagtctg
     9721 gttaaaaaag taataaagat aaaaagggat atacatcaaa gctaacatga tcgaagacag
     9781 taaatggatc tgtgtcataa gtcccactga gacagcgact ttgataacag ggaacttttt
     9841 atgaaggacg aaatcagcaa tagggatcat acataaagga taaaaacaag tcccccagct
     9901 agtgaatcct tggttgatag accagtattg aatagaatac gtactcatga ataaaacggc
     9961 tactggtaca cttacccaat ttcgaacatt gacatatctc agtaaaatca gcatagaaaa
    10021 tcctgaaata agataaagaa tgaaatttga aagaatctga taatgaaacc agctacctgc
    10081 aagcaacacg atcaatcctt gtaaataagc gaaaaatggg ccgtaaacgg cattcacgat
    10141 cctgccactt tgctggaatc cataaaggga aggaaaataa tggaaatccc catatttaat
    10201 ttgttgcgcg gcatcataga accgattgta atggaatggg gcatcagcac ccaaaattag
    10261 tttatgtgtg aataaatgag gcatgagaaa tgccaaagca atgaaaaaaa ttgctaaaaa
    10321 tgggccatat tttttcaatt gtcgaactcc tttgcaaact ttagataaat tcatcatata
    10381 tcctatgcga gaggtaggca agaaattaga aaattcatga aaatatttat gaattttaca
    10441 agaaaaacat aagtgaaagt tctaaggaga gaggatgcga cataagtttt gttgcatctc
    10501 cttgttttga aacagaattt ttcttaatac tcgaaacaaa gtagcttttt catgacctct
    10561 cggtaaacgg tgttcaatca gctgcttctc ggtaataagc tcactagcct agaaaatatg
    10621 agaagctatt ttctgactag cgctcttatt actcaaagca taacgcagtt ttcacaacct
    10681 cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc caacaaaaaa
    10741 tatgagtagc tatttttttg ggctgtactt attacttgat gcaggacagc tttttcacaa
    10801 cctcatcggc tttcattttc tatttttttc ctgaacccat ataataaaag aaagaacaaa
    10861 aaaacttgca agggaggaca catgtgaagc agagtaagca aaaacagtct cgtcgacttt
    10921 tgtttcgttt gtttttatta atatgtatcg tcgtagggtt actgatcgct ttatatccat
    10981 tttatgtgga ttctttaaat agttttattg atcaaaaacg tatcgaacaa gtacaaaaac
    11041 ggaccgcagc tgaaattgaa gtgcagcgaa agaaaatgga ggagaaaaac caacgattaa
    11101 ctgaccaagg attcaatcct ggtactgatc ctttcaatga aaagaacaga aatgaaagta
    11161 caacatccag ccaattagag gaatggctga tcggaagtat caatatacct aagatccaat
    11221 taaatatttc actttatgat cggctcaatg gtaggatcct tgaaaatgga gcaggcgtct
    11281 tgcaaggaac ctctttcccg cttggtggaa attcgacgca ttcagtgatc tctgctcaca
    11341 gcggtttacc taatcgacgg ttatttaccg aattagatcg tttagaaaac ggagacacgt
    11401 ttattttgac tgttttgggg gagaaattgg cttatcaagt taaaaatata caagtggtac
    11461 tgccagatga cacgtctgtt ctaacgattt cagaaggaga agacttagtt accttgctta
    11521 catgtacgcc gtatatgatc aacacgcatc gtttgctagt gacaggacat cggattcctt
    11581 ataacgaatc ggtaaaaaaa gaagaaggaa aaggaaatca ggaaagaacc atgcggcaat
    11641 ggtttattct tgcaggaacg ataatagctg tagtcatact gttagtgttt atcggacgac
    11701 taatctatca gtatagatta agtaaaaaag tgcttgattt ttcatttatt attagtgatt
    11761 cgtcagggaa accggtaaat ggtagttcat tcattttgaa acataagaaa aaaacactta
    11821 ctagaaatgg tgtgccgttt tcagtacaaa gcgaccatca tgggaaagtc aagctggatc
    11881 aattgcctgg tggaacttat cgaatcgttt cagctgatga tcctaaagtt gctgtttctt
    11941 ttggtattag aaaagtaaaa caagagaaga tatacttttt tgaggggcga aaacttgtaa
    12001 aagagcttca aaaaaatggt ttttatttta aaatcaatga ataagtaagg agagaaaaaa
    12061 tgatccgcac aacaacaaaa ttgtctgcca aagaactgga atctgttcta tcgatttggc
    12121 tgcatgctaa cttggattct catgaattca ttccatcaac ttattgggag aatcaagtag
    12181 aatctgttag gaaagcttta ccagatgcag tgatttactt agcagaaata gatcaagaaa
    12241 ttattggttt tgctggggtg attgatcagt ttatcgcagg aatctttgtg aaaagggaat
    12301 accggcaaca aagaatcggt acgcaactaa tgaaaaaaat aaaagaaacc aataaaacac
    12361 tgactttgac agtctatcaa aaaaatcaat cagctattca tttctatctt tcacaaggtt
    12421 ttacaattca aacacagcaa aaagatgaag cagtaaatga ggaggaactt gtgatgaaat
    12481 ggaatcaaaa cgctgatttt tgatgaacag aataacgaaa taatgctccc agcctaattt
    12541 tttgctggga gcattatttc attttgaagt cactaattta actgtgtgaa tatgcagttg
    12601 ttacaatctt tgataaacgg tgttcaatca gctgaccctc ggtattagct caaaaaacgg
    12661 caaaatatga ggaactattt ttccatttgt ttctctaata ctcaggtcaa aacgctgatt
    12721 tcacaacctc ttgataaacg gtgttcaaac ggctgcttct cggtaataag cccactagcc
    12781 tagaaaatat gaaaagctat tttctaacta gcgttcttat tactcaaagc ataacgctga
    12841 tttcacaacc tcttgataaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa
    12901 cggcaaaaca tgaggaacta tttttccgtt tctttctcta atactcaggt cagaacgctg
    12961 atttcacaac ctctctttca caaccttatt ttactcgttt ataattttca tcgaagtatt
    13021 ttccgctacg gatatcatct ggcattccat cgtatggttc ttcgctaata acatcttcat
    13081 tgtctatacc tgcatcaccc atataagtga tcgtagcaaa ttcaggaaca agtaattttg
    13141 gataagtttc atatttttca cgagctgctt ccatttctgc gatatgttcg ttttggaaag
    13201 taacagtgat ttctggatgt tcttcaaccc atttagggaa aaagatcatt ccgtgaagtt
    13261 tcttttcatt tggcataaag tccaatgcca cgtctgtccc tgttggctct gtccaagtga
    13321 ttttgaatac gccgtccgtc aatttaacga tatcagcttc ttggtctttt acccaacggc
    13381 ctttgaccat tccgccatgg atacggtaat caacagtatg gtcatttttg gcataccatt
    13441 catattccca accattgtca tacgtataga taaagtgagt tccaataaaa tcttccaatt
    13501 ctttaaattc tttcatgttt aagcatctcc ttataaatta aaacatgtaa taaactacat
    13561 gttttcgatt actcatttat gatagaatgg atttaaagat ttgtcaagga gggaaaactg
    13621 atggcaagaa aaaatacact tcgatatatt ttgttagggt tattaagtaa gaagaagatg
    13681 acaggatatg aattgaatca atcgttcaaa aatgaaatag gagaattttg gcaagcaaaa
    13741 catagtcaga tttatcctga acttgcaaaa atggaagagc aaggaatcat tcagcatcaa
    13801 gtagagatca caggtgaaaa attggaaaag aaagtttatg aattaacaga agaagggaag
    13861 gaacaattgg cagagtggat tcatacaccc accaatgaac taccggttaa tcgagacgaa
    13921 tttgttctga aattgtattt cgtcaaagac gtgaatgatc cggcattagt agaaattatt
    13981 cagcagcagc gtgaccttca tgaagaaaaa cgacttcatc tattagagcg aaaaaaaacg
    14041 atctttccta ctgaaaaaga aaaacatgaa aattacggac actacctgat tttagcgcat
    14101 gcgatcaatc gggaaacaga atatgcaaat tggctaacag atgtattaga agaaagtaac
    14161 cgaaaaaaat aaaaaaatat ccgaacagtg atggagaatt cctttctata tgaaagaaac
    14221 gcagatcacc gttcggatat tcttatgttc aaacaggcct tttttcaagt atttatgtag
    14281 catctactta ttaaaaagct tggtacttag gagattagtg gcgtttagag ttcttttaac
    14341 aactgttcgt agtcagcttt ttcatcgaca ggaaggagct tgtaagttaa ttcgtctgtc
    14401 tcgttgtcat gaatgatgta catcttagca ttctcttctt tgaagttacc gatttgtaaa
    14461 atcgtatagc gttcgtcgat caattcgata tctttgattg cttttgaaaa aactttacgg
    14521 acatggtgca ttttcttttg gcggatttct gccttttctg cagcttttga caaagtaaat
    14581 ccgtcatcta aatatttttt gatcagttct acttttatga ctgtaggtaa acgatatttt
    14641 ctaggacaat tcgcatcagc ttcgatcgaa cgaatgaatc ccttttgttc ccaatacctt
    14701 aattgacgtg gagacacacc tacgatatca cttaattcac tgatgccaac aaccaattga
    14761 tcattttcca acaaacgttt aagggaagcc ccaaccattt ttgtcactcc ttttgtcctc
    14821 ttgcttccct taattatatc cgtattaact tatgtgtcaa gtaggttgac aaatagcgaa
    14881 tttaggacta aagtattcta gtagtttcag aaaaaattca gaaagaagga gaaatatgag
    14941 taacaaccaa cccgtagata tttacggaaa accatataat cggacacttt tagttgttgt
    15001 cttattaatt ggtacatttt gtaccgtttt gaatcagacc ttattgacga cagcttttcc
    15061 tacattgatg aaagctttcg atatttcagc gtctgatgtg caatggttaa cgactggttt
    15121 cttgctagtc aacgggatca tgatcccaat aacagcatgg ctgatcaata aattcagttc
    15181 aagaaattta tatctttctg ccatgacgat ctttttgatc ggaacgatta cttgctttac
    15241 agcacctaat tttagtacat tactaatcgg tcgtttgatc caagcttgcg gtgtgggagt
    15301 atcgatgcca ttattgcaaa atatcatgct atctattttc ccgccagaaa aaagaggatc
    15361 agcaatgggg atgtcaggga tcgttattgg acttgctcct gctttaggcc ctacattatc
    15421 tggttatatc attgataact accattggcg tgacttgttt ggtatggtac tgccaatcgt
    15481 tgttcttgtc ttggttttag cattcttcct aatgaaaagt gttattccat tgtcaaatcc
    15541 tagcattgat attttatccg ctattttatc aacgattgga ttcggtagtt tactttacgg
    15601 attttctagt gtaggagatg acggctgggg aagcttgaaa gtaattggtt tcttagttgt
    15661 tggtgtgatt ttcatcgcct tgttctcatg gcgtcaatta catttggaac atccattctt
    15721 ggaacttcgt gtattcaaat catctacatt cacgattgca gctgttttag ctggtgtaac
    15781 aaatatggcg atggtagggg cagaaatggt cgtaccattg tatattcaaa atattcgtgg
    15841 agaatcagca ttccattctg gcttgatgtt gttgccgggt gcattgatca tgggggctat
    15901 gatgcctgtg acgggtgcga ttttcgataa atacggcgcg aaacgtttag ccatcacagg
    15961 gatgttcatt ttgacagcgg caactgcacc atttgctttc ttgacaaaaa cgactccagt
    16021 tttatatatc gtgatccttt atgcgatccg tatgtttggg atctccatgg tcatgatgcc
    16081 ggtaacgact tctggtatga atgcattgcc aaataacttg atcagtcatg ggacagcggt
    16141 aaataataca ttccgtcaaa tcgcaagctc gattggtaca gctattttga tcagtgtgtt
    16201 gacgaatgtg acaaaagcaa atatcccaag caaatctgta ttggataata cgccattagc
    16261 ttataaagat caggcaatca atgccacact gtcaggttac catgccgcgt ttatcgtagc
    16321 gatcatcttt gggattcttg gctttattat tgccttttta ttgaagaaaa aagaacctgt
    16381 tctaatgaaa gcgggggata atgcatgatt attggagttt tgattgtcag cttgcttgct
    16441 tttgctttaa cgaacgtgtt cgctaaaaaa acatggcaaa cctttttatc tttgattttc
    16501 ggactaatct tcgtcgcttc actaagtttg atcgtcgcta atttgtccaa tcactttgga
    16561 atggaaaaag taacggaaac aaaaacagaa aaaattgttt ccagtgctga ttcccaagga
    16621 gcagatatgc ttttgtataa agctttaggg aatggaaaag aaaaagtgta tctttaccga
    16681 acaaatgaaa aacaagaaaa accaaaagca actggtacgg ataacgaaac aaataaagta
    16741 gaaaagacag acggcgatgc tgaaaaagtg acgaaaacta cttattggga atacaaaaac
    16801 gacatgtata aattctggtt caatattgct gataacaatc acgaatatga cagccgagtg
    16861 aatacattca aaatcccaga gacatgggta gaattaagta cggaccaagc agccaagtta
    16921 gctgaattag tgaagaaaca gcaaagtacg atggaaagtg aagcaaaagc ttatgttcaa
    16981 gacggtatgg taaaagcaat gactgaaaat ccaaaaatga gcaaagcaga gcaagaacaa
    17041 cgtacgaaag ccttagctgc tgaattccaa caacaagcat tcgcaaaatt agtgaaagaa
    17101 gcaaaaggcg aataatattt tgaacaccat gtaggaggtt gtgaaaaagc tgctctgcat
    17161 caagcagtaa gaacaatcag
//
LOCUS       DAFEEZ010000059        17162 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000059
VERSION     DAFEEZ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17162
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.062"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            7..1398
                     /locus_tag="LP245_002148"
     CDS             7..1398
                     /locus_tag="LP245_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBL1520043.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIETSGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            1414..2454
                     /locus_tag="LP245_002149"
     CDS             1414..2454
                     /locus_tag="LP245_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL1520044.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            2473..3558
                     /locus_tag="LP245_002150"
     CDS             2473..3558
                     /locus_tag="LP245_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBL1520045.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            3591..4553
                     /locus_tag="LP245_002151"
     CDS             3591..4553
                     /locus_tag="LP245_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBL1520046.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            4546..5979
                     /locus_tag="LP245_002152"
     CDS             4546..5979
                     /locus_tag="LP245_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBL1520047.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKGELI"
     gene            5976..7046
                     /locus_tag="LP245_002153"
     CDS             5976..7046
                     /locus_tag="LP245_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520048.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            7033..8454
                     /locus_tag="LP245_002154"
     CDS             7033..8454
                     /locus_tag="LP245_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBL1520049.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFITIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            8467..9474
                     /locus_tag="LP245_002155"
     CDS             8467..9474
                     /locus_tag="LP245_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL1520050.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            9486..10490
                     /gene="neuB"
                     /locus_tag="LP245_002156"
     CDS             9486..10490
                     /gene="neuB"
                     /locus_tag="LP245_002156"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HBL1520051.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            10487..11635
                     /gene="neuC"
                     /locus_tag="LP245_002157"
     CDS             10487..11635
                     /gene="neuC"
                     /locus_tag="LP245_002157"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HBL1520052.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            11608..12285
                     /locus_tag="LP245_002158"
     CDS             11608..12285
                     /locus_tag="LP245_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBL1520053.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            12275..13417
                     /locus_tag="LP245_002159"
     CDS             12275..13417
                     /locus_tag="LP245_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBL1520054.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            13430..14407
                     /locus_tag="LP245_002160"
     CDS             13430..14407
                     /locus_tag="LP245_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL1520055.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            14407..15315
                     /locus_tag="LP245_002161"
     CDS             14407..15315
                     /locus_tag="LP245_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HBL1520056.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            15316..16068
                     /locus_tag="LP245_002162"
     CDS             15316..16068
                     /locus_tag="LP245_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBL1520057.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            16073..17020
                     /locus_tag="LP245_002163"
     CDS             16073..17020
                     /locus_tag="LP245_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBL1520058.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         6183 a         2196 c         3103 g         5680 t
ORIGIN      
        1 gtatatatga ataaaaatgg agaatggagt gctgcacgac ggatattcat tatattaatg
       61 gatgttattg tatacaatgc agcaatatat agtagtttct tactgaagtt tcgtggagag
      121 atcccattac gaaatttaga aactttccaa cactcagcaa ttattatttc agtgattttt
      181 attgcgttga acattttgtt gggtgcatat gttttttata atcgaatgat cagtgacatc
      241 gtgtttgtca cagtcatcgg tcaggtattg atgacactag ggatcatggt agtgactttt
      301 gcgggccgct ggtttgcttt tccacgtctt gttatcttac tttcatttgt tctcggtacg
      361 cttttcttaa gtatctatcg tattctcgta tataaacttt atttacgcgt aagtcgagat
      421 aaaaaggtcg tcattattgg gttagaaaag gatgtcgcac cagcaatcca aaattttggt
      481 tcaaagaaaa acaacaaaca taaagtcgaa gcagtcattc ttgataacta ttatgcaaac
      541 atcaaaaata tgattaaaga catcgatatt gtctatcttg cttctcatat cgaagaaact
      601 gaaaaaatca aaatctatca attagttact aaaaatgaaa aaaaattgtt tttgaataca
      661 acatttgaaa acttgacatt gatcaatcca aatattatga atttcgaaga tgaaagtatt
      721 attgaaacat ctggatttag aatccaacct gaatatgaac tattcaaacg tttgtttgat
      781 atcatcgttt cacttgtttt attagttatt gcttcaccat ttatgttatt cacagcaatt
      841 ttagtcaaag tgacatcacc gggaccaatc atctataaac aagtgcggat cacaaaaaat
      901 caaaaggaat tttcaatcta taaattccgc tcgatgaccg ccacagccga agcaaaatct
      961 ggaccagttt tagctaagag caatgatgca cgagtaacgc ctgtaggtaa atttattcga
     1021 gctgtccgct ttgatgaatt accacaaatc ttcaatgtgc tgaaaggcga tatgtcgatc
     1081 gtaggaccac gtcctgaacg tcctttcttc gtcgatcagt tcaatgcaga aaacccttat
     1141 tactacttac ggcataatgt tcgtgctggt atcactgggt atgcacaagt ctatggaaaa
     1201 tatgtctctg attacaacag taaattacgt tttgatttac tttatatcaa aaaatattca
     1261 ttgatgcttg atttaaagat cttgctgcaa accatcaaga tcctatttga taaaatgtcc
     1321 tctcaaggac ttgaagaaga cgaaaatgtg atctcattgg cagaaattgc ttttccgaat
     1381 gaaaaaatct ttcgctagtt gggaggcgta aaaatgaaca atccgaaatt cagcataatc
     1441 gtaccagtat acaatgcaga agcaactatt ggtcgaacga ttgatattct aaaagaattg
     1501 gattatgaag agtacgaagt cgttttagta aatgatggat caacagatca aacacaggaa
     1561 atcattcaag aactgattga aaatgatgaa cgttttgaat tgattactac gaccaatcaa
     1621 gggcccggat tagcaagaaa cgaaggaata agacagtcaa aaggagaata tctcttattc
     1681 ttcgatgcag atgacacgcc agtaaaaacg atcttgtcag attatgatca tttgctagaa
     1741 aagagtccaa aagcggatct tgttgttagt tcgtttgttt ttcgtacaat ggacgaggga
     1801 agaatcgttt ccgaaaaaga aaacttagtt acagaatgtc actatctaac tcacgaagag
     1861 tttataaaag acatgtatca gttaatgaat gaacagttga tgtatgttgt atggaacaaa
     1921 tgctatcgta gcgatattct gaaaaataac caaattctat ttaaaactta taatagttgt
     1981 gaggatcgaa tatttaactt acattattat gaatactgtc atcaagtgat catgaaccca
     2041 aaagtagaat atatttatga atttgaaggt gggaagggga tcactaatca ataccgacct
     2101 aacaagttcg aaacatttaa agaattctat tcattagcaa atactgtaac agacgatatt
     2161 aataaagacg gtatggcggc gcttctttta aaagggacaa cttcagttat tttttctatt
     2221 tatagtacct ctgcaagaac ttcaaaagag aagaaagacg aagcaaagca gatattgagt
     2281 gatccagtga tccgagaagc caagcaaatt gctaagacgg attcttcagc aaaaaaaata
     2341 acaaagttgc tttacaatat gccagctcca ctatttttat ctgctgtaaa agttggaagc
     2401 ttcgttgaag tgaaaatgcc agggttaatg gctgctttga agcgagtata ttagttaatg
     2461 gaggaaaata taatgaaaag aattttgcat tttcagggac gaatgggttt aggtggagca
     2521 gagtctttca tgatgaattt atatcgtaaa attgatcgta caaactatca atttgatttt
     2581 ttgatttatg aagattatgc agatgttcaa gactatcatt cagagattga aagattagga
     2641 ggccgtattt ttgttgtacc taatcctaag aaaaatattt ttaaatattt aatagaagtg
     2701 aataagttac taaaaaaaga atctttttct atagttcaca atcaggttta ttttggcggg
     2761 ggaattaatt tatggttagc caaaaagaat ggaatcagac agagaattgc tcatagccat
     2821 gcaactgaag atggaaaatc tcaaaatatt gtaatgaatg tattgcgtaa atttttaacc
     2881 aaattgttgt tacaaaatgc aacagactac cttgccgtta gtcaagaagc tggtgaaagt
     2941 ctgtttcaaa accatccctt tgagatagtt cataatggta ttgatttaga gctttatagt
     3001 aaaaattcag aagctaaggt taataagaga aaagaattgg atatctcaat gagtactttt
     3061 gttgtgggaa acattggacg attagagaaa caaaaaaatc aatcttattt gttagagatt
     3121 tttttagaaa tactaaaaat gaattctgat tcttacttga ttttagtagg tgaagggtca
     3181 cttagaaata aactgaaagc caaagcagta gaattggata tagagaaaag agtaaaattt
     3241 ttaggagaaa gaaacgatat tcccgagtta ttatctgtga tggatgtttt tgtaatgcct
     3301 tctctttatg aaggtctgcc aatggttgga ttagaagcac aagcagcaaa attaaaatta
     3361 gtcttagcag atactatttc caaagataca aagttaacaa ataatgtgga ttttgtatca
     3421 ttagatgaaa caccacaaga atgggcaaaa aaagtaataa aagagccgta tgctaataaa
     3481 ataacacaag aactaaagag ttatgatgtt tcgtacacta ctgaacaaat ggagagtata
     3541 tatagtagag atcattaaaa atgttcaaga tattttagga gtgattattt ttgaaaatat
     3601 gttatttgat attggcatac aatgatattg gcaacttaaa gagattggtc aatcgattga
     3661 acgaaaatgc agtttttatt attcatatag ataaaaaaac tgatatagaa ccatttattg
     3721 aagcatttaa atcatatgat aatgttgaat ttttatgtaa taaaaaccgt gttaaaattt
     3781 attggggtgg tttttccatt gtacaagcag aaatcaattt agtaaagaga gcattacaaa
     3841 atgagaaata tttaaaatat gtattattat ctggtgctga ttatccaatc aaagataatg
     3901 agtatattta taattatttt aaaaagaata gttcagtgga gtttattcgt ggaatagatc
     3961 tagatcaaat taaacataaa gaattttatt ataaacatat agatgtatat caaaaacatg
     4021 attatcctag aattaatagg aataacacaa ctgcatttaa aatttttaga gctataatta
     4081 atcgttgtct gaggatgatt aaacttcccc caaaaattag acaccataaa tttgatttgt
     4141 atcatggttc tcaatggtgg gctttgtcga aagaatgcct aacagaatta atacaaatgt
     4201 atgaacaaaa tcaacaagac tacctgaatt ttaaaatagg tatgtttgcc ccagatgaaa
     4261 aattttttca tacacttttt tttaattcct cgttcaaaaa taaaaatgtt attggaggac
     4321 cagatttacc acttgaattg aaaaatattg aagaaactac tttacaaact tcgaaattag
     4381 caaatattca tattattgat ccttccatga acaaatggtt tgatgaaagg gatatagatc
     4441 aaataaaaga aagtgaaaaa ttatttgtaa gaaaagttaa atcggattac tctgataaac
     4501 tattaaatag aattgataaa gaaattttga aagttggaaa tatagatgaa tagaatagta
     4561 cctgttttag agaagagttt attaagtcga gatgcgtttc gagtaataaa tttaatcatt
     4621 tgtctgcttt attttatgcc tagtactttt aatgtaacta atatcccgat gaaaatagct
     4681 tttgcttggg gtggaattat agttttgtat gaggttttta taaagaaaaa tttttttaaa
     4741 atgcgttttt cttggctact gattggagca atgattagtt ttatcttaac tataatcatt
     4801 aacagagaaa attttttaat tccatctatt tataattttg gatatttgct gattactttg
     4861 atagtaattt ttcctgcaga cttttcacaa agtgaagagg aaaaaaagaa aaaaatggtg
     4921 tattttaata atgttttcat tatcataatt tttttagctg cgctaatatc tatctatcaa
     4981 tttatttttt tgatttctta tcatgtccca acaggaacgc caggattact tgcaagacaa
     5041 ggttttattg aacatcggtt atttggtgtc tatacaagtc caaatgttgg agctatgttt
     5101 ggatatactt ctattatttt aagtttaatt agtgtattaa tttcaaaaat aacaaaaacg
     5161 attcgtgttt tttatatgat gaattttatc gtacaaatat tttatattac actttcttcg
     5221 tctagaggtg cccaggtagt aatttgttct tttttagtat tatttctttt gttgtttgcc
     5281 aattcaaaat ttagaaagag cattagagaa gtactacctg taaaaatcaa atggatggta
     5341 agcatattat tagttctatt ggtatatttt tcttttggta ctaattatgc taaggatttt
     5401 ttagcaacaa ttcctgtatc gattgataga aaagtagaag ttatagagtc aaatgaatca
     5461 gataaaactc cacttccaga aaaagaagta atattacagc attctagtga taactccgaa
     5521 atttcagctg gtcgttttac gatttggaaa gctgcgctta aagttataag accaactttg
     5581 ttatttggtt atggagagac cgatttctat gggaatagcg atgcaaaatt tttgaaaaaa
     5641 gtagatcttg atactacaga tgtgaatgaa ctaaaaagag cacatggaaa catgcataat
     5701 ggatttcttc aagtacttgt atcaagtggt ataattgctt ttatatgtat ctatgctttc
     5761 tatgtgttaa atatctttag tttactcaaa acatttttta gaagtaaagt gaattatgcg
     5821 tttcttggta ttgttttaat ttttatacta tctattttta tagatgaaat ggtggaggct
     5881 catgtacttt tcaataagcg cgatgtcatt tcaattgttt tctggtatta tttgggaagc
     5941 atttcttact tgtatttaaa aaaaggagaa ttaatatgaa gacagctttc attgcttgga
     6001 ctcctttaca tttgattaat atattaaatg tttatcaaaa tttttaccga gaatcaaaag
     6061 gagatttatt tatttattct gaatttgaaa acgctagaag atatagtgag cgtataaaag
     6121 aattagggct atttaatgat gttgtttttg tgaatcaccg gaaaatcggt tcttccttta
     6181 aacgtaaaat taacttgtta actaaccata atcaattttt ctcggatgat ttatccgttt
     6241 atgatgaaat ttttatacag ggggaaaatt atttcacaaa aatacttttc tccaatgttt
     6301 acaaaaaaaa tccagatgta aaactaaatt atatagaaga tggtttgggt acttatttga
     6361 agaagagtat attttcaaca agtaaaaacg ttcaaagagt ttttaaaata ttaaataaaa
     6421 atagcatctt caaaaaaaaa attgacgatt attttgtcta ttgtccggaa ttgttacttt
     6481 atgatgtaaa aaatataaaa aaaattccca aaatagatga aaacagtaaa ttgatgaaaa
     6541 acatacaatc aatctttggg atagaagaag tttttgtcgg agataaatgt atcttttttg
     6601 atcaaccttt attatctgat ggttatggca tagatgaaac agatattttc gctaaagtaa
     6661 atagtatatt ttctggaaaa aaagaaactt taattaagct tcatcctaga gcaaggacaa
     6721 atcgttatgg tgaaaaaaac atattgaatt ccagtttacc gtttgaagtc ttgctacttg
     6781 aaaatgactt ctcttcaaca cttttgatta gtcctatatc tacaatttct ttttcaccat
     6841 ctatgatgtt tgaaaagacg atcaactcta ttatgttggc taaattaatt ttaaatgaat
     6901 atacagcatt atctgaagat aaaaaagaaa cattgacaaa tattgttctt ttctgtgaac
     6961 attataaccg tctatcagaa gaaaaaattt tactcccaga aaactgggca gaattaagaa
     7021 agttggtaga gtatgggatt atttaacaca ctttccaagt caaaattagt taagtccagt
     7081 ttctggtata ctatagggaa tttttttatt aagggaattt cattcataac tattcctatt
     7141 tttgtaaata ttactactca agcagaatat ggtttgatta ataatttcac ttcatttgta
     7201 tcaatttttt cgattcttgt tgggctaagc ctaaattcgg caattaataa tgcaagtttt
     7261 gactataaag atgacataaa tgaatttatg tcatcggtac tttctctagc tacactttcg
     7321 ttaattgtgt tcttattaat agggaacata tattttttgt tttcaaatgc tttttttgat
     7381 atgaaccaac ttgtatttaa tttgatgtta ttacaaagtt ttgctagttt tgtaattagt
     7441 tatatccagt cttattttac gattaacttt aaccatttta aatatttgat tttatctttt
     7501 atatctactt ttttgaatat tgcaatctct gtagctttga tgcagacatt atattttgat
     7561 gataaatatg ttggcagagt agtcggcgga acactgtcat ttgtgttgat aggtttagta
     7621 atttatttaa gaataatgat aaagggtgct catttttttg ataaaaaaca gtggagatac
     7681 gctttaaaaa tctctttgcc gctaatccca cattccttag caaatatagt tttagcacaa
     7741 ttcgatagaa ttatgattaa ttcttattta ggtcctgctg cggggggaat atattcctac
     7801 attagtaaca taggtattat tctaagcgta atatggatgt ctactaataa cgcctgggtt
     7861 ccatggttct atggtgagat gagtaaaaat aatgaaaaaa aagtgaagaa agttagtaac
     7921 tattatttag tagtctttac tttgattacg atgattgtaa tggtagtttc gattgattta
     7981 gcaaaattta tggctccgaa agactattat tctgggttat ctttagtggt tccgataacc
     8041 ttaggctatt tctttcagtt tttatatagt ttaccagtta atgctgaatt ttatgagaaa
     8101 aaaacatcgt ttattacgat tggtacagta gcaagtgcta tagttaatat actattaaac
     8161 atgattttca tacctaggtt aggaataatt gctgctggat acacaaccgt atttacgtat
     8221 tttttacttt ttatttttca ttataatatc gctaaaaaaa ttacgaataa acaattattt
     8281 gacacaaaaa aaatatgtat cataataatt tttgtatcaa ttttttcttt gatacttcat
     8341 attttaatca atcaaatgtt gattcgttac gttttgacat cattattgat aattagttta
     8401 gttatatatt ttttaaagat taagaatcga attatagatg actataattc ataggaggag
     8461 atataagtgt ttaaaggaaa aacaatatta gtaactggcg gaactggttc cattggaagt
     8521 gaaattgttc gtcagctttt aaaatatgaa ccaaaagcta tcagaattta tagtagaggt
     8581 gaagaaaaac aattttatat gcaacaagag ctctcaaatc acactaattt gagattttta
     8641 attggtgata tcagagactc tcaaaggatt gattatgcat gtcgtgatgt ggatattatt
     8701 tttcatgctg ccgcaatgaa acacgttcca gcaagtgaat ataatcctat ggaagctgta
     8761 aaaacaaatg tgatgggaac tcaaaatgta atagatgcag cgatcaaaaa taatgtaaaa
     8821 cattttgtag gtatcagtac agataaagta gtgagtccta ctaacaccat gggtgcgaca
     8881 aagttattga gtgaaaaatt aataatagct gccaatcagt ataaaggaaa aacagaaaca
     8941 atattttctt gtgtaaggtt tggaaatgtc atggggtcaa gtggatctgt tattcctctt
     9001 tttagtaaac aaataaaaaa caataaagat attactttga cagatgttga tatgacacga
     9061 tttatgatgt caataccgga tgctgcaaga ttagttctgt ctgctgctat gaattcaaaa
     9121 tttggagaaa catatgtctt aaaaatgccg gcaatcaata ttttaacttt agctcaatca
     9181 ttaataaaaa tatataatga tacacatgat gaaaaatata gaggtgaaat aaaagttgta
     9241 ggtatcaggc caggagaaaa attatatgaa gagctaatga ctacagacga aattgaacgc
     9301 tcatatgaaa atgataaaat gtatatcatt ccaccacact atcatgctac tgacgaactg
     9361 tacaaagatt atgaaaaaat taaaatcact gcatactctt cagatgcaac agaattaatg
     9421 agtggacagg aatttattag aatcgcaaaa gagaataatg tcgtgacttg gtaaggagtt
     9481 ttatgatgaa atcagaagta tatgtaattg cagaaattgg tgtaaaccat aatggaagtc
     9541 tagatttagc tttagaaagt attgataaag ctaaagaatg tggagctaac gcggttaaat
     9601 ttcaaacatt taaaacgaat aagctagttt ccaaaaaggc tccaatggca aaatatcaga
     9661 aggataatct taaagaggac agttctcaat ttgaaatgct aaaaaaatta gaattatctc
     9721 aatctgattt tattagaata aaagattatt gtatacaaaa taaaattgat tttttgtcta
     9781 ctccttttga tgaagaaagt gcagactttc taaaacaaat tggtgtacaa ggatttaaaa
     9841 ttggctcagg agatttaaca aatttacctt ttcttagaaa aatagatatg tatgggttgc
     9901 cagttttatt atctacaggt atggctgata ttcatgaggt cagtgaggct gtagattgtt
     9961 tcatagatag tccagttact attttacatt gtacttcaaa ttatccggct agttctgaag
    10021 atattaattt attggcgatt aacacattaa aagaaatgtt cgggataccc gttgggtact
    10081 ccgatcattc attgggatat gatgttggta tttgtgctgt tgcgatgggt gctaaggtaa
    10141 ttgagaaaca ttttaccttg gataaggaac tacctggtcc agatcataaa gcttctttag
    10201 atcctcagga atttgcagat tttgtaaagc atattagaaa cactgaaata tttttaggtg
    10261 atggtgttaa gcgagcaatg ccttctgaac ttagtacaaa agaagtatca agaaaaagcc
    10321 tagtggtcac tgagaattta aatgtgggag atattcttac agagaaatct cttacaataa
    10381 aacgtcctgg aaatggaata gctcctaagt ttttatatca atatattggc aaaaaagtta
    10441 aaagaccaat aagtgcagat agtgttctgc ttgaggaaga tgttgaatga aaaaaatact
    10501 tatagtaagt ggaacacgag ctgattatgg aatatataaa cctgttgctg agaatttact
    10561 acaagataat tgggatgtat catttgttgt ttctggaatg catttatccc ataaatatgg
    10621 atttactaaa gaattgatct tagctgacgg atttagaatt agtggagaag ttcaaagttt
    10681 gtttttagag aacaataagg gaaacatggc tcggtctgtg gcattagaga taaatggttt
    10741 cacaaatata tttgaacaaa ctagccctga ttttgtatta ttactagggg atagaggaga
    10801 aatgttggca gctgcgatag cttgtttgta tcttggaatc aaaacagcac atattcacgg
    10861 aggcgaagtg tctggtactg tagatgaatc aataagacat gccataacga aaatagcatc
    10921 tgttcatttt gctgctacgg aaaaaagcaa agagcgttta ataaaaatgg gggaagattc
    10981 ttggagagtt tttcccgtcg gagctcctag aatagatact attttaaata atagattacc
    11041 tagttttaga gatataaaag aaaaatatca tctaaaattt gaaaagaaaa aatacgtttt
    11101 gcaagtattt catccagttg taaccgaact agaaaatata gaaaaacaaa ttttagcttt
    11161 gatcaattca atggaacaac aatctcaacc aattatttgc attttaccta atagtgatgc
    11221 tggtagcgaa attatcagaa aaatgtacca gaaatattta aaaacggata ttatttatat
    11281 tacgaattta gagccggagg aatacctgac tatattaaaa gagtgcaaat ttatgatcgg
    11341 aaattcttct tctgggataa ttgaagctgc atcattcaaa ataccagtaa taaatttagg
    11401 aaccagacaa aatggacgag aacaatctaa aaatattata aatgcaaatc taaatgaaaa
    11461 tgaaattgaa actgctttga ataaaataca agatcctcag tttataaaaa gcttgaaaaa
    11521 tgttaagaac atctacggtg acggcaacag ttctagaaga ataacaaaaa cattgaatca
    11581 aatattgaat gatggggaag atattaagtg gattcaaaaa caaatagctt attaaaatat
    11641 actagtgatc catacattat tattggggct ggcggacacg caaaagtcat tattgaaacc
    11701 ttaagattag aaaataagtt aatatatgga ttttttgatg ataagcaaaa taaaatgcaa
    11761 gatctgaaat atcttgggaa aataaacgaa ttgaatagct gggcggatag caaaaaaaaa
    11821 atctataaat ttattgtagc tattggtgac tgtgtagtaa gaaaaaagat tataaaaaaa
    11881 ttgaatatgc caagtgagca atatggaata gctgttcatc caagtgctat agtggcaaaa
    11941 gaaatttcaa ttggttatgg aactgttatt tttgcgaatg ctgtaattaa cccagatgct
    12001 gtaattggag agcatgctat aataaacaca ggtagcattg ttgagcatga ttgtagaatt
    12061 aataactatg ttcatttatc tccaggtgta tgcttagcgg gtggagtaca tgtaggtgta
    12121 ggaactcaaa taggaattgg ttctcaatgt atccagatga agaaaattgg atcttggtgt
    12181 atgataggcg cagggagcac tattgttaag gatattccct cacattcctt agcttatggc
    12241 aatccagcta aaattaagaa agaaggaatt aattttgaat tctagaattt tattatcaag
    12301 tcctcatatg ggaggaacag aagaaaaata tgttgctaag gcttttaaag ataattggat
    12361 agcgccatta ggtgaaaatg tggataaatt tgaagaaagt attacaaaat atactggttc
    12421 taagggcgga gcttctgcgt taagttcagg tacagctgcc atacatcttg ccttaagact
    12481 gcttaatgtt ggaaaaaacg atattgtctt tgctccttca tttactttta tagctacagt
    12541 aaatcctatt ttatatcaag gggctgtacc agtgttcatt gactcagaac ctaatacatg
    12601 gaatatgagc cctgttgcac tagagagcgc attagaagaa gctgaaagaa acaaccaatt
    12661 acctaaggca atcatcgtag tgaatttata tggtcaaatg gctgattatg aacgaatttt
    12721 agctattgca aaccaattta atgttccagt gatagaagat gcagcggaat cgttaggttc
    12781 tacttataag ggaatttcgt caggcttatt tgggacaatt gggatctatt catttaacgg
    12841 taataagatc atcacaacct caggtggagg agctctagtg tctagtgata aaaaatatgt
    12901 tgagcattca agatttttag caacacaagc aagagatcaa gcaccgtatt atcaacatag
    12961 cgaaataggt tataattacc gtctaagcaa tatttctgcc ggtatcggac gtggacaaat
    13021 ggaagtattg aatgatagag tagctaaacg aagagaaatt ttcaatcgat ataaggaagc
    13081 tttttctgga attgatagaa ttgaaatgat gccagaagtg gatggcatgg tgccaaatcg
    13141 ttggttgtct actttaacga tcaatgatta taattctatt gatcaagtag ttaacgtaat
    13201 aaataaacta aatgaaaaaa acattgaaac aagagctttg tggaaaccac tacatttgca
    13261 accagtattt caaggggtaa aaatgtatta ccatgataat aatcttagtg tgtcagaaaa
    13321 gttatttaat agcggcttat gcttaccttc tggaagtaat atgacagata gtgaacaaga
    13381 atttgttatt gatgagttta aaaaaatatt caagtaggtg tgatatttta tgaacatagg
    13441 aattattggt ttaggttcca tggggaaaag aagacttaga ctcattcaag aacactttaa
    13501 tgatatttta ctatgtggtg ttgatactaa tgaggcgaga cgaaaggaag ttgaaaagga
    13561 atttggaata ccaacttata atagtctaac agaggcaaaa aatttgtttg aaataaattc
    13621 agtttttgtt tgtacatccc ctataaccca tgaatttatt ataaaagagg ctttaaattt
    13681 agattgtaat atctttacgg aaatcaattt attaaatgaa tattatgatg aaataatcga
    13741 agtagctaaa aagaaagata gattacttta tctatcttct acatttttga agagaaaaga
    13801 aattcaatat attaagtcta aagtgacgca taataaaaaa atttcttatc aataccatgt
    13861 aggacagtat ttacccgact ggcatccttg ggaagattat cgcaattttt ttgtttcaaa
    13921 caaaaaaact aatgggtgta gagaaatatt cgctattgaa ttaccttgga ttatagatac
    13981 atttgggaaa gttaaatcgt ttactgtaat gacccagaaa ttatccaatc ttgatattga
    14041 ttattcggac agtttcactc ttattattga gcatgaaact ggtatagttg gaactttaag
    14101 tgtagatgtt gtttcaagag tagctaaaag aaatttaact ataattggtg aaaagatttt
    14161 aatagaatgg gaaggtaacc cggattctct attttcatgg aatgaagaaa cttctagtat
    14221 gacagatatt caattgtacg atgaggttat gcatgataat aattattcac atactattat
    14281 tgaagatgca tatttagagg agattaaaga atttttcacg cttttggaaa agaaaatgga
    14341 accccaatat acttttgaaa aagataagta tattattaac ttaattaacg acattgaggt
    14401 aaattaatga tgaaagtaat tttttttggg ttagggtcaa ttggaaagag acatctaaaa
    14461 aatctaataa gctatggaaa aaagaattct attaattttg atataacagc ttatagtagc
    14521 agtggaaaaa aagagtttga agaaataacg tatattcaaa atagagacga tttggataca
    14581 cattatgata tagcttttat tacaaatccg acttttaagc atctggaaac actaaatgta
    14641 attgttgaaa aagttgatta catattttta gaaaaacctg ctttttctga gagtattgat
    14701 cttactcaat ataattatga ttacaaaaat atttatgttg ctgctccact gaggtataaa
    14761 aatatcatgg aagttgttcg taatagtatt caaagtaaaa aagtatattc tgtaagagct
    14821 atttgttcta cttatcttcc tgattggaga aaaggtactg attatagaaa taattattct
    14881 gcctttaaat ctatgggggg aggagtagaa ttagactgta tacatgaatt ggattatatt
    14941 ataaacctat ttggtttccc taaatcagta aaaaaacagt ttggtaaata ttcgaatctt
    15001 gaaattaaca gtaatgattt agcaacatat atattgagat acgatgataa aattatagaa
    15061 attcatttag attattttgg aagagttcct acaagaaaat ttcaattgtt tactttagat
    15121 gaatgtatca atgttgactt attaaataat aaaataagtt ttgaagaaaa cattgttaaa
    15181 gaaatgcctg aatctgctaa tgatatgtat gagaaggagt tgaaatattt ctttgaaaac
    15241 gtagtaacag gcaaagaaaa ctggaatgat ttatatcatg caaacgaagt attgaaaata
    15301 gctgaggaga aataaatgga aattttattt actatttgtg gtagagctgg gtctaagggg
    15361 tttaaaaata aaaatttgaa atatttggca ggaaagcccc tagtccattt cgctttagca
    15421 atgatagata tctatcaaca aaaacatcct gaacataatt gcacgacttg tttgaatacg
    15481 gacagtaatg agttagtaga attgacgact aagttaaatc cgtctgtgaa aattgtagaa
    15541 cgtaaacctg aattagctac agatactgta gggaaaattg aagtgatacg tgattcattc
    15601 ttacaactag aaagagaaga taatatattt gatttaatta tagatttaga tttgacttca
    15661 cctttacgtg aagtttctaa tcttgaagaa ttaatagatg aacatctaaa aaatttagat
    15721 aaagacgtct acttttcagt tgtttctgca agacgtaatc cctattttaa tatggtaaaa
    15781 agaattgaaa atgaagttac tatagttaat aaatcaagat acacatctag gcaacagaca
    15841 cctgaagttt ttgaaatgaa tgcctcaatg tattctttta aacctgaatt tctaaaaaaa
    15901 agtaattata tttttgatgg gcaatgtggg ataataaaaa tgagagatta tctaatttta
    15961 gatattgata gtgaagaaga ttttaaatgg ttagaatttt tgtttcctaa atttttagaa
    16021 gattcttcgg agcttcaaga tatctataat tatttatatc ggaggtaaaa ggatgagctg
    16081 ttatcttatc accggtgggg ctggcttcat tggttctacc ttagccaatc atttaggaga
    16141 agaacatgtg gtaatcgtcg tcgatgactt atcaatggga aaagtagaaa atcttgatat
    16201 gacgaaaaat atcactttta ttgagggaga tgtcgctgag aaatccttga tggaagagat
    16261 catgaaagct aataaatttg attatatctt tcatttagca gcagttgcta gtgtggcaga
    16321 ttcagttgcc cgaccagtag aaacacatcg tgtgaatttt gaaagtgtat taatgatttt
    16381 agaattgatc cgcaagtatc aacctgattt aaaacggatc gtgtttagtt cttcagcggc
    16441 tgtttatggg gatgaaccga ctttaccaaa aaaagaagag tccgtgattc gcccattgac
    16501 gccttatgcg gttgataaat tcgctgcaga acaatatgtg ctagattatt gtcatttata
    16561 tgatgtaccc ggtagcgcag ttcgtttttt caatgtctat ggtccaaatc aaaatccgaa
    16621 ttctccatac agtggtgtga tttctattct cgtagatcgc tataagaaac aaatcgtagg
    16681 agaagcaact tcatttacat tatttggtga tggaagccag tctagagact ttgtttatat
    16741 agatgatgta atccaagcat tacttttagt tgcgaatgag gaagctgcac tggggaaaca
    16801 attcaatgtt ggaacgggta aagcaaccac acttttggaa ttgattcatg caatcaatga
    16861 aattctcggt gtagaattga cacttgaata caaagaagag cgttcgggtg atatccatga
    16921 ctctctagca gatattacta agatccagtc aattggctat caaccgaaat atggtatttt
    16981 aagtggaatg actaattatt tgaaaactga aatcaattaa aacatactaa gataagatta
    17041 gagggtaaat tcaggctctt tgtcaataag gactgatgag ttttgtaaaa tcaaatctgg
    17101 gatagaaggg ctctttgtca ataaggactg atgagttttg taaaatcaaa tctgggatag
    17161 aa
//
LOCUS       DAFEEZ010000060        17005 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000060
VERSION     DAFEEZ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.063"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..124)
                     /locus_tag="LP245_002164"
     CDS             complement(<1..124)
                     /locus_tag="LP245_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HBL1520059.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVF"
     gene            complement(228..539)
                     /locus_tag="LP245_002165"
     CDS             complement(228..539)
                     /locus_tag="LP245_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL1520060.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(541..738)
                     /locus_tag="LP245_002166"
     CDS             complement(541..738)
                     /locus_tag="LP245_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBL1520061.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1132..2859)
                     /locus_tag="LP245_002167"
     CDS             complement(1132..2859)
                     /locus_tag="LP245_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBL1520062.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2852..4045)
                     /locus_tag="LP245_002168"
     CDS             complement(2852..4045)
                     /locus_tag="LP245_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL1520063.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4232..4876)
                     /locus_tag="LP245_002169"
     CDS             complement(4232..4876)
                     /locus_tag="LP245_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1520064.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4970..5104)
                     /locus_tag="LP245_002170"
     CDS             complement(4970..5104)
                     /locus_tag="LP245_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBL1520065.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="LP245_002171"
     CDS             complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="LP245_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBL1520066.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7235..7708)
                     /locus_tag="LP245_002172"
     CDS             complement(7235..7708)
                     /locus_tag="LP245_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBL1520067.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8109..8333
                     /gene="nrdH"
                     /locus_tag="LP245_002173"
     CDS             8109..8333
                     /gene="nrdH"
                     /locus_tag="LP245_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBL1520068.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8492..10651
                     /gene="nrdE"
                     /locus_tag="LP245_002174"
     CDS             8492..10651
                     /gene="nrdE"
                     /locus_tag="LP245_002174"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBL1520069.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNSLYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10701..11666
                     /gene="nrdF"
                     /locus_tag="LP245_002175"
     CDS             10701..11666
                     /gene="nrdF"
                     /locus_tag="LP245_002175"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBL1520070.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11755..12894)
                     /locus_tag="LP245_002176"
     CDS             complement(11755..12894)
                     /locus_tag="LP245_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1520071.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13203..13916)
                     /locus_tag="LP245_002177"
     CDS             complement(13203..13916)
                     /locus_tag="LP245_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBL1520072.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="LP245_002178"
     CDS             complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="LP245_002178"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBL1520073.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15105..16637
                     /locus_tag="LP245_002179"
     CDS             15105..16637
                     /locus_tag="LP245_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL1520074.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16828..>17005)
                     /locus_tag="LP245_002180"
     CDS             complement(16828..>17005)
                     /locus_tag="LP245_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1520075.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2908 g         5324 t
ORIGIN      
        1 aaaaaacaca ttccactaaa tttgatgccg gttttccttg aggttttgtt ccagcacctc
       61 ctttaatttt tttaagctct tgatctgaac attgtttagc atttagtcta tttttttctt
      121 ccattacgat tccccctaca aactataaat acttttatgt cactgattca atatacctat
      181 ttttctaatc aaaaaatttt gagacatatt taatattata agtatcatta aaattgagat
      241 ttatctccat aatctgctcg atataaacca tttattccag cagttcttcc aatttcactc
      301 aaatttctta ttaattcctc ttgatattca gtgaatctta ttttattagt ataagcagta
      361 aaatatagat aattcaccaa tctatttatt aaaggactgg gatctaattc atatttttgt
      421 ttttctaatt ttaaatatac cttttgtaaa acctcaagaa tatcagaata tttaggatct
      481 ttacttatag atatatcatt atataattca tgaacaattt gcttagcatt ttttttcatt
      541 ttagcacttc cctggaattg ctccacctaa aaaaccacct atagacattc ctgcaataca
      601 agtagttgcc ttggcccaat cgaccgtaca tttattttta gtgcaataca ctccatttcc
      661 ataatatttt ccactatgag tggtaccccc atagataagt tgtgtctctt taatagacaa
      721 aatttttaaa tgtttcataa tctaatcacc cctaaattaa tgtttttaga ctattattct
      781 aacattcatt aaatttcaaa aaacaattcc ttcttgaaac gtagcaaaat aattcctgaa
      841 taagaattta atcactttta agtatataaa ctatgtatat tctttaatat tttttgagaa
      901 tgcacttcgt acataataaa ctttaatcac attagtcttt catacctacg atcgatctct
      961 ttgactcgca cccataaatt cataatagtt tgtcggcgtc tttgaacgtt tcgaagatga
     1021 gctacgcatt ctcttttttt atagacaaaa aagatagaga cgaacatgga gcttccaaat
     1081 ttggatattt gatccaattt tggaagctcc atttatttcg tgtctgtctt tttatttttt
     1141 ccagctttcg actaattctt ggttctcttt gatccagtct tttgctgctt gctgtggatc
     1201 ttttccattg ttgatttcca acataacttt ttccatatct ttttctgacc aatggaaatt
     1261 gtctaatact ttgtaagctt ctggctggtc ttctttcaat ccttttcgaa ccatcgtatg
     1321 gatctgctct tcgcttccca ttccgttttc aggatcttct aagtatttca gatcatattt
     1381 ggcaaacatc caatgaggtg tccatcctgt aactacaatt ggttcgtgtt ttttgatcgc
     1441 ttgacctagt gcaacggtca ttgctcctga agaagatgtc tctactttcc agtctttcaa
     1501 gttgtcatat ttttggatcg tgttttcagc agccgtaact acaccagctc ctggctcgat
     1561 tcctatgatt ttcttacctg cctgatcggt taactcatcg atcgaattta catccatgta
     1621 ggctggcact gctaaaccaa cttttgctcc tgtcaaattg gcacctaggt cttcgacttg
     1681 atctttatat tgtgcatatt gtgaaccatg agttttaggt agccaagctg aaaccatggc
     1741 atctgactcg ccatttgaaa cagatttcca catgattgaa ttatctaatg gcgtcatcgt
     1801 tacatcatag cccatttgtt tcaatacttc accgactaca tttgttgaag caacttctgt
     1861 atcccattca acataagata agttgatacg ttttgtttct ttggcagatg aaaaactccc
     1921 tataccaatc gcacctaaga tcactactac tacagcacca atgatcagtc cttgacgttt
     1981 tttacttttc tgtgttgttg ctcctgcagc ttttttattg tttggctggt tcaaatgctg
     2041 tgtaaaacgg tcaatgatga ttgctaagat aactaatgca accccgttga caaatccatt
     2101 cccgacttgt gctctttgca atgctgataa tacgccgcgt cctaagccgg gtgcaccgat
     2161 catagaggca ataacgacca ttgaaagtga cagcattgtt gtttgattga tccctgccat
     2221 gatcgtactt ttagctaaag gcaattctag tttgaatagt ttttgacgac ttgtgctccc
     2281 gaatgaatca gaagcttcta ctaattcttt aggaacttgt cgaatcccta aattcgtaaa
     2341 acgaacggtt ggtggcagag caaagatgac tgaggcaaat acccctggaa ccatcccgat
     2401 accgaaaaat gcaactgctg gaatcaaata aacgaatcct ggcattgtct gcataaagtc
     2461 aaggatcggt ttgataatac tttgggcttt actgcttttt gccatcaaga tccctaatgg
     2521 taccccaatg atgatcgaga tcacactaga taaaagaaca agtgtgacag tattcatcaa
     2581 atcattccat agaccttggt tataaataaa ccatagaccg attaatgtga acaacgtaag
     2641 tcctggacgt ttcttagaaa taaagaaagc tgctaccgtc aataacaaga taaacaaagg
     2701 agctggaatc actaacagta aatttgtaat ccccgacatc actgcctgtc caatcgtttg
     2761 taaaaatgaa aataggccag aaaaagttgt cgtaaaccat tctgtgatat tttctaccca
     2821 gtttgccact ggtaattgat agttcaatag attattcatg ttcactcacc tcgcttgttt
     2881 ctgctaatgc ttcaatcaca ctacctcgga tgacgacacc ttttaatttt ccatcctcta
     2941 caactgcaag tggagtcggt gagtcataaa taatattgaa aatatcactt accaccatgt
     3001 ctttcccaat caccgtcaca ttttcatcta ggaagtcgat caatggacgt ttttgcttcc
     3061 tagcttctaa cgcttgatct gcagtgatga tccctttcag gtgtctcttt ctgtcaacag
     3121 ccatcagcat gctgacttct tcattacgca tccttgtcaa tgcaacgttt ggtccatcag
     3181 attcgatatt cgtcgtcaat gcaggtacca tgatgttttg agccgtaagc actttggaac
     3241 gatcgacttc ttccacaaat tcacgtacat aatcatttgc tggattggtc aatatttctt
     3301 cacctgttcc gatctgcatg atttcgccgt ctttcatcaa ggcgattctg tccccaatcc
     3361 gtaaagcttc attcaaatca tgggtaatga aaataatcgt tttttgaaca ttggcttgca
     3421 ggtccagtaa ttcgtcttgc atttctcgcc ggatcagcgg atcaagagcc gagaacgctt
     3481 cgtccatcag caagatctca ggatcatttg ctaaagctct ggctaggcca acccgttgtt
     3541 gcatcccacc agataactga ctaggatatt ggtctttaaa tgaaagcaaa ctagaatttt
     3601 ctaatgcttt ttctgctttt tcttgtcgtt cttctttagg tacaccacgg acttctaacc
     3661 cgtattctgt attttccaag atcgttcgat gtggaaacag accgaagttt tggaaaacca
     3721 tattgatttt atgacgacgg acttctcgca attcttcttt gcttaacttc gatacatctt
     3781 ctccatcaat atagatactg cccgaagttg gctcaatcag acgattcaat agacggatca
     3841 atgtggattt cccactcccg gaaagcccca tgatcacgaa gatttctcct tcttttacgt
     3901 caaaattcac gtcatacaca ccaaccgttg caccggtttt ctttaaaatc tccgttttcg
     3961 gctggtgatc attcatcata tctaaagcgg cttgtgtctt tttaccaaat atctttgtta
     4021 aatgttttac ttctactttt accaaacaaa ttctcctttt ttatgtaaat tcatttttct
     4081 ttctgaaaaa agtgaccaca ctatgttaac atcatgtagt cactttgtca aaaatgaaag
     4141 aaatttgctt gtccaaactg aaaaaaactt ggctaaatct ttgtaaataa aaggtttagc
     4201 caagttaata tttttttaat atttcacaca atcattctgc aagctgatgc tccgggtaaa
     4261 aaaagtttgt catacgctgt agtgtatatt catttccaat aaaatgaacg atgtcccctg
     4321 ccgtaaattt agcatagggg ccaggtgaaa caagcagttc ttcattatga gaaattgcga
     4381 taactgtggc gccagtcgcc tgccagatat tcaactcgct aattgaacgg tccagatgca
     4441 ttgctttttc tgataaagat aattcaaacg gaagtaaagg attcatctta tgtattcgct
     4501 tcgtttgatt gaccagctga tccaataatt gagaaaaatg attcagctca tcttgttgct
     4561 tctccacact tgccatgatt tctgcttttg tatcttggat ggattgtaca tcttgatatt
     4621 gcaataggaa atcttttgct ttttccttcg aagcaacaaa tgccccactt ccatgccgta
     4681 cttccatgat tccaagatct accagcacat tgatagcctt gcgggtagtc tcaggagaag
     4741 cattgtacgt actggcaagt gttgagcggg catggatctt ctcacccact ttatatcggt
     4801 tttcaacgat acgttcggct aaatcaacag caatctgctg gtagcgcggg cggacgattt
     4861 ttttctttcc agacattttc tttcctcttt ctttttttac tttccctcat cttactatgc
     4921 tctagcaaaa taagcaaaaa aggggagaat agcctcttgc aacgactgat catcgcttga
     4981 tctgttcctt ttttactggg caagctgttt gacagtcatc acaattctta ccggatttta
     5041 aacgagtata gacaattgcg cctgcacttc caaagattaa cacacttaat aagaatgtcg
     5101 ccatcctatt cctctccttc taatgacaat atagtataaa actggttctt ggattttggc
     5161 tgacggaaca aaacataaac gagtcctatc atcagtaaaa tagcaagata cgtccctaac
     5221 gctacctgtc caccctccaa taagtgtccc aactgataaa tcacaaaact aactaaataa
     5281 gctaaaccgc attgatagcc tatggcgatc caagtccatt tcttggcatt catttcccga
     5341 tggatagccc caattgccgc aaaacaaggc gcacaaagta aattgaaggc taacaatgaa
     5401 taagctgctg cgggagtata tgtgtgttgt agcacttgcc agatttctct gccattttcg
     5461 gatacttccg catgaccaaa caaaatacca aatgtgccaa taatattttc tttagcgacc
     5521 aatcctgtaa tcgctgcgac tgttccttgc cagtttcccc aaccaagcgg ctgaaaaaca
     5581 actgccagga ttcgcccgaa aaaggctaag atactttggt cttcagaaac aggttgagca
     5641 taaaaattat aagaagagct gaaccagatc acgatactag aaacaaagat aatcgttcct
     5701 gcttttttaa caaaagactt gctgcggtca taggtttgtc ttaggaccgc tgaccattga
     5761 ggaaaatgat atgcgggcaa ttccatgata aaaggagctg tatctccagc aaacaaacgt
     5821 gtttttttca agctgattcc agagaaaata attgcagtca taccaagaaa ataggcagaa
     5881 ggagctaccc aagattgatg aggaaaaaag gcccctgcta ctaaggcaat aatcggcaac
     5941 tttgcagaac aaggcatgaa ggttgtgacc atgatcgtca aacgacgatc ttgctcgttt
     6001 tcaatcgtgc gactggccat gacgcctggc actccacatc ctgtagcaat cagcatagga
     6061 atgaaggatt ttcctgaaag accgaatttc ctgaaaagtc gatccatgac aaaagcgatc
     6121 ctcgccatat atccgcagtc ttccagaaag ctcaagcata aaaacaatat aatcaattgc
     6181 ggtagaaatc ctaacactgc tcccacgcct gcgatgatgc cgttcaagat cagctcctgc
     6241 atccatcccg ctacttgcca ttcagctaac aatctgccaa catgttctgg taaccatgta
     6301 ccaaacaatg tgtcattgat ccaatctgtc cccattgttc ctactgtttg aatagccaga
     6361 taatagatca gccacatcac aaatgcgaag atcggcaagg ctaaccaacg attcgttgca
     6421 atctgatcga ttttgtcact catcgataat tggaaagaat catttgacac aacacagagt
     6481 gtacatagtt gggtaataaa ttcataacgt tcattgacca gaatcgtctc actatcgtcg
     6541 tccaatagtt tctctgttaa ctggatcagt tgctcgatct ctttttgctg agaaactgct
     6601 atctcgtaat cctctcttac cttctgatct cgttcaaaat atttcattgc ataccagcgt
     6661 ttcttgccgc tttgttctcc tagtacatct tcaatttcat gtaaagctgc ttctaaacgt
     6721 ggatcatatg tacagggaac aggaatagaa ggccgctttt ttgcagactc ctgaatcttt
     6781 tcgattagtt tttcgattcc ttgctttttc aatacgctga ttggtaaaac tggtacacca
     6841 agaccatagg aaagcttttc tagattgatt ttttttcctt cttttttgat gacatccatc
     6901 atattcagac caatgatcat aggaatgtct aaatccaata actgcgtagt taaataaaga
     6961 tttcgttcta aattggtagc atcaataatg ttgatgatca gttcaggctg ttcctgaacc
     7021 aaataatctc ttgcaatcac ttcttctggt gtataaggag acaaagaata gatgccgggt
     7081 aggtcctgaa tatgaatgtt cggatttttt ttcaacgatc cttctttttt ttctactgtt
     7141 acgcccggcc aattccctac atattgattc gaaccagtca agagattgaa caagctagtt
     7201 ttcccgctgt ttggatttcc gactaacgcg atattcattc tttttcctcc ctttgtatca
     7261 agattagttc ggcctctgac tttcgtaacg tcagttcata ccctcgcact gtcagttcga
     7321 ttggatctcc cagaggggct agttttcgga taactatttt tacatttcgc gtcaatccca
     7381 tatccattaa ccgtcgcttc actgcgcctt gtccgtggat tgctacgacg atcccagtct
     7441 ctcctgcttt taattgatca agagaagtcc agctttcaga ggaagcagtc tttttattga
     7501 caaagatttg acctagtatt tcccgactta ctgccactcg atgacttttt accagtaaaa
     7561 tggcattgtt gcctgataaa ttgacgacga cgattttact tccggcaacg atcccgatat
     7621 tttgcaaatg gcgttttgtt ttttcttctg tttcgattcg ttcgacttga taaacgaaat
     7681 tctgctttgc ctgcgctaag gtctgcatat tgattcctct cttgtgaaat aaatcatgta
     7741 ttaaaatcat tcattatatg ttctaatttt cttacgtgtt acgcaaataa atgagaatca
     7801 ttctcacata gaatactctc ggtaattgag aatgtcaatt atacttgtga tattatgagc
     7861 gaatctttag tattgataga taaaaatgag aaaaaaatat ttcttcatag ttttccacaa
     7921 ttttttctct attaaatttg ctattttccc acacgatact tgttttcagc tcttttttca
     7981 aaaacacaaa acttagtatt ccacagtttc cacaacacaa tatgtagtgt ttgttgtttg
     8041 acttttttac taagagtttt atactatcta ttatagataa taagaatgtg ttagaggagg
     8101 cactcaccat gaacgtaaaa atcttttcta aaaataattg tatgcaatgt aagatggtca
     8161 aacggttttt aacagaaaat caaattgctt ttgaagaagt caatatcgat gaacagcctg
     8221 aagcagtaga ctggttgaaa gcacaaggat tccaaagtgt tcctgtcatt acttctgatg
     8281 cagaaacagt tatcggattc cgtcctgatc agttgcgtaa acttgccagc taacatgact
     8341 aaaagaatca aaacgtgata catggatttg aagggcttga gacagcacca gtttttgtcg
     8401 caaacttcca aatccttttt taaagcttaa aaacaatgca atgatttgca atcaagcatc
     8461 atcaaatacg aaatgaaggt tgggcgtacg tatgagtctt aaaaatttac aagatgtcag
     8521 ttatttcaag ctgaataatg aaatcaatcg gccagtcaat ggtcaaatcc ctttgaataa
     8581 ggataaagaa gctttagttg ccttttttga ggaaaatgtc aaaccaaata cgatgacttt
     8641 tccatctatt atggaaaaaa tcaattactt gatcgatcaa gaatatatag aagcagaatt
     8701 cattcaattg tattcaccat catttattga aaagctatat caatttttgg acgagcaaca
     8761 tttttctttc aaatctttta tggctgctta caaattttat tctcaatatg cgttgaaaac
     8821 caacgacggt tccgcttatc tggaaactta tgaagatcga gtagccttca attcgcttta
     8881 ctttgcgaac ggggatgaag aattagcact tgctcttgca gacgaaatga tccatcaacg
     8941 atatcagcca gctacacctt ctttcttgaa tgctggacgt aaacgtcggg gcgaattggt
     9001 gtcttgtttc ttgactcaag tcactgacga tatgaactct atcgggcgct caatcaactc
     9061 tgctttgcaa ttgtcccgta ttggtggcgg cgtagggatt actttatcaa atcttcgtga
     9121 agccggcgct cctatcaaag gatatgaggg tgctgcaagt ggtgtcgttc cagtcatgaa
     9181 attattcgaa gatagtttca gctattctaa tcaattaggt cagcgtcaag gagctggcgt
     9241 ggtttatttg aacgttttcc atccagacat tattgctttc ctttcagcaa aaaaagaaaa
     9301 tgcagatgaa aagattcgcg taaaaactct ttctcttggc gtgatcgtac ctgataaatt
     9361 ttatgaattg acacgtaaaa acgaagatat gtatttattt agtccatata gtgtcgaaaa
     9421 agaatatggt gtcccattct cttatgtaaa tattacagct gagtatgatc atctagttgc
     9481 aaatccaaac attcgcaaac aaaaaatcaa agcgcgtgat cttgaaaatg aaatctcaaa
     9541 attacaacaa gaatctggct atccttacgt aatcaatatt gatacagcga accgcgagaa
     9601 tccaatcgat ggcaagatca tcatgagtaa tttatgttca gagattttac aagttcaaac
     9661 gccttctgtg attaacggca aacaggaata tgaagtatta ggaacagata tctcatgtaa
     9721 cttaggctcg acaaatatcg tgaatttgat gcaaagccct aactttggtc aatctgtgcg
     9781 tacgatgact cgtgcattga catttattac agatgcatct gatatcgatg tcgtaccacc
     9841 gatccaaaac ggaaataagc tgaatcatac gattggatta ggtgccatgg gcttacacac
     9901 ttatcttgca aaagaacaaa tggaatatgg ctcagaggat tcattagact ttacaaatat
     9961 ttacttcatg ctgttgaatt attggacact tgttgaaagc aacaatatcg ctcgtgaaag
    10021 aaaacaagtt ttccataatt ttgaaaaatc agcttatgct gacggcactt atttcgaaaa
    10081 atacgtaact ggagaattcc agccaaaatc agaaaaagtc aaagcattgt ttgaaggcat
    10141 ttttatccca actgctgaag attggaatgc tttgaaacaa gcagtaatga aagatggact
    10201 gtatcatcaa aatcgcttgg cagtagcacc aaatggctca atttcatata tcaacgatac
    10261 gagtgcaagt attcatccta tcactcgcat gatcgaagaa cgccaagaga agaaaatcgg
    10321 taaaatttat tacccagcgc cttatctatc caatgagacg attccgtatt acacttctgc
    10381 ttatgatatg gacatgcgta aagtaatcga tgtttatgca acggcacaac aacacgtcga
    10441 tcaaggcatg agtttgactt tattcatgcg ttctgaaatc ccagaaggca tttatgaatg
    10501 gaagacaaca acgaagcaaa cgacacgtga tttgaatatt ttaagacatt acgctttcca
    10561 caaaggaatc aaatccattt attacgtacg tacctttact gatgatgcag aagaaatcgg
    10621 aagcaatcaa tgtgaaagct gcgtgatcta atatcataga tagattcgct tattcatatt
    10681 ttaattaaag gagcattctc atgtcagaaa catattatga agcaataaac tggaatgaaa
    10741 ttgaagatat cattgataaa tccacttggg agaagctgac agagcaattt tggctagata
    10801 cacgtatccc actttcaaat gacctagatg attggcgtac attgtctcaa ttggaaaaag
    10861 atacagtagg acatgtattt ggcggtttga cactgctaga tactgtccaa tctgaaagtg
    10921 gcatggatca gttgcgtaaa gatgtccgca ctccccatga agaagccgtt ttgaacaata
    10981 ttcaattcat ggaatccgtt catgccaaaa gttattcttc tatttttagt acactgaata
    11041 cgaaaaaaga aatcgaagaa atttttgact ggacaaatac gaatccttat ctgcaaaaaa
    11101 aagctgagcg tatcaatgaa atctacaaac acggtacacc gctagaaaag aaaattgcca
    11161 gcgtcttttt agaaacattc ttgttctatt caggttttta tactcctctt tattatttag
    11221 gaaacaacaa attggctaac gtagcagaga tcatcaaact aatcatccga gatgaatctg
    11281 tacatggaac ctacatcggt tacaaattcc aattaggatt caacgagtta cctgaagcag
    11341 aacaagaaac gttaaaagac tggatgtaca atcttcttta tgagctttac gaaaacgaag
    11401 aacgttatac agaagaatta tacgatccaa tcggctggac agaagaagtc aagacattcc
    11461 tacgctataa tgccaacaaa gcattgatga acctagggat ggatccactc tttccagata
    11521 ctgccaatga tgtcaaccca atcgtaatga acgggatttc aacaggcaca agcaaccatg
    11581 acttcttctc acaagtcgga aacggctatt tgttaggtca tgtagaagcg atgaaagacg
    11641 acgattattt gattggattg gaataaggat ttattttaat tcaaaaattt ttcgaaaaat
    11701 aaaaagagtt tagcgtacag atattttaaa tgtacactga actctttttt atgcttattc
    11761 acttgtttct tccagcactt ttggactgtc taacttttcc gaaacatgtt ccattcttct
    11821 caataaatag attttccgga tatttaatat tatcgtctta atcactgcat agacaggtat
    11881 gcaaatcagc atgcctaata ttcctgcgac acttcctgct ccaatcaata ccaagatgat
    11941 cgtcaaagga tggatattca ttgatttccc aaataacaac ggcttgatca aatttccatc
    12001 taattgttgg atcactaaaa tcgacaacgc catatacaaa gcttgaaatg gagagataaa
    12061 caaaccgaca atgattgctg gtaccgctcc aataaaaggg ccgacatacg ggataatatt
    12121 cgtgattccg caaatgaccg caagcaacaa gctataaggc tgatcgaata ttctcattgc
    12181 caaaaagctc attacaccaa taatcaaagc atctaagatc gtactgctga tataggcaga
    12241 taatgtttcg tttaattctt ttaccgtttg gcgtaactct ttacgaatcg ctttcggaaa
    12301 gaagtgagac aacgcatcaa taaatttgtg cccatccttg aacataaata gcaaaataaa
    12361 tggaacggta aataacaaaa taaaaaattg catcataaat gaaatgattt ttgagacact
    12421 tgcagataaa ctgactaata tgatattgaa caaattacta agagataaat ttgctgatgc
    12481 taattgttct tccaaattga aatttttaaa ctcttcccgc tgcgccaatt catttaacca
    12541 tttgcttgtt tcatctgcat acattggcaa gctctgggtc aattgaattg tctgttccat
    12601 taactgaggc actacattca tgacagttaa aacaactaaa atgattacga ccaaaaacgt
    12661 caataaaaaa ccgaacactc tcgggatccg atgcttttcg agaaaaacaa cgattggatc
    12721 gaacatataa tagataaaac cagcaacaag caatggtaaa aaaattgccg aaagcatttt
    12781 caatattgga ctaaaaatat tcggcatttg taaaataaag tacacgccga tgatcgtgag
    12841 tactagctcc actgtccaga aaaataattt tgattgttta aaacgtgatt gcatacatct
    12901 cctccaaggt cctttgatac ttctattcta tcatttaaca aagagttacg cgctgagatt
    12961 ttcatttgct taaaaaaaac aaaaaaaata aacatatttt aatgagtaga cgagtactta
    13021 aacaaaaaca cggtttggag tagtgacaaa aattatactg cagtcccttt ttccaaataa
    13081 acggtgttca aaagcttgca tcttcgtaat aagcccagcc aaacgaaaaa tataaggaac
    13141 tatttttatt tggctgggct tattacttga tgtaggacat ctattttaca acctcagatc
    13201 atttattgcg caatactgac taaatgcaac tttgtgatat ttttgtgtac ggacaactcc
    13261 tcgatcacat cggcataagt gagccctttt ggaagatcaa tcgtatagat atttttgtac
    13321 actcggtagt catcaacgaa ttttacgtca aaattcacat cttcgattac gatatttttc
    13381 tcttcaaaat aatcggtaag aaaatctttg gtttcttttc tatggataaa ttggatttct
    13441 aactttttag tcgtaggtac atggatcacg cgtttcacta ctgtgagtgc aatagcaatc
    13501 ccgataaaac tgatgatcgc aatggaatag taacccatgc cgatggcgat ccctaatcca
    13561 gcaattgccc ataaagaagc ggcagtcgta agtcccgtca ccgattgttt cgtgacgatg
    13621 atcgttcccg cgcctaagaa accgacacca ctcaccactt gagcaatcag ccttgcttca
    13681 tctgaacgaa tcgttccagc aagctgtgga tactctaaag catctcttaa tgcaccacta
    13741 gcgatctcaa cttggatcaa tgcaatgata catgctccca tacaaactaa aatatgcgta
    13801 cgcatacctg ctggacgatt tttatattgt cgttcaaaac cgattgctcc gccaaatagc
    13861 atagcgatcc ctaaacgtaa aataatctct ggaattgtca ataccatatc attcatctaa
    13921 acaccctcca gtccaatata tcatgtctga aaggagcaga caaaaaaagt gcaattttta
    13981 cctcttacga aaaaaggact gtgacaaaat ttttgtcata gtccttttta tgaataaacg
    14041 gtgttcaatc agctgaccct cggtattact caacaaacgg caaaatatgg ggagctattt
    14101 ttcctttgtc ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttagcctac
    14161 tattgaaaat tacaacttac ttgctgcttc ttcatcgatg atcacaacaa cattgtcgtg
    14221 attttgcaat acacttgctg gcaaatgatt cgttacaggt ccttcaatca tccctttgat
    14281 tgcatcagct ttgctttcgc caaatgccat caagacgatt tctttacttt tcataattga
    14341 accgattccc attgaaacag cttttgttgg tacatcttct gctttatcga agaatcgttt
    14401 gtttgcattg attgttgatt ctgttaagtc aactactgaa gtcgttccgt caaatgaagc
    14461 accaggttca ttgaaaccga tatgtccatt ttgcccgatt cctaagattt ggatatcgat
    14521 tggatgtgca tcgatgattt gatcatactt tttgcatgct gcttccagat cttctgcttt
    14581 tccatctggt acaaacgttt ctttgaatgg ttttttatca aataattgga catccatgaa
    14641 atgacggtag ctttgttcat ctgaaccgcc tagtccaacg tactcatcta agtttacaga
    14701 agtcatttca ctgaaatcca aatcgcttga agtcatttct ttatataaag taactggtgt
    14761 gcttcctgtt gccaatccta atacttttgc acctttgttc ataccttctt tgatgatttc
    14821 aaatgctttt tttccgcctt cttcagcgtt ttttacacga atgatttcca tagtgattgc
    14881 tcctttatat tttggtatag cccaattata gcattctttt tttcttttta caataattag
    14941 tatagaccaa attgcatttt tttcattttc ttgacaataa ataggaatcc gtgttaggtt
    15001 tcataagatg gttcaatcaa acaatccatg ttgcatgaaa accaagcaag tgattcactg
    15061 tggacgcttt atgtctgcag tttttttatg aaaaaggagt tattatgagt atactgacat
    15121 taaacaacat tacccagcaa tttggcgaca aaatcctcta tgaaggtgtc gatctgcaat
    15181 taaatgctgg cgaacatctt gggctgattg gacaaaacgg agccggtaaa agtacattga
    15241 ttaaaatcat cactggtgag atcttaccag atgacggaca gatccattgg caaaaaaata
    15301 ttcacaaagg ttacctcgat caatatgtgg aagtcgatga aacattaaca atcgaagaat
    15361 ttctaaaaac tgcgtacgca aaagaatacg aaaaggaaga aaaaattgct tttctttacc
    15421 aaacatatag cgagaccttc gatgattcct tgctggaaaa agctgggaaa ctccaaacgg
    15481 aattagacca aggagtgttt tatcaaatcg acaccttagt tgctgagatg agcagcgggt
    15541 tggggatcga tgtcttaggt ttagattcac tgttgaaaaa tctaagtggt ggacaacgtt
    15601 caaaggtgat tttagcaaaa ctacttttag aaaacccaga tgttctgatc ttagatgaac
    15661 caaccaatca cttagatgat cagcatatcc aatggctgac gcagtttctt caggattttg
    15721 acggtgcgta tatcgtgatt tcccatgacc aagaatttct tgatcagatc accacccata
    15781 tcgcagacat cgagtttgga aagattacta agtatactgg ccatctaaaa caagcattga
    15841 aacaaaagga acaaaatcgc gaaagctatt tgcgccaata tcatgctcaa caaaaacaaa
    15901 tcgaaaagac cgaagcttat attcgaaaat acaaagccgg ttcccgatca acgatggcaa
    15961 aaagccgaca aaaacaatta gataaaatcg aacggctgac gcctccagct tcagcaagta
    16021 aagctgtctt tgattttcca ttctcgccta ttgtcacgac attagcagtg gaaacaactg
    16081 atttagtcat cggatatgat cgaccgctac ttgcacccat caatttgacc atccgctttg
    16141 gtgaaaatat tgccattcga ggcttcaacg ggattggaaa atctacttta ttaaaaacac
    16201 tgatcggtga gattgaaaaa ataagtggcg atttccactt cccagataac acaaaaatca
    16261 attacttttc acaagatctg tactgggaaa atccattaga aacaccacta caatatttaa
    16321 gcagtcaatt tccaaaagcg actatcaaag aattacgtcg ccaactagct aaagcagggt
    16381 tagttaatca attagcaagt gaacctctca ctacattaag tggtggggaa caaactaagg
    16441 tgaaacttgc acagttgaca atgaaccaag gtaatttact gattctcgat gaaccgacga
    16501 accatatcga tcaagaaacg aaagaaagct tacaagacgg gatacagaaa tttccaggaa
    16561 cagtaatcat cgtctctcat gaacaagaat tttatcaaga tcttgtgcaa cgagtcattg
    16621 agattgaacc aaaataaacg tttgattgaa tagttgaaaa aaaggagctg tgacaaaagt
    16681 tttgtcacaa ctccttcttc tgaataaatg gtggccaatt agctgacctt cggtattagc
    16741 tcaaaaaacg gcaaaatatg aggagctatt tttatttggc tattcttatt acttgatgca
    16801 gaacagcttt tcacaacctc ttttcgtcta ttttttattt tcgagatttc tctttccttt
    16861 aaaaacaact gtttgaaaga agaacgcaca tccttgaaaa acaagcccgc taaccgttac
    16921 acctaaccag ccatactgct gccacattgt cgtccctagc aatgaaccag ccgcacctcc
    16981 aataaagtac ataaacataa ataca
//
LOCUS       DAFEEZ010000061        16988 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000061
VERSION     DAFEEZ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.064"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            471..695
                     /locus_tag="LP245_002181"
     CDS             471..695
                     /locus_tag="LP245_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520076.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMIREAT
                     PVEIDYCKLVYCGCGRWKEDHVQKNISKYI"
     gene            713..1141
                     /locus_tag="LP245_002182"
     CDS             713..1141
                     /locus_tag="LP245_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520077.1"
                     /translation="MEKSDTKANRYKPTAAEKKLLEVLINPDNLGKPVQELCSLAKIG
                     RTKYYDAMSKDGFVDLVNETTMDLIKGKASDVLNATYKYALTEKGHQDRKMILTIAGI
                     YADKQELKHSGGVDIRKQYEKMSDEELEELVKRYEKINDS"
     gene            1119..2537
                     /gene="terL"
                     /locus_tag="LP245_002183"
     CDS             1119..2537
                     /gene="terL"
                     /locus_tag="LP245_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HBL1520078.1"
                     /translation="MKKSTTLNRVEYAVVQRELAIRKARKSFWLFCQLLYPEFYKDDR
                     LYLKDLCHTLQDFYEDKIDKKILVINMPPRHGKTFTARLFVLWMFGQNPKTKIITGSY
                     NQILSSLFAQQTRDGIMVENENVKAEYFKDIFPEVQIKYGDAAKGFWSLDGSEEKNYL
                     ATSPGGTSTGIGANYVIVDDIIKTAEEAYNERVLDSHWEWYNNTLAQRMERPRKQILI
                     MTRWSSNDLAGKMLTRRKNNVHQICYKAVQEDGSMLCNEIMTHDEYLDVVQEMNVDIA
                     EANYQQEPIDQKGRLYQKFLTYDTLPDNIIKIWNYTDTADKGADYFASPVFAETSDHD
                     AYIIDVMYTKEPMETTEIAHANMIIRNRVNKVRIEGNNGGRGFRRNSERITKERGYRG
                     AVFEDFHQSDNKLSRILANSAWVENHVYYPDDWATRWPDFYEAMVSYQREGKNAHDDA
                     PDAVTGIAETIIEADDFEFIAY"
     gene            2549..4084
                     /locus_tag="LP245_002184"
     CDS             2549..4084
                     /locus_tag="LP245_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL1520079.1"
                     /translation="MFYSGITLKKYKRLRTKYSTQIEEGLFDPNAFMEDMKPFFDDRE
                     RKYLAYTSEKNEIDSREKPKTKIIKVNNKIHAGMYSVVVDQAVNHFTGIPIKWDYDVS
                     EQKRTFIQRMRDKLLGNDISAPSTPEEFETLTRQLSTMRFGMLDPDTATFQGATGLAF
                     RLLEPVETNDGWELRASNIEPWKAEKYENGAVYIKEKYDPYQKKFYEEMKVVTPKSIF
                     TYARYTDYPGTVQGAFKTLGNVPNPLGVINLTEFKNNTNRYCDFEVAEEISDAIDRVL
                     SDQQNEIEQFKLAYMLITGADLSEDKAKKMMEQLGIINLKDPNAKAGYVTKDLQKDFN
                     EYHFDLLKKQFYTVCKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAEVMAAYLDFAEKVTIDPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMIDVESRQSYPDGEYGGGIVESNRNEVLDQTSRTGRFSKTQNGKSNAK
                     ETK"
     gene            4164..5042
                     /locus_tag="LP245_002185"
     CDS             4164..5042
                     /locus_tag="LP245_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBL1520080.1"
                     /translation="MMEFYSTSDQKKYREYVEKNYKSLKMYDAKYKEFIEEYFPSFDY
                     AKVNRLLQMRSDIFRILAESAIDADVNKYFSDRLEDILQRSYVSNANVFAQILNVDLP
                     NYLSKEELERYLNYPWSGKTFSRRLWGNISSLEQKLSNAITTSVASGEGVLVALRTMR
                     EDPEICDMFKREESKYNKAIENLVRTEYAKFAQDGIEKSYIETGVDEYNVLTAKDEKV
                     CSICGGKAKNNPYKLSEAIIGENRAPFHGRCRCTDVPNMPKLGKDIDEEYERLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            5044..5361
                     /locus_tag="LP245_002186"
     CDS             5044..5361
                     /locus_tag="LP245_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520081.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYENMGCIVVRTDYKEGK
                     SSN"
     gene            5488..6111
                     /locus_tag="LP245_002187"
     CDS             5488..6111
                     /locus_tag="LP245_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBL1520082.1"
                     /translation="MIMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            6126..7016
                     /locus_tag="LP245_002188"
     CDS             6126..7016
                     /locus_tag="LP245_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HBL1520083.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            7039..7254
                     /locus_tag="LP245_002189"
     CDS             7039..7254
                     /locus_tag="LP245_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520084.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            7266..7607
                     /locus_tag="LP245_002190"
     CDS             7266..7607
                     /locus_tag="LP245_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520085.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            7607..7978
                     /locus_tag="LP245_002191"
     CDS             7607..7978
                     /locus_tag="LP245_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520086.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            7971..8366
                     /locus_tag="LP245_002192"
     CDS             7971..8366
                     /locus_tag="LP245_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBL1520087.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            8368..8745
                     /locus_tag="LP245_002193"
     CDS             8368..8745
                     /locus_tag="LP245_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520088.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            8746..9354
                     /locus_tag="LP245_002194"
     CDS             8746..9354
                     /locus_tag="LP245_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1520089.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            9354..9695
                     /locus_tag="LP245_002195"
     CDS             9354..9695
                     /locus_tag="LP245_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520090.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            9937..12726
                     /locus_tag="LP245_002196"
     CDS             9937..12726
                     /locus_tag="LP245_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBL1520091.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEEFRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVESVK
                     DAWSGIKEWFSNTWQGIKNGATGLFDKTVETSMNAVDSVKNAWSNTKQWFSDIWQSIK
                     DSATEKWNEIKGSIMEVAGPLITGLKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LTPVLFITSMISGGWEETKNNMIGVWNNIKESALNIWESIKNIFVSYITNIYFAALNI
                     WTGFKLTLINIWNEVVSQAKSIWINVKYFFINLWIDIKYFAIQKWIELKFGIIQTWID
                     LKYNAITTWNNIKQFFKDTWQNIKDIAYNTWISIKNSMINTWNNIKESFWNIVTGIVN
                     SAENAWTNLKNGVSKAINRVKEIFDSLREINLFEIGKNIIDGLINGVVEKWNALKKTI
                     KGIAGSIKDSIKGALGIHSPSRWMRDMVGKNIVQGIIVGIDKEKSKLDQTMTDLVKTP
                     SVQPVITGSNSQPVVQAKQNTSSNAVNEIHLHLNVYGDLPDSMIKQIAKKMKTELTRQ
                     MKRDADAVGGTLYAT"
     gene            12716..13456
                     /locus_tag="LP245_002197"
     CDS             12716..13456
                     /locus_tag="LP245_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL1520092.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKAYYKNVTRKIECYYKAPSIDLVQEWEDRITEWLDMNSYSDFILYYDQQYIYQ
                     AIVTEAPEFKGTRKTGNIVPFEFTVSLRPFKENYSGRFAIQQIKAFELFNPEKYASKP
                     LIKLSGSGDASFYINNDKYDLKLLDRELYIDSKLEESYRKLDDNLEHQDHVTLFLDFP
                     FLYPGKNEIKWTNNIHSFEIIPRWWRKV"
     gene            13453..16164
                     /locus_tag="LP245_002198"
     CDS             13453..16164
                     /locus_tag="LP245_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBL1520093.1"
                     /translation="MIPRIYSPTETDFSTNGLGILKDTTKCEIYEVANGKYELELEYP
                     LGTRFDEYFENDYQIKAKSNDQEEYHIFFIDDKDIDTFLDTVTIYAQSRTNRLGRRAV
                     TFAGVDSKTGREAMAIIENNMDKKSDIRLYSDITTVSSTTFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRDNIGTIRYGKDLSGLKVKLDWTGVKTRIIPYADPQS
                     DAGTTSRIYGSPVDSEYINNYPDVYTEHVQFTEEQGVKDVNSLNKIAKNYFKTINPGC
                     DKPKISITVEFDKLTDTEEGKEFAKIRNYGLFDTFKIYHRKYKLYFESKVSGVQYDSL
                     SEKVLKLEAGDAQVAFYQQQAVTIQDKLKDYATNNYMSSFNDYVSSMIAGQGNAGGYV
                     VLWPKEKPSNIFIMDSPDLNKAKEVLRMNKNGIAFSKNGWNGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSNSSIGTI
                     GTTDSAGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVNGKEITGNNSGGSDPGTIPPQLTTEAEKRAWKIWTMLKARGYSEYAAAG
                     ILGNIQGEVGASMNPDTEQLGGPAYGIVQWDGSAYPLVGSPTWNGREYVQRLMNTAGI
                     QEDYRSIEAQVKLLDWCMFNGQWLGKVNPTTVSGFKSINDAKSAAYAFEMNFERPASA
                     HPERQNYAQSWYNKLHGLTSPEPGGNFICPIQKPVTVTSECGWRTSPINGGQEFHNGI
                     DLVNGNPNTPVFAALDGEVVQAGANYYDWYGNYVVIKHNNGKWTGYAHLSRIDVSVGQ
                     KVQKGAQIGLMGTTGPSTGEHLHFQIMKNYWPQPVVDFENPRNYIQF"
     gene            16177..>16988
                     /locus_tag="LP245_002199"
     CDS             16177..>16988
                     /locus_tag="LP245_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBL1520094.1"
                     /translation="MSKWNVVLSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGT"
BASE COUNT         6056 a         2424 c         3544 g         4964 t
ORIGIN      
        1 gataggtctg agacaaaata ataataaaag gaacatcgtt ttattattgt ttcacaatta
       61 agcttcgata gacagcaacg gaaatattaa gaataaggat gtgaatttta actccttcta
      121 aattgttctt attatctatc atccgttgct gtctattgtt acatacagat cgcttaggcg
      181 gtctttttat tttggccgaa aacctacatt ttcgatggcc gattattgga ggaggaatag
      241 catgttcaaa ctatctgaaa tcattaagaa gtccgacgtt gagaaattag agatgttaaa
      301 aaagaagttg aagaaatagc agtctcttcg tgaggctgtt ttattttgct cacaaaaata
      361 gaccactatc gggtaatagt ggtcaggaat taaatgaaaa agatgttagg gttgttagct
      421 aagtataaca tcataacgct tacaaaacaa tgcaagaagg ataaattatt atgagaactt
      481 actggtatgt gtcattaaac aataaatatc cgaagccaat gaaaggacag cataggcgtg
      541 tagtcatgtc tgttcaaatg aaggcgaagt attcgattgt agaaatgatc agagaggcaa
      601 cgccagtaga gattgattat tgcaagctag tctattgtgg gtgcggccgt tggaaagagg
      661 atcatgtaca aaaaaatatc agcaagtaca tatagagagg cggtgattaa ggatggaaaa
      721 aagcgatacg aaagcgaaca gatacaaacc tactgctgca gagaaaaaac tcttggaagt
      781 attgataaat ccagataact taggcaaacc ggtgcaagag ttgtgttcac tggcgaaaat
      841 aggtaggacc aaatattacg acgccatgag caaagatggc tttgttgatc tagttaacga
      901 aacaacaatg gatctgatca aaggaaaagc ttctgatgtc cttaatgcca cttacaagta
      961 tgcattgact gaaaaaggtc atcaggatag gaaaatgatt ctgactattg ctggaatcta
     1021 tgcagacaaa caagaactca aacattctgg cggcgtcgat atccgaaaac agtatgagaa
     1081 aatgtccgat gaagaattag aagagttggt gaaacggtat gaaaaaatca acgactctta
     1141 atcgtgttga gtatgccgtt gttcaaagag agctagccat tcgaaaagct aggaaaagtt
     1201 tttggctatt ctgccagctt ctttatccag agttttacaa agatgatcgg ttgtatttga
     1261 aagatttatg tcatacgcta caagattttt acgaagataa aatcgacaaa aaaattttgg
     1321 ttattaacat gccgcctcga catgggaaga cttttacagc gcggctattc gttttatgga
     1381 tgtttggaca aaatccaaag acgaaaatta ttaccggatc ttataaccaa atcctgtcat
     1441 ctttatttgc gcaacaaaca cgtgatggaa tcatggttga aaacgaaaat gttaaggctg
     1501 aatactttaa agatattttt ccagaggtgc aaatcaaata tggagatgct gcaaagggtt
     1561 tctggtcttt agatggttca gaagaaaaga attatttagc gacttctcct ggtggaacat
     1621 ccactggtat tggcgcgaat tatgtaattg ttgatgacat cattaaaacc gcagaagaag
     1681 cctataacga gcgtgtttta gattctcact gggaatggta taacaacacg ttggcccaac
     1741 gaatggaacg gccacgtaaa cagatattga ttatgacacg ttggtcaagt aatgatttag
     1801 ccggaaaaat gttgacgaga cgaaaaaata atgttcatca gatctgttat aaagcagtac
     1861 aagaagacgg ctcgatgttg tgcaacgaga ttatgaccca cgatgagtac ttagatgtgg
     1921 tacaagaaat gaatgtagat attgcagaag ccaactatca gcaagaacca attgaccaaa
     1981 aaggcaggct atatcagaag tttcttactt atgatacgtt gcctgataac attatcaaaa
     2041 tatggaacta caccgacacc gccgacaagg gtgccgatta ctttgcgtct cctgtttttg
     2101 ctgagacgtc tgatcatgat gcttatatta tcgatgtcat gtatacaaaa gagccgatgg
     2161 aaacaactga aatagcccac gctaatatga ttattcgcaa tcgagttaat aaggtacgga
     2221 ttgaaggaaa caatggcggg cgtggattca gaagaaattc agaaagaatt acaaaagagc
     2281 gaggctatcg aggtgcagta tttgaagact ttcatcaatc ggataataaa ctgtctagaa
     2341 tactggcgaa tagtgcttgg gtggaaaatc atgtttacta tccagatgat tgggcgacac
     2401 gttggccgga cttttatgag gctatggtta gttatcaacg tgaaggtaag aacgctcatg
     2461 atgatgctcc ggatgcagtt acaggaattg cagaaacgat tatagaagca gatgacttcg
     2521 agtttattgc ttattaggag gtgggtcttt gttttattct ggaatcacat tgaaaaaata
     2581 caaacgttta agaacgaaat attcaacgca aatcgaagaa ggattattcg atcctaacgc
     2641 ttttatggaa gatatgaaac cctttttcga tgatcgagaa agaaagtatc ttgcttatac
     2701 tagcgagaaa aacgagatcg acagtcgtga gaaaccaaaa acaaaaatca ttaaggtcaa
     2761 taacaagatt catgcgggaa tgtattcagt ggtcgttgat caagcagtta accatttcac
     2821 aggaatacca attaaatggg attatgatgt ttcggaacag aaaaggacat tcattcaacg
     2881 aatgagagac aaattactgg gtaatgatat cagcgcccct tctaccccag aagaatttga
     2941 aacactcacg agacaattaa gtactatgcg gtttggaatg ttagaccccg atactgcaac
     3001 atttcaagga gcgacagggc ttgctttcag attactggag cctgttgaga caaatgatgg
     3061 ttgggaacta agagcaagca acattgagcc gtggaaagct gaaaagtacg aaaacggcgc
     3121 agtgtacatt aaagagaaat acgatccata tcaaaagaag ttttatgaag agatgaaggt
     3181 tgtcacgccg aaatcaatat ttacttatgc tcgatatact gattaccctg gcacggtaca
     3241 aggagcattt aaaacgctgg gtaatgttcc taatccttta ggcgttatca atcttacgga
     3301 gtttaaaaac aatacaaacc gttactgtga ctttgaagtt gcagaggaga ttagtgatgc
     3361 tattgatcgt gttttatctg atcagcagaa cgagattgaa caattcaagt tagcttatat
     3421 gctgatcact ggggcagatt tgtccgagga taaagccaag aagatgatgg agcaactagg
     3481 gatcatcaat ctgaaagacc ctaatgcgaa agccggctac gtgacaaagg atctacaaaa
     3541 ggatttcaac gagtatcatt ttgatcttct taaaaagcaa ttctacacgg tgtgtaaagc
     3601 aattgatttc aatgacgaag tctttaagtc gaatagttct ggggaagccc gaaagtggca
     3661 aatcattagt ttagaagcta agacaaatac caaagaacag tactttcgag aaggattgaa
     3721 agagtgtgcc gaggttatgg ctgcttattt ggattttgcc gagaaagtta caattgatcc
     3781 ggaaaagatc attttcacct tctctcgttc gcttccaaca gatttaagct acctagctga
     3841 ggcattgcct aagttggcac catacgtttc taagaggacg attcaaagtc agatcccgtt
     3901 cgtcacagat gttgattatg aaaacgaaat gattgacgtc gaaagcagac aatcttaccc
     3961 agacggcgag tatggaggtg gcatcgttga gtcaaataga aacgaagtac tggaccaaac
     4021 gtcgagaact ggaagattta gcaagactca aaatggaaaa tcaaacgcta aagaaactaa
     4081 gtagtgtctt tcctgatgcg ttgaaagaaa ttcaagcgga gttattatcc caagctgatt
     4141 tacacgatat tacctatgct gagatgatgg aattttatag tacaagtgat cagaaaaaat
     4201 atcgtgaata cgttgaaaag aactacaaat cactgaagat gtatgatgca aaatacaaag
     4261 agttcatcga agaatacttt ccttctttcg actacgccaa agtgaatcgg ctgcttcaaa
     4321 tgaggtcaga tatttttcga attcttgcag agagtgcaat agatgcagat gtgaataaat
     4381 atttttcgga tcggttagaa gatatcttgc aacgttcgta tgtatcaaac gcaaacgtat
     4441 ttgcccagat tttgaacgta gatttgccga attacttatc aaaggaagaa cttgaacgtt
     4501 acctgaacta tccttggtca ggtaagacat tctcgcgtcg tttatggggc aatatttcat
     4561 ctctagaaca aaagctatct aacgccatta caactagtgt agcaagtggc gaaggagttc
     4621 tcgtggcatt acgaacaatg cgagaagacc cagaaatatg cgatatgttc aaaagggagg
     4681 aatcgaagta caacaaggcg atcgaaaatc ttgtgagaac agaatacgct aaattcgctc
     4741 aagatggtat tgagaaatct tatattgaaa ctggcgtaga cgaatacaat gtcttaactg
     4801 caaaagatga aaaggtatgt tcaatatgcg gtggcaaagc aaagaacaac ccatacaagt
     4861 tgagtgaagc gatcattggt gagaaccgtg cgccttttca tggccgatgc agatgtacag
     4921 atgttcctaa tatgccgaaa ttaggaaaag atattgacga agagtatgag cgtttatttg
     4981 gcgatttatt agatgagttt gcacatgatt cttttggaat taatttgaaa cggaggaagt
     5041 agaatgaaag atttttttga agcagtacta acaattaatg taaatgctga tattgcagaa
     5101 gcctacaaaa cagctattga gtctgagaac catcctaatg gcttgagaga ccattggaat
     5161 ggcaattatg cctacgtggt tattggcgat caaactgtta attatcaaga taatactcca
     5221 gttgataaga ataccgttaa tttaacgatt caattattat ctcattcatt accaaattta
     5281 aaagaaacag ttgattggta tgaaaatatg ggatgtattg ttgttagaac tgactacaaa
     5341 gaaggaaagt ctagtaatta ggctttttta ttttgtccga aatgacgtta aactagcgca
     5401 atactgggct tggttgaatg gtggggcgca actattaaaa ctcaaagcaa tgcggggcgt
     5461 gaaaacgaat cgtggggcga aaggagaatg attatgaaac acaaatcatt aatgccaatg
     5521 aatttgcaat actttgccga aggtgacgat caaaagtttt cttttgatga cttcaaatct
     5581 tttgtggaat ccaatgaaga agctcaaaaa tttattcagt cacaatctca aagtgttgcc
     5641 gacaaacaat tggaagcttg gaaacaaaat aacttagata aaattaaaca ggataccatc
     5701 aaggaatatg aggaatctaa gaaaaacaag tcacctgagc aaattcaact ggaaaaacta
     5761 caagctgaat ttgaagcaga aaaagcgttg cgtgtgacaa gtgataataa agcatttgtt
     5821 gcagaacaaa ttgctggatt agaactagat ggagagttaa aagagtctat ttctcaattt
     5881 atgctaaata atcttgttag ttcggataca gatttcacta agaatgctgt tgaaggtttt
     5941 acaagtgttt tgaatgcaat taatgagaaa catgcagatg cattaaaaga actacaaatg
     6001 aagtctgcat ttggtggaac tcaacaatcg aataaccagg ttcagcagaa caatgaaaca
     6061 ttaacaaatc cagaagaaca attaggacaa attcttcaac aatttaacta ggagagtgaa
     6121 aaattatgaa aaaaacatct ttaaataatt tagagtattt ggatatttca ccagcgatta
     6181 atgctatgca agtaccaaat acaccttttt taagctattt acttggtgct ggaaaaacag
     6241 agccagcaaa ctcgacagaa attaaatggc gtgaatatga tatcaacaac gatgattctt
     6301 ctgaaaaact tgagggcgga gaatatccag atgctgaatc aggtcgaact tggtttaaca
     6361 actatactga aatttttaga aaatcaacct ctgtatctgg tacattagat gctattaatg
     6421 tgaatggagt cggaaatgaa ttaactaatc aagtagcact acgtggtatg gaaatgaaaa
     6481 ttgatttgaa ccgaaaattg attactggtg taaaagctga tgaaaatggt tctaaaggtc
     6541 gtcgaatgaa tgggattttg aacttgatca attcagcaaa taaggcagaa acagccactg
     6601 cgggtgcagt aacaagaaaa gatatcgata ctttatttaa attgatgtat gaaaaaggtt
     6661 atatgggaga aaaactatgc ttgatttctc cagatatgca ggagttaatg actgatgagt
     6721 tagatggaaa atcaacaaaa attgttcagt tcggggaaag agtaactttt ggattgcaaa
     6781 ttggaaatat cgtgtctaat tacggtacag gtattgctct actagaacca tcattgccaa
     6841 aaggaacaat tgccgcaatc gatactaatt atgtgaaact acgtccatta cgtgaatgga
     6901 gagcagaaga acttgcaaaa acaacggatt ctagacgtat cggtcttgta ggtgaatact
     6961 ctcttgaata caatgcttca aactctgggg caattttaaa tttaaagtct gaataaaagg
     7021 gagttagtac tccctttttt gataggagga attacagtgg taaaaaaaga tgaaactaaa
     7081 aaagatgaag tcgtgaaata tagagtaggt aaaactaaaa attttgttgg gtttgttcat
     7141 cctaaaactc gtagatttat cacagcagat tcaaataacg aatttatcat ttctatagat
     7201 gataaagaag caattgcaat tttggaagat gcaattgatg ttaatgaaat ttaggaagtg
     7261 atctgatgga tgaatcgcta aaaacggaaa tcattgagtc tacaaaagaa gattttccag
     7321 atttgagtga agaacgcata actaatttat tagaaataat tttgctagaa attgaatcat
     7381 acaacacttg taaaaatgat atttcatggg aaaagttaaa aagcgtgatt agtgaagtgt
     7441 tgtataaaat aataaaaaat gaatcagaaa aaacagtatc ttcagttaga cgtggcgata
     7501 caacgattag ttatgcttca acaacaaatg atgttagtga gttacttcta ggctatggtg
     7561 atttgatacg aagagttatt ggttgtggag gattggagtt tttttaatga atgaagcaga
     7621 tattttagaa actacttatg aagatagttg tattattgaa agactgacgg acattgaaga
     7681 ttctaataca aatattacta ttcaagatta caaaaaagta tatgataatc ctatttcttg
     7741 cgctctttca caaggtcaaa tcgatggact agcagtcata gaagatggag agatggtaaa
     7801 tgtttcaact gacacatata aattatttgt tcatcctaag attaaactaa aaaaaggaga
     7861 tcgaataaca ataactcaaa aggccagtgg cttaattttt tctctatttg ctactaagcc
     7921 tttttactat cctagtcatt gtgaagtgaa tttgatagga agtgagaaaa atgggtaatc
     7981 tcaaatatga atcaaatgca gaaaagatca ttgagaattt taaaaatatg actgtaattg
     8041 ctcaaaaaga aggaatatcc ttcgttaacg attcaatgaa taaagtcgtt agtttagcta
     8101 aaccattaac tcctgtaaaa tcaggtaatt taaggcgagg atatcgtgta gtaaaagcta
     8161 gaaaactatc aagcggtcga attgttggag cagttataaa caatgaacat tattttaaat
     8221 atgtagaaga aggtcatagg actaaaaatg gtggctttgt caaagggaaa ttcatgttaa
     8281 ctcgtgcaac gaatcttgca aatatgtctt atattcctcg aagatttaaa caaatggcaa
     8341 taaaaatcgt taagaaagga aagtaacatg aaagatgaaa tcattgctgc aatcagtagc
     8401 aaattaaaag aaatctatcc tgatgggaca atatatcttg attcagttat gcagtcaact
     8461 aaagattttt atttcgtttt atcagtaatg gaatctggaa ctgaaaatgt aggaattgat
     8521 attcaaaatg tttctttctt aattgatatt gcattgattg ataataaacc taatagaaat
     8581 ttaattaatg aattagtctc acgttgtggg acttttttta atacgattac aatcgatgag
     8641 caaatattat ttccaaaagc ctatttacct gatgaagcag atggtgttca acatattcgt
     8701 tttacattag aatttccaca atatattgaa tggagtgaaa gataaatggg agaaaaaaga
     8761 agtaaaaccg gaattatttc tgtcgaaaaa cctacttggt ttcctttgga agatgagaca
     8821 gggaatttcc cggtatatgg tactgcgttg ccaatgggaa cagcagtaag tatcaaacca
     8881 acagctaatt atgaaacaac acaagattat ggggattcag tggttcaaga tcaatttaca
     8941 gcttttggtg gtgcagaagt tgaactggaa gcaaatggat atactcataa agttttatct
     9001 acaattactg gagggaaaat tgttaaaggt ggtgccttgc gttctggaga agatattgcg
     9061 caagatggtg cgtttgcata tagacgtaaa aaatcgaatg ggaaataccg ttatacggtc
     9121 ttttataaag gacagtttgc tctagattca gatgaaacgt caacgattga aggaagtaaa
     9181 gtaagtttta ctcatccaac ttggaagggt tcatttgtag atgtaccagg acttggatat
     9241 atgtattcag ttgatgaaga tgatgaaggc gtggataaag caatgatcgg aaattggttt
     9301 acaaaagtag caattccaat tgaagaagca gaactttcag gaggtacaga ataatgtcaa
     9361 aatatcaaac aacgattaaa ttaacgaaaa aagatgaaga aggtaaatat gagcaagtac
     9421 aatttaaatc tgctgaattt ttaccaggaa cagttgtaga agatgctgca ggagttatgg
     9481 aagaaatgca aacagcgact gataaacaat cagttaaaaa agctttaagt cgtgcttatt
     9541 catttattgc agatacttta tttgagggac aatttactgg tgaagattat tgcaaaggaa
     9601 ttgatgctcg tgagattgcc tcattgacag gaaaattatt gaagtctgtt actgcaggtt
     9661 ttgatgaaac ttatacagag acgaaaaaaa agtaagtgag gcgctcaagt caccttcatt
     9721 taagtattcg attacttacc gagaattaga tataaagacg caattactcg aagcaggttg
     9781 gacgttacca gaaattgaac gtactgactt ggatgagtta atgcgtcttt ttgcttttag
     9841 agatgcggta aaagagcatg aagatgttga gtactatgat aatttcactc aattttagga
     9901 ggtgatactt tgaataacga tgacctaatt ctgaagatga tactagatga atctggtttt
     9961 actgccggta tgaataatgc tgtcaaaaag ttgaactctt ttgatgaaac aatcgaaaga
    10021 aaaagtagaa atagtggcag ttcattaggt agtatttgga aaatatttgc tggaagtttt
    10081 ctagctagcg gagtaactag aatcgtagga gctggctttg atctaatcaa gggttccata
    10141 agtggagcgg ttgatcgagt agatacgatg aataacgctc tacgaaattt ccaaaatatg
    10201 ggatttagta attcagaaat tatgaagaat atcggaaaga atgggctttt atctcaaggt
    10261 attcaaggac ttcctactgc tttgaatgat gcgataagtc atgttcaact tcttgcttct
    10321 tctacaggtg atttaactcg ttcaactcaa atatttaaag ctttaaatga tggaattctt
    10381 ggtttcggtg gttcaactga tcaagttaat gaagctgtta ttcaattatc tcaaagtttc
    10441 tcaaacggaa aagtagacgc acaaacttgg aactcaatga tcaacgctca acttggacct
    10501 actctttctg ctattgctaa aaagatggga attacaatgg gagatctgaa agaaggttta
    10561 tctcaaggta agatttctgt tgaagaattc caaaatcaat taatagaaat ggataccaaa
    10621 ggtggcggag gacttaaatc attaagtcaa atcgctaaag attctactaa gggaattaaa
    10681 acctctatac aaaatgcaaa aacagctgtt acacgtggtg ttggtgaggt aatagaagga
    10741 ttaaataaag cattagtaga ttcagattta ggtggattta agggaattat tgataaagtg
    10801 ggcagttcaa tggaatcgtt cttaaaagta attgctgcaa atattcctac agcagtatca
    10861 tttttaagta atttatttaa cgaaattcaa aaatttggtt ctgctttgaa attcatgatg
    10921 ccctttcttg ttcctgcagc taccgctttt ggagcgttca tgtttcaact taaaggtata
    10981 ccagcaataa taaaaagctt caataatttt aagaatgcca taattggcgt tggaaattca
    11041 ttaaagatta tgggggcaat agctgctgct aattcatttg ttttaattat tggtgcagtc
    11101 gttggtgcaa tagctgtttt cggttacttt atggcaacca atgaagagtt tagaaacaag
    11161 gttatatcta tttggaatga tgtgaaagat tccgtaattg gtgtattaaa aaatataaag
    11221 gactggggaa ttgatacttg gaattctgct aaagaaatgg catcaaatgc tgttgagagt
    11281 gtcaaggatg cttggtctgg aataaaggaa tggttttcaa atacttggca aggcattaaa
    11341 aatggagcaa caggtttatt tgataaaaca gtagaaacat ctatgaatgc ggttgatagt
    11401 gtaaaaaacg catggtcaaa tacaaagcaa tggttttctg atatttggca gagcataaaa
    11461 gattcagcaa ctgaaaaatg gaatgaaatt aaaggttcta tcatggaagt tgctggtcca
    11521 ttgattacag gtttaaagaa cgcattcttg catgtcactt tttatttaga gaccttatgg
    11581 aataatctag ttgagattgg taaaaatgtt tttgagattt taaaaaatgt tatacttacg
    11641 ccagttttgt ttattacctc catgatttct ggtggatggg aagaaacaaa aaacaacatg
    11701 attggtgtat ggaataatat taaagaaagt gctctaaata tttgggagtc tataaaaaat
    11761 atttttgtta gttacattac aaatatttat tttgctgcgc ttaatatttg gacagggttc
    11821 aaacttactt tgataaacat ttggaatgaa gtagtaagtc aagctaaatc aatttggatt
    11881 aatgtaaaat acttttttat taatctttgg attgacatta agtattttgc tattcaaaaa
    11941 tggattgaat taaaattcgg gattattcaa acttggattg atttaaaata taatgctatt
    12001 actacttgga acaatattaa acagttcttc aaagatactt ggcagaacat taaagatata
    12061 gcatacaata catggatttc tataaagaat tccatgatca atacttggaa taacatcaag
    12121 gaatctttct ggaatattgt tactggaatt gttaactccg ctgaaaatgc atggactaat
    12181 ctaaaaaatg gtgtttcaaa agcaattaat cgggtgaaag aaatctttga ttcattaagg
    12241 gaaatcaatt tattcgaaat cggtaagaat atcattgatg gacttatcaa tggtgtagta
    12301 gaaaaatgga atgcattgaa aaagactatt aaaggaatag ctggaagtat caaagattct
    12361 attaagggtg cattaggtat tcattctcca tctagatgga tgagggatat ggtaggtaaa
    12421 aatattgttc aaggtattat cgttggtatt gataaagaaa aaagtaaatt ggatcagaca
    12481 atgactgatt tagtgaaaac tccgtcggtt caaccagtta ttacagggtc taatagtcaa
    12541 ccagtggtac aagctaaaca aaatacatct tcaaatgcag tgaatgaaat tcacttgcat
    12601 ttaaatgttt atggagatct acctgattcg atgattaaac aaatcgccaa gaagatgaaa
    12661 acagaattga cgagacaaat gaaacgagat gctgatgcag taggagggac attatatgca
    12721 acttaaaaga ggacaatttt ttatcaatca acattattct tctgagttta acgtatatat
    12781 tcaaaatagg cctgcctctg tttcagctag tcgtgtaatt gaattgagag aacgtgaagg
    12841 caatgactca attattatcg ataaagccta ttacaaaaac gttactagaa aaattgaatg
    12901 ttattacaaa gcaccatcga ttgatttagt gcaggaatgg gaagatcgaa ttactgaatg
    12961 gttagatatg aactcttaca gtgattttat tctttattac gatcaacaat atatctatca
    13021 agctatagta accgaagcgc cagaatttaa aggaacaaga aaaacaggga acatagttcc
    13081 atttgaattt acagttagtc ttcgaccatt caaagaaaat tatagtggtc gttttgctat
    13141 tcaacagata aaagctttcg agttatttaa tccagagaag tatgcttcaa aaccgcttat
    13201 taaattgagt ggttctggag atgcttcttt ttatattaat aatgataaat atgatttgaa
    13261 actattagat agagaattat atatagattc taaactagaa gagtcttatc gaaagctaga
    13321 tgacaattta gaacatcaag atcatgtcac tttattttta gattttccat ttctataccc
    13381 tggaaaaaat gaaatcaaat ggacgaataa catacattcg tttgagataa taccaaggtg
    13441 gtggagaaaa gtatgatacc aagaatatat agtcctaccg agacagattt ttctacgaat
    13501 ggtttaggga ttttgaagga caccacaaaa tgtgagatat atgaagtagc aaatggaaaa
    13561 tatgaattag agttggagta tccattaggt actcgatttg atgaatattt tgaaaatgac
    13621 tatcaaataa aagcaaagtc aaatgatcaa gaagagtatc atatcttttt tattgatgat
    13681 aaagatattg ataccttttt agataccgta actatttatg cccagagtcg tacaaatcgg
    13741 cttggaagac gagcggtcac ttttgctgga gtcgactcta aaactggtcg agaagcaatg
    13801 gcaattattg aaaacaatat ggataaaaaa tcagatatac gcttatattc tgatattaca
    13861 actgtatcaa gtacaacttt tgaagcaaga aatgttttaa attgtattgc tggtgaacaa
    13921 ggatctttac ttcagtattg gggcggagaa attaaacgtg agccttttaa gctatcttta
    13981 ttaaagcgaa gaggtcgtga taatattggc acaatccgat atggaaaaga tttatctggg
    14041 ttaaaagtta agttagattg gacaggcgtg aaaacaagaa ttattccgta tgctgatcct
    14101 caaagtgatg caggtacaac tagccgaatt tatggctcgc cagtagatag cgaatatatt
    14161 aataattatc ctgatgtata tacagaacac gttcaattca cagaagaaca gggagttaaa
    14221 gacgttaata gcttaaataa aatagctaag aattatttca aaacaattaa tccaggctgt
    14281 gataaaccga agatttctat taccgttgag ttcgataaat taacggacac cgaagaagga
    14341 aaagaattcg ctaagataag aaattatggg ttatttgata cgtttaaaat atatcatcga
    14401 aaatataaac tatattttga atcgaaagtt agcggtgttc aatatgattc attatctgaa
    14461 aaggttttga aattggaagc tggggatgct caagttgctt tttatcaaca acaagctgtt
    14521 actattcaag ataaattaaa agattatgct acgaataatt atatgagtag ttttaatgat
    14581 tatgtgtcct ctatgattgc aggtcaagga aatgcaggcg gttatgtagt tttatggcca
    14641 aaagaaaaac cttcaaatat ttttataatg gatagccctg atttaaacaa ggcaaaagaa
    14701 gtattaagaa tgaacaaaaa tggaattgcc ttttctaaaa atggttggaa tggtcctttt
    14761 aattccgctt ggacattgga tagtatattc aatgctaatt ttattcaaac aggattaata
    14821 aaggcagata tctttcaaaa ctcttttaat aaaactggag atgtattgaa attagttaat
    14881 ggactacttc aaatttggaa taacaaaaag aaaataatgg agttaaccaa aaaaggaatg
    14941 gagttttgga attctaatag ttcaattgga acgattggaa caactgattc tgctggtaat
    15001 ccttttcctg gagcttctac tcccacacct attgaagata attctttagt tattcgtaca
    15061 aatggagacg gcaaatatat tttgatttct cctaaagttg gtaaaggatt agttttatta
    15121 ggaaatggta aagcaattta ttttggagac ttagatgtac aaggcaaact cacagttaac
    15181 ggaaaagaaa tcacagggaa caacagtgga ggaagtgatc ctggaactat ccctcctcaa
    15241 ttgacgacgg aagctgaaaa aagagcatgg aaaatttgga caatgctgaa agctcgtggc
    15301 tattctgaat atgcagctgc aggtattcta ggaaatattc agggggaggt tggagcaagt
    15361 atgaaccctg atacagaaca acttggtggt ccagcttatg ggattgttca atgggatggt
    15421 tctgcttatc cgttagtcgg atcaccaact tggaacggac gagagtatgt tcagcgtttg
    15481 atgaacaccg cagggattca agaagattat cgaagtattg aagcccaagt aaaattatta
    15541 gattggtgta tgttcaacgg tcaatggctc ggaaaagtaa atccaaccac agtatcagga
    15601 tttaaatcga tcaatgatgc caaaagtgca gcgtatgctt ttgaaatgaa cttcgaacgc
    15661 ccagcttctg cacatccaga acgccaaaat tatgcccaat cttggtataa caaattacat
    15721 ggattaacta gtccagaacc tggagggaat ttcatttgtc caattcaaaa accagtgaca
    15781 gttacttcag aatgtggatg gagaactagt ccaataaatg gcggccaaga atttcataat
    15841 ggaattgatc ttgtaaatgg aaatcctaat acacctgttt ttgcagcatt agatggggaa
    15901 gttgttcagg ctggtgctaa ttattatgac tggtatggta attacgtggt tattaaacat
    15961 aataatggga agtggacagg ttatgctcat ttgtctcgta ttgatgtttc tgttggacaa
    16021 aaagtccaga aaggtgctca aataggcttg atgggaacaa ctggtccatc tacaggagaa
    16081 catctacatt ttcaaattat gaaaaattat tggccacagc cagttgttga ttttgagaat
    16141 ccaagaaatt atatccaatt ttaaggtggt gattctatga gtaaatggaa tgtcgtttta
    16201 agtacaacag aaccatataa ttatgtgggg atgattcaag ttcgacaagg caataagaat
    16261 acagaggtta tggaagcgac tatagttgaa aatggtcttc cctacgattt atcagaatgt
    16321 aaggtatatt ttgaatcagt tgtaggtggg aaatatccag tccaattaga aacaaaaatt
    16381 gtggatgcta aaaaagggaa aattaactat atttttgata aatattccat gcagtgtttg
    16441 catcgacaaa cagccaattt cattatattt aaaggagaag acttgattgg aacaactcaa
    16501 gacttctcct attttgtcat caatgctgtt tcaaaaacag aaggagaaat gggttcttat
    16561 tggcaatcaa ttgaagattt aattgctgat atgacagatt ttattaatga aaataaaggc
    16621 gattttacgg actggatgaa tgaaaggaaa gaagaatttg atcgctggag agaagaacag
    16681 gagaatagtt tccaagattg gagagaagga caagaatcag attatttgtc atggtttgaa
    16741 tcaatcaagg atattttgaa gtctatcgat ccaggtggag taatgttagc cgaattaatg
    16801 gatgcacgtg ttgatattca aggagttcgt catgcgtcta tttcagagcg cttgctggca
    16861 gatatggatt atctatatca gaaattacga gcaacacttt tcacgattga atacggtgag
    16921 attgaagtga ctgatatttt gcaggatgat ctcttttcag ataatcacga agtcgaaaaa
    16981 gttggaac
//
LOCUS       DAFEEZ010000062        16827 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.065, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000062
VERSION     DAFEEZ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.065"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(43..409)
                     /gene="ssrA"
                     /locus_tag="LP245_002200"
     tmRNA           complement(43..409)
                     /gene="ssrA"
                     /locus_tag="LP245_002200"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(580..1353)
                     /locus_tag="LP245_002201"
     CDS             complement(580..1353)
                     /locus_tag="LP245_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1520095.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1497..1847
                     /locus_tag="LP245_002202"
     CDS             1497..1847
                     /locus_tag="LP245_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBL1520096.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            1828..2544
                     /locus_tag="LP245_002203"
     CDS             1828..2544
                     /locus_tag="LP245_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1520097.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2544..3992
                     /locus_tag="LP245_002204"
     CDS             2544..3992
                     /locus_tag="LP245_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1520098.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4062..4571)
                     /locus_tag="LP245_002205"
     CDS             complement(4062..4571)
                     /locus_tag="LP245_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520099.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4561..5286)
                     /locus_tag="LP245_002206"
     CDS             complement(4561..5286)
                     /locus_tag="LP245_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520100.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(5544..6884)
                     /locus_tag="LP245_002207"
     CDS             complement(5544..6884)
                     /locus_tag="LP245_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL1520101.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            complement(7051..9171)
                     /locus_tag="LP245_002208"
     CDS             complement(7051..9171)
                     /locus_tag="LP245_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL1520102.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            9401..10579
                     /locus_tag="LP245_002209"
     CDS             9401..10579
                     /locus_tag="LP245_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBL1520103.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            10595..11353
                     /gene="aroD"
                     /locus_tag="LP245_002210"
     CDS             10595..11353
                     /gene="aroD"
                     /locus_tag="LP245_002210"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBL1520104.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFFSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            11376..11861
                     /gene="ybaK"
                     /locus_tag="LP245_002211"
     CDS             11376..11861
                     /gene="ybaK"
                     /locus_tag="LP245_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBL1520105.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(11932..13185)
                     /locus_tag="LP245_002212"
     CDS             complement(11932..13185)
                     /locus_tag="LP245_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1520106.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            13302..14651
                     /gene="gdhA"
                     /locus_tag="LP245_002213"
     CDS             13302..14651
                     /gene="gdhA"
                     /locus_tag="LP245_002213"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBL1520107.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            14763..16109
                     /locus_tag="LP245_002214"
     CDS             14763..16109
                     /locus_tag="LP245_002214"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBL1520108.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(16417..16803)
                     /locus_tag="LP245_002215"
     CDS             complement(16417..16803)
                     /locus_tag="LP245_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL1520109.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         5411 a         3035 c         3442 g         4939 t
ORIGIN      
        1 aaataaggat ttaagcatct agcgaaatct gctgaaatct cacaatggag acggcgggag
       61 tcgaacccgc gtccaaacac atcgccactt aaaaatctac gttcatagtc aactcattta
      121 aggattcact ttacagcttg ccgagtgaca ggcattctgt atcgctagtc tgatgttctc
      181 tttttcaact tacagacgga aagttgaaac gtatcccact aaagttagga cccttactcg
      241 agcacatggg cgatgccgag aggatctacg ctaactgttt ttaggcagct aaagcgtaag
      301 agttgttttc gtttttagca gttatattta actgtaacgt ttttacgtag acgtaaccta
      361 cgaaacgcaa ttcaagctcg actgtgcctg tcgaatccgt aacgtccccg ttagctaaca
      421 agggttacgt gtatttttca tacaaaatta gtatagcata tattgggata aattcaataa
      481 aaaagcgaat catatcccat tatttatata ataactgccc ctttcttaag aaaaaataag
      541 cgattttctt aagaaaagag gtagcttcaa aaaaagatct taaatcagat caaaatactt
      601 caatgcgtgg acaattccgc cttctgtatt tttctttgtg ataaaggtag aaagttcttt
      661 taatccgtca taggcgttgc ccatagcgat tttgttgtcg caagcttcca acaaggcaaa
      721 atcattcgga ccatcgccaa atccaaaagt aggaactttt tccagctgaa gttctttttg
      781 cagacgtttg acacctgccc cttttgagat tcctttcttc actgtatcga tcgagtaagg
      841 accattccga taaaaagtta gctcaggaaa atgttcgtga tagtattcgt cacctgattg
      901 agataagatc agcaacatat ttactgtgtt ttctttaaag cctaaaggat caatttccgg
      961 aacatctgaa tgaatgaagt cgtaagcatt gatcattgtt tggctatgac cggtacacca
     1021 gattttctga tcgttatagt aagaaagttc atgaccgttc aactgtacat gatcatacat
     1081 tttttgacat tcttctgaag aaaatgtttg agaatagatt tcttcgccgt ctactcgaat
     1141 gaaagaacca ttcatggtga ccgcagaagt aatgcccgca tcttccatga tagagtggat
     1201 ttctgcttct gtacgtcctg tagcgatgac ggggagaaca ttgttttctt ttaatgcgtt
     1261 catagctttt gccacttcgg gtgtgatttt tgatttcgca tctagtaatg ttccatcaag
     1321 atcaaagaaa gtgattgcac gataatttga cacaaataaa actccttttt tattggaata
     1381 agtttatctt aacaaagaat gaacaaaaga caaacctttc gtgaagaatt cctgaacata
     1441 ttggttcagt caacaattta gagtatacta taagaagaga atttaggagg gaaagaatga
     1501 tttttttcag tattggtatc ttattcttaa taattggcag tctttttcgg attctgccct
     1561 caaaaggaaa tctgcctttt tatgggtatc attcgcctct tgccgcaaaa acagacgctc
     1621 attggcggct ggctcaaaag acaagcggaa actggttttt tcttatgggc ttactgatgg
     1681 cattgatcgg ctattattta aagacatctg ggcatacgaa ttattttctg attgaaatgc
     1741 ttctgctagt atttccaatt atgcctattt ttattatgac agaaaagaaa ttacagaaat
     1801 atgacctgga aactggaggg aacgataatg aatattttaa tgattgaaga taatcaatct
     1861 gtttctgaaa tgatgcagat gtttttctta aatgaaggtt gggaagcaac tttcaagtat
     1921 gatggaaaag aagggctcga tgccttttta gaaaacccac aacattggga tatgattaca
     1981 ctagacctga atttgcccac actggacggt atgctagtag gaagagagat ccgcaaagtt
     2041 tcaagtactg tgccgattat catgctgaca gctagagatt ctgaaagcga tcaggtgatc
     2101 ggcttagaga tgggggcaga tgattatgtc acaaaacctt tcagtcctct gacgcttatt
     2161 gctcgaatga aagctttgca tcgccgtagt gagttggcag aagcaagaga agaagcagta
     2221 gtttcagatg atcattttga tatcgagact agtcatttca agatgaatac gaaaacacga
     2281 gaagcgtatc tggacaaccg gccaattgaa ggactgacgc ctaaagagtt cgatctattg
     2341 tttactttag caaaaaaacc acgtcaagta ttctctcggg agcagttgct tgaattagtc
     2401 tgggattatc agtactttgg tgatgaacgg acagtggacg cccatatcaa gaaattacga
     2461 caaaaaatcg aaaaggtcgg accacaagtc atccaaactg tttggggagt cggctacaaa
     2521 ttcgatgatt ctggtgttgc ctaatgcgtt atttgtatca gcaactctta gctttctgcg
     2581 gaatggtcgc gttgatctta ttgatcgttg gagtttcttt tacacaactg acaaaacaaa
     2641 cgattgaaga aaacaattac cagcaactgt ttggatatgc tgaatcagtt gaaaagacaa
     2701 cgcaaaccta tgccgatacg ctcccgcagt ttagtcaaga tcaggcgttt caaaatgcat
     2761 tgctgctgac agagcaagta ctgacagaac aaaatgtgaa ctttatattt atcgataaaa
     2821 acgaacgtgt catttatccg actaatacag ctttactgaa ttttacctta acagctgatc
     2881 aatggaaaaa tctgaggaat ggacgtcaag aaaaattcac atcgaataaa aatattttag
     2941 gacaagcaca ggcgacctct tacgcacttg tgccatttaa tttgaatcat gaattctatg
     3001 gagcacttgt agttagtcaa cctgcgcgaa atatcgataa cagcgttcgt ccaattacac
     3061 tgaacctgtt caaaggattt attttttcca gtatcgttgc agttattgcc agctatgctt
     3121 ttgcagcatt ccaagttaag cgtatcaatc ggttaaggaa tgcgacgaaa gaagtgacga
     3181 atggtaattt tgatgtacag ctccccgtac atgacaaaga tgaatttgat gagttagcag
     3241 atgatttcaa taaaatgacg aattcattga aagaatctca agcagaaatt gaagaacaag
     3301 aaaatcgtcg aagacaattt atggcagatg cttctcacga gatgagaaca cctcttacga
     3361 caatcaacgg acttctggaa gggttagaat acaatgcaat ccctgaaaat cagcgagaaa
     3421 acgcgattaa attgatgaaa aatgaaacag agcgtctgat ccgtttggtg aatgaaaact
     3481 tggattatga aaaaatccgt acgaatcaaa tcagtatggt cattaaaaaa ttcaatggaa
     3541 cagaaacatt gaaaaatatt gttgcacagt tagaagctaa agcagaagca gcaggagata
     3601 cattgacatt gaaagccgtt gatgatattg atgtttacgc tgattatgac cgatttgtcc
     3661 aaatcatggt caatattatt caaaacgcga tacagtttac tgaaaacggc caaatcacga
     3721 ttactttaga aaaaggctat cttgaaacga tcatcacgat tgaagatacg ggaattggaa
     3781 tgtctgaaca acaaatgaaa agtatctggg atcgttatta taaagtagat ccttcaagaa
     3841 aaaatacaaa atatggtgaa tcaggattag gtttaccaat cgtgcagcaa cttgtacgct
     3901 tgcataaagg aaaattagaa gtagaaagcg aactaggaaa aggaacaaaa ttcgctgttc
     3961 gtttgcctga cgtagaaatc aaaaaagagt aaaaaacaag cggtataaaa gatcatgaat
     4021 cgatcttcta taccgcttgt ttttactata aaatgattga tttagcccgc gggctctaaa
     4081 cgatcaatat aaggactttg agcaatagta gcatcatgag taaagagtaa gataccttga
     4141 ttttcttcat gagctaaata agaaagcaag tggagtagct cttggatctc caatacacta
     4201 agttcatcaa atgtatcttc aataacaata ttgtttcgct tggaaagcaa ggcatgaagt
     4261 aattgcagct ttactttttc aaaagacgtc aactcagctg ccgcacaatt aagcaaggaa
     4321 ggagagatat caagtttttc ttgataggcc aaacgatctt gtttgatttc tttttccggt
     4381 acatccaaca ggacatggtc tttaagattc agataaggaa acatcggcca atttttttgg
     4441 atgatcgcaa aattatccag ttttgcaaca agaacctctt ttttcaagtg ctccaatatt
     4501 ttatgctgtt tttcgagagg acacaaaata acggtcaagt gttcagcatg aatcaaatat
     4561 tcaggtttca ttacgtccag gcctcctact ttgcaaatga tggataaaaa aagtgaaagg
     4621 gaatagacta agaatgagac agcatccact gagcccaata agagtttgag caaatccctt
     4681 aagtatatct gtgaaaaaaa gatcattttg gaaatcgatg gtaaaaaaag tctgttgatc
     4741 catcggaatt gtaagtccgc ttaccgaagt caagatatca cggatatctg gcagttcagt
     4801 agtctttaag acaagaaaat tgatcctttg aagaagcgct tcataaactg actggaagct
     4861 tacgatccac aataaaacca agatacaaca aagaaagaga ggaaagaaca gctgccagaa
     4921 aataaaaagg aataatttgg ttttagaaag accagtcagg tgccaattga tcaattcctg
     4981 cttgttttgc ctgactgaat agtaaaagaa aaagataaaa aggaaggcaa atagaaaaaa
     5041 taaactgaat atgcctttta tataaaatcg gctagctaat tctaaagccg gaagaagctc
     5101 tgtagatgca gaagcgccaa taaatgaaag ccgatcttgg acttgattgg ctaaagccga
     5161 ttgcaaatgg taaagagtca ggcatgctat caataaaaaa gcagaaaagc ttgaaaataa
     5221 acaatagagt attgtctgct ttttgtaata aattaatcga gcagtagcat agcggattat
     5281 tttcatactt ttcacctcta taaaaagtat agaaaatgaa tatgaataaa gtatgaaatt
     5341 cctttagtga aatcacgaat taaaaccaga aaatattttg taaaaagcaa gaggttgtga
     5401 agaagctgcc ctattctatt accgtagatg caagcttttg aacactgttt attcgaaaag
     5461 aggagcagcg acaataattt tgggctcttc gtcaatgagt gttggtgaag aaattcaata
     5521 gaataatcga gatactcaca cggctagaca gctatcttgt ctagccgtgt tgttgttctg
     5581 gctttagtca gttgggtagt gttcttagtt ttcttgaaat attttcctcg atataaaaag
     5641 attcgttctc ggtagttttg aaagtttcta aagccatagg caattcgttt tagtactttg
     5701 atatggttgt tcaaacattc tatagggccg ttggaatagg gaactcgcaa cgctcgtttg
     5761 atttctgttc gatatttctt gaaggtcgtg aacactggtt gatagtgctc tggcaactcc
     5821 ttgtagtctt cttttaggag cgcgacgaat tcaggaacat cttgtcttct gatagcggaa
     5881 agaaaaacct ggtagacttc gtagcctcgc tttaaggagt catcataata taatagccga
     5941 tcgactatct ccgcttctgt cagatgatct cgaaatgacg gacgccagta gcgatgctga
     6001 ccattcaatt cccacgcatt cttttgaagt agtctccagt atttctttaa gtgcttcgac
     6061 cgacgatccc cttttttaaa ggtcttcatt acttgaattc ggtggttggt aaaggcccga
     6121 ccgatgtgtt ggctaatatg aaagcgatcg gcgacgattc gggcattcgg aaaacactct
     6181 ttcaccaatg tgcgataggg tgtatagaaa tctgaaacca ctagacgtac ttgttcacgg
     6241 acttttctag ggtagcgcaa gaaatagtcg cgtaaaggat tgagttgccg attttccaca
     6301 atatcaatca gttgatgggt cttgccgtcc atcatgacaa agctcatggc tcccgagacg
     6361 tttttcaccg atttgaattc atcgaaacac accacttctg gtaacggctg gttcaaagaa
     6421 acggttttag gccgaaggct gcgaagtatt cgaatgacag tggtcggaga aatgtgcttc
     6481 atacgtgcaa tcaaagacat agaaataggc tcacttaata gctcaagaat ggcttgtttg
     6541 actctgcggg caatggagca gcgacgatcg ctaactgaat cttctgctaa aaaagtcttt
     6601 ccacagtgtt tacatttgaa gcgctgtttg ttaatccgca caatggtctt gtagttactg
     6661 acatcattca ataagatgga tacttttttc cagccccatt taatgatcgt ttgcttattt
     6721 tgatagtggc aatggaagca ttcctctggt tgataggtca atgtgccatc aaaaacaaaa
     6781 catgtttcgt cattaatgcg ctctttgcga aaggcatctt catgaaaggt aagatttagg
     6841 tctagaatat ctagtaactc tttggtaaac tctgaatagg acatcttgaa acactccttt
     6901 gaatggtttt cgtcgacttt attctaaagg atttcaaggt gtctgtttgc gtttattaga
     6961 aaaaagaaaa agtattggca acagaaggcg tcaccaacac tagatattat agatcctaat
     7021 tttgtcgctg ctccttttaa atttatttta tcattcggaa gaacttgtgg tcgttccgtg
     7081 aagttcttgg tacgtttgcg ttttataaag atcaacagtt gattgtccgt tgtgttcact
     7141 aaagacacta gttgacttgt caccaagaga tttttcagct tcttttaatt tctctaagcc
     7201 attcttgtag tcataatcac tggtatcaat tgggtctaat ccactattcg tatagaaccg
     7261 aagaagatca ccattattga tttggtcaga aacagctaac tgtttatcaa ctttttcttt
     7321 cagtgaatca atttcattct gtacttcctc agtaggttca gtaatagctt caccagtttc
     7381 gttactatag atcgtaccac cgtagtaagt atattttggt gtaacaaaat caccatcacg
     7441 gaaagaaaca agctgttcat gatctttcga gaatagatct tgtcctaact gaatataatt
     7501 ttttgtatct acacctagta agtgaagtaa tgtaggcaag gcatcaactt gtccgccgta
     7561 agtgtgattg attccgccct gtgtttgtcc agggatatgg atcatataag ggacacgctg
     7621 catttgtgca ttgtcgtagt ttgtccaagt agaacttgtt tttccaacta attcagctag
     7681 atttttattt cttgaattcg agacaccgta atggtcaccg taaaggacga tgactgaatt
     7741 atcatacaag ccgctttctt tcaaataatt gaagaattct tgtacggcgg tatctaaata
     7801 attggctgtc gcaaagtaac cgttgatcgt ttcatcattt gtattggcta acgggaatcc
     7861 tgcttcgtca ttggtgaatt ttgaataagg ataatggtta gatacagcaa tgaattttga
     7921 ataaaatggt tgttgcagac gttccaagta ttgtacggat tgttggaaaa atggtttatc
     7981 atgcaacccg tattggaacg aattgtcatc attaacatca taataagaag aatcaaagaa
     8041 ataatcatat cctaaattct tgtatgtctc gtttcgattc cagaatgtac cagcgttccc
     8101 atggaatacc gcactaatgt aaccttgtgt ttgacttaaa atatcaggtg cagcttggaa
     8161 agtatttttt ccgcctaatt gtgtgaacaa ggagccttga ttcaagccaa acaatgaatt
     8221 ttccatcagc gtttccgcat cgcttgtttt tcctgctttt acttgatgga aaaagttgtc
     8281 aaaactgaac gtgctgttgc tgtggtaaag actattgatg aaaggtgtaa cttcatgctg
     8341 gagaccattc tcatctgtca atttataatc gatcaggaat tgctggaagc tttctaaatg
     8401 gatataaatc acattttttc ctctagcgag cccgaacaaa tcgtcatttg gtgctgcata
     8461 atgttctttt acataatttt ctacttcttt catatcattg ggacttgctt ctgcccgcac
     8521 ttggtttgtc tggtaagttt gaacaccgtc ataaaccatg aaagcattca agccaagata
     8581 tttgaccaaa taatcacgag agaatgttcg agtcagcaat tctggacgat cagcttccgc
     8641 cataaaaaga tttcctgaga aaatcataac tgctaatgta gagatcgcaa aagccattct
     8701 tgctcggatc gggcgagggt ccaacttgat tttttttgca atcagcagaa cagtcaagat
     8761 aataaaatcg atccaataga tcacatcata tgggcgaaac agtcgaatgg cactttctcc
     8821 cagaccactc gctactttcc cagcacctaa aatcgtgttg atcgtaatga agtccgtgaa
     8881 ttctcgataa taagtgacat tcgaaaaaac aagcaatgtc aaaagaaaat aaatgaccat
     8941 catcgtgata taagcaactc tagggcgtct gatataaaga gcaattccaa gtaataacaa
     9001 tgtagttgca atagggttga taaacaagat aaagtattga atgccacttt cgattccgag
     9061 atggaaatca actaaatagg caaaaatcgt tttcaaccaa agtaaaacga ctagtaaaga
     9121 aaaaaatccg agcctcttat tcaaaaaggc aggtgttttt atacatttca agataatctt
     9181 cctttctgca cttcttaatc acagaagtgt cctgaaacca tgttacacag ctcacttatt
     9241 ctcatttatt ttactagtat gacaatatag tgtcaattga aaccagaagt ttatgctgtt
     9301 tcattaaggt tttctttaag cttcatgaaa aaatgagcag taagacaagt cctatgtttt
     9361 ttgttatact tgggaagaga aagctaaagc aggtgaagga atgaaagtaa aagtaaaaaa
     9421 aagagcaagc aatcgattga aaaaaggata tccactgatc caaaaagaag accttgctca
     9481 tccccaaaaa gaaaccacgc aatgggtgga attagttgat tcgcaaaacc aatttatcgc
     9541 aaaaggatat ctaggaaagc agaataaggg aatcggttgg gtattgagcc agcagaacat
     9601 cccatttgat caatcttttt ttgaagaatt ttttgtgaag tcaaaagaaa aaagaacttt
     9661 ctttttttca gatgattcta ctaccgcttt tcgtatattc aatggagaag gagacgggat
     9721 cggcggtctg attgttgatt attatgcagg ttatgctgtt ttttcttggt ataacgaaac
     9781 gttatatgca catcgtgaat tattgattca agcttttcgt gaaatctacc cggaaatcat
     9841 aggaggctat gagaaaattc gatttgaatc agtaaatctg cctgagagcc agttcattta
     9901 cggaaaagag gcaccggaac ccttgatcgt aaaagaaaac ggagtaaaat ttgccgttta
     9961 tttaaatgaa ggattaatga ctgggatctt tttagaccaa aaagaagtac ggggatcatt
    10021 agcagaaggt ttcgcttctg ggaaaacagt tttgaacatg tttagttata ccggcgcctt
    10081 ttctgttgct gccgcaatgg gaggggcaat cgaaacaaca agtgtcgatc tagcaaaacg
    10141 cagtttaaaa aaaacacagg aacagtttga agtgaatggt ttggatgtcg atcagcaaaa
    10201 aatcattgtt atggacgtat tcgagtattt caaatacgcc aaaagaaaac aatttttata
    10261 tgacatgatt gtattggatc caccaagttt tgccagaaat aagaaaaaag tctttcgcgt
    10321 agcaaaagat tatggggaac tggtcaagga tagtctggat attttagcag aagacgggat
    10381 acttattgcg tctacaaatg ctgcgaatgt ctcgatagaa caattccaaa caatgattga
    10441 agaggaattc catgccaaaa atgtttcttt tgaacaactt gctttatatc gtctgccaaa
    10501 agatttccag acgacggata cctttttaga aggcaattat ctgaaagtgt ttgtttatca
    10561 aattaaaaat aaccattaga aggagcgatg cagaatggtt cgggtaaagg gattgaatat
    10621 aggaagcggt agaccaaaga tttgtgcgcc tcttatcggg gccgtccgag aggaagtatt
    10681 acgtgaagca gttcttgcac gtgaagcagg ggccgattta gtcgaatggc gagtcgatca
    10741 ttatcgtgaa gttttttctt ttgatgaagt agcagaaaca ttggttctta tccatgagat
    10801 gcttgatgga ctgccgttat tatttacgtt tcgtacctta gctgaaggcg gagaacaaga
    10861 catatcgatc cgtcagtatc gcgaccttta tgaacatgtg atacacacag gattagtaga
    10921 tatggtcgat atcgagttgt tcaaagtaga aagtctagga aaaagactga tagaggaaat
    10981 caagtcttta aacattcctt taattatcag tagtcatgat tttaaagaaa caccagcaga
    11041 ccctgtcttg ctttaccgat tgaatgttat ggaacatttt ggagccgata tcggaaaact
    11101 ggcagtaact cccaataatg aacgagatgt tttgcggttg atggagttga ctagacgggc
    11161 aaatgctttt ttctccatgc ctattattac gatgtccatg ggaaatcttg gtaaaatttc
    11221 tcgtctggtt ggcggaacga cgggttccgt tatgacattt ggttccttaa gcagcgattc
    11281 tacttctgct ccaggacaat taccggtcaa agcattgaag caaattattc aattattaaa
    11341 tgaaccgttg tagaacaagt ttgaggtgat attttttggc aaagaaaaaa atagtaaaaa
    11401 cgaatgcaat ccgtatggtc gaacaaaaaa agattcccta tacagagcac gaatatgagt
    11461 gggacgaaag ccacctaagt gcgtcatcgg tcgctgaaca gcttccagaa agccaatctc
    11521 gtatatttaa aacactggtt gctgtgggca atgtgacggg gcctcttgtt gctgtgatac
    11581 cgggagaagc cgaattgaat ctaaaaaaat tagcaaaagt ttcagggaat aaaaaagtag
    11641 aaatgctcca tttaaaagat ttggaagcaa cgaccggata catacgtggt ggctgctcgc
    11701 ctataggtat gaaaaaacta tttcctactt atttagatca aattgcagaa agctatgaac
    11761 aaatcattgt ctcggctggc agaagagggc tacagatgga gttagcacct caagatatct
    11821 gtgcattaac gagcggacaa tttgcagata taaaacaata aatcatacgt ataaaagaaa
    11881 gaaggaggcc gggatgttgt ttgtccagtc tccttctttc ttttttatac attatgctct
    11941 ttgcccggca ttcattcctg ctacatgccc tgtagcgaaa gccgctgtga tattaaagcc
    12001 gccagtataa ccattgacat ccagtaattc tcccgcaaaa tacagaccat caatgatttt
    12061 actctccaat gttttaggat aaatttcctt tagagaaacc cctccgccag ttacaaatga
    12121 tttctcaata ggaaaagttt tgttgattga tagcttaaac tctttgcata gttgaacaaa
    12181 atcttgaatt tgtttttgag aggcttgttg tcctgtcaga tgatccattt caagccgctc
    12241 aagaaagaaa actaacaatc gctcaggcaa tataccatgc caagcattga ccaagttctt
    12301 tttggttgct ttactttttt ctgtcaatat atgaataagc tcttgtttgg tttgtgtagg
    12361 gaaacaatcc agagaaagtg tcactggttc tcccgttttc tctaattctt tattgacaaa
    12421 acttgaacaa cgcagtgcag ccggaccaga aataccgaaa tgggtgaaaa gtaaatccat
    12481 cgtatgttca gtcaatacac gacctttttt atttaaaacg cgtaaagtga tgtcttgtaa
    12541 agaaagccct tgaagtgttt tctcctgaat atacggttca tccgatatca agggggactc
    12601 tgtcgcataa agaggcgtca ccgtgtgacc cactcgcttc acgatcttgt acccatctcc
    12661 agtagaacca gtagatggat aagtccgtcc accagttgtt aagataatgg caggagcatg
    12721 gaactcttcg aattccgtgc gtataccgta aattttatgt tctttgtgga tcaatttctc
    12781 tactcgagta gagaatagaa gcgtcacatc tagttctttc agacgattga gcaatgcttc
    12841 gataatcgtt tttgatttat ttgttacagg aaacatccgt ccatgatcct cttcttttaa
    12901 atgtacgcct tgtgattcaa agaagttcat gatatcgaaa ttattccatt gcgcaaacgt
    12961 actatataaa aactttccat ttccaggaat atgtgcaatc aaatcatcaa caggacgatt
    13021 gttcgtaaca ttgcaccgac caccacctgt catcagtagt ttttttcctg cttttttgtt
    13081 tttttcgatc aagagtacgc gtgcgccttg ttcagctgca ctgatcgctg ccatcatccc
    13141 gcttgttcca gcgccgacta cgatcacatc atacagtttt tccattccct cacctcaagg
    13201 aaagtgtagc atatctgaag aaagaaaaca gaaaaaaatg ttttgagcca aaagagaaaa
    13261 tgagctaaaa tgagggaaga taagcaaagg agcgtggaac gatgacaaac gcaacagaat
    13321 atgttcaagc aattcaagaa aagctacatc aaaaggatca agggcaagaa gaatttttac
    13381 aagcaatcga tgaattcatg cccacggtta tgtctttttt ggacactcat cccgaatata
    13441 tcgaaaagaa tatcttagaa cttttaacgg aaccagaaag agttattcaa tttcgagtgc
    13501 cttggcaaga tgatgaagga aactggcgag taaatagagg gtaccgtatc caatacaact
    13561 cagctatcgg cccttataaa ggtggattgc gcttccatcc tagtgtcaat ctaagtatct
    13621 tgaaattttt ggcttttgaa cagattttca agaatagttt aaccggtctg ccaatcggtg
    13681 gaggaaaagg cggaagtgac ttcgatccta aaggaaaatc tgataatgag atcatgcgtt
    13741 tttgtcaaag tttcatgctg gaattgtcaa aacatatcgg cccatcgatt gatgttcctg
    13801 cgggagatat cggtgtagga gctagagaaa tcggctattt gttcggcgaa tataaacgat
    13861 tgaaaaaata tgatactggt gtgttgacag gtaaaccttt ggatttttgg ggaagtaaga
    13921 tacgtacgga agctactggt tatggattag tgtattatgt caaacatcta ttgaacgaag
    13981 aaaaagattc atttaatcaa aaaacagttt ttgtttccgg aagcgggaat gtagccattt
    14041 atgcaatcga aaaagtgcaa gagctaggcg ggaaagttgt tacatgttca gattctagcg
    14101 ggtacatcta tgatccagaa ggaatagatg tgaaactatt gaaagaagtc aaagaaatca
    14161 atagacaacg tttgacggaa tacgcaaacc aacgtccttc tgctatttat catgctggag
    14221 aatctgtttg gacattgaaa gaaaaagcgg atatcgcttt gccatgtgct actcaaaatg
    14281 aaatagacga aagcttggcc gaaatcttag tagaaaatgg gatcaaaatc gtagcagaag
    14341 gcgctaatat gccatgtaca gtaaaagctg tttctgttct tcatgaagca ggcgtgtggt
    14401 attgtccagg aaaagctgct aatgctggag gagtagcagt atctgcttta gaaatgagtc
    14461 agaacgtcca gcgattgact tgggaaagag agcaagtgga tgagcagctg gatcaaatca
    14521 tggaaacgat ttaccatacg tgtcgccaaa cagcagccga gtacggcgac gaaaaaaatc
    14581 tgcttcttgg agcaaatgtt gctggatttg aaaaagttgc caaagcaatg gcagcagaag
    14641 gtttagtttg aaaaatgaaa ctttcttgga aatattgtca gcattttgtt tatttgcttg
    14701 aaaaataata aaaaaaaacg taaagtatta cctgtagagt aaacctataa ggaggagaac
    14761 aaatggcaca cattcatttt gactattcaa aagtagcacc gtttgtcaac gaacaagagt
    14821 tagggtacat gcaaagccaa gtaacagcag cccacaacga attacgggaa ggtactggcg
    14881 caggaagcga cttccgcggc tggatcgatt taccaacgaa ctatgacaaa gaagaatttg
    14941 cacgtatcaa agaagcagct aaaaaaatcc aatctgattc tgaagtatta gttgttatcg
    15001 gtatcggtgg ttcttattta ggcgctcgtg cagcgatcga cttcttgaat cacacattct
    15061 tcaatttatt agatagcaac acaagaaaag caccacaaat cttctttgcc ggaaattcaa
    15121 tcagctcaac atatattgct gacttgatcg aagtaatcgg tgatcgcgac ttttcagtaa
    15181 acgttatttc aaaatctgga acaactactg aaccagcgat tgcgttccgt gtattcaaag
    15241 agcttcttgt taagaaatat ggacaagaag aagcaaacaa acgtatctac gctacaacag
    15301 ataaagcaaa aggtgcagtt aaagtagaag cagatgcaga aggttgggaa actttcgtga
    15361 ttcctgatga catcggcgga cgtttctctg tattaactgc tgttggtttg ttaccaatcg
    15421 ctgttagtgg tgcagatatc gatgcattga tgcaaggtgc cgctgatgca agcaaagcat
    15481 actcaagcga caaactagaa gaaaacgaag cttaccaata cgcagcaatg cgcaacattc
    15541 tttaccgtaa aggcaaagta actgagttgt tgatcaacta tgaaccagga atgcaatact
    15601 tctcagaatg gtggaaacaa ttgtatggtg aatctgaagg aaaagaccaa aaaggcatct
    15661 atccttcaag cgcaaacttc tcaactgatt tgcactcttt aggacaattc atccaagaag
    15721 gacgtcgcaa tatttttgaa acagttgtga aggttgaaaa acctcgtaaa tcaatcacaa
    15781 ttcctgaaca agcagaagat ttagacggtc taggctactt gcaaggaaaa gaagtggact
    15841 tcgtaaatac aaaagcattt gaaggaacat tgcttgctca tacagacggt gacgtgccta
    15901 acttgctagt caaaattcca gaaatggatg cttatacatt gggttataca atgtacttct
    15961 ttgaaattgc tgtaggtatt tcaggttact tgaatggaat caacccattc gaccaaccag
    16021 gtgtagaagc ttacaagaaa aacatgttcg cacttctagg caaaccaggc tttgaagatc
    16081 ttgctaaaga attgaacgaa cgcctgtaag ataagggttt ttcgctagat ttaaataatc
    16141 agtgatagaa acatgttcgc tttaaaatga aaactggtac ccatttaggt actcaaacat
    16201 actgcatcgt ttattcagaa taaggggctg tgacaagacg tttgtcacag tcccttgttt
    16261 gtatagaaat cgattgattg ccttgctctt tagtttgttt taggacttta agaacagtga
    16321 ggctgacttc gaaggttaat tctgtttttt tgttttctag aatcagtaag caaaaaagca
    16381 ctcacttcga gtgctttttt gcgatatatt cttagcttaa gataggccta atttttcttt
    16441 tacagatgag ggtaccttat cgctggtaat tacttttttc tctatgatcc gcttttcgct
    16501 tgctttcaac tgcaagatcg ttccttcggg gtaagcagaa ccattggcag agtcaccaga
    16561 agtaatgaca tcgaaatcta actgtctttt ttcaccgttt tcagcataag catctacgtt
    16621 gtatttaaaa cctcttccaa ttacttcccc attatctgct ttgatatcag tttctgcagg
    16681 cattggagct ttgactaccg cataataatc tttacctaca taagtagact gatagtagtc
    16741 ccaacctttc catcctataa aagcaatcaa tatgataacg atcaacccta aaattttttt
    16801 catgaaagat ctcctttttt attttta
//
LOCUS       DAFEEZ010000063        16528 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000063
VERSION     DAFEEZ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.066"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(142..417)
                     /locus_tag="LP245_002216"
     CDS             complement(142..417)
                     /locus_tag="LP245_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBL1520110.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(660..1970)
                     /gene="der"
                     /locus_tag="LP245_002217"
     CDS             complement(660..1970)
                     /gene="der"
                     /locus_tag="LP245_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBL1520111.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(2152..3381)
                     /gene="rpsA"
                     /locus_tag="LP245_002218"
     CDS             complement(2152..3381)
                     /gene="rpsA"
                     /locus_tag="LP245_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBL1520112.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(3516..4196)
                     /locus_tag="LP245_002219"
     CDS             complement(3516..4196)
                     /locus_tag="LP245_002219"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBL1520113.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(4245..4880)
                     /locus_tag="LP245_002220"
     CDS             complement(4245..4880)
                     /locus_tag="LP245_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL1520114.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(4946..6349)
                     /locus_tag="LP245_002221"
     CDS             complement(4946..6349)
                     /locus_tag="LP245_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBL1520115.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(6336..7367)
                     /locus_tag="LP245_002222"
     CDS             complement(6336..7367)
                     /locus_tag="LP245_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1520116.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            7398..7619
                     /locus_tag="LP245_002223"
     CDS             7398..7619
                     /locus_tag="LP245_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBL1520117.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(7784..8521)
                     /locus_tag="LP245_002224"
     CDS             complement(7784..8521)
                     /locus_tag="LP245_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBL1520118.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(8674..10014)
                     /locus_tag="LP245_002225"
     CDS             complement(8674..10014)
                     /locus_tag="LP245_002225"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBL1520119.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(10251..11774)
                     /locus_tag="LP245_002226"
     CDS             complement(10251..11774)
                     /locus_tag="LP245_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBL1520120.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(12152..12763)
                     /locus_tag="LP245_002227"
     CDS             complement(12152..12763)
                     /locus_tag="LP245_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL1520121.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(12886..13011)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13093..13809)
                     /locus_tag="LP245_002228"
     CDS             complement(13093..13809)
                     /locus_tag="LP245_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBL1520122.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(13815..14384)
                     /gene="scpB"
                     /locus_tag="LP245_002229"
     CDS             complement(13815..14384)
                     /gene="scpB"
                     /locus_tag="LP245_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBL1520123.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(14368..15165)
                     /locus_tag="LP245_002230"
     CDS             complement(14368..15165)
                     /locus_tag="LP245_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBL1520124.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(15135..15506)
                     /locus_tag="LP245_002231"
     CDS             complement(15135..15506)
                     /locus_tag="LP245_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL1520125.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(15525..16412)
                     /gene="xerD"
                     /locus_tag="LP245_002232"
     CDS             complement(15525..16412)
                     /gene="xerD"
                     /locus_tag="LP245_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBL1520126.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         4645 a         3577 c         2798 g         5508 t
ORIGIN      
        1 taaaaattaa ataaaataca tgtgttttct atgtatgaca tacggattcg gaatctctgt
       61 ctcttattta ttccttttct gctaggaaat aaaaagaaaa gcacttgtag ccctagagcc
      121 acaagcgctt tttcaactgt cttatttaac agcgtctttt aatgctttac ctggtttgaa
      181 tgcaggtact ttgctagctg gaatttcgat ttcttcacca gtttgtgggt tacgaccttt
      241 gcgagctgcg cgttcgcgaa cttcaaagtt accaaaaccg attaattgaa ctttttcgcc
      301 gttagctaaa gcatcttgaa tagttgaaaa tacagcatct actgctgcag ttgcatcttt
      361 tttagttaaa tcagtagctg aagcaacttt ttcgattaat tctgctttgt ttgccatgga
      421 tagattcacc tcctccacaa gagatatgat agaaatatca tttagttaaa actttctgag
      481 tggtccagaa gtttaaaaag aaatattgat taacttcaat attctgttat cacgatatca
      541 tatgaaccgc ttaatagcaa ggtttttacc aattttcaca tgcttttttt agtcatagaa
      601 acgtaacaaa cgaaactgtc tttttctttt gaaaaaaaaa cgtcgatatg gtaaaatgcc
      661 tattttctcc tacgagggat aattcggatg gacgtccctt caaaagtaaa tgcttttctg
      721 atttgatttt ctaagaaacg ttcataagaa aaatgcatca attcctcttc attgacaaaa
      781 acgacaaatg taggtggttt gacagcgact tgtgtagcat aaaaaatctt caggcgtttt
      841 cctttatctg ttggtgttgg attgattgct acagcatcca taatgatatc attcaacaca
      901 gccgaagaga tacgaagatt ctggttcata cttacttgtt cgatcatttc aggcagacgt
      961 tccaaccgtt gtttagtcac tgcagaaaca aaaacgattg gagcgtaatc aagataccgg
     1021 aattcatcac gaatctcttg ttcgaaatca cgcattgtat tggtttcttt ctttacaaga
     1081 tcccatttat tcacgacgat aataattcca cgaccagctt catgggcgta acccgctact
     1141 cgcttgtctt gttcccgaat cccttcttca gcattcagta ccatcaaaac gatatcagaa
     1201 cggtcaatgg cacgcattgc acgcatcacg ctgtattttt cagtattttc gtatactttt
     1261 ccgcgtttac gcataccagc tgtatctatc attaagaatt tctgaccact ttcagaaacg
     1321 aagtgggtgt cgattgcgtc tcgggtcgtt ccttcaatat ccgaaacaat tacacgttct
     1381 tctcctaaaa tcgcattgat caaagaggat ttaccaacat ttgggcgacc aatcaaacta
     1441 aacttaatcg tgtcgtcgtc ctcttcttca gtctcttcag agaaatactt cactgcttca
     1501 tctaaaatat caccaatccc tagtccatgg cttcctgaaa caggataagg atcgcctagc
     1561 cctaaggaat aaaattcata gatatcgttt ctcatttctg gattatctac tttattgact
     1621 gctaaaatca ctggtttatt acttctgtat aaaattttcg caaccatctc atctgcgtct
     1681 gtcacgcctt cgcgtccgct gactacacaa atgattacat ctgcttcttc aatcgcgatt
     1741 tctgcttgat gcttgatctg atccataaaa ggttcatcgc caagatcaat tccgcctgtg
     1801 tcgatcacgc tgaattctcg acctaaccat tcaccttttg cataaatacg atcacgagtt
     1861 actccaggag tatcttcgac aatcgagata cgctcaccag cgatgcggtt aaaaatcgta
     1921 gacttaccga cgttcgggcg gccaacgatt gcaattgttg gatttgccat attatttcct
     1981 cctcacaagt ttccaatctc acttagttta acgaatgcat tgccaacttt caagcataga
     2041 ttgtcaatta aacgaagtat ttttattcct tattgaaata ctaatcgctt ttcaaaagaa
     2101 aaactgagac aaaagcagct gctttcatct cagtcacaga tacaaaatca attatttttc
     2161 agaatcatcg gttgcttttt cttctacttc ttctttcaac gcatcaccta aaatgtctcc
     2221 catagtaaat ccagtatttt cttctggtaa ttcataagac tcaacatttt ttggttcttc
     2281 ttctgaagct ggtttttctt ctaaagcttt gatactcaat gcaatacgat gttcttctgg
     2341 atggatctct aatactttca ctttcacttc gtcaccttca tgaagcactt catgtggtgt
     2401 cgcaatatgt ttatgtgaaa tttgagagat atggactagc ccttctactc cagggaacac
     2461 ttcaacaaag gcaccgaagc ttgtcaaacg tttaactgtt ccgtctaata ctgtgccaac
     2521 tggagctttt gtatcgattt ctgaccaagg tccaggctgt gtgtctttga ttgacaagga
     2581 aacacgttct tgttcaggat tgatagacaa cactttgaca tttacatcat cattgacagc
     2641 caatacatca cttggttttg ctacatgact atgtgaaatc tctgagacat ggactagacc
     2701 gtcaattccg cctaggtcga caaatgcgcc aaaatcagta agacgtgcaa cacgtccact
     2761 gagaacatct ccctcatgga tagttgaaag aatttctttt ttcttttctt ctctttcgtt
     2821 ttccactacc gctttatgcg ataagatcaa acgattttct gatggttcga tttcgatgat
     2881 tttaaagctc aatgttttgc ctttatagtc tgaaaagtct gcaacaaaat gatcttccac
     2941 cattgatgca gggacaaaac cacgtacacc gacgtcaacg actaaaccgc ctttgacaac
     3001 atttgtaaca ggtgcttcga tgaccttgcc ctcttggaaa tctctttcga tatcttccca
     3061 aactttttta gcatctaaac ggcgttttga aagtaggtag ctgccgtttt ctttatcttt
     3121 gccgatcgta ctgataacga ctaaatctaa tacatcaccg acttttacta cttcgctgat
     3181 atcttctacc ggcaaagttg ataattcttt tgccggaacg actccttcaa ctccagcccc
     3241 ttcgattccg acaatcactt gtttgtcttc aatgactaaa acttcgccct taacaacatc
     3301 gccaactttt acttcttgta cgcttttcat tgcgtcttcc attgactggt tgttctcttg
     3361 attttgatca aattctgtca taacacttgt cctcctaacc aacattctgc cgtaagtacg
     3421 gtactgtttt tagtttaatt gattattcaa aaaaaataaa gcgatttcgt tcgttttcct
     3481 tgaaaaaaca attgtttttc attttttttc ttaatttaaa aaagaagata accttttttc
     3541 aaaacaacag cttttattgc tgcaacgact tctggaatcg atttgccagt cgtatcgata
     3601 cgaacagcat cctctgcttg cttcagcgga gagacgtccc ttgttgaatc ataatggtct
     3661 ctttcctgta tctctttcgt cagtgtttca agatcagtcg gaattccttt ttcttggttc
     3721 tctttgaaac gtctttctgc acgctcactt acgcttgcta ctaaaaagat tttcacttct
     3781 gcattcggta atacagctgt cccgatgtct cttccgtcca tgacaacgcc accgcgttcc
     3841 cctatttttc gttggacagc aactaattct tctctgactt ttccatgtgc agagacttca
     3901 gaaacagctt ttgtgacatc tggttgacgg atttctaaag tcacatcttt tgatgctatg
     3961 aatacatgct gtccatcttc ttgttgcgaa aaagagatag gatacttttt gatcagcgaa
     4021 actagccctt cttcatctga aaaagataca ttgttcgtaa tagctaaata agttactgcg
     4081 cgatacatgg caccggtatc tgtataaata taattcaatt cttttgctaa tatcttggca
     4141 acggtacttt tcccagatga agcaggcccg tcgattgcaa tactgatttg tgtcatgata
     4201 taactccttt ttctcagaaa aaaagccgca aagcgcggct attattattt aattcttaat
     4261 tcttgaccag ggtaaagcat aaagttgttt ggatctaagc cattcaattc aaacaattga
     4321 tcagtggtga tccctgcacg ctcagccact tgttttggac cttcgcctgc ttgaacagtc
     4381 gttgttgaac cggctgcagc tgatgaagaa ggtgttgttt ctgctgcatt gctgcttgaa
     4441 tcccctgctt gataagttgc ctcacttgag gaagtcggtg ttgtctctgc tgcaatactg
     4501 ctttctgacg ttacacctgt atcttgagac acagtagatt cttccgcgat tgtactagat
     4561 tctactgttg aagtctcagt tgactcctct tttgttgtac ttgtagaact ttctactact
     4621 gatgtcgaag tttcagaaga agttgctgct gttgcattgt tgcttgatcc atttctgatc
     4681 cagaaataag cacctgctgg aatagcgata cataagacca gtaaaatcaa aaatagcgaa
     4741 agaaataatg tatttccttt cttttgttgt ctctgagaac ttcttgatga aacttcatca
     4801 tctgtatcgt agattggttg ttcccatggt tcttgtgttt cgttattttc tgtagattga
     4861 tgtctatctt ttctgctcac tgttttacct cctaaactct atcgtgtgta ttataccata
     4921 ggaaaaagtg tcttgtccta aaaaatcaat gttccatgtt ttttttaaat aaatttagta
     4981 aaatcgtttc ccaatgaagt tgttcagtct tagaaaaaag cttcctcttt ggcagaagtt
     5041 ctgcttttgc tccatcaata tcacaacaat tctgcggctt ttcggagagt ttttcgccaa
     5101 aataagctaa gatgaatttt ctgcggcagt tttcttcatt aatatagcga agcatctgct
     5161 gcaggcggaa ttctttttct ttttcctgac gtttgagccg ttccacccaa ttttctggtt
     5221 tttcagactg ctggatcagc tccatccatt ttttttgcag ctcatcaaag ggagcttgct
     5281 ttgtggcata ttccaaataa agctcaaaac tttgtcgctg ttctctagaa agttgattaa
     5341 agaaataatg gatacgttca tccccacttt gataaaaaag aattgctgca ctttcttcct
     5401 gatctctgcc tgctcgaccg atttcttgta catagttttc tagactgtct ggcaaatcat
     5461 aatggaccac ataacggata tcagatttat cgatccccat accaaatgca ttcgtagcaa
     5521 tgagaaactg cagctgattt tttacaaact gctgttgaag ttgtcttctt tgagctgcat
     5581 caagaccacc gtgatagtat ccaactgtaa aacgttccct gaataaatga tacaatcgtt
     5641 cgacttcttt ttttgttgca caataaatga ttgccgctcc ttgtgctctt tccatgaagt
     5701 gttcaagttc ttgttctttt tgctgcgttt tccgaacaaa aagcgagata ttttgccgat
     5761 tgactgattg tctgatctct tttggtggtc gatcaaatag tacatgacgt atatctcttg
     5821 ctactaaatc tgttgctgtc gccgttagtg ccagtgtgac cgggtttcct aaaagctttc
     5881 ggatttttcc taactgttga tattctggac ggaaatcaac tccccattga gacacgcaat
     5941 gagcctcatc tactacatat aacgcaatat tttgtttttt cagatgctct aaaagagaag
     6001 gattagtcaa catttcggga ctcaaaaaca aaaatttata ttgcgataga tgacggagga
     6061 cgtatcttct ttcagattgc gaaagtaaac tattgaaagc agctactcgt ttctcccctc
     6121 gtttttgtaa ttgcgtcact tgatcttcca ttagagaaag cagcggtgac acgatgatga
     6181 ccagaccttc cattaaatac cccgtcaatt gatagcaaag gctttttccc gttcctgtag
     6241 gcaaaatagc gagagtatct tctccatcaa gcaacgcctg aataatttct tcttggccgg
     6301 gacgaaatga atcaaatcca aaatattttt ttaattcatt tattaacatt ctgtatcgct
     6361 tcctttctca atagatagat ttgatacaaa cgaaattctc cataatctaa ttgtccatct
     6421 acattccatt cgctaaagcg ccactctcgc acggaatcct tatttggttc caaacgttcg
     6481 attgtttctg cagagagaat ccactcgtat ggaaaatcat caaaaaacaa ggcccactca
     6541 ataagatgat ctgttactgt tcctcttttt aaatgacgga ttgccatgat ctggtcaatt
     6601 gtctgaccat tcataaacat ctgcttggtg atcatcatgc tttgattgaa attttgctgt
     6661 aataatgaat cgatcaaagc gtgccaaagc gaatctggcc gtttttcgat ttgtgctaac
     6721 aaaaggtgga tacatctgct ttgttgcaga taaacctctg actcatcatt gttttttgcc
     6781 agctgataag gaagcagccc tgttcgctca tttccagata attggttagc taaaaaatct
     6841 gctgcttctt ctggtatctc cgaaaacagc tgcaccaaac tctcatacgc agtatcaatc
     6901 aaaatttcac gtggcaattg gctttcacta agccattttt ttagttggaa agtataaaaa
     6961 ggacttgtct ctgctggaag atagtcttga atacccgttg ccagattaga aattacttga
     7021 acagcaaatt taatgagccg ccaactagtt tcccctgttc tgccatagcg gtcaaaacgc
     7081 aaaccagtat gttctatttg atgttcggac aacatatcag cccctgcagg cgttagcttt
     7141 gcttcatttt catttatttc gatccaacct tgctgcgcaa ttttttgcaa aatttgataa
     7201 aacttatcct gcttcaattc tggaaaactg ttatggataa acaaaagttc gtgggtaaat
     7261 ccataaataa gtactgaagt cgttcgtttt cccacaagga gttggtaaag agaactaatc
     7321 cgcagcttgt gtcctgatga aaatagcgat aaaataaaaa caatcatatt attctcctta
     7381 agttaggatg gttagaaatg tcactactat gtaaacttgt acctgaacgc tgtattgcat
     7441 gcggtctttg tcaaatcgaa gcgccagata ttttcgatta tgatgaagaa ggaatcgttt
     7501 tatttgccca agaaccagag gctcatcaac agttcgtgat gccggaagaa gaaacatatg
     7561 taaaaaaagc gtatcaaaaa tgtccagttc gagcgatttt attagaaaat aaaatataaa
     7621 tataaacgaa actttaaaaa cgtacactaa gttctctaaa cttgaaaata agccgggatc
     7681 tgtttctctt gttccgtgaa atcccgactt attttgaaag attcatttgc tatctatagt
     7741 taattgacta gttttttcac ggaccctata ggacccattt atattatttc aactttttca
     7801 gccagttttc caatgtattg acgatcacag tttgctggtc tgcgttagaa atttctgcct
     7861 ctccatctcc tttttgctca ccatagctgc caaaacctcc atgatttccg ccattgattg
     7921 atacatactc tgttctttcc ggtaaatact gcttagcttc ttgataagct tcctgattca
     7981 atactttatc ttttgtcgcc gtgatcgata aaacaggaac agctgattct gtcaatgttc
     8041 cttttttgtc gggataactt gccatgaaga ataccccttt taaatgtttg tctgaatgat
     8101 tcttattgac ataacgactt gccattacgc cacctaatga atggccaccg atcacataat
     8161 cggaatttgg aaaatcttct ttgaccttat ccgctttgtt tccgcccatc actgctagat
     8221 caagtggcat tttgacaata gcgactgaaa agccgttttt tgctaaatct tgcgcccaaa
     8281 tactataact ttctggctct acgagagcac caggataaaa aataagtaat ggagactttc
     8341 catgattctt tttctctcct tcaaaaaata agtaatcttc tttgtttttt ccttctttta
     8401 ccaacacttg cgcttctgac gatggttcgt acgtattttg ctgtatatag taataaccgg
     8461 ctccaccgag taatcctaaa atgatgacta agccaattag tattcgtcta aatattttca
     8521 ctttctccca ccttttctat ctgagtgacc cctttttctt aatcaagtat gattatacct
     8581 taaaaaaata agagagaaat gcaaactttc cagcatcaaa taaaaaaaga cggaatatcc
     8641 atttgaatat ccgccctttt tgtatgttta tttttattta gcacataaac gatacacagc
     8701 ttctgcataa atttccattg ctttatacat actacttaat tcccatcgtt cattcgcctg
     8761 gtgcataaag tcaggagtat cagggaacat cgcaccgaat gccacacact ggttcatcgt
     8821 acgagcaaaa gtagcgccgc ctgatacaaa cggttcagtc atgtctccag taatatcgcg
     8881 atatgtcccc aatagatttt tcactaactc actgtctagt ggcacgtata atgaatcaag
     8941 gaagtcaaat tcttcataag tcaacccata tttttctgct gttttagtta atttagctac
     9001 taaatcatct ttcttgaatg taacagggat tctcatatct acaccgattt ttgtttgttc
     9061 tggtgtgatt tccaaacttg caaagttcat cgttagctcg ccggattgtt catcttctgt
     9121 tttgcccacg acagcttcac cagttgcatt ttcttgaact aattttccta agaaattgat
     9181 tgggccaaaa tcaaatactt ctgaaagagc aattgccaga cgagaaatag cattcactcc
     9241 ttgtgctgca tctttcgcgt ggatactttt accaagaacg acgatgcctt caccttgttc
     9301 ttcgaaatcg aattcgtgtt ttttcaatgc ttcttttact tcagaaagct tttctccaga
     9361 gtaaggagct gcatcaggaa caacattcaa cgctcctcca gcttttacag aaaactcgtt
     9421 cgttcctggt cctgtcaagt aagcttgcaa taagcctttt tctgcataaa ttaaaggaaa
     9481 ttcagcatct ggcgcaaatc cttgcgtaat tccttcttct ttttcgttat atttttctaa
     9541 acaacgccat aaattttctt catctgtacc aaagataaaa cgaatacgtg tcttgaattc
     9601 cacgccagca tcaatcaaag ctttgacggc atacattgcc gcaatagaag gacctttgtc
     9661 atcttgggat ccgcgaccaa ctaaccagcc gtcttttata gttggatcga atggttttgt
     9721 ttcccaatta ttttcgtccc ctgctggaac aacgtccata tgacacaaga taccgaataa
     9781 ttcatctcca gagccaatct ctgaataacc gtaatagcct tctggatctt taaatgttct
     9841 aaatcctagc ttttcactga tttccaatac tttatccaaa gcttcaatca cttttttacc
     9901 gaagggatgt ccttgtcctg aatctgcttc atctagtacg gaaggaattc ggatcaattc
     9961 gctcaatgat tctaatgctt gttcatgatg ttgttctgtc acaaattttt tcatgatatt
    10021 atcctcctaa tatgttaaaa agggtcatgt caaattcctc cgacacaacc tcttcttctc
    10081 aaataatgac gttttaagcc tgctccatca gcaagcagaa tgttcttaac aaatgatgaa
    10141 agaaaaaaca ctcactgaat ggagctattg acttgtccac gtgcttatcg atagccgttt
    10201 atcggtttct tcattcttat gatagacctt gtacctgtat ttgtctaggt ttagaacatt
    10261 gctgctacac ctaggatcac acagatggct acaaataata tcgcaattaa tttaccggta
    10321 aatttccacc acactgaaac atcgaaacga gcaattgcta cagcacccat tacgatagca
    10381 gatgttggtg taattaagtt tactaaacca gatgcagatt gataagcagt gattactaaa
    10441 tccttaccga cgccggcaaa ttcacccata ggtcccatga ttcccattgt tgcagcagct
    10501 aagccggaag ttgaaggaat caagaatgac atagggatat agaaaataaa tgtaataatg
    10561 atgaatacac ttgaagataa tgaacttaat ccttgttcgc cccaatgtaa gatggtgtct
    10621 gtgattaatc cattgttcat aaccacttgg ataccacgag caacagctac tacgattgct
    10681 acaccgatca aatcagaagc accagctaaa aattcagaga caaattcaga ctctttcatg
    10741 ccataagtga ttgctactac gatggacatt actaagaata acatagtaat ttctgggaag
    10801 taccagtcac ctaatggaag catgctttta cctagaaccg tacctagtac cggaaggttt
    10861 gttaaccagt ttgtcaatga ttcaaaaatc gtgaaattcg cattcaaggt tgtccaagga
    10921 atcaaactga tgatcatgat accaaaagta ataaagaaca atacattaac atgtttttgt
    10981 tttttcgtga ttacttcttg acgaccgatt gcttcaatat cgaaatgctt catatcttct
    11041 ttacgttggt tgtatactaa tgattttgtt ggatcttttt cgatctttga tgcataacga
    11101 tacacatata caatagaaat agctaacaaa ataacgaaca tcaagaatcg aagaccaata
    11161 ccttcaccca tcgaaatccc aacagcttgt gaagctacgc ctgttgcaaa aggatttacc
    11221 gttgaagcta gacagcctac ttgagaccct actaatacga ttgctacagc tactactgta
    11281 tcaaagccta cagccatcat gactgggatc agtaaagcat agaatggaat cgtttcttct
    11341 gccattccgt aagtagagcc gcctaatgca aataacagca tcaatactgg aataagcatt
    11401 ttttcttttc ctttgaattt cttcacaact gaagcaatcc cggcatctag tgcccctgtt
    11461 ttgttgataa tacctaaaaa tccaccaaca accaaaatga agaaagagat tgggattgca
    11521 gcaggtgttt ctttagttag ctcccccgct ggtacaccta gcatcccatt gattggcgcc
    11581 atgaaaatat cccacagccc ttgaggattt tgttgtactc gttcatatga tccagcgacg
    11641 atgttgcctg catcgtctac actatagtgc ccagctggta taaaccaagt aagtacagcg
    11701 attactgcaa taataataaa taagaccgta tacgctgaag gcatttgaaa ttttttcttt
    11761 tttgtttgtt ccatcttctt cttcctttct tttccgttag agacaacaat tttggctcta
    11821 atgttatttt atcaaaaaga gtatcagaac aaaaataata acacgcattt tgtaaaactt
    11881 ttgttcaaaa agttcgtttt tccctattcc ctcctctttt ttcaggtttt taaagctttc
    11941 ttctttttca ttgtagcgtt tccttttttt tataaacaaa cattttcgtc ttttaaaagg
    12001 agaagaattt cacatttgca aagaattgat tgatttttat gcataaatca aaaaaatact
    12061 caaaacaaac aaataaaacg tttacattat tgcatgtctt gtattttttt ccaaaaaaaa
    12121 agaccaagaa atttcttgat ctttttgata tttatttgac tgctgtatga cgttgttcga
    12181 actgatgttg ttttcgactt aaccatggaa gaagttgcgc atgcagcact aaaaagacag
    12241 cactcacgat gaatcctttg atcaagttga aaggaacgat cccaatcagt acatagtttg
    12301 ctaaagacat gcccagcatc tgtgttgcgt tcagccctaa aaacattaag taaagaggcg
    12361 taataacgaa ataatttgcg atactcataa aaatagttag agcgatggtt cctgtaatga
    12421 cacctaaaaa tttgtttctt cctttatgct gtttctttac actaaagaaa taataaatcg
    12481 ggaatgtaaa gatcgttgtt gataagaaac tagcagtgtc tcctaccaaa ttatccggag
    12541 aaaaacctgt agtcagcaga tgtaatactg aacgcaagaa cgctgttgca actccggccg
    12601 ctggaccgaa taagaacatg ctgatcaata ccgagatatc actaaaatcg atcttcaaaa
    12661 aactaaaagc cggcatgatc ggaaaagcaa aatactgtaa aactaatgcg atcgcagcaa
    12721 acatcgctac tgcaaccatt ttctgtacac gggtgttctt catttgaaat cctcctgtta
    12781 ggactcctct tcagcgaact ttttgacgtt tctctccaaa tgaaaaaact ctattttcca
    12841 gggaaaatag agttagagtt atttgatcaa gcgtcgtcaa ataagctcta tcttctttat
    12901 ccagactata ctgtcggtat cggaatttca ccgattcagc tatttttttg caaaataggt
    12961 cgtggactat aaccaccggt cgggaatttc accctgcccc tgaagacgaa ccttatataa
    13021 tttttgttta catattcatt atacatatct attcaaaaaa cgcaacatct aacacttata
    13081 aaaagtaagt gttcattttg agtggttcag caaactgctg acttcttttt tgttcagttc
    13141 acggtaatcc ccaggacgta ggccttgtaa agtcagatct ccgtattttt cacgttttag
    13201 tttttgcaca ggaagaccaa ctgcttgaag catatttttc acttgatgat tacgtccttc
    13261 gtggatcgtc aattccacga tactgtggtt tgtcttagga tccactgata aaatttggaa
    13321 tttagctgga gatgtttttc gtccttcgat ctttattcct tttgtcaaag gtgcaagcat
    13381 cgattttgta gcgatccctt ttacctttgc aacgtaaact ttatccactt catgttttgg
    13441 atgtgtcagg cgctgagcaa aatctccatc atttgtcagt agcaagatcc ccgaagtatc
    13501 gtaatccagt cgacctacag gatagatacg ttcttttacc atcggcaaaa gatccgtaac
    13561 aacttttctt cctttgtcat ctgcaacagc agaaataact cctttaggtt tgtacaataa
    13621 atagtaaccg tattcttctt gataaattgg gacttcatcc acttccacag tgtcatgttt
    13681 cccaactttt atccctaatt cccttacaac ttgtccgttt acttttacac gtcctgcaag
    13741 gatgaattct tctgcttttc gacgagaagt gatgccagcg tgggcaatta ctttctgcaa
    13801 tctctccatt acaattattc tcctttattc attccatcaa agaatagatc tggtgacacg
    13861 tcttcttcaa gtgaaatttc catttcttgt gtatcaggca gttcttctaa tgatttcaaa
    13921 ccaaaataat ctaagaagta gccagttgtt ccatataata tcggccgacc tggtccttct
    13981 actctacctt tttcttcaat cagtttatgg gcagctagac gctgtaccgc tcctgaaacc
    14041 tgaactcctc gaatctgctc gatttcagct cttgtgattg gctgtttata agcgatgatt
    14101 gctaaggttt cgacggcggc ttgagataat gtgtttgatg tcccttgcgc atatcgctta
    14161 agtaagggag ccagctcttt tttagtcgtt aatacataat ggctttccgt ttcaaaaata
    14221 tgcaaagctg agtgcgagtt ttgagtgtaa gattctttta attctttcac taaacttgtg
    14281 acttctgctt cgctgagatt taacagtccg cttaattctt cattactgat cccttcctcg
    14341 ccaacaataa aaagaagggc ttcaagttca cttaatttcg tcatgttcgg tatctcctac
    14401 tgctggataa agcataattg attcatagtt ttctttttgt tgcgcaatga tctgcccttt
    14461 tttcatcaat tctagcaaag ccataaaagt agtgacaact tcacttttag aaggtgactc
    14521 aaaaaaagaa tcgaaagtac agccatgcgc atttcttttt atacgctctt cgataaatac
    14581 cattcgttct tcgatcgttg tgtcatcggg cgtgatcgtt ttttccactt tttgagaaaa
    14641 tttcttacgt tctaagattt tctgcatggc acggatcaaa tcgatttttt tgacttgtcc
    14701 tcgcttcaac ggcttttcag catccgctaa cccatcgatg ttcataggtt cttttgtgta
    14761 ataaagactt cgttcctctg ctttttctgt cagtctttca gctgcatatt tatatttacg
    14821 gtattctaaa agctgagtga ccaattcttc tcgaggatct tcttcccata attcttcatc
    14881 gtctgtgccg aattcttgga caggaagcaa tgtcttgctt ttgattgcca tcaatgtagc
    14941 agccatcact aagtattctc ctgcaacagc tagctcgagt gttttcattg tatggatata
    15001 attcatatat tgctccgtga tcgtagcgat cggtatatca tatatatcga tttccatttg
    15061 ctgaatcaga tgaagcagca gatcgagagg accctcgaat acatctaatt taatattgat
    15121 ctccgtcaac tcattcactc tttcttcttt ttctttgcta gccattttcc aatgtaaggc
    15181 tctgtgattt cagttgcacg gatggagaca tccgggtact tttcctgtaa ttcatctaac
    15241 atttgaaagc ccatattctc accgcgataa gacggattca aagaaatgtc atggatgatc
    15301 agctgatcgt tcgttgccca gtaaatacca ataatccctt gaatgttggt tgaaccttct
    15361 ggcgtaaaga aaaaaagttc ataatcgtct tcagattcgt acgtatcaat ctccttcaac
    15421 aaagaagttt tacctgtcag tttcttatgg aaactcaata gtcccatagc aattttacgg
    15481 ttttctttcc ggtaatgtgt taacatcttc tcaccttcct atgactaagc ccttggaaaa
    15541 tgctgcttat aaacatccgt cattcttttc ttcgtgatat gtgtataaat ctgagtcgta
    15601 gagatatccg cgtgacctaa caattcctgt actgtccgca aatcagctcc attttctagc
    15661 agatgtgtgg caaagctatg ccgcagcgta tgtggtgtta cttctttgta aatcccagcc
    15721 tctcgtacta actgcttcag atttttccag attccttgcc gagaaagacc tttcccatga
    15781 ttattgacaa atacatgcat ttcagatgcg tcctttacaa gtaatggacg tgcttcgtct
    15841 aagtagcgtt ccagccattg gatcgcataa tcacctaaag gaatgatccg ctctttatct
    15901 ccttttccaa ctgtctgtac cagtccaaga gaaagatgaa gatctcccaa tttcaatcca
    15961 atcaattcac tgacgcgcat cccagtagca tacatgactt ccaagattgc acgatctctt
    16021 atccctaacg tttttgtcgt atcaggtgct tcaatcagct tttctacttc tgtcagagtc
    16081 aatgtacttg gtaatttctg tgctttcttc ggcgtatcga tatgttgcat cggatcatga
    16141 tcagtgatac gctcttgccg taaaaactga tggaatcttc tgagacttga gatcatccga
    16201 gtaacagttg ctgtcgcttt tttttcttca tgcaacttct ccagaaaacg gatgactaaa
    16261 aagcgatcga catcctgcca tgaagcaatt ttctgctcct gtagaaaatg caagtactgt
    16321 tccaaatcac gttcatagct ttgtcgtgta ttggcggaca atccccgttc aatattcaag
    16381 tagtggagat aatcgttgat ttgctctttc ataataatcc ccctcatgcc tctctatcat
    16441 atcagatacc gcttcattct gatagtcttt ttccataatc tgagcaaaga aaaagccgtc
    16501 tagacactca gacggactgg tttctttt
//
LOCUS       DAFEEZ010000064        16494 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000064
VERSION     DAFEEZ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.067"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..525
                     /gene="scm"
                     /locus_tag="LP245_002233"
     CDS             <1..525
                     /gene="scm"
                     /locus_tag="LP245_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBL1520127.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
     gene            complement(680..1666)
                     /locus_tag="LP245_002234"
     CDS             complement(680..1666)
                     /locus_tag="LP245_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBL1520128.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1689..2255)
                     /locus_tag="LP245_002235"
     CDS             complement(1689..2255)
                     /locus_tag="LP245_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBL1520129.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2269..2685)
                     /locus_tag="LP245_002236"
     CDS             complement(2269..2685)
                     /locus_tag="LP245_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBL1520130.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3142..5076)
                     /locus_tag="LP245_002237"
     CDS             complement(3142..5076)
                     /locus_tag="LP245_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1520131.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5357..6313
                     /locus_tag="LP245_002238"
     CDS             5357..6313
                     /locus_tag="LP245_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBL1520132.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6403..7506
                     /locus_tag="LP245_002239"
     CDS             6403..7506
                     /locus_tag="LP245_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBL1520133.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7519..8472
                     /gene="menA"
                     /locus_tag="LP245_002240"
     CDS             7519..8472
                     /gene="menA"
                     /locus_tag="LP245_002240"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBL1520134.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9286..10632)
                     /gene="gor"
                     /locus_tag="LP245_002241"
     CDS             complement(9286..10632)
                     /gene="gor"
                     /locus_tag="LP245_002241"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBL1520135.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10766..12019)
                     /locus_tag="LP245_002242"
     CDS             complement(10766..12019)
                     /locus_tag="LP245_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBL1520136.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(12025..12948)
                     /locus_tag="LP245_002243"
     CDS             complement(12025..12948)
                     /locus_tag="LP245_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBL1520137.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13169..15661)
                     /locus_tag="LP245_002244"
     CDS             complement(13169..15661)
                     /locus_tag="LP245_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBL1520138.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15668..16135)
                     /locus_tag="LP245_002245"
     CDS             complement(15668..16135)
                     /locus_tag="LP245_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBL1520139.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16271..16344)
                     /locus_tag="LP245_002246"
     tRNA            complement(16271..16344)
                     /locus_tag="LP245_002246"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16308..16310),aa:Arg,seq:acg)
     gene            complement(16402..16475)
                     /locus_tag="LP245_002247"
     tRNA            complement(16402..16475)
                     /locus_tag="LP245_002247"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16439..16441),aa:Pro,seq:tgg)
BASE COUNT         4869 a         3458 c         2934 g         5233 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
      121 gcttcaagtg acagtacaga tactacctct accacaagtg atagctcaga ttcatctacc
      181 actacaagtg atagcacgga cacgtcagct tcaagtgaca gtacagatac atcctctacc
      241 acaagtgata gctcagattc atcaacttca agcgatagta cagacacgtc gtctaccaca
      301 agcgatacac gtcatgcaag tgtctccttc tcaaaaacaa gttcggataa caggacgaac
      361 tttaacttaa ctaataaaac aagcaatgac aatggaaaca aatcaaaaag agcacttcct
      421 aaaactggaa gtcaatcgaa taattggata acactcgcag gcgttatatt acttgtaatc
      481 ggtttaagaa tcacttttat gagttataag aaatcgaaaa ggtaaaaaaa tattcaagat
      541 aaaaaagagc aacgtcgcta acggacgttg ctctttattt ttgcttttta tcataaatac
      601 aagaactaca attcaatttg tcaaaaaaca cgtagatttc cttctgagaa atttatttac
      661 gtatcgaacc tttccctatt cagtctttgc gatccaaaat cagttgggta agggaaaaga
      721 gattctcttt tgttcgaaga gaggtggcag gtaatttctt tatttccttc aaagcctttt
      781 ctgtgtaaga ggccgctaac ttcctagctt cttccacgcc tcctgtatgt tcaacgattt
      841 tgcgtacggc gtcgacatct tcttctgtca ttgccgcttt cttctctaaa taaggtagta
      901 gctttggttt gtttttttgc aaagagtaga tcaacggtaa agaatagacc ccttgacgca
      961 tgtcttctag tacaggtttg ccgatttcct ggctctcttt tgtataatct aaaatatcat
     1021 cgataatctg aaaggccatc ccgatagaaa gtccgatatc tcctgctttt tttgcgaagc
     1081 gctcgcttgt tccactttca aaagcgccaa cagaacaact taattggaac agttcagctg
     1141 tcttacctga aatattttcc aaatattctt ttacagaaag ttcataatta tagcgatcat
     1201 ccatctgccc taattcgcca ttcaatactt tttccatact gcgagaattc aattggagac
     1261 ttttcaagga agtggagtaa tcagacaata gtttaaaaca gcagacaaat aaatagtctc
     1321 ctgcatagac agaaacgaca ttaccaaact gactacggat attaggctga ccacgtcgca
     1381 gatccgcttc atcaacgata tcatcatgga tcagtgtggc cgtatggagc atttcgatag
     1441 aagctgccaa agcgatggct ttgtctcgat cttgctctgg tccaaattgt gagaacaata
     1501 gctgataggc aggacgcaac agctttccgc cggcatggat cgtttctttg atggcttgtt
     1561 cgacaggttt gtttttcagg cggacagttt cttccatccg ttttagtgtt tctgtcaatt
     1621 ctttacttaa agcaggatag ttttcccaca ttggatgtag cttcataaaa aaactccttg
     1681 tgtgacgatt attttttggt aaacattggg ctccattttt gtttggttcc ctgctcataa
     1741 tctttttgga atcgttgaag tgtctgcaca tgtcgtaaaa gataattcgc tgcgatcccg
     1801 attgcaatcc ctgataaaat ccctaaaact gaaaggactg gcaagtacaa catgactgtc
     1861 catgattgtg caatgaaaga agccatcaaa agctgtccga cattatgcat gaaaccgccg
     1921 gccgcactaa ttccgatgat actgacacgt tttggtccta attgcttgac caataacatt
     1981 ccaaaataac taagcaaagc accactcata ctataaagga atgtggaaat cgttccgcct
     2041 agcaaagtag tcaggaatag tcgtagccaa agtagtaaga agctgtcttg ttttttcatg
     2101 gtaaaaatgg caacgatcgt gattagattg gctaagccta gttttgcacc aggcgcaaaa
     2161 gaaaaaggat aagggatcat attttccaat aaaccaatga tcactccttg tgcaacaagt
     2221 agcgaaatat aaatcatttt ttgtaattta ctcatggtgt gtgaaggtct aataaatcag
     2281 actgtcttcg tcacctccat ctgttgaacg gacttcgatc actaatttat gtggcaaaca
     2341 gacgatggtt tcgccatttt tcgttgccca gcctcgacgt acgcagatct ggtcatcgca
     2401 atctgcttct tttatccgta ctcgatcgcc atctatctcg atcaagttat aatctccgtg
     2461 ttcatctttg taagtatatg tgttgctctc ttctccagcc atcaaaggga atgttttgat
     2521 ttctgtgcca tccacacgca gtaccgcttc tttttctgct gttgcggtgt tttgctgaag
     2581 accaaaaatc atgactggta aaaaagaaag aacagtcaaa agcaaaataa taaaaacatc
     2641 ccaaggtttg agcagacttt tttcagcaaa ttctttaagg ctcatttttg ttctcctttt
     2701 tccagattaa ctcacccaat tttagcataa aaacaagagg ttgtgacacc tgtgtcttgc
     2761 tttgagtaat aagaacgaag aatagaaaac agctttccat gttttctaat tctttgggct
     2821 tattaccgag aagcagcagg tggaacaccg tttataacaa gaggttgtga cagaagtggg
     2881 caacttcaag aaataagaag gaatttacga aaattacttt tcaagttttt gtgaaatttc
     2941 ggcttatttt tcgaagaagc tacttctgga acaccgttta taacaagagg ttgtaacaga
     3001 ggttgtgaca cctgtgtctt gctcatggag gcttatctcg ggcatcttat tcctttaatt
     3061 ttacataaaa aggaggctgt gacggtttgt ctcagcccct ttctattgaa atcttgcatt
     3121 caaataacgt tctttatcta tttatttctt gccgtactgg gaacttggtc taccgtacca
     3181 ccaattacct agtgtacgtt gtagccatgg aattacccag cgatccaacc caatcgcacg
     3241 tccggaaccg ttcatcaatg cgaaagcaac aaaaatgaac caaatgttta cccagtaaaa
     3301 catgcctgat aagcagaacg tgatcaccaa tacaatcgtt gtcgcactgc atagccatgt
     3361 gaataatcca gcaatcaatg ctaatgccaa ggcaatttca aagaatacca tgaatttttg
     3421 gaagaacatt gctacatcat tgtttggcat gatcacttgc atgatctttg tgaaccagtc
     3481 tggtgacttc tcaatcacag ccattggttc ttcaccgtat gcataactca aaccaaaatg
     3541 tgcagcttga gtcgctgctt ctccggcact tgcccctgct ccgctggcag ctgtggttgc
     3601 atcaccagca gcagaagcac cactggcaac atctgttaca ttgtattccc atgtccaagg
     3661 gaacacactg tttccagtga accatgatcc ttcaccaaac caagtacttg gtttgaacac
     3721 ttcaccattc ccaatgattt ttttggaagc ttcaacgaac caaactaaac catagaaaat
     3781 acgaagtggc acactccata agacattgcc gtaacgagaa gaatgtcctc gagtcacgtt
     3841 gcgatcatct ttgatatgga aaaactcatg cattaaatat tggaacatat aataaccaga
     3901 acgaatatca aagaagtatt tcaaattcac gatatgtttc attacgatag ctaaaaatcc
     3961 gcttaaatgg atcttatcaa ataggttagc taccccccat ttggcaccaa tagaaaccat
     4021 aaatccttga tagtttcctt taaatttatg cttttctccg cctttgatcg aagccacgat
     4081 attcgctgcg gctgtgtgtc ctgtttgttc agcagcttga acgatctgcg gtgtcggtgt
     4141 tcctgggaat tcttcataaa agactaaatc accaatgata tagatgtttt tatcttcgta
     4201 gccttttgcc tgcatatatt cattggcgat caaccgctgt ccgcgtgctg attctaatcc
     4261 aaagtcagca gcgtcagaag ttcctttgac accagctgtc caaatcagtg tgtgagtcgg
     4321 aatgttgcgt ccgtctttca atttgatatg atcagcagcc acttctacga ttggtgcatt
     4381 caataataat tccacgttgt gcttacgcaa atagcgttca gcttttgcag catcatttcg
     4441 atccaacata ttcaagatcg tcggcattgc ctctacgacc atcagtgtga tttcgtttgg
     4501 atctaattta taatctttgg ctaggcgatt tttccagtcg atcagttccc caatcatttc
     4561 aataccggta aatccagaac cacagacaac gaaagtcagc atggctttac gcagttcatc
     4621 atctggttcc aatgcagctt ttgctactgt cttctcaata tgttcccgaa tccttacaga
     4681 atcttcaaat gaccaaaggg tgaatccgtg tgctttgaca ccaggtgtac caaagtcatt
     4741 cggctctccg cccattccaa ggatcagctg atcaaaagga taggaaccta atttggtctt
     4801 gacgattttt cgttctttat cgataccgat tacagtgtct gtgacaagtt gtacattctt
     4861 ttgacgagca aacaaatgct gcagatcgta ttggattgct tctggttcta cacgtccgcc
     4921 agctacttca tgcaactcgg tcatcatagt atggtacgaa tgacgatcga tcagagtaat
     4981 tgctacatct tcttttttca gtttctttgc caagtatttt gtagctgaaa caccggcata
     5041 tcctgctcct acaacgacaa tattttgctt tgccattgat catccgctcc ttatagacta
     5101 tctatataat gaatatatga taattctttt agtttgatac ttattacaca atctccatat
     5161 attatataga tgttctgttc ttttgtctaa ctccttttgg atttttttca aattttaaaa
     5221 taaagcgttt tttcacgaaa tttgctgaaa gaaaacgttt gaaatattac atgggttatt
     5281 tatcaaaaat agttgactta taggctaaaa agattagaat gtataatgaa tcacaaagaa
     5341 aaattgtgga ctagaaatgg aatggtgggg tattaaaatg aagaaaaaac gttttgtaac
     5401 tggatttgcc gtattagcat tttcagctct agtgttaggc gcttgcggcg cagatgacaa
     5461 cggaagctca aactcttctt ctgaatcatc tacagcacaa tcttcgactg caaaaagcac
     5521 aacagaatca tctgcaaaag ttgtagctgg cggagatttg caagacggca catataaatt
     5581 agaagaaaaa aattattcaa atggttaccg tgcagtcttt gaaatggttg taaaagacgg
     5641 caaaatcact gaatcaaaat atgataacgt caatgaaaac ggcgaatcaa aaacaaaaga
     5701 tgcagaatac aacaaaaaca tggaagcaaa atctggcaca aacccagaaa aatacattcc
     5761 tgagttgaat gaccaattct taaaagcaca aagcgcaagc ggtgtggaag tcgtaactgg
     5821 agctactcac tcatctgaaa gcttccaaaa ctacgcacaa caattgatcc aagctgctca
     5881 agctggtaac acagatacaa tcgaaatcga caatggtgct gatttgaaag acggcactta
     5941 caagcttgaa gaaaagaact actctaacgg ctaccgtgtg caattcgaaa tgacagttgc
     6001 tggcggcaaa gtaactgaat caaactttga ttatatcgac aaagacggta aatcaaaaca
     6061 agatgataca gaatataatg aaaatatgaa agcaaaaagc ggtacagaac caaaaactta
     6121 catccctact ctgaacgacg aattcgtcaa agcaatgggc gaagaagatg gctcacctgc
     6181 taatgtagaa gttgttacag gtgctacaca cagctcacat tcattcatca tgtacgcaca
     6241 acaattagtg aatgcagctg aaaaaggcga cactcaaaca atcgaagtag ataatatcgt
     6301 aacagaaaaa taatcacata atcatactaa taaaagttgg agggtgggac gatagccaga
     6361 ttaggcagtc gtctcacctt tcaaaatgaa gagaggaaaa agatgcggaa aaaactacta
     6421 ttttccttaa tcacactggg catctctttt atggtgctaa ctggctgcag caactcagca
     6481 aataaaacaa ccactgaaag ttcagcagct accaagatat tgaaagatcc atattctgat
     6541 gaacagttct tgttagggac ttacgttcgt atccgtgtgt atgatgaagg caaagaatca
     6601 gcattgaaac ctgccttcga tcgagtaaaa gaacttggtg ataaaatcac gatcaatcaa
     6661 aaaggttctg agatcgatga agtgaatgag caagctggga tcaaaccagt aaaagtttct
     6721 gatgacgtct acacgttagt caagcgggcc tacgaatata gccaagattc tcaaggcgga
     6781 ttcgatatgg cgattggtgc aatcacacaa ttatggcgaa tcggttttga tgacgccaga
     6841 aaaccttccc aagaagaaat cgatcaggca ttgaaattag tggattatca taagatcgaa
     6901 ctaaatgaca aagaaaaaac tgtttatcta aaagaaaaag gaatgatcat cgatttaggt
     6961 gcaatcgcca aaggttacat tacggacgaa gtagtgaaag tcttgaaaaa acaaggagtg
     7021 accactgcca tcgttgactt gggcggtaat gtctatgtct taggccacag cccaagaggc
     7081 gaaaaccaag actggacagt cggcatccaa gatccgaaca tggctcgcgg atctgtttta
     7141 ggttctatta aagaacggaa caaaacatta gttacctctg gaatttacga gcgttattta
     7201 gaagtagatg gcaaaaaata ccatcatttg tttgatccaa aaacgggtta tccgttcgac
     7261 aatgatatcg caagtgtcac gatcataaca gataaatcaa ttgatggtga cgggttgtct
     7321 acagcagtct tttcaatggg tgtgaaaaaa ggactggaat acgtcgaaag cgaattgaat
     7381 aacgggacgg aagcgatctt cgtgacaaaa gacgataaag tatatgtgac cgatccaatc
     7441 aaagacacct tcaaattatc ggaggactcc cattacacga tgggtgaccg ttctgaacta
     7501 aaataaggag tacgaaccat gacactaaaa atctttttag aagtagttga aatacgaaca
     7561 aaggtggcta gtgtatttcc ttttgcggta ggggtattat tctctatcgc tttttttcat
     7621 gagatacatt ggctaaacac ttttttattt tttattggaa tgctagtttt tgatttagcg
     7681 actaccgcta tcaataatta catggattat gaaaaggctc attctgaagt atataagtat
     7741 gaagaaaatg tcattggccg cagaaatcta tctcctgtat tgattcgaaa catgatttta
     7801 gctatgattg catttgtttt tgttatcggc gttattctaa cgatcaatac gggttggctt
     7861 ttacttttga tgggatttat ctgttgtttt attggagtat tctatacatt cggaccgatt
     7921 cctttatctc gaatgccttt aggggaaatt ttcagtgggg tgactatggg ccttggaatt
     7981 tttgccatgg tcgtttatgt caatacattc ggttcagatg tctatgatct gacagtcaac
     8041 ttttcatctg gacaatttga tttggtagga aatctttggg ctatagcagc aatcgtatta
     8101 gcttccttac ccttggtgtt tacgattgcc aatatcatgt tggctaataa tttgcgggat
     8161 cttgaccgtg atattgaaaa tcatcgctat acactagttt tttatatcgg acgtcctgcg
     8221 ggaacagtct tattccagct attgatgtat gcttgctatt tcgtgatttt aatggggttg
     8281 ttgagcggta tctatgaatg gccgatcttg gtcaccttct tgaccttgcc aattgtgaag
     8341 aagcatttgg atcaattcaa gcaaacgtta ccccagccta tcagtttcag ctattccatc
     8401 aaaaatatgg tcttattcaa tgccagttat gtattggggc tattactaac aatcattatg
     8461 caagccattt aacagcatga agaggttgtg aaaaaactgc cctgcatcaa gtaataagaa
     8521 cagccaaata aaaatagctc cttatatttt tcgtttggtt gggcttatta ccgcagatgc
     8581 aagcttttga acaccgttta tcaggaggtt gtgaaaaagt cgcttagttt cgagtattaa
     8641 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
     8701 actggctttt gaacaccgtt tatcagaggt tgtaaaatca gtgttttgtc ctgagtatta
     8761 gagaaacaaa tggaaaaata gttcctcata ttttgccgtt ttttgagcta ataccgaagg
     8821 acagctgatt gaacactatt tgttcggaaa aagtgactaa ctatgacaca atttttttca
     8881 cagtcccttt tttcacttga tttgattcgt accagcgaac ttgacgagaa ctttcttggt
     8941 ttggtaacta tatggtattc ttttaacatc ctcgtttgct tcttctaatt tatttataca
     9001 aagtcacact tttttaaaca tctgttcttc gatacatttc tatttctttt aaacatcgat
     9061 accaatattt tgaacttaag agtgcatacc aaatggattc atttactctt cgtcagttac
     9121 gaagataatc aaaatctcca acttccctac ttatttcgtt ttgagaatta tcgaagcaat
     9181 cttacataaa taactaaaaa acaaaaaacc agaaaatcag tatactgatt ttctggtttt
     9241 acatggtttg ttcaataaaa agctgttgga actgttaata ttaaattatc gcatcgttac
     9301 gaattcttcc gctcctgttg gatggatggc tactgtattg tcaaagtctt ctttagttgc
     9361 acccatcttg atagccacgg caaaaccttg cagcatctca tcgacaccaa caccaatagc
     9421 atgtaagccg acgattcttt cttcttttcc gacacagatc aatttcattt cgcatttttg
     9481 gcgataatca tttaatgcaa agtacattgg ggtaaagcgt gaacgataaa ctttcaattc
     9541 attttcgcca tatttttcca atgcttcttc ttctgtcaaa ccaattgttg caattggtgg
     9601 atgcgtaaag acgactgtcg gaacaagttt atagtcaaga taagaatctt tctttccatt
     9661 aaataaacgt tctgataaac gtctaccagc tgcgattgca acaggagtca gatctaattt
     9721 accgatcaca tcaccaacag caaaaatatg ttcatccgtt gtattttggt atttatctac
     9781 tttgataaac ccttttttgt ccaattccac atttgtattt tccagaccta atttttcggt
     9841 attcggtaca cgtccaccgg caaaaagtac acaatcacca gttaaggttt caccattttc
     9901 aaatagcacc gtatattcgt cattgttttt agtaatttct ttagcaatat gatgtgcgta
     9961 agtttttatt ccagcttctt ggtacatttg gatcaaattg tccgaaagca ttttatcaaa
    10021 cgttctaagt ggtcgttctt ttcgatatgc ccacatgact tcactaccta aaccacgaaa
    10081 tacacctgaa agttcagccg caatgtatcc agcacctaaa acgattgctc tcttaggtaa
    10141 ctctgttaat tcaaaaaatc catttgaatc aattgcgtat tctccaccag gaatggtcat
    10201 tttacttgca cggcctccag tagcgatcaa gattttagga gcacgatagg tttcaccgtt
    10261 tacttcgatc gtttgactat cgataaaagt agcgtaacct tttatagcct cgacatgatt
    10321 gctatctaat cctctttgat aagcaccgtg tagaaaatca atatattttt ctcgtctttc
    10381 tactagaccg gcgaaatcaa cattttttaa atctgcttgg ataccgtaac ttgaggcatc
    10441 tcgttcaatt gtttccaaaa tcgtacttgc ttgccacata acttttttag gtacacaacc
    10501 gacgttgaca catgttccgc ccaattcatt cgcttcaatc agcaaaactt ttgcgccatg
    10561 catccctgct ctgtttgctg aagcaatacc gccagagccg ccaccaatta cgatgtaatc
    10621 atatatttgc attttgttcc tccttattga agagatcaat caaaaccttt atttaacgat
    10681 cctttttcta cagaaaacaa gtgtaacact tttcttgaat tttgtatgcg aagatgctta
    10741 aaacagggat atatcagctt tttccttatt tacgttttcg gatcatatct ccaggtttca
    10801 ccggctgtgc gactggcata gttaaaatca tcattggatt tggtgctcgg tcaatggatt
    10861 cgccttcttc attatgcata acttcaacgg tttgactgaa atgactgaat cctggaccat
    10921 aaaattcgat ttcatctcct acagaaaaca agtttctctg acgtatcgta gcaatctgtg
    10981 ttgcctcatc ataagataat acttcaccga caaatttata tactgggatt ttacgacgtt
    11041 caccgaataa ttgttcgttt tcagttggtg tattgtagta aaaacctgta gctaattctc
    11101 gttgtgctac tttccataac tcgtcgatcc attcttgctt gcagacatag ttttcaggat
    11161 cttccatata actgtctaca gccgctttat agacatttga caccgtagat acataatgga
    11221 tcgatttcat tcttccttcg atcttgaagc tgtctacgcc gttttcaatc aattctggaa
    11281 tatgttcgat cattgacata tccactgcac tcatcgagaa ttcttcttcc acttcgcctg
    11341 tatcagttaa actgtttcgt tcttgaccaa aaggcatatc gaacaatcca tacttccagc
    11401 gacaagattg agaacatccg ccacggtttg catcccgcat cgacatatgg ttggacaatg
    11461 tgcatcgacc agaataagag atacacatgg caccatggat aaatgcttcg atttcggtat
    11521 ccgtattttt acgaatctct gccacttcct ccattgaaac ttcacgagct aaaacgacac
    11581 gttccaaccc ttcttctttc cagaattcca atgtctcaaa attagttgct gaagcttgag
    11641 tggataaatg gatcggcaga cctggggctt ctgtcgcaca aatttcgatc aaagctggat
    11701 cagaaacaat cactgcagaa ataccgacat cacgcaaact gcggaaaaat tcccctgctc
    11761 catcttcatt tccttcatgg gtgaccatat tagcagcaac gtataccttc gcatcatgtt
    11821 cttttgcaaa agcaactcct tcagccattt cttcataagt aaaattacct gcacggcttc
    11881 ttaaaccata tgcattcccg ccaatatata ctgcatctgc tccataatgg atcgcggttt
    11941 ttaacttttc cagtgttcct gctggcgcta ggatttctgg tcgtttcaat tttcttttta
    12001 ctgtcatttc tttcatcata ctccttattt gatagcagaa ggatcaatat aaaagaatcc
    12061 tgtatctaat tcacggtttt caggatgcaa tttactgatt tcgctagtca ttttttccgc
    12121 tttttcttga tcccagctac cttctaaaat ttgttttttt gcttcggcga atagtcgagt
    12181 gatgtttacg aatttttcgc ctggagtaaa taatccgtcc aatttccatg tacagtaatg
    12241 atgctgataa agttcattca attcattcga gagattcaga tcattgctgg caaaaatatg
    12301 tgtgccatga ctatcttcat aaatagaata atgtgtctct tcttttttag gttccgagat
    12361 aaaaagacct ctttcacgat ctttttgttc gtcttgtttc gtatagttat agtaattctg
    12421 tagcagtgga cgtttggatt gatggatgca tgtagcacca tacacaaggg tttctacagg
    12481 aatatcgagt ttttcttcca tcgccttcat ctcttcaaaa ggaacttcac gagcaagtac
    12541 tgctccaact gcgccttttt tcgcccagaa attgatttga cgtgcgctcg ttactaatgt
    12601 ttcagcatca taaatatacg gtatacgcaa ttcaggattt tttttcatcg tataaataat
    12661 acctgtatca ccaactgtga tcacatctac gtttatttct tttaaaaaag ccaaatattc
    12721 aggtacattt ttcatttttt caggatgaat gatcccattt acagcaatat tcgctttttt
    12781 accatacttg tgtgctaatt ctaccaattg tcgctgttct tctcgtgtaa atgaagcagg
    12841 cagacgcaat ccaaattgct cttcaccgaa atatagtgta tctgcacctg cagcaagcaa
    12901 ctgttctgct tgttcaatag tttctactgt ggttatgagt tcgatcataa ttttctcctc
    12961 ctacaacttc ataatagtag catagctcta aaaactttcc aatacttctt ctatttaaag
    13021 tcggattttt gaaaattatt tcacaaaaaa tcaaaataaa gttcgatata ttctgtccaa
    13081 atataaaaag agattgtgac aaaaatcttg tcacaacctc ttaatcaagt cttactatta
    13141 taaaaattca gctacacagg ccaagtaact atagggaacc tactgtttcc tttttaggtc
    13201 cgcgaacatt caatgtgatc ttaccttttg aagcacctac tgttacgtgg tcacctaaac
    13261 gaatttctcc gccaagcaaa gcctcgctca atcgatcttc aatttctttt tgaagtgcgc
    13321 gacggattgg acgtgcacca tattcaggat caaatccagc tttcccgatc acatcgattg
    13381 cagatggtgt gattttcact tgaatatctt gttctttcaa tcgtttgata atcgctttgc
    13441 tcatgatttg gacgattgta tggatttcat ctttactcaa tgaatggaag acgacagtct
    13501 catcgattcg attcaagaat tcaggtcgga aagctttctt taactcttct aagatacgtt
    13561 tttgcatggc tttgtgatct ttagtaacat cttggacatt gaatccgaca tttttttctt
    13621 ctcgaatttg tgtcgctccg atatttgaag tcataatcat gattgtattt ctaaagtcca
    13681 cttttctacc tttagaatct gttaaatgac catcatccaa tacttgcaga agtaaattga
    13741 aaacgtctgg atgtgctttc tccacttcat ctaagagaat cactgaatat ggtttttgac
    13801 gaattttttc tgtcaactgt ccaccttcat cataccctac gtatcctgga ggagacccga
    13861 ttaatcggct tgtactgtat ttttccataa attctgacat atcaacacgg atcagggcat
    13921 cttcacttcc aaacatgact tctgaaagtg ctttggccaa ttctgttttt ccgacaccag
    13981 ttggtccaag gaacatgaat gaaccaattg gacgatcagg atctttcaat ccgcttcgtg
    14041 cacggcggat cgcacgtgaa actgctttga cagcctcatc ttgaccaacg acacgttcat
    14101 gcagaagtcc ttccagttct aacaagcgtt cgctttcttt tttctccaac tgctgtagag
    14161 ggacaccagt ccactccgat acaactgtag caacatcttc ttctgttaca cgatcagaat
    14221 aaccttgctc ctgttttgct tcaattgcag aaactttttg cagcttttta cgtagtgctt
    14281 tttcttgtct gcgtaattga gcagcatttt caaagtcttg tttttggatc gctgcttcct
    14341 tttcttgtac tagttcatcg atttctagtt tgatcacagt tgattttgtt aagtgatcgg
    14401 tttgatccaa acggactttc gctgctgatt catcgatcaa atcaattgct ttatcgggta
    14461 gttgacgaga agtgatataa cgaacagaaa gattgactgc tgctcgtaca gcttcatctg
    14521 tgatctccac tccatggtgc tcttcatatc ttgtacgtaa tccttgaaga atcacttctg
    14581 cttcttcagg agttggctca tctacttgaa tgcgagcaaa acgtcgctct aatgcagaat
    14641 ctttttcgat atatttttga tattcatcta gggtcgttgc tccgatcgtt tgtaattctc
    14701 ctcgagctaa cgccggtttc aagatattcg aagcatcaat tgctccttct gctccacctg
    14761 caccaattaa ggtatgcaat tcatcaatga ataagattac ttgaccatca ttatagattt
    14821 cgtcgatgac ctttttcatt cgatcttcaa attcaccgcg atatttcgta ccagcaacca
    14881 aagatcccat atcaagcatc atcaggcgct tttcttgcat gtcttctggc acttcaccta
    14941 aaatgatttt ttgagctaac ccttcagcaa tggctgtttt gcctacacca ggttcaccca
    15001 ccagtacagg gttattcttt gtccgtcggc taagaatctg gataagccgt ttcacttctc
    15061 tcgaacgacc aacaactggg tccagcttgt tttcttttgc taatttcgtc aaatcacgtg
    15121 ctaatgaatc tagcgtaggt gttccttgcg gtgtttgccg tttatcttgt acatttacat
    15181 ttctacgacg attcattcct tttccagcag aatcaccagc tagccccatt ttttgtttca
    15241 gaacttgacg ggcttttgaa aggctgatac ctaagttgat catgattcga gtagccatga
    15301 tactttcatc ttttaataag ctcatcaaaa tatgttctgt tccaactttt tgagaaccag
    15361 ttttcttcac ttcgctgcta gctaaagcaa aaacttgttt cattcttggt gaatatggaa
    15421 gaaagactcc tttagggtaa gaacggatac caccataacc aatcagatgt tcaatttctt
    15481 cataaatttc cgtttcattc aaatccattt cacgtaatac ttttccagca attccatttt
    15541 gctcgaccac taaggctagt aaaacatgtt ctgaactaac tgattgatgt ttcaaccgtt
    15601 ttgcttcttc ttgtgcaatt tctaatactg cttgggctct ttcagtaaaa agttcttcca
    15661 tctaatctca cttcccatct tcataactta aacgttccag aaatgctcgg agaatccgag
    15721 cacgtgtatg atcttcatat tcattgaaat tcaatgtgtt ttttgcaatt gcactcaaca
    15781 tcaagtttcc ttcttttttt gtaattattt ggtcttcata aagtttttga ataatagcaa
    15841 aagcattttt ctcactgatt gtatcatcaa ataactgatt tatctgctca agtaattgtt
    15901 ttttatctga aatccttact tttgcaattc gtatataacc accaccacca cgtttgcttt
    15961 ctactagata accacgttgg atggtaaaac gggtattaat cacatagttg atttgtgaag
    16021 gaacacagtt aaagaggtct gccatttcaa tccttcgaat ctcgatcatt tcactatttt
    16081 ccagaatttt ctttatatat gattcaatta aatccgaggt attctgatgt gccatcttat
    16141 tcattccctt tgactaatat tgaccttaat tataacgaat ttgataatag aaagaaagaa
    16201 gaacgctttt tgttaaataa atcctttaga atcaacaaaa aaaaatacgg aatatactat
    16261 tccgtatcga cgcgcccaag aggagtcgaa cccctaacct tttgatccgt agtcaaacac
    16321 tctatccagt tgagctatgg gcgcatattc aatttaaaaa aattataaat catttgaaaa
    16381 caaaaagcaa gataaaaaaa atcgggaaga caggattcga acctgcgacc ccttggtccc
    16441 aaaccaagtg ctctaccaag ctgagctact tcccgtttaa aaaataaaaa agac
//
LOCUS       DAFEEZ010000065        15980 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000065
VERSION     DAFEEZ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.068"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..2196)
                     /locus_tag="LP245_002248"
     CDS             complement(<1..2196)
                     /locus_tag="LP245_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBL1520140.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRN"
     gene            complement(2502..3449)
                     /locus_tag="LP245_002249"
     CDS             complement(2502..3449)
                     /locus_tag="LP245_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBL1520141.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            3639..3908
                     /gene="rpsN"
                     /locus_tag="LP245_002250"
     CDS             3639..3908
                     /gene="rpsN"
                     /locus_tag="LP245_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBL1520142.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(4084..4446)
                     /locus_tag="LP245_002251"
     CDS             complement(4084..4446)
                     /locus_tag="LP245_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL1520143.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(4457..5578)
                     /locus_tag="LP245_002252"
     CDS             complement(4457..5578)
                     /locus_tag="LP245_002252"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBL1520144.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(5594..5944)
                     /locus_tag="LP245_002253"
     CDS             complement(5594..5944)
                     /locus_tag="LP245_002253"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBL1520145.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(6074..7585)
                     /locus_tag="LP245_002254"
     CDS             complement(6074..7585)
                     /locus_tag="LP245_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL1520146.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(7907..9259)
                     /locus_tag="LP245_002255"
     CDS             complement(7907..9259)
                     /locus_tag="LP245_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBL1520147.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(9412..10488)
                     /locus_tag="LP245_002256"
     CDS             complement(9412..10488)
                     /locus_tag="LP245_002256"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBL1520148.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            10684..12429
                     /locus_tag="LP245_002257"
     CDS             10684..12429
                     /locus_tag="LP245_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBL1520149.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(12709..13146)
                     /locus_tag="LP245_002258"
     CDS             complement(12709..13146)
                     /locus_tag="LP245_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBL1520150.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(13130..14503)
                     /locus_tag="LP245_002259"
     CDS             complement(13130..14503)
                     /locus_tag="LP245_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520151.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(14825..15313)
                     /locus_tag="LP245_002260"
     CDS             complement(14825..15313)
                     /locus_tag="LP245_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1520152.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(15335..15937)
                     /locus_tag="LP245_002261"
     CDS             complement(15335..15937)
                     /locus_tag="LP245_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL1520153.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         4467 a         3416 c         2911 g         5186 t
ORIGIN      
        1 gtttcggtct ttctttccta aatagtattc tgtcgtagca acacttgaaa gaagaacagc
       61 gccgacccac agacatagtg cagtataaaa cggggtgcta gctgaaccgt tatttgcgat
      121 tggataaagc gcattggttt gtagctcaac aggttgtgta aagaagtcac tttcttttgt
      181 tgcgtctagt ttcaataatt tgatgacttc gcctagatcg acttcttgtt cgccttttcg
      241 gatcgcgtct gctgcttttt ggataccagc tttgatattt ggccagtcat tgttgatcaa
      301 gtccgcagca gcgttcacag ctgtttcgac ttctggcatt ttttcattta ctgttgtcaa
      361 tgtaccggtg atttcatttt ttagtgctgg ccaatcattt tggataaaat cagcggccaa
      421 tcctaatttt tgctgaatga tcggtaattc attgttgtat aggtctgccc cttcattgat
      481 gccattgacg atggtatcca tatttccatt cagcattgta ttggcatcat ggatttcttg
      541 tccaattgca ggcatttctt tttgatattt ttctaaaatt gccactgcat tcgttacagt
      601 tgctttcgtt gagctgagaa gcgaatcaaa gtcgatctgg tccgctttgc tcagtgcgcc
      661 ttgtgcagtc ccaatcgtat cgatgacttg gtctagtaga gaagtgacag tggaactgat
      721 ttgacctgta ttgataccag caatgatgcc attgatatta ttaacaacgg catcaatttg
      781 atctagcaat tcatcaatag ccttcgtgtc ttcattttga acagctgtgt tcaaagcaga
      841 taggcggttt tgcagattgc ttagcaaggg ttttaattga tttagctgat caataattgg
      901 ctgtaatttc gtatttccag cacttgtttg caatttagtc aggaactcga ccagtttatc
      961 gattgcattt tgttgttgag atattccgtc aataaagccg ttcaatacat tgctgatgtt
     1021 tttcttttca tcatcagtca gcttaccatc ttcaatagct gttcttacag tatctattaa
     1081 cgaacctgtc gttgttgcca cttgtccaat tgacttcaat gtaacatcta cactgtttgt
     1141 gatgcttggt atcgcatctt tcagctgaga ggcacctgat tttgtttggt ttgctagatc
     1201 acttgcctga ttttctaaat ttttcacatc tggcaagata tcttgtactt gttggatgat
     1261 cgtcaagcct tgttttgctt catcgattcc ttggttcatt gtctcttgga tcgaagcaaa
     1321 atcgccgtcg atctctgcta gttgcttacc ggcattttgg atctctggga ttttttcttg
     1381 caaatcaagg atgatttttg cttgatcttt caactcaggc attttgtcat tcaatgcaac
     1441 gactttttca cccatctcat ctactttagg gatgtaatcc acgaattcat ttgctttatt
     1501 cagtttttcc ttgatttcag gtagttgact ttgtaattcg aggacttgtt ttgtgtagcc
     1561 gtcgatcgtg tccaaatttt catctgttga taaaatcata tctttaactt tattgatact
     1621 tactaggttc gtatcgatgt cgtaacctat ctcattgaat actttcaata aagtcgaact
     1681 ggctgttttg ataaattcat ttgtgatttg cgattggatc gaacttgctc ctttatcggt
     1741 gattttcggt gcaatcgcat tgattttttc atttaccgta tattcgattt ttggtttctt
     1801 gatatcacca ctagtaaaac tcagcagatc ttctgagaaa tcctttggca agtaaatacc
     1861 tgcgtaatac tttccggaac ggactccgtc ttctaattgt tcttttgaat caacgaattg
     1921 ccatcctaat tgtttatttt tatgaagcga ttcgatgact tgctccccaa tggccacttc
     1981 tttaccttga aactctgctg gcttgtctgc actgtaaaca gcaattggca gctctccagt
     2041 atttccatat ggatcccata atgctttgat gttaaaccac gcatatagcg aagggatgat
     2101 catgatcgcg atgatcagaa gtgttgcaat cgggtttttg aaaatccgtt tccagtcaag
     2161 caaatataat cgaagcgtat ttttgattga ctgcatagtt ctcccccttc ttcttttttc
     2221 agctgaatta ctttaccatg tatttcatac ttttttcaat cggctttttt caaaaaagtc
     2281 gaatttttgg acatatcacg gcaattgtct cattgtaatc tcttacatat tgagaaataa
     2341 ttaaggatta cagcctttac tttatcatga aataaaaggg aaagataatt ttatgccaaa
     2401 gtttttatct attatacgta tacgcaaaaa agctaaaaca ttttttgtct ttgcccctac
     2461 aaaaatgttt cagctttttt cgttttttat tcctgtattt cttatttttc gaatgacagg
     2521 atgattttcc cagcaggagg atgtccttca actagctgat gtgcttggat gacatgctta
     2581 agtgaagcag acagattcat tgaaataaaa acatgaaagg ctcctttttg gtaggctttg
     2641 attatgccag caaaggcttc tgcatctaga tattcctttc ttggaacaaa cgattcataa
     2701 aagccttcct ttttttgccg caaatctaga tctgggaggt catttaatgc aacatacctg
     2761 ccgcctggtt tcatgatctg gatgccggtt tctcctttga tacttccttt cgtcgcatcg
     2821 attacaaggt ctgcctgatc agcaaattgc agacctggat ttgttttatc ataagcagca
     2881 aatgctgaag ctcctaattt ttttaccttt tcctcatttt tactggatgc actggttaag
     2941 attcggattc ccttttcatg gagaagctgg atcagacttg acccgaccgc acctgatgct
     3001 cctagtatca ttacagtatc tgtcggctgg atttccgtca aatggttgat tagattataa
     3061 gccgtaattc ctggcgtgac cattccggct gcttcttccc aactcatttt atctggaatt
     3121 tttgctactt ttgctgatgg caacacgact tcttctccgt aagtcccgcc gactgcatgg
     3181 acagctactc gatcacctac atgaacagtt gtgacatctg aaccaatctc tgtcacaata
     3241 ccagcgccat cattacctgg tacataaggg aatttcaatg ttcgtatctc tttcatttct
     3301 cctaaacgca aggcaacatc ataaggattc acactgaatg cttttatttc tacacgaaca
     3361 tgtccagaac cgacttctct gggatgagca tcgatttctt caaaaacatc ttgtgcttct
     3421 ccgtaaccgt taattgcaaa tcttcgcatg gtcaccatct ccctttttct ttaagtttac
     3481 gtttatgtct ttattttgac aaaaaaaatg tcttttcgtt ttggcgcatg attcaaaaca
     3541 aaatagttgt cttttttcgc gtaacgtgtt aaattattta tctaaaagcg taaagattac
     3601 gatttacgct aataaaaaat aattggagga atttgttgat ggctaaaaaa tcaaagattg
     3661 ccaaagcaaa aaaacagcaa gaaacgattg aacgctatgc tgctttacgc caggaattaa
     3721 aagcgcaaaa agattacgaa ggcttgcgta aacttccttt agatgctcgt ccagaacgat
     3781 tgaaaaatcg tgatttaatc gatggacgcc ctcgcggata catgcgtaaa ttcgggatgt
     3841 cccgtataaa attccgtgaa ttagcacata aaggtttgat tccaggagta aaaaaagcca
     3901 gctggtaatc caagtctggc tgtaatgtaa aggaggaggg cgcatggacc actccttgga
     3961 tcatcaaaaa agatacgttc gcttcttcta gcagaaatgc tggtactaga agcagacgta
     4021 tcttttttta cgcacagctg gtcctttttt atatgtaaag gctgcatggt tacttcgcta
     4081 tatttattta gtaacaggag tcagtgcttc gatacccaca ctaattttca atgctcggtc
     4141 aacttctgcc ataatgggtc gatccaaatg gcagaccttt tctttcaatc ttgatttatc
     4201 gatcgttctg atctgctcca acaggataac ggagtctctt tctattcctg ttccagtagc
     4261 tttgatccca atgtgagtcg gaagcttagg tttagccatt tttgccgtta tggccgcaac
     4321 aatgatcgtc gggctaaaat ggttacctag attattttga ataaccaaaa ctgggcgtgt
     4381 tccgccttgc tccgatccca cgactggaga aagatcagca aaataaatat ctcctctttt
     4441 taccatagga tcctccttat tcttgatatt ctcttggtat ccgctgtcct aatccgcaag
     4501 ccacttcata gtggatcgta cctaattgat ctgctatatc ctgcatagtg atttctttgt
     4561 ctgcattttt gccgataagc gtcacttttg ttccgacagg aaattcttga ggcaatcgga
     4621 tcatcagttg atccatacat acacgcccaa tcgtttcaca gtagttccct tctaccaata
     4681 gagaaaaacc ctgcatcttt cgtggccagc catctgcata accgatcggt atcgttccga
     4741 tccactctgc ttcaggagtg atatatgttt ctccatagcc gattccttca cctgctggga
     4801 gttttttgac ttgaatcaat tcagaaacca gctcaagtgc tggctgcaat ggataaactt
     4861 ccggtagtgc gtgcccagag ggattaagtc cgtacattgc tactccataa cgaatcatat
     4921 tgccgattgt ttcatcatgc cataaagccg ttgcactatt gctgacatgt acatatcgag
     4981 gaagttcggg aagttttttc agcacttcta taaagcgttc tttttgcaga ttccaatatg
     5041 tatcatctgc ctgatctgct gtagaaaaat gggtaaataa accttcccat tctaatacac
     5101 gactttcttt gatgaatgca gctgcctctt ttacttcttc aggtgtacaa aatccgatac
     5161 gacccatccc agtgtctgct tttagatgaa tcgaaagagg cgtctctagc ttacttttct
     5221 ctaaaacagc agctgctgct tgcaaccatt cccgtgtacc tgcagttact gataaatcat
     5281 gagcaacagc tacagtcagt gcgtcgtaag gaaccatatt caagataagg atgggctgag
     5341 taaatccagc ttctctcaac tcgactcctt catctaaatt tgaaacacaa aagcccgaag
     5401 ctccacctgc aactgctgcc tcagctgttt caatagctcc atgaccgtat ccgttcgctt
     5461 ttactactgc aaacaattct tttccttgcg gaagtcttgc aacttcattt gctacatttt
     5521 cagttatagc ttttttatgt atcactgctt tcgttgggcg gtgccaagcg acaaccatcg
     5581 tttttccttc tttctagtct tccaaaataa tttgtgcaaa agctgtttca tttgtatgag
     5641 taatactgac ccatacattg ccttcatgag gtgaacgcgt cacaacaggc tgaccatttt
     5701 cattttttaa aatctcgaca tcttgaaagg taacttttcc gatcccagtt ccccaagctt
     5761 tagagaaagc ctctttgcaa gcgtaacgcc cgcctaaaaa ttctacttgg cgatgaaaag
     5821 gcaaggactg gaatagtttc atttcatcag aggtcaagat tcgtgcaatg aattttggtt
     5881 tttcttcgat cagccgagtg atcctaggaa gttcgactgc atcgatccca attcctttta
     5941 tcatatgctt ttctcttttc aataaattta gaacactctc attctaccaa attataacca
     6001 ttttgccaca aataagtcca caaataacaa aaatgaaagt ttctcttaaa aaagagaaac
     6061 tttcatttta tgtttaatcg ttatttgaac ggattacaaa tccgcgtttt ttatcattgt
     6121 gacgtttacc gccatctttt tggctgttat tatttttgct ataaccgcct tttgatttgt
     6181 ttccacgata attaccgccg tcacgacgat tacggttgtt tccgccacca cgtttgccat
     6241 ttttattgta tccttttttc tgcattggca atgggcgttc tggtgtgatc ttcactggca
     6301 ctgcatcagc tggatctttt gctgtcgttt ttagcaaaag tgcaactaaa tcttgtgcag
     6361 aatattcttc taataattta tctgctgttt gcaggtattt atctagacca ttttctgcaa
     6421 gttttgtttc gatttgttca actgcagcac ctaattgacc tttgaatgct tctttttcgg
     6481 ttggtggacg taaagtcgtc atccgttttt tcgtcaagtt ttcaatcaca tgcaagtagt
     6541 ccatttcatt tggtgtaacg aaagtcacag acataccgcc ttttccggca cggcctgtac
     6601 gtccgatacg gtgaacgtag ctttctggat cttgagggat atcatagttg tacacatgag
     6661 tgacacctga aatatctaat ccacgtgcag caacgtctgt cgctacaagg atatctaaat
     6721 gaccgctctt aaatgaacgc aatacgctca ttcgtttttg ttgagacaaa tcgccatgga
     6781 ttccttctgc acggtaaccg cgtgcttcta atccgcgtgc caattcgtct acacggcgtt
     6841 ttgtacgtcc gaagacgatt gttaattcag gtgtttgaac atcaaacaag cgagtcatga
     6901 tatcgaattt ttcgtattct tttgcgcgga catagtattg atcgatcaag tcagctgtca
     6961 tttctttcgc tttgatcttc acatgatgtg gatttttcat gaatttaacg ccaatattct
     7021 tgatagctgg cggcatcgtt gctgagaaaa gtaatgtttg tctttgatca ggaacttgtg
     7081 aaatgatttt ttcgatatct tccaagaagc ccatattcaa catttcatct gcttcatcca
     7141 aaactaatgt ttgaacggtt ccaagtttca atgtgtggcg gttaatgtgg tcaagcatac
     7201 gtcctggtgt acccacaacg atatgtggac gatctttcaa gccacggatc tgacggccaa
     7261 tatctgctcc gccgtaaacg gcttgtacac gtactttttt gtcgcgccct aaacgatata
     7321 attcttcttg tgtttggata gctaattcac gtgttggtgc gataactaaa ccttgtaatt
     7381 cgtgacgatc tggatcgatt ttttctaaca ttggtaatcc aaatgcagct gttttccctg
     7441 tacctgtctg tgcttgtcca ataacgtctt ttccagctaa tgctagtgga atcgtttctg
     7501 cttggatagg cgttgcttct tcaaaaccag cgcgttcgac tgatttcaac aattctggtg
     7561 ataattctag ttctttaaat ttcaaatgaa tcctcctata tggttgttaa ctgaggatgt
     7621 agcttttttg ctaccccgtc gatttgttcg gtcaaagtgt attgtttctt tttgacagtg
     7681 gccacgcacg tttttatcca ttcttagccc ctgtggcacc accgaaaaat cactttgcga
     7741 agtttaggca ttagaaaagc caaacgggtc gcgttcagct ttatcattat tatgacatct
     7801 ggcttcaaca agttgtttct atggcaaaac cagtccaatt tctcttcatc tttcggcaat
     7861 aggttattct aacatagttt ttcgttttct gcaagtttac agatttttat ttcatttgct
     7921 gaagttgttc taccacttca aataagccca tgctgttgct gccttttagc ataatactat
     7981 ctgttgctgc aagattttgt ttgatagcat caatcaattt attcttttct ttttcaaaat
     8041 agaacacagg tagttggggg tatttttggt tcaattcttc ttttagtgca tgcatttgtt
     8101 ccccataaag gaaaatcatg gcgaatttct caggatcgat atgttcactc atttgcgcat
     8161 gcatatttaa agactctttc cctaattcca gcatatctgc taacacagcg attctgcgtc
     8221 cttttgttgg cagattttta aaagtatcta ataccagtcc catggctgtt ggatttgcat
     8281 tgtagacatc gctcaaaata gctgcaccat ttcctgccgt tagccattcg gttctgtttt
     8341 gagtgataga aacatgggcg agcccttggc gtatctcagg tatggacagt ccaaagaagc
     8401 gcccgatcgt atacgcaatc aaagcattcg ttacattata acttccaggc agcgggatcg
     8461 taaatgtttc tccttctact acaaaatcgg tttgtgcttt tccttttgct gtcacttccg
     8521 catgaacatc gccatttcca ataccgaatg ttgtgactgt ttgtactaat gttgccgtta
     8581 aaggtgtcag caacggttca tctgcgggca caacgagtaa tccgtctgat acaagtccgt
     8641 cagtgatttc cattttggct ttagcgattc cttctcgcga cccaagattt tctatgtgtg
     8701 cttcaccgat cattgtgatt gctgcagctt ttggttgagc cataagtgaa agttccgtga
     8761 tttcattggc gtgatccatg cccatttcca aaacgatctt ttctgtatct tggggcatgt
     8821 gcaaaatcgt gtaaggaaga ccaatattat tgttgtaatt tccttgcgtc ttatatgttt
     8881 tgtatttttc agacaagaca gacgcggtta gatctttcgt ggtggtttta ccattgcttc
     8941 ctgtaattgc aacgacttct gcgcctactt tttccaagta ataggttgcc aattgctgca
     9001 tggctttcaa aggatctgct acaggaataa ctggaaaatt ttttggagct tgttcaacag
     9061 gcaagctcca aaatgaagca gatgctccgt ttgtgatcgc ttgctggata aattcatgtc
     9121 catctcgcgt accagcaaga ggaacgaata aacttccttc ggttatcttc cggctgtcaa
     9181 attcgacatt ggtaatcttt gtcagtgcag agcattcgct gcccacggct tgtgcaattt
     9241 cttgtattgt tagattcatt gagatctctc ctaaaaaagg ttgtgaaaaa agcgtttggc
     9301 ctaaacggcg ggttcgcatg actctcactt ccaagtaaat ttctctattc gtatttagaa
     9361 gctagaatga acgcggttac gcaatcactc cagcctcttc tttatttctc tttattcatt
     9421 tttttcaaaa aaagattgac gctgatggta tcgattcatt cctaactgga tcagttcttc
     9481 aatcaaatca ccgtatttca agcccatatt ttcccataag agtgggtaca tactgaactc
     9541 cgtaaatcct ggcatagagt ttaattcatt caggaataat tcatttttat ttgtcaaaaa
     9601 gaaatcgcac cggctcaatc cgcttccacc taacatcgtg taagctaact tcgcgtactc
     9661 ttgcgctttt tgataaactt cttctggcac ttcggctgga atctgcattt cgattttatt
     9721 attgatatat tttgcttcat aatcatagaa tgctacgtct tttacgactt caccaggcaa
     9781 agtcgtccga acgtcttcat ttcctaatac agcaacttcg atttcgcgcg cttcaattcc
     9841 ttgttcaacg attgctcgag aatcatactg ataggctgtt gctaaagcat tttgcagctc
     9901 ttctcggttt tctgcttttg taatgccgac actagaaccc atattcgccg gtttgacaaa
     9961 catcggataa agcaaagaac cttcacattg atcaaatact tttttaggat tttctttcca
    10021 ttgattctta agtactggta cataaggaac ttgcggcaca ccagcagctt gtaaaatata
    10081 cttggtcatg attttatcca tggcacatgc actggtcaat acgcctgcgc cgacataagg
    10141 catattcaat gtctctaaga agccttggat cgttccatct tccccgtttg gcccatgtaa
    10201 aactggaaaa acgatggctc cttcttcttt gatttcgccc ggattgatca cttttcctgt
    10261 aaagccttcc tctgtctgtc cacttgggtc ccatgaaaga tgcaagacat ctttgctggc
    10321 aggtttttct gttagtaatg gacctttgac ccattgtcct tcttttgtaa taaatacgag
    10381 ttgaacttgg taataattat aataaatggc atttaaaact gaaaatgcgg aaagaatgga
    10441 cacttcatgc tctgcgctgc gtccgccata tagtaaagta atcttcaaaa gattgtcctc
    10501 ctgtattcta aatcgttcag tgatttactc tcatatttta gcacaaaaca aaaataaacg
    10561 aataacttat ttataaaaaa acgagccagc ttctaaaaga acgagcgtca tttatttttt
    10621 gtcagctaga ttatttgtcc cgttttttat aaaaagttat gataaagaaa aggagggatg
    10681 atgatggcgc aaacaaatcc acgcagccgc ttggcagaaa tcattcgagt gttcatcaat
    10741 tacaatgtag tgccaaactt tgtacagcaa aaaaatcccg aacaggtaaa aaaagccttt
    10801 gaagaactag gccccacctt catcaagata ggacagatgc tttctgttcg agaagatttg
    10861 ctttcttctg ccttcactca aacattcaaa acattacaag atagtgtacc tagcgacaca
    10921 ttttcaacgg tcaaaaagac gatcgaaaca gaactttctc tttcattatc agatatattc
    10981 gatgattttt caaaatcgcc ttttgcctct gcttctatgg ggcaggctca tcgtgccaag
    11041 ctgaagaacg gtgacgcggt agtcgttaag atccaacacc ctaacatcgc cgaagagatc
    11101 cgacttgatc ttcaactatt tgaacgagcg atccctttga tcaaatacat tcctgaaact
    11161 agcgtagttg atctaaaagg ggtactccaa gaagtaaaac gttccttgat caatgaaatg
    11221 gacttcttaa aagaaagtca aaatggcgaa caattctatc aaaagaacaa tggctggaaa
    11281 gagatccgca gccccaagat ttatgacgct ttttgttcga aaaaagtgat cgtgatggaa
    11341 gaaatgtctg gtaaaaactt gaatcattta atgaacgccg aaaacaaaac tgaaactttt
    11401 atcactggaa ttcaaaacaa gcagctgaaa caagaagttg caaagctttt agttgagaac
    11461 tttatgaaac aggtgtttga tgatggtttt ttccatgctg atcctcatcc agggaatctg
    11521 ctattccatg tactaacaaa agaagaacag acacaagcta gccgaaaaac tgaaacagtc
    11581 catgaaaaag agttcggttc ctttgctttt cgagcctcca cttctgcaga agaccctgtt
    11641 gcgccatata ccatcaacta catcgatttt ggtatgatgg ggcatctttc tgcaggactt
    11701 aggcaaaaac tcacacaagc cgttttagcg ctgtatacga aagatgctta tcgaatcgaa
    11761 aaagcggtcc ttcgactttg tcagcaagaa ggctcgtttg atgaaagtcg gttccaccaa
    11821 gaactgacaa gttttcttga acagtattat gattctccta ttgatgaaat caacttgcaa
    11881 gaagtattca cacatgtcgt gacgatttgt catcaaaata atctgcagtt cgatcgtgat
    11941 atcacgcttt tgctgaaagc atttgggaca ttagaagggg tgatccgcgt cctcgatcct
    12001 gaagtttccc tcatggaagt cgcttcgcct tttgctcaac attattttct cactcatctg
    12061 gatgtagaag atacattgaa acaaagcgga ttagacttat tggaagggat gaaggctgcg
    12121 cctaagatcc ctcaacagct ccaccatcta ttagaaatgt ggacttcggg acaaggaaaa
    12181 gtcaatttgg aattgaaaaa gcaagacaaa ttattgagca ggatcgaaag tatgatcaat
    12241 cggcttgttt tcggtatgat tttagctgca ttgatcgtag ggtcctccct gcttgtccaa
    12301 gcagcacctg tagaaaacgc agaggtcgtt tccttattag ggatatttac gtatgctatt
    12361 gccgcattcg tcattatttt tttggcaatc gatgcattga tccaaatgta taagaagagg
    12421 aaaaagtaga aaaaggttgt gacagaaaga atcagcttca agaaataaga aggggtttta
    12481 cataaattgt ttctcaaatt tttgtgaaaa ttcggcttat ttttcgaaga ggctacttct
    12541 gaaacaccga gaataaaaaa tgtgaaaaag ctattctgca cccagtaata agaacaatca
    12601 aaaagggaac atggaacaca tttatcctgt ttccctgttc cctttttgat gtattcgagc
    12661 ataaataaaa taccttcgtt acctactatc ttctgtactt ggtaaacctt agtcaattgc
    12721 cttttttaac gcttgacgaa aagacatatg atctttctcc gtaaagggtt ttggaccctt
    12781 tgtccttatg ccagcttttc ttaactttcc actatgataa cgttgttcta gaagcgtgcc
    12841 gatattcgct tcgtcaaatt cttttccaga gtgatggaac actcgcacac ccttcggcaa
    12901 tacaagtgaa gctaaaccat aatcttgcgt gatcaaaaag tcattcttct taaccatacc
    12961 gacgatttta taatccgcac tatcagctcc gcggtctacg tagacgattt ggacatgatt
    13021 agcgtattct ttggtcgtat aatggtccac actggtcacg ataaccacgt caagaccata
    13081 ggattctcct aattttatga catcttcttt tactggagaa ccatctccat caatgaatag
    13141 cctcattctt tttcgccttc ttccataaat gataaacagt tactaatccg ctcagtaaaa
    13201 gaccaacatt gatccatttt gccaagataa gcagttgtac actttctatc ggcactgatt
    13261 catggttcag cgtgatcaat aatagatgga ttggctctcc catttctttt gctaaaacaa
    13321 acaaaagcgt catcaataaa aactggtgga tcacactccc tttattttga gtagtatact
    13381 tgacaacgat ccggcgatcc attggaatag ctgtatcagt ttgataatat tccttattta
    13441 gccagctgcc tgttactacg tgccagaaac taagcagaaa gacacctatc gcaaaaccat
    13501 ttggaatcaa gaggaccaat aaagaagaac tcagtccaag caattgcata gccaatggag
    13561 accatgttaa acgtttcaaa atccatggtc cgactatttt tgctgcaatc aagcctgctg
    13621 cataaggcaa atacataaaa atcgaaagtt tttctaatcc gtacagtatg ccaacataaa
    13681 aactgctaaa taaaaaaagg aaattcccta gcattccatt tagaaaagta aacagattta
    13741 gccagcttgg caacttccat tccttcttct ggtgtcctaa aacaaacacg aacaagatga
    13801 acagcagcaa gaaaccataa atagcaagat caaaaagcct ttcatcgaat aacaatcggg
    13861 catttctcaa aagaaacaat aagccaaaga atatcaaaaa taaaacaagc tctcgcgtag
    13921 ctaccagatt tcttttgatg tctttgaaat ccagttcgta acgcggataa tgactaaccg
    13981 tatggtaggc catgacgtaa aaaagtgtat aaatagtaaa gcttgctgca atctgagtcg
    14041 gtgcaggcaa ctcaatcgct tgatacagga gaaatagcca gatagctgca aataagtact
    14101 ttttcccatc catattgata aaaccttgcg tcttttcgtg aaaattgacc gtggtattag
    14161 caggtacaag ccatgctgca ctcagcccta gcaaaacact tgaaaaataa aataaaggaa
    14221 aataaaatac gcctaatatt ccaagcaatg aaccagcacc accaatcagc agagcgatca
    14281 tcagcaacgt gtaactatct agaccaaatc gtagactgtt gactaaaaat agtccagtca
    14341 tccgaaaggc ataaaacagc gtaaatggca aaatcgtcag ccaattatgc gagtctgtta
    14401 gtcccaaaaa taaaagataa ggaataaaaa taaccgtgtt acttaagata aagggcgttg
    14461 tttgtgtaaa attacgccca aatcgtttga gtttttcgaa catgacaatg gctccttaaa
    14521 cagtcttata actaatctgc tcttcgattt tagcattaaa ggggaaataa accaatttta
    14581 cagaatatat tcttgtaaaa aaaaatacag aaagaagcat aagcttcttt ctgcattttt
    14641 acggtacttg attactcaag cagacaagcc cttctccaca aaagtcttgc ccgacacccc
    14701 tgcatccggc aggtgataaa gatagaaatc aattatcctg tgcctccaaa atcaattagg
    14761 agctctgtaa accagagtcc ttctcgaccc gtcgcataaa tttactttaa cacagttcct
    14821 atgtttatgc gagagctttt ttcattttat aatcgaccat ttgaaatcct tgaccgatat
    14881 ctgaaataag ttcttctgta atctcaaatc cttcatgctt ataaacctcg attgcttgat
    14941 gattcccctg attcactcgc aaaaagatct ctctttcctt tgtttgcgca gcaagttctt
    15001 cataccagcg aaaaactgaa gaagtcaatc cttgaccacg tactttattt agcaaatata
    15061 atttacttaa ataaattttt ccatttatct cttcataagc agtgtaaccg acagtctttt
    15121 cttcgctttt taataaaaag taggacacac cttctgtcag ttctttttga atctgttttt
    15181 ttgactgata agttttcagc atgtaatcca cttgtttttg accaatgatc ggcacaaaag
    15241 cttccggcca tacttcttgt atgactgcca tcagctcatc cagttcattt tctgttactt
    15301 ttattttttc catacaccca cgtccttttt tacattataa atgaccttgc gcttgatgga
    15361 ataaaaagag catgatcatg ctatacacac ccaccgacca tggtttcaag aaaatcacaa
    15421 tctgcataaa ttccctaaaa gataatttcg tcaaaccagc tactagacag atcaagtcgt
    15481 ctggcgcaaa gggaagcagc aaggtaacaa ctagtacttt tttaatatct ttcgtttttc
    15541 ttgtcagcaa ttcatcaaat ttctgatact tttttggcga taaaataagc tggacaaagg
    15601 ctacgccata gtaacggaca agcaaaaatc cgattgcttc cccaatcact aggccaatac
    15661 aactatataa aagcccaaat ccattgccaa acatcagcat gcccgctact gaggagatcc
    15721 ctcccggcaa aataggaatg atcacttgga tcacttgcaa cagaacaaat atcatcactg
    15781 catacttgcc aaattgctgg ataaacgctt gcaaagacgt gctcgatcga aaaatcccat
    15841 gatgataagc ataaagaatc aacacaaaga aaaaaaacag accaataatg ggcatgatct
    15901 gaagacattt ttgtaaaact gatccttttt tagacatcta tattccccac atcttttttc
    15961 atttattaaa actgcctcct
//
LOCUS       DAFEEZ010000066        15870 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000066
VERSION     DAFEEZ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.069"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(23..493)
                     /locus_tag="LP245_002262"
     CDS             complement(23..493)
                     /locus_tag="LP245_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBL1520154.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(652..1110)
                     /locus_tag="LP245_002263"
     CDS             complement(652..1110)
                     /locus_tag="LP245_002263"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBL1520155.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1281..2425)
                     /locus_tag="LP245_002264"
                     /pseudo
     CDS             complement(1281..2425)
                     /locus_tag="LP245_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
     gene            complement(2438..3355)
                     /locus_tag="LP245_002265"
     CDS             complement(2438..3355)
                     /locus_tag="LP245_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBL1520156.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3783..4346
                     /gene="efp"
                     /locus_tag="LP245_002266"
     CDS             3783..4346
                     /gene="efp"
                     /locus_tag="LP245_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBL1520157.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4447..4617
                     /locus_tag="LP245_002267"
     CDS             4447..4617
                     /locus_tag="LP245_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520158.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            4832..6091
                     /gene="lysA"
                     /locus_tag="LP245_002268"
     CDS             4832..6091
                     /gene="lysA"
                     /locus_tag="LP245_002268"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBL1520159.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6078..6878
                     /gene="dapF"
                     /locus_tag="LP245_002269"
     CDS             6078..6878
                     /gene="dapF"
                     /locus_tag="LP245_002269"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBL1520160.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6881..7762
                     /locus_tag="LP245_002270"
     CDS             6881..7762
                     /locus_tag="LP245_002270"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBL1520161.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7759..8475
                     /locus_tag="LP245_002271"
     CDS             7759..8475
                     /locus_tag="LP245_002271"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBL1520162.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8481..9176
                     /gene="dapD"
                     /locus_tag="LP245_002272"
     CDS             8481..9176
                     /gene="dapD"
                     /locus_tag="LP245_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBL1520163.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9192..10193
                     /locus_tag="LP245_002273"
     CDS             9192..10193
                     /locus_tag="LP245_002273"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBL1520164.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINENRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10190..11551
                     /locus_tag="LP245_002274"
     CDS             10190..11551
                     /locus_tag="LP245_002274"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBL1520165.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11511..12662
                     /locus_tag="LP245_002275"
     CDS             11511..12662
                     /locus_tag="LP245_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBL1520166.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12637..13806
                     /locus_tag="LP245_002276"
     CDS             12637..13806
                     /locus_tag="LP245_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL1520167.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            13981..15360
                     /locus_tag="LP245_002277"
     CDS             13981..15360
                     /locus_tag="LP245_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1520168.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15641..15870
                     /locus_tag="LP245_002278"
                     /pseudo
     CDS             15641..15870
                     /locus_tag="LP245_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5187 a         2799 c         3378 g         4506 t
ORIGIN      
        1 atcttttttt atttttatta agttaaagaa cggattcaat tgcagcggtc attttcaatg
       61 gagaagtttg tggtgcaaat cgttcgatta ctttgccatt tctatcaatc aaaaatttag
      121 taaaattcca ttttattgct ttagtgacag taccaggagc ttcattttta agataagtaa
      181 aaagaggatc tgtattttct ccatttacgt caatcaattg atgcataggg aaggtaacgc
      241 cataagtggt tttacaagct tctgctgctt cagtcgctga atctagctct tgtttaaatt
      301 gattggaagg aaagcctaag ataaccagac cttgtgtctg ataagcttgg taaagttctt
      361 ctaattgttt aaattgaggt gctagaccgc attttgttgc agtgttaaca atgattatcg
      421 gtttgcctgc atattttttc aatgaataga cagtgccgtc ttctaaagta gtttcaaaat
      481 tataaataga cataaagttt tctcctttct attttatata ataaaaagag cgctaaactg
      541 aaaactagct atttgttttc ccgtttagaa ctcttttcag acaataaata tttaataaaa
      601 tacgaagata agatagctat attgcttctc atctttacgt tcttttagaa actatgcttc
      661 tacttcagac cattcatcgc gttttgctaa aaattcacga gccaaagctt gtgcaccttc
      721 tagtgtatgg ctggcagccc agccacattg tgtttcattg cttgcaggta cttcagtagc
      781 ttcaagaaca tctttcattg ttgcttcaag aacatctaaa atgtcttcgt agctttcatg
      841 attcaataca gtcaagtaaa agcctgtttg gcatcccatt ggagaccagt ctacgatgta
      901 atctgcgtga ttgcggatta gttcggcagt caagtgctca agtgaatgta gacttggcat
      961 gtccatgtgt tctttatttg gttgtttaaa gcggacgtcg tatttaatga tgacatcgcc
     1021 atgcgcaccc gtttttcgat cagctacacg tacataaggt gctttgactt ttgtatggtc
     1081 aagattaaaa ctttcgacat tcattctcat ttgtaagact cctatctgtt tgttcattcg
     1141 ttttgatgct tttcactaaa gaattattta gtgaaattta caaaaacgtc tttctacttg
     1201 attctaacac ttatcgtttc caaggtgtag caatctgaaa tattttttag atttttctgc
     1261 taagtcgttt attgggactt ctagttcttg attctgtcaa atgcctgagc taaatcgttt
     1321 atgagatcct gaccatactc aattcctaca gaaagacgga tcaagccgtc ctttatgcca
     1381 gcctcttctc gtttttcttt tggaatagac gcatgagtca tgacagaagg aatttccact
     1441 aaactttcta cgccacctaa actttctgct aaagtaaata gttggagtga ttcaacaaat
     1501 ggaatagcag attcttcatt ttttaaagta aaagaaatca ttccgctaaa gccgctcatc
     1561 tgctgcttag caactccatg gagttcatga tcgggtaatc ctggatagta gaccttttct
     1621 actgctggat gagaaaatag aaaatcagct accacaaaag catttttttg atgttcctcc
     1681 atacgaacac ttagtgtctt gattccgcgc tgaagtaacc agctatcttg gggaccaagt
     1741 acggctccga tagcattttg gtaaaatccg atctgatcgg ctagatcttt tggttagaag
     1801 tcactaaacc agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa
     1861 cgatatcaga accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag
     1921 caataactat caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct
     1981 ttagaagcgg attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt
     2041 gttctatttt atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa
     2101 gaactttgtc aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat
     2161 cgccagcttg aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga
     2221 atcctcgaac accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat
     2281 taccagatct tgaatattca tattgtttag gctggccgac gccatcttgc cgataagtgg
     2341 atgtttgata aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt
     2401 ggatcaattt tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata
     2461 aatagcggtc tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac
     2521 gaatttctct taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt
     2581 gttctcgtgc taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct
     2641 gattgattga aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt
     2701 cgtgaggggc tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc
     2761 gaatgtcggg atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc
     2821 caattcctgc tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta
     2881 acgtatgata gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt
     2941 ttgatatctc ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac
     3001 taggagaatg gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa
     3061 acttctctgg aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc
     3121 caattcctgt atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt
     3181 gggcaaatcc ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat
     3241 ttaaatattc tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt
     3301 caaagcgata aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatgtggg
     3361 cctcctaaaa aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca
     3421 tagagaaaaa ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa
     3481 ttaatagaca tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat
     3541 tgtttttggt tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc
     3601 atgaaaaaaa ataaaagtca aaggcttgaa agaaaaaaat atttcgatag catcgtttac
     3661 ccgtgtttat ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt
     3721 ttctggccgg ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa
     3781 taatgatctc agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga
     3841 ttaaagttct ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga
     3901 aactgaaaga tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat
     3961 ttgaaaaagc acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag
     4021 ctttcttcat ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag
     4081 aagaaatgaa atatatccta gaaaacatgg aagtaaaaat ccaatttttc ggtagcgaag
     4141 tcatcggcgt tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca
     4201 tcaaaggtgc aacagtcact ggttcaggta agccagcgac aatggaaact ggcttagtag
     4261 tcaatgttcc tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt
     4321 cttatgtaaa acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga
     4381 gcttgacctc ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc
     4441 agcaaattga aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa
     4501 aagctagaga aagaaaaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt
     4561 gaaaatatcc gaactattcc gaactatatt gaagcgaaaa tattttttca tcactaaata
     4621 gtgttgaatt tatgttttta tgtataaata gcttctaata gttcgggtat tttgttttta
     4681 taaccatttt tattcttatt tttaaaaaaa tatttcgaaa tatactagac aattcagaaa
     4741 attttgttta atattattcc aataaaattc aaatctttat caaatgaaat tccaataaaa
     4801 acggaaaaaa agtgaaaaga ggaatgaaaa aatgacagaa ttgataattg gcggagtcac
     4861 agcaagcaca ttggcagaaa agtataagac acctctgtat gtgtatgatg aagaaaagat
     4921 gagacaaacg atgctgtcat tcaagcgagg ctttgtatcg aaacgttttg atacaaaagt
     4981 gctttacgcc tctaaagcat tccaaacgat tgagatgctg catttagttc gtgaatatgg
     5041 attcgggcta gatgttgtca gtggtgggga aatctatacc gctttgcaag ctgattttcc
     5101 tagagatact atctacttcc atggtaacaa caagacgcca gaggaactga tctatgcact
     5161 tgaaaatgat ttgttgcata ttgttgccga taatttgatg gaagttgaat tattagcaga
     5221 attaagccaa cgctatttaa aaaaaatctg tatcatgctt cggttgaatg tcggagtaga
     5281 agcacatact catgaatata tcgtcactgc gcatattgat tcaaaattcg gcatgagcta
     5341 tgaaagtaaa gagtgccaac aagcccttca gttgataaaa gaaagcagct atctagagtt
     5401 agaaggattt catgctcata tcgggtcaca aatttttgat gttactgctt ggttagctga
     5461 aatcgacaaa ttgacgaatt acttaaccga ttttgaccaa cctctttcct tgaatcttgg
     5521 cggagggttt gggattcgtt atacacaaaa tgatcagccg atcccagtcg aagaggcact
     5581 aaaaaaactg attgaatata cggaagaagc tttggaaaaa cgaaaactga ccattcgtca
     5641 attactgatc gaaccgggta gaagtattgt tggagaagct ggtacaacac tatacacgat
     5701 tggtttcatc aaaaagacac cacataaaaa atattacttt gtagatggcg ggatgacaga
     5761 taatatccgt ccagctctgt atcaggcaga atacgattgt gatttagcag caaaactgtc
     5821 ggaagaaaaa acagagaaag tgacgattgc aggaaaaatg tgtgaatcag gcgatgtggt
     5881 aattaaagaa gcttatttgc cgaaagcaga atcgggtgat cttttagctg tttattccac
     5941 gggagcttat ggatactcga tgagcagcaa ctacaatcga gcgacacgac cagcagttgt
     6001 ttttgtcaat aatggccaat caagactgat tgttcgcaga caagcatttt ctgatctact
     6061 aaggggggaa gtttcctatg atccttcata aatataatgg ctgcggaaat gattttatct
     6121 tattagatta cgcagaagac acagattata gtcaattagc cgcttcttta tgcacaaaag
     6181 aaaaatatga tatagacgga ttgatcgccg taaaaatcga tccgttggaa atgatctatt
     6241 acaacaaaga tggcagccgc gcgccgatgt gcggaaatgg cattcgctgt tttgctcgat
     6301 acgtaaatga tcagaacatg atgaatgaac aggaattcaa cgtagagaca ttagcaggca
     6361 caagaaaaat tacggtgttg gatccctcac ctttttattg cagcgtagat atgggagtgc
     6421 cagatgattc tccggaaaaa atcaaagcta atcaaactta tccaataaaa aaccaggaaa
     6481 tagagatcaa tggtgaaaaa gtaacgatca ctagtttatt tttaggaacg attcataccg
     6541 ttgtttttgt tgaaaatgcg cgtgaggaag tctggagaaa aagaggtgaa ctgatctgtc
     6601 atcatccttt gttcaaagaa aaaaccaatg tcaactttgt agaagtagtc aatgaacaag
     6661 aattgatcgt ccgtacctat gaaagaggag taggttggac acttgcttgc ggtacaggtt
     6721 gctgtgcctc ttatgtggtt gctaaggaaa ctgggaaaat ttcagcagat caggtagttg
     6781 ttcacttgga acaaggagac ttgatgatct ctggtgagga tgcgatacaa atggctggcc
     6841 cagcagttca tgaatggaca agaatattgg aggaatgaag atgataaaag gttcgatcgt
     6901 ggcgctgatc acgccgatga atgaagaggg atcagtagat tatgctggtt tggaaaaatt
     6961 gatccaattc catttagatg aacaaacaga tggattatta gttttaggta caacaggaga
     7021 atcttctacg ctcacacaat ctgaggagga gcagatcctt caactgacag taaagaaagt
     7081 ggctggccgt gtgccggtga ttgcaggagc tggaacgaat aatacgaaag aaacgattga
     7141 aaaagcgaag cattttgctt ctttgggggc agacgcactt ttggtcatca ccccttacta
     7201 caacaaaaca agtgatgcag gactagctgc tcattttaca gcaattgcag aagcctcacc
     7261 gattccgctt attttgtata atgttccttc tagaacaggc atgtcgattc caatccatgt
     7321 attagtaaat ttagcagaac atcctaatat cattggtttg aaagaagcct caggagatat
     7381 ggcttatgtg atggatgccg ctcggttgat tggagaagaa ttcttccttt acagtggaaa
     7441 tgatgatttg atcctaccag taatgagtgt aggaggaagc ggtgtaataa gtgtatgggc
     7501 gaatatccaa cctaaaatag tccatgaatt agtaaaagat acgcaggacg gaagatggca
     7561 gcaagcaaaa gaaaagcaat taaatgcact tgaactgatc catgccttgt tcagtgagac
     7621 caatcctatt cctgtcaaag cagccatgtc attattagac ttaccttccg gacctctacg
     7681 cctgccttta gtttctcttt caaaagagaa aaagaaacaa ttagctcagc ttttgttaaa
     7741 agaaaggacg gttgaaaaat gaaaatcgga ctgattggca gtggacagat gggaaataga
     7801 gtcgaagaag ttgcacaaga aagaggagat acggtccttc ttttacggac ggcacctaaa
     7861 gaagcaacta cgcttgcttt tacggaactg ccagaactgc ttattgattt ttctcatcca
     7921 gataatttag agaaaatcct ttcgtatagc ttatcatatc aacttccgtt agtcattggc
     7981 acgacaggtt atacacaatc acagttccaa gaaataaaag aacatgccaa acatgtacct
     8041 gtgatgtata gtgctaattt ttcgttcggc atcatggtga tgaatcaact aatcaagcaa
     8101 gcagctgcaa tgttgcaagg ctggcagatc gaactgattg aaaaacatca tagtcgtaaa
     8161 aaagatgcac catctggtac tgcaaatatg ctgcttcaaa caatccaaga agtgcaaaag
     8221 ctgcagcccg tatacaactg gcaagggaaa aaaagagaag aaaaccaaat tggtgtacac
     8281 agtattcgtg caggttcttt acctggtgaa catgatgtat tgtttgctgc tactgatgaa
     8341 atatttacga tcaaacatga atctttttct aatcgaatct ttgctgcagg cgcagtagaa
     8401 gcagcggact ggttgaaaga tcagtcacca ggttattaca aattagaaga tttattaatg
     8461 gacaaagggg tgtaaaaaac gtggaagctc aagaaatcat ccgctacatt caaacggcat
     8521 ctaaaaagac gcctgtgaaa gtctatctga atgtaaccga gccaatcgaa tttaaagaaa
     8581 gtaaagtttt tggtgaagga agcagcttcg ttgtttttgg tgactatgag acgattgctc
     8641 cggttttaga agctgaatca gaaaaaatca ttgaaatcga aatcgaaact gctgcaagat
     8701 acagcgcagt tcctttgcta gatattaaaa aaattaatgc tcgtatcgaa ccaggtgcta
     8761 ttatcagaga tcaagtgtca atcggcaaca atgccgtgat catgatggga gcgattatca
     8821 atattggtgc agtaatcggt gaaaacacga tgattgatat gggtgctgtc ttaggtggac
     8881 gagcgacagt gggcaaaaac tgccatattg gtgcaggagc tgtcttagca ggtgtgatcg
     8941 aaccagcatc ggccaaaccg gttatcgtag aagacggcgt actggtaggt gcgaatgcag
     9001 tgattgttga aggtgtccat atcggaaaag atgcagtcgt ggcagcagga gcagtggttt
     9061 tagaagatgt ggcagcagaa actgttgtcg gtggaatacc tgcacgtgta ttaaaaataa
     9121 gtgatgatca gacaaaagaa aatacagcat tgattgctgc gttacgcgaa ttatagagga
     9181 gatggagaaa aatgcgcgaa atagatacct gtattgtggg ggcaaccgga ttagtcggcc
     9241 aaacgatgct caaagtgtta gaagaatatg attttccagt aggacgattg aaattattag
     9301 cttcaaaacg ttcagccggt aaagtttgtg tattcaagaa aaagaaacac actgtacagg
     9361 aattgacaga aacttcattt gaaggatatg atttagcgct attttctgca ggtgcttctg
     9421 tatccaaaga gtttgcgcca atcgcacgaa gtcagggact atttgtcata gataattcct
     9481 cagcatggcg ggaagattcg gatattccat taatcgttcc agaggtcaat ctggaagact
     9541 atacattgaa tcggctgatt gcaaatccaa attgttcaac cattcaagcg gtacttccgc
     9601 ttaaagcttt acaagaagcc tttggtatcc agcgagtcaa ttattcgacc tatcaagcag
     9661 tttctggttc cgggcaaaaa ggcattgaag atcttcatcg tacgcaaaat gacgaggaac
     9721 cagttttgta tccttataat attagccaaa cggtgattcc ggaaatcgat cagcctttgg
     9781 aaaatgggta tacaaaagaa gaacagaaaa tgataaatga gaaccgtaag attctgcatc
     9841 agcctgcttt gccagtatca gcaacctgcg tacgtgtgcc aatcgaaaat ggacatggag
     9901 tctctgtggc agttcaactg caaaaagagt ttacgacgga agaaattaga gagtgtctca
     9961 gccagtttcc agggattcaa ttagaagatg atctagcagc acataaatat ccgacgagca
    10021 ttcttgctag aggaacagat atggtttatg ttgggaggat cagaaaagac acttctttag
    10081 agaacggatt gttgttctat acgactgccg ataacatacg caaaggagcc gctgcgaatg
    10141 ccgtacagat tgctgcagct ttaatgcaga aaatagcgga ggtggcaaga tgagtaatac
    10201 gctgaaagta gcgaaattcg gcggaacatc gatgtctcat gaagagcaat tcaaaaaagt
    10261 ccgtacaatt gttctttcag atcccaatcg ccaagtgatc gttgtttctg ctttaggcaa
    10321 acgtacgtca gatgatgaca aagtaacaga cttactttat ttgatttatg cttaccttca
    10381 gcatcatgtt gattggacac ccctttggaa aaggatttgt gatcgtttca ttcaagtaag
    10441 agatgttctt gccctgcagt tacctattga agatgaacta gcacgcatac agaaacaact
    10501 ggaagacgaa aagataactg aagattattt agtaagtaga ggtgaatatc tgactgctca
    10561 actgatggct gagtatcttg gttaccagtt tattgacgca aaagacctga ttttctttga
    10621 ctatgatggg aaaatcgatc aggaaaaaac agcacaggaa atcacaaaag catttaaaag
    10681 atatccgaaa atggttgttc cagggtttta cggggcgaac cctgcaggaa aagaaaaatt
    10741 attgggccgt gggggaagcg acattaccgg cgcgatactg gcgaagatgt tgcaagcgga
    10801 aagttatgag aattggacgg atgtttcagg aatcatgatg gctgatccgc gaatcatcga
    10861 tcatcctaaa atcatcgagg aaatctcttt tagagaactg agagagatgg cttatatggg
    10921 ggctaacgtt cttcatgaag cagctgtttt cccagttcaa gaggctgata tccccatcca
    10981 aataaaaaat accaatgatc ctttcgctca agggacaaaa atatcgaatc acgaaataga
    11041 aaaggaaaat ggactgacag gaatagctgg acgcaaggat tttctttcca tcactttatt
    11101 caaacgtcat atgtccgatg aaatcgggtt tatctggaaa gcaatgagca tttttgctaa
    11161 acatgagata tcaatcgaac atattccttc agggatcgac aatatcggag tgatcgtctc
    11221 agcagaagcg attgccgata agttatttct catcacgaaa gaattaaaag aaacacttgg
    11281 cgtggaagaa atcgtcgtga tcgaagactt agctttgatc tctgtcgttg ggggtccgca
    11341 taaagaattg attggattat ctgggaaagt gttatcgata ttgaacaaat tagaaattcg
    11401 cacatcgatc ttatcacaag gagcacagga gttgaatctg atcatcggtg taccgaataa
    11461 tcaatatgaa acagtagtga agggtatcta tgaagggatg gtgaatacgg atgctgaaag
    11521 aatatcgaat ggcactccat caaattcctg aaatcgggtt tcatgaattc aagacaaaaa
    11581 aatatttata tgaacaagta aaaaacagcg aggccgttat ccatgaaatc ggcgaaacag
    11641 gactactcct ttattttgat aatcagcaag aagaaacgat tgcttttcga acagatatcg
    11701 atgcactgcc agtcaaagaa gaaacgaatc tctcttttgc ttctaagcat gaaggttata
    11761 tgcatgcatg tggtcatgac ggacatatgg cgatgctttt agggttgact gactttataa
    11821 ctaaacacat tgaggatctt atttataatg tagtactgat ctatcagcca tcagaagaaa
    11881 tttccggtgg cgcacaaagc gttattcagt caggattgtt ggataaatat gaagtacaag
    11941 caatatttgg ctttcatcta tggcctggac tagctaaggg agaagttttc tctcgaccag
    12001 gacctttgat ggcacaaagc agtgaaacag acattatcat taaaggccag tctgcacata
    12061 ttgcttctag tgaaaaagga atcgatagtc tggaggcagc tgtacgattt ttgaagaatg
    12121 tttatgattt tgaccggcaa ttaccggcag agtggaatca tctaatgaaa tttggccaaa
    12181 tccaaggtgg aacgatccga aatgttttag ctggagaagt tattgtatcc ggaagtatcc
    12241 gttcttacag ttcagatatg caaaattatt tgaagagggg attagaccat ttagcagaac
    12301 agtttcactc tacagctact atttcttttc gctataatga cggctatcca gctgtaatca
    12361 accatagagg cttatatgca gcactgttag attcaaacaa actacatgaa ttagatgctc
    12421 cagttcttca agccgaagat tttggcatat atacgcaaca atatccatgt gtatttttct
    12481 ttttaggtgt cggtgatacc cctgctttac atgatccgac gttcgatttt gatatggatg
    12541 ttttagaaaa tggtgtagaa tggtacaaaa cgattctttt tacagaaaat cttcttgtaa
    12601 aaatcgatag cagttcaaaa gaggagcgag taaataatga tgaatttatc caatcgattt
    12661 agtcctaggc tttctagaat agaagtatca aaaatacgac aattcgatca gcaaatatcg
    12721 tcgataccag atgtgatcaa actcaccctg ggagaaccgg attttccaac tcctgaacat
    12781 gtcaagcaag caggaatagc agcgattgaa gaagactttt ctcactatac cggaatgaga
    12841 ggattagagg aactgcggga agcggcttgt atatttcagc aacagcgtta tggattaact
    12901 tatgatccgc aaacggaagt tttgacgaca gttggtgcaa cggaagcgat tgcctctgcg
    12961 ttgttatctg ttttggaaga aggagacaag gttcttattc cagcgcctgc ttattcagga
    13021 tatcagccat tagtggaact agctggtgct gaattgatcc cgatagatac ttctgacaca
    13081 gggtttgtct gtcagccgga acaatttgaa cgagcatttg aacaatatgg atcagctgtc
    13141 aaagcagtca ttttaaacta tcctaacaat cctactggga cgacattgtc tgcaaaacaa
    13201 ttgaaagcaa tcgctgaggt tttaaaaaaa tatccggtat ttgttataag tgatgaagta
    13261 tatgctgaat tgacttatag tggaacgcat atgtccatag ctacttatct tccagaacaa
    13321 acaatcgtga taagcgggtt atccaagtca catgcgatga ctggttggcg agtgggcttt
    13381 atttttgctc aaaaagccct tattgacgaa ctaattaaag tccatcaata tctggtgact
    13441 gccgctacaa cgatgtcgca aaaagctgcg gctgaagcgc taataaatgg ggtgaaagat
    13501 agcgagaata tgaaagagca atatcaaaca cgaagagact atctggtcca gcaattggcg
    13561 cctttaggat ttgaagtgac ccagccaaac ggtgcatttt acttgttttg caaactccca
    13621 gctgccattc aaactgactc ttggcagttt tgtgtagaat tagcggaaca ggcaaaagtt
    13681 gcgtgtatcc caggaattgc atttggccca gaaggagaag gttatatccg gatttcttat
    13741 gctagcagca tggaaaaatt acatgaggcc tgcaaacgga tcaaagactt tttaacagaa
    13801 cagtgattca tagattttat caaaaaaaca atcgttaatt ttgcggtata ttctgcaagg
    13861 agacgattgt tttttaaatt tagttcaaat gaacgcgttt cttttgattc ataactaatg
    13921 taatgttaag tttaaattgt ttagaatgat tttaaaagaa tattcaagga ggtttcatca
    13981 atggaaaaaa tcaaagttgt cattgtaggt gcatctcatg gagggcatca atcgatcttg
    14041 gaactattga cacgatacgg tgaaaatgta gatatcacgc tatttgaagc aggagactat
    14101 atttccttca tgtcatgtgg tatggagctg tatttagaag acaaggtaac agatgtaaat
    14161 gatgtacgta atttcagacc agaaaacttt ccgcaatcca atgttcatat tttaaataat
    14221 cacgaagtaa aaacgatcga tgccgataaa aaaacagtaa cggttactag cgcatcagat
    14281 aacgaaacaa aagaatatcc ttatgacaaa ttgattttga gttctggtgt caaaccaaac
    14341 aatctgccag taccaggagc agatctagaa aatgtctact tgatgcgtgg atacaattgg
    14401 gcaaccaaaa tcaaagaaaa attaaatgat ccggctatta aaaaaatcgc tgtcgtaggt
    14461 gcgggttaca ttgggatcga agcagcagaa gcaagccgaa aagctgggaa agaagtcgta
    14521 ttgcttgatg tgatcgatag acctttaggc acttatttag atgctgagat gacagatatt
    14581 ttagaacaac acctaaatga aaacggtatt gaagttttga caaatgcaaa aatcgaagct
    14641 tttactggta acggaaaagt tgaggcaatc aaaacaagtg aaaaagaaat cccagcagat
    14701 ctagtcattc aagctgccgg tgtgaaggca aatacagaat ggttaaaagg gatcgtcgac
    14761 ttagatgaac gtggctggat ccaaacaaat gaatacttgc aaacgaatct tccagatgtg
    14821 tatgcagtag gagatgctac acttgcttat tctatcccag cacgcaaaaa aatgccgatc
    14881 gctttagcga ctgttgcacg tagagaagca cgttatgtag taaaacatct ttttgaagaa
    14941 gtaccaaaca aaccgttcgg cggagtcgta ggttcctctg cattaagtgt ctttgactat
    15001 cattttgcag caagcggatt gaatagcttt acagcagcaa aagcaggagt agatgtacga
    15061 gtgtcttatt atgaagatac gttacgacca aaatatgtac cagaagaaca aggaaatcca
    15121 aaagtgtcca tccaattatt ctcggatcca atgacccatc aattgctagg aggagcagta
    15181 ttatctacct atgatgttac aggtcaagga aatgtattgg cactagcgat ccaaaacaaa
    15241 ctgactttag aagaactagc agaagctgac ttcttcttcc agccaggctt tgaccgacaa
    15301 tggagcatgt tgaatctagc cgctcaacaa gcgttaggag aagaaccatt tgtagaataa
    15361 gaaaacgaaa tatttgaaaa gaggttgtga aaaagctgcc ttgcatcaag taataagaac
    15421 agccaagtaa aaacagcttc ttatgttttt aacttggctg gacttattac cgcagatgca
    15481 agcttttgaa caccgtttat tttcaaaaaa gggactgtga cacgatttgt gtaccgaccc
    15541 ccaaaagtta gaccaaaaaa tctaactttt ggaggtcggt attttttatg gttaaatata
    15601 cttttgaact taaattaaag atcgttcatg attatttgga tggcaaaggc gattggaccg
    15661 taaaaatcca gatcaagaga ttgaagcgga aatgcttaaa attcgggaga agcacaagga
    15721 ttatggctgt ttacggatga ccaatgaact aagaaaccgc ggtttctcta tcaataaaaa
    15781 gaaagttcag cgcttgatca agaagctagg aataaaagta acggcataca cgcgtaaatc
    15841 acgtcgctac aattcttatc gaggaaaagt
//
LOCUS       DAFEEZ010000067        15383 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000067
VERSION     DAFEEZ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15383
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.070"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            348..857
                     /locus_tag="LP245_002279"
     CDS             348..857
                     /locus_tag="LP245_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1520169.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            950..2112
                     /locus_tag="LP245_002280"
     CDS             join(950..1226,1226..2112)
                     /locus_tag="LP245_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL1520170.1"
                     /translation="MSRRQRRTYSKEFKQQIVDLYLAGKPRAEIIREYELTPSSFDKW
                     MKQAQSTGSFKERDNLTPEQAELIALRKKNKQLEMENDILKQAALIFGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2392..3372
                     /locus_tag="LP245_002281"
     CDS             2392..3372
                     /locus_tag="LP245_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1520171.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3494..4912
                     /locus_tag="LP245_002282"
     CDS             3494..4912
                     /locus_tag="LP245_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HBL1520172.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4983..6452
                     /locus_tag="LP245_002283"
     CDS             4983..6452
                     /locus_tag="LP245_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1520173.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6462..6929
                     /locus_tag="LP245_002284"
     CDS             6462..6929
                     /locus_tag="LP245_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1520174.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6965..7837
                     /locus_tag="LP245_002285"
     CDS             6965..7837
                     /locus_tag="LP245_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL1520175.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7919..10453
                     /locus_tag="LP245_002286"
     CDS             7919..10453
                     /locus_tag="LP245_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL1520176.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10609..11382
                     /locus_tag="LP245_002287"
     CDS             10609..11382
                     /locus_tag="LP245_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1520177.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11375..12166
                     /locus_tag="LP245_002288"
     CDS             11375..12166
                     /locus_tag="LP245_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL1520178.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12176..12667
                     /locus_tag="LP245_002289"
     CDS             12176..12667
                     /locus_tag="LP245_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1520179.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12685..13095
                     /locus_tag="LP245_002290"
     CDS             12685..13095
                     /locus_tag="LP245_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1520180.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13099..14499
                     /locus_tag="LP245_002291"
     CDS             13099..14499
                     /locus_tag="LP245_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HBL1520181.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14522..14896
                     /locus_tag="LP245_002292"
     CDS             14522..14896
                     /locus_tag="LP245_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL1520182.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5340 a         2168 c         3068 g         4807 t
ORIGIN      
        1 ataagtcatt tatgttcact ctccttgtat gctttagcgg gtattacaat ttgagtgtaa
       61 cataaatggt ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga
      121 aatgaattat aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct
      181 atcataagtg gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt
      241 agcggataat cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat
      301 agccctaaac aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa
      361 tagaaagagg tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca
      421 tcaaagtaaa taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc
      481 taaaactcag tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta
      541 gtattacgga attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc
      601 ccactttaga gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta
      661 aacttgtatc gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg
      721 aagagcttta tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa
      781 ccattaaaca gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga
      841 caagaaagga agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca
      901 gaaaaaataa ggtgtgtaaa ataaatgaaa acacactgga ggatttttca tgtcaagacg
      961 tcaacgaaga acctattcaa aagaattcaa acaacaaatc gtcgatctct atctcgctgg
     1021 taagcctcgc gcagaaatta ttcgagagta tgagcttacg ccttcttctt tcgataaatg
     1081 gatgaagcaa gcacaatcaa cgggctcatt caaagaaaga gacaacttaa caccagaaca
     1141 agcagaattg atcgcactaa gaaagaaaaa taagcaactc gaaatggaga atgatatttt
     1201 aaagcaagcg gcgctgatat tcggacgaaa agacaagtaa ttgataccaa taagcacaaa
     1261 tactcaatat cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa
     1321 gccaaaccag ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc
     1381 aatcgaaaag cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa
     1441 gtgagtcaac gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca
     1501 ttggctcatt tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta
     1561 gacggaacct tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt
     1621 cgtgttggga agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc
     1681 atcggctatt catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag
     1741 attccgtact cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat
     1801 aaccagacga ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa
     1861 ggctgcccct atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc
     1921 gttcatcaat accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc
     1981 cattggtgga ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt
     2041 cgacagcaga gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc
     2101 gaggcacctt aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg
     2161 ttgtcaaggg cagtcggaac accagcagca agcttacgca ataccttata atttttgtca
     2221 aaaaaagtgt tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg
     2281 atattatata tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat
     2341 gtcgaatagt cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa
     2401 attggaatta gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta
     2461 ttgaatgatc gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa
     2521 aaattagaat actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc
     2581 gtaggtttga tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc
     2641 gagttcgagc tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca
     2701 acaaaagaaa aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta
     2761 ggaacgcaca ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt
     2821 gatagaagtc ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa
     2881 ttagctactc aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat
     2941 agtaagataa agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa
     3001 ttcatgctgg aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat
     3061 gaaataatta agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat
     3121 gatttattgg cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa
     3181 gaggttaaag tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta
     3241 tcaactattc aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat
     3301 atgattaagg gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa
     3361 aatacagcat aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga
     3421 aacgggttga catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca
     3481 ctggaggaag aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca
     3541 acctaaggat gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat
     3601 ttatcatcaa cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt
     3661 agcaactacg aaagattttg ttcattttga agactttggg gaatctcttt taagagggga
     3721 tgacaatgag agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt
     3781 tcacgcattt tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt
     3841 gttgcttcat gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga
     3901 gttagaacca caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga
     3961 tgatgaaaaa gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct
     4021 acaaaccgga cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg
     4081 tgatttttgg gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg
     4141 tgactggtgg tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat
     4201 gagtcaaagt ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc
     4261 ttattatgca ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc
     4321 aacaaaagat caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca
     4381 tgaagtctat caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa
     4441 tgcattcata aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga
     4501 agaagtaacg cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt
     4561 tgatgagaat cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc
     4621 ttacgaatat cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta
     4681 cccttggttt caatatatgg ataaaggact tattagacct atatctttaa agcctaacca
     4741 atcttataaa ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat
     4801 cgctcttaac gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa
     4861 tggatcaatg actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc
     4921 aatcatgtgg caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat
     4981 gaatggacta caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata
     5041 tctcaagcgc tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag
     5101 cgaatatgga aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac
     5161 agttacaagt aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat
     5221 tgacaggagc taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag
     5281 gaaatagact tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag
     5341 cttttattgg ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt
     5401 ttggaatgga tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc
     5461 tgggtattat tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa
     5521 aacgttttgg cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag
     5581 gactagccaa tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat
     5641 ttggattaag cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt
     5701 cttggttttt agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt
     5761 acattttagt cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg
     5821 gtccattggg gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga
     5881 agatgggtgc ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag
     5941 gaacacaaca tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt
     6001 atatccaacc tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt
     6061 atttactctt taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa
     6121 cactggtagg tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc
     6181 cttttgtttg ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg
     6241 taaaagccat tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc
     6301 ttccttatat atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt
     6361 atgataaata taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg
     6421 actcaaaaaa attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa
     6481 aaaatgaaat aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa
     6541 gtgatccagt cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg
     6601 aaacgattgt atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct
     6661 taggaataaa aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg
     6721 agctaaatgg tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg
     6781 atattcttat gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca
     6841 ttgttgtttt tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac
     6901 aaggacaaga attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa
     6961 atgtatggtt tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga
     7021 taaagatttg aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat
     7081 gaatttagtt ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg
     7141 atcgttcggt cctattgata ttcattgtga atctaaaacg tatggcttca ttacatcaac
     7201 gccaaaactt gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat
     7261 tccaactgct tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa
     7321 tggcagaggc ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc
     7381 tatccaaaac ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt
     7441 aaaacgacac aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga
     7501 gggcttagct gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac
     7561 tgaaaatgac gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac
     7621 aacattgatg ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca
     7681 cttaaaaaag aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc
     7741 cgatgttgac aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg
     7801 tttagcttta gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac
     7861 tatttgtttg gttgatgcga tctttttttt caattagtaa ttgaagggac gcctaaaagt
     7921 gaaaaaaaaa atgaaagatg aagtattaga gtatatcaaa aataatttaa agtattacga
     7981 tttttctgct caagatattg caatgaaatt ttgtattaaa agaaatgtcg cttcccacta
     8041 tttgaatcag ttattttcag atggaaaatt actaaagaat gattctgtta gaccagtaat
     8101 gttcaagtat aatcaacaaa agccaaaaga ctgcttttct aagtttattg gagcagacat
     8161 atctttgaaa tccactatag ataaatgcaa agctactgta atgtatcccc ctaatggcct
     8221 cccattaata ataaaaggaa acagtggcgt tggaaaaagt tttttagcaa gtttgatcta
     8281 tcagtatgct cttgatagaa aagtaattca taatgacgca aaatttgttg ttgtgaattg
     8341 tgcagattat gcaaataatc cagagctatt gtcagcagtt ttatttggat ataaaaaagg
     8401 agcctttact ggggctgaaa aagatactgc agggatgcta tcttctgcta atggaggata
     8461 ccttttttta gatgaggttc acaatctaag tgcagaaaac caagagaaat tgtttcttct
     8521 tatggattct caaaagtatc gtaaacttgg tgaaagtgtg caatgggagt atgcaaatgt
     8581 tcgccttatc ttagccacaa cagaagataa aaatacctct ttgttagcaa cttttagaag
     8641 acgcatccca gctgaaatca ctctgccaga ttacaataat agaagtacat ctgaaaaaat
     8701 tcaattatta tttgaatttc ttaaagatga agcaattaca attgattcaa aaatattttg
     8761 ttcgattgaa ctttttactg atcttttatc gaaaacattt gaaggaaatg ttggagaatt
     8821 gaggaatgaa atcaagcttc tttgtgcaga aggttattta ggaaataaga gaaagtcttc
     8881 aatttattta ggggacaaac tagacagcgg tttttggata gatccagaaa ttagtataga
     8941 tttaaaaaaa atgtttctta aatcactttc tgaaattgat ttgattgaac tttttcaaaa
     9001 tcacatttca attgaagaaa gcatgagtca attaagagat agaatactta aagagtgtgc
     9061 aggttcttct gagtataatt atttagaaag tgacgaattt atagcattaa gaaactatgt
     9121 tgttaataaa atatcaccaa ttattgattc gacaggtcta tgtttattag atgaattctt
     9181 ggcggatatc agtctattta taatgtttat tgatgtaatt gaagaaacat caagaaattt
     9241 tttgctgtct aagttcagaa aatttcgtat gaaaaatgat aaacaaaaat tattggcaaa
     9301 tgagatttgg agtagtttag aagtcgaaga aagtaaacaa gaacttttgt tgaaatggat
     9361 actttttctt gtaaagaagt tctatgtgaa aataccagaa acccattgtc tgatagttat
     9421 gcacggtaaa ataacagctt ctgcgatcgc aagggaaaca aataagttgc tgaatacata
     9481 tgtttatgag gctttcgata tgccaattga aggtgagact agtgacttaa ttaacctaat
     9541 caacaatttt tgtaaaagta tagatacgac gaatggactc attctgctag ttgatatggg
     9601 atcattggaa caaatgtatg aaaaaattga atccaatgta ataggtgatt tggtaatttt
     9661 aaacaatgtt tctacagctt tagcgattga atgtgggatt caagtttgcc aaaaaaagcc
     9721 aattagtcat ttttaccaga tggattttga ttcgtttcaa gttaaagttc agtattataa
     9781 aggattatca caaaagaaaa atgtaatagt atcttgtctc tctggtgagg ggatttctga
     9841 aaaagttaag gatattttaa aacggtatct cgataatcaa gtggagattt tgatttttga
     9901 ttttaacgca ttaaagaaaa tagcaaagga aaaagatact atgattttta agaatacaat
     9961 ttgtgttctt tcaaccactg aattttacat tcaaggaatc gattgtttaa atttagaaaa
    10021 tctaattaat gggaatcaaa ccttagaaaa attaaataag tatatggact cggatagctg
    10081 tgagttctgc ttaaatgaat tagttaaact ctttactatt gaaggcgcta gtactaagct
    10141 tcgcttttta gattccaaaa aagtattcaa tgagatagaa aaagtactat atttgtatga
    10201 aaaatattac gatgtcaaaa tcccaagttt tctgagaatt aatctatttc tacatctttc
    10261 tggaatgatt gaacgaatta tgattggtga tggaataaca aatgaacatt tgaaagaggg
    10321 agcgcaacta tttgatactt ttttaaatgt atcaaaagat tttttttcag aaatcaaaga
    10381 tatttactgt attgaaatac ccaaaggaga gtatgagtta atctatacaa tttttgagca
    10441 gactattttc taaatagcat actagcgtct aaaaaaatga aagggtgtcc aaagtatatt
    10501 tagacgctca tttaattaat atttactgta ttttcccgct ttattggata atgttagttg
    10561 gcacagtaat tgcttatata aaagtataag aagaaaggag agaacaaaat ggcgttttgg
    10621 caaacatttt tagttgtgtt gtatggattt ttcattaact gggataagga agggcccaaa
    10681 atcggaacct cccaacctgt cgttgcaggt ttcttgaccg gacttattat gggagatatt
    10741 caaactggac tttatatcgg tgggactttg caattaatga cactaggtat tactagtttt
    10801 ggtggtgcat cagtaccgga ttatcaaaca gcagcattga tcggtactta tttagcaatc
    10861 tcaactaacc aggatgcttc tataggaata actttagcaa taccggtagc aatgttaatt
    10921 gtacaactag atgttctaaa gtggtcaaca aacatttttt ttcaacaaaa ggcagaaaaa
    10981 ttcgcacaaa aagaagatta tcaaaaatta gagtggatgc aatatttggc atcaattaat
    11041 acaagctttg tatctggaat tcctgttttg ttaactgtga tattaggccc aacgttagtg
    11101 ggaagtgcaa tcaattatat tcctgaatgg gttaccggtg gtttaaaggt agcaggggga
    11161 ctattacctg ctgttgggat aggaatgcta cttaaatatt tacctacaaa agattacttt
    11221 gcctatttgt tagttggttt cgttttggca gtttatttcc aaataccaat tttagggatt
    11281 tcgttacttg gcgctgcaat cgcactaatc gtatataaaa atagatcaaa taatactcaa
    11341 gtagcaccag ctgcaacagg aggttttgac gaagatgaat aagaaactga caaaaatcga
    11401 caaacaagta attttccggt ggattctcaa tggtgcaact tcattaaatt atgaaaaaat
    11461 ggaagggttg ggttatgcgt attctatgct tccttttatc aaggacacat ataaagatga
    11521 tcctgaagga atgaaacaat ccgttttagc tcacctacaa ttttttaaca ctacgccgta
    11581 tacagcgcct tacattattg gtatgaatgt tggaattgaa aaagaagaaa aaaataagtc
    11641 tttggaagca gtaagtgctc tgaaaacagg tctaatgggt cctttagcgg gaattggaga
    11701 tagtgtattt gtagttattc catggactat ttttggagca attgcagcta atatggcatt
    11761 ggaaggtagt tttgttggaa ttattttgtg gatactggca tcaattttat taaggattac
    11821 tgcttatcct ttataccttg ctgggaaaga atcgggtgcg agcctactaa ctcaaattga
    11881 aacaaaatta aagtctatta ctgatgcagt atcaatttta gggttaatgg tggtcggtgc
    11941 actcattgcc acagttgtaa aagtgaatgt tggctttgaa tttaaacaag gcgacttaac
    12001 aatgaccgga aatgaaatct ttgatcaagt tatgcctggt ttattacctg catgtgtagt
    12061 agcaattgtg tattatttgt taggacgaaa ggttaaacca gtttatgtaa ttctattaat
    12121 cttagtagtt tctattgcgt taagagcgtt aaatattttg aagtaggtgt tgaatatgga
    12181 tgaaaaaatg aaaggtatta tacatgttcg tattgatgat cgaatgattc atggacaagt
    12241 agcaacacaa tggacaaatc aattgagtgc taacagaatt atggttatta ataatgaagt
    12301 agccaatgat gacgtaaaaa aagctgtagt tcgcctcgct gcaccaccta atgttagaac
    12361 ttcaataatt acaagggaag tagcagttaa aaatattctt tctggtaaat atgaaggaca
    12421 aaaagttctt attgttgcag tttctccaat cgatgttaaa tttttgattg ataacggttt
    12481 accaataaca agtgtaaacg taggaaattt atcaagaagg aatggaacag aacgcatccg
    12541 tccgacgata aatattactg aagaagagag agaggctttt aaagaactaa ttagtgatgg
    12601 agttgaagtg acagtgatac aaactcctag agattcaaaa gaatttttaa aggattttat
    12661 ttattaagaa cagaggatga gtggatggag tttataatta catctcatgg aaatattgcc
    12721 attggatttg tagatacatt aaaaatgttt tttggcgata atttaaattg tcatgtggta
    12781 acacttggag atgcaggcat tgaagaattc cgtgaaaaca ttgaaaaaat agtttctcaa
    12841 gtaaaaaatc aagaagttat ggtatttgct gacttgattg gtggaacacc tttcaacgaa
    12901 tttgctaaaa gaagtgaagt atttcaaaat gggtttcaac ttcttggtgg catgaattta
    12961 ggaattttga ttgaggctgt caatttgaga ttacaaggaa aaaaaagcga tgatatcatc
    13021 gaaaatctaa gaaatatgaa tacaattgcg tgtcttgcag atatgcaaag acatactaac
    13081 gaagaggatg agtgataaat gcaaaaaatt ttttacaagc ctaaagattt ttggtttggg
    13141 gattgcatgc ctttttataa agatggaact ttttatctat ttcatcaacg agatacgaga
    13201 aatcctaaac ctttaactga tccttttggg tggtcactag ttacaaccac tgattttgtg
    13261 aaatttgaag aatacgggga agtaattcat cgtggtggca acgatgacat tgatcaatac
    13321 atttacgctg gaagtattgt ccaaggaatc aatgagtatt tagctttgta tactggacat
    13381 aatcgcaaag ctaagttgga tggaaaaact tcagaagtgt taatgattgc aagttctaaa
    13441 gatttaattc attggaaaaa ggatggcgaa gcagcaaaac ttgttcctca agaaggatat
    13501 gataagaatg attggcgcga tccttttgca atttttgatc aagatcatgg aaaatacgtt
    13561 ttgatactag gagctagaaa accagcaagt aagaaaaagc cgacggggag attggtctat
    13621 tttgaatccg aagatttaaa agattggaat ttcaaaggag actactgggc taataatgaa
    13681 tttaacatga ttgaaatgcc tgatatattt gaaattgatg gaacgtggta tttacttttt
    13741 tcagagtatt gtgaagataa aaagactaaa tatcgagtcg gagcaggatt attttcagat
    13801 tggaaatcac cagtagacga agctttcgac ggaaaagcct attatgcagc aagaacagtc
    13861 ggaactaatg aaactggccg ttttctaact ggctgggtgg caacaaaaga aggggagaac
    13921 gatcaaaata actgggattg gggcggtgca cttgttccac atcaaattat tcaaaagaca
    13981 gacaaaactc ttggtgttaa actgcctgaa aaaataattg agaattttaa agaaatcact
    14041 ccattttcaa gttttaagtt agagaaagaa tttggaaaaa aagaaagagt aattgttcct
    14101 aaaatcgaag attattttct atttgaaaca actttgacta ttacatcgtt aacaaaggag
    14161 tttgctttaa aattatttgt agatagtgat actcaagaag gatacgaatt tcgtatttca
    14221 ttgattaata atcagcttac tttcggaaaa actccgaact atccttggcc tcaaatgttt
    14281 gataaggggc tgcaacgacc actatttttg gaaataggca aagaatatga actaaagtta
    14341 attgttgatg atacgatagc tgttttatat attgataatg ttgctttaag tactagaatg
    14401 tatgataaag tcggaacagc attaagtatg actgttacgg agggagcaat caaggtagat
    14461 aaactagact attcaataaa ttatgaatgt ggattttaaa acaattgaag ggatgatgta
    14521 agtgaaatta aatggtttac aacatattgg aattccaaca aaagattttg gagcttcaaa
    14581 aatcttttat gaatccttag ggtttagtct gattaatgaa gaaatgaatg tgggaagtaa
    14641 agtcggcttt ttcgagttga atggaacgat aatagaaata tgggaagata aaactactga
    14701 gtgtagagga gccattgatc atctagcatt agatacggat gacatagatg aggtattcaa
    14761 ttcaattcaa gatttaggat atgaattatt agataaaaat attatggaat taccgttctg
    14821 ggaaaatgga atccgttact ttaatttcta cggaccaaat catgagatta tagagataag
    14881 ccaaatgaag aaataaatag ataacgaagt gctctaagtt ggtatgaacg aaaagtactt
    14941 cattttttgg tatcagcatt tcaatagttt aatgagaatt tactatttca aattaattca
    15001 aagtgacagt attttttact tatttggttt caaattttgt aatccttcct atttattgga
    15061 atacactcca cattttgtat acaagtcata tcatgtttta gcaaagctct taccaagcaa
    15121 agttataatg atgttttcca aagtttgatc tttcgatgga ggctaacaca tattttttgc
    15181 aggacagcca aaattagatg tatagaatag agtctgtgag gcgtatagac agtttattgt
    15241 ctgtatgcct ttttttattt tgaaaaattt ttagtatttt tcgaaaaatg ctcactccta
    15301 gagtaagcgc cccatagaac agtaccttac taacaaatgc acctcaagat atacttgagc
    15361 tatcaagaag tctggaggtt ttc
//
LOCUS       DAFEEZ010000068        15296 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000068
VERSION     DAFEEZ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.071"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            332..946
                     /gene="gmk"
                     /locus_tag="LP245_002293"
     CDS             332..946
                     /gene="gmk"
                     /locus_tag="LP245_002293"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBL1520183.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            951..1256
                     /locus_tag="LP245_002294"
     CDS             951..1256
                     /locus_tag="LP245_002294"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBL1520184.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            1509..3917
                     /gene="priA"
                     /locus_tag="LP245_002295"
     CDS             1509..3917
                     /gene="priA"
                     /locus_tag="LP245_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBL1520185.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            3932..4423
                     /gene="def"
                     /locus_tag="LP245_002296"
     CDS             3932..4423
                     /gene="def"
                     /locus_tag="LP245_002296"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBL1520186.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            4416..5354
                     /locus_tag="LP245_002297"
     CDS             4416..5354
                     /locus_tag="LP245_002297"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBL1520187.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            5354..6712
                     /gene="rsmB"
                     /locus_tag="LP245_002298"
     CDS             5354..6712
                     /gene="rsmB"
                     /locus_tag="LP245_002298"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBL1520188.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            6725..7465
                     /locus_tag="LP245_002299"
     CDS             6725..7465
                     /locus_tag="LP245_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBL1520189.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            7462..9531
                     /gene="pknB"
                     /locus_tag="LP245_002300"
     CDS             7462..9531
                     /gene="pknB"
                     /locus_tag="LP245_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBL1520190.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            9696..10595
                     /gene="rsgA"
                     /locus_tag="LP245_002301"
     CDS             9696..10595
                     /gene="rsgA"
                     /locus_tag="LP245_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBL1520191.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            10608..11258
                     /locus_tag="LP245_002302"
     CDS             10608..11258
                     /locus_tag="LP245_002302"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBL1520192.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            11259..11897
                     /locus_tag="LP245_002303"
     CDS             11259..11897
                     /locus_tag="LP245_002303"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBL1520193.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            12052..12906
                     /gene="mreC"
                     /locus_tag="LP245_002304"
     CDS             12052..12906
                     /gene="mreC"
                     /locus_tag="LP245_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBL1520194.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            12910..13419
                     /gene="mreD"
                     /locus_tag="LP245_002305"
     CDS             12910..13419
                     /gene="mreD"
                     /locus_tag="LP245_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBL1520195.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            13674..15248
                     /locus_tag="LP245_002306"
     CDS             13674..15248
                     /locus_tag="LP245_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL1520196.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
BASE COUNT         5127 a         2872 c         3323 g         3974 t
ORIGIN      
        1 tattaagcca aatttatgca aaaatgtgag aaactatttt cacaaaattt ttcttcatac
       61 tcgaaactaa tcggcttctt cacgacctct tatacacggc gttcaaaagc ttgcatctgc
      121 gataataacc ccaaccaaac gaaaaacatg agaagctgtt tatgtttggc tgttcttatt
      181 acttgatgca ggacagcttt tttacgacct cttggtacag ggtagctttt ttaccaattt
      241 ctagctataa ttaaagataa ccttgaaagt tgcagaaaaa aagtgcaaaa taaacgataa
      301 gtacaaaaag actagttgaa aggacgtcgt catgtcagag cgtggattat taatcgtgtt
      361 gtctggtcca tccggtgtag gaaaaggcac agtacgaaaa gcaatttttg agagtgagga
      421 taatgatttt cagtattcga tctcaatgac tacccgtaaa atgcgtgaag gggaggtcga
      481 aggcgttgat tatttcttcc gaagcaaaga agagtttgaa tcaatgatcg aagctggaga
      541 gatgctggaa tacgcagaat atgtcgggaa ttattatgga actcctttgt catatatcaa
      601 caagacattg gatgaaggaa aagatgtttt cttggagatt gaagtccaag gagcaaaaca
      661 agtcaaagaa aaagtgcccg atggtgtatt catctttttg actccgccag atttagcgga
      721 attaaaatca cggatcgtag gccgaggaac agatgcagat gaagtaatcg aagaacgaat
      781 gaaagttgca aaagaagaaa tcgaaatgat ggctctttac gactatgctg ttgtaaatga
      841 tgaagtgccg ctagcagttg aacgaatcaa aaacattatt gccagtgaac attttcgagt
      901 agatcgcgta atcggtaaat atattaaaat gttaaaggag atgtagtctt atgatgttaa
      961 aaccttcaat tgactcacta ttagatcgtg taaattcaaa atattctcta gtgattttag
     1021 caagtaaacg cgcgcatgaa ttggatgcaa gtgcacagcc tactctagat tcttttgatt
     1081 cagtaaaaag cgtcggtcaa gctttagaag aaatcgatgc aggaaatgta gtcaatgatc
     1141 cacatcctga attaaaacgt gaacgtttga agatggaaga agaggaacgt caagcacaaa
     1201 aagagcgtga acaacacgaa ttggaatcac gtatccgtga agagcaaaaa atgtaataaa
     1261 gaaaaataga gcgaacatct aaaaagaaaa gcaaacccag ctgtttcctt ttcaaacatt
     1321 cgccacttat tgtctggtag aaaaggctgt gtctgaactt tttgacacag ttcttttttt
     1381 tcttatctgc tgttaatttt ttgttaggat ttggcagaag ataagacaaa tccatcgatc
     1441 tctagtaaaa taggcaagga actttttgtc gcttgataag aaaagacaaa aaaaggagga
     1501 aacgaaccat gacattaaca gctgaagtca ttgtggacgt acctactatg cagaccgatc
     1561 agccattcac ttatttggtt ccctctgaaa tggaaacagc tttgcaagtc gggatgcgag
     1621 tagaagtccc ttttggtaat ggcaatcgtc atgtccaagg atttgttatg gctatccaaa
     1681 aatcagaaga atcagctaat ccatctttga aggcagttat tcgtttgcta gaccttgctc
     1741 cggtggtcaa tgaagaatta ctttcattag ctgattatat gaaaaaaatt acttacgcat
     1801 tcaaaatcac ttgtctacaa acgatgcttc cgagtgtgat gaaagcagaa tatgataaat
     1861 tgatctatcc tttggcagac acaccagaag ttcaggtatt gtttgatcag cgagaagtga
     1921 tttcctggaa ggaagcagaa gaagaaggca gcctttctca attgattcgc tggcgccaag
     1981 agcaattagt agatatcaaa tatgaagtcc atacacgaaa taaagtaaaa acgattcgtt
     2041 tggtccgttc tttgttaact gaaaagcaaa tcgaagaaga atgggcaaaa ttacggcaaa
     2101 atgccaagaa acaaaaagaa cttcttttgt gtttatctga actgagccaa gaagaaccaa
     2161 ttgcttattt caaaaataaa ggaatcagta ctgctgtctt gaatcaagga aaagaaaagg
     2221 gctggctgga gtttatagaa tcagaacgtt atcgcgaccc ttataaagac cgagtatttg
     2281 accaaacgac ggcattggaa ctgaatgcag aacaaaaaaa tgctgtcgaa caaatcatca
     2341 cagcaggtca gcagcaaaaa gatcaggtct ttttgctgga gggaatcact ggcagcggga
     2401 aaacagaagt atatcttcag gcaatcgctg atgttttgtc agaaaataaa acggctatta
     2461 tgttagtgcc tgaaatcgca ttgactccgc aaatggtcga gcgattcaaa ggacgcttcg
     2521 gagaatcagt tgcggtctta catagcggac tttcccaagg tgaaaaatat gatgaatggc
     2581 gcaagattga gcgggaagaa gcgcaagtag tagtaggcgc acgatctgct atttttgccc
     2641 cgctgaaaaa tatcgggctg atcattatcg atgaagaaca tgaatcaagt tacaaacaag
     2701 atgagacacc gcgttatcat gcgagagatc tagcaatttg gcgcagtaaa tatcatcatt
     2761 gcccaatagt tctaggaagc gcgacgccct ctttagaatc aagagcacga gctcaaaaag
     2821 gcgtttatca gttattgcag ttaaaccacc gagccaaagc agctgcacag cttccagcta
     2881 ttgagatcgt agatatgcgt gaagagtttc agaatcatcg gacctctact ttttctgcta
     2941 atttgcagga aaaaatacaa aatcgattag acaaaaaaga acaaactgtc ctactgctca
     3001 atcgtcgagg atattcgtct tttgtgatgt gtagggactg tggatttgtt cttccatgtc
     3061 ctaattgcga tatctctctt acactgcata tggatacacg ttcaatgcgc tgccattatt
     3121 gcggacatga agaacctatt cccaatcgct gtcctaattg tggcggcaat aaaatccgct
     3181 actatggaac aggtactcaa aaagtagaag aggaactccg agaactttat ccgcaagcta
     3241 ggattttgcg tatggatgta gataccactc gaagaaaagg ggcacacgaa cagattttac
     3301 aaaaattcgg tgcaaaagaa gcagatatat tattagggac acaaatgatt gctaaaggtt
     3361 tggactttcc agaagtgaca ttagttgggg tgttgaatgc tgatacctcc ctgaatttac
     3421 cggattttcg ttctagtgag catacattcc aattgcttac ccaagtttca ggacgagcag
     3481 ggcgagcgga aaaagcaggc gaagtcgtga tccaaacatt caatcctcaa cattacgcca
     3541 tagaattagc taaaaaacaa aattatgagc agttttatca gcaggaaatg catgtacggc
     3601 atcgtggagg ctatcctcct tattacttta ctgtgaaaat aaccgccagc catcctgaag
     3661 aacaagtagc ggcaaagaaa atctttcaga ttgccaatca gctaaaagaa gtgttaagcc
     3721 ctcaaagctt gctattaggg ccaacgccca gcatgatttt gagagtgaaa aaccgatatt
     3781 attatcaact aatcatcaaa tataaacatg aaccgaatct tcctcatgtt ttggatgaaa
     3841 ttttgaatgg aagccagaaa gaacagcgac aaggtctttt tgtggcaatt gacaacgaac
     3901 cattaaactt tatttaagaa agggccaaat tatgcgctat cctatattga tccaccctaa
     3961 tgataaatta aaaagaactg ctcagccaat cgatgtaatc acggacgaga caatcgcttt
     4021 attagacaat ttatatgaga caatgattgc gaatgacgga atagggatcg ctgctcctca
     4081 agtaggacaa aacaagagaa ttgctgtgat cgaagtagat gaaggcgaga aatttgaact
     4141 gattaaccca gaaatcatcg aagcaaaagg tgaaagcctt gacgtagaag gttgtctcag
     4201 tattccgcat gtctatggaa cggtcaagcg agcagatgaa gtgaccgtgc gttattatga
     4261 tcgagacgga gaagagatag aagtgacggc ttttggctat ttagcccgtg ccttccagca
     4321 tgaaatcgat cacttagacg gtatcttgtt cattgagaaa atgatacagc agatcccgga
     4381 agaagaactt gaagaatata tggaggaaca tcttgatgac taagctagta tttatgggca
     4441 cacctgcttt ttctgtgccg attcttgaag ggctgataga atcaggttac gagatccagg
     4501 cagtggtaac acagcccgac cgtccagttg ggcggaaacg agtaattacg ccgacaccgg
     4561 taaaagaagc ggctctgaag cacggtatcc gtgtgctgca gccagagaaa atctccggtt
     4621 cgccagaaat ggaagaaatc attgaattgg tgcctgatgt gatcgtcact gcggcatttg
     4681 gccaattctt gcctgaaaag ttattgcaag taccaaaatt aggggcaatc aatgtccatg
     4741 cttctttact tcctaaatat cggggaggtg cgcctgttca ttatgccatc atgaatgggg
     4801 agaaagaaac tggtgtaacg atcatggaaa tgatcaaaaa aatggatgca ggcggaatct
     4861 atgcgcaaga aagcatacca atcactaaac aagatgatgt agggacgatg tttgaaaagc
     4921 ttagcctttt aggaagaaag ctattgctag aaacattgcc caatattttg gatggacaaa
     4981 aaccagtacc tcaagacgag tcagaagcaa ctttttcgcc aaacatcaca cgggaacaag
     5041 aagcaatcga ttggcataaa actgcagaag aaattgacaa ccaagtacgc ggaatgcgtc
     5101 cttggccaat tgcattcacg acctatgagg gcatacgctg gaaattatta tcggttgaag
     5161 tattggcaga aactacagac aaagcacctg gtacgatcat ccggaaagac aaaaaaaatc
     5221 tatggattgc ttgcggtaaa cagaccgtct tagccatcaa tgaattacag ccagctggta
     5281 aaggaaaaca ggccgtacat gatttcctta acggaagcgg tcagcaagtt cagattggtc
     5341 agcaggtgaa ataatgaaaa aaatccctaa aaaaatgaaa aaatcagtac gatatatggc
     5401 attactgaca ttagagcgag tgaacaaggg tggcgcctac tcgaatcttt tgttgaatga
     5461 gatgatcaaa caaagcgagc taaatcaaaa agatgtgggt ttatttacag aattgatcta
     5521 tggtacgatt agccatcagc gactattgga attttacgtt gcaccattga tcgctaaagc
     5581 aaaaaaagtg gatgactggg tcaagacgct tctttatctt tctgtatacc aattagaatt
     5641 tttagataaa gtccctgcac atgctatttt aaacgaggcg gtcgaaatcg caaaagtaaa
     5701 aggaaatcct gggacaggga aatttgtaaa tggtgtcttg aggaattatc agcgtcaagg
     5761 agcaccagat ctgcaaggca ttgctgatcc tatcgaaaga ctttctgtca aaatcagcct
     5821 gcctctatgg atgacgaaac gactggtgga tcaaatcgga tacgaagaaa ctgaaaagct
     5881 cggtttatcg ctatatcagc ctagccatgc tagtgcccga gtagatacac gccgactttc
     5941 cagagatcag gccatcactg ttttgcaaga agaagagatc acagctgaaa aaagccaagt
     6001 cagtccatac ggtatagtag cgaaaaaagg gcatttagct tctagctcat tgttccacga
     6061 tggcgtcatg acgatccaag atgaaagttc gatgcttgta gcgccgtcta tgcaaatcga
     6121 gcctgaacat catgtcttag atgcctgtgc agcacccgga ggtaagacga cgcatattgc
     6181 ttctttttta gatccgtcat gcggtggaga agtggtcgct ttagatgtac acgaacacaa
     6241 agtcaaactc attgaagata atgcagcacg tctaggtgtc tcttctgctg tctacgctca
     6301 aaagatggat gctagagaag tcagtaaaca gttcgaagca gagcagtttg atcggatttt
     6361 agtagacgcg ccttgttcag gtcttgggct gcttcggcga aaaccagata ttcgttataa
     6421 aaaacagccg gatgaattag cgaatttacc aaaaatccaa ttggaaattt tagaaagctg
     6481 cgcaccaact ttaaagtctt ccggtattct gacttatagc acttgtacga tcttaaaaga
     6541 agaaaaccaa gacgttgttt ctgctttctt ggaaagacac cctgattttg agaggattga
     6601 tgttttgacc aatcctatgc tacaatcatc aatcgaagag aaaatgttga ctttgtatcc
     6661 gcatcagttt tacacagatg gatttttcat ttgttgtttg cgcaaaaagt aatgaggtga
     6721 aaaaatgcag attgaatatc aatcagatgt aggaagacga cgtaacacaa atcaagacta
     6781 tgccagtgta tttaccagcc gttcaggtct caagcttgct gtattagcag acgggatggg
     6841 tggtcatcgt gccggagaca ttgccagtca gatggcggta acgaatctag gcgaagcttg
     6901 ggaaaaacaa gaagctgttg acgatgaaaa aatcgcccaa tggttcattc aatcgattca
     6961 agaagaaaat atgctgattt atcagcgtgg acaagaacag ccggaatata acggtatggg
     7021 aacaacaatc gtagcggccg ctctgtcaga tgactggttc acgattgcca atgttgggga
     7081 tagcagagct tatttgattc gtgaagataa aatcatgcaa ttgacggagg atcattcttt
     7141 agtcaatgaa ctagtcaaat caggagaaat cagcgaagaa atggcagtga accatccaag
     7201 gaaaaatatt ttaacacgtt ctgtcggcat gcctggaaca gtcgaagtag atgtttctac
     7261 tcatctttgg caactaaaag atcgactgct gttatgttca gatggcttga cgaacatgct
     7321 gtctgaagaa gaaataggaa cgatcatcaa tcaagaaggc ccattgtctc ataaagtaac
     7381 tgagctgatt gatcgtgcca atgaagcagg cggagcggat aatatcaccg ttcttcttat
     7441 cgaatataag gaggacagtg tatgatcgag ttgggcaaaa aattaaatgg ccgttatcaa
     7501 atcactggaa atatcggtag cggtggtatg gcaaatgtat ttttggcgca cgatttaatc
     7561 ttggatcgtg atgtagcagt taaagtctta cgatttgact ttcaaaatga ccagactgcg
     7621 attcgacgat ttcagagaga agctttagca gcaacagaac tcgttcatcc aaacattgtt
     7681 agtgtttacg atgttggtga agaagacaac atgcagtatc tggtgatgga atacgtcaaa
     7741 ggaatggact tgaaacgata tatccaaaca cattatcctg ttccttatga aacagcagta
     7801 aatattatgc agcagatcct ttctgctatt tctttagctc ataaccatca aatcatccac
     7861 cgagatttga aaccccaaaa cgtactgatc gataatgaag gtgttgtaaa aatcacggat
     7921 ttcgggattg ctatcgcttt atctgaaaca tcgatcacgc agacgaatac gatgctggga
     7981 tctgttcatt atctgtcccc tgagcaggcc agaggaagta tggcaacgaa gcagtcagat
     8041 atttatgctt tagggatcat cctttatgag atgttgacgg gtagcgtacc gtttgatggt
     8101 gaatctgctg taacaattgc tttaaaacat tttcaagatg atcttccatc tataaaagca
     8161 cttgatccaa atgtgccaca agcactggaa aacgtgattt tacgggcaac ggctaaagaa
     8221 cctgcagacc gttataagtc agccgaggaa atgtctgatg atctttctac agtattatca
     8281 ccagctcgtg caaacgaaga aaaatggcag cctcatgtga tggataatga aacaaaagtt
     8341 atcacacccc ttacggaaga tgcaccaatg cctgattcat tcaaatctat gcctctgcca
     8401 aaagacaagc cagaaaacga aaccttgcca gaggaggaag aagttctgcc tgatcctaaa
     8461 aagaaaggac agaaaaaatg gtggctgatc ctattagcta ttcttgctgt tttaggaatc
     8521 ggaacagctg tattctttgc ttctggcggg cgaggagaag ttgttgttcc tgatgtttct
     8581 gatctttctg aagcttctgc tagagaaaca ctcgcaaaag cgaaattaga agtagcaaca
     8641 aaaacagaag aaattgcaga tgacaaaatc gaagaaggta atgtagtgaa gacagacccg
     8701 gcagcgggaa cgacagtcaa gcaaaaacgc gaagtcactc tgtatattag tagcggcacg
     8761 aaaaaaatca aattagatga ttacagtggt aaaagttatg aagatgccga agcaagtttg
     8821 aaagaattag ggttttctgc tgacttgatt caaaaagaag aggaattcag ttcagaggta
     8881 gaaagcggaa tgatcatttc gcaatctcca tcagaagata cagaagtcga tcctaaaaca
     8941 gacacgatta ctttcacagt cagcaaagga ccagaaacag tgactttgag tagtcatgta
     9001 ggagaaaact acgaaactgt tcgtaattgg cttgttacac aaggattcaa tatcaataat
     9061 attagtgcta cttatgacta tagcgacact gtaccatcag gttcgatcat cagtcaggat
     9121 ccagcctcgg gtgaagttgt agcagaagaa acttacatca attttgtcgt aagccaagga
     9181 acagagccta aattgaatga tatctccggc tatacaaaaa gcgaagcaca aagttattta
     9241 gctagtgtcg gtgcagaata tatcgggcat gagacttccg aatattcaaa cacggtggat
     9301 aaagataaag tgattcgtac agtaccaggg gcaggaacga caattaccaa aggaatggtt
     9361 gtgaacgtaa tttactctaa aggaccagat ccagcgtctt ctagttctga aaaagactct
     9421 tcagacagtt ctagcagctc aagtagctcc agtagcacaa gcaactcttc aaaagaagaa
     9481 tcttccagct ccacaagttc atcagctagc acctcagaaa gttcaaaata agtgctgaat
     9541 aaaatatatc agaagggaat gcgacattga tttgttgcat tctctttttt gtgtttctat
     9601 ctcttttgat caattttcaa gccatatact ttgagaagtt tgcatggaat aacacctact
     9661 ttcctcttcg tatggtaaaa taaacaaaaa cggaggtggc acttatcaaa ggacaaatca
     9721 gaaaagcaat cagcggtttt tactatgtat acgcaaacgg agagacctat caaacaagag
     9781 gaagaggaaa tttccggaat cggaaaatca cgccgcttgt cggagatcag gtgatctttg
     9841 agagtgaaaa tcaaacagac ggctatcttc tggaaatctt gccgagaaaa aatcaattag
     9901 ttcgcccacc agtcacaaat gttgatcttg gaatcattgt cacaagtatc gtagagcctg
     9961 cattttctta taatctactt gaccgctttc tagttacctt ggaatacgag tcgatcgaac
    10021 cgattatttt tttgacaaag accgacttgt cagacgaccc agaaaaaatc gaagagatca
    10081 agcaaaccta tactaaaata ggctatccgg tgattgtacc caatcatacg ggtgatacga
    10141 cagaactgat ccgttacttc ccagaacggc tatcggtctt tatgggtcag tctggagcag
    10201 gaaaatcgac gctactgaat caaatatcac cggaactgaa tttagcaaca ggagagattt
    10261 ctgatgcact tggaagagga cggcatacaa cacgtcatgt ggaactgatt cctatctatg
    10321 gcgggttagt agcagataca ccaggattta gctcgattga ctttttgaca attgaagcag
    10381 gagaactgcc gagacaattt cctgaatttg tagaagcttc tgtccattgc aaatttagag
    10441 agtgcatgca tgctaaagaa cctggctgcg aagtaaaaca tagagtagaa acaggtggta
    10501 tcgcacagac acgttacgac aattatttgc aattcttaca agaaatcgaa aaaagaaaac
    10561 caatgtatgc aaaaaaagaa ggtaaacgaa aataggagga aacaagaatg aagatagcac
    10621 catccatttt gagtgcagat tttgccaatt tacaaagaga cattgagtta gtggaaaaag
    10681 gaggcgcaga ttacatccac gtagatgtaa tggatggcca atttgtccca aatatcacat
    10741 tagggccaaa tattgttcag gcaatccgtc ctgttactaa attaccgtta gacgtccatc
    10801 tgatgatcgt tgatccagaa aactacattc cagcatttgc aaaagctgga gcagatatca
    10861 ttactgtcca cgtcgaagca actcctcata ttcatcgggc acttcaaatg acaaaaagct
    10921 taggagttaa agctggagta gttatcaatc caggaacacc agtctccatg atcaaacatg
    10981 ttttgccttt ggctgatcaa gtactagtca tgactgtcaa tcctgggttc ggcggacaaa
    11041 gctttattga agaaacagta gaaaaaatta cggaactcgc tgatctacgt agagagaaca
    11101 attggactta tgcaatcgaa gtagatggcg gaatcgttcc agaaacagca aaaatctgta
    11161 aagatgcagg ggcggatgtc ttcgttgcag gatcatatat ctatggagcc gaaaatccag
    11221 tcggacaaat cgaacgatta aaagaggcat tagactaaat gaaaatttta ttagctgctg
    11281 gaggtaatcc gcaaaactgg ccgcagtctc tgctgtccaa atacgatgcc tatgtcggga
    11341 tagaccgtgg tgcgctgtac ctgcttcaag caggctaccc agtagatctg gcagtgggcg
    11401 attttgattc attgtcgaac gaagagcaga aggaagtatt tgcaaaagcc aaagagtata
    11461 cccgttcccc tgcagaaaaa gacgatacag atacacagtt aggtatctta aaaacatttg
    11521 aacgttaccc gcaagcggaa gtcactttga ttggagctac gggcggaaga ttggatcatc
    11581 ttttagccaa tctctggtta ggtatggaac ctcgcttcaa accctttgcc catcagctta
    11641 ttatcagaga ttgtcaaaat tatttgtctt attatttgcc tggagagcat atagtaagac
    11701 agataccaga tatgaagtat ttagcttatt gctgcttgac tcccgtctcg aatcttacat
    11761 taaaaggcag caagtatgta ttggaaaata aagaagtaga atatccgaca tcttatgcaa
    11821 gtaacgaatt tctttcagat accgcagaat tttctttttc agatggtatg attgcagtta
    11881 ttcaaagcaa agattgatcc ataaacaaat aaaaaaattt gtctttcagg ctaaaaatga
    11941 cagaatctat tatttgctaa aaaaaagctt aagaggagca acttaccttt tgtttcacgg
    12001 catttagtga taaaattgaa cacaagagtc taattaattc gaggtgtctt tgtgaagaag
    12061 ttcaatccta ataaaaatat tattattacc ttggttattg ttatcatcgt ggtgacgata
    12121 ctaagtgtga ccgctgcgca gcgagcgaat gaaggaaagc ccaatttctt ccaatccatc
    12181 gttaatgaca gtgttgcaat ggttgataaa acaatctctg ccccagtacg gtgggtacga
    12241 aatggagtag attctgtcca taatcttttt tcaacttatg ccgaaaatga gcggctaaaa
    12301 gaaaaaatcg atagctatga tgacgtttca cagcaaaaca agaattacga gagagaaatc
    12361 gaagcgttga aaaaagaact tgagttgaat cagacgctga ctagttacga aaaagtaacg
    12421 gcaaatgtca ttactcgttc gcctgacagt tggcaggaca tgctgatcgt agacaagggt
    12481 tctaaagacg gtatcgaagc aaatatggca gtcatgtcgc aaaaaggatt gattggccga
    12541 gtgatcgagg tcaatacggc ttcgtctaaa atcgaattac tgtcatcctc taatgaaagc
    12601 tccaatcatt ttccagtacg ggtatcttcg gctaatggcg aagcgtttgg tttgcttaaa
    12661 aactatgatg aaaagctcca tgccttagtg gtgacccaat taactggtga tacggatatc
    12721 aaagaagggg atgttgtcca gacatccggt cttggaggga attctccagc taacttgccg
    12781 atcggtacgg ttattaaaac gaaaccagat agttatgggc tggatcggga agtttatgtg
    12841 aaaccttatg cagaaatgta tgacgtgtca gttgtgacga ttgtccaacg gctagcggag
    12901 gattagtcca tgttgaagaa agaaacaatg aagtactatc tgccaatcgt tttgttcttt
    12961 ttgatgttga tagatggtca tttaacaaga atgctagggg agtggtcgaa aggcacctat
    13021 atgtcaaatg cccactttct gatattggca ttattatgtt gcagtatggc gtttgaaaaa
    13081 cgttatttac tgattaccac gattgttctc ggggctatct atgacgctta ctatattggc
    13141 gttatcggta tctatgcagt agctctccct ttaattgtat ggttgatgta tgtaatgaaa
    13201 gacgttatcc atgtcaacat ctttactgaa tttttcagta tgatcatctt tgtcacgggt
    13261 tatgaattgt ttacgatggt ggtccagttg atttttaaat tagcagtagt aaataacacg
    13321 tattttatta caaggttttt aggacctaca ctgctgttga acatgattat atttgtatta
    13381 ttcatttttc cctttaagaa attattcagt gatgaataat ttcttttttt atttttaggt
    13441 cgaaagcgaa aaagaatcgt tgttatctta agaaatgcta gacttaacgc ggctttttca
    13501 tgatcatttt ctgaaacgaa cagttttgtc atttttaaaa gttgttttga aacatttttg
    13561 taacataact attatatcgt tgacacactg ctatggtaca atttttatat cgttaagaaa
    13621 gacttaaata tatttagata tttattaaat taagccagtc ggaggaatga agagtgaaaa
    13681 agagtttaat atcagcagta atggtatgtt caatgacctt gactgccgta gcatcaccga
    13741 tcgctgccgc ggcggacgat tttgattctc agatacaaca gcaagatcaa aagattgcag
    13801 acttgaaaaa tcaacaagca gatgcacaat cacaaatcga tgccttagaa agccaagttt
    13861 ctgaaatcaa cacacaagca caagacctat tagcaaaaca agatacattg cgtcaagaat
    13921 ctgcacaatt agtaaaagac attgcagatt tacaagaacg tattgaaaaa cgtgaagata
    13981 caatccaaaa acaagcacgc gaagcacaag taagcaacac aagctcaaac tacatcgatg
    14041 ctgtattgaa tgctgattca ttagcagatg ctattggacg cgttcaagca atgacaacga
    14101 tggtaaaagc aaacaacgac ttgatggaac aacaaaaaca agataaaaaa gctgtagaag
    14161 acaaaaaagc tgaaaacgat gctaaactaa aagaattagc tgaaaaccaa gctgctttgg
    14221 aatctcaaaa aggcgatctt ttatctaaac aagctgattt gaacgtactg aaaacttcat
    14281 tagctgctga acaagcaact gctgaagaca agaaagctga cttgaaccgt caaaaagcag
    14341 aagctgaagc agagcaagct cgtattcgtg aacaacaacg tctagcagaa caagctcgtc
    14401 aacaagctgc acaagaaaaa gctgaaaaag aagcacgcga acaagcagag gctgaagcac
    14461 aagctactca agcttcatct actgcacaaa gctcagcaac agaagaatca tcagctacac
    14521 aatcttcaat gactgaagaa tcatcatcag ctacacaatc ttcagcaaca gaagaatcaa
    14581 caacacctga atcttcaaca gaagaatcaa cagcgcctga atcttcagca acagaagaat
    14641 caacaacagc gcctgaatct tcagcaacag aagaatcaac aacagtgcct gaatcttcag
    14701 caacagaaga atcaacaaca gtgcctgaat cttcaacaac agaagaatca acaacacctg
    14761 cgcctacaac accatcaaca gatcaaagtg ttgatacagg aaacggcaca ggaagtagta
    14821 ctccggctcc aacgccaaca ccaacacctg aacaaccaaa acctgtaaca cctgctccag
    14881 ctccttctgg aagtgtgaat ggtgcagcaa tcgtagcaga agcttacaaa tatattggta
    14941 ctccatatgt ttggggcggt aaagatccaa gtggctttga ctgctcaggg ttcacacgct
    15001 atgtttacat gcaagtaact ggtcgtgaca tcggtggttg gacagttcct caagaatcag
    15061 ctggaacaaa aatttcagtt tctcaagcaa aagctggaga cttgttattc tgggggtcac
    15121 aaggcggaac ttaccacgta gcgattgctt taggcggagg acaatatatc catgctcctc
    15181 aaccaggcga aagcgtaaaa gttggttcag ttcaatggtt tgcccctgac tttgctgtca
    15241 gcatgtaaga atgattaatc aaaaagagtt agcccattct ggactaactc tttttt
//
LOCUS       DAFEEZ010000069        14859 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.072, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000069
VERSION     DAFEEZ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.072"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(139..465)
                     /locus_tag="LP245_002307"
     CDS             complement(139..465)
                     /locus_tag="LP245_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520197.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(502..867)
                     /locus_tag="LP245_002308"
     CDS             complement(502..867)
                     /locus_tag="LP245_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBL1520198.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(904..1119)
                     /locus_tag="LP245_002309"
     CDS             complement(904..1119)
                     /locus_tag="LP245_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1520199.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            1248..1583
                     /locus_tag="LP245_002310"
     CDS             1248..1583
                     /locus_tag="LP245_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1520200.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(1659..3656)
                     /locus_tag="LP245_002311"
     CDS             complement(1659..3656)
                     /locus_tag="LP245_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520201.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(3754..4029)
                     /locus_tag="LP245_002312"
     CDS             complement(3754..4029)
                     /locus_tag="LP245_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1520202.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            4261..4995
                     /locus_tag="LP245_002313"
     CDS             4261..4995
                     /locus_tag="LP245_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1520203.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            5034..6176
                     /locus_tag="LP245_002314"
     CDS             5034..6176
                     /locus_tag="LP245_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1520204.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(6804..7289)
                     /locus_tag="LP245_002315"
     CDS             complement(6804..7289)
                     /locus_tag="LP245_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HBL1520205.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(7291..8727)
                     /locus_tag="LP245_002316"
     CDS             complement(7291..8727)
                     /locus_tag="LP245_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBL1520206.1"
                     /translation="MDKKVLIKRFSEAIEKGNAAIFAGAGLSMSQGYVSWPELLNDPA
                     TEIGLDSKKETDLVTLAQYYKNENGGSRGILNQILMDNFGEELEISENHRILASLPIE
                     TYWTTNYDHLIEKSIREAYKNPQVKKNYTQLATTNPNVDTIVYKMHGDIDDVSSTVIT
                     RDDYEKYDDDSYALFKETLKGDLLTKTFLFLGFSFTDPNLERILSDIRWVLRENQRPH
                     YCIMRKILKENFVDSEDFFDQERYNYELTKRRLQINDLSRFSINVVEVDDYSEITDIL
                     KSIRKKYLRKTIFISGSAVDYTPFTSESKGLKFVEKLAYRLSESGYRIVSGYGLGIGN
                     SIVSGVLKQRRNLRKNNIQDVLSLRPLPLDMPHEWRRYRENIIAESGISIFVFGNKLE
                     SGEIVTADGMIEEFELSVQNENIVVPIGFTKGASKVLFDKIQENFSDYFDDSLKSKFQ
                     ALEKLDTEGEVDKKVEQIVSLINSIQED"
     gene            complement(8760..9611)
                     /locus_tag="LP245_002317"
     CDS             complement(8760..9611)
                     /locus_tag="LP245_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HBL1520207.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            complement(9767..10012)
                     /locus_tag="LP245_002318"
     CDS             complement(9767..10012)
                     /locus_tag="LP245_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1520208.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            10117..10890
                     /locus_tag="LP245_002319"
     CDS             10117..10890
                     /locus_tag="LP245_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520209.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLNVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            complement(10943..11257)
                     /locus_tag="LP245_002320"
     CDS             complement(10943..11257)
                     /locus_tag="LP245_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520210.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(12776..12994)
                     /locus_tag="LP245_002321"
     CDS             complement(12776..12994)
                     /locus_tag="LP245_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520211.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
     gene            complement(13009..>14859)
                     /locus_tag="LP245_002322"
     CDS             complement(13009..>14859)
                     /locus_tag="LP245_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520212.1"
                     /translation="LVENSNNEFVATKFSDNFLSTFSDSLKSGYYRYQANLWGISIGL
                     TALAIAYVFSAFVIITAILELAFKRVLGVLVFATDIETGQRSKVVLSDILQCYLTVGF
                     QGFGLSMFAMFINFLNAGQGISTNIFIKTIAYICAVFVLIKGSGTVMRYFGVDIGLKE
                     GYGQLASAFGMGAMLFRKGSTGFNRAKGSGNGNGSDSGEGEDRKPEKNFGETLSKKAG
                     KTGRALGYAHERGLSGLASDGATMASERAIKPFKSMRDMANDTKNKFKEGLDDGTVSA
                     INKNSKPMLAKNKEDETGKYADSMPTRLSDRKDGAKVENADRIMSSSERMREAMKNNA
                     ESNNNPVSAIQQKVQQDIEERKNAMHGQAKSAEELINQKRQEAKYTPEAMNREEMLRK
                     RVEGRTGANTDEKEALTKERIQEAKNSNTGLEKLVKENLQNSTSSQGGRSVDVRENIQ
                     GSLNGHVGRNVDVRENLQSSSNGQGTKTIDVRENVQNSTSSQGFKSMDVRENVQNSTS
                     SQGFKSMDVRENVQSSTSSQGFKTVDVRENVQKDSGEMKEKTQKINIVEDRKSAKKFD
                     SNHETVIIDSEIRENDKGSKPRRRFTYEDNELFRDTLNDPNPLFDNLLKK"
BASE COUNT         4761 a         2729 c         2018 g         5351 t
ORIGIN      
        1 ctgctgttat aacagtgact aatgtaaaga ttttcccagc aatcatcaga ctattattta
       61 cagggaatca aaaaaactcc ttagtaagct tacaccttta ggagttcctg tttgaacggt
      121 atgcataata catttaaatc aatttaacat taacacctca gtatatggta tctctacata
      181 tacacggtct ttttttggat agtactcgac atttatattg atagcacttc cattgtctaa
      241 cgtagcttta gcccggtacg tgttatcacc attatcatga gtgatcgtca catcatcaca
      301 tgtccgattt aagttatact gttcttgtaa aatctgagtt accaatggta cagatgactt
      361 ctctagtcca gatgaacccg tcattcttga aaaaattata cctataatag ccaatacaac
      421 gatacctata atgacaaact tcttattcat atttacttta ttcaactttt tatctcctat
      481 ctccaaaatg attttctctc atcagtaact cattgacatc cccaatagta caccaaagat
      541 ggctccagct acccctgcta tcatcaaaat cgtacccatt tgttcatctt tctctcgata
      601 taagtaaccc ataataacag caacagcacc aaataccaca ggaataaatg ctaatgatac
      661 taccatagaa atccaaccaa taatcaaata cagcttccct gtctcttgtc catgtacgat
      721 ttgttccttc atttcattaa ttgtctgctc agtacttttc tttactgtgt ctgttccggt
      781 tgtctcatct gtttcttgta atgctccgca aaactggcaa tacttacttt catttgttat
      841 ttctttacca cattttctac aatacatgtc ttctcctcct aaaatcattc aattgcttat
      901 tagctaactg tttactttat taaatacatc agaaaacagc tcatttattg gtacacttaa
      961 tatctcagaa agcattttca tttgataggg tttaggaatc gttctccctg tttgccacga
     1021 acttacacat tgctgtgtaa cattcatttt tttggctaac tcagtttggg aaagtccttt
     1081 ttcttttctg tatcggctga gattacttac ttttttcatg attctcccct cctgttttat
     1141 tatatacaac aatatgatgt atttcaactc ataaaatata taaatacttc aaatgtcatt
     1201 acaaatacaa caacttgttg tactctactg agaagggggg tgtattaatg aaacagaagc
     1261 aatatgcaaa ggtcattaga gaaaagcgaa aagcactcgg gtggacacaa aaagaattag
     1321 ctaaaaaaat cttctctaca caacaggcag tagcaagatg ggaaaattct gtaacagaac
     1381 ctaacctcga tagcttaaca gctctttcta gagccctagg aacccctgta agccattttc
     1441 tagacaatgt tgacatagat tatgaggaag agtttttggc tctctatcgc tctcttagta
     1501 ctgaagatgc aattcgaaca attgactata tgaagctatt aaaaaggcaa gaaaatgaac
     1561 gcaatcagct attgaaagat tgaaaaataa ataacccacc gaactttaac ggtgggtgta
     1621 ttgagatgaa ataagattaa gagctatgga taacctgtct agtttaatat aattgggtct
     1681 cttctattcc ttactctccg tccatcatct cttgttacac ttgtaaattg ataaatagga
     1741 actaattcaa ctcctgataa tatcaattct tttattactt catctatccc tgcccctttc
     1801 gctagatata ctaaaaaact actgcttgct ttcacattgt atagtttctt aatatcctta
     1861 gaagctcgtt caagagtgaa tccttgttta acaaagtagc ctctgttttc tattaaagca
     1921 tttttcacgc tgttatccct gacatttcgt aggcgttcac aaacagtgtt aataagttct
     1981 ttttctgtca ttagatatgt cccttgccac gataagccct gtaaaacttc atgtgcttca
     2041 tctaaaatca attgtttttc cttgctaagt tctgatcggg aattttgagg aaatactctt
     2101 ttagcctctt tttcgttaaa acatatctta acccattcat aagaaaaata ttgatatgta
     2161 aaatgaaatt tttccagaag tggaaggata tcttcattca atttttgaat cacagaagtt
     2221 gcattaaaaa cgtctaatcg atagacattg cttctcttat gtttaaagtt tcctaacgct
     2281 ttctcttcct ttaacctatt taggtattcg agcatcttca aaggaacatc ttcatcatct
     2341 aattttttta tcaatcctat aaaagtcata agtgatagta acttattaca tttatctatg
     2401 tcataagttt taccatagta agaactcatt tttttagcta attgttcccc cgacaaaata
     2461 caagtcacac tttccttact atcatcaaaa aaattaacat cagaaagcaa gacatcatag
     2521 acacgtcgca tttcctctag ataattcctt attgtcctga aaagtttgtc tttcattgat
     2581 tcaagagtgt caaaaagtac ttttgattcc tctttcaatt ttcgaaaatg tgtaggatac
     2641 aagtctaggt tctctaatag ccaattaaat gtttctaccc gactgtcttt ctttaaaatt
     2701 agcatcacaa ctccaataaa attttcactg atatcacaat tactggaatg acaataaaaa
     2761 atggaatgcc cagttttact ggtaaaaata ctagcagagg gattatgatc gttgtgaaac
     2821 agacatctta agtttttact tgacttaagt aatttattca tatcaatggt taacaatctt
     2881 tcataaatct cattaaaaga catgtcggag gaatcaaaca ggcagtcttt aaaccactgt
     2941 ttcatttctt ctttgtcgtc attttttatc aacttaacaa aatcggtttc attgactagt
     3001 tcatactctc tccctgaatc actttgacaa tttttagaac atgtcatggt aaaatcaatc
     3061 ggaagctcag taatatctaa catgttgtct tcattaatta ttatcactgc atctgactta
     3121 tatcctccaa aaaacattct attcgaagca tttacattgt catcacaccc ggggatgttc
     3181 tttttcaagt attcgtaaac agcaaccatt ttaccatagt cagtaattgc ttcttttaat
     3241 agaaagacaa tcttgtattt ttctagattt tcagagtacc gaatactttt ttgtatcgca
     3301 aacgcagaat tatgaactaa attgatagat aaaacctttt ctatgcttaa gtatctacta
     3361 tcatctttac tcaaatctac taccttcccc ttctcatctt taacagtgtt atcgacatcc
     3421 agaataatta ctctggtttc cacaaaactc tccttgtcat tgcctttatt ctttgtcttg
     3481 cttggaataa atgattgtga tgaatttagt atctctacaa actcatctct tgtaacttct
     3541 ctatagttat ctaaacacct atctcttaca tcagtttttt ctttttttgt aactggcttc
     3601 tctaataatt tttctttatc tacataaatt ggaatattaa tcattgatgt ttccatttgt
     3661 gtttcctcct tataaaattc tgttaaagac taaaacatac agataataaa aacaaactct
     3721 ttattactat atgttttagt cttatttgtt tactcaacct ttataccgtt ccatgaaact
     3781 atcaatatca gattttttaa atctaatgac cgtatcaatt tttataacag gtaacccgta
     3841 ttgagaaaca tattttctaa tcgttcctac tgatacacct agatattcac ttgcctgctg
     3901 atagtccata tactctagag tgactccaga aataatgtct tctagcatag gctttagcac
     3961 tgtaattatc tctttcactt gttgttcaac ttgtatagaa acaatgctat caatgatttg
     4021 tagagacata tttccccctc ctttcgtgat tgcttgaaca aattttctaa gaattatctt
     4081 cgtatttttt gctcaaaata aaagtatttt gttattaacc gattaatcaa acaaaaaatg
     4141 attaccagtt catcgacata cacataatac ctcgataaaa aaggggtgtc aatagttttg
     4201 taaaatttat ttacaacacc ccttttttga ggtatactaa ttttaggagg tgtggtcaat
     4261 atgataaaac gtccaccaat aaattattta gaacgaaaaa agatactcgg aacaaaaata
     4321 aaagctataa gaaagagtaa aaaattaaca caaccagcat ttggtcttat gattaacaac
     4381 ggtcaattaa ttgacaaaaa gactatctac gaatgggaga agggaaccta tttaccaata
     4441 ccagagcgat tatcccgaat tgctgatttg ggaaatatga gtatagagga gttagtttgt
     4501 ggcaatgtag aagaatatat tttgggaatt attctttata gagatagcat tgtactagat
     4561 ggtataacat ttccagataa aaacctgttc cagcatcttc gtcaacagtt cccaccagta
     4621 cactctaatt tagatacatg gctggataga tattccaaat tagaaccaga gatgcaagaa
     4681 tttattgcta acaagacttg taataaagtt aaaaatgaaa aaattagtct tttcaatatc
     4741 ttaaaaatag aagaattatt catcaatgct attgtagaag aatttgacaa taacattctt
     4801 ttcctcacta gcagtataga agaactacta gaaagaatgg tagatgaatg gctacctatt
     4861 caattgaaag acatgtctta tcccgaagaa gctgtgagag aaattactga taatataaac
     4921 aagctagaac aaacgatttc atcaattggg aaaaaataca ctaagaaaaa aatgaaggga
     4981 ggtgatacca tctagtggta agtactcctt gtaaactaag aggagatgat ttcatggcaa
     5041 aaatatcaaa gtacaaaaag aaaaacggtc aagtggcgtg gatgtataaa ggacacattg
     5101 ccaccgatcc acgaactggt gaaaaaataa atactacgag aagaggtttt agtagcaaac
     5161 aagaagctca aaaagattat gacgagtaca gacatcaaat attatacggt gttaaaaaga
     5221 aagcacctga tatgacattt gaagacctgt ataatgaatg gataactcat cagcgtacca
     5281 gtgttaaagc ttcaacaatc gcaatctcag taagatacgc aaataatcaa atacttccag
     5341 catttggtaa gcttaaacta tcgaatatct ctgtcccata ttgtcaaaaa gtggtagatg
     5401 aatggcacag taaatatgaa agttacgatt atatgagaaa acagactgca caaattttac
     5461 gctacggggt tgcaatgcaa tatattgaca ataatcctat ggaaaaaaca cttcttccac
     5521 gaaaaaaaga gtatgagaaa aatcgtaaat tttactcaaa agaggagctt aataatttac
     5581 tggatgcttt taaagatttt ggtaacatga aacaatacgc cttcttcaga ttattggcat
     5641 acacaggtat gagaaagagt gaagtactcg ctttacagtg gaaagacata gacacgttta
     5701 ataaagaact acatgtcaat aaaactcttg ctgtagatga atttggtaaa gttataattc
     5761 aatctccgaa aacaagagct tctagacgag ttatctcttt agatactgag actctttcta
     5821 tcctcaacaa ctggaaatta cagcaaaaag aagagtattt aaaacttgga tacaatacta
     5881 gctctaaaga gcaacatgtt tttacaacag ttaaaaacac tctatacatt ccaaacactg
     5941 ttaatgattg gttaagatat attttgaaaa aatataactt gcctcgtatt acacctcatg
     6001 ggtttagaca tacacatgct agtttattat tagaagcagg agaatctgtc aaggtagttc
     6061 aacaacgatt agggcatgaa aatagtaaag tgacattaga catctatgca catattacaa
     6121 ataatgcacc taagaaaaca ggtcaagact ttgctgatat gatggctcat cagtaaaaga
     6181 gctggtcaaa atctggtcat ttctagtata caggcaaaac aaaaaagcta gaacccttat
     6241 atatcaaggg ttctagctcc tataacaggt ttacccaaca ctgccttcca atgactcttt
     6301 tgggaatcag aggaaagaat caggctttat agagatattt catctaacaa attactttag
     6361 actgacagta tatatcagca ggtactgtca tcgggaacgt agccaatatc gtatccaaaa
     6421 cagcaggtag agaagctatt tgaggattca agttattcta tttcaaccat gaagttaagt
     6481 tcattaaaaa taaagatagt tggtatttca ataatttttg tatagagtta atcactttat
     6541 tgatgctaat tcatcttgat tggtattata atcgtattca agttgcgtgg cgtgcttttg
     6601 ctagaaaata tataactgtt ctttataaag aaatataagg attaaacatt ttttatcata
     6661 gagttttact tatctataga attatgtctg ttcctaattc agtttgatga attaactgat
     6721 aaaaaaatat ctactattta aagatacagg gataagtaag taaaaaaata acatgtcatt
     6781 agatagtaga cagttccaac tctttattta ccttttttgt atgctgcact gtcaatccaa
     6841 gttcctaaat tgttgtatcc atcatcactt atataatcat attggccatc aataatttcg
     6901 tcaaaccaca aatattctcc atctggtttt tgcccaatta ttttaattac tgattgacta
     6961 gtagttgtca tctggttaaa atcttttatt ttacctatat taacggccaa aatagcattt
     7021 cctcgcttat aactctcctg gatttcatat ttaacatatt ctcgatcaag agtttcttta
     7081 cctatcagca ccacagtcac tgatgttcca attaattgat tatctatcca gttttttata
     7141 gcaatatctc cattacgttt aactttctca aattcagcct tatctacaaa accagcttcc
     7201 tttgttcctc gcaaagtcca gctgtttcta actaccattg ctcttgttac atctgcataa
     7261 tggaaactaa aaaaaaccct tctcaccata ttaatcctcc tgaatactat ttattaaact
     7321 gacaatttgt tcaacttttt tatctacttc tccttcagta tctaattttt ctagcgcttg
     7381 aaatttactt tttaaggaat catcaaaata atcactgaaa ttctcttgaa tcttatcaaa
     7441 caaaacctta cttgcacctt tggtaaatcc aatcggaact actatatttt cattttgaac
     7501 agataattca aattcttcaa tcattccatc tgctgtaact atttcacctg attcaagttt
     7561 gtttccaaaa acaaaaatac taatcccaga ctctgcaata atgttttctc gatatcttct
     7621 ccactcatga ggcatatcaa ggggaagtgg tcttaaagaa agtacgtctt gtatgttatt
     7681 ttttcttaaa tttcttctct gctttagaac tcctgaaaca atactattac caattccaag
     7741 tccgtaacct gatactattc tataaccgga ttcagaaagc ctatatgcta atttctcgac
     7801 aaattttaat cctttcgatt cagatgtaaa tggagtataa tcaacagcac ttcccgaaat
     7861 aaaaatagtt tttctcaaat acttttttct aatacttttc aaaatatcag taatctcaga
     7921 ataatcatct acttcaacaa cgtttatcga aaatctggac aaatcattga tttgtagtct
     7981 tctttttgtc agttcataat tatatctctc ttgatcaaaa aaatcctcag aatcgacaaa
     8041 attttccttt aatatttttc tcattataca ataatgaggt ctttggtttt ctctcaaaac
     8101 ccatcttata tctgataaaa ttctttctaa attagggtct gtaaaactaa atcctaaaaa
     8161 gagaaaagtt tttgttaaca aatctccttt taaagtttct ttaaataacg cgtacgaatc
     8221 atcatcatat ttttcataat catctcttgt tattactgtc gaactgacat catctatatc
     8281 accatgcatt ttataaacaa ttgtatccac atttggatta gttgttgcta actgagtata
     8341 atttttctta acctgagggt ttttataagc ttctcggatt gatttttcta ttagatgatc
     8401 ataattagtt gtccaataag tttcaatagg taaacttgct agtattcgat gattttcaga
     8461 tatttctaat tcttcaccaa aattatccat aagtatctga ttcaaaattc ctcttgatcc
     8521 accattttca tttttataat attgagccag agtaactaag tctgtttctt ttttagaatc
     8581 caacccgatt tctgttgcag gatcattaag tagttccggc caacttacat atccttgtga
     8641 catcgataat cctgcacctg caaatattgc tgcatttcct ttttcaatag cttcagagaa
     8701 cctctttatt aaaactttct tatccattct acccggttcc tttcgattca gtaaattgat
     8761 tagagattag tgaaaatggt gtttttatat aaaatatcta atgtattact tcctttagtg
     8821 cattccacag catctaaagc ccattttttc aaatcagctt ttcgtaaata agttaattca
     8881 cttaaattta aagaatattt tatttgcaga ttttcttgcg aagaatagtg ctttataatg
     8941 cttctaacat cctcggtgct catttgagga ttactttcca atcgtggatt ctttttttcc
     9001 actattgaag ctgtcgtcag ttcgctatat agccatggcg aatacgtaaa tttctgttca
     9061 ttagtgattt cattgctcaa actaattgaa ttaggtgtat taagaaaaaa cagacattct
     9121 gtactatcaa tcatattatt taaagctgta gaaagcatca tatgaacatg actagttgtt
     9181 acatttcttt tatcataatc atatgttttt gtttgttcct tatagcaata tttttggtct
     9241 atttttttta ataaatcaga actgtatccc caaaccgaag aatcaataaa tgcagtaaga
     9301 ccaaaatttt caaatagcca tgatgcaaaa cgtatagcta atttttcatc agcatgagag
     9361 tgagatataa aaatatctgc ttttatagtt ggaaaccaat ctttaataat ttcgtctgca
     9421 tctagaattt tgctgtcctt agaataataa tcaactaaat cattttcact ttcaaataga
     9481 ttttctattc tcttgttaat agatttttgg ttgtgatcta tttgatttac tacatgtgta
     9541 tatgattgcg agcttgagga gaatgcattt aagtcagcat ttgtaaaatc caattcatat
     9601 gccttataca aggatatccc tccattcttg tattttgatc cacaatttat taggcaacat
     9661 aacagtatac cctatcgtta catatcccat tcattattat accagtattt cttcgtgaca
     9721 cataagggtg taacataata atttcaaacg aaatgactac aagtagtcat tgaagcaaat
     9781 cttcataaga cacctgtaga atatctttga tggctttcaa ttgatccaac ttaatgtgtt
     9841 ggcggccacc ttcaatctta accaacgttt ccctagttat agcaatttta cgaagctgta
     9901 ggtctctaat cagctcggtt tgaccaattc ctttttctaa tcggactcgt ctaatattgc
     9961 taccgattac attttcttta tcaataattt tttcctcttt caagaatagc acaccttttg
    10021 gactaaaatt agtccttttt cttattaatc ttaaagattc ggtatgctac aatgggacta
    10081 gtattagtcc atattcaatt ttaaggagga atttttttga agaaatttgc aatcattcta
    10141 acttgcgctt tactcatcgg aactataagc gggtgtacca cttctgacac aagttctaca
    10201 agtacggaaa ctagtacaac aacctcagaa aagaattacc caatacattt ttttccggtt
    10261 ccagatggat ttgaagctta ttatcatgat aaaaaactaa atgttccttt atcagaaact
    10321 gaatctactg aaaagatttt gccaattgaa attgaaagaa atcaagacga tataaaacta
    10381 aaagctgatc ttcccttact gaacagcaca caaattgata gacatgaaaa tattaaagtt
    10441 aatattgaaa aaggagcgtt agcacaactt tatactgaaa aagttgaaca attttttgag
    10501 gctggtgcca ataaagactt ttcaaaaata agcgattatt cggataactt ttttaatgag
    10561 acccaagatg aaatcacgaa ctcaactttt atggctgaag atatgtacaa tatgaagttg
    10621 aaaaaaataa agtcgtatga ttatccatta aatctaacat taaataaagg gatactctct
    10681 tttgtattag caggttacgt tgactatgaa tatacagcag attatttgga gacgcccctt
    10741 caacacgata ataacgatat taattttaga tttatctaca attcaaaaag taaaacatgg
    10801 ttagttgatc aattgagcac tataaatacg ggatttcatg aattacctaa gcctgacaat
    10861 gaaactgctt tggtcattaa aacattctaa aaaagaaacg ttgaaggaat aattattctt
    10921 tcaacgtttc ttttattgtt tttcagttta cggtcttacc tgagcgaata atctgatttc
    10981 taaatgattg gaaaacttct tgtggttgat aataatctgt atctatttca aatgtttctg
    11041 agaataattc attgaatttt tctactgaaa tgatgatttt accattctcc tctcgactgt
    11101 tttctattat ttctgcctct aattcaaata aatctagtga cgaactaaaa tcataaatcc
    11161 tgtcatattg aacaaaaaaa tcaagaaaaa gttgctcaaa ctcttcctta tttatcacta
    11221 gtgtttcaag cggaacaact ttattttcat cagccattct tccaatttcc tcactttcat
    11281 tttcaattgt ccattgttgc ggacgtatca gattttctct atcatttttc agtgtataga
    11341 tcacttgtaa tacacaacaa tgctttgtaa acttattttt ttagttagtc gaatcttttt
    11401 aaatgtgcgt ttcataccat gcgcttgata tattttctcc tattttttaa atcgtttatc
    11461 acaactttta tcgttttttc ttctgaaaaa aatcttgttt acatcgttac atagtttcca
    11521 aaaagataca ttactagtag aaacaacaag attaatttta cttcccactg aaatgggaag
    11581 tatattttaa atattttttc tccttcaact tacactataa agtatcttaa tcacacgata
    11641 tgctagccac taaattcatc atatttgatt ccttttttaa gataatgtag catcttttta
    11701 tccaataacg caattgtttt taaggataaa tttcttaaga tggtacattt caaaatggca
    11761 tttgacatat gaaacaaaaa agaaagaaaa gagcataagg gaaaactgat agcaccttcc
    11821 tacaggaagg tggctaagtt ggctgtgcca actggttttc tttcaaaatc atttcataat
    11881 ttttgatatc ataaaaaaat ccattttgga cctattttcg gtcataattt agtacctact
    11941 tttggtcata gtttcgtccg tagttttggt catagtgact aaggcttttc tgttcacaaa
    12001 attggtttaa atttgctttc tttaacactt catttatatc atagcaatta taatgtttac
    12061 acaacatcat tcctaatttt aacggttgtt cctctttata ttttttaagt tctacatttt
    12121 tttgcgttta attacttttc tcttttcttt atattccgct ccaactttct ctttaatagt
    12181 gataatagaa ttacatattt ttgttaaact tccttaaaaa aattggatct cgattactca
    12241 aatttgcttg caggcttttc taattgcttt gttttttctt cctaattatt tgattttatt
    12301 tccattttct tctagtgaaa atttattatt tttaataatc gtacgcgtag aactgatttc
    12361 attttttgta tctgtttgat tatctaacgt ttgaaattca aagttttgat tggctttatc
    12421 aatatctttt tatactactt tatttgcaag atatattttc ttgcttaatt tggtcatagt
    12481 ttcattcgtc acttcggtga tattttttta atttgcaaat aaaaagagtt aaaccgatat
    12541 acattaggtt caactctttt gcaggtttca tgggtgtact atcactttta atctgataga
    12601 tgtaaacctc tctttatctt tttgttactt caattttcaa caatagctcc tttataggtt
    12661 gtcaatattg ctctacgtat tctggctttt taacccatta tttctctaaa gtggaagaga
    12721 ataatcgctt aatccccact aattccttgt cgtaaattca tgtcaaatac aatttttaaa
    12781 agccatttaa ttcatggatt atctcttcac ttttttctag ataacaatat ttcaagttgt
    12841 tttttatctc atgtttcatc tttaattctt cttgaatcat cagttcaata taattagtga
    12901 ccgtgatttt ttcatttgtt gcgttcttta ctgattcaca taattcgtca agttctaaga
    12961 aatcatgcgt actaatcttt agaattaatt tcatgacaat tccccctttt atttttttaa
    13021 tagattatcg aaaagcggat taggatcatt aagtgtatct ctgaataact cgttgtcttc
    13081 ataggtaaat cttcgtcttg gttttgatcc cttatcattt tcacggattt cactatcaat
    13141 aatcactgtt tcatgatttg aatcaaattt tttcgctgac tttctgtctt caacgatatt
    13201 gattttttgt gttttttctt tcatttctcc actatctttt tgaacgttct cccgaacatc
    13261 tactgttttg aatccttgac tacttgtaga actttgtaca ttctctctta catccattga
    13321 tttaaaccct tgactacttg tagaattttg tacattctct cttacatcca ttgatttaaa
    13381 cccttgacta cttgtagaat tttgtacatt ttctcgaaca tcaattgtct tagtaccttg
    13441 accatttgaa gagctttgta aattctctct tacatcaaca ttccgtccga catgaccatt
    13501 caatgaacct tgaatatttt ctcggacatc tactgatcgg ccaccttgac tacttgtaga
    13561 attttgtaga ttttctttga ccaatttttc taatccggta tttgagtttt tagcttcttg
    13621 gattctttct ttggtcaacg cttctttttc gtccgtatta gctcctgtac gcccttctac
    13681 acgtttcctt aacatttcct cacgattcat tgcttcaggc gtgtatttag cttcttgtcg
    13741 cttctgatta attaattctt cagcagactt agcttgaccg tgcatagcat ttttacgttc
    13801 ttcaatatct tgttgaactt tttgctgaat tgcacttaca ggattattat tcgattcagc
    13861 attatttttc attgcttcac gcatacgttc agaactagac ataattctat cggcattttc
    13921 aaccttagca ccatcttttc tatccgaaag acgtgttggc atggaatcag catattttcc
    13981 agtttcatct tctttatttt tagctaacat aggtttgcta tttttattaa tagcggacac
    14041 tgtaccatca tctaaacctt ctttgaactt attcttggta tcattagcca tatcacgcat
    14101 actcttaaat ggttttattg ctctttcact agccattgta gctccatctg aagctaaacc
    14161 tgataatcca cgttcatggg catatcccaa agctcttcca gttttgccag ctttttttga
    14221 tagagtttcg ccgaaattct tttctggttt tcgatcttct ccttctccac tgtctgatcc
    14281 atttccattt ccgcttcctt tagcacgatt aaatccagtt gatccttttc taaacagcat
    14341 tgcgcccata ccaaaagcag aagcaagttg cccatagcct tctttgagtc caatatcaac
    14401 accaaagtat ctcatgactg ttccactgcc ttttatcagc acaaacacag cacagatata
    14461 agcaattgtt tttataaaaa tatttgtgga gataccttgt ccagcattta aaaaattgat
    14521 aaacatagca aacatagata gtccaaaccc ttgaaatcca actgttaagt aacattgtaa
    14581 aatatcggat aaaacaactt ttgaacgttg tcctgtttca atatctgtcg caaaaacaag
    14641 aacacctaac acacgtttaa atgcaagttc taatattgct gtaatgatca caaacgcgct
    14701 gaacacatag gcgattgcca acgctgtcaa cccaatcgaa atcccccaaa gatttgcttg
    14761 atatcgataa taacctgatt tcaagctatc agaaaatgtt gataagaagt tatcagaaaa
    14821 ctttgtggca acaaattcat tattagaatt ttcaactaa
//
LOCUS       DAFEEZ010000070        14840 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000070
VERSION     DAFEEZ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14840
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.073"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            418..1032
                     /locus_tag="LP245_002323"
     CDS             418..1032
                     /locus_tag="LP245_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1520213.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            1805..3544
                     /gene="yfcC"
                     /locus_tag="LP245_002324"
     CDS             1805..3544
                     /gene="yfcC"
                     /locus_tag="LP245_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBL1520214.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            3701..4885
                     /gene="iadA"
                     /locus_tag="LP245_002325"
     CDS             3701..4885
                     /gene="iadA"
                     /locus_tag="LP245_002325"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBL1520215.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            4996..5199
                     /locus_tag="LP245_002326"
     CDS             4996..5199
                     /locus_tag="LP245_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBL1520216.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(5300..5962)
                     /locus_tag="LP245_002327"
     CDS             complement(5300..5962)
                     /locus_tag="LP245_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1520217.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(5975..7477)
                     /locus_tag="LP245_002328"
     CDS             complement(5975..7477)
                     /locus_tag="LP245_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1520218.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            8025..9704
                     /locus_tag="LP245_002329"
     CDS             8025..9704
                     /locus_tag="LP245_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBL1520219.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            9831..10310
                     /locus_tag="LP245_002330"
     CDS             9831..10310
                     /locus_tag="LP245_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBL1520220.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            10529..11209
                     /locus_tag="LP245_002331"
     CDS             10529..11209
                     /locus_tag="LP245_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBL1520221.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            11217..12548
                     /locus_tag="LP245_002332"
     CDS             11217..12548
                     /locus_tag="LP245_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL1520222.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            12563..13525
                     /locus_tag="LP245_002333"
     CDS             12563..13525
                     /locus_tag="LP245_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBL1520223.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            13636..13974
                     /locus_tag="LP245_002334"
     CDS             13636..13974
                     /locus_tag="LP245_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBL1520224.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            14053..14760
                     /locus_tag="LP245_002335"
     CDS             14053..14760
                     /locus_tag="LP245_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBL1520225.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
BASE COUNT         4762 a         2578 c         3192 g         4308 t
ORIGIN      
        1 tttttttgta ttttcttgct tgcacttgga taagagatta cttacaataa attcagatag
       61 aaacagctga ataaaaaaag gctccctgac ccttagttgg cgctaagaat cagggaatga
      121 ccagtcacac acatacaccc tgaccgatca ttttgccata gtcaatgcag tgcatcgacc
      181 taatttattg tacctaatct agggtgaaaa ttctacccct atgtagatat tttccatggt
      241 ctgcacgttg ttttatttgc tatgtcaagg tattgggcgt attcgttcaa tgcctttttt
      301 gtgtttgaaa cagcaaagac cacatgtgtt actgtctaac tactgttttt ttatgtactt
      361 ccttagatta ggcagctgtt tctattcatg tcaagtatag ctaggcggga gagataaatg
      421 agtttatgtt attttgacta ttatcaccaa ttggaagaga aattaaggat agaagagccg
      481 ctgatgcttc aagctggcac ttggatcgcg aaacaaatta atcaaggtgg tagattgcag
      541 atatatgcta gccgcacact aagtggtgta gcatttgaat tttgggatca aaccccggat
      601 cttgtaccaa gtatattgat tgaaaatcca gccggaggtg tctatgaaac gctagaaggt
      661 gcaggacagg caattattga tcagctttct gtcaaatcag aagacatttt tcttcttctt
      721 tcgaatgaag gaagaaaccc ggcaatcatc gaactagctc agtggatcaa agaaaatggt
      781 catccattaa tcattgttac tggatttgat ttgtcacgaa gtatcaaatc gcaacatagc
      841 agtggtttgc gattatttga atttgctgat ttggttttgg acaaccacgc caatttacat
      901 gatgcagtct tgactttgcc aaatctagat ccagcgatct gcggaacagc ctctcttgca
      961 acgatctttt tgctgcagca agttttgtat tttacagcaa aacagctagt ccaggacaca
     1021 agtggaaaat agttatccac atgttgacaa agttccttaa aaaaataatg ttccacataa
     1081 aaatggagcg tttgaaaaaa agaaaacgat tattaatgag gattaacaac gactactttt
     1141 tttgttttag ttattttaag atggatcatc tttgatttta agcttgtttt gtttaaagtt
     1201 tgttattttt ataagttgtt tcacagttat gagaaatgag ttataagaat atgtagtgtc
     1261 agaaaaataa aaagtagtgg aaaaagagac aagaaagaat ccatatggat tctttcttgt
     1321 ctcttaatac acgttgatga aagagtcttc cccaaaactc tttacaaagt aattatagta
     1381 catttgttat cattattgca atgaagttta cctgatataa caaaattgtc caacaggata
     1441 cctttttcta atagaaataa aatacacaaa aattgaagga tagataatgg atatttataa
     1501 gtgtttatta ttttttttgc aatgaaattc aatttttcaa tgattgtaaa atgaaaaaaa
     1561 caggacgaga ttttctctaa tctaaaaata aaaaaagaat tttaaggaaa aacagagaaa
     1621 taaaatactt aatataaatg gaaagagaaa aaaataatca tacataggag aaaaaaaaca
     1681 aaatagaaaa aagtgatttt ctaataaatt attcatgtgg aaatgtcatt tttactgtat
     1741 aattcatttg attatccatt ttttattcat caaaattact gaaaaaagaa aggaagaaat
     1801 aaatttgaag aaaacaaatt cttcaggaaa accgaaacgc gacttcacta aattatcgac
     1861 accccatacg tatgtcatta tttttggtgt agtcatcttt gcatggatac tgacttttgt
     1921 cgttccagca ggaaagttca gcacgcaaga tattgaatac aaagatgcaa atggcgaaac
     1981 aagtactcgt actgttttac gtcaagattc cttccgttat gcttacgagc tggataagtc
     2041 gtatgtgttt gatcaattag aagaactgca agatcatcca gcagaacgtg aaaaactgga
     2101 tgttccggaa aaaggattgg aaaaagtcat tgctgacgga gaaaaaaatc ttacgcagga
     2161 aaaactagat gaaatctcct tgacagatga tgtgctttac gatcagtacg gcgaaaatat
     2221 ctatgatact tctaaaaaat tgcataaaac agccaaaata tggggaacag atgattttgg
     2281 cggctttggt ttcttaaatt ttgtttttga aggactagta tctggagata agtatggatc
     2341 tgctgtaggg atcgctgcat tgatccttgt tgttggaggt gcttttggta ttattatgcg
     2401 taccggagcg atcgacgcag gtatctatgc gtttatcagt aaaactaagg gactggagcg
     2461 tttagcttta ccgctattat tctttgcttt ttcattcggt ggcgctacat tcgggatggc
     2521 agaagaggta attccattct caatggtgat ggttccattt gtcattgcgt taggatatga
     2581 ctcgatcgta gcagtaaccg tgacttatgt cgcatctcaa gtcggaaatg cgacctcttg
     2641 gatgagcccg tttagcgtag cggtggctca agggattgct ggaatccccg tgttgtctgg
     2701 tgcgacattc cgattgatta tgtgggtagt tgttactgca ttagccgctg gttatatgat
     2761 gatatatgca gaaaaaatcc gtaaaaaacc agaaagttcg ttgacttaca aatcagatga
     2821 ttatttccgt tctcatatca aaaagacatc tgatgaaaat aaaaaattca tgcttgggca
     2881 taaattgatc ttattagaga tgttagttgt ccttgtctgg atcgtttggg gcgtgactca
     2941 aaaaggctat tacattccag aaatcgcttc tcaattcttt gtgatgggat tagttgctgg
     3001 aatcattgct gttcttttca aattagatgg aatgaaagtc aatgacatcg cttcttcttt
     3061 ccaatctggt gcagctgatt tagctggtac agcaatcgta gtaggtatgg ccaaagggat
     3121 tcttcttgtc ttgggaggat ctgatgcatc tgttccttca gctttgaata cgattttgca
     3181 tgggatcggg acggcgttga ccggtgttcc agctgtcatt ggtgcttggg cgatgtacat
     3241 cttccaaagt ttgttcaact tggttgttac atcaaattca ggacaagcag ctttgactat
     3301 gccaatcatg gctccactgg cagatttagt aggtgtatcc agacaagtag cagttcttgc
     3361 ttatcagctt ggttcaggtt ttatggacgc ttttacaccc gtatcagcca gcttgattgg
     3421 tgtgctaggt gttgcacgga tcgaatgggc aaaatgggca agattccaaa tcaagatgca
     3481 aggattcctg tttgttttag gaactatttt catcatgatt gccattgcaa taggtctgca
     3541 gtagtactgg agacctgtaa ataaaaaagt aatccaaaca gtagataagg actccaagaa
     3601 ccgtcatttt acggtaaaat caaaggagta aagatcctat cgtttggatt attttttaag
     3661 atcctatcat cagttatact taaagaaaga ggaaaaatgt atgaaaatca ttcgacaaat
     3721 tgaagtgttt gcaccagatt acttaggaaa aatggatgta ctgattgccg gtgggaagat
     3781 tttggctgta gaagaacagc tagaaggcgg ctacgaagga gtggaagtag aagaactttc
     3841 aggtgaggga aaagtactaa ccccgggttt cattgactgt catttccata ttttaggtgg
     3901 aggaggagaa ggcggttatc aaaatcgaac gccagaagtc acattgagcc aattgactac
     3961 agctggtgta acgacagttg tcggttgttt gggaacagac ggagaaggta gagatatgac
     4021 tgcgttgatc agcaaagcga aaggtctgga agcagaagga atctccactt atgtatacga
     4081 aggttcgtac cgattgccgg taaaaacagt aacagattct atcatcaaag actttttgac
     4141 aattgataaa attatcggaa tcggagaaat cgcagtatcc gatcaccgtt cttctcagcc
     4201 aagttttgaa gagttcgctc gtgcagtagc agatgctcgt gtaggaggca tgttatccgg
     4261 aaaagctggg atcatcaatg tccacttagg cggaggaaaa agaaagctag agctattgac
     4321 acgaatcgta gaagaaacag aaattccgat cacacaattt ttgcctactc atgcaaatcg
     4381 cacaccagaa ttatttgaag cttgcgtggc atttgccaaa cgtggtggca cgattgactt
     4441 cactgctagc gaagatcctg atttttggga gaagacagat ggtgaagttc gcttcagcaa
     4501 agcactgaaa cgattgatcg aggaagatgt ttctttagat aatttcacga tgacctcaga
     4561 tggacaagga agcttgcctt attttgatga aaacaatcat ttcctagggt taggagtagg
     4621 aagtgccaag gcattgctag tagggatcaa agaagctgtg caaaaagaaa gtatcccttt
     4681 ggaaatcgcc ttacgagcta taaccagtaa tccagcacgt atattgaaat tggataaaaa
     4741 aggaaaaatc gaaattggtg ctgatgcaga tctgtgtatc ttggataaag aaacgcttga
     4801 tattgataca gttatcgcta aaggagaaat aatggtccaa gaaaaagaag tcaaagtatg
     4861 ggggactttc gaaaaaagtt tttaatcaac agctctaact atctttttta gaaaacgagc
     4921 gttctgtttg tctgtatctg ttgttgatgt taccctgaag gtagatcaat aaacaaacta
     4981 agaggaggaa gcacaatggc agatttaaaa ggacgttcta aagatatgaa agataaagta
     5041 gtcggtgaag gaaaagaagc atacggcaaa gcaacagacg acaagagcaa agaaacagaa
     5101 gggaaagcac aatcactagg tgctgacatc aaagaaaaag ctcgaaattt aggcgacgaa
     5161 gtcaaagaca agttttctcg aaaagacgaa aaaaaataaa aaccacttat tactaattga
     5221 atcaagcaaa taaaaaatcc gaaccatatc tgcgagacag atatggttcg gattttttat
     5281 ttgatcatta tcctgttttt taaacttcga ttttttgaaa ttttttattt tttagttcaa
     5341 agacttcatc acagcttttt gctacttcaa tctcatgagt cacgatgata atacagcgat
     5401 tttgttcatg ggcgatttct tggaaaagtt tgacgatatc ttgtgaagtt gtttcatcta
     5461 gatttccagt aggctcatcc gctacgatta gttgatgttc acagcagata gcacgaacga
     5521 tagcgactcg ctgctgctga cctcccgaaa gtttggtcac ctgttttttt gctaatattt
     5581 catcaattcc tacacgagcc agtcgatcta aagcaacttg tcgataattc tcttgcttgg
     5641 tcttagtgat ttccattgct gctatgacgt tgtctagagc cgataaataa ggaagcaagt
     5701 tgtaagcttg gaaaataatc gagacatcat ttttacgata acttcttaac ccgattttgt
     5761 tcagtgaacg atcttgatag tatacctttc cttcttttgg tgcatctagt ccagaaataa
     5821 gcgaaagaaa agtcgttttt ccagaaccac ttgctcctaa aatagcgtac atttttccag
     5881 cttcgaaatt cagttctaca tctttataaa gcgcatcttg cggatcttga taccaaaatc
     5941 ccaattgttc tgtccgtaac atcaaattcc tcctttagtt taataggatt tttcttgggt
     6001 ttaatcttaa tatccctata gaagctaaaa agacagaaaa cagactgatt ccaaatgcta
     6061 ctccggctaa tagtcccaat tgtgcaggtt tgacattgat ttccaattcg ctgacttgat
     6121 cagaaacagc aaatggatta ttcgtggttc cttgttgacc atcgcgttga ccgccttgtt
     6181 cttgtctgtt acctggcatt tgtccaccgc caggagcttg ctggttttgt gtcgtggttt
     6241 ctgtctgttg gtcaagtagc tgctgtccca cggcattcgc gacgacgttt ccgctaagcg
     6301 aagcaactcc taatgcaaga atcatacaaa tagccacttc ggtaaacaat tggagaatga
     6361 ttttacttct ggattctcct aaagatagca agacgcctaa ctcatgccga cgctcccgaa
     6421 tggtaatcat aatgatcaga gtaagtatga taataccggc tacagccact agtaaaacaa
     6481 catttttaga aaaacttgcc acgttgttta aaggttccaa cattgactga tacatggaat
     6541 catttgattg taagctaaat gtatctgtgt cgatcagctt ctcagcttct ttgagaaact
     6601 catccatttt atctggatca gatagagtgt aaatagcaga atctatcgtg ttatcgtcag
     6661 atgtcccatt tagttcattt gcaaaagtgt aagaagtgta aagtgtattc gacggattca
     6721 tgaagttgaa tttcataccc atactgccgc ttgtttcgct ggattcataa attcctttga
     6781 tcgtcatttc ataagtggta tcttcatctt cagtactcgt gattgtgaaa gtatctccga
     6841 ctgccaggtc atttgtttct gctagagtag aatcaatgac tacattgttt gtgcctttgt
     6901 cgctgtcatc tattccttca ccatccgtga tttttgctgt tccatcagaa aaattactat
     6961 tttgtgcagt tgctgacaca ccactgattt gaaagtctgc ttgagtcatt tgcggattcc
     7021 cgcccattcc tccagcaggt tcaccgcctg catcagtagt ttctgaactg tcttcacttg
     7081 aatcagaact agtgatggca gttattccat cttttgccat agctgaggcg gaactttcaa
     7141 aggaataact ctttacatta tctaattcag ctattttttc cgcgtccgtt aaggaaactg
     7201 gtgtaagaga aaaactgcct ggatctggac gttcttcagt ggtagaaccg cttgaagaag
     7261 tttgttcctg ttttttaaat gaagcttctc gattggcact taaagtcact gttgctccaa
     7321 cttctttttg tgcttgattc gctgcttctt ctgcagcgct tcgaatcgtg aggccagcta
     7381 gcacaaaaat aagaatggct gtgaacacgg caaacaataa caatgaacgt ccccatttta
     7441 cttttgtact tttccatgca cgtttcataa aattcatatt ttgcatccct cctagtagat
     7501 gcatttgata atagacaacc tatcttaaag ctagcttaaa tcttatgctg tttgcacacc
     7561 atcaacatga ggttctgtat atataaaaag tcactatagt tattgcaaaa aatgtggtaa
     7621 aatgaaaaaa gtatgtttca aaccgacgaa gaagaaatga aagaggaata gcaaaagaaa
     7681 tcctagatgc tacagaggga tttttacgtg catagttgtt ctaacaattg ctgatactag
     7741 cgatttagtt tatttgttgt ataataatgg ggaacagctg aatacttata taagtattct
     7801 ggctatagcg tttcgcaaaa gatccatttt gttaatgaag tatatccaaa ataaaatgcc
     7861 catccaactg tcagaacgcg gatgtgctgg taattttcct gctgattctc cataagttga
     7921 gaaatagtga ttttgcatat gcttcattgg aatggctcat atatttagat aaagaagaaa
     7981 atcgacatct ttaaacttgg atgtcataag aagaggtgaa gtttgtgagt accattaaaa
     8041 ttatcccatt aggcggcgtt cgtgaaaatg gaaaaaacat gtatgtcgca gaagtgggcg
     8101 aggatatttt tattttagat tgtgggctaa aatatcctga aaatgagttg ttggggatcg
     8161 acgtcgtaat ccctgatttt acgtatttag aagaaaacat tgatcgtgta gctggtgtct
     8221 ttttaacaca tggacatgca gatgcgatcg gggcacttcc ttacttgttg tcaaaaattt
     8281 ctgtaccagt attcgggaca gagttgacga tcgagttagc aaaattgaat gtcagtcgta
     8341 atgaagcagc caaaggattt aaggatttcc atgtggtaga tgagcataca gaaatagact
     8401 ttggtgaaac agtagtgagc tttttccgta ccactcatac gataccagat tcagtgggga
     8461 tcaatctgaa aacaaaagaa ggtagtatcg tttatacggg agattttaaa tttgaccaaa
     8521 cggctatccc aatgtatcaa acagattatg cacgattggc ggaaatcggc aaagaaggag
     8581 tcttagcctt actaagtgaa tcggcaaatg cagaaaatcc tcagcctgta gcttctgaag
     8641 cccaaatagc agatgaagta tttgatacga tcaaatattg ggaagggcgt atcatcgtcg
     8701 cttgtgtagc aagtaatttg caacgagtgc aacaagtatt ggatgcagca gaaaaagcac
     8761 aacgaaaagt tgtcttgact ggtcaagatt tcgaacgaat tattcgcaca gcgatgcgtt
     8821 tagaaaaact tcaattacca agtgaagatc tgcttgttac gttgaaagac atgaaaaact
     8881 atgatccaga agaactgatc attttagaaa ctggccgaat gggtgaaccc atcaagtctc
     8941 tgcaaaaaat ggcaaacggt acacaccgta atgtcaagat tgaagaagga gatttggttt
     9001 atatcactac tacgccaagc atcgcgatgg aaaccatcgt ggcgaaaacg gaagatatca
     9061 tttatcgagc tggtggaaca gtgaagttga tctctgagaa tatgcgcgtt tctggccatg
     9121 ccaatcctaa tgacttgcaa ttaatgatca atttgatgaa accaacatat tttgtgccag
     9181 ttcaaggaga gtatcgtgaa ttagctgctc atgcagattt ggctcatgca gtagggatgc
     9241 catacaaaaa tatctatatt actggacgcg gagacgtgct ggaatataag aacaagcgta
     9301 tgagtgttgc aggaactaca agtgcagaaa atgtaatgat tgatggatta ggcataggtg
     9361 atatcggaaa cattgtttta cgtgatcgaa aaatcttgtc agaagacggg attttcgtag
     9421 cggttgtcac tatcagtcgg cgagaaaaga aaatcatttc aaaacctcaa attacttcac
     9481 ggggattcgt ttacgtaaaa gctagccgtg atctgatgaa agaaagcagc aatatgattg
     9541 aaacaatcgt tgagaaacat ttagaaagca atgattttga gtggagcaaa ttaaagcaag
     9601 acatccgaga tcaattaggc cgttacttat ttgaacaaac aaaacgccgc ccagtgatct
     9661 tgccagtcat tatggaagct actcaacgtc gaaataaaaa ataaacaaaa agagtaagat
     9721 gaacctctct atagagtgct cgtcttgctc tttttttgcg aaaaacaaat aatttttgaa
     9781 tacagcatcc ctcgctttat aataaacgat agaataaagg gagtgaatca atgatgagtc
     9841 aaacaaaagt cgaacgttat ttagaagaac aaaagatcag ctatcaacca cttgatttta
     9901 gtcatgtggt agaagaatct ttcacagaag aactacaaaa aagagggatt gatccagctt
     9961 tgatatgtaa aactctcgta gtgaaaggaa acaaaactgg ggtgatcatc gcattgattc
    10021 ctttgaacga tcacttagat tacaaaaaaa cgagacaagt gacgaaagat cgtaaagttg
    10081 gttttcctgg aatggatttt gtattaatgc atacaggata tccccacgga gcaaacaccc
    10141 ctattggaat aaaactcgca catcctgatt attgtttttt agcagacagt tctttaaaag
    10201 aaaaagaaga agtaattgtg tcaagcggtg aaatcgggag aagccttcgg ataaaagtag
    10261 ccgatttaga aaagatcgtc catcctattt acgctgattt aattagttaa gggacgagaa
    10321 gagaagctaa gcagagcaga gacctcaaac ttgagattat atctgcttgg tacttggtgc
    10381 atcctgtatt atctgttaca attgctttgt acatactgta ctatcaatcc aatgaaaata
    10441 tatttagcag ctatattttt tcattgatgt gcaagtgatg aaatcgtttt taataaaaaa
    10501 gatacagaga aaacgcgagg tgtaaaatat gaaaattacg tatcatggac attcctgttt
    10561 aacaattgaa atggaaaatg gccaacgcgt gatgattgac ccgtttatta caggaaatcc
    10621 attgacagac ttaactgcag aagaagtaaa gacagattgg ttgctgatta ctcatggtca
    10681 tagtgaccac ataggagata tgattcctat tgcaaaagaa aatcaagcca caattatcag
    10741 tattgttgag attgctgatt atgcgaacag cagaggagta gattcattcg gtatgaatat
    10801 cggtggaaaa catgcgtttc cattcggcgt ggtaaaattc gtacatgcac agcatagttc
    10861 aagctatgaa gtagacggta tcgttcagta tatgggcgag cctagcggaa ttattattca
    10921 agcagaagga aaaacgattt atcatgcagg ggatactgct tatttcagtg atctaggatt
    10981 gcttgcagaa gaattcgata ttgatgtcgc tttcttgccg attggcgata actatacgat
    11041 ggggccagaa gatgcagcaa aggctgcgca aacaattcgt gccaagaaag tagttccaat
    11101 ccattacaat actttccctg tcattgaaca agatcccgaa tcttttgtag agttactgga
    11161 agatagtgaa ggaaaaataa tgagcgtctc ggaaacgctg gaagtgtagg cagaaaatgg
    11221 cgacaaaaca tgatttgatt ttagaatata ttgaaagttt acctgttggc aatcgaattt
    11281 ctgtaagaag catcgcaaaa gaattgaatg tcagtgaagg aacagcgtac cgtgcaatca
    11341 aagatgcaga aaatgtcgga ctagtttcaa caattcaacg agtagggacc atccgtatcg
    11401 aacgcaaatt aaaaaaacat attgaacgtt tgacatttgg cgaggtcgtc aggatcattg
    11461 aaggggacgt tttaggcggg gcggcaggat tagacaaggt cttgaataaa ttcgtcatcg
    11521 gcgcgatgac taaacatgcc atggaacgct atattacgcc aggatcacta atgatcgtcg
    11581 gcaaccgggc ggaagtccaa aaattagcat tggaagatgg cgccgcagta ttgatcacag
    11641 gaggattcaa tacgactgct gagattgcaa agctagctga tgatcttgaa atgccgatct
    11701 tacgcacctc ttatgataca tttacagtcg caaccatgat caaccgagcg ttaagcgacc
    11761 aattgatcaa aaaagatatc atgcttgtca gtgatatcta tatgccagct gaaaagactc
    11821 attatttgca gcagacagat acgatttctg attatcagcg tttgtcagaa gaaacgcagc
    11881 attcgcgttt tccagtcgtc aaccgccatc atcgtttgat ggggattgtt acggcaaaag
    11941 atgttttagg gaaatcgcca aaccagatca tcgatcgggt gatgacgaaa gaaccaatca
    12001 gtgtaaagaa aacaatgagt attgcctctg ttagccatca aatgatctgg gatgggctag
    12061 aagtcatgcc ggtcgtttcc gatgacttga cattggaagg cttgattacc cggcaagatg
    12121 taatgaaagc gatgcagctt gtccagcgac aaccgcagat tgcagatacg atttcggatc
    12181 agatatctgg aaatatccat acgattgata ctgaccgtga aggaaatcgt ttggaaaacc
    12241 ctaagttcaa attcgtagta gcaccacaaa tggtcaatgg cgttggaacc atttcttttg
    12301 gcgtacttag cgaaatcatt tctgatgtcg cacaaaaaac aatggtgatg aaccaaaaac
    12361 gaaatatctt gattgaacaa gtgaacctac attatttgcg gctgatccaa ttggaaagcg
    12421 aattagacat tcgtccacgt gtattggaaa tcggcagacg ttccgctaaa ctggatatcg
    12481 aagtgtttat tgaaaacacc atcgtttcca aagcaatcgt tgtttgtcaa gtaatggaac
    12541 gttcttagaa agcaggagtg aaatgacagt acagcaagaa atagtagata caataaaaaa
    12601 atacgataaa atcattatcc acaggcattt gcgccctgat cctgatgcat taggatcaca
    12661 agtaggatta gccgaactat tacgggaaag tttcccagaa aaagaaatac gtcaagtagg
    12721 tgaaacgatt gaagggcttc gctttttagc agaaatgcaa gaagttgaag atgtcttcta
    12781 ccaaggagcg ctagtcatcg tgactgatac agctaattca cccagaatca gtgatcaaag
    12841 atatcagttg gcagaaaaac tgatcaaaat cgaccatcat cccaatgatg acccttatgg
    12901 agatcttgtg tgggtaaata caaaagcaag tagctgtagt gagatgattg cagaatttgc
    12961 tttgatgttt cctgaatctt taaagatgaa cgttaaggct gcacggttac tttatgcagg
    13021 aatcgtcgga gatacagggc gctttttgta tccctccacg acgtcccgta cattagagat
    13081 tgcttcgata ttgagaaatt atccatttga tgcaagtgct ttgaacagag agattgaaca
    13141 aatgccgatg aaagtcgcta aactttccgg ttatctttat caaaatatcc aggtggatga
    13201 aaatggtgca ggaagaataa tccttccgca agaaattctt gataaatatg gaatcgatga
    13261 ttcagagaca gcttcgatcg tttcacttcc tggagtgatt gacgaagtgc tggcttgggg
    13321 gatttttgtt cagcagcctt cagggtatta ccgcgtacgt ttacgttcta aggggccgat
    13381 catcaatgaa ttggctaaac gccatcatgg aggaggccat ccattagcaa gtggtgcgaa
    13441 tgcaaaagat ttagcagaag tagaggaaat ctataaagag atccaagata tatgccaatc
    13501 gtataagagc agaaaaacag aatgatactt cgttcgaaaa cgtgcctttt gtagtaaaaa
    13561 tcacaaatgt atcttttcaa gatcttcttt ttccgttaca atagtgctca ctaaagattt
    13621 taaaggagaa agaagatgac attaccaaat tgcccagaat gtggctcaga gtacacatat
    13681 gaagatcgag gcttgttgat ttgcccagaa tgcgggaacg aatggaacaa agaagaacaa
    13741 gaaactgtca tagaagacgg attagtggta ttagatgcaa atggaaaccg tctgttagag
    13801 ggcgatagcg tgacagtgat taaagacttg aaagtaaaag gtgcgtcagg tgccattaaa
    13861 caaggaacaa aagtcaagaa catccgttta gtagaaggcg atcataatat cgattgcaag
    13921 gtagaaggat ttggaccgat gaaactgaaa tcggaatttg tgaaaaagaa ttaaagaata
    13981 ttcaaggtct tttcacattc ttttcctact actaatgata aaataaagta aacgaaaagg
    14041 agtgaaacga aaatgtatgg ttatggaatg tatggttttt tagatccgac atttcttttg
    14101 gtcattcttg gattagttat ttccggaatt gcgtcagcgt acgtcaatag tactttccga
    14161 aaatacgatc aagtgagaag caaaaacaat gtgactggta cacaagcagc acaatatata
    14221 ttacaaagtc aacagataaa taatgtcggt gttcaacaaa ttgccggaga tctcacagat
    14281 aactacaatt caggtaataa gatgttgagt ttgtctcaag caactgcaca gtctacttca
    14341 gttgctgcga taggtgtagc agctcatgaa tgcggacatg cggtacaaga tgcttcgggt
    14401 tatgtcccat tgaagattcg tgcagcactt gttccagcag ctaactttgg ttcgatgatt
    14461 tcgttcccct tgattatggt aggtgtattg cttagctgga actctacgtt aatcaatatc
    14521 gggattttcg ctttttcttt agcattactt ttccaattgg tgacattacc agtcgaattt
    14581 aacgcgtctc ggcgagcaat ccaaattttg agtgaaggcg gactactgac ggaagaagaa
    14641 gtaccgatgg caagacacgt attatttgca gcagcactga cttatgttgc agcagcgctt
    14701 tcgacattcc tgcagctgtt gcgcttgatc ttattgttcg gcggcaaccg aagagattaa
    14761 aataaagaag ttgtgaaatc agcgctttga tctgagctaa taccgagagt tagctgattg
    14821 aataccattt atttggaata
//
LOCUS       DAFEEZ010000071        14746 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.074, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000071
VERSION     DAFEEZ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.074"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(555..917)
                     /locus_tag="LP245_002336"
     CDS             complement(555..917)
                     /locus_tag="LP245_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520226.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(991..1371)
                     /locus_tag="LP245_002337"
     CDS             complement(991..1371)
                     /locus_tag="LP245_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBL1520227.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1435..2628
                     /locus_tag="LP245_002338"
     CDS             1435..2628
                     /locus_tag="LP245_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL1520228.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2705..3289)
                     /locus_tag="LP245_002339"
     CDS             complement(2705..3289)
                     /locus_tag="LP245_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1520229.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3490..4488
                     /locus_tag="LP245_002340"
     CDS             3490..4488
                     /locus_tag="LP245_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL1520230.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4600..5109
                     /locus_tag="LP245_002341"
     CDS             4600..5109
                     /locus_tag="LP245_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBL1520231.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(5139..5798)
                     /locus_tag="LP245_002342"
     CDS             complement(5139..5798)
                     /locus_tag="LP245_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBL1520232.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5800..6564)
                     /locus_tag="LP245_002343"
     CDS             complement(5800..6564)
                     /locus_tag="LP245_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBL1520233.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6572..7249)
                     /locus_tag="LP245_002344"
     CDS             complement(6572..7249)
                     /locus_tag="LP245_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBL1520234.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7286..8671)
                     /locus_tag="LP245_002345"
     CDS             complement(7286..8671)
                     /locus_tag="LP245_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBL1520235.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8881..8965)
                     /gene="ffs"
                     /locus_tag="LP245_002346"
     ncRNA           complement(8881..8965)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="LP245_002346"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8988..9503)
                     /gene="tadA"
                     /locus_tag="LP245_002347"
     CDS             complement(8988..9503)
                     /gene="tadA"
                     /locus_tag="LP245_002347"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBL1520236.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9610..10467
                     /locus_tag="LP245_002348"
     CDS             9610..10467
                     /locus_tag="LP245_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1520237.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10548..10883)
                     /locus_tag="LP245_002349"
     CDS             complement(10548..10883)
                     /locus_tag="LP245_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520238.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10950..12320)
                     /locus_tag="LP245_002350"
     CDS             complement(10950..12320)
                     /locus_tag="LP245_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBL1520239.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12398..12934)
                     /locus_tag="LP245_002351"
     CDS             complement(12398..12934)
                     /locus_tag="LP245_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL1520240.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13243..14724
                     /locus_tag="LP245_002352"
     CDS             13243..14724
                     /locus_tag="LP245_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1520241.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         4527 a         2929 c         2395 g         4895 t
ORIGIN      
        1 ttcatcggga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag cgattgtcaa ctctttttta aaagtttttt tcgatttcgt ttttcgaaat
      121 ctttcagcaa ctcatttatc ataacttatc gtttgttatt tgtcaagaac ttttttgaag
      181 tttttttcga tagaatcaag cttcgcaagt ggttcttttt taacgactca gttatcttat
      241 catgtcgtta gtaacatgtc aataactatt ttttaaattt tttagaaatg tgatataaca
      301 tccacttcag aatcaacgct gttaaattta tcatgtattt cttccttggt caactataaa
      361 ttaagcatta ctttgtgaaa tgatttttcg atcaattatt attattcgtt atacaaccgt
      421 tttcaacata ttttgaaaat aaaatgcact aaaaaactat ctttagcaga acatttcatt
      481 gtattttttg gaccaaacaa taaaaaaaga agtttgaaaa aaattcaaac ttctttgttc
      541 gcttaatctg tattttagaa gaaaggcact ccctctactt cgtaagttcc aagaacagag
      601 cgcatttgac ctggttcttc ccaaatatat ccttcgccta attcttctct ttgattcttt
      661 tgttcagttt caaagacaaa caacggaaca ttttcctctt taatatgtgt atttgtcaat
      721 tccatcaaac taatcttgct aacatcgata tgaactattt cttttaagaa attaagtata
      781 ttcgctaaac cagtctttcc ttcagaaagt tccgctaacg caaattccaa cttgtcatca
      841 attgaatgga ccaaaaattt tttagtacca tcctccaaat gcaacataat tgtaccagca
      901 actcttttgc ttgccaaaat ttccacctcg atcaacttgt tctatggctt acataaaaat
      961 tctagcacat tttcagaaaa aatacacttt ttatttctta ttttctttcc gttctagttc
     1021 agataatgct tcttctatcc aaataggtaa ctgctccgca atagtggtaa atccgatctt
     1081 acgattttta ttcgtgaaat acctttttct gcgatatgga acagctggat ttgttttttc
     1141 taacgttctt aaagataaac tgattttttt ggaatattca tcaatgtcga tgatctgaac
     1201 tgttactggc tgtccgactt ttaacaatga atggatattt ttcgtataac cggattgtac
     1261 ttctgaaaca tgaataagtc cttgcgtctc gttatcaaga gaaacgaatg cgccataagg
     1321 ctgtatccct gtcacttttc cttcaattat ttgtccaatt ttataagtca tctacttccc
     1381 tctcttcgca tttatcatta tactgtaaat agctcaaaaa aagaagcgac gaaaatgact
     1441 ggaggtctta agatgatcga atttgataaa cagatttcaa gaaaagatac agaaagtgta
     1501 aaatgggacg caattgctga gacatatcaa atggatgact tacttccttt gtgggtagca
     1561 gatatggact tcttgtctcc cggtggggta gctaaagcgt ttagtgaata catcaaacat
     1621 ggaatctttg gttatgccac tctgtctgat aaactatatc aggctatcat tcattgggaa
     1681 cgccaacacc atgctgtgga gttgacgaaa gaaaatatcg tttttacaag tggtgtgtta
     1741 accagtttag ctgcagcagt acaaactttt acaaaaccag gcgattctat tttgattcat
     1801 gacccagttt atcctccatt ttcctctatt atagaaacaa atcaacgtca catcgttcga
     1861 agctctttgc tagaaaaaaa taatcatttc atcatggact tgtctgacat ggagaaaaaa
     1921 atcgaagaaa acaatgtaaa agcaatgatt ttatgcaatc ctcacaatcc tggagggcgt
     1981 gtttggagca aagaagaatt gaaacagtta agcgaattgt gtttaaaaca tcaagtgatt
     2041 ctgtttagtg acgagatcca tcaagattta actttattcg atcatacatt tacttccatg
     2101 ctaacgattg atcctaattt agatgatcta ctagttgctt ttacttccgc aaccaagact
     2161 ttcaatctag ctgcaatcaa aaattcaatg gtatttatca aaaatccaga gatgaaagct
     2221 gattttgaaa aacatttagt gatgaaccaa cagcacgaaa tcaacacttt tggactgatt
     2281 ggaacccaag cggcttatga gacgggtgga gaatggttaa gccaactgat tccttatcta
     2341 gaaaaaaatg ttcaaacagt taatcagttt tttgaacagt atcttccgaa agtgagaata
     2401 atgaaccctg aaggaactta cttaatgtgg ttagatttta ccgcctatat ttcagacgac
     2461 caagaattgg agaacactct tgttcggaaa ggaaaagtcg tattaaatcc tggcatcacg
     2521 tttggtcctt ccggtcatgg gcatatgcgc ttgaatattg cttgtccaga agaaacttta
     2581 ctggaaggac ttaatcgaat caagtatgct ttagagacaa tcgattaaat catttattca
     2641 aaataaaagg acgagacctt actaggtttc gtcctttttc ataattactc cgtaccatac
     2701 caaactattc tgaaatttca attgtttcaa tcactacatc atgtacaggt cggtcttgtg
     2761 gaccacgttg tacatttgcg atttcatcta ctgtgtccat cccttctagt acatgtccaa
     2821 agactgtatg tcggaaatct agccaaggag ttccgccacc tttatacgct tcaatgattt
     2881 ctgatgggaa tccagcacct tctagttgtc caagcatatt agctggcaca tttgtgttat
     2941 ttacaataaa gaattggctt ccgtttgtgt ttggacctga atttgccata gataaagctc
     3001 cgcgaaggtt gaacagttca cgactgaatt catcttcaaa actttcgcca taaatacttt
     3061 cgccacccat tcctgttcca gttggatcgc cgccttggat catgaaatca ggaataacgc
     3121 ggtgaaaaat cacgccatca taataacctt ttttggaaag ttcaatgaaa ttttgaaccg
     3181 tcttcggtgc tagttcaggg aataattgaa cagtaatgtc accacggttt gttttgataa
     3241 cagcttttgg tcctttttca ctttttaaat ctagttgtgg gaatgccata ttgtttcctc
     3301 ctaatatttg catacttcat aataataata acataatacc taacctctcg taaaaatact
     3361 agatttgttt tcttttattt ttcatcacta gatacattct ataacttacc gtttcgattt
     3421 cgaattcaaa catttttgag aagcattctc aattaaattc tgctatagtg tgaaaaggga
     3481 ggaattttta tggaaatcta tgacattaca atcatcggtg caggtcctgt agggatgttt
     3541 gccgcttttt acgcaggaat gcgccaagct aaaacaaaaa tcattgacag tctacctcaa
     3601 cttggtggtc aattagcaac tttgtatccc gaaaaatata tttacgatat tcctgggtat
     3661 ccagcaataa aagcaagtga attaatcgat caattagaaa aacaattaac tacttttaac
     3721 catacattcc atttaaaaga agaagttctc tcgcttactc gtgaagacga agttatcgag
     3781 attactacaa ataaaggcat ccattattcc aaagcagtca ttttagcttt aggaaatggt
     3841 tcattccagc caagaaaatt gaatttagat aatgctgaat catttgaaaa ccacggattg
     3901 gattatttcg tgaatgattt gatgaagtat gctggaaaaa aagtcgctat tgctggaggt
     3961 ggtgattctg ctatcgattg gacgttgatg ttagagccta ttgcaagcga agtttacttg
     4021 attcatcgtc gcccggaatt tcgtgcgcac gaacatagtg tatcacgctt gaaatcttca
     4081 tctgtcaact tgcttactcc ctatctcatc gatggattat caggcaataa tggggaactg
     4141 acagatatcc ggttaaaaaa agtgaaaagt gacgagacga ttgatttgat gattgattct
     4201 ctgatcgtca attatggatt ctcttctaat ttagaacatc tttcttcttg gggacttgat
     4261 agtaccagaa atgccattac tgtaaaatca gatatgtcta cttctattcc aggcgtttat
     4321 gcagctggtg acatctgtac ctatgaagga aaagtgaaac tgattgctac tgggctcggt
     4381 gaagcaccta ctgcagtgaa caacgcttta cactatatta atccaaagga acgaactcag
     4441 cctggtcaca gcacaagctt atacgataaa aatcttcgtc ctagttgatt ttttatatct
     4501 ctttgcattt caagttaaac ccgaaagcag tttcttgcat ttttttcatg ttccgttaac
     4561 atgaaataga gaaagaaaaa ataaaggggg agcaataata tggtcgtcaa aactgagact
     4621 ttagaagaaa aggcaagaga actattgaag gaacgtggcg taactgtaga agatatcgca
     4681 caacttgtca tgtttttaca aaaagactat atttctgatt tgactttggc ggattgtact
     4741 gaaagtgtca acagcgtgct aacaaagcgt gaagtacata acgccattat cactggaatc
     4801 caattagata tattagcaga aaagaaaaaa ttgatgagtc cgttgcaaca tattatcgaa
     4861 gatgacgaag gcctttacgg tatcgatgag atcctagcct tgtcaatcgt gaatgtttac
     4921 ggtacgatcg gctttacgaa ttatggttat atcgacaagg tgaaacctgg tattttaaaa
     4981 gaactaaaca gccacgatgg cgttcatgtc cataccttct tagatgatat cgtcggagcg
     5041 atcgccgctg ctgctgccag tcgattagca cacaaagaac cagaaaaaag aagtcgcctt
     5101 actcaataat tcaacaaaaa aagaaagaaa acgtctattt agacgagttc tttctttttt
     5161 gtttgtttca agctattttt tcctaagaaa agaaaaacag caaaaaataa ttctaataat
     5221 acaaaaaata agataaagct atgcatgaaa aattcttctg gaagtacatt gatgattgga
     5281 tcagtaacgg gatcgaataa ccagtcatcg ttgttgaaaa acgtttcatg aaaaaggata
     5341 aaaaagcgat caaatcctat catcatgaaa aaaccgaaaa caactggcag taacatgccg
     5401 atttgaaacg gacgaatcaa ccgccaaagc cgatcattct tttgcaaata tttgataaac
     5461 aaaatactcg ggatcaaagt gatgaaaaac acagcataat ccactaaaaa caaaattttc
     5521 acttcataaa agtgatgggc tccgctagca gaaactggga aatctggcaa gctgaggatg
     5581 gttttgaagg gattattgag ataattcatt aggtgatcaa aatttttcag taacgtctct
     5641 tgatctaaag aagtataatc caaaatttgc aaatgtccga tatcaaatac gtatagtggt
     5701 cgaaagttga tcgtcacacc aactgccaga ctgatcagtg tcagaaatag gctgaacaat
     5761 ccagcatatt ccatccactg ccatctcgaa tttttcatat tagaagctcc attcatccag
     5821 tgattgtttc acataggtag ctgggatagg caacccaggt acatcttctt cttttgtaaa
     5881 acctgataaa acgagcaaag tatctatatt attgcgtatc ccagcttgga tatctgtttc
     5941 atagttatct ccaaccatga ttacttcttc tttttgcagc cctaatactt caacggcttt
     6001 atccataatg atggcttctg gttttccgat gtagatcggc ggcgtttggg ttgctgtctc
     6061 tacaaaagag atgactgacc ctgctccagg aagaaggccg cgttcagtag gtatattctt
     6121 atctgggttc gttccaatga aagtagcacc tttttgaata gcaagtgttg ctttaactac
     6181 tttttcatag gtcagataat tatctaagcc taccactaca tagtcaggag cctcttcttc
     6241 ccatgtaaat ccggcagcta aaatcaagtc aatcaatcct gcttctccga taacatagac
     6301 ttttttccct tttccatctg ctttcataaa atcgattgtt gccaaagtag ctgtgtagac
     6361 tgtctctgga gctacatgaa tgtcaaactc atctgctaga cgattagcta ctgtttctgg
     6421 tgacttagtc gtgttattgg taacaaacaa gaaaggtaat tttctttttt gcaattcttc
     6481 cacaaatcgt ttaccggccg gtatgggttg tgtcccacga taaatcgttc cgtctaaatc
     6541 aattaaatat cctttatagt ccattcatcc actactcttc cctttttctg atcgtaaatg
     6601 ctgtttttgt tttttctact tgtttaggtt gttcttgttt ttttactttt tcagaggttt
     6661 ttgctgactc tgtttttcga tttttaataa ccggtttttt gcgattagat gcgactggtc
     6721 cttttttctc atcgatatac gcacgattat ggtttttttt cttttttcgg cgctgagttg
     6781 tcttttcttt tttaccgccg attctctcga tgacaaaata cgcacaacca aaattgcaat
     6841 attcgtaaag atagtcttcc aaggaatcga ttcgctgatc tggatgcgcc cgtcgattat
     6901 ccgcttggaa aaatcctttt aggcgtagtt gttcataacc ccaatctcct acgatataat
     6961 catatcgggc tagtacatca ctgtaacgtt ctccaagctt ttctgcatta aatccttcac
     7021 gataatcgga cacaagccga taatgtcttt cacctatcaa aaaattactg tcatctaaca
     7081 gtgtcactag ctcgcctttg actttttctg ctttaggctc ctcaacgatt tcttccaaag
     7141 cagctgtcag ttcttcggtg actgttgttt cctgttcagc tgatgatttt ttcttagcaa
     7201 tttctgtttt atgctcaacg ttctgctgtt cattttgttt tgcagacatg cgttcaccac
     7261 ctatcttttt tattatacct tgtttttatt tgattgggta gtgagctttc aagtaatctc
     7321 ctaccacact tcggataaat tcagggaaca aaaattcatt ttttccagca atctcaatcg
     7381 ttggaaaaaa tggaacaaac atcaaatgat ctacggtagt aaaagtataa tttttattca
     7441 gatcgattgg cttgttcttc caaaagactt gatggttaat agaatcatat gtgattccat
     7501 tatagaccat ctgcccaaaa atcttaccgc gaaatcccat tcccttcata ggatagttac
     7561 gtaaaaagtt acgatttttt tctatttcta aaactaagcg gatcagatca tttccaccca
     7621 atgtgacatt taacaagtgc atcggatgcg gcaacgcagt gtgaagctga tcctgattga
     7681 cccgcccttt tggaatttca gttaaaaaca gaccactgtt taatattgct gcttccgtct
     7741 ttcctcgttc tttcaccgcc tcaaaggcta cttggataaa cgaatgctca ttgaagatat
     7801 ctagactcag agaaaatggc aaatctgcta cttctttttc ttttaataat tcatgcccac
     7861 gttctagata actatttatt tcttgttcat cttctgtaaa agctgtcatt gtttcggtag
     7921 ggatggcttt ggctgaatgc ttaaggattt ttttctcttc atcgatggtt aaatggactt
     7981 caccgacata ctgcccgtac tttccagcgg ctgctatttg gacatcattg attacgtgac
     8041 cttctctgaa taaatgatgg gtgtgcgatc ctaaaataac atcaattgct ggtatttctt
     8101 ttgcaatttg gaaatcatcc tgaatcccga gatgactcat caaaactaaa acatccactt
     8161 gtgaacgtaa atcttcgact aattctggca aaatatcata aggattccgt atgtcccagc
     8221 cattcggatt ataagtaagc ggaaatggag cagtaaatgc aattagtccg attttcgtct
     8281 ggtgtttcgt tgtaatgatt ttatatggtt tcgtccatgc cggtggctgg agcgtatttt
     8341 tatcgaataa gttatccagg atgatatcaa actcagcatg atcgtataaa tgattcaact
     8401 cttctttgga atttcctacg ccttcattgt ttcctatcgt cgctgcatca taaccaactt
     8461 cattcatcag caagatattt tcctgtccat tcgttgcttc tgacaatgga tgccaacgat
     8521 ccacaaaatc acctagatct actgcaatcg ttgtcgtttt ttctttcttt tcgttttctc
     8581 gtttacgttg atccaaaaac cttctgatcc ttggccaatt ttctaaatga gaatgcagat
     8641 cattcgtatg taaaatcact attttttcca tgtaccctct cgcctctctt tatctttatc
     8701 ataccatagg cagctttttc ttccattgaa acaagctcta tttcagagtt tttcctgcct
     8761 tgaagcaaat tgtataagta caatattcga taaatcagtc tggctaaaaa atcaggaaca
     8821 ttcattttta cagtactata aaaataaaaa aaacagaccc gaaagtctgt tgtcgtttca
     8881 ttataatcag acacatggcg gaacctgctt agtgctgctt ccttccagac ctgacacgct
     8941 tcacaagccc accattgtcc tagcctttcg gcaaagaata gtatacctta tttttcattc
     9001 gttgaccagt ctttttttaa tttctttttt cgctggcgga gctttcggaa aaagtcagtc
     9061 aaaatcatcc cacattcgtc ttctaaaatg ccaccttcta catatgcttg gtggttaaac
     9121 cgctcgtcct ccaaaagatt catcaaggta ccggctgttc cgccttttgg atcatacgcg
     9181 ccgaaataaa cttctgctac acgagacaaa atcatcgcgc cgctgcacat aggacaaggc
     9241 tctaaggtaa caaaaagtgc agcatcttcc aagcgccagc ttcccacttt ttcacaggct
     9301 tccttgattg caagcatttc tgcatgtgta gtagcatctt gcgtggtttc tctaaggtta
     9361 tatcctcttc caatcacttt tccatccaat acaaccactg ctccaatcgg aacttcatga
     9421 agcatttctg ctttctttgc ttctgccaat gcaaggcgca tccatttttc tttttctact
     9481 gcatcaagat ttgtatttac caattaccct tccctgcctt tgttttttct tgttttactt
     9541 tagcatatga taaaaaggct gtaactaact tttttttcta tggtaaaata aatacaagag
     9601 gtgaacaaga tgaaaatgga taaattactt gctctttacc cacaagcaca gaaaaaaaac
     9661 tctccagcat cagaagcgga tatcctttct tttgcaattg atgatgcttt tatctggatc
     9721 aaacaagatt cattatctca acaagaaacc agccttttga aagcgttatt ccctgtaatc
     9781 aacgatcaaa aaaaacaccc atggtatcgc tatcttttta aagatgcttc ttgtgttcaa
     9841 gaaaaaagct ttcgtttgat ccagcttcac gtcgaatcaa aaggagaatt cttaaaaaaa
     9901 gaatggcaag atactatttt ggaattattt cgctattctg ctgatttctt tttttataca
     9961 gacacagatg cgctcttagt cgaacaaata aaccgtgatt atcttgatgc tactgaaatc
    10021 aacggtattt ttctatcttt agatgctgat tttgatacga caacgtctgt attcgttggt
    10081 tctttccatt cacctggcac cgacctcgtc cctttgtttg ctgaagaaag aaaaattttt
    10141 ttaacagagc aaaacaatct ttatactcac agccgtactt tttctatgca agatgtggct
    10201 ttacattact atacaaaaga tactgtaaaa gatagtaagt tgatcaaaag ttacatagaa
    10261 ctgatcaaac aaaatgaaat ggaagtgatc attcaagaat tatggaatga attaggcaat
    10321 gtcagctctg ctgcaaaaac actgtttctt catcgtaata ctctaaaata tcgaatcgaa
    10381 aaatttcaag aacagtctgg tttcaatcta aaaaaagcca acgatttact gttttgctat
    10441 cttttattgc ttcatgaaca taattaaaga tagattaaag gggttgtgac aataattttg
    10501 tcacaacccc ttatttcgaa tgaatagtgt tcaaaagcta gtttctctta catcattttt
    10561 tcaacaaaat gcattagccg gtcttttaca tcttcggttg aatctttgat tgaatcacca
    10621 taaacagaga ttttcttttt tcctgatttg atttttgcta acattcccat caaagaatcc
    10681 aagtcactat ctgaaagacc atctacgatt tctagtaatt tttcatttcc atcaaatttg
    10741 tcatagacga atttttttac tttcgtccga gtagtcatat gatggatctt ttccattact
    10801 tttcccgata caacgactgc tgtcgctaca ctggcagcgg ctgctacgct taatccgatt
    10861 gttacttttg ttgatgtttt cataagtatc agctcctttt tatctatctc catcatagca
    10921 tagacaaaaa aataaacgaa ctaatccact cagtgaaatc tcaatccttt agggaaaaag
    10981 ttctttactg ttccttttac ttgtttccca aatccgacag gtatcttatc taatactagc
    11041 aaaacccatc cttgattccc atcacgttga aatgtttctc ctgctgtgta agattgccat
    11101 tccttttgag tgatcggcaa gcaaggtata ttctctatct tttttgtagc aagcgctaat
    11161 gcatagctag gttcaaatcg attctttttg aaatctccta aatgcaaacc tgtacgtacg
    11221 acttttaaac catcgagaga aggggctaac tcaggaactt cccaaagatg gtcgttgaac
    11281 actaaaagtc ttccagtagc ttcataatga aaatcatttg aaaactccgt ccagagtttt
    11341 tcctgctctt ttgtcatttg cactttactt ttttttcgtg tcttcttttc tttatgcatc
    11401 tgattttgtc catgaaaagt cagctttgca acaaaatgtc cttcaccctg atctttatga
    11461 ggccatatac gtattgtttt ttccaaacca gctacgcttc cccattcaga acgtcctgaa
    11521 ctaacggatt gagtcaaagg aatctcctca atcgttactg gataattttc tacaagccag
    11581 ctaatgatct cttcattttc ttctggtgca aacgtacaag tcgaataaat cagttgtcct
    11641 ttatttttta gcatttttat tgctgaagac aaaatctctt gctgacgttt ttgacagtat
    11701 agcggagatt cttctgtcca ctcttttatt gcatttggat cttttcggaa cattccttct
    11761 cctgaacaag gagcatcaac cacgatccga tcaaaaaagc ccgaaaaatg agggacaagt
    11821 tctgcgggtg catgatttgt cactattgcg ttcgaaactc cccatcgttc tatattttct
    11881 gataaaatct tcgcacgttt cggaaagatc tcattcgtca ctaataaccc tttccccttc
    11941 atttgagcag ctaattgggt tgatttacca ccgggagccg cacacaaatc caaaactttt
    12001 tcaccgggtt ttgctgcagc agctgttcca acgatcattg cacttggttc ttggctatat
    12061 tcatacccag cttgatggag gaaagacttt ccattgacag tgccaagaaa tccctcattg
    12121 ctgtagggag cgggttgtaa ttcttcgcta tggtaagttt ggaccatgtc caatcctgcc
    12181 ggttttagtg gattccaccg aaatcctttt ttcacgcttc cttgttcaag cgcagaaaaa
    12241 aaatcggatg cttcttcgcc taaaagaaga cgatattttt tgataaattg ctgtggtaac
    12301 gttgtcgctt cctccttcat tccaatgttt cgttagacat tttacaatct tttttacgaa
    12361 aaataaaggt ggctgatcta ctttttcatg ttgctgccta aggtgactgt tcctttaaga
    12421 tattttccaa gtattcatcc gtcacctcgt ttttatccca aacagcgttc atcatttcaa
    12481 gaaaatcttg agaagaatca tctgagcgca aacttcccaa tgcattaagc cataccaatt
    12541 caagcgactt ttcttctttg atcttcgtgt gacctttgac atatgagaaa aatggccgct
    12601 taaatagcga atccatgtct aaatcagatt ttgcaatgat ttcacgaata ctttcatgga
    12661 tagaaaaaaa atctttcaat aagtagacaa tgcttaaaac atcatcggaa ctgcattcag
    12721 ctaagtagtt ttcaaaataa acagtgattt cttctaatat cttctctttt aacccgctga
    12781 ttgatttgaa atgtgtataa atcgggtatg tagaacaacc gcagaactct gctaactctc
    12841 ttgcagtaat tgacttcatt ccatattctt ccacgtatac catacttttg aacagcaaat
    12901 attctttact ataatttgtt actctcccca tcattcttac ctccgtctct tttcatctac
    12961 ccataaataa ataacataaa taattctaaa aatattattg ataattatca aaacatattt
    13021 agttatatcc attaaaaatc aatttttccg ccttaaaaac aagaatatct tgacaaaata
    13081 ccctaggaaa taaacaatag aataaacaag gtaacaaaaa aattaaataa cgttatataa
    13141 aaaagaaggc gacactctgt gagaataaca cagactgaaa tgactttcca ctcacagttt
    13201 ttgtctaact atatacaaaa acagaataaa aaggaggtat ttatgctaat tgaagcaaga
    13261 aaaaaagagt tacttgttct acaaatggtc attcaaaaaa ataattgttc tttacaagaa
    13321 ttatccaatg acttacatat tccaaaacgg acaatcaaag aactgatccg aaaaataaat
    13381 gtatcactca agcaattttt attgattgat gaatttattt attctaatca taaaggagag
    13441 atccaaacca aagaaaccga tcaaactaaa aagttagctg ttttttctaa gttaaaatta
    13501 tgctacctaa aagaatccaa tcgttttaac tatttgatgt tactaatcaa ttatccacaa
    13561 actgctgtac caaaaaaata tttacttgaa caactttata tatcgccctc ctatctcgaa
    13621 aaactgacaa aacagctcaa tcattcctta aaaaaattcc atttacggat cctatctgta
    13681 aaaaattgct gtactcttga aggaaatgag ttatctatcc gtctctatct ttactttttt
    13741 ctttcagata catttggagg taacgattgg ccattttcct cacttgaatt aaatgcacta
    13801 aaaatgaaca gtacagatga gcaaatagaa aaaatttcaa aacaagaaaa aaatatctac
    13861 ttgctgttaa ctttattcat attacgaaac aaacaacagg catattttcc aaaaacttct
    13921 tctgaaatca ctgaattgat ggacttattg cagcatacac atgattattc agaatacttt
    13981 acttcttttt cagtgagtcg cccttgtgaa gagacagaaa cagagagagc ctactttaat
    14041 tattttttct attgtttttt tccaaatcaa atctcttttc gacaaaaaca ggagattggt
    14101 tttttatttt ccacaagcaa aaaccttatt tgtcgacaag tcggtcaatt gatgacttac
    14161 ttaactcaac agtttcctct caaccattta gaaaataaaa taccaattta tttttatttt
    14221 cttgtgttgg cagttgtttt tttcgaactg ttgggtgaat ccagcagtag tttttctaca
    14281 ctttgctttc cagaagccac gtccaatcat tctagttctt ttatacagga aaagaaatta
    14341 agagaaaaaa tcgatacaat tttttcaaaa aatggggaaa gaaaccaaat cagtcaatac
    14401 cttagtcaat tgatccaaca cttactacaa acagaaacga aagagcagtt actcatccat
    14461 ttgcagataa ccaaacagtt tacaggaaat tatcatcttc aaagccattt gcagcagtta
    14521 tttcgcaaag atgctgttaa aattaccgca tattcagaac atgctgattt gatcattaca
    14581 gatcagcatg agaaaatttc agatgaaacg gagactttct atctggatac aacgcacaat
    14641 acagtgttat ttggcaagtt aataaaagcg gttcatgaac tgtatatgaa aaaaggttat
    14701 gagaacaaaa caaagaggat gtgacaaaat tcttgtcaca tcctct
//
LOCUS       DAFEEZ010000072        14555 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000072
VERSION     DAFEEZ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14555
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.075"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            61..624
                     /locus_tag="LP245_002353"
                     /pseudo
     CDS             61..624
                     /locus_tag="LP245_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            630..1046
                     /locus_tag="LP245_002354"
     CDS             630..1046
                     /locus_tag="LP245_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520242.1"
                     /translation="MEFREGAFDFQTSQQNRKFIPEDFQNLQLENMRLEDLFRLADDD
                     KYRFEVLKIKKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNR
                     NSTDVVMITDIYVEDEVIIKYMKPVIKLVNKNKGNG"
     gene            1152..1415
                     /locus_tag="LP245_002355"
     CDS             1152..1415
                     /locus_tag="LP245_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL1520243.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDLKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            1415..1687
                     /locus_tag="LP245_002356"
     CDS             1415..1687
                     /locus_tag="LP245_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBL1520244.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTYEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            1764..2093
                     /locus_tag="LP245_002357"
     CDS             1764..2093
                     /locus_tag="LP245_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1520245.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            2083..2370
                     /locus_tag="LP245_002358"
     CDS             2083..2370
                     /locus_tag="LP245_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL1520246.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            2656..3513
                     /locus_tag="LP245_002359"
     CDS             2656..3513
                     /locus_tag="LP245_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL1520247.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            3514..4062
                     /locus_tag="LP245_002360"
     CDS             3514..4062
                     /locus_tag="LP245_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520248.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(4359..5306)
                     /locus_tag="LP245_002361"
     CDS             complement(4359..5306)
                     /locus_tag="LP245_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HBL1520249.1"
                     /translation="MHLEFSDYESLLVKICEDYYLEDINISEISKKYGITRYKALKYI
                     EDAREKQLVSISINSPYARNYELEEIFKNYFKTNIYILKSSEDLSQHDLLFSKFAADY
                     IQELIKKANVVALSWGDTVYKVIDQFKMGAREELIFTQFIGEIGKYNSLAGSTRLVQK
                     AAERYESSYLTLSIPLYVINETARELMALEPSLANTLATASHADMLISGIGTLSSIDS
                     VEPWNKHRKILFPSMTDTVGFLYGRPFNINGEFIKASEDKTFGLSLKEIFDIPKRIGI
                     CKSKFKAESCLGALNGNFFTDLFLDEKTAWKILSLIKKE"
     gene            5494..6681
                     /locus_tag="LP245_002362"
     CDS             5494..6681
                     /locus_tag="LP245_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HBL1520250.1"
                     /translation="MLDEVLEIHKKNVGVLRMETTEAVQDDQDLAKMYTPGVAELSLM
                     IEKNHALARELTISGKLVAVITDGSAVLGLGNVGNQAGLPIVEGKALLYKNLAGVNAI
                     PLAIEQKSVDEIVQTIVNLQNSFAGIHLEDIAAPKCFEIEEKLQEKLSIPVYHDDQEG
                     TAIVVLAGLINAAKIQRKTLTELRVLINGMGASGVATARLLIAAGIKNLTLVDKQGRL
                     KKQDSTLNKYQRELLDHIHDTNNNASVLEDAIVGQDVFIGLSIGNVLTPEMIGKMNDN
                     PIIFALANPVPEITPDLAKESGAKLIATGSSKYPNQVNNILVFPGLFKGLLLSKANKV
                     DLSLQLEVAKQLAAKVAEPTVEKFIPNVFDEGVANVVSQAVLDYLQKLKENEDNIHAE
                     NIK"
     gene            6662..7966
                     /locus_tag="LP245_002363"
     CDS             6662..7966
                     /locus_tag="LP245_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBL1520251.1"
                     /translation="MLKTLNRIKIGFIPLSLYIILVLAYLAMTISNIVPENDMLVSLG
                     IMTVFAYLLEEIGKTIPILKDLGGKVLVVTFLPAFLVYKHWLPQSTVTVVSDFMNNNN
                     FLMFFITLLVVGSIASMNRQTLVKATSRIIIILILCDVIGSLIGTGVGILLGLSAWNA
                     YFFIVAPIMAGGVGEGAMPLSIGYAAILSGMGQNDIFGKILPCVMLGSLVAVLLSGML
                     KKIGEKYPQLNGQGNLIDGDDEHLENLKGSAKPVNIEKTLLAGVVAITIYFVAVYVEH
                     LLKSLLGFSIPSPVILLVSLMGAKMLGFIPKNIEEGGNSLYGFTVRGITPPLLFGVGV
                     AKTDWLELIEVFKNPATIVTIIVTVVAIVATAFIAAKFLKMYPVDTAIAVSCCSGQGG
                     TGALAILAAGDRMELMPFAQVAVRLGGAMTVTFAIFLMGLLS"
     gene            7992..9005
                     /gene="citC"
                     /locus_tag="LP245_002364"
     CDS             7992..9005
                     /gene="citC"
                     /locus_tag="LP245_002364"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HBL1520252.1"
                     /translation="MFDQTDIQRLFLKNNYIKDQWENLLLDSGIQKKQIEDFQHLDQT
                     LGIYHKEKLVGTVSYQNNVIKYIAVSEKYKDGGHTFNVLVSAIIQAMSQQEIFHYIVF
                     TKPRYQKSFNFLGFETIVSTPKIAVLEMGDSSIKQYLERIPKVNGEKKAAIVMNANPF
                     TEGHYYLVKQAANNNDWVYVFVLEKEQNLFSTKDRLKLVQQGLQKLKNVIVLSGGEYI
                     ISPATFPTYFLREDDEIAKEQMVVDATLFKERIATYLDISARYVGEEPLSPMTRSYND
                     ILETILPPEIKVHVLARKKTEQHQVISASQVRKAYLAGQLEKIKYMVPETTYQYLKNK
                     RER"
     gene            9009..9302
                     /gene="citD"
                     /locus_tag="LP245_002365"
     CDS             9009..9302
                     /gene="citD"
                     /locus_tag="LP245_002365"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HBL1520253.1"
                     /translation="MEINKSAIAGTLESSDVQIMISPNTEGIEIDLDSQVIEQFGKQI
                     KKVIYDTLAVYQIKNVKLKVVDKGALDCVIVARLKTAIHRSLGIQHQETPWEV"
     gene            9307..10212
                     /gene="citE"
                     /locus_tag="LP245_002366"
     CDS             9307..10212
                     /gene="citE"
                     /locus_tag="LP245_002366"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HBL1520254.1"
                     /translation="MMKERLRRTMMFVPGNNPAMIKDAGIYGADSIMFDLEDAVSMAE
                     KDSARMLVAEALKTVDYGDTELIVRINDLHSEFGRADIFAMVKAGAHVLRLPKTETSE
                     DITEVEKVIIEAENYHNVPIGRTLMMAAIEGASGVLNAPAIAKASDRLIGIAIGAEDY
                     VTNMKTKRYPDGNELFFARSMIVHAARAAGISAFDTVYSDVDDMEGFLNEVRLIHQLG
                     FDGKSCINPRQIPVVNTVYQPSIKEIKRSLDIISAIEEAKEKGSGVISLNGKMIDKPI
                     VERAQRTLMLAKASRLIDEEGNIHA"
     gene            10205..11764
                     /gene="citF"
                     /locus_tag="LP245_002367"
     CDS             10205..11764
                     /gene="citF"
                     /locus_tag="LP245_002367"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HBL1520255.1"
                     /translation="MHNKQRRSIPSSVLTKYKKEFQSVSLSPQTIQRCAPKVTTVTNQ
                     TNKLMHSIKEAIEKSGLKDGMTISFHHHLREGDFVFNQVMAVIREMGIKELTLAPSSL
                     TNTMNEVVIECIKDGTVTHITSSGMRGSLGEFISHGGMDNPVILRSHGNRPRAIESGE
                     LKIDVAFLGVPTSDDYGNANATVGKSVFGSLGYAKVDAQYADKVILLTDHLVPYPNTP
                     ISIPQTQVDYVVEVEAIGDPNKIGAGATRFTKNPKELKIAEMVKDVIVHSPYFKDGFS
                     FQTGTGGAALAVTRYLASEMEEKQIKASFALGGITKPTVDLLEKGLVEKVLDVQDFDK
                     GAAEGMARLENQQEIDASFYADPSNKGAVVNQLDVAILSALEIDTNFNVNVMTGSDGV
                     LRGAIGGHQDAATAKLTIISAPLVRGRIPTVVNDVTTLITPGKSIDVLVTEVGVAINP
                     QRKDLIAIFERIPQIPVFTIEELQQKAEKIVGIPEPLQFTDRIVAYVEYRDGSILDVV
                     RQVKEFEEERS"
     gene            11761..12318
                     /gene="citX"
                     /locus_tag="LP245_002368"
     CDS             11761..12318
                     /gene="citX"
                     /locus_tag="LP245_002368"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HBL1520256.1"
                     /translation="MMFDTGEIQEIEDILIHKEQRANLQSNLLSKYSNSSLMVFTLNI
                     PGPIKNNPMIEQVFRQGQQSIQQMFLKKKVEMTYTKEINLPSGLDWYVIVTEAPLNLK
                     KWLVTLEEQDALGRLFDLDVLFKKGEQITIVSRQALNHGERPCFICGKSAKVCARNRT
                     HTVKEMQKKIEQIVADSLKGALKHA"
     gene            12311..13174
                     /gene="citG"
                     /locus_tag="LP245_002369"
     CDS             12311..13174
                     /gene="citG"
                     /locus_tag="LP245_002369"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HBL1520257.1"
                     /translation="MHDNIQKIAQEAQLAMLYEVTCINKPGLVDPVDPGSHQDMDIFT
                     FLQSSVVLTPYFEEFIQTGLDRQHQPIEETFMAIRQIGLEAETAMFSVTNGINTHKGA
                     IFSLGIFLAICGRLTIWKVPCKKSFFQKEIQKMTKNLLNDFGKIDQTKPKAWTWGEYL
                     FVNHGLTGIRGEAKRGYPCVFDRGLPYYQAYQGSQQDKMIDTLLFLSMEVEDTNLIKR
                     SNNRHVFEEYQLLIRPYFELGGVKTIQGKKYLDYLNQQFKKKNWSIGGSADLLILTIF
                     LDKIMDKGWLC"
     gene            13408..13817
                     /gene="tnpA"
                     /locus_tag="LP245_002370"
                     /pseudo
     CDS             13408..13817
                     /gene="tnpA"
                     /locus_tag="LP245_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
BASE COUNT         5188 a         2189 c         2868 g         4310 t
ORIGIN      
        1 ttttcttcta gtctacacac cttaattttt ctgtctagtt aattgtagcc tatccataga
       61 ataaatgttt gtcatactac gatttatcgt tgggtgcaag agtacagcaa agtcctctat
      121 tatctttgga agaagaaaaa tagacaatcc ttctattcat ggaaaatgga cgaaacctat
      181 atcaaaatta agggacgttg gcattatctt tatcgtgcaa ttgatgcgga cggcttaacc
      241 ttagatatct ggttacgaaa gaaacgggat acgcaagcag cctatgcttt cttaaaacga
      301 ctccataaac agtttggtga gccgaaagca attgtgaccg ataaagcacc ttctcttggc
      361 tccgccttta gaaagttaca gagtgtgggt ttatatacta agacagagca ccgaactgtg
      421 aagtatctta acaatttaat agaacaagac catcgaccta ttaaacgacg gaataaattt
      481 tatcaaagtc tccgtacagc ctcttccacg attaagggca tggagaccat tcgaggaata
      541 tataaaaaga accgaagaaa tggaacgctc ttcagctttt cggtgtctac tgaaatcaag
      601 gtattaatgg gaataacagc ctaagatatt tggagttcag agagggcgcg tttgattttc
      661 aaacttcgca acagaaccga aaatttatac cggaagattt tcaaaactta cagttagaaa
      721 acatgcgttt agaagattta tttagattag cagatgatga taagtataga tttgaagttt
      781 tgaaaattaa aaagaatgaa ctattgaata agttatatcc tgagaatgcg ataaaagcac
      841 attttggtga tgctaatcat atgtatagtt ggttcattcc taaaagattt agagggaaaa
      901 tcaatgctgg agatcaagtg aaagtactca atcgaaatag tacagatgtc gtaatgataa
      961 cagatatcta cgtagaagat gaagttataa tcaaatatat gaagcctgtg ataaaacttg
     1021 ttaataaaaa taaaggaaac ggataacact ttacaatgct gttttggtac tccaatttaa
     1081 acaaaacaat cgaatttacg tacttaatta agtacgttag aatggagata taaattagag
     1141 ggggagtaga tatggcaaaa acagtcttaa atcctagctc agcacggaaa aatttttata
     1201 agttgttgaa agatgtaaat gagaatcata cggaaattga aatcattagt gagcgcagtg
     1261 aaaataatgc ggtgcttatt ggtttggatg atttgaaagc aatcaaagaa acgctattac
     1321 ttgagcaaat aggcactttg ggtgttgttc gtaagcgaga aaaagatgat agtggattta
     1381 ctaatgttga tgaaattgat tgggataact tataatgaat aactattctg tgatgattaa
     1441 aaactcggct aaagctgatt taaagaaaat caaacagtct aatttgaaac ctcaatttga
     1501 gaaggttatt cagactttaa aggaagatcc ctatctccct acccaatcat ttgagaagtt
     1561 aaaacctaca tatgaaggta ggtattctag aagattgaat agacaacacc gggttgttta
     1621 taaggtagat gaagatgaac acgtggttga aatttattca gcaaggacgc attacgagtc
     1681 acagtaatta cttgtaaata cattatctcg tggtataatg tatttactaa gtaattacat
     1741 actgttagaa atgagggatt taaatgatta caaaaacaag aaaacaaggc aattcaatca
     1801 tgttgacagt acctaaagat tttaatgttc ctaatggagt cgaagttgaa gcaaagttgg
     1861 tagagaatgg tattctttat gaatttgttg aaccacaaaa agaattttat gattttagcg
     1921 aagatatttt gtctgatata attgcagaag gctacgataa agatgagatt cttgtagaat
     1981 ttaagaatag aaaaaacaaa atgcattctt cctttagaga tattgctgaa gatacactta
     2041 ctaattctaa agtaatgact aaagaggagt tggcaacaga aattggctta tgaaatcgtt
     2101 ccttcaaaac atgtcattaa gtatttaaaa aagctaaaag agaagccatt gaaagaaaaa
     2161 tttttgaatt taatttatga tgaaattgcg attgatccat ataagggtga acaaaaaact
     2221 ggggatttat caggtatttg gtctagtggg ttcaaatatg cgggcacaac atatagagta
     2281 gcttacgaga ttatagaaaa caaggttatt ccagtattgt tatgtggaac gcatgaaaac
     2341 ttttatgaac agttgaaaaa attaatctag tgatttgttg tcgttcttaa gaaggacggc
     2401 ttctttttta tcgaaaatct gattcgtcta catgactaaa gtcgcgagta ttctctgctt
     2461 ctcgataaat taaataacgt cattactttg aggaaagcta taaatcaata tatttcaact
     2521 tttccttatt tatgtactac cttttactta ttaattataa ggtagtacat atatatcttt
     2581 tttttggtag taactaaaaa taaatatgtt ataatagtat caaatgaata ttgctaaaag
     2641 aaaagaggta ggaacgtggt agcgaagaaa tatgtaattg gtaattttaa aggtggcgta
     2701 ggtaaaagta cgtgcgcgca aatgttaggg tttgaatcag cagttaatga aggaaaaaga
     2761 accttgataa ttgacttgga tatgcaagga aatacttctg atgtgatgaa cttaacgcat
     2821 atgaacttca ctaacgaaga aggaggcgga gaaggtgaac cgattgttta cgaaaatact
     2881 gtgactgacg tgttgataaa caatcttcca cctaaagagg ctgtctataa agtaatcaat
     2941 aacctctata tacttccagc agatatgtcc tttgaaatgt atgatgattg gatcaaagac
     3001 caatataatg attcattatc ccaattcaaa tatatgaaag aaaagctaga accattattt
     3061 gatgagtttg acgtcatcta tttagatgtc ccaccttcta tttctgtata tagtaaatcc
     3121 gcgatgtaca ttgcggactg ggcaatcgtc gtcttacaga cccaagtaaa atcgatgaga
     3181 aatgcgatgc aatatcttga gtatatggac ttttttgtga aagaatttga tacaaattta
     3241 tatgttgctg gtgttattcc tttcatgttg gaaagcggtg acgcagtaga tcaggaaatg
     3301 tataaacaag cccaagagat ttatggggaa catttgatta aaaatgttgt actcaaaaat
     3361 gcgcgcttaa aacgatacga cggatcaggt attacgatgg agaagacaaa gaaaggtctc
     3421 ttaaaacaat gggatcgcaa aagccacgaa ttatttatca gtattttgaa agaattggaa
     3481 gaacacgaga attggtatgc ggaggtggag taattggctg acatcaaagg acttgatatt
     3541 tttgggaaca acaaaggact cgccaaaata aaaaaagaag cagaagcaaa gaaaaagcag
     3601 caagcaatta caccatctga aaataagcaa ttagaagtgc accaagttca agaaataaaa
     3661 acttcctcca atgttgaaag acagagtaga ggaagaacaa aaaaagttgg cgcaccaatc
     3721 agaaagtttg ataaggttta ttccaccaag catcctttaa aactgtcgac tttgttaaat
     3781 gcgacttcca gagttttagt agaaaagtat gagactaata tgacaagaga tgaattgctt
     3841 agaaaagctt tagatgagta tattaaacag aatcttacgc aagaagataa gcaagatttg
     3901 tttaatgacg tggtgaaaga actagacttg ttcagagaaa aatatccaat tgttccagaa
     3961 ttagatgacc gtggagaaat aataagaact accagtcaga taaaacaaga taccgaagac
     4021 tcactgcgca aagggtgggg aatgaataat aaagttagat agaaccccct ttttatagca
     4081 taaaaaagat ttagaaggat atatgatcct attgcatgag aagtacaata aaattaataa
     4141 gaagtaacat taacgaaaaa acgtggaaat tattcagtga atacaaagaa attaaatctt
     4201 gaaaagtaat ggagtatggc ttggaaaagt tcaaaaaata tcaagacaag cttctcaaaa
     4261 aaagggattt tgatatccaa taaaaagagt gaatcattgt actgccctcc aaaaaagtag
     4321 taccaaaaat ctaaattttt tggaggattt tacatgactc actctttttt tatcaaagaa
     4381 agtattttcc aagcagtttt ttcatccaaa aataaatctg taaaaaaatt accattcaag
     4441 gcgcctaaac aactctccgc tttgaactta cttttacaaa taccaattcg ttttggaata
     4501 tcgaaaattt cttttaaaga aagaccaaaa gtcttatcct cagatgcttt gatgaattca
     4561 ccattgatat tgaagggtct tccgtaaaga aatccaacag tatccgtcat gcttggaaat
     4621 aggattttac gatgcttgtt ccagggttcg acagaatcaa tagaggataa ggtgccaatt
     4681 ccagaaatta acatatctgc atgcgaagcg gttgctaagg tattagctaa agaaggttct
     4741 agagccatta gttcacgtgc agtttcattg atgacatata aaggaatact gagagtcaaa
     4801 taagaagact cataacgttc agcagctttt tgaactaatc gtgtggagcc agctaaggaa
     4861 ttatattttc cgatttcgcc aatgaattga gtaaaaatta attcttcacg agcacccatt
     4921 ttaaactgat caatcacttt gtaaacggta tctccccaag atagtgcaac cacattggct
     4981 ttcttaatta attcttgaat gtaatcggca gcaaattttg aaaataataa atcgtgttgt
     5041 gataagtctt cactactttt taatatatag atattcgttt taaagtaatt tttgaagatt
     5101 tcttctagct cataattcct agcatacgga gaattaattg aaatactaac taattgtttt
     5161 tcacgtgcat cttcaatata ttttaaagct ttatatctgg tgatcccata ttttttagaa
     5221 atttcactaa tattgatatc ctcgagataa tagtcttcac aaatttttac aaggagtgat
     5281 tcatagtcag agaattccag atgcatagta tagctcctaa ctttttcaaa tagatatttt
     5341 ttctcattat accaaaaaaa ttgaatttag tcttttttta aatttttaaa aataagcatc
     5401 atttttttaa aatttaaaat gaaagggttt ttttatttta aaaaaagtgt taaagtggtt
     5461 ttgtaattaa aaaatgtaaa aaggagtgaa ggtatgcttg atgaagtttt agaaatccat
     5521 aaaaaaaatg taggtgtttt acggatggaa acaacagaag ccgtgcaaga tgatcaagat
     5581 ttagcaaaaa tgtacacccc aggtgtagca gaactaagtt taatgattga gaaaaatcat
     5641 gctttggcaa gagaattaac aattagtggt aaattagtgg ccgttattac agacgggtcg
     5701 gcggtattag gtcttggaaa tgtaggaaac caagctggat taccaatcgt cgaagggaaa
     5761 gcgctgcttt ataaaaattt agcaggtgtc aatgcgattc cattagccat cgaacaaaaa
     5821 tcagtagacg agattgtaca aacaattgtc aatttgcaaa atagttttgc agggatccat
     5881 ttagaagata ttgcagcacc gaagtgtttt gagattgaag aaaaattaca agaaaaactt
     5941 tctattcctg tgtatcatga cgatcaagaa ggaacagcga tagttgtttt agctggattg
     6001 atcaatgctg ctaagatcca aaggaaaaca ttaactgaac ttcgagtttt gatcaacggc
     6061 atgggagcat ctggggttgc aacagctaga ctattaatcg ctgctggtat caaaaatcta
     6121 acattggtgg ataaacaagg gagattaaag aagcaagata gtacattaaa taaatatcaa
     6181 agagagttgt tggatcatat acatgataca aataataatg caagcgtttt ggaagatgca
     6241 atcgttggac aagatgtttt tatcggtctt tcaataggaa atgttttaac gcctgaaatg
     6301 attggaaaaa tgaatgataa tccgattatt tttgctttag ccaatccagt accagagatc
     6361 acacccgatt tagcaaaaga atctggtgca aagctaatcg ctacaggttc ttcgaaatat
     6421 cctaaccaag taaacaatat tttagtattt cccggattgt tcaagggact attactatcg
     6481 aaagcgaata aagtcgatct ttcattacaa cttgaagtag ccaaacaatt agctgctaag
     6541 gtcgcagagc ctacggtaga aaaattcatc cctaatgttt ttgatgaagg agtcgcaaac
     6601 gtcgtttcac aggcagtttt ggattattta caaaaactaa aagaaaacga ggataatata
     6661 catgctgaaa acattaaata gaattaaaat tggttttatt cctttatctc tttatatcat
     6721 tttggtactc gcgtatcttg caatgacgat aagcaatatc gttccagaaa atgatatgtt
     6781 agtttctttg ggtattatga ctgtttttgc ttatttatta gaagaaattg gtaaaactat
     6841 tcctatttta aaagatttag gtggtaaagt attagttgtt acatttttgc ctgcatttct
     6901 agtctataaa cattggctac ctcaaagtac tgtaactgtg gtttctgatt ttatgaataa
     6961 taacaatttc ttgatgttct ttatcacact actagttgtc ggcagtattg cttcaatgaa
     7021 tcggcaaaca ttggttaaag caacttcacg tattatcatt attttaattt tatgcgatgt
     7081 gattggttct ttgataggaa caggtgtggg aatactcctt gggctatctg cttggaatgc
     7141 gtatttcttt atcgttgcgc cgattatggc tggtggtgtt ggggaaggag cgatgccatt
     7201 atcgattggt tatgcagcaa tattatctgg tatgggacaa aatgatatct ttgggaagat
     7261 tctaccgtgt gtgatgttgg gaagtttagt cgcagttcta ctgtctggta tgctcaaaaa
     7321 aattggagag aaatacccac aattaaatgg tcagggtaat ttgatcgatg gggatgatga
     7381 acatttagag aacttgaagg gttcagctaa accagtcaat attgaaaaaa cattgttagc
     7441 aggcgtggta gcaataacga tttattttgt tgctgtctat gttgagcact tattaaaatc
     7501 actccttggc ttttctattc cttcacctgt gatcttatta gtctctctta tgggggctaa
     7561 aatgcttggt tttatcccta aaaatatcga agaaggtgga aattcgttgt atggattcac
     7621 tgttcgtggg atcacacctc ccttactttt tggcgtaggg gttgcaaaaa cagattggtt
     7681 agagctgatc gaagtattta aaaatcctgc aacgatagta acaatcattg tgacggtagt
     7741 agctattgtc gctacagctt ttatcgccgc aaaattttta aaaatgtacc cagttgatac
     7801 tgccatcgca gtttcatgtt gtagcggaca aggcggtaca ggtgctttag ctatcttagc
     7861 tgcgggtgat cgcatggaat taatgccatt tgcacaagtt gctgttcgac tagggggtgc
     7921 tatgaccgta acgttcgcta tctttttaat gggtctgcta tcataagaac ataaagaaag
     7981 gacgtgacca tgtgtttgat caaacagata tccaacgatt atttttaaaa aataactata
     8041 tcaaagacca atgggaaaat cttttgcttg attcaggaat acaaaagaag caaatcgaag
     8101 attttcaaca tttagatcaa acattgggta tataccataa agaaaagtta gtaggaacag
     8161 tatcttatca aaacaacgtg attaaatata tcgccgtgtc tgaaaaatat aaagatggtg
     8221 gacatacatt taatgtacta gtctctgcaa taattcaggc aatgagtcaa caagagattt
     8281 ttcattatat tgttttcacg aaaccgcgct atcaaaaaag ttttaacttt ttaggttttg
     8341 aaacaatcgt atctacccca aaaatagctg tattagaaat gggagatagt tctataaaac
     8401 agtacctaga gaggattcct aaagtgaatg gtgaaaaaaa agcagcaatt gtcatgaatg
     8461 cgaacccatt tacagaaggg cattattatt tagtaaaaca agctgccaat aacaacgatt
     8521 gggtatatgt atttgtactc gaaaaagaac aaaatctttt ttcgacgaag gaccgactca
     8581 aattagttca acaaggatta caaaaactga aaaatgtcat tgttctatca ggtggcgagt
     8641 atattattag ccctgcaacg tttcccacct attttttacg agaagatgat gaaatagcaa
     8701 aggagcaaat ggtcgtagat gctactttat tcaaagaaag aattgccact tatttagata
     8761 tctctgctag atatgtggga gaagaaccac tttccccaat gactcgttca tataacgaca
     8821 tactggaaac gattttaccc cctgaaataa aagttcatgt ccttgcaagg aagaaaacgg
     8881 aacaacacca agttatttct gcttctcaag ttcgtaaagc gtatcttgct gggcaattgg
     8941 aaaaaataaa atatatggtt ccagaaacaa cctatcaata cttaaaaaat aaaagggagc
     9001 gttaagtaat ggaaataaat aaatcagcga ttgctggaac attagagtca agtgatgtcc
     9061 aaatcatgat ttcaccgaat acagaaggaa tagaaatcga tttagacagt caagtgattg
     9121 agcaatttgg aaaacaaatc aaaaaagtta tctatgacac actagcagtt tatcagatta
     9181 aaaacgtaaa actcaaggta gtagataaag gggcattaga ttgcgttatt gttgcacgat
     9241 taaaaacagc gatccatcgt tccttaggta tccaacacca agaaacaccg tgggaggttt
     9301 aattagatga tgaaagaacg tttgagaaga acaatgatgt ttgttccagg aaataatcca
     9361 gcgatgatca aagatgcagg tatttatggt gctgactcga ttatgttcga cctggaagat
     9421 gcagtgtcta tggcagaaaa agacagcgca agaatgcttg tggctgaggc attgaaaaca
     9481 gtggattatg gtgacacaga attaattgtt cgaataaatg acctgcactc agaatttgga
     9541 cgtgcagaca tttttgcaat ggttaaagcc ggcgcgcatg tattacgttt acctaaaaca
     9601 gaaacctctg aagatataac agaagtagaa aaagtgatta tagaagcaga aaactatcat
     9661 aatgttccga tagggcgaac attgatgatg gcagccattg aaggtgcttc tggtgtattg
     9721 aacgcacctg cgatcgccaa agcatctgat cgattgattg gaatcgccat tggggcagaa
     9781 gactatgtga caaatatgaa aaccaaacga tatccagatg gaaacgaatt gttttttgct
     9841 cgcagtatga tcgttcatgc tgcacgtgca gcaggcattt ccgcatttga cactgtttac
     9901 tctgatgtgg atgatatgga aggattttta aacgaagtac gtttaatcca tcaattaggt
     9961 tttgatggaa aatcttgtat caatccacgg caaattccag tagtcaatac tgtttatcag
    10021 ccgtcaatca aagaaatcaa acgatcacta gacatcatct cggcaatcga agaagcaaaa
    10081 gaaaaaggtt ctggcgtaat ttctttaaat ggaaaaatga tcgataaacc aattgtagaa
    10141 cgtgcacaac ggacattgat gttagcaaaa gcatcacgat tgattgatga ggagggaaat
    10201 atccatgcat aataaacaaa gacgtagcat tccatcaagt gttttaacaa agtataaaaa
    10261 agaattccaa agtgtttcat tatcgccaca aacgattcaa cgttgtgcac caaaagtaac
    10321 gactgtaact aatcagacaa ataaattgat gcactcgatc aaagaagcta tagaaaaatc
    10381 gggcttaaaa gatggaatga cgatttcatt tcatcatcat ttgagagaag gtgattttgt
    10441 ttttaaccaa gtgatggccg tgatccgtga aatgggcatc aaagaattga ccttagcacc
    10501 aagttcttta acgaacacta tgaatgaggt ggttattgaa tgcatcaagg acggtacagt
    10561 aactcatatc acaagcagtg ggatgcgcgg cagcttaggt gaatttattt ctcatggagg
    10621 aatggacaat cctgtgattt tacgttctca tggtaatcgt ccacgtgcaa ttgaaagtgg
    10681 tgaattgaaa atcgatgttg catttctagg agtaccaaca tctgatgatt atggaaatgc
    10741 taatgcgact gttggaaaat ccgtttttgg ttcattaggg tatgcaaaag tagatgcaca
    10801 atatgcagat aaagtcattc ttctaactga tcatttagtt ccttacccta atacgcccat
    10861 tagtattccg caaacacaag tcgactatgt cgtggaagta gaagcaattg gtgatccgaa
    10921 taaaatcggt gctggtgcta cacggtttac taaaaaccca aaagaattaa aaattgctga
    10981 aatggtcaaa gatgtcattg ttcactcacc ttatttcaaa gatggctttt cttttcaaac
    11041 aggaacgggt ggtgcagctt tagcagtaac gcgttactta gctagtgaaa tggaagaaaa
    11101 acagatcaaa gcttcttttg cattaggtgg catcactaaa ccaacggttg atttattgga
    11161 aaaaggtctt gttgaaaaag tgttagatgt ccaagacttt gacaaaggag cagctgaagg
    11221 aatggcgcgg cttgagaacc aacaggagat cgatgcttcc ttttatgctg atccaagtaa
    11281 taaaggagcg gttgttaacc aattagatgt cgctatttta tctgcattag aaattgacac
    11341 aaacttcaat gtaaatgtta tgactggttc agatggtgtg ctaagaggtg cgattggtgg
    11401 acatcaagat gcagcaacgg ctaaacttac tatcatctca gcgccgttag tacgtggccg
    11461 aatacctaca gtagtaaatg atgttactac attgatcaca ccagggaaaa gtatcgatgt
    11521 attagtcaca gaagtagggg ttgctatcaa tccccaacgt aaagatctaa tagctatttt
    11581 tgaaagaatt ccacaaattc ctgtttttac aatagaagaa ttacagcaaa aagcagaaaa
    11641 aatagtaggc atcccggaac ctttgcaatt cacagatcgg atagttgcct atgtagaata
    11701 ccgagatggt tcaattttag atgtcgttcg tcaggtgaaa gaatttgaag aagagagatc
    11761 atgatgtttg atactggaga aattcaagaa atcgaggata ttttgatcca taaagaacaa
    11821 cgtgctaact tgcaaagcaa cctgctttcc aagtattcaa atagttcatt gatggtcttt
    11881 acattgaata ttcctgggcc gatcaaaaat aatccaatga ttgagcaggt atttcgtcag
    11941 ggacagcagt caattcagca aatgttttta aaaaaaaagg tggaaatgac gtacacaaaa
    12001 gaaatcaatt tgccaagtgg attggactgg tacgtaatag taacagaagc acctttgaat
    12061 ctcaaaaaat ggttggtcac gttagaagag caagacgcat taggtagact ttttgattta
    12121 gatgtcttgt tcaaaaaagg agagcagata acaattgtca gtcgccaagc tcttaatcat
    12181 ggggaacgtc cttgttttat ttgtgggaaa tcagcaaagg tatgtgcacg taatcgtaca
    12241 catactgtga aagaaatgca aaagaaaatc gaacaaatag tagccgattc cttaaaagga
    12301 gcattgaaac atgcatgata atattcaaaa aatagcacaa gaagcacaat tagcgatgct
    12361 ttatgaagtt acatgtatca ataaaccagg attggttgat ccagtagacc ccgggtctca
    12421 tcaagatatg gacattttta cttttctaca aagtagtgta gttttgactc cctattttga
    12481 agaatttatc caaacaggat tggaccgaca acatcaacca attgaagaaa cctttatggc
    12541 gattcgacag attggtttag aggctgaaac tgcgatgttc tcagtgacaa atggtataaa
    12601 tacacataaa ggtgctatct tttcattggg gatttttctt gctatttgtg gccggttaac
    12661 tatttggaaa gttccttgta aaaaaagttt ctttcaaaaa gaaattcaaa aaatgacgaa
    12721 aaatctactt aacgattttg ggaagattga tcaaacaaaa ccaaaagcat ggacttgggg
    12781 agaatatcta tttgttaacc atggattgac agggatacga ggggaagcca aaagaggtta
    12841 tccttgtgtt tttgaccgag gattgcctta ttatcaagca tatcaagggt cgcaacaaga
    12901 taagatgata gacactttac tttttctatc aatggaagta gaagatacca atttgatcaa
    12961 acgaagtaat aatagacatg tttttgaaga gtatcaatta cttattcgtc cttattttga
    13021 attagggggt gtaaaaacca tacaaggtaa aaaatatttg gattacctaa atcagcaatt
    13081 taaaaagaaa aattggagta ttggtggaag tgcagactta ttgatcctta caatcttttt
    13141 agataaaatc atggacaaag gatggttatg ttgatactat aatacattat tttgtattag
    13201 taagctaata actaaaaaat ggttcaatac aaatatttta taaaaaatgg tagtgcctat
    13261 cctttcagat tgtagacaaa gaaaaatttc tttgtctaca atttttttgt taatgacttc
    13321 agtcagtttc gtgcgcaaag cgtgcgaaac aagaaaacca tgcgtttcta cacgtggaag
    13381 aactagcata tcgaaaggag ttttttcatg tcaaatgacg ataaaagttt agcccatact
    13441 cgttggaatt ttaagtatca tattgtattt acaccaaaat atcgacgaaa agtaatctat
    13501 aggcaattac gaaaagatat tggaaaaata cttaggaagt tgtgcaaaat aaaaaacgtg
    13561 gaaattatag aagcacatgc aacgccagat catattcaca tgcttgttca agtaccatca
    13621 aaaataagta tatccagttt tatagttatc tgaaagatcg tagtgctgtg ctaatccacg
    13681 agcagcacgt aaatcacaaa tatagatacg gaaataaatc attttggtcg gaggaatatt
    13741 atgtgagtac agtcgaattg aatcaaaaga caattgaaaa atacatccgt gaacaagaag
    13801 ctgatgatcg catttgagat agtataagta aaagagagta gatgttgcaa taacaaaagg
    13861 gtaaaaatgg actacctcca gtaaaatacc gaaaaatagt ttaacttttg gagataagtc
    13921 catttaaggg tctatagaat gacaattttt ttaggggatt ttactattat tacttcaaga
    13981 cccgcttgga ttcgcaaagt gagtgaactc ttaaaactac ctgatagtag gttgttttaa
    14041 gagttatctg aaagtaaaaa ttgcatttat atttttgata aatacgtaaa tttatatata
    14101 cgtatttatc aaagttttag gccaaaggaa tattgtgtaa atacactagg attgaatgaa
    14161 tagaccagaa gaaattgcgt ccaagaacaa aagaagcatg atagtgctct atataaattg
    14221 ggcattcaag aatctgaaat ttaaaggtag aattttagtt agacttttag attttaaaca
    14281 caaaaataac catacaagca acaagaagca aagtgctata ttataaattg tccgtccgtt
    14341 tacttacata agatcattgg ggctattttt aaaagagaat aatagataat aaatgaaaaa
    14401 aaagtcaagt ccacaatcct gtgtaaaata ctatacaatg ctctcactat tttttacttg
    14461 gcaaatttaa tatattttct tgatgaagaa agccactcat cgtgttgatc aataaggact
    14521 gctccaatta aacgattggc tgaaacgcag tttgg
//
LOCUS       DAFEEZ010000073        14547 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000073
VERSION     DAFEEZ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14547
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.076"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            2..814
                     /locus_tag="LP245_002371"
     CDS             2..814
                     /locus_tag="LP245_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBL1520258.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            811..1611
                     /locus_tag="LP245_002372"
     CDS             811..1611
                     /locus_tag="LP245_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBL1520259.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1772..3040
                     /gene="rseP"
                     /locus_tag="LP245_002373"
     CDS             1772..3040
                     /gene="rseP"
                     /locus_tag="LP245_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBL1520260.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3108..4817
                     /locus_tag="LP245_002374"
     CDS             3108..4817
                     /locus_tag="LP245_002374"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBL1520261.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5029..9387
                     /locus_tag="LP245_002375"
     CDS             5029..9387
                     /locus_tag="LP245_002375"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBL1520262.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9532..10005
                     /gene="rimP"
                     /locus_tag="LP245_002376"
     CDS             9532..10005
                     /gene="rimP"
                     /locus_tag="LP245_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBL1520263.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10028..11203
                     /gene="nusA"
                     /locus_tag="LP245_002377"
     CDS             10028..11203
                     /gene="nusA"
                     /locus_tag="LP245_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBL1520264.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11225..11518
                     /locus_tag="LP245_002378"
     CDS             11225..11518
                     /locus_tag="LP245_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBL1520265.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11515..11826
                     /locus_tag="LP245_002379"
     CDS             11515..11826
                     /locus_tag="LP245_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBL1520266.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11839..14145
                     /gene="infB"
                     /locus_tag="LP245_002380"
     CDS             11839..14145
                     /gene="infB"
                     /locus_tag="LP245_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBL1520267.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14172..14519
                     /gene="rbfA"
                     /locus_tag="LP245_002381"
     CDS             14172..14519
                     /gene="rbfA"
                     /locus_tag="LP245_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBL1520268.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
BASE COUNT         4958 a         2583 c         3237 g         3769 t
ORIGIN      
        1 aatgttacgt ttttttccgc aaaaaaacaa atatattcaa gaaaaaagcg aatttcaatt
       61 taataccgat ggaccaattc ctcagcacat tgccatcatc atggacggca atggtcgttg
      121 ggcgcaaaac cgtcgtttgc cacgagttgc tggccataaa gaaggcatgg aaacagtaaa
      181 gaaagtcaca aaaaaagcat caaggcttgg agtgaaagtg ttgacgcttt atgccttttc
      241 gactgaaaac tggaagcgac caaaagatga agtaagtttt ctcatgcaac tacctgtcga
      301 cttctttgat acgttcgtac cagaattgat taaagaaaat gtcaaagttc atgtcatggg
      361 ttatgaaaac gtattgccag aacatacgca agatgctgta agacgtgcaa ttgagcaaac
      421 aaaaaacaat actggaatgg tattgaattt tgctttgaat tatggaagta gagcagagat
      481 cgtgactgct gtccaagaaa ttgccgaaga agtagcaaaa ggagaaatac acgcagaaga
      541 aatcgatgat gaattgattg ctaagcattt aatgacaggt ttcttgccta aagagttaca
      601 agatcctgag ctgatgatcc gtacaagtgg agaagagcga attagtaatt ttctgttatg
      661 gcagatcgca tatagtgagc tgtattttac aaaagcgctt tggcctgatt ttgatggtgc
      721 gcatcttgaa gaagcaatcg cctcttatca aaatcgagac cgtcgattcg gcggtgtaaa
      781 aaaaacagaa gatgagaaag gggatcagtc atgaaacaac gtgtgatcac agcagctgtg
      841 gcgctagtct tgtttattcc gattatatgg atcggaggca tagcggttga gcttacagca
      901 gcaatcttag cggtagtagg agtttacgag ctgttccgga tgaaaggatt gacactctta
      961 agttttgaag gagttttatc cgccgttggt gcagtgttac ttgttttgcc aaaagaaaga
     1021 tggtttttct ttcttccaga gaatgtaagt acatttatgt tattttatct tatagttatg
     1081 attcttttag gaacatcagt tatttctaaa aatacgtata cgattgatga agcaggtttt
     1141 cctgtgcttg tcagcttgta tgtgggaata ggtttccaga attttgtcaa tgcacgaaca
     1201 gaaagcttgg ctgttttgat atttggtcta tttattgttt gggcaactga tatcggagca
     1261 tatatggttg gtcgacgtta tggtcagcat aagttaagtc ctgatatttc gcccaacaaa
     1321 acgattgaag gtgcgctcgg tggtatcggt agtgctgttg tagtcgcatt tctttattta
     1381 ttgctatacc cagcaaaaga actattcaat catggtatgt ttgtcatgct tctgatgacg
     1441 attatttttt cagcagtcgg acaatttggt gatttggtcg aatctgcaat caaacgtcat
     1501 tatgatgtga aagactcggg aaatatctta ccaggccatg gtggaatctt agaccgtttc
     1561 gacagtttgc tgtttgtatt tcctatcatg catttatttg gcattattta gtaagtatac
     1621 ctgcgtttct ttgtgaattt cataaaagac gcaggttttt atttttcatt atattgatac
     1681 tattggtgtc tttggtatac tatggtaaaa ttatagtgtt ttatcgttgt tttataaaaa
     1741 acacaaaaaa caagtaaagg agaaaaaagc tatgaaaacg attctgacat ttatcatcgt
     1801 ttttggtata ttagtgattg ttcatgagtt tggtcatttc ttctttgcga aacgatcagg
     1861 aatcctcgtc cgcgaatttg ctatcggtat gggtccgaaa atttatgggc atcaagcaaa
     1921 agacgggaca acatatacgc ttcgcctatt acctattggc ggttatgttc gaatggcagg
     1981 caatggggat gatgaaacag aaatggcacc aggaatgcct ctttctcttt tactaaattc
     2041 tgacggcatc gtagagaaga taaatttaag taagaaaatc caattgacaa atgctatccc
     2101 gatggaattg agccgttatg atttagaaga tgagctgact atcactggtt atgtgaatgg
     2161 agacgaaaca gaagtagtaa cctaccctgt tgatcacgat gcgacgatta ttgaaaacga
     2221 cggaacagaa atcagaattg cgccaaaaga cgtacagttc caatcggcta aattgtggca
     2281 gcgtatgctg accaactttg ctggacccat gaataacttt attttggcaa tcgtgttatt
     2341 catcattctg gcatttatgc aaggtggtgt tcaagtgacg aacactaatc gcgtaggaga
     2401 gatcatgcct aatggagctg cggcagaagc aggcttaaaa gaaaatgatg aggtagtcag
     2461 tgtggacgga aaagaaatcc attcatggaa tgatctgaca acagtcatta cgaaaaatcc
     2521 aggtaaaaca ttagacttta agatcgaacg agaaggtcag gtgcaatctg tcgacgtgac
     2581 accgaaatct gtagagtcaa atggcgaaaa agttggccaa cttggtataa aagccccaat
     2641 gaatacaggt tttatggata agatcattgg agggacgcgt caagctttca gcggttcatt
     2701 ggaaattttc aaagccttag gatcactatt tacaggtttc agtttagata aattaggcgg
     2761 acctgtcatg atgtaccaat tgtcttcaga agcagcaaat caaggtgtaa caactgttat
     2821 tagtttgatg gcgcttcttt caatgaatct cggaatcgtc aatctgcttc cgattcctgc
     2881 cttagatggc gggaaattag tcttgaatat ttttgaaggg attcgcggga aaccattaag
     2941 tcaagaaaaa gaaggaatat tgacattagc tggctttgga tttttaatgt tgttgatggt
     3001 gctagttaca tggaacgata ttcaacgatt ctttttctag aaaaagttga caaatagggt
     3061 ataataacaa acgataacta ttttgaggaa ataaaggagt atatagaatg agacaatcaa
     3121 aaatgttgat tccaacatta cgcgaagttc caaatgatgc agaagtatta agccatcaaa
     3181 tcttgctaag agctggatat atccgccaag tatcagcggg tatttattca tatctgccat
     3241 tagcaaatcg tgtattggaa aaactgaaac gcattatgcg ggaagaattt gaaaaaatcg
     3301 gagcggtaga aatgctgatg cctgccatct tgccagcaga actttgggaa gaatccgggc
     3361 gttacgaaac atatggacca aacttgtatc gtttcaaaga ccgcaatgat cgaaaaatga
     3421 tccttggacc aactcacgaa gaaactttta ctgatttgat gcgtaatgaa atcaattcat
     3481 ataagaaatt acctttaaat ctttatcaaa tccaacctaa atatcgtgac gaaaaacgac
     3541 ctcgcttcgg tttgcttcgc ggaagagagt ttatcatgaa agatgcatat tctttccatg
     3601 caacggaaga aagtttggac gagacatata aagattacga aaaagcctat accgaagtat
     3661 tcaagcgttg tggcttagaa tttcgctcga tcatcggaga cggcggcgca atgggcggga
     3721 aagactcaaa ggaattcatg gcgatctcag aaatcgggga ggatacgatc tgttattcga
     3781 ctgaaagtga ttatgctgca aacttggaga tggctacaag ctactatgta tcaaaaaaat
     3841 cgcatgaaac acagcttgaa ttggagaaag tagctacacc taacgtaaaa tcaattgacg
     3901 aagtagcaga tttcttttct gttgaacctc aaaaaatcat caagtctgta ttgttcattg
     3961 cggatgaaca acctgtcctt gttttggtac gtggagacca tgaagtcaat gacgtaaaac
     4021 tgaaaaactt tttatctgct gactttttag aagaagcaac agaagaagaa gcacaaaaat
     4081 atctaggtgc tgagtttggt tctgtcggac cagtcggtgt ttcagatgac gtaaaagtat
     4141 atgcagaccg ttatgtccaa gatttagcga atgccattac tggagcgaac gaaacaggat
     4201 tccactataa aaatgtgaat ccagaacgcg atttcactgt gctttcttat gaagatcttc
     4261 gttttgtaca agaaggagat ccttcaccag acaacaacgg tgttcttgcc tttactcgag
     4321 gaatcgaaat cggacatata ttcaaaatcg gcactcgtta cagtgaatct atgggagcaa
     4381 ctgtactaga cgaaaatgga cgagaaaaat ttgtgattat gggctgttat ggtatcggtg
     4441 taagtcgttt attatcagca atcgtagaac aacattcaga tgaacaagga atcaattggc
     4501 caaaaggaat tgcgccattt gatctgcata tcgtccaaat gaatctaaaa gacgaatacc
     4561 aaacaagcct gacgaatgaa ctagaagaag cgatgacaaa agctggctat gaagtactgg
     4621 ttgatgacag aaatgaacgc gcaggagtga aattcgcgga ttctgatttg attggctgtc
     4681 caatcagaat cactgtcggt aaaaaagcag tggatggaat cgtagaagtg aaaatcaaga
     4741 aaactggcga aatggttgaa gtacgtaaag aagaattggc gaatacttta ccaatcctct
     4801 tgaaccaagg cgaataataa gcgttaaaac acagaaaata aaaatagctg aatcagctgt
     4861 ttttgacaat ctgatgattc gcttttaaaa ttggaactgc gatttgaatc gcagttccaa
     4921 ttttttaatg taaaactcag aaaaaacgag tatactaaaa ggtactgaaa aagaagagga
     4981 taagatgcga tcaattgcat tgtttctcat cagaaagggc gtatatcttt gtcagaaaaa
     5041 cgagatttat ttgaaaaact gttggaacaa atccaactag aggaagcaga aaaaaatcat
     5101 ccactgctta ctgctggtga aatggatagt gtagtggtcc atcgtaaatc gcgtttatgg
     5161 gaatttacgc tacatttttc caaaattttg cctattatgc tatatcggtc attgactcag
     5221 catctgacta tcgcttttaa agatattgca caagtcaaac tgaatatctt agcagatgac
     5281 cagacattcg atgaacagct cttgcaagat tactgggccc aagctttgga aaatcagcaa
     5341 tgcgatacac cactagcaca gcaagtattg aaaacgcagg tacctgtgat aaaagatcgt
     5401 aaagtcatct tgccaatcga cagtacagga gctatttctt atttgaagca acaatacttg
     5461 ccattagtag aagagttgtt cgtcagttac ggattcccaa aatttcgtat cgaaccagaa
     5521 gtggatgagc agcaagcgga acgagtattg aaactttttg aagaacgcaa acaagaacag
     5581 gcagaagcct ttatgaagca agcagctgaa agtctagttg tccacgaaca aaagaaaaag
     5641 gaaagaaaag agcaatcgcc agctcttgaa ggacccatcc acatccagct aggacgaaat
     5701 attccagccg atgaaccaac gacaccaatg atcagtatcg ttgaagaaga acgaagagtc
     5761 acacttgagg ggtacgtatt cgacaaagaa gtcagagaac tacgttcaaa acgcaagatc
     5821 ttgactttga aaatcacaga ttatacttca tcatttatcg tcaaaaaatt ctcgaacggc
     5881 gaaaaagatg aacaagtatt tgatgcgatc agtgtcggta gctggttaaa ggtacgagga
     5941 agtattcaag aagatacgtt tgtccgtgat ttggtcatga atgcgcaaga tatcatagaa
     6001 gtcaaacata cacctcgcaa agattatgct cctgaagggg aaaaacgagt agagcttcat
     6061 gttcatagca atatgagtac gatggatgca acaaacagca tctctgatct tgtggcacaa
     6121 gcagggaaat ggggacaccg agctatcgcc attacagacc acggtggtgc gcaagccttt
     6181 ccggaagcac atagtgctgg aaaaaaagca ggtgtgaaaa tcttatacgg cgtggaagcg
     6241 aatgtcgtag atgatggtgt cccaattgct tataatgatg cacatgaagc attgagtgaa
     6301 gccacatatg tcgtatttga cgtggaaacg acaggattgt ctgcagtata tgacacgatc
     6361 atcgagctag ccgcagtcaa aatgtataaa ggaaatgtga tcgaaagctt tgatgaattt
     6421 atcgatccag gacatccttt gtcacgaaca acggtagatc tgactggtat cacggatgga
     6481 atggttcgag gatcaaagtc ggaagaagaa gtattgcgga tgttccttga attttcaaaa
     6541 gatacaattt tggtagccca caacgcggct tttgatatgg ggttcttgaa tactagctac
     6601 gcaaggtatg gtattcctga agcggccaat ccagtcattg atacgttgga attagctaga
     6661 tatctgtatc ctcaattcaa acgtttcgga ttaggtgtgt tatctaaaaa atttggtgtc
     6721 agcttggaac agcatcaccg agcaatctat gatgctgaag caactggtca cttagcatgg
     6781 atctttgtga aagaggcaat ggacaatcat aacatgcttt atcatgatca gctaaatgag
     6841 catatcggag aaggagattc ttacaaaagg gctcgacctt tccatgtaac gattttagca
     6901 aaaaatcagg caggactgaa agatttgttc aaactgattt caatgtcgaa tgtcgaatac
     6961 ttcgaacgcg tcccacgaat accacgctcc caattgaaaa agatgcgtga aaatctattg
     7021 atcggctcag cttgtgataa gggagaaata ttcgaagcca tgatgcaaaa aggggtagaa
     7081 gaggcaagaa accgagcaaa attctacgat tatattgaag ttatgccaaa agcggtctat
     7141 gcgcctttga tcgagcaaga attggtaaaa aatgaacatg atttggaaga aattatccaa
     7201 aatttggtag aaatcggaaa aagtttggat aaaatcgttg ttgcaacagg taatgtacat
     7261 tatctgaacg aagaagatgc catttaccga aaaattttga tcaattctat gggcggagcg
     7321 aatccgttga atcgtcatag tttgccggat gtccatttcc gaacaaccga tgagatgcta
     7381 actgcatttc actttttagg ggaagaaaca gcgaaagaga tcgtagtaga aaatacgaat
     7441 aaaatcgcag atatctgcga agaagtgatt ccagtcaaag atgaacttta tacaccgaag
     7501 attccaggtt cagaagatga aatatcagaa ttgagttaca caaaagcaaa acaaatgtac
     7561 ggagatccgt tacctgagat cattcaaaaa cgattaaaaa aagagttgaa ttctattaat
     7621 ggtaatggct tctcggttat ttatctgatc gcccaaaaac tagtgcataa aagtaatgaa
     7681 gatggctatc tagtaggttc acgtggctct gttggctcta gctttgttgc gacgatgaca
     7741 ggaatcactg aagttaatcc gttagcccct cattattatt gtccagagtg ccaatattcc
     7801 gagttttttg aagatggtac gtatggttct ggatttgaca tgccagaaaa acaatgtcca
     7861 aaatgtggtg cacgcttaaa caaagacggt catgatattc catttgagac atttttagga
     7921 ttccatggag acaaagtgcc cgatattgat ttgaacttct caggtgatta tcaagcagaa
     7981 gcccataact atacgaaagt attgtttggc gaagactatg tttaccgtgc cggaacgatt
     8041 ggtacagtcg ccgacaaaac agcatatggc tatgtaaaag gatacgaaag ggacaataat
     8101 ctgcagtttc gaagtgcaga agtcgacaga ttagcaaaag gcgctactgg agtcaaacgg
     8161 acaaccggcc agcatccagg ggggatcatc gttattcccg attatatgga tgtctatgat
     8221 tttacgccga tccaatatcc agcagacgat caaaattcgg aatggaaaac gactcatttt
     8281 gattttcact cgattcacga taatgtattg aaattagata ttctagggca tgatgaccca
     8341 actgttattc ggatgcttca agatttatca gggatcgatc cacaaacgat ccctacggat
     8401 gacccggaag tgatgcggat atttgccggt cctgaagtac ttggagtaag tcaggaacaa
     8461 atttattcca aaacagggac attaggtatt ccagaattcg gcactcgttt tgttcgaggg
     8521 atgctagaag aaacgcatcc tacaactttt gcagaactac tgcaaatttc cggactatct
     8581 catggtacag acgtatggtt aggaaatgcg gaagaattga ttcgacgagg agatgcgaca
     8641 ctggcggaag taatcggctg tcgtgatgat attatggttt atttgatcca tgctggatta
     8701 gatagcggga tggcatttaa aatcatggaa actgttcgta aaggacaatg gaacaagatc
     8761 cctgatgaat tgcgagaaac ctatctatcg gcgatgaaag aaaataatgt gcccgactgg
     8821 tatatcgatt cttgttcaaa aatcaaatat atgtttccga aagcccatgc tgcagcttac
     8881 gtattgatgg ctcttcgtgt cgcttatttc aaggtttatt tccctatttt gtattactgt
     8941 gcatactttt ctgtacgtgc agacgacttt gatctagtct ccatgtgcaa aggaaaagat
     9001 gctgtgaaac aagcaatgaa agaaatcacg gacaaaggat tagatgcttc cgtaaaagaa
     9061 aagaatcaac tgacagtgct ggagttagcc aatgaaatgc tggaacgagg attcaaattt
     9121 ggaatgattg atttgtataa atcggatgcc gttaactttg ttattgaagg tgatacgttg
     9181 atcgcaccat ttagagctgt cccaagtttg ggaaccaacg tggcaaaaca aatcgttgaa
     9241 gcaagaaaag acggtccatt tttatccaaa gaagatcttg ccacccgcgg taaagtttca
     9301 aaaacattga tcgaatatat gaacgacaat ggcgtattga aagatctacc agatgaaaat
     9361 caattatcgt tattcgatat gctataagca tctgttttcc tgtctgcttg taattttaag
     9421 cagagtatgg tatagttctt ataggtaatg atactaactg tgagtgagcg gatttttcgc
     9481 tcactctttt taatggaatt acgcacttaa ttttttaagg aggcgaaact tttgagtagc
     9541 gtcgttgaaa cagtcacaga aatggtgaca ccgattttag atgaacaaaa ttttgaactt
     9601 gtcgaagtcg aatttgtaaa agaaggaaaa agctggttct tacgagtatt tattgacaaa
     9661 gaaggcggta tcgatatcga agaatgcgcc tttgtcagtg agaaactgag tgaaaaactt
     9721 gatgcagcag atccagatcc gattcctcaa gcttatttcc tggaggtatc ctccccggga
     9781 gcagagcggc cattgaaaaa agaaagcgac tatgaaaagg cacttggtga ttatgtccat
     9841 gtctccttat accaaccagt agatggcgaa aaacaatatg aaggatttct tcaatcattt
     9901 gatgctgaac agcttacatt gaaaatacgc ataaaaacac gagaaaaaga attgactttt
     9961 gaccgaaaaa atattgcaaa agctcgctta gctatccaat tttaatcacg gagaggaatc
    10021 agaaaaaatg agtaaagaaa tgttaaatgc gttagacgct ttagaagctg aaaaagggat
    10081 ctcaaaagaa atcgtgatcg atgctttaga agcagcattg gtttctgcat acaaacgtca
    10141 ctatggccaa gcacaaaacg tcgaagtgga atttgatcag aaaaaaggaa agatccatgt
    10201 ctatgcggta aaagaagtaa cggaagaagt gatggattca cagttggaag tctcattgaa
    10261 agatgcactt ttaatcaatc cagcatatga gatcggtgat acgatccgtt ttgaagtaac
    10321 accaaaagat tttgggcgga tcgctgcgca aacggctaaa caagttattt tacagcgtgt
    10381 acgtgaagca gaaagaacga ttatttataa cgaattcagt gcttatgaaa aagacatcat
    10441 gcaaggaatc gtcgaacgcc aggataaacg ttatatttat gtcaatcttg gtaaaattga
    10501 ggcagttctt tctaaacaag atcaaatgcc aaatgaattt tatcaaccac atgatcgaat
    10561 caaagtttat gtttcccgag tagaaaatac gtctaaaggt ccgcaagtat ttgttagccg
    10621 cagccatcca gacctattgc gccgcttatt tgagcaagaa gtaccagaag tctatgatgg
    10681 aatcgttgaa attgtcagca tcgcccgtga agctggcgat cgttcaaaag tggcagttcg
    10741 ctcaaatgat ccaaatatcg atgcagtcgg tacatgtgtc gggccaaagg gacaacgagt
    10801 tcaagcaatc gtcaatgaat taaaaggcga aaacatggat atcgtcgaat ggaatgaaga
    10861 tccagctgta ttcattgcaa atgcattgaa tcctgcacaa gtcatggatg tgatcttcga
    10921 tgagacaaat ccaaaggcct gcacagttgt cgttccagac taccaattat cgctagcaat
    10981 cggtaaacgc ggacaaaacg cacgtttagc tgctaaattg actaaccata aaatcgatat
    11041 caaatcagaa tctgacatga cggaatttta tgaaaatcaa gaacaacaaa aagaaacaga
    11101 agaactgcat gatgaagcaa tcgttcagtc agatttaaca gacgatgaat atgaaacaat
    11161 tgcattcaac aatgaaacgg tcgaagaaaa accagaagct taactttagt aaggaggcaa
    11221 agagatgaaa caaaggaaaa ttcctttacg caaatccgtg gtttcaggtg aaatgaaacc
    11281 taaaaaagag atggtccgaa tcacccgttc aaaagaaggg gaagtatcga tcgatccaac
    11341 tggaaaaatg cctggacgag gagcgtatgt ctcacttgag ccggaagaag tacaacaagc
    11401 ttgggataaa aaaattctcg atcgagtact cgaaacaaca ttaacagatg agttttatca
    11461 agaacttctt gactatgtca ctcaccaaaa agcacgtaaa gagttatttg gaaaatgaat
    11521 acagttaatc ggcaaaaagc catgaatctc atcggtctag cgatgcgcgc gggaaaacta
    11581 atcacgggtg aagaactgac cattgctgaa atccgcaaac aaaaagcaaa attggtgttt
    11641 gtggcaaccg atgcaagcga gaatacaaga aaaaagataa aagataagag ttcatattat
    11701 gaagttcctt gctttgagct attttctgaa gcagaaatca cgcagatgat cggaaaacct
    11761 cgcaaggtat tcggaataat ggatgccgga tttgcgaaga agaccaagga gctaattgaa
    11821 ggttaggaag gtgattgcat gggcaacaaa agaatctatg aattagcaaa agaactcaaa
    11881 aaatctagta aagacgtcgt ggaaaaagca caacaacttg gcatcgatgt gaaaaaccat
    11941 atgggtgcga ttactagcaa tgatgagaag aaattgcaac aagcgttcaa aaacccaagc
    12001 acgaaacaac aagctgcaca acaagcaagc agaaaaccag ccaatcaaca gccgaacgat
    12061 caacgtaaaa aagaaacaac gaacaatcaa caaaaaaata aaaataaccg cagttatcaa
    12121 gatcgcggtc aagggagcgg tcaagtgaat caaggaaaaa aaccaacaac aaaccaaaat
    12181 aatacgggaa ataccagcag ccaaaatcgt caaggaacga gccaaggcgg caatcaaaac
    12241 cgtactaaca ataacaacaa accaaacaat aacaatcgcg gcaaatttaa taataataac
    12301 cgtaatcgtt ataataaaaa aggtaaaaaa ggcaaacagc aacaatcaac taaaccagct
    12361 gtaccaccac gcaaattccg tgaattgcca gatgtattag agtatactga aggtatgaac
    12421 gtagcagata ttgcgaaaaa aattcatcgt gagccagcag aaatcattaa aaaattattt
    12481 atgcttggtg tcatggtcaa tcaaaaccaa gcactggata aagatacgat tgaactgtta
    12541 gcgacggact atggcatgga accacaagaa aaagtccaag ttgacattgc tgatatcgat
    12601 aaattcttcg aggcagaaga agtcgatcca gataaattag tctcacgtcc gccagtcgta
    12661 acgattatgg gacacgtaga ccatgggaaa acaactttat tggatacatt acgccattca
    12721 cgtgtaacaa gcggcgaagc cggcggaatc acacagcata tcggtgccta ccagatcgat
    12781 attgatggta aaccaatcac tttcttggat acaccaggac atgcggcctt tacaagtatg
    12841 cgtgcacgtg gagcaagtat cacagatatc acgatcttag ttgttgctgc agatgatggc
    12901 gtcatgccac aaacagttga agcaatcaac catgccaaag ctgcaggcgt tccaatcatc
    12961 gtcgctgtaa ataaaattga taaaccaggt gcaaaccctc aacatgttat gcaagaatta
    13021 agtgagtatg agttaattcc tgaagcatgg ggtggagaaa cgatctttgt tgagatctca
    13081 gcgaaattcg gccaaaacat cgaagaattg ctggaaatga tcctgttagt cgcagaagta
    13141 gaagatttaa aagcagatcc aacacaacgc gcaatcggaa cagtgatcga agcacgtctt
    13201 gataaaggta aaggtcctgt gtcaacctta cttgtccaag aaggaacact tcatgttggt
    13261 gacccaatcg ttgtcggtaa tacttacgga cgtgtccgtg taatgacaaa cgatcttggc
    13321 cgtcgcgata aagaagcagg acctgcaacg ccagtagaaa tcactggctt gaatgatgta
    13381 cctcaagcag gtgaccgttt cgtagtcttc gaagacgaaa agacagcacg tgcagcgggt
    13441 gaagaacgcg cgaaacgtgc attattagaa aaccgtgctg ccacaagccg tgtgactttg
    13501 gataacttat ttgaaagcct gaaagaaggc gaattgaaag aagttaacgt aatcatcaaa
    13561 gcagatgtac aaggttcagc agaagcactg gctgcatcat tgaagaagat tgatgtggaa
    13621 ggtgtccgtg taaaaatcgt ccattcagct gtcggagcaa tcaatgaaag tgatgtaacc
    13681 ttagcagcag ccagcaacgc tattatcatc ggtttcaacg ttcgtcctac accgcaggca
    13741 aaagtgcaag ctgatactga agaagtcgat attcgtcttc accgtatcat ctataaagcc
    13801 atcgaagaaa tcgaaactgc gatgaaaggg atgctagacc ctgaatttga agaaaaaatc
    13861 accggtcaaa tgatcgttcg tgaaaccttc aaagtttcta aagttggtac gattgcaggt
    13921 gcctatgtaa cagaaggata tattcgtaga gatagcggtg tccgtgtaat ccgtgacgga
    13981 atcgtaatct atgaaggcca acttgcaagt ctgaaacgat tcaaagatga cgtgaaagaa
    14041 gtcaaaatgg gttatgaatg tggtgcaatg attgaaaaat tcaatgacat caaagtagat
    14101 gacgtaattg aaggatttat catggaagaa gtcaaaaatg actaaaaact gataaaagga
    14161 ggccaatcat tatggctaac taccgtgacc gccgagtcgg tcaagaaatc ttaaaagaag
    14221 tcaatgatat tttgcgcaaa aaggtccgtg accctcgtgt ggagaacgta acgatcacag
    14281 atgtgaaagt tacgggggac ttacagcaag caacgatcta ttacagcatt ttatctgact
    14341 tagcatcaga taagaaaaca gcacaagatg gattgaataa agcatcagga ttgattcgtc
    14401 gagagttagg gcacaatcta agtatttata agacacctga attgttcttt gaacttgatg
    14461 aatcagttgt ctatggcaac catatcgatg aattgcttcg cgacttgaac aaagactaat
    14521 caaaaactcc cgcaaatcct gtgaaat
//
LOCUS       DAFEEZ010000074        14114 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000074
VERSION     DAFEEZ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.077"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..552)
                     /locus_tag="LP245_002382"
     CDS             complement(<1..552)
                     /locus_tag="LP245_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HBL1520269.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVG"
     gene            complement(568..1047)
                     /locus_tag="LP245_002383"
     CDS             complement(568..1047)
                     /locus_tag="LP245_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBL1520270.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1053..2077)
                     /locus_tag="LP245_002384"
                     /pseudo
     CDS             complement(1053..2077)
                     /locus_tag="LP245_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2094..3200)
                     /locus_tag="LP245_002385"
     CDS             complement(2094..3200)
                     /locus_tag="LP245_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBL1520271.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3429..6026)
                     /gene="adhE"
                     /locus_tag="LP245_002386"
                     /gene_synonym="adhC"
     CDS             complement(3429..6026)
                     /gene="adhE"
                     /locus_tag="LP245_002386"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBL1520272.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6331..6711)
                     /gene="yajC"
                     /locus_tag="LP245_002387"
     CDS             complement(6331..6711)
                     /gene="yajC"
                     /locus_tag="LP245_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBL1520273.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(6808..7953)
                     /gene="tgt"
                     /locus_tag="LP245_002388"
     CDS             complement(6808..7953)
                     /gene="tgt"
                     /locus_tag="LP245_002388"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBL1520274.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8171..8869
                     /locus_tag="LP245_002389"
     CDS             8171..8869
                     /locus_tag="LP245_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBL1520275.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9037..11676)
                     /locus_tag="LP245_002390"
     CDS             complement(9037..11676)
                     /locus_tag="LP245_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL1520276.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(12295..13326)
                     /gene="queA"
                     /locus_tag="LP245_002391"
     CDS             complement(12295..13326)
                     /gene="queA"
                     /locus_tag="LP245_002391"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBL1520277.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            13519..>14114
                     /locus_tag="LP245_002392"
     CDS             13519..>14114
                     /locus_tag="LP245_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1520278.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
BASE COUNT         3957 a         3095 c         2542 g         4520 t
ORIGIN      
        1 gcctacgaga taacctccca taaacaaagc agagatcgaa gcaccaccag caacaagtga
       61 atacatgata aaagcagtac ttggaggaat gaccatacct gtcggagctg acgcgatatt
      121 gaccgctgtc gcaaacttcc ggtcatatcc ttcttccact tgctgaggga tcaacactcc
      181 accaatcgcg gtagaagcgg caatggccga gctagagatg gaaccaaata aagcattccc
      241 taacacattc gtatgagcca aagcccccgg cacgcgcccg acgaacaaca tcgcaaaatc
      301 cactagtttc ttagctatcc ctccattatt catgataatg cccgagagaa cgaaaaacgg
      361 aatagcgatc agcgaaaaac tattgatact tcccaccatt ttttgagctg aactaaaagc
      421 agaaacatca aacggtataa ctaacaataa agtcatcatc gatgagaatg caatacttat
      481 agcaatcggc atccctaata caagcaacac aacaaataca aaaaataaca ctaatccggc
      541 ttctattgcc attttattcc tccattttta tattttttct tgaattgctg gcttgttgct
      601 taatgtatcg attagattga tcaggctata gataatgatg agtacccccg atacaggtac
      661 tgacagataa acatatccca taggaatact taaagaaggc gagatctgcc ccattgtcaa
      721 tgtgacagca ttccatccgc catacaccat gatcatcgca gcaaatacca gaaataaact
      781 ttgaacaaca acttctaaaa ttttactttt tttgccagtt aatttttcac ttaaaaccgt
      841 tacggctaaa cgtgcttttt gtcccacaac atacgcggaa gacaacatgg caaaccagac
      901 aagaccgaat cgaacaagct cttccgtgac cgtatttgga tttcctaaaa ccgttctgga
      961 aaatacttgc cataaaacaa cagcgaccat cccaacaagc aaaacagctc ccaggatctc
     1021 taataccttg tttaaaatca ttttcattac agctacgctc cttgctcttg gatcttttga
     1081 taaaggtctt tgtaggtagg atcgtttttg aatatatcat gaagtggggc aactgcctct
     1141 cgaaacggtg tattatctac atcattgaat tggactccat gttcttcttg tgctaaagct
     1201 ttttcttctt caattgcttt tgcaaaagct tcaatttcaa aaaccgttga ttctttcgct
     1261 gcttcttcaa tggctttttc ctgttcatca gttagctgtt ctttgatggc atcattcatg
     1321 atgatgatat ctggcacacg tgtatgctca tcataggaat agtatttagc taccccgcca
     1381 tgtccagctg tatacaagac aaattcattg ttttctgatc cgttgatcaa attggattga
     1441 agagacgtgt acacttcatc acttcccata ggtacgggcg aaccgcctaa aagctctacc
     1501 attttgatag cggtttcgct ttgcatcaca cggatcttct ttcccttcaa atcttccggc
     1561 gtatggatcg gaccgtctac catataaaag ctgcgctgac cagaatcata ataggtcaat
     1621 ccggtaaatc ctaaattttt ggtcgattgg tagattggct ccattatttc ttcattatcc
     1681 atcaccttaa agaaatgttc ttcatcattg aatagataag gaacggaaaa aatcgaataa
     1741 tctttagaga aactttccaa cgctgaggca cttacttttg tgaaatctac tgctcctgac
     1801 tgtgtcaatt cgatcagttc acgttctcca cccagttgtc catctgggaa atactggatc
     1861 tgtacggaac catctgtttt ttcttttact aaacgcccaa attcattcat tgcatcaatt
     1921 actggctgtt gcttgcataa gcaaagcgca aggtaactat ctcatttacg tctgcatctg
     1981 cgacagttgc cacactagaa ttatttccgc agccgcttag acctagcaga cctaggctaa
     2041 gcgaacttgc tgcaaacagc agtgatgttt ttttcatatg ggtttccttt cttttaacaa
     2101 taagagacga gcaattctgt caaacaaagc accgttaacg actgtccata aggcattgct
     2161 gtgattccga tattccgata aaaatctaaa ctgtccccca ttcctgtccc gattgaaacg
     2221 ttttgaactt ctcctttttc atcgatttgt tcaagcaatc cttggatagc acgataagcg
     2281 acttctttat attcttgtgg taaataacgt ttatggaccg ctttcaaaat accgtaagca
     2341 aatcctgcag ttgcagaaga ttctacgtaa gaagaaggat catccaacaa cgtatgccat
     2401 aaaccgcttt cagactgata agtttttaat gcacgcactt gtgcttcaag tgtttcgatc
     2461 aataatttgc gcaatgcatc ttctttcgat aattctaaga tttcaatgat ctctggaata
     2521 gcaatcgtca accagcagtt tccacgagcc caaaatgctt cggcatagtt atgatttcct
     2581 tcaaacgtcc agccgtgata ccacaatcct gttcgtttat ccatcaagta tttgatatgg
     2641 atcataaact ggtaacgagc ttcttctaaa tattctgggc gattcaacag tttcccgatt
     2701 tttgccaaag gaagcactgt catcatcaat gtatcgtccc acaactgatt cttattttcc
     2761 ggtccatatg tggcatgctg taacccgtct tcatttgtcc gaggcatgtc attcatgacc
     2821 cattctgccc attgttctaa ataaggcaaa tagcgtgaat ctttcgtgtc ttcatacaag
     2881 taagccatag tcaatagcgg tgccattgta ttgacgtttt tgggcggagc gccttcttcc
     2941 atacgatcct caaaccattc attgaccact tgataagcgc gaggattttt tgtcatctgg
     3001 taatttttat aaataccata tagaccgaca ccttgtggcc aattccacac tgtccagctt
     3061 ttgtcatcta ctttcagtcc atcaaagtcc aacaaaaatt caccattatc gtctttgatc
     3121 gttgtcaggt tttcaacgag caggtcaatt ttttctttca ctaattcttt aggtacaaaa
     3181 atctcttctt taataatcat ctttacgcca cctttttaaa cgctttcatt ttatatcctt
     3241 aatatagcag taataccgtc cactataaat atcgcttttt gaacaaaaac tgtctaaaat
     3301 tgacctaaat gttaaataac aaaagtaact ttcagttact tggaaattaa aaaaagaact
     3361 tggagaaaca acgttttcca agttcttttt catctatttt cttatctttt ttctacgctt
     3421 tcttttgctt atccgttgta agcatcaatg atgatctgtt tcaattcaga gatcaatggt
     3481 tctttcggat tagctgtcgt acattggtct tcgtaagcta attcagccat acggtctacg
     3541 gttgtatcta gtgtttcttg tgtgactcct tgagctttta gactcatgtt gatgccgaca
     3601 gattttccta attcataaac agccgttgct aaagcttcga ctaattcctc tgttgtttcg
     3661 cctttcagac ctaagaattt tgcgatatct gcgtaatctg tatctgcacg gaaatagtca
     3721 tatttaggga acatcgcatg tttttgtgga tcttttgcat tatagcggat aatatgcggt
     3781 aaaagaatcg catttgtccg tccatgaggg atcccgtatt ccccgccgat tttatgtgcg
     3841 actgagtgac aaatacctag gaatgcgtta gcaaacgcca taccagccat tgtagaagcg
     3901 ttgtgcattt tttcacgtga ttccatatca ggtgttttta ctgatttttc taaatagtca
     3961 aagactaact tgattgcttg taggctcaat ccacgtgtat aatctgaagc catgactgaa
     4021 acataggatt cgattgcatg tgttaacaca tccatcccgg tatctgctgt gacagatgct
     4081 ggaactgaca tgacgaattg aggatcgacg attgcgacat ctggcgtcaa tgcataatct
     4141 gctaacggat atttcacatg tgtttcactg tcagtgatga ccgcaaatgg cgttacttca
     4201 gaaccagtcc ctgatgttgt cgggatacat acgaattgtg ttttttctgg tttgtcgatc
     4261 ttatatgtcc gtttacggat atccaagaat ttttgttttg caccaaagaa agatgtgtct
     4321 gggtgttcat agaacatcca cattccctta gctgcgtcca ttgcagaacc gcctccaaga
     4381 gcgattactg tatctggctt gaagtctgcc atcagtttcg ttcctgcgta tacggtattt
     4441 gtcgatgggt tcggttcaac atctgagaag acttcgatct tcacatcatt tttacgtcgt
     4501 gccaatactt cacgaactgt atcgcagtaa ccgaattgga ccataccagg gtcacaaacg
     4561 atcatgacac gttcaacgtt ttccattttc tctaagtaca atagagagtt cttttcaaag
     4621 aagatttttg gcggtaattt gaaccattgc atgttatttc tccgtttcgc tacagttttg
     4681 acattgatta agtttacagc agagacgtta cgagaaacag agttcttacc ataagaaccg
     4741 catcccaaag tcaatgacgg aatcatttcg ttatagatat caccgatgcc gccttctgca
     4801 gatggtgtat tcactaaaat acgacaagct ttcattcgaa gaccgaattt gacatgcaac
     4861 tcttcgtttt ctgaatggat aactgctgta tgtcctaatc ctccaagatt caacatacct
     4921 tcacacaaat caaacgcatg gtccgtgttg ttagctttga tcatggcaag aactggagaa
     4981 agtttttctc ttgatagcgg ataatctggg cctacgcctt ccaattcagc aatcagcatt
     5041 ttcgttcctt ttggtacact gattcctgcc aattttgcga tttccatcgc agaatgtcca
     5101 acgattgatg gattgaccgc atattttcct tcgttcatca ctgcatcttc taatttttgc
     5161 aattcatctg gttttacgat ataaacttgg tgtgcttgga attctgcttt tactgctgca
     5221 tagatttctt tatccacgat cacagcttgt tcagaagcac aaatcattcc attatcaaat
     5281 gttttcgaaa cgatcaaatc gttcactgca cgtttaattt ttgctgtttt ttcaatataa
     5341 gctggtacgt tacctggacc tacacctaaa gctggttttc ctgtagagta agcagacttg
     5401 accattccag ctccacctgt cgctaagacg atcgcgatac ctggatggtt cattagcata
     5461 gaagtcgctt cgatcgaagg atgttcgatc cattggatac aattttcagg agctccggca
     5521 gcgatagcag catcacgtac cactcgtgct gcttctgcag aagatttttg ggcacttgga
     5581 tggaaagcaa aaacgattgg atttcttgtt ttcaacgcga tcattgattt gaaaatcgtt
     5641 gtggaagtcg gattcgttgt tggagttact ccgcaaacca caccgactgg ttcagcaatt
     5701 tcaatcaacc ctttttggac atcttcattg atcacaccaa ctgttttatc atgtttgata
     5761 ttatgccaaa tatattcgga cgcatacata tttttgattg ctttatcttc gtaaacaccg
     5821 cggcctgttt cctctacagc catcttcgct aatggcatat gttgatccaa agctgccatt
     5881 gccatttcat gcacgatatg gtctactttt tcttgatcaa agctttccat ttctttcaat
     5941 gctgcatttg ctttttctgc caaatcatca atcattgctt gtacgtcaat tgtcttcgtt
     6001 ttttcttttt ctattacttt agccatcatt atcctcctaa tgggtcatgg ttatttgtta
     6061 aataattcac atgtatatca tacaatattt atttttctat gtaaacactt ttttgtgatt
     6121 tttttcacag ttatttttaa atataaaatt gctttattta caggtgtttg tatagaaaaa
     6181 tatataaagt tatttattat tatttatatg acacacccga ttattcaata ttgagcaata
     6241 tatcccatgc tcttatctct ttcttttttg aataaaaaat gaggtaggac atctttctgc
     6301 cctacctcgt ctttaaataa gctttgatac ttatttttct tccttctctt ctgtctcttc
     6361 cagcgtttct gttgtttcag tttttacttc aactgtctca gctggttctt ctgttgtttc
     6421 aacagtagtc gttgcatcat ttgttacgac agtccctggt ttgaccgttt tgattgctgc
     6481 acgatcgtac tcaaggaaga tcccttcgca gtctaaaaca actgtccgtt tgtcattgtc
     6541 gatttctgaa acaactccat gtaatccgcc gatcgttacg actgaatcac ctggtttcat
     6601 gctatctaac aagttttgac gttcttgctg ttgtttcttt tgcgaacgtg acataaaaaa
     6661 ccacattgct aatagcgcga taaacatcac aagcattggt aatgttccca tttttttcac
     6721 ctcactaatt ctgtatctac aaaaaacact ttagcagaaa aatgctgata acactagttt
     6781 tttacttaat ttttaaaaga ttttccttta gaagcttttt gcgttttctt tattgaaccc
     6841 gtattcttca aaaaaggctt ctctaaattc aagcaaatta tcatccatga ttgcttgacg
     6901 tacttgtttc attagattca acaagaagta taaattgtgg taagaagtca aacgaatccc
     6961 aaatgtttca tcacatttga tcaaatggcg gatataggca cgtgtatagt ttttacatgt
     7021 ataacaatca catttctcat caattggacg gaaatcatgg gcatatttcg catttttcac
     7081 tactagacgg ccttgagaag tcatacatgt gccatttcga gcgattcgag taggcaagac
     7141 acagtcaaac atgtctactc cacggataac accatcgatc aatgaatcag cagcaccgac
     7201 acccatcaag taacgtggtt tgttttcggg gatcaacggt gtagtgaatt ctaatacacg
     7261 attcatttct gatttaggtt ccccgacaga taacccgccg attgagtaac cagggaaatc
     7321 catcccgact agatctttcg cgctttgacg acgaagatct tcaaaccctg ctccttggat
     7381 gattccaaat aatccttgac ggtctggatt agcatgagct ttcaatcctc gttctgccca
     7441 tcgagacgta cgttctactg attttttcac gtagtcgtaa ctttcatcga atggtggaca
     7501 ttcgtcaaaa ctcatcatga tatcagagcc caatttattt tggatgttga ttgctttttc
     7561 tggtgataaa aacatacgcg aaccgttcaa gtgatttttg aaatgcacgc cttcttcttc
     7621 gatattccgc atatcactta atgaaaaaac ttgaaagccg cctgaatctg ttaaaatcgg
     7681 ttgatcccag ttcataaatt tatgcagtcc gccagcttct tctactaagt cttcaccagg
     7741 gcgtagccat aaatgatatg tattacttaa aataacgcca gcacccattt ctttcaactc
     7801 ttctggggac attgttttta ctgtagctaa tgttcctact ggcatgaaca ttggtgtggg
     7861 gaaagttccg tgtggcgtga tcaattcccc taaacgcgcg ccagtatgtt tttctttctt
     7921 gattaaacga tagcgaatgg caggttgcgt cattcatttc cctactttct atataaaata
     7981 tcttgacaac tcccaccatc ataatcgttt caagtgcttt ttgcaagttc cctcggcttc
     8041 cttctacttt atttaatatt ctttttttta tccttttttt atgaataaca aaaaaaagaa
     8101 aaacattatg acagaaatat tttttgatac atggtatatt ggtgttatta aagaaaagga
     8161 gggaaaaatc atgcaatctt ctgcagaatt aaaacgccaa gcaaaagaga gtctaaaagg
     8221 acgttgggga caagctgttt tactaaatct aatccctaca ttgattggta ttgctactat
     8281 tcttcttatt atgattccta ttatcttgtt tgccaccacc atatatgatg gatcagcgag
     8341 cgtctcagaa gcgacaactt caggaggcgg tagttcagga ggcggtggcg gaattatttc
     8401 cagcatcatt agcgctttgt tcatgagcgg tatttcttgg acttatcttg atattttacg
     8461 tggacaaaaa gatcagatcg aaccattcaa agatgcattt cgtggattca aaggtttgtt
     8521 tatcggcgga gtgatcagct tagctgtgct gatctcgatc tttacaacat tatggggttt
     8581 gctattagtt attcctggaa tcattaaaag ctattcttat tctcaaagct attttattta
     8641 ctacgatatc gtccaagaaa caggacaaac acctaaagta ctggatacga tcactgcaag
     8701 tcgaaaattg atggatggtt ataaaggaca acttttctgg ttagatcttt catttatcgg
     8761 ctggcatatc ttagcattag caactgctgg tattggttat ctatggctca gcccatacat
     8821 ttctgcaaca aaagcagcat tttatgaaca attgccaaaa gatatttaaa agagagtgtg
     8881 acttgtgacc gagggggtgg caggagaaca ccgtttatcg agaggcagta aaagaaacat
     8941 tcagcccatt agcaaaaagg aggtgtgaca acattcatgt cacacctcct ttttgtatag
     9001 ttccagtaaa aagaaaatca acttagaaac agttaatcat tcctcttctt ctgcttccgg
     9061 taatcgatgg aacttgatca gttcattcac cgcgattggt acgatagata aaatccctac
     9121 caagaaccag tgattcaaac tgatgtgtac taggccgaat agttcttgcg taaatggcag
     9181 caaagcaaca gccgttgtaa tagctaatgc cagtaacgcc atttctacca aagctttatt
     9241 ggtcgctaaa ttgactttga agatcgattg gctgctgcgt acattgaaca catgcagaat
     9301 cgatgaataa gctaagatca agaatgcaac agtttgaccg acatgctgac ttgcgtctac
     9361 ccatgggctg atagtatcga cataactacc taaataataa ccaaacaagg ttacgatggt
     9421 gaagacccct gcatttatgg caattttttg caataaacct cgagcaaaga tcccttcatt
     9481 tttcggaatg ggtggctgat ccatgatgcc gtgttccgct ggctctcttc ctaaagcaaa
     9541 tcctggaagt ccatcagcaa ctacattgac aaacagtagt tgcacagctg taaatggtgc
     9601 tccccatcct aacagcatcg caatcaaaac aataaagatc tccgaaatat tacagcttag
     9661 caaaaagttg atagctttac gaatattctg ataaaccgaa cgtccttgac tgacagcgtc
     9721 tacgatcgtc gcaaagttgt catccgtcaa aatcatatct gcggcacttt gcgccacatc
     9781 tgttcctgtg atccccatgg cacacccaac gttacttgct ttcaacgctg gtgcatcatt
     9841 cacaccatcc ccagtcatcg ctacgactgc acccgtacgt tgccaagatt tgacgatccg
     9901 gatcttgtct tctggcgtta cccgagcata gacagagaga gctttgacac gcgcatctaa
     9961 ttcttcgtct gataattgat gcagttctga tcctgaaagt gcttctgacg gatcattcaa
    10021 gatacctaat tctttcgcta tggcactggc agtcaccaca tgatctccag tgatcatgac
    10081 tgttttgatg ccagcctttt tcgctcgctt gattgctcct ttactttctg gacgtggtgg
    10141 atcgatcatt ccgatcagac caatcaaacg taagtctttt tccagtgctt cagaagaaat
    10201 atcttgcggt tcttcgtcat aagtagcata accaacagca atcactctca gtgcccgttt
    10261 accaaagcga tcattaacga tcgccgcttg ttctacatcg cctgaactaa agcgcggagc
    10321 aagaacatcg aatgctcctt tggtgattga gatgtatttt tcgcccattt ggtgaactgt
    10381 tgtcatcatt tttcgttcag aatcaaaagg aagctcgttt actcgtggat atttttcttc
    10441 taattctgcc tttgtatgat aattctcttc aacagccctt acgatggcta cttctgttgg
    10501 attacctttg ataacaaggt cgtcatcttc ttgctcgacc gtcacatctg tacatagtgc
    10561 agccattttc aatatttcca tcgcgctgtt cgtcattgaa tcttcgatat tcgttacttc
    10621 atcttctttg ctccataccc ggcggacgcg catttcattt tgtgtcagcg ttcctgtttt
    10681 gtctgagcag ataacattag cggttcctag cgtttcaact gctggcaact gtcggatgat
    10741 cgcatgtttc ctcgccatct tctgcacacc gtatgcaagt gtcaacgtaa caataacagt
    10801 caaggtttcc ggtacagctg caacagccaa ggaaatcgaa gtcatgaaca tctcaaggag
    10861 tggttctcct tgcagttcac caatcacaaa tactaaagcc gcagccgcta aagcgatcat
    10921 actgattcgt ttgcctagct gattcaatcg gacctgtaaa ggtgtttttt gcatagtatt
    10981 ttcgttcaaa agatccgcga tcttacccat ttctgtagcc atgccaatgg cagtgacgat
    11041 cgctttccca cgacctgcag caaccgtaca tcctttaaat accatattaa gttggtcacc
    11101 taatgactca tcttcttcag caataaatgc tgcatctttt tcaactgctt cactttctcc
    11161 agtcaacgcc gattcttcta cacgtaattg tgatgcttcg atcaaacggg catcggcaga
    11221 aatagcatca ccggactcta aaacaagaat atcacccact accagttgct ctgactcaac
    11281 agtggtcact ttgccgtctc gtatgacagt tgccgtttgt ttattcatat cttgcaagga
    11341 ttccagtgct ttttctgcgt ttccttcttg gacaatcgcc aataccgagt tgatcacaac
    11401 gatagcgatg atcagcagtc cttcaaataa atccccatgt tctgtagcaa atgcggtata
    11461 aaaggaaatc accgctgcta caagaaggat gatcgttgta aaatcggaca agcttcgaaa
    11521 gaattttttg atcatcgatt ctttcggcgc ctcatcgaat ttattcaatc cctgcttttt
    11581 tcgccgttca tccacttctt gtgaagacaa cccagtatct ggatctgctt ctgttacctt
    11641 ctttacttct tctattgtct gcttgtattc ttccatccta ttcctccttt aaaatcttcg
    11701 tacaaaaaaa ggtacttatt ttactataac atcctttttt tatttacttc aaataaaggg
    11761 cttatcgatt atttgttaag aaagcgtaaa atttaaagtg cttatatttg caaacgctac
    11821 caaaggatgc tattatatag atgtaaggaa ggaggatacc atcaaataga cagaagaatt
    11881 tctcgataga acagtgtaag caaacaaagt tgttagaagt acaggtttca cccagacatg
    11941 cgtgtagagt acaaacctat aaatagtgaa tgcgtatgga tgtttggatc acgaagtatc
    12001 cgaaacaaga agtaatgcga tacgtaacaa ttgaataacg taaacgtctg aaaattgaat
    12061 aggaacaaga gatgtttcaa atgttgaaga tgtaacgaaa acaaaatttt tgtttaacat
    12121 gaagaaattc aacaccgtgc tttgcatgta tgatggaaag ttacaatcat ttctgtttat
    12181 ttgaatcctt ccgaggtaca agaaagccga gcttatcgag agctcggctt tttctttgtc
    12241 ataaaatctt tgtaaagctt ttttgttatt caaaactagc ggcttttcat aaccttattt
    12301 cacgaacatc gcatctccaa aactaaagaa acgatagcgc tcttcaatcg catgctggta
    12361 agcagataaa gtcaattctc ttcctgcaaa ggcactaact aacatgacta aagtcgattt
    12421 tggcaaatgg aaattagttg agaaagcttc taccactttg aattcatagc caggcgtaat
    12481 gaaaatatca gtccatccgc tgtctgcttt gatttctcca ttaaatttcg ttccaatcgt
    12541 ttctaatgtt cgaattgaag ttgttccgac agccacgatt ttcccgccat ttttacgtac
    12601 ttggttcaat cgctcagccg cttcttccgt caaacggtag aattcactat gcatatggtg
    12661 ttcttcaatt ttatctacgc tgacaggtcg gaatgtacct aaccctacat gtagtgtcag
    12721 atagactaat tcaacaccct ttgcttcgat ctcatcaagt aattctttcg taaaatgcaa
    12781 tccagctgtt ggcgctgcag cagaaccatt ttctttcgca tagacagttt gatagcgatc
    12841 tgggtcttcc agacgttctt tgatatatgg aggcaatggc atttctccca atgattcaag
    12901 aatctctaga aaaattcctt catactcaaa gtcaatgatc cgtccgccgt gttccaattc
    12961 ttctttcact actgcttgca atctgccatc accaaaagag attcttgtcc caactttggc
    13021 acgtttcgca ggtttgatca atgtctccca cgtatctcct tgtgtattcg ttagaagaag
    13081 gacttctaaa tgcgcaccag tatctggttt ttctccatat aaacgagcag gcagaactcg
    13141 tgtattattc ataactagcg catcaccagg ctgtaactct tcaatgattt catggaaatg
    13201 tttatcttcc atctctccag ttttccgatc caaaacaagt aaacgagaat gatcgcggtc
    13261 ttttaatggt gtttgtgcga ttaattcttc cggcaagtca aaatcaaaat cttctgttgt
    13321 taacatatcg tcactcactt tctatcatgt gcttcatcat tctatcatgt ttttcgttct
    13381 gttggcaaaa tcagcacttt ttcacttcta ttttttgttt tcctaaataa aaaaactacc
    13441 ctatttgtat tttttcattg ttttaggcat actagtaata gatagttctt cattgaaaat
    13501 agaaaaagag gtggcaccat gattgaattt caaaatgtgt caaaaattta taaaggtgga
    13561 aaagtcgctg tagaggacgt caatctttca tttgaaaagg gtgagttcat ttgttttatc
    13621 ggtacgagcg gaagcggaaa aacgacgacg atgcggatga tcaaccgaat gactgatcca
    13681 acacaaggga aaattttgat tgatggaaaa tccatccaag aaattgatcc agtggaattg
    13741 cgacgtcaga tcggctatgt tatccaaagt attggattga tgcctcacat gacgatccgt
    13801 gaaaatatca ctcttgtcca aaaattgttg aaagtcagtc aagaagaacg gaataaaaca
    13861 gctgaaaaaa tgattgatct tgtggaattg ccccgtgaga tgttagatcg ctacccacat
    13921 gaattatctg gtggtcagca gcagcgtatt ggagtcgttc gtgcccttgc agcgaatcaa
    13981 gatatcatct tgatggacga gccattcggt gcgcttgatc caatcactcg tgattccttg
    14041 caagaccttg tcaaagattt acaagagcgt ttgggaaaaa cgatcgtatt tgtaacccat
    14101 gacatggatg aagc
//
LOCUS       DAFEEZ010000075        14059 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000075
VERSION     DAFEEZ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14059
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.078"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..318
                     /locus_tag="LP245_002393"
     CDS             <1..318
                     /locus_tag="LP245_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1520279.1"
                     /translation="KAIIPENLDEVKLYLWEDNGEIVGFSGVSAEELVMLFLDPDFIG
                     KRYGSQILIELIETEDIKRIDVNSQNKYAKHFYLSHGFEIESEEDLDGFGKPYPITHL
                     VKK"
     gene            732..1550
                     /locus_tag="LP245_002394"
     CDS             732..1550
                     /locus_tag="LP245_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL1520280.1"
                     /translation="MNKNPHNLKLVAVDMDGTFARTDYTYDIPRFKAVLSRMKAVDCQ
                     FVVASGNQYYQLRSLFPNYYDELSFVAENGAFVKDKTEVLFSADMPRKAIEVVLDLCK
                     DYPEVKNVMCGLNSAYCERGKVSQAFFDLTNIYYHRLEWVADFAEVQDKILKFAPTMP
                     VEKTEFYVELFREKLAGLLVPTSSGHGSVDLILSECHKTFGLKMLVERLGINPDQCVA
                     FGDGGNDIEMLEYCGLSYEMDNATEAVKQVAKHQCPSNDEDGVLVTLDRLFPNT"
     gene            complement(1623..1982)
                     /locus_tag="LP245_002395"
     CDS             complement(1623..1982)
                     /locus_tag="LP245_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL1520281.1"
                     /translation="MSDNLFLEVQPEVFKQVPRLKDGFLLTLNDGSNQFSSAEGCCMI
                     GDHFLLVSTQHYIPAYDLTIPCEEATVKTSEYDTTFINGHLVLEVTPSNQTIRLKNES
                     GILDSNVQVYFDSSDAS"
     gene            2083..2262
                     /locus_tag="LP245_002396"
                     /pseudo
     CDS             2083..2262
                     /locus_tag="LP245_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303240.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2603..3205
                     /locus_tag="LP245_002397"
     CDS             2603..3205
                     /locus_tag="LP245_002397"
                     /inference="COORDINATES: protein motif:HMM:NF013878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520282.1"
                     /translation="MLDPLFTDETFITFGFGHLVELAEPGHYDEKWQNWKLESLPIFP
                     DRYDFEVAKDKGKQFKIVAELLKKANTIIVATDSDREGENIAWSIIHNANAFSKDKTF
                     KRLWINSLEKDVIRSGFQNLQPGMNYYPFYQEAQTRQIADWLIGMNASPLYTLNLQQK
                     GVQGTFSLGRVQTPTLYLIFQRQEAIENFKKEPFFEVEAK"
     gene            3299..3631
                     /locus_tag="LP245_002398"
     CDS             3299..3631
                     /locus_tag="LP245_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase I"
                     /protein_id="HBL1520283.1"
                     /translation="MGNQEGIIADVQTKEKKTNSPSSFSLSSLQSKVNQLYKATASQT
                     LKAMQGLYEAKLLSYPRTDTPFITENEFAYLKANFGKYSGFLGLDLEMLLSLIMIRSN
                     NSTQILTN"
     gene            complement(3782..4761)
                     /locus_tag="LP245_002399"
                     /pseudo
     CDS             complement(3782..4761)
                     /locus_tag="LP245_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332307.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(4766..5533)
                     /locus_tag="LP245_002400"
     CDS             complement(4766..5533)
                     /locus_tag="LP245_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL1520284.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            6022..6447
                     /gene="lacA"
                     /locus_tag="LP245_002401"
     CDS             6022..6447
                     /gene="lacA"
                     /locus_tag="LP245_002401"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HBL1520285.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            6464..6979
                     /gene="lacB"
                     /locus_tag="LP245_002402"
     CDS             6464..6979
                     /gene="lacB"
                     /locus_tag="LP245_002402"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HBL1520286.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            6990..7922
                     /gene="lacC"
                     /locus_tag="LP245_002403"
     CDS             6990..7922
                     /gene="lacC"
                     /locus_tag="LP245_002403"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HBL1520287.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            7925..8905
                     /gene="lacD"
                     /locus_tag="LP245_002404"
     CDS             7925..8905
                     /gene="lacD"
                     /locus_tag="LP245_002404"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBL1520288.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            8933..9250
                     /locus_tag="LP245_002405"
     CDS             8933..9250
                     /locus_tag="LP245_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL1520289.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            9250..10956
                     /locus_tag="LP245_002406"
     CDS             9250..10956
                     /locus_tag="LP245_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1520290.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            11098..12504
                     /gene="lacG"
                     /locus_tag="LP245_002407"
     CDS             11098..12504
                     /gene="lacG"
                     /locus_tag="LP245_002407"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBL1520291.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            12527..12799
                     /locus_tag="LP245_002408"
     CDS             12527..12799
                     /locus_tag="LP245_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HBL1520292.1"
                     /translation="MLSDTLEKVQHLFRPGFEKVYIVSFEDCPMIPELEATPLLKCGK
                     WYVSTGKEWICHSDLELSAFEWEFLQSLDVEIRETIHFEVNYLPFQ"
     gene            12820..13719
                     /locus_tag="LP245_002409"
     CDS             12820..13719
                     /locus_tag="LP245_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBL1520293.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         4526 a         2318 c         2784 g         4431 t
ORIGIN      
        1 aaagcaatca ttcctgagaa cttagatgag gttaaacttt atttatggga agataacgga
       61 gaaattgtcg gttttagtgg tgtaagtgca gaagaattag ttatgctatt tcttgatcca
      121 gattttattg gtaagcgata tggtagtcaa atattaattg agctgattga aactgaagat
      181 ataaaaagaa ttgatgttaa tagtcaaaat aaatatgcaa aacattttta tttaagccat
      241 ggatttgaaa ttgaatctga agaagactta gatggttttg gtaaaccata ccctataacg
      301 catttagtaa aaaaataatt catgaatggt ttattacctg attgaacatg aataaaagta
      361 atatttttat tttgatggcc tatttctagg ttatgaatta tccagatcaa atttgtgtat
      421 tacattcagt aataaggtgc ttatcttagg atcaacttat gatactagct gaccaaggat
      481 gtaccagtta tagaaaatca gttaaagtaa aaatgataaa aatcttatgt caacactgat
      541 ttaggctgac ctgtgggtta ggagaaagac aggtcggtag cttttaatac aaaaaatggc
      601 ttgtatgtat ctagatagtt aactgaaatt agaaatgttc ttatttttaa cggagtaaga
      661 aaaataggct gctttaggtc tgaatacttt ttcaatataa tgaagatatc aaaggcgaca
      721 ggagtgtttt tatgaataag aatcctcata atctaaagtt ggtagcagta gatatggatg
      781 gaacatttgc tcgtactgat tacacatacg atatcccaag gttcaaggct gttttatcgc
      841 gaatgaaagc tgttgattgt caatttgttg ttgcaagtgg aaatcaatac taccaattga
      901 gatcgttatt tccaaattat tatgatgaat taagttttgt tgctgaaaat ggtgcttttg
      961 ttaaagataa aacagaggta ctattttcag ccgatatgcc tagaaaagcg atcgaggtgg
     1021 tccttgattt atgtaaagac tatcctgaag taaaaaatgt gatgtgtggt ctgaatagtg
     1081 cctactgtga aagaggaaag gtgagtcaag cattttttga tctaaccaat atctattacc
     1141 atagattaga atgggtagct gattttgcag aagttcaaga taaaatttta aaatttgctc
     1201 cgactatgcc tgttgaaaaa accgaatttt acgttgaatt gttccgtgaa aaattagccg
     1261 ggctattagt acctaccagt agtggtcatg gttctgtaga cttgattctt tctgagtgcc
     1321 ataaaacttt cggcttgaaa atgttagttg agcgcttggg gattaatcct gaccagtgcg
     1381 ttgcttttgg agatgggggc aatgacattg agatgttgga gtattgtggt ctgagttatg
     1441 aaatggataa tgcaacggaa gctgttaagc aagttgctaa gcatcaatgt ccttcaaatg
     1501 acgaagacgg tgttttagtg acgctcgatc gattgttccc taacacgtaa acactaggta
     1561 attcatcaaa aaacctcgat ataagaaata ttcgaggttt taaaactata tttagaacag
     1621 atttacgaag cgtctgatga gtcaaaatag acttggacat tgctatctaa aataccactt
     1681 tcattcttta aacgaattgt ttgatttgat ggagttacct ctaatactaa atgcccatta
     1741 ataaaggtag tatcgtattc agatgtttta actgttgctt cttcgcaagg tattgttaaa
     1801 tcatatgctg gaatataatg ttgtgtggaa actaataaaa aatgatcacc aatcatacag
     1861 catccctctg ctgaagaaaa ttgattagag ccatcattta aagttaacaa gaatccatcc
     1921 tttaaacgag gtacttgctt aaatacttct ggttgtactt ctaaaaataa attatcgctc
     1981 attttcacga ccaccatcga cttccacagt tgaaattgac attttattta acacacctat
     2041 tcccccttaa ctataactca attctatata aaaaatattc tatttcatga ttggctggcc
     2101 caagaaaata tcaattctga gtggttattt ccctcgacag cccattatga tcttcatatc
     2161 actgagaagc agtttcataa ggtgatggcg catgttggtg atctcttagg aatcaacttg
     2221 gaagacaaag agaaaaaatt gcgagtcaga aaaccgtttt gagatatgaa cagcatttgc
     2281 cttcacgcct tagcgatttt aaataatagc cttgaaagtg attatggaaa agccctctac
     2341 gctcaatgca aaattgacgt agaaactatt tttgatcgat tgaaaggtgt atttggtatg
     2401 tgaagaaccc atgtcagagg caagaacgtt gcacctactg acattggaat gatgcttatg
     2461 agcatgaatc taaccaaatt atcccttgag gctagaagaa aagcggaagc ttttcaacac
     2521 aaagcagcca aaaataaaaa acgcgacgaa gcaatcacat ttatgattat tcatcgcgtt
     2581 ttttatattt agagctagtt atttgctaga cccactattt acagatgaaa cgtttatcac
     2641 ctttggtttt gggcatttag tggaattagc agaaccaggt cattatgacg aaaagtggca
     2701 aaattggaaa cttgaatctt tgccgatttt tcctgatcga tacgattttg aagttgcaaa
     2761 agataaggga aagcagttta aaattgttgc agaacttctc aaaaaggcaa atacaattat
     2821 tgttgcaaca gatagcgaca gagaaggtga aaatatcgcc tggtcgatta tccataatgc
     2881 aaatgccttt tcaaaagata aaacatttaa aagactatgg atcaatagct tagaaaaaga
     2941 tgtgatccga agcggttttc aaaatttgca accaggaatg aattactatc ccttttatca
     3001 agaagcgcaa acacgccaaa ttgccgattg gttgatcggc atgaacgcaa gccctttgta
     3061 tacgttaaat ttacaacaga agggcgtaca aggtacattt tcactaggac gtgttcaaac
     3121 gcccacctta taccttattt ttcagcgcca ggaagccata gagaatttta aaaaagaacc
     3181 ttttttcgag gtggaagcta agtaaaacaa gggtcattta agggcgttct aagccccaca
     3241 cagcgtttta aaacccaaga ggagcttttt agcttttgtt tcttctaaac aagctaaaat
     3301 aggcaatcaa gaggggataa ttgctgatgt tcaaaccaaa gagaagaaaa cgaatagtcc
     3361 gagttcgttt tctttaagta gtttgcaatc aaaagtcaat cagctttata aagcgacagc
     3421 gagccaaact ttaaaagcta tgcaaggact gtatgaagca aaattattga gttatccaag
     3481 aacagataca ccatttatta cagagaacga atttgcttat ttaaaagcga attttggcaa
     3541 atatagcggt tttttaggac ttgatcttga aatgttgtta tcattgataa tgatacgttc
     3601 aaacaacagc acccaaattt tgacgaatta gtgaaactct atgaaaaaga cgtagtaaaa
     3661 catgcaacat cctattctaa tcagctggta aagcttaatt aggttatata agcttgaaaa
     3721 taaagggttt gtccaatatg gacaagcctt tttcttatgt tttgccacag atttgccaca
     3781 cttattgtgt aagagtatca aggataggta taatttgata ctttgttttt ttagtgatgt
     3841 gcaaataaat ttctgttaca cgactacctc tagaatgccc tacacggtct tgaattgctt
     3901 ctaggggtat tccttactct gctaagaaac taatatgcgt atgacggaat atatgggtcg
     3961 taatatgttt attaaaacta agtttattat caatatcaat tcctgctcgt tttggattac
     4021 cttttcgatt taattttcca ttttcaggtg agttgaggaa attgttaagg acactataat
     4081 gaagaggtgt tccattatag tcgggtttat gacgactttt ggaagtaaaa atccatccat
     4141 tatctttata atcaggattg aatctcatat gttggtgatt taactcaatt tcctctttaa
     4201 gaatttctat agccctttta gataattgga catttcggta actttgtaag ttttttacat
     4261 taccttcata gctattttct gcagctcctc cgtgagtgga ctgactaatg atgatatttt
     4321 gcttttcaaa atattgatag gcaccaatat tttggagttt cgactctgta agtcaacagg
     4381 gccattagtt agaataccta ttgggatgcg gtttttatgt agagccagca gtagttgatg
     4441 tatctcagga atcatcgtaa tctgatcgag ttcatattca tagtcagctt ggaagtctag
     4501 agcttctgtc ctagaaatac tatcgatgcc aaattcttcc atagtcttct gacagcgaaa
     4561 aattctaagc tgctcaatac tgatgagttt tttcgtgtat ttaggaaaag caacatcaga
     4621 ccaatatctg aaacgtttgt aaatgttatc tatttgttgg atatcaatcg ttggaaaaca
     4681 tttctcaacg ctacgtttaa aggggagttg atggtcataa agagtgtcat caaggtcaaa
     4741 aacaatattt ttataagtca taattctagt ccgcttttaa aatagtagtg tactggctaa
     4801 attcctctaa gtgttgaggg ctaatctggt tatctgtaat gatggtatcg agttgatcta
     4861 gattatagaa gttaaagaaa tcgtatcgat cgaatttagt actgtctact aataagaatt
     4921 tttctacagc attgtttagg gcaagttgtt gaatcacacc ttccttgtca ctatatgtag
     4981 caatagaatt atgggtaaca gcatttgcac taacaaaagc tttggcaaat ctaattgctt
     5041 ttaaatttgt cgaagccatt gaacctacaa aagctccagt tatttctcta tattcaccgc
     5101 caagaagcaa taaatcaatg gtttcgctat catttagaat caagaacaca gggagactat
     5161 ttgtaatgac acgaatttta taacctttac gacctttcaa ttctaatgcc agttgttcaa
     5221 gtgtagttcc aggtccaata aaaatagtat cgccatcttt gattaaagag caggcttttt
     5281 tagcaatgtc aattttttct tttgtattta gacttttctt ctcgatatgt gtcttttcaa
     5341 gtggcttttt agaggaaagc aattgtgcac caccatgagt acgtgttaaa agtccatcag
     5401 cttctagagc atcaaggtct ctacgggctg tcatatcgga aatatctagt tcatctatta
     5461 tttcttttat ggttatggtc ccatcaatct ttaacatatc taaaattttt tctaatcgtc
     5521 gttttttgtt catatgaaga cccttctttc ataaagtaat ttttttccaa agataattct
     5581 cttttaattg tatcataaaa gacaatattt tcaaggtaaa acaaacaatt tcaaacaaaa
     5641 acaaatgtta gatgatgaaa taagaacaga ggattgacgt atattagctt aggtcagatt
     5701 ttgtataaga cgaaaataaa gtaggacctc ttaatcagta agttatagaa agtaaaagac
     5761 ttttgtaata cttgaataga tatttcacgt ccattttgtg atggattaaa tgaacaaaaa
     5821 tgaacaataa tttaacggtg ttatctattt tttaaaaaaa caaataaaaa aacaaaaaat
     5881 aaacaaaaaa agtgttgctt tttgtttgaa tgcttgatat tatataaaca aagaaatgat
     5941 gaaaacgttt tttcgaacat tttgcaaaat gttttctact tctacgtagc atttctttct
     6001 aaaatttagg aggtggtcaa aatggctatt gttgttggtg cagatctcaa aggtacgaga
     6061 ttaaaagatg ttgtgaaaaa ttttcttgta gaagaaggtt ttgaggtaat tgatgtgact
     6121 aaggacggac aagattttgt tgatgttacc ttggcagttg cctctgaagt aaataaagat
     6181 gagcaaaact taggtattgt aattgatgct tatggagctg gtccattcat ggtagcaact
     6241 aaaattaaag gtatggttgc agcagaagtt tcagatgaac gctcagctta tatgacacgt
     6301 ggacataaca attcacgaat gattacggtt ggcgctgaaa tcgtcggtga tgagcttgct
     6361 aaaaacatcg ctaaaggttt cgtcaatggt aaatatgatg gcggacgtca tcaaatccga
     6421 gtagatatgc ttaacaaaat gtgttaagaa aaggagttaa ggaatgagaa tcgcaattgg
     6481 atgtgaccac attgtcacag atgaaaaaat ggcagtatca gaattcttga aatcaaaagg
     6541 acatgaggtc cttgatttcg ggacatatga ccacgcacgt actcactacc ctatctatgg
     6601 taaaaaagtc ggtgaagcag tagtaagtgg tcaagcagac ttgggagtat gtatctgtgg
     6661 tacaggtgtc ggcattaaca atgcagtcaa taaagttcca ggtgttcgct cagcgttggt
     6721 tcgtgatatg acatcagcta tatatgcaaa agaagagtta aatgcgaatg ttatcggttt
     6781 cggtggaaag attactggtg gtcttcttat gaatgacatc attgaagctt tcattgaagc
     6841 tgagtacaaa ccaacagaag aaaataaaaa attgattgca aaaatcgaac acgttgaaac
     6901 acataatgca catcaagcag atgaagattt ctttacagaa ttccttgaaa gatgggaccg
     6961 tggtgactac cacgattaag gtataacaaa tgattctgac agtcacacta aatccttcag
     7021 tagacatctc ttatcctcta gaaacattga aaattgatac agtgaatagg gtgaaagatg
     7081 ttagtaagac agctggtgga aaaggcttaa atgttactag agtcttgtat gaatctggtg
     7141 ataaagttac tgctacaggt ttcttaggtg gtaaaattgg tgaatttatt gaaagcgaat
     7201 tagaacaatc tcctgttagt ccagcttttt ataaaatctc aggaaacact agaaactgta
     7261 ttgctatctt acacgagggt aaccaaacag aaattttgga acaaggacca acaatttctc
     7321 atgaagaagc agaaggcttt cttgaccact atagcaatct tattaaacaa tcagaagttg
     7381 tgacaatttc aggaagttta ccttcaggac ttcccaacga ttattatgaa aaacttatcc
     7441 aacttgcttc ggatgaagga gtagcagtcg ttttggattg ttcaggtgca cctcttgaaa
     7501 cagttctaaa atcgtcggct aaacctactg ccatcaaacc taataatgag gaactttcac
     7561 agttgcttgg aaaagaagta acaaaagata ttgaagaact caaagacgtt cttaaagagt
     7621 cactttttag tggtatcgaa tggatagtgg tctcattagg tcgaaacggt gcctttgcaa
     7681 aacatggtga tgttttctat aaggtagata ttcctgatat cccagttgtt aatccagtcg
     7741 gatcagggga ctcaacggta gctggtattg catcagcttt aaatagtaaa aaaagtgacg
     7801 ctgacttatt aaaacatgcg atgacattgg gtatgttaaa tgctcaagaa acaatgacag
     7861 ggcatgtgaa tatgactaat tacgaaacac taaactcaca aattggagta aaagaggtat
     7921 aaaaatggta cttacagaac agaaacgcaa atctttggaa aaaatttcag ataaaaacgg
     7981 tgttatctca gctttggcat ttgaccaacg tggtgctttg aaacgtttga tggcacagta
     8041 tcaagataca gaaccaactg tagctcaaat ggaagaacta aaggttttgg ttgctgatga
     8101 acttacaaaa tacgcttctt caatgttgct tgaccctgaa tatggacttc cagcaacaaa
     8161 agcattggat aaagaagcag gtcttcttct tgcctatgaa aaaacaggtt atgatacatc
     8221 aagtacaaaa cgtttgcctg actgcttgga tgtttggtct gcaaaacgta tcaaagagca
     8281 aggcgctgat gccgttaagt tcttgcttta ctatgatgta gacagctcag atgaacttaa
     8341 ccaacaaaaa caagcttata ttgaacgtgt tggttctgaa tgtgtcgctg aagatattcc
     8401 tttcttcttg gaaatccttg cttatgatga agaaatctca gatgcaggtt ctgttgaata
     8461 tgcaaaagtg aaacctcgca aagtcattga agcgatgaaa gttttctctg atccacgctt
     8521 taacattgat gttcttaaag tagaagtacc agttaacgtt aaatatgtcg aaggttttgc
     8581 tgatggtgaa gtagtttaca gtaaagctga agctgctgac ttctttaaag cacaagaaga
     8641 agcgactaac cttccataca tctacctaag tgcaggtgta tctgctaaat tgttccaaga
     8701 aacattgcaa tttgctcacg actcaggtgc caagtttaat ggtgtgcttt gtggacgtgc
     8761 tacttgggca ggatctgtag aaccttacat caaagaaggt gaaaaagcag cacgtgaatg
     8821 gttgcgtact actggattcg aaaatattga tgaacttaac aaagttcttg ttaaaacagc
     8881 tagtccatgg actgataaag tatagtaaaa acataaaacg gaggatattg ttatgaacag
     8941 agaagagatg actctcttag ggtttgaaat tgttgcttat gctggagatg ctcgctctaa
     9001 acttttagaa gcgcttaaag cggctgaaaa tggtgatttc gctaaggcag atagtcttgt
     9061 agtagaagca ggaagctgta ttgcagaggc tcacaattct cagacagcta tgttggctcg
     9121 agaagcttct ggggaggaac ttccatacag cgttaccatg atgcatggtc aggaccactt
     9181 aatgactact gtcttattaa aagatgtgat tcatcacctc atcgaacttt ataaaagagg
     9241 agcaaaataa tgcataaact cattgaactt attgagaaag ggaaaccgtt ctttgagaaa
     9301 atctctcgaa acatctatct tcgtgctatt cgtgatggat ttatcgctgg tatgccagtc
     9361 atccttttct catctatctt tatccttatt gcctatgtcc caaatgcttg gggattccac
     9421 tggtcaaaag acattgagac cttcttgatg actccttata gctattcgat gggtatccta
     9481 gcattctttg ttggtggtac taccgctaaa gctttgacgg actcaatgaa ccgtgaccta
     9541 cctgcgacca atcagattaa cttcttatct acgatgctag cgtctatggt agggttcctt
     9601 ttgatggcag ctgagcctgc aaaagaagga ggcttcttga cagccttcac gggaacaaaa
     9661 ggtcttttga cagcatttat tgcagccttt gtgacagtta atgtttacaa ggtctgtgtg
     9721 aaaaataatg ttactattcg tatgcctgaa gaggttccac caaatatctc tcaagtattt
     9781 aaagacttga ttccattcac tgtagcggtt gttctccttt atggatttga actcattgtt
     9841 aagggaactc ttggtgtaac cgttgcagaa tcaatcggta cccttcttgc tcctctcttc
     9901 tcagctgcag atggttacct tggaattaca cttatctttg gtgcttatgc cttcttctgg
     9961 tttgttggta tccacggtcc ttcaattgtc gaaccagcaa tcgctgctat cacttatgcc
    10021 aatatcgatg ccaacttgca tcttatccaa gctggacaac atgcagacaa agttatcact
    10081 tctggtactc aaatgtttat tgttaccatg ggtggaacag gagctacatt gattgttcca
    10141 ttcttgttca tgtggatttg taaatcagaa cgtaaccgtg ccatcggacg tgcctcagtt
    10201 gttccaacat tctttggggt taatgagcca atcttatttg gtgcaccaat cgtattgaat
    10261 ccgattttct ttgtaccgtt cattttcgct ccgattgtca acgtttggat ctttaaattc
    10321 tttgttgaca cattgaacat gaactcattc tctgccaacc ttccatgggt tactcctggt
    10381 ccgttgggaa ttgtactcgg tactaacttc caagttctat catttatctt agccggactc
    10441 ttggtagttg ttgatactat catttattac ccatttgtta aggtatacga tgaacaaatt
    10501 cttgaagaag aacgttctgg taaaacaaac gatgctctta aagaaaaagt agctgcaaac
    10561 ttcaatactg ctaaagcaga tgccgttctt ggaaaagcag gcgttgctaa agaagatgta
    10621 gcagcaaaca ataatatcac aaaagaaact aatgtccttg ttctttgtgc aggtggaggt
    10681 acaagtggct tgcttgccaa tgccttgaac aaagcagcag cagaatacaa tgttccagtc
    10741 aaagcggcag cgggtagtta cggtgctcac cgtgaaatgt tgccagagtt tgacttggtt
    10801 atcttggctc cacaggtcgc ttcaaacttc gatgatatga aggctgaaac ggataaattg
    10861 ggcattaaac ttgcaaaaac tgaaggagct caatatatca aattgacacg tgatggacaa
    10921 ggtgctcttg catttgttca acaacagttt gattaataaa tttgtaaaag ttatttgaga
    10981 cgagattatt ctttcaattc cttataatat tgttaaccat atcattgcat ttcatttcct
    11041 tggtttccgg aactcagaat atcgtctcaa atgctttttt tgaaaggatt tatagttatg
    11101 actaaaacac ttcctaaaga ttttattttt ggtggtgcta cagctgctta tcaagcagaa
    11161 ggtgcgactc acacggatgg taaaggccca gttgcatggg ataagtatct tgaagacaat
    11221 tattggtaca cagcagagcc tgcaagtgat ttttaccata aatatcctgt tgatttagaa
    11281 ttagctgaaa aatatggcgt taatggtatt cgtatttcaa ttgcctggtc tcgtattttc
    11341 ccaactggct atggcgaagt aaatgaaaaa ggtgttgaat tctaccataa tctttttgcc
    11401 gagtgccaca aacgtcatgt tgagccattc gtgactttgc accactttga cacaccagaa
    11461 gttcttcact cagatggaga tttcttaaac cgcgaaaata tagaacactt tgtagattat
    11521 gccgctttct gttttgaaga gttcccagaa gtaaactact ggacaacttt caatgaaatt
    11581 ggcccaattg gagatggtca atacttggtt ggtaaattcc ctccaggcat tcaatatgat
    11641 cttgccaaag tcttccaatc acaccacaat atgatggttt ctcatgcacg tgctgtgaaa
    11701 ttgtataaag ataaaggtta taaaggcgaa attggtgtag tacatgcgtt gccaaccaaa
    11761 tacccttatg atccagaaaa tccagcagat gttcgtgccg ctgagttaga agatatcatc
    11821 cataacaaat ttatcttgga tgcaacctac cttggacact attcagataa aacgatggaa
    11881 ggggtcaacc acatcctagc tgaaaatggt ggagaacttg atcttcgtga tgaagacttc
    11941 caagcacttg aagcagctaa agatttgaac gatttccttg gtatcaacta ctacatgagt
    12001 gattggatgc aagcctttga tggtgagact gaaatcattc acaatggtaa gggtgaaaaa
    12061 ggaagttcta agtaccagat taaaggtgtt ggtcgccgaa tcgcaccaga ttatgtgcct
    12121 agaacggatt gggactggat tatttatcct gaaggcttgt atgaccaaat catgcgagtg
    12181 aaaaatgatt atccaaacta caagaagatt tacatcactg aaaacggtct tggatacaaa
    12241 gatgagtttg tagataatac cgtttatgat gatggtcgta ttgattacgt gaagaaacac
    12301 ttggaagttt tatcagacgc aattgcggat ggtgcaaatg ttaaaggtta cttcatctgg
    12361 tcacttatgg atgtcttctc atggtcaaac ggatacgaaa aacgttatgg actattctat
    12421 gtagactttg acacgcaaga acgctatcct aagaaatcag ctcattggta taagaaagta
    12481 gcagaaactc aagtgataga gtaatattac ttgaaaatgt aaaaaattgt tatccgatac
    12541 tttagaaaaa gtacaacact tatttagacc aggctttgaa aaggtatata ttgttagttt
    12601 cgaagattgt cctatgattc ctgagcttga agctaccccg ttgctaaaat gtggtaaatg
    12661 gtatgtttca actggaaaag agtggatttg ccattctgat ttagagttat cagcatttga
    12721 atgggaattt ttacaatcac tcgatgtaga aatacgtgag actattcact tcgaggtaaa
    12781 ttatttgcct ttccaataat aaaaagaaag gaattagttg tgactatcga attaaaaaac
    12841 gagtatctta ctgttcagtt taaaacactt ggtggtcaac tgacttcgat taaagacaag
    12901 gatgggatag agtatctctg gcaagctgat ccaaattatt ggaatggaca ggcgcctatt
    12961 ctatttccta tctgtggtag tttacgaaat gattgggcta tttatagacc tcaagaaaga
    13021 ccctttttta caggtcttat tcgtagacat ggttttgttc gaaaagaaga atttattctg
    13081 gaagaagtca atgataatag cgtgaccttt agtattaaac caaatgctga gatgcttgat
    13141 aattacctat atcagtttga actgagagtt gtttatacct tgaatggtaa atcaattaga
    13201 accgaatttc aggtaacgaa cttggaaatg gaaaaaacaa tgccttactt tattggagcc
    13261 catccagcat tcaatagtcc tttagtagaa ggtgaaaact atgaggatta ttatattgaa
    13321 tttagtgagg ttgagtcttg ctcgatacca aagagttttc ctgagacagg attattagat
    13381 ttgcaagatc ggacaccttt tttggaaaat caaaaaattc tcgatttgga ctactcactt
    13441 ttttcccatg atgccattac acttgaccag ctcaagtctc gtagcgtaac gcttcggtca
    13501 aggaagtctg gtaaaggtct tcgagtagat tttgatgatt ttccgaactt gattctgtgg
    13561 tctacaacta ataaaagtcc attcattgct ttggaacctt ggagtggtct ctccacttca
    13621 cttgaagaag gtaatttctt agaagataaa agacaggtaa cgaaaatttc acctcaagaa
    13681 acttctagaa aaatctatga tattactatc cttaattaaa atttgttatt atttgagtct
    13741 tcaataagat ttgaatactc ttaccttgtg atgatagatt ggtcttctcc gtgccagtct
    13801 tacatcgcaa ggtttttaag ttttttgtgg gtctatgtca actgtagtgg gtgacgaaaa
    13861 gctaatatct aaagacagtc tggtagtaaa aaataagatt atttactact tcttgattta
    13921 aaataatagt ggagccatta atttgtggca aatttaattt aatattttgc ctcaaattag
    13981 ccacactttt tatagaacta agaggaaaaa tgaaattttc ttcctattaa tatagttgtt
    14041 tgaaatctta aatatagcg
//
LOCUS       DAFEEZ010000076        13346 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000076
VERSION     DAFEEZ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.079"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(45..1364)
                     /locus_tag="LP245_002410"
     CDS             complement(45..1364)
                     /locus_tag="LP245_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1520294.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="LP245_002411"
     CDS             complement(1361..2014)
                     /locus_tag="LP245_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1520295.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..2822
                     /locus_tag="LP245_002412"
                     /pseudo
     CDS             2302..2822
                     /locus_tag="LP245_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2724..3440)
                     /locus_tag="LP245_002413"
     CDS             complement(2724..3440)
                     /locus_tag="LP245_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBL1520296.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(3564..3749)
                     /locus_tag="LP245_002414"
     CDS             complement(3564..3749)
                     /locus_tag="LP245_002414"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520297.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            3976..5249
                     /locus_tag="LP245_002415"
                     /pseudo
     CDS             3976..5249
                     /locus_tag="LP245_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5356..6387)
                     /locus_tag="LP245_002416"
     CDS             complement(5356..6387)
                     /locus_tag="LP245_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1520298.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6394..7224)
                     /locus_tag="LP245_002417"
     CDS             complement(6394..7224)
                     /locus_tag="LP245_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1520299.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7221..8036)
                     /locus_tag="LP245_002418"
     CDS             complement(7221..8036)
                     /locus_tag="LP245_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL1520300.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8033..8857)
                     /locus_tag="LP245_002419"
     CDS             complement(8033..8857)
                     /locus_tag="LP245_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBL1520301.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8847..9947)
                     /locus_tag="LP245_002420"
     CDS             complement(8847..9947)
                     /locus_tag="LP245_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL1520302.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10125..10910
                     /locus_tag="LP245_002421"
     CDS             10125..10910
                     /locus_tag="LP245_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HBL1520303.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10943..11326
                     /locus_tag="LP245_002422"
     CDS             10943..11326
                     /locus_tag="LP245_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL1520304.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11402..11533
                     /locus_tag="LP245_002423"
     CDS             11402..11533
                     /locus_tag="LP245_002423"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1520305.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11502..11738
                     /locus_tag="LP245_002424"
     CDS             11502..11738
                     /locus_tag="LP245_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL1520306.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(11816..12787)
                     /locus_tag="LP245_002425"
     CDS             complement(11816..12787)
                     /locus_tag="LP245_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBL1520307.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         4055 a         2912 c         2306 g         4073 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tgttgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact gaagcaggcg
     2641 attctcatag aactgtacga aaatcaatca cgtaatctga aaatcagaag aagtaccgtc
     2701 ggctcaagcg atattggaaa ctcttactca aagattccac gacattggag ccgctcaaac
     2761 ggcattatca tcgactgttt aaacgaccaa ttagtcaaac agaaatcgtc gatgaaccgt
     2821 tgtgcacaat ggtgtcctga acgtacagcg acaccttcca tatccagagc agtcgccaca
     2881 tcacggggat ggatgccatc caaattaaaa gcaaccacgc cagtatgatg ttcaggatct
     2941 tgcggtccgt aaatggtgat accgccgatc gcttgtaatt taggtaaaac gtaggcaacc
     3001 agttcttgct cataacgatg aatattctcc ataccaatct cattcaagta atcgattgct
     3061 cctgcaatgt tcggagtacc agcttcaaat ttccatggca gctctttcca tgaactatcg
     3121 taaagattga caaaatctat catttcaccg ccgaattcga ctggctccat ttgttctaac
     3181 aattgacgtt tgccatataa tacaccgatt cctgtcggcc cgcacatttt atgcccgcta
     3241 aaggcgaaaa aatctgcatc caacgcttgt acatcaactg tcatatgcgg tgctgcttgg
     3301 gcaccgactg gactatcctc aactacaaca gcctgttcaa ccctcagccg tttcaagcac
     3361 aacaaataac cttctggatc tggtttgccg acctgaagat catcgatcgt cacaaaggaa
     3421 tcaatttttt ccttaatcat cggatgtgct tcaaaaaaat agtctagctc ccgcagttca
     3481 gaattgagac tactccgatt ttccagtgct gctgatccgc tgctcaaaat gttcagcatc
     3541 cactggtctc ccaaccgctt gacttatccc ttcataaaag gacagttctg ctgccgtccc
     3601 aacaccttgt tgatagtctg caaaaggaat tttatagccg aactgctcca gtaaataggc
     3661 ttcagtaaat agtgatgaat actctcgtaa aacatccatt cactgtcaat catcgtccca
     3721 tcaaaatcaa aaataagtgc tttggtcatc ttctttcccc cttacccaaa acaagcaaaa
     3781 gctgtgtcct gctctctcta cagtatcagc ataaaaactg ccgtctgaaa agtcaaaggt
     3841 gaaagaaatg tggcgctata atttctagga ctgatagtaa atcattctat cagtcctttt
     3901 gagcataaaa aaacaaaaca tacagaagct ccgttagaat tgaatcacca caacacaatc
     3961 aaaggagcgt tctgtatgcc tgatcttcat cttatcaaac tattactagg aatcaaagat
     4021 ggaaacattc aaatcactca tgtcgagaag aaaaaaatac attcaatcaa cagtatcgtt
     4081 gtttctgcca cgctcattaa aacgattcag ccctgtcctc agtgtaaaca ggtgaatcaa
     4141 catgggctga tcgttaagaa cggaaagaaa aaatcgctgg tccttctcaa taagtgtgcg
     4201 aatcaacgga cttatcttgc tttggcaaag caacggtacc tctgtcgtgg ctgtcacacc
     4261 tattttacgg cgaataccta cattgttgaa aaaaactgtt ttatcgccaa acaagtacat
     4321 tataaaatat tggaggaatt gactgaaaaa caagcaatga cgacgatttc taaacattgc
     4381 ggcgtttctt ggtcaaccgt ttcgcgaaca ctcgcttctc tgctccccat gacaaacgtg
     4441 aaaataaatt ggttgcctcg ctgttcattg gtagatgaat ttcgttcatt gaaaaatcaa
     4501 gtcggtccct attctttttc ttgtatggat ggcgatactg ggaaattact ggatattctt
     4561 ccttcacgta agaagaaaga tctcatttct tattttatgc aatttgaacg acgtgcacgt
     4621 ttaaacgtaa aaatactcgt aacagatatg aacgcctctt atgctttgct gataaaagag
     4681 tgctttcctc atgccaaact cgttgtggat cgctttcaca tcgtcaagca cctcattcgc
     4741 agttttaagg atatttgact atgagtcatg aaaagcttcg accgaaacga tccaatacaa
     4801 gccaaacact atcgacaagt gaaggcttta tctcgacttc tgatcaaacg acaggacacg
     4861 cttgtttatg ataaatggac aaaatggcgt aattttggtt gggcctattt aaccgaaagt
     4921 gaagtcgtag aacgtctact ttctacttct gatgaactac gaatagctta tgcttactat
     4981 caagaaattc ttcaagcttt ttatgacaaa gaagcggaca tcttctttca gcttgtaaaa
     5041 acaatgccca agtcggttcc aagagaactg catcatataa aaaaagcgtt tataaactat
     5101 gaatccggca ttcgtttagc cttagagttg ccttactcaa atggcaaaat agaaaatctg
     5161 catacccaca tcaaagcatt gaaacgaata gcttacgggt taggatgaga accagaattt
     5221 tcttaatcaa tcatctgatc acttattaaa cataaaaaaa catctaaagc agaaaatcaa
     5281 ttctacctta gatgttctta tatcactcta tcagtcctat ttgacaaaga gccagaaatg
     5341 tttgccgact atacactagc tttgttgtgc aaaatgctga gtatcaattt ccacagggat
     5401 tgctagaata tctttcagct gaatgtataa ggcatcgcta attttctctt cccgatcgtt
     5461 caaccgatcc actaaaattt ctttgccctc cagcgtttga aaaacatacc gttgaatgtt
     5521 gcctaaaata aatgattcct tccatagaac cggaatctta accccctgag gaaccggttc
     5581 aaattgaatc agctccggtc ttaaataata aatgcagcga ttgcccttag cggaaaactc
     5641 gtgggtatac tgattcagct cataccattc gaaacgatta tagttgccga taaattccgc
     5701 aacaaatcgg ctctgaggat tctgatacaa ttccttcgag gtggaaacct gagccacccg
     5761 cccagcttcc atcacaaaaa tccgatcact gattcgcatc gcctcttctt ggtcatgagt
     5821 cacaaaaatc atcgtcatcc ctagcgattg ctggatagcg cgcaaatccc gctgcagctg
     5881 ttttctaatt cgggcatcca aagcacttaa tggctcatcc agcagcagga ctttcggttc
     5941 agtgaccaat gagcgagcca gtgccacccg ttgtcgttga ccgccagaaa gaaactggac
     6001 atttttatct gcctgctccg tcatatccac caatgatagc atctcaaaaa ccttttcctg
     6061 aatcacctca ggactcagct tctttacctt caaaccaaag gctacatttt caaaaacagt
     6121 catagttgga aacaatgcat actgttgaaa aacaaagccg atattgcgat ccttcgtagg
     6181 cttatcggca atattctcat tgtccagcac aatctcaccg ctctttggtt gttccaatcc
     6241 cgtgatacag cgcagcaacg tagactttcc gcacccgctg ggacctagta aagtaaccag
     6301 ctcacccttt tcaatctgaa tttcatcaat agctaaaatc tgtttttcat caaaaaacag
     6361 attgagatca tgtatttcta aaaacatttt ccgtcacaac tcctttaagg gcttcttttt
     6421 cgactgcttc tcttccctcg tctgcttaag ggacagctgt tgcttttgtc gataagtcag
     6481 cataaaggta gttaaagcaa ttcccaccat aaacagcaaa tacaaaacca tcacagcgct
     6541 agccaaatgg ccgttttcgt tcatccgccg cagcatatag atgcgtaccg tctgaaatcg
     6601 accgccaatc aacaggttcg tcagcatgta ctccccaaaa accgaagaaa aaatcatcag
     6661 agaaactagg gtcacaccga tacggatgtt tggaaacagc acctggataa taatcgtaga
     6721 catcggggcg cccaaggttt ctgctgcatc cactaattcc ttcagattaa ttaagcgcat
     6781 ctggttgtta agactaagat agacaatcgg caacgccgta ataaacaatg cacctaccaa
     6841 cactacaaac attgggatac cagtttcagc atacgttcga agcaaagccg ttaccaaaat
     6901 cactcctggt aaagcatacg gcagcaggag cagcttttcc agccaacgat tcaaacgagg
     6961 gaaatacaaa tgaatccaaa taatggtggg aatcatcaac aacagaatcg tcaccaagac
     7021 cacacctgct aataaaagtg agcgacccac cgcagcaata aattccctgt ccgtcagcag
     7081 ctgttggaac cattgcaagg taaaatcact aggtaaaagc gattttgacc atttagtgga
     7141 gctggcatac aaaatcgttc caataatcgg cagcaagtaa tacaggacaa agcagaacaa
     7201 aatcggtttt attaactttt tcacgtctgc accaccttgc ctttcttttg aataatcaac
     7261 attgccgtta ccagcaggac acctaaagcg actgccaacg cactgcctaa attaggcttg
     7321 gcgaacacat ctcccgacac taaagccgca attcgaatcg ttaaaagatt tacattactg
     7381 ctggtcaggg catacgctgt ttcataggtc cccatgccat tagcaaataa gatgacaaag
     7441 gtgctggcaa tcgatggtcg caaaaaaggc aaagccacct tgaaccaagc atacgctgat
     7501 gaagcgccca gcaattgtgc ggactccagc cattcctttt tcacttcctt catgctggga
     7561 tacaaaaaca agacccctaa cggaatttgg aaataggtat acgtgatggt caatccccac
     7621 caagaataca aattgaagtc cgctagaaat ggcaaaatca ttttcagcac acctacattc
     7681 cccaacaaaa taataaaaga gaatgccagc ggaatcccag caaaattagc tgccaaattg
     7741 gaaacaaagg tgattttctc ctgcaattta gtcgatagat tcattaagca taaacataaa
     7801 ataaacgtcc cgattaaccc aatcacactg gagctgacag caatcagtac gctgttaaca
     7861 aaggcctgtg tgtaatattt gttgctgaaa atatcactgt aattggccaa tgtccactgg
     7921 ttagttaaat cactgtgcaa gctgcacaga accataaaaa gcagcggcag cagtaaaaat
     7981 gcacagaaga taaaggaggc aggaaccaga accaagcgtt ttttcatctc tttcatcccc
     8041 tcatcaattc ttgaatgtcc tgcattttct ctgacggtgc aattcctaat aaccagcaaa
     8101 acaatggagc cgccagcagc tgtggtacag tttgttcctt cagcttttgg cgtttatttg
     8161 aaatcaaata aaaaggaact tcacgatgtg cagccaagct gccgccatgc agtccgtgcg
     8221 catccatccc gtgatccgca gtcaccacga cttgataacc tttttgcagc cattcaggaa
     8281 ggtaaatagc caataatctg tccgcctgat taaccgctgc tgcatattca tgagaatcgg
     8341 cggtaaattt gtgaccgaca tcatcaatat tcatcgaatg tacgaccaaa aagtctggct
     8401 gatactgatt cactaaataa tgggcatccg caaataaatg cgaatcaggg taagtgtcct
     8461 cactataaaa gatgccatgc tgaatcagtc gctcctcctg atgctggatg cgatcaacca
     8521 aacgattata gggggcttga ttgtacaact cgctgtacca gtggtaagcg gcggctcctg
     8581 tttttccgcc agcttcctta actaattcaa acagcgacca ctctttggat cgctgagcat
     8641 ggtaattact atagatgcca ttttcatagg ctggaacgcc ggtcatcagt acttcgtata
     8701 acggacgtga attgctgggc agctcacttt ttaccttcaa taagcttgct tgctggtgct
     8761 caactaaatg attcatgaac ccaagctggg cgacggctgt gtcgtagcga cagccgtcta
     8821 gtataactac aatcagtttg tcaagtctac tttgcatagg tcagtacctc cgcctgccaa
     8881 agctctggaa gctctacaga ggtcttgttc caagcttcat tgtcttcaac tggcaccgcc
     8941 gcttcataag catcctccgg cagtaatttt tcagctactt ctttaggcag ctctaccttg
     9001 cgaataggtc gcgcatagcc ctttgccaaa ttgatttgcc cttcatcaga taaaatatat
     9061 tcccgtgcta gctttgccgc attgggatga ggggcatttt tattgattaa ggttgtatac
     9121 ccgctaatga tggagccgtc tgttggcaca gttacctcaa aacgctcgga gtcaatttgg
     9181 tcacgataat ttagtccatt gaagtcccaa acaactgcca catcgatttc acctttttca
     9241 agatttgcta cgctggcatc aacggtggac aaacggcctt tttctgccat ttttttgtag
     9301 taattcagac ctggctgaat atccttttcg tcacctccgt tggcaatcgc cgcagccaat
     9361 acagcaaatt gtgcttggtt ggcaatcgtc acatccccca cgctaacttg atagtcaccc
     9421 tcttgcagct ccttccagct agtcggtgct tgcttcacat tctctttatc ggtgataaag
     9481 gaaatggttc ccgtatagct taacaaccaa tccccatcat catcctttgc ccaatccgga
     9541 atttcctccc aatagttggt cttataaggt aaggttaact ctttgctttc agccaacgga
     9601 ccgaagctga taccgacatc accaatatcg gcggttccat tttttccttc tgattcaaac
     9661 ttagccaatt cttctgcact ggacatatcc gtatccacgt gacttaagcc gtattctttt
     9721 tcaaggtcgt tccaagtgcc tacccaattt gcccaagtat ccggcattcc caagctggca
     9781 atctctcctt cttccttggc tttttctata atcgtatcta aagagtcgtc tgccgcagcc
     9841 gattgcttcg ttgcttcacc tgagccgcag cctgtcagca ggatacttac tgttgctgca
     9901 caaaataaac cgatagtcat gttacgaatt ttttcattca ttttcattca ttcttctccc
     9961 ctttcgataa ttccattcta acaaagcttt gtaatgagag aatcagtttc ttgaaaaggt
    10021 ttcatgaaca atgtaaaggt tgtatatggt ttgtaaattt cgacgaattc ccgttaacct
    10081 tctaaagctt ttgcggtatg atagtagaaa aaaggaggct ccctatgcag tattatgatc
    10141 agcatctcca cacgtatttt tcctttgatt cagaggaaaa atttgaaaac tatttagcct
    10201 atcagccgga gtttttcgtt tctacggatc actttgattt aaacaatcca tctaccggaa
    10261 aagatgacat tccggattat ccagcctata taaacaaact ggactcttta aaagaaacct
    10321 attccaccaa atttctgcga ggtatcgaga ttggcgttgt tccaggacaa gaagagcgga
    10381 tcgtggatta cctcgctcag catccttatg atttaaagct ggtaagtatt catcaaaatg
    10441 gccgctttga ttatatggac gatgtggttt taaccaaaga tcccattcaa actaccaagg
    10501 aatattttga tcagatgttg caggtcttga cggattttcc agaaggagat attttgactc
    10561 actttgatta tggattacgc cgcttcacct tcacagcgga agaattcgcg gagcattttg
    10621 aggctcagct gctaacgatt ttcaaaaagg ttgttgaacg agaattggcg atggagttaa
    10681 atgccaagag cttcttgaaa tacggcaacg aagaccttta ccgttatgcc gttcctttgt
    10741 atcaaagtgt cggcggaaag ctctttacct taggctcgga tgctcatgtt gccgaagatt
    10801 atcagctggg ctttaaaaaa atgagtcagc tgttggcaga ctgtcaggta gaaaagttgc
    10861 tagtcattca aggaaaagaa cgccgcctga cgccgctgcc gattttgtga ttcctatata
    10921 atagaagaaa gtggtgaaaa aaatgagcaa cctgtgggac tacaatcaag aggcacccat
    10981 ccattattta attgcgcgac attgggatgc gttgaaaatt gaggcggttt gccgatcctt
    11041 gttagcagcc gttccaaaac aacaactgga aaattttttg gtggctgaca gcttgcagcg
    11101 ggaaaaagtt caggcttatt ttgcagcctt taaagatcag cctttggaat atttgcatgc
    11161 gcagtttcat cttttttatc aagtagccgc cccagatgac tacaacgatt tacgaggaca
    11221 gctgcaattg acctttcaag cggatgaaac cgcctatacc gttttattgg gaatggctcg
    11281 ccttggtgat caggcgaagg tcgagtggcg gattttcgat atttgatggc aggatcaagg
    11341 cgtttcagtt gcaaaccttc ctctctttca attagaaaaa ccgcagcagg aagaagtttg
    11401 tgtgctggtc accgatgctg gtgaaattcg tctccgctta tttcctgacc aagctcccct
    11461 ggctgtagcc aactggcgct ccctagctga gcaaggcgtt tatgacaaca cacctttcgg
    11521 ctcgtgtcat taaggaattt gttattcaag gtggcgcttt ggatggttct ggtgatgaag
    11581 ctgtttccag ctatgagggc tttttcgctg atgaagtgca tcgcggactt tatcatttta
    11641 atggcgcctt ggccttaggg gaccacggcc cccacaccaa cggcaaccag ttttttattg
    11701 tgcaaaacac aaaggcgcag gctgacctgc taatgtaaag caagcatact tggagcttgg
    11761 aggactaccg gagctggatg gtcgttatac tgtttttgga caggtatacc aagggttaga
    11821 aatcgtagca gcgatcgcag ctcagccgac aaacagtgaa gatgtaccga ttgagccagt
    11881 gttcattcga caaattaact tcgaaaaaac atcgtaaaaa gacactcact gacttcagca
    11941 aaagctctat tcttgagctg gctgcagcta gtgagtgtct ttcatttatc cataagataa
    12001 agcttggatt caataaataa ataaatgttt tggttaaagc tgtgaccagc aaatgaggaa
    12061 ccgtgcgagc cagttgatct gccaatgcaa acatttcttt aggtgaaggc gctggcgtgt
    12121 ctgccaacgg atactccagt cccaatgctt ggtaaccgtg cataccatag cagtggtacg
    12181 gtagtaattc taacggtacg aaccgatcaa gatctgccac aaaacaagca atcgtcagca
    12241 gctcggtcag gttcatattg atacctggaa ccacaggaac tcgaattcgc acttcgcagt
    12301 taggatactc aattaaaaag cgacgaatat tcttcaaaat ttgttggtta tctaagccgg
    12361 tccattgttt gtggagcttg ctggtaaaca tttttacatc cacaaacaat gtatccacat
    12421 agggagctac cttttggatt tcattataag caccacaaaa gctggtttcc agtacggtat
    12481 tgattccaat gtatttcgat ttttgcaaaa tttctttagc aaaatccgcc tgaaccagtg
    12541 cctcgcctcc gctaatggtc actccgccat ccgagtgaaa gtaaaaaaca gcatccttct
    12601 caatctcatc cattacctct tcagcggtca tggtctggcc aaatcctttt tcaatctgct
    12661 tgctttgtga ttcgggaatc gaacaccagg cacagcgtaa tgggcagccc tttaaataaa
    12721 caacggtccg taaaccagca ccatcatgta gagaaccctg ttctattctt aatactgttc
    12781 cttccatata gatttttgaa ttacacacta gtttaaacta aaacacacaa ggaaaaactt
    12841 accatttaat cataaaatta gctcatataa atatactagg atgtaaaata gactggtcaa
    12901 aatctggtca aaaaagagga ctaatacagg tagtcctctt ttttgttatt ttaatattct
    12961 aaatcatttt ttattggttt attcccttat tcgatgtaga ctcaaatcac tatatcacta
    13021 gatatcaaac ggcgtcatac ggaatcaaaa acatcaaatt tgacctgtta aatggtcatt
    13081 gaataacatt caaaatcaat aaaacggagt cagacacgga gtcaaaaacg ctgagagtaa
    13141 aaaatatata cagccttgta ggtaaagtac cacagggctg tatatttttt atttcagatt
    13201 accttaaatg attccattta ctttttatct cattttttcc tactagttag tatcaaatac
    13261 tctcctattt tctcaataaa ctatttttgg atacatggta tctgaaacag ctaaaacctt
    13321 gtcattacag caaaaaatca cgttat
//
LOCUS       DAFEEZ010000077        13145 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000077
VERSION     DAFEEZ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.080"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(77..149)
                     /locus_tag="LP245_002426"
     tRNA            complement(77..149)
                     /locus_tag="LP245_002426"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="LP245_002427"
     CDS             530..1099
                     /locus_tag="LP245_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBL1520308.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="LP245_002428"
     CDS             1086..1946
                     /locus_tag="LP245_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL1520309.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="LP245_002429"
     CDS             2136..2840
                     /locus_tag="LP245_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1520310.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="LP245_002430"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="LP245_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBL1520311.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="LP245_002431"
     CDS             4677..5993
                     /locus_tag="LP245_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520312.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="LP245_002432"
     CDS             5994..6863
                     /locus_tag="LP245_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBL1520313.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="LP245_002433"
     CDS             6918..7727
                     /locus_tag="LP245_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL1520314.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="LP245_002434"
     CDS             complement(7830..8459)
                     /locus_tag="LP245_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBL1520315.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="LP245_002435"
     CDS             8629..9921
                     /locus_tag="LP245_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1520316.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="LP245_002436"
     CDS             complement(9997..10659)
                     /locus_tag="LP245_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL1520317.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="LP245_002437"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="LP245_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBL1520318.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="LP245_002438"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="LP245_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBL1520319.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4369 a         2264 c         2833 g         3679 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt tttgtgtgta
    13081 attataatga aaatagttat ttttaatagt tataatattt tatctattaa aagtaaatat
    13141 ccatt
//
LOCUS       DAFEEZ010000078        12604 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000078
VERSION     DAFEEZ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.081"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(10..159)
                     /locus_tag="LP245_002439"
     CDS             complement(10..159)
                     /locus_tag="LP245_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520320.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            555..755
                     /locus_tag="LP245_002440"
     CDS             555..755
                     /locus_tag="LP245_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1520321.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            1323..1886
                     /locus_tag="LP245_002441"
     CDS             1323..1886
                     /locus_tag="LP245_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520322.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1947..2291)
                     /locus_tag="LP245_002442"
     CDS             complement(1947..2291)
                     /locus_tag="LP245_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520323.1"
                     /translation="MISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFHYSPYRLF
                     QYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHDEVYLAEC
                     LANLEQKGIYLT"
     gene            complement(2388..2633)
                     /locus_tag="LP245_002443"
     CDS             complement(2388..2633)
                     /locus_tag="LP245_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1520324.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(2703..2957)
                     /locus_tag="LP245_002444"
     CDS             complement(2703..2957)
                     /locus_tag="LP245_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520325.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(3121..3444)
                     /locus_tag="LP245_002445"
     CDS             complement(3121..3444)
                     /locus_tag="LP245_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520326.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            3631..3704
                     /locus_tag="LP245_002446"
     tRNA            3631..3704
                     /locus_tag="LP245_002446"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3665..3667,aa:Ile,seq:cat)
     gene            complement(4089..4586)
                     /locus_tag="LP245_002447"
     CDS             complement(4089..4586)
                     /locus_tag="LP245_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL1520327.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(4626..5435)
                     /locus_tag="LP245_002448"
     CDS             complement(4626..5435)
                     /locus_tag="LP245_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL1520328.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIDMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            5769..6626
                     /locus_tag="LP245_002449"
     CDS             5769..6626
                     /locus_tag="LP245_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBL1520329.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            6619..7521
                     /locus_tag="LP245_002450"
     CDS             6619..7521
                     /locus_tag="LP245_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBL1520330.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            7554..7904
                     /locus_tag="LP245_002451"
     CDS             7554..7904
                     /locus_tag="LP245_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL1520331.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7953..8883
                     /locus_tag="LP245_002452"
                     /pseudo
     CDS             7953..8883
                     /locus_tag="LP245_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
     gene            8961..9854
                     /locus_tag="LP245_002453"
     CDS             8961..9854
                     /locus_tag="LP245_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1520332.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9892..10455
                     /gene="amaP"
                     /locus_tag="LP245_002454"
     CDS             9892..10455
                     /gene="amaP"
                     /locus_tag="LP245_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBL1520333.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            10469..10657
                     /locus_tag="LP245_002455"
     CDS             10469..10657
                     /locus_tag="LP245_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBL1520334.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            10670..11572
                     /locus_tag="LP245_002456"
     CDS             10670..11572
                     /locus_tag="LP245_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL1520335.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            11604..11846
                     /locus_tag="LP245_002457"
     CDS             11604..11846
                     /locus_tag="LP245_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL1520336.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(12102..12473)
                     /locus_tag="LP245_002458"
     CDS             complement(12102..12473)
                     /locus_tag="LP245_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520337.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4464 a         2114 c         2367 g         3659 t
ORIGIN      
        1 ttccactcct tatgcagatt tttttaattc ttgcactgct tgttcgatcg taacacctgt
       61 cgctacatga ttggtatttt ctttgtcaaa aacgacaaat agattcaaat ctgtatccaa
      121 ggttactcga tattgtatat ctttgttata gaatgtcata gccattctcc tttctttaaa
      181 tacttgctga aaggcaacga acgcgttgat aacgaaattc catttataag tataccacca
      241 attgaaaggt tttcatagtt aagaaatttt aaagtcaaaa gttgcagata aaagcaaata
      301 aacaagaaaa caaaaagtga atcaatcgcg gttattcaac tttttcttcg attcgaagac
      361 aatagaagac aatgaatttt atatttcatt gcattatcct tgtgttatta gaaaaagcat
      421 gatatattaa atgagtaatc tattttgaaa cgtaatttga gcgatatatc tacatagata
      481 aaactccttt tgcctatcaa atatttattg caacgaaaaa acgtacattg atacgtatca
      541 ggaggaattt atttatgaat aacggtacag taaaatggtt caacgcagac aaaggttttg
      601 gctttatcac tggtgaagat ggaaatgatg tatttgcaca tttttcagct atccaaggtg
      661 acggcttcaa aactttagaa gaaggccaag cagtgtctta cgatgttgaa gatggtcaac
      721 gtggccctca agcaacaaac attgttaaag cttaataaaa attgactttt aaccgtcttt
      781 tcgaaagaaa agacggtttt tttgtacgaa aaaattcatt ggtcgttgaa tgggctgaat
      841 agtagtgtat aaaacaattt tgtggagcgt gaagctttta tggtagagga aaatacgaat
      901 aaagtgatgt tgataaaaag attcctatct tgaatatgaa tcgagatgtc ttgaaaatga
      961 atgagtttga ccaatcatta tcctatcgaa atttacagtt tcgttcgatt ggtctgtcaa
     1021 ttaatgaaaa agtaaaaaag aatatgttct aggaagaggg cggcacatct aaatttttaa
     1081 gtaacggaca gttcaaatat caagcattga aagaggctat cctactgttt gaaggaatac
     1141 gaatatataa aaacgacaaa gaggaaaaag tagttcatta aatcccttca agtgatgaaa
     1201 gaatgagatc taataaaacc tgatctttca tctgtttttt taataacgta ataatttttt
     1261 tattttttgt gctttcgccg ttattgtaga gtgatttagc attcttattt ttaaaaataa
     1321 ctgtgttata tattaaaaaa ggcataatag ttataagctt ttttaaagaa tatttagaaa
     1381 ttattaattt tcgtctgaaa acaaaaaaag aaagcgttat tattttagtc tattttcagg
     1441 gggggaacct tatgataaaa aaactatttt tactatcaat attaacgcta gcaatggcag
     1501 gttgttctga ctctggctta gcaactgaac tgatcacaaa atcaactgaa gccacgacag
     1561 aggagttaaa atgtggaaac gatcacagtg actacagagg cttaaatcga cgatgcatgg
     1621 gaatattagg cagaagcaat tgtaagcatc gatgtagtaa tcgaagaagg tgtagaagaa
     1681 gcaacagaaa aatcaaaaga aagatcaaaa gaagcaatct gtgctgtgca tcgtatacag
     1741 acgtcgaaga tgcggtactt ttaaaccacg tcaggagatg ttcatttatg tctagggaag
     1801 ttggcgatga accaaaacta gagtacgctt ttagttttgc acgtgaggat gaagataacc
     1861 ctaaaactta cgacatttta gcttgatcta agatggttaa agctttttaa tgaagtaaga
     1921 ggagatagaa ggcttttcta gttatattag gtaagataaa ttcctttttg ctccaaattt
     1981 gctaaacatt ctgctagata aacttcatcg tgttccggat aaatcggcac gttgcgctct
     2041 acagtaggta aatcaaaaaa tgcttcgcat gatttgccac gatacatagg atttttccac
     2101 tctggtgctg ggctgtaacc acgtttttcc atttcatcca tgacaagctg atgatattgg
     2161 aataatctat aaggagaata gtgaaaaaca taatccacag tagcatgttt ctttccccag
     2221 ccatttcctc ttaatgcaca gcattcccga tgttgtccta aaagctgttg acgaggaagc
     2281 tttgaaatca atttttcatg ccataatcac atagaaatgt ctcctttata tatagattgt
     2341 taaccttaga cgttaaatga aaaaaccagc accaaggctg gaaaaaatca cttcagtttg
     2401 cttgctgttt ctgagcgacc aattaggtaa tcaacggaaa tatcgtaaaa gtcagcgata
     2461 tagattaatt caatgatgct tggaatttct tctccttctt cgtacttacg atatttgaat
     2521 aaaggaatac ttaacgcgct agaaacagct acttgagata aagatcggcc agttcttaag
     2581 aaattcagac gacaacgtaa agtatccagt aaaatagctt cttcgatact catttaatca
     2641 cctttcatta tagtagaata gttataatga ctatagaaag ctacacatgc aatcaatagt
     2701 actcaatgtt ttttatttaa acgtatcaaa taaagaatga cgatcaataa agacaaaacc
     2761 agtcctgata attcttctat aaaaacacta tcgggttcaa agtagttgta attaaaaact
     2821 ttccacataa agtagatagc cggaagagtc aaaatagcta aataaaaccg ttctttgttc
     2881 caattcataa gataaacaat acttgcgacc agtgcgaccg caggcaccca aaacaaaact
     2941 ctcaccaacg taatcatgta acggactcct caacgattca tataataaaa gataacatgt
     3001 tattgcatac atcacaaatg aaatgctagg aaaataaaag aagaatagat caatgaaaaa
     3061 tgaaaaagca gaacagtttt ctgctgataa gcaggaactg ttccgctgaa tgtgtcttat
     3121 ctatcgagaa aaaatcaatg gattgatatc taagtaattc aatacatata aaaagaggac
     3181 gatcgcattc actaaaaagg aaagaatgat gatcccatag cgaatggaaa catatttaac
     3241 aaatactttt gtttgaatac gggcatatct ttttccttta tagctgagca tcatgacaag
     3301 aagcaaaagg gtaatcacac cttgaaaaat cattccaata aacagaattc ctgaggtttg
     3361 ataatttaat tggagaaaat aagctgctgc cgcaactaaa tcgaataaaa tcgcaataaa
     3421 tggcaaaata atcactccta acattgagaa taaataaaag aataacattt tttctaaaat
     3481 aagcaaataa aaattaaagt aacaaaatag ttatgacaca agtaaaagaa ataagaataa
     3541 caatattatt ttacttatat tttgaaactt gtgagagttt gtcattcgtg ctatagttga
     3601 aaagtaacaa aaataaattt tatttatgat gtacctttag ctcagttggt tagagcagac
     3661 ggctcataac cgtccggtcg taggttcgag tcctacaagg tacataagag gttgtgaaaa
     3721 agctgccctg catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttact
     3781 tggctgttct tattactgca gatgcaagct tttgaatacc gtttaaggaa gaggttgtga
     3841 aatcagcgtt ttgacctgag tattagctta acaaacggaa aaatagttcc tcatattttg
     3901 ccgtttgtta agctaatacc gagggtcagc tgattgaaca ccatttaaga aagaggtcgt
     3961 gagcctgccg tttcactctg tgtcataaaa aagccaatct actttgatag aaaaagcacg
     4021 taggactaaa acagttctgc gtgctttttt tattgtgtgt taaatatcgt aaatgaagat
     4081 agatattttt atgattcgac gatagagacg ttgaaatctt tcaacagctc taaagcggat
     4141 tctccgtgtt ttctactgga gactaacatt ggatcaacaa aaaagtctgc ttcaggaaaa
     4201 gcactctgca ggcctatcag attagagagt acacacaagt ttgtttcaat cccgactact
     4261 tcgatctctt tttgttcttc tttgctttca aataaagttt cctggatttc agctaaagtt
     4321 tcaggtggaa tcgtaaagta atacttttta atcactcgtt cattttcttg tggagaaaga
     4381 agagggatca attgcaaatc ttctcgttct tcttctttgt ccttcagttc aactggtata
     4441 tcccgtgtga agagaatata ttcattattt tggcgtgctt tagctaatct ttgagcaata
     4501 cgttctgcca attgatctga ctctggaata taaaattcgc tgtttggatc aagaatatga
     4561 ttttgcatat caataataac taacattttc tttcctccta cattcatatc gtcattttat
     4621 tctttttaat agaagttttt taaaatataa gcaacaccag cttcttcatt cgtcagtgtt
     4681 acttggtttg caatttcttt tacttgtcgc tgtgcattcc ccatcgcaat actcaacccg
     4741 ctgtaattca acatatcaat gtcgttttct tgatcgccaa aagccatgat gtcactcgat
     4801 tcgattccaa ggtaatccgc cagaaaaaca agtgaatgag ctttagtgat acctgtaggc
     4861 gtgatttcta agaaatgcgg atcagagaat actgattgga taccatctgc ttgcagatct
     4921 ctttgtagct tctgtagttt ttcttcactc ttatctgtta atgctaattt aagatagcta
     4981 agagaaggat cttccaacat atttaaaatt tgatcaaaag aatggttctg taaattgaaa
     5041 tgttcataat aagggtcatc tttgactaga tttgattcat cgaatgtcag ctgatcatct
     5101 tgggtttctc ggctagcaat gatggatatt ttcgcttctt gagcatagaa gaaggctttt
     5161 ctcagtgtat cgctatctat ttttgaacgt ctgagaactt tcgccatttt tccatccttc
     5221 atttcagcaa tcagtgaacc attggaagaa atcaaatagc caccgattcc taattcggaa
     5281 aaaatatctt tagcagaaat gctgttcctt ccggtagcga cggttacgat tccgccattt
     5341 tcatcaaatt tccgaagtgc ttggatattt tcttctggta tctttccatt tcgatcaagc
     5401 aaggtaccgt ctaaatcaat cgctgctagt ttcattttat cttcctactt tctttttaca
     5461 tatctatttt cctgttacct taagattaaa tgagaattta aaaaaatgaa actaacttgc
     5521 tttgtcatta tgaatttttt caaaaaacat tcttaagaaa aaggtggcta tatatagtag
     5581 tttttggtca atacctttga ataaaaagcc atgaaaaacg aatagttagc gcttaccgat
     5641 gcgttttgtg ataaaaaaat tttaaaatat tcaatgaaaa caaagcatat attttgcttt
     5701 aaaaccaaat gaggaatatt ctagatgtag aacaggttag aaaaagatta gaaaaaggag
     5761 tgattttgat ggagaagaga tacggcgtag ttcctgtggt aactgcttca gacgaaaatt
     5821 atgctcctta cttgagcgtg atgatcgcaa ctgcattaga aaattgcaat aaaacaagac
     5881 gcataaaatt ttatgtgatt gacgatggtc tatcagaata tagtaaagaa ggattggaag
     5941 aaacggtaaa taaatattca agtaatgcaa gtatccaatt cctgacagtg gaaaaagata
     6001 tctacgaaga cttcctagtc agtgaccata tcacaactac cgcttactta agaatttctt
     6061 taccaaactt attagctaaa gaggattata agaaagtcct ttacttagat tcagatgtgt
     6121 tagtactaga cgatatcgta aaactatatg atgagccgtt aaatggaaaa acaatcggcg
     6181 ctattatcga tccaggccaa gtgaaagctt tggaaagatt aggaatcgat tccgatgact
     6241 tgtacttcaa ttcaggagtg atggtgattg acattgatca atggaataaa aaagaaatta
     6301 cagaaaaaac tatccattac ctcagtgaaa atggcgatcg aatcatctat cacgaccaag
     6361 atgctttgaa tgctgtactt tatgaagatt gggaacaact tcatccaaaa tggaacatgc
     6421 agacttcgct gatttttgaa cgtcatccag caccaaatga aaaatatgaa cgtcagtata
     6481 aagaaggaaa tgaaaaacct tcgatcgttc actttacagg acatgataaa ccttggaata
     6541 cgttgaaaga tcatccgtat accaatttat acttaaaaaa attagcacac agtactctaa
     6601 cgaaagtagg cgagatcaat gaataaaaaa gaaatagcag tagtcgcaag ttgtaacaca
     6661 aaattcgtac cacatttagc tgcattattt gtctcagtat tagataattg caacccgtct
     6721 aaatttgttc ggttctatgt gattgacgat gatatcgatt ttgaaagtaa acagctttta
     6781 cgcttctcag tgaaaaacgc acgaatgaac tcagatgtgg aattcttgaa aatcaataaa
     6841 gaattcttta caaatgtggt aatcagcgat cgtattccag aaacagctta ttatcgtatt
     6901 gcgattccgg aattgttccg cggcacagaa gttgaacgta tcttatatat ggattgcgac
     6961 atgatcgctt tacaagatat ctctaaatta tggcgtcttg acttcggtga ttcaatcgta
     7021 gcagctgttg aagacgctgg gttccatcaa cgactggaaa aaatgaaaat ttcagctaaa
     7081 tcaatgcgtt atttcaactc aggtttgatg ctgatcaatg tgaaaaaatg gttagatgaa
     7141 aatattacgc aaaaagtatt agatttcatc gaacataatc cagaaaaatt acgattccat
     7201 gaccaagatg cattaaatgc tatcttacat gaccgttggt taccacttca tccgcgttgg
     7261 aatgcacaag gctatatcat ggcaaaagca aaaaaacatc caacagcagc aggtgaacgt
     7321 gaatacgaag aaactcgcaa caatccttac attatccatt tttcaggaca tgtgaaaccg
     7381 tggagcaagg attttgaagg gccaacgaag aaatattacg aaaaatatgc agggatgacg
     7441 gctttccgtt gtgtagctaa attccctaaa tatccaaaat atgcaaaagt tcaaccaaaa
     7501 acagatgtag ttgttaaata atagaagaca acaactgaag agggggagta ggaatggaaa
     7561 ttacaatgtc taaaaatgca gtagagacgt taattgaaaa ggttggggaa aatacaaaaa
     7621 tcgcactcgc gcttatcaat gattccgatc catttctaag ggacaaaggt gcttttgcaa
     7681 aaggcagctt ttttcaaatc attccttttg tttcggaatt tggagaatat gcgactaaaa
     7741 tcgagcatcc attattggac atctatacat ctaaattaga gcaaaattat ttcggtaaac
     7801 gattgaacat ggacttcaac aaacagcttg acagcttttc attagaaaat gaaatcgcag
     7861 tactcgatta taatatcaaa ttaaagaact gcttcttcag ctaatagttt cgagaaagtc
     7921 caaaaaggag gtatacattg agatactact ttgtggatga agaaaagaat gtaatagaaa
     7981 cagatgaaaa aaaatataat tggctcgtac ttgatagtgc aaagcccgaa gagattgagc
     8041 aagcaatcga agaattcgag cttcctgatg atattttcgt aggaaccgaa tatccggaag
     8101 aagtttctcg gatggagcgc ctttatgaga cgaaactaga gcatccattt tctttggtag
     8161 tgattaatct agatcagtca gataatcgta tcgaaaaaaa attaacgcca atatcttttg
     8221 tactttccga taatctcttg attacttgta tcgatagaaa aaccgaattt gtggatcggc
     8281 tgctgacaaa gcatggaaat catttaaact cgtttgaaaa gatcatcacg tatacattat
     8341 tagatattta cacccattac gtgaaagaac taagagagat gaaaaagcga attgacgctt
     8401 tggataaagc agctcgtaaa acaacggaaa atgaagaact gtataaacag gcagatcttg
     8461 aaagagacat cgtatatatc gatcatacct taagagatca acgggaaaca atggatcaat
     8521 gatcaattat ggaattctga aactttcatc aaacgtttag acgatgaaca gctactctat
     8581 gatgtccatt tgagacagcg acaaacagaa aaaatgatcg agatctatcg agatttatta
     8641 gagagtattg gtgatctatt caacgggatg atggacaata atctaaatca tatcatgaaa
     8701 tatctagatt cagctgcatt aatcatttcc gttccggcgt tgttcgcagg gatttgggga
     8761 atgaatacag gaggattacc gggtaaaagt tctgctctag gctttatact cgtagtcttt
     8821 ggctctttga tagcagcagt agttttaggt taccatttat accggaaaga ttatacaaat
     8881 taaagaatct atttaaaaca ggtatcaaac aaagaaattt gttttggcaa tacaatttaa
     8941 aaactaggag gaatacagca atgacagaac caaaattaat cgacccgcga aacttgtacc
     9001 atacggagaa atttcctaaa caagatcagg atacaccagc tttacagcag aatatgattc
     9061 ctgttcctga ttgtggagaa gaatcctatg aaggcaataa tcaactagaa aaccgccgtg
     9121 tactaatcac tggtggagat tcagggatcg gtcgtgcagc agcgattgca tttgctagag
     9181 aaggggcaga tatcgctctt caattcttcc caggagaaga aaaagatgca gaggaagtag
     9241 caaaatacgt gaaagttgca ggacgtaaga ttgtcttact accttttgat cttcgtgacg
     9301 aacaagcacc taaagaaatc atagataaag ccgtgagtga acttggcggg ctagatacga
     9361 tggtactaaa cgcaggacag caaatttctt gtcagtctat tgctgagtta ccacttgagc
     9421 aagtcaaaga cacatttatg ataaacatca tcgctatgtt tgctttagtg aaagaagctg
     9481 ttccgcatat cccagcagga ggagcaatcg taacaacaac ttctgttcaa gcattcaatc
     9541 caagcgaaca tttattagat tacgcagcaa caaaagcttc aatcgctaac tttacgatcg
     9601 gtttagcaaa acagcttgca cctaaaggaa tccgtgtaaa tggtgtagca cctggtccaa
     9661 tctggacacc attacaacta gacgaaggac aaccttctga ttcgatccct gaatttggtc
     9721 agcaaagttt actagaacgt gcaggtcagc caggagaatt agcaccagtt tatgttttct
     9781 tagcatcgaa taaagcaagt tatgttacag cccaaattta cggagtaact ggtggagaag
     9841 cgatcaactt ataagaagtt gatcgtttca cccctatgag gaggtgcgaa aatgaataaa
     9901 ggtgtaaaaa cgatcggagt gatcggaaca ttacttttgc tatctgtgct tttgtttgcg
     9961 atactattaa gtgcaaccta tccattgcct tttcagctag agaagtttcg attcttttcc
    10021 atcactaatt catacgtgca acaatatgta ttttggcttg ccgttgcatt tgctattttg
    10081 acaattatca cgttacttgt tttcctgttt tatccaaaaa caatcggaaa ctttctactg
    10141 aaacatggtg atggggagtt gacgttggat aaaaaagcaa ttgaaggaat ggttcgttct
    10201 cacttgcatg aagatgaatt catccattca ccaaaagtaa atgtcaaagc aacgaaaaac
    10261 aagatcgccg tcaatgtaaa aggggagttg aaacgaactt cagcactcat tggtaaaaca
    10321 ggaacattga tgaaagaaat cgaaaatgaa gtacaacaca tattgggaac aaaagagcca
    10381 gtgaaagtat cggtgaaata cacaggcttt gaagaaccag ctaaacgaag caatgaccgc
    10441 aaacgagtag aatagggggg gaccaaaaat gaaagaacta ttttcgacat acaagctccc
    10501 tatcatcttt ggggtacttg gattgatatt agccgtttta tggatcaccg tgggcttttt
    10561 caagacctta ttgatcttga tcatggcagc gatcggcgtc gctatcggtt tttatctgaa
    10621 acaaacgaaa atcttagatc actattttaa atcttaggag gaaacatcca tgaataacaa
    10681 taacaaaaat aataacaata aaatgaacaa ccaaaaacca gtgtctgcac atccagaccc
    10741 aacgacacca aaccaatcaa atggtgtgaa cgatgaaaag aacaaaacag caccagtatc
    10801 tgcacatcca gatccagtag tccctaacgt tcaacaagga gtagaagaga agaaacatga
    10861 tgcagaaaag catgcacctc atcatccagg aactccagaa tctaaagttc cagaacaaca
    10921 tgatgcaatc gatccttcta aacctgtgga agagcaaaaa catccttctg accatgcgaa
    10981 agcacaagaa aaacttagtt ctgaccacac aaacggacaa ggaaaacttg gttctgatca
    11041 tacaaataac caaggaaagc atgattctga acaggaagat tcaatgcgcg gtgagctgaa
    11101 ttatgaagat aaagttgtgc aaaaaatcat cggaatcgca attgaacaag tagacggttt
    11161 attatctgca aacggtggtt tcttctctaa tgtggcagga aaacttgtga atacagataa
    11221 tgtaacggct gggatcgaaa cagaagtcgg taaaaaacaa gtagcagttg atatggatgt
    11281 cattgtggaa tatggcaaag atatcgaaaa aatctttgaa gaaatgcaag aagtaatcgg
    11341 caaagaagta aaaaatatga cacatttaga agtgatcgaa gtcaacgcta acgtagtgga
    11401 catcaaaaca aaagaagaat ttgaaaaaga tcaagaaacg gtgcaagaca aagtaactga
    11461 cgcagcgaaa aaaaccggtg aatttgcttc gaatcaaaca gataaagtaa aatcagcagc
    11521 tggaagcggc gcacaaaaag taaaagaaaa tacagaacca cgggttcagt aataaggaag
    11581 taaaacatta ggaggaacga aacatgggat ttatttggtc acttatcgtc ggaggaatta
    11641 tcggagcaat tgcaggagca atcacgaata aaggttcttc gatggggatt attgcaaatg
    11701 tcgtagcagg tttagttgga tcagcacttg gtcaagcatt attaggttct tggggaccaa
    11761 gtattgcagg aatggcaatc gtgccatcat tgattggtgc catcatttta gtactaatcg
    11821 tatcattctt tgctcgaaaa ctgtaaaaag acttttaaaa agaggtcgtg aaaaagctgt
    11881 tcttcatcaa gtaataagaa cagccaaaca aaaatagctt ctcatatttt tcatttggtt
    11941 gggcatatta tcgaagatgc aagcttttga acactgttta tacggaataa gaggctgtga
    12001 caagactttt gtcacagcct cttatttatg cgggcaaatt cccaattaga tttttaaaag
    12061 tttttcctta aatgtgtctt tattgataca gagaagcttc tttaataaaa caatgcctcc
    12121 ctaaattttc ttgagatagg aaaggtgaac atacaaaata atacgaccac tttgaaaacc
    12181 cagatgatcc acaaatggat cgtatgatac tgatgaagta aaaagcaatg gatcagaaac
    12241 tcaaagagat tgaaaaagac aaggaagaaa taatatctct tttttactct tgtctgtttt
    12301 agccaataat agctcgtaaa gtaatctaga caaacaaata gaagtaaaca aagtttcgta
    12361 agagcagcaa tcgtatcatg ttgctctgct agacgattga cgagcaggaa aaatgttggt
    12421 aatggaatat agatcacgag taatgaaaga aaaaagtaaa caataaatgg catactattc
    12481 ctcctaattg tgtgagttcg ccctcatttt aaaataacga tatttgtttg tgaagctttt
    12541 tcgtgtcgta acaaatgtta tctaatgtat ttttaaataa ataatcatta ttatcaaaat
    12601 aatg
//
LOCUS       DAFEEZ010000079        12246 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000079
VERSION     DAFEEZ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.082"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="LP245_002459"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="LP245_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBL1520338.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="LP245_002460"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="LP245_002460"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBL1520339.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="LP245_002461"
     CDS             complement(2169..2906)
                     /locus_tag="LP245_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBL1520340.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="LP245_002462"
     CDS             complement(2997..3524)
                     /locus_tag="LP245_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520341.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="LP245_002463"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="LP245_002463"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBL1520342.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="LP245_002464"
     CDS             complement(4401..4886)
                     /locus_tag="LP245_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBL1520343.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="LP245_002465"
     CDS             complement(5039..5236)
                     /locus_tag="LP245_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520344.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="LP245_002466"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="LP245_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBL1520345.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="LP245_002467"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="LP245_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBL1520346.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="LP245_002468"
     CDS             9211..9423
                     /locus_tag="LP245_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBL1520347.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="LP245_002469"
     CDS             9425..11104
                     /locus_tag="LP245_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBL1520348.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(11358..11558)
                     /locus_tag="LP245_002470"
     CDS             complement(11358..11558)
                     /locus_tag="LP245_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1520349.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(11708..11869)
                     /locus_tag="LP245_002471"
                     /pseudo
     CDS             complement(11708..11869)
                     /locus_tag="LP245_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
BASE COUNT         3575 a         2636 c         2117 g         3918 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaatacctgc cacaagagaa attgtctctt
    11281 gtggcaggta tttttgttac tcgctttgtt ctctcgtaaa aattgatgtc taccatcaat
    11341 ttgatttaca gataaaatta agcttttaca acgtttgcag cttgtgggcc gcggtctgat
    11401 tcttcaacgt cgaaagtcac tgcttgacct tcttctaatg ttttgaatcc gtcaccttgg
    11461 atagctgaga agtgaacgaa tacgtcgctt ccatcttcac gtgagataaa tccaaatcct
    11521 ttttcagcgt tgaaccattt tactgttccg ttttccataa taatatcctc ctcgtgccaa
    11581 aagcactaat ttaaattgta acattgctcg tgtacgatag aggtgcaaca gatgtttcaa
    11641 cttctattcc caaacaaaat tacaatataa ttgtacactt gcttcatttt ttttgcaaga
    11701 aagcaactta cttctcttcc atcattcctt cttctctcaa actaaaatat cgtttgcgtc
    11761 cgatgatcaa gtggtccagt acagtgatcc ccatcatttc tccacacttt tgtatccttt
    11821 tggtaaaatt catatcctgc tgcgatggaa taacattacc agaaggataa tataggttag
    11881 tacacgtata aaaatatctt ttatattgac acaatttatt taacaagtat aataataatt
    11941 gaaagtgaat ttaaacaaat atacaccata aacacaacgt acctgcgaat acgttgtgtt
    12001 tttttctttt tcaaaaaaag acgcttaccg ctgcgaaaca gtaagcgcca ttgtcggctc
    12061 taatgtttat ctagccaatg actaaataat gccaaagtta aaccaattaa caatggcaag
    12121 agcacgtgct ccaaagtgaa ttcaaacaaa tcatacacct cctcccacga aaatctctgt
    12181 ggaagcgacg agccgacatt ttattatacc attattgaat tttatttttt atcaaataga
    12241 ttaaat
//
LOCUS       DAFEEZ010000080        11629 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.083, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000080
VERSION     DAFEEZ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11629
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.083"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(133..2208)
                     /locus_tag="LP245_002472"
     CDS             complement(133..2208)
                     /locus_tag="LP245_002472"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBL1520350.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKESKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDYEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTYHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDADRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2210..3127)
                     /gene="glyQ"
                     /locus_tag="LP245_002473"
     CDS             complement(2210..3127)
                     /gene="glyQ"
                     /locus_tag="LP245_002473"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBL1520351.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPETVKEAE"
     gene            complement(3513..4325)
                     /gene="recO"
                     /locus_tag="LP245_002474"
     CDS             complement(3513..4325)
                     /gene="recO"
                     /locus_tag="LP245_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBL1520352.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKDMSEKDLPKKEE"
     gene            complement(4468..5367)
                     /gene="era"
                     /locus_tag="LP245_002475"
     CDS             complement(4468..5367)
                     /gene="era"
                     /locus_tag="LP245_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBL1520353.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5382..5777)
                     /locus_tag="LP245_002476"
     CDS             complement(5382..5777)
                     /locus_tag="LP245_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBL1520354.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIVGLILFVPKIYHLLFN"
     gene            complement(5761..6237)
                     /gene="ybeY"
                     /locus_tag="LP245_002477"
     CDS             complement(5761..6237)
                     /gene="ybeY"
                     /locus_tag="LP245_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBL1520355.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6266..8458)
                     /locus_tag="LP245_002478"
     CDS             complement(6266..8458)
                     /locus_tag="LP245_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBL1520356.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLFAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(8482..9453)
                     /locus_tag="LP245_002479"
     CDS             complement(8482..9453)
                     /locus_tag="LP245_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBL1520357.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10159..11538
                     /gene="brnQ"
                     /locus_tag="LP245_002480"
     CDS             10159..11538
                     /gene="brnQ"
                     /locus_tag="LP245_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBL1520358.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGTNWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
BASE COUNT         3149 a         2475 c         2126 g         3879 t
ORIGIN      
        1 tttttaaaag ttacacaaaa aataaaataa caaaaaaaat taacattgaa ttaataatag
       61 ttatttataa caaataaacc agagaaatag cctattttgt gcctgttctc tggtttattt
      121 acatattaga aattattttg tgatgatttg atctaaactt gctagtgaca aagccatggc
      181 agcaatttga cttaattgcg ttaatcggtt cttacgtact gctggttctt ctgccatgac
      241 catcgtctga tcaaaataat tttcgatcag tgggcgaagg cttacaagct gatcataatt
      301 ttcgttgatc gtttggtcag caaagcttgt tttcattgcc tctactgctt tgtgcagttc
      361 tttctccgct tcgttttcga acagttcagg gtctacttct gattgttttt caagctccgc
      421 ttttttcgct aagttcacga cacgtgtcaa agcttccatc gatggtttga agtcttcatc
      481 tgcaagatgc tgcttgaaca attgtgctgc tgcaaatact tttgtcagat ctttttgttc
      541 tgcattcaaa acagcttcga tgacatcatg acgaatattc ttcgttgtca ataattggcg
      601 cagacggcct ttgataaagt cgatcacctg ttgttgtccc gctgacaagc caatgccaaa
      661 acgatccgca tctttactga taacttcact aatcgtttct tgcagaacag ataaaggaaa
      721 ggcccatttt ttcgattcga tgattcgaac gacaccatat gcttgacggc gcaaagcata
      781 tggatcgttt gagccacttg ggatcatccc aactgcaaag aaagaaaaga tactatctaa
      841 tttatcagca atcgctaaaa cagaacctac tgtagtctca ggtagatctc cttcactgga
      901 tataggcatg taatgttcac ggattgctgt tgctacggct ggtttctcgc ctttaagcag
      961 agcatatttt tctcccatga tcccttgtag ttcagggaat tctcctacca tgttggttac
     1021 tagatcaaat ttatagattt cagcagcgcg ttgcagatcc atcaattctt cctcagatag
     1081 tcctacttgc tcgcctatga tgcgggcgat gacttgtacc cgttgcattt tctcgtagat
     1141 gctaccgatt ttttcatggt aagtaacagt ttttaatttt tcaacgtatt ggtcgattga
     1201 agctttcttg tcttcattat aaaagaattc cgcatcttct aaacgagcag tcaatacttt
     1261 ttgattgcct cgaaccacat tttccaattt tacccgatca ccattacgag cagaaataaa
     1321 atgaggaagc agcatacctt gatcattccg tacctcgaaa taacgttgat gttctttcat
     1381 agaagtgact agtacttctt caggaacaga aagatatttt tcttcgtagt cgccagaaaa
     1441 gacagttgga tattcgacta aattgttgac ttcttctagt aaatcttcgt ctagatcaat
     1501 aacccagtga tttttttctg ctaattcgtt tgcttgtgta acgatcattt cttgtctttt
     1561 ttgcggagac gcaatgacga attgttcatt caatttttct tcatattctt ttgcatgcgc
     1621 aaatgtcaca tcttcgccta agaaacgatg acctcgagag gctctgcctg ttttgacatc
     1681 caagatttcg aatgggatta cttcatcatc taacaatgcc acgatccagt gaatagggcg
     1741 gatatattca aaatcgtatt ctgcccaatg catcgttaca gggaaagtca ggcttttaat
     1801 gacatctgct aaacctgtca atacttcttt ggattcctta ccatgagtgt atttcgttac
     1861 atagacatat tccacacctt ttaattctct aaaagtgata gcgtctgtcg tcagaccttg
     1921 tccgcggaca aatccttccg ctgctttcgt ccagtttcca tctgcgtcca aagcaatttt
     1981 tttggctggt cctttgactt cttcttcact gtccgcttgt cgttctggaa tatttgttac
     2041 tttgattgct aaacggcgcg gtgtggaaaa tgtttcgatc gtatcataag tcaattggtt
     2101 ttcatctaaa aattttgctg ttttttcttc taattgtttc atgcttggtg tgacaacatg
     2161 ggcaggcatt tcttccagcc cgatttcaag taataagtct tttgccatct tattcagcct
     2221 ccttcacggt ttctggattt gctgtgtttt tattcaacaa agggaatcct aatttttcgc
     2281 gttctgccac aaagattttg gctacagcac gagccatgtt gcggatacgg gaaagataac
     2341 cggcacgctc tgttacggat actgcaccgc gagcatctaa taaattgaat gtatggctgc
     2401 atttcaaaat ataatcatac gctggatgaa caagattttc atcgatacag cgtttagctt
     2461 ctttttcaaa acgatcaaag ttgcttagta gcaagtcttg atcgcttact tcaaaagaat
     2521 atttggaatg ttcatattct ggttgtttga agatctcgcc atatttcacg ccatcagccc
     2581 attctaaatc atagacactt tcaacttctt ggatataaga agcaagacgt tctagtccat
     2641 aagtgatctc agaagtgact ggtttacaag gcagtccacc aacttgctgg aagtacgtga
     2701 attgtgtgat ttccattccg tcaagccata cttcccaacc cacaccggca cagcccatgg
     2761 atgggttctc ccagttgtct tcaacaaaac ggatgtcgtg ttctaatgga tcgattccta
     2821 aaaggcgcaa gctttctaaa taaagctctt ggatattctc aggtgaaggt ttcatcacga
     2881 cttggaattg atgatgctga tacaaacggt ttgggttttc accataacgt ccatcagctg
     2941 gtcggcgaga tggttctacg taagcagcat tccatggttc tggtccgatt gcccgtaaaa
     3001 aggtatatgg gctcatcgta cctgctcctt tttctgtgtc atacgcttgc atcagcatgc
     3061 agccgtttga tgaccaaaat ttttgtaatg ttaaaatcat atcttggacg gtcaattttt
     3121 tactcatctg ttttgcccct ttcaatttta aagcgttgct gtcaaataag aatacaggaa
     3181 agaaaacgac aaaaaatccc tatgtctgat tacagacata gggacgaata attcgcggtt
     3241 ccaccctact tccgaataaa gattcggcag cttcatttat cgtactcgca agtgcctctt
     3301 caaaaatcgt ttgggtccgg ctcccactct cccgaactcg ctaaaccacg tgttttttac
     3361 tgatcttggt caatgtacgt attcattttg cagttttctt gtttctataa tagatcctct
     3421 cactgaacga tctatttgat ctacggttaa taatagacgg aactccctgt gtttgtcaaa
     3481 tggttttgat tttttgttgt atgtttcatt tactattctt cttttttagg tagatctttt
     3541 tcagacatgt ctttctctgg cgtctttaat acgtgtgccc aagacttcat ttgatcgatg
     3601 aactttttgc ttttcaaatg aataccgaca tattcatcat acagctggtc gatgagttca
     3661 cggattgctt gtttggtttc ttctttcaga tggattccac tgattttatc ataagaaata
     3721 gctgaaaaca tccgaacgaa ataaacagct cgaggatctg catgataacg gtgatcgtcc
     3781 atcgaccaat gtctttcgca tatcacacca ccatatttgg aagaatagtc aaattttcct
     3841 tttgtttccc cacatacgac gcagtgtgtc cagattggtg caattccgaa gcgttgcagt
     3901 atttgaactt caaagatatt cgtgatgatt tctgcatcat ctccttgatc catccgctgc
     3961 agagcttgtt gcgtaaattg gaataaatgc gggtcatatt gatgatcttc gattgctgca
     4021 tctactagat ttagcaaata ggtaccataa ccgctcaaaa agatatcttc ttggatgttc
     4081 cgaaacgcat ggacgtcttt gacactgctt aaaaacgaca aaccttcact tcgaaaatta
     4141 ccgatataga ctgcttcggt aaaggggagc aaagccggag ctaatggctg attttgccga
     4201 tggattcctt tgatataaaa catcattttg ccagaagatt ccgtaaagat tttgactaat
     4261 ttatcttttt ctttgtaatt acggctagat aaaatcaagc ctttcgattc tgcaagctgg
     4321 ctcatattct ccctcctaaa aaataaatct ggaaaagcag attctgccga tccagattat
     4381 ttatgtttcg atcttccgcc gtttttctca acgtgcggat ttttatccag tttatttcta
     4441 tacttaacct ataagaagtt cagaatatca gtattcatct tttcggtagc cgaagtcttg
     4501 cagatagact tttttgtctc gccagtcttt ttggactttg acccaaagtt ctagaaatac
     4561 tttgtctcct aaaagatttt cgatatcctt tcttgctttc gttcctactt gcttcagcat
     4621 ttttccgcct ttgccgataa tgattccttt ttggctatct ctttcgacga tgatcgtggc
     4681 ctggatatgg attttatcat tctcgtttcg cttcatcgaa tcaacaacga ctgcgacaga
     4741 atgaggcact tcgtctcgtg ttaaaaacaa gactttctca cggatcaatt cagaaacgat
     4801 gaagtattca ggatgatcag tcacttgatc atctggaaaa tattgtgggc cctctggcat
     4861 ttcactgact aatacatcca tcaaacgttc gacgttgttt ccttctgtag cagaaattgg
     4921 aatcacttgt gcaaagggca tctgcgttga ataatcttcg atgattccca acaactcgtc
     4981 tggatggatt ttatcgattt tattgataat cagataaaca ggagaatgca cgttttttag
     5041 acgttcaata ataaaatcgt ctccccggcc gcgtttttga tcagcgctga tcataaataa
     5101 gaccgcgtcc acttctttca acgcactgta agctgcttct accataaaat ctcctaaacg
     5161 atgctttggt ttatggattc ctggtgtgtc aataaaaatc aactgagctt ctggtgtagt
     5221 atatactcct tggattttat ttctagttgt ctgcgcctta tcactcatga tggcaatttt
     5281 ttgacccacg attcgattca ataatgtgga ttttcctaca ttcgggcggc cgacgattgc
     5341 gacaaaccct gatttatgtt ctggcatata cgttctcctt tttaattaaa caacaaatga
     5401 tatattttag ggacaaataa aatcaaccca acgatgacgg caaaacaagc ggtcactaaa
     5461 actgctccag ctgccatatc tttgattttt ttcccaatcg gatgaaaatg aaaatccgta
     5521 aacatgtcta cgacattttc aaaaacagta ttgatgatct ctactatcca tacgagaaaa
     5581 acagctaaaa gcagccataa ccattctatc cgatcaagtt ggaaaatcac gcccataaac
     5641 aaagcgagga ttccgaacgc aacatgtttc ctcatgttgc gttcttcctc aaaaacagtt
     5701 ttgactcctt ggacggcaaa ttccacggac atcaggaaat gtttgttttt ctctacgttt
     5761 ttatctttta agtccatagg catctaagat ctctttctgt aaaccaaaca tttctttctc
     5821 atcctctggt gtcatatggt catacccgtt gatatgcaag aatccatgaa ccgctaaaaa
     5881 gccaagttcc cgatcatacg aatggccgta agcttctgct tgctctgcag cacgttcagt
     5941 agagatcatg atgtctccca gtacacgagg caatggattc tctccatctt caaaaatcac
     6001 tgggatttcg tcttcaccct cttcttccaa ggcaaaactg atgacgtctg tcggtgcatc
     6061 ttttccacgg taatcacgat tgattacttg gatcgctgcg ttgtccatga aagtaacaga
     6121 catttctgtt tcttctggca actctaaata tgatgctgca aattgcaaca agtcgtcgat
     6181 ttctttcatt ttctcttctg agacttggtt tgtttcatcc atgaaggtaa tatccattat
     6241 acatcgcttc tttctattct tcttgctatt cttcttgttc ttcttttatc ttctcaactt
     6301 ccgatttcat tttaggatat ttgatccgag aatggaaggt actgcttaaa ccgctgatca
     6361 atgatttttc tactttacgg atttctttta acgtcaatcc actgtcatcc aattgtccat
     6421 cggaaatacg ctcttctata agattatgga caaaactttc gattttttcg cttgttggat
     6481 ggtccattgc ccgtactgcc gcttcacaac tgtcagctat attgacgatt cctgcttcac
     6541 ggctttgagg ttttggtcca ggataacgga attgctcttc cgtgacttcc gggttgcgtt
     6601 cctttgcctt aacgtagaaa taacgcatca gcgtggttcc atgatgctgt ctgcaaatat
     6661 cgatcaccat ttgcggcata ttataatctt ccaatatttt ggcaccatct gtcacatgtc
     6721 caaagataat atgtttactg tcttctggca ataagaaatt gtgcggattt tccgctcctg
     6781 aaggcaagtt ctcaacgaaa aagctggcgt gtttgatctt gccgatatca tgataatagc
     6841 aagctactcg agttagtaaa gaacgtccac cgatttctgc tacagcatta gcacttagat
     6901 tggctaccat catgctatga tgatacgtac ctggtgcttc ttctaacaac tgtttcaata
     6961 aagggtgatt aggattgctg agttcattta atacgatcac actatcatca ttgaccatca
     7021 attcaatata ggggtgcaga cctatcgtca gcaagaatga gaacaatgca cctgtgaatc
     7081 cgcagactag cgttaaccaa gtcgttgcat ccccaaagct cattccttgg tagataatca
     7141 aaatgacatc catcatcaca gggaaaataa tgacccacat agcagcgaat aacccttgtt
     7201 ctgagatccg tttgcgtctg acgatcgttg ccatgagacc agaaaataca taggacatca
     7261 aaataactgt cagaaagttc gtgccaatcg aatcataaaa aatgaaaagt gcggatactg
     7321 cttggaaaat accagccatg atccctgctc ttcgattcaa gaaaaagctt aaaacaagtg
     7381 gagcaaaagc cgcggggtaa aacagcggaa tataagcagc ttgttctgtt tggaagagtt
     7441 ggaaaaattt cattagtact acgctgactg acattgctgt cacgtagaaa agtacgtatt
     7501 ttgttctttc tcctgcattt tgaaattgaa gtgaattata aatcagtaca ccgatttgaa
     7561 gcaaaacagc taaaaccatg gcaatgagtg ggaaaatcga agtcgtttga ttcgtcaatc
     7621 ctagtaattc caattttttc atcgctgaag catcaatttg atttccttcg cgaacaatga
     7681 tttctccttg gaagatcatc actggttgta cagcttctcg tgcagattgt tttaattctt
     7741 ctgtcttttt ctcattcaat acatcattga ctacaatgcc ttgatccact aagtagcgga
     7801 tcatttgttg ctgctctgtt gtgacattca aatactgaat ctgatcttct gcttcttgtt
     7861 taaaagcttc caattcgctt tcacgaactt gtttactcat ctgttcgtca atgagcttca
     7921 aactttcatc cctaaccgtg tgaatttccg tttcagtcat ttcaaatatc gtcgaataaa
     7981 aattgttcgg cagtttttgg taaaacgcaa cgttttctgc attcacgttt tcaaaatttt
     8041 tcttcagtgt agcaatccgc tcttctgtag taggtttcgg gatattttca tcttccttcg
     8101 ccttatctac cttgtcatta taagatttgt tgatggtatc attcgtctta tcgatcaatt
     8161 cgaataattg cttgatccga ttgttctggt catctgccag atctttttga taagtatatt
     8221 ctggagtcac tgcttctgct gctagttttc ttctttgttc ggtttcttcc gtgttctcga
     8281 tcgttttatt cgcacggata ctctcttctg ctacttggcc ttctctaaaa tcattggcct
     8341 tttgtttgac actactaaat gtaacgccgc aaacaatgat aaaaaacaag aacagaagga
     8401 aaggcaatgc tgcctttccg agtttttctt gtagtttctg cagtgtttta ttcaacatgt
     8461 gcttatcctc ctaagcaaag cttattcttg atgaagatcc gccttttcat aagctttgat
     8521 gatttcggca actacagggt gccgaacaac gtcacttgct tcaaaattaa caaaatcgat
     8581 ttttttgatt tgctttagtg ttcgttctgc atgaacaaga ccacttgtcg tccctcgagg
     8641 caagtctatc tgacttgtat ccccattgac aatcattttt gattgataac cgagacgggt
     8701 caagaacatt ttcatctgag cgactgtcgt gttttgtgct tcgtccaaga taacgaatgc
     8761 atcatccaat gtccgccccc gcatgtaagc taatggtgcg atttcgatta cgcctcgttc
     8821 catcaatcgg ttcgtatgat ccaatccaaa aatttggtat aaagcatcat aaacaggccg
     8881 cagataagga tccacttttt ctttcagatc ccctggtaga aagcctaggt tttcccctgc
     8941 ctctacagcg ggccgcgtca aaatgatttt ttgcacttcg ccttttttta aggcagcaat
     9001 tgctaatact acggcaagaa acgttttccc tgttccggct ggccctacac caaatacgat
     9061 gtcatgtttg gctaccgatt caacatattt cttttgaccg ctgtttttta cccgtatagg
     9121 ttttccatta cggtctttga cgatctcttc ctcatacatc tcaacaaaat aatctaatgt
     9181 acctttttgc cccattttca atgccgtcac aacatcgggc gtacttacgt ggattcctcg
     9241 tttgatcaat tcctgtaatg tccgaatgac tgaggcagcc aaggaaatct gggattgttc
     9301 accaatgatc tgaatgattt ctccacgtgt atggatggtt gtttccgttg tttcctcgat
     9361 cagttttata tgcttgtcgt gtgcacctaa aagcatgctg acatcatcag cagctgtcaa
     9421 tctaatctct aaagaactag actcttccgt caaaaataga catccccttt ttttcgattc
     9481 attctttcct attttaccat actcagaaga aactatatag caaataagaa aaggttgtaa
     9541 aagagtcgtt taaccatacg taccaagaaa cgttaaaaaa tagccgtttc cattcgctaa
     9601 aggtctcgtt ttgataaaaa gaatctgaga atgtaagtta tatgaaagtg gagaacaaaa
     9661 tattccgttt cattcagcag gtattctcta ggtatttttc ttgtttcaaa aaaagaaaac
     9721 aaaatagtta aaatattctt gcatttcaaa aaaaacaggt gtattattac gtcaacaaat
     9781 aaacatacag caaagcgtcg aggaaaacag taggctattc aacgatttat tcccagtgag
     9841 tcatgtaagt gagaaatgac aataaatcga atagacgaac atcatttccg agtcaatgtc
     9901 gaaaacgtag atcattgtgg ctgcctccat tatcaggcta gcggataact ttatcaaaaa
     9961 gcgtccgtga atgaagaagc ttttttaagc gaaaaaaggt ggtaccgttc tagaatctag
    10021 agcccttttc ccaagtggaa aagggctttt tttatatttt aaggtggtgg ttttcatgga
    10081 atctgatatt aatggcatta ctaattgctg caacgtttat atcgtcaatc aaaatgataa
    10141 ttattggagg aaaaatttat ggaagaaaca aaaacttatt catggaaaca actattgatg
    10201 gtcagttcac ttatcttcgg gatgttcttc gggtcaggta atctaatctt tcctgtccac
    10261 ttaggtcaaa tggctggcac aaactgggtc agtgctggcg taggatttgc catctcaggc
    10321 gctcttttcc cattactagc tatcttagct gtagtagtga caaaaagtga tggtctgtat
    10381 gacttagcta aacctgtcgg aaaatggtat gctgccttgt tcttaatcct tgttcatttg
    10441 acgatcggac catttttcgg tacaccacgg acagctgcta ctgcttttga aatggctgct
    10501 aaaccatttt tgcctgaaaa atataattca ttaggtatgt ttttattctc tgctcttttc
    10561 tttttacttg cttatttcct tactgtccat cccacacggt tggtcaaata cgtcggaaag
    10621 tatctaaact ccttgtttct tgcattatta gcaatcattt ttgtcgtttc tttattccac
    10681 ccaatgggaa atctaaatca atctgctgca gatacttacc aaacaaacgc tttaacaaat
    10741 ggtgtcctag aaggttataa cacggttgat gcagtagctt tgcttgcctt aagtgtcact
    10801 tttgtccatg cagtccgtga ccttggtttc aaagataaaa aagtcacaga attaacagca
    10861 aaagctggta gcctgagcgt tgcgctagaa gtcatgatct attttggact tgttcttctc
    10921 ggtgcgatga gtttgaataa gatgtcttta tcagaaaatg gcggaactgc actttctcag
    10981 attactaatt tttatttagg taacttcggc gctagcttct taggagtgat ggtcacatta
    11041 ggtgtcttca ctaccgctat gggactcgtt gtttcttttg cacaagattt ccataaactg
    11101 ttccctaaag tcagttatat gacatggctg cggttaacga ctttcgtctc ttttgtcgtt
    11161 gcaaatgctg gtttggacaa tatcatccaa tggtctttac cagtattgat gcttttgtac
    11221 ccattgtcgc ttgcgttgat cttgctttcc ttaacagcaa aatttttcca aaagacacca
    11281 tttgtctatc aagtaacgat gttgtttgct gctgttcccg ccgtattgga tatgctggca
    11341 aattcgcctg ctttagtgag tcaacaaaga gttgtagcaa gcatgctcga attttatcat
    11401 catcacgttc cttttgctgc attaggactt ggctggatgg tcccaacgtt acttggttac
    11461 gctggcagct tactcttcta ttacgcctat cgcctatcag ggtacaaaca agaagcaaat
    11521 gaactaccag aagaataacc agatcaaaca caatttaaca taagaaatat taaacaggaa
    11581 aaaaccagct agatgaaaga atcctattct ttcgtctagc tatttttta
//
LOCUS       DAFEEZ010000081        11284 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000081
VERSION     DAFEEZ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.084"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            129..1175
                     /gene="gmd"
                     /locus_tag="LP245_002481"
     CDS             129..1175
                     /gene="gmd"
                     /locus_tag="LP245_002481"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HBL1520359.1"
                     /translation="MKKALITGITGQDGSYLADFLLEKGYEVHGITRRASISNTARID
                     HLMGKITLHDGDLSDSSSLIRIISIVQPDEIYNLAAQSHVQVSFDVPEYSGDVDALGV
                     MRILEACRILGLTKKTKIYQASTSELYGKVEEVPQRETTPFHPYSPYAVAKQYGFWIT
                     KEYREAYGMFAVNGILFNHESERRGENFVTRKITLAAGRIAEGLQDHLELGNMDSLRD
                     WGYAKDYVECMWMILQHETPEDFVIATGEQHTVRDFTEKAFAANGMTIRWEGTGIDEK
                     GYDVETGKMLVCVNPQWFRPTDVDNLWGDPTKAKTVLGWNPQKTSYEELVNIMAKHDR
                     ELAKREAAMKNAVK"
     gene            1255..2268
                     /locus_tag="LP245_002482"
     CDS             1255..2268
                     /locus_tag="LP245_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520360.1"
                     /translation="MATLCRCEAKITLVCGANHLDFAKRNLEQELPKELIDRVRYRPI
                     NTDIGLINREGTLLVDTGKLTEICEYFLAKVPSLAKTEAEWLKREAVSAVLCDMPIWA
                     MDACDMAGVPFLYVGNFTWTELYREFLPEHIWKEYAKRYGKIQHTMLYALNNEEMLEF
                     LQNSEKTPTSVVARPIHNDEVQRIKSQHEKPPVFVALGMSARFKQPIDVSHAPYDFIT
                     TLGVPLVGENVTVISNSTPNTQDYIAAADYVITKAGWGTVAECILAQRPMALFARDTV
                     LEDRTTICKLQKLGLAISVTPENLHRVERVIEDLKQLDTSNFDTFYDAASEIADKLIS
                     LMQ"
     gene            2305..3249
                     /locus_tag="LP245_002483"
     CDS             2305..3249
                     /locus_tag="LP245_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014424865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HBL1520361.1"
                     /translation="MMEKDAKIYVAGHRGMAGSAIVRELNRQDYNNIITRTHKELDLC
                     RQDAVEAFFAQEKPDYVFLAAAKVGGIIANQNALADFMYENMILEMNVINSAWKNGCK
                     KLQFLGSSCIYPRMAPQPMPESCLLTSELEKTNEAYALAKISGLKYCEFLNKQYGTDY
                     ISVMPTNLYGPNDNYHPTHSHVLPALIRRFHEAKEAGLPTVTCWGDGSPLREFLYVDD
                     LANLCVFLMNNYSGDETVNAGTGKELSIKELTEMVAKVIGYEGEILWDTSKPNGTPRK
                     LLDVSKATKLGWTYKTELEDGIRLSYEDFLNNPMRAER"
     gene            3317..4630
                     /locus_tag="LP245_002484"
     CDS             3317..4630
                     /locus_tag="LP245_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBL1520362.1"
                     /translation="MNIVLLSGGSGKRLWPLSNDIRSKQFIKIFKTEDGYESMVQRVY
                     RQIKKVDNDATVTIATSKTQVSAIHNQLGEDVGVSVEPCRRDTFPAIALATAYLVDVM
                     GIDPEESVVVCPVDPYVEDDYFEALKSLSDQADKGEANLVLMGIEPTYPSEKYGYIIP
                     ESAEQTAFVNTFKEKPSEAVAKEYIAQGALWNGGVFVYKLKYVMERAHQLIDFVDYQD
                     LFNKYDTLTKISFDYAVVEHEDKIQVQRFAGMWKDLGTWNTLTEGMEESIIGKGVMNE
                     NCDGVHILNELDVPVLAMGLHDVVISASREGILVSDKEQSSYIKPFVDKFEQQIMFAE
                     KSWGSYKVMDVEAESMTIKVTLNASHSMNYHSHKNRDEVWVVLAGTGKTIVDGYEQVV
                     KAGDVITMSAGCRHTIMADTELKLIEVQLGKDINVKDKQKFELEY"
     gene            4714..5616
                     /locus_tag="LP245_002485"
     CDS             4714..5616
                     /locus_tag="LP245_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HBL1520363.1"
                     /translation="MMNLQKELRCLLLRKLGMLYAPGWTELCCVWSEYQGMTLTEVLQ
                     EHPEFLGTHPQTKGELPILIKFIDAKKDLSVQVHPTDEYAIEKENGQLGKTEMWYVLD
                     ASLIYGLQKITEEAVIREAIAQGTVERYLQKVPVKKNDVFFIEAGTIHAIGAGALIAE
                     IQENSNLTYRLYDYDRVDKNGKKRELHVDKALEVANLKGLSEPKQPLRVLKYRAGVAA
                     ELLCRCKHFEVSRMIVNTERRQTVHYRADSVSFRVLLCVNGCGTVRFDNESLDIYKGD
                     CLFVPADSTEISIHGSIQFLDVRG"
     gene            5621..7273
                     /locus_tag="LP245_002486"
     CDS             5621..7273
                     /locus_tag="LP245_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBL1520364.1"
                     /translation="MNYKVEYERWLNHANADIIEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLADYLNKNYEAASVVVGYDSRIKSDVFAKTAADIF
                     AANGIQVHLWPELLPVPTVSFATRYLKADAGVMITASHNPSKYNGYKVYGADGCQITT
                     EAATAILAEIEKLDIFADVKMDGDASKIASIQSEVLTAFIEEVKGQSVLFGEKVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEIKEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKSAHGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PADPVMVKTIVTMDLGERIASNYGVRTIDVLTGFKFIGEQIGMLEKAGKADSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLLDKLNEIYTKYGYCLNTLHSF
                     EFDGAAGFTKMQEIMVEFHKGLDIIGGKKVIETLDYSKGLNGLPKSDVLKFMLEDNCS
                     VVVRPSGTEPKLKTYISVSAENKEAAEAMEAIMAAELAEMFE"
     gene            7297..8163
                     /locus_tag="LP245_002487"
     CDS             7297..8163
                     /locus_tag="LP245_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1520365.1"
                     /translation="MEELFSNALKSVKSNRVLYTASFFARSSLLYLQEIGQLTALKAH
                     TSRRTGLSSYLCFLVEVGSGTLEYKGQKYTLQVGDMVFIDCLKPYVHESSEDDLWTLR
                     WCHFNGIGMTEVYKKYLERGGQPVFKTSKTDKYADLLRSLHMVAEGQEYVRDMKINVL
                     LSELLMHLMEDSWNPDKVPNFSTKKMELQNIKQYLDDHYTEKITLDQLSAEFFINKQY
                     LAKIFRETYGTTVVGYLNQKRITQAKHLLRFTNLSMEEIATKIGITDANYFSRTFFKV
                     EGVRPSEFRKMW"
     gene            complement(8205..8396)
                     /locus_tag="LP245_002488"
     CDS             complement(8205..8396)
                     /locus_tag="LP245_002488"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520366.1"
                     /translation="MIIRDDHIYTCDSCHYSFPADEQPERCPDCGKTATRLDTEIETE
                     DYYRVRAEIKAEIKALNAG"
     gene            8426..8965
                     /locus_tag="LP245_002489"
     CDS             8426..8965
                     /locus_tag="LP245_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520367.1"
                     /translation="MQLLLYRIGDSTKIRFLINVRFRVIYSTVLPKGIPQRQKWMIHM
                     EEIMQMILGNAKFQLGQVVSTPAVLETFNPLQTANGIPEALSNLWFRQEISIAEIEDA
                     VLDAKNGKELANSLNRIKLFRKFTLDRELDGMVRLKGADVWKNISYLKVYTATPPKKP
                     TPPRFQSNGWSLFFSHKSA"
     gene            9093..9446
                     /locus_tag="LP245_002490"
     CDS             9093..9446
                     /locus_tag="LP245_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520368.1"
                     /translation="MAMSEKAKKYLKEIKGAKTIPELKDVEIAIKRDGILAWAEFTKL
                     NEAVEEKKVALRKKKQETSLQEILFWAYKKESDKLLKMMDEGADKDAIQMQVQRYDSI
                     GQIIAEADLEDEYEV"
     gene            9913..10389
                     /locus_tag="LP245_002491"
                     /pseudo
     CDS             9913..10389
                     /locus_tag="LP245_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290865.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
     gene            10389..10583
                     /locus_tag="LP245_002492"
     CDS             10389..10583
                     /locus_tag="LP245_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520369.1"
                     /translation="MAETRPKGYPKLKEYTPNRFMLSECHYDKARADRAVNFIGQLRH
                     TKGKWAGNRFWLLPWQEQII"
     gene            10589..10874
                     /locus_tag="LP245_002493"
                     /pseudo
     CDS             10589..10874
                     /locus_tag="LP245_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
     gene            10888..11254
                     /locus_tag="LP245_002494"
                     /pseudo
     CDS             10888..11254
                     /locus_tag="LP245_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387104.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
BASE COUNT         3168 a         2308 c         2865 g         2943 t
ORIGIN      
        1 atattgtgct aatgcgtgcg tagattgttc tatgaaatat cgaaaattat cgtgtattct
       61 tgaaaagtat tagaaattac gagccattta tatggtctta tcacttacat aggaaaggat
      121 aatgtatcat gaaaaaagcg ctgattactg gtattactgg tcaggacggt tcctatctgg
      181 cagatttcct gctagagaag ggctacgaag ttcacggtat cactcgccgt gcttctattt
      241 ccaataccgc tcgcattgac catttgatgg gcaagatcac ccttcatgac ggtgacctgt
      301 ccgactcatc ttctctgatt cgtatcatca gcattgttca gcctgatgaa atctataacc
      361 tcgctgcaca gagccatgtt caggtttctt ttgatgttcc tgagtactcc ggcgatgttg
      421 atgctttggg cgttatgcgt attctggaag cttgccgtat tctgggcctg acgaagaaga
      481 ctaagattta tcaggcatct acttctgagc tgtatggcaa ggttgaagaa gttcctcagc
      541 gtgaaaccac tccgtttcat ccttacagcc cttatgctgt tgcaaagcag tatggcttct
      601 ggatcactaa ggaatatcgt gaagcttatg gcatgttcgc tgtcaacggt attctgttca
      661 accatgaatc cgaacgtcgc ggtgagaatt tcgtcacccg taagatcacc ctcgctgccg
      721 gccgcattgc agaaggcctg caggaccatc tggaactggg caacatggac tccctgcgtg
      781 actggggcta tgcaaaggac tatgttgagt gcatgtggat gattctccag catgagactc
      841 ccgaggactt cgtgatcgct accggcgagc agcacactgt tcgtgacttc accgagaagg
      901 cattcgcagc aaatggcatg accattcgtt gggaaggcac tggcattgat gaaaagggct
      961 acgatgttga aaccggcaag atgctcgttt gtgtaaatcc acagtggttc cgtccgactg
     1021 acgttgacaa cctgtggggc gacccgacta aggcaaagac cgttctcggt tggaatccgc
     1081 agaagacctc ttacgaggaa ctggttaaca tcatggcaaa gcatgaccgt gaattggcaa
     1141 agcgcgaagc tgcaatgaag aacgcagtca agtaagctga cattgaataa acatatctgt
     1201 ttctatcttt ccagtcacgg cttcggacat atcgcgcgga atctgcccat tattatggca
     1261 acactctgcc gatgcgaagc gaagattaca ctggtttgcg gcgcaaatca tctggatttt
     1321 gcaaagcgca atttggagca ggaactgccc aaagagctga tagaccgcgt gcgctatcgt
     1381 ccaataaaca cagatatcgg tctgattaac cgtgagggca ccctactggt ggacacgggt
     1441 aagctgaccg agatctgtga atattttttg gcaaaggttc cttctttggc aaagacagaa
     1501 gccgaatggc tcaagcgaga agctgtcagc gcagtgcttt gcgatatgcc aatctgggca
     1561 atggatgcct gcgatatggc aggagtacct ttcctgtatg taggaaactt cacttggaca
     1621 gagctgtatc gcgaattttt acccgaacat atttggaaag aatatgccaa gcgttacggt
     1681 aaaattcagc acaccatgct ttatgcgcta aataacgaag aaatgttgga atttctccaa
     1741 aacagcgaaa aaacaccgac ttccgttgtg gcgcgtccga ttcataacga cgaagtgcaa
     1801 cgcattaaat cacagcatga aaaaccgcct gtatttgtcg cactcggtat gtccgcgcgg
     1861 ttcaaacagc caattgatgt cagtcacgcg ccgtatgatt tcattacaac gctaggtgtt
     1921 ccgcttgtgg gagaaaacgt aaccgttatt tctaacagca cccccaatac acaggactat
     1981 atagcggcgg cagattacgt tattacaaag gctggatggg gaactgttgc ggagtgtatt
     2041 ctcgcacagc gtccgatggc actgttcgcc cgcgatacag ttttggaaga tagaacaact
     2101 atttgtaaat tgcaaaaact gggtctggca atttccgtca caccggaaaa cctccaccgc
     2161 gtagagcggg tgattgagga cctcaaacag ctagacacct caaattttga tacattttat
     2221 gatgctgcga gcgaaatcgc agacaaattg atttctctca tgcaatgaga gatgctctaa
     2281 atttagaaag gagcaagcat tattatgatg gaaaaagacg caaaaatcta cgtagccggt
     2341 catcgtggca tggctggttc cgcaatcgtg cgcgagctga accgtcagga ctacaacaat
     2401 attatcaccc gcacccataa ggagcttgac ctgtgccgtc aggacgctgt tgaagcattt
     2461 ttcgcacagg aaaagccgga ttatgtattt ctcgctgctg caaaggttgg cggtattatc
     2521 gcaaaccaga acgctctggc agacttcatg tatgaaaaca tgattctgga aatgaacgtc
     2581 atcaactccg catggaagaa tggctgtaag aagttacagt tcctcggttc ttcctgtatc
     2641 tatccgcgta tggcaccgca gccgatgccg gaaagctgtc tgctgacaag tgagctggaa
     2701 aagaccaacg aggcttatgc actggcaaag atttctggcc tgaagtactg tgagtttcta
     2761 aacaagcagt acggtactga ctatatctct gttatgccta ctaacctgta tggacctaac
     2821 gacaactatc atcctactca cagtcatgtg ctccccgctt tgattcgtcg cttccatgag
     2881 gctaaggaag caggtctgcc tactgttacc tgctggggtg atggttctcc tctgcgcgaa
     2941 ttcctatatg ttgacgatct ggcaaacctg tgtgtgttcc tgatgaataa ctatagcggt
     3001 gacgagactg ttaatgcagg tactggcaag gaactgtcta tcaaggaact gaccgagatg
     3061 gtagcaaagg ttattggtta cgaaggcgag attctgtggg ataccagcaa gccgaacggt
     3121 acacctcgta agctgctgga tgtttccaag gcaaccaagc tgggatggac atataagact
     3181 gagttggaag atggcatccg tctgtcctac gaggacttcc tgaataaccc gatgcgtgct
     3241 gaacgctaat ttaccgaggt tgctgtgatt tttgaggatt gcagcagcct ctttcttata
     3301 aaaaggagag atcattatga atattgtttt actgtctggc ggttctggta agcgcctttg
     3361 gccgctgtct aatgacatcc gttccaagca gttcattaag attttcaaaa ctgaagatgg
     3421 atatgaatcc atggttcagc gtgtctaccg ccagattaag aaggtagata acgacgcaac
     3481 tgttacgatt gcaacctcta agacacaggt ttctgctatc cataaccaac ttggtgagga
     3541 tgtgggtgta tctgtagagc cttgtcgccg cgataccttc ccggcaatcg cattggctac
     3601 cgcttatctg gtagatgtga tgggcattga tccagaagag tccgtagttg tttgcccggt
     3661 tgacccttac gtagaagatg actattttga ggccctgaaa tctctgtccg atcaggctga
     3721 caaaggcgaa gctaatctgg tgctcatggg tattgaaccg acttatcctt ccgagaagta
     3781 cggctacatc attcctgaga gcgcagagca gactgctttc gtaaatacct tcaaggaaaa
     3841 accttctgag gctgtggcaa aggaatatat cgcacagggt gcactgtgga acggtggtgt
     3901 gtttgtctac aagctgaagt atgtcatgga gcgtgcacat cagctgattg actttgtaga
     3961 ttatcaggat ctgttcaaca aatacgatac tctgactaag atttccttcg actatgccgt
     4021 tgttgagcat gaggacaaga ttcaggtaca gcgttttgct ggtatgtgga aggatctggg
     4081 gacttggaat actctgaccg aaggtatgga ggaatccatt atcggtaaag gtgttatgaa
     4141 tgagaattgc gatggcgtac acatcctgaa cgaactggat gttcctgtgt tggctatggg
     4201 tctgcatgat gtggtcatct ctgcatctcg ggaaggtatt ctggtttccg ataaggaaca
     4261 gtccagctat attaagcctt tcgttgacaa gttcgagcag cagatcatgt tcgcagagaa
     4321 gtcttggggt agttataagg ttatggatgt agaagcagag agcatgacca ttaaggttac
     4381 tctgaatgct agtcactcca tgaattatca cagccacaag aaccgtgacg aggtgtgggt
     4441 ggttctggcc ggtactggta agaccatcgt ggatggatat gagcaggttg ttaaggctgg
     4501 cgatgtgatc accatgagtg ctggctgtcg gcataccatt atggcagata ctgagctgaa
     4561 gctgattgaa gtacagcttg gcaaggatat caatgttaaa gataaacaga aatttgagtt
     4621 agagtattaa aaaacggagg agggctcgtt atacagaaac cgtttttatt gaagccttcc
     4681 gcaaaggatt atctgtgggg gggaaccgcc tgaatgatga atttgcaaaa ggaattgaga
     4741 tgtctcctct tgcggaaact tggaatgctc tacgcacccg gatggaccga gctttgttgt
     4801 gtctggtcag agtatcaggg gatgaccttg acggaggtgt tgcaagaaca cccagagttt
     4861 ctgggaacgc atccgcagac caaaggagaa ttgccgatcc tgatcaaatt cattgatgcg
     4921 aaaaaggatt tgtctgttca ggtacatccc acagatgaat atgcaattga aaaagaaaac
     4981 gggcagcttg gaaagacaga gatgtggtat gtactggatg ccagcttaat ctatgggctg
     5041 cagaaaataa cagaagaagc tgtgatccgt gaagcgattg ctcagggaac tgttgagcgt
     5101 tatcttcaga aggttccggt caaaaagaat gatgtgttct ttattgaggc gggaacgatt
     5161 catgcgattg gtgcgggtgc actaattgca gaaattcagg aaaattccaa tctgacttat
     5221 cgtctctacg attatgaccg tgttgacaaa aatggtaaaa agagagaact tcatgtagac
     5281 aaagcgctag aagtagcgaa cttgaaaggg ttgtcagaac cgaaacagcc gcttcgtgtt
     5341 ctaaaatatc gtgctggtgt agctgcggaa ttgctttgca gatgcaagca tttcgaggtc
     5401 tctcgtatga ttgtcaacac tgagagaaga cagacggtac actatcgtgc ggattcagtc
     5461 agcttccgtg tgttgctgtg tgtcaatggc tgtggtaccg ttcgatttga taatgaatcg
     5521 ttggacatct ataaggggga ctgccttttt gtgccggccg attctactga aatcagcatt
     5581 cacgggtcga ttcagtttct ggatgtgaga ggataataat atgaattata aagtagaata
     5641 tgagcgttgg ctgaatcatg ccaatgcaga tattatagaa gaactgcgtt cctattctga
     5701 gaaggacatt gaggactctt tctataaaaa tttgtctttc ggtactggtg gtctgcgtgg
     5761 taccatcggt gcaggcacta atcgcatgaa cgtacacacc gtaggtaagg caagccaagg
     5821 tctggcagac tatctgaata agaactatga agccgcttcc gtggtggttg gctatgattc
     5881 ccgtatcaaa tctgatgtgt ttgcaaagac tgccgcagac atctttgctg caaatggtat
     5941 tcaggtgcac ttgtggccag aactgcttcc tgttcctaca gtatcttttg cgactcgtta
     6001 tctgaaggca gatgccggtg ttatgattac ggcatctcat aacccttcta aatataacgg
     6061 ctacaaggta tacggtgcag acggctgtca gattactacc gaggctgcta ctgcaattct
     6121 ggcagaaatc gaaaagctgg acatctttgc tgatgtaaag atggatggcg atgcttctaa
     6181 gattgcatcc attcagtcgg aagttctgac tgctttcatc gaagaagtga aggggcagtc
     6241 cgtcctgttt ggcgaaaaag tggacaagaa tgttgctatc gtgtattctc ctctgaatgg
     6301 taccggtctg gtgcctgtta cccgcaccct ggcagagatg ggatacagca atgtgaccgt
     6361 tgtggaagaa cagcgtctgc cggacggtaa tttcccgact tgtccttatc cgaaccctga
     6421 aattaaggaa gctatgtctc tgggtatgga gtatgccaag aagtacaatg cggatctgct
     6481 gttggccact gaccctgact gcgaccgtgt tggtatcgca gttaagagcg cacatggtga
     6541 ctatgttctg ttgtctggta atgagactgg tctgctactt ctggactaca tctgttctca
     6601 gagaattaag catggaaaaa tgcctgctga ccctgtgatg gtcaagacca tcgtcaccat
     6661 ggatttgggt gaacgtatcg catccaacta tggtgttcgt accatcgatg tgctgaccgg
     6721 ctttaagttt atcggtgagc agattggtat gttggaaaag gctggtaagg ctgacagcta
     6781 tatcttcggc tttgaggaat cttacggcta tctgtccggt agctatgtcc gtgacaagga
     6841 cggtgttaac gctgcttatc taatctgtga aatgttctct tactacaaga ctcagggtat
     6901 cagcctgctg gataagctga atgagattta tacaaagtat ggctattgtt tgaacaccct
     6961 gcattccttc gagtttgacg gtgcggcagg ttttaccaag atgcaggaaa ttatggttga
     7021 attccacaag ggtctcgata taattggtgg taagaaggtt attgaaactt tagactacag
     7081 taagggcctg aatggtctgc cgaagtctga tgttttgaag tttatgctgg aagataactg
     7141 ctctgttgtg gttcgtcctt ctggtactga gccgaagctg aagacctata tcagcgtcag
     7201 cgcagagaac aaggaagccg ccgaagctat ggaagctatt atggctgctg aactggcgga
     7261 aatgttcgag taagaaaaga aaggagaaat cttgtaatgg aggaactgtt ttctaacgct
     7321 ttgaaatcgg tgaagtcaaa tcgtgtgctg tacacggcat cgttctttgc aagatcctct
     7381 cttttgtatt tgcaggaaat tggacagctg actgctctga aggcacatac atctaggcgt
     7441 acaggattgt catcttacct ttgtttcctg gtagaagttg gttcaggcac attggagtat
     7501 aaggggcaga aatatacgct tcaagtagga gatatggtgt ttattgactg tttgaagccg
     7561 tatgtccatg agtcatcaga agatgatttg tggactttgc ggtggtgcca ttttaatggc
     7621 attggtatga cggaagtcta caaaaaatac cttgaacgag gtggtcaacc ggtctttaaa
     7681 acatcaaaaa cagataagta tgctgacttg ctgaggagcc ttcatatggt ggcagaggga
     7741 caggagtatg tccgggatat gaaaatcaat gttctactca gtgaactgct gatgcatttg
     7801 atggaagatt cttggaatcc tgacaaagtg ccgaatttct ctacaaaaaa aatggaattg
     7861 cagaacataa aacaatatct ggatgaccat tacacggaga agattacgct ggatcagttg
     7921 agtgcagagt tttttatcaa taaacagtac ttagctaaga tttttcgtga aacttacggt
     7981 acaactgttg tcggttatct gaatcagaaa cgaatcacac aggccaagca cttgctacgc
     8041 tttacaaatc taagtatgga agagattgca acaaaaattg gcataacaga tgcaaactat
     8101 ttttccagaa cttttttcaa ggtggaaggt gttcgtccca gcgaattccg caagatgtgg
     8161 taataaaaag ccggcggtgt tgagccgccg gtcagtacct gtcgttaacc cgcattcaaa
     8221 gctttaatct cagctttgat ttcagcacga acacgatagt aatcttcagt ttcgatttcg
     8281 gtatccagcc gagttgctgt ctttccgcag tcaggacaac gctctggctg ttcgtcggca
     8341 gggaagctgt agtggcagga atcacaggtg taaatgtgat cgtcacgtat aatcatcacc
     8401 taccaatcca gtgcttagat ttttcatgca attactatta tatcgaattg gtgattccac
     8461 aaaaatccgc ttcttgataa atgtacgatt cagagtgata tatagtactg tactgccaaa
     8521 gggaatacca caacggcaga aatggatgat tcacatggaa gaaattatgc agatgatttt
     8581 agggaacgca aaattccagc tcggacaggt ggtttcgacc cctgctgtat tggaaacttt
     8641 caaccccctg cagaccgcaa acggcattcc cgaagccttg agcaaccttt ggtttagaca
     8701 ggaaattagt attgcggaga tcgaggacgc agttctggat gccaagaacg gcaaggagct
     8761 agcaaacagc ctcaaccgca tcaagctttt ccgcaagttc accctcgacc gagagctgga
     8821 cggcatggtc agactgaagg gcgcggacgt ctggaagaac atcagctacc tcaaggtcta
     8881 caccgccacg ccgcctaaga aaccgacccc cccaaggttc cagtcgaacg gctggagcct
     8941 tttcttctct cataaatcgg cataatgtat acaaatacag ctccaaatga ttgtgtagta
     9001 tatgcctgtg gattgacttg atatagtcga gagactatgg caatatacac acaaccaaag
     9061 gggaaaatcc caaaaacaag gaggaaacgc taatggcaat gagcgaaaag gcaaagaaat
     9121 atttgaagga gatcaagggt gcaaagacca tcccggagct gaaggatgtg gagatcgcaa
     9181 tcaagcgaga cggtatcctt gcttgggcag agttcaccaa gttgaacgag gcggtggaag
     9241 agaagaaggt cgcccttcgc aagaaaaagc aggagaccag ccttcaggag atccttttct
     9301 gggcctacaa aaaggaatca gacaagctgc tgaagatgat ggacgaggga gcagacaagg
     9361 atgccatcca gatgcaggtc cagcgttacg acagcatcgg ccagatcatt gcagaggcag
     9421 acctcgaaga tgagtatgag gtttgagaat acagcctgaa ccactaagaa ccaaataccg
     9481 aaagggactt ctgaaacaga cagaggtccc tttcttttgc tcactttggc ggtcaattat
     9541 gaaccaaaaa ccagtcgaat gattgtgtac attatggctt tcaaacgact tgataataat
     9601 cacttttaga gtgatatatg tactacaaaa aacaaaagac tggagaaaac aacagatgag
     9661 cgaatacaga atcatttata tcagcgacga ggacggcggc gaggtggaag gatgtggcta
     9721 cacggctacg atggttatga tgcggtcaga aacttcttgg aatttgcctg cggcatcttg
     9781 aaaatcctgc gggtgcgatt catcagaaga gtggactgaa atacaagtta gcagatagag
     9841 aagagagtca ggtttcgact tggctctgtt ctctgtctac tggcagaaat acattgaagg
     9901 gaggtgacga ctgtggcaac cagaggaaga aaatcaaccc cgacagccat gaagaagctg
     9961 gagggaaatc cgggcaatcg cccactcaat gcaaaagagt caacgccgga aaagaaggca
    10021 ccgacctgtc cgaagtggct ggaaccagag gcaaagaagg aatggaagcg tctggcaaag
    10081 cagatggagg ccatcggaat cttgacagat gtggatatgg ctgcctttgc cggttagtgc
    10141 caagcctacg cccgctggaa ggaagccgag gaattcatta cccagcacgg tatcatcgtg
    10201 aaaaccctat ccggctattg gcagcaggta ccacaggtgt ttattgccca gacctatctg
    10261 aaaattatga accgattttc cgagcagttc ggtctgacgc cttcgtccag aagccgtatc
    10321 attgccggtg atggcggtgg tgtcggagca gaagatgcga tggaggctct gttgggaggt
    10381 ggtagctgat ggcagaaacc agaccaaagg gctatcccaa attaaaggaa tacacaccaa
    10441 accgattcat gctttcggaa tgtcactacg acaaagccag agcggatcgg gcggtgaact
    10501 ttatcggaca gctccgacac accaaaggca aatgggcagg caaccgcttc tggctcttgc
    10561 cttggcagga acagatcatc tagtgtaatc tcgcttaact gtattaacgg acgtagcgac
    10621 tttattaaga gtgttcatgg taggagcatt agttgcaaca atgattgata ttaaattttt
    10681 atggtaccaa cgattggcga tgtgacattg aatatgcaaa actatatcga tatgatatta
    10741 tctaaaatct tactcgctgg gatcgtcgag gtgtttattg gttgttagga aagaaaaata
    10801 tgacccaact cgagcgattt ttatcgtatt acttgtgtgt ggctttatct gcattgtgtg
    10861 tgatttcgaa ataagggaga gccaaaaatg agtagaaaat tgatattgat tagtcacgga
    10921 aaattttgtg aggaattgaa aaaaagtaca aaaatgatta tgggacctca agagaatatc
    10981 tacacgttac ctttattacc agaagatggc actgaaacat acagacaaaa gctcttactg
    11041 tcatagattc gttaaatgat tttgtggtac tatgcgatct tttaggcggt acacctacta
    11101 atatcatttc taaactgata atggaaggac aacagattaa actttatgtc ggattaatct
    11161 tcctatggtc attgaattta tcaactcgca agtgattggt tcagagcccg agtttgttcg
    11221 tgcaggatgt gaaagcattg tatctgtcaa ctaattaatt agtggaatag tagaagatga
    11281 agag
//
LOCUS       DAFEEZ010000082        10979 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000082
VERSION     DAFEEZ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.085"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(58..1434)
                     /locus_tag="LP245_002495"
     CDS             complement(58..1434)
                     /locus_tag="LP245_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBL1520370.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(1562..2680)
                     /locus_tag="LP245_002496"
     CDS             complement(1562..2680)
                     /locus_tag="LP245_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL1520371.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            2822..3256
                     /locus_tag="LP245_002497"
     CDS             2822..3256
                     /locus_tag="LP245_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1520372.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(3334..3867)
                     /locus_tag="LP245_002498"
     CDS             complement(3334..3867)
                     /locus_tag="LP245_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBL1520373.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(3961..5139)
                     /gene="mutY"
                     /locus_tag="LP245_002499"
     CDS             complement(3961..5139)
                     /gene="mutY"
                     /locus_tag="LP245_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBL1520374.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(5132..5929)
                     /gene="recX"
                     /locus_tag="LP245_002500"
     CDS             complement(5132..5929)
                     /gene="recX"
                     /locus_tag="LP245_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBL1520375.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            6036..7418
                     /gene="rlmD"
                     /locus_tag="LP245_002501"
     CDS             6036..7418
                     /gene="rlmD"
                     /locus_tag="LP245_002501"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBL1520376.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(7592..8170)
                     /locus_tag="LP245_002502"
     CDS             complement(7592..8170)
                     /locus_tag="LP245_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBL1520377.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            8492..8962
                     /locus_tag="LP245_002503"
     CDS             8492..8962
                     /locus_tag="LP245_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBL1520378.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(9070..10296)
                     /locus_tag="LP245_002504"
     CDS             complement(9070..10296)
                     /locus_tag="LP245_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL1520379.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         3277 a         2190 c         1844 g         3668 t
ORIGIN      
        1 gaaaagacgt gttgcttgtt tattcaagca acacgtcttt cataaccaag tttccaatta
       61 tcttcttggc tcgtcatctt cgaattcttt tctgaagtat cttcgttctt cttcaggttc
      121 cgcttctgtt tcttccggat catgaaaaat gacacggatt ttaaggattc gagaaccttc
      181 catttcttca gaaaccagcg taatattatc gacatcaaac gataactttt cgccttcatc
      241 cggaatcatg cctaatgctg taatcaaata accagccatc gtatctacat cactcatatg
      301 cagatcactg tcaaaagctt cattgaactc atcaatcagc atacgtcctt ggatgatata
      361 ttcgtgttca tcgatttttt cataaagatt ctcaacttca tctgattcat catcgatttc
      421 tccgacgatt tcttctaaaa ggtcttctag tgttgctaac ccaacgacgc cgccatattc
      481 atctaataaa atagccatct gattctgcgt ctttttcatt tcatataaca gatcatcaat
      541 aaagaccgtt tcaggaacga ataaaggctc ctgcatgatt ttcttgatat ctaaattatc
      601 aaagccgaat ttatgggcag cttttagtaa attctttgta tgaaggattc cgactacttt
      661 atctttgtct tcgttataaa cagggattct tgaatagttt tcggataaaa cttcattcac
      721 attttcttcc acagtgtcgt tgatatcaat cataaatgca tccgttcgtg ggaccatgac
      781 ttctcgggca actttcgtat caagagaaaa aaccccttgg agcatttcta attcttcatt
      841 attcaatacg ccttcgtttt caagcatata acgcatttca tctctggtca tttttgaatc
      901 ttcatcatca aaagtcatcg gcgtgatacg cgccaataaa cttgtggaag cagaaagcag
      961 ccagacgaag ggcttagcta ctacaccaat caagcgtatc agccctgaag tgaactttgc
     1021 gacttcttct gatttattta aagcaatacg tttagggtac aattctccaa aaacaatcga
     1081 tacataggtc aaaatagcca gcacaatgat atttgcaata ttttttgccg ctgtgccgcc
     1141 acctaatacc ggagctaacc gttccgataa agtattagct agtgaagcac cagacaaaat
     1201 gttgaccaaa gtgattccta cttggattgt cgataggaaa ttatttggat tctgcaatat
     1261 ttttaaaagc ttttgagatt tcacatctcc ttcatcagct ttttgctcga ttcgattctt
     1321 attgatcgaa acaacagcaa tttcggaagc tgctaaaaaa gcattgatca atgtcaaaac
     1381 gatcaataat aaaatctgcg ctaacagcga ctgactctca gggtcagcat tcataatcgc
     1441 attctctcct tataaaatta atttttagtt tacgatagaa aaaaacgtgg cactatagcc
     1501 acgttaaaat ggtatcacaa agcaattttc tttgcaataa aaacaagtgt actaaaacta
     1561 cctacgaggt cgtagcaatt ttcttcttgt tttcattttg cttgtcttct ttgacgattt
     1621 tgattatata ggaaatgatc gtcttgcaga ttgcgtaaaa aggaacacct aagaagatac
     1681 caagcaatcc ggcaatattt ccagctacta gaagaacgat aatgatcgtt aatggatgga
     1741 ttttcagtga tttcccaatt acattaggat aaatgatatt cccatccaac tgttggacga
     1801 ttagcacaac cacacaacaa agtaatgctt ttaccggatc attgaagact gttactagaa
     1861 atgcaggtgc tagtcctaga taaggtccta aatatggaat taggtttgtc aatcccgcaa
     1921 tgaccccaaa taagaaagca taatccacac caattaccat atatcctaaa aatgtgaagg
     1981 taccaacgaa taaacattcg attgcttgtc cgctaatgta attagccaat gttttattca
     2041 gttgccccaa taactccaca atttggtttc ttcttttttc tgggaaaaac tgttggatgt
     2101 ttggcactag tttttctccg tctttcaaca tatagaacaa gatgaatggt gctgtaatga
     2161 ttactacggt tgccgaagcg atcgttccaa cgatcgaacc taaactattg gatactccac
     2221 taaggaattg ctgaatgatt gtcccgtaag aaatgtctaa ttgctcaaaa tatttattga
     2281 tatctacttc cttgaacaaa ggcaattcgg ctacctcttt taaccagctt tctacctgtt
     2341 tgatgaaatc aggcatatta gatgccaatg aggaaatttg ctgtactaga cttgggatga
     2401 cactaagtaa aatccaaata attgctgcaa ctaaaaggag cagcacaatt gcgacagccc
     2461 atattctttt gatttttgct ttcatcaaca gcttgacaat aggattcaat aaatagtaaa
     2521 gaaagcctgc aatcagtaca ggtgcaaata acgtggaaaa aaatgtcccg atcggttcga
     2581 aaataaagtt tatttctgat gaaatcatga tcaatgcagc tatgatcaat aattcaagcg
     2641 accaaaacat tagtttagac tgtctaagtt tttcaaacaa tagatttcct cctttctttc
     2701 ttactagtat atattatatt cgttaaaaat tcttttattc tttttttatt tttgaaaact
     2761 tgccatactt tttatttgtt ttattttcca gtatactata cgaaaggaag gtggctagac
     2821 catgaaagtt gtacaaacaa aagatacaat gagcaatatt tacttagatg ctgtacggat
     2881 caggcatcaa gtttttgtag tcgaacaggg tgtgcctttg tctcgagaaa tagacaaaga
     2941 tgaagcccat tgtatccact tcgtcctgta ctcagataaa aaagaaccgc aaggaactgt
     3001 acgtcttttg cctttagaaa acggaaaaat gaaattacag cggatggcga ttctttctga
     3061 atacagacac caagggttag gaaaaatatt gattgaagaa gcagaaaact ttgctaagaa
     3121 tcaaggctat aatacgattt tattaggggc acagtccaca gctgaaactt tttacgaaaa
     3181 actaggatat acagcttacg gcgatccttt tgaagatgct ggcatgcctc atatttatat
     3241 gaaaaagact ttataaaaat ttatttcgaa aaaagcaaaa aacagcaagc ttttgagaaa
     3301 aatctctcac tggcttactg ttcttttttg tgtttactta cgcgacaatt gcttgtaacg
     3361 gttataccaa atatcaatat agccttccga gaacgggcca tctccattat tgatccagtc
     3421 aaccagaatc ttcacatttt cttttaggat gaagtcaata tcgttcgggt aattcatcat
     3481 tttgctgtgc atctcatatt catcgacatc caatagtcgt ttctcgccgt caggaaatac
     3541 cttgatatcc aagtcatagt cgatatattt caaggcctca tcgtccagca aaaaaggtga
     3601 agctagatta caataatagg aaaccccctt ttctctgatc attgctatta cattgaacca
     3661 gtatttttta tgaaaataaa caatcgctgg ttcgcgcgtt acccatcggc gtccatcaga
     3721 ttcagtgact aatgtgtgat cattcacgcc gatcatagag tgttcgcttg tttttaatac
     3781 catggtatct cgccacgttc gatgcaattt gccgtcgtgc ttgtaacttt ggatcgtcac
     3841 aaactctcct tcttttggaa ctcccatagc aacccttcct taagcagcat tttgtgcttt
     3901 gtgtttgggt gttcattaca ccgacatcat aattattata tcaataaaaa tgagctttgc
     3961 ctagaaagga ttcctattgt ttcgattttt ctctaactga tctaccagtt tcatttggac
     4021 cttaggaaaa acgaccgaat caaatgcatc aggcttcaac cacttcgaag ttttgttctc
     4081 ggtaaattct tgttctgctc cctcggttgc ccgtccgtaa aaaaggagaa catgccattt
     4141 cagatgacta aaaatatgag taacttctcc taaatgtcgt gtctgccaaa caaagagttc
     4201 ctgcttttca aatgggagat tttgctcttc ttctgctact aggtcatcaa acagatcgat
     4261 ttctggcttt gtttcccatt cttttttcaa tcgctcatac tcctcttgtg tcacttccat
     4321 cattggaaat gtccacatat tcgccagcaa tttttggcta tctctttctt caaaataata
     4381 cgctccagaa tgattttgaa gagctgcact gatataataa acgtcttttg gctttgcttt
     4441 ttttgttttt acaggaaaac tcgtttggat tcctcgtttg ttagctaaac aaaaggcttg
     4501 gatcggacaa gtctcacact ttggagaagt tggtgtacag atagctgaac ctagatccat
     4561 cattgcttgg ttgaattcac ctggatgctt ttcatcaatg attttccgca tcgcttcatc
     4621 aaagattttc ctgctagaag cttttgcgat gtctgcttca atgcaaaaca atctgctgac
     4681 tactcgcatc acgttgccgt caactgcagg ttctggaagt ccaaatgcga tacttgcaat
     4741 cgcgcctgtc gtatatggtc ctattccctt caatgagcta atttcttcag gcgtttgcgg
     4801 catttcccca tcaaattctg acatgatctg tttagcagca gcttggatgt tccgggctct
     4861 tgagtaataa ccaaggccct cccatgcttt taaaagcttt tcttctggag catttgctag
     4921 ctcttcaatt gtaggaaacc attccatgaa acgataaaaa taatcgatca ctgtgtctac
     4981 tctggtttgc tgaagcatga tctcagagat ccagatacga taaggatcac gattatagcg
     5041 ccaaggcagg tttctttttt cttgttcata ccattgaatg aactgatctt gaaattcttt
     5101 tgtttcttta tctgtccatt tttcccattc tttattcact ttcctcttcc ttttccgtaa
     5161 tgaatcgctg gatcatatcc aaatcaaatc ctttttgata taagctttgc tttactttta
     5221 gatttctttt tttaggttca aaccttaaat ttcttcgcca tagtttatct ccttgtttga
     5281 ctaaataatc atattctatt tcttgatctg cttcttgcgg aagatcagct atcgcttgtt
     5341 ggatcacttc ttgagaaaag cctttcgtca tcaatgtttg ttggattttt ctcaataatt
     5401 ctttttggct ttttccgtga ttttttccaa acgctttttc ggctgtctga tgtgcatttt
     5461 gaacttggtc ttcaaatgta tattggctga gcgcttgttc aatgatttca ggtttcaaac
     5521 ctttttgctg catctgctgc gctaatttct ttggtccttt gtcacttaag cgcatattcg
     5581 tgcgcacata actttcccca tagaccaaat catcgacaag gtccaattct tttaagcggg
     5641 ctacgatttt atttcgatct tcttgaagga tttccttttc ttttaagtat gttcggattt
     5701 ctttttccga tcgcaactga taacttaagt aattcattgc taggtgaaaa ccgaaatcag
     5761 ctccgctact cttcttgatc tcttggatag tttcttcgtc taattcccgt ccttttaata
     5821 atcgatagcg tactaataca tcttcagata cttgtaaagc ttctccttca gataaatcta
     5881 cgcgatagaa agggcctttg cctttactga ttctcgtaac ggttaacata aacatcctcc
     5941 tcgaacatat attctctatc ataccacaga aaatccccgt aatcaggtat tatatgttag
     6001 aataaaccac agaaaaaaga aaaagggaga tacttatggc agaaacaatt gtcaaaactg
     6061 gacaaacggt tcctttgaaa atcaagcgtt taggcataaa tggtgaagga atcggttatt
     6121 tcaaacggtt gatcatattt gttccatatg cactaccaaa agaagaagta ctagtgaaaa
     6181 tcacgaaagc aactcctcgc tatgcagaag gagaattaat aaaagtcaaa aaaacaagca
     6241 aagatcgcgt agtggcacca tgtcctgttt actatgaatg cggtggctgt caattacaac
     6301 acttagctta tcaagctcaa ttggatttta aaaaggatct gcttttgcaa gcattggaaa
     6361 aattcaaacc agcaggcttt cgatcttatc aacttttgcc gacgatcggg atggatgagc
     6421 cttggcatta tagaaacaaa gcacaatttc agttacgaaa aaataagcag actcaaaaaa
     6481 ttgaagctgg tttatacgaa gcaaactctc atcagttagt ccctataaca gactgcttgg
     6541 ttcaagaacc tcgaacacaa aaagtaatga atactgttgt tcaactattg aataaatttg
     6601 atgcacccat ctatgatgaa cggacaaaca gtggaatctt ccgcacaatc atggttagaa
     6661 tcggcgttaa aactggggag ttacaagttg tttttattac tcgcagtaaa aaattcccgc
     6721 aaaaaaacgc aatgatccgt gagatcaatg aacgactgcc cgaagttgtt tcaatcatgc
     6781 aaaatgtcca ggcacaaaaa acgtctctcg tgatggggga tgaaacgatc cacttatggg
     6841 gaaaagaagc cattgaagaa caaatcaatg aagtgacttt cgatctttct cctcgtgcct
     6901 tctttcaact caatcctcag cagaccgaat tgctttatgg cgaaggaatc aaagcattag
     6961 atgtccagcc taatgaaacg atcgtggatg cttattgcgg agttgggacg atcggcttaa
     7021 gtgtagcaaa acaagccaaa gaagtacggg gaatggatac cgttcctcaa gcaatcgctg
     7081 atgcaaaaaa aaatgcggaa agattaggat atcacaacac tcgatatgaa gtcgggacag
     7141 cagagcaagt tctgcctaaa tggttgaatg aaggttttca gcctgatggt atcatcgtag
     7201 atccaccacg tacgggtttg gataacgcat tgatccaatc attattgaaa taccctccaa
     7261 aaaaacttgt ttatatctcc tgtaatgttt ctacacttgc cagagatctg gttaatttaa
     7321 gtaaaaagtt caagattgaa tatttacagt ccgtcgacat gtttcctcag actgcacgtt
     7381 gtgaagttgt cgtgaagatg acgagactcg ctgactaaat gaaagaggtt gtgaaaaagt
     7441 ctgccctgta tcaagtaata agaacagcca aacaaaaata gctcttcatg ttttatgaat
     7501 actgtacttg tgaccgaaga gttaacagga ggacactatt tatttaaaaa aagggttgtg
     7561 acatagtttt tgtcacagcc ctttttgatt attattggat attcacgtct atcacttgat
     7621 aaaatgcatt tgtcgtatcg ctgatattcc atactgctaa aatcacatta tatccttttc
     7681 gatcctgcgg aagtgtgatc gtttggttga ctgtttttgg tggaacagtt gctttgtcgt
     7741 ctatttttgt gatcaattca aaatcactaa atttcaaagg ttgattagga ttccaagttg
     7801 gtttggtaat gtagtaatcc caagtacttg tccgatgttg tgctgttaaa ttccaagtaa
     7861 tatttaatgt tcctggatta accatgtttt tatgccatct gttagatgtc tgttcatcta
     7921 aaggctcaaa gccgctgact cctgcactag caatttttcc atcaatgaat gtatttttgg
     7981 tagcttcgat actttgcggt tcccattgtg ctcttccgac attttgattt aagtttcctg
     8041 ctgctgatgt tcctaggtat gcacggcttc ctggagaagt aatataacca tgcgcaaaac
     8101 ctggaatgct aaaaccgaac aaccctaaac taactaaccc aataaacaat aacgtactaa
     8161 tctttttcat gtagaaacct ccttcatttg ataaccacat tgtaaacgct ttattgtatt
     8221 aacacaaaca ttatgctttt ataattttat gttgaagtaa aaaaggtgaa aaaagtaaga
     8281 tgcagattat aacagaagta gacgagaaaa gtacaaatag aaaacatgag aatcaaatca
     8341 tatgatcttt ttcaaaaaca tcattcatat aaacaaatgt tcaacttttt aataacaaca
     8401 attatcaatt tttttcttac ttcacaaact aaatacaggt cttgctgtga gccttcatgg
     8461 taaactaata ttatagaaag gagttagtaa aatgaagatg ataaaagata ttcgtttttg
     8521 ggtttgtgtt ataggaattg tcatattagg ctttttatca gggttgctta gcggaaatcc
     8581 cggaaaatat tactattctt tgcaacttcc accatttgca ccacctagct ggatatttgg
     8641 gccgatgtgg accttactgt atatattgat gggtatttct ctttatttgt tacttaatca
     8701 caacaacaaa aaacagcgaa acaatcttgt cggtcttttt gtgattcagt tcatttttaa
     8761 ttttatatgg tctgctctat tttttaattt aagaaatatt ttcattgcag caatcgatat
     8821 tacactttta gttattttct tgtcagtgct tatgtatcag ttgtggctgc atcatcgcct
     8881 ggcaatgtgg ctcatgattc cttattattt atgggtacta ttcgcaactc tattgaatta
     8941 ttcaatttat tttttaaact aagcgctaaa aagagacgtc ctgtaattta acacatagaa
     9001 aaagtgccac ctaagttaga ttttttgtct aatttaggtg gcactcttta ttaaccaaac
     9061 tatttttttc tagtacccac ttgttgttcc atactcatta ttctggtcat aaccataacc
     9121 attttgttcc tgtccagcgt aaggatcata actttgagta tcttgacttg gtgtatagta
     9181 ctgacttgta tcttctgttt gctgataata ggtattcgga tcttggtact gatcatatgt
     9241 gttttctgaa taggaagaat aatcggtgta cccttcacta ttcgatccat caccgtttgt
     9301 cgaatcgcca tcttccgaat catcaaagaa catcattgaa gcattctcat ttttcaaatt
     9361 aggtaatgta tcgcttgttt ttatatttaa ttgtttcttc agttcatttt ggatcgaaag
     9421 aagatcattt tttcctaaaa tttgatagta gatatcattg atcatttgtc cttcgccttg
     9481 caactggtct tgtttgattg tttcaaacgc cggggtgtag ttcgtcgcta catcaagcat
     9541 gtcatcccaa tctaagtccg tcgtcacatt gttctcaact gcttttaaaa tttttctata
     9601 attgcttacg ccatctaaac ttaaaacttt attgacgatt ttcgtcacta cttcccgctg
     9661 acgacgttgt cgaccgatat cgccttctgg atcttcgtgt cgcattcgag aataggctaa
     9721 acctttttct ccattcaatg tttgttcacc tactggtaca tggacaccat ccaaagtaaa
     9781 gtcaatttta ttattcactt tgatgccacc gaccgcattg atcaaatctt ccatgccatc
     9841 caaattgatc gttacataat gatcaatagg aatatcgagc agttgctcaa ttgaatccat
     9901 ggccatttcg acaccaccaa atgcgtaggc atgatttaat ttatctaccg ttccataacc
     9961 tacgatattc gtataaatat ctcggtccaa actgatgatc gttgattttt tttgtttcgg
    10021 attaactgtt actaccatca tcgtatcaga acgtccttgt tccgttcttc ctaatccacc
    10081 ggtatctaaa cctaatagca aaaccgaaaa aggttctttg tcatcaatgc ttactctctc
    10141 agaacgtttg gaggatattc gattagagtt tttagaaatt ttgtttactg tttggctcgc
    10201 ttctcccata aatctgattc cgtatgctga taatccggca atcagcaaaa cgaatacccc
    10261 taacaaggtt aatagaactt tttgccatcg cttcataata cacctctgtt tcacattttc
    10321 taaaatattg tctcatataa ctgttcaatc agcaaattca ctttttaatc ataagaaaac
    10381 tttaaaaaac atttttgtgt aacgattatt attttttaaa atttctcaaa attcttaact
    10441 atcataccat accgtgaaaa agatcgaaag accgaataca cgcagttcgc aatcgtttta
    10501 tcttttttta tgtatttttt ccagaaaaag cgaacaacaa ggtattttcc aaataatcgt
    10561 gcagtaaaat gatcgcacat acctttccca tctttttaac agtctttgcc taccgttcag
    10621 attatcattc gatttcacga caatttcttc ctatgactgg tccttttgtt aaacccatct
    10681 tctattcgtt ttatttccag ctcactgcat ggctcttaaa atgactcgaa ctagtgattg
    10741 cattaccatc atcttttaat ggatagatat gctcctcttc aaagtaaaac gattttcttt
    10801 taaagtaata gaattgacat ggtaatgagt atgtatacta gtggtttcac aaatggtctt
    10861 ttattcaaca tccaaaaact gaaatttctt taaaatccat tactaacgaa gaaaatgttc
    10921 cttgcttgat aattagttag gacatgtcaa gtgaacaaat gcatttactt agccaaaaa
//
LOCUS       DAFEEZ010000083        10831 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000083
VERSION     DAFEEZ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10831
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.086"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            91..309
                     /locus_tag="LP245_002505"
     CDS             91..309
                     /locus_tag="LP245_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520380.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(598..1110)
                     /locus_tag="LP245_002506"
     CDS             complement(598..1110)
                     /locus_tag="LP245_002506"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBL1520381.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(1124..3421)
                     /gene="recJ"
                     /locus_tag="LP245_002507"
     CDS             complement(1124..3421)
                     /gene="recJ"
                     /locus_tag="LP245_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBL1520382.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(3563..4006)
                     /locus_tag="LP245_002508"
     CDS             complement(3563..4006)
                     /locus_tag="LP245_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBL1520383.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(4007..4795)
                     /locus_tag="LP245_002509"
     CDS             complement(4007..4795)
                     /locus_tag="LP245_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1520384.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(4792..5733)
                     /locus_tag="LP245_002510"
     CDS             complement(4792..5733)
                     /locus_tag="LP245_002510"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBL1520385.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(5910..6497)
                     /locus_tag="LP245_002511"
     CDS             complement(5910..6497)
                     /locus_tag="LP245_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBL1520386.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(6718..8025)
                     /gene="obgE"
                     /locus_tag="LP245_002512"
     CDS             complement(6718..8025)
                     /gene="obgE"
                     /locus_tag="LP245_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBL1520387.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            8319..9329
                     /gene="gap"
                     /locus_tag="LP245_002513"
     CDS             8319..9329
                     /gene="gap"
                     /locus_tag="LP245_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBL1520388.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(9414..10349)
                     /locus_tag="LP245_002514"
     CDS             complement(9414..10349)
                     /locus_tag="LP245_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL1520389.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            10535..>10831
                     /locus_tag="LP245_002515"
     CDS             10535..>10831
                     /locus_tag="LP245_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1520390.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKER"
BASE COUNT         3046 a         2420 c         1883 g         3482 t
ORIGIN      
        1 ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata tacgaacaat
       61 tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct tggcttagta
      121 ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc agctttactt
      181 gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa gtaccgtcaa
      241 tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta cagatccagg
      301 caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa cttttacggg
      361 ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta aagccagttt
      421 ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg gtctttgctt
      481 gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct gacttttgag
      541 ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt tttctgctta
      601 atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat ggagatccat
      661 caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga tcagttcgat
      721 cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca cacgttgacc
      781 tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta atccataagt
      841 cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa aaccgactcc
      901 taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc caactaccat
      961 atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc gataagcgtc
     1021 accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg gatagtcggg
     1081 aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt gttaaccatt
     1141 tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt ttattgagcc
     1201 gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg actttttgta
     1261 aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc ataaaaatta
     1321 ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga cgtatatcaa
     1381 ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt gtgcctaccc
     1441 cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg aatgaataag
     1501 accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca actagagagt
     1561 ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa acaatcgcag
     1621 cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct aaataaaggc
     1681 taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca aatacttgca
     1741 gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg ttccattcat
     1801 tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct tcttgagtac
     1861 caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca aatttcagat
     1921 gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga aataaaaact
     1981 gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca attcgctcta
     2041 ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct ctcatcaagt
     2101 caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg acattttcac
     2161 ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat aaatctcgca
     2221 tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat cctttagctg
     2281 atccatcttc ttttaaagta aggacaagcg ttggtttacc cgtttcattc attattttcc
     2341 cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga tggatatgat
     2401 tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt gcttttcttt
     2461 cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca tcaaacgtcg
     2521 caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt agtctgggag
     2581 caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg ctttcttcaa
     2641 atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct aatgaaacaa
     2701 ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc gctactaaat
     2761 ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat gctactccga
     2821 ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga acaatcgcat
     2881 aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg tctacaccag
     2941 cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca gtgatgatca
     3001 actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca tacccatgct
     3061 caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt gtttctttca
     3121 ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg attttttctc
     3181 cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt atcagatacg
     3241 gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt tcctcatggt
     3301 aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca cggatcattt
     3361 ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt gcttgtctca
     3421 ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa agcagaaaga
     3481 aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga tcttttgtac
     3541 gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg ggcgattgag
     3601 ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct tgtaactccg
     3661 cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc tgttcttctt
     3721 ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc tgagtcagct
     3781 gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat acaatcagtg
     3841 caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag gaagtgaagc
     3901 caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata atcaaaacta
     3961 aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac tttttgttaa
     4021 aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat tttgatgcaa
     4081 cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg cggacgatca
     4141 tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa tagcttccgc
     4201 ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact gtcgtaacag
     4261 ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg actgcaaatt
     4321 tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata gaggcgatat
     4381 taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt gtcaaaacca
     4441 tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg aatgtaagga
     4501 agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc ccgacttctt
     4561 ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct accttgaaag
     4621 cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct acaaatgcca
     4681 ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa cagatttgtg
     4741 cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa ttcatgcctc
     4801 ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg tcgtgttttc
     4861 aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat atctcgcact
     4921 gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag cagcttgatg
     4981 agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa atgtgctttc
     5041 atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt ttctcgtatc
     5101 gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt ttccattgat
     5161 cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt acagtggtcc
     5221 agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat gatcatgttc
     5281 aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat aaacagaaaa
     5341 ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca gcggataact
     5401 taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc cttttggccc
     5461 gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga gcccgggaag
     5521 tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt ttctcggacg
     5581 aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca accaaacttc
     5641 attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt ttgcaggaac
     5701 acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct ttaagttcct
     5761 ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg ggttcaaatt
     5821 aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa acagcagcga
     5881 acccgtttga gatcctctgc tgttttttat taatttgaag atccagaact ttcattgtcg
     5941 ttggaagttt gcggatgttt gtccttccaa gtcttttgtg cagcttcttt cgcatgattt
     6001 tcagcttctt tcgcatcatg cacatctttt tcgacatctt cataatccaa gcgagtaatt
     6061 tctccgccta attccatcat taccaattga ttcagtgggc gattgtcctc ttcatcagca
     6121 atcaagatca gtcctgtagc tccttcaccg attttatttc ctacaaagtc gaacacggtc
     6181 tgggcatctt ttatttcttt ggcatcttgt gtcgcaccga tcattcctcc ggcaaaccat
     6241 cctaataaaa tccctagcgg accacctaat acaccaacca acattccgat taatccaccc
     6301 gtagaagatt tgttattacc ggtaaagtcg ataaaatctt ctattttgaa ttgatgtgtc
     6361 ccattaggat catggctgac aactgccatc tgttctcctt taatcgaacg aacagcatgt
     6421 aactttttga tttctgaaaa tgcctgatat gcctggcttt ctacttgaaa atttaaaatg
     6481 attactcgtt tgctcattaa aaacgcccct ttcatacctt cttgttattt attttacctt
     6541 taattgaaaa ataagaaaag aaaagcactc tttttttcca ataaaatagg gctgtgacaa
     6601 aagtcgtatc acagctcctt tttccgaata aacggcgttc ttgaagctga tcacttctgt
     6661 cacaacctcc cttaaatctg aatctatatt ttttggtatt tgtttttatt tgcttgccta
     6721 ttcgacaaat tcaaattcaa actcaccgat acgtacaagg tcgccatctt tcgcaccgcg
     6781 tgcccgaaga gcttcatcca cacccatacc acgtaattga cgagcaaaac gcatcactgt
     6841 ttcatcatga tcgaaattcg tcatttggaa taatttttcg atcttctcac cagataagat
     6901 ccacgttgca tctgaatcac gatcgatttg gaactcagga ccttctggat tgaatccata
     6961 gtgtacagtt tcttcttcca gttcttcttc gtacaatggg aattctggcg ttacttctaa
     7021 caaatctgct gtagcattca ataacgcgtc caatccttgt cgagtcactc cagaaattgg
     7081 aaatactggg atgtcatcag caaattcatc ttctttttcc ttgttcagct gttctttgaa
     7141 tttcactaga ttttccggtg catccggcat atccattttg tttgccacga tgatttgcgg
     7201 acgctctagc aagcgtaagt tataagtaga taattctttg ttgatggcaa gatagtcttc
     7261 ataaggatct cgtccttcca tcccactcat atcgatcaca tgtaaaatta ctcgtgttct
     7321 ttcgatatga cgaaggaatt gtgtacccag cccaacacct tgcgaagctc cttcaatcaa
     7381 gcctggcaag tctgctgcgg caaaacttct gccatcactt gtagtaacca ttcctagatt
     7441 aggtacgagc gtcgtgaaat gataagcgcc gatttttgga cgagcagatg aaataacgga
     7501 tagtaaagtc gatttcccga cagatggaaa acctacaagt ccaacgtctg ccaatacttt
     7561 caattctagt tcgatttttc gctcttgtcc tggttcaccg ttttcagcaa tttccggtgc
     7621 aggattccga ggagaggcaa aacggatatt ccctcgtcca ccgcgtccac cttttgccac
     7681 aactagtgtt tgaccatttt caattaaatc tcctaaaaga gcaccagtct ccgcatctcg
     7741 gacagtggtt ccttgtggta ctttaacata ggtatcttct gaaccacgac cgtgcatccc
     7801 tttactcatc ccattttcac ctggctgcgc tttgaaatgg cgattgaacc gaaaatccat
     7861 caatgtacgt aacccttcat cgacgatcaa gatgacatcg ccgccacgac caccgtctcc
     7921 gccagccggt ccgccgtcag gaacgtattt ttcgcgacga aatgcaacca ttccgtctcc
     7981 gcccttgcca gctttcacat cgatcgttac ttgatctaaa aacatggaca taattaagtc
     8041 ctcctattat tcatttattt atttgactgc ctgaatttcc acaataaaca aaagtcttac
     8101 ttattttatc ggtgaaatct gattttgtct atcatttcag caaaaagatt gtttaccttc
     8161 ttcttttttt atcatttggt aaggtttcca accttttttc tgctaccaag tataattttt
     8221 tgacaaaata ttctttgcgt agcagaataa cagtgtatta attgtattaa ttgaggatgc
     8281 cgtttcacag cacccctaat aaaggaggaa cttttgatat gacagtaaaa gtaggtatta
     8341 acggatttgg gcgtattggc cgtctggctt tccgccgcat caaagaagtc tcagatgata
     8401 ttgaagtagt agcaatcaac gacttaacaa gtccaactat gttagcacaa ttattgcaat
     8461 ttgactctac tcatggtact tatcctggca cagttactgc aacagaagac tcaatcgtag
     8521 tggatggcga agcaactcgt gtttatgcag aacccgacgc aagcaaaatc ccttgggcaa
     8581 aagaaaacgg tgtagatatc gtactagaat gtactggttt ttatacatct gaagaaaaag
     8641 caaaagcgca tttagatgct ggtgtcaaac gagtagttat ttctgcccca gctggtgcta
     8701 tgaaaaccat cgtctataac gtcaatgatg atacattaga tgaaaacgac aaaatcatct
     8761 cagcaggttc atgtacaaca aactgtttag cacctatggc ttatttctta aataatgaat
     8821 ttgggatcga agttggtaca atgacaacag ttcatgccta cacttccaca caaatgctct
     8881 tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg ttcagctgct gacaatacta
     8941 tcccacattc tactggtgct gcgaaagcaa tcggcttagt tatccctgag ctacaaggaa
     9001 aattacaagg acacgcacaa cgtgttccag tcgttgatgg ttcattaact gaattggttt
     9061 cagtattgaa aacaaaagta actgctgatc aagtaaacga agcaatcaaa aaacacacag
     9121 ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt ttctagcgat gtcattggaa
     9181 caactcaagg ttcgatcttt gacccaacgc aaacagaagt aacaactgct ggtgatttcc
     9241 aacttgttaa aactgttgca tggtatgaca atgagtatgg atttacttgc caaatgattc
     9301 gcttactaga aaaattcgct aacttgtaat ttgatagatc aatcgataaa agaagccttt
     9361 gactggatcc agtcaaaggc ttctttcttt tcatccccta cttttaaact cgttcaatga
     9421 acatattggc ttaaaaattg ttggactact tgctgatatt tttcaggatc tgtcttgtat
     9481 gcttccgcat gctcggctcc ttttacaaca tacttttctt ttggtccctt cgttgcacga
     9541 tagaccttat ctaacatttc aaatggtaca aatgtatctt cgtctccatg tataaagagc
     9601 attgggcgct ggtttttctt caattgttcc actgcatttg cttcaccgaa aaagtagcca
     9661 gcacggactt ttgtcactag actcgttact tgcataagcg gaaatgctgg aagactaaac
     9721 atatcgtcta gctgataagc aagctcatca tgaacggaag aataaccgca atcttcaatg
     9781 attgctttca cattatctgg tagtttttct ccgctagtca tcataactgt tgctgctccc
     9841 atgctgacac cgtatagaac gatttcttgc gattttccat tgttttctag cactttgttt
     9901 atccactgta catagtcttt acgctctggc catccaaatc caatgtaatc cccttcgctt
     9961 tttccatgtc ctcttgcatc aggaacaagg acattgtaac ccatatcatg aaacatcttt
    10021 gcgtaattgg tcatcgtttc agcgtttccc atatagccat gagccacaag agctgttttt
    10081 tcacttttcg tttcagcagg aagataaatc gctgataatt tcagaccgtc ttttgaagtg
    10141 atggtccaat cgcttcggtt ttcttttgaa ctaaaccatt tatgtgcatc cgtttctttg
    10201 gatgtctgtg ttgtaccagg tgtatcttcg tctaaaaagt ctttctcaga aggcacaaca
    10261 gcataattat aaaaataatt ccctgcaaac actaacgcaa caatcagagc taaagcgacg
    10321 cctaaaagga ttttcatcca aagtttcata aatcatccat ctcatttctc ttttttcata
    10381 taaccttgaa ttagtataat caaagaatct ctactatgca atgttcattt ttataacccg
    10441 cgaattgtaa aattaagtta gaaaaataaa aaggcattta tggtacactc aaattgtatt
    10501 tccgacgaaa gaaaacaaag gagtgtaacc ataaatgacc tacaaacatc ttaccataga
    10561 cgaactgaca atgatagaat catattatct tcaacataat aagccggttg aaatcgctaa
    10621 ccgaatggga cgtgctatac aaactattta taatgtagtc aataagttca agcaaggcaa
    10681 gactgctctt gattattggc accagtataa agaaaataag aaaaaatgtg gtagaaaagt
    10741 cattcaatta cctgctcatg aagtagatta cattaaagag aaagtcactc ttggttggac
    10801 gcctgacgtc attatcgggc gaaaagaaag g
//
LOCUS       DAFEEZ010000084        10717 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000084
VERSION     DAFEEZ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.087"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(25..162)
                     /locus_tag="LP245_002516"
     CDS             complement(25..162)
                     /locus_tag="LP245_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBL1520391.1"
                     /translation="MKRGIVMEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKG
                     K"
     gene            complement(159..1343)
                     /locus_tag="LP245_002517"
     CDS             complement(159..1343)
                     /locus_tag="LP245_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBL1520392.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(1600..1854)
                     /locus_tag="LP245_002518"
     CDS             complement(1600..1854)
                     /locus_tag="LP245_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520393.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            complement(1879..3021)
                     /locus_tag="LP245_002519"
     CDS             complement(1879..3021)
                     /locus_tag="LP245_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBL1520394.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            complement(3081..4433)
                     /locus_tag="LP245_002520"
     CDS             complement(3081..4433)
                     /locus_tag="LP245_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL1520395.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFWVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            complement(4504..4848)
                     /locus_tag="LP245_002521"
     CDS             complement(4504..4848)
                     /locus_tag="LP245_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBL1520396.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            complement(4858..5232)
                     /locus_tag="LP245_002522"
     CDS             complement(4858..5232)
                     /locus_tag="LP245_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1520397.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            complement(5245..5559)
                     /locus_tag="LP245_002523"
     CDS             complement(5245..5559)
                     /locus_tag="LP245_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1520398.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(5673..8900)
                     /gene="fss3"
                     /locus_tag="LP245_002524"
     CDS             complement(5673..8900)
                     /gene="fss3"
                     /locus_tag="LP245_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBL1520399.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITDAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            complement(8979..9641)
                     /locus_tag="LP245_002525"
     CDS             complement(8979..9641)
                     /locus_tag="LP245_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520400.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            10258..10488
                     /locus_tag="LP245_002526"
     CDS             10258..10488
                     /locus_tag="LP245_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520401.1"
                     /translation="MMEDFIRKNISDEYADFYEQSSKKDKFQMDVSILAILAFSENNQ
                     PVIAKKETVLSEGKIKTRYILEVETKFKNRSE"
     gene            10494..>10717
                     /locus_tag="LP245_002527"
     CDS             10494..>10717
                     /locus_tag="LP245_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520402.1"
                     /translation="MLFNETQLWFKFDPSNRFIKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVP"
BASE COUNT         2954 a         2365 c         1821 g         3577 t
ORIGIN      
        1 aaattttgac cgaaattcat ttcatcactt tcctttcttt tccattgctc ggtccgccgc
       61 tgcacttgca tgcatcaagc acatcacagt aacaccaagc atactgccac caaacaccaa
      121 taaaatatct ttcacaattt ccatcacgat tcctcttttc atataatcaa attttcaatt
      181 gccatacttt gttgctccaa aatctttttg tgccggtctg atagtcgagt attatttacc
      241 atatcctgaa tgtacgttgt ctgattcaac cgatccaact ccttggccat cttccacgta
      301 ggggcgactt gtcgtccaag ccagttcaac gttcgttcaa tggtataagg cttcggttca
      361 gaagttaatt gaatttcctt ctgattccgt ccaatgaagc gcccccattg ttcattcaag
      421 ggccagttag ttcgcctttt gccttccacc ttatccgcaa atcgcaagta ccggttaata
      481 atggaaaatg tggtactttc aatactgcga ccttttaaca aatcttgaat tgcatgataa
      541 gctcgatcat ttttcagtcg gatttcaaaa cgatttttcg tttcggtctg gtctaaagga
      601 atccctaact tgatatattg ctcatagtct ttttcgtaca aacagaaata gacctcactc
      661 ttaagactgc caatatacaa agtattgccc ataccatctt tatcatcagg tttcaacagt
      721 tccccggaac gatagctttt gaaggtacga aacaaggaga tacattcttc cttctgacat
      781 tttttcgtta aatcaggaat atctaacagg ccaactcgat cattgattgc caggtctaag
      841 cgtttcatca cgccaccggc ttttagacaa tcttcgaaaa agtcatacca gctacgcttt
      901 tgggcgagta aaaaagtttc aaactgccga caaccacgac cctttaattc taaaaggacg
      961 cctttatctt cttcatgtga caacatcacc acaatatctc ccataacata ttgttcttga
     1021 taggagtaaa aggcgtaatc ttcgtggagc atataatcaa atttcaaatg gagaatctct
     1081 tgaatgattt tcctcgcatc cgttgtggga aagcgaatcc ttacatagtc aaacagtaac
     1141 gttaaaggta actcgggatt gaaactttcc agttggtcaa aaattttcct catggttttt
     1201 gtcgatgcgg ttacgccacc attttctatc tgatttaagt acgggcgact aagtccacaa
     1261 gtcgtagcta atttattttg tgaaacgcca tattcattac gccggtcttt taatagccga
     1321 taatctaaat tcctttgtgc caagttctca cctccaaatt taaggtgtta actttttcaa
     1381 atcagttaac atctacacaa attgcttatt atccttgata ggacagccat tccttatcgt
     1441 tgcttgctta ttttttgtgt ttttgtaccc ccctgttaga tacggggggg tgagacatca
     1501 tggccggcta acgccgtcca taaacaggca cagcaccacg gaggatttct gcttcgcaaa
     1561 tcccccgcgg tcagtgccta tcagtggttt atttggccgt tactccgcgg taataccctc
     1621 aatttccaac tctgctttta tctcaaacaa gtattggcgg atatcaggtt ctttagcaaa
     1681 gtccgcaatt cgttccaatt cactgatgac ttgattcagc tccattcgag catccgtttc
     1741 ctcatcaatt acatacggat catcagggac tttcaccccg tttttgcgaa tatcaaaatt
     1801 gagccggtac agttcttctt ccaattccgg atctgactga atcttgccaa tcacccagta
     1861 gattccccaa tcaactcatc ataaatcatc tgtttttacc tcctttaatc ttctagcaat
     1921 atcaaaaatg accggaactg ttacagaatt tccagcctgc ttatacaact gactatctga
     1981 attgacttga gaagctcgat caaaagccca gtccggaaag ccctgaagcc gccagcactc
     2041 cctaggtgtt aactttcgaa tttgatactg atccgtgacg actgcttgtt ggtctcctgt
     2101 taataaggta tgcacacttt gttttcccag acggcctcga cgacttgtgg aattaggaaa
     2161 agccaggttc acactgttcc ctggcttcac ctcttgatat tctgtttcgt ttttccgaag
     2221 catgatcttc gttccgcctt gtttcgttga caaagtaggc gctgttccag ttatctcata
     2281 aacccgattg ccttgttcaa aatttcccag taacataccc gctacagaaa ttccatcatc
     2341 taccggcaat gcgattttga ttccttcatc accggtcaag gtaggcgcta cgtcatctga
     2401 cccatagact tgtcccccca ttcctcgatt ggaagggttg atatttaata agtttctgat
     2461 gttttgatca gatgttggag acgatccaat gataggaaat acttgttcgg tacatgcgtc
     2521 tcgagaatgt ccgataagga agatccgctc acggttttgg ggaacgtagg cctttgagtt
     2581 aagcacttgc cattccacat cataccccaa tccatccagc gttcggagga tcgtctcgaa
     2641 cgtagcccct ccttcgtgat tgagtaatcc ccggacgttc tcaaggaata aaaacttagg
     2701 ttggagaata gcggcgaacc gagcgatttc aaagaataaa gtacctcgag tatcggaaaa
     2761 tccttgccgc tttcccgcaa ttgaaaaagc ttggcacgga aatccaccgc aaaggatatc
     2821 cactggtccg agagattgaa taaactcgtc tgatacactt gtgatgtcat gcatttccac
     2881 ctccttactt gtatcatgga ttgccttata actctggcga gcaaaatcat caatttcaca
     2941 aaagccgata cactggtgac ccgcttgttc catacctaag caaaagccac caatcccagc
     3001 gaataaatct aaaaatgtca taaatcacct cgtaaaaaaa gcccaggatt cttgacactc
     3061 ctaggctaca tactattatt ttatccttcc gtattaacgt ttaatccacc aatgtcgcta
     3121 atttccctta agaaatcata tccttttggt acaagtggcg tataaaactc actaatcaca
     3181 ctccctcccg tatctacata gcctcgacct ttgatacgct tcataaagaa ttttttatca
     3241 acctcgccaa acatcatgga atatcccagt tcactcatac gacccaaagc cacccagaaa
     3301 ttaaattgat cgcgaatccc gtctcctaaa tatttcgcat ccggtctttg acaagctaga
     3361 atcagaaaga aaccagattg acgacctaac atcacgattt gtttgagctt attcaaaatc
     3421 accgcacttt ccttcgtcgt taacatttcc atataaacca cgtattcatc aaagattaaa
     3481 aagtttggtg gaagtccaag aaacgcataa ttctctcctg ttttgtagtt gggcatttct
     3541 ttcattgcct tgctacgagt catcatgcgc tcatagaaat cttccacaca agcagaaatt
     3601 tcctcctttt gggaatagac atgaggcatt accgtaccta aatcggctaa gtccgcattt
     3661 ttgggatcaa gaacaaaaag ctcggcatca gattttaata aagcctcgat gatagtgagt
     3721 aaaaagtaag tcttcccacc acctgtgccg ccagcgatta acatatgagg taaagaatca
     3781 taagcccata cttgattttt catcaatcgc aaagccccac tttctgccac tacttcgtct
     3841 atcccaattc gattggcaat tatatcatac agtaaagtgt actccacata ggagtctttg
     3901 agttcctttt ctactagttc acaatataga ccactttcta acttcttttc cagctttaaa
     3961 agctgatctt gatattttcc cagtgaaatt tgaacgcgaa tagaaagtaa accatccttc
     4021 atacggtaat agattttggg gaagtaactg attgtctctt tggttcgact actattgagg
     4081 tctttgaaaa atccttcact ctgagtttgt tttacttcgt accaatgatt ttctagaatc
     4141 atccgggcta gcttttgtcg atgccacaaa ctgcgccaat gatcctgaaa aaagtgtata
     4201 taaagcaaca tcgtgcttcc tgaaagaacg agacttccta gcaaatagat taaatctttt
     4261 atagaacgaa cgatttctat agtagaaagt gatagcttag aaatatcaaa ttgtctaagc
     4321 tcttgaaaat aaaagacgct catccaaccg atgaacagag cgagtagcca gccaagaaca
     4381 aagtgataaa ccaagtgctg atctcctgcc cgtatacgat gccctttgta catttttatg
     4441 gtttccacct ccaatcgaaa aaagcttcat aggatttcat tgatccaatt tcaagcagtt
     4501 atgctagtca tttactgcta tagggagttg tttcgtttcc actagttgct ttaaaaaaac
     4561 ttcaatggca tccggcattt ccacaccaat ttcttccaat acggtttcgg cttctcgaca
     4621 tagactttca tttacttcga taaccataaa gaaggactct tcttccccta accaattcag
     4681 tacatcaaaa tcttcttcgg catcgttacc tacttccagt aacccttgat gcataatcag
     4741 aaacattttt tcatcatagg ttaatgcttt agtgagttgt tcctccgtta gctcaccttt
     4801 tccatattga tcgagacaat ctaaaatatg ttcaacatta atttccatac gcttcaccta
     4861 tttctttcct tcattttggt ttgtagaatt tccctgatct ggttgtcgtt tcaagactaa
     4921 atcatcggcc ttaatgaacc aattgacagt agttccttct cggaaaacat aattggcgac
     4981 cgtatccatg attggattga ccaactctac ctctgcgtca taggcaaact cgcgtaaggg
     5041 tacatttgct gggatactaa cttggatcat tcgaccttgc gcagaggatt tcaaattata
     5101 agtccgttct tttacctcgt tactaaccgt tccatcctca ttttgcttcc gtacttctcg
     5161 gcgtaatgcg gaaaatcgta atttcccaaa cgttagtcct gaatctacaa caataccttc
     5221 tgttaatctc atcttctttt cctcctatgc tttcactaaa tcatcgacat acaacacgta
     5281 gtcggtaaac ccacgattct caatctcata gcctttggca accaaatggg gattcacggc
     5341 ttttagtggt tgatcttgat caaaatcctt ttcgccggct tccgcagcta ccaccacttc
     5401 aatatcatcg gctcgttgct tactggaata caaatgataa ctacgaccaa ttactgtagt
     5461 attccgccca tatccttcag ttaaaacttc gccttcgccg gcatacctta tctttccaaa
     5521 ggtttcggcc atatctggca caacaaattt caattccatc ttcttttcct cttttcattt
     5581 ttagttttgg atacaaaaat agcgcgacca ctttttttag gaggcggtcg cgcacgttgg
     5641 tttttcctat ttagttgttt catcacatca ccttagtttc ggcgattcca gaaataatac
     5701 ccagcagtcg caaagatcaa ggtaaaccca ataaacagca gaacattaga atttttctcc
     5761 cctgtttgtg ggaatgtctt tactgtagga ctagattctt gagagtcact tggaacagtt
     5821 ggtatttccg gttgttctgg tgcacttggt gttgtcggaa cttttttagg tgttaaagtt
     5881 tgagtttttt cttttagatc ctcattgtgt ttcccattga tgtttccgtc tttgccatag
     5941 ttaatttctt tgaaggtaaa acttgtacct tctggatatt tacttgtgtc cactttttcc
     6001 gcaagtacgg ttttagtgaa ttctttgtca ttcacttcat aatcaatttt gccagatttc
     6061 caaatttctt tggtcgtatt atccggaagt aatgcataca gaattgtttc aaaagcttct
     6121 tttgagccat ccagtacatc atgggtaatc gacacatcat cgaacatatc caccacatcc
     6181 ccatgagtaa aggtttgcga accatcttct aggtgggctt ttgtttggat ggaaacatgg
     6241 cgttccaccg tacaattgac agtttgggct tgattgttca agctagcatc tttcgctact
     6301 ggatcatcac ctgcttcata gggtttcttg ttttcataca catagttgaa taagacgatg
     6361 gttttatcca aaacttgttc tgcggttaat ttatgcaaaa ttttccaagt tcctgttttc
     6421 tctttattcg ccaacgttgc ggttgtttcg gcaattacca ctggtttggc tttttcatct
     6481 ttttcttggg cagcttttgt cgcttccaca tcaatggctt gcgctaccac ataccagtct
     6541 tctttgattt catgcaagtt atagctcaat ttatcaacta gctcggtaga atcaaggtct
     6601 gtcaattctt tgcctccgtc tttccaagtc ccaagagaag ttaagctatc ttcttcttca
     6661 ggtaaatcat agagcatcaa acgattcaag ctaacagaaa atgctttatt cgtcagtttc
     6721 tcgtaaggaa cggtcaccgt tttaattggt tgtttttgtc ctttttcggt aatcgtaaaa
     6781 atgtattcac tcttagtgta atccgcttta ttttctttaa aagtagaacg gatttctaat
     6841 ggcgtaattt tttgaaatcc ttctggagcc tctacttctt caagtaaata atccccataa
     6901 ggaagatttt caaacttgcc atagccatca aaacctagtt gctcgttata agctgtaatt
     6961 gcttcatctt cggcatctgt aatctcactg gttccttcca atggcgatac tttaaaggtc
     7021 agatcattga agccagtttc ggcagtccca gcagctgatc cagcaaattt aaagaaatca
     7081 aagccaaagc gaatgacttg ttcttttgcc gtaacatctc gggtaatcac ggcatttttt
     7141 tcgttatcat ccaccttttt gatggaaaca gggtactttg tttcatccaa ggtatatcct
     7201 tcaggtgctt tggtttcttg ccagtaatac tcattaatcg ctaagtgttt aacagcaact
     7261 tgattctttt catctaaagt caaagtcacc gtttcatcag aagctttcgt tcccttcact
     7321 aactctggtt taaaagcctc actccatttg accgcttgac catcttttgc agtaaagaga
     7381 gtatattcag ctcctttaaa ctcagcttta ccttgagttt cattaccggt atctttgtct
     7441 tcttttgtca aagtggtttc accagtgatt tcttggtttt gcccttttac gttactggta
     7501 acaagagcca cggtttgatt gacatagttc aattcgactt ttactggttt aaaggtattc
     7561 acaaagccat tactagcttt ggtttcggtc acataatagg ttcccaattc caacgcattg
     7621 gcaatctctt ttggtgtttc cgcatgacct ttttcatccg tggtcatttc ttggacaatt
     7681 tcaccggttg gactgtcttt gcgaatggca aacgtatttc cggctaatga gtatttgtcg
     7741 ttccaaagat cagttcctgt ttccaccccc attttattca aaatgatttg acctttttcg
     7801 cgagtatttt ttgaagtcac agaaatagtc tcaccagatt taatggttgc ggtgattggt
     7861 gtagtgtcaa tcgtataagg agctggcact gatttttcag taatggttac tttcgcgcca
     7921 tgaggaatct catccaatgt cgcaatgcct tctttatcgg tggtcacgtc ttttgcaggt
     7981 aatgtttttc caaagtctaa atggaaaacg gttcccggta caacatttcc tgtttcttta
     8041 tcgacttttt taatcttcaa agaaccctca gtttccacat caattttgat tgtgtaggta
     8101 ttgggcttat caattgcccc cgccatcaaa gtttgttgac cagccatttt ataagctacc
     8161 ggtgttcctg tattagctga cttctttagg gttaattcac cactctcttt tgaattggca
     8221 tttggagtaa tcactagttg attgccgttc acacgataat caatatttgc gatattctcg
     8281 acaacttcat caaactccga taaattcaag ccgttcgtat ctgtcacagt agtcgattga
     8341 cctaacacgg ttttcactgt ggagttatgg aagcttggtt tcttttgata atccgcaatg
     8401 gcttgattga tttttgactc aatggctgcg atatttactg cactaccatc agaacgttta
     8461 attgagtgaa gcgtgtagcc attaacttct tgccaaatca tcttctgggc cacaatatgt
     8521 gtatccacat ccgtaccagc ttccttccat aaaacggaaa ctaatttcgc tttctccgac
     8581 atatcaggca atggattttt ctcataacca ggagtgaact cattgtaaat cggcacccct
     8641 ggctcaatac agaaaatatc ttgcttcaca ccattgtaaa ctgcatagtg cggaacggta
     8701 acttctgaca tgggacgacc atcgctaaat gtaccttcga cagcatactg gtgagccaaa
     8761 tccaattcca cagttaccgt ttgtggatga gtaatttcat cagcaaaggc aatcgttggg
     8821 ccaagcgatc caccaattgt ttggcataat agactcagtg ttgcgagcaa acgccaattc
     8881 ttaaatcttg gctttttcat aaaataaatc tcctttcgtt tttgggtaat aaaaaagacg
     8941 tccaaatttt aattttgaac gtctgattta gagtgatact atttagtttt ctttgtcttg
     9001 gataggttgt ttctctgctt ataaattttg attcttcgat aatcaaatcc aatctctgcc
     9061 atcaattcct cccaattttt gttcgttctt ttcataattg tatcaactga tggtagtttt
     9121 ggggattgaa ctagttttcg aaactttgtc attgataaat catcctgtag ttttaatcgg
     9181 attatttcat tttttagttc taacagcagt tcgaaatcag taaatcgaga tccatcattt
     9241 ttttctttaa aaagtggacg tatatctcct aacatctttt taatggtact aagtgaagga
     9301 atattcttcc ctactgattt ttgttcgtac attcgttgag aggttatctt ctcgcactta
     9361 ataaaggctt ctactatttc caataattct tgttctgaca ttctagccca ttttccatac
     9421 ccagtatttt ctcgtcctat actaatcaat aaattctccc atgatccata ttttttgtta
     9481 atgaaccaca tacttggtgc agaatttgga ttttctgata gctttttctg gtattgacgg
     9541 ctagatgtaa ttccgtgttt ttcgatgaat tcattaattg ttaaaatcag ttttaactca
     9601 ctttgatttt tccaaatgat acgtccatca ttttgcttca cgataaaaac tcctaatagt
     9661 tatttagata gaagcctatc acatcaactt tttagtagaa aagtacatgt tttgtctttt
     9721 ttgctaatag ctgacccttt gagaaacttg ggttcaaaag ttgctaaatt cggtaaatgt
     9781 tttggtattt ttcgtattat atttgtcgtc aagctgacta ctaaattttg ccctattttg
     9841 acgacactga tagtcaatgt cggacaatct aggacaattt ttaagggaat atgattgaaa
     9901 aatggtccaa aacagccaaa aatggcttaa aactgtgata gagaaaaaag aaaaagccct
     9961 tgatatacaa ggacttttca caaatttcag atttccaagg aagttttccg tgtttatctt
    10021 ctgatttctt tgatacgagc agcttttccg tgtaatgcac gtaaacaaaa ccactatatt
    10081 ctattatgta tctaataccc tcaaaacagc tataaatcaa caataccgac atataataaa
    10141 cactatgttc aatctgagat atatcaaagg taaacgtatt tttgccccct ttttgcccct
    10201 caaatatcgc tttacaacga gaacgtaagt tcgtataatc gttttgaggt gatttttatg
    10261 atggaagact ttattagaaa aaatatcagt gatgaatatg cagactttta tgagcaaagc
    10321 agcaaaaaag ataaattcca gatggatgtt tcaatcttag ctatattagc tttttccgaa
    10381 aataaccaac ctgtaattgc gaaaaaagaa acagtattat ctgaaggcaa aataaaaact
    10441 cgatatatat tagaggtaga aactaagttt aaaaatagat cggagtaatg gctatgcttt
    10501 ttaatgagac gcaattatgg tttaaatttg atccttcgaa tagatttatc aaagattttt
    10561 ataaagtatg ggattcagaa gttttctttt tagcaatcga agatagttta ttaatcaatc
    10621 tctactattc taataagaac tatttcaaaa ttcctgctgc gaaaactaga atgaagaagg
    10681 atgtatattt tttgtttgat atcgtgactg acgtgcc
//
LOCUS       DAFEEZ010000085        10264 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000085
VERSION     DAFEEZ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.088"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..1014
                     /locus_tag="LP245_002528"
     CDS             <1..1014
                     /locus_tag="LP245_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBL1520403.1"
                     /translation="ELKPKHERQNFLVRDDRLDHAVAFLWKDPQTNETVGASYQGTFI
                     DYERFGERGTYKHIDKNSTANHGFNLKIGDPKQLKFFESSIDLLSYAALNRDQLNDTW
                     LVSMEGLKHHVISHYFGEAVSELRKKQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDP
                     FTNQKVRCERGIANDWQVPKEYKVIYEEVAKEEKITPEAIMAIHKTENNLQLTNQLVS
                     AHKVNASFGQQLSVNDSIEAINLKDICREVAKELKACERVDGTYDFDRFYQEKGDINA
                     QILFSYKAEQYYKGYKNHEHEFVPEVKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQ
                     ERE"
     gene            1025..3229
                     /locus_tag="LP245_002529"
     CDS             1025..3229
                     /locus_tag="LP245_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBL1520404.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEATRHLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNGRTSQSVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            3245..3394
                     /locus_tag="LP245_002530"
     CDS             3245..3394
                     /locus_tag="LP245_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520405.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            3470..4063
                     /locus_tag="LP245_002531"
     CDS             3470..4063
                     /locus_tag="LP245_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBL1520406.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            4076..4975
                     /locus_tag="LP245_002532"
     CDS             4076..4975
                     /locus_tag="LP245_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBL1520407.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            4978..5451
                     /gene="ssb"
                     /locus_tag="LP245_002533"
     CDS             4978..5451
                     /gene="ssb"
                     /locus_tag="LP245_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1520408.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFANQNGNR
                     EADFINCVIWRKPAETMATLAKKGGLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSTTSPSPTTFEQRDTNNGLDASQNPFGGQSIDISDDDLPF"
     gene            5817..6077
                     /locus_tag="LP245_002534"
     CDS             5817..6077
                     /locus_tag="LP245_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520409.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDQFTRLMGI"
     gene            6522..6728
                     /locus_tag="LP245_002535"
     CDS             6522..6728
                     /locus_tag="LP245_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBL1520410.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            6728..6979
                     /locus_tag="LP245_002536"
     CDS             6728..6979
                     /locus_tag="LP245_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520411.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTTETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTELEN"
     gene            6995..7411
                     /locus_tag="LP245_002537"
     CDS             6995..7411
                     /locus_tag="LP245_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520412.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGACYIMK"
     gene            7393..7665
                     /locus_tag="LP245_002538"
     CDS             7393..7665
                     /locus_tag="LP245_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520413.1"
                     /translation="MLHHEVIRRIQKDFSCMEEMKYFVQNVEEQLYLESETSQTKVTV
                     SHNRLDVYKRRPESLKKGAELLRLETEKYVMNVYLEKSELVENFMD"
     gene            7832..8233
                     /gene="tnpA"
                     /locus_tag="LP245_002539"
     CDS             7832..8233
                     /gene="tnpA"
                     /locus_tag="LP245_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_045009167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBL1520414.1"
                     /translation="MSEIHYGRGYVYSIQYHLVWCVKYRHDVLYGQVDIDVKQFLKQI
                     ADDNNIKIIEIESDKDHIHLLIECTPQHYIPSIVKVFKGASARLLFKKHPELKQLLWG
                     GHLWNPSYFVATVSENTEEQIRKYIQNQKKK"
     gene            8245..9390
                     /locus_tag="LP245_002540"
     CDS             8245..9390
                     /locus_tag="LP245_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1520415.1"
                     /translation="MLQHRAYKFRIYPNQEQEILMTKTIGCSRFVYNYFLNLWNHEYT
                     TTGKGLSYNSCSAMLPQMKRNAETIWLKEVDSIAIQSSLKNLSDAFSRFFKKQNKRPQ
                     FKSKKHPIQSYTTKNVNNSIEIRNNFVKLPKLGFVKFAKSQEPKGRILNATIRKNSSG
                     KFFVSILCEEEIVEFPKSNSAIGIDLGITDFAILSDGQKIDNNKFTSKMAKKLKREQR
                     KLSKRALLAKKKGVNLFEAKNYQKQKRKVARLHEKVMNQRNDFLNKLSTEIIKNHDII
                     CIEDLNTKGMLRNHKLAKSISDVSWSSFVTKLQYKANWYGRKIIKVDKWFPSSQICSN
                     CGHKDGKKSLEIREWTCPVCHAHHDRDINASINILTEGLRLHVMGLA"
     gene            9628..9891
                     /locus_tag="LP245_002541"
     CDS             9628..9891
                     /locus_tag="LP245_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBL1520416.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            9885..10235
                     /locus_tag="LP245_002542"
     CDS             9885..10235
                     /locus_tag="LP245_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL1520417.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
BASE COUNT         3833 a         1677 c         2041 g         2713 t
ORIGIN      
        1 gaactaaagc caaaacatga acggcaaaat ttcttagttc gagacgatcg tttagatcat
       61 gcggtcgcct ttttatggaa agatccacag acaaatgaga cagtaggggc gagttatcaa
      121 ggaacgttca ttgattatga acgttttggt gagagaggca catataagca tatagataaa
      181 aattcgacag cgaatcatgg ctttaaccta aagatcggtg accctaagca gttaaaattt
      241 tttgagagta gtattgattt acttagctat gctgcactaa atcgtgatca gttaaacgat
      301 acgtggttag tttcgatgga agggttaaaa caccatgtga tcagtcatta ttttggtgag
      361 gcagtatctg aattgagaaa gaaacaagcc tttcctcaat ccatcgagat ttgtgtggat
      421 aatgaccgtg caggacatat tttctacgaa aaagaacaat taatgggcgc agttgatcca
      481 tttacgaatc agaaagtacg ttgtgaacga ggaatcgcta atgattggca agtgccaaaa
      541 gaatacaaag tcatttatga agaagtcgca aaagaagaaa agatcacacc agaagctatt
      601 atggccatac acaagacaga aaacaatctg caattaacga accaattggt ttccgctcac
      661 aaagtaaatg cgtcttttgg tcagcagctt tctgttaacg attcaataga agctattaat
      721 ttgaaagata tttgtagaga agtcgcaaaa gaattaaaag cttgtgaacg cgtggatggt
      781 acgtacgatt ttgatcgttt ttatcaagaa aaaggggata ttaatgctca gattcttttc
      841 tcttataaag cagaacaata ctacaaaggc tataaaaatc atgaacatga atttgtacct
      901 gaagtaaaaa aggattggaa tgatcaattg aagcatgaaa tctaccaaca agagatcaga
      961 aagcaaaaac gtgccatgtt gtttcaacaa ggtagacaac aagaaaggga gtgaaatcgt
     1021 catgatgaaa accgttattt tagcagaaaa accgtcacaa gcgaaggctt atgccgatag
     1081 cttttctaaa gctacccgaa aagatgggta ttttgagatc caagatcgat tgttttcagg
     1141 agaaactgtg atcacgtatg gttttggtca tttagtcgag ttagattcgc ccgatatgta
     1201 cgatgaaaat tggaaacaat ggtcattaga gcatttgcct attttcccta cacattatca
     1261 ctatcatgtt cctaaagata agaaaaagca attcaaggtg gtgaaacagc aacttcaatc
     1321 ggccgacacc attattattg cgacagatag cgatcgtgaa ggggaactga tagcttggac
     1381 gatcattcaa caagcaggcg ccgatcatgg aaagatattt aaaagacttt ggatcaactc
     1441 cttagaaaaa gaagccattt atcagggatt ccagcagtta cgagatgcag aagagaccta
     1501 cccaaaattt gaagaagcac aagcacgcca gatcgccgat tggttgatcg gcatgaacgg
     1561 tagcccgctg tatagtttac tcttgcagca aaaaggcata ccaggaagtt tttccttagg
     1621 cagagtccaa accccaacgc tttacatgat ttatcaatta caggaaaaga ttagaaactt
     1681 ccaaaaagaa ccatattttg aaggaaaagc ccaagtaatc gctcaaaatg gcgcatttga
     1741 tgcgaagctt gatccgaatg aaacccaagc gacgcaagaa gcatttgaag attatttaaa
     1801 agaaaagggg gttcaattgg gaaaacagcc aggtacgatc caccaagttg aaaccgagaa
     1861 aaaaagtgcg gcaagtccac gtcttttttc tctatccagc cttcaatcta aaatgaatca
     1921 gctcatgaaa gctagtgcca aagatacttt ggaagccatg caagggttgt atgaagggaa
     1981 atatctaagc tacccacgaa cagatacccc ttatattaca gaaggggagt atgcgtatct
     2041 gttggatcac ttagacgaat acaaacactt tttaaaggcc gaagccattc ctactcctat
     2101 tcatacaccg aatagtcgat atgtgaataa taagaaagtc caggaacatt acgcgatcat
     2161 tcctacaaag acggtcatga cggcagcggc ttttgaacaa ttaagtccac tgcagcaggc
     2221 tatttatgaa caagtgttaa aaacaacggt ggccatgttt gcggaaaagt atacctatga
     2281 agaaacaacg atcttgacgc aagttcagca gcttcagcta aagacagtcg gaaaagtacc
     2341 agtagatcta ggttggaaaa agctgtttgg caaagagagc gacagaaaag aaaaggaaga
     2401 agaaccgcta cttcctaaag tgacaaaagg agaagcggtg acggtagatc tacaagtcct
     2461 tgaaaaagaa acgaagccac cacaacctta taccgaaggt acgttgatca cagcgatgaa
     2521 aacagctgga aaaaccgtgg atagcgaaga agcacaatcc atattgaaag aagtagaagg
     2581 aatcggtaca gaagcaacac gagcaaatat tattgaaact ttgaaacaaa aggaatatat
     2641 caaggtagaa aaaaataagc ttgtggtgac aaataaaggg attttacttt gccaagccgt
     2701 ggaaaaagag ccgctgctaa caagtgccga aatgaccgcc aaatgggaaa gttacttatt
     2761 aaagattggt gagcagaaag gaacacaagc tactttctta gctaatatcc aaaaatttgt
     2821 ctctcacttg ttggaagtcg taccgggaca aatccagtca acagattttg gatcaacgtt
     2881 acaagaggtg aaagcagcca gtgaaaaaca ggaagcaacg cgtcatttag gtgtttgtcc
     2941 aaaatgtcgg gaacaagaag tcttgcttta tcaaaatgtg gcggcatgta cgtctgaagc
     3001 ctgtgatttt aaattatgga caacgattgc caaaaagaaa ctcacagcca cacaactgaa
     3061 agagatcatt caaaacggcc gaacaagcca atcagtcaga ggactaaaag gtcagaaagg
     3121 ttcgtttgaa gcaacgatcg ttttaaaaga agactttaca acaggctttg aattttctga
     3181 aaagaaaaaa acgaactata agaaaagaac acgccgcact acaaaataat gaaggggtta
     3241 tcctatgcga aatacaacac acaaacaaca agaaatcgaa aatcaaaaag caaaaattcg
     3301 tttagaacaa gagaaattac gtgcaaataa aagaagactg caacaattaa agaaccagca
     3361 gcgcattcaa aaagaaatcg aattagatcg atagacgtta atcttgttac aaataaacta
     3421 ctatgatata tttgatgtag tgtatttgta acgaagggag gggaagtaaa tgcaagataa
     3481 actgaaagaa ttgttggcta ttcgcgatgg aaatttatct atgaaggaag ccaggaaatt
     3541 tggaatcgca gcaaccactg tacaaagatt ggtgaatcaa ggaaaattga tcaaagttga
     3601 tcgtggttat tatgtagagg atggtcatgg aatagatgat ttattttggc ttcagcaacg
     3661 attttccagg ggaatcttct ctcatgaaac gactttagat atttaccagc tttctacgaa
     3721 tatgccgaaa ttcattcact taacttttcc ccatggctat aacgttgatc gttcaattac
     3781 aaaagagcag cagttacaat ttcatttcgt gaagaaagaa gtttatgaac taggaaaagt
     3841 agagggaact tcctttcaag gaaatcctat tactatgtat gataaagagc gtacactttg
     3901 tgatatttgg aatccgagat atgaatttga atatgaaatg aaattagaag cattaaaaga
     3961 gtacatggaa gacccattga gagatccaag taaattaaga gattacatga caaaactaca
     4021 tgtagaaaaa gaaatgaaat accacatgca aagcttatat tgatggagga aaaagatgac
     4081 accgacacaa tttgcagcaa aaacaagaaa tttagcaaag agtacaggat taaatgcaca
     4141 gttagtgcaa cggcatttta tgatggatcg tctaattgaa caaatttctg aatcaaagta
     4201 caaaaatgac ttcattttga aaggcggctt tttattagga tcaaaatatg gaatcgatag
     4261 aaggacaaca attgatatcg atacgacatt tagaaatagc aaattaactg aagaaaaatt
     4321 gaagagcatt tttaatgatt taactagaaa acccacaaaa gaaggcattg ttttctctat
     4381 tcaaggaatg aaggaaacaa gagaagccga tttttatcct ggatttcaaa ttaaattggt
     4441 ggctaattta gagaaagtac gtgtaccgtt taaaatggac gtgacaacag gagattctat
     4501 ttatcctgaa gtagatacac actatcacca attaatgttt gaagataaaa aagtggagat
     4561 tccagcttat ccaacagaac aaattattgc agaaaagcta agtgctacgt tcagctttgg
     4621 cacagataat tcgagagcaa aagattacta cgacttattt accattccga aactagaaaa
     4681 tatcgatacg aaagagttat acaaaagtgt tcgaaataca tttacaaaac gtggggatac
     4741 aaaaccgttg tccttttatt atgaaagaga aatggataag atcagaggaa atgactattt
     4801 ggaaaagcag tgggaaaaat atcgctcagt taacacgttt gcgaattcca tttcatttac
     4861 agatacagtc aacgaaattg atcacctaat gaaaagtgtg atcaaaattg aaaatcaaga
     4921 aagaaaacgg cagtttaaaa gatcacaaca aatgaatcaa gaaatggaga gataaagatg
     4981 attaataatg tgacattagt aggacgctta accaaagatc ccgatttacg ttatactgca
     5041 agtggcacag cagtagcgac ttttacccta gccgtcaacc gaaatttcgc gaatcaaaac
     5101 ggcaatcgag aagccgattt tattaactgc gtgatttggc gcaaaccagc agaaacaatg
     5161 gcgacattag ctaaaaaagg cggcttgatc ggtgttgtcg gacggattca aacacgaact
     5221 tatgacaacc agcaaggaca acgtgtgtat gtgactgaag ttgtagcaga taactttcaa
     5281 ctattagaaa gtaaagcagc gacagagagc cgtgcgcacg ctgatcaatc aaccaccagt
     5341 ccaagcccca ctacctttga acaacgggat acaaacaatg gattggacgc ttcacaaaat
     5401 ccatttggtg gacaatcaat cgatattagc gatgatgatc taccattcta agtagcattt
     5461 tctattggtt gcatttgcta cggtttatgt tataatttag tcaacaaaaa gaattttcaa
     5521 tctataacca aaaaccacta gctggcgggc tagtggtttt cttttacgtt tctattataa
     5581 gaattaacgg gtaggcttac tgtctttctt ggcaaattta caatcaagcc atttgcagat
     5641 atagtgcgcg gctacttctg ccatgattgc aaaaacaaaa tcaaaaagaa ttttcaaacc
     5701 tataacctcc tccccttgcc agattaggcc ggggtagcag acagcaagac tattatagca
     5761 taattgaaat attcaaatga ttggattttt gctataattt tagcgaggtg attgtgatga
     5821 acaaatatgt tggtttgctt gataaaatcc gagtaataaa aacgcaaccg ttattggttc
     5881 gctttacttt acaaacgatt catgaatcga ttaattgtgt agttgcagat attgaaatta
     5941 tcgataaatt gctaattatg gatgatggaa aatacaatat tgccgtcaca ggtcacttca
     6001 ataaacgaaa ccagctagtt attgctagca tgtatgttag aaatcccgat cagtttacgc
     6061 gattgatggg catataaaaa aagaagagtt gcaatcctaa tgtaggactg cagctctttt
     6121 tgttttacat agaaacaaga aaaatgaaaa ggccttttta ggaaggcgcg agcgccttct
     6181 caattgaaaa acctctctca ctccaaccgc caccgccgtt cgagaagaaa ggaagtgaac
     6241 gttgcacgtt cactaagata aagggtcttg caaagcaaga caaaatagaa aaaacttcct
     6301 ctcaccaaaa ggttcgttcc tgttcgttat ctctttattg atttgccaga ccggcaacaa
     6361 gttgcctttt atcaccaaaa agcgacaagg acaagggtaa atggcacgct gcgcgccctt
     6421 gtccttgtcg cttttcgttg attcattctg gccaacaaat caataaagaa agaactaacg
     6481 aaaggaagta aaacctttcc taagaggagg cagaatcaat catgcgaaag aaatttgatt
     6541 attggggtgt tcccttcagc gaattattcc caaactatca tgcaccacat actgtcgaat
     6601 gcgattgtgg agaaagagcg aaatgtatca aaagctatcg tttgtatcaa tgtccaacat
     6661 gcgggaaaaa atataccttg tcttatggcg attatatttt gattgatgag aaaggaaaga
     6721 aacgttgatg aaaacacaac acaaattatt gactgtaaaa gaagtcgttc aaattttggt
     6781 ggacaaagaa gtcatttctg aaaaagtagc agaagcttta cttattccgc ggtactggac
     6841 gacagaaacc cctttagtag aggatgcacc gactatgcta tttgaagacc tagtgaagat
     6901 tgcaggatat gaactgcatt atcaagaaaa cttggaaact tatgaaaacg aatattggtt
     6961 aaccgaatta gagaactaaa aaggagaaaa aaatatggct caaaattact atgacgaatt
     7021 tgtcaaatta cctttggata aaatggcaca aaaaatggag gatatgacat tcctatacaa
     7081 tgagacacgt gttccaaaaa aacattataa ggaaagattg tcggtagctg tggaagaaat
     7141 gattgaatca ggtgtcgaaa tgaatctcat tgcgacgtat tatcgaacac tggaagaact
     7201 gaaaaagcaa aatgcaaaat ggtttttcca agccttacta tgcttggaag taggcgtcaa
     7261 accaagcaca atcaaacctt ctgaatacca agctttagaa ctaacgtatg cgaaatttat
     7321 cgaaacgaaa aaagctaaga ctgtttcaag tgaatggtta gattattttg aaaatatcaa
     7381 taagtatggc gcatgttaca tcatgaagta atcagacgga ttcaaaaaga ctttagttgt
     7441 atggaagaaa tgaagtactt tgttcaaaat gttgaagaac agttatattt ggaaagcgaa
     7501 acgagtcaaa caaaggtcac agtcagccat aatcgtttag atgtgtataa acgtcgtcct
     7561 gaatcattaa aaaaaggagc ggagcttcta cgactagaaa cagaaaaata cgtcatgaat
     7621 gtttacctag aaaaaagtga gttggtcgaa aattttatgg actagccgag aacacccgtg
     7681 attttaatca tgggatgaat cggattcagt tgtgacctag ctttagctag gttaaacaac
     7741 tgacaaatat aaactaaata atagtgaaat gtcttgcaat aattgatttt gtagaaatac
     7801 atatattaaa ataattgcga ggtgtttttg tatgtcagaa attcattatg gacggggtta
     7861 tgtctattct attcaatatc atcttgtttg gtgtgtaaaa tatcgacatg atgttttgta
     7921 tggtcaggta gatattgatg tcaaacagtt tttgaaacaa attgctgatg ataataatat
     7981 aaaaattata gaaatagaat cagataaaga ccatattcat ttactcattg aatgcacccc
     8041 acaacactat attcctagta ttgttaaagt atttaaaggc gcatccgcta gactgctgtt
     8101 taaaaaacat cctgaactta aacaactcct ttggggtgga catctttgga atccaagcta
     8161 ctttgtagct actgttagcg aaaatacaga agaacaaatt agaaaatata tacaaaatca
     8221 gaaaaagaaa tgaggtgaat ccgtatgcta caacataggg cttataaatt tagaatctat
     8281 cctaatcaag aacaagaaat attaatgact aaaactattg gctgttcaag atttgtctat
     8341 aattattttt tgaatttgtg gaatcatgaa tatacgacta ctggaaaagg attatcttat
     8401 aattcttgtt ctgccatgct tccacaaatg aaaagaaatg cagagacaat ttggttaaaa
     8461 gaagttgaca gtattgcgat tcaatcctca ttgaaaaatc tttctgatgc tttttctcgc
     8521 ttctttaaaa agcaaaataa acgaccacaa tttaaaagta aaaaacatcc tatacaaagt
     8581 tatacaacta aaaatgtgaa taatagtatc gaaattagaa acaatttcgt aaaactacct
     8641 aagttaggat ttgttaaatt tgcgaaaagt caagagccca aagggcgaat cttaaatgct
     8701 acgattcgaa aaaattcgag tggtaaattt tttgtttcca tcctgtgtga agaagaaata
     8761 gttgagtttc ctaaatctaa ttccgctatt ggaatcgacc ttggtataac tgattttgca
     8821 atcctttctg atggtcaaaa gattgataac aataaattca cgtcaaaaat ggcaaaaaaa
     8881 ctcaaacgtg aacaacgtaa gttgtcaaaa cgtgcattac tagctaaaaa gaaaggcgtc
     8941 aatctctttg aagctaaaaa ttatcaaaaa caaaaacgaa aagtagcacg actacatgaa
     9001 aaagtaatga atcaacgcaa tgacttttta aacaagttga gcacagagat tatcaaaaac
     9061 cacgatatta tctgtataga agacttaaat acaaaaggta tgttgcgtaa tcataaacta
     9121 gcaaaaagca tttctgatgt gtcttggtct agttttgtga ctaagttaca atacaaagct
     9181 aactggtacg gtcggaaaat catcaaagta gataaatggt ttccatctag tcaaatctgt
     9241 tcaaattgtg gacacaaaga cggcaagaaa tctctagaaa ttcgagaatg gacttgtcct
     9301 gtttgtcatg ctcatcatga ccgagatatc aatgctagta tcaatatttt gaccgaaggt
     9361 ctaagattac atgtcatggg attagcttag atccaatcat caaaaaccgt aggaactacg
     9421 gggatagctt ggtaaataag agaaaccgct gtgagtaaag aaatacgctt gcaagtatgc
     9481 tctattccca agaatctcgt gactttagtc atgagaggtt caaggattca tggaatgtta
     9541 atctaattta atagaaaagg ataattaagt atatacgttt tttcttatgt atgttatact
     9601 atgtatatac agaaagaggt gtctactatg gaaatgttac ctataaaaaa atggggaaat
     9661 agtaatggcc ttagattgcc aaagtatatt atggaatatc ttggaattca tacagaagac
     9721 aaagtgaaga taatacaaga agaagtaaac ggtcagaagc ggctaattat cgaagcggct
     9781 aatatagaaa atgaattaac aattgaacag ttatttgaaa attacactga tgaaagaaat
     9841 catgtgacga ttcaaaattt aggtgaagca gtaggtaatg aaaaatggtg agaaaaccta
     9901 gacaaggcga tattctatta ttgaatacag cacctcgatc tggacacgaa cagacaggta
     9961 aaagacctta tattgtttta agtcatgata ttattgcgga ttatagtaac gttgttacag
    10021 ttgctccaat ttctagtaca actagaaact atccgctata tgtaaatata aactcagaat
    10081 atgaaatgaa gacaacagga aaagtattat tagatcaact aacgacaatt gattatgaag
    10141 ccagagagtg tatttttttg gaaaaagcgc atgatagttt agttgaggag ttattgatga
    10201 aagttagaac agtttttcaa aaagtaagca aataaaatag aaacagcagc atgatcaact
    10261 attc
//
LOCUS       DAFEEZ010000086         9905 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000086
VERSION     DAFEEZ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.089"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..1197
                     /locus_tag="LP245_002543"
     CDS             <1..1197
                     /locus_tag="LP245_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL1520418.1"
                     /translation="ATKLDDKSDADKYNPEGQKVTTELNKEPDASEAIKNKKDLPKDT
                     KYTWKEKVDVSTAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSNADKYNPEGQKVTTD
                     LNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVT
                     VTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNK
                     KGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLP
                     DGSQYHGTADKNGNFTVKVPKLEAGTKVRVTATDESGNTSEPTNVVVSSNKKDSGKNG
                     SKGSKTDNQDGNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKN
                     RKKENE"
     gene            1331..2674
                     /locus_tag="LP245_002544"
     CDS             1331..2674
                     /locus_tag="LP245_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL1520419.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKLILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDNTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GKEKIEKIVTTRDNKYAMDMVIQAIGFLSHSPIGKKEFLRDVSGAYLTDEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINDQSFTPSGSQFTNGFSIFG
                     YNFYAAGLNLKTARLLSEAIDYIEIEDYIRPIFSKTNNIVKLRISFEKKAKRIVGVQF
                     YSQEDLSGLLTMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNSGA"
     gene            2786..4189
                     /locus_tag="LP245_002545"
     CDS             2786..4189
                     /locus_tag="LP245_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBL1520420.1"
                     /translation="MKKSLKLASAVLLMSHLLIATPFHVLASENSTYKIAKERTKTTE
                     MSNSDVTAEGSEFSTTSSSESSTTLNAESSTTSSSESSMTSNAESSTTSSSESSTISS
                     TESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFSTSQQIESTETFQSQPV
                     LSGNEEIHFDKNESVENFIMKIGDSARKIGQKYDLYASVMIAQAILESASGQSQLAQA
                     PNYNLFGIKGTYNGSFVIMVTNEDLGNGTLYKTQSKFRVYENYEESFEDYAKLLTKGI
                     SGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNGLIKTYDLTDYDKEVQGP
                     QMNKNGYQIPIHNYSISSLFGNRGDEFHRGLDMAAAQGEPIHAVKAGKVIKAEFHYSW
                     GNYVVIQHEDGSTALYAHQQQYLVKTGDNVVQGQMIGYVGSTGNSTGPHLHLEICKDS
                     SLSQSMLVDPKTLLFGN"
     gene            4607..4822
                     /locus_tag="LP245_002546"
     CDS             4607..4822
                     /locus_tag="LP245_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520421.1"
                     /translation="MNQEIADIKLIKEVLQESTANAIASGSGISLSTAKKLKSGERNV
                     EKLNLSDAIKITEFAIKNRHVKIEIWK"
     gene            complement(4908..5819)
                     /locus_tag="LP245_002547"
     CDS             complement(4908..5819)
                     /locus_tag="LP245_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1520422.1"
                     /translation="MKIKIERNQKEKSPKKNKERVISVGKHRKMVLALWLLLSCSLAF
                     GIYRNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWRNNKEAIEKRMSNL
                     EQYLTENGLALSQDMVRADIPTSSEVQSIKILDVEKHSEEFIVSFLVEQQITEGKKTQ
                     SISSAYRVTIFEDENGSHIVTSLPTMIAKPEKAKYESKQIGIESDIDAKTTEEVTDFL
                     ETFFKLYPSASEKELEYYVENKAVQPINSNLKLVELVNPTFKLKGKEIQGEIFVKYLN
                     NTTKVSNIFEFTLTLQKVKNWKIIDIG"
     gene            complement(5838..6842)
                     /locus_tag="LP245_002548"
     CDS             complement(5838..6842)
                     /locus_tag="LP245_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBL1520423.1"
                     /translation="MNVKKLSIISLTILTLSFMVVLMCVGLLFGEDSEGSNSSGASSG
                     GSNVSEEVLKHRAMVEKYAKESNISEYVLILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVAKNGKKHNFALA
                     ESFSKEKSSGQKVDYPNPIAIKKNGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGASPETGFDCSGLTQWCYAKVGLKLPRVAQDQYNAMTHIDVKDA
                     KPGDLVFFHSTYDTGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            complement(6839..8962)
                     /locus_tag="LP245_002549"
     CDS             complement(6839..8962)
                     /locus_tag="LP245_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL1520424.1"
                     /translation="MKKKLLRIVGIIAISLCTILLLLSLIGTVAEATGLVDDTVKSGN
                     LYSQYSLDNYQLDFFVDSSWGWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQVSGFYFGFLLLMILALGVYVAYI
                     GLLKREATKAVRAVINFVTIFLLSGSFIAYAPTYITKINNFSSDVSEAALSLGTELVV
                     PNSESKGKDSVDLIRDSLFSIQVRQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRIMRKPHMLMNRKLR
                     QLNRNVIRTLAFGGGAAVGHKLEKEQSKSKFKPSGSSLRKNSRLPNDHEVPSDSTKEN
                     PVSNNKKQSRMNLAGRKMGKVLDTQALVKDKTKQVRDQVRNTPTNLKYNFHKGIEKTK
                     KAPKEFKRGLVQEKANRAELREKQRQHRDEKMAEKRKVLNETGNRHKKRRENVSIKPE
                     RQPQKDRAPKKEAPKQIVRVNPNPEIKRKLSSHEIVSKRISQPSSKKNSFQQVKQRST
                     LPKRTNQKVQKRMNPRPKSRSGEKK"
     gene            complement(8967..9878)
                     /locus_tag="LP245_002550"
     CDS             complement(8967..9878)
                     /locus_tag="LP245_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1520425.1"
                     /translation="MASEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLT
                     GISSRDGEKFPVLRKAIRTVTQSNQRGLLQVITELRNDGTPVAENIADHIESFTDYDF
                     AHLLFSDGSITQSISLEKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFA
                     LDFIHSNREIFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLD
                     ERLKNNIGLKFAFRSTDIHEIKKTLEFFGLDQEDESNQKRLRDLENGQCLMQDLYGRV
                     GVVQVHPVFEELFHAFDTRPPVQKRME"
BASE COUNT         3352 a         1763 c         1750 g         3040 t
ORIGIN      
        1 gcaacaaaac tggatgataa atctgacgct gacaagtata atcctgaagg tcaaaaagtg
       61 actacagaat tgaataaaga accagacgca tctgaggcaa ttaaaaataa gaaagattta
      121 ccaaaagata ctaagtatac ttggaaagaa aaagtagatg ttagcacagc tggaaataaa
      181 aaaggtactg ttgtagtgac atatccagat ggatcatctg atgaagttga agtggatgtt
      241 acagtgacag acaatcgttc taatgcagat aaatacaatc ctgaaggaca aaaagtgacg
      301 acagacttaa ataaagagcc agatgcatct gagggaatta agaacaaaga agatttacca
      361 aaaggaacta cttatgcttg gaaagagaaa gtagatgtta gcacagctgg aaacaaaaaa
      421 ggtactattg tagtgacata tccagatgga tcatctgatg aagttgaagt agacgttaca
      481 gtgacagata ctcgttccga tgcagataaa tacaatcctg aaggacaaaa agtgacgaca
      541 gacttaaata aagagccaga tgcatctgag ggaattaaga acaaagaaga tttaccaaaa
      601 ggaactactt atacttggaa agaaaaagta gatgttagta cagctggaaa caaaaaaggc
      661 actgttgtag taacatatcc agatggatct aaagaagaag tagaagttac tatttctgta
      721 gtagataaaa aagcaccgaa taaacctcaa gttgatccta ttacagaggg tgaccaaatt
      781 gttactggta aaactgaacc aaatgcagag gtaacagtta cattaccaga cggaagtcaa
      841 taccatggga cagctgataa gaatggtaat tttacagtta aagttcctaa attagaggca
      901 gggacaaaag tgagagtaac tgcaacggat gaatctggta atactagtga acctactaat
      961 gtagttgttt cttccaacaa aaaagacagt ggaaaaaacg gtagtaaagg tagtaagacg
     1021 gacaatcaag atggcaatag caatcaagac aaaaatagag gcaaaagcca gtcctcaaaa
     1081 gtttttccta agacgggaga gagtgacagt aatatcttta ctattagcgg tggtttaata
     1141 ctgttaggaa cgttaggatt attagggtat aaaaatcgaa aaaaagagaa tgaatagaaa
     1201 atcaatttct taagtcttct ctgagaagag gaagaatctt tttcttcctc tttttgcttt
     1261 tttatgatgg gaaataagtg ttagttaaag atgaatatac tttttataga aaggaaaaga
     1321 atgtaattaa gtggaaaaaa tagtaattat tggttcaaac cattcagggc tagccgcagc
     1381 tcgatttcta aacttaagcg attcaaatta tgaagttatt ctaatcgata aaaaatcaga
     1441 aattagttac ttggaatgtg ggacatcgtt atttataaaa ggagaagtaa gtaatttaga
     1501 agatcttttt tatcaaaata gaatgacact aaattctgag ataaaaaagt tatttctaga
     1561 gacagaagtt gacaaaattg atattcaaaa taaaaagatt agttgtgtaa aaaaagatgg
     1621 cacaagattt tcccaagaat atgacaaact tatattagct acaggttcaa agcaaattat
     1681 gttagatata ccggggaata atttagctaa tattttttcg ataaagaatt ttccaaatgc
     1741 caaagagatt ttcaaagctt tagatgataa tactattaaa aaagtaggta ttattggagc
     1801 aggatatatt ggagttgaaa ttgctgaagc tataagaaaa agagggaaag aagtatatct
     1861 tttcgatgtt gcagatagag tgttgtcgac ctattacgac cgtagttttt cagataaagt
     1921 tgaagaaata ctatcaaaaa acgggataca tctttgtcta tcagaaagtc ctaaaaagta
     1981 tttaggaaaa gaaaagattg aaaaaatagt gactacaaga gataacaaat acgctatgga
     2041 tatggtcata caagctatag gattcctatc tcatagtcca ataggaaaaa aggagttctt
     2101 gagagatgtt agtggagcat atctaacgga tgaataccaa caaacaaata taaaagacat
     2161 atatgctatt ggagattgtg ctacaacttt ttttacatcc attaatagaa gtagcgttga
     2221 tttttctatc tctaatgctc taagaacggc ttatattgca actcaacata ttaacgatca
     2281 aagttttaca ccttcggggt ctcaattcac aaatggcttt tctatatttg gttacaattt
     2341 ttatgcagca ggtttgaatt taaaaacagc acgcttatta agcgaggcta tagattatat
     2401 agaaatagaa gattatatta gaccgatttt ttctaaaaca aacaatattg taaaattaag
     2461 aattagtttt gaaaaaaaag caaagagaat agtaggtgta caattttata gtcaagaaga
     2521 tctatctgga ttattgacaa tgttctctct tgctatagaa gaacaaatta cattagacaa
     2581 attgaaaatg ttagattatt tatttcatcc tagttttagt caaccctata attttatttt
     2641 aaaggcagta acaggattaa atagtggagc ataatcgtta ttaaatgaaa tcaagaaata
     2701 tactgtatta ctcaattcat tgaaaatatt tgtcatattt tttaatagaa aacactatta
     2761 aagaaaaaaa agagaggtaa atcaaatgaa aaaatcttta aaacttgcat cagcagttct
     2821 attaatgtcc catctcctta tagcaacacc tttccatgtg ttggcaagcg aaaattcaac
     2881 atacaaaatt gcaaaagaaa gaaccaagac gactgaaatg agtaattccg atgtaacagc
     2941 agagggtagt gaattttcaa caacttcatc aagtgaaagt agtacgactt taaatgctga
     3001 gtcttcaaca acttcatcaa gtgaaagtag tatgacttca aatgccgagt cttcaacaac
     3061 ttcatcaagt gaaagtagta cgatttcaag taccgaatct tcaacaactt caagtagtac
     3121 aagtgaaata acttcttcga aagttacaaa gccaaaccat atagagtctt caaaaaagga
     3181 agcgccaaaa acggaaggac aaacaaaaac tttttcgaca tcacagcaaa tagaatcaac
     3241 agaaactttc caatcacaac cagtactatc tggtaatgaa gaaattcatt ttgacaaaaa
     3301 tgagtctgta gaaaatttta ttatgaaaat tggtgattct gcgagaaaaa ttggtcagaa
     3361 atatgattta tatgcttctg ttatgattgc acaagcaatc ttagaatctg ccagtggtca
     3421 aagccaatta gctcaggcac cgaattacaa tttatttggg ataaaaggaa cttataatgg
     3481 aagctttgtc ataatggtaa caaacgaaga tttgggtaat ggaacgcttt ataagactca
     3541 atcgaaattt agagtgtatg aaaactatga ggaaagtttt gaagattatg ccaaattatt
     3601 aactaaggga attagtggaa ataaagattt ttatgccgga gcattaaaag ctaatagtaa
     3661 aacatatcga gaagcaacta aattccttac aggacggtat gcaacagata ctcaatacta
     3721 tttaaagcta aatggattaa ttaaaaccta tgatttaact gactatgaca aagaagttca
     3781 aggaccacaa atgaataaga acggatatca aatacctatt cataattatt caatatctag
     3841 tttgtttgga aatcgtggag atgagttcca tcgaggactt gatatggcag ctgcacaagg
     3901 tgaaccgatt catgcagtta aagctggtaa agttattaaa gcagagtttc actattcttg
     3961 gggaaattac gttgttatac aacacgaaga tggatcaaca gcgttatatg ctcaccaaca
     4021 acaatactta gtaaaaactg gagacaacgt tgtgcaagga caaatgattg gctatgtagg
     4081 aagtactggg aatagtacag gaccacacct ccatttggaa atttgcaaag atagtagtct
     4141 ttctcaaagc atgttagttg atccgaaaac cttattattt gggaactaaa aagaaaaaga
     4201 gcattttatt agaagtatgg attagggaat atagtagtag tgggctctaa agattatgaa
     4261 atctttaaga gctcttttta agacgattgt ttaaaacgaa ttaaccaagt aggagctttc
     4321 ctagaattta taaaattata gtttcttgta tgacatgtat atagcatgct aaaataccaa
     4381 taaataaggt ttaagataaa cgcaaaaagt cgaaaaatta acacttattt tgtgatatta
     4441 attttaattt gcaaaacaag ctatatggaa aaagtttaaa ctttttctag agtccctatt
     4501 actagttaaa aagaccactg tagtcctctg ataaatcatc ataaagacca cagtagtccc
     4561 cttaaagttt ttccaaatta actatctgag aaaggagaga agatttttga atcaagaaat
     4621 agctgatatt aaattaatca aagaagtttt acaagaatct accgcaaacg cgatagcatc
     4681 tggatcaggg attagcttaa gtacagcaaa aaaactaaaa agtggcgaga gaaatgtaga
     4741 aaaactaaat ctttctgatg caataaaaat cactgagttt gctattaaga ataggcatgt
     4801 gaaaattgaa atttggaaat gacggataca actattatag ttttgttttt tctaagtatc
     4861 atatttatga atatgctttt gctaaacatc taattataga ttaattttta tccaatatct
     4921 ataattttcc aattttttac cttttggaga gtaagggtaa attcaaagat attgcttact
     4981 ttagttgtat tattaagata cttaacaaaa atttctcctt gaatttcttt tcctttcagt
     5041 ttaaaagtag gattaaccaa ttcaactaat ttcaaattac tattaattgg ctgaactgct
     5101 ttgttttcaa catagtattc aagttccttt tccgatgctg atggatacag tttaaaaaag
     5161 gtctctaaaa aatcggtgac ttcttccgtg gttttagcat caatgtcaga ttcgattcct
     5221 atttgttttg attcatattt tgccttttct ggctttgcaa tcatagtagg caaactcgtt
     5281 actatatggc tcccattttc atcttcaaag attgtcactc gatatgcaga agaaattgat
     5341 tgtgtctttt ttccctctgt aatctgttgc tcgactaaaa atgaaacgat aaattcttcc
     5401 gagtgttttt caacatctag aatttttata gattgaactt cggaactcgt gggaatatct
     5461 gctcgaacca tatcttggct taaagcgaga ccgttttctg taaggtactg ttcgagatta
     5521 ctcattctct tttcaattgc ttccttgtta tttctccatg aaaaatattc tttcgcaaaa
     5581 tcctctgtaa aactttcaac gcctgaagta ttcactacct tctcttttat aactactttt
     5641 tcatgagtcg tatgctgatc aatggctgtg aaatttctgt agattccaaa agcaaggcta
     5701 caagacaata aaagccaaag agcaagcacc atttttcgat gcttgcccac tgaaatgact
     5761 cgttctttat tcttttttgg gctcttttcc ttttgattcc gttcaatttt tatcttcatg
     5821 ttttttcctc ttttctctta tttgtaccgt ccagcaccga taagatgctg ctgccaatag
     5881 ctttctgtta gatttgtcca gcccactgga tctcctgcat gaaacatgcg attctctcct
     5941 gcataaatac cgacatgggt cacataagta ccggtatcat aagtcgaatg aaagaaaacc
     6001 aaatcacctg gtttggcatc ttttacatca atatgggtca tggcattata ctgatcttga
     6061 gccacccgag gaagtttcag accaactttg gcataacacc attgagtcaa gccactacaa
     6121 tcaaacccag tttcgggact tgctccacca aacacataag ccgttccttc atacttaaac
     6181 gcctcatcaa aaatcccttg gactgtttta tcatcaaact gtgttgtagt taggtattgc
     6241 ttcactaata agcaataaaa catattgcca tagttatacc gccacccacc atttttctta
     6301 atcgctatgg gattagggta atcaactttt tggccgctcg atttttcctt tgaaaaagat
     6361 tcggctaaag caaaattatg cttcttcccg tttttcgcga catgatccag atacccgcca
     6421 ccatagttat acgcttgaat aatgctatct tgatcacacc ctagttcttt ggaacgctta
     6481 accaaagacg caaaatagag acatccttgt ttgatggatg cctcggtact taatgaattc
     6541 ggtggcaacc cggctgactc cgaactctgc atcacatctt ccattgtgcc accagattcc
     6601 acttgaataa tcgccaaaag aatcaggaca tattctgaga tgtttgattc cttggcatat
     6661 ttttccacca ttgctcggtg tttcaaaact tcttctgaga cattacttcc cccagaagaa
     6721 gcacctgaac tattacttcc ttcactgtct tccccaaaca acaagcccac acacatcaag
     6781 acgaccataa aggagagtgt caagatggtt aacgaaatga tacttaattt ctttacattc
     6841 attttttctc acccgacctt gattttggac gagggttcat tcttttttgt actttttgat
     6901 tggttcgctt gggcagagta gacctctgtt tcacttgttg gaaagaattt ttcttacttg
     6961 atggttgact tattcttttt gaaacaattt catgactaga tagttttcgt ttgatttcgg
     7021 gattcggatt tactctcaca atctgttttg gtgcttcttt ttttggcgct ctatcttttt
     7081 gaggttggcg ctctggtttt atcgaaacat tttcccttct tttcttatga cgattaccgg
     7141 tttcgttcaa tactttgcgc ttttcagcca ttttttcatc tctatgttgt cgttgttttt
     7201 ctctcaactc cgctcgattt gctttttctt ggacaagtcc gcgcttgaat tctttcggtg
     7261 cttttttcgt cttttcaatt cctttgtgga agttgtattt caagttggtc ggcgtattcc
     7321 ttacctgatc ccttacttgt ttagtcttat ctttcaccaa agcttgggta tccagaactt
     7381 tgcccatttt tctcccagcc aaattcattc gggattgttt cttattattt gaaactggat
     7441 tctccttagt cgagtcagat ggtacctcgt gatcgttagg taatcgtgaa ttctttcgta
     7501 gagaagaacc ggatggctta aatttggatt ttgattgttc cttttccaac ttatgtccaa
     7561 ctgctgcacc accgccaaaa gccagagttc ggatcacatt tcgattgagt tgccgcaatt
     7621 tacggttcat caacatgtgc ggtttccgca tgatgcgcct tcccattgac tgactatcat
     7681 tgctttggag attgaacata ctcatgatgt cacctaattt gaaatagata ccggcaaagg
     7741 tcacgatttg caggaacgca accataaaga aaggataggt agctgaaata ttgaaaaaca
     7801 tggtggagat actaaaagca gtcgtaatga ctaaggtaac tcccgctcgc atcataatcg
     7861 tattgaataa acgaataatc gccttctttc ccaagctctc ataagttggt aacatggata
     7921 acagaaaact aattggcaga aacatggcga aaatgataaa gagaatttgg gagaacaaca
     7981 taatccccgt cagtaagaag acaaagaatg agataccaat attaaacaac accaaaaaga
     8041 ccacggtccc tagtcggttc atggtctttg taatacttag attcgcgttg tcattgtctt
     8101 caatttcagc ttttaccgct tcttctcgat cctttccctt attttcatct ggactcacag
     8161 ataaaatttt attgacccgg tcttcaccaa tttcttctat gttggaatca tcaaattgca
     8221 acaagagcca aggttgtcgg acttgaatag aaaacaaact atcacgaatc aaatccacac
     8281 tgtcttttcc tttgctttcc gaattcggca caacgagctc tgttccgaga ctaagagccg
     8341 cttcactaac atccgaacta aagttattga tttttgtgat ataggtaggc gcatacgcga
     8401 taaaggaacc agagagaagg aagatcgtta caaagttaat gacagcccgg actgctttgg
     8461 tagcttctcg ctttaatagt ccgatatacg ccacatagac tcctagagct aaaatcatta
     8521 ataatagaaa tccaaaatag aaacccgaga cctgtaatcc attttcagta ataccggcta
     8581 gcgtttggat atttttccca atactttctg ccgtatccga aataaaatct aatttgtacg
     8641 cttcttgtac cacatacccg gtcgcatttg ataaatacaa actaacggtc caaatgaaat
     8701 ttgtaatggc gtagagaccg tacatcacac tctttcctaa cccatcgccc cagttccaag
     8761 gcagccagcc ccacgaacta tctacaaaga aatccaattg atagttatca agtgaatatt
     8821 gagaatagag attgccagat ttaacggtat catcaactaa tccagttgct tccgctactg
     8881 ttccaatcag actcaaaaga agtaaaatgg tgcagagact aattgcaatt attcccacaa
     8941 tccgtaaaag tttctttttc atctcctcac tccattctct tttgaacagg cgggcgtgta
     9001 tcaaaagcat ggaagagttc ttcaaagact ggatgcactt gtaccacacc aacgcgacca
     9061 tacaagtcct gcatcaaaca ttgcccattt tccaaatctc gcagacgctt ttgattgctt
     9121 tcatcttctt gatcaagacc aaagaattcg agtgtcttct tgatttcatg aatatctgtg
     9181 cttcgaaagg caaatttcag cccaatgttg tttttcagac gttcatctaa taaatcatca
     9241 ctattttgag tgacaaagta aacgccggca ttcatagcac ggccagcacg aactagttta
     9301 ttcgaaagag tttttccttg tgcgacttga aggaagctcc aggcttcatc caaatccacg
     9361 attttgaaaa tttctcgatt gctatgaata aaatccaagg caaatgtgga gataacaatc
     9421 aacatggaaa cactaagcaa ttccatcgta gtgtactctt caaatgtagt ctccgcatcc
     9481 ggcaaaacca aatctgccac ctgaatgata ttcaattgtt tctctaaact aatcgattgt
     9541 gtaattgaac catctgaaaa aagtaaatgc gcaaaatcat aatcggtaaa cgattcaata
     9601 tgatcagcaa tattttccgc aactggtgtc ccatcatttc gaagctcggt aatgacttgt
     9661 aacaacccac gttgattgct ttgggtaacg gttcgaatag cttttcgtaa aacgggaaat
     9721 ttctctccat cccgactaga aattccagtt agaaaagtca gaatatcaat tgctagactt
     9781 tcagaatcct tctttttctt catgatcaca tagggatcaa gtaacccttg attttctggt
     9841 ttactggtta ggttgaggat attaatttca ctcgcaattt ctggtaaggt ttctttccag
     9901 ctacc
//
LOCUS       DAFEEZ010000087         9701 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000087
VERSION     DAFEEZ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9701
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.090"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..1023
                     /locus_tag="LP245_002551"
     CDS             <1..1023
                     /locus_tag="LP245_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBL1520426.1"
                     /translation="ELKPKHERQNFLVGDDRLDHAVAFLWKDPQTGETVGASYQGTIV
                     DFNRFGKRGTYKHIDKNPTPNHGFNLKIGDPKHLKFFESSIDLLSYAALNREKLQDAW
                     LVSMDGLKHHVISHYVEESISELRRKQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDP
                     FTNKKIRCERGIPNDWQVPKEYKATYEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVS
                     AHDVQSTFGKMLAKGEPVETIDLKEACTTVAKELKVCERADGTYNFDRFYSRKANIKD
                     VNAGILLSYKAEQYYKGYKKHEHEFVPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQG
                     RQQERE"
     gene            1034..3043
                     /gene="topB"
                     /locus_tag="LP245_002552"
     CDS             1034..3043
                     /gene="topB"
                     /locus_tag="LP245_002552"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL1520427.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKRSEGFI"
     gene            3159..3308
                     /locus_tag="LP245_002553"
     CDS             3159..3308
                     /locus_tag="LP245_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520428.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            3389..3985
                     /locus_tag="LP245_002554"
     CDS             3389..3985
                     /locus_tag="LP245_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBL1520429.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPEKTLCDIWNPWYNVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            3998..4897
                     /locus_tag="LP245_002555"
     CDS             3998..4897
                     /locus_tag="LP245_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBL1520430.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNDIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            4900..5031
                     /gene="ssb"
                     /locus_tag="LP245_002556"
     CDS             4900..5031
                     /gene="ssb"
                     /locus_tag="LP245_002556"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1520431.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            5053..5385
                     /gene="ssb"
                     /locus_tag="LP245_002557"
     CDS             5053..5385
                     /gene="ssb"
                     /locus_tag="LP245_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL1520432.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            5430..5663
                     /locus_tag="LP245_002558"
     CDS             5430..5663
                     /locus_tag="LP245_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520433.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(5822..5944)
                     /locus_tag="LP245_002559"
     CDS             complement(5822..5944)
                     /locus_tag="LP245_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HBL1520434.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            6134..6358
                     /locus_tag="LP245_002560"
     CDS             6134..6358
                     /locus_tag="LP245_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520435.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRKQLVIESMQIRNPDHFTRSMSI"
     gene            6801..7007
                     /locus_tag="LP245_002561"
     CDS             6801..7007
                     /locus_tag="LP245_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBL1520436.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            7007..7258
                     /locus_tag="LP245_002562"
     CDS             7007..7258
                     /locus_tag="LP245_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520437.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEVLLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTKLEN"
     gene            7274..7429
                     /locus_tag="LP245_002563"
     CDS             7274..7429
                     /locus_tag="LP245_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520438.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIE"
     gene            7439..7711
                     /locus_tag="LP245_002564"
     CDS             7439..7711
                     /locus_tag="LP245_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520439.1"
                     /translation="MNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQ
                     ALELTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            8156..8335
                     /locus_tag="LP245_002565"
     CDS             8156..8335
                     /locus_tag="LP245_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520440.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            8394..8750
                     /locus_tag="LP245_002566"
     CDS             8394..8750
                     /locus_tag="LP245_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520441.1"
                     /translation="MLKTKKNSYKLKLSILSIICLLGMIISGHLYRVAYTQFIEYKVH
                     SLGLAGDRYVEYVHYSLKCSSYILLWLIFSLFELLNLIAISSYHLDKLNTKSSRYNEV
                     FKENVKLESDLNKLKK"
BASE COUNT         3485 a         1613 c         1995 g         2608 t
ORIGIN      
        1 gaactaaagc cgaaacatga acggcaaaat tttttagttg gagacgaccg tttagatcat
       61 gcggttgctt ttttatggaa agatccacag acaggagaga cagtaggggc aagttatcaa
      121 ggaacgatcg tcgattttaa tcgtttcggt aaacggggaa cgtataaaca cattgacaag
      181 aatcctacgc caaatcacgg atttaattta aaaataggcg atccgaagca tttaaaattc
      241 tttgaaagta gtattgatct gttaagttac gctgcattga atcgggagaa actacaagat
      301 gcctggttag tttcgatgga cgggttaaaa catcatgtaa tcagtcatta cgttgaagag
      361 tcgatttctg aattaagacg aaaacaaaca tttcctcaat cgattgaaat atgtgtggac
      421 aatgatcgtg caggacatat tttttatgaa aaagaacaga tgaagggaat cgttgatcct
      481 tttaccaata agaaaatccg ttgtgagcga ggaattccaa atgattggca agtacctaaa
      541 gaatacaaag ctacttatga agcagtcgca aaagaaatga gtgttgaacc tgaagcaatt
      601 atggccatac acaaaactga aactaattta cagctgacaa atcaattggt gtctgctcat
      661 gatgttcaat ctacgtttgg aaagatgttg gcgaagggcg aaccagtaga aacaattgat
      721 ttgaaagaag catgtaccac ggtcgcgaag gaactgaaag tatgtgaacg cgcagatgga
      781 acatacaact ttgatcgttt ttatagtaga aaagccaaca taaaagacgt taatgcagga
      841 atccttcttt cctataaagc agaacaatac tacaaaggct ataaaaagca tgaacatgaa
      901 tttgtacctg aagtgaaaaa ggattggaat gatcaattga agcatgagat ccagcaacaa
      961 gaaatcagaa agcaaaaacg tgcgatgttg tttcaacaag gcagacaaca agaaagggag
     1021 tgaagtcgtc actatgaaaa ccgtcatttt agcagaaaaa ccgtcacaag cgaaggctta
     1081 tgccgatagc ttttctaaag ctacccgaaa agatgggtat tttgagatcc aagatcgatt
     1141 gtttacagga gaaactgtga tcacgtatgg ttttggtcat ttagtcgagt tagattcgcc
     1201 cgatatgtac gatgaaaaat ggaaacaatg ggcattagaa catttgccta ttttccccaa
     1261 tcaataccac tatcatgttc ctaaagataa gaaaaagcag tttagtgtcg tcaaacgaca
     1321 gctgcagtca gctgatacga ttgtgatcgc gactgatagc gatcgtgaag gggagctgat
     1381 tgcctggtca atcattcaac aagcaggcgc caatcaagga aaaaccttta aaagactttg
     1441 gatcaactcc ttagaaaaag aagccattta tcagggattc caacagttac gagacgcaga
     1501 agagacctat ccaaaatttg aagaagtaca agcacgtcag atcgccgatt ggttaattgg
     1561 gatgaacggt agcccactgt atagtttact cttgcagcaa aaaggcatac caggaagttt
     1621 ttctttaggt agagtccaaa ccccaacact ctatatgatt tatcaattgc aggaaaagat
     1681 tagaaacttc caaaaagaac catattttga aggaaaagcc caagtaatcg ctcaaaatgg
     1741 cgcatttgat gcgaagcttg atccaaatga aacccaagcg acacaagaag catttgaagc
     1801 ctatttaaaa gaaaaaggtg ttcaattagg aaaacagcca ggtacgatcc ttcaagtcga
     1861 aacagagaaa aaaagtgcgg ctagcccacg tcttttttct ttatcgagcc ttcagtctaa
     1921 aatgaatcaa ctcatgaaag ctagtgccaa agatactttg gaagccatgc aagggttgta
     1981 tgaaggaaaa tatctaagct atccgcgaac ggatacccct tatattacgg aaggggaata
     2041 tgcgtatctg ttggatcact tagacgaata caagcatttt ttaaaagccg aagcgattcc
     2101 gactcctatt catacaccga atagtcggta tgtgaataat aagaaagtcc aggaacatta
     2161 cgcgatcatt cctacaaaaa cggttatgac agcagcggct tttgaacaac taagtccact
     2221 gcagcaggct atttatgaac aagtgttaaa aacaacggtg gccatgtttg cggaaaagta
     2281 tacctatgaa gaaacaacga tcttgacgca agttcagcag cttcagttaa aggcaatcga
     2341 aaaggtgccg ctagatctag gttggaagaa gttatttgga aaagagagcg acggaaaaga
     2401 gaaggaagaa gagccgctac ttcctaaagt gacaaaagga gaaatggtga cggtggatct
     2461 acaagttctt gaaaaagaaa ccaagccacc acaaccttat accgaaggta cgttgatcac
     2521 tgcaatgaaa acagctggga aaaccgtgga tagtgaagaa gcgcaatcca tattgaaaga
     2581 agtggaagga atcggtacag aagcgacacg ggcgaatatt attgaaacct tgaaacaaaa
     2641 ggaatatatc aaggtagaga aaaataagct cgtggtgacg aataaaggga ttttgctttg
     2701 ccaagccgtg gaaaaagagc cgctgcttac gagcgccgaa atgaccgcca aatgggaaag
     2761 ctacttgtta aagatcggtg aacgaaaagg aacacaaacc acttttctag ccaatatcca
     2821 aaaatttgtc tctcacttat tggaagtcgt accagggcaa atccaatcca ctgattttgg
     2881 atcgacgtta caagaagtga aagcagccag tgaaaagcaa gaagccgcgc gtcatttagg
     2941 aatttgtcca aaatgccagg aacaagaagt cttactctat caaaaggtgg cagcttgtac
     3001 gtctgaagcc tgtgatttta aaaggtcaga agggttcatt tgaagcaacg attgttttaa
     3061 aagaagactt cactacaggc tttgaatttt ctgaaaagaa aaaaacgaac ttcaagaaaa
     3121 gaacacgccg cactgcaaaa taatggaggg ttaatcttat gcgtaatacc acacacaaac
     3181 aacaagaaat cgaaaatcaa aaagccaaaa ttcgttcaga acaggaaaaa atgcgtgcca
     3241 gcaaacgaag actgcagcaa ttgaagaacc agcagaggat tcaaaaagaa atcgaattag
     3301 atcgataaaa tcttcctaac tattgtatac gtataaactt atgttatact gtttttataa
     3361 gtttatacgt atacaaagga gggagaaaat gacaaaagca atggtataca agctgctaga
     3421 agaatttaat ggaactttgg ctttgaagga tgccaaaaaa gcgggcattt ctcctgtaac
     3481 gatcaaacgt atggtagatc gaggggagct ggatcgagag tatccaggtt ttttcacctt
     3541 acctggtcaa tttcctgatg aattgtttat ggcgcaaaaa aaatatgaac gcggcattat
     3601 ttcacatatt accgcgttag atttgtatga tttaacagat atgatcccta gacagatcga
     3661 tctgactgta ccttacggtt atcacgtttc tgaaaaagga ttgaaggaat tcgcagttga
     3721 gctacactat acaaaagcgg aatggtatga attaggtaag attgaaataa aaagtcgcta
     3781 tgggaatcct attatagctt atgatccaga aaaaaccttg tgtgacattt ggaatccctg
     3841 gtataacgtt gaggatgaaa tcaaagtaaa agcaatcaaa aactacatgg agtcggacag
     3901 aaaaaatctt agaaaattga atgagtatcg acgaattttg cctacagata aaacgatgcg
     3961 ctcttatatt atggctttaa attaaaggag aatacacatg acacctacgc aattaaaagc
     4021 aaaagtgaag aatatttcta gagaaaaaga agttgatccg cagcttgttt taagacattt
     4081 tatgatggaa aaattcttgg aaaaaatctc agagtctcct tatcgtgaaa attttgtgtt
     4141 aaaaggcggc ttcttaattg gctcaaagta tggcattgaa aatcgaacaa ctaaagacat
     4201 tgatacgact ttacgggaaa tgaaagtaac caaagaaaca ttgacaacgg ttctaaacga
     4261 tattttttca acgccgacga aagaaggcat tcaatttgag attcaaggaa tgaaagaaac
     4321 gagggaagct gattattatc cagggtttag cttacgtgta ctggcacatt tggaaaacat
     4381 gcggccagat tttaaggtag atgttactac aggtgactcg atctatcctg cgacgatcac
     4441 tcacagtcat aaattgatgt ttgaggatcg aacgattcct ttggaatcct atcctacaga
     4501 acaaattatt gctgaaaaat taagtgcaac ctttgatttt ttaacagata attcgagagg
     4561 aaaagatttt tatgatctct atactattcc taaaatggag aagatcgatg agaagacctt
     4621 gaaagatagt gtgagaaata catttacacg tcgaggaaaa actgatccgt taaagatata
     4681 ctatgaaaag gatatggatg tactgaaaaa tagtcacgag ctaaaagata cctggaagaa
     4741 atatcaaaaa agcaatcctt atgctgcgtc gatcacgtac gatgagacaa tggattcgat
     4801 tagtaatttg atggaaaaag tgattcacgt cgaagaaaaa gagcgaaaac tagcttatca
     4861 aagacaccaa cagatgaata gagaaatgga gagataaaga tgattaataa tgtgacatta
     4921 gtaggacgct taaccaaaga tcctgattta cgttataccg caagtggtac tgcagtagcg
     4981 acttttaccc tagccgtcaa ccgaaatttc acgaatcaaa acggcaattg agaagccgat
     5041 tttattaact gcgtgatttg gcgcaaacca gcagaaacaa tggcgacatt agctaaaaaa
     5101 ggtagcttga ttggtgtagt tgggcggatt caaacgcgga cttacgacaa ccagcaagga
     5161 caacgtgtat atgtgactga agttgtagca gataactttc aactattaga aagtaaagca
     5221 gcgacagaga gccgtgcgca cgctgatcaa tcgtccacca gtccaagcac cgccaccttt
     5281 gaacaacgga atacagcgac gcctaacaac aatggattga acgcttcaca gaatccattt
     5341 ggtggacaat caatcgatat tagcgatgat gatctaccgt tttagtttga gaaagaagga
     5401 gtaagcatgg caaaaaaatt agtctgacga tggatctatt gatacccgta attgcattta
     5461 tagacgggat ttctttgggc gtcactgaaa atcctttggt aaatagaatt gcgaaaggat
     5521 cactatttct tgtattcgtg tatcttgtct gttcttatct tttaaaaaga gcaggaaagg
     5581 ataattcctt ttggcgattg actaaagtca cagtagcagc gacagctgtt atacttacgg
     5641 ctattctacc gctttatatg tagagttaac gggaaatcgt tgaacttctt gcgaaatatt
     5701 gctataatga acatgaaaaa gaggagttgc gctaacaacc cctcattaac agcaccgatt
     5761 aaagaacggt ggcagaatat tagttatttg gaaataaccg ctgacctgct aaagtagacg
     5821 gttatttctt tttgtcattt ttaagcatat ttacaatcaa actaatcaaa gcaatggtaa
     5881 acataccaaa accaagaatg gtttgaattg tctcatatgc ggacaaaagg cttactcctt
     5941 tcatagattt tagcacttac attcataagc accaccacct ttccagaagt cgccaccgtc
     6001 ttcaaacttt actgtcttga ctattatagc atatctaaaa tcgaataaaa attctcaatt
     6061 ttagctgttt ttgctataat tttagcgagg tgatcgtgat ggaacaatat attggtttac
     6121 tcgataaatt agggtgatca agacacagcc attgcttgtg cgatttacat tacgcacgag
     6181 tcatgaacca atcaattgtg tagtggccaa tatagaaata gcggataaat tgctgatttt
     6241 ggaagaaggc aagtatacta tttcagtgac aggtcacttc aataaacgaa agcaactagt
     6301 cattgaatca atgcaaatta gaaaccctga tcattttacg cgatcgatga gcatataaaa
     6361 gaagagctgc agtcctaaat gaggattgta gctctttttg ttttacatag aaacagtaaa
     6421 aatgaaaagg cctgtttagg aaggcacaag cgccttctca attgaaagac ctttctctca
     6481 ctccaaccgc caccgccgtt cgagaagaaa ggaagtgaac gctacgcgtt cactaagata
     6541 aagggtcttg catagcaaga caaaatagaa aaaatttcct ctcaccaaaa ggttcgctcc
     6601 tgttcgttat ctctttattg atttgtcaga ccggcaacaa gttgcctttt atcaccaaaa
     6661 agcgacaagg acaagggtaa atggcacgct gcgcgccctt gtcttgtcgc ttttcgttga
     6721 ttcattctgg ccaacaaatc aataaagaaa gaactaacga aaggaagtaa aacctttcct
     6781 aagaggaggc agaatcaatc atgcgaaaga aatttgatta ttggggtgtt cccttcagcg
     6841 aattattccc aaactatcat gcaccacata ctgtcgaatg cgattgtgga gaaagagcga
     6901 aatgtatcaa aagctattgt ttgtatcaat gtccaacatg cgggaaaaaa tataccttgt
     6961 cttatggcga ttatatttta attgatgaga aaggaaagaa acgctgatga aaacacaaca
     7021 caaattattg actgtaaaag aagtcgttca aattttggtg gacaaagaag tcatttctga
     7081 aaaagtagca gaagttttac ttattccgcg gtactggacg atagaaaccc ctttagtaga
     7141 ggatgcaccg actatgctat ttgaagacct agtgaagatt gcaggatatg aactgcatta
     7201 tcaagaaaac ttggaaactt atgaaaacga atattggtta accaaattag agaactaaaa
     7261 aggagaaaaa aatatggctc aaaattacta tgacgaattt gtcaaattac ctttggataa
     7321 aatggcacaa aaaatggagg atatgacgtt cctatacaac gaaacacgtg ttccaaaaaa
     7381 acattataaa gaaaaattgt cggtagctgt ggaagaaatg attgaataag gtgtcgaaat
     7441 gaatcttatt gcgacgtact atcgaacact ggaagaactg aaaaagcaaa atgcaaaatg
     7501 gtttttccaa gccttactat gcttggaagt aggtgtcaaa ccaagcacta ttaaaccttc
     7561 tgaataccaa gctttagaac taacgtatgc gaaatttatc gaaacgaaaa aagccaagac
     7621 tgtttcaagt gaatggttag attattttga aaatatcaat aagtatggcg catattacac
     7681 catgaaaaag gaagacaacg aaaatgaata aggtgattta tcaactaaca acggattcca
     7741 tatcaacgat ttgaaagaaa aaaaggtcaa taatcattta taccgaaaag tgagaatgtg
     7801 tgaaacaagg acaaaaaacg cctagtaact aaggaaatgg ttcttatttc gcaccaatcg
     7861 ctccaaccgc ccccgccgct taggtggtgc gaaataaacg ggcaaagccc gataacttaa
     7921 gagaaagaag gtgatccatt tgaacaagat tattccctta ttgttagtac tgtttgttgg
     7981 cgaaatactt atgcgagata gtgcagctgt acagttaaac ctcgctgtat ttttggtaat
     8041 actggtgttt tgtttgatct tttggcggtt tgtattagtc ctcgtgagtc tactattcaa
     8101 gatgattgca gccatatttt tcatagggtt atttcgatga aaggagtgag taccaatgcc
     8161 aattgcaata ggaaataaac ggttacccgt gacattagat gaaaagagac aaaaagaatt
     8221 gcagcaacta aagcagaagt atggcaaaag tgaatctaag attatgtgta ttgcgttaga
     8281 tctattgatc gcgcaagaaa aagcaggatt tgatgtacca gcgctaaaaa agtgacgtca
     8341 ctttttaatt tgatctatat aagtgatatc acttttacca aggagggaat taaatgttaa
     8401 aaactaaaaa gaattcgtac aaattaaagc ttagtatact atctattatt tgtcttttag
     8461 gcatgataat tagtggtcat ttgtatagag tggcatatac gcagtttatt gagtacaagg
     8521 ttcactcttt aggattagct ggggatcgat acgttgaata tgtccattat tcattaaaat
     8581 gttcttcata tattcttctt tggcttattt tttcattgtt tgaattgcta aatttaatag
     8641 caatatcttc atatcactta gataagctaa ataccaaatc tagccgttat aacgaagtgt
     8701 ttaaggaaaa tgtgaagtta gaaagtgact taaacaagct aaaaaaataa aaagaagaaa
     8761 acataagtta actaaaatta ttttattaag aatgatggaa tataaggata aggttaccaa
     8821 cataacgatc attacttctc tgatatgcta tggacttcta tcaatcagta ttttgtctat
     8881 agattatgga gtaactatac tgcaagcctt agttttggct atgcctatgt atctatcttt
     8941 gtttatcatg catgaaatat ataagctatt tgttttatca aaaaatgtag aaatacgggt
     9001 aaatattttg gtgaatagtt atcaaaaaga actcaaagaa agaagacggt ggcggtattt
     9061 attgaaagga tgaaaaagta ggatttgaca tactggtatt cagaaagtgc cgtcactttt
     9121 aaaacaatgg aaaaggtgga gataagatga agaaaaaaca aactaaacta tcattagcag
     9181 atatttaaca cagttaaccg caactgaaga tggtgttgtt gaatttgaac aatctgaaat
     9241 tgcggtagta gatgatcgtt accttaaaat gccttacttc tttgaccaag caaaggtcat
     9301 ttgcctttgt cactacgatg gggtacgtga ttttaggcgt taaaaagtag tgattatatc
     9361 aactttacga gtaaatataa atttagacat gaaactgaat tatccaatgg aaaatcatgg
     9421 tttataatct agaaaaatta tagtaatgat tggattatat atattctttc gtattttcgt
     9481 acaactgtag cttgtcaaaa ttgagaaatt taaccgatta ggtactttac atcgttattt
     9541 gggtaatttc taaaacatga agcttaccaa cgaataaact gagactatct tattaattga
     9601 tcaatataag aaaatatctt tgaggagatg atgtactatg ttttcgtcta tccacgattg
     9661 gttaggtggt cttttcggcg gtggaggtaa aggtttttaa t
//
LOCUS       DAFEEZ010000088         9387 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000088
VERSION     DAFEEZ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.091"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            2..77
                     /locus_tag="LP245_002567"
     tRNA            2..77
                     /locus_tag="LP245_002567"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            79..149
                     /locus_tag="LP245_002568"
     tRNA            79..149
                     /locus_tag="LP245_002568"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Gly,seq:tcc)
     gene            163..236
                     /locus_tag="LP245_002569"
     tRNA            163..236
                     /locus_tag="LP245_002569"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:197..199,aa:Ile,seq:gat)
     gene            261..348
                     /locus_tag="LP245_002570"
     tRNA            261..348
                     /locus_tag="LP245_002570"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:295..297,aa:Ser,seq:gct)
     gene            370..441
                     /locus_tag="LP245_002571"
     tRNA            370..441
                     /locus_tag="LP245_002571"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:403..405,aa:Glu,seq:ttc)
     gene            464..553
                     /locus_tag="LP245_002572"
     tRNA            464..553
                     /locus_tag="LP245_002572"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:500..502,aa:Ser,seq:tga)
     gene            566..639
                     /locus_tag="LP245_002573"
     tRNA            566..639
                     /locus_tag="LP245_002573"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:600..602,aa:Met,seq:cat)
     gene            658..730
                     /locus_tag="LP245_002574"
     tRNA            658..730
                     /locus_tag="LP245_002574"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:691..693,aa:Asp,seq:gtc)
     gene            734..806
                     /locus_tag="LP245_002575"
     tRNA            734..806
                     /locus_tag="LP245_002575"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:767..769,aa:Phe,seq:gaa)
     gene            811..881
                     /locus_tag="LP245_002576"
     tRNA            811..881
                     /locus_tag="LP245_002576"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:843..845,aa:Gly,seq:tcc)
     gene            894..967
                     /locus_tag="LP245_002577"
     tRNA            894..967
                     /locus_tag="LP245_002577"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:928..930,aa:Ile,seq:gat)
     gene            979..1050
                     /locus_tag="LP245_002578"
     tRNA            979..1050
                     /locus_tag="LP245_002578"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1012..1014,aa:Glu,seq:ttc)
     regulatory      1239..1318
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1316..2509
                     /locus_tag="LP245_002579"
     CDS             1316..2509
                     /locus_tag="LP245_002579"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBL1520442.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            2639..4111
                     /locus_tag="LP245_002580"
     CDS             2639..4111
                     /locus_tag="LP245_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL1520443.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4194..4982
                     /locus_tag="LP245_002581"
     CDS             4194..4982
                     /locus_tag="LP245_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBL1520444.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5049..5717)
                     /locus_tag="LP245_002582"
     CDS             complement(5049..5717)
                     /locus_tag="LP245_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBL1520445.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5832..7544
                     /locus_tag="LP245_002583"
     CDS             5832..7544
                     /locus_tag="LP245_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1520446.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            7547..9319
                     /locus_tag="LP245_002584"
     CDS             7547..9319
                     /locus_tag="LP245_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1520447.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2767 a         1643 c         2121 g         2856 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgccatgc gggtgtagtt tagtggtaaa accacagcct tccaagctgt
      121 tgtcgcgagt tcgattctcg tcacccgctt ttagtttttt atgggcctat agctcagctg
      181 gttagagcgc acgcctgata agcgtgaggt cgatggttcg agtccattta ggcccattag
      241 tacaaaatct tattggtttt ggggaagtac tcaagtggct gaagaggcgc ccctgctaag
      301 ggtgtaggtc gggaaaccgg cgcgagggtt caaatccctc cttctccgtt tcaatatttt
      361 gttttacctg gcccgttggt caagcggtta agacaccgcc ctttcacggc ggtaacacgg
      421 gttcgaatcc cgtacgggtc attaatttaa tatagtttta catggaggat tacccaagtc
      481 cggctgaagg gaacggtctt gaaaaccgtc aggcgggtaa aaccgtgcaa gggttcgaat
      541 cccttatcct cctttttcat attatcgcgg gatggagcag tctggtagct cgtcgggctc
      601 ataacccgaa ggtcgtaggt tcaaatcctg ctcccgcaat taaaaactaa aaacattggt
      661 tccgtggtgt aggggttaac atgcctgcct gtcacgcagg agatcgcggg ttcgattccc
      721 gtcggaaccg tttggctcgg tagctcagtt ggtagagcaa tggattgaag ctccatgtgt
      781 cggcagttcg attctgtccc gcgccattat gcgggtgtag tttagtggta aaaccacagc
      841 cttccaagct gttgtcgcga gttcgattct cgtcacccgc ttttagtttt tatgggccta
      901 tagctcagct ggttagagcg cacgcctgat aagcgtgagg tcgatggttc gagtccattt
      961 aggcccattt attttattgg cccgttggtc aagcggttaa gacaccgccc tttcacggcg
     1021 gtaacacggg ttcgaatccc gtacgggtca tggaagatac tttttgagta tctttttctt
     1081 tttatctgaa agaatgattt taaaaagctt agcagagtta tctttatgga tgattgtgct
     1141 aagctttttt ggacagttct aatgtaaaat atttttatat tttttaagca aaaaaatgaa
     1201 aaaatacgag cagaaaactg ttttatctgc tatacttggt tcgttgcaag ttcccgaaag
     1261 gatccgcagg acggagatgc cttgtaaccg aatttaacta gggggaatca ttataatggt
     1321 agaaagacac ttatttacat cagaatctgt ttctgaagga catccagata aaattgctga
     1381 ccaaatcagt gatgcaatct tggatgcaat tttaaaacaa gatccaacag cacgagtagc
     1441 gtgtgaaacg tctgtaacaa ctggtcttgt tttagtattt ggagaaatat ctacgacggc
     1501 atatgtagat attcaaaaag tcgtacggga aacaataaaa gaaattggtt atacacgtgc
     1561 aaaattcgga tttgatggag atacagcagc tgtattggtt gcgattgatg aacaatctcc
     1621 tgatattgct caaggagttg atgaagcact tgagatccgg gatgaagata aaaaagacgt
     1681 attagatgag attggtgctg gtgaccaagg tttaatgttt gggtttgctg tagatgaaac
     1741 accagaattg atgcctttac caatcgcttt gagtcatcgt ctggtacgac gcttggcaga
     1801 tttgcgtaaa tcaaatgaat taacgtattt acgtccagat gcaaaatctc aagtaacggt
     1861 tgaatatgat gatcaaggac aaccggaacg cgtagataca atcgttattt caacacagca
     1921 tgatgatgca gtagataatg aaacaattcg tcatgatgtc atcgaaaaag tagtgaagga
     1981 agttattcca gctgaattat tagatgatca aacgaaatat tatatcaatc cgactggccg
     2041 atttgtcatt ggtggtcctc aaggggatgc cggattaaca ggaagaaaaa tcattgttga
     2101 tacgtatggc ggttatgctc gtcatggtgg cggtgctttt tctggtaaag atgcgacaaa
     2161 agttgaccgt tctgccagct atgctgcacg ttatattgct aaaaacattg ttgcagcagg
     2221 gcttgctcgc aaagcagaag tacagctagc ttatgcgatt ggtgttgctc aacctgtttc
     2281 gatctcaatc aatactttcg gtactggaac ggttccggaa gaagaactga ttgctgcagt
     2341 gagagaaaac ttcgatcttc ggccagcagg aatcatcgag atgcttgatt tgcgtcgtcc
     2401 gatttacaaa caaacagctg cttacggtca ttttggtcgt acagatgtag atttgccttg
     2461 ggaacatacg gacaaagtag atgcgttgaa agcaagttta gcaaaataag ttatattcag
     2521 ctggaacgat cgccaagtgg tggttgttcc agcttttttt atggcagtta acctcttgaa
     2581 aaagatagta attatttatc tatttttaga tcctgtcata atgaaaggga ggaataagat
     2641 gaaaaaagaa acaaatgtta ctttggtcac agtgagtatt ttcattgcaa cgttcatgac
     2701 ggctattgaa ggtacaatcg taacaaccgc tatgccaacg attgtcggtt cattacatgg
     2761 aatggaaatc atgaactggg tattttcgat ttatttgctg acaaacgcta tgcttactcc
     2821 gatttacgga aaacttgcgg ataaagtggg acggaaacca atctttattt ttgggacatt
     2881 attgtttatt atcggttcgt tattttgcgg tttatctcaa agcatgattg ggttgattgc
     2941 tgctcgtgcg attcaaggga tgggtgctgg ggcaatgatg ccagtagctt tgacgatcat
     3001 cggcgatctt tattctattg aaaagcgagc aaaagtttta ggtttgaata gttcagcctg
     3061 ggggattgcc agtgtttttg gaccgcttgc gggaggattc atcgttgaaa cgatcagctg
     3121 gcactggatc ttttttatca atgtgccgat cggaattcta ttaattattt tgatttggct
     3181 atatttaaat gaaccaaaaa tcatacatga gtctaaacca atggatattt ttggtagttt
     3241 tagtttgatg gccatgcttg tctcattgct gttagggttc caattattag gagacgaagg
     3301 aatgagtccg cttgtttctg ctttgctgct aggtagtatc gtaatgttag gtatttttgt
     3361 ttttgccgaa aaaagagcta aagatcctgt catcatgatg catttattca aaaatccact
     3421 atttgttgtg gtcaacttgg ctgcagcatt ggctagtggt tttttgatgg gaatcgatgt
     3481 ttatatccct atgtggatgc aaggtgtatt agggctgaat gcagcaattg gtgggctggt
     3541 attagcacca ttatcactag tctggatggt cggttctttc cttgcaagca agtggatgac
     3601 tcaaatgaaa actcattggg tcttgagaat tggactacta atcgcagcta ttgggggcgc
     3661 ttggttgtat cttatgcctt tcagaagtaa ctatttatgg ttttttgcta tatcaacggt
     3721 catcggtata ggcttaggtg tgaccatgac tacctcgact gtcagtgcac aaaatagtgt
     3781 atctcgtgac cagcttggtg tagcaacttc ttttaatacg ttagttcgaa caattggtca
     3841 aacagtcatg gtttctattt ttggtttatt gataaatggg gtaactaaac gagaacttgc
     3901 agcagcaaat ttaacaaatg atgcagatat catgaataaa ctggtgaatc cacaaacggc
     3961 taaatatatt gatgcggata ttttgttacc attaagaaaa attctttatg atgggttaca
     4021 ttccgtttat ctagttggct tgttactcgt gatcattgct ttggtcttaa cgcttttcgt
     4081 tcatgaaaaa agtggtaaaa taaaacagta gtttcggtta agatatgtac gtagccgaat
     4141 cattcaaatt taaagttatt caaaaataac ttcttactaa ggaaggcgaa aatatggcat
     4201 ttattcaagc aaatatttat tcgaatgtgt tagaaatgga agtcaatcta aatgtgatac
     4261 taccgcaaac aacaaaaaag gtgattggca ccagttcaga gcaagagaca acggatatac
     4321 ctgttttata tttacttcat ggaatgggtg gcaatcatag tgtatgggaa agacgtacgt
     4381 cgattgaacg ttatgtagca aactacggat tagctgtcat catgccatct actgatcttg
     4441 gctggtacac agatacagtt tatgacatga agtattggac attcattgca gaagagctac
     4501 ctgagatttg tcatgaatta ttcccgcaat taacaagaaa aagagaaaaa acatatgccg
     4561 ctggattatc gatgggcgga tatggcgcgt taaaactagg ccttgcaaaa tcagaaaatt
     4621 tcgcagcagt aatctctctt tcaggcgctg tttctgtagg aaatcgaatg gatgatcttt
     4681 tgatggttcg taaagcatct ttttgggaag ggatctttgg accattggat caaatcgaag
     4741 gttcaaaaaa tgatccgcaa tacttattga aagaactagt aaaaagcgga aaaccagttc
     4801 caagatttta tatggcttgt ggggaatctg attttcttta tcaggcaaat caggaaatgg
     4861 tatctgctat gcaggaacaa ggcttggcgg tcacctttga acaaggacct ggcgatcata
     4921 actggatctt ctgggaccaa tggattcaac gtgcattggc gtggctaatg gaagaaaaat
     4981 aaaaaaagag tcttaaaaag atagctccta tagagatcac aaacatagtg atctctatag
     5041 gagctttttt actgctcgtt ttctcttctt ttattttgtt ggcataagcc ttcaatatag
     5101 gtttgtgcac tcgttagaaa gagtgctttt tcattcaatt ctgcatggga ctgcatactt
     5161 tctttaaatc cctctaattg attttcaact acataattac gcataaatag aactgtttct
     5221 ttcaaaaatt catttccgtc cataattttt tgtcgaagct gctgttcatg ctgctgatcc
     5281 attaactgtc caatcaataa attgtggaga gaggcaatgg cctgatgact ttgggtgact
     5341 gaaaatcctt cacgaacaag taattggatc atttgctcca aatgttctaa tcgactcgga
     5401 aaagcgggca cagtattgat ttctaattct gccccacaag ggaaacgtgt ataaaggtca
     5461 tagtaatttt ccatatactg cagcaactgt tcattccaag gcaaagttgg atctggaagc
     5521 gctaattctt cttccattgt ttcagccatt ttttgcaaga gctgttgttt gtttttgaaa
     5581 taccaatata aagcaggtgc ttgaacatga attctgtttg cgatgtttcg catggaaagc
     5641 tgcgaaagag cttgtgtttc agccaggata tcaaaggcgg cctgaatgat gattgcttga
     5701 gaaagcttta tttccatttt atcaacctcg tgtattgcat tatcttttta aacatggtaa
     5761 attgttagtc ggtctaattt tacagtgtta aattagtcct gtcaatttaa acaaaggggt
     5821 gtaatcaacg aatgaaatta atcttacgac atgcgaaaaa atataaagta gctgttttta
     5881 tttccttgct gtccgtagca gtcatggttg cagcagcatt atggcaacct aagttactac
     5941 agcaagtatt ggaagctatt attacagaag ataatgatga aatgaaaaca attggtattt
     6001 acctgatcag tctggctttg ctaggattag ccgcaggtgt aacgaacacg attttctctg
     6061 caaaagtagc tcaaggcgta agtgcagata tccgagaaga agcatttcga aagatccaga
     6121 cattttcatt tggaaatatc gaacagttct ctgctggaaa tcttgttgtt cgtctaacaa
     6181 atgatatcac gcaaatccaa aatttagtga tgatttcttt gcaatcactt tttcgaattc
     6241 cattcttatt tattggtgcc ttcattttag ctatgatcac gatgccgcaa ttatggtgga
     6301 tcatcgtagc gcttatcgtt acggtatttc tgattacggc actttcattt acaaggatgg
     6361 gcaagcactt catgatcatt caaaaactga ttgatcgtgt gaatagcatt gcaaaagaaa
     6421 acttactagg gattcgtgta gtgaaatctt ttgtacaaga agaaaaccaa ttgaagtcat
     6481 tcagcaaagt aagtgaggac ttaacaaaac acaacatcat agtcggtaca ttattttctg
     6541 tgatgatccc gtccttcatg ctggctgcca atttggctgt ggttggggcg atcttttttg
     6601 tgagcgatct tgttaaagat gatcctacgt taattggtgg aattgcttca ttcatgaact
     6661 acttgatgca gattatgatg gcaatcatta ttggcggaat gatgatgatg atgacttcaa
     6721 gagcagccgt atcgctgaag cggattgcgg aaattttaga tgctgaacca gatcttactt
     6781 atttagacgt tccagaacaa gagttgacgg gttctgtcac ttttgaccat gtttcttttc
     6841 gttatcctgg tgaggataca gatacgctta aagatatcag cttttctatc aaacctggag
     6901 aaatggttgg tatcgtcggg gcgactggtg ccgggaagtc aacactagca caattgatcc
     6961 ctcgtctatt tgatccgaca gaaggcaaag ttgaagtagg tggtgtagat cttcgtcaag
     7021 taaatgaaaa gagtttaaga caaacggttt cctttgtttt gcaaaaagca attttattct
     7081 caggaacgat tgctcaaaac ttgcgccaag ggaaaaagaa tgcaacagaa aaagagatgg
     7141 aacatgcttc ttctattgct caagcaaaag aattcatcga aaagttatct gatcgttacg
     7201 aagcaccaat agaagaacgt agcagtaact tttctggtgg tcaaaagcaa cgtttatcca
     7261 ttactcgtgg cgttatcggt aatccaaaga tcttgatcct agatgacagt acgagtgcac
     7321 tggatgctcg ctctgaaaag ctggtccgag aagcactcga tcgagatttg aagggaacaa
     7381 cgacgattgt catcgcacaa aaaattgctt ctgttgtcaa agcagaccgc atcttagtat
     7441 tggatgaagg cagattagtc ggcgaaggaa cccatgagga attggtagct ggaaaccgtg
     7501 tctatcagga aatctttgaa actcaaaaag gaacggagga gtaagtatga ctgatctaat
     7561 aaaagcaagt aaatttttct atcactattt gaagcggtac aaactctcct ttttctttat
     7621 ctttatcaca gtgatcattg ctacctatct acaagtaaag gcacctcaat acatcgggga
     7681 agcttttcaa gaattagcta attacgtagg aggcttgatg caaggcgtag acgataaaag
     7741 caaatttgtt tctgtaatat ggaaactctt gctgttttat gtactagcta gtgcagccaa
     7801 ctttatctat agtattttgt tcacacaagt agtagggaag tcaacgaacc gaatgcgtat
     7861 cggtctattc aacaaattgg aaaaattgac gatccgtttc tttgattctc atcaagacgg
     7921 tgaaatttta agtcgtttta ccagtgactt agataatatt caaaatagtt tgaaccaagc
     7981 tttgcttcaa gtcatcacga atgctgtttt acttgtcggg atcttgatca tgatgttccg
     8041 ccaaaatgta gagttagctt gggctacaat tgcttccact ccagtagccg ttttgatagc
     8101 tgtcttgatt atccgcaaag cacggaaata tgtggatctt cagcaagatg aagtggggaa
     8161 actaaatggt tatatggatg aaaaaatcag cggacaacgt gtcatcatca caaatggctt
     8221 acaagaagaa acgattgaag gattcttaga gcataatcaa agtgttcgcg aagcaacctt
     8281 caaaggacaa gcttattctg gtctactatt tccgatgatg caaggaatgt cactggtcaa
     8341 tacagcgata gttatctttt tcggcggctg gttagcatta aatggtgatt tggaacgttc
     8401 ggtggcatta ggcttagttg tgacattcgt ccagtattca caacaatatt accaaccact
     8461 gatgcagatt tcatctggat acagcatgat ccaattagcg attacagggg caagacgatt
     8521 gaatgaaata tttgatgaaa aagatgaagt caaaccagaa aacggtaaag catttgatgg
     8581 tgttgaaaaa ggtcttgcgt tgcagcacgt agattttggt tattctccag aaaaactagt
     8641 cttgaaagat gtctcgatca atgtggacaa aggagaaatg gttgctcttg ttggtccaac
     8701 aggatcgggg aaaacgacga tcatgaatct gctaaaccgt ttttacgatg tcaatgatgg
     8761 ttcagtagtc atcgatggaa tagatatccg agattatgat cttgatgcat tacgtagaca
     8821 tgtaggaatc gttttgcaag aatctgtatt gttctccgga acgatcaaag acaatatcac
     8881 attcggcaaa ccggacgctt cagatgaaga agtcatcaat gcagcaaaac aagcgaatat
     8941 tcatgacttc atcatgacgt tagaaaaagg ttatgataca gagatatccg aagaaaataa
     9001 cttattcagt acaggtcaaa agcagttgat cagtattgct cgaacgatca tcacaaatcc
     9061 atctttattg attttggatg aagcaacaag taatgtagac acggtaacag aagcaaggat
     9121 ccaaaaagca atggatgaag caatcaaagg aagaaccagc tttgtgattg ctcaccggct
     9181 gaaaacaatc ttgaatgcag atagaatcgt tgtcttgcgt gatggggaag tcattgaaga
     9241 aggcagtcat catgagttat tagcagaaaa tggattttat gcggaacttt atcataatca
     9301 atttgtattt gaaagttaaa ttaaaagaac ctcgttataa cggggttctt tttatatatt
     9361 ttatgttgtt tgtttttata aggggca
//
LOCUS       DAFEEZ010000089         8968 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000089
VERSION     DAFEEZ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8968
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.092"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(56..349)
                     /locus_tag="LP245_002585"
     CDS             complement(56..349)
                     /locus_tag="LP245_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBL1520448.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(377..1042)
                     /locus_tag="LP245_002586"
     CDS             complement(377..1042)
                     /locus_tag="LP245_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBL1520449.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1182..1814)
                     /locus_tag="LP245_002587"
     CDS             complement(1182..1814)
                     /locus_tag="LP245_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1520450.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1821..2888)
                     /locus_tag="LP245_002588"
     CDS             complement(1821..2888)
                     /locus_tag="LP245_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL1520451.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2885..3616)
                     /locus_tag="LP245_002589"
     CDS             complement(2885..3616)
                     /locus_tag="LP245_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBL1520452.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(3785..4264)
                     /gene="greA"
                     /locus_tag="LP245_002590"
     CDS             complement(3785..4264)
                     /gene="greA"
                     /locus_tag="LP245_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBL1520453.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4400..5575)
                     /gene="mltG"
                     /locus_tag="LP245_002591"
     CDS             complement(4400..5575)
                     /gene="mltG"
                     /locus_tag="LP245_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBL1520454.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            5779..6948
                     /locus_tag="LP245_002592"
     CDS             5779..6948
                     /locus_tag="LP245_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBL1520455.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(7215..8849)
                     /locus_tag="LP245_002593"
     CDS             complement(7215..8849)
                     /locus_tag="LP245_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520456.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTLKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         2855 a         1701 c         1333 g         3079 t
ORIGIN      
        1 atattttcaa aagaaaaaag agaaggtgac aaaaattgtg tcaccctctc tttttttatt
       61 gttttttaaa gtgataggtt ggctcctcca ggttgggatc ataatcaaca agtaaatcat
      121 atcctttaaa gaaccattca tctgcttcct cgataaaaaa aagtgtccca tcaatttcca
      181 ctttctttac aggatgttct ggctgttcaa ctgacattcc aatcgaaaaa ccatcatgaa
      241 cctctgtttt gccgtagact tttccaaaaa aacgtattcc gtaagtttct ggcagatcaa
      301 tttctgagtc aaaccacttt tgtgcttttg gcgttaccgt taatttcatc ccaacaacct
      361 actttctctt ttctttctat tgattcatct tatcgtctag aatatccaca tcgcctgtct
      421 ctccaataac cagtagatta tcattttcac gaacatattc atctgctgca ggagaagcga
      481 taaccgtttg atctactctt cgtatggcga ctactgttaa gtcaaaacgt tgcctgaaat
      541 ttaattcagc taatgttttg ttgaaaaatt taggattgga gactcggatt tctgctaaag
      601 aatatttatc tgacaactct aggtaatcta aaatattctt tgacactaaa ttatgcgcaa
      661 tccttattcc catgtctcgc tcgggatgga cgacgcgatc agctccgatc ttttcaagta
      721 ctctggcatg atactcattt tgggcttttg ctaaaatatt tggtacgccc atttccttta
      781 ccatcagagt aactaagata ctggcttgaa tatcttctcc aatagcgaca attacatgat
      841 cgaaatttct tatgcctaat gatcgaagtg tcatttcatc ctgtgcattt gccacaacag
      901 catgagtggc tatattcata tattcattga cccgatcttc attactatca atagccagta
      961 cttcttgacc agcttcgatc agtgttcggc agatacttcc gccaaatcgt ccaagaccta
     1021 caattgcaaa attttgtttc accgttttcc tcctttagta tcttcttttc tcagtataac
     1081 aaagccttta caaaaacaaa agcaagcatc attattgtaa aaaagccaag aaaaataata
     1141 gttattttct cagcttttga ttatcctctt tatcatcgtt tttatttcac caaaccatgt
     1201 ttgaatgcat agatagcggc ttgtgtacgg tcttccactt ctagcttagc caatatattg
     1261 gaaacatgtg tttttactgt tttcagtgta ataaacaatt cgtccgctat ttcctgatta
     1321 ctttttcctt cagaaatcag cattaaaatt tcattttccc gattcgttag ttcttcatgt
     1381 aatacaggct catttcgccg actcattttt tccatcattt ttgttgtcac ttctggttct
     1441 aatactcgct cgccacgttg cgttgccctt atagcatcag caatttcatg tgcggtagag
     1501 gtcttcaaca aataccctgc tgcacctgct tcaatggcag gataaacttt ttcgtcatca
     1561 ataaaactgg ttacgataat gattttagct tctggccaat cttttaagat tgcttttgtt
     1621 gattcgatac catccatttc ttccatgact aagtccatta aaatgacgtc cggtcgaagt
     1681 gtcatcgcct tctcatagcc ttgtcgtcca ttttcagctt ctccaattac ttcaatgtct
     1741 tcttgaatag ataaataaga agagacgcct aagcgcacca tttcatggtc atctactaat
     1801 aaaactttta tcatccttat ctatgcctcc ttcatcaaag ggaccttgat ttctacactt
     1861 gtaccttgac ctttaaaact aatgattttt actgttccac caataccagc tactcgttct
     1921 ttgatattgt tcaatccata acttcccgtt ttcgtttcat tcatattaaa ccctgttccg
     1981 tcgtcaataa tacgtaacaa aagattattg tctattttgt gcaaatatac ctctaattca
     2041 ttggctttag catgtcttaa tgtatttgat aacaattctt gaacgattcg gaacaagtga
     2101 tcctcaatgg aactagatag ttttacatct tctacatccc atttcagcga aatctggatt
     2161 ttattttgca attccttcaa taactgctcg ataccttgct ttaaactttt ctcttctaaa
     2221 ttgactggac gtagatgaag aagcagcgca cgcatctcag actgggaagc gttgatgatc
     2281 tctgctacca ttttcaactg cttgcgaaac atttctggtg tctcgctttt ttctgcttgc
     2341 tccgtcaatg ccgacatcat catcattgct gcaaacaatt gttgcgaaac tgaatcatgc
     2401 agctcacggg ctaatcgatg tctttctaat tctaaaattt cttctttggt ttgtccatct
     2461 acatattggg gacggctcgt tacaatttgt aattcactag atacttcaat cattttttct
     2521 tttatcttag tgatttcctt atcaatatct ttgatgtata aatcgtccga tgcacttggg
     2581 atcggaagaa gcaacaattt ggattcataa ttgccagaag aaagtgcacg cagcttttct
     2641 tcgattttcc cgtattttgt cttttgaata agtgataata atagaaagac aattaatcct
     2701 acacctaagg aaatggctaa caaatggaag ataagcggaa catataataa acgtgcacgc
     2761 agtaattctc cccaccaatg actttgattg ctggcataaa aataagtgaa aagtgaaaat
     2821 agaataataa ggaaagccgc aatccccgaa taaacagcta gcatcgctct ggatattttt
     2881 cccatcatat tcgtatcacc tcgacatctc caatcaaggt attagtaata atcttcaatc
     2941 tacgagggtt ttcatcataa tcactgctgt agattttgat ttgttcattt ttcaaagaaa
     3001 attgctcttc ttcaaacaag acatttccta ctaatgtcgc atgctctaat cggatggcta
     3061 cgcccaaagg tactaagatc cgtgttctgc ctatcccttt tcttacaatc acaatattat
     3121 catcttttgg caaaagcgta ttgcccaaat ctatgatagt atcaccagaa atgacggcga
     3181 tgttgatatc gtcccattca tagacgtcgt ttccaatacg ttggttaccg aataattgct
     3241 gtcttttccg ctcattatta tgtgttttta attgctctgt ttggatcatc atgatctgtt
     3301 tctttcgcca aaaagcattt ttggttaaat ctatccctga aatctctaca cctttcagac
     3361 caataaataa aacggcaaat acagccatca tccataaagc aggactgttg actaagctaa
     3421 aaaaaatgac caaacttcct aatatcaatt gaaaattttg aaatttagta cgaggatgtt
     3481 tgcgcatagc tagatatata ttgaaaatac cgaatatcac taaaagcaaa agtccagtat
     3541 tgtttacgat ttgccaaaca gcaaataaca gcagtagtgc ttcaactacc acaaaaaaac
     3601 gccaagaact attcatcgct ctttctccct cctgacacat tctcatttca tcatacctat
     3661 ttttttaact gttggctata ggactttaga tgtaagatcg tttgttgaaa tctaaaatac
     3721 acaaagagaa aaagatctag agtgtatcat cagtaagatg aactctctag atctttcagt
     3781 cagactacgc ttgttctact ttgacgattt taactaacat atcgccacct ggagtagcaa
     3841 tagttacttc atcattttta cgtttgccaa tcaatgcttg cgcaatagga gaatcattgg
     3901 aaattttgcc agaaaacgga tctgcttcag cgcttccgac aatcgtgtac tcttcttctt
     3961 ctccatctgg tagttcgatg aatgtaactg ttttaccaat tgatacctca tctgcatcta
     4021 caccgtcgtt atcgatgatt tgagcaaaac gaatcatatt ttcaattgtt gtgattcttc
     4081 cttcaacaaa tgcttgttca tctttcgctg attcatattc agagttttcg gaaagatctc
     4141 cgaaaccgcg ggcaattttg attcgttcaa tgatttctcc gcgtttgact gtttttagtt
     4201 cttctaattc tttttctaat ttttctttac cttctagagt cattggataa actttctcta
     4261 ccatgtgtaa cgtctccttt tttcgataaa ataccgcaaa aggtaatctt ttgaggaata
     4321 tagtccaaaa aagattacca cgcttttctt caaatgtaaa tgtttttcta aaaatgatca
     4381 atgtctagag cctgtttttc taagaattat ttacatattt ttccactaat tccatatgtt
     4441 cttcataagt tttagcgaaa taaacatttc cagtgctcgt atctgctacg aaataataat
     4501 agtcattttc tgctggttct aatactgcct tgattgcctc ttcgcttgga ttgtcaaaag
     4561 gtccaggtcc atagccggta ttggtataca aattatatgg tgaatctaca gctgtatctt
     4621 catacgtcac taattctttg tgttcaccta atgcgtataa aacagagata tctgactgaa
     4681 gtggcatatt tgctttgatt cggttaaaga agacttgtgc aatgttttta cgatcatttt
     4741 cttttacgcc ttctttttca actagagaag ctagagttaa aacttcttgt acagtcaaat
     4801 ttttctgctt gatagctgaa taatagtttt gcatgaccgt attcgtcttg ttcaccattt
     4861 caatcactag atccttaagc gaagtactcg tgtaataatc atatgtggct gggaataagt
     4921 aaccttccaa acggtatttt gtgttctcag ctttagatgc actttccaac agttctggga
     4981 atttttggtg caactcgtta aagaaagtct catcattcac taaatctaaa aattctttct
     5041 tgtctttacc agttaccttc gctacccgtt cagcaatctg atcgatatcg tacccttctg
     5101 gaatggcaat tttcccatct gcaacttttg ttggctcaga agtaccgcct tcttgcaact
     5161 gtttgccaat ctcgtcaaga gtcatattag gcgctaactg ataatagcca gcttgaaagc
     5221 cagttaaatt tttaaatttt gtataataat tgaaaacaat cccgctttta ataatattgt
     5281 ccttctccaa aatctcacca atctgcttgt tagaagagcc actcgggatc tcgacttgga
     5341 ctaattggtc atctgattta tctaaaggct tcaacccgct atctacataa cgatacacgg
     5401 taaatccaag aaatccgcca ataatcaata atgtaagagc aatcactaaa atgatcttcc
     5461 tcacaatctt atcttctttt ttacgcagat ttctccgctt gtcgattata tctgctgtag
     5521 ctgccttact ggcttctttt ttatctttac ttgggtgttg tttgtttcct gacaaaacaa
     5581 ctcctcctta ctatcaagtt cgtaacttta ttcattatac atgatatttg aattggcgtg
     5641 aatgatttta tttaaatatt ctatcaaaaa tgtaagtagt aaatccatta ctataagatt
     5701 aaaataaatg ttatcaagat acaagctatt ttagctttat tctttctgta aaaaagaaag
     5761 gagactaaat aaactattat gaaaaaagga aaacatgcta aaaaaagaaa atattcattt
     5821 ttaatgatcg ttgtcgtgtt gtttagcctt agtgcgttct ctacaggaac tattcttgga
     5881 tggcaatttt acaataatga acactctcag atagttgccc atgctcaatc agctcaaaaa
     5941 aagttgatac tgactaccaa tgaacaacag ctcgttgaaa aaatcgatca actattaaga
     6001 aaaaatgatt atattggctc aatttacgta aagaaaaata atcgcatcat catggaaaaa
     6061 ggctatggct atgcgaataa actcacgcaa caaccaaatg atccttctct ttattatcag
     6121 attggttcgg ttcaaaaagc attgactact cttttgattt taaaacaagt cgagcgtggg
     6181 cacctttctt tagatactaa gctggctcaa ttctatccac aaattgctgg cagccagcaa
     6241 attactatcc gtgacttgct gtatatgcgc tcaggcttgc accgaactgc ttctccaacc
     6301 ataccgatga ctgatgaaga agtcgttcaa tttgcgattc agcacttaaa atttacagat
     6361 tatcagacct ctcattatga ttcattgaac tttaccatat tgactggaat tttgatcaaa
     6421 ttaacaaatc aaccgtatga aaaattattg accgatgata tcatcgaacc tttaggatta
     6481 cagcatacaa aattttatga ccaagtcaaa aattcatcca atcatgcact atcctatcaa
     6541 atgtctaaag aggatgatta ctttaaacca ctgacagaat ctgaaacaga gatccataac
     6601 gaattaggga ctggtaatat cagtatgtcc gtctatgatt taaatacgct gtttacacaa
     6661 gttttatctg gaaaactagt ttccaaagac ttactcttct cattatggcg tgaaaatgcg
     6721 aatggacatc catatagtgg tggggtatat agcggagata attatatcct gtcgcaagga
     6781 aatatcgact cttttgatac atctgctata tttagcaaag attcacagga tgctatcatc
     6841 atggaaagca atataaaagc tgacaaaact atcaaactgc ctactgctga tctaagaaac
     6901 caaatctatg acctgatgga aggaactact aagttggcaa atagctgata tgatgaaaag
     6961 atagcaaata ctacttcttt gaatagcatt tgcttaaaaa aagtactcga ctaaacgtag
     7021 gaaagagtgt gggacaaatc taaaaatcaa tttttgctac agactttaat tccaaataaa
     7081 cagaacagaa agaggtgttc ttctttctgt tctgtccaaa ttattctaag atttctcttt
     7141 accaacatta tttgacaaag ggcctattaa atctaaaata gtatctttag attgctaaaa
     7201 tatgtgctag caaatcattc atggcttgtt cttattttta attttatgca ataaaaaaga
     7261 agaacaatta gcgtgattat agaaataaat aatgagattt tagaaaaaaa tgtgtatgaa
     7321 tacctgattg ttactttatt tattccactt tcacttttta ctgtaacaaa aggacctcct
     7381 tgttttagta ctgtagcatt ttttgaatta acagtaaccg ttaatccttt ataccggaat
     7441 acaggtaaaa ctattgtttt gccttttgaa gatttaagcg taaatgtaat ttcatcttta
     7501 tttggagaaa agctactata aataacttga ccatcttctg taacttgatg gtttttcaaa
     7561 agcaattgat cttttttata gcctataggt acataatcaa aattctcaaa ttcttcaagt
     7621 ttattttcca tttgttcatt agaataagtt ccttgaaaat tcatttcttt caccatgtta
     7681 actactgatg aataatttaa aattgaaata gctaatatta ataatagtat aaaatttctt
     7741 ctccttgtat aagaaaattt ttccaactgt ggagaaataa atagagatac tgaaaaagat
     7801 atgaacaatg ttgaaaatat cataaaacgc caaggagctt gaataatatt taaaggagta
     7861 ttttgtaagg caaaccatgg aaatattttt gtacaaagta gaatagatat tatacccatt
     7921 atataagtga ttttagataa gattcctaat tttttaaagt taaatgttag tataattaaa
     7981 caaataagca aagttaagcc aataccaaat gatagtaatt ctgaatctat acttccaatc
     8041 aaaaactctt tacccagata aattgctctt ttttgtaata tatccacata aggtctattc
     8101 agatcttgat acaatgtctg ctcaatcata ggacctataa acgctagtga aagaagtaaa
     8161 gtaactatag cagcttttat taatttaata attaagaaga tttctatttt ctttttccga
     8221 taaaattgaa taattaaagc aattataatc attaccatag tcatagctac agaaagaaca
     8281 tgagtgtaaa ttaataaagt catgctaatc gccaacataa cccaagattc tttttttgag
     8341 tcgtaaagct ttataaaccc gagtaaaata agaggaagta ttgacattgc gagtaattcc
     8401 cccattgccc ctcgaagaaa tatttctaca ctcctaaaag aagatgttgt atatataata
     8461 gcgaaaaagg agctagtaac atgttttttg gtaatttcat acattacata atgacatata
     8521 aatagagtaa tgagcgtaac aatataaaga aaaaggttat agcctattgc taaattagta
     8581 aacttgatca ataaaaataa aggatataga gttaaccatg ggtaaaaatt atttacttgc
     8641 atgccatatg atctaaacgt ttcaaaatta ataggggagc taaaaataga ttctaaactt
     8701 aacgcacgat taatgtgaaa tgccgtatca taaaagccaa atatttccat gtttttaaat
     8761 gctggaaata aatataataa actaacaaat gcataaacta taaatatttt tacagaaaaa
     8821 atttttttca aattcatata ccacctcatg tttttttata ttacatatag tatcatttat
     8881 ttttttaaaa cactagatta gtcactatat aaaatgtgat taattttatt attaataaaa
     8941 tattttttat attacaaaag tagtgttt
//
LOCUS       DAFEEZ010000090         8694 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000090
VERSION     DAFEEZ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.094"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(430..960)
                     /locus_tag="LP245_002594"
     CDS             complement(430..960)
                     /locus_tag="LP245_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1520457.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(1142..1798)
                     /locus_tag="LP245_002595"
     CDS             complement(1142..1798)
                     /locus_tag="LP245_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBL1520458.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(1925..2398)
                     /gene="dfrF"
                     /locus_tag="LP245_002596"
     CDS             complement(1925..2398)
                     /gene="dfrF"
                     /locus_tag="LP245_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBL1520459.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(2817..3035)
                     /locus_tag="LP245_002597"
                     /pseudo
     CDS             complement(2817..3035)
                     /locus_tag="LP245_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3066..4280)
                     /locus_tag="LP245_002598"
     CDS             complement(3066..4280)
                     /locus_tag="LP245_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBL1520460.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(4621..4863)
                     /locus_tag="LP245_002599"
     CDS             complement(4621..4863)
                     /locus_tag="LP245_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL1520461.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(4895..5452)
                     /locus_tag="LP245_002600"
     CDS             complement(4895..5452)
                     /locus_tag="LP245_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL1520462.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(5465..5653)
                     /locus_tag="LP245_002601"
     CDS             complement(5465..5653)
                     /locus_tag="LP245_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBL1520463.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(5666..6232)
                     /gene="amaP"
                     /locus_tag="LP245_002602"
     CDS             complement(5666..6232)
                     /gene="amaP"
                     /locus_tag="LP245_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBL1520464.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            6649..6822
                     /locus_tag="LP245_002603"
     CDS             6649..6822
                     /locus_tag="LP245_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520465.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            7462..7935
                     /locus_tag="LP245_002604"
     CDS             7462..7935
                     /locus_tag="LP245_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBL1520466.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            7944..8171
                     /locus_tag="LP245_002605"
     CDS             7944..8171
                     /locus_tag="LP245_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1520467.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT         2652 a         1714 c         1287 g         3041 t
ORIGIN      
        1 tccaaccgta aatctttcac accatcagtg ataaacactg agctgacagc aattacgaca
       61 actaccataa ttgcctgcac ttaaatttct gcaaaagaaa acgacaatca atttcttatt
      121 ttttgaaatc aactgtcttt ctcatattta ctattcaatt ttcatagtga tataggtaca
      181 atttatatca ctactgtaaa aatggggttt tgccttataa atacagcgtt ttccgcttgt
      241 tagtgtatag tgtttcttgt tttttgtgcc ccccttgtta gataacgggg gctttgaacg
      301 gctcgcaagc tcgccgaacc gccgaagcga accgccccct tgcaagcatg gcggaaaaat
      361 cttaaggatt ttcccgccaa cgtggtcgga tcgctccgtc ggtttaacag cttttctgtt
      421 tctctctagt tatctacgca tataaatcaa atcggttatt ccgttataag tctgtgtttt
      481 acaaagcctt aactttattt ccctgtctat gttgcccaaa agacgaaccc catttcctaa
      541 cagagtagga ataacagaaa tgtaatattt atcaatcata tttttgctta ccaactgctg
      601 aacaagattt gctccgccac aaatccaaat atcctttcct gcttcttgtt ttagccgttc
      661 caataataaa acaggatttt cacttgtaaa atgaatttgt tgggaagaat tgcactcttt
      721 atgtgttaat acataagttg taaatttatt atatacccat tcttgcggag aaagttcagt
      781 aacaacctga tgagaagtat tccaccccat taagacagta tctatatctt tggtaaattc
      841 tgtataagtg tcgatgtttt cattgtcatt tccatgacca tttagccaag ctactccacc
      901 attaccgtcc gcaatatatc cgtcaaggct catggcaata aataaaacta cttttctcat
      961 tttttctctt ttataaatac aaacaggaat ttatttctct tttttactca taagggaaca
     1021 actgattgct acaaataaac ccattaaaat ccatggaaat gctgctctta taaaatcact
     1081 aaccatactt tattcctcct taaattccaa tttccttagt tctacaaact gaaatttttg
     1141 cctatgaatg tatcttgttc tttatacgca aacaggcttc tgtgtgcata atccaatgtc
     1201 ttgaaaacgg catttgaatt agtccacaaa tatctttatt acaccaataa tcaatcagcc
     1261 aaattgcttt ttcattgtcg tttactacat tcaacgattc taagtatcct tttctttctt
     1321 tcggtatttt tcttttcaat tcatcataag ataaccgttc aagcattttc tcagtgcttt
     1381 cccatacttc gaaaatatat aaatataatt cttccagatt aagctgtttt gaaaagtctg
     1441 caatctgctg tttcatgagt tcatttcctg ttgtaatgat aggtgaattg atacgctctt
     1501 gataattgcc tgcaaaaaat acttgttcat cttcatttat cactgtatgc acaactatat
     1561 cttcaatgcg gaaaatatgc caaatagaat aagcaatcgt cttactatga taaccatcag
     1621 cgtttatgaa ggggattgag ttaaaatctt ctctgcataa ttcttctttg aaagatacta
     1681 aggtttgtat taactgactt cgtaaagtaa gtaaagtatc aatacccctc ttataagtat
     1741 ctttcttttt tatttgtgcc tgcattgttt tattaagttc agaccattcc ttattcatat
     1801 tcaatcctct ctcaaattct gattttatcg ccccatacaa actggaattt gtcttacaac
     1861 aatttatata tgcataaaaa gcaatatatt tatgaaaaca ccctaaatcc aaaatttact
     1921 caattcattt tttccttaca taaaatgttc tcgtatattt cacttcctca ccaagtgttt
     1981 cccctatcaa aacttcaaaa tcattgatat caaattctgg aaagaatgta tctccatctt
     2041 caatatttaa atctacttct gtgatataca ttttatctac tatttgcaaa gcttccttaa
     2101 atagtccata tccaccagat atgtatacat ctcgtccttt agccaataat aatgcatctt
     2161 ctaatgattt aactgaaact aaattatctc cttgatactc tgttgtggtg gaaacaacaa
     2221 tattcattct attaggcaac ggatgaccga tttcttcata agactttcgc cccataataa
     2281 ccacattacc cgttgttaac tctctaaatt gcttttgttc tccctttatt ttccatggta
     2341 tattaccatt cttgcctata acattattct ttgacctcgc aacaatcaaa cctatcatct
     2401 atttcatcct ccataatatg atgtcgtacc tgtgattcca tcaagtgcac cacatcttaa
     2461 caaactcaaa attatctcga actaaccagc tcgacaaatt ccttttttgt cttcatctgc
     2521 attatatcat attgttataa gcattgccat ttcttttctg cttttgaaaa gttacttatc
     2581 agcctatgtt ttgtaaaggg tgatattcag catttctcac gcaacaagcc cttgacaaac
     2641 catagactaa taagttttaa ggtaatcaag cagaaatgaa atagtctgct gtttcacggc
     2701 aacaaaaaag agataccaac acacttatgt agtatctctt agtctagtag caatattctt
     2761 ttgtttgcaa gcaggtaaac atgggctgtt tcttaatatc tttttgtttg ggaaacacct
     2821 ttttcccatc ctttcaccgt tgccatctct gctgcgcaca atgccacagg gataaaccat
     2881 agcaaaccgc ctaataacaa gaaaaatact aagctgaagc ctgaggtcgc gaatgtggga
     2941 tattcatata atgaaacgac cattgagatg gtcatagcca aaaagccaaa gaacgttaat
     3001 ttttttgcag gaattttcgt tttgctttgt tgcatgaatc ttcctctttt ctatttgaat
     3061 ttgtttcaat tgagtttgtt gccaaagaag aaaaagtcca atccttcttc ttgttcttct
     3121 tttgtagtag tgatcgttgt aaagtgcatc gccgatttta aaatcactgt tgtcagcaca
     3181 taggcataca cggcagtaat gatgacacca atcacttgaa tccctaagaa gtaccagctg
     3241 cttggattcg ttagtaaatg gctgttagat gcaaagatcc ctatcagaat cgtacctgtg
     3301 aatccgccca tgccatgaac accccacaca tcaagtgcat catcccattg tttcttttta
     3361 cgaaaatcaa cagcagcatg acagacgata cccgcaatga tcccaatcag catggcactt
     3421 tttgcttcta cataaccggc acaaggcgta atggctgcca atccagcaac ggatcctgtt
     3481 agtacgtcga caaaatcaaa gccatttcct tttacttttg caatgatcag ccaagtaatc
     3541 atcgcaaatg caagagcgat gaatgttgaa ccaaatgcat tgactgcttg ttcatctgct
     3601 cgaagtgcac caccggaatt aaaaccgaac cagccaaacc aaagcagtcc tgtaccgata
     3661 gcagctgcca taagactgct atgctgactt ctttctccta aaggaatctt tctttgacca
     3721 agtgtgagga tacatgctaa agagccgaat ccagctgtcg tgtggatgac tgctccacca
     3781 gcgaaatctc taaatcccat ctgatccaaa aatccgccac cccatatcca gtggcaaaca
     3841 gggaaataaa tcagcagatt ccaaaaaata acaagtataa tatagccttt taaattcaat
     3901 ctccctgcaa aagctcctgt catcaaagga acggtaatca cgataaacat cagttggtaa
     3961 agaaagaaca ttaaaaatgg aatcgttgca ccatgaaaca tgttggggaa gcttgtaaca
     4021 tgtctcatca aaaagaaatc tgccgggttt ccaataacac cgccgatatc ccgtccaaag
     4081 gccaatccga atccaccaaa tacccacata atcgttgtta tcccaacgga gagaaaagat
     4141 tgagacatga tcgttagtat attattcttc cgtgctaatc cgccgtaaaa aaaagctaga
     4201 ccaggagtca tcaggcaaac cattgctgta cataaaatca tgaatgctgt atctcctgta
     4261 ttgataggta atgtattcat ttttttcgcc tcctttctac gattacgagt ataaaagaag
     4321 gtgtagttgt ttttttcttc tgtttttttg aattaatact tgcatttata aaagacagac
     4381 aattaataaa agcttgatgt gttgtgctct ttttcgtttt tcacacaaat aaagacaaaa
     4441 aataaacggt cttcttttta tagaaaaccg tttattttcg tcttttttta tttttaaaga
     4501 tattttttca taaggaataa agaatacttc atataaaata tataaaaaag aaccgcagcg
     4561 agtgtcgcta cggttctcaa atttgttctt catttcaaca taagtttttc ttcaatttgc
     4621 ttataattta cgtgcaaaga atgaaacgac taatactaaa atgattgcac cgatcaatga
     4681 tggaatgata gccattcctg caattgttgg tccccaagtt cctagtaaag cttgtccaat
     4741 tgctgaacct actaaaccag caatgatgtt tgcgatgatc cccattgatg atcctttatt
     4801 cgtgattgct cctgcaattg ctccaatgat accgccgacg attaatgccc aaataaatcc
     4861 cattttaaat tcctcctaac tgacttctta cttcttattg tacacgtggt tcgttatttt
     4921 ctttgacttt ttgtgcacct ttgcctacag cagattttgc tttatctgtt tggcgtgaag
     4981 caaattgtcc tgtggatttt gctgcttctg ttactttgtc ttgtactgtt tcttgatctt
     5041 tttggtattc ttcttgtgtt ttgatgtctg caacattcac attcacttcg ataacatcta
     5101 aatgtgtcat attgtttact tcagtactga tcaattcttt gatttggttg taaatatctt
     5161 cgatgtcttt accgtattct acgatcacat ctagatccac agctacttgt ttcttaccta
     5221 cttctgtatt gatacctgct gttacgttat ctgtgttgac taatttttca gccatatttg
     5281 agaaaaatcc gccatctaat gtcaatagac catctacatc tttcaatgca taaccgatga
     5341 ttttttggat gactttgtct tcataagtca attcaccatt catcatgcgg ttttctcctt
     5401 tttcatttgc caaaactgat ccatttgttg tattcatgtt tttgttttcc atctttgttt
     5461 cctcctatga tttaaaaaat tgatcaacta ttcctgactg tttcaaataa aaaccgattc
     5521 ctgcgccaat tgctgtcatg attatgatca acaatgtctt gaaaaatcca atcgttaacc
     5581 ataaaacagc tagcagtagt ccaagacccc caaagataat agggagcttg tatgctgaaa
     5641 atagttcttt cattatttgg ccctcctatt ccactcgaga gtgcttgtag tctcttgtat
     5701 cttcttgttc ttcataaccg ctgtatgtga ctgccacttt gaccgtttct tttgttccga
     5761 gtactttagt tacttcttct tcgatatctt gcatcaatac acctgttttc cctactaatg
     5821 aagaagttcg tttcaagtct ccgttgacat ggatatggat tcgatttttc gttgaacgta
     5881 tccgtacttt aggtgaatga atgaactctt cttcgtgtaa atgggaacgt accaaccctt
     5941 cgatcgcttt tttgtcgatt gttagtttgc catcttcccg tttcataacg aaagttcctc
     6001 ttgactttgg atagaaaaga acgactagca agatgataat agcaagaacg gcaaatacta
     6061 cagctgccca gaaaatatat tgttgcatgt agtaattcgt taaagtaaag aagcgaaatc
     6121 gttccaattg ttcaggcata atatacggcg cattgatcaa cgcaatcgct agaaatactg
     6181 aaagtagcag taaactcatg ataacaccga ttatttttaa ccccttattc attttccacc
     6241 tcctataaac ttatttttac cctgtaaata actctaccga caatcacagt atagatagcg
     6301 aacagttagc atagcatcag taaataaagc gctaccaaac attgctggat cataacggcg
     6361 ttttattgcc agtctgatac tgaaataaca attgcttact tattctctat ttacttttga
     6421 ttgctggcta tacttaaagg atattattca agattaaaaa ttgcaaagat tatgctcagt
     6481 tattattaca agattctatt tatttattaa attttttcgg agaattaaaa aatacaataa
     6541 ataactttag ttactttaat gcgttcttac tttattttta tattatcatt tttcttattc
     6601 acttctttgg tttatactat tcttataaat aaaaacgagg tatgtcctat gatgaaaaga
     6661 ttgtactatt cattgatcat aacgattggc tatttgattg tatcaaatct aggaaatatg
     6721 gtatttggta tcagtaaaga attcagttgg actactacat tatgggaatc tctattcttt
     6781 ttcatcttcg tatttttgtt acaaaattat cgaaaaaaat aaacatgtgc catctatctg
     6841 ttggcacatg ttttaggatt tatggtactt tttattcggc aatccatttt atttttctac
     6901 ttcttcttaa tacctctaac acttttgatt tataaactaa tccaatgcat ctacttgcgc
     6961 ttattaagct atttcagcta gatagtacca ccccatgcgt caatgcttga ttttcctttt
     7021 gtataacatt gtataagcaa taaaggacaa ataagtggtg attacaccaa accattgaat
     7081 aagaaaaatt ctgatacgta aataaacatg aacttgaaaa aattaatgaa tcggttagct
     7141 actacgtagt tgtctttttt ctcatacagt tctgttaact tacacttctc ttcgctagat
     7201 aataaaaaat cctccaactg tattgtccaa tataatccca ggcatctaaa ctagcattat
     7261 agaagagaca cacatagaat ctaaaataac tggttttaaa tgtttcttac aatcaaaaaa
     7321 agctgttaaa tgcactccac accttcatac tctatcattt tttataaacg atatattttt
     7381 attgtttttc gataaaaaat agttgtttta caataattat tctgctatat tttagctatc
     7441 aaagataaaa gagggataaa aatgaaattt aaaacattgc tattaaaatt tgtcgtttta
     7501 ggtataagtg ccgtatttat tttgttcggc gtactttttt atactcagat cgctacaagc
     7561 gaaaaaggat tcaattttga ttggcagacc acattatttg tttctgtcat ttactttgcc
     7621 cttctcctag ggatcgttat tgcttatttc ttattgaaac tattgaaaaa aatcgaagat
     7681 aaccaagctt tttccactca aagcttaaac atactaaaaa aaatcgaacg aaccattttg
     7741 tttattggtt tcgccttttt tggcttactt cctaaattta tgaaagtagc ggatttagac
     7801 gatgctccag gtttgatgtt ggtaggaatc gctgtcgtat tcattccttt tgcagtatac
     7861 acattaacaa gcgtgctgga aaaactgctt gaacatgcga ttttacttaa gacagatcat
     7921 gatttgacag tgtgaggtgc gacatggcaa ttatcgttaa tttagatgta gtattagctc
     7981 aaaaaaaaat gagtgtgact gaattgagtg agaaagtggg cattacgatg gcaaacatct
     8041 ctattctaaa aaatggaaaa gcaaaagcca tccgtttttc cactctcgaa aaaatctgcc
     8101 aagttttgga gtgtcaacca ggtgatttgt tgacctataa aaatgactcg aatactatac
     8161 cagaagaata aaataaagta gaacaaacag taaataaaaa ataatctgaa tgatagatgt
     8221 gtgagacttt tagaagttat ttacgtctat tattcagatt ttttatttcg attgaatacc
     8281 gttttatcta taaataagat atgtactgac tcatacaaag ggggcctttt cttctccatg
     8341 tactatcact tttcctgata caactggttt cctgttacgt tgtagttgga tctgctttta
     8401 gtataatact ttattcattc caccagactg atagcagttt gagcagtcta aataatcatg
     8461 tagtattaca ggccattctg tttcatacct tgaagtgctt aaaacttcag ctaatggccc
     8521 attgtgttaa ctcttactcc attctttttt agtaagctcc catatatact gtaaagcctt
     8581 ctatatatta tgtcatgttg ctttttaaca tttactatgt agttttgata aaatgatttg
     8641 aataacagtg atggacaatt cttttttatt tttaacatta ttttgataat aatg
//
LOCUS       DAFEEZ010000091         8660 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000091
VERSION     DAFEEZ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.095"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(177..734)
                     /gene="frr"
                     /locus_tag="LP245_002606"
     CDS             complement(177..734)
                     /gene="frr"
                     /locus_tag="LP245_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBL1520468.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(737..1459)
                     /locus_tag="LP245_002607"
     CDS             complement(737..1459)
                     /locus_tag="LP245_002607"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBL1520469.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1595..2476)
                     /locus_tag="LP245_002608"
     CDS             complement(1595..2476)
                     /locus_tag="LP245_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBL1520470.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2575..3357)
                     /gene="rpsB"
                     /locus_tag="LP245_002609"
     CDS             complement(2575..3357)
                     /gene="rpsB"
                     /locus_tag="LP245_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBL1520471.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3716..4195
                     /locus_tag="LP245_002610"
     CDS             3716..4195
                     /locus_tag="LP245_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBL1520472.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4412..5503
                     /gene="phnW"
                     /locus_tag="LP245_002611"
     CDS             4412..5503
                     /gene="phnW"
                     /locus_tag="LP245_002611"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBL1520473.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5496..5624
                     /locus_tag="LP245_002612"
     CDS             5496..5624
                     /locus_tag="LP245_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBL1520474.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGTQLTDKEIR"
     gene            5628..6173
                     /locus_tag="LP245_002613"
     CDS             5628..6173
                     /locus_tag="LP245_002613"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBL1520475.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6627..8318)
                     /locus_tag="LP245_002614"
     CDS             complement(6627..8318)
                     /locus_tag="LP245_002614"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBL1520476.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
BASE COUNT         2410 a         1771 c         1568 g         2911 t
ORIGIN      
        1 taaaagattc ccactatctt aagtattata gcaatatcta actgtttttc ctatgaaatc
       61 attgtttttt tatttaaaaa ctgaataatt ttttcttttt ttaattttta aataaaagaa
      121 atataaataa aaacagagga agcggaatga tccgcccctc tgtttttatg attttattaa
      181 acttccaata attctttttc tttatcagca gcgatcttat ctacttcttt gatgctgtta
      241 tctgtcaatg tttgtacgtc tttttctaat ccgcgcaaat catcttcggt aatatcacca
      301 tttttttgtt gttttttata ttcatcgatc gcatcacgac ggatgttacg aatcgcgatt
      361 tttgcatttt ctgcttcttt tttcacatct ttagctaatt cttttctgcg ttcttctgtc
      421 agttgcggga taactaagcg aatgacattt ccatcattgg ttggactgat tccgatatca
      481 cttgccataa tagctttttc aacatcttga agaatgctct tgtcaaaagg tgtgatcatt
      541 aaaacacgtg cttctggaat ttggattgat gccatttggt tcaatggtgt tggcgcaccg
      601 tagtagttca cagtaatacg gtccaaaagg ctagcgttcg cacggcctgc gcggatttgc
      661 ccaagttcac gttgaagatt ttgtgctgct tttttcattt tttcttttgc ttctgtcata
      721 attgcatctg ccatttttat ttccccctta cagttgttcc gatattttcg cctaagattg
      781 cacggcgaat atttccgtgt tcatttaaat tgaagacaag cagtggaata tcattatcca
      841 tgcttagtga acttgcagtt gaatccatga cttgtaatcc tttggcaata acttccagat
      901 gagtcagttc ttcaaatttt actgcatttg catctacttt cggatcagca gaataaacac
      961 cgtctacatt gtttttagcc atcaggataa catctgcgcc gatttctgcc gcgcgtaatg
     1021 ctgctgttgt gtctgtcgag aagtacgggt tgccggtacc gcctgcaaag ataacgatcc
     1081 gtcctttttc taaatgacgt tctgctttac ggcgaatata tggctctgcg atttgacgca
     1141 tttcaatcga agtttgcacg cgtgtcggta cacccacgtt ttccaacgta tcctgtaaag
     1201 ctaaggcatt cataactgta gctaacatac ccatgtaatc agcttgagca cgttccatgc
     1261 ccatttgtgc tccgatttgt ccgcgccaga tatttccgcc gcccacaacg attgccattt
     1321 caacgcccag ctcgtgaact tctttgattt cttggatgat ttctttgatt actggtggtt
     1381 tgattccaaa tcctgcgtcc ccagctaaag cttctccact caattttaag actacacgct
     1441 gatatttcgg tgtgaccatg ttcattcctc caatattttc tattgccatt ttaccatact
     1501 tagatgattt cgacactcta agactggttt ttcttgtttt gcttaaaaaa agggagcgca
     1561 caaaccgtgc gttcccgtct gttattcaac agaattattt tttcacttgg ctcataactt
     1621 cttctacaaa gttatcttcg cgtttttcga taccttcgcc aacttcgaaa cgtacgaatg
     1681 ttttaacagt tgcgcctttt gatgcaacgt atttttcaac agtcatatca ggatctttaa
     1741 cgaatggttg gtccaccaaa gcgatttctg ctttgaattt cttcaagcgt ccttctacca
     1801 ttttttcaac gatattcgct ggtttgcctt cgttcaatgc ttgttctgta agaacagttt
     1861 tttcatgttc taattcagct tctggaattt gtgattcgtt tacataacga ggattgatag
     1921 ctgctacgtg catagctacg tctcttgcaa ctgtttcgtc agttgttcca tctagaacag
     1981 tcaatacggc aatacgtccg cccatatgca agtatccacc aaatgcagca ttgtcgtctt
     2041 tttctacaac ttcaaagcga cggaagctga ttttttctcc gataacttga gttgcttcga
     2101 tcaagtcaga ttcaattgta cctttatctg ttttgatttt cattgcagct tccatgtctg
     2161 ctggtttgtt ttcagcaaca agttctgcaa tttcttttac taaatcttgg aacatttcgt
     2221 ttttagaaac aaagtctgtt tctgagttta cttcaacgat tgctgcagtg ttacctttca
     2281 cagcaactga agccaatcct tcagctgcaa tgcggtcatt tttcttcgca gcctttgcca
     2341 ttcctttttc acgtaaaaga tcaactgctt tttccatgtc gccttctact tcaactaatg
     2401 cttttttcgc atccatcatt cctacgccag tcatttcgcg tagttctttt accattttag
     2461 ctgtaacgtc tgccatgttt aactcctcct gtgtgttttt ctttttaaaa aaagctgctt
     2521 caaaggagag tgaggcttgt cgcccagcct ttgaaacagc tccatcattc aaaattattc
     2581 tgctgaagaa ttgtcgcctt caacaacatc tacgatttct tcgattgatg ttgctgtgtt
     2641 ttcttctgtg aaatcttctt caactacttg atcttcacct tggtttcctt cgatgaaagc
     2701 atcagccatt tttgaagtaa tcaatttaac ggcacgaatt gcatcgtcgt ttgaagggat
     2761 tactacgtcg atttcatctg gatcgcagtt tgtatcaacc atagctacga ttgggatatt
     2821 taatttgtgt gcttcttgaa cagcaatacg ttctttacgt gggtcaacga tgtacattac
     2881 atctgggatt cttggcatat cagcgatacc gcctaagaat ttttcaagac gttcacgttc
     2941 tttgttcaaa ccagcaactt cttttttagg tagaacttca aaagttccat cttcttccat
     3001 tgcattgatt tgtttcaaac ggctgatacg tttttggata gtatcccagt ttgtcaatgt
     3061 tccgcctaac caacgatggt taacgaagta ttgtcctgca cgagttgctt cttctttgat
     3121 tgcttcttgt gcttgttttt ttgtacctac gaataatgct acgccgcctt cttcagcaac
     3181 gctcttcatg taatcataag ctgcatctac taatttaact gttttttgca agtcaatgat
     3241 gtagattccg tttctttctg tgaagatata tttcttcatt tttggattcc agcgacgagt
     3301 ttggtgacca aagtgtacgc cggcttctag taattgtttc atagaaatta ctgccatgtt
     3361 tgtttcctcc gatttggttt tatttttcct cttcttatct tctaccttgc cggcaaactt
     3421 tttcaagcac ctaccgacaa tccaataaga atgtggattt gctgatgcat aaagcaccct
     3481 cagctattat acagacaaaa gatccgtatc gcaagagcaa atatactttt ctgctcaaca
     3541 ttcaatagtt tacctgaaag ataaaaagaa ttcaagaaaa acagtagatt tctctttgtt
     3601 tctttattat cctttttcca taaaataatt ttaggtataa aagacgaata ttattgggca
     3661 atccttcttt tttttgttat gatacatgtg aaatctttcg taaaggagaa agaaaatgcg
     3721 caaagctcaa agacatttgc tgattaaaca agtcattgaa gaattcccga tccgtacgca
     3781 agaagaacta ttaaacaaac ttgggcatta tggcgttacc gccacgcagg caacgatttc
     3841 tcgagatatc cgtgatctaa aaatcgtgaa ggcacctgat gaaaatggcg tttcccgctt
     3901 cgtattgttt cgcgaaaaag gaactcctga gactaggact gaggaagagg atcggctggt
     3961 tcaaatgatt gaagacattg tattgaaagt cgaacgagtc cactttttga cgatcgtcaa
     4021 taccttgcca gacaatgctc atttatttgc atctgtttta gatgagatca aacctccctc
     4081 tattgtcagt acaattgctg gattcgatac gatcatggtc atctcggaaa atgaggagga
     4141 cgcaaaacga gtagaagaat ttcttcacca tccaactgaa gtatcacttt tttaatcaga
     4201 gcacgtattc ctaatatgga atgcgtgttt ttttattttc aatattttcc ttattgaata
     4261 aacctttaca ctctttacaa aaatacatca ttttttattc aaatttttca acaccttgat
     4321 tgaatcacaa taatcatcat ttatattgga tgttaacaag agcagcttct tgctctttgt
     4381 gtatttcaaa aaagaaatga aaggaaatca tatgtataaa ttattaactt ctggaccatt
     4441 gacgacttct gaaacagtga aaaatgctat gctgatcgat cattgtactt gggatcaaga
     4501 atacaaagaa attacacaat ggataagaaa aaaattattg gatcttgctc aagtatcgga
     4561 aggaatatac acaacggtct taatgcaagg tagcagctcc ttcggggtag aatcggtatt
     4621 aagttctgtg atcaggccag aagatactgt actgatttgt tcaaacggcg catatagaca
     4681 acgaatgatc aacatgtgcg aatgtctgaa actgaactat accgtttatg aggtatcgga
     4741 acatcaaatc ctccaagctc atgtgattac acagctgatt gaagagaatc cgtctatctc
     4801 cgcactagca atggtccata gcgagactac ttccggtatt ttgaataatt tggaagagat
     4861 tgctgctgtc acacaagaaa gagatctttt gtttatagtg gacgcgatgt caagctttgg
     4921 tgggataccg atttgtgtag ccgaactagg gattgatttt ttgatttcca gctcaaacaa
     4981 atgtattcaa ggtgttccag gcttttcttt tgtacttgct aataaagcgg aactggaaaa
     5041 acgaaaaaat gttagccgaa gtttgtcact tgatctatat gaccagtacc gcgtgatgga
     5101 aaacgagaat ggcaaatggc gtttcacttc ccctacccat acggttttgg cttttcaaca
     5161 agcgctgaag gaactagagg cagaaggagg aatcgaaact cgatattcac gttatctcgc
     5221 caataatcat gtgctacgac aaaaaatgac agagatgggg ttccagcctt tcattcaaga
     5281 atatcagggg ccattcatca cctcttttct ttaccctaag gactggcgat ttgattttaa
     5341 tcatttttat cagtatttaa agcaaaatgg atttgtgatc tatcccggga aaatcagcga
     5401 tcatgaatgt tttcgtatcg gaaatattgg cgagatctat ccggaagata ttttggaact
     5461 gacagcaatt atcaaagact ataaggagaa cgttaatgat taaaactgta atttttgatt
     5521 gggcaggaac aactgtggac tttggctgta tggctcctgt ccacgctttt agaaatgctt
     5581 ttctagaaaa aggaacccaa ctgactgaca aagaaatccg ctaaccgatg ggaaaattaa
     5641 aatgggatca tatccaacag cttctttccc tcccttctgt caaaaaacaa tggatagcta
     5701 tttatggaca actacctcag gaaaaagagg tggaggaatt gtatcaacaa tttgaacatt
     5761 atctgtttaa agatttggtc aagcattcta ccttgaaacc cgacacattg gaaacgatcg
     5821 aacggttgag aaacgctggg atcaatattg gttccacgaa tggatttaat gctcctatga
     5881 tgacaatcgt agcagaaacc gcaaaaaaag aaaggtattc accagacttc atggcaactt
     5941 ttgaagacgt cgaagggtat ggtcgaccgt ttccttatat gatccataaa aacatgcagt
     6001 acttcaaaaa caagtcggtt gatgaagtaa tcaaagtcgg agatacggtc tcagatatcc
     6061 aggaagggaa aaatgccgga gtgttgacag taggtgtaat tgaaggtagt tcgctaatgg
     6121 ggatttctta tgatgagtac caaaaattag agatggggaa aaagatcgtt taaaacagtc
     6181 tgttgctctt agattccaac aagccggcgc tgatatttgt gtaaacaatt taaaagagtt
     6241 aacagaatac attttgtacg ctgacaagaa tccagaatga cttttataca aaataagagg
     6301 ttgtgaaaaa gctgtcctgt atcaagtaat aaaaacagcc aagcaaaaat agctcctcat
     6361 atttttcgtt tggttaggct tattaccgca gatgcaagct tttgaacacc gtttattcga
     6421 aaaaaaaaag ggagctgtga cacgactttt gtcacagtcc ccttatttgc aaacaaacag
     6481 tgtttaagag acaacctctc cactaaacgg tgttcattca gctgactctc ggtatttgct
     6541 caaaaaacga taaaatttga aaagctattt tctcttttgt ttctctaata ctcggatcag
     6601 aacgctgatt tcacattctc tttttcttac atcttatctg gtgcatgaag tcctagcaaa
     6661 cgaaggtctt ctttcaataa tacagtcact gcataaacta gagctaagcg tgcttctttt
     6721 tgttcatcat cagctaaaat cttcgtatga gcatagtatt tgttgaatgc ttgtgctaat
     6781 ttgattgcat gtttcgcaat cactgacggt tcgtattttt ccccagcaga caagaccgtt
     6841 tcagggtatt tttgaactaa tttaaccact tcccagctgg tatcgtcatt caatgcatag
     6901 tctgctgttt ctgaagggac aaatcctgct ttttccaaca ggctgactgc acgagcatgt
     6961 gtatattgca cataaggtcc agtttctcct tcaaatcgaa caacttcttc caggttaaag
     7021 tcaaatgtat tcagtcgatc gtttttcaaa tcgtggaaaa tgactgcccc aaccccaact
     7081 tgtttagcta cagcatcttt gttttccaaa tcagggtttt tctcgctgat ttgttcttta
     7141 gcagattgga ttgcttcatt taatacttct tctaataaga cgatctttcc tttacgagtt
     7201 gataattttt taccaccttg cgtgatcaaa ccaaatggaa tatggtgcat gtcgtcagac
     7261 cagtcaaagc ccatttcctt caagacagct ttcaactgtt taaaatgata gctttgttca
     7321 ttccctacta catatagaga ttgtttgaag tcgtaagtac gtttacggta caatgcagca
     7381 gctaagtcac gtgtaatgta tagtgtcgca ccgtctgact tcttaatcaa cgctggattc
     7441 aggtcataag cagataggtc aacgatctct gcacctttat cctcgttcag caaatgtttt
     7501 tcttctaaaa gtttgacgat ttcatccatc ttgtcattgt agaaagcttc accgttcaac
     7561 gaatcgaaac gtacttccag cagatcatag attttattga attctttcat cgattcatca
     7621 cggaaccatt gccataattg aatagcctct ttatcgcctt cttccagacg tttgaaccaa
     7681 gcacgagctt cttcatttaa ttctggttct gtttcagcta cttcatggaa ttggacgtat
     7741 aaacgaagca attcattgat tggttctgct ttaacagctt cttctgtacc ccattttttg
     7801 taagcgacga tcagttttcc aaactgtgtt ccccagtcac ctaaatggtt gatgcggatt
     7861 ggctgataac cgattttttc cataatgaaa ccgatcgaat taccgataac tgtcgaacgc
     7921 aaatgtccca ttgagattgg tttggcaata ttaggagaag acatgtcgat tggtactgtt
     7981 ccttgattcc cgatgttgct atccccataa tgttcttttt ctttcactac tgtttgcaaa
     8041 acttttttgc tgataagttc tttattcatg aaaaagttca agtaaggtcc gacaacttcg
     8101 attttttcaa agttggcaga atcgattttt tctgctaaat ctgcagcgat ttgctgtggc
     8161 gcttttcggt aaacttttgc taatgaaaag gctggaaatg caacatctcc gtgttcagct
     8221 gattttggat tttctagtaa ttgctcgact tgttccagtg ttaaatcatc tttgacagcg
     8281 tcatagacag cttttgcgac aagatcttta ttattcatct ttattcctcc taaagtgttc
     8341 ccttgattgt taaacaaaaa aaatctctag cgacggcata cttagtatgc catcactaga
     8401 gacgagattt cccgcggtac cactccaatt gtcctaaaaa aggaccagct ccatctgata
     8461 tcggtagacg accgtctgtt taaaacagaa ttctccaagt gcgcttcgtt gtatcttctt
     8521 cattcggctt ccaccacttc cgaattcgct agccaagaat gatacaagta ctctcttgtt
     8581 caacaaatct tagtcttatt aaactttctt gaattatatc agaaaaaaaa acgaaaggct
     8641 agtcgtttca taaaaaaaaa
//
LOCUS       DAFEEZ010000092         8490 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000092
VERSION     DAFEEZ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.096"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..173)
                     /locus_tag="LP245_002615"
     CDS             complement(<1..173)
                     /locus_tag="LP245_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL1520477.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="LP245_002616"
     CDS             complement(593..1714)
                     /locus_tag="LP245_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HBL1520478.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVMDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYKPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="LP245_002617"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="LP245_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBL1520479.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="LP245_002618"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="LP245_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBL1520480.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="LP245_002619"
     CDS             complement(4304..5215)
                     /locus_tag="LP245_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1520481.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="LP245_002620"
     CDS             complement(5232..6239)
                     /locus_tag="LP245_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL1520482.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="LP245_002621"
     CDS             complement(6236..8365)
                     /locus_tag="LP245_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL1520483.1"
                     /translation="MKKKLFRIVGIVFISIVLLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..>8490)
                     /locus_tag="LP245_002622"
     CDS             complement(8370..>8490)
                     /locus_tag="LP245_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1520484.1"
                     /translation="GQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2600 a         1726 c         1485 g         2679 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtttgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccatca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca ataggacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg
//
LOCUS       DAFEEZ010000093         8298 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000093
VERSION     DAFEEZ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8298
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.097"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            47..679
                     /locus_tag="LP245_002623"
     CDS             47..679
                     /locus_tag="LP245_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBL1520485.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(681..1586)
                     /locus_tag="LP245_002624"
     CDS             complement(681..1586)
                     /locus_tag="LP245_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL1520486.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(1671..2330)
                     /locus_tag="LP245_002625"
     CDS             complement(1671..2330)
                     /locus_tag="LP245_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL1520487.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     CVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            2646..3590
                     /gene="mvk"
                     /locus_tag="LP245_002626"
     CDS             2646..3590
                     /gene="mvk"
                     /locus_tag="LP245_002626"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBL1520488.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            3583..4560
                     /gene="mvaD"
                     /locus_tag="LP245_002627"
     CDS             3583..4560
                     /gene="mvaD"
                     /locus_tag="LP245_002627"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBL1520489.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            4573..5658
                     /locus_tag="LP245_002628"
     CDS             4573..5658
                     /locus_tag="LP245_002628"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBL1520490.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            5655..6719
                     /locus_tag="LP245_002629"
     CDS             5655..6719
                     /locus_tag="LP245_002629"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBL1520491.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(6968..7771)
                     /locus_tag="LP245_002630"
     CDS             complement(6968..7771)
                     /locus_tag="LP245_002630"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBL1520492.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(7791..8096)
                     /gene="kduI"
                     /locus_tag="LP245_002631"
                     /pseudo
     CDS             complement(7791..8096)
                     /gene="kduI"
                     /locus_tag="LP245_002631"
                     /inference="COORDINATES: protein motif:HMM:NF002091.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
     gene            complement(8078..>8298)
                     /locus_tag="LP245_002632"
     CDS             complement(8078..>8298)
                     /locus_tag="LP245_002632"
                     /inference="COORDINATES: protein motif:HMM:NF018513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HBL1520493.1"
                     /translation="ALGIMLVAFIVAKKNKYPVVEKGQMAHAGKIIKEAIPSLLLIVI
                     IIGGILTGIFTAVEASAIAVIYKWVIRF"
BASE COUNT         2505 a         1740 c         1625 g         2428 t
ORIGIN      
        1 gattcccgct tctttgctat actaaagaaa aacgaggtga acccacatga aaaaaatcga
       61 acctattcca ccttctcttc ctcttcttac aaagggagag ttttatttag aagatgagga
      121 gatcttctct ggtcttctga tcaacggagg taaccaaagc tatctcgatg ccaaaaatat
      181 ggtattaaga gagagtcata tccaaaaact tacgatgcaa aaaacaggtt tacgtcattt
      241 tgaatgcagt aatgtcattt ttgaaaaatg tgatttttcc aatctggagt ggattggtgg
      301 cagtttccac caagtcgtgt ttcatcaatg taaattaaca ggtacgaatt ttgccgaaag
      361 ttatcttcga gactgtactt tcactgattg tattgcttcg atggcttcct ttagtagtac
      421 aaacttgaaa gctgtctcct tcgatcattg tcaattagaa gacagcgaat tttatgaggt
      481 cacttggaaa aacctttttt tgtctgacaa tcagttaacc ggttcgaact ggtttcgaac
      541 ttctctgaag ggattagact ttacgactaa tttcttcaca acaatcgctt tatctcaaga
      601 ttctttggcg ggactaatcg tcaatcaaga gcaagcactt gtgatcgccc aagcccttgg
      661 tttgcagatc aaagactaga tcaacgaatc cgccgccaca gtgcaataag catccaaata
      721 gataagacca aactgatgat caaggcgatt tcccatccga aaacggaatg ggtaaagggt
      781 aactggagat tcattccgaa gaatcctgtc acaatagttg gaacggtcaa gatcagcgac
      841 cagaccgtca aaaatttcat cgtgtcattc aagttgttat tcagcaaatt attataagtg
      901 ccagagagct ggtctaaaat ctgcgaagct aagttcgtca tttcaactgc ttgtcgtgct
      961 tcgatcagtg catcgtccaa ctcttctttt tccttttctg acaacttgcg ataaatagcc
     1021 agtgccttga tttgttctaa aagtactaca ttttgttttg ttcctgtaac taagtaaacc
     1081 aaaccgatct ctaaatctga aagttgcagc agattcttgt tcgttgtttt ttctcttaat
     1141 ttcagattaa gccgctgacg ttcactattc acttcctcga ttaaaggaaa aaaggaatca
     1201 gaaatcaaaa acaatgtacg aaacaataaa ctgtatacac tcatgtctgg catccgttcc
     1261 aaaagcgatc gaattagtcg aatcacgtac tcggtattcg gcgtggtaaa tgtaaacaaa
     1321 ccgtcttctt ttaaaataaa agcgatagga ctagtttcat aatgattatc gactttttgc
     1381 tggtgcggaa catttgatac aagcagtaac gcttcatcaa aagaatcgta ctctacgcgc
     1441 gcccgttcat ttttatctag agaataagtc agcatctcgt cactaatgcc atattcttct
     1501 tttaagtttt taacagctag cacatcgttt tgctgtacat tgatccaaaa attacggtct
     1561 tgattaaaat agtgtttttc ccgcatactc tatcctcctg acatttgttt ccagtataaa
     1621 gaaaaaagtc gctcaaataa aggtttaccc tttatttgag caactgtaaa tcaaatggat
     1681 actttggttt ggcgaatctc tgctaatttt tcttcgatca ttttcaagac ttcttctttt
     1741 gcttgaggat cttccacaaa attatagcgg tctccatcga tttggatttt tggactttct
     1801 ttgtattctt cataccattg atcataacgt ctgttcaatt ctttgtaata atcgtataga
     1861 cttgggtcaa aggacaattg ttcatacgaa cgaccacgtt tttcgatacg ctctaacatc
     1921 gtatcaaaag atacacgaat atgaactaat aaatccggat gttttttatg ggcagcatag
     1981 ggaagttctt ccatcatgtt ttccagcagt tcatcataca cacaaacttc tgtttctgtt
     2041 gctcttccta gatctgcatt tagatggaaa agcagtgaat cttcataaat cgaacggtcc
     2101 aatacattat tgtcatcttt cattgcttgt ttgatgcttg caaaacgttt attcaaaaaa
     2161 taaatttgca gcaaaaaagc atactgttca gggtttgcat aaaataaggg caagacttca
     2221 ttatcatcaa tcgattcata aaatgcctga ctatcaaagt gttcagccat catttctgtt
     2281 aaacttgatt ttccggcacc aattgtacct gctaaaacga tcacgctcat ttacctccag
     2341 ctcacttcat cactaaatat tgtgtttaac tccaaccttt tttaaatata cccccaatat
     2401 ctagtagtgt caattgtatt ttttctagtc aaagaagaaa aaaagtcaaa aaattcttaa
     2461 gaaaaaagtg ttttttcttt agaaaacgta ttcttagttt tacttctgag atggttttag
     2521 taaaataaag gaggaatgtt ttttgagacc cttagtggac aaaaaaattc gtgaagcagc
     2581 gcaactcgtt ttgggcgctt tattttttgc ttaaaaatca cttttacgtg agaaggagtt
     2641 agattatggc aaactatggc caaggagaat caagcggaaa gatcatattg atgggcgagc
     2701 acgcggttgt ttatggagaa ccagcgattg cctttccttt ctatgcaaca aaagtcaccg
     2761 cattccttga agagctggat gcaatggacg atcaactggt ttcttcctac tattcaggaa
     2821 atttagccga agctcctcat gcattaaaaa atatcaaaaa attattcatt cacttaaaaa
     2881 aacagcatga catccaaaaa aacttgcaac tgaccattga aagcacgatt cctgctgaac
     2941 gtggaatggg atcaagcgct gcagtcgcca cagcagtcac tcgtgctttt tatgattact
     3001 tagcatttcc tttgtctcgt gaaatactat tagaaaatgt ccagctttcg gaaaaaatcg
     3061 cccacggtaa tcctagtgga atcgatgcag ccgctactag cagcttgcag ccgatttatt
     3121 ttacaaaagg gcatcctttt gactactttt ctttgaacat cgatgctttt ttgattgtcg
     3181 ctgatacagg aatcaaagga caaacaagag aagccgtcaa agatgtcgct cacctctttg
     3241 aaacccagcc tcatgaaact ggacaaatga tccaaaaatt aggatacttg acgaagcaag
     3301 caaaacaagc aatcattgag aattcaccag aaacgttggc acagacaatg gatgaatcac
     3361 agtcacttct ggaaaagctg acaatcagca atgattttct taatctattg atccaaacag
     3421 caaaagatac cggggcattg ggtgccaaat taactggcgg tggacgcggt ggctgtatga
     3481 ttgcattagc acaaacaaaa acaaaagccc aagaaatcag tcaagcactt gaagatgcgg
     3541 gtgctgctga aacttggata caaggattag gagtacatac ctatgtttaa aggcaaagca
     3601 cgcgcatata ccaacattgc tctaatcaaa tattggggta agaaaaatga agaactcatc
     3661 cttccaatga acaacagcct ttcgttaaca ttggatgcat tttatacaga gacagaagtc
     3721 atcttttctg atagctatat ggtagatgaa ttttatctag atggcacctt acaagacgaa
     3781 aaagcaacaa aaaaagtcag tcagtttctt gacctttttc gtaaagaagc cggcctctca
     3841 ctaaaagctt cagtaatcag tcagaatttc gttcctaccg cagctggatt agcctcctct
     3901 gccagcgggc tagctgcttt agcaggagct tgcaatactg ctcttaagct tggattagac
     3961 gatctctctc tttcaagatt tgctcgacgc gggtctggtt cagcttgccg aagtattttc
     4021 ggtggtttcg ttgaatggga aaaaggccat gacgacttaa gttcttacgc taagccagtc
     4081 ccttccgatt ctttcgaaga cgatttagca atggttttcg ttttgatcaa cgaccagaaa
     4141 aaagaagtgt ccagcagaaa tgggatgcgt cgaacagtcg aaacatccag tttttatcaa
     4201 ggctggttag attccgttga aggggatcta tatcaattga aacaagcaat caaaacaaaa
     4261 gatttccaac ttctcggaga aacgatggaa agaaacggac taaaaatgca tggaacgact
     4321 ttagctgccc agcctccatt cacttactgg tctcctgaca gcttaaaagc gatggatgcg
     4381 gtgcggcaat tgagaaaaaa aggcattcca tgctacttta cgatggatgc tggccctaat
     4441 gtcaaagttt tagtggaaaa cagccattta tctgaggtac aagaaacatt taccaaatta
     4501 tttagcaaag aacaagtaat tactgcccat gctggtccag gaattgcgat tattgaataa
     4561 agggagattt ttatgattga agtatctgca ccaggcaaac tctatattgc cggagaatat
     4621 gcagttgttg aaacaggaca tccagcagtt atcgctgcag tcgatcaatt cgtaacagtc
     4681 actgtagaat ccgcacgaaa agtcggaagt atccaatctg cacaatatag tgggatgcct
     4741 gtacgttgga caagacgcaa cggagaatta gttttagata ttcgggaaaa tccttttcat
     4801 tatatccttg ctgctattcg tttgactgaa aagtatgcac aagaaaaaaa cattctttta
     4861 tccttttatg atctgaaagt aacaagtgag ttagacagtt caaatggccg gaaatatgga
     4921 ttgggttcta gcggtgccgt gaccgttgca acggtcaaag ccttgaatgt tttttacgcg
     4981 ttgaatttat ctcaattgga gattttcaag attgcagcac tagccaattt agcagttcaa
     5041 gataatggtt cctgcggcga catcgctgct agctgttatg gtggctggat cgctttctca
     5101 accttcgacc atccttggct ccaagaacaa gaaactcagc attctatcag tgagttactt
     5161 gccctggatt ggccaggtct atccattgag ccattgattg ctcctgaaga tttacgttta
     5221 ttgattggtt ggacgggtag ccctgcctct acttctgatt tggtcgatca agttcaccgt
     5281 tcgagagaag acaaaatggt ggcttatcag cttttcttaa aaaacagtac agaatgtgtc
     5341 aacgaaatga tcaaagggtt taaagaaaat aatgtaacgt tgatccaaca gatgattcga
     5401 aaaaaccgac aattactgca tgatttatct gcaatcactg gggtcgtcat cgaaacgcct
     5461 gctttgaaca aattgtgtaa tttagctgaa cagtatgaag gagccgcaaa atcttctggt
     5521 gcaggtggtg gcgattgcgg aatcgtaatt gttgaccaga aatctggcat ccttccttta
     5581 atgagtgcat gggaaaaagc agaaatcact ccactgccgt tacatgtcta tagcgatcaa
     5641 agaaaggaaa accgatgaat cgaaaagacg aacatgtttc actagctaaa gcctttcatg
     5701 ataaacaaaa aaacgaattt gacttcgtac ggatcatcca taaccctttg ccgcaaatag
     5761 cagtttctga tgtcgatcta agtacacagg cagttgggtt tacactaagc agcccatttt
     5821 atatcaatgc gatgactggc ggaagcgaaa aaacaaaaaa aatcaaccaa gatcttgcaa
     5881 tcgtcgcaag agaagcagat ttgatgattg ccactggttc agtcagcgct gccttgaaag
     5941 acccttcttt agccgatact tatacgatta tgcgacaaga atatcctcac gggaaaatca
     6001 ttgccaacat cggtgcaggg acttctgtcg aaagagccca agaagctatc cgattgtttc
     6061 acgcagatgc cttacagatt catttgaatg cacctcaaga gttggttatg cctgagggag
     6121 accgtgattt taccaattgg aaagtactta ttcaagagac tcaaacagcc attgacgtcc
     6181 ccctcatcgt aaaagaagtc ggttttggca tgacaagaga aacgctcaat gatctagctg
     6241 ctttaggagt tcatacagtt gatatcagcg gtcgaagcgg aacaagcttc acccagatcg
     6301 aaaacgcccg tcgctccaag cgggaactga gttatttagc tgactggggg caatcgacag
     6361 tctcttcatt gcttgaagca aatgaagcag acacttctat ggaaatccta gcctccggag
     6421 gtatccgcaa tgcctatgac atatttaaag ccctttgtct cggcgcaaat gcagtgggta
     6481 cttcaggaac cgtactgacg catctgatga atcacggcgt agaagaaact attatactga
     6541 tgaagcaatg gcaagaagag cttcgtctgc tttatactat ggtcggcgca acgaataccg
     6601 cggccctaca ccaacaatca ctgatctttt ccggaccagt gaaggattgg tgcgaagcaa
     6661 gagggatcga cttagtgaag tatggaagac gcacagaaaa gagcgtggga caaaagtaaa
     6721 gaacactttt atcccacgct ctaaacacgt ataaacggcg gaagcaaaag caactccttc
     6781 ggaaataagc tgaaattcac aaaaatttga aaagcaattt tcgtgaattc cttcttattt
     6841 cttggagtta aacgcttctg tcccagcctc ttttttcgaa taaatgatgt ttaatcagct
     6901 gtccttcggt attcgttcaa gccgctgatt tcacaacctc tccactaaac ggtgtactaa
     6961 agctctttta aggttgtttt ccgatatagg caagtatgcc tccgtccaca tacaagacat
     7021 ggccgttaac gaaatcagat gcgctagaag ccaagaagac agatggtcca gccaaatcga
     7081 ttggctcgcc ccagcgtgct gctggcgtac gtccaacgat aaattgatcg aatggatgac
     7141 gttcaccgtt ttcttgtgtt tcgcgtaatg gagcagtttg cggtgtagca atataacctg
     7201 gtccaattcc attacattgg atattgtatt gaccgtattc agaagcgatg tttttcgtca
     7261 gcatttttaa tccgcctttt gccgcagcat aagcactgac cgtttcgcgt cctaattcac
     7321 tcatcatgga gcagatattg atgattttac cgccgccttt ttcgatcata tcccgaataa
     7381 ctgcttttga aacgatgaat ggggcattta aatccacgtc gattacttgg cggaagtctg
     7441 ccgcatccat ttcgatcatc ggtgtccgtt tgatgatccc tgcattgttg actagaatat
     7501 caactgaacc tacatcttct ttgatctgtt gaaccatcgc ttgaaccgct tcttcatcgg
     7561 tcacatcgca gacataacct tttgcatcga tgcctgcttc tttataatgc gctatacctt
     7621 catcaactga ttcttgattc aagttattaa atacgatttt tgctcctgct gtagctaaag
     7681 agcgtgcaat ctcaaatcca ataccataga cagcaccggt gactaatgct acttttccat
     7741 ctaaacgaaa catatccata ctaaattcca tcattttctc tcccttatgc ttattttaat
     7801 tgatccattt gcaccatatc catgtctgta taggtgatat tttctccgca cattgcccag
     7861 atgaatgagt aattgcttgt acctacacct gaatggatcg accagcttgg cgaaataatg
     7921 gcttgttcat tgtctacgac taaatgtttt gtttcatctg gtttgcccat catatggaac
     7981 acacgtgtat cttcattggc ataatcaaaa tagacataag cttccatacg acgttcatgt
     8041 gtatgacaag gcatcgtatt ccaagcactt cctggttcta aaatcgtata acccatttat
     8101 aaatgacagc tatcgctgaa gcttctactg ctgtaaatat ccccgtcaag ataccaccga
     8161 taatgatgac aatcaataga aggctaggaa tcgcctcttt tattattttt ccagcatgag
     8221 ccatctgtcc tttttcgaca acagggtatt tattcttttt agcaacgatg aatgctacta
     8281 gcatgattcc tagcgccc
//
LOCUS       DAFEEZ010000094         8238 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.098, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000094
VERSION     DAFEEZ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8238
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.098"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(561..1601)
                     /locus_tag="LP245_002633"
     CDS             complement(561..1601)
                     /locus_tag="LP245_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL1520494.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1950..2276)
                     /locus_tag="LP245_002634"
     CDS             complement(1950..2276)
                     /locus_tag="LP245_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520495.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2263..3066)
                     /locus_tag="LP245_002635"
     CDS             complement(2263..3066)
                     /locus_tag="LP245_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL1520496.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3419..3709)
                     /locus_tag="LP245_002636"
     CDS             complement(3419..3709)
                     /locus_tag="LP245_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBL1520497.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3845..4024)
                     /locus_tag="LP245_002637"
     CDS             complement(3845..4024)
                     /locus_tag="LP245_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520498.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4021..4371)
                     /locus_tag="LP245_002638"
     CDS             complement(4021..4371)
                     /locus_tag="LP245_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520499.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4364..5689)
                     /locus_tag="LP245_002639"
     CDS             complement(4364..5689)
                     /locus_tag="LP245_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBL1520500.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            complement(5858..6442)
                     /locus_tag="LP245_002640"
     CDS             complement(5858..6442)
                     /locus_tag="LP245_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1520501.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            complement(6653..6856)
                     /locus_tag="LP245_002641"
     CDS             complement(6653..6856)
                     /locus_tag="LP245_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520502.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            complement(6866..7288)
                     /locus_tag="LP245_002642"
     CDS             complement(6866..7288)
                     /locus_tag="LP245_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520503.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            7602..8216
                     /locus_tag="LP245_002643"
     CDS             7602..8216
                     /locus_tag="LP245_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1520504.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIITSVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
BASE COUNT         2543 a         1487 c         1228 g         2980 t
ORIGIN      
        1 tccgttgcgg gtaataccgt aacactgaag ggcacgcatt aaggcgtcat cttaatgctt
       61 tcctgtagga cactgacgga gattaccagt ctcccgagcc ttacaggggc ctttcttttt
      121 tttgtatttt caattatcac aatttatcgt ccaaaagtgc agaacgaaaa tcaattcatc
      181 acaagcatat cagacaatta aatttaaaac aactaaaaat atacaaaaaa gtgtaattga
      241 atattagcag cactgcctga aaagaagtaa tatcaggctt ttcagcttgg ggaaataagt
      301 gaattacctc tcttcatgaa ttattataac tcaaaaaagc acatatgcaa acactagttc
      361 cctatttttt tgaatgaaaa ataactaaaa tatctaacga ttatgacttt aaaacctacg
      421 tttgtgattg ttttcataaa cttttaatct aaaaactccg gaataatagc tatttatttg
      481 taacatttgt aataaaatta aaatcataaa aaagttctaa tttaaaattg atcattttta
      541 tagtgatcgc tttttatcaa ctactctagc caattttccg tactaactgt tggtaattcg
      601 ttaaatgttt ctctttgttc gtttgcaagc tttgccgcaa tagctttttc gacaaaccaa
      661 ttttttacat aaacgaaaat tagattctgc aaattgttta ctttttcagt tttttgtttt
      721 tgataagctt tcagcaaagt catatataat cctttgtcag catcaattcc ataagattcc
      781 agttcttcat aaacaacaac tgtttgctct aattcttcag cttttttctt tgcattatga
      841 atagtttgga cggttttttg agcgtcttcg taagtactag aaaatgtttt tatcaagttt
      901 aatacatttt ctggtacaaa tgtatttata ctgtcctctt tcatgatgtc gacgaagtta
      961 tctagtaaaa cttgattttg taactgatca gtttcagtgt ctattatgtg tctattagtg
     1021 tctatagaat tagaatagaa tagattgtct gcgattttcg caattacggt tgagtccttg
     1081 atatgactgg attttgccgt atttgcgatt ttcgcaatta cggtggtatc attgatttct
     1141 cgcggttttg ccgtatttgc gattttcgca attacggtgg tatcagtatt gtcttcctct
     1201 tccatgattt taaagacgtc ttgattcgtt acttctggct tgcctaagta caataaatta
     1261 ggcatggatt caatcttacc gtcacgttta tttactcttc ctctcttctg tttcagaaga
     1321 cctgcttttt ctaattcctt tttgatttta gatactttac cttcgcggca ttgtaacaat
     1381 ttcattaatt cttcaactgt gaatatgaaa aatatattat catcagaatc tacccagtta
     1441 tttttgactg aataatcaaa tcgatcttta agtagcatat aagcaatttt tgcatcattt
     1501 gatagatcca tgtatttttc gttagtaaaa aataccttag gcatttgata atatttttca
     1561 cgataaattt cttttgattt gtaataatta aaatcattca tagccaatcc tctttctgta
     1621 ggatagcgtt ttgttcaaaa ctatgttaca atgaattaaa caaatatatc tatccactat
     1681 atatttttct actgctgata agtcgccaaa ctttgttaaa gcagtagtct ttttttatct
     1741 ttttttagtt taccttaaaa aataaattaa agcaaaccgc tctatttcaa ggtttaagct
     1801 catagtaact atatcacgat attacaataa tattatatca cgatatcgta atattacaat
     1861 atgaagataa gcgacttatc agctttgata ctactgattt ttataaaaaa aatatcacga
     1921 tattatgata tcgtgatatt gaatgtaaat taaattttat tttgtttctt tgctagttta
     1981 tatccttcaa tcaagtattc ttcaggtatg gactttaata gcgcatcttc tataacgtct
     2041 ggtttacttt tgtctgattc agcaatagtc gtccaatatt tgagtgctga cattagaatt
     2101 ggatttatac gaatgctatc tgctgttctt acactacttc cttgatcttt tatgacttta
     2161 cttatatttt tcttggttaa ttcgatttct tctacttctt ttgatttaaa attcttttta
     2221 tttttatttc ctagtaatct acttactgca gcttgactgc gattatcttc tgccatcaaa
     2281 atcaccaact tcttttaaat attcttctgt aaatgcttta tagtcatctt cagctgttga
     2341 gggtttatta aaattgatta gatctgatcc agcagcttgc gcttcgtcaa cggttattgt
     2401 cctacgaata taagttttga aaatttttgc accaatgact ctagaaattt cggttgctgc
     2461 agacgtcatt tctttagaaa tgttataacg cttattatac ttagtaaata gaactcctcg
     2521 tacttcaagc ttgtcgttcg tatattcttt taccgtttca atagtttcac ttaactttat
     2581 tagtcctttt aatgagaaat acgcagcttc aactggaatg ataatttcat cagaaacagt
     2641 aaatgcgttg actgtaagca ttcctaaact tggtggacaa tcaattataa tataatcata
     2701 gttgtccttg attggttgaa gtactctttt aagcctgtgt tcacttccta cttgagtaaa
     2761 ttccctctct gcagaagaaa gggctatgtc ggctggcaaa acatcaattc ctttatagtc
     2821 cagaatagca tctgtaatgt cagcctcccc ttttaatact tcataaattg taggttggtt
     2881 tgttccatct atatcgaaac ctacattatc tgtagcattt ccctgaggat caatgtccac
     2941 taaaagtaca tttttaccgt aaacaaattt caaacatgct gctaaattaa cgctagtcgt
     3001 agttttagaa actccacctt tttgattggc tactgacaat attcttgcca ttaaaatatc
     3061 ccccattcat cttatattat aatataatta tatcataata ttgtgatatt gcaatatcgt
     3121 atatgcatta tattgtaata ttgtgtgatt attttgtttt aaagatatat atcggttcgg
     3181 atataaagat tattcatatg ttattcgaaa ttaaaataat cactttttat tactttaaaa
     3241 ttttttatta atgataagaa atatgttttg cgagcagcaa ctagaataat ttaaacatta
     3301 ctaaactgtc tatattgtta ctaataattc ccttcttata gtgcattttc ttagaaaaaa
     3361 acaatattac gatatcatga tattaagata tcgtaatatt atacaattgt gattgatatt
     3421 atatatgttt ttttattttt ttatcatgtt taatcttgaa ggaatcatat tctttttcta
     3481 aagacaggag cttttcataa acatcagaca tgtttaaact agaggccagg cttaaatcat
     3541 aaacgaatga agcaggtaat gattttattc tacgttgtcg ggttatccag cttgcaaccg
     3601 ttccttgtgg gtaggcatat aactcacaaa attgttctac agtgattcct aaattcttga
     3661 taatgtaaac attgatcggg tgcgagtaaa caaatgtatt gatagacatg gtgcgtaagc
     3721 ctactttctt ttattattgc gtttgcaata atagtttaac acacgcatta ttctagtatc
     3781 tactcctatt tgtaaaaaca aaaaaggatt catagagata actctataga atccgtaaaa
     3841 taccttatat atataacggg aagatataaa acctaaaatt atgataacct gctgcagctt
     3901 ctacatagaa agagaagcgc tcaacaccaa cctcatttat caaacgttgg ccataacccc
     3961 aaatctcttc tgatagctga tcaaaggtta tatactttag ctcatattgc tggataatgt
     4021 tcattctaat cgactccatt tattatcctg gtaaaattcg atatgacgta tttcgtcgta
     4081 gtgaattttg tcttttccaa cgtagatccc cagctcatca ctacctaaga tcttgccaat
     4141 gatatcttct ggatagtatc cttcagcgtt tcgttcttct ttttgaatag atactgatct
     4201 attttttatg actgcagcgt tcaatacttc cgcaatctct tcagtcgtca tttgttcttt
     4261 tgctaaattt tgactggttc gttgttcatt gtcggcatca atttcttcag tatgatcaga
     4321 taaataaaac cctgcccact ttaaacgtcc acgatcattg taatcaatca tttttaattc
     4381 ccccatttcc gcccgcatga ccaccaacaa gtgtgcttct agtaatgctt ctagcgcctt
     4441 ctaacattga agaagcatgt acaatcgacg taaaaccata tttttgccga atcttgtcaa
     4501 taattttatc taaattttct tcgtcaattt gcttttgtgg atcactaaat aaatccagct
     4561 gaagcgaatc ggtgtacaca agcttgctat aggttattcc aacatgcctt acttcttgtc
     4621 cttcataata cttatcaaac aagaaaagac aataattctg caattccttt gtattatctg
     4681 tgatagggat cttcatctgg tgtgaaaacc ctggtctcgt ttctaagatc gacgtgccaa
     4741 tgtgtaaatg gacacaacct gttttacagt tatgctgcct aatgcgtatc gctacttgtt
     4801 ccgccatttc ttttaccacc agctcgattt catttcttct agtataatct cgtggtaaca
     4861 cttgtgaatt tccatatgat ttttcctttg tcggttctgg tgggattgct atatctgttc
     4921 gatcgatccc attagcatgg aagtacagct gtaatccaat cacacctaat ctattcttaa
     4981 tcgtataagg attccagtta gcaaggtctc taatgctcaa aattcccatt tggttgagcc
     5041 tttttttcat tcgcgaacca attccccaaa agtccgtcat ttcgggaata ttccatactt
     5101 tctcaggaac gttttcgtac gtccattccg caataaatcc ttcattatgc tttgcttcat
     5161 tgtctaaggc taatttagcc aaaaggggat tatcgccgac gcctaccgta gcaatcaaac
     5221 ctaactcttc tttaatacgt tcttggatca tttgagcgag cttcttcctt cgctgacttc
     5281 gtgtttcttc agtcgtaaaa agattcagtg attttgtcac ttttaaaatc gattcatcga
     5341 tcgagtaaat cagtagatct tcatcagcca catatcttct gaaaatatta tttacctgca
     5401 tatttcgctt gatatatagg ttcatacgtg gtggaacaac gtgtagtgtt ttaggaaatg
     5461 gttgtggtaa gtcacgtggt ctactcacat ttgtaatacc ataccgcttt tttgcttcag
     5521 gagaagaagc taatatcaat cctgaaccag tattatcaga tcgactcata acaacaagtt
     5581 ctgttgttaa tggatctaaa tttctttcta tacattcgac acttgcgtaa aagcttttca
     5641 tatcgattaa aaagtaatca tttactggct cttttgaata atccatcata aataacactc
     5701 cattcttcca cattatacaa acatatgttc gatgttgtaa agaagaaata gctaaatatt
     5761 tgagaataag ttatcagtag acacttacaa aaaattctca tactattgtc acttttctag
     5821 ataaatggca aaaattttca gcattaaatg acaaaaacta atgagaattt gtctttccat
     5881 ttttctcctc catttttgcc aaataacgat aaatggtggt tcttgagacg ttccaccgtt
     5941 ccgcaatagt cttaataggt gtaccgctat ccactaaagt cttcagtaat tccaaatctt
     6001 gttcagacaa tttttcagga cgaccaccaa accgtcctct tgcacgagca gctgctcgtc
     6061 ctgctgcgga tcgttccagg atcaaattac gctcaaattc tgcaaatgcc gcaaacaaat
     6121 gaaacatgag ctgtcctgta gaacttgatt tgtccatcgt aatattttct tgaatactat
     6181 gaaaactcac accacgctca ttcagtcgat tgacgattga aatcaaatct tccatatttc
     6241 tacctaaacg atctaagcgc caaacgacaa gtgtatcgcc agagcgaaca aaatcaatgg
     6301 ccatttctaa tcctggtcga ttactttttg ccccactcat atgatcagta aaaatttttt
     6361 cacaaccaaa tttatttagg ctgtcttctt gtaaatccaa attttgtaaa ccagtagata
     6421 cccgggcgta tcctattttc aaaaaaatca ctccttcatt aattttattg taacataact
     6481 ttatccatat agtttaactg aacatagata ttgttatggg tttatgaaca tgaaatgaat
     6541 tgtttttttg aaaaataaag caaaaaaaga aagtgtccag aaatgggtga ttttatgaac
     6601 actttcaatt agaaaaaaag aatgtcgact agacactctt tttttaaaat cattattttt
     6661 ctttttgata tgttttttgg tctctttttt ttcttttttc ttcagaatct tctagattag
     6721 aaattgattt ttgaattttt tgtgtctcct gtaaagttcg ctgaacttgt aaagctgatt
     6781 cttctttcgg taaattaatt ttacttagaa tatcgctatc ttgataaaaa tttggtgtgt
     6841 tcacaaattc tggcataaaa aatccctact ttctagttaa ggttcctgaa taagtcgcaa
     6901 tccaattgtt tccagctgat ttataacttt gtaaatacaa ttttccatag taccaataac
     6961 catttctttt ttctttccaa ttccgtgatt gaggaggtct agaaggccaa ccaactttat
     7021 caaaaatcat cgttcctgtc actcgtatcg ttttagaagc tgctcgagca agtaatggag
     7081 aaactattaa ataattttca gtaacagtta agtcgttagt tgggttacca atggctattc
     7141 cgttcctatc taaaggagtt aattcttggt tattatctac tacagtagtt ggttcatttg
     7201 tactatcagc aaatgtagga attgtagttc cagttacact aattccaata gttaaaatac
     7261 ctaaagataa aataaactta tttttcattg tctatcacct cgaaatcaaa aataagaaaa
     7321 cgttttctta ataaatctta acagataaat caagttatat actagaaaat tcataaaata
     7381 tatttttaat gtcataatcg tttaaatttt cttgattgac atttatttac aaaaaatatt
     7441 gccatttaaa aagaaaagtg acacatacta tttcctccat cattagtttt tgtctatata
     7501 aggtttaccc taaatagaca ctggtataac attgaaaaat atggcttcct cgtgtatgat
     7561 tagggtgtat tttaaatagt tgcagaaagt aggtaaaagt tttgagagtt gcatacatac
     7621 gtgtctcatc gatcgatcaa aatgaacaac gccagattga agaaatgaaa aaattcggtg
     7681 cagagagaat tttcatcgag aaacaatctg gcgcaacgat tactcatcga cctgttttcc
     7741 aagaagcatt agattacgtc cgagatcaag atatttttat tgtggaagct attgatcgac
     7801 ttggaagaaa ttatgacgag atcatcactt cagtcaatta cttgaagaag aaaaatgtga
     7861 agctgatcat tactagttta ccgatcatgg ctgaagcaat tggcaatcct ctcctggata
     7921 aattcattaa ggatctgatc atccaaattt tggccatgat cgctgaacaa gaacggactg
     7981 aatcgaaacg tcgccaggca caaggaatta agatcgcaaa agcaaacggc gtctacaaag
     8041 ggcggcccaa attatacagt gcagacgcaa aagatcccca acgtcgcctt gtttacaaaa
     8101 gcatcgttga agatcttaaa aatggtgttg cgattgctaa gattgctaaa gactacaatg
     8161 ttacgagaca aaccgtgtat agaataaaaa aagacagcat ggtcaatgac aaatagttga
     8221 tcatgctgct tttattat
//
LOCUS       DAFEEZ010000095         8199 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000095
VERSION     DAFEEZ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.099"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..572
                     /locus_tag="LP245_002644"
     CDS             <1..572
                     /locus_tag="LP245_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL1520505.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="LP245_002645"
     CDS             576..1217
                     /locus_tag="LP245_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1520506.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="LP245_002646"
     CDS             1214..2131
                     /locus_tag="LP245_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1520507.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="LP245_002647"
     CDS             2128..2799
                     /locus_tag="LP245_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1520508.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="LP245_002648"
     CDS             complement(3340..3828)
                     /locus_tag="LP245_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBL1520509.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="LP245_002649"
     CDS             complement(4029..4295)
                     /locus_tag="LP245_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBL1520510.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="LP245_002650"
     CDS             complement(4295..4558)
                     /locus_tag="LP245_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL1520511.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5034..5219
                     /locus_tag="LP245_002651"
     CDS             5034..5219
                     /locus_tag="LP245_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL1520512.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5361..7184)
                     /locus_tag="LP245_002652"
     CDS             complement(5361..7184)
                     /locus_tag="LP245_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBL1520513.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7782..>8199)
                     /locus_tag="LP245_002653"
     CDS             complement(7782..>8199)
                     /locus_tag="LP245_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HBL1520514.1"
                     /translation="FLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALFDNVGKGIAI
                     IILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWPNATKAIWIM
                     IGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
BASE COUNT         2464 a         1727 c         1561 g         2447 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgatttgatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag ttctatcctt
     7441 tttgatatct taacttttgg aagagagatg taaggctgct ttctacccat cattcttact
     7501 actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa agcttgcatc
     7561 tgcggtaata agctcaacca aattaaaaac ataagaagct gtttttattt ggtcgttctt
     7621 attacttgat gcagagcagc ttttttacaa cctcttggta cacggtgttc aatcagctga
     7681 ccctcggtat tagctcaaaa aaacggcaaa atatgaggaa ctatttttcc atttttttct
     7741 ctaatactca ggtcaaaaca ctgatttcac aacctctttt tttaatgaaa aatatggctc
     7801 tcatgcgccg cttctttgaa tttcgtcatt ttttcttcga tgaacggata gattgccgtt
     7861 cctacgattc caaagacaac aaacaaaccg atcatgatcc agattgcttt cgtagcattt
     7921 ggccaataaa ttcctcctgc agattcccgt aacaagttta ccgcatgagt aaatggcaag
     7981 aacggattga tcatttggaa gaatttccct gagacttgga tcggatagtt cccgcctccg
     8041 ccagagatcg acagtactaa gatgataata gcgatccctt taccgacatt atcgaataat
     8101 gcagccaaga catagacgat catcatgaac gctaaggcga tcaagacagc aaatgacacg
     8161 ctgtagaccg gattttggac atctactcct agtaagaaa
//
LOCUS       DAFEEZ010000096         8148 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000096
VERSION     DAFEEZ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.100"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..882
                     /locus_tag="LP245_002654"
     CDS             <1..882
                     /locus_tag="LP245_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBL1520515.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            930..3059
                     /locus_tag="LP245_002655"
     CDS             930..3059
                     /locus_tag="LP245_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBL1520516.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3034..3723
                     /locus_tag="LP245_002656"
     CDS             3034..3723
                     /locus_tag="LP245_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520517.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(4131..4817)
                     /locus_tag="LP245_002657"
     CDS             complement(4131..4817)
                     /locus_tag="LP245_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1520518.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(4953..5147)
                     /locus_tag="LP245_002658"
     CDS             complement(4953..5147)
                     /locus_tag="LP245_002658"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520519.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5197..5637)
                     /locus_tag="LP245_002659"
     CDS             complement(5197..5637)
                     /locus_tag="LP245_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBL1520520.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(5641..6486)
                     /locus_tag="LP245_002660"
     CDS             complement(5641..6486)
                     /locus_tag="LP245_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBL1520521.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6635..8053
                     /gene="pepV"
                     /locus_tag="LP245_002661"
     CDS             6635..8053
                     /gene="pepV"
                     /locus_tag="LP245_002661"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBL1520522.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
BASE COUNT         2505 a         1530 c         1730 g         2383 t
ORIGIN      
        1 atttcagtac cggttgcact gttctcattt atgggctcga ttatggctgg aatctttgct
       61 aatatcgtca atttcaaaca atatcaaacg atttatgctg gtttcaatcc agcggctgaa
      121 agctatactt ataatgacta tttccaaatt ggtatgattg ggatgattgt aagcttagtt
      181 gtggtactaa cggtcgctaa tatatcaatg aacaaaaaga aacgctatgc aatggcagca
      241 aacgtaccag ctgaaggtgg cgacgcacca atgatctcat ggttagccgt attattacca
      301 gttttagggg tcgttctttt agatcttcaa atcatcttag gttttattct agcaggtatc
      361 tgggcattgc tgtttactgg aaaattgcgc ggaggttata aagaaatctg tcgtcagttt
      421 gcgaaattat ttacagatgg cgcagtcgat gttgcaccaa tggttggttt cttgatgacc
      481 ttagcgatgt tcaataattc agctgcgtat gcttctcctt atttttcagc tatttttgga
      541 gattggatac cgcaatcacc attagtcttg gcaatcgtat ttgctatatt gacaccacta
      601 ggatttttcc gcggtccaat gaatctagtc ggttcaggct cagctatttt agctgtcgtg
      661 ttagctgtta atccaacgat gtcgccagcc tttttgttcc cgttatttgc aattacaacg
      721 attgctcctc agcatttaga tattacacaa tcttgggttg cttggggatt aggttataca
      781 aaagtaactt ctcgagaata tatgaagaaa tccatcccaa ctggttggat catcggtgcg
      841 atcttatgcc tgatcacgtt cttattgtac gggaacgcct agtaaacaaa acgtcgataa
      901 aaacgattag ataaatggag gaaaagaaaa tgaaacgttt tgtgcgaatg ggaattgatg
      961 ttggcggtac acatacgaaa gcagtcgcaa tcgataatgc gacgcacgaa atcatcggaa
     1021 aatcttcagt gaaaacaacc cacgatgatg tccgtggagt agctgcaggt gtcgttcagt
     1081 cttttcaaaa ttgtttgcgg gaaaataata tcagtccaga agatgttgtg tttgttgcac
     1141 attctaccac acaagcgact aatgcactga ttgaaggaga cgtagcaaaa gtcggcgtaa
     1201 tcgggatggc aaaaggtgga ttagaaggtt ttttagcaaa acgacaaact agattgaacg
     1261 atatcgattt agggaataag aaaaaaatag agattgtcaa tgcattctta cctgtcaaaa
     1321 acttaaatgt agaccgtgtt tcagaaacga tttcttcttt agaaagagaa agagcggagg
     1381 tcttggtttc ttctatggca tttggagtag ataatgggga accagaacga gttgtttatg
     1441 aagcagcatc tgtgaaagcg atccctacaa cgatggcttc tgacatcaca aaattatatg
     1501 gattgacaag aagaactcgg acagcagcaa tcaacgcatc tattttacca aaaatgctag
     1561 atacggcaac ctcgacagaa gactccgtac gagaagcagg ggtcaatgtt tctttgatga
     1621 ttatgcgcgg agacggcgga gtaatggaaa tcaatgaaat gaaaaaacga cctgttttaa
     1681 ccatgctttc cggtcctgct gcatcagtca tgggctcttt gatgtacttg agagcgtcta
     1741 atggtgttta ttttgaagta ggcggaacaa caaccaatat cggggtcatt aaaaatggac
     1801 gtccagcaat cgattattca attgtaggtg gccacccaac atatatctct tcattagatg
     1861 ttcgggttct aggtgtggca ggcggttcga tggtacgggc taatcagtca ggaatcatcg
     1921 atgtcggtcc acgttctgca catattgccg gtctagatta tgcagtattt acggagacag
     1981 aaaaaatcaa aggtcctaag gttgaatttt tctctcctaa agaaggagac cctgctgatt
     2041 acgtcaaggt agtgatggaa gacggagaag aagtgactat tacaaataca tgtgcagcca
     2101 atgttcttgg attagtgcaa gaagaacatt tttcttatgg aaatgtccca tctgcacgaa
     2161 aagccataca ggcattagca gactattgtc atacgacggt tgaagacatc gcagagcaga
     2221 tcatggaaaa atcctatgct aagattgaac cggtgatttt agaattggca gacaagtatc
     2281 acttggagaa agatcagatt tctcttgtag gtgtaggggg cggcgctgcc tcattgatta
     2341 cttactttag taataaaatg ggtgtgaaat attcgattcc tgaaaacgcc gaagtgattt
     2401 cttctattgg tgtagcactt gcaatggtcc gagatgttgt agaacgtatc atcccttcgc
     2461 caagtaaaga agatatacga tcgttgaaaa atgaagcgat gaataaagcg attgaatcag
     2521 gcgctacacc agaatcgatc gaagtccacg tagaaatcga tccacatact tcaaaagtaa
     2581 cggctatcgc tactggttct acggaagtga aagcaaccga tctaaccaag gagatcacaa
     2641 cagaagaagc actagagctt gctgcagagg atatgcgatt aaataaaaat gaagtttgct
     2701 tattggaaaa tacacctttc ttttatgtat gcggcgaaca gaatcgttca aaaaatgctg
     2761 gaagtcttcg gatcatcgat caaaaaggat ttatcaaggt ccaacgtgga catgcttcat
     2821 gtatgaaaac aactgcagcc aattatatga cagctgtcga acaactttgg gaagatatgg
     2881 cagtttatca aactgaattg attgcccgac cagaatttta tctctgctta ggagcaagag
     2941 tctctgattt tacagcgacg gatctggaac aactacagct tttgatggat ctggaagtat
     3001 ctactatgga accggaggaa gaagtgatcg tcgttgccgg aaatatcaaa caaacataag
     3061 ttagaagagt tactaaacga attacaacag atccccgaag aaatttgggg attctaccag
     3121 tttcggcgag atttattttg gaaaaagatt cctttgtcca agcagaaaat tcttatacaa
     3181 caatcaatcg attgtggtat cgaaacggca tgtagcatca aaaaaaagta cccttttgcc
     3241 gatgtaggag aaatctgtga acaaatggct gttccaatcg tttcctgtga atcagagcaa
     3301 ataaacgaac gaatcacttt tgcaacttat gcagaagatg aagggatccg attgatgacg
     3361 gagccgttag aaaaattaaa atgttcagga ctagcttcga tctctaaaga aacagcgcaa
     3421 gctttgatta ttggacatga actatttcac cacatcgaag cttctgttaa gggaatttat
     3481 acgcaaagcg aaaaaattgt gctgtggcgg ttgccttttt atacacatca atcaaacatt
     3541 cgtgcattga gcgagatagc agcgatgagt ttttcaaaag agatgaatca aagcgatttt
     3601 tcgccttatg tattagaggc agtcttactt tggccatata atgaaattcg tagccaaggg
     3661 atcttagaag aaataaaaga aatagaaaaa agatgtacgg agtatgattt agattacaaa
     3721 taaagagact gtgacaaaag tcgtgtcaca gtcctttttt tccgaataaa cggtgttctc
     3781 ctgtcaactc ctcggtcaca agtcaaaata ttcaacaaac atgagaagct gttttttgaa
     3841 attgttcctt gtgactcgga gatgaacggc aggctcacga cctcttggaa aaaggtgttc
     3901 aaaagcttgc atctgcggta ataagaacag ccaagttaaa aacataagaa gctattttta
     3961 cttggctgtt cttattactt gatgcagggc agctttttca caacctctca ataaacggtg
     4021 tgcaatcagc tgaccctcgg tattagctca aaaaaaacgg caaaatatga ggaactattt
     4081 tgccgtttat ttctctaata ctcaggtcaa aacgctgatt ccaaaacctc ttatttgatg
     4141 ggtctgtcct gaatatcttc aaaataatcg gggtaattat gaatcacgta ttcttgctcc
     4201 tcgataatca tatgtaaatg catcgtgcaa agaaatccga cttcatcaaa gttatgatca
     4261 atcattgatt gaagcattgt ctgatgttca tctaatactc gaccccagtc taattctgaa
     4321 atcgtcaaac gtaaccatct gaaacggttc aagtgcgtac tataactttc tagccaatcc
     4381 caaatttctc gttttccagc aatttcataa caagttcggt gaaaatcagt atccaaatca
     4441 aaaaaagctt ttttattttg agcgatcact gcctgatcgg tttgttctag tattttttct
     4501 agtttagctt gatcttgctt ggtcattttc gcactgcatt cttgcaggat cggtttttcc
     4561 aacttttccc gcgtataacg ggctaatgaa gcagatcgga tatcgatttt tgaaacataa
     4621 gtgccggact gtggaatggt ttttacaagc tcttgattgc gcagttggat cagtgcttct
     4681 cgaatcggtg tacgcccgat agctagttgt tcttctaaca ctttatcgga gattttactt
     4741 ccgggtgcta actcggaata aatgatttgt ttacgtatag attcataagc ttgctgttgc
     4801 aaattattga taaccattta accttccttt ctatgcagat ataatctatt ataacataaa
     4861 tcgcttacaa atcgtgtggg cataaaaaca cagtctgcaa aaaaagccct gataggcatg
     4921 cctattagag cctcgaaaag aaaaatattg aatcaatctg gtcgtacctc ttggatcggt
     4981 ttgacacgac cgccgattct tttagcaaaa gcttcggatt cttttttgtc tttgaaaatg
     5041 agcagattgt ctaagttttt ttcccgagtg cgacagccag ttttatcgat gtaaccgtgc
     5101 attactttaa cgacatacat ggggatcacc tgcttttttc ttttcattat acgaactact
     5161 cgacacaata caagaaaaat gcttagacgg tctttattaa gaatttacat catccaaaga
     5221 agcgtacgct tggaataact gttctaactc cggattgact ttgctcagct tcactaatcg
     5281 ttgcgaatca gaaagtaaaa aacagtgttt actactgcca gtagttttta attttttgtc
     5341 ttcagttccc acaatttcgt agctaaaatc caaccgtgtt cccgtatact tttggatagt
     5401 tgggtggatg ctcacttttt ctccgtaatg gatcatttct ttatagctgc aatttacttc
     5461 cagaacgggg atgatgatcc cagattcttc gattttttta tagggaaacc ctagatgtac
     5521 caataaggct acccgagcct cttcaaacca gcggatataa ttgctgtgat gaataatccc
     5581 catttgatct gtttcataat aaaaaggttc tcgcacataa cctgtaaatt tctccatgac
     5641 tcatgcctcg ttttccattg attttttaca aaaataattc atccacttcg gaagtgcttc
     5701 gctgatttgt gtcggcaaaa caatatattg ttcttttgcc agctggtctc caatgaaact
     5761 atgaagataa acagctgctg caatcgtttg gtcattttga ggaaactggg ctaaaaatcc
     5821 tgtgatcatc ccagctaaag tgtcacccat gccgcctgtt gccatagcag cagaacctaa
     5881 aggattggtg tagaagtgct ggtgaccata aatttttgtc tcatgacttt tcaaaacgag
     5941 cacagcaccg atttcctgtt gcttcttttt gttttcttta tcccgttgtt cttgtatcgg
     6001 tagagaactc aaccgttgcc actccatttg atgaggtgta agtacagttt gttcgggata
     6061 gggtagcaaa agatgattag caacaagtaa acttaaagca gagccatcaa tcaccagcca
     6121 ttgttctttt gattggtttt ctagtacttg tttgaaacgt tccaaactct tagaagaagt
     6181 acccaatccg ggaccaatca agagtacatc tgcttgcttt attacggaaa gaaactggtc
     6241 agtatccgtc caatctacaa tcattgcttc tggcagatga ctgtgaagag cactccgatt
     6301 tttttcatca gttactacag tcgtgagacc cgctccactg tgtacggcag ctaaagcact
     6361 cataatgatt gctccgccat attgttcatt gccgccaatc aaaacgatac gtccaaatgt
     6421 tcctttatgt gaaatctttg gacgaggtgt gatgactctt ttcactagtt gttcgtttat
     6481 cagcatcgaa aaacctcctt ttactcatta tagcgtatat tttttttaga gaaaaacaga
     6541 taagaaaagg aattgtcaga ttttttgaac tatttttttc tgtaatttgt ggtatcatga
     6601 acacgaagac ttaaataagt ggaggattaa ctttatgaca attgattggc aaaaagaagt
     6661 agaagcacgt aaagaagact tgcttgaaga cttgaaaaat cttttacgtg tcaacagcga
     6721 gcgcgatgat tcaaaagtaa caccagatgc accatttgga cctggacctc gcgacgcatt
     6781 gaaacatatg ttagcttatg gcgaacgtga tggatttaaa gtaaaaaatg tcgataacta
     6841 tgcagggcat attgatcttg gcgaaggaga cgaaacgcta gggatatttg gacacatgga
     6901 tgtcgttcct gcaggagatg gctgggacac agatccttat gaaccagtaa tcaaggatgg
     6961 aaagatcttt gcacgcggat caagcgatga caaaggtcca agtatggcag cttactatgc
     7021 gatgaagatc attaaagaac ttgacttgaa actatcaaaa aaagttcgct tcgtagtcgg
     7081 cagcgatgaa gaaagcggct ggggcgatat ggcttattat ttcgaacatg aagaagaacc
     7141 agattttggt ttctcaccag atgctgaatt cccaatcatc aatggtgaaa aaggaaatgt
     7201 ttctttagct ttacgcttca aaggcgacaa tgcaggagat tatgtcttga aatcttttgt
     7261 ttccggactt cgcgaaaata tggtgccagg aacagcaact gcagcacttc aagtaccaag
     7321 tgcagatgca gctatcgcga tggaagaagc attttaccaa ttcatcgaag caaatccagt
     7381 aagcggaacg attgaagcgg acaatacgta tgtaaaaatc gaattagttg gtaaaggcgc
     7441 acatggtgca agcccacaat ctggtatcaa tgcaggttct ttcttggcat tgttcttaga
     7501 taactatgaa ttcctaggat ctgctaaaca atttatccat gtagcagctg cttatgtcca
     7561 tgaagatttt tatggagaaa aactaggagt cgcttatgaa gatgaaaaaa tgggcaaatt
     7621 gacaatgaat gctggactat ttgcttttga agaaaatggt acagaggaag cgaacttcat
     7681 caatatgaat ttccgttttc caaaaggtgt aacagtagac ggattgcaaa gtgacatcga
     7741 acaaacagtg gggcaagaag gcgcaacagt tactcgaggt gctcgcgtaa tggaaccaca
     7801 ttacgtacca atggatgatc cattggtggc tacattattg caagtctatg aagaccacac
     7861 tggagaaaaa ggctacgaac aaatcatcgg tggcggaact tacggacgtt tgttgaaacg
     7921 tggcgttgct tatggagcga tgttcccagg atatactgat acaatgcatc aagcaaacga
     7981 atttatgagt cttgatgact tgttcagagc aacagcaatc tatgcagatg ccatctatcg
     8041 tttggcgaaa taaaaatact aaaaaactgg ctctttgtca ataaggactg atgagttgtg
     8101 caaaatcaaa tctgagtcag aatgaaccac attctggctc agattttt
//
LOCUS       DAFEEZ010000097         7651 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000097
VERSION     DAFEEZ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7651
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.102"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(995..1408)
                     /locus_tag="LP245_002662"
     CDS             complement(995..1408)
                     /locus_tag="LP245_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBL1520523.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1864..2349)
                     /locus_tag="LP245_002663"
     CDS             complement(1864..2349)
                     /locus_tag="LP245_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520524.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2488..2733)
                     /locus_tag="LP245_002664"
     CDS             complement(2488..2733)
                     /locus_tag="LP245_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBL1520525.1"
                     /translation="MFYHLRKENSNENLDAIALTLLIVGGLNWLLVGLFELDLVAMIA
                     GGSTTIFAKIIYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2926..3726
                     /locus_tag="LP245_002665"
     CDS             2926..3726
                     /locus_tag="LP245_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1520526.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3745..5613
                     /locus_tag="LP245_002666"
     CDS             3745..5613
                     /locus_tag="LP245_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL1520527.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRSYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELCDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5606..6097
                     /locus_tag="LP245_002667"
     CDS             5606..6097
                     /locus_tag="LP245_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBL1520528.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6085..6639
                     /gene="srlA"
                     /locus_tag="LP245_002668"
     CDS             6085..6639
                     /gene="srlA"
                     /locus_tag="LP245_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBL1520529.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6657..>7651
                     /locus_tag="LP245_002669"
     CDS             6657..>7651
                     /locus_tag="LP245_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBL1520530.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2718 a         1223 c         1446 g         2264 t
ORIGIN      
        1 cttccttttt tgtatggatt ttttcattta cacaaaatat tttatactct cttttgttac
       61 tatgaataac ataataagaa agtaaagtgg attgatttga gatcttttta tacttcaaaa
      121 aagataacac ccaactttca aaaatatgtt ttggaagttg ggacaaacga gttaatacat
      181 tttaatacat tattttttat tcaaaaaaaa tagcacaatg gcaaagatcg taagagagat
      241 cataagcccc aatgaatgac taaaaagaaa agcagaatca catgccatat catcccatat
      301 ttcttcaaga aaataaataa gcgggaaaaa gggaaggaat agtagaacat cgatccagca
      361 ccattttttt cttcttttga aataacataa aacaataaac atgaacgtgc agggaagtaa
      421 aaacaaagct ttactcataa ctaacaaaat accagctcct tttatttttt tctcccccac
      481 attcaaagag taacaatggt atgtacttaa taatagaaaa atggatcaac ttgtatgaat
      541 aacagctgaa aagatctgca ccaaataaaa aacttccagc caaaactgac tggaagttta
      601 tttttttctg aaatattcta acacaaatat gaaaaagatg gccgaagcta ataagccgat
      661 ttcgtagcaa aacaatgaga taccagagtc gtaataataa aatcctctaa tcttatggat
      721 aaaatagatc atcggacaag cagataagag taagtatttg ttaggccttt tgaataagta
      781 aaagaaagca ctggtcatta tgataaatgg tatccaaaac aaaagtttac ttaagacaat
      841 caaatgatca actcccatat tttttaccaa gagagatcat aacatcttta tcgtaaaaac
      901 aaaatatttt tttgctcatt ttgaaaattt aaacatactc gttcttatcc aaatatataa
      961 aaatcgcccc tcattcatcg agaggcgata agttctaatt taactcaatt ttttttgttt
     1021 cttttggctg ataagctgtt ttaggtaata ccaatttcag cacaccgttt ttaaaggttc
     1081 cagtgatttt ttcttcatca acattaggaa gatagaatga acgtttgtaa gagaccgaat
     1141 gtctttcttt ccgtacatag ttgccatctt ctttatcttc tgtatgggac tcatgattgg
     1201 cggagatcgt caaagtatta tctgaatatt caactgtcgt gtcttctttg tcacagccag
     1261 gcatatcagc agttagtttg tattcttttt cattttcgac taaatctact tttggataac
     1321 ttgaaacacc taaaaaatca ttgaatgctg gactaaacac gtcattgaaa tcagggaaca
     1381 tgtcgcgaat gctaggtaca tttgccattt ttgatcatcc tttcaataag tattttttat
     1441 ttatccctat ttacgtaata actctatttt gaaaaaaatg caagtataat ggttagcttt
     1501 gtgaatattt catctaatac gatacaaagg ctatctttct aatttgaaaa agggatcatt
     1561 aaaataataa gaagaaaata tgtcaaaagg taaaaaagta aattcttcta tccaaatata
     1621 gaaaaattga atctagaaaa ccgcccgaca ataaatttca ttaactcagt tgaccgaaaa
     1681 tgaagtagat accaaaaatt tatcaagaga gcaagtagag aagtgagtat attcataaga
     1741 gaaatagctg taacgaatta ttaggttaat gcaaatgctt atttatactc cgtataactt
     1801 tctcagaaaa aatgatacca ataatgactt gctagtactg taaatccgta taatatcatc
     1861 taatcaaaat ggtgttccat ttgcatctgt catcgtaatc gatccttcgg gtgacactcg
     1921 ataaaaacca acgcttccag atcctccttg ggaacggatt tgtttgctgg aagctgtgaa
     1981 caaataatct cgatcaattt tttgataaaa gctaataaca atatcgtcac tttgtaattc
     2041 ggaacggtgg gcaataagaa atagaagtgc tttgtcagag ttttctaatg gaagagaagg
     2101 tacagtgctt tcttgcattt cagatgttga agaaatgcta aacgactgaa tacttgattg
     2161 gctatgttgc gaatctacat taccagtaga agtattagta atggaagtag tagaagtact
     2221 tttagttgaa ccaacctcag ttgttgaaat ggctgctgaa gattctttaa cagaattctt
     2281 tgttttatat ccacaggcag aaaaaagtat tacagttccc aacaagcctg cgtaaatccc
     2341 tttatgcatg atagctcctc ctaaaataga ttatctttat tcagtatatc acttaaacaa
     2401 agaaaagcag atggtttaaa atgaaaaaac cttcccaata aagggaaggt tcatgaagat
     2461 aataactttt ttaataatta tagctttcta atatctttca tcaacttttc tagtaatcat
     2521 tgggaaaaat ttcaagcagt agatcgcaca aatacctacg acgatataaa tgatcttcgc
     2581 aaaaatagtt gttgaaccac cagcaatcat agctactaaa tcaagttcga acaagcctac
     2641 caacagccag ttcaaccctc ccacaatcaa taaagttaat gcaatagcat ctaagttttc
     2701 attagaattc tcctttctta aatgataaaa caattatata tcaaaaagag aaacattgct
     2761 tatataacgc tcaggaattt tagcaatcta tgcaaaaaga tgaaaatttt ttttgctctt
     2821 ccattagtac acatttttta gctgaagctg taaatttcat gtcttaattt tttttagtga
     2881 gcttttatac tggatttgta agaaaaaaga aggagaggat cacatatgtc ggattggttg
     2941 gatattgcag gaaaagtagt aattgtaact ggaggttcct caggaattgg aagaagtatc
     3001 gtcgaaaatt tgttgaagca gaatgcacaa gtagcgaatt ttgatgtaac tgaatgccgt
     3061 atacagcatg aaaacctact atctttaaaa gtcgatgtgt cttctaaaac ggacatagaa
     3121 gaagggatat ataaagtaat gaaacatttc aagacgatcg atggtctagt caataatgca
     3181 ggaataaata ttccttctct tctaatagat agaaatcatc caaaaagcaa gtatgaatta
     3241 tcagaacaag tttttgataa gatgatcgct gtcaatcaaa aaagtgtata tttgatgagc
     3301 caagcagttg gaagaatctt ggtgcaaaag ggatcaggag tgatcgtgaa tctttcttct
     3361 gaatcaggat tggaaggatc agaaggacag agctgttatg ctgctacaaa agcagcgatg
     3421 aacagtttta ctcgttcttg ggcaaaagag ttaggaaaga ggaatgttcg tgtggtaggt
     3481 gttgcaccag ggatactgga agaaaccggt ttgagaacac aagaatatga agaagctctt
     3541 tcttatacga gaggtataag cgtcgaacag ctgagaaacg gttacagtcg aacaagtacg
     3601 atccctctag gaaggagtgg taagctgcaa gaagtggcgg atctagtctg ctattatctt
     3661 tcagaaagat caagttatat cactggagtc acgactaata tttcaggagg taaaacaaga
     3721 ggataaagga taggggggac gcacgtgacg ctagtaaaca gatggtacca attattgaaa
     3781 ttactagtca ctcacaagaa agtttcaatc caggaagtgc aaaaagaaat caaaaccagt
     3841 aatcaaacca taaaaaaaga tattggggag ttgaatgaag aaattgccgg tattgcaaaa
     3901 atcatccaaa aaaacaaaca ttttgaactt gaaatttatg attttgattt ttttgatgag
     3961 atcatgcaag gaaaattgaa aacagccagt gatttcaatt cggcatccaa aagaatcgct
     4021 tatttactaa ataggctgat cgaaacagag gatttcttac gtatggatga tttgtctgaa
     4081 gaagtcggtg tcagcagagg aacagtggtc aaggatctaa agacattaaa agagatgatc
     4141 aatgattttg atgtaaagat tacaggcaca ccaaataaag gactaagaat aataggagat
     4201 gagctagaat tacgactact tttattttat tttgtttctc cctacttttc agagacgaaa
     4261 acagaacagt ttctagaaga aaaacaagca atcaaacatt ttcagaagaa gacgaatgct
     4321 agtaaacaag aaatcaccct tttaacgaaa gttatcggta tttctttgaa tagaatctct
     4381 agtaactatc tgttgaagaa gcccatcaat cgttacagtg ggtgttttga atatatccaa
     4441 gaattcaatg aactgatcaa tcagttggaa gaaatctatg aactaacttt gagccaatat
     4501 gaaaaagatt ttatcagttt tcctttgaac atcatcaaca caagtataac gatgataagg
     4561 aaagctaact ctgatttgcg cttatatttc gaccccatga tgatgcgtat tcgacgatta
     4621 gatctcattg atctggatga gtccttctta tatcaagaga tgaaacagca cctctcttta
     4681 ttgataaatc gggtaatttt tcgttatcga ttgactgatt tattttatgg tgagatagaa
     4741 aaaaagtatc ctttttctta ccaaatcgct agcgaatgca tacaagcatt agaagctatc
     4801 ttgcaacata agatctctaa agtagagatc agctacctaa cgttgtattt ggagttagca
     4861 tttcgatatc aaaaagagca tttttcctct aaaaaagtag ccattgttca tacgacagga
     4921 aaaggaacag cattaatgat ccaaagacaa atcaaaagga tattggggag ggatatacaa
     4981 ataacacatg tttcagaaga acaatatgaa aaagtagatc taaacaaata tttcgctgtt
     5041 tttacaacga ttccgttaaa aaatgtaaat gaagagacac cggtgatcca tttgactaat
     5101 ctttttgatg actcttggtt aagggcacaa tggcaaaaag caaaaaaaaa gcgattagcc
     5161 gggtttcatt ctactgtttt tttctatcaa atatggaaag aaaaaaagac gtatcaagaa
     5221 tatttaaaca aattagtcgc tcctttgatc agaagctatt atgtggatga agaatttgaa
     5281 aaaaggatct tgaaaagaga atatcagcaa agcacatttg ttaacaaaga atttgctttt
     5341 cctcacacaa ccaaccagct atctcaacac attgttttat cagtagggct aataactgat
     5401 caaggtttag cagaaacagg aggaaatgga gttatttttt tatttgccat acctgaagaa
     5461 atgacggctg aagttgagaa tgaattattt gagctatgcg atatcctatt tgaactcata
     5521 aaaatgggaa tagatgagtt tattgaatta gcaccgacac aagaatcatt tttaaaacta
     5581 atcaaaagta aaggagagag acttcatgaa tgatatgtat ctattcatag ttttcgcagc
     5641 ttcagcttat gtgctgcaag cagttatcag ttggaagcaa ctaaagcatt tcaatcaaac
     5701 atatagcgaa ctgcgaagaa aaggaaaagt agcgattggt aaacgacctg ggaaaatccg
     5761 ttcaggcacg attgttatgc tagctataga cgatcatgat caagttttag aagtcagaaa
     5821 aatgcaaggg gttacatctt tggcaaaatt tcattcatta cctgtctatg cgggtgaaga
     5881 tatccattac atcgatcgtt accatccctc agttcgagcg gaagatcgtt tgacacaagc
     5941 agctttagaa aatgccagag aagtatactt acgaatagag gcaggaaatg aaaaaagtga
     6001 acaaccttca ttgcctttta ttgctatgct caataatttt cggatatgga aaagtacgat
     6061 caaagaaaaa aggagtgaca aacgatggat atcataacaa aatttgctga gggatttatg
     6121 aggctgttcc aaacaggtgc agaaacattc ataagctgga tgacaggaat cgtaccagtt
     6181 gtcttgatgc tgatggttgc aatgaatacg ctgattgctt ttttaggtga agaccgagta
     6241 acgaaagtag ccaaattatc agcgaaaaat ccgcttactc gttaccttgt gttaccgttc
     6301 ttatctgctt ttatgttggg aaatcctatg tcatttacaa tggctcgttt ccttccagaa
     6361 tactacaaac caagctatta tgctgctcaa gctcaatttt gtcatacgag caatggtgta
     6421 ttcccccata ttaatcctgg agaattgttt gtatggatgg ggattgctca agggatcgaa
     6481 accttagggc taaattcgat ggagctggct atccgatact tgcttgtggg actgctgatg
     6541 aactttattg gtggttggat aactgatttt actactggat ttgtatgcag acagcaagga
     6601 atcgttctta gcaaaaaagt agagctttca gttgattaga gaaaggagag ttttaaatgt
     6661 atggtgatat taagatcgta agaggaaacg gcgggtatgg aggtcctttg attattaggc
     6721 cgacaaaaga taaacacaag ttcatctatg tcacaggtgg aggtgagagg ccaatgatcg
     6781 tagataaaat agaagaactg acaggtatgg agtctatcaa tgggttcaaa acatcaatac
     6841 ctgatagtga aatcgcgctt gcaatcgttg actgtggagg gactcttaga tgtggaattt
     6901 atcctaaaaa agggatacca accatcaata tcgttcccac aggaaaaagt ggcccattag
     6961 cacaatatat cactgaagat atttatgttt cagcagtagg gttagaacaa atacagccac
     7021 taatggaaac tgatgataac aaagaaacag taaatactgc atctccagat aaaaagtaca
     7081 aatatgatac ttctaaaaag ataaccgagc aaaaagcaga gcagcaaaac tggatagcaa
     7141 aaattggaat gggcgcggga aaagtagttg ctacattcaa tcaatcagca agagaagcag
     7201 tagatacgat gatccggaca gtgatccctt ttatggcttt cgtttccctt ttgattggtg
     7261 tgatacaagg ttctgggatc ggtaatgtat ttgctaacat tatggcacct ttagcaggaa
     7321 atgcagttgg attaacaatc attggcttta tttgttcact gccattttta tctcctttgc
     7381 ttggtccagg ggcagttatt agccaagtga ttggaacatt gatcggtgta gagattggga
     7441 aaggaaatat tcctccccaa ttagcattac cggcactatt tgctatcaat actcaaaatg
     7501 catgtgattt tattccagtc ggtctaggtt tggaagaagc aaaagctgag acagtagaag
     7561 taggtgtacc atcagttctt tattcaagat ttcttaacgg catcccacga gttatcattg
     7621 cttgggtagc aagttttgga ttatatagct g
//
LOCUS       DAFEEZ010000098         7604 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000098
VERSION     DAFEEZ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.103"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(37..642)
                     /locus_tag="LP245_002670"
     CDS             complement(37..642)
                     /locus_tag="LP245_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBL1520531.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVASYGMICSARELHLPNAPEKKGILVLPEDAVVGEVFPK"
     gene            complement(838..1302)
                     /locus_tag="LP245_002671"
     CDS             complement(838..1302)
                     /locus_tag="LP245_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL1520532.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKALEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(1324..1644)
                     /locus_tag="LP245_002672"
     CDS             complement(1324..1644)
                     /locus_tag="LP245_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBL1520533.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VIKG"
     gene            complement(1787..2866)
                     /gene="pepA"
                     /locus_tag="LP245_002673"
     CDS             complement(1787..2866)
                     /gene="pepA"
                     /locus_tag="LP245_002673"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBL1520534.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            3066..3416
                     /locus_tag="LP245_002674"
     CDS             3066..3416
                     /locus_tag="LP245_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBL1520535.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKTSFLKEGAIEGAWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLDISRKKGAID"
     gene            3601..4554
                     /locus_tag="LP245_002675"
     CDS             3601..4554
                     /locus_tag="LP245_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL1520536.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            4567..6354
                     /locus_tag="LP245_002676"
     CDS             4567..6354
                     /locus_tag="LP245_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520537.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            6341..7543
                     /locus_tag="LP245_002677"
     CDS             6341..7543
                     /locus_tag="LP245_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520538.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
BASE COUNT         2168 a         1446 c         1365 g         2625 t
ORIGIN      
        1 aaaaagaggt tgtgacaaag acttgtcaca acctctttat tttggaaata cttctccgac
       61 tacggcatcc tcaggcaata ctaagattcc ttttttttct ggagcatttg gcaaatgcaa
      121 ttcacgagca gaacaaatca ttccatagct ggctacccct cgcaaagttc ctggccagat
      181 catcattcca tctggcatca tggctcctgg ttttgcaacg acaacttttt gtccagcttc
      241 gatatttggt gcaccgcaaa caatttgcaa tactgtccca ttgtccactt ctgtctcagt
      301 aatcgataaa tggtcagagt caggatgcgg gacgcatgtt tttacatacc cgacaacgat
      361 cttcggttca tgatcagctt caagctgttc ttcgaatcct gcttctttaa tcaatcgatt
      421 caatttcgct aattcttcat ctgttaagct tacttggccg ttcccttcaa ttgttagatg
      481 atcggagata tggaaaaagt tccaagcaac aacttgacct tgttcatctt tgatccgagc
      541 aacattccat ttacgttcga cagtgttttc tgttccttta tcgtcggcta tgataaccat
      601 caaagtgtct ccgacgtgtg ctttgttata agcaaaaatc atgttctttc ctccattatc
      661 ctttgctgag atttatctta acaaaaaatt gcattcactg catgagattt ttttcatgct
      721 ttatttccga agaagcttct tctggaacac catttattcg taacaaggga ctgtgacaag
      781 acttttgtca cagtcccttt actgtttgat taaaaaggtt atacaagttc cacttgctta
      841 attactcggc tgttcttctt cgtcagaaac gatcaagaca tcacaaggtg aatgacgtat
      901 gacgtagctg gctacacttc ctgtcataaa gcgttcgact gcatttagtc cagactgccc
      961 aaccatgatt agatcgattg catatttttt tggcaatttg actgccatgg attcacgaac
     1021 agagccgtat gcaataattc cttctatatt tgtgtaatca acagattttc catattcttt
     1081 acattcttcg atcatttgct tggctgtttc agtttgctga tcgactagat tttgatcaat
     1141 aggagcatag cccataaaat tataaaattg ctgatcgatt acgtttgcta catatacttt
     1201 cccattatta cggcgagcca cttctaacgc ttttttgaaa gcagcaagtg cttgttcact
     1261 accgtcaata cctactaaaa tgttcttata ttcttgattc atcttgaccc ctcctaacag
     1321 atgtcagcct tttattacac tttctaggaa cgattcgatt tcctgttttg ttttacgatc
     1381 tttattcact agacgaccta attcttttcc gtcttggatc acgacaaaac ttgggatacc
     1441 aaaaatgttc cattcagcgg ctacatctat gtacttgtca cggtctactt caataaattg
     1501 ccaatcagaa aagtcatttt cgatttcagg catttgcggt ttgataaaac ggcagtctcc
     1561 gcaccagccg gcagtaaaga aaaatacact ttttccagtt tctacgtagc ctgctaattc
     1621 ttctaaacta tttgggataa tcattctttt tcctctactt tctgtttatg tatttttcaa
     1681 ttaaattata cacctttctt tcgaactaac aaacattgat cctcttttta taaaaaaaat
     1741 ctgacaaaag gttgcttttg ccagatttta tagtttcact atcgcgttat ttcccgtata
     1801 cgatcgtgtt cactgttgat ttatctaaac ctttcaatgt ttgaatcaac atttctcgtg
     1861 cagcttcaaa atcgcgaata ctgaacatcg tttgatgcgt atggatataa cgtcccacta
     1921 cgccaatcac tgtacttggg attccttcat tttgtgtatg agcagcacct gcatctgtac
     1981 cgccttttga aacaaagtat tgataaggga tgttgtttgt ttcagcgata tctagcaagt
     2041 actcacgcaa acgaggaagc atgatcaaac ctggatcttg gatacgcatc aatgtacctt
     2101 ctcctaaatg tccgaatgtg ccatttttcg tcactgtgtc atctgctgca gagcagtcta
     2161 ctgcaaagaa cagatctggc ttgaatttat tgacagaagc tttagaacca cgcaagccta
     2221 cttcttcttg gacattcgcg cctgcaatca atgtatgacc taatgtttca ttttgtaacg
     2281 cttctaaagc ttctaatacc attgtacagc catagcggtt gtcccacgat ttgctgatga
     2341 tattcttccc gttggctgtt ttgatcgttt cagcgtaagg aacgattgtg tctcctggaa
     2401 gaacaccgta actcattgcc tcttctcttg attcaaaccc agcatcgaac aaaatatctg
     2461 ttacttctac tgatttttgt ccgcttgttc ctcgtaataa atgtggggga acggaagaag
     2521 aaatacatgg ataattctta ccagtagagg ttttaagtgt aaaacgttga gcagaaacaa
     2581 cgtaagggtt ccatccgcct agaggtacga ctttaaaaag cccgttttct tggatttgtg
     2641 tcagcatgaa tccgacttca tccatatgtg ctgcgaccat tacacgaggt gcatccgctt
     2701 cttcatggtg gcgcagccca aaaatgccgc ccaaaccatc taactgtaac tcatctacca
     2761 gcggttccat atgactttcc atataggcgc gaacgtcttg ttcaaaaccg cttgttcctt
     2821 gtaattctgt taactctttg attcgttgaa atgttttttc ttccatatgc tattcgtcta
     2881 aatttcagac taaactcctc tcagacttat attgatctgc ggataaaata tgattttttc
     2941 tgcagaccga tcgtatttat tatagcttat tttttctggt agcggttatt tatttcaaag
     3001 aaaatatgag agtgtggtaa aataaacaca aagagtagca agtgagaaga aggaggtata
     3061 tccacatgta tgaagaaagc gaattaagct attttaaagg cgggttagcc gttgggatcg
     3121 gtctaggatt attgagtggg gtagcttcaa cgatttggta tcatcgcaaa aaagtgttat
     3181 cagcagacca agtgcttgaa aatatcaaaa catctttttt aaaagaaggc gcaatcgaag
     3241 gtgcttggat ctcttttgaa aaagaaccta ttcggaaatt cgccgttcgg tcgagtgctt
     3301 atcggggtgg gctttcccgg atagaagatg gcgaaactgt ttattatgaa tttttagcag
     3361 atgctcatac aggaaccgta ttagacattt caagaaaaaa gggcgcaata gattaatacg
     3421 tcaaaaaaat gaaataacga atacgcaccc actatctaaa agagaggtat cctatccttc
     3481 ttttatagtg ggtgattttt ataaaaatag ggctatttcc tcttggaata gctagtattt
     3541 gtagttatta tacggtattc ttgaaataag attagtttta ttatataagg agagtgacaa
     3601 atggaatcac gtgaaaaaat tgccgtgctc attccttgtt ataacgaaga ggcgacaatt
     3661 tcaactgtta ttgaagattt taaaagggaa ttaccagaag cagatattta tgtctatgat
     3721 aataattcga ccgatcgaac atacgaattg gccgttcaag gcggagcaat cgtaaagaaa
     3781 gaaccacgtc aaggaaaagg gaatgtaatc cgtcaaatgt tttttgatat tgatgccgat
     3841 tattatttga tggtagatgg tgatgatact tatcctgcag aagctgcaca tggtttgctt
     3901 gagaaattac gttctggcga agcagatatg gtcattggcg atcgtctatc aaatggaacc
     3961 tattttgatg aaaataagcg tcctttccat gattttggga ataatctggt taaaaataca
     4021 attacttact tatataaaac aaaaattcgc gatgtcatga ccggctatcg aggattcaat
     4081 cgaatttttg tcaaaagctt ccctattatg agttctggtt ttcaaatcga aacagaattg
     4141 acgattcatg ctttagataa aaaattcaag ttcgttgaga ttccaatcga ttatcgcgat
     4201 cgtcctgaag gtagcgaatc aaaattgaat acattctctg acggattcaa agtgatcatg
     4261 atgatcatca aaatgtgcaa agattataaa cctttgcttt tctttgggat ctggaccatc
     4321 ttcttctttt tatttggatt ggtcatgggg attcctgtga ttcgtgaata tatgctgaca
     4381 agctttatta cacgcatccc ttctgcgatt ttaagtactg gattgatgac tttagccctt
     4441 ctttcattag taacagggtt gattttggat acggtcgtca caaatgccaa gaaagaatat
     4501 gaattgaatt tataccatgt ctaccacgaa tatcaaaata aagaaatgaa gtaggaggcc
     4561 ttttttatgc ataagaaaaa ggagaatcta tttcctactt tttttgcaac tttatttgcg
     4621 tcaggttttg ctttttttac ttcttatggt ctaggaactt tgaatccaac agtaatcatt
     4681 ggtttagcca tggttttgct acttgctttt aagcaatatg gaatagagtt gttttcaata
     4741 aaaaacaaag ttgcagctat tgcccgattg tttttttctg cagcttttgc tcttacactt
     4801 tctattggca gacagataca atttcagtat gtctcagcaa actatacaaa gacaacgatt
     4861 gctgatggaa gtatttttta ctttcttgtt tatttctcca tttttgtgta ttctttttta
     4921 tttttacaat cgatttattt atcaatgcca aaactggaaa cattttttac tgctcaaaac
     4981 acacaggctt tctcttcaag aaaatatttt ttattcttta ctgtcttttt agttctgtgt
     5041 tggcttcctt atctgttggc attgtatcct ggagtggttt tgcctgattc gttaagttcg
     5101 gtcgcccaat ctatgggtga tgttcctata agcaatcatc atccagtctt attcacctta
     5161 ctggtcaagc tatttgttca tgatttacca actgatacga tcaatcacgg tgtattttta
     5221 ttttcgattt ttcaaacatt gataacagct tcagcgataa gttattctct ttgctggctg
     5281 ttaaaaagaa acatccattt ttttccggta ctcattagtt tatgctattt tgcatttgca
     5341 ccggtttttc caatctacgc cttgaacatg caaaaagata ctttgttctc tatcgcttgc
     5401 tttttatttt ccttagcggt ttttgacttt atttttcaac gagaaaagcc aacgattctc
     5461 aatcagattt acgtaatcat ccttgcttta ctgaccacct atctaagaaa taatgggatt
     5521 tatgtagtaa ccggcacagg tttgatttgc ggcttgatta ttttgaaaca aaaaaggtat
     5581 caagcattct ttcaagtggt gctgggttat acagtgattg ctggactact catccacccg
     5641 ttgatggctc gttatgctat tcctacagaa actgctgaac aattaggtgt tcctttgcag
     5701 caaatttcta gaactattgt tatggatggt gacttgtcta agaaagataa agcattcatg
     5761 aatcagctac tcccgataaa agattatgaa gcgtattctc ctagtcttgc agactcaatc
     5821 aagtggcata aaaattttaa caatgagttt ttgaatacac ataaaaaaga atttctatca
     5881 ctatgggcaa gaaatttacc aagtaatata aaaatctata cagatgctta tattttagaa
     5941 acgttcgggt tctgggtacc tggtacaaaa aatagttacg gctttttaga tactcgtgta
     6001 aacacgaata attatggtat gaagcaagta gatttgattg aacatcttac tggattgtca
     6061 ggaatgaaaa aaatcatcga tgctcgtgat ttctttggtt ccggcacatt actgtggtta
     6121 gctatcggca gtgcactttt agcaatcttt aagaaaaaat atcggtattt actccttttt
     6181 cttcccggta tgcttgtttt tgctactatt atgattgcta ctcctgtggc ttttagttta
     6241 cggtatgtgt ttgttttagc attaggtcta cctgtttata tcctctctcc ttttttacta
     6301 gataaaagag aaaaaatgaa aacagatata ggagatactc atgaaactat ttaaaaagat
     6361 attttttgct tttgttctct tgatcgctag ctattgcgta ctactgacaa ttactttttt
     6421 cattccgcag cactctattg aatcgaatgc agaaaaatct ctacagatgg ttgaaaaaga
     6481 aggaatgtat ccttctatca atcaaggaaa tatgctaggc actcggttag ataattttac
     6541 tgatcatttg atgatacgaa aaacaaaagc agatcctgaa ttgaactcct tggagaacgc
     6601 gatgtctatg gcggattatc cccgttattg gcatggttat cagctttttt tacgaccttt
     6661 actgctaggg atgagtttgg ggagtattcg aatgatttac gcagccattc tttttctgct
     6721 gattggattg acgagctact ttttaaccaa gtgtagcgac atctatttaa cgacagcctt
     6781 gttgatttcg cttgctatag gaaatgctgc aacctttttc ttcagtatgc aattttcaaa
     6841 tatttggatt ttgactttat tgtctgtatt actattttta acaaaaccac aactctccaa
     6901 caccaaccaa caattattct tgtatttctt tgtcattggt tctttagcta acttttttga
     6961 cttgttgaca acaccggtca tctcttgggg gatacctgtg atcattattt attatgtaac
     7021 aaataagtat ttaatggata aacgcagttc attgagcaaa caagtaggca gttttgtttt
     7081 taccggtatc ttttggggat taggctatgg tttgacatgg gtggctaaat ggatcctatc
     7141 atcgatcata ttgaacaaaa acattgtaaa agatgcaatc aaccaaatcc tctttcgaac
     7201 ggaaggaaac gacaaatacc cgttgcatcg attagagatg ctgaaaagca atattagatt
     7261 gatgtatcca aaagtagcaa tattattgct attgattact tgtcttgttt ttctctattt
     7321 tgcttatcgt aaacgaaata gctggcgtcc gttccaactt ctagttttgt ttgttttagc
     7381 tgctgtaacg ccgtatattt ggtacaatat tttagctaat cactcacaga ttcattattg
     7441 gtttacgtat cgtacgcaaa tcatcacaag ttttgctata cttagtgctt tcgccttttt
     7501 gatccctcct gagaaatcaa aagacgaact aaattacttt taagaatacc gatgtactaa
     7561 ttcattttta aacataaaaa ctccagctgt cagagatagc cgga
//
LOCUS       DAFEEZ010000099         7165 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000099
VERSION     DAFEEZ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7165
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.104"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..813
                     /locus_tag="LP245_002678"
     CDS             <1..813
                     /locus_tag="LP245_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBL1520539.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="LP245_002679"
     CDS             807..1229
                     /locus_tag="LP245_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520540.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            1533..1913
                     /locus_tag="LP245_002680"
     CDS             1533..1913
                     /locus_tag="LP245_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBL1520541.1"
                     /translation="MSEQNQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            1895..2809
                     /locus_tag="LP245_002681"
     CDS             1895..2809
                     /locus_tag="LP245_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBL1520542.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            3049..3738
                     /locus_tag="LP245_002682"
     CDS             3049..3738
                     /locus_tag="LP245_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520543.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFL
                     GCIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTT
                     CYKEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYVKDTKI
                     EEACSDLFGDTNPWFASEEEKKEKQQSVTYERYENLFQQATNMQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(3859..3945)
                     /locus_tag="LP245_002683"
     CDS             complement(3859..3945)
                     /locus_tag="LP245_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBL1520544.1"
                     /translation="MFEQFICPLLVGVCVSLFSYWLNNRNKK"
     gene            4590..5327
                     /locus_tag="LP245_002684"
     CDS             4590..5327
                     /locus_tag="LP245_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL1520545.1"
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEI
                     FTFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDK
                     VNETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKG
                     HWFVKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAY
                     KGNKIGSLQIYFEENIPSITLDNWLEK"
     gene            5356..5877
                     /locus_tag="LP245_002685"
     CDS             5356..5877
                     /locus_tag="LP245_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBL1520546.1"
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKV
                     VLRSGVLQLASNLGNQRLLDRLHEYEQENDKNVYISRKNVVVNELLDKLREENEFLRE
                     QLSLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEEPEEEVLTSVNKENN
                     NAITTEKKWWKFW"
     gene            5961..6265
                     /locus_tag="LP245_002686"
                     /pseudo
     CDS             5961..6265
                     /locus_tag="LP245_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302541.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            6824..>7165
                     /locus_tag="LP245_002687"
     CDS             6824..>7165
                     /locus_tag="LP245_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBL1520547.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2720 a         1174 c         1230 g         2041 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcctttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tctctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgtgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acgtgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaagtagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaacc cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctctaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgaa
     1381 aagcggttat ttgctagcca aatacgtagg tatttggcta gcaaatatag agcttgccaa
     1441 acccttttag tgagctttac tcattgtacc tttttaggta caatggtatt gcgaacgata
     1501 cgtccgtagg acgtactgaa agggtgggac ttatgagcga acaaaatcaa aatttggcta
     1561 gcgatcattc taaaaaatat acctatcgat ccgagccaaa acaaatcagt tttcgagtga
     1621 gcgaatctga atttgcaaag ctgaagcagt cagctgaagc tttgcaaatg agtgtgccgg
     1681 ctttcgtaaa agccaaggca caaaacgcgc gtctggtgac accgaaagtg gcgccagaca
     1741 ttgcccaggc aatcgcgcgc gatttagcca aagctggagg gaatatcaat caaattgcta
     1801 agtggtgtaa tacacaccaa cacgacgttg ctcctggaga cgcccaacgc ttatccgaaa
     1861 acctaaaaat catgcaaaag gagctacaaa agatatggca acagttaaag taagccgaac
     1921 cacttcttgt agtcgtgcaa ttaattacgc tgaaccacga gcaaccatta aaacaggaat
     1981 aaactgtgac gtcgattatg ccaaaagtga aatgaaacaa attcgcatgc tgtatggaaa
     2041 agacgaccgt gtacaggcac acttattgat tcaatctttt cgaccaggag aaattaccgc
     2101 tgaaaaagct aatcaactag gggcagagta tgcaaaaaaa atagcccccg atcaccaaat
     2161 agctatttac acacatacag acaaagacca tattcataat cacattgtca ttaactccgt
     2221 taatctggag actggaaaaa aatttcaagc tcatggtcaa gcatttctaa acaaatgtta
     2281 tgacctaaat gacgagattt gtcttgcaca taacttacca atcactgagc gaggaaagaa
     2341 accagaaaaa cgaaccatgt ctgaaataaa attaaaagaa aaaaatgaac ctgtttggaa
     2401 agacgaaatt cggattgcga tcgatcaaac aatgaaaaac aaaaaaacca gaacctatga
     2461 ccaattttgt aattccctca aaacattggg gattcattgc ttcaatcgcg ggaaaaattt
     2521 cacttacgaa ttgatccaca aaaagaaaaa agtacgatcc aacagactag gaaaggacta
     2581 cgaaaaggag acgattttac atgagctgga cagacgagaa cgaacctata accaacagcg
     2641 aaccaacgag ctacgaagag ctcgagctag cattcgcgaa actgcagaag aagtacgaag
     2701 agaacaacga actcttacgc ctgaacaacc ggaaattaga ccggctcgaa gaaaccatga
     2761 acaacacgtt gaaagaggaa cagaccacca acaagaatta tcgctctaaa acgttaaaag
     2821 acatagaaaa cgaaataaag aaacaacgtg cttttctcgt tccttatacg caagaaagga
     2881 tacaaactac gattgattta caagttaaaa aactccatca agagctatta gaccagcgaa
     2941 ataaggaaca gaaaaaggtg cttattcaac gatcattgga ttttcttgcc cccttatgtt
     3001 gcttagtcct gacactgttc gcattttggt tagtatgggg aggctaaaat ggcattttat
     3061 ttaccctatc tactcatttt tgttagtatt tcaggaagta tttggctcat ctataaaatt
     3121 tttcaaacaa gatattcatt aaaaggctct aaaattcgat ttaagcgatt tttctttctt
     3181 ggctgtatat tttccttgat aatcgtttca agcggcttat tcggcgtttt agagggaaat
     3241 aagcgcgttt ctagaagtat tttattagga aatgtcactc aaaagtatga atcagcgcgt
     3301 gataaaaaga aaaaagagca agcattagca caaaaaatgg aagagtttac cacttgttat
     3361 aaggaaatga acgatatttt tgtgaatcaa gaaaaacgtt tgacggataa aaacatggaa
     3421 aaactcactc gtctttatca aaacttgcca gaaaaacagc aaaaagaggt tcaagacaac
     3481 tatgagcgaa ccaaaaaaga cgtgcaatat gtaaaagata caaagataga agaagcctgt
     3541 agtgatctat ttggagacac aaacccttgg tttgccagtg aagaagaaaa aaaagaaaaa
     3601 caacaatctg tcacatatga acgctacgaa aacctgtttc aacaagcaac taacatgcaa
     3661 aatccgacaa aaaaagaaac cgccttaaac tatctaaaaa gtgtcaagga atggttagat
     3721 cagcaacagc aaaattgaat ttgattgaaa ctcatgttaa actgaatgtg caaatgatca
     3781 aacattagat acacgaaagc cccagagagg tcggattctc tggggctttt tttcaggttg
     3841 atgtcgcctt tactgatttt acttcttgtt tcggttattc aaccaataac tgaataaaga
     3901 gacacaaact cctacaagaa gggggcaaat gaactgttca aacattagat acacctcctt
     3961 ccagtcgcaa gactgtcgga taggcgacaa gttattatac cctacaaaat taaatctgtg
     4021 tggcgatttt aagtatacct tattttcggg ttgttagggc ttgccctgac cgcctgtaag
     4081 gcgcttctcg actagattaa gggagttaat caagaattgt cttagaacgg cttagacaag
     4141 ctctcagatt ctcccacctc ctctttgaac aacggtttta gcaaaggagc cggaggcgac
     4201 tgcgcaggta caatgtgaga gcgtagcgat cacacctttt tagcgcccgt agggagcaag
     4261 ttttctagtt tagaaaaatt cgcgaacctt tttggaggta aaagtaggag ttttttaggc
     4321 gggaaattaa atgtgctctt aagatatact gttagatata ctgttagata tactgttaat
     4381 aataactgtt agggattagc aaccttatgg gagagtaagt attgacatag gtagtggggg
     4441 ataaattgtc acactatggg ggataaattg tcacactatg ggggataaat tgtcacgcta
     4501 tgggggataa atcgtcacac tatgggggat aaattgtatt ttacaccctc ttatgtctat
     4561 gataacataa tttattgagg tgatttttat tgagtaacga tatagttcga tataataatg
     4621 gattaaattc tgtcccttta agaaaattta cccctataga tatggattta ttttggggaa
     4681 tatgttctaa aatgaaaaga aaaggtacaa aagaagaaat ttttacattt aaacaaataa
     4741 aagaattaat tgattacaat ataaatgcac gtggcgaccg ttttgctaat gatttaataa
     4801 aaatgtcaaa aaaaatcatt actttgtctt ttatttatga agacgaaaaa acatatgaac
     4861 aattaaatct gtttcaaaaa tttaaaatcg ataaagtgaa tgaaacatta ttaataaagg
     4921 tttctgaaga atttgaatat atacttaatt caatcggaac taattttact cgtttcgaat
     4981 tagaaaatat gacaaactta aagagtagct acgttaaaga gttatatcgc caacttatgg
     5041 ctcataaaga cagaagatct aaaaaaggtc actggtttgt aaaaatagaa gattttagag
     5101 ctctattagc aataccagaa agttatcgca tgagagatat tgataaacaa atttttgccc
     5161 aagcgaaaaa agaattttta aacgttaatt caactcaccc tgctattttt aaaacttttg
     5221 aaatcaaaaa aattaaagcc tacaaaggaa ataagatagg atctctgcaa atttattttg
     5281 aagaaaatat accttcaatt accttagata attggttaga gaaataataa cctaacaatt
     5341 taggaggcaa ttatcatgca acccaaagaa acctttacaa taaaggaatt atctgaatta
     5401 tttgaaataa gtaggcaagc aatttctaaa catgttgata aattagaccc gtccttatta
     5461 gctaaaaatg agcgtggtta taaggttgta ttacgttctg gagtattgca acttgctagc
     5521 aacttaggta accaaaggtt actagatagg ttgcatgagt atgaacaaga aaacgataaa
     5581 aacgtttata tatcaagaaa aaacgtggtt gtaaacgagt tgctagataa gttgcgtgaa
     5641 gaaaatgaat ttttacgaga acaactttct ctcaaagagc aaaataattc taatatgcaa
     5701 aaattactcg accagcaaca acaactcacc ttgcaggcaa atcaacagat cgaaaaactg
     5761 caagaacagt tacaattagc ttatacggaa gaacctgaag aagaggtatt aacttctgtc
     5821 aataaagaaa acaacaatgc aataacaaca gaaaaaaagt ggtggaaatt ttggtaacaa
     5881 ttaccaactt tccataaaga agaaatcaat ttctatagac tttatctttc taaaaataaa
     5941 aaatatgttt aggtgatcaa atgactataa gtaaagtaat caaacaaaaa agaatagaaa
     6001 aacaactaac tcaagaagat ttagctgaaa tgcttttagt atctaaaaaa accatttcta
     6061 attgggaaaa tggtagaaca ataccagata cagaaaattt aattcaattt gctaagttat
     6121 ttgatttatc actagacaat attttgttag gagaagaaaa agttatgtta aaaaatcata
     6181 caaaaacact aatactatta tttcattttg taattttttt aagtttagtt tttaccttaa
     6241 ttcagtccaa attcttttat tttagccatt caattgccac ttggttatta atattttttc
     6301 taagtttgct attagtaatc aatactctga ttattatttt taataaacat aaaaatttat
     6361 ttcttcatag tgtttttcca attattttgc tgagtttttt atactttgta taaagtataa
     6421 aaaaagactg ctctttcgag cagccagtta aaaaaataat gagagtttat tcttgaaaaa
     6481 gcaacgcgct tataaagcgc taccaaaatt ttatcatatt ttataaaaaa taacaatcca
     6541 gtaaaaaatg actggtaaaa attcacaaag aaacggaaag aagcaactgc agaaaatcaa
     6601 gccttaaaaa aagcttttga cctagaccaa tgaaaaatca caaagtgagc agctatagcc
     6661 cttgatagag gggctacttg gcatagtcga cattatgtta actaacgcta taaataacga
     6721 ttatgttccc aaaacaatat tttatgaact ataacaaaaa tttgttatcg catattgtat
     6781 attttaatta taggtgtata ccacttaaat ttaacacaaa ggcgtgatta ttttgaaacc
     6841 caaaaagaaa atttatctag gtctcctctt ttccttgatg attggaattt ttagtatagg
     6901 aattacaaat acctatgctt cagaaaattc taatttcaat atcaactccc aaccaattga
     6961 agaacaagca attaattttg cgaaaactga ttttgaacac tccataactt caattctttt
     7021 aatggaaaat aacaccgaaa ctgatattaa ctatactctt ggttcgccat ttaaaatgct
     7081 cgatggagaa aatacggcaa atagttctat tttctttcca gtattttcag acgctgataa
     7141 tacgattaaa tatatttata ccgtc
//
LOCUS       DAFEEZ010000100         6643 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000100
VERSION     DAFEEZ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.105"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(1..859)
                     /locus_tag="LP245_002688"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="LP245_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="LP245_002689"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="LP245_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBL1520548.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="LP245_002690"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="LP245_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="LP245_002691"
     CDS             complement(2143..2373)
                     /locus_tag="LP245_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HBL1520549.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="LP245_002692"
     CDS             complement(2603..3421)
                     /locus_tag="LP245_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL1520550.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="LP245_002693"
     CDS             3582..4271
                     /locus_tag="LP245_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBL1520551.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="LP245_002694"
     CDS             4285..5787
                     /locus_tag="LP245_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1520552.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="LP245_002695"
     CDS             5800..6276
                     /locus_tag="LP245_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1520553.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="LP245_002696"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="LP245_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1033 c         1204 g         2234 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttc aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atg
//
LOCUS       DAFEEZ010000101         6466 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.106, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000101
VERSION     DAFEEZ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.106"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(109..564)
                     /locus_tag="LP245_002697"
     CDS             complement(109..564)
                     /locus_tag="LP245_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520554.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(718..1926)
                     /locus_tag="LP245_002698"
     CDS             complement(718..1926)
                     /locus_tag="LP245_002698"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBL1520555.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2038..2370)
                     /locus_tag="LP245_002699"
     CDS             complement(2038..2370)
                     /locus_tag="LP245_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBL1520556.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2518..3393
                     /locus_tag="LP245_002700"
     CDS             2518..3393
                     /locus_tag="LP245_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL1520557.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3475..4056)
                     /locus_tag="LP245_002701"
     CDS             complement(3475..4056)
                     /locus_tag="LP245_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBL1520558.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4062..5321)
                     /locus_tag="LP245_002702"
     CDS             complement(4062..5321)
                     /locus_tag="LP245_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL1520559.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5323..6369)
                     /locus_tag="LP245_002703"
     CDS             complement(5323..6369)
                     /locus_tag="LP245_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520560.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
BASE COUNT         1803 a         1337 c         1102 g         2224 t
ORIGIN      
        1 aaatcttgtc acagtccctt attctgaata aacggtgtgg aagagacagc ctatcagtag
       61 taataagaca catctctttc acagcctcat ttttgcgtaa aaatcgattt attcgaaaaa
      121 ttccccgtat acatcttcta cacgttgatc tggattgatc acgatataca agttacctgt
      181 tttttcgctg atttttgttg attgatattg attgtctaat ccttctgttc ctttatctag
      241 atatgggaag tacacaagat caggtgtgcc atttcggtaa aggatttcca ttcgctcgat
      301 atcttcgtat ttcaatgcgc gattaaacat gcccatttcc agtccgccta ggttgatatc
      361 atgtgtcgca actgcgtccc cttcatggaa gatttcgatt ttaaatccag cacacggatg
      421 gatttcaaca aattcactgc cattgattcg tccaaaactt gttgtgattt gtttgatcca
      481 aagatcgccg atatgacggc ggttgatcgt ccaggtttct ccatttctaa aataaaattt
      541 tagcgctgtc atttctttac tcattaaaaa gactccttta tgatgtaatt tattcttgta
      601 ctacctcagt ttagcacaaa tttatgtaag tggtcacatc ttatgttttt tcttctaatg
      661 acgtatctgc ccactttaag tagccaacaa agctgagcag atacagtcta gtgtttttta
      721 aatcaatttt tctttcgata aaaaatccaa aacctgtttt ttatcatttt ttattctttg
      781 ttctacgacg gctttttcag ctaattgcaa agcttcacta acccacttac caggtttttt
      841 tccagtttct tctagcaaga ttttaccatc tactgctaat tcgcttaatg acttgatagg
      901 taaacgatca taggattctc ctacggcatc catctgaggt gtttcgtcaa aatagatcat
      961 caattcttct acttgcagtg catgtttttt gcctaagaag tacaattcga atggttccaa
     1021 agctccagtt tctcgttgtc gtagtccttg gacaagtgct tgaacgtctt taatcatttg
     1081 gttagaacac ttccacgatt tcaaaaagga acgaatctca ttttctttta gatccagttg
     1141 gctgatcaat aatgcccatg cttggctctc ttctttcaat gggacggatg gtaattcagc
     1201 aaaacgtaaa agtgcttcgc cttcttcttt caaaccggga cagcaaatgt agcactctgt
     1261 ttcaataaat gcatggattc ccgcggcccg ttcatttccc aagagcatct tgatgaattc
     1321 cacatttata cgttctacag atattttacc taatagctcg tggttttctt tgatggcgta
     1381 gaaggtttct tcctctaatt tgaaccctag ttgactgaca aaacgcaacc cgcgcatcat
     1441 tcgtaaggca tcttcatgga accgctcatg aggattgcct acagctcgca agatctgttc
     1501 ttctagatct tgcagaccat cgaacaaatc gatgatttct ccatcttctt tcaaagcaaa
     1561 cgcattgatc gtaaaatctc ttcttttcaa atcttctgcc aacgaacgaa cgaattcgac
     1621 atgatctggt ctacggtagt cctgataagt tgattccgtc cgaaatgtgg tgatctcata
     1681 ttgttcatca ttttctaata ccaacacagt tccatgttcg atcccaatat ctatcgtttt
     1741 tggaaaaagc tgtttgattt cttctggaaa tgcgcttgtt gcgatatcca catcatggat
     1801 tggctggttc agcaagatat cacgaacact tccacctaca aaataagctt catatcctgc
     1861 attctctaat tttttcagaa ctggaattgc cttttggtat tccagaggta attgttttaa
     1921 tttcattttt ccaacctttc ctgcgtgttt cttgtcctga gataaagact cagttgcatg
     1981 gtgactgttt gacaagtccg tttcagagtc ttcaaggcca ggaccacttc atcttgttta
     2041 ctcgtcctta cgctcaaagc gattatggtc tctttgattg aatttttcca tgtttttttc
     2101 aaaaacttca gttaagtcga tattcaatga attagccatg atcatcgtaa cgaataaaac
     2161 atcaccaagt tcttctgcta ccgagttaac tggttcagaa gcctttttgc ttttttctcc
     2221 ataagtgtgg ttgacttctc ttgccaattc acctacttct tcagttaatc gagccatctg
     2281 agctaatgga gagaaatacc ccaccttgaa ttgctggata tattcatcca cttcctgctg
     2341 catactgtat aaagaacgct ttttatccat ctttttccct ccaaaactat cttaccaaaa
     2401 ctttaacgca aatcctagat aagagcaatt gagaaaatcg aatttccatg ctacatttag
     2461 gaaggaattt ctaaatggaa attctgtgaa aatacataat tgaaagctgg aattcatatg
     2521 gtcaaacgaa aaacagtaaa agaagttctt tttatcatta taggaacaag tatttatgca
     2581 tttggtcttg tttacttgaa catcgctaat catttagcag aagggggagt ctcagggatc
     2641 accttgatct taagagcttt atttggtatt gatccagctt atacgacttt attaatcaac
     2701 atcccattga ttttactagg aggaaagatc ctcggtaaac gttccttggc ctatactgtt
     2761 ctaggtacac tttctttgtc attcttttta tggatctggc aaagggttcc actagaaatc
     2821 aatttacagc atgatctact gatcgtttct ctacttgcgg gtttagttgc aggtgtagga
     2881 agcgggatcg tctaccgcat gggtggaaca acaggcggca gtgatattat cgctcggatt
     2941 ttagaacaaa attacggcat cactatgggg cgttccctat tggcatttga tatcatcgtc
     3001 ttacttgctt cattaaccta tatcgacttg aaacgtatga tgtatacgtt gattgtttcg
     3061 tatgttttca gtcgtgtgat tgattcgatc ttagatggcg gatattctgc aaaaggtcta
     3121 cttgtcgtct ccaacaaaag cgaagagatt gcaccactac tgatgaccgg tctgcaaaga
     3181 ggtgtgactt tcctttctgg agaaggcgca ttctctggta attcaaaaaa aatcatctat
     3241 atggtcgtta gctctagtga attaactgaa gctaagagga tcgtccacga gattgacgaa
     3301 aaagctttcc tttcaatcat caatgtgcat gaagtggaag ggcaaggctt tacttatttg
     3361 aagccacaga caagattact gaaaaaacta taagaaaaaa gacaaagata ggctatgagg
     3421 aaagattcca catccagctg acctttgtct tttttagtac tatactattt ttaactaatt
     3481 gttatgttca cttacccggt tacttttctt ttgtgtctgc aaaaggatct ttcggttaac
     3541 ttcatcagat aatttcaaaa aagcatccct atctccatct tctagtgctt gatcgatttg
     3601 agcataaagc atttttagtt ttgcctcttc ttctttttct tgaaaatatc gttcaattaa
     3661 ttcagtatct tcttcactga ctgaagaatc ccaagaagaa aatggattgt cttctaagat
     3721 agatagatat tctcttgtct gccaagcatt ttcgaatata cattccacat ataaaggctt
     3781 tttccaattc aaacggattt catgaaaaat ctggtctgtg tccgtaaatt cttttccctg
     3841 caaaaacaat ttcatgggtt ccccttcaac agatagatca ctgatctgca gtcctcgatc
     3901 cgcaaaattc gccccttcaa caaagtggac attgcttaaa atcgcttcat gattggcaag
     3961 ataattcaag atccaaaaaa cttctcttcg gctaaaagat acatgattga ccatccacgt
     4021 taaaaaattc ttcttttccc gtacatcaat tagcattttt ctcacctctc tgttaggtca
     4081 tctaataatg acagtgcctc catatctcct ggttcaagtg ttaaataata agtcaataat
     4141 tcttgcgctc ttttcagctg cccttcttct cttaagaaaa aggcatactc tttcaagaaa
     4201 tctggttcat gtgatagttc atgataagcc tgttcatagt gtacagctgc aacggtaaag
     4261 tcttctaatt cattataagc atgggctagg ttccattctg cataaggatt agcagtttct
     4321 tccatctgat tgatcacttg tatcacatct tcatatcttt catcatccaa gtaaagatta
     4381 cttaaagtaa gtaatgtttc atcttgtttg tctcctactt ctaaagcttt cagtaaaagt
     4441 tcttctgctc gctgtctatc atgcagacgg aaagcatttt ccgaggccag gtgataaagt
     4501 tcgacttggt aaggattttc tttgattcct tcttctaaca ctgtttgtgc ttcttcaatc
     4561 atttcttctt cttgaagagc ttgtcctaga tatagatata acgattgata atgcggatta
     4621 acttctcgaa gttcttccag atagttgatt gcctgctgat tttctttcaa ttgaagattc
     4681 gtaaaagcta gctggaacag tcgatcatct gtcctttctt ctttcagtgc ttcttctaaa
     4741 ggtacgatag ctgcttcgaa ttctccttgc atacttaagg attgtcctaa acgttcctgc
     4801 atcgagattc ctgaaatttc atttatcccg cttgccaaca atgtttcata aaccactgct
     4861 gcctctttga aacgatcaac tgaaaaatac aattcagcta gcgcaaactg gatcaatggt
     4921 tcatcaggaa gcaacccagc tgcttctttc aattttgctt cactcacttc agggattccg
     4981 ataacttggt acaaatcagc tatcgccaat aagctttgcg gatagtaatc actttgctta
     5041 tccacttttt ccaggtattc aaaagctaag tcgatctcat tatcttcgat tgcaatttct
     5101 gctaacggga tgttcagtcc gtcattttct gggtattggt tgatcagttg ttcaaaaatc
     5161 tgttttgctt cgatcaaaaa gccaatagcc agcaattctt cgcctagttc agctaatata
     5221 tctgctgggt cttcttttaa tgctttttct aaaaagattt gtgcttgtga caagtcttca
     5281 tctgataaag cttgcaacat tttttcgcta tttgtattca tttcaattcc ctcttatctc
     5341 actgacgatt tgttgaaata ccgtcattgt tctcaataat tctttttcgt ttggatgttg
     5401 gtatccgtct attataccta ttttttctaa aacaagtatt tttttgcttt tttctgccaa
     5461 aaaaagaact ttttccaaat actccatctt tgaaatctgt tccagccagt ggattggata
     5521 gccaagcaag tccagccaca caaaaaagtt ttttagttgg aaatcaaaag gatatgcttg
     5581 gagattccac acgaaatgaa acatcattcc taaaaatttt ttcatactag cagaaagtag
     5641 atggccattt tcggtcagat aaaaagcttg ttcaaacagt ttaccataat ttgacaggtt
     5701 ttctgcctct aattgataaa aatagatcat ttcttcgatc atcccggcaa acggccgagt
     5761 cgttaattgc tttttatttg gatagttttt atacagattt tgcaaaaaac gatgatcaca
     5821 aatcattccg caacagataa aagtcaaaaa gtcaatctgc tttccgtcca cctgccgctc
     5881 gctgattgtt tgatcataaa cgatgcgttc tggcagattg atggtttgca gcactacacg
     5941 atttggtagc tgcaaaatcg tccgctgcgg tgttaatgct cggcttagag aacggatcga
     6001 tacagggatc atccatagtg atgaatcaag ggttgtatgt ttttgaaaaa aacctgccag
     6061 atccatgatc ccttcatttc caaatccgat gataaacatg gattgatttt cgggatagcg
     6121 tttgacgaaa tcaagcaggt tctttaattc tgttaaatga ttgcattgag tgttggcaca
     6181 aatataccag tcattgtttg cttgatttgc aaataacggg ttgatcttat ctgcaaacaa
     6241 atcataatag cgctgattcg ttaaaaataa gattggctga tcaatggaaa gttctcttag
     6301 ctgactgact agcgtttctc cgtaaaacac tttcgtcaac gcatcttcta cttgataatc
     6361 aagttccata cgcatccctc ctcttcttat ttttatttta ccattagtaa gcaaattcta
     6421 gaaaagataa gagcaaagct cacctcataa cttggaaata aataaa
//
LOCUS       DAFEEZ010000102         6410 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000102
VERSION     DAFEEZ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.107"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            75..1379
                     /locus_tag="LP245_002704"
     CDS             75..1379
                     /locus_tag="LP245_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL1520561.1"
                     /translation="MLNDINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLS
                     QNSLFLKTCLLYLEEDEPDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPR
                     FTEMERRLLLLNVSYRLGGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILLI
                     GFAISFLRQQVCAVTIDSKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLF
                     NLCNYGFHSYQLIAEDFQQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIH
                     LMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVI
                     ELSGILRLTKEHLTIYIVTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQ
                     QSSNRVLCERTLYTPDAVQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1471..1836)
                     /locus_tag="LP245_002705"
     CDS             complement(1471..1836)
                     /locus_tag="LP245_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBL1520562.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1833..2198)
                     /locus_tag="LP245_002706"
     CDS             complement(1833..2198)
                     /locus_tag="LP245_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBL1520563.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2390..2638)
                     /locus_tag="LP245_002707"
     CDS             complement(2390..2638)
                     /locus_tag="LP245_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520564.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2637..2765
                     /locus_tag="LP245_002708"
     CDS             2637..2765
                     /locus_tag="LP245_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBL1520565.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2822..4516
                     /locus_tag="LP245_002709"
     CDS             2822..4516
                     /locus_tag="LP245_002709"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBL1520566.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQ
                     EEEHVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4520..4639
                     /locus_tag="LP245_002710"
                     /pseudo
     CDS             4520..4639
                     /locus_tag="LP245_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4616..4789
                     /locus_tag="LP245_002711"
     CDS             4616..4789
                     /locus_tag="LP245_002711"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520567.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKVV"
     gene            5167..6300
                     /locus_tag="LP245_002712"
     CDS             5167..6300
                     /locus_tag="LP245_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBL1520568.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQNGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYE
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
BASE COUNT         2121 a         1222 c         1169 g         1898 t
ORIGIN      
        1 gtgggcaatt ctatgtaaat aaagaagtca atctagaaaa gctctccaat ctcctgcatg
       61 tttgcaaaac cactttgctc aatgatatca ataacataaa aaaagaattt gaagaacaga
      121 tcgcttatac acatcgggaa aaggaccgtt acactttata tttttcagaa catatacctc
      181 gatgcaagat catgcagcaa ttgtctcaaa attcgttgtt tttaaaaact tgtctgcttt
      241 atttggaaga agatgaacct gattatcttc aattaactga atgtgaattc atctctgtca
      301 gcaaagctta ttcattaaaa aaacaagtat tagcttattt taatgactgc gggatcgaaa
      361 tcgaccgcta ctcccctcga ttcactgaaa tggaaagacg tctgctgctt cttaatgtgt
      421 cgtatcgttt aggcggtttt aattcttggg agctacctga atcgtttttt gaacgtgccg
      481 atcgtttcat tgaatccgta acggaaaata gtggcagatt ttatgataaa gaaaataaag
      541 aaatcttatt gattggtttt gctatcagtt tcctacgcca gcaagtgtgt gctgtgacaa
      601 tagattcaaa atttatcgaa gaaatcaaaa aacgtcctat ttacaattat gtcgaatcag
      661 catgggaaaa cactgatttc caaacctatt ataaaaaaga agaattcgcc tttattttga
      721 cactattcaa tctttgtaat tatggtttcc attcttatca gttgattgcg gaagactttc
      781 aacagctaca ccaagtgttt attgacaata ctcccgaaat aaaagaacta gttgctacct
      841 ttgaatctca cttcaatcaa gaattattcg gaaaccaacc attcgaacgt gcgctgattc
      901 atctgatgcg ttcggcttgg gataactatc aattattcat gccagaaaaa ttttatcttc
      961 taaatgagga acagacaaat ttatataaag aagtccagac aattttttcc agctggtcca
     1021 gccagttacc ttatgatcta cggttgaatc ctaattgcat gcgggctttt gtgatcgaat
     1081 tgagcggaat tctccgtctg acaaaagaac atctgactat ctatatcgtc acaaattcgg
     1141 atgttcatta tctgatttat cgggaagcct tggaagctgt aactactttc gattttcaag
     1201 ttgcaccaac aatttattca agtatatctg atataaagaa gtatgcgcag cagtcctcaa
     1261 accgggtatt atgtgaacgt acattatata caccagatgc ggtccaatat gaaaatatta
     1321 ttcctatttc gatcaatacg atcgatcgag ctatcatttc agctgtgcaa aacaaataag
     1381 ggactgtgac aaaaatcatg tcacagcctc ttatttgttg aagatgccca tttctgtaac
     1441 aatctcttga tacacatcag gctcacaacc tcacttattt tggacatcta cgggtccgat
     1501 ctctttattt aaaaaataag aaatgatggt tcggataact accaacgccg ctagttggaa
     1561 aatatcctgc aaggtaggtt tgataatcga ttcgatgatc ccagctgaaa caagaatttc
     1621 caaacttaga agtatatagc ctcccaacat ctttttaata gcattgttct cgctgactcg
     1681 gtcgctttgc acttttgtat ggacaaataa atatttcaaa aaatccttga ttgatagaca
     1741 aacaccccaa accaataaac agatagcaaa gatatcaagt cccagtacaa gtttttcaaa
     1801 atatggaaga agaaactgca tcaactctgt cgtcatccta cctctcctct tctttgtttt
     1861 tctttgtctt ctatttcctg attcaagaaa taagaaatga ctgttcgaat gataataata
     1921 agtgcaagct tcaaaatatc tgtccaagtc ggcttgataa ctgactcgat gatatcagca
     1981 acgactagta cttccaagct taacaaaata taacttgcta gcagttttct tgtatctgca
     2041 ttacgagtat tacgttctgc atagtttttc ttgacatgag accaatcaaa aagtttgaat
     2101 agaacaagaa cgatcccgac aattaagata ccgatagaac aaatatttaa aatagcaatg
     2161 atccattcta gaaattcaat taaatttgag cgaaacatat acgctaccta ctttctttta
     2221 atttgttcct attcttttat tgtaaaagaa agttaccttg ttcgtctatt taaaagttgt
     2281 tctaatgata acggttcgct taaatttttc tttttcactc tccccttttt ctccctccat
     2341 ccataaatcg tggaagtatc caaaacaacg tagcaagtta aaataaggct tagtccgtca
     2401 tcagcttttc aaagaagcac tgtctcggtg ctttttttgt acccaaattt ctaaaaatag
     2461 aaccatacac ctcctcaaat cttttcttct tacctaccct atttttattt acaggaaaat
     2521 cagacacttc ttcttttttg tcaaaatttc ctttttcttc tcgtcctatc atttggcatt
     2581 ctaataaaaa cgaactatcc ttggatatag aaagagaaaa caaggaggcg tttttcatga
     2641 gtaaaaaatt aatcaaagtc ggcatcggtt taggtttgct tgcccttggc gctgcatatc
     2701 taggaaaaaa gacaggacta ttcgaagatg acagtcattt atatgatgaa ttcgaatcaa
     2761 tctagcatcc tatttagttg aatcactacg gacatacttg gaagacattg gaggaatcac
     2821 aatgagaaaa agtaaagcaa taatgattgg tgccggtatt gccaatatgg cagcggctgt
     2881 ttatttgatt caagaaggca aatggaaagg ggatcagatc accttttatt cattggatga
     2941 tcacggttca aatgatggtg caccgaccga cactgtagtg gatgaatatt ggaataaaaa
     3001 ccatccatta gaaaaccaaa aaggctatat tgctcgaggc ggtcgcatgc ttaattaccg
     3061 tacctatgta gatttgatgg atctgttaag tcgaatacct tctgttactg agccagggat
     3121 gactgctgaa gaagatacga gagattttga tgcaaaacac cgaacctttg acaaagcacg
     3181 tttgatggaa ggtggcaaag gaatcattga tggcggaaaa ctgggattca ataataaaga
     3241 ccgtattctt ctgactaaac tgattgctat gcctgattca gaagaagaaa aactagacaa
     3301 tatcactatc gaagaatatt tcaaagatga tccacacttt tttgaaacaa acttctggtt
     3361 tatgtgggaa acaacatttg ctttcagaac acgtagttct gctcaagaat tgcgtcgcta
     3421 tatgcatcaa atgatttatg aattcactca aatcgaacat ctagtgggcg tcaatcgaac
     3481 acgttacaat caatacgaaa gtattatgct tcctttgatc gagtacttga aagaacaagg
     3541 atgcaaaatc attttgaacc gccgtgtcac tgactgggaa ttcaaagaaa caccgatgca
     3601 agatgaaatc actgtgactg gtttgaaaat gaccaataca ctgactcaag aagaagaaca
     3661 cgttgtggtc gatgaagata cagcagttat tttcactaat gggtccatta cagattcagc
     3721 tactttagga gattacgaaa caccagctgt agaaaatatg gattatggtg cagcttctag
     3781 tctctggaaa aaagccagtg aacgtttcta caacttggga aatcctgaca aattctttgc
     3841 tgatcgagat gcaagcgaat gggtcagctt taccctgacg acgaaaaacc atttgttgtt
     3901 gaatgaaatc acccgtatca cgactcaaga accaggaaat gccttgaatt catttatttc
     3961 aaccacaccg atcacgccgt taggccaaaa agatgtcaat atgtctatcg tcgtgcatca
     4021 tcaaccgcat tttacgtctc agaaaccaaa tgaaacagtt atttggggtt atttccttta
     4081 tccaagacga cgtggcgaat ttgtggataa acagtatatt aaaatgaatg gaaaagaaat
     4141 gctagaagaa ctgattggac aactttcaaa agtagatcct ggaccagtga atattcgtga
     4201 aaaagaaaca gaaattttcg acagcgtaat aaataatatc cctgtctata tgccttatgc
     4261 ttccgcgttg ttcaataatc gtgccaaaag cgatcgacca aaagtcattc ctaaacattc
     4321 gaccaatctg gcctttacag gagaatttgt cgagcagcct tatcagatga tctttactga
     4381 acaaagtgct gtacgttctg gagaaatcgc tgctttccat tttgcgggta tccctatgtc
     4441 acgtcttgtc aaaacaccgc gttacgacaa agatattcct actctagctc gtgccgcaaa
     4501 aaaaatgttt gaataatcaa gaggttgtga aaaagctgcc ctgcatcaag taataagaac
     4561 aaccaggcta aaacagcttc ttatgttttt gatttggttg gacttattac cgcagatgca
     4621 agcttttgaa caccgtttac caagaggttg tgaaaaagct gccctgcatc aagtaataag
     4681 agcagccaag ctaaaacagc ttcttatgtt tttgacttgg ttggacttat taccgcagat
     4741 gcaagctttt gaacaccgtt taccaagagg ttatgaaaaa gtcgtttagt ttcgagtatg
     4801 aagaaaaatt ttgtgaaaat ggttcctcac gtttttgcat aaatttgact taataccgag
     4861 aaactgatcc cttctgtcat aacctctttt tatttatgtc tgtttctttt tgaaaacaac
     4921 cattttttca acgtttactc tcttgccaat ccaacatcat ctaacagata caactatttc
     4981 aatgattacc attacactaa aaaatcggaa actcacctct ccgaacacaa atacataaga
     5041 ctatagaatg tttcatttaa gaaaaaaagc gtttcattat caaaaaggta agatctcctt
     5101 taaaatgaaa ttatctgtag tactaataat gcagacaatt ttatgaatct gaaaggagca
     5161 tctccaatga aagcagtcac ttggcaagga aaacagaaaa tggaaatcag aaacgtagat
     5221 gatccaaaaa tattagaacc aacagatgca atcatccgta tcacagcaac agccatttgc
     5281 ggctccgatc tgcatcttta ccatcatggt gaagcagttt tggaaaaagg gtatgttgta
     5341 ggacacgaac caatgggaat cgttgaagaa gtgggatctc aagttcaaac attgaaaaaa
     5401 gggcaacgtg tggttatccc ttttaatatt agttgtggtc attgtcattt ctgcctgaat
     5461 cacatggaaa gccaatgtga tgaatcaaat ccagatcagt tatatggcgg gcttttcgga
     5521 tttggcaagt tgaacggtaa tcattggggt ggtcaagcgg aatatctaag agttccttat
     5581 gcagactcta cttcatttgt tgtaccagat aatgatcttc ctgatgaaaa agttttattt
     5641 ctatcagata ttttgcccac agcttattgg agcgttgaaa acgcaggagt aaaaaaaggc
     5701 gatacagttg tgattctagg ttctggtcca gtcggtctat tcgctcaaaa attcgctgtt
     5761 atggctggag cagagcgcgt aatcgcagta gatccagtac agcaccgtct agataaagcg
     5821 gctaattaca atggggttga aacttatttc ttagaagaca cggcacaagc tggaacagaa
     5881 ttgtatgaac tggctaaagg tggcgcagat gtcattatcg attgtgtagg aatggacgga
     5941 ttagagcctg tcaaagaaaa agcgaaaaat ttagtaagct tacaaaacgg cacaatctct
     6001 ccattacaga tggcatcgca agctgtcaaa aaatttggaa cagtccaagt aactggtgtt
     6061 tatatgactc cagcttcttc ttacccgctg caagaatttt ttatgcggga tatcgctgtc
     6121 aagcatggac aggcaccaat tatccatcta atgccaaaaa tttacgaaat gattgcagaa
     6181 ggactattcg atcctacaca aatcattact cattcgctgc cactatcaga agcagcacaa
     6241 gcatatgaga tctttgacaa aaaagaagat aaaaatataa aagttgtttt gaaaccttga
     6301 attcagtaaa aaatacaggt gattttcttt atgcccaaaa tcaaacgaaa tacccatgag
     6361 atcgaaatag gaaaagaaga agatatcgaa atacgaggac gtcgcttccg
//
LOCUS       DAFEEZ010000103         6266 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000103
VERSION     DAFEEZ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.109"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(94..666)
                     /locus_tag="LP245_002713"
     CDS             complement(94..666)
                     /locus_tag="LP245_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1520569.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(673..1335)
                     /gene="rpe"
                     /locus_tag="LP245_002714"
     CDS             complement(673..1335)
                     /gene="rpe"
                     /locus_tag="LP245_002714"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBL1520570.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            complement(1351..1866)
                     /locus_tag="LP245_002715"
     CDS             complement(1351..1866)
                     /locus_tag="LP245_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HBL1520571.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            complement(1868..2152)
                     /locus_tag="LP245_002716"
     CDS             complement(1868..2152)
                     /locus_tag="LP245_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL1520572.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            complement(2186..3514)
                     /locus_tag="LP245_002717"
     CDS             complement(2186..3514)
                     /locus_tag="LP245_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBL1520573.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            complement(3528..3983)
                     /locus_tag="LP245_002718"
     CDS             complement(3528..3983)
                     /locus_tag="LP245_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1520574.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            complement(3986..5932)
                     /locus_tag="LP245_002719"
     CDS             complement(3986..5932)
                     /locus_tag="LP245_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL1520575.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
BASE COUNT         2060 a         1205 c          875 g         2126 t
ORIGIN      
        1 attattaagt tatgtctaat caaataaaaa aaccattctc atatttgctg aataattagc
       61 atttagagaa tggtttttta tctttaaaat ctactactca aaatctgcat gtcgagcaaa
      121 catcgtttct gagctttcac ctgttttatc cattaaagat aacactaaac tatcaaaggt
      181 gagaaatgct aattgttcaa aacttgaacc cataggttgt gaaaaagtat cttcttctcg
      241 ttgattttca tctttggtaa tacctggtaa tacaagaaca gaatctgcta attgaccaat
      301 cgacgagtct tttttcatgg taactaaagc aatgcttaca ccactttgat ttgctttggc
      361 cgctaaattt tttaaactac ctgtttcacc tgagccagaa cagataatta ataaatctcc
      421 aggttgcgaa tgtggtgaac taatttcacc gacaaggctg actgaaaaac ctaaatgcat
      481 taagcgattc gtaaatgctt gcatggcaat tccagagcgt cctgcaccag ctagaaagat
      541 gtgtttagct tgaacaattt tctcactaaa ttgttctaac tctacagaat taatacgttt
      601 tgagttattt tgtaattcta agataatcgc ttctaaatag tttttatttt ggtctttatt
      661 ggtcatgatc ttttacttca cttcctctaa tgattgattt agtttatcaa tttgttcttg
      721 cggggtattt ttcccattga agatgaaacc gcctgataca aaaatatccg cccctgcttt
      781 agaacaaact ttaatcgttt gattatcaat cttgccatct acttcaatat catacgtata
      841 atcattttgt ttgcgtatta catctaactg ttcgatttta actactgtct cttgaataaa
      901 atgcttattc tctgttcctg gattgattgt cattactaat acttgatcga ctaaagataa
      961 tactggttca ataaaactga ctggtgttgc aggattaaaa gtaatcccta cttttgctcc
     1021 tgcttccttg actaactgaa tgaccttcat tgcgtgtttg gtagcttcaa tgtggaaggt
     1081 aacaatatct gctcctgctt ctacaaatct tgtgacaatt ttttctggtg tatcaatcat
     1141 caaatgaaca tcaaacacaa cgtctgttag tggacgaata tctttaataa cacttggtcc
     1201 aaaagccata tctggtacaa aacagccatc cattacatca atatgcaaat aatcaacatt
     1261 cttttctttt aagatttcaa ataactcttt aacttctgcg ataggtgcat ttaacaatga
     1321 tggagcaatt gtcattctct attcccccgt ttattctccc ataatcatga gattgattgt
     1381 tctagttcgc tctcttagtt gatcccaatc gacaaaatag acacggccca tttctcctaa
     1441 taaaagttta ccttcttgaa caattaaagt cattgagttg gttccataaa tagatgaacg
     1501 taaatgtgca tcggtattta gcatgaccca tttttctgca gggtaattgg gatcagataa
     1561 tcttgttcca aaatcaatgt gttttggccc cggactgttg tattgatttt cactcgtcat
     1621 ttttggaata atcgtttcca ttacattgtt gatgtctaca tgtaaataat catcaccaaa
     1681 aaagtttgtg tcatgcatcg tttcttcaaa aaagagtgag caagttgtat gcgggctcga
     1741 aattactaac attccattct caatacctgc tgtatcaact gtatctaaaa gttcttttcg
     1801 aatatcatga tacgaaggac gccctgaaac tgtttcaata gtcaaagtgt catgatgaaa
     1861 acgcatatta aacacctaat ctttctttta catctgcata aatggcatct gtaccaatac
     1921 ctgttaataa gcccaagcca ttcgttactt tagctttaat tacatcaggg acaattgttg
     1981 tacttactac agcatcatat tcatcaattt tatttagctc atcagcaatt ttagattgat
     2041 aaattttcac ttgatctgtt aatccttctt cttccaacca ttttgataat tttgctactg
     2101 caattgtaga agtagcatga cctgctccac aaataactaa taattttttc atattgatct
     2161 cttctttctt attttaattt tatgattaag ctttcttcac tttgttcatg tagatagaag
     2221 cacctactaa aacaactcct aatccaccta ttccaattac accaaagtaa gatgctaata
     2281 aaacaaacaa ccctactggc cataatccac ataacaacat agttactaat cctgctgtcc
     2341 ccacatcgaa acttgctaat gtaaacacat cagtgataat tggtgccaac catgttgcca
     2401 tatataatgt tgtaacaaca tacaacgaac atcctactaa tgatctcaca atatttcctt
     2461 taaaataagg aatcattaaa cagatggcga aagcaaagaa tgctaaatct ccaaaaggta
     2521 atactttatt tcctggaaga attagtgcta gcaataatga gattggtaca agcaatagag
     2581 aagttgacat aatagttgga tgacccacag ttaacgctgc atccattcca atgtttactt
     2641 ggcgaccatt taacttttta ttcgtaaatt ctttcgccgc ttctgcaatt ggcattaaac
     2701 cttccataaa cattgctacc attttaggca taatcttcat cactgccgca gtcataattc
     2761 ctaagtttcc aattcctgct acgtcatagc ctgccataat acccactaca ataccgataa
     2821 ttaggccaat aacaactgtg tcacctaaaa caccgaaacg ttttgttaat gtttctgcat
     2881 ctgcatctat tttattaaat ccaggaatac gatcaaaaac ccaatttact ggtttggcaa
     2941 atagtactcc tgataatccc atcatatgtg tgatagagat tcctggatag ccgaaaaatt
     3001 cgctaacagt tttttgtgta cgatctgcta agaaccattg taaaattact gcgacaatcg
     3061 cgccaattaa gccaaaccaa aagtttcccg taacagattg agtaatcata cctaggaaaa
     3121 ttgcgaacca aaagttccaa atatcaacat tcaatgtttt tgtccaaccc aaaaccacaa
     3181 atatgaagtt aagaattaat gaaattggaa tcattaaaat tcccaatgat gtagagtaag
     3241 ccaaaggtcc accaacacct acgccaatat ctaggatatt caggccacca ccgtattgtt
     3301 cccccatttg ttgaattgct gttcctaaac catctgataa taaacttaaa actaatccta
     3361 aaccaataga accgatacca acagtaacgc cggaaacaaa tgctttacca ggttttaatc
     3421 caaataatat cccgattaca aaaataatca gtggtaaaaa gacgtttgac cctaatccaa
     3481 taaaccattc aaaggcattt aatacaatat ccatctctct attcctccta ataaactcct
     3541 gcagaatgta ctaactcaat aaatgcttct ttcgtggtac atgcaagtaa ttcatttact
     3601 ttttcttcat tttgaaatag gctaactaag ttttgtagtg tatcaatttg ttcatgaggt
     3661 tgtgacattg ccaacataaa gactaaacgt acaggtattt catgagattt atctgtcata
     3721 tctgaaaata ccagtggttc ctttaatgag gcaaaacaga tttgagagct atttacatgt
     3781 gcggaatctg tatgtgggat agcaaaccca atttgattta cttctaatcc agttggaaat
     3841 tcttgttcac ggttggtgat accttctaag aaactatctt tcacgcaacc agcgtttttt
     3901 aattgttcag acattacttg aaacaattct ttttgatctt tcacttctaa ttgaaataaa
     3961 cataattctt tatctagata catttttatt ctcctttttg ttgaaaaatt cttagtaatt
     4021 tttcgctatc atgaacttgt aacaagcgat cgaccatttc tttttgccca ataaattggt
     4081 aaagttcttc atatactcct ctaatctcag atacatcttc ttcagctaaa ctaaccataa
     4141 tgactaattt gacttttcga tcgccccaat taatcgcatt ttttaatgct acaataaaaa
     4201 tgttggattc aatgaccatt gatggattcg catgcggtaa agcaacacca ctttctaaat
     4261 tagtattccc cattttctct ctagagaaga tagaagcacg aaactcttca gtaactaatg
     4321 aattggcttc tagttcggaa atcatcaaat ccaaacattc ttctttgctt tccacctgta
     4381 ctcctgtttt tactaaagat gattgaacaa atttagatat ggtgggaact ttaaccgctt
     4441 taggaatcag ttcattttga ataaatcgcg aaggttcttc tattaaatat ttagtataag
     4501 cttccataat attcatataa tctgttttac ttaccaatgg agataccctt actaagggta
     4561 taccacctgc atcaaaggaa agagaggaaa taatcaaatc aacttcccca atttcagcta
     4621 aatgaaactt atctaaagtt gatatttcta cattatcttt tgctggtaaa aaccgtcgaa
     4681 ctttattgta aattaattgc gcagaagaaa taccgtattg gcaaataatg atgatattat
     4741 ttgctttgga ctgatcttca atagcaatct gaaaatgaat caaaattaag gaaacttcat
     4801 cgtccgttaa agtcacatca aattcttctt caaggatgga catggcgtac catactatgc
     4861 taaagagttc tgaatattga gatttgatat tttctaataa cggattttga attttaatac
     4921 ctttttttaa acgaaggacc attgctggca catgatacaa taaggattga tataatcgat
     4981 cattttgagt caaatcaatt ttttcaatct cactcattct ttcaatcaat ttatgaacgc
     5041 tcatagcgta ctcttcattg ctggttttta aattatttgt cacacgatgt gcaaatagtt
     5101 gacgacatag atattcttta tctgcgtcat aaaatggaag attcaatttt gccttcaatt
     5161 cttcaattaa accatttgcc acaatgtacg tttccatata gcgaatgcta ttgaagagga
     5221 attcttcttc aacagttaaa tgatgacctt tcagtaaacg gttacattgg ataactaaag
     5281 tagaaatcaa tgaccgaaca tagtaatcag aaaccttttc agtcagttca ctgtaatcat
     5341 tgaatagcaa atcatgaatg acactaataa cttttgaatc aaacaacata tttaaaactt
     5401 gaaaaaatgt ttttgattcc atgtcattcg cataatagaa tacaagttgc ttgattgctc
     5461 gttgaattgc ttgttcatta ccagtaaaac taattccttc tgcagatgac tgcaacttaa
     5521 cttctccact gccaataatt ttattgataa ttctcaggtc attgtataac gatgttttac
     5581 taaccataaa actttgagac aaatgagtta aagaaacagg cttatcacca aacaaaactt
     5641 ctttaatgat ctcgacacgt cttttttctg gagaataaat atctttttca agataatttt
     5701 ctaccgatga aatcaaatgt tcaacgtttt tcctatcacc tatgagtttg atacccaaag
     5761 aaggtaatcg ctcaattgtt acttggtaat taactacata atcttccaac aattcaatat
     5821 cttgataaat ggtcttggtc gacactgcca atttatcact aaaaaaagaa gcgggtttaa
     5881 agtcttcttg tcgacttaat aattttaata aatttacatg tctttcaatc aaacttgttc
     5941 acctcttaac gctagcattt gttacctctt ttcattattt attctagcac tggaaccccc
     6001 ttccctcaat tacatctatg tcaataatac ttgtggaagt ttgttgtaaa ggaaatccaa
     6061 ataatcttaa aaaatgagaa acaaaaaagg agaaatcctt aaaagagcta agatattcca
     6121 atagaaaata ctccttatta tggaagtaat atgaaatatt acaattgaaa aataaaaaca
     6181 atataatggc gtcactaaaa ttcgtatttt tttattataa tataacttaa ttacaaatgc
     6241 tcatctatga acaattgagt cctaat
//
LOCUS       DAFEEZ010000104         6195 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000104
VERSION     DAFEEZ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.110"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            127..579
                     /locus_tag="LP245_002720"
     CDS             127..579
                     /locus_tag="LP245_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520576.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="LP245_002721"
     CDS             593..1282
                     /locus_tag="LP245_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520577.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..3758
                     /locus_tag="LP245_002722"
     CDS             1407..3758
                     /locus_tag="LP245_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBL1520578.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3838..4233
                     /locus_tag="LP245_002723"
     CDS             3838..4233
                     /locus_tag="LP245_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520579.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4558..5175
                     /locus_tag="LP245_002724"
     CDS             4558..5175
                     /locus_tag="LP245_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1520580.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5216..5515
                     /locus_tag="LP245_002725"
     CDS             5216..5515
                     /locus_tag="LP245_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBL1520581.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5549..5716
                     /locus_tag="LP245_002726"
     CDS             5549..5716
                     /locus_tag="LP245_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL1520582.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5845..>6195)
                     /locus_tag="LP245_002727"
     CDS             complement(5845..>6195)
                     /locus_tag="LP245_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL1520583.1"
                     /translation="QAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKT
                     EHRTVKYLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGF
                     SVSTEIKVLMGITA"
BASE COUNT         2127 a          853 c         1250 g         1965 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttattcaatt tcaagaaaat agaagtaaac ttaattaaga atcgtttact atttaaacag
     3781 tgtccttttc ctttttaaat atatacgata aaataagtat atgaattgta aaaggacatg
     3841 atgattatgg aagaaataga atggaataat ctgactcaaa ataataaaaa taattctgga
     3901 tgtggaatta tctttatgtt tgttatagtt ttgggaatag tagtactttt aataactgtc
     3961 aagatagtag attactttgc gaatactcct gaagaacaaa tacagagaaa acttcctgag
     4021 tttgaaagag taccacctta tgatccaaga gataattcat ttcaagtaaa aaaattaaaa
     4081 gagtctccaa atgaaatgtg gtttgaagtt acagttgaat caagcgactt caaagaaaaa
     4141 aagaaagaat acaattatat tgtaaaggca aaagtatcaa aaagatttat ttttaaccct
     4201 aaattagaaa tatatagtgt tgtaatagaa taatagtgtt aaaaaaattg taaaagttaa
     4261 agaagtcaaa ttctgatgtg aaaaataaaa tataccatgg aagacataaa agaaaaactg
     4321 gataactagt ttatttaatg gcagaccgtt aaggcctgcc atttttatgt attttagcgg
     4381 aataaatata atcatgcggg agtgtaaact tactgtttca aaaagtatac tttttgacat
     4441 gccttgattt tctttgttta tgtatggcat aataaccaca taatacaatt tgaaacgttt
     4501 ctgatttaat ctgattgttt tgaaacaatt ttagtgaaaa aagggtagat aaaaacgatg
     4561 agaaaatttt tttatatccg ggtcagtagt tatgatcaat cgatcgaacg acaactgatt
     4621 tccgcgaagg aattaggaat ccctgaagaa tatatatttg tagaaaaagc cagcggcaaa
     4681 gattttaaac gccctgaata tcaattaatg aaacggatgt ttcgaaaagg agatttactc
     4741 tatctacaat cattagatag actaggcaga aataaacaaa tgattttaga agaatggcga
     4801 gaattaacta aggaaaagca gattgatatt tctgtgttag acatgcctct gttagatact
     4861 gctagttaca agcaactaga tgggttagag acgcttatct ctgacttaat tctgcaatta
     4921 ctcagctata tggccgaaga cgagcggaaa cgaattaata gccggcaaag agaaggcgta
     4981 gaagctgcga aacaaaaggg tgtaaaattc ggcagaaaga aaattgcttt acctcctgaa
     5041 tttcctgcga tctattctga ctggaaagca ggaaagataa ctgcagtcta tgctatggat
     5101 caattgggca tgaaacgaaa taccttttat cgacgggtga aagaatatga acataccttg
     5161 caccactttt cttgatagat ataacagcta ttagacggga agggagagtt tgaaaatgga
     5221 cttaacgaat caaagggtcg tttttactgg aacgctgcag caaatgacac gaacccaagc
     5281 catcggtttg gttcactctt taaacggcca ttgtcaatca agtgttactt caaaaacaaa
     5341 tttcctggtt tgtggtcagt attctaagtc gttgtttgat gattctctct atacaaaaaa
     5401 ggaacaaacc gcgcgggact tgattgcgtt aggtcatgag attaccattt tatcagaagt
     5461 cgaattttat gcgttaatta gtcaacagtt gaaagaatgg caacggtatt tataatcgtt
     5521 agtaaaattt acaaggagga aaatttttat gaagcgaaaa tcttatgatc gttggggcat
     5581 tgaaataact agttttaatc gaaatattgc ttttcacgtg gagtgtgact gtggggaatt
     5641 agcaaaaagt gtttatcaaa aaaattactt ttactgtcct aaatgccatc gccgatacgg
     5701 ggtacatgga acatagaaac gaaatagtgc ggtagaaaag cgaatgaatg tagtatattt
     5761 ctacaaatca ttcgctttct ttattttata ggttctgttg cgaagtttga aaatcaaacg
     5821 cgccctctct gaactccaaa tatcttaggc tgttattccc attaatacct tgatttcagt
     5881 agacaccgaa aagccgaaga gcgttccatt tcttcggttc tttttatata ttcctcgaat
     5941 ggtctccatg cccttaatcg tggaagaggc tgtacggaga ctttgataaa atttatttcg
     6001 tcgtttaata ggtcgatggt cttgttctat taaattgtta agatacttca cagttcggtg
     6061 ctctgtctta gtatataaac ccacactctg taactttcta aaggcggagc caagagaagg
     6121 tgctttatcg gtcacaattg ctttcggctc accaaactgt ttatggagtc gttttaagaa
     6181 agcataggct gcttg
//
LOCUS       DAFEEZ010000105         6136 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000105
VERSION     DAFEEZ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.111"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(207..1169)
                     /locus_tag="LP245_002728"
     CDS             complement(207..1169)
                     /locus_tag="LP245_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL1520584.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="LP245_002729"
     CDS             complement(1171..2610)
                     /locus_tag="LP245_002729"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBL1520585.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="LP245_002730"
     CDS             2795..4741
                     /locus_tag="LP245_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBL1520586.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKINGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..5877
                     /locus_tag="LP245_002731"
     CDS             5005..5877
                     /locus_tag="LP245_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL1520587.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1947 a         1055 c         1083 g         2051 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttaatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggga ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc
     5281 atgaaaaaag aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat
     5341 ggtgagtatg tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt
     5401 acgggtgttg gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca
     5461 gaaatggggc atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca
     5521 tttcatggca actgtttaga agggatggcc gctggacccg ccatcgaaaa ccgcttaggg
     5581 aaaaaaggac aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt
     5641 gctcaatgtg cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt
     5701 ggtgtgatga aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc
     5761 aatgggtatg tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac
     5821 aacgctggaa cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg
     5881 aaaaaaggct cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat
     5941 aaccagttag gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat
     6001 gagataaatt cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt
     6061 gcaatagttt tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat
     6121 atatctttgc ttcttc
//
LOCUS       DAFEEZ010000106         6131 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.112, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000106
VERSION     DAFEEZ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6131
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.112"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(63..1268)
                     /locus_tag="LP245_002732"
     CDS             complement(63..1268)
                     /locus_tag="LP245_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL1520588.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            complement(1291..1444)
                     /locus_tag="LP245_002733"
                     /pseudo
     CDS             complement(1291..1444)
                     /locus_tag="LP245_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(1447..2832)
                     /locus_tag="LP245_002734"
     CDS             complement(1447..2832)
                     /locus_tag="LP245_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBL1520589.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(2861..3247)
                     /locus_tag="LP245_002735"
     CDS             complement(2861..3247)
                     /locus_tag="LP245_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1520590.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(3263..3577)
                     /locus_tag="LP245_002736"
     CDS             complement(3263..3577)
                     /locus_tag="LP245_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL1520591.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            complement(3930..4409)
                     /gene="rlmH"
                     /locus_tag="LP245_002737"
     CDS             complement(3930..4409)
                     /gene="rlmH"
                     /locus_tag="LP245_002737"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBL1520592.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            4837..6126
                     /locus_tag="LP245_002738"
     CDS             4837..6126
                     /locus_tag="LP245_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBL1520593.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVMMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
BASE COUNT         1773 a         1243 c         1154 g         1961 t
ORIGIN      
        1 aggttttgtc caaaattcat aaaaatgttc tcctctctat attcaatgaa tttgtatttg
       61 agttattttt ttgttgttat cacgtcctgt tcttttactg actgttgctt caaaatctgc
      121 ttgtgtcggt ctgtcagttt cgcatggtcg agaatgtctt ttacaacctg cgtctggttg
      181 atttcatcaa gtttaatcgc aacctttaag gtcggggcaa cttgatgaga tagccagttc
      241 agcgtccttt ggaaggagta aggctctggt tttgtggtta gttttaatcg ttcacgattg
      301 ttcccaataa accaagccca ttcttcattc agtttccaat cagaacgagg tttggaatcg
      361 tctttatcta caaaacggat ataccgattg ataattttaa aggcggtatg ctctggattg
      421 tcatagacga gtaaatcacg gactgcataa taggcacgct catttttcaa tcgaatctca
      481 aaacggtttt ttacttctgc gtcttcaatg ggaatatcat ttttcttgta ctgctcgtag
      541 tccttttcat agatacagaa ataaacttca ctttgtaatg aaccgatata gagggtgttt
      601 cccatacatt ccttttcctc tttgcgtacc agttcgccac tgcgatagct tttaaaactg
      661 cggaagacgg agatacattc ttcctgttgg cacttttcag tgagtacagg gatatttaaa
      721 atccctgtct tatcgttaat ggcaaggtca aggcgtttca tcacaccgcc agccaccaaa
      781 acgtccataa agaactcata ccagcttctt tgttgtgcca gaagatagct ttcaaattgt
      841 ctgcacccac gacctttcaa ttccaccaga actcctttgt ccagttcatg ggagcaaagg
      901 acgaatatgt cgcctaaagc ataatgctct gaataagaat agaaaccata gtcctcatga
      961 agaaaatagg acagtttcag ttgtaagatg ttttcgacca cctgctgtac gtctgttgtc
     1021 ggaaagcgaa ttcttacata atcaaacagc atttcaaggg gagcgtcggg attgaagcgt
     1081 tccagagctt cccaaaggga ctgctgtaaa tcctctgatg gcttgacttt tcctgtttca
     1141 atatcgctta gatactgcct tgtaatacca gtcgcaacag ctaaacggtt ttgagatagt
     1201 ccataagcca agcgtttttc ttttaaatgc tgtaaccaag tttgttcatt cagtaaaaat
     1261 ccctccaatc aaaaaggcgt atgtcaactt ttaaagccca tttgacatac gctgaaattt
     1321 tgtaaatccc ttgtaaccaa aggattttct aatgtttttt tgactgtttc ctgtcgattt
     1381 gtacccccct gttagatacc gaggggttaa gtgctggcgt ggctattgcc acaccagcca
     1441 gcaagatcag tccacacctg cgacttccgc ttcgcacgtc gcctgcgtgg actgtctgct
     1501 gttggataac tttttaattt cctccaagaa atcatatcct tttggtacaa ggggagtata
     1561 aaactctgat atgacacttg ttcctacatc aacatagcca cgacctttga ttcgctttaa
     1621 gaagaaatcc ttttgtacgt cactgccaaa catcatgcca tagcccattt cagacatacg
     1681 acctaaagcc actctgaaat taaactgatc acggattccg tcgcctaaat attttgcgtc
     1741 tggacgttga caagccagta ttagaaagaa gccagcttga cgacctaaca tgacaatctg
     1801 tttcagctta ttcataactg cggtgttttc ttttgttccc agcatttcca tgaaagcgac
     1861 gtattcatca aagattaaga agtgtgccgg gagacctaag taagcataat ttttgccagt
     1921 cttatagttc ttcatctgct tcatttcctc actacgtttc atcatttctt catagaatgt
     1981 ttcaatgcaa gaaagcaagt cttcttttct atagtagaca tttgccatca cagaacctaa
     2041 gtccgcaagg tcagcatttt tcgggtcaag aatatacagt tttgaatctg tatgaagcaa
     2101 ggcttcaatc agtgtcagta taaagtaagt tttaccgcca cctgtaccac cagcaatcaa
     2161 catatgaggg agcttatcat attcccacca tacgtttttc attaagcgaa gtttaccatc
     2221 tttagcttct acttcatcaa tagaaatacg actggctatg gtgtcataga gcaaagtata
     2281 ttccacatag gaatccttta actctttatc cgtcagctca cagtacaagc cactctctaa
     2341 tttcttttcc aagtgtaaga gttggtcttg atattttccc agcgtgattt ccacccgtat
     2401 ctgtatcaag ccatttttaa gtcgataata cattttaggg aagtaggtta tcttttcctt
     2461 tgtacgacca gcactatctt taaagaaacc ctctgttttg acctgttcag attcatacca
     2521 cttgttttca agtatcatct ttgccagttt ttgacggtgg taaagttgtt taaccgtatc
     2581 atagcgaacc cgtttgaata caaacgctac cagcaagcag ataagaattg cgacactgaa
     2641 actgataatt aaatagggaa tgtcaatctt atctgcttgt gataggttaa aatcctgcca
     2701 gttgatctgc tggattgtct tcacatgaaa cagtccgaca accagcagga aaacaggcag
     2761 gagtgacgct atcgtaaaat gaaagactaa atctttacca gatgggcgaa tccttttacc
     2821 acgctgtttc atgcgaaaaa gtctcctttc tacctagcga ctatttgtct tgtgtcggtt
     2881 ctttctttgc ttgtggttga gctttgaatg aactagaatc ctttgtcagc acaatatcgt
     2941 ctgccttgat ataccagtca acatctgctc cttgataggt ggcagtagca acggtgtccg
     3001 caatgggatt gataagttcc acccgtgcgt tataatcaaa ctctttcaaa ggcacgctgg
     3061 caggaatact tacttgaatc atgcgtcctt gtcctttgga ttttaagtca taggtacgtt
     3121 ccttgatttc atctgaaacc gacccgtctt cattttggat tctcacttca cgacgtagag
     3181 cagagaattt caattctcca aaagtcgtgt ctttatctaa tacaatgcca tttgctaatc
     3241 tcatcatttt tcctctcttt ctttattctt ttatcatgtc gtcagcatgt aaaaggtaat
     3301 ttgtaaaacc acgagtgccg attttgtagc cctctgcggt aatacgtgga ttgactaact
     3361 tcacacgttc ctcaaagccg aaatgttttt cgccagcttc agcaggaagc accaccacaa
     3421 tatcatctgc tctttgaaca tcagaataga gattatagct tcttgataag acagttagcc
     3481 gtccgttgat tcttcgctga acgactttat cctcgccagc aaattctaaa ttgccgaatg
     3541 ttttttccat gttgggaatc acaaatttaa gttccatatt tttacctatc ctttcttttt
     3601 tattggctga atgaatgttt gatggtctta aagagtgggg aacgaccttt tgattcttga
     3661 ttttttgttt tcataagttc acttcctttc aaaatcgggt aaaaaaatag acacctcatt
     3721 ttttgaagtg tctacctatt aaatattcaa attttattgg aagtatcttt atatcttcac
     3781 ttttcaagga taaatcgtcg tatcaaagct cattcataag tagtaaatta gtagtaaatt
     3841 gagtggtttt gaccttgata aagtgtgata agtccagttt ttatgcggat aactagattt
     3901 ttatgctatt tttctcttaa aaaatatcat tatttgtggt atggagcccc cgcgttgatc
     3961 cggaaggcac ggtagatttg ctcgacgagg atcaggcgca tcaattgatg tggatacgtc
     4021 attttgccaa aagagatctg agcattgctt cttttcatga cggcttcgct gagtcctaaa
     4081 gaaccgccga taacaaaaac aaggtggctt tttccttgga tacctaattg gtcgatttgt
     4141 ttagcaaaag attcgcttgt gggatttttc ccttcaattg ctaagccata gacgtattct
     4201 tgttctttga ttttcgctaa gatccgttct ccttcttttt cttttacttg tctcatttgc
     4261 gcttcgctta aattctccgg ggctttttcg tcaggaactt cgatcaattc gattttcgca
     4321 taggcattca gccgtttgac atactcattg ataccttgga tcaagtattt ttcttttaat
     4381 tttcctactg aaataatttt gatattcatg ttttctctcc tttgatcttc acgctcactt
     4441 tgtttattat aatcaatttt ttcgtctata tgtttatttt gactattttt gttaaaaaga
     4501 tttccccaac agttatgcac aacatccaca ggtttatcca cagaaaacag cgttgtttta
     4561 ccttatttca tcacattcat taggcaaaca tacgttttat aagaatttat ccactttata
     4621 cacaggctgt ggatatgttt tatcccttat ttttccaatc ctatccgcgt agttttacac
     4681 aatatctgtg gaaaaagaaa atcaaatatt ttcatctgaa aacaatgatt tttcctaaag
     4741 tttttcataa aaagttcaaa gtctcaaagt agactaaagt caacaaataa gactatacta
     4801 acagtagata aatgaatgta attggaggag gaacacatgg atagaaaaaa tgtgacacca
     4861 aagatgaaaa aaaataaaaa taatagcctc tggcgtaagt tgggtctggg gcttgttgga
     4921 gggatcgttg gaggactact gacagctggc attttttatg cagcgatggg cactggcaac
     4981 aatagttcta ctgctacaag cggcaatcaa aattctgccg gtgaaacagt tgtggaaaat
     5041 gtcaaagtca atgtagattc tgatatcacc aaagcggtag ataaagttca agacgctgtc
     5101 gtttctgtta tcaacttaca aagtcaaaac caatcaagcg gttttggcgg attattcggg
     5161 cagcaagaag aaagtagcag ctcagatgat agtaatttgg aagcttatag tgaaggaagc
     5221 ggcgtaatct acaaaaaaga cgggaatact gcttatgtag tcacaaacaa tcacgtagta
     5281 gatggacagc aaggtttgga agtcatgatg aaagacggta cgaaggtaaa agctgaatta
     5341 gttggaacag atgcctattc agatttagcg gtgttgaaga tcaattcaga caaagtcgaa
     5401 acggttgcct cttttgggga ctcaagtgct ttgaaggttg gtgaacctgc gattgcgatt
     5461 ggttccccat taggatctga atatgcgaat tctgtcactt caggaatcat ttcttccttg
     5521 aaccgacaag taacaagtac gaatgaatcg aacgaaacag tcaatatcaa tgcgatccaa
     5581 acagatgcag cgatcaaccc gggaaattct ggtggtcctt tagtgaatat cgaaggacaa
     5641 gttatcggta tcaactcaag taagatcgca agtacttctg aatcgacttc taatgtaagc
     5701 gtagaaggaa tgggatttgc catcccaagt aacgatgtag tgaatatcat caaccaactg
     5761 gaaaaagacg gaaaagtgac acgtccagct ctaggtatca caatggtcga cttatctgcc
     5821 gtttctactc agcaacaaga acaaatcttg aagattcctt catctgtaac taacggtgtc
     5881 atcgtgacaa atgtccaaac agctacaccg gcagaaaaag ctgggttgaa acaatacgac
     5941 gtcattacta agatcgatga caaagaagtt tcttctggtg tagaacttca atctgctttg
     6001 tataagaaaa aagtgggaga ttctgtcaaa atcacttact atgaaggctc gaaagaaaaa
     6061 acaactactg ttgaattgac gatcgatcaa tcggcattaa aacaaaatca aaatagtgaa
     6121 aattaataaa a
//
LOCUS       DAFEEZ010000107         6037 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000107
VERSION     DAFEEZ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6037
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.113"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..334)
                     /locus_tag="LP245_002739"
     CDS             complement(<1..334)
                     /locus_tag="LP245_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1520594.1"
                     /translation="MHVRCGAGENLEITSKGYLSLFTSDFLAGLGFGATQMLGELEGI
                     YFGYNVDTGRNVYLKPALASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFG
                     GQAVIVDPK"
     gene            complement(374..2140)
                     /gene="ltrA"
                     /locus_tag="LP245_002740"
     CDS             complement(374..2140)
                     /gene="ltrA"
                     /locus_tag="LP245_002740"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL1520595.1"
                     /translation="MQETFDWLYERSSKQATKGIDLYKIIMSEENILLAYRIIKSNTG
                     SKTSGIDNQTISDFKFQNKQKFVNDIRKTIENYQPQPVRRVNIPKSNGKTRPLGIPTM
                     KDRLIQQMFKQVLEPICEAKFFKHSYGFRPNRSTEHAIARCNFIAHKCKCHHVVDVDI
                     KGFFDNVHHGKLIKQLYTIGIKDRRVLAIISKMLKVTVAGQGTSTSGVPQGGVLSTLL
                     SNVVLNDLDWWIANQWETFQTKRKYSSVDNMHHALVKSKLKKMHIVRYCDDFKIFTTN
                     HKHAVKIYHAVKGYIKQRLNLDISPDKSKITNLRRNYSEFLGFELKVIKQKKQQYVTV
                     SRVSKKSKSRIKKEIREKIKAIQKSPTRKTVNQYNQYVRGIQNYYQKATLINHDFSSI
                     YYSCLPALYNRLKPFGKYEIPRSPPITYKKFYPLTKRTFCVRKNYLFPLDSVKWKRLE
                     FFKPHINNYTQDGRLAKLRKLKPSVYSELVTLSTMETDESLEYLDNRLSRYSMQNGKC
                     SVTGIFLRTQDVHCHHIIPRKFGGTDEFDNLVIIHKWVHRLIHAKTKETIKEYLQLLQ
                     LTNKQMKKLNKYRLECNLTEFH"
     gene            complement(2884..4113)
                     /locus_tag="LP245_002741"
                     /pseudo
     CDS             complement(2884..4113)
                     /locus_tag="LP245_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP/GTP-binding protein"
     gene            complement(4100..4489)
                     /locus_tag="LP245_002742"
     CDS             complement(4100..4489)
                     /locus_tag="LP245_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1520596.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHMPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(4572..5297)
                     /locus_tag="LP245_002743"
     CDS             complement(4572..5297)
                     /locus_tag="LP245_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520597.1"
                     /translation="MLEVMIIMNFDFDLKSFIDIFVPVLTSFAVCFITLFFTNKQHKK
                     AMKQQERQHEESLDLSKQQYADEKQRNEEQDRLSYYPYLKLIPKISEHRFAGKMVKSD
                     ENDVFKLPFELINEGLGMAFSIDFVYLEETINTNDHEVNLLSLLSAQKHIDDSLDALG
                     VSAPIDTDILRVGKKTEFELYWMKYNNEVMSIPKYSVSKWEIKIRFSDFQDRIYQQRY
                     TFITSAGYQEIHRLWSDKPQLID"
     gene            complement(5346..5849)
                     /locus_tag="LP245_002744"
     CDS             complement(5346..5849)
                     /locus_tag="LP245_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL1520598.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFSPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPIGEVALEIQHAFFNSFEEMVEH
                     VDDIICYPDCNDMSDVAYYLIEETGAFGEVPTHLQNYIDYEAYGRDLELEGNYLVTNR
                     GTFEFIG"
     gene            complement(5861..>6037)
                     /locus_tag="LP245_002745"
     CDS             complement(5861..>6037)
                     /locus_tag="LP245_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520599.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
BASE COUNT         1767 a         1208 c          965 g         2097 t
ORIGIN      
        1 ctttgggatc aacaatcacc gcttgaccgc caaacaggac agcatagtaa actaaaagat
       61 tattactaaa ggatttccca ccaccaagtg aaccaagaaa agcggcggcc agtgcattgg
      121 tgacggaacc tttgacccct tgtgaagcca atgccggttt aagataaaca ttgcgtccag
      181 tatccacatt gtagccaaaa taaattccct ccaattctcc taacatttgg gttgccccaa
      241 agccaagccc agcaagaaaa tcagaagtaa atagcgatag gtaacccttt gaagttatct
      301 ctaggttttc ccccgctcca caccgtacgt gcaactttca tcgcatacgg cgttccaact
      361 tgttcgtatt tctttagtga aattcagtta aattacattc taaacgatat ttgtttaact
      421 tcttcatttg cttatttgtt agttgaagaa gttgtagata ctctttaatc gtttcttttg
      481 ttttggcatg gatgagtctg tgtacccatt tatggataat aactaggtta tcaaactcat
      541 ctgtaccccc aaatttacga ggaataatat gatgacaatg aacatcttgc gttcttagaa
      601 aaatccctgt aacggaacat tttccatttt gcatagaata tcttgacagt cgattgtcta
      661 agtattcaag actttcatct gtttccatcg tactaagggt aaccaattca gaataaaccg
      721 aaggttttaa tttcctcagt ttagccaatc gtccatcttg cgtatagttg ttgatgtgag
      781 gtttgaaaaa ttctaacctt ttccatttca cgctatctaa tggaaataaa taattcttcc
      841 taacacaaaa cgttcttttt gtgagaggat aaaacttttt atacgtaatg ggtgggcttc
      901 tagggatttc atattttccg aatggtttta aacgattata tagtgctggt aagcaggaat
      961 agtagataga agaaaagtca tggttaatca aggtggcttt ttgataataa ttctgaatac
     1021 ctcgtacata ctggttgtat tggttaacag tttttctagt aggagatttc tgaattgctt
     1081 ttatcttttc tctgatttcc ttcttaattc tactttttga tttctttgag actctcgaaa
     1141 cagtaacata ttgttgtttc ttttgtttta tgacctttag ctcgaatcct agaaattctg
     1201 aataatttct tctaagattt gtaatttttg atttgtctgg tgaaatatct aggttcaacc
     1261 gttgtttaat atatcccttg accgcatgat agatttttac tgcatgttta tgatttgttg
     1321 taaagatttt aaaatcatca caataacgta cgatgtgcat tttctttaat ttcgacttta
     1381 ccaaagcatg gtgcatatta tctacactgc tatattttct ttttgtttga aatgtttccc
     1441 attgattggc aatccaccaa tctaagtcat ttagaacaac attcgataat aatgtagata
     1501 acacgccacc ttgtgggacg ccagaagtgg aagtgccttg tcctgctact gtcactttta
     1561 acattttaga gattattgct aatacgcgtc gatcttttat accgatggta taaagctgtt
     1621 tgattaactt tccatgatgg acgttatcaa agaatccctt aatgtcgaca tctaccacat
     1681 gatgacattt gcatttatgt gcaataaaat tacatcttgc tattgcatgt tctgtagagc
     1741 gattaggtcg gaacccatag gaatgtttga aaaattttgc ttcacatatg ggttctaaca
     1801 cttgtttaaa catttgttgt atcaagcggt ctttcatagt gggaatgcct agaggacgag
     1861 ttttcccatt actttttgga atgttgactc gtctaactgg ctgcggctga taattttcaa
     1921 ttgtttttcg aatatcattt acaaactttt gtttgttttg aaatttgaaa tcactgattg
     1981 tttgattatc tatcccagat gttttagaac cagtatttga tttaataatt ctatatgcta
     2041 gtaggatatt ttcctctgac ataattattt tataaaggtc aatacctttt gttgcttgtt
     2101 tgctacttct ttcatagagc caatcaaaag tttcttgcat ttgatagtat tcataatatc
     2161 gtaattctgt actcactgat ggattatttc tcctaacttt aaaattagtc ccatcctctt
     2221 accagatctt gtgagtttca tttaactgta ttcacttttc aaagaacaag tcttggggct
     2281 atccctccac gttgattaga cgcttcacag gtactgtgcc cctactctcg cagaaattaa
     2341 ggattttcga ctattagtct tatatccaac gctccaataa cagttgttga ataagtgttt
     2401 tctgttttcc tcgttccagt tattctagcc atacatctat ccttaggtgc ttactttgag
     2461 cctgaatatt atataaggtc attgttcctt atcccgaatt tcataaatac gactcttact
     2521 tttcggtaat attcgttgct tttgcaaccc aattatcttt cgataaaagt catcctttag
     2581 acccgtacat tcgcaagttc gtcagttccg taggaacatt ctcaccatag atagtttgtg
     2641 gcgtcccggc atatccttta ccatataagt tattacttac ttaggtattg ttctgccgac
     2701 tttacctagc ttcacacgaa tattcactgt tatgaatatt cgcatgtagg agtatcagac
     2761 cagttgcttc aaccaacttg acggttttca tttcaactgt gaaataacta gttgtaatta
     2821 tctttagttc ttgataattc tcccatttca tgcctatgca cttataggga aacgagtcgc
     2881 accatattgg atatagtcat tcatgtatcg cttgctagct ggcaaaaact cttcatgaag
     2941 tcccatcata tcgccaaagg gacgaaccaa ttttacattg gtatcatcat aaaaatctaa
     3001 aacctcatca caccgacgtt ttaattcatc caatgattct gcactcactc gaacaacata
     3061 gcttaatttg tacatggatt ctttggattg atccaacgtt gtttctagtt catccacgga
     3121 gtccaacgca tccaagacat tggaattggt ttcattgtcg gactggtacg catggttgtc
     3181 taagtctttc agttcttttt tcttattgcg aactgtcgcc agtgcctttt tattcgtcac
     3241 gatttctaca ttcatactcg tgtcgattgg gaaagtgaat tgttgttgct ggtaataaaa
     3301 gagttcagaa gatggaaact ccatctcacc gacaatcgta ttaatcgtta gataggccac
     3361 ataagattca tgattttcat gttccatgtg taagtaccga ggcttctctt caatcaaaca
     3421 gcgacttggg cgaagtaggt catagcgctt tatcaatgtt tcagatttta gctttttctt
     3481 agacaactga aattcatatt cttcaaatgg tgttcctttt tctccataaa tgtgttcaat
     3541 caaataagtt agatcactag gtgttactcg tcttactttg aatctacgag ccaatttact
     3601 ttccatcaat ttttcaagct tagtataccg gcgaatttct tcattggata acgaaacaaa
     3661 atcacccatc aaatgatgat tcactccata gacaaactct tgaagtccgg ataaaaaaga
     3721 gttcttgaga cttttcaggt ttacttcttc gtctgtgaca atcagtttga agccaataaa
     3781 aaagcgatag tcaatttgac tatcgccaat catcgatacc aatgcatccg tctgtaagtc
     3841 gattctctgt tttgcgactt ctttcaaacg accagttatc tcttttttcg accgttcctg
     3901 cgtggcacga atgctgcttt ctgtcgcaat ttgtaacgca tgaatcttac cttcacgatt
     3961 ttgcgcaatc aattggcgaa agttatcgtg gacttgatac ttctgttcaa gtgataagaa
     4021 ggagtaattg taagggacta gttcgtagta agcaaagcac tctccctctt ggttaaaaac
     4081 aagattattt tcaatatatt taatcgggta cataattcac actcctcact agggtgattg
     4141 gttcatccca tcgttttttc tgttctttga ctttctttcc tgcaaaagta accttaaatc
     4201 gcaagtgata actaataaag gatcgtaaaa accctaatgg cttctttcca tcaaaggtct
     4261 tttgcgacat aaaccaagtg actgccacag gtatgcccaa gtattttaaa aatgccccct
     4321 ctatcataga tagtggaggc atatgagcaa acacaatgac aaacagcaag gataagacaa
     4381 accaagccat ttgattaaag gttacaggaa aaggcagctg aaagtcattg attgcgtaaa
     4441 tgactttttc aactgcccag atactggtat agctttttat ttttttcatt agtttcactt
     4501 cctaaaaaag cgcctgataa agacgactct gcatgaatat taattttctt tttaaaagtg
     4561 tattccaact ttcaatctat caactgaggt ttatcagacc ataatctgtg gatttcttgg
     4621 tatccagctg aagtaataaa agtatatctt tgttgatata ttctatcttg aaaatcacta
     4681 aaccgtattt ttatttccca tttactcact gaatatttag ggatactcat tacttcgtta
     4741 ttatatttca tccaatataa ttcaaattct gtttttttcc ctactcttag aatatctgta
     4801 tcaataggcg ctgaaactcc taacgcatcc agactatcat caatatgttt ttgagccgaa
     4861 agtaatgata atagatttac ttcatggtcg tttgtgttga tagtttcttc taaatacaca
     4921 aagtcaattg aaaaagccat tcccagacct tcattaataa gctcaaatgg taatttaaaa
     4981 acatcatttt cgtcagactt taccatttta ccagcaaaac ggtgttcaga tattttgggt
     5041 ataagtttta aataagggta ataacttaga cggtcctgct cttcatttct ttgtttttca
     5101 tcagcatatt gttgctttga taaatcaagt gattcctcat gttgtctctc ttgctgtttc
     5161 atcgcttttt tatgttgttt atttgtaaaa aaaagtgtga taaaacatac tgcaaatgaa
     5221 gttagtacag ggacaaatat gtctataaat gatttaaggt caaagtcaaa attcataata
     5281 atcataacct ccagcattat atatttatca ataattatat ccctaaacct atatcatgaa
     5341 aatgtttatc ctatgaattc aaatgttcct ctatttgtca caagataatt tccttctagt
     5401 tccaagtcac gtccatatgc ttcatagtca atatagtttt gcaagtgtgt aggcacctct
     5461 ccaaaagcac ctgtttcttc aatcaaataa tacgccacat cactcatatc gttacaatcg
     5521 ggataacaga taatatcatc cacatgctcc accatttcct caaaagagtt gaagaaagca
     5581 tgttggattt ccaaagcaac ttcaccaatc ggtgttcctt ctagttcctc tgctaaacca
     5641 cacaaccgat tgatttcctc aattggtgta tattcatcaa tctcaaaagg caactcataa
     5701 tcatggatcg catactcttc gtattcgtca tttaaaccaa tccgttcttt cacttcgtca
     5761 aaatcgacag gtgggctaaa ccaagccccc accaattcac cttcgttata ttttccaagg
     5821 ttcgcaatat atacacgcat ctgctccata atggtccccc ttacgcaccg acaatccgat
     5881 taaacaagtt gagtaagaca tctttcacac cagaagcgtt gaagaccagt cctaccgcaa
     5941 tcagcgcaat caccaaaaaa ccaatcagct tggaaaactc acgtttgaag cctaaaaata
     6001 aaccaatgac cacaattgcc aataagacta aagattg
//
LOCUS       DAFEEZ010000108         6029 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000108
VERSION     DAFEEZ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6029
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.114"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(439..602)
                     /locus_tag="LP245_002746"
                     /pseudo
     CDS             complement(439..602)
                     /locus_tag="LP245_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390190.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
     gene            complement(955..1644)
                     /locus_tag="LP245_002747"
     CDS             complement(955..1644)
                     /locus_tag="LP245_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBL1520600.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFSHTRVGKNGKTFKMHKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYIGHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            complement(1707..2471)
                     /locus_tag="LP245_002748"
     CDS             complement(1707..2471)
                     /locus_tag="LP245_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBL1520601.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQITAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIVKDFG
                     KEKVVQMKQVAKDLINGDEISYPIYEEVKKKKFGLF"
     gene            complement(2499..3197)
                     /locus_tag="LP245_002749"
     CDS             complement(2499..3197)
                     /locus_tag="LP245_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBL1520602.1"
                     /translation="MARTQKQKAAQTHVVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTIAANIAVVFAKSGQRVLLVDADLRKPVVYETFQLNNAS
                     GLSTALSSSGSVADEIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYRN"
     gene            complement(3209..3988)
                     /locus_tag="LP245_002750"
     CDS             complement(3209..3988)
                     /locus_tag="LP245_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBL1520603.1"
                     /translation="MEETISLKEIFGTLRKHLATIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSENSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGSAPARPKATNDKTAPSRRSRSRV"
     gene            complement(4004..4948)
                     /locus_tag="LP245_002751"
     CDS             complement(4004..4948)
                     /locus_tag="LP245_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL1520604.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(4994..5773)
                     /locus_tag="LP245_002752"
     CDS             complement(4994..5773)
                     /locus_tag="LP245_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520605.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKERVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISVAYATKAQTVAQQMGYSNINY"
BASE COUNT         1643 a         1230 c          988 g         2168 t
ORIGIN      
        1 atatcttaat tatctatcca tttcatccta cgcattcttg cgtaaataca attcactctg
       61 ttgagctgat ataaatcatt ggtggtacaa agataaaatg ataactgttt ctatacctcc
      121 aaaaattcca gtaaatatat ctatagatag tttcaaaaaa aattgtctta gtttcataat
      181 atttaagata gtggtacata ctttataaca acgtactttt ccaaatatta ttttccgtta
      241 tgaacatcca atatattaca aagtttaaaa gtttagatga actataatct tcatttctgc
      301 acagtggata ataaattctt atagataaaa aatagcctct tctaaagtca caaatacctt
      361 actcccacat tttaagtaaa cactctgcag cattctcttt gttataaaat gatagatatt
      421 cctcaatttt atctcttatt atgttattat cagttgatac cattccatta atgtttcaga
      481 ataattacaa tattttggga ccggataact cccttttgct cgtaaccact catatccgtt
      541 aggattcact aaaagtttac cgtttatttt tcgattcttt ttttgaaccg tcccatgaac
      601 ataccgattc aacaagctaa attataaaaa ttggtgtgct gtcattattt tttggaaaat
      661 ttattaatgg ctatcaatat acttttgtat catactaaat agctcgtcag ttcctatatc
      721 ggatatacca atattaaagc atttagatca ttatatttaa gagtggtatc atcccaaaat
      781 ttcgaatatt ttcttttata taagaataat gatactgaat tgccccattc acctttcttt
      841 ttttagattt tctacaagtg attcaaaccc tccataatta cagttattac ttttgaaacg
      901 ataatatgaa catgtgtaat cttttttatt aacaatccat cattctatcc ctaactaata
      961 tgctccattg ggcttgacaa taacataaaa cgtttttaaa atcaacctca agtcgtacat
     1021 taaacttcga tgaccgatat actctaaatc caactcaacc attttatgga aactaacatt
     1081 atttctatca ctaacttgcc acaaacctga acaaccaggt tttacataca agcgttgaag
     1141 atcatatctc gtgtactcag ctacttccct ctccaaaggt ggccgtggac caattagact
     1201 catatcgcct tttaaaacat tccatagctg tggcaattca tcaatgcttt tggcacggat
     1261 aattttacct attttagtga cacgcggatc ttctttcatc ttgaacattg caccttctat
     1321 ttcattttga tcaagtaatt cttccaattt ttcttcagca tctaaacaca tcgaacggaa
     1381 tttatgcatt ttgaatgttt ttccattttt accaacacgt gtatggctaa aaaatattgg
     1441 acttcctggc tcttcttttc tgattcgata agctacatag aacatcaaag gagaagctaa
     1501 aatcaaacca ataatgcttc ctacaatatc aatcattctt ttaaaaaata aatagatata
     1561 tcgtttttca actttttctt tatccaacca aacttgatta ggatgtactt cactaatacg
     1621 agataataaa tcttcacttt ccatactttc agtccctttc actatcttca ctctctcctc
     1681 atttgttttt atctacgaat aaagaactaa aataaaccaa acttcttctt ttttacctct
     1741 tcatagattg gataactgat ctcatccccg ttgatcagat cctttgcgac ttgtttcatc
     1801 tgtactactt tttccttacc aaagtccttg acaatctgct catagcactc ttttaagtaa
     1861 aaggtgcgct tagagacccc gtgtgcatca gaagcagcca tctgcacgag attatgtttg
     1921 accattgttt tggctgtttt ctggatgtct ttgccaaata caccaacata acttggcgca
     1981 gtaatttggg ccaaacatcc catatctagg aacggaagca aatgatttgg gtcttctcga
     2041 aaatgcgcgt tgcgttctgg atggacgatc actggtgtct ttcctagttc taacaactca
     2101 aaaaaaagcc attctgcata taacggcact tccagtgtcg gaaattcgat cagaagatat
     2161 gtatcatcta aatctgtaaa taaaatttca tctcggtgga tgtcttcgat gagcgttccg
     2221 gtaatacgta cttcttgtcc ttccaataac gtcaaaggca actgtctttt ctctaattcg
     2281 gcttgtaacg aagcgactag agaaatgact tgtgattttt cattgctgta ttttccatta
     2341 ttgtggtgtg gtgtgcataa aatatgcgtg atgccttgct gaatcgcttt ttcagccatt
     2401 gcaatacttg cttctaagtt ttctgccccg tcatcgattc ctggtaggat atggcaatgt
     2461 agatcgatca tttctcttgt ctcctctctt cttattcctt aatttctgta gtaataacca
     2521 gcatctttgc tatgttctgc tccgttgtat acaacaccta agactcgtgc ttgtaccatc
     2581 tctagcagtt cttttgcttt agtcaaggat tctttacgtg atgtattttc acgtacgacc
     2641 aataaagtgc catccgtttt tgaagacatg atctgtgcat ctgttacggc tactactggt
     2701 ggcatgtcga agatcactac atcaaatagt tgtcttgctt ctgctaaaat ctgatccatt
     2761 cttggcgagc ttaataactc tgatggattt ggtggtttag gtccacttgg cagaatcgac
     2821 aaattctcga ctggtgttcg ttggatctca tctgctacac ttcctgatga actaagtgct
     2881 gtacttaatc cactggcatt gttcagctgg aatgtctcat agacgacggg tttacgtaaa
     2941 tctgcatcga ctagtagaac tcgttgaccg gatttagcaa aaacgactgc aatgtttgct
     3001 gcaatggtgg attttccttc tccaggacct gatgaagtca cgacaatcgt tttgatttgc
     3061 tgaccagctg cggaggcaaa ctggatattc gtccggatcg tacgatattg ttcggcgatt
     3121 ggtgaagatg ggtttgttaa tgtgatcaaa ctgactacat gagtttgtgc tgctttttgt
     3181 ttctgtgttc gtgccatttt tcttcctcct agactcttga gcggcttctg cgtgatggag
     3241 ctgttttatc gtttgtagct tttggtcgtg caggagctga tcctttttta cggataccag
     3301 cgttcaattc tttcgctgac atttctggaa ctgttcctaa gattgggaat cctaatgtat
     3361 ccgtcacata tttttcatct ttcactgtcc gatcaagtaa ttcgaataag aatgccaaac
     3421 ctacgcctac catcattcct aatactaagc caatcactag attcaattta ttatttggcg
     3481 aaacaggtgt cgtattggca actgcacctg agatgatcga gattttatcg acattcatca
     3541 cgtcttttgc gttctcttgg aaaacttgtg aagttgtatt agcgatctgt tgagcagtca
     3601 ctgcattcgt gcttattgcc tggatcgaga acatttgtga gttttctgac tgattgacgg
     3661 agatcgcatc tttgatttgt ccagcggtca ttttcacatt gtcttctgtt tctagacgat
     3721 ctttgacttc atttaatact agatcactaa cgatcatatc tttatacgta ttgatcattt
     3781 gcaggttcgt attgacatca ttgacattcg ctgtgtctga ttgcggcagt gtcacgatca
     3841 attgtgcttg tgaactgtat tttggtgtca agatgaaaaa tgttacgatt cctgagatgg
     3901 ccaagccagc aaacattgag atgatgattg ttgccaagtg tttgcgtaat gttccaaaaa
     3961 tttctttcaa gctgattgtc tcttccattt tttctccact ttcctattta ttctctagat
     4021 tcatttgatc ttttaattct tttttcacac gatcaagttc ttgatcgctg actttttgat
     4081 aggagatatt atcttgcatg aagccttctc cttgcagctg atcttgcttg atcgtaccaa
     4141 atgcctcccg ataatctaaa gcgatttttt tcatttcatc aaagctcatg tctgttttca
     4201 tattcgattc tagagcattc aaaacggatt gatagttgct gacaccgttt agactcaata
     4261 cttttttcgc tacaccttct acgatctttc tttgacgctc ttgtctacca tagtcaccat
     4321 ttggatcttc ataacgcata cgagaataag ataatgcctg atccccgttc aatgtgattt
     4381 taccgattgt aaagtcatag ccatcttgtg agaaagtgag gtcattattg acttcgatac
     4441 caccaactgc atcaacaagt tcttttagcc ctttcatatt gatagagaca tagtgatcga
     4501 ttgggatgtc tacatatttt tgtacggtat ccatcgccat ggcagctccg ccgaatgcgt
     4561 aagcgtggtt gatcttgtct tttgtgtcac gacctacgat gtcgacatac gtatctcgag
     4621 gaatgctgac gatcgttgtc tgtttgtctt caggactgac tgtggcaacc atcatcgtat
     4681 ctgatcttcc ttgatcgacc cgacctaaat ctccagtatc aatccccatc aatagaacag
     4741 agaaagattc ttgtttgtcc agatcaactg gtttcgttcg ttctccttgg gttcgttcca
     4801 ctgattcgta agttttctca atagaatgtg agagatccag atataatttt gctcctactc
     4861 ctacaattgc taatactaat acgataagaa ctgctaaaat aatcagaaat atttttttcc
     4921 ctcttgattt tcttcttcgt cttgccatag tttcctccgt ttgctaacct tgcttgaatc
     4981 atcgctttaa ctgtcaatag tttatattgc tatagcccat ttgctgagca acagtttgtg
     5041 cttttgttgc gtatgctacg cttatttttt cattccggat ctgctctatt tgactgagcg
     5101 ccgtcaaata ttgatcgtaa gtagcggtgg cagtcacttg accatccttt aacatcgtat
     5161 cgaataactg atctagttgc gtgacttgcg cgatctgggt atcagcgaat cctagatatt
     5221 gcataacaac cgttttccaa ggactatctt taaaaaagct catattttca cgtacacgag
     5281 cgacatctgc acttgtcacc ctttctttga tgatgacatc gtctacagct tgctgccagt
     5341 ttgatacatt tttagtaaat aaatcgttga cagctgtctg gatcttcagt tttgattctg
     5401 cactatctaa ctgtgtcacg attgctttct tctcatcttg gattgcaaca gcttctttag
     5461 gcaattctga ttctttgatg tcgtaatcat ctgctgaaag tttgacagag gatagcttat
     5521 ttgacaaact tgtgattgtt tcttctgtta tttcagggtt tagaaaaatt ttttcttttg
     5581 tactatacag cttgtctact tcttttgata aagaagtcaa ggtgtctttt tgattggtga
     5641 tggcagattc tgcataattg atccgttgct gatgttgccg ctgattattg atatggtatc
     5701 caaacaaaca gatcgcaata gcacctgcac ctaccgccac agcagtcaat gacttgacga
     5761 atggcttttc catagattcg ctcctaagta ttgatgatag ataaattaag atataattca
     5821 cttacataaa aatgacagtt ttttatttaa aaaaacataa ttaaactaat atattcacag
     5881 aaatatttgt aaacaagttt tccctatata atcataccac aaactgcttt cttgactagg
     5941 gaaatttacg atttaaaagt aaataaaaca ttaataagat aacaattaat cgattttact
     6001 tttatttcct taattttcat aggtgtttt
//
LOCUS       DAFEEZ010000109         5876 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000109
VERSION     DAFEEZ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.115"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            640..1374
                     /locus_tag="LP245_002753"
     CDS             640..1374
                     /locus_tag="LP245_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL1520606.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1390..2559
                     /locus_tag="LP245_002754"
     CDS             1390..2559
                     /locus_tag="LP245_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL1520607.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2575..3570
                     /gene="lacD"
                     /locus_tag="LP245_002755"
     CDS             2575..3570
                     /gene="lacD"
                     /locus_tag="LP245_002755"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBL1520608.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYAEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3649..4575
                     /locus_tag="LP245_002756"
     CDS             3649..4575
                     /locus_tag="LP245_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBL1520609.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4594..5844
                     /locus_tag="LP245_002757"
     CDS             4594..5844
                     /locus_tag="LP245_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL1520610.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1967 a          956 c         1202 g         1751 t
ORIGIN      
        1 tttgaaaaat gctatttcga ggtagaagga tattatataa gcacggttga ctaaacgaag
       61 tgataataaa aaaagttatt caagaataag aaaaattatg atacgaattc agataaactg
      121 gagaatacag agacctttaa aagggataag aaacaacata aattcctctt aagagagaac
      181 gaaaggacaa agccagcaac ttgatacacg agctagtatt agaggaattt attctcatag
      241 actccctttt gaatacgttt caactttaat tttcatgttc ataaatgatt tgaaaccaaa
      301 gcaaatgcgt tgcacttttc ctccgtcttc cgaaaatcgt tcaattcact ggtaagtagt
      361 catttgatag tttgaggcaa attgttgatt gatgaagggt aggagctaaa aaaagatacc
      421 agttgaagag agaaaaagaa aaaaatagag ggtgttcttg aatgaaaaaa gttggaaaat
      481 tatttttcat ttccttttat tcctattaaa gtcagtgatg tcaatcatat taacaagact
      541 aaaaatgaaa ataaaaaaaa gattgttctt agtattgact cataaaaaat accactacta
      601 tacttacatt gtggttatag ccagttagga gagacatcga tgcaaaatac ctttcaatca
      661 aaatcacttt attatcagct ggtagaaata ttgaaacaac gaatcgaaaa cagtatggtc
      721 gctcatgaca agctgccatc agaaagagag ttgaccagtt tttatggcgt tagtcgcacg
      781 acggtgcgac tagcattgca agaactggaa aaaatgggct acatttatcg acaacatgga
      841 aaaggaacct ttgtttcgga attaaggaca aatgcgactg atctagctgg cgcatatagt
      901 tttaccgaac aaatgcgggc aatgggcaaa catcctgaaa ccaagatatt ggccttcaag
      961 aagattgaag caactaaata tttagcgagt catctgaatg ttcaactagg tgagccttta
     1021 tttcaattag accgattgcg cttagctgat gatttgccaa tgatgatcga gaaatcctat
     1081 ttgccagtga agctatttat gtccctttct caagaaattc tatttctgaa acctttatat
     1141 aatttgtttt cagagaattt caatcaaatc gtacggttgg ctgacgagga attttatgcc
     1201 agcattgtcc agaaagaaga tagtgagttg ctaaatattc cagaaggatc accagtgctc
     1261 catttagttc gctcaaccta taatctcgag aacgaagtga ttgaatttac attaagtgta
     1321 gcgcgggctg ataaatttca ttataagatc aggcatctgc gttccactaa ctgaattgga
     1381 ggaaagaaaa tgtttatgtt ctcaaaagaa gaactacgaa agctaggagc agaaaatact
     1441 acccgagaaa ttcgacaaca accggaactg tggcatgaga cgtttgaccg ttatcaagaa
     1501 acagttgcag atttagatcg tttgtttacg gatgcgaaac aacatgctgg agagcgacca
     1561 atccgagtca tttttacagg ggccggaacc tcgcaatatg tgggagatac actaattccg
     1621 tttcttacta gtcaaggaaa tacgaaccag tttatttttc aaagtattgg ttcgaccgat
     1681 atcgttgcta cgccaaaaga atacctgatt cctgatgaga caacgatctt ggtctcattt
     1741 gcccgtagtg gaaatagtcc agaaagtcta gccgcagtta agatggccaa tcagctggtc
     1801 aacaagatct atcatatcgt gatcacctgt gcaccagacg gattattggc tacacaaatg
     1861 cctacaaaaa aagaaaatct agttttacta atgccaaaca aagccaatga cgctggtttt
     1921 gctatgacaa gcagtttcag ctgtatgacg ctgactgcgc tacttatttt tgatcaagca
     1981 agcaatcagc aaaaagaaag atatgttcat caattaagcc gactaggaga agaagtcatc
     2041 caacgagaat cagagatcca agggtatctg gcatcagact ttcatcgcat catttactta
     2101 ggttcgggaa gcttaggcgg attgactaga gaagcgcaat taaaagttct cgagttaact
     2161 gctggaaaaa tcgcaaccgt atttgataca tctttaggat tcagacatgg tcccaaatct
     2221 tttgtcaatg agcaaacatt ggttttcctg tttgtcagca atgactcata tacgcagaaa
     2281 tacgatgtag acatgctgga agaaatcaaa aatgacggta ttgcccaacg cgttgttgga
     2341 attggtcaaa agggttcatt gtttagtggt gattcctttg aattagttgc agattcgtta
     2401 ctgccggatg gctatcttgc tttagcagat atcatggtag cccaaacgat cgcattactt
     2461 tgttcggtga aggttggtaa tacaccagat acaccatcgc caagtggaac agtcaatcgt
     2521 gtggtcaaag gcgtaacgat ttatccatat gaaaaatagg aaagagtgtg aagcatgtta
     2581 gaatggtcgg aaaataaaag acaagcaatg gaacgtctat cgacgccaga aggcattatt
     2641 accgctttgg cgatcgatca gcgaggcgcg ctgaagaaaa tgatgtcggc tttagggatg
     2701 gaagcgacaa aggaaaaaat tgagcagttt aaaacactaa tttcccaaga attgactcct
     2761 tatgcctcag caattttatt ggatcctgaa tacggactgc ctgctgcaca gaagcgtgca
     2821 gcagcgagcg gtctgctgtt ggcatatgaa aaaactggtt atgatcaaac cgtacccggc
     2881 cgcttgccgg atctgctgtc ggactgttca gttctgcgat tgaaagagtt aggtgcggat
     2941 gcggtgaaat ttttactgta ttacgattat gcagaagcag aggaaatcaa tcggcaaaag
     3001 caagtttttg ttgaacgaat tggaagcgaa tgcatggctg aaggactgcc attttattta
     3061 gagttattgt catatgatgc taaaaatgta gatacgaaat cgctttccta tgccaaagca
     3121 aaaccgcgca aagtgatcga aatgatgaaa gaattctcga aaacccagta taaagtagat
     3181 gtcttaaagg ttgaagtacc agtaaacatg tcatttgttg aaggaaatgc aacaggggag
     3241 atcgcctata cacgtcaaga agctgccgct tattttaaag aacaaagcga tgcaacagat
     3301 ttgccgtata tcttcttaag tgctggggta tcagcggcat tattcatgga gacattgcgt
     3361 tttgccaaac atgctggggc acgattcaac ggtgtactct gtggcagagc aacttggaaa
     3421 gatgcagtcg ctcctttcgt tgaaaaagga gaagcggcaa ctttagaatg gctgacagaa
     3481 caagggacac aaaacattcg tcaattgaat gaagtgataa gagaaactgc catcccatgg
     3541 tatgagaaag taagtgaaag cacttgttaa tgtttctaat atattagtag tgataagaga
     3601 tatgtgtgat tataatttat cattattgaa actgggagga tattttatat gaataaaaga
     3661 ttgttagatt attcagcttc agattttttg aaagctaagc cgatggaatt aaagcaggca
     3721 attttggctt ctgaaggtag aacaattatg gcagaaaatg tgccaagtag ctgtccttac
     3781 atgggaaaat cagtgacaaa tgcagaattg gagagagctg ctggagctga tttaattttg
     3841 tttaatgcac tagatctttt taatcctcaa atttcaggtg tacctttaac tctaaaagag
     3901 aatccaataa tctggattaa aaaagcttta ggaagagcta ttggtgtaaa tttagaacct
     3961 gtagacaaag aagttttgat gagtgaaaat cgaactgaaa tttcaagtgg tagaatcgtt
     4021 tctcctgaga ctttaaaaaa ggcaaatgaa ttaggcttta attttatttg tttaactgga
     4081 aatccaggaa caggagtatc taatagaact attgagaaag caataacatt atccaaatca
     4141 atttttaatg gattaattat cgctggaaaa atgcatggtg ctggtgttga tgaaccaatt
     4201 atgaacttag atatagcaaa aagatttatt aaaacaggtg tagatatttt attagttcct
     4261 gctccataca ctgttccgta tttcatggaa agtgatttgc gaggaatcgt tgattatata
     4321 aaagatttta atagaaataa atctattgag gaaaaagttc tagtactaac ggctaatgga
     4381 acaagccaag actcttctga ccaagaaact attaaaaaaa ttgcattagc atcaaaagca
     4441 tgtggagctg atattcaaca cataggggat tctttaaatg gtatttgtct tccagaaaat
     4501 atttttgctt tgggtcaagc aattcgggga tatcgtcatc aaattattat gttaggaaaa
     4561 tctaattatc gttaattaag gaggaaatga aagatgatcg acaaagttca aaaaatagct
     4621 gcaaaaatta gtaatcaaag acatctacta gctttaagag acagcatggc tgcagttatg
     4681 ccattaatca ttattggttc cttttttatg ttattagcaa atttcccgat agaaggattt
     4741 acaaaatggt tatctgaaat tggagtacaa tcctttttga acaaagcatc agattcaaca
     4801 tttggtatta ttggattagc tgttacctac tctttgggac acaatctagc aaagacttat
     4861 ggtgtagact cattatcagc aggattatta tctttgagtg gatatgtttt acttacacct
     4921 ttattggatg cagatggttc tataggattt ccaacaaaat actttggtac ctcgggtctt
     4981 tttgttggta ttattgtagc acttgtatct acagaaattt tccggtggtt tgtacttaaa
     5041 aatattacaa ttaaaatgcc ggcaagcgtt ccaccaaatg taagccgagc tttcgttgct
     5101 attattcctg gcttttttgt cgttctacta tggtttattg ttgttgtaat ttgttataaa
     5161 cttggaattg aaaatgttca tgctcttatt gcagatacac tcgcaaaacc actatcttta
     5221 ctgacgaaaa ctttaccagg aattatattg gttatactta ttcaatgttt cttttggatg
     5281 tttggtattc atggtgcaca ggtaacgggg ccaataattg aaccgttatt attgcaaaac
     5341 tctgatgtaa atagaattgc ttatcaagct ggaaaagaac ttcctaacat tataacttat
     5401 gaattcttat ataactttgt tttttctggt ggtgcaggtt gtttatttgc acttgccatt
     5461 ttaacatttt tcttttcaaa gagtcaggaa aataaaactt taggtaagtt atcaatcgct
     5521 ccagtaagtt ttcaagtagc agagcccctt ctatttgggt ttccaactat attaaatata
     5581 aaaatgttaa ttccatttgt aactgcacca gtagtaacaa cattaattac ttatttttca
     5641 atgagtatgg gattagttgc aaaacctgta ggagcaacaa tcccatggac aactccaccg
     5701 ataattgccg gatttttagc ttctggtgga cgaataagtg gtgcagtgat tcaagtaata
     5761 acaattgcaa taaatgtttt gatatactat ccattcttta aattagatga taatgccaag
     5821 ctaaaaagcg aaaaaaatga ttagaactac ctatatgttt ctaactgtag ttaagt
//
LOCUS       DAFEEZ010000110         5708 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000110
VERSION     DAFEEZ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5708
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.116"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..193)
                     /locus_tag="LP245_002758"
     CDS             complement(<1..193)
                     /locus_tag="LP245_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520611.1"
                     /translation="MSKKGIIVNEWEKLNRISNRRLNAQTMCTPLKMQWSIDRITIVG
                     TLRENIYYHTPHDVLILDFE"
     gene            complement(736..2886)
                     /locus_tag="LP245_002759"
                     /pseudo
     CDS             complement(736..2886)
                     /locus_tag="LP245_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            3032..3607
                     /locus_tag="LP245_002760"
     CDS             3032..3607
                     /locus_tag="LP245_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1520612.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            3821..4516
                     /gene="vanR"
                     /locus_tag="LP245_002761"
     CDS             3821..4516
                     /gene="vanR"
                     /locus_tag="LP245_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBL1520613.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            4494..5648
                     /locus_tag="LP245_002762"
     CDS             4494..5648
                     /locus_tag="LP245_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBL1520614.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT         1785 a         1096 c         1083 g         1744 t
ORIGIN      
        1 gttcaaaatc taaaatcaac acatcatggg gagtgtgata ataaatattt tcccttaatg
       61 taccaacaat ggtaattcgg tcaattgacc attgcatttt taagggggtg cacatagttt
      121 gtgcatttaa ccgcctgtta gaaatacggt taagtttttc ccactcattt acgattatgc
      181 cttttttact caaaaatagc tcctcctcaa cgaaaaaaga gattcttgga aagaatttcc
      241 agagttcacg taactctaaa aatccacatc caaaaatctc tagcttgaag aaacctaaaa
      301 atattcgtat aatgaacttg agttacggaa ctaggtgaag tagtttccgt aaaggtcgag
      361 agtgcgtcaa cactgctcga ctattttttt actctttttt ctcattttct ttgattatag
      421 cactcctcta gaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc
      481 tcctcctgcc gaaatagaat ggcgctgcca gcatttattt cgttcagcta tcggctacac
      541 aatctaacac gaccgttccg ctaccagtcg ccttacaggc tccattttcg ctcctctaac
      601 gtgtttcacc gattgtgccg ataactaaac gaaataaacg ctaaaaccgc tcagaacgca
      661 aaatatgcca ttttagagct attgtagaaa atatagtttg aaatgcaatt ttcttctttc
      721 agctttttat ttcccacttg taaatcggta gatggtggct ccttttccag ttccataatg
      781 tggatttgca tctgcatgta gtgatgaaac acctagctgc attctcatac catctgacga
      841 agatgttgta ccgtcgcccc aatagaaagg caattgtaat ttatgatgaa agtttactaa
      901 tatggcttgg gctttattca tggcatcttc atacatgcgc cattgagata cattggctag
      961 ttgcttatat gtaagtccgg gtgtggcttc ggccatcttg ctcaagccaa tattcattcc
     1021 cattcctaaa agggcagcca tgataatgat tgtttcttcc ttatctggtt ttcgattatt
     1081 ggaagcatga gtgaattgct catgaaatcc tgttatatgg gccacatcca tgagtaaatc
     1141 agttaatttt attcttggta gcatctgata aaggcttgca ctaaattttt ttgcttcttc
     1201 tggaacatct ttttctaagc gtgcaagtga tagctttcct ttttcaagag aaaccccatc
     1261 taacttattg gaattggcag ctaaccactt taacctttca ttaaagctgc tggttctctc
     1321 cgttatataa tcttcgaatg ataaactaac tgataatctc gtattcccct tcgattgatt
     1381 ccatgtatct tccgaaaaca aatattcctc aaaatcccta tattgtctgc tgccaacaat
     1441 ggaaacatct cctgcccgaa catgctcccg aagttctgtt aaaacagcca tttcatagta
     1501 atgacgatta attgttgtac catcatcctc gtataaatgt cttttccatc gttttgaaat
     1561 aaaatccaca ggtgagtcat caggcacttt tcgctttcca gattcgttca ttcctcggat
     1621 aatctcaaca gcttgtaaaa gtggctcatt tgcctttgta gaatgaaatt ccaatactct
     1681 taatagcgtt ggcgtatatt ttcttagtga ataaaaccgt ttttgcagta agtctaaata
     1741 atcatagtcg gcaggacgtg caagttcctg agcctcttct actgaagaga caaaggtatt
     1801 ccattcaata accgattcta aaaccttaaa aacgtctaat ttttcctctc ttgctttaat
     1861 taatgcttgt ccgatgttcg taaagtgtat aactttctca tttagctttt taccgttttg
     1921 tttctggatt tcctcttgag ccttacgacc ttttgataac aaactaagta tttgcctatc
     1981 atgaatttca aacgctttat ccgttagctc ctgagtaagt tgtaataaat agatggttaa
     2041 tatcgaataa cgtttatttt cttgaaagtc acggaatgca tacggctcgt atcttgagcc
     2101 taagcgagac agctgcaaca ggcggttacg gtgcaaatga ctaatttgca ctgtttctaa
     2161 atccattcct cgtatgtatt cgagtcgttc tattattttt agaaaagttt cgggtgaagg
     2221 atgacccggt ggctctttta accaacccaa tatcgtttta ttggattcgg atggatgctg
     2281 cgaggtaata atcccttcaa gcttttcttt ttgctcattt gttagagatt tactaaccgt
     2341 attaaatagc ttcttttcag ccattgccct tgcttcccac accattcttt caagtgtagt
     2401 gatagcaggc agtataattt tgttttttct tagaaaatct atgcattcat gcagtagatg
     2461 aatggcatca ccattttcca aagctaattg atgaaggtac ttaaatgtca ttcgatattc
     2521 actcagggta aaagttacaa agtcgtattc acttcgaatt tctttcaaat gatcccaaag
     2581 tgtattttcc ctttgaggat aatgatcaag cgaggatgga ctaacaccaa tctgtttcga
     2641 tatatattgt atgaccgaat ctgggatgct tttgatatga gtgtatggcc aaccgggata
     2701 ccgaagaaca gctaattgaa cagcaaatcc taaacggttt tcttccctcc ttcgcttatt
     2761 aactatttct aaatcccgtt tggaaaaagt gaagtaggtc cccagtatcc attcatcttc
     2821 agggatttgc ataaaagcct gtctctgttc cggtgtaagc aattctctac ctctcgcaat
     2881 tttcattcag tatcattcca tttctgtatt ttcaatttat tagttcaatt atatatcaat
     2941 agagtgtact ctattgatac aaatgtagta gactgataaa atcatagtta agagcgtctc
     3001 ataagacttg tctcaaaaat gaggtgatat tttgcggaaa atcggttata ttcgtgtcag
     3061 ttcgactaac cagaatcctt caagacaatt tcagcagttg aacgagatcg gaatggatat
     3121 tatatatgaa gagaaagttt caggagcaac aaaggatcgc gagcaacttc aaaaagtgtt
     3181 agacgattta caggaagatg acatcattta tgttacagac ttaactcgaa tcactcgtag
     3241 tacacaagat ctatttgaat taatcgataa catacgagat aaaaaggcaa gtttaaaatc
     3301 actaaaagat acatggcttg atttatcaga agataatcca tacagccaat tcttaattac
     3361 tgtaatggct ggtgttaacc aattagagcg agatcttatt cggatgagac aacgtgaagg
     3421 gattgaattg gctaagaaag aaggaaagtt taaaggtcga ttaaagaagt atcataaaaa
     3481 tcacgcagga atgaattatg cggtaaagct atataaagaa ggaaatatga ctgtaaatca
     3541 aatttgtgaa attactaatg tatctagggc ttcattatac aggaaattat cagaagtgaa
     3601 taattagcca ttctgtattc cgctaatggg caatattttt aaagaagaaa aggaaactat
     3661 aaaatattaa cagcctccta gcgatgccga aaagcccttt gataaaaaaa gaatcatcat
     3721 cttaagaaat tcttagtcat ttattatgta aatgcttata aattcggccc tataatctga
     3781 taaattatta agggcaaact tatgtgaaag ggtgataact atgagcgata aaatacttat
     3841 tgtggatgat gaacatgaaa ttgccgattt ggttgaatta tacttaaaaa acgagaatta
     3901 tacggttttc aaatactata ccgccaaaga agcattggaa tgtatagaca agtctgagat
     3961 tgaccttgcc atattggaca tcatgcttcc cggcacaagc ggccttacta tctgtcaaaa
     4021 aataagggac aagcacacct atccgattat catgctgacc gggaaagata cagaggtaga
     4081 taaaattaca gggttaacaa tcggcgcgga tgattatata acgaagccct ttcgcccact
     4141 ggagttaatt gctcgggtaa aggcccagtt gcgccgatac aaaaaattca gtggagtaaa
     4201 ggagcagaac gaaaatgtta tcgtccactc cggccttgtc attaatgtta acacccatga
     4261 gtgttatctg aacgagaagc agttatccct tactcccacc gagttttcaa tactgcgaat
     4321 cctctgtgaa aacaagggga atgtggttag ctccgagctg ctatttcatg agatatgggg
     4381 cgacgaatat ttcagcaaga gcaacaacac catcaccgtg catatccggc atttgcgcga
     4441 aaaaatgaac gacaccattg ataatccgaa atatataaaa acggtatggg gggttggtta
     4501 taaaattgaa aaataaaaaa aacgactatt ccaaactaga acgaaaactt tacatgtata
     4561 tcgttgcaat tgttgtggta gcaattgtat tcgtgttgta tattcgttca atgatccgag
     4621 ggaaacttgg ggattggatc ttaagtattt tggaaaacaa atatgactta aatcacctgg
     4681 acgcgatgaa attatatcaa tattccatac ggaacaatat agatatcttt atttatgtgg
     4741 cgattgtcat tagtattctt attctatgtc gcgtcatgct ttcaaaattc gcaaaatact
     4801 ttgacgagat aaataccggc attgatgtac ttattcagaa cgaagataaa caaattgagc
     4861 tttctgcgga aatggatgtt atggaacaaa agctcaacac attaaaacgg actctggaaa
     4921 agcgagagca ggatgcaaag ctggccgaac aaagaaaaaa tgacgttgtt atgtacttgg
     4981 cgcacgatat taaaacgccc cttacatcca ttatcggtta tttgagcctg cttgacgagg
     5041 ctccagacat gccggtagat caaaaggcaa agtatgtgca tatcacgttg gacaaagcgt
     5101 atcgactcga acagctaatc gacgagtttt ttgagattac acggtataac ctacaaacga
     5161 taacgctaac aaaaacgcac atagacctat actatatgct ggtgcagatg accgatgaat
     5221 tttatcctca gctttccgca catggaaaac aggcggttat tcacgccccc gaggatctga
     5281 ccgtgtccgg cgaccctgat aaactcgcga gagtctttaa caacattttg aaaaacgccg
     5341 ctgcatacag tgaggataac agcatcattg acattaccgc gggcctctcc ggggatgtgg
     5401 tgtcaatcga attcaagaac actggaagca tcccaaaaga taagctagct gccatatttg
     5461 aaaagttcta taggctggac aatgctcgtt cttccgatac gggtggcgcg ggacttggat
     5521 tggcgattgc aaaagaaatt attgttcagc atggagggca gatttacgcg gaaagcaatg
     5581 ataactatac gacgtttagg gtagagcttc cagcgatgcc agacttggtt gataaaagga
     5641 ggtcctaaga gatgtatata attttggctc tttgtcaaat gatgttggta aagagaaatc
     5701 ttagaata
//
LOCUS       DAFEEZ010000111         5702 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000111
VERSION     DAFEEZ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.117"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..340)
                     /locus_tag="LP245_002763"
     CDS             complement(<1..340)
                     /locus_tag="LP245_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1520615.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYSFEEKIP
                     HFSTFGKNYVR"
     gene            complement(1671..2336)
                     /locus_tag="LP245_002764"
     CDS             complement(1671..2336)
                     /locus_tag="LP245_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1520616.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2516..4498
                     /locus_tag="LP245_002765"
     CDS             2516..4498
                     /locus_tag="LP245_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBL1520617.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4502..5140
                     /locus_tag="LP245_002766"
     CDS             4502..5140
                     /locus_tag="LP245_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1520618.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            5168..5596
                     /locus_tag="LP245_002767"
     CDS             5168..5596
                     /locus_tag="LP245_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520619.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
BASE COUNT         1881 a          879 c         1045 g         1897 t
ORIGIN      
        1 ggcgaacata attctttcca aaagttgaga aatgggggat tttctcctcg aaggagtagc
       61 ctaagaacca gcggtaagcg acattggtat cgacttcctt aatggtttgt cgcatggaac
      121 ggataccgaa taaatactga ataaacacca atttgatcag aatcactgga tcgatacttg
      181 ggcgacctaa atcggagtaa gtggcttcga cgattggata aataaattca aaatcaagcg
      241 cggcatcaat ctttcgaacg agatgatctt gaggaactag atcatcaatc gtaagcatcg
      301 caaattgatt tctaccattc gtattgtttt tagacatcat agctatcact ccttgcattc
      361 gttttcataa atctattata aaagaaaaga ctgtagatat catccataaa atggactttg
      421 tctacagtct gaggactacc tgtattagtc ctcttttttg accagatttt gaccagtcta
      481 ttttacattc taatatattc atatgagcta attttatgat taaatggtaa gtgtttcctt
      541 gtttgtttta gtttaaacta gtgtgtaatt taaaaatcta tatggaaggg tctgtggggt
      601 aatacttaaa taaaggctag gaacctgata acatcaaggt tcctagcctt tttataataa
      661 aatgaagcga aaataatttc ttttaaagag ccgagattat cagctatata agagtgaatt
      721 tgatgcaaaa aacagagccg aaacagtctt ggtgttcgta gctctgctta tatgtttcga
      781 atttaagaca aagagttggc aaaagatgtt gataaggaag ataagataac tgtgttatat
      841 aaactaggta actaactgta acaagctaat tttaagagat tcttattaga agacgtttag
      901 gaatataact aagaaaatga ttatacaggt aattgtcatt tcaataatgt tttctaattt
      961 tcgcgtcttt gttttaagaa aaaggccaga atcagttgga aaaaagttcg tacgatagtg
     1021 aagaggggca aaatttccta ctaatattcc cactaacaag agataaaacg gccaggttgg
     1081 tgtgattcct ctataaaaaa atgcccatgc taccgaaatc ccatagatta acaactgaac
     1141 aatttttaca atgaaaaaat tgttctgcca ttactcaaag tctcttcctc cttgtatcgt
     1201 ttatttgttt cattttatca ttatgatagg cgcttgaaca atccattttg tattttattg
     1261 agtactcttg gataaactac cagcgattat catatttatt tatgttactg taagccatca
     1321 tataaaagta aatgagcaga tcatagaaat ataaaaaaga actaaaattg atctaaatta
     1381 tgtgcagctt gactacgtac caatctatat tacttactag attggtcgtt aatctattcg
     1441 gatcgaatga gcaaaatatt tttgtgaatg tccatccttg attatgattc caaaaagaat
     1501 cattgggagg ctgtggcgta aatattatac tataagccag aaatacctat cattctgaac
     1561 ttttttattt aggaactttc atctcaaggc tttttcaatt aatttgtacc cctgtttttt
     1621 ggataagatc atgtgcattg attttttcta tctctacgtt catctcctac ttaatgccta
     1681 tctggctcct gagggcttct ttttaaggcg tcgtcatagt cttggctgag gatttcttgg
     1741 taatctgagg gaatggcttc ccaagtgagc aggcgaacgt tcatgacgtg ttttcctttg
     1801 tgtttgatta cagcatggtt tttctctttt tctacctctc cagcgtgaaa agacagccat
     1861 gtaccatggc caaagatatc attacatacc caacgttcga tggaattgtc cacgtatcct
     1921 acagggagtg tggtatagcc gatttgtggt ttcaaaaaag gattgaatcg atcgatcgtt
     1981 tcatttttgt attgataatt gataagaaaa agatagacca aacaaaagac gagcagaaag
     2041 aaagatagtg tctttttgag tgagaagggt tgttttgatg aataagattt cttgttaaca
     2101 agaggttcat ctggcaatgt tggttctatt gattcggtag ctgattcaat agaaggaaaa
     2161 tcaatcggca gacctaaagt atgatgtaaa agtgacagca tttcaaggtc tggcattgta
     2221 cgagaatttt cccaactaga aatcgtttta tcggaaacac caattttttc gcctaattct
     2281 ttttgcgtaa gcttacaatt tctgcggtaa gttcgtattt tttctccggt gttcatcttc
     2341 ttctcctttc gattctacag tatatagatt tattctacat gacctataca cttgatagat
     2401 acgttttttt gatgaaaaac ggtatgattt tatcaaagaa tcatttaagt aagggagagt
     2461 ggtgataatc aaaaaaaagt tcacagtttt actcacaatc atagtgaccg gtatcatgag
     2521 tggttttgcc ttggttagta taaataaaca ggtactctat cggacaaatg aatttttcca
     2581 tcaaacagat acttatactc cgattcgatt gccacaacat tttattgggc aagaagaata
     2641 tgagcagcta atcatggtat ttgaaaatgt ctcatcagaa actgagcttt cttatatgaa
     2701 aaaaacagta aatgaatcca atgaagtaga tacatcttgg aacttcaaga tacagccaaa
     2761 gcttgaaatg acattgtatt atcaagggga tgtcaaatct tctcacgaga aggtacccta
     2821 ttctaatacc tcctttcgcg taacgtccat tgaagaatcg atcaaaataa aagattttga
     2881 aggtgaattt ttcttgatga cgagagaaaa agaagcctat gaacggttca tttcactatt
     2941 cactgatcga ttcaatcaag catttcacac tgattatgcc actaatattt ttgaagactt
     3001 tgaaaatagc tattcgtatt cggttatttc aaatacagac gtatataatt atcgagtgta
     3061 tttaactatt ggattgattc ttttattcct tttgttatca tcctttttct tattgatgaa
     3121 taaagaaatc agtttattgt tgaataatga cttttcatta catcaagtat tgtggtgttt
     3181 attggggaaa aagaaaatca ttattacatt cataattgca ggaatcattg gtggttttat
     3241 ttttatgtat tataaggagc aatttcttta tttgttccag atgtacgttt tcttgttcag
     3301 cggaatatat ggtatctctt tgatttctct tttattagtt gaaaaaatcg cttcgttaag
     3361 agaagcgttc aactatatcc aatacattct ttttacattt ggattgttgt tttctcttct
     3421 tttgaccgtt gccaatgtcg aattagcaac tatcgttttt tcttcttcac agttagctgt
     3481 ttcccatgaa ccaccaaaag aaatcgctgg tgaggactat catgtatttt atccagtaac
     3541 catcgggaaa aaccacgtgg attttattta ttccaatcgt tttgcatcag cagcagatca
     3601 ggaattatat gaaactttga ataaaaacgg aagtatatta gtcaatgtat cagattactt
     3661 gaatgaagaa aatgaacagt ttggcagagg gataaaaata aatctgaatt atcttaagaa
     3721 atttcctttg attgatgtct ctggaaggtt gatccaaata accgaaaaag aaacgcaccc
     3781 tgttatattg atccctgaac gatatagaca tacagattta aaaaatgacc tggcgcaaat
     3841 aacagaatat tatcaagaaa tcagtgaaaa agaaccgaaa tttctattta taaaaaacaa
     3901 tcaacccatt tatacattta ttccttctat cccctggatc gaacattatc cggttgttga
     3961 aatactgaca ttgaaaaaca gtatgtattt ggaaagaaat attctcagcg gagaaatcta
     4021 tccaccgtta aagatcaaga taggctcttt gtcgaaagaa aggttatttg agctgattga
     4081 agaaagtcag ttacgtgata acttgcagtt atcatttccg tatactcaga ctgaagagat
     4141 agctgtcaaa gtgttaagca gatcatttca ttacttgata cagatatttt tactcacttt
     4201 cttttctttc ttcttgttga gctatgtcat gttatgcata tattttgtct acaattgtcg
     4261 gaaaatcgct atctttcgtt caagtggtta ttcgctcttt gaaacgtata aagatttctt
     4321 catgatgaac ctcatcaaat ggggaacgac aagtgtaatc ttcctttttc ttatagaaag
     4381 agagcctaaa tatcttttta atattttttt ctttagcttc attgatttta ttctttcagt
     4441 tgtttttatt ttgtctacag aaaagaaaag tcagttattg ctgatgaatg gaggttaaca
     4501 attggagccg ttgatagtga taaaaggtgc gaaaaaaatc attcgaaaca aaacgattct
     4561 tcatttggat cgtttcactg cggatgctgg ggatcttgtg actgttgttg gagaaagtgg
     4621 agcaggtaaa agtacgttat tgaatatatt aggattgaat gatcagttca gttcaggaca
     4681 attctatttg ttcgatcaag agacgaaaca attaactggg agagagaagc gcttgataaa
     4741 aagaaatacc atatcttttc tttttcaaga ttttgggttg attgaatatg aaacaatcga
     4801 ttttaattta gatattggat tgaagttttc gaatttaaat gtttcagata agcgaacagc
     4861 aaagtatgag gcattgaaaa aagtaaatat aaacaagaag ctaagtacgc ctatctacac
     4921 attatctggt ggtgagaagc aaagaatcgc ctgtgcgaga gtcttattga agaatagcaa
     4981 aatcatttta gccgatgaac cgactgggtc attggataaa agaaataagg ataaagtagt
     5041 tgaaatctta tcgcaacaag cttcccaagg tacgttagtt atcgtagtca cgcatgatcc
     5101 atatctgacc aaaataggaa acaagaagat catgctttaa aaatcaaaaa ggaaaggatg
     5161 tcgttttatg aaaaaagcag ttattatttg tgcactaggg ataggttttg ttggaggaaa
     5221 cgctatgtca tctgaagtgg aagcaaattc agttcacggt gaaatctatt acaaatcttt
     5281 aaagccagga gagattcatt ttgatgctaa aggtaatatt attaagtcaa atttaccagt
     5341 agaccgggaa atttctagaa cagcaattaa tcatagctct ggaagatggg tttattatag
     5401 tgatacaact tgtacgagaa aaacaggtca ttctaaccac tatagtcgtg tctataatcg
     5461 tcacggtgca aaagcgaaag ttggaaactc tattcgatca gcaaatgcaa caaaaggagt
     5521 atgggcctat gcaagtgcga caggaaatag aactgacaca ttctcatgtt ggtacaatcc
     5581 aaccggttgg tattaagtat ccaaaagttt atataaaata gaaaaaacat ataatgaaac
     5641 agcgttaaaa gttatttttg gtagttttaa tatattcatt tttagttgta taaaaatata
     5701 tc
//
LOCUS       DAFEEZ010000112         5681 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000112
VERSION     DAFEEZ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5681
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.118"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            133..1287
                     /locus_tag="LP245_002768"
     CDS             133..1287
                     /locus_tag="LP245_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBL1520620.1"
                     /translation="MEYSEERQRLAYVRLYGGILHLRDSVRISEKEKIKITEMYTSIN
                     GELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQ
                     REMLLDALLEISDSDPLLQYYVDSTTHEIILSFLGKVQMEVISALLQEKYHVEIELKE
                     PTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSF
                     QNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKA
                     GTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEY
                     RSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            1385..2758
                     /gene="tet(L)"
                     /locus_tag="LP245_002769"
     CDS             1385..2758
                     /gene="tet(L)"
                     /locus_tag="LP245_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HBL1520621.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            3322..4584
                     /locus_tag="LP245_002770"
     CDS             3322..4584
                     /locus_tag="LP245_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBL1520622.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            4829..>5681
                     /locus_tag="LP245_002771"
     CDS             4829..>5681
                     /locus_tag="LP245_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HBL1520623.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHK"
BASE COUNT         1954 a          805 c         1167 g         1755 t
ORIGIN      
        1 tccttgtacc ctgtttatca tggaagcgca aaaagcaaca tagggattga gcagcttata
       61 gaagtgataa cgaataaatt ttattcatca acatacagaa agaagtctga actttgcgga
      121 aatgtcttca aaattgaata ttcggaagaa agacaacgtc ttgcatatgt acgcctttat
      181 ggcggaatcc tgcatttgcg ggattcggtt agaatatcgg aaaaggaaaa aataaaaatt
      241 acagaaatgt atacttcaat aaatggtgaa ttatgtaaaa ttgataaggc ttattccggg
      301 gaaattgtta ttttgcaaaa tgagtttttg aagctaaata gtgttcttgg agatacaaag
      361 ctattgccac agagagagag aattgaaaat ccgctccctc tgctgcaaac aactgttgaa
      421 ccgagcaaac ctcaacaaag ggaaatgtta cttgatgcac ttttagaaat ctccgacagt
      481 gacccgcttc tacaatatta tgtggattct acgacacatg aaattatact ttctttctta
      541 gggaaagtac aaatggaagt gattagtgca ctgttgcaag aaaagtatca tgtggagata
      601 gaactaaaag agcctacagt catttatatg gagagaccgt taaaaaatgc agaatatacc
      661 attcacatcg aagtgccgcc aaatcctttc tgggcttcca ttggtttatc tgtatcaccg
      721 cttccgttgg gaagtggaat gcagtatgag agctcggttt ctcttggata cttaaatcaa
      781 tcatttcaaa atgcagttat ggaagggata cgctatggtt gcgaacaagg attatatggt
      841 tggaatgtga cggattgtaa aatctgtttt aagtatggct tatactatag ccctgttagt
      901 accccagcag attttcggat gcttgctcct attgtattgg aacaagtctt aaaaaaagct
      961 ggaacagaat tgttagagcc atatcttagt tttaaaattt atgcgccaca ggaatatctt
     1021 tcacgagcat acaacgatgc tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa
     1081 aataatgagg tcattcttag tggagaaatc cctgctcggt gtattcaaga atatcgtagt
     1141 gatttaactt tctttacaaa tggacgtagt gtttgtttaa cagagttaaa agggtaccat
     1201 gttactaccg gtgaacctgt ttgccagccc cgtcgtccaa atagtcggat agataaagta
     1261 cgatatatgt tcaataaaat aacttagtgt attttatgtt gttatataaa tatggtttct
     1321 tgttaaataa gatgaaatat tttttaataa agatttgaat taaagtgtaa aggaggaatt
     1381 aattatgaag tgtaatgaat gtaacagggt taaatacaac caaattttaa tttggctttg
     1441 cgttttatct ttttttagcg tattaaatga aatggttttg aacgtctcat tacctgatat
     1501 tgcaaatgat tttaataaac cacctgcgag tacaaactgg gtgaacacag cctttatgtt
     1561 aaccttttcc attggaacag ctgtatatgg aaagctatct gatcaattag gcatcaaaag
     1621 gttactccta tttggaatta taataaattg tttcgggtcg gtaattgggt ttgttggcca
     1681 ttctttcttt tccttactta ttatggctcg ttttattcaa ggggctggtg cagctgcatt
     1741 tccagcactc gtaatggttg tagttgcgcg ctatattcca aaggaaaata ggggtaaagc
     1801 atttggtctt attggatcga tagtagccat gggagaagga gtcggtccag cgattggtgg
     1861 aatgatagcc cattatattc attggtccta tcttctactc attcctatga taacaattat
     1921 cactgttccg tttcttatga aattattaaa gaaagaagta aggataaaag gtcattttga
     1981 tatcaaagga attatactaa tgtctgtagg cattgtattt tttatgttgt ttacaacatc
     2041 atatagcatt tcttttctta tcgttagcgt gctgtcattc ctgatatttg taaaacatat
     2101 caggaaagta acagatcctt ttgttgatcc cggattaggg aaaaatatac cttttatgat
     2161 tggagttctt tgtgggggaa ttatatttgg aacagtagca gggtttgtct ctatggttcc
     2221 ttatatgatg aaagatgttc accagctaag tactgccgaa atcggaagtg taattatttt
     2281 ccctggaaca atgagtgtca ttattttcgg ctacattggt gggatacttg ttgatagaag
     2341 aggtccttta tacgtgttaa acatcggagt tacatttctt tctgttagct ttttaactgc
     2401 ttcctttctt ttagaaacaa catcatggtt catgacaatt ataatcgtat ttgttttagg
     2461 tgggctttcg ttcaccaaaa cagttatatc aacaattgtt tcaagtagct tgaaacagca
     2521 ggaagctggt gctggaatga gtttgcttaa ctttaccagc tttttatcag agggaacagg
     2581 tattgcaatt gtaggtggtt tattatccat acccttactt gatcaaaggt tgttacctat
     2641 ggaagttgat cagtcaactt atctgtatag taatttgtta ttactttttt caggaatcat
     2701 tgtcattagt tggctggtta ccttgaatgt atataaacat tctcaaaggg atttctaaat
     2761 cgttaaggga tcaactttgg gagagagttc aaaattgatc ctttttttat aacaggaatt
     2821 caaatctttt tgttccatta aagggcgcga ttgctgaata aaagatacga gagacctctc
     2881 ttgtatcttt tttattttga gtggttttgt ccgttacact agaaaaccga aagacaataa
     2941 aaattttatt cttgctgagt ctggctttcg gtaagctaga caaaacggac aaaataaaaa
     3001 ttggcaaggg tttaaaggtg gagatttttt gagtgatctt ctcaaaaaat actacctgtc
     3061 ccttgctgat ttttaaacga gcacgagagc aaaacccccc tttgctgagg tggcagaggg
     3121 caggtttttt tgtttctttt ttctcgtaaa aaaaagaaag gtcttaaagg ttttatggtt
     3181 ttggtcggca ctgccgacag cctcgcagag cacacacttt atgaatataa agtatagtgt
     3241 gttatacttt acttggaagt ggttgccgga aagagcgaaa atgcctcaca tttgtgccac
     3301 ctaaaaagga gcgatttaca tatgagttat gcagtttgta gaatgcaaaa agtgaaatca
     3361 gctggactaa aaggcatgca atttcataat caaagagagc gaaaaagtag aacgaatgat
     3421 gatattgacc atgagcgaac acgtgaaaat tatgatttga aaaatgataa aaatattgat
     3481 tacaacgaac gtgtcaaaga aattattgaa tcacaaaaaa caggtacaag aaaaacgagg
     3541 aaagatgctg ttcttgtaaa tgagttgcta gtaacatctg accgagattt ttttgagcaa
     3601 ctggatccag gagaacaaaa acgatttttt gaggaaagtt ataaattatt ttccgaacga
     3661 tatggcaagc aaaatattgc ttatgcaaca gttcataatg atgagcaaac ccctcacatg
     3721 catttaggtg ttgtgcctat gcgtgatgga aaactgcaag gaaaaaatgt gtttaatcgt
     3781 caagaactgt tatggctaca agataaattc cccgagcata tgaaaaaaca gggttttgag
     3841 ttgaagcgtg gtgaacgtgg ctctgaccgt aaacatattg agacagctaa atttaaaaaa
     3901 caaactttgg aaaaagagat tgattttcta gaaaaaaatt tagcagttaa aaaagatgaa
     3961 tggactgctt atagcgataa agttaaatca gatttagaag taccagcgaa acgacacatg
     4021 aaaagtgttg aagtgccaac gggtgaaaag tccatgtttg gtttgggaaa agaaataatg
     4081 aaaacagaaa agaaaccaac caaaaatgtt gttatatcgg agcgtgatta taaaaactta
     4141 gtgactgctg cgagagataa cgataggtta aaacagcatg ttagaaatct catgagtact
     4201 gatatggcga gagaatataa aaaattaagt aaagaacatg ggcaagttaa agaaaaatat
     4261 agtggtcttg tagagcgatt taatgaaaat gtaaatgatt ataatgagtt gcttgaagaa
     4321 aacaagtctt taaagtctaa aataagcgat ttaaagcgtg atgtgagttt aatctatgaa
     4381 agcactaagg aattccttaa ggaacgtaca gacggcttaa aagcctttaa aaacgttttt
     4441 aaggggtttg tagacaaggt aaaggataaa acagcacaat tccaagaaaa acacgattta
     4501 gaacctaaaa agaacgaatt tgaactaact cataaccgag aggtaaaaaa agaacgaagt
     4561 cgagatcagg gaatgagttt ataaaataaa aaaagcacct gaaaaggtgt ctttttttga
     4621 tggttttgaa cttgttcttt cttatcttga tatatataga aataacgtca tttttatttt
     4681 agttgctgaa aggtgcgttg aagtgttggt atgtatgtgt tttaaagtat tgaaaaccct
     4741 taaaattggt tgcacagaaa aaccccatct gttaaagtta taagtgacca aacaaataac
     4801 taaatagatg ggggtttctt ttaatattat gtgtcctaat agtagcattt attcagatga
     4861 aaaatcaagg gttttagtgg acaagacaaa aagtggaaaa gtgagaccat ggagagaaaa
     4921 gaaaatcgct aatgttgatt actttgaact tctgcatatt cttgaattta aaaaggctga
     4981 aagagtaaaa gattgtgctg aaatattaga gtataaacaa aatcgtgaaa caggcgaaag
     5041 aaagttgtat cgagtgtggt tttgtaaatc caggctttgt ccaatgtgca actggaggag
     5101 agcaatgaaa catggcattc agtcacaaaa ggttgttgct gaagttatta aacaaaagcc
     5161 aacagttcgt tggttgtttc tcacattaac agttaaaaat gtttatgatg gcgaagaatt
     5221 aaataagagt ttgtcagata tggctcaaag atttcgccga atgatgcaat ataaaaaaat
     5281 taataaaaat cttgttggtt ttatgcgtgc aacggaagtg acaataaata ataaagataa
     5341 ttcttataat cagcacatgc atgtattggt atgtgtggaa ccaacttatt ttaagaatac
     5401 agaaaactac gtgaatcaaa aacaatggat tcaattttgg aaaaaggcaa tgaaattaga
     5461 ctatgatcca aatgtaaaag ttcaaatgat tcgaccgaaa aataaatata aatcggatat
     5521 acaatcggca attgacgaaa ctgcaaaata tcctgtaaag gatacggatt ttatgaccga
     5581 tgatgaagaa aagaatttga aacgtttgtc tgatttggag gaaggtttac accgtaaaag
     5641 gttaatctcc tatggtggtt tgttaaaaga aatacataaa a
//
LOCUS       DAFEEZ010000113         5569 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.119, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000113
VERSION     DAFEEZ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.119"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(205..660)
                     /locus_tag="LP245_002772"
     CDS             complement(205..660)
                     /locus_tag="LP245_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520624.1"
                     /translation="MKKQLFKTFLLSTSILTFGSAITPSGAVFANENNISDIATYSDD
                     EYYYVLDEPVIQTRTWSKPQSWSIAKGSRTYLGIETHSRGTKLSVSANVFGMKIEIAR
                     NTSASGKFKKYRQNARITVTYRVYRKVDNKYIRTQTSTANTQYIDYIPA"
     gene            complement(1280..1696)
                     /locus_tag="LP245_002773"
     CDS             complement(1280..1696)
                     /locus_tag="LP245_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520625.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
     gene            complement(1698..1979)
                     /locus_tag="LP245_002774"
     CDS             complement(1698..1979)
                     /locus_tag="LP245_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520626.1"
                     /translation="MDILVRNINPKIIARIDKRCQELTTKTGKKWSRNKYLKVLIESD
                     FDRQLMNYKKDQFDLLLEKFIAIQTENTNILNDYVHTNNQLIETLIGGI"
     gene            complement(2355..2879)
                     /locus_tag="LP245_002775"
     CDS             complement(2355..2879)
                     /locus_tag="LP245_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBL1520627.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTENHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDHQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKAEKKWWQFWQ"
     gene            complement(2896..3864)
                     /locus_tag="LP245_002776"
     CDS             complement(2896..3864)
                     /locus_tag="LP245_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL1520628.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            complement(5031..5186)
                     /locus_tag="LP245_002777"
     CDS             complement(5031..5186)
                     /locus_tag="LP245_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002402449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520629.1"
                     /translation="MKLTKLTISLVIIAGIILYFVLPANQFFLYFGIPTILIVNGVRI
                     FEQRKKM"
     gene            complement(5205..>5569)
                     /locus_tag="LP245_002778"
     CDS             complement(5205..>5569)
                     /locus_tag="LP245_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL1520630.1"
                     /translation="FSVLFLINILNTSFSEGINPNEVNGSLLLFFLNAATYGAFLEEG
                     IFRFCMIDPQANKKQQYISILISSFLFSIVHGGGLSIFFIGIILSFVYIQTKNIWYSI
                     VAHGFYNTIGILIYLISI"
BASE COUNT         1675 a          907 c          942 g         2045 t
ORIGIN      
        1 aaaaaaaact atatttaaag agttttttta gatttacttc tttgaattca cgaatgaagg
       61 tagaatgaaa tagtataatt attagcacta aaaaaaatat atcactatgt tcaaataaaa
      121 aatatatatt tgacggtact cctaatgatg ggatagcaaa ggtcaaaacc aagtaagcaa
      181 tactaattat ccattttatt gtcattaggc aggaatataa tcaatatatt gtgtatttgc
      241 tgtagaagtt tgagtacgaa tatatttatt atctacctta cgataaactc tgtaggttac
      301 agttattctt gcattttgac gatatttttt aaattttcca cttgcagaag tgtttctggc
      361 tatttcgatt ttcatcccaa atacatttgc actgacagat aactttgtac ctcgactatg
      421 agtttctata cctaaataag tacggcttcc tttagcaatt gaccagcttt gaggtttaga
      481 ccaagtcctt gtttgaataa ctggttcgtc taacacatag tagtactcat catcagaata
      541 agtggctata tcagaaatgt tgttctcatt agcgaatacc gctccgctag gagtaatagc
      601 agaaccaaaa gttaaaatag aagtagataa taaaaaggtt ttaaataact gttttttcat
      661 caaaatcacc tcgaatataa gatacttaag aaaacgcttt ctttatataa ttagaataat
      721 caggaaattt aatgttgtca agagggttta ttttataaaa gctgttatat taaaggttag
      781 tagacataat gtacactatg ccaagtagcc cctctaccaa tggatagaga cgctcacttt
      841 gtgattttta attggtctag ctagttacta gcttctaatg cttgatttta cgcgatttct
      901 cttttttagt tctttgtgca tttttatctg tcatttttta aagacttgtt atttttgaga
      961 ggatttgata tgcttttttt gtctttctct agttcttcac tttgtaatat ttttatgttg
     1021 atgaatagga taatctcatt ttgggctgct cgtgagagca gtcttttttt gtttcagggt
     1081 acgtcctatt ctttggattt ccgcgctatt aaataaccga tacttgggga ttggggtagc
     1141 gccccaaaat acaaaaagaa gaagttgcat aagcggattt ttcttttttt tcgcaagttg
     1201 gtaccaactt gcaaatcttg ctggaagact gatccctaaa aagaaatcga ggaatttttt
     1261 tagggatcgg tttctttttt tatcttttta gaaagtttgt tgggtcaaaa tttccagaag
     1321 taaaggtttg attggtttct ttttgacgat ttttgggttg atttcgtcgg gaaggattga
     1381 gttgattttc aattttttct ttcacttctt gatacacttt agaatttgta ccgataagaa
     1441 caccagtatc ttttagatat aaatcagcaa attctgccat gatttctgtc atgatagaaa
     1501 tttcttttcc catggcattg agttttgctt ggttactggt tgtggttgta ttggtatcag
     1561 gttcataact catacataaa aaacgaatgg cttctgaata attgttgacg tctggatttt
     1621 tttcgatgat ggaatctaaa acgtcaacgt gactgggata aagggttacg tgtttttgaa
     1681 cagaagtttt tctcatgtta tattcctccg ataagtgttt caatgagttg gttgtttgtg
     1741 tgaacatagt cattcagtat gttcgtattt tctgtttgaa tggcaataaa tttttcgagt
     1801 aataaatcga attgatcttt tttgtaattc ataagttgac ggtcaaaatc actttcgatt
     1861 agaactttta gatatttatt tcgactccat tttttgcccg ttttggttgt gagttcctga
     1921 caacgtttat ctattcttgc aataattttg ggattgatat ttcgaactaa aatgtccatg
     1981 gaaattttcc tttcgtatca gcgtataatt tatgtatacc atacaaatat agtatttgta
     2041 tagctatttt tcgccaaaac actatacata gcctagccac aatggcaaaa aagtgatagc
     2101 aaattttttt ctgagaaacg tgataggcac agcctatcta gcacctttcg taagaaagtg
     2161 ataccacgtt tccttatgct ctttcaaaat tcagaaaaat cagctgtaaa acgagtgcag
     2221 tccgagtaag attcaacgaa aaaacgggga ttggggcgcc accaaaatat cgcaacatgg
     2281 gtccatgttg ctctgctcgc aaaagcaaaa agaagaataa aaccagcaat ttttattaat
     2341 ttaaattgct ggttttattg ccagaattgc caccattttt tctccgcctt tgattgtttt
     2401 tctatcgatt ctgtttcttc agaaagagtc gttgatttat tttccgaaga ttcttccgta
     2461 taagtcaact gtagttgttc ctgcagtttc tcgatttgtt ggttggcttg cagggtgagt
     2521 tgttgttggt ggtcgagtaa tttttgcatt tgttttattt gctcgtcttt ttcttgtagt
     2581 tgcatatctt tttgatttaa ctgttgttct aggagagaaa ggacttctaa ttcgggaact
     2641 tggttggcgt ttttgtggtt ttcggttttc gttttttcgc caactagttg ttgatttgag
     2701 ttttcgtttt cgttaaaaaa cattgatttt atagcctttt gtccggtttc attaatcaca
     2761 aacttgtttc cgattttcga aaaccaaagt tttcgatttt cgtcagaaac ttttttgtta
     2821 attgctgttt tactaactcc taattcttca gcaagttctt tgattgtttt ttctgtcata
     2881 aaatctaaaa acccctcaat ctttgaataa gttttgaaga ttgtctaata agtctttttt
     2941 tagttctgaa ggaatatcgg aatttatctc tgatttttgt gcattatttt ctttattttg
     3001 ggtattttgt tctctttcta acttttctaa ctgttgtaaa agttccaatt ttcgcttttg
     3061 ttctttgatt ttttcttgta atgaagtagg tgctttttca gattgaactt gttggttagc
     3121 tagttctaat gctttgtttt gttcttcttt tgttggggca tgtttgttaa agtcgtctga
     3181 tttttttatc tcaggtttaa atgtaaattg atagccaatg acaggctttc cccgtccttt
     3241 tccgtatttc tttttgattg ttaaaccttt aaagattgcg gttagttctt gtcgtattgg
     3301 attgaacaca cgttgatcaa tcgtaccttg gttgtaactt ttaggaatat caagtaattc
     3361 atgaaagtct tcttttgaaa aataagcgaa acctttggtt ctgtattgtt ttagtaatcg
     3421 aaacattgtt tttgaataac tgctttctaa ttcattgaat tgttggagag aatagcgcac
     3481 ccattcttca agattattaa gtaagggtaa ggctttttca tgaacttgta tttcagcaaa
     3541 aggaatatca gattttccgt cgattttaaa ttgattaaat aaaacaaaac gttcacgttg
     3601 caaaccgtca gcacttcttc taccaaaacg taaatccatt aatttgtcat acgttgtttc
     3661 taaatcatct atgaatcgaa catttgcagt tgctttataa ttgcttaaat cttttaattg
     3721 ctcgaatgta aattgtactt ttttatcacc tacatcacgc attcttgata cgatagaaaa
     3781 gaacaaattc atttcgactg gtgtaaattt tcgcaacgga attgtattta attcatgatg
     3841 atactttacg atttcattag acatatttaa aatagctcct ttcttactcg cacaagagat
     3901 acacgttatg aaatacaaaa tgcctgttta tctacatctt atattaacat cgtcgatgta
     3961 ctaattcaat gtacaaacag acaaaacgat gtagataaac agacaaaacg atgtagataa
     4021 acagacaaaa cgatgtagat aaacagacaa aacgatgtag ataaaagcgt cattcccttg
     4081 ggagagtaag gatatagccg acggtaaaga ggtttaaaaa gaggtttaaa aagagattat
     4141 aaaagagggg gacaaaattt cccgcctaaa aaaccacttc ttttttctcc aaacagattc
     4201 gcgcattttt ctcaactggg aatcttactc cctacagtcg cttaaaaagg tgtgatcgct
     4261 ctgctctcac attatactgc gcagtcgctt ccggctcctt tgctaaaaat gttcataagg
     4321 aactctttga gaagctatga gccttcgttt gagacgtttt aagacagtct tagtataaat
     4381 cccttatctt gttcttaaag cgccttacag gcggtcaggg caagccctaa caaccctaaa
     4441 gttgtctgaa tgccctctaa aattcgattt aagcactctt aaacctactc ttatatattt
     4501 atatacttag acgtttcaaa cgtcttaaaa cgcaaattag agcttgataa agatatttgc
     4561 tcgtgtgccg acttttttaa aagtctaggc acacgccatg acaaagctga aataaactgc
     4621 ttcagctttg tcatggcgga ttcgctcact tgaaaaagtg ttcatttcgc tcgattatta
     4681 gcatatattt tttaactttt tttgctagcc aaattttgca ttagttcgct cataaatccc
     4741 accctttcag tacgtcctac ggacgtatcg ttcgtaatgt gaaagtacct ttaaaggtac
     4801 tttctacaaa actcactaaa gtgtttggca agctctatat ttgctagcca aatacctacg
     4861 tatttggtgc aaataaccgc ttgtcaaagg ggcgcaagct cccccttgaa tcccccctca
     4921 aaacccacgc tccacaatac aaaaaaggct agcaaatgct agccactttt tgtaaagttt
     4981 cgcttgtttc accttcggtg aaattgttgc tttgcaacga tcaggtagag ctacattttt
     5041 tttcgttgtt caaatattct tacgccattt actattaaaa tcgtaggtat tccaaagtaa
     5101 agaaaaaatt gattagcagg taatacaaaa tataaaataa taccagcaat aattaccaaa
     5161 cttatagtaa gttttgttaa tttcatgaag tatgccacct tatcttatat agatatcaaa
     5221 tagattaata tgccgattgt attataaaat ccatgagcaa ctatggaata ccatatattt
     5281 tttgtttgta tataaacaaa acttaaaata ataccaataa agaaaatact taggcctccc
     5341 ccatgaacaa tagaaaacag aaaagaagaa attagtattg aaatatattg ttgttttttg
     5401 tttgcttgag gatcaatcat acaaaatcga aaaattcctt cttctaaaaa agctccataa
     5461 gtagcagcat ttaaaaagaa taaaaggaga gaaccattta cttcattagg atttatacct
     5521 tctgaaaaag atgtatttag aatattgatt aggaataaaa cagagaatg
//
LOCUS       DAFEEZ010000114         5463 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000114
VERSION     DAFEEZ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.120"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..933
                     /locus_tag="LP245_002779"
     CDS             <1..933
                     /locus_tag="LP245_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1520631.1"
                     /translation="RWKETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESLA
                     IDILTFLTGISSRDGERFPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHI
                     ESFTDYDFAHLLFSDGYVEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAM
                     LIVISTFALDFIHTDRSIFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVT
                     QNTDDLLDEKLKNNLGLKFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCL
                     ISDLYGRVGVIQFHPVFEELLHAFDTRPPVRKEV"
     gene            936..3119
                     /locus_tag="LP245_002780"
     CDS             936..3119
                     /locus_tag="LP245_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBL1520632.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            3116..4117
                     /locus_tag="LP245_002781"
     CDS             3116..4117
                     /locus_tag="LP245_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBL1520633.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            4132..5046
                     /locus_tag="LP245_002782"
     CDS             4132..5046
                     /locus_tag="LP245_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1520634.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            5291..5407
                     /locus_tag="LP245_002783"
     CDS             5291..5407
                     /locus_tag="LP245_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HBL1520635.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
BASE COUNT         1727 a         1048 c         1154 g         1534 t
ORIGIN      
        1 agatggaaag aaaccttgcc agagatttcc catgaaatca atatcgtcaa tctgacttct
       61 gatgagaaaa acaaaggctt acttgaccct tatgtaatta tgaaaaatac caaagattct
      121 gaatcactgg ctattgatat tttgacattc cttacgggga tttcctctcg tgatggggaa
      181 cgcttcccaa tccttagaaa agccattcgt gcagtaacca atagtgaagt gcgagggttg
      241 atgaaagtga ttgaagaatt acgggttgag aatacgccac taagtaccag catagccgac
      301 catatcgaaa gttttacaga ctatgacttt gcccatctgc tttttagtga tggttatgta
      361 gagcagtcta tcagccttga aaaacaactg aacattatac aggttgccga cttggtactt
      421 cctgacaagg aaacttcctt tgaggaatat accacaatgg agttactatc ggtagcaatg
      481 ctgattgtca ttagtacctt tgcgttggac tttatccata cagaccgaag tattttcaag
      541 attgtagact tagacgaagc atggagcttc ttacaggtgg cacaagggaa aacactatct
      601 atgaagctgg ttcgtgctgg tcgtgctatg aacgctgggg tatatttcgt gacccaaaat
      661 acagatgacc tcttagatga aaaactgaaa aataacctcg gcttaaaatt tgcctttcgt
      721 tccactgacc ttaacgagat taaaaaaacc cttgcctttt ttggtgtaga cccagaggac
      781 gaaaacaatc agaagcgatt gcgtgatttg gaaaacgggc aatgccttat cagtgattta
      841 tatggtcgtg tcggtgtgat acagttccac cctgtatttg aagaactgct ccatgccttt
      901 gataccagac cacctgtgcg aaaagaggtg taaatgtgaa accatcaata ttaaacagaa
      961 taaaatcaaa ctggacgctg aaacgtctag gtaaagtggc aatgacagtg gctttcacac
     1021 ttgtgattgc catttttctt ttagccatgc tgggaacggt ggttcaagct gcgggcttgg
     1081 tagatgatac ggtcaatgtg gcaaatgaat acagccgata cccacttgaa aactatcaac
     1141 tggattttta tgtggataat agctggggct ggctaccgtg gaactggtcg gacggaattg
     1201 gaaaacaagt catgtatgga ctatatgcca ttaccaattt tatttggaca atcagtcttt
     1261 atgtttccaa tgcgacgggt tacttagtac aggaagccta ttccttagac ttcatttccg
     1321 ctacagcaga ttccattggc aagaatatgc agacccttgc aggggttacg cctagtggac
     1381 tatcaacaga gggtttctat gttggattcc ttttactctt gattttggtt cttggggttt
     1441 atgttgccta tacaggactg ataaagagag aaaccacaaa ggcaattcat gccctcatga
     1501 attttgtgct ggtttttatc ctatcggctt cctttattgc ctacgctccc gactacatta
     1561 aaaaaatcaa tgacttttca tcagacatca gcaacgctag tttgtcactg ggtacaaaaa
     1621 ttgtcatgcc ccattcagat agtcaaggca aggacagtgt ggacttgata cgtgacagcc
     1681 tattttccat acaggttcag caaccgtggc tactgcttca atataacagt tcagacattg
     1741 aaagtattgg tattgaccgt gtggaaagcc tgctctcaac cagtccagat tccaacaatg
     1801 gggaagacag agaaaaaatt gttgcggaag aaattgaaga tagaagcaat accaatatga
     1861 cgattacaaa gacgattaac cgtttaggta cagtcttctt cctatttgtc ttcaatattg
     1921 ggatttccat atttgtattc ctattaacag gaatcatgat tttctcgcag gtacttttta
     1981 tcatctatgc tatgtttctg cctgtgagct ttattttaag catgattcca tcatttgatg
     2041 gtatgtcaaa acgagccata acaaagctct ttaataccat tttgacacga gctggaatca
     2101 cattgattat tacgacagca tttagtattt caaccatgct ctatacctta tcggctggtt
     2161 atccgttctt tttgattgct tttctacaga ttgtgacctt tgcaggaatc tactttaagc
     2221 tgggcgattt aatgagtatg ttttctctac agagtaacga ttctcaaagt gtgggaagtc
     2281 gtatgatgag aaaacctcgt atgcttatgc acgctcacat gcaccgtcta cagcggaaac
     2341 ttggacgctc cgtgactgct ttaggggctg ggtctgccat tgccagtgct acgggtaaaa
     2401 aaggacagtc gggttcggga agttctgcga gtacacaagc agatcactct cgaccaaacg
     2461 ggcaggaaaa atcaacacta ggaaagcgta tcggtcaaac catcggtaca gtagctgata
     2521 ccaaagacag aatggtagat actgctggta atttgaaaga acaggttaag gatttgccga
     2581 ccaatgcaag atatgcagta tatcaaggaa aatctaaagt gacggataat gtccatgatt
     2641 taaccagaag tatttctcaa accaaagcgg ataaagccag tggacgcaag aaacagcagg
     2701 aacaaagacg gaaaaccatt gcggagcgtc gctctgaaat ggaacaggtc aaacagaaaa
     2761 aacagccagc ttcttccgtt catgaaagac cagccactaa gcaagaacaa tctcatgatg
     2821 gacagacttc aaggcaaaca actgtacagg cttcctatag ggaatctcaa caagccaaac
     2881 aagagcgtcc aacagttaag tccgattctt caagtttaaa aacggaacgt caaagtaata
     2941 cagttcaaga aagaacggtt caaaagccag taacttcaac tgcaccaaca gatagagctt
     3001 cacaacgttc aatcacaaaa gaacgtcagt ctactgttca aagagtacca ctacaaaata
     3061 caaaaagtag accaccaatc aaaaccgcca ccattaagaa aggcagtaag aaaccatgaa
     3121 gctgaaaact ttagtgattg gtggttcggg attattcttg atggtcttct cactgcttct
     3181 gtttgtcgcc attttatttt cagatgaaca agatggcggt ttttccaaca ttcactatgg
     3241 cggtgtggat gtttccgcag aagtgctggc tcataagcct atggtagaaa aagttgccaa
     3301 agaatatgga attgaagaat acgtcaatat acttcttgcg attatacagg tggaatcggg
     3361 tggtacagca gaagatgtta tgcagtcctc ggaatccctc ggtcttccac ctaattcatt
     3421 gagtacagaa gaatccatta agcaaggtgt gaagtatttc agtgagttat tagccagtag
     3481 cgaaaggctt ggtgtagatt tagaatcggt tatccagtcc tacaattatg gtggtggttt
     3541 cttaggatat gtggctaatc gtgggaataa atataccttt gaactggctc aaagtttctc
     3601 aaaagagtat tcgggtgacg aaaaagtgtc ttaccccaat cccatagcca tacctatcaa
     3661 tgggggctgg cgatacaatt acgggaatat gttttatgtg caactggtaa cgcagtatct
     3721 tgtcacaaca gagtttgatg atgatacagt acaagccatc atggacgaag ctctgaaatt
     3781 tgaaggctgg aagtatgtct atggcggagc ttccccgact acctcttttg attgtagcgg
     3841 actgacacaa tggacgtatg gaaaagctgg aatcaactta ccacgaacag cacaacagca
     3901 atatgatgta acccggcata tcccattatt ggaagcaaaa gccggcgatt tggttttctt
     3961 tcattctacc tataacgctg gctcttatat tactcatatc gggatttatt taggcgataa
     4021 ccgtatgttt catgcaggcg accctatcgg ttatgccgac ttaacaagct cttactggca
     4081 acagcattta gtgggagcag gacgaatcaa acaataagaa aggacgattc aatgatgaaa
     4141 ttcggaaaaa atcagaatac agaaaaacag acaccaaagg aaaagaaacc tcgtgtctat
     4201 aaggtcaatc ctcgtaaaaa ggttgtgatt gtcctatggg tacttttagg acttagtttc
     4261 agctttgcga tattcaagca ctttacagcc attgataccc ataccattca tgaaaccacc
     4321 atcatagaaa aggaatatgt cgatactcat catgtggaaa attttgtaga gaactttgcg
     4381 aaagtctact attcatggga actaaacgac aagtccattg ataatcgcat agaaaacctg
     4441 aaagcatatc tgacagagga acttcaagct ctgaatgtcg atacagttcg taaagatatt
     4501 cctgtatcgt cttctgtaaa aggatttcag atatggacgg tagaagcaga tggcgacaat
     4561 caatttgatg taacctacag tgtagaccaa ctcattacag agggggaaaa tacaaagacc
     4621 gtccactctg cttatatagt gagtgtctat gtagacagta ctggaaatat ggtcctcatt
     4681 aagaatccga ccattactag cataccaaag aaatcagact ataaaccaaa agctattgaa
     4741 agtgagggta cggttgattc cattacaacc aatgaaatca atgagttttt aacgacgttc
     4801 ttcaagctct atcctacagc gacagccagt gaactttcct actatgtgaa tgacgggata
     4861 ttaaaaccaa tcggaaaaga gtacatcttt caagaactgg taaatcctat ttacaatcgt
     4921 aaggataatc aagtcacggt atcgctgaca gtggagtata tcgaccagca gaccaaagca
     4981 acgcaggtat ctcaatttga tttggtactt gaaaagaacg ggagtaattg gaagattata
     5041 gaataacaaa tattggtaca ttattacagc tattttgtaa tcacgtactc tctttgataa
     5101 aaaattggag attcctttac aaatatgctc ttacgtgcta ttatttaagt atctatttaa
     5161 aaggagttaa taaatatgcg gcaaggtatt cttaaataaa ctgtcaattt gatagtggga
     5221 acaaataatt ggatgtcctt ttttaggagg gcttagtttt ttgcacccag tttaagaata
     5281 cctttatcat gtgattctaa agtatccgga gaatatctgt atgctttgta tgcctatggt
     5341 tatgcataaa aatcccagtg ataagagtat ttatcactgg gatttttatg cccttttggg
     5401 cttttgaatg gaggaaaatc acatgaaaat tattaatatt ggagttttag ctcatgttga
     5461 tgc
//
LOCUS       DAFEEZ010000115         5460 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.121, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000115
VERSION     DAFEEZ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.121"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..177
                     /locus_tag="LP245_002784"
     CDS             <1..177
                     /locus_tag="LP245_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520636.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
     gene            190..690
                     /locus_tag="LP245_002785"
     CDS             190..690
                     /locus_tag="LP245_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL1520637.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            787..2634
                     /locus_tag="LP245_002786"
     CDS             787..2634
                     /locus_tag="LP245_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBL1520638.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2637..3533
                     /locus_tag="LP245_002787"
     CDS             2637..3533
                     /locus_tag="LP245_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL1520639.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNFYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3583..3972
                     /locus_tag="LP245_002788"
     CDS             3583..3972
                     /locus_tag="LP245_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1520640.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3959..>5460
                     /locus_tag="LP245_002789"
     CDS             3959..>5460
                     /locus_tag="LP245_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1520641.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPLSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKG"
BASE COUNT         1864 a          789 c         1159 g         1648 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg gggcatggtt taccccaccc gtcgattttg atgaagtgaa agaacggatt
      301 ggattaaatg acgaatatga agagtacgca attcatgatt atgaactgcc ttttgagatt
      361 gatgagtata caccaattga ggaaattaat cggttgtgtg gtttagcgga agagcttaaa
      421 ggaacgccaa ttggtgaggt cgcttcagag attcaacatg ccttcttcaa ttctttcgag
      481 gaaatggtag agcatgtgga tgatatcatc tattatcccg attgtaatga catgagtgat
      541 gtagcgtatt acttgattgt agaagctggt gatttaggcg aagtaccaga acacttgaag
      601 acgtatattg attttgatgc gtgtggtcga gacttggaga ttggcgggaa ttatttggtt
      661 acgagtcgag gggtttttga actaatgtaa atcatttgtt agaattgacc agaaatttct
      721 atcgtacttt tacttttcta tttgatatac tgaaatagaa aatatttgtt gataggggtg
      781 ttactaatgg ttggcaataa gtggtacaaa tgtgatcttc atattcattc aactgcgagt
      841 cagtgctttc aggataaaaa ggttactgct aaggaatggg tagaagaatg tttaaacaaa
      901 ggactcgatt gtgttgcatt aactgatcac aatacagggg aaaatattga tgaatataag
      961 aaagtggcta tcgaaaatgg cttagatttt tttcctggag tggaattaac gtgtggagaa
     1021 aatggaactc atttactagt cctatttgat aaaagtgcat gtacaaatga tatctctgat
     1081 ttcttaacca agatgggtat aaaaagagag gattgggcca gcgctgcagc ttgctcaatg
     1141 aaatcagttt tagaagttat tgattttgct gagcacgagg gcttgctcgt tattcctgca
     1201 catatagatg agtttaatgg aatttcttca gcaaaatttg gaaatctagg aaagatattt
     1261 gaatcagaaa atatatatgc agtacagacg gttcaaaaag aattttttga aaatcgctca
     1321 caaatgattc cctcatctaa gcgtgacact atctatgata gtgtgaatgc cagatatgat
     1381 ggtagagttg gaaaagatac tttggaatct tggtataaat cagttgttga ggcagaaaaa
     1441 aataatatga catttcttag cttttctgat aacccacact cgaaaggaaa ttcaaaacat
     1501 ggactttggg gaataggcac aagatattcc tatataaaaa tgaaggacga acctgacttg
     1561 ggatcacttc gcgatgcttt aatgctaggc gaaactcgag ttcattctga tttttctaat
     1621 ttctccatta atgaaaatga agttttattg gaaaaattaa gcttttctgg gaccactctt
     1681 agcacaaaag aagttgtagt cgaattcagc gataatttaa cttcaattat tggaggaaga
     1741 ggaacaggca aatcttgtat tacaagattc ttggtctatg tccttggaaa ggaagcagaa
     1801 cttgatcaat tttctgaaat acaaagtgat tatcagaact ttgcacaaat tgaacataat
     1861 ggctctggaa tatttttgaa ggatacaatt gtgaaactga atattttcta taaggggaca
     1921 aaatatcaaa taataagaac acaggataga cattctattt atgaatttac acaagagaat
     1981 ggtctggttg aaaaagaaac agaacggttg agaatgattt ccgataaggt gagtatatac
     2041 tctcaaaaac aaatttatga aatttcaaaa aatcaaacta gtatactaga attactagat
     2101 ggatataact ctgatttgat ttcagagtat aaaaatgaga ttgaaacatg tgtaaacgaa
     2161 ataagaaaat taaattggga tattgtttct gtgaaaaaag aaatacaaga taaggcgaag
     2221 gtagagcttg aaattgaaga tttaaaaaaa caagtagaaa agctatctca taagagttat
     2281 aaagatgttt atgatgagta ttcaaaagag acagatattt atagggaact gaaacgtgat
     2341 gtggaggcac ttaaggaaat tcccaaaaat ctaactgata gtgttgacaa aattgacttt
     2401 ggcaatggta taaaagttac agacgaaatt gatgaacacc gcggagaatt gattaagaat
     2461 ttagtgacca atcgggctaa gattcaaaca ataattaatg aaatgtcaga tgaaattgat
     2521 agttatagag cagagctgaa taaatcagat tggaaagtta actataatga ggtttcaaag
     2581 aggtatcaaa gaggtatcaa aaacttagtg aagagttatc tcaagatgaa ttaaaaatgt
     2641 tacaaaacct tgattcttta tatcaatctt tatcaaaaac tgaagagcga ttggaagaaa
     2701 ttattcaaca agaaataaag cttaaagatt accaagttga ggttgactca gcaatgtcaa
     2761 gaatgaataa atcatatcaa aatttctatt ctgagagaag tagttcctcg cgcgaaattt
     2821 tttctgatat tacaggaata gaggctacta ttcaaccaaa tagggatttc aataattatg
     2881 ttaaagagct cagagcttgt attaataagg aggacacttt tgacagtgag tttggatctc
     2941 ttattgataa gctgacaaaa aattccatta ctaatcaaga tatatataat gacatacttg
     3001 atataagagt tagtggggaa agtagtattt tttcagataa aaaattaatc aattctataa
     3061 gaaaattgaa tgatgcacaa gttcttgaat tacaaaccct taagccaaat gatttagtag
     3121 ttatccgact tgaactaaat ggaaaaaaag ttagtttatc gaatgctagt gctggtcaaa
     3181 agacatctgc aattctttct atgattttgg cgtatggaaa ttcaccactc atattggatc
     3241 agcctgaaga tgatttggat agtcaattaa ttaataactt aatcgtaaga agtatcatta
     3301 caaaaaagga aaacagacaa attttaattg taactcataa tgcaaatatc ccagttaatg
     3361 gtgattcaga atggttgatt agcatgggag attcaaaaga aatatcggct gatcagtgcg
     3421 ggtcggtaga tgaacccaat atcaagccaa gaatatgtac tgtgatggaa ggtggcgagg
     3481 atgcttttac aaatagagcg aaacgctatg gttttaaaca aattgtagaa taacactaga
     3541 gggtgagaca tattattatg tccgcccttt ttaggaggaa aaatgaaaaa aataaaaagc
     3601 tataccagta tctgggcagt tgaaaaagtc atttacgcaa tcaatgattt tcagttgcct
     3661 tttcctgtga cttttaacca aatggcttgg ttcgttttat ctttactgtt tgtcatcgta
     3721 tttgcccatg tgcctccact atctatgata gaggaggtct ttttaaaata cttaggcata
     3781 ccggtggctg tcacttggtt tatgtcgcaa aagacgtttg atggcaagaa accactggga
     3841 tttttacgat cctttatcag ctatcacttg cgatttaagg tgacttttgc aggaaagaaa
     3901 gtcaaagaac agaagaaacg atgggatgaa cccagtactc ttgtaaggag tgtgaactat
     3961 gtatccgatt aagtatattg aaaataatct cgtctttaac caagaaggcg agtgttttgc
     4021 ctactatgaa ttagtgcctt acaattactc ctttttgtca cccgaacaga aatttcaagt
     4081 gcatgataac tttcgccaac taattgcgca aaatcgtgaa ggcaagatcc atgcgttaca
     4141 aattgccaca gaaagtagta ttcgcgccac acaagaacga tcaaaaaaag aaattaccgg
     4201 tagactcaaa gaagtagcga aacaacgaat tgatatacag acagatgcat tagtatccat
     4261 gattggcgat agtcagattg attatcgctt ttttattggc tttaaactaa ttgcgacaga
     4321 tgaagaagtc aatctaaaga gtctcaagaa atctttcttt tctgggcttc aagaatttgt
     4381 ctatggagtg aatcatcatt tgatgggcga ttttgtttcc ttatccaatg aagaaattcg
     4441 ctgctattct aagcttgaaa aattaatgga aagcaaattg gctcgaagat ttaaagtcag
     4501 gcgagtcaca ccgagtgacc tgacgtattt gattgaacat atttatggcg aaaaagggat
     4561 accgtttgaa gaatacgaat ttcagctacc aaagaaaaag ctaaaatcag aaacactggt
     4621 gaaacgttat gacttattac gtccaaatcg ttgtttaatt gaagaaaaac caaggtgctt
     4681 acggatggaa catgagaatc atgagtcgta cgtagcgtat ttaacaatta atacaattgt
     4741 gggggagatg gaatttcctt cctcagaact tttctattac cagcaacaac aatttacatt
     4801 cccaatcgac acaagtatga atgtagagat tgtgacgaat aaaaaggctt tagctaccgt
     4861 tcgtaataag aaaaaagaac tgaaagattt agacaatcat gcttaccaat ctgacaatga
     4921 aacgaattcc aatgtcttag atgctttgga ttccgtggat gaattggaaa ccaccttgga
     4981 tcagtcaaaa gaatctatgt acaaactgag ttatgtggtt cgagtgagtg ccgaatcagt
     5041 ggatgaacta aagcgacgct gtgatgaagt gctcgatttt tatgatgata ccaatgtaaa
     5101 actagtccgg ccctttggcg atatgatggg gctacatgaa gaattcttac ccttaagtaa
     5161 acgatatatg aacgactata ttcagtatgt tacgtctgat tttttggcgg ggcttggttt
     5221 tggggctact cagatgctag gagaattaga agggatttac tttggctaca atgtggatac
     5281 aggtcgtaat gtttacctga aaccggcatt ggcttcacaa ggagtcaagg gttcagtaac
     5341 caatgcgctg gccgccgctt tcctgggttc tcttggtgga ggtaaatcct ttagtaacaa
     5401 tctcttagtc tactatgctg ttttgttcgg tggtcaagct gtgattgtcg atccaaaagg
//
LOCUS       DAFEEZ010000116         5345 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.122, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000116
VERSION     DAFEEZ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.122"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            37..939
                     /locus_tag="LP245_002790"
     CDS             37..939
                     /locus_tag="LP245_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1520642.1"
                     /translation="MNIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISS
                     RDSEKFPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLL
                     FSDGSVTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFI
                     HSDRSIFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMK
                     NNIGLKFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQ
                     FHPIFEELLHAFDTRPPVRNEVEE"
     gene            936..2963
                     /locus_tag="LP245_002791"
     CDS             936..2963
                     /locus_tag="LP245_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520643.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            2960..3982
                     /locus_tag="LP245_002792"
     CDS             2960..3982
                     /locus_tag="LP245_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBL1520644.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            3999..4928
                     /locus_tag="LP245_002793"
     CDS             3999..4928
                     /locus_tag="LP245_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1520645.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            5173..5289
                     /locus_tag="LP245_002794"
     CDS             5173..5289
                     /locus_tag="LP245_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HBL1520646.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
BASE COUNT         1755 a          948 c         1091 g         1551 t
ORIGIN      
        1 gaatggaaag aaaccttacc tgatattgcc catgaaatca atattgttaa tctcacgagt
       61 gagaacgaca ataaagggtt acttgaccct tatgtgattt taaaactccc gaaagattca
      121 gaaagccttg ccattgatat tctcacgttc ttaacaggta tttccagccg agatagcgag
      181 aagtttcctg tcctgcgtaa agctattcgg agtgtaactc aaagcaaaca acgagggttg
      241 ttattggtga ttgatgaatt gcgaaaagaa gatacgccca tcagcaatag tattgctgac
      301 catatcgaaa gctttgtcga ttatgatttt gcccatctgt tattcagtga tggcagtgtc
      361 acccaatcca ttagcttgga aaaacaactc aatattattc aagtggcaga tttggtctta
      421 cccgattcca atagctcttt tgaagaatac actaccatgg aattattaag tgtggcaatg
      481 ctgattgtca ttagtacctt tgctttagac tttatccact ctgaccgttc catttttaaa
      541 attgttgacc ttgatgaggc ttggagtttt ttacaagtgg cacaaggaaa agctctatct
      601 atgcgattgg ttcgagcagg acgtgccatg aatgcagggg tctatttcgt tactcaaaac
      661 gcggacgatt tactagatga aaagatgaag aataatattg gcttgaaatt tgcctttcgt
      721 tccactgacc tagtggaaat caaaaagacc ttagaatttt ttggtgtgga caaggaagat
      781 gaaaacaatc agaaacgctt acgtgaatta gaaaatggac aatgtttagt ttcagacatc
      841 tatggtcgtg taggggttat gcagtttcac ccgatttttg aagagttgct tcatgccttt
      901 gataccagac cgcctgtgcg aaatgaggtg gaagaatgac acaaaaacaa aagaaatttc
      961 ttcactatag ttggataacg ctcctttgtg tgggcgttat tttactttta ttaggcacgc
     1021 tgggcaatgc agtacaagcg acaggcttag ttgatgaaac cattgataca agcaatgaat
     1081 actccaagta tggtttgaat caatatcagc ttgattatta tgtggacaat agctggggct
     1141 ggcttccatg gaattggagt gatggcatag gacaatcggt gatgtatgga ttgtatgcca
     1201 ttactaattt tatttggaca atttctcttt atctatcgaa cgccacaggt tatttggtga
     1261 aagaagccta tgccttagat ttcattagtc aaacatccca agcaattggc gaaaacatgc
     1321 agacgattgc aggcattaca ccgaatggct tttccagttc agggttttat gtcggtttcc
     1381 tccttctttt tattctcatt gttggaatct atgttgccta tacaggattg gttaagcgag
     1441 aaacgacgaa agtgatacga gctgttttaa actttgtcgt ggtgtttatt ctatcggctt
     1501 cctttattgc gtatgcaccc gattatattg cgaaaatcaa tgatttttcc aaagatgtca
     1561 gtaccgccag tctgaatatt gggacaaaaa ttgttcttcc taacacggat agtcaaggga
     1621 aagacagtgt ggacatgata cgtgacagct tattctctgt tcaagtaaag caaccatggc
     1681 tattgcttca atatggctcc actgatgtag aagcgttagg ggaagaacgt gtggaaagtt
     1741 tattgtctac cagtccagat acaaacaatg gtgaagatag agaaaatgta gtgattgaag
     1801 aaattgaaga tcatgacaat acctatttaa ccctaccgaa gacgatttcc agattaggaa
     1861 cagtcttctt tttgtttgta ttcaatattg gtatctcgat ttttgttttc cttctaacag
     1921 gaatcatgat tttttcgcaa gtgctattta ttattttcgc tatgtttttg ccaatcagtt
     1981 tcctattaag tatgttgccg agttttgatg gcatgggcag gcatgccatt accaagttat
     2041 ttaatgtgat tatgacaagg gctggtatta ccttgattat taccgttgcc tttagtattt
     2101 ccactatgct ttattcgctg tcagcaagtt ctcccttttt catgattatg tttttacaaa
     2161 ttgtgacctt tgcagggatt tattttaaac tgggcgattt aatgagccta ttcactttac
     2221 aaagcaacga ctctcaaaac atgggcagac aagtgtttcg cagacctcgt caaatgatga
     2281 atcgacaaac cagaagattt caacgcagta tgagtaagat ttttcgtgga aaagcagggt
     2341 caacgaagca aaagacaatg acaacaaagc agaatcaaac caataaagct aaccatactc
     2401 gtcaaaatga acggactaca ccaaagaaag aaacagcact ttccaatgtg aaaaagcaac
     2461 aaggcggtat cgggcaacga ttaggtgaaa agacagccca tgtattggac acgaaaaatc
     2521 gtctagtcaa taaaagaaag caggcaaaac aacagataca ggcgacacca acccatgtca
     2581 aatatgccct tcatcaagga aaagagaatg tcactcataa tgtaacagac tttaaacaat
     2641 ctatggcaga taccaaagct caacgcaaac aacagcgtat gaaccagcag gagcaaaaac
     2701 gaaagaacat tgctcaaaag cgtttggagc tggataaagc aaaagaaaaa agacgaaaag
     2761 aaaacccatc atctcctgtt cagaataacc agcagcatgt tcgcaagcgt cagcaaaccg
     2821 tcacgcctgt tttgtcacaa aacactaaac gtgaaaatca tcagcgacca ttgaaaaaag
     2881 agcaaaaaca aaagacacca ccgaagcaat tcaatcagag gaagctaaat aaaagaacgg
     2941 ataagcgagg acaacaaaca tgaagctaaa aataacagtg atttgtagtg tggtcttctc
     3001 tctcttcttt tttctcttat tattcctagt cattttcttt gcagatgata cggacagtgg
     3061 cgaaaacaac aaggattctt ctattccaca aggcggtgtg accgtttcac cagaagtgtt
     3121 ggcacaccgt ccgttgattg aaaaatatgg taaggaatat gggattgaag actatgtttc
     3181 ttatatctta gccattatgc aagtggaatc gggcggtaca gcagaagatg ttatgcaaag
     3241 ttccgaatct ttgggtttac cgcccaacag tttgagtacc gaagagtcca tcaaacaagg
     3301 ggttaaatat ttcagtgaat tattaaccag tgcagaacaa caaggagtgg atatagattc
     3361 tgttatccaa tcttataatt atggcggtgg ctttttaaat tatgtgagga gtcatgggaa
     3421 aaaatatacc tatgaattag ccgaacagtt ttctaaagag aagtcgggtg gtcaaaaagc
     3481 agactatccc aatcctatag ccatacctgt gaatggtggt tggcgatata actatggaaa
     3541 tcagttttat gttcagttgg tttcacaata cctaaccgac acttccccaa cagaatttga
     3601 tgatgaaacc gtgcaagtca ttatggacga agccttgaaa tacgaagggt ttccctatgt
     3661 ctttggaggg gcgtcgccta ccacctcttt tgattgtagt ggcttaatac aatgggtgta
     3721 tgacaaagct ggcatttctc tccctcgtgt cgcccaagat cagtatgacg ctacgcaaga
     3781 aatctctatg gaagaagccc aagcaggcga ccttatcttc tttcattcaa cctataatgc
     3841 aggcacatat gtgactcatg tggcgatata tttagaggga aatcgctttt atcatgcagg
     3901 cgacccaatc ggttatggcg acttaagcag tcgttattgg caagaccatc tgattggggc
     3961 tagacgtgtt attcataact aagaaaggaa tgaatcaaat gattataaaa atcgagcgaa
     4021 aagaaaagaa ggagaaacca aagaaatcta aaaaaccgag caagcaaaga aaagttccga
     4081 tgattaaagt tggcacgcat aagaaattaa cctttgtttt atgggtttta ttgattggta
     4141 gtgtcggatt tggaatctat aaaaatttta ctgccattga cactcatact gtccgtgaaa
     4201 cagaaatcat taaacagcag attgtcgata ccaaccaagt agaaagtttt gtgaaatcct
     4261 ttgcgaaaga ctacttttcg tggcaacaat cccaagaagc cattgataaa cgaaatgaaa
     4321 aattgaccca ttatttgacg gaagaattgc aggtattaaa tgaagaaatg attcgtaagg
     4381 atattcctac tagttctagt gtgaacgata tacaggtgtg gcaggtttct caagtgaatg
     4441 agaacacctt tgaggtactg ttttctgttg aacaagttat taccgaagac aaagacaagg
     4501 aaactatatc gtctagcttt catgtggttg tccatataga tgaatcagat aatatggtta
     4561 ttatcaaaaa tccgacaatg agtaagaaac ctcaaaaatc ggactaccaa cccaaacagc
     4621 tagaaagtga ccatacagta gatacagaaa cgatggacga aatcactagc tttttagaaa
     4681 cgttcttcca gctctatcct accgccacag aaaaagaatt gacttactat gtaagtaatc
     4741 atgtgttacc tatgattaac aaggaatatg ttttcgagga attggtgaat cctatcttta
     4801 ccagaaaaga taaccaagta atcgtgaatg tcgctgtgaa atatttagat caagaaacaa
     4861 aggcaaccca aatctcgcaa tttgagttga tattagaaaa acaagataat tggaagattg
     4921 taaaataaca aatattggta catgattaca gatactttgt aatcatgtac tctttttgat
     4981 aaaaaattgg agattccttt acaaatatgc tcttacgtgc tattatttaa gtgactattt
     5041 aaaaggagtt aataaatatg cggcaaggta ttcttaaata aactgtcaat ttgatagcgg
     5101 gaacaaataa ttagatgtcc ttttttagga gggcttagtt ttttgtaccc agtttaagaa
     5161 tacctttatc atgtgattct aaagtatcca gagaatatct gtatgctttg tatacctatg
     5221 gttatgcata aaaatcccag tgataaaagt atttatcact gggattttta tgcccttttg
     5281 ggtttttgaa tggaggaaaa tcacatgaaa attattaata ttggagtttt agctcatgtt
     5341 gatgc
//
LOCUS       DAFEEZ010000117         5341 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000117
VERSION     DAFEEZ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.123"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(62..280)
                     /locus_tag="LP245_002795"
                     /pseudo
     CDS             complement(62..280)
                     /locus_tag="LP245_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(546..740)
                     /locus_tag="LP245_002796"
     CDS             complement(546..740)
                     /locus_tag="LP245_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520647.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(840..926)
                     /locus_tag="LP245_002797"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="LP245_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2092..3132
                     /locus_tag="LP245_002798"
     CDS             2092..3132
                     /locus_tag="LP245_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL1520648.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYE
                     SSPSTITKDWLE"
     gene            3956..4288
                     /locus_tag="LP245_002799"
     CDS             3956..4288
                     /locus_tag="LP245_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBL1520649.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4907..5248
                     /locus_tag="LP245_002800"
     CDS             4907..5248
                     /locus_tag="LP245_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBL1520650.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1943 a          728 c          900 g         1770 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattgta ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt attacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttctgattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaaatttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtggta tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gaaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt catggagtaa cattaaaatt
     3181 aaaaattttt tattattcta attatattac gaatattaca aaataatagc tattttaata
     3241 gaatttataa gttaaaatat tatgataaaa atcacaaacg tagcctttta cgtcataagt
     3301 gttaaaagaa ataattaatt tcaaatatag aaaagggaac gtatgtttgc atactccttt
     3361 tttttgagtt ataataatac gcgaagagag ataatttcat tatttaaaca agctaaaaat
     3421 cttgatatta cttcttttca ggcaatacga atattattcg cttacatttt ttgtataaat
     3481 ttaattgtct gctatgcttg tgatgaattg attttcgttc tgcacttttg gatgataaat
     3541 ttggacaatt gaaaatacaa aaaaaagaaa ggcggtatga actcggaagg ctggtaacct
     3601 tcgtcagcgt tcatacacgg cattaagatt tggcccttaa tgcgttaacc tttcagtgtt
     3661 acggtattac ccgcaatgga tttagtataa cagatattca aaagtgatac cacttttttt
     3721 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcacaatgtt
     3781 ataaaaatgt ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat
     3841 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
     3901 aaaataacaa gaaaaacttg ttaaaaatat ttaaagaaat tgggtggttt attttatgtc
     3961 atatacagga attttgagtc tcaaagatat ttgtcactac ggtaaacggt gtaccgctac
     4021 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
     4081 atatataatc cagaaagaca aagtctcaga ggaaatgatt tattacattg ggaaacaaaa
     4141 gcaaataatt ttaaaagatc ctatcccctt aaaagagcta tatccaacaa tcaaacatgt
     4201 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
     4261 aaaagggatg gggcgtttga tcggctgaat tgatcattct cataacttgt attttatcgt
     4321 ttttcgcttg cttgaaaata ttgtcgagac ttctaaagga acttagagtc actagaaaaa
     4381 taaggagtag acttgatcta tcaacaattc ccttcgggga gtgacggggt aggttttaac
     4441 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgcgc ttgtttggat agtggtgaaa
     4501 tgaatttgtg taaataataa gcgcagagta aacaagaggg aatttagaag ttagacaagt
     4561 tagaatagcg tctagattaa tcatgagcag ctactaaggg atctagactt tgacgcaaac
     4621 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg
     4681 tgctgcagta catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac
     4741 cgctgtctac tagggtttct cgtttcggac gccataaacg agtcgaaatt ttttatgtat
     4801 ttttaagtaa acgaaaaacg ataaaatatg aacaagtcct gaataaagtg aaaaaattga
     4861 tataaaacat agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga
     4921 tccgaatata cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa
     4981 aggatttgtg acgtttagaa gaggcggaaa ttgtaaagga ttagatgttt tagcattaga
     5041 cgaggatgat ttatacgatc aaacattgac tgataatcca attggattcg gcttgctacc
     5101 tgaagatgat gaaggtaatg aatggtttaa aatgacgctt atgaatgata atggagacga
     5161 attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagct ttgaaatcat
     5221 tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc
     5281 ttagaaggag tcacgatgat taataaaaag gtagtattac cttaggcatt gagtaaggaa
     5341 t
//
LOCUS       DAFEEZ010000118         5275 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.124, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000118
VERSION     DAFEEZ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.124"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            439..537
                     /locus_tag="LP245_002801"
     CDS             439..537
                     /locus_tag="LP245_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBL1520651.1"
                     /translation="MYEKFLTLVVAPLFVGLVIELVSHWLDEKDDN"
     gene            complement(691..1188)
                     /locus_tag="LP245_002802"
     CDS             complement(691..1188)
                     /locus_tag="LP245_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520652.1"
                     /translation="MKLFFEKMGWHILPVVIILVGSYSLFCIFRSILEKFEEPKLKRV
                     VFALCFAFLALFVSVGISSYRPDVALSVRPKISKIEQLEAKAEAKQKKIDKISDQLEQ
                     ALKIASQEKLKTFNPKDYPSEVITADWVQKNRDVIATLPDKELKDRYTKRFDDVESYF
                     ELNSQ"
     gene            complement(1216..1671)
                     /locus_tag="LP245_002803"
     CDS             complement(1216..1671)
                     /locus_tag="LP245_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520653.1"
                     /translation="MPLDDFASKQELQKVKQELAEIKQQNQEVIETLKSLDNSVKQGY
                     IKVRGGEDIPKMSELKAEMNRYATYVQKRTAEIDQKLDSYGNISKSVSDELSRQVRPQ
                     VQKFLANDDRATAEELKQNRIANLMSVLASVGLFIGGTAILIVSVLKLL"
     gene            complement(1679..2665)
                     /locus_tag="LP245_002804"
     CDS             complement(1679..2665)
                     /locus_tag="LP245_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBL1520654.1"
                     /translation="MGATLALKGGKRGASALIGYVNRHGKLDRDRIYTHKLSAENKLA
                     QTQLEATRRIFAKTGGIQAFHWVQSFDNSFDKNNPADVQKAHEIGAKLVDEIAKSYPN
                     HEIYMGTHTDSESGYIHNHIVFASIDTETGKKFHSDTEVGYHLQDLNDKVLLSFGIEQ
                     PKEKFKQVDFEMHAEGKMSNREKMKHMILGAQDMSTDFDSFKKNLQEAYAVEVYEYNK
                     GKRIGFKWVDDEGKDFTIGGRKLGSDFERPAIERTLEFSQQKQEKEVEKPLETKPKVT
                     NDDFSISGLKNLANDIRQQEERKKKEELQRQKEIERQQRSRPFYHDRGGMER"
     gene            complement(2650..3063)
                     /locus_tag="LP245_002805"
     CDS             complement(2650..3063)
                     /locus_tag="LP245_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBL1520655.1"
                     /translation="MTRRKKRPNREHFYLRSDEMSEQKLNAENRKDSRQIKFRVSEDE
                     YQYLTAIADQTGMSVPQLCKSVALGMKYRAPNVDREGAIQIAKELRKYGGNLNQMARF
                     INMNKGQMPSSSDLALMNQQLSQIEKGVIDLWEQL"
     gene            complement(3562..3927)
                     /locus_tag="LP245_002806"
     CDS             complement(3562..3927)
                     /locus_tag="LP245_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520656.1"
                     /translation="MAKMDIEDLEKKLAEARHDLSVKIGTNMVEKQGFKSYSAYNTFM
                     RNASKALKSSAGSAPAPAAAKPVATSAEKLPSELKAEAVQFQKQLEKWMEDNWGNKLD
                     YKTFYPELLEFFQKLNSLE"
     gene            complement(3936..4097)
                     /locus_tag="LP245_002807"
     CDS             complement(3936..4097)
                     /locus_tag="LP245_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520657.1"
                     /translation="MTAKTVTIDVEQLEKLLERHSDAIIEYTGGLSEETINQFDLLLT
                     EIIELDSKE"
     gene            complement(4087..4236)
                     /locus_tag="LP245_002808"
     CDS             complement(4087..4236)
                     /locus_tag="LP245_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520658.1"
                     /translation="MKKRLRKKMAKKNSSLDQAMKELMNYAKGERDGFLIHSYDEKGE
                     QKNDG"
     gene            complement(4250..4999)
                     /locus_tag="LP245_002809"
     CDS             complement(4250..4999)
                     /locus_tag="LP245_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL1520659.1"
                     /translation="MGQPNKKADIALKDLLSRQDYLVVQGNDLAKAFGGLKSFEQRVL
                     DYCFSFVTKDSKLDDEYEVTALEIIKHFGLNTSGDSYRRIAEAFKKLNENTALYLRVE
                     RPDGTQGLRMTQLFSWIDFYADGLVRFKFSADSAPYVLDLKEKFYSFRLGELSRINGK
                     YALIMLKLWESYRRGKEKHTTITGDLEEWESWFLGKDKRLPAGQFFQKVITRAIEELS
                     DKMSVSFFVTTLKRGRKVVGYEITINDTSKE"
BASE COUNT         1374 a         1194 c          975 g         1732 t
ORIGIN      
        1 aaaaaaaaaa aaatcccgcc caaaccagtt gtctattttt ttccaacagg ttcgcgcatg
       61 aaataaactg cttctcacat catcgacaat ttatcccctt tacctcgttc aatcttacag
      121 ccacaaggca taaaggagtg atcgctacgc tctcacattt tgcttacagc agtcgcctgc
      181 gctccttcgt taaggtcaaa accgttgttc aaggagcggt tgggataggc gtaaaagctt
      241 gttgtagcaa gtttttagac tgatttagat taaatcgtta gtcttgttat acagcgcctt
      301 tacaggcggt cagggcaagc cctaacgacc caaaagcccc atctggtaga ccatcttttt
      361 tttgcaggga gtgaatgcta tattaatctt ggcactaaag ccaactaacg cttacacagg
      421 ttgggaggtg tattccgtat gtacgaaaaa tttctaacgt tggttgtcgc accgctattt
      481 gtcgggctag tcattgagct agtttctcat tggttggacg agaaagacga caactaaggc
      541 ttagtgcctt ccaactcaca cgcctagtcg cagggcgaaa aaaaagccag acaccgtcgc
      601 atggtgtctg gcttttgtgc attccgcact cgaaaaaatt ctaacgtttt cgcatggtta
      661 ttatagcatg gacgttggca aatctcaatt tcactgacta ttcagctcaa aataggattc
      721 tacatcgtca aatcgctttg tgtagcggtc tttcagctct ttatcgggca aagtagcgat
      781 cacgtcacga tttttttgta cccaatccgc cgtaataact tcgcttggat agtcttttgg
      841 gttaaaggtt ttcagctttt cttgactggc aattttcaat gcctgctcca gttggtccga
      901 aattttatca atttttttct gttttgcttc ggctttcgct tctagttgct ctattttgct
      961 gattttaggg cgtacagaca gcgcaacgtc cggacggtat gaagaaatgc cgaccgacac
     1021 aaaaagcgct agaaacgcaa aacagagggc aaaaacgaca cgtttcagct ttggttcctc
     1081 aaatttttct aagatcgagc gaaaaatgca gaataaacta tacgaaccga ccaaaataat
     1141 cacgacagga agaatatgcc accccatttt ttcaaagaac agtttcattt gcgttttaag
     1201 ccccctctcg ttcgattaca ggagctttag gactgaaaca ataagaatag cagtgccacc
     1261 gataaaaagc cccacagagg ctaatacgga cattaaattc gctattcgat tttgtttcag
     1321 ctcttcggca gtcgctcgat catcgttggc taaaaatttt tggacttgtg ggcgcacttg
     1381 ccggctcaat tcgtcagata cagatttgct gatattaccg tagctatcaa gcttttggtc
     1441 gatttcagcg gttctttttt gaacgtaggt ggcgtagcgg ttcatttcag ctttcagctc
     1501 gctcattttg ggaatatctt cgccacctcg caccttgata tagccttgtt ttacgctgtt
     1561 atcaaggctt ttcagcgttt caatgacttc ttgattttgt tgcttgattt ccgctagttc
     1621 ctgcttcact ttttgaagct cctgcttact tgcaaaatca tctaacggca tatcgtcact
     1681 acctttccat gccaccacga tcatgataga acgggcgaga acgttgttga cgctcgattt
     1741 ctttttgtcg ttgcagctcc tcttttttct tgcgttcttc ttgctgacga atatcattag
     1801 caagattttt caaaccgctg atagaaaagt catcattggt gactttaggc ttggtttcaa
     1861 gcggtttttc gacttctttt tcttgttttt gttgagaaaa ttcaagtgtt cgttcgatcg
     1921 cagggcgctc aaaatcagaa cctaattttc gtccgccgat tgtgaaatct ttgccctcat
     1981 catcgaccca tttgaagcca atccttttgc ctttattgta ctcataaacc tcgacagcat
     2041 aggcttcttg aagatttttt ttgaaagaat caaaatcggt actcatatct tgtgcgccca
     2101 ggatcatatg cttcattttt tctcgattac tcattttgcc ctcggcgtgc atttcaaaat
     2161 caacttgttt gaatttttct ttcggctgtt caatgccaaa actcaataaa accttatcgt
     2221 ttaggtcttg taggtggtag ccgacctcgg tatcagagtg aaatttttta ccggtttcag
     2281 tgtcgatact ggcgaaaaca atgtgattat gaatatagcc ggattctgaa tcggtatgag
     2341 tgcccatgta gatttcatga ttgggatagc tttttgcgat ttcatcaacg agtttagcac
     2401 cgatctcatg cgctttttgc acgtccgccg gattgttttt gtcaaacgaa ttatcaaacg
     2461 attgaaccca atgaaaggct tgaataccgc ctgttttggc gaaaatccgt ctagtcgctt
     2521 ctagctgagt ttgagccaat ttattctcag ctgacagttt gtgcgtataa atgcggtcac
     2581 gatcaagctt tccatgccga tttacatagc caatcagcgc agaagcccca cgtttaccgc
     2641 cttttaaagc taaagttgct cccataagtc aatcaccccc ttttcgattt gcgaaagttg
     2701 ctggttcatc aaggctaaat ctgaacttga aggcatttgc cccttattca tgttaataaa
     2761 gcgagccatc tgattgagat ttccgccata tttgcgcaac tctttggcaa tttgtatcgc
     2821 cccctcccga tcaacgttcg gcgctcgata cttcatgcca agtgccacgc tcttgcagag
     2881 ctgtggcaca ctcataccag tttgatccgc aatggcggtc aaatactggt actcgtcttc
     2941 gctcactcga aatttaattt gccgactatc ttttcgattt tcggcattca atttctgctc
     3001 gctcatctca tcactcctca aataaaaatg ctccctattc ggtcgctttt ttcttctcgt
     3061 cattcttcgt ggtcgatatt taaagctaca aaaacgctcc ctattcagtc gccttttttc
     3121 cgcaatgaaa tctccctcgg ttatgccact acaaaatgaa agttccctac tcggtcactt
     3181 ccctttttcc gctctataac cgaatgattt attaacctca tcatactccc tattcggtcg
     3241 cataacaagg ttaataaatc atataatacg caagcaccgc atttggtacc caaatacatc
     3301 gcttgtcgag gtggcgttgc cccctacgaa ctcccccaat cacgcaacaa aaagtagcct
     3361 gttcggctat ttttattacg tgatttcgcc tcagaaaaag tagtctgttc gactattttt
     3421 ctactggctc atgcggtcaa acttgcacgc aagttgacct tatttttttg tttgcccgct
     3481 gttcgcaggc aaacaaaaaa gcaagccaaa aatcggcttg ctcgttcttc aaaaattgat
     3541 cgcatggact agctcgttcc gctattccaa gctgttcaat ttttggaaga actctagcaa
     3601 ctcaggataa aatgttttgt aatccaactt gtttccccag ttgtcttcca tccatttttc
     3661 gagttgcttt tgaaattgca ccgcttcggc tttcagctcg ctaggcaatt tttcggcaga
     3721 agtggccacc ggctttgcag ctgctggcgc aggtgcagat ccggcggacg acttcaatgc
     3781 ctttgacgca ttccgcatga aagtattgta ggcggaatag ctcttgaacc cttgtttttc
     3841 aaccatattt gtaccgattt tgactgaaag atcatgccga gcttcagcta attttttttc
     3901 caaatcttcg atatccattt ttgccatgcg taaactcact ccttagaatc tagttcgata
     3961 atttccgtta gaagaagatc aaattggttg atcgtttctt ctgaaagtcc accggtgtat
     4021 tcaataatag cgtcactatg cctttctaac agcttttcaa gctgttcaac gtcaatcgta
     4081 actgtcttag ccgtcatttt tttgttctcc tttttcgtca taactatgaa tcaaaaagcc
     4141 gtcacgttcg ccttttgcat agttcattag ttctttcata gcttgatcta gcgaagaatt
     4201 tttctttgcc atctttttac gcagtctttt tttcaactaa atcactcctc tattctttgc
     4261 tggtgtcatt gatcgtgatt tcatatccaa cgacttttcg cccacgcttt aaggttgtga
     4321 cgaaaaatga aactgacatc ttatcagata attcttcaat agcacgagta attacttttt
     4381 gaaaaaattg acctgcagga aggcgtttgt ctttaccaag aaaccaagat tcccattctt
     4441 ccaaatcacc tgtaatcgtt gtgtgttttt cttttcctct acggtaggat tcccagagtt
     4501 ttaacattat gagagcatat ttcccattga tccgagataa ttcacctaaa cgaaagctat
     4561 aaaacttttc tttgagatca agaacgtatg gagctgaatc agcagaaaat ttgaatctta
     4621 ctaacccgtc agcataaaaa tcaatccaag aaaataattg cgtcattctg agaccttgag
     4681 taccatcggg gcgctcgaca cgaagataaa gcgcagtatt ttcattaagc tttttgaaag
     4741 cttcagctat tcgacggtaa gaatctccag aggtgttcaa cccaaaatgt ttgataattt
     4801 ctaatgcggt tacctcgtat tcgtcatcta gttttgaatc tttagttaca aagctaaaac
     4861 agtagtctaa aactcgttgc tcaaacgatt taagccctcc aaatgcctta gctaagtcgt
     4921 ttccttgcac tactaaataa tcttgacggc ttagtaagtc ttttaatgca atatcagctt
     4981 ttttatttgg ttgtcccaaa ctgaaaatcc tccttttgta ctttttttaa aataatacca
     5041 tttattcagt ttttttgcaa tatttgaatt ttcaacgtgg aaaatagtat ttttgacgtg
     5101 gaaaatagta tttttgacgt ggaaaatagt attttcaacg tggaaaatag tatttatagg
     5161 cgctacaaac gctggtataa agccattcct tttcccctaa agtattttaa agtatttaaa
     5221 agtaatctat aaagtattct ctttaagcgc gcgggtgaga aaaaaattta aattc
//
LOCUS       DAFEEZ010000119         4807 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000119
VERSION     DAFEEZ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.126"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(89..1174)
                     /gene="xerS"
                     /locus_tag="LP245_002810"
     CDS             complement(89..1174)
                     /gene="xerS"
                     /locus_tag="LP245_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBL1520660.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3250..3768)
                     /locus_tag="LP245_002811"
     CDS             complement(3250..3768)
                     /locus_tag="LP245_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBL1520661.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1579 a          786 c          730 g         1712 t
ORIGIN      
        1 taaaaatgat aatgaagctt gcctttaaag ttgggctttt atctaatttt agagacaggc
       61 ttcattatta tactattttt tactacattt acaaagcgtt caaagcatca attgtagctg
      121 cattgtctat atgagtatat aaagttgttg tatttgtact tgtatgtccc aattgttggg
      181 cagttaatac caatgaattt gtctgttgat agagtctagt agccaaagta tgacgtaatt
      241 tatgtggact gacttggact ctgaatcctt ttgaatattt tgctaccatc cgttcgattg
      301 caataccgga tatacgcttg gcttctcctt gataaattgc tagaaataaa gctttttcgt
      361 tttctgttac tttgtatcgt tctttccgaa tagctagata attagctaaa tattccattg
      421 caaatgctgc tatatttact gcgtctctct tatttccttt tctagttact accacattat
      481 tcttttctaa agataggtcc tctaaattaa tatttacaac ctcggagagt cttaatccag
      541 atcctaaaat caatgcattg atcgccaggt ctctttctac atctcgttga taatagatca
      601 aagctcgttt gctcaaagtt tttttatatt cattggcaat ataatctaga taattttgtg
      661 tatcttcgtc tagaaataat tttttctcga ttgcgtttgc acgggcagct aacgtagttt
      721 tatctgtgat agttgctact tgatccatag gattattttc taagtatggt tttcctaaag
      781 gattattgga acttttcgaa agatatttaa atagaacctt taatgctgtg atatttctat
      841 tgatagtaga agtagataga cctaagttat tattatcttt gagcttagtt tttgttgtct
      901 ctttttttac attttccttt gtgcgacgtt tcaaatgaga tttgtacaag tttagatcat
      961 aggcagttaa ctgtcttatc gaggtgattg aagtatcggg aacgatagac tcactcagaa
     1021 gccattcata aaagagctta taatttttta gatattctaa agtagttcga ggtgattgat
     1081 ctttatcctc acgatcttga acaaaatctt ttatataatc gggcatatga agtatgattg
     1141 tatctatttt ttgatatatt tctgtatttt tcatgttatt catcctttcg ataagtaggg
     1201 gagaggagta tctctataat tggactatac caattataga gtgttttgtc aattggtata
     1261 ctctgaaatt tattaattta tttcaaaaaa gcagataaat aggtatagat ttaataattt
     1321 aaaataaatg gtatacatga ataggaaagg aaacagaagg aggcaatctt aattttttaa
     1381 attgtctaaa ttatatagaa agaacaatct ttctatataa ttagacataa gagagactac
     1441 ggttgatttg atattaacaa gcgtatatga atgtatatac aaataaaaaa ggggagggag
     1501 aagttaaaga aaattcagag aagtggggca ctcagtagta ttaacaattt aaaaggaatt
     1561 tcttaaagaa aatgggttgc atcctggaga tacaattttt ttagataaag aaaaaattca
     1621 agcaacaatt caaaaaaatc ttaactgctg agattgatgt agcaatatct caatcatcaa
     1681 caaagtacga tcctgccttt caaaagctta ttgataaatg tttattcatt ataaaaataa
     1741 aagaaaaatt tatgtcagct tttttcatca aagtggtaat gataattcgt ctattaattg
     1801 tattttttag gaaatatggt ataattgttt taacgaaaag gtaattcatg atacaccaaa
     1861 aaccactagc tggcgggcta gtggttttct tttacgttct attcagatta acgggtaggc
     1921 ttactgtctt ttttggcaat aattttgcaa tcaagccatt tacagatgta atgcgcggat
     1981 acttctgcta agattgcaaa aaacatatcg aaaaggtaat tcataataca acctcctccc
     2041 cttgccataa taggccgggg tagcagacag cataaatatt ataccataac tgaaaatttc
     2101 attttagtac atttcaatat attgatgaac cagcacaata aaacatgcca tgactaacag
     2161 aaaaaaactt attaaaccag atataacttg taaacatcca actatataga aaacgtaaat
     2221 tttctatata gttggattaa gataacgact atttatttta tcatattttt actataccct
     2281 atacttttac ttggtatatt tatgaataat cgcaaattta cccctatact actagtttgt
     2341 aagttagatt aataaaaata ctaaagttat ttgttctttt attaaataca cctacaactt
     2401 ataaattgat ggtatttaga taacacgaaa gaataaaaat aacagctgat agtaaagttt
     2461 gttgacgatt gctactcaat cgaaagtgag ttagtgcgta tgaacttgct tctgaaaact
     2521 tatgaaatga aagacctttt acatcttgca gaaatcggta ctgggattaa actaagcaat
     2581 aaaaactaat gttcccctca ttctttgaac ttctactatt tgatttattt attctgataa
     2641 atgacgattt caccttcagg atcttcaaat cccgtataga atttatttaa gatctcttca
     2701 gtatcagtaa taggataggc gataggccac ataccctttg atggttagaa taaactgctc
     2761 aaaatctgta tcgtatgttg gctttagcat attaacaaag gctatctcca aattataaac
     2821 cataagcgtt gaatcgttct taacaatttc aattcttcct aacccaaagt cagaagatat
     2881 aattaccgga cttgccttac ccttcatgtg ggttgttgag attccatatt taaagggaat
     2941 tgtcggtact atcggcggtc tgaaaaacat cccaaaaata aaaaaatctt tcccctgcta
     3001 gtctcctaag tccctttgta gcggatatgg caccataatc tcattttatc gaagtgagtc
     3061 atggtttatc tgttggccaa ccaaaattga tacaatctaa cgatgcaccc tctacggcat
     3121 tctaggggag tgcacttgca ttcacccaat aaaaaccggc agttagcaaa gaacttatgt
     3181 agtcgtatgt tcttactgtt aacatacaag aggtctcctt tccacaattg cttagcagta
     3241 aacgggaatt tacaaagcta atctcttcca ttttcttatc tttgttctaa aagtcccaaa
     3301 tggagcaact gtatttacat gaataaattt atatacttcc catacagccg ttttggttgc
     3361 ctcgtctgcc cattttcttt tgtgtgcagt gaatagatct tcatcactca ttgaatcaat
     3421 catcatgtta atatcatcaa tattacgatt gagaatttcc tctaattctt tcaatggtag
     3481 atgtgcatag gtatttgtaa accacttata taactctcct aactgattcc atttaaattg
     3541 atcagaaggc gttttaacag ataatccatt tctttcatca ttttcccatt ttagaattaa
     3601 attcgtccaa ccaacttgat atgctaaatt ttcagcaggt gttctatcca cttcctcaac
     3661 tcttttatcc ttcaattctt caggaatagt ttcaaattct aaaatatatt tagtataagt
     3721 cctatttatt tcttttttta attcttcttt atttttatat gttctcatta tattacctcc
     3781 ataaattcct aattgtctcc tttaattcat ctataatttc atccacgata ttttaatccg
     3841 ttctacaatg catatctgat atgcattgac tgtctaactc atatgtgaat gatttataaa
     3901 atatcccaac gtctcatcta aagaaatgtt gatcgtcagc aaggagctaa aaaatacgaa
     3961 tatatttctt ttgtagtaaa atcggactgg tttgcatatc attttcttcg taaatatcaa
     4021 aatcatgtta actactatca attactaata aaaactacca ctttaagcgt taagaactgt
     4081 taagtttagt taagtgagga tagttcacaa aatccattgt taaacttcac gaaagtggta
     4141 aaactcaaaa tgctttatat aggattacag catcgctctt tcttcgattg cgcgttgggt
     4201 aaaaaatatt atgaagtaaa aattgacgat gacacgttcc ttacggctca tcagatgaaa
     4261 cagctacaaa aacgaaatga tcaactcgaa gaaaatttaa ttctaaaaaa gcgattgcca
     4321 tattcacgcc tcgctcgacg aactattaaa ggtcaagatt tacctgaaga tcatcctttt
     4381 taggaaattg aagcttttta tgttgcacaa tgcatttata atactacaat gatgttttca
     4441 ccagatattc ttctagggtg cggtgtaatg aaacagatac acttgcaaaa gaaaattcac
     4501 cgcgaattta ctaaaattat gaataattat gttaatcttc cgaaattttt ttccaaaatt
     4561 aagggatcaa gctggtgtta tagattgttt aaggttggca aaaaaataac ttctttttaa
     4621 acaattatag aaaaccgata ctctgttaag ttggttgaca cggtgtcgat ttttatgact
     4681 ttcttattct gaaacttcac taacggacag tacctaaaaa gtctatagta tggacgttta
     4741 cgagtactat tttatcaaaa atgctgctca tttcaactta tatgttttag tgaactaccc
     4801 ccactta
//
LOCUS       DAFEEZ010000120         4771 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000120
VERSION     DAFEEZ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.127"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..196)
                     /locus_tag="LP245_002812"
     rRNA            complement(<1..196)
                     /locus_tag="LP245_002812"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(882..2387)
                     /locus_tag="LP245_002813"
     CDS             complement(882..2387)
                     /locus_tag="LP245_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL1520662.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2384..3070)
                     /locus_tag="LP245_002814"
     CDS             complement(2384..3070)
                     /locus_tag="LP245_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL1520663.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(3263..4684)
                     /gene="gndA"
                     /locus_tag="LP245_002815"
     CDS             complement(3263..4684)
                     /gene="gndA"
                     /locus_tag="LP245_002815"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBL1520664.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1317 a          996 c          800 g         1658 t
ORIGIN      
        1 gattgttata cggtattagc acctgtttcc aagtgttatc cccttctgat gggcaggtta
       61 cccacgtgtt actcacccgt tcgccactcc tctttttccg gtggagcaag ctccggtgga
      121 aaaagaagcg ttcgacttgc atgtattagg cacgccgcca gcgttcgtcc tgagccagga
      181 tcaaactctc ataaaaagtt cgaacaatct tgcgattgtt aagctcaatt tgtttgctag
      241 catattgctt gcttgttaaa aatgtttgtt gtcttgaatt gaatcaagac gccctacaca
      301 tttggtttgt cttactttgt tcagttttca aaggtctaat ctttttgttt taacaactct
      361 ttaatcttat cagattcaga agagaatgtc aacaacttct ttgtttattt tttctaaacg
      421 tctttgccac tcattagcag cgacttgatt atcataccat ctttattgtt atttgtcaat
      481 aactttttcg aagttttttt cgataaaatc aagctttatt agctatctca tccaaacgac
      541 ttcgttatta taacatgaca tcaaaagtgc gtcaacacta ttttttataa tttttagtga
      601 caccttaaag gaatcattta gaacaaataa taatatagca atctctttat aaaattgcaa
      661 tagaaaattc cctattttta tttattattt ttaaacacga atattacagc attttattgt
      721 tttttcgttc atctaaaaga tacttacatt taattaacgg atgttattct atttaattgt
      781 tcgctagttt ttttataatg acatccctga atttctcact tgcttgtatt ttgtacctta
      841 ttctttgttg gatatataaa aaaacaagta aagcacatgc tttacttgtc ttctgccttt
      901 gcgataggaa taaagattct aaaaattgtc ccttgcccta ctacactttc tgctaagata
      961 cgtcctttat agttttcaac cagttgttta gcgatagaca accccagacc atttccaccc
     1021 ttcgttctag ctcttgcttt atccactcga taaaaacgat tgaagatctt attaaggtct
     1081 tctttgggta ttccttcgcc aaagtcctga atcgcgatct caaattcatt cagagtggaa
     1141 gaaatagaga tatggacttc ttttcgtgta gttgaatact ttactgcgtt atccaatatg
     1201 ataatgatta attgttcaaa gtgattacga taaatttgca gggtcacttc ttttgtcaaa
     1261 tcatcatcta aagtgatcac atagtctgga tataatatct tgaaattatt ataaacttga
     1321 taggtgactt cttttccttt agttgtttca ttcgcataat gaacatctac ttgttctgct
     1381 cttgataagt ctagcatctc ttgaactaag cttttcatac ggctgatttc ttgcatgctg
     1441 gcgcttaatg attcttctaa tatctcagga tcatctttcc cccaacgatt tagcagacta
     1501 agatgccctt caataattgc aacaggtgtc cttaactcat gagatacgtc ttccacgaat
     1561 tgctcttgtt gttcaatata caaacgcata cggtcaagca tctcattgaa tatttcagct
     1621 aaatctgcca attcatcatt tgtgtcgatt tcaggcatgt ggatatctga ttgcggatct
     1681 ttacgtatag tatccattgt atctctgagt accttgagtg gttttaagaa ataagaagat
     1741 aaaaagaaac ctaaaatact acttaagatc aaagaaacaa cttctaaaac aataagagtc
     1801 aataatagct tatttcgaat atcatagaaa gaagataatt catagaagct ttgcgcatag
     1861 ccgatctttt ctcttgtacc tttagaatat ataggctgga tagataaaaa gccagttttt
     1921 ccttctagtg taacgatcgt tggaacttta cgtgtagtct gaatcaggtt tcgactgttt
     1981 tcatgggttt taaaaatcaa gttctcgtcc aaatcataaa cataaagatc cattgatggc
     2041 tgccctagct cagctataaa ggaatcgatc ttcattaagt ttccttcgac cagtgaagta
     2101 tgatctacga cctcatctcc gtcatttgtc gctttcgtca gattacgata cgtatttact
     2161 aatgtcagtt cttcatccga gttagccaaa cgagaagcta cttctgaaat cgtacgctct
     2221 acattgtttc tttcttttgc cacaatcaga ttgatagatg atttataggt aatgacagcg
     2281 aaaattgtaa acacaacgaa tatgaagaaa gaactcgcaa aggcccactt gattgtcaag
     2341 gagggccctt tcagttctct tttttccgat tttttcggct ttatcacgag cgcatcacat
     2401 aacctgttcc gcgtacagtt tggatatagc tttcctcccc gggaacgtca attttgttgc
     2461 gaagataacg aatatatacg tccactacgt ttgtttcaac ttctgtttcg tatccccaca
     2521 ctttatttag taaaacgtca cgtgctaata ccacgttcac gttttccatt aaagtaagca
     2581 gcaactcgta ttctcttttt gttagttcaa ttacttcatt tccgcgacgt acgacacggt
     2641 tttctttttc gatagtcaaa tcgcgataag taatagtagt ttgtttagcc acatttttat
     2701 cgccttcaat atcgattcga cgcaacaatg cacgaagacg tgctaataat tcttcgatag
     2761 caaatggttt gacgatgtag tcatctgctc cgtggtcaag tccagataca cgatcgatca
     2821 cagaatctct tgcagtcatc ataatgattg gtgtattttt gacttggcgt acacgtctgc
     2881 agacttctaa accgttcaat tctgggagca tcagatccaa caatatggca tcccactcat
     2941 tatttaatgc cgcatctaaa ccagttcggc cgttgtagtg gacttctgcg ttataccctt
     3001 catgcttcaa ctctagctcg acaaatcgtg ccaagttctt ttcatcttca atgattagaa
     3061 tattgctcat ttattatttt atcctttcta ttctactggc tttttaaaaa ctctatcatt
     3121 ataccgataa tatgcttaaa aatctatagt cattttatca tggatagcaa ttttaaaaaa
     3181 gagctgaagt ctactcataa caatcgactt cagctctttc gtcctctttt tattttctca
     3241 tttcctaaca gccgaaagac tattattctt catggtacca tgagtaatgg aagattcctt
     3301 ctttgtcgac acgctcatag gtatgtgcgc caaagtaatc gcgttgggct tggattatat
     3361 ttgcaggcag acgttctgct ctgtatgaat cgaagtaagc gatggctgat gagaaagtcg
     3421 gtacaggtac gccagcttgg acagccaagg caacgacgtc tctgactgat tgctgatatt
     3481 ttttcgtgat ttcaacgaag taatcatcta gcaataaatt ttcgatctca ggatttttgt
     3541 cataggcatc cgtaattttt tgcaagaatc gagctcggat gatacatcca gcgcgccaga
     3601 tttttgcgat ttcaccaaat ggcaagtccc aatcaaattc ttttgaagcg acacgtaatt
     3661 gagcaaatcc ttgggcataa ctcatgattt tactgaaata caacgcttct cggatttttt
     3721 cgaccaattc ttttttgtct cccgtgaact caaaatcgtt cgtacgagac aaaatcttgc
     3781 ttgcttgtac gcgttcttct ttataagcag aaatatagcg ggcaaataca gattcagtga
     3841 tcaatggaag tggcacacct aagtcaagcg cgctttggct tgtccattta cctgttcctt
     3901 tattcccagc tgcatcaagg atcacatcta ctactggttt acctgttcct tcatcgtctt
     3961 tacgtgtcag aatgtcagca gtgatttcta tcaaatagct gtctaattcg ccttgattcc
     4021 attctttaaa gatatcagcc atttcttcta ctgaaaggtt taaaatattc ttcattaagt
     4081 cataagattc agcaatcagt tgcatatctc catactcaat accgttgtgt accattttca
     4141 cataatgtcc ggctccattt gggccaatat atgtgacaca tggtgctccg tcttctgctt
     4201 ttgcagaaat ttgctctaag attggtgcaa ctagcgcata ggcttctttt tgtccaccag
     4261 gcatgattga aggtcctttt aaagctcctt cttcaccacc ggaaacgcct gtaccgataa
     4321 agttgatgcc agagttggct aactcttcat tacgacgcat cgtatcttta aagaatgtat
     4381 ttcctccgtc aatcaaaata tcgcctttat caaggtgagg aagtaactct tggattgttg
     4441 catctgttgc cggtcctgct ttgaccatta gcaagatccg acgtggtttc tcgatagatt
     4501 ctacaaattc ttcgattgta tatgttgctt tgaaattttt atctgggtgt tcttctacta
     4561 cagcggttgt tttagcccct gtacgattga ataaagccac tgaatagccg cggctttcta
     4621 tgttcaaggc tagattttta cccataacgg ccataccgac aacgccgatt tgttgttttg
     4681 acatatgaac tcctcctaca tacgggattt ctccctaatc tcttacatta tagcttaaca
     4741 cggctacatt gcaaactaaa gaacaacata t
//
LOCUS       DAFEEZ010000121         4755 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000121
VERSION     DAFEEZ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.128"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(1..1149)
                     /gene="nagA"
                     /locus_tag="LP245_002816"
     CDS             complement(1..1149)
                     /gene="nagA"
                     /locus_tag="LP245_002816"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBL1520665.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1225..2061)
                     /locus_tag="LP245_002817"
     CDS             complement(1225..2061)
                     /locus_tag="LP245_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1520666.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2245..3462)
                     /locus_tag="LP245_002818"
     CDS             complement(2245..3462)
                     /locus_tag="LP245_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL1520667.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3611..3790)
                     /locus_tag="LP245_002819"
     CDS             complement(3611..3790)
                     /locus_tag="LP245_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520668.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3845..3928
                     /locus_tag="LP245_002820"
     tRNA            3845..3928
                     /locus_tag="LP245_002820"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3879..3881,aa:Leu,seq:gag)
     gene            complement(4168..4746)
                     /locus_tag="LP245_002821"
     CDS             complement(4168..4746)
                     /locus_tag="LP245_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520669.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         1438 a          995 c          770 g         1552 t
ORIGIN      
        1 ttatgcgtgg aaacgttcca cgccatctag ataagttgct tccaatgtca tatcagggtt
       61 caatacgata aagtctgcat cgcgtccttg agcgattttt ccacatgtat catcgatttt
      121 acagctgatt gctggaatca gactagccat catgactgct tgttctggtg ttgctaatcc
      181 ccagtctaca acatttttaa ttgcttcttt caatttcaat atacttccag ctaagttgcc
      241 agattctaga cgtgctgttc cttcttttac tactactgga aattcgccta aattgtaatt
      301 tccatcaggc atcccaccgg ccatcataca gtctgtaatt aatgcgacat gatcatgtcc
      361 tgctttttcc attaggattc ccgcagcatt tggatgtaca tgatggccat cacaaatcaa
      421 ttcagaaaag acatgttcta aagataataa cgcacccacc atacctggtt cgcgatgatt
      481 caatccacgc ataccattga aagcatggac aaatacactt gcgcctgctt caacagcttt
      541 ttgcgcttct tctagtgtag cattactgtg tcctagagaa acaactactc cttcttcagt
      601 cacttgtttg acaaactctt ctacaccttg acgttccggt gctaaagcaa tttttttgat
      661 taaaccacct gaagcttctt gccattcatg gaaagtatcc aaatcaggat ccccgaaata
      721 acttgggttt tgtgcccctt tgtgttcttc tgtgaagaaa ggaccttcaa aatagattcc
      781 tttgatttta gctcctggtg cttcctgata cattttgccg attgtctcag ctacatcttt
      841 taaacgttct ttgcttgacg tcaatgttgt tggtaaaaat gaagtcactc cacaagataa
      901 cagaccttca gacatcactt tgatgccttc tgcatcatta tccattacat catgattcat
      961 atagccgtga atatgtgtat ctaccaaacc aggagcaatc catttgccgc tttggtcaat
     1021 gatgttgact tctccctcag gtagttcttt ggtgtattca ccaaaaagtc catcggtaat
     1081 ttcaagatag cctgcatgtt tgacacctga cgctaaaaag aatttgtcag catagataaa
     1141 agttctcatt ctattctctc cctttgtttt tctacctcta aagtactctt atttagagaa
     1201 gaagtcaaga atggtctaca ccatttacaa attttttgaa atttgtttca cagcttgtgc
     1261 taagccttca tagaatgctg ctctttctgg ttcttcttta cgcttgtata ttaagctttt
     1321 aagcacaaat aaatcattga ggtaatagta gctattcttc tcttgagccc aatagattcc
     1381 ttgattcacc tgttctaacg cttcgtcgat ttcattttga tggaataaga aatttccata
     1441 attataaaaa atttgcgaaa attcactttt tgatcgttca tcagctgatt gatgcagcag
     1501 ttggatgctt cgactcaaat agtagcgtgc ttcagccgtt tttcctgcca caccatatat
     1561 ttttccgata caactaatca gttgtatttc tgtgtcagaa acatggattc tttctttttg
     1621 gctagagtag cttaatgctt ctttcaaata ataaagggac tgagagatat tttgacgcaa
     1681 cgtgaattcg caaacaccga gataataata atagcgttga aagtcagttg cttgatacag
     1741 attttcagaa atatcagaag attttagtac ttgttctaac ttccgataat cacgtttttg
     1801 gaaacaacta tccaacagtt caaataattt atcgtttgtc cgagtagttt ttcgagagag
     1861 attcatcaca tgatcaatcg ttacccctag ccgttgacaa atctgcatca tcaccaatac
     1921 attcggcagt tcctcattat tttcgatccg acttaataca ctttgtgaac aaatatcatg
     1981 cgaaagcatt ttttgcgtca ttttttgttc ttttcgaatc tctttaatga tcgttccaaa
     2041 ggactcgatt aacgtttcca taagtatcct ccccaaaata tgcgtattcg cattctattc
     2101 gtattttact ttaggaagtc gcaaacttca agaaaagact tgcaactaaa taatatactt
     2161 tagttattta agaaaactcc actagaaaga gagcctcagt gtgtttgtct gtggccctcc
     2221 tactgaaaaa tttggttttt aaaatcattt ttggcgatag gttgctagga attctctcat
     2281 tttcttagct gtttgtttca aatcatccat tttaggaaga taaacgattc gaaaatgatc
     2341 tggctggttc caattaaatc caccaccatg tacaagtaga atatgatgtt catgtaaaaa
     2401 gtccaaaacg aatttttcat catccaaaat attgaatcgc tttgtatcaa tttttgggaa
     2461 tatataaaaa gcagcttttg gttttacggc tgaaagacca ggaatatcat tgattgcatt
     2521 atagatatat tctctttgtt catagatcct tccgcctggc aggagcagct catcgacact
     2581 ttgataaccg cctagcgcgg tttggataat ttgctgagac aatacattgg aacacaaacg
     2641 catggaggac aacatattca gcccttctat atagcctttg acgtgtgact tatctccact
     2701 taggaccatc cagcctactc gaaatcctgc tacacgatga gatttggata gaccgttcag
     2761 cgtaacaacg aacaaatcag gcgctaatgt agcaatcgga atatgttcta gaccatccat
     2821 cactaagcga tcatagattt cgtcggaata aataatcagg ttattttgtc gagctacttc
     2881 aacgatttct tctaataatt cttttggata aagtgcccca gtaggattat taggattaat
     2941 gataacaata gcttttgtcc gactcgttat ttttgatttg atatcatcaa tatcaggata
     3001 ccattctgcc tcttcatcgc aaatataatg aacaggtgtg cctccagcta atgcaataga
     3061 agccgtccac aacggatagt ccggcattgg aaccagtact tcatctccat tgtccagcaa
     3121 cccctgcata cacatcgtga tcaattcgct cactccgttg ccggtgtaga tatcattgat
     3181 cgtcacattc ggaaaatgtt tcagttggca atattgctca attgcttttc tagcagaaaa
     3241 gatccccttg gaatctgagt agccttctga gtcacgggca ttcatgatca aatcacgaat
     3301 gacttcgttt ggtgcttcaa atccaaaagg tgcgggattt cccgtgttca attttaaaat
     3361 actaatgccc tcttcttgca tccgctccgc ttcttctaga acgggaccgc gaacatcgta
     3421 actgacacct tctaatttgt tggatttttc aaattctctc atcacttagc caatccctca
     3481 tttcaaaaag ttagaacttt ccaaattttt tgttatttac tatttcaata tcatactcca
     3541 tcctagaaaa ttttgccact tatttaggaa aaacgtaagt attaaaaaaa cacaaacaag
     3601 cgttgagaac ttaattgtca tgatagtcat tccatagatt cgctgcccaa tccattgcaa
     3661 ttccacaaat gattcctagc ataaaaccaa gcaaaaaacg tccgaatgca agtccaatca
     3721 atacacctaa gatcattccc agtcctgaaa attctccgtc atatttctcc atcttaataa
     3781 gtcctcccat ttttgagctt gacaactatg taaaacctcg ctatcattag tgtgttatta
     3841 ttacgcagat gtgttggaat tggcagacaa gcatgattga gggtcatgtg agcgttagct
     3901 cgtgtgggtt cgagtcccat catctgcact acaactcgtg aagttaattt tgcttcacga
     3961 gtttttttgt ttgaacgttt ctttatgcca ttatatacat atcactgtat cctttacaaa
     4021 aagaacgtac aatcatgtaa acagcctgag gtgagtatat gaaggtcgga aacaagctac
     4081 tcgtagaaac ttgcaagtgt taaaacaatt aatcgaaaaa cgagtaaaat ccctcaccta
     4141 atactaaagc gagggatttt ttgtatatta tctgtttatc accgttatta taaaggtaca
     4201 aataccaagc acggttaatc caaattgcat aaattcattt ttttgtacac tcatgctttt
     4261 cattagctct ttaactgcca ttagtactaa gatggcgata acaacataaa gtatatagta
     4321 cgtccgcatt ccggaagccc atactgtggg agaaaatccc ataattaacc ttgaacaaaa
     4381 tcccattatc atcaaaataa ctaaaaaaat agaagttttc ttattgtcaa aacttaaata
     4441 aattccaaca attaaacata gtaataatgc caagactact aaagtagcta tccaagtacc
     4501 tggataaaaa agtgacagtt tcgttcctaa ctctgtaaag agattattca ggttactact
     4561 actccaaatc attgcccttt tatttccatt gacgtaagta aagctttgac ccattgtatt
     4621 accaaaataa ataatcaggt ttaagaaaaa cggtaatgca gtcaatatac gcacataata
     4681 gttttgacat ttcctatatg ttagaaggaa aattaagaaa aatagcaata aaaataagat
     4741 attcatgtct aaaaa
//
LOCUS       DAFEEZ010000122         4621 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.130, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000122
VERSION     DAFEEZ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.130"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(15..962)
                     /locus_tag="LP245_002822"
     CDS             complement(15..962)
                     /locus_tag="LP245_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBL1520670.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(1140..1943)
                     /locus_tag="LP245_002823"
     CDS             complement(1140..1943)
                     /locus_tag="LP245_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBL1520671.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            2089..3003
                     /locus_tag="LP245_002824"
     CDS             2089..3003
                     /locus_tag="LP245_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL1520672.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            3051..3521
                     /locus_tag="LP245_002825"
     CDS             3051..3521
                     /locus_tag="LP245_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBL1520673.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            3606..4214
                     /locus_tag="LP245_002826"
     CDS             3606..4214
                     /locus_tag="LP245_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBL1520674.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            4348..4548
                     /locus_tag="LP245_002827"
     CDS             4348..4548
                     /locus_tag="LP245_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1520675.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         1512 a          716 c          912 g         1481 t
ORIGIN      
        1 attgttttca gctattaata tcctgcagac aattttactt gattggtttg aagctcatgg
       61 gtggcaaagt agcttttcag attggttaaa aaaatagcca ttaatttctt ttgaaaatca
      121 ggtgtcaaac ctgcaatgtg ggaagtaatc agtacattgt ccattttcca aagaggatga
      181 tcttgtggaa gaggctcttc ctcaaaaacg tctaatgctg caaaggaaag ttgctggtta
      241 tttaaagcct gcaccagatc ttgtgtctta acagaagcac cacggccaac attgatgaat
      301 acagattttg gatcaaagtg ttcaaacata tgctgatcaa agagcccagt tgtttcctcc
      361 gttagaggta agatattgac tacgaaatct acttcaggaa gaacttcctt tagttgattt
      421 aaagaaaaag tcttttccat tccttctgct ggatgaccgg atgtattgat tccatagcag
      481 ttcatgtcta atgctttgca tttttttgca atcatttttc caatatggcc agttccaatg
      541 attagtattt ttttcccttg gatagattgg taatggaccg atgaacctaa ccatttcatg
      601 tcactctgtg ccttttgtgc ttgaaaaaga ccacgagaat acccaaggat gattcctaag
      661 acatgctccg taatcgattc actgtggatg ccactaccat ttgaaagtaa aatatgtttc
      721 tttgaaaaag tctcaagggg tagctgatca acaccagctg agatagattg gacccatttc
      781 aaggtagaag aggctaatag tttttcttgg tagtctgagt tccagcccaa actgatctct
      841 acattttgta gatcctctgg ttgtaattct gttttaaaga tataaccagg cgctatagta
      901 tggatttctt cgataaattc atcacgaaat ggacgatctg cataaatgat tctttctgac
      961 atagttaatt tcccgccttt ctttactcta agtgtagcgc atacaagaag aactttgaag
     1021 cgccttgctt gttttttgag aaagaaatat ttttcaaata aaaaaggggc tgtgacaaaa
     1081 aaatgtcaca acctctaaaa gggtctattg aagtagaaat aacgagttgt ctttatttct
     1141 taattgatcg atatttttgc ccatcctttg acagcttgag caaaaataaa gattcctgca
     1201 aaagcaatga aggcgctagt gtcaaaagaa ggaagaaaga ccatcaagat tgttgcaatt
     1261 atagtaggca atgaaattga atagatcaat gtttttaaac aatcaagaaa agtagctttt
     1321 gttagtcgaa agcgtgcata gagaaaagca gcaatgttgg taaatagcaa agtgatcagc
     1381 agattcagaa aactaggata aatagaaaat ataaatgtca ggacttttat ccaaagtggt
     1441 atagatgctt cacttaaaaa agaacggagc tgcttacctg ttaagttttt taaagattca
     1501 ttggtgtagg gaagttctaa ttggttattg ttcaacaaag cagaagtcgt gcctgtatta
     1561 ggaagagcta tgataagttt gttttttaac atcccgacac taacaaaatt ccccatcaaa
     1621 tcagtagaga tgtcctgttc tgttcgtttt ccctctggat caaatgtgaa gataatggag
     1681 tttgtttggt aaatgaatcc ttctttttct tcggtttgaa gctgcccgtt ttggattgta
     1741 aaatcaggaa tgcgagtagc aatcttttgc ccatccaatt gaatgttgtt taagacttga
     1801 aaaacttgaa aagagattgg caaagccata attatactca aaactaaaag atagacaatg
     1861 gctttccaaa atgggacatt tctcgcctcc tttaggtctt tgaatcgtat aaaggaactg
     1921 ataattaatt gttttgttgt cataagtact cctcatctag tagtgtcatc acttgcaatt
     1981 ctagcgaagt atcaagtgaa atacaagtgc tttaaggaaa cagctgaatg attggtgaaa
     2041 tatcaaaaaa atgttattct tgtctaaaga ctatccaata taaataaaat ggaggaagga
     2101 atagtgccta cacagccaca gagatcatca aaaaaactat ttggagtagt ggttttgaat
     2161 gcggtgatca ctttatcaga atttattgga gggattatgt cagggagttt gtctcttgtt
     2221 tcagatgctt tccataacct tagtgataca ttggcaatta ttttttctta cggggcacaa
     2281 aaaatggccc gaaaagaagc aaataaaaaa cgtacgtatg gctaccagcg tttagaaata
     2341 ttgagtgctt tcatcaactc attcatattg atcatattat ccttgttttt aaccgttgaa
     2401 gcattcaagc ggttcacttc accagaaaag ataaatagtc atttgatgct aacagtagca
     2461 gttattggat tgctcgcgaa tttgttctca gtattattat tacgacaaga agcagatgaa
     2521 agtttgaata taaaatctag ttatttgcat ttgttaagtg atacactgtc ttcggtaagt
     2581 gtgattatcg gagcaatttt gatccgtttt ttcgatatct actggatcga tccagttatt
     2641 acactgatca tttcgatata tatattgata gaagcgataa tggtgatcaa aaaagctgcc
     2701 gctattttga tacaaagtgc acctgctatc gactatgaaa aaatggaaca agaaattgaa
     2761 gcaatcgatg gggtaaagga tgttcatcat gtccatattt ggcagtatag cgaaaagata
     2821 attattttcg acggacatat tgattttgaa gatcagctac taagcgagat tgaaaagata
     2881 tatcctcgta taatttcttt attaaaatta aaatatggta ttacacatgt gacgatccaa
     2941 gcagagacaa aggcaaagga tcaaaaaaaa ttaatttttt taaataaaga tgaaagttat
     3001 tgaaatatag agtatgataa ataagaattt ttaataaggt aggttggctc atgaagcagt
     3061 atcgacagtt aaaaggatat ttagaagcaa aaggatattg ggagatacta gtctatctct
     3121 tttttggtgg tttggctacg attgtaaatt ttgttagttt tgctctcgca cgccaatatt
     3181 ttgatttaag tatggcctta tccaattcta tttcgtggtt ttgttctgta ttgtttgctt
     3241 ttgtaacgaa caaactttgg gtattccatt caaaatcacc gaattttaca catgcactta
     3301 ttgaatgcgg taagttcttc ttctaccgta tcctttctta cggattggac atgggggcaa
     3361 tggtattgtt gatcaatgtt atgaacagca atgagtatgt ggcgaaaatc atcactcaaa
     3421 ttattgttat ccttgcgaac tatattttca gcaagttgtt tatttttaaa gaaactgagg
     3481 tttttgaaga agaagtaggt caaagtgaaa aagacgacta ggcataacaa ttgaagaatt
     3541 tccttctctt tgttactctt tgtaatgtag acattattaa gaaaacattg aggaggaatt
     3601 tttttatgac ttacacatta ccagatctac cttatgcata tgacgcattg gaaccttata
     3661 ttgacgaaga aacgatgcat ctgcatcatg ataagcatca caatacttat gtgacgaatt
     3721 taaattcagc aattgagaaa tacccagaat taggcgaaaa aacaatagaa gaattattat
     3781 ctgatatgga cgctattcca acagatatca agacagctgt acgtaacaat ggtggcggac
     3841 atgctaacca ttcatttttc tgggaaatca tggcaccaaa tgctggtggc gaacctacag
     3901 gagaaataaa agaagcgatt aatgaagctt ttggtgattt ttcttctttt aaagaagaat
     3961 tcaaaaaagc agccgctgga cgatttggtt ctggatgggc ttggcttgta atggaaaatg
     4021 gaaaattagc tattacctct actgcaaatc aagattctcc attgatggaa ggaaagacac
     4081 caattctagg tttggacgtt tgggaacatg cttattattt gaaatataaa aatgtccgac
     4141 cagattatat tgcagcattc tggaatgtta ttaattggga tgaagtaaac aaacgtttcg
     4201 aagcagcaaa ataaccattt cctccgtcat atcagtctta aaaataattt ggaaaataaa
     4261 agagcgaaag cttgctagcg ttttctaaat tgggtataat gttcttgcaa ggttacttgc
     4321 aagaactttt ttggaggata tacatttatg gaacacggaa cggttaaatg gttcaacaat
     4381 gaaaaaggat ttgggtttat tacagtagac ggcggagatg acgtatttgt tcatttctca
     4441 gcaattcaag gagacggctt caagagccta gaagaaggtc aagaagtaga attcacgatt
     4501 gttgaaggtg cacgcggacc tcaagctgct gaagtgacta aattataata atttgttgaa
     4561 taaagacacg acttcttaga gagtcgtgtc tttttgtcta tttatgaagt ttttagattt
     4621 t
//
LOCUS       DAFEEZ010000123         4580 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.131, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000123
VERSION     DAFEEZ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4580
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.131"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            338..901
                     /locus_tag="LP245_002828"
     CDS             338..901
                     /locus_tag="LP245_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1520676.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1180..1467)
                     /locus_tag="LP245_002829"
     CDS             complement(1180..1467)
                     /locus_tag="LP245_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL1520677.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(1457..1786)
                     /locus_tag="LP245_002830"
     CDS             complement(1457..1786)
                     /locus_tag="LP245_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1520678.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2091..2420
                     /locus_tag="LP245_002831"
     CDS             2091..2420
                     /locus_tag="LP245_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1520679.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(2707..3192)
                     /gene="vanZ"
                     /locus_tag="LP245_002832"
     CDS             complement(2707..3192)
                     /gene="vanZ"
                     /locus_tag="LP245_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBL1520680.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3345..4256)
                     /locus_tag="LP245_002833"
     CDS             complement(3345..4256)
                     /locus_tag="LP245_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HBL1520681.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT         1498 a          790 c          703 g         1589 t
ORIGIN      
        1 taaaacgaat aaattttgta gttctaattc aaatattgca tgttatatct aatatgggag
       61 cattttataa ttttcattgt gataaactcg ttattaactt taggatacac tagttaggat
      121 taaattaggt atctagaaat ttacttaaga tttttttgtt tatttcgtat acacactcgt
      181 atcaaaaaca atcgattatg agacaaaatg aaatgacctc ttttattaaa taaaagaggt
      241 catattttgt atcataactt gttgcattaa ctatgtatct ataactccct tttatgatac
      301 aatcaagcca gaattaaagt acgaaaggaa gaaaagcatg agtggataca tttatggtta
      361 tgcccgagtg agtacacgtt cacaagaact aaatcgtcaa ttagacttac tcaatgaaca
      421 aaattgtaat gaaatcctaa ctgagaaaat gacgggaacc aaagcggttc gtccccaact
      481 aaatcgttta aaagataaaa ttcgtccggg agatacggta attgtagaaa gtttttctcg
      541 attgggtcgt agtacaaagg atttgattga ccttgttacc tattttgaag aacaccatgt
      601 taagctggtg agcttgaaag aaaacttcga taccagcacg cctcacggac gcttaatgat
      661 gactgtcttc caagcattta gtcagttcga acgtgattta attgttgaac gtaccaaaga
      721 aggtttgaaa agtgcacgtg cgagaggtcg taaaggtggc cgtccacgag tgaaccagaa
      781 agatgttgat cgagcagtaa aattgtataa aagtcaggtt tatagcgtaa aagaaattac
      841 ggaaatgact ggtattagca aggcaacact ctaccgctac ttaaaagaca atagggaata
      901 atctatttta atctttagga atctataata tttatgggag aattagagtg atttttttat
      961 tattactaaa aaacaatata aaataacgca ttttaagccc tctttgtgca taaggatgaa
     1021 gcttttaatt tgaaagaggc ttaaaatgcg ttttaatttt ttctattttt cataaatata
     1081 taggttagtg gtttaaaatt atagggtatt acaactctca gctgttaaaa attatctttt
     1141 aaagtgtcgt ctatcctctc aagttgaaac attgggttct tacctaatct tttttaattg
     1201 ttcataaaaa ttttcatgcg ttccacatag taagataggt atcactgcat tatctttaat
     1261 ttcatatgca acgcgatatg tcgtacctgc atacttgaat ccaatagccc aaattcctga
     1321 taaatcaccc gttttttgtt ctcccgaatg aggacgaact gctatctcat cataaattat
     1381 cgttaaaaat tgttctttta atgttttctc ttttaatttt tttagatact ttattacgtg
     1441 tttagaaggt agaatctcat aagccaattt ctgctgccaa ctcctctttt gtcatcggtt
     1501 tagaatttgc aacagtatct tcagcaatag atttaaatgc agaagttaac gcattttttc
     1561 tatttctaaa ttcttttaag atctcttgtt tgctataacc ttctgaaaga atatcagcca
     1621 aaatatcttc actaaaatca aaaaattctt ttttaggctc tacaaactca taaaggatac
     1681 cattctctac aagcttagct tctacttcaa caccattggg cacatcgaat tctttaggga
     1741 ccgttaacat aatagaattt ccttgttttc ttgtttttgt aatcatatta tttcctccat
     1801 tattttacat ttcgtaatta cttagtaatt acattgtacg ctatttttag tagaaataca
     1861 aaataataaa actcctttag aacaattttc aaaggagttt tatttgatta ggaaattatg
     1921 tagaataata atatgttttt aacttggaat caaaaacgca cttgcaagta agtttacttc
     1981 aatacatgaa attgcttata atagtgtatt ggaattaagg tagattgaca aaagagtgat
     2041 caaataggta tacttcattc aaataatcgt ttgaatgtga ggtgagatga atgaaaaaag
     2101 tttgccaagt gactgtcgta cataaagaaa aagtaaatgg aataaaaaat aaattggatc
     2161 aaaaagattt ttcaaactta cttgtgttag ggaaatgttt cagcgatttt tctagaatta
     2221 aaattttcta tgctttagaa acctataagg aaatgtgcgt ctgtgattta gcagaaatac
     2281 ttactgctag tgtcgctaca acgtcacacc atttacgttt tttaaaaaaa catggaatgg
     2341 caaaatcacg tcaagatgga aaagtagttt attactcttt agcgaatgaa gacatccttt
     2401 ccgctattcg tgttttttaa agttatcaga aaatctatct atgaaatctt agtttggggg
     2461 taccgtcagg aaaatgcgga tttacaacgt taaggaaatt tattaaagag accaattcct
     2521 cagcactaaa attgataatt gggctttctt tgttactata gtgttaggta agctttttac
     2581 tttatcaccg gttttcccct cacttcacac ctacgggcga gtttccccac atcccgtttt
     2641 ccatctaatc caattcattc aatatcttta tgtgtatgaa agatcagatt gcttgattta
     2701 gacatcttac acgtaattta ttcttaaatg ggtacggtaa acgagcaata atacgagcaa
     2761 aagtatacct acaaaaataa taactctgtc taattttttt tgattcatat gcttattgct
     2821 taaaccatat aatttcagtc caagaaagcc tccaacagta tttgtaatta catctgttat
     2881 gtctgtcgct ccaatagcga agataaattg aattatttca aaagtaagac ttaaaaccag
     2941 tacaaaagca aacttaggta aaaatccgat ttctttaaaa ttgacattca aaagcaagcc
     3001 aaatggaata aagattataa cattatctat catctctctg aaattcccag tagcagtaaa
     3061 tggagtcaag ttaagacttc tttgatgata attaaatact gataaaatat tgtattgtaa
     3121 tttgaataac actaaccaga ttagtgtcac taaatataaa gctagcaatc ctctagataa
     3181 tatttttccc aatataattt cctctaattc ttttgtttaa gttgtatcat tagtatagca
     3241 atgtcctagt taacgtgggt tttaaattaa aaagctaacg ttaccccaaa agtgctagta
     3301 caataatgct gttcattaat ttcgttggtt tcattccgcc atccttacct ccttgaatta
     3361 gtatgtgttg atccgggaaa cactgtcaca attacaccgt ctatattgtt tcctgatatc
     3421 tcataacgaa gattagtcgg cacatgaatg gtggtatttt tagtaacagg ataataaaag
     3481 atctcatatt tttccccatt tacactaaca gaaatggttt tttcttcttt taggtaatcc
     3541 atatattcct cgagaacgaa attcttttct ttcataatcg cactatgtgg taaaccaaca
     3601 tagcgaatat gccatggttc atattgaatt cctgttaact ctgttttgtc ctctggataa
     3661 cgtaaaatga acccgtattt ccaagcattt tcttctatcc actttccttc aggggctcgt
     3721 tccattttcg tcaagcttga tcctacatct agtgataaac ctgaattatg ctcactataa
     3781 cctgctggta aggcatactc agcccccatt tcttggtaaa gcacactttg ctcatcaaag
     3841 tctcgatagc cactattaat aataaaatga ctaacgccac cctttacagc atcattgacc
     3901 atctctgaaa atttttgtgc tatttctttt gacatataaa tattactatc aagcaacccg
     3961 tatccattta ttaattcgtc atgtttagat aaattcacga tatctgactt cacactttct
     4021 tggcgaacag gatatttact attgattaat agcagatttc cttgataaac ctgttcttct
     4081 gtaattgttt tctcttgggt attttcagaa gtcccactat tttctaaatg ttctttggga
     4141 ttttgatcat aattttgaaa ttcgactttt tcctgagaaa acagtgcttc attaacgtag
     4201 tcataaccta agtatattaa gaataacaat aacaataaaa aaaacaactt cttcattttc
     4261 agtctcctcc ttaactatat agttggaagt atgaaatatt tctagaatct tccccttaaa
     4321 cggcacaatc tcgtttgaga ttgtgccgtt ttgccccgta aattacagtc aattatttcg
     4381 ccctactgga tttactatta tcaccaatgt agatgaattt tcataagtga tacccatgct
     4441 gaatttaacg aggctgaact gcctgttgac aatgggcggt gtgaaatacc acccctctat
     4501 gcgatcagtc ttattatcag gctatcttgc cgcagcgcac gcagataatg accgcaatat
     4561 cgctctgcct tacatcttca
//
LOCUS       DAFEEZ010000124         4465 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000124
VERSION     DAFEEZ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4465
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.132"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            73..234
                     /locus_tag="LP245_002834"
     CDS             73..234
                     /locus_tag="LP245_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBL1520682.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            253..1530
                     /locus_tag="LP245_002835"
     CDS             253..1530
                     /locus_tag="LP245_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1520683.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1540..2196
                     /locus_tag="LP245_002836"
     CDS             1540..2196
                     /locus_tag="LP245_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1520684.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2196..3572
                     /locus_tag="LP245_002837"
     CDS             2196..3572
                     /locus_tag="LP245_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1520685.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(3858..>4465)
                     /locus_tag="LP245_002838"
     CDS             complement(3858..>4465)
                     /locus_tag="LP245_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1520686.1"
                     /translation="YREYKSNPKECVNCPLLNQCTKSKNHQRVITRHVWGDLMDEVEH
                     LRLTDLNKSIYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLVFAAMNLKKL
                     ATWLWKGKEPLFFCSKIRNEVDKKLFQARVTSLEQLLSTVCDVGDISFSIRNQLRFKR
                     SLPVSGNINVYFTKARFKRLIAITVSSIVMFLWLFRMGVIP"
BASE COUNT         1717 a          535 c          780 g         1433 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcagga taaggataag tgtattaatt gtggaaaatg taaaaaagtt
      121 tgccaaatga ataaagattc agttgagaat tgcaatcatc tggagtgtat cagatgtgga
      181 cgatgtaaaa atgcttgtcc agtggatgca attagttatg gagtaagaaa atagagagga
      241 gtagttagga aagtgataaa aaatgctata gcatatatta caagaaagaa aaatagaact
      301 ttaataattt ttatcatatt aactatagtt ctttcttgct tgtattcttg tttaacaata
      361 atgaaatcaa gcaatgaaat agaaaaggct ttatatgaaa gttctaattc ttcaatatca
      421 ataacaaaaa aagatggtaa atattttaat gttaatcaat ttaaagatat tgaaaaatta
      481 aaagaaattg aagaaaaaat aattcaatat gatggattag caaaattaaa agatgctaaa
      541 gtagttagcg gagaacaaag aataaataga gaagatttat ctgacgaatt taagaatgtt
      601 gtttcactcg aagctacaaa taatactaaa agaaatattt tatttagtag tggagtattt
      661 acaattaaag aaggtaaaaa tatagaagaa aatgataaga attcaattat tgttcatgaa
      721 gaatttgcta aacaaaacaa tctaaaatta ggtgatgaag ttgatcttga attactagat
      781 attgaaaaaa gtggaaaaat aaaaagtcat aaatttaaaa ttatagggat cttttctggt
      841 aaaaaacagg aaacatatac aggattatct tctgatttta gtgaaaatat ggtgtttgta
      901 gattattcaa caagccaaga gatattaaat aattcagaaa ataatgaaat tgcaaataaa
      961 attttaatgt attctggtag tgcagaatct acagacttag ccttaaacaa attgaaagag
     1021 cttaaaattg atgagtcaaa gtattttgtt gaaaaagatt ctaatgcgtt tgaagagtct
     1081 ttagagtcag tgagtggaat aaaatatata ataaaagtaa tgacttattc tattatgtta
     1141 ggtgggatgg ttgttctttc attaatcttg attctatggt taagggaaag aatttatgaa
     1201 ataggtatat tcttatctat tggaacatct aagatacaaa ttataatgca atttatattc
     1261 gagttaatat tcatatcgat accaagtata atatcttcct tatttttagg aaatgtatta
     1321 ctaaaagtaa ttgtagatgg attcattaac tcagaggatt caatgatttc cggtggaagt
     1381 ttaataaata atagtagttt tatgtcaaat ataacaacac ttggacaaag ttatttaata
     1441 ttaataagta ttattgtttt atcagttgta tttgcttctt cattaatgtt aatcaagaag
     1501 cctaaagaaa tcttatcaaa aataagttag gagaaaataa tggatatatt agaaataaag
     1561 aatgtagcat atagttatgc aaattctaaa gaaaaagttt tgtcaggagt aaatcaaaaa
     1621 tttgaacttg ggaagtttta tgcgatagta ggaaagtcag gaacaggaaa atctacactt
     1681 ctttccttac ttgctggact tgataaacct caaacaggaa aaatattgtt taagaatgaa
     1741 gatatacaaa ataaaggata tagtaatcat agaaaaaata atatatcttt agtatttcaa
     1801 aactataatt taatagatta tttatcacca attgaaaata ttagattagt aaataaatca
     1861 gcagatgaaa gtatcttgtt tgaactaggt ttagataaaa aacaaataaa aagaaatgtt
     1921 atgaaattat ctggtggaca gcaacaaaga gtagctattg ctagagcatt ggtatcagat
     1981 gctccaataa tactagctga tgagcctact ggtaatctag acagtgttac tgctggagaa
     2041 ataattaata tattaaagac attagctaaa gatagaaata aatgtgtaat agttgtaaca
     2101 catagtaagg aagtagcaga ttctgcggat atcattttag aactaagtgg taaaaagttg
     2161 aaaaaagtaa ataaaatgaa tttggaggtt gaataatgat aaaaaatgca tttgcttatg
     2221 taactagaaa aagtttaaaa tcattaatta tcatattagt tattttatct atgtcaactt
     2281 taagtctcat tagtttatct attaaagatg ctacggacag agcttcaaaa gaaacatttg
     2341 ctaatataac aaatagtttt tctatggaga taaatagaca agtaaatcca ggaacaccta
     2401 gaggtggggg aaatgtaaaa ggtgaagata ttaaaaagat atctcaaaca gatagtatag
     2461 actcctatgt aaaaagaata aacagtgttg cagatttagt tgattatgat attattgaaa
     2521 ctcaagagac tcttgcgaat caatcacctg aaagagcaaa gaattttaaa agaacagtta
     2581 tgttaactgg ggttaacgac tcaacaaaag aaacaaaatt tgtatcagaa gcatataaat
     2641 tagtagaagg aaagcattta gaaaatgaag ataaaaataa aatcttaatg cataaagatt
     2701 tagctgaaaa aaataacctt aaagttggag ataagataaa aataaaatct aatttatttg
     2761 atgctgataa tgagaaaggt gcagatgaaa cagtagaagt agaaattaaa ggtctattcg
     2821 atgggcataa tagcggtgta gtaagtgcag cacaagaact atacgaaaat acattaatca
     2881 ctgatattca tacagctgct aaagtttatg gtaataccga agatacagct gtataccaag
     2941 atgcaacatt ctttgtaaaa ggtgataaga atcttgatag tgtaataaaa gatcttggga
     3001 aattagatat aaattggaga gaatataatt tgattaaaag ttcatcaaat taccctgcat
     3061 tacaacaatc tatatcaggt atttactcaa tttcaaataa attatttttt ggctcattaa
     3121 tatttgcagg agttgtagtt tcattattat tattcttatg gatgaatgct agaaagaaag
     3181 aaatagcagt attactatca ttaggtatat caaaattaga aatttttggt caattcctaa
     3241 ttgagatggt atttatatca atccccgcat tcgttggttc ctatttctta gctcaatata
     3301 cagctgacaa gcttgggaat aatatattga ataaggttac tggtgatata gctaaacaaa
     3361 tagctaaaca atctgcatct agccaattag gtggtggggc agaagctgaa ggatttaaca
     3421 agacattatc aagtttagat atcaatgtat tacctaaatt catgatttat gtagttatat
     3481 ttatgagttt agtacttctt gtatcattga ttatttcttc attcaatata ttaagaagga
     3541 atccaaaaga attattaatt gacaataatt aaaattttcg gtgcttttta gcaccaaaaa
     3601 tgagagtgta atataaaccg tgtaagtaac catcaatcct aggcgggtgg ttgcttcacg
     3661 gtttttattt ttctaaaata agatcaagag gtgattacac gatggctaga aagaaaagaa
     3721 atcctgatgc tgagaagtta gctgaatcca ttttgaatac ttatcaaccc gaatctgtag
     3781 aggatatgca agatgtttta aaagatgtgt ttggtccctt atttgaaaaa atgcttcaag
     3841 gagaattgaa taaccattta gggtatgacg cccattctaa agagccaaag aaacatgaca
     3901 atcgacgaaa cggttatggc aataagacgc ttaaaacgag ctttggtaaa gtaaacattg
     3961 atgttcccag agaccgggag gcttcttttg aacctgagtt gattcctaat agaaaacgag
     4021 atgtctccga catcgcagac tgtagacaaa agctgttcca aactcgtaac tcgagcttgg
     4081 aacagctttt tatctacttc gtttcgaatt tttgaacaaa aaaataaagg ctccttgcct
     4141 ttccatagcc aggtggctaa tttctttaaa ttcattgcag caaacactag catcgtatgc
     4201 gtcgcgactt tttccaagcc tcgatacttg gtccaacgca tcccatgctt ttcttttgca
     4261 tccgcaaata ttcgttcaat cgtttgtttc cgttttttgt aaattgattt attcagatct
     4321 gttaggcgaa gatgttccac ttcatccatc agatctcccc aaacatgtct cgtgatgact
     4381 cgttgatgat ttttactttt ggtacattgg tttagcagag gacagttcac acattctttt
     4441 ggattggatt tgtattctcg gtacc
//
LOCUS       DAFEEZ010000125         4401 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000125
VERSION     DAFEEZ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.133"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(98..1618)
                     /locus_tag="LP245_002839"
     CDS             complement(98..1618)
                     /locus_tag="LP245_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBL1520687.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(1861..2046)
                     /locus_tag="LP245_002840"
     CDS             complement(1861..2046)
                     /locus_tag="LP245_002840"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBL1520688.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(2030..2212)
                     /locus_tag="LP245_002841"
     CDS             complement(2030..2212)
                     /locus_tag="LP245_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520689.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            2453..2671
                     /locus_tag="LP245_002842"
                     /pseudo
     CDS             2453..2671
                     /locus_tag="LP245_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            3166..3765
                     /locus_tag="LP245_002843"
     CDS             3166..3765
                     /locus_tag="LP245_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1520690.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            3829..>4401
                     /locus_tag="LP245_002844"
     CDS             3829..>4401
                     /locus_tag="LP245_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage abortive infection AbiH family
                     protein"
                     /protein_id="HBL1520691.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIGD"
BASE COUNT         1402 a          799 c          785 g         1415 t
ORIGIN      
        1 taattcagta gttttgagcg taagcgtgtc atagaatggt acctaaacac aaatagcccg
       61 atttgataca ctcaaatcag gttatttgtg gcttatatta tttacagatt tcttgtatct
      121 gctgattcca tggcaaataa gcgcgtagcg cttcaggtgt catcgaagac agattgggaa
      181 tctctgtaaa aagatgattt aaatatttgc ggatgtttaa cccattcgca acagctgtct
      241 ggataatact caatataatt ccatttgatc tagcgccttt taagctttta gaaaatagcc
      301 agttttttcg accgatcact aactctttga tggcacgctc tgctcggtta tttgaaagtt
      361 ccaagcgtcc atcaagcaac acaatctgaa gtccgtcttt atgattgact gcgtattgaa
      421 ccgcctttcc aagctgcgat tttggcaaat aagcaaaact ctcacaccaa tgaaaaaatt
      481 cagtcatcac aggctgcaac gtttccttcc tcgctacaaa cctttcttct gcgctaagct
      541 tattaaaggt ccgttcgatt cgaaacatct tgtcacagaa gtctaatcct attttggcat
      601 gactttttgg ggacggttgt ttacccaatg cttcaaaaaa ctttctgcga acatgcgccc
      661 aacaataaac attgtttacc ggcagctttc cataggccgc gtaaccatca gtatgcaaga
      721 aaccgctaaa tgattctaaa aaactttttg gctcatcaac ggaacgcgaa tttgcgtgct
      781 cgtagagcac aacttgtttt tcttcgcttt tacctgaagc atataaccag taaaaggtct
      841 tttctttatg agtattcaat acccgatagc ttgtctcatc cgcgtgtaag acctcctgat
      901 tgcttaattc ttgatgaagg caattgtaga ttggctctaa aaccatttca cttaccttga
      961 tatgccaatt agtgattttt ttacgatcaa gagggaaacc aagtgcatgc cattcttttt
     1021 cttgtcgata tgccggcacc tttttaacaa atttttccca aatactctgt gtcacaattg
     1081 aagaggaacc tagactatta ttgatcaacg gtttaggaac aggcgctttt ttgatttttg
     1141 tttctcctaa tgcttcacat tctctgcaat gataggcatg ttggtagatg acttgttttt
     1201 ctatatgggc aggaacatac aatggctctt ctctaagcct tgtcgcaccg atatcatgta
     1261 aagtatgacc acagtcttca cacaaacaat cggcaccttt taattcataa tgaataggaa
     1321 cttcaggcag accttctaat gaaagtgctt tgagtccctt gcgttttctg cgtttaaaag
     1381 aagataccgt aatgggttcc tggctttctt gtccagtgtg ctctggttca ttaaaagttg
     1441 agtcgtctaa taaatcgatt tgcccatcta cgggtggtgt ttcttttttt cgtccaaaca
     1501 agcgtcgatt catttcagca atttgttctc taagaagagt attttcctgt tgctggattt
     1561 caagcaactg tgttaattgc ttgatttgta caagaagttc agattccatt tttgtcattt
     1621 ttacaccacc attctagcga ttttcttaca tctattatac cattttatga caacgaaaaa
     1681 cagacaaaat ccttgattta acaaggtttt cgtctaatat atcgcacctt ttttcgtttc
     1741 ttttagcgta catttttctt cgattgaaag gccagtcagt aagacttctt ttctggaacg
     1801 cggccattga aggtacccac tttcaaatct tttgtacatt aatacaaatc cattttgatc
     1861 ctagtaaaga gccttgaagc gatctttctt cgtaccgcaa aataagaaaa gcgcttgatc
     1921 gtaaacatca aggtcatatt cttctataac gaaagctgct agtccatcaa ttccttttcg
     1981 aagatctgtt tttccacaaa cgataaaaat atgtttcaat gcagttgcat caatgagcat
     2041 tggcattcaa ctcttttaac aaggtataca aaagatattt atccattcca ttataaataa
     2101 atatttcctt atcttccgat ttgattctgc aagctagttt tggcttggtg tcaatttgcg
     2161 atttttgagc cgcacttgaa aattgaactg gtacaatatc ttttttattc attcgttttt
     2221 ctccttctat atttgatagt ttaattatag aagaaagata atcggcgtac gagatactat
     2281 cctatgacac gcttacattt aatttaatat tttgcctcaa attagccaca ctttttatag
     2341 aactaagagg aaaaatgaag ttttcttcct attaatatag ttgtttgaaa tcttaaatat
     2401 agcgttttac gatgtaatgg gaagtatggt gaataaatca actatgttcg tacgaagcat
     2461 ttactcaact aatttaatcg aatctttcaa taaacaaatc aagaaataca gccaccgcaa
     2521 ggaacagttc caaaatgaag agtcgatgga acgtttctta gtctcgtctt ttgatactta
     2581 caaccaaaaa ttcctaggtc gcagtcataa aggtttccaa caggccgaag gcgagctcga
     2641 acaaatgctg agtcaaccga tggagaatta gaaacaatct acagtaggga agaaccattg
     2701 acacaaaatt attgacgctc ccaactaaaa gtgtcaaaat aatgatgaaa tcatttagtt
     2761 cttataaatt agaaaagaga aaataaatat tccatatcta ctttattgga tccgtaacat
     2821 gactaaattc tgaatacttt ttaaagctta tcatttggta aaactgaata taagttaatt
     2881 atatagactg aaaattttga attttcagaa tagaataact taaaagtact gacaaaattt
     2941 tttaaagggg caatattaat gttctgagat aatcaaatcc taccgaaaat atcaaaaatc
     3001 caatgtgaca caatcagatt gtgtctcatt cgagggaatc acacaatccc acgtggctct
     3061 aggcagaatt gaatttttgc ttggggcttt ttccttatat tgattttgaa tgagacttat
     3121 tatatgttat aatgcaatta agtatcattg gagagggcga agaaaatgaa gacggtagaa
     3181 cctattcgag acaaaaaaaa gatcgatgcg atgaaggcaa tcttggcttc gggaaaatat
     3241 ggccaacgaa atttggttct tttttcgatt gggatcaaca ccgcctatcg catttctgat
     3301 ttgcgtcaat tgaagctggc cgacgtgctg gaaatttcac gcggtcgcgt ggtggtcaaa
     3361 gatcgattag cgatgaagga acaaaaaaca gctaaacata attcggtcta tatttccaac
     3421 aaattgcgaa aaacgatttt ggagtacgtt caacaggaat ttcctgatca actccttcag
     3481 caagattttg acggttattt gttccctagt cgaaaaggga cgaatgaacc gctcaaccgc
     3541 caaagtctgt ggcgaatcat tcatgatgct ggcacggcaa tcggattgaa agacattggc
     3601 ccacattcca tgcgaaaaac gttcggttac tttctctata aacaggggac caaaacagaa
     3661 atcattcagt ccttgttgaa ccattcttct cagcgcgaaa cattgcggta tattggtatt
     3721 acacaagaag acaaagatac agctgtaaaa agcttagatt tataatataa aagttaagtt
     3781 taaacatgga tagttttaaa ttagtagatt gagtgttggg aggaaagaat gagtacatta
     3841 tatattatag gaaacggttt tgatttaagt catggtttaa aaactagata cactgatttt
     3901 tcaaaatggg ttgaaaaaag tcatagtgaa atattcgata aaatagacac aatgataaat
     3961 gaaaataatg aggtgagaag tacagctgat gataagatag gttggtttaa ttttgaaagt
     4021 agtttgcatg agttaattca aagtccagtc tttgaagatt atgtagaaga gtctaaggat
     4081 tatctcatag gttatggaca tgaagattgg tcagattctg cccatcatga ttttcaaaat
     4141 atggtttatg attatgttgt ttctctagaa gaattacaac aacttttcaa ggaatggata
     4201 cgcaaagaaa tacagccgac aatagaacat aaaattccaa aataccaatt ttcgtccgat
     4261 gtactattct ttacattcaa ttatacagat gttttggaaa ttctatacaa gcaaccgaaa
     4321 gaaaacatat atcatattca tggcagttat gacgatataa taatcggcca ctccgagaat
     4381 tttgacaact ttataggaga t
//
LOCUS       DAFEEZ010000126         4375 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000126
VERSION     DAFEEZ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.134"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(731..1024)
                     /locus_tag="LP245_002845"
     CDS             complement(731..1024)
                     /locus_tag="LP245_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBL1520692.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(1427..2604)
                     /locus_tag="LP245_002846"
                     /pseudo
     CDS             complement(1427..2604)
                     /locus_tag="LP245_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(2708..3022)
                     /locus_tag="LP245_002847"
     CDS             complement(2708..3022)
                     /locus_tag="LP245_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1520693.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            3129..3344
                     /locus_tag="LP245_002848"
     CDS             3129..3344
                     /locus_tag="LP245_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520694.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(3644..3886)
                     /locus_tag="LP245_002849"
     CDS             complement(3644..3886)
                     /locus_tag="LP245_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1520695.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(3873..4301)
                     /locus_tag="LP245_002850"
     CDS             complement(3873..4301)
                     /locus_tag="LP245_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL1520696.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         1387 a          831 c          654 g         1503 t
ORIGIN      
        1 taaggttatt ttagtcttgt cctttaatac aaagatttta tttttaaata aaaaatactc
       61 tttttttacg attattgaaa aaaaaagata aaacttgatt aattgaagta ttgcttaaat
      121 ttggaagcta tgagggaaga ataaaagagt taggacggga ttatctacta tttttctttg
      181 ttttaaatat ttgttatctt tgaacataaa agagaaatgt gtcgactgca gtgttgtgtc
      241 cctcatcacg aataaacggt gttcaactag ctgatcttgt attcacttaa aaaatggtaa
      301 agtacgagtt gctattcccc attttcaatt ttctaacgct caggacaaaa tactgttttc
      361 acaacctcat tggaataaaa gcatatatat tgtttcaaga acgaaatctt gttatctttt
      421 taaagggcat ctgtccaaaa tctaatttta ggaggtacgt tttggtattt attcgtacaa
      481 ataaaagaga attatcttta ttcatgtaac gcatccaatt gattttttca tgtacgctcc
      541 tggaacgatt ttactgacga ttgcttattt aactgcgaat cgctcattag cttttatcat
      601 agctatccat attttgaata acgttcttgg ctttgtatta tagatacaga tgacaaaaaa
      661 agttcaagta tgcggtgtag aaccaatatc gcatacttga acttttttca atgagtataa
      721 attaaaactt ctaattttca attcccatca tctgatatgc ccgaccgtct gaacttcttt
      781 tgaaaaagcc aaatgtgatt agataacgtc tttgttcgac ataatcgcca ctagaaaata
      841 cgttcagcag tatcgaatta acctctgttt ctgtataagt cactccatgg tcaaagcgtt
      901 tcaagacttc tttcaatagg atgtatttct tttttgttga acttggtact tgttttactt
      961 ttccatcatt catgaatgtg tctaaaactt tcatcttttc ttgctccgta taagtataaa
     1021 ccatcttctt tctccttttg attctaagaa tactccattt atgttagaat attctggatt
     1081 ttttattaaa gcggttactc ttaagaaaga tattatcata gtgctctttt ttttactact
     1141 acttataggt agatttattc taatccatta ttctccccta ccaataatta aagaaaaaac
     1201 tggatcaggg tgttcaaatt acatgctaag aaaaaagaac ccttgaatac caagggttct
     1261 ttctcagtct gataacaatg attaacgacg gatttctttg atacttgtga aaagtcgtta
     1321 aagtattgat ataaaaggat ttttattacc tctgactaca tattgactaa tttgttaaaa
     1381 aatcgttttt caagaatcct gtaataccag tgctttcacc gtttttttaa ctctctaaag
     1441 aactaaaagc aatcagaggt tttacctttt catttgacgt taagtggcga taaattttcg
     1501 aagttgtttg gtcagtatgg cctaagcgat ctttcaagac ttcccagcta cagtgttccg
     1561 ctactaagct tgccattgta tgacgagcta aatgagtatg aaatggctta ttaattcctg
     1621 agcgattcac gcaccgtttg acgtgatcat ttacatactc tcgacgataa ggaacaccac
     1681 gtttactaga atcaagatac acaaacaaat atgtttcttc tataataaac ctgtaatgtt
     1741 gcctcatctc acccaaagcc ttaatcaact gttgtagctt ttccataact agaggagtta
     1801 ctagaactcg tctagcagaa ctaactgtct tagtagtttc aattcgaaaa tccttactct
     1861 tacctttaac tgccgtttgc ttatagaaca gaatttcatt tcttttgaaa tctatatctc
     1921 caggctgtag agcaagcgcc tcgctgactc ggcagccagt gtaaaataga acatggaaaa
     1981 gtacagacat cggtaattcc tcatgaacaa tgccataatt caaaaaagtt ctcaattcat
     2041 cgacagtaag aaacttgtcc tcaatattat ttatggcttc ttttaaatca gttaccgtta
     2101 actgatattt tggcattctc acagacttca ttggattttc acttatcaaa ttctttcttt
     2161 gacaatattt aaaaatcata tttagaactt gaataagtga ttgtaaacta tttttggcat
     2221 agccaacatt tgttccatta acgccacatt cctttaaggt aaaaagcaat tcttgaaggc
     2281 actctggtgt caaatcagac aactttttat caccaatcca tcgaacaata atttttaatt
     2341 gttcctctcg cttatcatag gttatttcct tttgttcatt taacgaacgg taatattgga
     2401 accattgctc acctacaaca ctaaacttgt cattgcttgc aacaattttt tcttaagcct
     2461 ttgttgtttc tccatttcca gataagcgag ttgcgcctca cgttttgaat taaagccacg
     2521 tcttgttgtt cgatatgctt gaaagtacca tgtgatccta ccagtagaac tgatttgctt
     2581 cttgaatcga tctgtttttt ccatttattg attcctccta ttttgaagga acccaacaag
     2641 cagaaaccct ttggaaatct ttctatctat gtcatcattg taccgcatct tagaaagaaa
     2701 atgtaactta taaagatcga agtagtcgca atttttctcg atagtcattc gaatcactct
     2761 ttctcatcca ttctaaaaca tcatcacgaa aatagtgtcc tcgaatcccg taccaacagg
     2821 gaggaaactc accaagtttt actaaacggt tcagtgtact atcacttatc tgaaatagtc
     2881 gctttaaatc agtatttgtt aataccagag gtaaatgact gactgcaagc aatttttccg
     2941 tgtaatcttc cagttttttt tgtaaaattg aatagaactc tatttccaga gaattaacat
     3001 ttgttttaac ttccaactcc atcacccttc tctctcaaaa tcaaaacgac caccacggta
     3061 ccccttaaaa ttgtaaaaaa acactccagt actccatcaa aacggactag aaaagaggaa
     3121 tttttaatat gaaacaagga attgcagaca taaaaataat taaagaaatt cttgaaaaat
     3181 ctacggctaa tgcaatagca ttcggaacag gaatcaactt gagtacagta aaaaaactta
     3241 aaagtggaga gagagctgaa gaaaaattaa atcttgccga tgctattaaa atcacagaat
     3301 ttggcatgaa aaatatgcca accaaaatcg aaatatggaa atagtagttt ttctgatcta
     3361 tcagctgttt tgccaaagca cataggaatc tcacctcccc ccagtaatgg cgggccgatt
     3421 tggttacgga agtatcatta tcgtagtcgc gattctcata ttaaaatttg tcgcttaaaa
     3481 gctaaccttg tcatggcgta actagagaat caaaatctac atgtactgat agatttgcta
     3541 ttcatttgtc aaagagcgct aggctatttt cagcctatgg aaatccttta ttttgacccg
     3601 ataaaaaact tccatagaat gaaaaggaaa gggaaaaaat actttaacga gttgtatcaa
     3661 attcaagtat cttctcaatc aattttgttt ccagttgtct acgcatatat tcatctacat
     3721 acataaccat tcctttttct tcttcataaa ctggtttcat ggctaaccgt gaaatataat
     3781 tttgatattt tgacagaacg atggacatgg caattgaatc accagaagct gcggctttga
     3841 ttgtcgttag tggtatgaat ggtatatatc gtttattttg cttcatattt gacacccaaa
     3901 tactttccta gctcttccaa agccatttgt cgttggtacc aaacactgcc gagacttttc
     3961 ccaataatat cgccaatttc acgatcatta agaccgatga agaaggacat aaaaatgatt
     4021 tcttgtcttt gactaggtaa tgctgcaatc gcatttgcca actcctcatt ggaaataaag
     4081 attttcatac caaggacaat aaaagtacca ctactattca aatttggttc caaataatag
     4141 aactctgtac ctaacccttt ttgttccaat atttccattg atatttgccg ttggcgaaat
     4201 ctagcgtact tcttttgaat atttaacgcc tcattgcaga ctactttctt acaaaaactg
     4261 tcaaacgtat gttgaatgtg ggtttcctct gagtcgccca taatattctc cccctcaaaa
     4321 aattcattca actcgtttta cttctatccc tttccattat tactacaatc tagga
//
LOCUS       DAFEEZ010000127         4247 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000127
VERSION     DAFEEZ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.135"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(80..1888)
                     /gene="pepF"
                     /locus_tag="LP245_002851"
     CDS             complement(80..1888)
                     /gene="pepF"
                     /locus_tag="LP245_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBL1520697.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2064..3062)
                     /locus_tag="LP245_002852"
     CDS             complement(2064..3062)
                     /locus_tag="LP245_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBL1520698.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3288..3941)
                     /locus_tag="LP245_002853"
     CDS             complement(3288..3941)
                     /locus_tag="LP245_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBL1520699.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT         1248 a          897 c          658 g         1444 t
ORIGIN      
        1 aaaaaatacg tcgactccct tacaagagag ccgacgtatt tttttcgttt ctattcgaga
       61 aaatcaaaaa tagaaagcct tataaacgat cgatcaattc ttctaattca tttagacgtt
      121 gttcaaacat cgacattgca tcttcaatat atgcagcctg tgtcatatca actcctgctt
      181 ttttcattac ttccacagga taatcgctgt tacctgcttt taggtaagcc aagtagttct
      241 ctagtgcctc tggttcctgg tttagtattt tcttcgccag tgctgaagca gcagaaaagc
      301 cagtcgagta ttggaaaaca tagtaattat aataaaaatg cggtatccgt gaccattcga
      361 atttaatttc tgggtcttct tcgactgctg gaccataata ttttgcattc aatttaccat
      421 aactatcact taggtattca ctagtcaatg gcacaccttt ttcatcttcc gtatgcatga
      481 aatgctcgaa ttcagcgaat tgtgtctggc ggaaaactgt tcctttaaac ccatccaagt
      541 aatggttgag tacataagcc cgtacacgag ggtctttttc tgtttccaat aaatactccg
      601 ttaggatatt ttcattcgtt gtcgaagcaa tttctgctaa aaagatggag tagtcgccgt
      661 acacataagg ctggttcgaa cgagtgaaat aactatgaac actatgtccc atttcgtgga
      721 caagcgtaaa tagctgatcc agcgtatcat gccaattcaa taaaatatat ggatttgtgt
      781 catagcttcc cgaagaataa gcaccgcttc gtttcccttt attttcgaca acatcgatcc
      841 aacgttcaga gaatgctttt tctacgatgg ccatgtattc ttcacccatt ggtttcagtg
      901 cttctaaagc tttttctttt gcttcttcgt acgtaaaggt aattggagct tcccctaaga
      961 ccggtgtata aagatcatac atgtgcagtt tttccacttc taataaacgt ttccgtaatt
     1021 ccatgtatcg atgtaacaaa ggcaaatgct tgtttaccac gtctaccaaa gtatcgtata
     1081 cactttcagg aatatgatta ttgctcaaag acgcttctct ggcagagctg taattacgga
     1141 ctttcgcttt aaaattatgt ccttttatat gtgtgcctaa agtagaagca aatgtatttc
     1201 taaattgttc gtaaacactg tacaacccct taaatgctgc ttcgcgcacc cttcgatccg
     1261 tgctttctag caactgacca tacacgccat gagataattg gactatttca ccattttctc
     1321 cttcaatcgt tggaaaaact agatctgcat tattcaaaac agcaaatgta tcacttgaag
     1381 catcaaagat ttcacctgct ccagcaagaa gagattcctg ctcagcagat aagacatggg
     1441 ctcgattatc tactatttgc tggatataat ggcgatagac ttccaatttt ggttcttctt
     1501 tgaaatattg ccaaatctgg tcatctgaca attgcaatat ttctggttca aaccaggaaa
     1561 cggcttcact aactttcgaa aacagactgc ttgctcttgc ataaagcgct tggtaatctg
     1621 tatttccagt gtcttgatcg tttttaaggt gcgcatatac ataaatgact tcagtttggc
     1681 gataaaccct caatacgaat tcaatcgcat ttaaaaattg agaagcgcct tgatcaagtg
     1741 ttcctttgtg tttttcagat tgttttaact cttctgataa ttccaaatat ttctcatcaa
     1801 actcttggtc gcttgaaaag atcttggtca agtcccaagt taaattttca ggcaattctt
     1861 ctcgttttgg caactgcttt acttccatga aatccactcc ttttcttccc ttagctctat
     1921 ctatcaaaat agatcatagt ctaacatcca catgtcacag catctaactt ttctactcat
     1981 tcatgtgtct gcttccatca attttagcat aactaaatct tgttttacat agaaaaccga
     2041 ttcctagcct atttttatac ttactatttt ttcaaagaag acaagtgtat gcattcgtta
     2101 aaaaactgct gatagaccat ctcttcatca atcataggaa aaagccattc ccttttatgt
     2161 tcttttattt ggcaaagcca tgagttgaaa tcaggaactt tctggttttc caaggcttct
     2221 tcgtacaaca ttcgataaag aaaaacctgt tcttgtaaat aaaagaaaaa ccgacttttt
     2281 tgatagatcc acgatgatag atgcaaaaga tgtttatgac gcaagtagca ttgttcttgt
     2341 atggatactg tattcttttg cttgtgaata agttggcgtg tcagccattt cttcccatct
     2401 tcactcactt tttctatttt tttcatttgg ttcattttaa tttcgttact agtgaatatt
     2461 tctttaaggt ccctactaga aaaagtccag cagctactgc aaaaggaaat atgccctgat
     2521 acagtctctg taatatgatg atacaaataa agcttttgtt tcttgagatc agctttccag
     2581 caatgcactc ctctttttct attatagtag cagcaacttt tttctatcaa tgagaattgc
     2641 gattgtccaa gaaaagaatt accaagtatc caccatactt ggtaactgtt attcaaataa
     2701 ttttgggttc tttcaataaa tctctggtga gacagtctag aacattggat ttctattgct
     2761 agattcgcca acaaaatatc cggcctttgc cgcaacctcg gcaaataggc ttccaaaaat
     2821 actggttcta ctgactgtcc cagccaatcc atgaagcatt cctttaactg taagtgctct
     2881 tttgattctc tttcactaaa gaccgaacag ttatctgatt tttgatgggc aaaatgagca
     2941 cattttttct ttcccttttt caaaatcact ctttttcgac agccacgaca ataatatttc
     3001 tttccttttt ctgcatgttt agcaaaacag cacttattat attcattcat tgcaagcagc
     3061 atttttctcc ctctgaactt atttacgtct aagaatttat ttacacgaaa aaagagggcg
     3121 tgaaaaagct attctgcatc aagtaataag aacagctaaa caaaaatagt tcccaatatt
     3181 tttcgtttgg ttgggcttgt taccgcagat gcaagctttt gaacacattt atacgaaaaa
     3241 aagactgcga cacaattttt gtcacagtct cttactataa tgctgattta tacaaaataa
     3301 aatttcgttc gctcgatagc attacgcgcc atcagacatt gtccatattc attcaatgtt
     3361 tctggtgtac gatcgctctt ttcagcaaac tccaaaattc gagcaatctg attctctaca
     3421 tccgcttggt tgagattttc catccagaag tgaacgacta ggtaatagcg ctcttcgaat
     3481 aaatacaaat cagtccaagc agactctagt tcgacatctg ttgcaagttg gatcacttgt
     3541 tcaaaatctt caaaagcaaa agttgcttgt ctttcctgtt cttctagggc gcttccagat
     3601 aattcttcct ccggatcgct gccaataatc tgctgacgaa gaaagtcact cacatcttct
     3661 gaatcaacag tagaatcttc tgattgagaa atttcttcat ccggaagatt tttactgata
     3721 aacagttcta atccgtctcc ttttggcaaa acttggaaag tgacagcttc gcttcctcgg
     3781 aactcctctt cgatatcaac ttcttccaaa atactataaa agaaattttc gatttctttg
     3841 tgattgccaa gtaaatccaa aaatgaaacg ccccgttcct ctaaatcttc atgaccaatt
     3901 agtacacgga tcgtattttc attaatatgt tccatttcca ttttgctaca cctcactttg
     3961 ccacaatgtt taatatagat tcattgtagc gaaatcagct taaatgtaaa gaaaaaaaat
     4021 ctcgctgtta agcgaattta ataaaaccag cggatttttc aacctttcaa gctatcttat
     4081 ttaactataa catttttggc agacgaatac tatatagccg acttttcagc taattttccc
     4141 tctctatttt tcgtgcaatc atcatcttct actacctttt tatacatcta atcaagaata
     4201 ctttttgtaa aaacaaaaaa acttggaaaa actatctttg taatagt
//
LOCUS       DAFEEZ010000128         4175 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000128
VERSION     DAFEEZ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4175
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.136"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            612..1424
                     /locus_tag="LP245_002854"
     CDS             612..1424
                     /locus_tag="LP245_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520700.1"
                     /translation="MILLAVSMSLLIYTHILSTFMSVIVIGFLFIGSLFSKRKERKEM
                     SNLISNMIKAVGWTILLTAYVWYPMLQQVLHQKINRPFRTKLQERALNISDSLIGAVN
                     NDLVTFTMGTIGVVSFILPLFFKKKFANKEKIINFCAVTTWFLSTNLFPWEFLQKTPI
                     QIIQFPWRILGFQVLFGSLILIIVFLKWKTSNKKSMCSLVGIVLLIFTVTVATEANYS
                     QKIQSYKGRLIMTKKDVTLYTTSRTGGLYDYAPLDALKYKDHLKKHEVKVYD"
     gene            3059..3613
                     /locus_tag="LP245_002855"
     CDS             3059..3613
                     /locus_tag="LP245_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1520701.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            3867..>4175
                     /locus_tag="LP245_002856"
     CDS             3867..>4175
                     /locus_tag="LP245_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520702.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     L"
BASE COUNT         1542 a          516 c          661 g         1456 t
ORIGIN      
        1 atggcctttt tacttttaca caattataag gactttatcg aaaaaaagca gttatttgtt
       61 aaaatcattg atattattaa taataagtat tttttgaaag gggaaatata aaaggttttt
      121 gaaaataaat aaaaaatagt attacttgtt ctattgctag ttattgctag tctttattct
      181 tttttgtttt ttagggatgt acaaaagatc tcaaccacag gagacattgc ttttcacttt
      241 tctagaataa aatgcttgtc ctcagtattt tctggtccaa taaattttac cacatttaat
      301 agctatggcg gaggcgtgaa tttttttatc catatctaac atctttccag ccgtaatatt
      361 ttactggaca acaaacaatt tgattctaag ttatatactt actatacgtt gggatactga
      421 atatctgtac aattctagtg agctatcaat atggacaaaa gaatagatgc agccttctta
      481 ttcagctgtt tgtatagctt ttatggattg atatatatta gcgtactgca atttcagaat
      541 caattgcgtt gacgattgta ccagttgtct tgtattacac atatactctt ctttatgaaa
      601 gaaaaaactg cgtgattctt ttagctgtca gtatgagttt gctcatctat acccatattc
      661 tctccacctt tatgagtgtg attgttattg gcttcttgtt tatcggctct cttttctcta
      721 agcggaaaga gagaaaagaa atgtcgaatc tgatatcaaa tatgataaaa gctgttggtt
      781 ggaccattct tttaacagct tacgtttggt atccgatgtt acaacaagtc ctacatcaaa
      841 aaattaatcg tccttttcgc acaaaacttc aagaaagggc attaaacatt tctgatagtt
      901 taatcggtgc agtaaataat gatttagtta catttacaat gggaacaatt ggtgtggttt
      961 catttattct tccacttttc tttaaaaaaa aatttgccaa taaagaaaag attattaatt
     1021 tttgtgcagt gaccacttgg ttcttatcaa cgaatctttt tccatgggaa tttttacaaa
     1081 aaacacctat tcaaatcatt cagtttcctt ggagaatctt gggttttcaa gtgctttttg
     1141 gttcattgat cttaattata gtgtttttaa agtggaaaac aagcaacaaa aaaagtatgt
     1201 gtagccttgt aggaatagtc cttcttattt ttacagtgac tgtagcaaca gaagcgaatt
     1261 attcgcagaa aattcaatcg tataaaggtc gtttaattat gaccaaaaaa gatgttacac
     1321 tttatacaac ctcgagaact ggaggtcttt atgactatgc accattagat gcattgaaat
     1381 ataaagatca tttaaagaaa catgaagtaa aagtctatga ttgatgggag aatgcatctc
     1441 ataaagcaca taattctaaa ataatctata cagtaggaga tgcgaatgag caaaatatca
     1501 cgttacctgt atttaattac tgggaacagt tatgaaagta aatgggaaaa agagcactat
     1561 agaaaatgac aatggtttag tgtctattaa aggtacggga aaaagaacta tagttgaggt
     1621 ttcatctacg tatccaacta cgatgattct atctttatta attagttcaa taacttttat
     1681 attcttattt acacgttatt taataagatg ctgcggttaa atgaaaatag attagataga
     1741 tattataaat atgttgattc tattttcata gcaatggaga aaatacatta gcaatatata
     1801 aaagaaggta tcaagagtca cggtgaattt attccgaaaa gtgaaaagaa caaatataaa
     1861 atttaataaa aatatagaac taaataggaa aacgtagacg taattttcta cgttttcctt
     1921 ttcatatata ttaaatatta cggaaattta tataaactaa tttagtgttt tgtttgtaat
     1981 tcctaatttt gctccacttt tagataattt ttaggtctat ttaactcatc agacattcta
     2041 tgctcatttt ctccaaattt gtttcaactc tttcgtactt aattttgcgt atttgaaaat
     2101 tcttctttta gagtactttt attacgatac tagtatgata tatatctata gcaaacagtt
     2161 aaaatcttcc taaaataagc gaatagcatt cctaaaacct ataaaatttt tagatgaagc
     2221 gacaagtgga caattaataa actacttgaa catgaaatta tggatcacct ttcaaattta
     2281 gaaaatggaa ttcttatact tattgcgcaa catttattga ttgcaaaatt atgtgacaaa
     2341 aagaactagt agaagaagga ataatggctt gataataaag tactacctat taaaggtagt
     2401 actttattta atttagtata aattaacata ctactatatt ttaagtttca tattatataa
     2461 attaataata tactaccatt ttttggtagt ataatttaaa ggtaataagt tattctttta
     2521 ttactatgtt tgggttttat agcaaggaaa gtttaataag agtttggacc tagcaaacaa
     2581 tattaatgag gtcattaaat cttattatct ttagtgatat aacgaaatat ctacacagac
     2641 aaaattatga tcttgcgtaa agttataaaa tattaataaa aatattttat taatgaaaag
     2701 cttggtagca cggttattca tatgctaatt tatttcactt tatagtaagg ggagttctta
     2761 gtatattgtc caaatttaaa tttcatataa tttaattatg taaattagct attctaagaa
     2821 cttctacgga taactgcccg tctaaaattt aattaagagc ttagaatctt catataagta
     2881 aggttaattt ttttgtacaa aatagtcgga atattctgag ttactgaaat gatataaaat
     2941 cataaactaa accccttgat tttcttcact tttaacagag tatatatata agttcatgat
     3001 tatggtaaaa tatatatata atcatgaact cagaatattt ttaagaaggg aaacaatagt
     3061 gagctataat gtacaaccgt taaggacaaa tgaagagata caagattttc agttttggct
     3121 aagaagaaca agtaatccag aaagagatag ttttttattt ttgtttggaa tcaataatgg
     3181 gttacgtatg tcagatatta taggattaaa agttggagac atacgaggta aaagtaagcc
     3241 tattattgtt gaacataaaa caggtaagcg aaaaccgatt tttatagata atttgagaga
     3301 agagatttta ttatatactg aaggtaaaga agaaaatgat tggttatttc caagtcggca
     3361 acaaggtcga catataacaa gggatcgtgt ctatcagata tatgcagata tagcagaaaa
     3421 attaggaaga gatgatatag gaacacatac attaagaaaa acttttgggt atcactacta
     3481 caagaaaact agagacattg ctaccttaat gtttattttt aatcatagct cgcaagcaat
     3541 tacaaaaagg tacattggta taactgaaga tgaaataggg gcatcgttac gtggttttaa
     3601 attgggaggc taattgagat attaggatat attttttgtg tataatgaaa acttagaagg
     3661 tgagattaat gaagataact gaattttcgg aagtatttaa aacgtttagt aacatttaca
     3721 atagaatacc agagatagaa caaaatgttg tagttgataa tgattattat atagagaatg
     3781 attttaataa accaagaaaa tatgacaacc tatacaattt tatacacaat agaacaacaa
     3841 taaataacaa cagtaacact cgagttttga ttaattcagc atattttcat attaaatatt
     3901 taaagaaata tgagtatgaa gaagttgtat tagattatgg gctaaataga cagtcatttt
     3961 taatttatgc aataaataac ggaaatttgc caagcaataa aaagaacata attattgaaa
     4021 catatgccta tctggagggg ggatctaaaa aactaattaa gtcatgtaat atagagtatc
     4081 aattatcagt aggagaaatt aaatgtgttt tcgaagaaga tttagaactt gacttaaaaa
     4141 aaatttttgc cagcattcat gattatatag gtttg
//
LOCUS       DAFEEZ010000129         4157 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.137, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000129
VERSION     DAFEEZ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.137"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            179..775
                     /locus_tag="LP245_002857"
     CDS             179..775
                     /locus_tag="LP245_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL1520703.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="LP245_002858"
     CDS             899..2698
                     /locus_tag="LP245_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBL1520704.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="LP245_002859"
     CDS             complement(2976..3188)
                     /locus_tag="LP245_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520705.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3650..3799
                     /locus_tag="LP245_002860"
     CDS             3650..3799
                     /locus_tag="LP245_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520706.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            complement(4052..>4157)
                     /locus_tag="LP245_002861"
     CDS             complement(4052..>4157)
                     /locus_tag="LP245_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1520707.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1228 a          707 c          729 g         1493 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctacaatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacaaaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca ttccaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtataa tatttaatat aatcttaatt gtcaaattaa gttagacaga tcatcaatac
     4081 ttacgtaact caaaaatact tccaaaggtg ttcgataatc cagtgatttt ctaggaatat
     4141 tatttcgttt agatgcg
//
LOCUS       DAFEEZ010000130         4053 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000130
VERSION     DAFEEZ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4053
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.138"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..1235)
                     /locus_tag="LP245_002862"
     CDS             complement(<1..1235)
                     /locus_tag="LP245_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBL1520708.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQK"
     gene            complement(1228..2820)
                     /locus_tag="LP245_002863"
     CDS             complement(1228..2820)
                     /locus_tag="LP245_002863"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBL1520709.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(3330..>4053)
                     /locus_tag="LP245_002864"
     CDS             complement(3330..>4053)
                     /locus_tag="LP245_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520710.1"
                     /translation="KKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNIIE
                     EIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAID
                     NVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPPT
                     WKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKKD
                     YSVVFKNGQVTDYNEVFKKVIE"
BASE COUNT         1183 a          793 c          610 g         1467 t
ORIGIN      
        1 atcttttgta agaagccttt tttcgtttcc ttcagcaaat ctaacttacg ttgatgaaga
       61 gcgatcgtgt cgtcgagttg tttgaagaaa gcgccgattt tttgttgttc ctctttattc
      121 ctagtaaaag gaaacttgat attagcgaaa ttctcataga ataagtattc tcgtacgctt
      181 ccttcagtgt tgcgcttgac ctctttgata aatgttggtg acttgataaa ctgaagtatg
      241 aactcattat ctaagtcctc gctcattttc acaactacat aaagagagct aacaatgacc
      301 gtcataccaa gattgttaaa tgcaattgat cctacgttta ctcttgctgg attataggcg
      361 aattcatttg gttcaacgaa tttataattt gttttttcta aatcatccaa cctactacca
      421 tcaaactgtt ctgtttgaga aattaaacct gctttattac ttaccgaata ggcagggaag
      481 tctaaatctt tcgtgttctt ttttccagtc ttcttactaa actctttgaa cttacgctgt
      541 tcccaatctt ccgtaaatcc aggaaaccga atttctggca cttttgctcc gtttttaggg
      601 aacatttttt gtaagaatcc ttttttcgtt tcctttaata aatctagctt acgttgttga
      661 agagcgatag tgtcgtccag ttgtttgaag aagttcccaa ttttcttttg ttcttctaat
      721 attggaaatt gtactatcca ttttttcact tctgacattg gtacgagatt tgtaattgct
      781 gaacctggat tagctcctgt gagttttctt tgcataaaat ctgcacgaat aaattgaata
      841 aaatattctg aatctgtgat ttctttattt attctaagtc taatcaaagc ctgattgaat
      901 acacccggtt ttatttgctt tggtactctt gaaattctcc caattgttcc agcgccactc
      961 atgataaaat cgcctggttc taatttaaat ttgattaatt cattatattt tttttcagta
     1021 attttatatc ttgtttcgta attatcataa atagcatttt gttgttcata gacaacaaaa
     1081 ttgctattag atacaaagaa ttctttcttt aaggcactcc caaatggtcc cctccttact
     1141 ccatcttttt tatcaagtaa gcattcaaac ttacgctgtt cccaagcttc cgtaaatcct
     1201 gggaaacgaa tttctggttg tatatcatta ctcatgtttg aacacctcca gcgcaccttg
     1261 taaccacgct tcattttcag gtgttgtttg cagggaagag atagcttcta aaagttcttt
     1321 ttctagcact tgctgttctt gtcgtatctt cttgatgtca tttccgacat gaaccatatc
     1381 aattggttct tcttcttcaa acgtatctac atagcgtgga atatttaagt tatagtcatt
     1441 ttctttgatt tcatcaaagt ttgccaaatg agcgtatttc tcgacatctt ttctttcagc
     1501 ataggtttcg aggatttttt gaatgttttc ttccgataat ttattctgat tttttccttt
     1561 gacaaattct cgactagcgt caatgaataa tacgtctcga gtttggcggt tctttttcaa
     1621 tacaatcacc gtcgttggaa tcgatgtccc gaagaacaag ttcgcaggca taccgatcac
     1681 agcataaata ctgccgtctt ctagtaattt ttgacgaatg accccttctg cagcgccacg
     1741 gaataaaact ccgtgtggca agacgatggc catagtccct gtttccttca aatgatagaa
     1801 accatgaaga agaaacgcaa aatctgcttt ggattttggc gctaattttc cataacgatt
     1861 aaaccgagaa tcgtctaaga aggtcgtatc tgctgaccaa ttagccgaat aaggtgggtt
     1921 cattactact gcatcaaatg tgtaaggttc atctgttggc caatccttat tcaacgtatc
     1981 cccattgcgg agattcattt cttcggcatc taccccatgt aaaatcaagt tcatttttgc
     2041 tagattgtat gtcgttgtat ttaattcttg cccatgatat ttaacgttat ctgggtgagt
     2101 taagtagtta cgcacattta acatcaatga acctgaaccc atggttggat caaaaacact
     2161 aaagaatcgt cgttcttttt gatccaacgt cacgatttgt gccatcatat cagaaaccat
     2221 atgaggcgtg taaaattctc cggctttctt ccctgcttct gaagcaaatt gactgatcag
     2281 aaattcataa gcatccccga tcacgtcccc atcgtgacct aaaacttcca cgtcattcaa
     2341 tttcttaatg acttcggtaa tcgtcacatt tcgttgttgc tcatctgttc ctagtttttt
     2401 tgattggaga tccacatcat caaataaccc attaaattga ttgtaggtag atgccaattg
     2461 cacaaaggct ttgtttagat cattcaattg gaacgttgct tgttttgctt gatccgctaa
     2521 gacgttgaaa agatactctg gcgaaatcgc ataccccaaa atatcaacga ttgttgcaat
     2581 cagatcttct tttgattctt catctgaaag taattcgcga tacaacatcg tttgtttgct
     2641 taccgtatca tattcctcta aggattcatc tgctaaaaga accacttgtt ccaacaaacg
     2701 gtcggataaa tatttataga aaatcagtcc caataaataa tttttatatt ctgacgcatc
     2761 cattttgcta cggagattat ctgccgcact aaataatttt tgatttaatt ctgcacccaa
     2821 aaagatacac tcctatctct tatttaaagt tgctatatac cctcttattt tagcatactc
     2881 ccttttagaa aaagcaaaaa aaaaaagaaa gaaacttatt cttgctaata aactacgcga
     2941 aaggagtcta acgttgtttg atataactta gactgatcgt taacttattt tttatatttc
     3001 tacatagtta tctttagaac catttcagat acatatgaaa caattacata tgattttttc
     3061 ataaaaaaac agtactgtct agtagtataa aatatacaaa tttcttaaaa attttttcac
     3121 taaaatcact acctgaaaca gtctaaaaca cttatatatc aacgtttaat gaaactatct
     3181 ccgtttcatt tcagatacaa ataaatatag tcgggctcca aatccgaaaa aaaatacccc
     3241 cagtagctta tcctaagcta ctggagatgt ataagtacgg tcatataaca acggggtagg
     3301 gtaaataaat gaaaaagatg gaagaatcat tattcaataa cttttttaaa tacttcgttg
     3361 taatcagtta cctgtccgtt cttaaatacc acagaataat cttttttccc attttcaagt
     3421 aaccgaagtg gaatatcttt accaactttc tctgtcactg cattactgat acctgttaga
     3481 ttagctaata aatctgataa agattgagca tctgtagaaa tctctgtatc agtatttatc
     3541 gtgattcctt tatcttcatt tacaagtttc caagtaggtg gtatagctgt gtatgtttct
     3601 acaaatgaat taagtttttc attaagtgac ttctctttta tatttccatc taaaaactct
     3661 gtatatatgg cttgagctat actaaaacaa agctggcctt gttctaataa ttttacatca
     3721 ttagttagta aagctgtgtt cacgttatca atcgcttcaa gaagagtatc tttggtgtcc
     3781 ctaacagctt taggtgtgcc ttctggaatt tccctacttg atacctcgtc cattttatct
     3841 tccataaacc ccttaaaatc atatctttct cccaaatcca tagaagtttt tgagaaagct
     3901 ttcatttctg agtctatttc ttcaataata tttaacatgt ctgatacata ttgtttaggc
     3961 tgattcgttt ttaatctata tgtggtaaat atctcaattc ctccaattat caataaaatt
     4021 gccaaacaaa tccataataa ttttttcttt ttc
//
LOCUS       DAFEEZ010000131         3878 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000131
VERSION     DAFEEZ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3878
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.139"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(718..3867)
                     /locus_tag="LP245_002865"
     CDS             complement(718..3867)
                     /locus_tag="LP245_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBL1520711.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1076 a          803 c          637 g         1362 t
ORIGIN      
        1 ggactaatac aggtagtcct cttttttgtt attttgatat tctaaatcat tttttattgg
       61 attattccct tgttcgatat agacccaaat tgatctatca ataattatca aactgagtca
      121 tatagagaca aaaatttcaa aaatgacctg ttaaatggtc atcgaatatc atttaaaatc
      181 aatacgacgg agtcagacac ggagtcaaaa caagcccgct gagagtaaaa aatatataca
      241 gtcccatagg taaagtgcca caggactgta tattttttta tttgagatta cctgaaatga
      301 ttccatttac tttttatctc attttttcct actagttagt atcaaatact ctcctatttt
      361 ctcaataaac tattttgggt tacatggtat ctgaaacagc taaaaccttg tcattacagc
      421 aaaaaatcac tttatctccg tttcatttca gatacatttc acttaagcgg attccaaaaa
      481 aacaaaagaa aaaggaaccc ctagttagcc tatgcttttt attggttcct ctcaaaacac
      541 ggtcatataa caacggggtg gggtaaatga atgaaaaagg tggaggaaac attattcaat
      601 agctgtctta aatacttcgt tataaaatgt gaacaaataa aagacatcta tccctatttt
      661 ctacacttcc actttactac catctttgaa tcgtacaatt ttcttaactc ttctcgttta
      721 cctcaattca ttttcaagtg gaatcagctc atcatctaac attttacgcc atgctcgctt
      781 catttcttgt gggtatttaa atggcttcgc ttctggatgg ttggctttat atccttcgta
      841 atccttactg ttgataattg ctttcatatt aggaattgga tcttcacctg gcatatattg
      901 cagattagaa gcatgtaatt ctttctcaga aacaaaccac tcattggaaa agacatgaat
      961 caaatcatca ctcgcttgtg taaaatagcg acgtttaatg acaaagatat cttcattact
     1021 atctaaagtc cccacatcaa acgcatttaa aatttgtcgg taaacttctt tgactccttc
     1081 tgttttattc aatttagcca aagctttttc aatttcttct cgtgcatctg aactattcgc
     1141 cgcataagtt cctagtaatt gatcaatata agtagaatca atatcataca acttcgtggt
     1201 attttcacta taaaattcga tcgtggaaaa atcttctccc tctttttctg gttcttcctc
     1261 tattaatgaa cccttcacgg tctcgtacac gccaatttgt tcttccaaaa gttgaatttg
     1321 attgttcaag gttgaagatt tcaccatgtc atcattgtaa tcgtcataag tcactaacga
     1381 ttcataagca cgattcaatt cttggaatgc tttgacgtac tcgatacgga tttcaagtgg
     1441 cgtatgttca tcaatggatt ccatggatga aacctctttt aacttaccat atgcttgctt
     1501 gaatcttttt ttggattcct gataacttgg ataaatcaaa cccgattctt cttttgcttc
     1561 tgaatacagt tttgtcgcat cctcgacatt cttctccatt gtggctggct ttcggaaagt
     1621 aacaattagt ccttttgttt tttctggata cgtacggttc gtacgtgaaa aagcttggat
     1681 caatcctgca tactctagat tacgatccac aaatagggtt tgaatcgtag gtgcgtcaaa
     1741 acctgtcaat agacgatcca ctacgatcac taaatcaatt tgtttcccaa attgtttgaa
     1801 ttccgctctt tttcgtgcca aacgattatt gatgtctccg ttataacgct caatgtctgc
     1861 taatgaccag gaagtatcat aatactgatt atattcctca ataatttttt gcatttcttc
     1921 ttgttggaca cttgaatctc ggctgttttc ttctaatgaa taggtaatag cgattcgtgg
     1981 aaaatcagga tcctccatcg ttcttccttc acgaatgggc tgattaggaa actcttttgt
     2041 taaccagtca ggttctttcg tcatttcttt gatcgctcga taatactttt tggccatgtc
     2101 aatggaactc gtggttaaga tcgcagactt cgttggacgg ccatttcgaa aatcaaattt
     2161 tgtataggca ttgtctggac ggaacatttt atgaatgact ttttggatat gttcatctgc
     2221 ttcaaaaaca gtagggtcca aataactttc ttttttgaca ggctccattt gatcaatcat
     2281 acgattgatc tgttccggtg aatactctgc atatgtttct acttctttta atttccgata
     2341 gattttattc tctaatgaag tcggctccac ggtgttttca tgctctactt gaaatcctaa
     2401 aaccgagcca tcttctaatg cattcttgat ggtataggta tgcaagacct ctccatactg
     2461 atcatgggtc gtacgtgcca attgcccttt ggcttgtttc cgattctcag ggaaaatcgg
     2521 tgtacctgta aagccaaacc aagtggattt cggaaacatt tttttgattt cttccatatt
     2581 ttcagcactt aacgctcgat gacactcatc tactacaaac acgatatgtt gccccattaa
     2641 tttttggaag cgattggttc cttttttctc ttcttgtttt tttgcatatt tcaacgccgc
     2701 atctagcttt tgacgggttg taataatcac aacatttgca ttggcatctg ccaacagagt
     2761 ttcacttaac tctttggcac ttcctgttcc cacgatcaag ctattcgctt tggcgttccc
     2821 ggaagaaatc ccagtattaa attccgaagc aaatttcgta aactctgtgg tggtttgatt
     2881 atctaaatct ttgcggtcca ctaacatgat cgtccgatcg atccccgatt ttcgtgctaa
     2941 aagcttagta gatacaaaac tagtcaacgt ttttcctgaa ccagtcgcat gccacacata
     3001 tcctgattga tgtttatttg cagcaataaa caaggcttga atcgcatgta cttgataagg
     3061 atgtaacacc atgaggattt tattgtcttg atcttcactg acaatcgtat aatccgcaat
     3121 caagcgatga gcatccggga tatttagcac ttgtttgcaa aactcatata agttttctac
     3181 ctttttatta tctttcgttc gccaactaaa taaaaactta ggatgcaaat cctttggtaa
     3241 ggcatttgca aaataccgag tggtttgttc attggaaacc acaaacaact gtaaggtcga
     3301 aaagatattg ttccgaaaca taccttcttc tgcatatttt ttgatttggt taaacgcctg
     3361 ataaaaacta tcttttgcgg ttacttgttt cagctcgatt tggacaatcg gtaatccatt
     3421 gatcagtaag gtgacgtcaa aacgtcgatc ccgtgcttct atgttacttc cacgttttgc
     3481 aatttgatgg accacttcat aggtagagat tcctccacca atgtcttgat tagaataaag
     3541 aatgagcgag acagaaccca gttgcggatc ttcccgttca atcgtgatcc gagccattcc
     3601 attttcacct tttaaccatt tcgcagcatc aaagggggtt ttcgttcgta gtaacaattc
     3661 tgttttgatc gtttcaaatt ctttatcggt caaaggaaaa tcattcagtt ctgcttgatt
     3721 atttgagatg attttttggc gtaaattgac ccaaagatct tcttctgatt ttagatcggg
     3781 acgatacgtc cactgattat gcccttcccc caatacacgg atcaactgtt cttcgacttc
     3841 cgcttcctca cggtgactaa ttttcattta tcttccct
//
LOCUS       DAFEEZ010000132         3810 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000132
VERSION     DAFEEZ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3810
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.140"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            97..2196
                     /locus_tag="LP245_002866"
     CDS             97..2196
                     /locus_tag="LP245_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBL1520712.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            2392..3255
                     /locus_tag="LP245_002867"
     CDS             2392..3255
                     /locus_tag="LP245_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL1520713.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            3360..>3810
                     /locus_tag="LP245_002868"
     CDS             3360..>3810
                     /locus_tag="LP245_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL1520714.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEK"
BASE COUNT         1522 a          636 c          772 g          880 t
ORIGIN      
        1 ttaagtaaat cctaaaaata agctattggc gtgacgtata gaatatgata gattaaatgg
       61 tagcgtaaac ctagtaaagg agccgatcgc taagtgatga aaaaatgtcc aaattgcgga
      121 tcgaaaaaaa tggagcagaa tactatctgt ccagactgcg gtcatcaaat aactgcagaa
      181 gatcagcaaa taaaagaatc aattgaagaa acaaatacag atgcagctat gcaggataaa
      241 tcaactgaag atgcagtctt tcctgataca gaattaaacg atccaatcga atggtcggaa
      301 ttgaaagatt tacctctaga atctgtaatg gaattattcg aaaaagcaga accagaagac
      361 gaagaaccac ctgctcacga tcaagtaact aatatagaga aaaatgaaca gaagaaagca
      421 actgttcatg agacttcgga agaatcagga aagaatcaag aagaaacgct tgaatcaaaa
      481 caaaaaagaa gagtagctga actgaaagaa atcgtcgata atgaggaaga aaattcgata
      541 ctatccgctt atatcaaagc acatcgtgaa gatacaaaag aagagcacgc gaaagagctg
      601 ctcaaaatga tcagtgaaaa aattgcacag gaaaacaaag tagagccaga aaaggaacaa
      661 gaaactgaaa aagactctga tagagaaaac gccacaggta aagaaacagt aaaaataaaa
      721 gacgtaaaaa cggatatcac agaaaaaact gaagtattta ctgaaaaaca attagaaaag
      781 gaaaaaacga ataaactgcc ggaagcagag aaaaaagaaa tactcgaaaa cacagacaaa
      841 aagtcaacag agcccgatga aataaatagt gaatccgatg ctgaaaatca atctgtaagc
      901 aaagagggta ctgatcttga agcaaaaata gaaaaagaag agaaccagcc taagctgttt
      961 gaagcagaag cgaaatcaat aacaatcgtg ccagatactg aaaaaacaca tcaagaatca
     1021 aacttagaaa aaacagatcc agataaagcg caaaagaaaa aatcaaaaaa agtaccttat
     1081 ctcgttttag cagcagtact tctactcggt ggaggaagct gggcttatta tgaccatcat
     1141 caaaaagtag aagccgaagt agcagcagaa gcaaaaagac agcaacaaat ggaagaactt
     1201 catgagaaac ttgctgcctt ttatacagat gatcaccatc aatttattcg tgcagatatg
     1261 attcatcaag atttatcaaa actaaaaaat gatttatcca gtcttaagaa tgaaaaagga
     1321 tattcagagt tagaaacaac ttaccaagat atccaatcta agatccgaga tatccaaaaa
     1381 gtgaatgagt ggttcatagc acctgccatc gtcgatgatc atctagcaga tgacatcaag
     1441 ttgaaagcag ataaagagat ccaagcaatc gaaacggata acacagattt tggaaaattg
     1501 attcaacaag cacaaacaga agctaaaaat caatatgctg aattgcaaac agctaaagaa
     1561 aaaacagcta tagtctttaa agacggaaaa gtagtggatt cagcaacacg cgaccaatac
     1621 aagacggcaa aagaagcagt agaaaaagtg aaaaatacag atctatctgc tcagttgaat
     1681 gaacaattga aacaagtaga taagatgctc actgataaag agaaaaaaga agaagaggaa
     1741 aagaaaaaag cagaagaagc gaaaaaagca gctgaagaac aagcaaaaca agccgctcaa
     1801 gcagcagctg cagctcaagc cgctcaacaa gctgcggtcg cacaagcagc acagcaagaa
     1861 gcggcatcct cgaccccttc ctcttcaaac tcagcgaatc agccaatcaa atctgccaga
     1921 gcaagtgata ttgccgatgc atctaatcca gcatggacgt gggcaccagg tgtccaaagc
     1981 aaagtgattg ctacatgtat ccaacgtgga tatatcgttg aaggaggtta cagattagaa
     2041 aaagccagaa tcgaaaatgg ggaaggctat tataatctat atgccacttc aacaaaatct
     2101 gcattgatga aaggcattgg agaaagtgct ttgccatttt acatcgtaac catcaactgt
     2161 aaaactggat ggttcggagg aaatgggagc aattaatttt aggcaaatga aagaggctgt
     2221 gagcctgccg tttaacaccg tttattcgaa aaaggggagt atgacacaac tgttgtcata
     2281 ctcctttttt cacctttcca aaccaaggct cagctattca agtagataac attatgttat
     2341 gatagcaaag aaatgtatta agaaaacctt tcactataga gggagaaaaa aatgaacgat
     2401 ttattagcaa ctatatttac aggtattatt attgatgaaa atgaaaaaaa ctactttgtc
     2461 caaaaaaacg gacaaacctt tggcttaagc aaatcagaag gtgaacacaa aatcggtgaa
     2521 gcagttgaag gattcggtta ccaaaatcaa aaacatgaaa atcggatcac tacacaaatt
     2581 cctaaaagcc gtatcggtca ttacgctttt ggaatcgtta ctgctacacg aaaagattta
     2641 ggtgcgtttg tcgatatcgg tcttccagat aaagactttg tcgtatctct tgatgaattg
     2701 ccgacaatga cagagctatg gcctaaaaaa ggggatcgct tgatgatttc ccttagagtt
     2761 gatgcaaaag accgtatttg gggcagttta gcagatgaaa aaatattcaa atctttaagc
     2821 aaatatggaa cagaagaaat gaaaaacaaa gatgtgatag gaacagcata ccgcttgaaa
     2881 ttaacaggta cgtacgtttt aacggaagat ttctatcttg ggtttatcca tccttctgaa
     2941 cgatataatg aacctcgtct aggcgagcag ataaaaggtc gagtgattgg tgtccgacca
     3001 gacggtgtac tgaatctttc attgaagcca agagcatatg aagctatatc agatgatgca
     3061 caaatgattt taaccatttt agaacgttct gcagatcagc aaatcaactt tacagataaa
     3121 tcggatccag aagaaatcat gaaagctttt ggtatcagca aaggagcatt taagcgcgca
     3181 ttaggtaatc ttttgaaaca aggattgatt acacaagaaa acggtgtgac aaaactagtc
     3241 aaaaaatcta attgagaatc ccttgcatgt ttttcttaac tagcttataa taattttaat
     3301 taacatagtg ttatatcttt ttttatttgt aattattata aattgttggg gttgagtaaa
     3361 tggtcatgaa tgctatttcg gcgatgaaaa aaacaaaaca gcagctacat gaagcggggt
     3421 ttaagctgac accgcaaaga gaagctactc tgcttgtgct tttggaaaat gagaaagagc
     3481 atttatctgc agaagaaatc ttctttttag tgaaaaaaaa gagtccggaa attggacttg
     3541 ctactgttta tcgaaccctt gaaatcttga cagaattgaa aattgtcgat aaagtaagtt
     3601 ttaatgatgg attagcccgt tatgatttga gaaaagaagg cgccaaacat ttccatcatc
     3661 atttactatg cttgaactgc ggcacgatcg aggaagtaga agaggatctt ttacttgaag
     3721 tggagcaagt agtagaagaa cgttatcatt ttttagtaaa agatcatcgg ctaacgttcc
     3781 atggaatctg tcaggaatgc tatgaaaaag
//
LOCUS       DAFEEZ010000133         3760 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.141, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000133
VERSION     DAFEEZ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.141"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="LP245_002869"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="LP245_002869"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBL1520715.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="LP245_002870"
     CDS             complement(2260..2511)
                     /locus_tag="LP245_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBL1520716.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="LP245_002871"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="LP245_002871"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBL1520717.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            complement(3459..>3760)
                     /locus_tag="LP245_002872"
     CDS             complement(3459..>3760)
                     /locus_tag="LP245_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1520718.1"
                     /translation="AYPFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLT
                     YEEGITNAMIYPYSNGKIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
BASE COUNT         1030 a          803 c          703 g         1224 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatggct ctttgtcaat aaggactgat gagttgtgca aaatcaaatc
     3421 tgagtcagaa tgaaccacat tctggctcag attttttgtt atcttacatt gattaattga
     3481 ttgatcaaaa agattctaat tctcatgttc tcaaatgatt taaatccgta ggatactcgt
     3541 ttcattgtct ttatgtgggt attcttcgct tctatttttc cattggaata aggatagatc
     3601 attgcgttgg tgatgccttc ttcataggtc agaaggtttt gaagcttttc ccgaaagctg
     3661 tcatctaacg tttcgggaag ttctgccaat aaggagaaaa ataagtcagg gtctttgtct
     3721 cgaaaggctt caactaattc atgaaaaaag ggatacgcct
//
LOCUS       DAFEEZ010000134         3294 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000134
VERSION     DAFEEZ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.142"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            39..590
                     /locus_tag="LP245_002873"
     CDS             39..590
                     /locus_tag="LP245_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HBL1520719.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
     gene            1266..1520
                     /locus_tag="LP245_002874"
                     /pseudo
     CDS             1266..1520
                     /locus_tag="LP245_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            1590..2102
                     /locus_tag="LP245_002875"
     CDS             1590..2102
                     /locus_tag="LP245_002875"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1520720.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLC
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            2099..3136
                     /locus_tag="LP245_002876"
     CDS             2099..3136
                     /locus_tag="LP245_002876"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL1520721.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
BASE COUNT         1214 a          555 c          654 g          871 t
ORIGIN      
        1 agagcgagca agacaggaac gagagaacaa acatactcat gaaaagacta gaggcttcga
       61 cctcgaactt taataataag ttagatgttt ttgaagaaaa gactaagcat gcaagattaa
      121 actttgaaac aactgcaaag cactatatta aacgacttga tgaagataat ttgaaattag
      181 attttcaaca agctattcaa gatgaattaa gcgatactaa agacgaaata cgtgaagtga
      241 cgaaacaagc gagagaagaa acaaaagagt ataaagaaat cttagaaagt aaaataaaag
      301 accataacaa agtggttgat aaatcgaata cagcgctaaa agtgatgaca aaaggcgtta
      361 caaatatatt ttttgtgcta attatttttg tacttgtaat gcttgtgaca ggtccgatag
      421 gtcatttctt tggtattgaa catttatata gctttattaa tggttttatt gatgaccacg
      481 aaagtgcatg gcgatatttg atgttgatac tttatgcagt accctatgta ttcttcgcta
      541 tcattctgtg gctcatagca ttgtttttta gagtatttaa tgacctttag gtagatttat
      601 atataaaaag ggctaaatac gcaaaatacc cccttaaaat gcaaaataaa tgcaaataag
      661 ggggtaactc cttatgaaaa aacaactaat agtattataa cacgttttta tgccgagaaa
      721 acttattggt tggaatgggc tatgtgttag ctaacttgtt agcgagttgg ttggacttga
      781 attgggatta atcccaagaa agtaccaact caacaacaca taaagccctg taggttccga
      841 ccaataagga aattggaata aagcaacgaa aggagttgag taaaatgagt gagaaaacga
      901 agaaaatcat tcgagtatca ttagcttttt cacaagtagt agtgcaatca ttgatagttt
      961 attatactta ccagcaatat aaattatcta aagagaatta agttttgatt atgtaataag
     1021 ttttggtact aaaaaagact tgatctaatt agaccaagtc ttttgttagt gttatattaa
     1081 taacaaaata aaaataagaa gtcgctcact ccccgaccaa agtttgtgag caaaataaac
     1141 agtcgatgtt tgtttcttaa ttgtatatct tgatattaaa cgatttaaga ttattcttca
     1201 agatatatat tcgcaaatgt aattggaaaa gcgacttctt aaacaaaatt aaggagtcgc
     1261 tttttatggc aaaaataacg aaaaatgagc aagaaaattt ggtggaaaat tacacaaaaa
     1321 aaccggcgta ctctaatagc cggttagacg cacatttcgt gtgcacttct aatccgaaat
     1381 tgagctttga cgctatgacg atagtcggaa accttaataa aaacagcgct aaaaagctat
     1441 ccgattttat gagtttagat ccacaaatta gactttggga tatacttcaa acaaaattta
     1501 aagctaaagc actacaagac cccctatgtt aggctagttg tcgtatagga taataagtta
     1561 taataaagac tatacggagg atgattacca tgacaaataa aaacaatgaa cgttactcta
     1621 ccgaactgaa agcgacagcc atcaagaaaa tgatgccacc cgaaaatagg gggattcgcc
     1681 aattaagtca aactttgggc attccagaag cgactctttg ttcttggcgt aaaaaagcta
     1741 gaattcaagg gaatactaca cccggaacga aaaaaaatgt cgaaaaatgg tcaagtgaag
     1801 ataaattttt aattgtgatg gaatcattct caatgaacca agtagaactt gcggaatatt
     1861 gccgaaagaa gggcttattt aaagaacaaa ttgaggcttg gaagaaaacg tgcttatctg
     1921 cgaatgaaca ggaagaaaat cgaacgagag aacttgcaac tgaactaaaa gaagagaaaa
     1981 aacaagcgcg tcaattagag aaagaattac gtcataagga aaaagcatta gcggaagccg
     2041 ctgctctctt attactaaga aaaaaagcac acgcgatttg gggggaccaa gaggaagaat
     2101 gatttcatct tcagatcgca aacaagctgt tgaacttatt caagaagcca atcgcaatgg
     2161 ggcccgtctc acctatgcct gtaatgagct gaatattagc gttcgaacct acgaacgatg
     2221 gacgcgtgaa ggtacgatag cgcatgatca acgccctttg gcgaaacgtc ctgtacccaa
     2281 aaataaactg acggatcaag aacgcgaaaa aataatagaa accgtttcaa aaaaagaatt
     2341 tatgaatttg ccacctagcc aaattgtacc aaaacttgcg gattgctcga tttatattgc
     2401 atcagagtct agcttctatc gtgtattgcg agaaaaaaat atgcaacatc accgtggccg
     2461 aagtcaagtt tcacaaaaac gcataccgcc aagtcacctt gcgacgaagc caaatgaagt
     2521 ttggacttgg gatattactt ggctaaaagg tccaataaaa ggactctttt accggttata
     2581 tctcatcatt gatttattta gccgtaaaat ggtaggctgg gagatttggg aatcagaaga
     2641 agctcgtcat gccgaaaaac ttattaaaca gacggtgctt aaggaacgta tccaaggaca
     2701 gccgttggtt ttacactccg ataatggcag ccctatgaaa gccgcgactt ttcaagtctt
     2761 actcgaaaaa ttaggaattc aaagttctta ttcaagacca cgagtgagta atgacaatcc
     2821 ttattcggaa gcggctttcc gaacgttaaa atatcgacca gaatatccca ataacggctt
     2881 taaaacaata gatgatgctc gaaaatggac gaaagagttt gtcgattggt ataacgattc
     2941 tcatttgcat agtgggattc aatttgtgtc tcctgcagcg tgtcatgaag gacgacatct
     3001 cgctatttta gagaaacgaa agcaggttta cgaggacgct aaaaagcgcc atcctgaacg
     3061 ctggtcaaaa ggtgttcgaa attggactcc acatcaatcg gtggcgttga atcctttaaa
     3121 agaaacagaa agttaacagg agcataatct ttcaagatta tcaaataacc ctcgtcaccc
     3181 aataggggaa aaagttattc ttcccctatt ggataacgag gccaaccgac catagggagg
     3241 ttctgctttt tgataggtgg aaaataaaaa tacgacaact atattgacaa acac
//
LOCUS       DAFEEZ010000135         3230 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000135
VERSION     DAFEEZ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.143"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            50..1438
                     /locus_tag="LP245_002877"
     CDS             50..1438
                     /locus_tag="LP245_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HBL1520722.1"
                     /translation="MYKERDDLNYTLIINKDGNYSWRPLVLLHPILYVDLVNCLTKED
                     HWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILNWWEYFEQKSLAQNIKY
                     QYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLGDKIDKKISGMQHNQTN
                     GIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRYRDDYRIFSNNRNDLEQ
                     IMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEIKASIRMNATNLDGDRE
                     IRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKITSKPNDLLPLIGILVD
                     IMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALKPNTEFMMIWFQRLTTI
                     FGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEGTIKDEEKYIKMSKKIY
                     ITEFDDFNDYPF"
     gene            1776..>3230
                     /locus_tag="LP245_002878"
     CDS             1776..>3230
                     /locus_tag="LP245_002878"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBL1520723.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMMARMNMILH
                     GVPIANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVL
                     APKSKADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGL
                     PANIFFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKT
                     RTIKDKYAYVAEFDEIVENDYNLNIPRYVDTFEEE"
BASE COUNT         1185 a          507 c          587 g          951 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tcctggtaga tatcatgata aataacccgg gttctttgcc
     1081 gcagtgtgtc ttaattatag ggcagttatt aaatttcgaa aatgagagta aggctagaga
     1141 aatagttgaa atgattataa acaaatatgc tttaaagcca aatactgaat ttatgatgat
     1201 atggtttcaa agattgacca ccatttttgg agaaatgttt gatagtgttt tatcatccga
     1261 atttgtatct aaaatcaaag atcctgtctc taatcagatg ttttctgtag actggctaaa
     1321 tgaagatgct aagaaatctt tttatgaagg gaccattaaa gacgaagaga aatatattaa
     1381 aatgagtaag aaaatatata ttactgaatt tgatgatttt aatgattatc ctttttaagt
     1441 gaaaatttag aatgaatata aaaaacatta caatctaatt tttttaaaaa aatgttatat
     1501 cggaagtaat ctcttgattt ctatactata agataagaaa accactattt aacaaggtta
     1561 ttcgaacctt attttaagtt acttattatt taatgtatcg aaaaaggtga aataggtttg
     1621 ttataataag aattaagtaa gacatgaatt gtctaagcaa atgtagctta tccatttcat
     1681 taaaatacat atggtgaaaa aacaagttca aatagtaact aattttttaa aaaactgatt
     1741 tataaaaaat acaacacgaa tgaggaaaat aaccaatgac agaacaaatc gaaaaaaatt
     1801 caaaaagctt atatcaggca ctgtggaatt ccgcagatat cctgcgttca aaaatggacg
     1861 ctaatgaata caagagctat ttactaggct tggtctttta taaatactta tccgacaaca
     1921 tgctgcggta tgtctccgtt ctattggagg aagaaacgga cgacctaaat aaagcacaag
     1981 acctttacgt tgaagcattt aaagatgcag atataaagga tgatctcttg tatgaactaa
     2041 aagatgagtt ttcatatacc atcgcacccg cattgacctt taccgcgcaa gtggcagcca
     2101 ttcatgatgg atcttttcaa ttagaagacc tggtacaagg tttccgtgac attgaacaat
     2161 ccagcgaaaa ctttgagaac ttatttgaag acattgatct gtattctaaa aaactggggt
     2221 caaccccaca aaaacaaaat aaaaccatcg cagatgttat gaaagaatta gaagggttaa
     2281 acatggcggg gcatgctggc gatgtcttag gcgatgccta tgagtactta attggccaat
     2341 tcgcatctga atccggtaaa aaagccggtg aattctatac cccacaaccg gtcgcaaaat
     2401 tgatgacaca aattgtttta caaggaaaag aagataaaaa aggcttttct gtttacgacg
     2461 cgaccatggg ttcgggctcg ttacttttga acgctaaaaa atattcccat caaccgggaa
     2521 ccatttctta tttcggacaa gagttgaata cgtctaccta taatttggcg cgtatgatgg
     2581 cgcgtatgaa catgattttg catggggttc ccattgccaa ccaacacttg cataatgcgg
     2641 ataccttgga tcaagactgg ccaacagaag agccaacgaa cttcgatggg gtgctcatga
     2701 acccaccgta ttctgcaaaa tggtcggctg ataaaggctt cttagatgac ccacgcttct
     2761 ctgcctatgg cgtattagcc cctaaatcaa aagcggactt tgctttctta ttacatggct
     2821 actatcattt gaaagatacg ggcgtcatgg ccattgtttt gccacatggg gtgctcttta
     2881 gagggggcgc agaagggaag atacgcaaag ccttgttaga aaatggtgcc attgacaccg
     2941 tcattggctt acctgctaac atcttcttta atacgtccat tccaacgacc gtaattatct
     3001 tgaagaaaga ccgtgcgaaa aaagatgtgc tctttattga tgcgtcacaa gattttgaaa
     3061 aaataaaaac gcaaaatacg ctacgagatt accatattga cgctatttta gaggcctata
     3121 aaacccgtac aattaaagac aagtatgctt atgtcgcaga atttgatgaa attgtggaga
     3181 atgattacaa cttaaacatt ccccgttacg tggatacctt tgaagaagaa
//
LOCUS       DAFEEZ010000136         2862 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.145, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000136
VERSION     DAFEEZ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.145"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            5..2377
                     /locus_tag="LP245_002879"
     CDS             5..2377
                     /locus_tag="LP245_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520724.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..>2862
                     /locus_tag="LP245_002880"
     CDS             2438..>2862
                     /locus_tag="LP245_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520725.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYA"
BASE COUNT         1144 a          455 c          621 g          642 t
ORIGIN      
        1 ggacatggca gaagaaaaag aaccactaga caatagtcgc ttgggaaaat ccaaaagaaa
       61 attagtacga ttgcaaaatg aattaaacga acaaattgag aagatgtttg aacaccagag
      121 aaagaccaac ggtcagccaa tgaacgataa gagaaatggg cattcttggt ttaggcaaca
      181 agaacgttta gaaaacaaag tgcatagtct gagagaagag atcaagcaac aagaaaaaca
      241 ggtagaaaaa cttgaaagac aagaagagct aaaggaaatg ggctataaca agtacggcgg
      301 cctggatatg acaatcgaaa atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg actttttcag ccgctacgat ccgaaaatac caacggaaat tggaaacatt
      421 agaacagctg aaagaaagat cagaaaaagg aaaagaaaat cttcttcctg aagtacaagc
      481 aattattgac agcggacgag tgacgcaatg gaaaaaaaat ccaaccattt attttttgaa
      541 agactatcga aaagttgctt tagaactgaa tgaaaacggg ggatttgagg aatcaaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctgc
      661 gccaactgat tctttgaagg agaaagaaaa cgatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tagaattgat
      781 cgatcaactc aaaacgttgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaagaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccca tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 aaaggaacaa aaacaaacgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaagcaaga
     1081 agtcaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcataccc attctcctga
     1141 agacgtgaaa gaacttttga attttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ctgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaagga ttttatgaga aaggacgtgg ctttgttcga gaaacagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt actacacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca gttaaaacct gaagactatc cgaaaatctt
     1501 tccgaaccgt gtctttgatt ttcaattgga taaaaaagga cagtcagaac ttcaagctgg
     1561 gattcaagcg gtagccaaca atattggaat acaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgggg ggcgtatgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcta caagtattca
     1741 tgaattagcc catgcaagaa tgcacaaatt ttcagaatta gataccgcaa ctaaagaatt
     1801 gcaggcagaa atgacttctt atattgtgtg caaacatttt ggaatggaca cttcggagaa
     1861 agctattcct tatattgcag catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 ggcggaacgt gggaaaatca tgaatgatgt cagccgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccaac cagcagaagt
     2041 gaagcaggag cataaaaata ctgtagaaac ggcagagaat aagaatattg tgcccgttgg
     2101 ttcactttgg atcgacaaga aagacgggaa agtaatggaa gaagatacgg gtcgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtga ttttaaaagg
     2221 aaaaagttat ggaaaagaga ttcaaacggc gttaccttca gaagaatttg cgctaggaaa
     2281 tccattccga ttttcacttg aaacagtgtc agaagtggcc aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg cgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg tttgaaaatg accgaaaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagact atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agatccaaga ctctaagcaa caatttaaag cagccacaga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtagaa aatcttcatt ttgagacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattatct
     2821 gaaggaagaa cgaaaactac cagagtggct gattgattat gc
//
LOCUS       DAFEEZ010000137         2789 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.146, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000137
VERSION     DAFEEZ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.146"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            204..1172
                     /locus_tag="LP245_002881"
     CDS             204..1172
                     /locus_tag="LP245_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBL1520726.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1165..2196
                     /gene="vanA"
                     /locus_tag="LP245_002882"
     CDS             1165..2196
                     /gene="vanA"
                     /locus_tag="LP245_002882"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBL1520727.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2202..>2789
                     /gene="vanX"
                     /locus_tag="LP245_002883"
     CDS             2202..>2789
                     /gene="vanX"
                     /locus_tag="LP245_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX"
                     /protein_id="HBL1520728.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSY"
BASE COUNT          822 a          537 c          685 g          745 t
ORIGIN      
        1 aattttttag gaaaatctca aggttatctt tactttttct taggaaatta acaatttaat
       61 attaagaaac ggctcgttct tacacggtag acttaatacc gtaagaacga gccgttttcg
      121 ttcttcagag aaagatttga caagattacc attggcatcc ccgttttatt tggtgccttt
      181 cacagaaagg gttggtctta attatgaata acatcggcat tactgtttat ggatgtgagc
      241 aggatgaggc agatgcattc catgctcttt cgcctcgctt tggcgttatg gcaacgataa
      301 ttaacgccaa cgtgtcggaa tccaacgcca aatccgcgcc tttcaatcaa tgtatcagtg
      361 tgggacataa atcagagatt tccgcctcta ttcttcttgc gctgaagaga gccggtgtga
      421 aatatatttc tacccgaagc atcggctgca atcatataga tacaactgct gctaagagaa
      481 tgggcatcac tgtcgacaat gtggcgtact cgccggatag cgttgccgat tatactatga
      541 tgctaattct tatggcagta cgcaacgtaa aatcgattgt gcgctctgtg gaaaaacatg
      601 atttcaggtt ggacagcgac cgtggcaagg tactcagcga catgacagtt ggtgtggtgg
      661 gaacgggcca gataggcaaa gcggttattg agcggctgcg aggatttgga tgtaaagtgt
      721 tggcttatag tcgcagccga agtatagagg taaactatgt accgtttgat gagttgctgc
      781 aaaatagcga tatcgttacg cttcatgtgc cgctcaatac ggatacgcac tatattatca
      841 gccacgaaca aatacagaga atgaagcaag gagcatttct tatcaatact gggcgcggtc
      901 cacttgtaga tacctatgag ttggttaaag cattagaaaa cgggaaactg ggcggtgccg
      961 cattggatgt attggaagga gaggaagagt ttttctactc tgattgcacc caaaaaccaa
     1021 ttgataatca atttttactt aaacttcaaa gaatgcctaa cgtgataatc acaccgcata
     1081 cggcctatta taccgagcaa gcgttgcgtg ataccgttga aaaaaccatt aaaaactgtt
     1141 tggattttga aaggagacag gagcatgaat agaataaaag ttgcaatact gtttgggggt
     1201 tgctcagagg agcatgacgt atcggtaaaa tctgcaatag agatagccgc taacattaat
     1261 aaagaaaaat acgagccgtt atacattgga attacgaaat ctggtgtatg gaaaatgtgc
     1321 gaaaaacctt gcgcggaatg ggaaaacgac aattgctatt cagctgtact ctcgccggat
     1381 aaaaaaatgc acggattact tgttaaaaag aaccatgaat atgaaatcaa ccatgttgat
     1441 gtagcatttt cagctttgca tggcaagtca ggtgaagatg gatccataca aggtctgttt
     1501 gaattgtccg gtatcccttt tgtaggctgc gatattcaaa gctcagcaat ttgtatggac
     1561 aaatcgttga catacatcgt tgcgaaaaat gctgggatag ctactcccgc cttttgggtt
     1621 attaataaag atgataggcc ggtggcagct acgtttacct atcctgtttt tgttaagccg
     1681 gcgcgttcag gctcatcctt cggtgtgaaa aaagtcaata gcgcggacga attggactac
     1741 gcaattgaat cggcaagaca atatgacagc aaaatcttaa ttgagcaggc tgtttcgggc
     1801 tgtgaggtcg gttgtgcggt attgggaaac agtgccgcgt tagctgttgg cgaggtggac
     1861 caaatcaggc tgcagtacgg aatctttcgt attcatcagg aagtcgagcc ggaaaaaggc
     1921 tctgaaaacg cagttataac cgttcccgca gacctttcag cagaggagcg aggacggata
     1981 caggaaacgg caaaaaaaat atataaagcg ctcggctgta gaggtctagc ccgtgtggat
     2041 atgtttttac aagataacgg ccgcattgta ctgaacgaag tcaatactct gcccggtttc
     2101 acgtcataca gtcgttatcc ccgtatgatg gccgctgcag gtattgcact tcccgaactg
     2161 attgaccgct tgatcgtatt agcgttaaag gggtgataag catggaaata ggatttactt
     2221 ttttagatga aatagtacac ggtgttcgtt gggacgctaa atatgccact tgggataatt
     2281 tcaccggaaa accggttgac ggttatgaag taaatcgcat tgtagggaca tacgagttgg
     2341 ctgaatcgct tttgaaggca aaagaactgg ctgctaccca agggtacgga ttgcttctat
     2401 gggacggtta ccgtcctaat cgtgctgtaa actgttttat gcaatgggct gcacagccgg
     2461 aaaataacct gacaaaggaa agttattatc ccaatattga ccgaactgag atgatttcaa
     2521 aaggatacgt ggcttcaaaa tcaagccata gccgcggcag tgccattgat cttacgcttt
     2581 atcgattaga cacgggtgag cttgtaccaa tggggagccg atttgatttt atggatgaac
     2641 gctctcatca tgcggcaaat ggaatatcat gcaatgaagc gcaaaatcgc agacgtttgc
     2701 gctccatcat ggaaaacagt gggtttgaag catatagcct cgaatggtgg cactatgtat
     2761 taagagacga accatacccc aatagctat
//
LOCUS       DAFEEZ010000138         2777 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.147, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000138
VERSION     DAFEEZ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2777
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.147"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..197
                     /locus_tag="LP245_002884"
     CDS             <1..197
                     /locus_tag="LP245_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520729.1"
                     /translation="WFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLIIAIIAVGLV
                     FNAAGVKDILLELFNRIIGA"
     gene            314..811
                     /locus_tag="LP245_002885"
     CDS             314..811
                     /locus_tag="LP245_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL1520730.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            898..1290
                     /locus_tag="LP245_002886"
     CDS             898..1290
                     /locus_tag="LP245_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL1520731.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            1274..>2777
                     /locus_tag="LP245_002887"
     CDS             1274..>2777
                     /locus_tag="LP245_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1520732.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPK"
BASE COUNT          839 a          517 c          596 g          825 t
ORIGIN      
        1 actggtttct atcaaacgct caatcactgg tgcttttagc aatcgttgtg attggcttgt
       61 atcttggctt caagcgtgag tttagcaaac tgattggctt tttaattatt gcgattattg
      121 cggttggctt agtcttcaac gctgctggag taaaagacat tttactagag ctattcaatc
      181 gcattattgg tgcttaaata aaaccgttct tttgtggaat ataagtggtt ttcttatgtt
      241 ccgcaaagga atggtacacc aaacgaagtg cggtagggat ttttgaatct ctacaaagaa
      301 aggacgtgaa tatatggacg atatgcaagt ctatattgcg aatttaggca aatacaatga
      361 gggcgaattg gtcggtgcgt ggtttacctt tcccattgac tttgaggaag tcaaagagaa
      421 aatcggcttg aatgatgaat atgaggaata cgccattcat gattacgagt taccctttac
      481 ggttgacgaa tacacttcta ttagcgaact caatcgccta tgggaaatgg tatcggagtt
      541 gccagaagaa ctacaatcgg agctatctgc tctgctcact catttttcaa gtattgaaga
      601 actaagcgaa catcaagaag atattatcat tcattccgat tgtgatgata tgtctgacgt
      661 ggcacgctac tacattgaag aaacgggtgc tttaggcgaa gtgccagcca gtcttcaaaa
      721 ctatattgat tatgaatcct atggtcggga tttagacctt tcgggaacgt ttatctcaac
      781 caatcacggg atttttgaaa tcgtctatta aatctgtcgg tacattctta ctggcagatt
      841 ttcttgttta cggggtagtc aaaagactat ccccattttt atgaaaggat tgattacatg
      901 aagaaaatac gaagctatac cagtatctgg tctgttgaga aagtgttgta ctccatcaat
      961 gactttagac ttccgtttcc cataaccttt acgcaaatga catggtttgt cgtgtcactc
     1021 tttgcagtta tgatacttgg caacttgccc cctctttcta tgatagaggg agcatttctc
     1081 aaatactttg ggattcctgt ggctttcaca tggtttatgt ctacaaaaac ctttgatggt
     1141 aaaaagcctt atggattttt gaagtctgtc attgcttatg cactgcgacg aaagctgacc
     1201 tatgcaggaa aaaaagtaac gcttggcaga aaccagccac aagaagccat tacagcagtt
     1261 aggagtgaat tttatggcat atccaattaa atatattgaa aacaatctgg tctggaataa
     1321 agatggggaa tgttacgctt actatgagct tgttccctac aattactcat ttctaagtcc
     1381 ggaacagaaa atacaagtac atgattcttt cagacagctt atcgcacaaa atcgtgatgg
     1441 caagattcat gctttacaaa tcagtacaga atccagcata ctttctgcac aagaacgttc
     1501 caaaaatgaa gtcactggaa agctcaaaac ggttgcctat gacaaaatcg accaacagac
     1561 agacgcttta atatccatga ttggcgaaaa tcaagtggac taccgtttct ttatcggttt
     1621 taagttgctt ctcaacgatc aggagttttc tatgaaaagt cttaccgttg aagcaaaaaa
     1681 tgcttttact gattttgtct atgatgtgaa ccataagctg atgggcgatt ttgttagtat
     1741 gagtaatgat gaaatcctgc gttttcagaa gatggaaaag cttttagaaa ataaaatctc
     1801 ccgtcgtttc aaaatccgaa gattagataa ggatgacttc ggctatctga ttgaacacct
     1861 ttacggacag acaggcactg cctatgaaga gtatgagtat cctctatcaa agaaaaagct
     1921 ggaacatgaa acactgatta aaacctatga cctcattaag cctactcgct gtctggtgga
     1981 agaaaaacag cgatatttga aaatccagca ggaagacgaa accgcctatg tagcttactt
     2041 taccatcaac agtattgtcg gcgaactgga cttcccgtcc tctgaaatct tctactacca
     2101 gcaacagcaa tttacctttc cgattgatac gtcaatgaat gtggaaattg tagcgaatcg
     2161 taaagcccta tctactgtcc gcaataaaaa gaaagaactg aaagacttgg ataaccacgc
     2221 ttggcaaagt gataatgaaa ccagctctaa tgtggcggaa gctctggaaa gtgtgaacga
     2281 gctggaaacc aatttagacc aaagcaagga atctatgtat aagctgtcct atgttgtaag
     2341 ggtatcagca aatgaccttg acgaacttaa acgtcgttgt aatgaagtga aagatttcta
     2401 tgatgatttg agcgtgaaac tggtacgacc ttttggggat atgctgggct tacatgaaga
     2461 atttttacct gccagcaaaa gatatatgaa tgactatatt caatacgtga cctctgattt
     2521 cctcgctggt ttaggttttg gtgctactca aatgctgggt gaaaatgagg ggatttatgt
     2581 tggctacagc ttagatactg gacgcaatgt ctatctgaaa cctgctcttg ccagtcaagg
     2641 ggttaagggt tcagtaacca atgcgttagc gtctgccttt gtcggttcgc tgggtggtgg
     2701 taaatccttt gcgaataacc ttatcgtcta ttatgcagtg ctttatgggg cacaagcagt
     2761 gattgtagac ccaaaag
//
LOCUS       DAFEEZ010000139         2769 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.148, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000139
VERSION     DAFEEZ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.148"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            75..692
                     /locus_tag="LP245_002888"
     CDS             75..692
                     /locus_tag="LP245_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520733.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            696..1145
                     /locus_tag="LP245_002889"
     CDS             696..1145
                     /locus_tag="LP245_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520734.1"
                     /translation="MTDIVKIKQSGVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            1145..1639
                     /locus_tag="LP245_002890"
     CDS             1145..1639
                     /locus_tag="LP245_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520735.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            1653..2084
                     /locus_tag="LP245_002891"
     CDS             1653..2084
                     /locus_tag="LP245_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520736.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            2086..2223
                     /locus_tag="LP245_002892"
     CDS             2086..2223
                     /locus_tag="LP245_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBL1520737.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            2260..2553
                     /locus_tag="LP245_002893"
     CDS             2260..2553
                     /locus_tag="LP245_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520738.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            2550..>2769
                     /locus_tag="LP245_002894"
     CDS             2550..>2769
                     /locus_tag="LP245_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBL1520739.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGN"
BASE COUNT         1007 a          403 c          604 g          755 t
ORIGIN      
        1 ggagctttga ttattgcaac tgttgatgat ccaaaacaga atgttttcac tcttgagaaa
       61 gttggggtga tttgatggtt aaagtaaaga gaatgatgga gactgatgaa tctggtgtta
      121 aacgtcaatt tatgccaatt acacatgttt ctgcagtttt aggcttagaa aaaatgatat
      181 caggacaatc aaaagttctt tcggttaatg gtaaatatgg tgcagtcatt ttaacgaaag
      241 ctgatttagg attagagaat gcaattactg aactacctta tgcaagcgag acaagcgatg
      301 gtattcttac tgctgaaatg tttcaaaaga tcgtaaatgg agaaggtgga acatatattt
      361 tgccgattgc tactcctgaa caattaggag gtataaaagt tggggaactc ttagaagtta
      421 ctgaagaagg tgttttatct gcaactaagc aaacagactt caatttctct gaagaattaa
      481 agggaaaatt agaatctcta aaaatattaa aagcaggtgc aaatatatca attgcagaag
      541 atggaacaat tagttctaca ggtggtagtg ggactggtgg tgttaatcag tcatatgtag
      601 atcaaaaatt ccaagaagct gtaaatcaag cagaaaatta cacaaacgaa agaattccaa
      661 attttacttt tgaaaaaatc ggggaggtat agaaaatgac agatatcgta aaaataaaac
      721 aaagcggtgt acaggtttat ccacaaactc attggaatgc tatagaaggc aaaccaacaa
      781 cggtgaaggg agataaaggc gatcctggcc aagcagcaac aattaccata ggaaccgttt
      841 ctagtggttc aaccgcttct gttacgaatg taggaacatc atctgcagct agatttaatt
      901 ttgttttacc aaagggagat aaaggtgatc ctggaataaa tgccacaact acagctgtag
      961 ctacaactac agcaaatggg ttgatgtcgt ccacagataa aactaagttg gatggaattg
     1021 cagctggagc acagaaaaat ccaggtaatg ctacaactac gacagcaggt ttaatgtcag
     1081 caaccgataa agtgaaactt gatggattag cgaatattac atttgagaaa gtggggacgg
     1141 tttaatggct gatattgtgc aattaaaaga agacggagtt gctaaatact taaaaacgca
     1201 tgtagaagct attgatggta aagaagcatt ggtgcagaca gatggagacc aagccattgc
     1261 aggacataag aatttttcag gttctgtaac aatcaataat aaacgtgttt tgacgactga
     1321 tgataacaga tatgaagtgg taaatctggt tgtcactaac ggtaatacag ggacagcaaa
     1381 gctttatcgt gaaggaaaaa cagtttctat atattttgtg gctttaaacg gaaaaagtag
     1441 tggcgggaat gattcggtta ttttaactgt tccagaaggc tatcggacac caattagttt
     1501 tgaacaactg gttgggtcaa tagaccgttc tactttgaac agtgctcaac tatctattgg
     1561 cgcagacgga gccattaaat ggagaagaaa ttcaagttat ggatcagctt attcatttgt
     1621 tatcacttat tcaatttaag ggaggaaatc taatgaaagt agtttacaaa tcaatcaagc
     1681 cttacggatt cgagcaaatc attttgaaca atcaagaaaa tatccctgaa aactgtacag
     1741 agattaaacc accagttcct aactggagac caagatttga ttttgataaa aaacagtggg
     1801 ttgagttagc tactgaagaa gagaaaaaag ggaatgctgt tgatagcgta gatgaattgg
     1861 ctaatattaa ggcattatac gaaacgctga aggcagaaaa tgatgaattg aaacagctaa
     1921 attctaaagc aatgctaaac aatgtagcaa tcaagcaaga aaatgtctta ttgaaagaaa
     1981 agtcagaaag tttagcgcag ttgaattcaa aaacgatgct tgcttctgta caaaatacca
     2041 aggaaatcga agaaatcaaa aaacaattac aaggtgggaa gtaacatgta ttcatatgaa
     2101 gatatcaaac taatgtatga ctggggctgt ttcactaacg aacaagtaat ggttttcgtt
     2161 ccattatgca ttacagacga agaagcagat aaaatcatta ataaagataa gagcgcatct
     2221 taattgatgc gtttttattt aaggtaaagg agttgtcaca tgattaattt aggggaatgg
     2281 ggaatgatag caggatcaat aaccgctatc gtttctttga ttttattagt aattagaccg
     2341 attgctgcat ctttctcgaa aattactgag actctttcaa aagtaagcca caatttagat
     2401 ttgctgacta aagatttaga atcgagcaaa tcagatcgat tgatgattca tgaagaacta
     2461 aagaaacacg atgaaagatt agatacacat acagaaaaat tggtggaaca cacgcaacaa
     2521 atcaaaactt tgtttaggga gagaagaaaa tgaataataa aacgttcgaa gtactaaaat
     2581 ggttcgcact ggtaattatt cccgcactag ctactttcgt ggggttagtt ggtaaagcgc
     2641 tcaattggca gtacacagat atctgtgttg tcatcattac tggttttggc gcgtttttag
     2701 ggagtgtgtt gggtgtatca aatcgaacct acaaaatgtt ctcggctgaa agcgaagaag
     2761 gaggaaaca
//
LOCUS       DAFEEZ010000140         2719 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000140
VERSION     DAFEEZ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.149"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="LP245_002895"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="LP245_002895"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL1520740.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         1065 a          420 c          556 g          678 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatca
//
LOCUS       DAFEEZ010000141         2640 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000141
VERSION     DAFEEZ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.150"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            724..2550
                     /gene="ltrA"
                     /locus_tag="LP245_002896"
     CDS             724..2550
                     /gene="ltrA"
                     /locus_tag="LP245_002896"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL1520741.1"
                     /translation="MLKKNKLRYNEYYDMQHIYDELYAQSKNGNNFYKLLEIIGSEQN
                     ICLAYRNLKSNSGSKTAGTDGMTIDDIKQLSNAEIVATVRESLSNYRPKSVRRVFIPK
                     AGSDKMRPLGIPCIWDRLVQQCILQVLEPICEPKFHNHSYGFRANRSAHHAVSRVTTL
                     INLSKYHYCVDVDIKGFFDNVNHGKLLKQIWTLGIRDKRLICIISKMLKAEIDGEGVP
                     EKGTPQGGLLSPLLSLIVLNELDWWVSSQWETFQPKNRSKNGWLQYAKKYTKLKSGFI
                     VRYADDFKIMCSTYGEAQRFYHSTVDFLNKRLKLEISPEKSKVVNLKKNSSDFLGFKI
                     KVIPKGRTKHGYVAKTDMNQKALKKAKTNLKLKVKDIARHTTGFNISRYNLTVIGMQN
                     YYCIATNVYNNLTEVSYALLPTIRIRLRNIAKSVPFESTSSEFQSRTKGIRPKTKIVM
                     IADNPLLPIQGVQHKNPMNFSQDICNFTKQGRNKVHEDVVVVTKEEIRALLENENPAD
                     SVEFNDNRISAYIAQQGNCYVMNRRGTPSTLICIHKSDKGDNLDRYSNLAFVEIPIAK
                     AILTESADEAKSLLKGYVLNSQQKKKLNRIRTNYGYQTITGK"
BASE COUNT          948 a          461 c          584 g          647 t
ORIGIN      
        1 aaaagagtag gcacagcact tcattaaatc aatatttaat gtgtgttgga gaactaaaca
       61 cacgaatagt cgaatgacgg ggtaacgccc tgaaaggcta ctttaatact ctgactggca
      121 gaaacttgag taaacaaggc tctgtcagaa gctcggtgaa gtcggcagac agacaccgta
      181 acagataatg ctgacgaaag attcccagag gtgggcgttg tgtcctatat gccggaagtc
      241 tataaaatat ctatggttag aatgtagatg agaggtctac tgacgaatcc ttgaatgtac
      301 aggtctatat cggggctgga tagaaatgtc cagtgacaca aacagtgtcg ctactgtggg
      361 tgagtaagac tccgcattta tgaaaatcca tataacgtta aaggcgttat caaggtagca
      421 ggcttataga ggaaacctaa ggatatatgt acagatagtg tgtttggaac gttgaaagct
      481 gacaacatgg agattttact gtctgtgaag tgttcacatc agaaagttat tgtgagatta
      541 gcaatgatat aaggtgtgtt aatgtcagtg agagtggtgg cacagtacct atgaaaccgt
      601 gataacaagc ggtggaggga tagccactag tcatatgaag aatagaatta ctaagaaaaa
      661 tggtatgggt tcgagtaaga ctaagagatg tacttgctcc tgcaaacaag gagggtacag
      721 accatgctaa agaaaaacaa gctccgctat aacgagtatt atgatatgca acatatttat
      781 gacgagttat acgcacagag caagaacggt aataactttt ataagttact tgaaattatt
      841 ggttcggaac aaaatatttg tttagcttac cgtaatctga aatcaaacag tggcagtaaa
      901 acggctggaa cggatggaat gacgatagac gatataaaac aactcagcaa tgctgagatt
      961 gttgctaccg ttcgggaaag ccttagcaac taccgcccca aatcagtcag acgtgttttc
     1021 attccaaaag ctgggagcga taaaatgcgt ccattgggga ttccgtgtat ctgggacagg
     1081 ctggtacaac aatgtatcct gcaagtccta gagccgatat gcgaaccaaa gttccataat
     1141 cattcctatg gattccgtgc gaatcgaagt gcccaccatg cagtcagcag agtaacgaca
     1201 ctgataaatt tatcaaaata tcattactgt gttgacgtag acattaaagg atttttcgat
     1261 aatgtcaatc atggaaaact attaaaacaa atctggacac ttggtattcg ggataaaaga
     1321 ttgatttgca ttatcagcaa aatgctgaaa gccgaaattg acggcgaggg tgtcccagaa
     1381 aaaggaacgc cacaaggcgg tctgttaagt ccactgctct ccctcatagt ccttaatgaa
     1441 ttagactggt gggtaagcag tcagtgggaa acattccagc cgaagaaccg cagtaaaaat
     1501 gggtggcttc aatacgcaaa gaaatatacc aaactgaaaa gcggttttat tgtacgttac
     1561 gctgatgatt ttaaaatcat gtgttcaacc tatggagaag cacaaagatt ttaccacagt
     1621 accgtagatt ttcttaataa aaggctgaaa ttagaaatca gtccagagaa atcaaaggta
     1681 gtaaatctga agaaaaattc atcagatttt ctggggttca aaatcaaagt cattccaaaa
     1741 ggaagaacga aacacggtta tgttgccaaa acagatatga accaaaaagc attaaagaaa
     1801 gcgaaaacaa atctaaagtt aaaggtaaaa gatatagcca gacatacgac tggcttcaat
     1861 atcagcagat ataatctgac agttatcggt atgcagaatt actactgcat agcaactaac
     1921 gtatataaca acctgacaga agtaagttac gctctcttac cgaccatacg aatccgttta
     1981 aggaacattg caaaatcagt tccatttgaa agtacaagtt cagaatttca gagcaggaca
     2041 aaaggaatca gaccaaaaac aaaaatagtg atgattgcgg ataatccgct attgccgatt
     2101 caaggagtac aacacaaaaa tcctatgaat ttctcgcaag atatttgtaa ttttacaaag
     2161 caagggagaa acaaggtgca tgaggacgtt gtagttgtaa caaaagaaga aatccgagcg
     2221 ttgttggaaa atgaaaaccc tgccgatagc gtagagttta acgacaatcg tatttcggca
     2281 tatatcgcac aacaaggcaa ctgctatgta atgaatcgtc gaggaactcc gtccactctg
     2341 atatgtattc acaaatcaga caaaggagat aaccttgaca gatattctaa tctggcattt
     2401 gtggaaattc ccattgcaaa ggcaatccta acagaatcag cagacgaagc aaaatcactg
     2461 ttaaaaggtt atgttcttaa tagtcagcag aagaaaaaac tgaacagaat acggacgaat
     2521 tacggatacc agacaataac tgggaaataa cttataaatc tatttggata tgatggaacg
     2581 ccgtatgaag cgaaagtttc atgtacggtg tgaagcgggg gaaaacttgg agataacatc
//
LOCUS       DAFEEZ010000142         2509 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000142
VERSION     DAFEEZ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.151"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            349..1929
                     /locus_tag="LP245_002897"
     CDS             349..1929
                     /locus_tag="LP245_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBL1520742.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            2127..2351
                     /locus_tag="LP245_002898"
     CDS             2127..2351
                     /locus_tag="LP245_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBL1520743.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
BASE COUNT          892 a          404 c          530 g          683 t
ORIGIN      
        1 ttttctttta gtcagctgac aaaaaaatat ttgactctta tggtttggtg gctttttcat
       61 tcgctgaatc catgctatac tgattcagtt gtagtagttg acaaaggttg tgaaaaagct
      121 atcctgcatt aagtaataag agcagccaag caaaaacagc ttttcgtatt tttggcttgg
      181 gtgggcttat tgctgatagg ctgtctctag aacgccgttt actcggaaaa agagactgct
      241 acacggcttt tgtcacagcc ctatatgaaa ttgtctttct ttaagagatc ggacaatctg
      301 tgcctagaga aaatataaat aattgaatgg aagaaatgga gttaggttat gaataatcca
      361 aaattaaagc aacaagtgga caatcgcaga acttttgcga tcatttccca tccggatgct
      421 gggaaaacaa cgattacaga acaattacta ttgtttggtg gggctatccg tcaagccggg
      481 accgtaaaag gcaaaaaaac aggtaatttt gccaaatcag actggatgga aatcgagaaa
      541 caacgtggga tttctgttac tagttctgtt atgcagtttg attatcaagg gaaacgagta
      601 aatatcttgg atacaccagg acatgaagat ttttctgaag atacttatcg tactttgatg
      661 gccgtggata gtgcggtcat ggtaatcgat agtgcaaaag ggatcgaagc acagacaaag
      721 aaattattcc aagttgtaaa aaaacgtggc atcccgatat ttacttttat caacaaacta
      781 gatcgtgatg gtcgtgaacc attggaattg ttagaagaat tagaagagct attagatatc
      841 gaatcttatc cgatgaattg gccaatcggt atgggtaaag ggctagaagg tctttatgat
      901 atctaccata atcgtgtaga gttttatcgt ccggaaaatt atcaggatga acgattagta
      961 gaattggatg aagatggact gcttcccgaa aatcatcctc taactgaaaa ttccttatat
     1021 gaacaagtct tagaagaagt agaactaatc aaagaggctg gagatgcatt taatcaagaa
     1081 aaaattgctc gtggcgatca gacaccagta ttttttggtt ctgcattgac taacttcggt
     1141 gtacagactt ttttagagac tttcgttgaa ttggcaccag ctccttatgg acacaaaaca
     1201 caagatgatc agatggtaag tccttatgag gaagaatttt caggtttcgt attcaagatc
     1261 caagcaaata tgaatccagc ccatcgtgac cgaatcgctt ttgtccgaat ctgttctgga
     1321 acattcgaac gaggaatgga tgtctggttg gaacgtacaa ataaaaaact gaaattaagc
     1381 aatgtcacac aatttatggc agattcgaga gaaaacgtcg aaaaagcagt agcaggcgat
     1441 atcatcggtg tatatgatac aggcaattat cagattgggg atacattgtt cgaaggaaaa
     1501 ctaaaagttg cttatgaaga actcccttca tttactccag agctgtttat gaaagtgact
     1561 gcaaaaaatg tcatgaaaca aaaatccttc cacaaaggaa tctatcaatt agttcaagaa
     1621 ggagcgattc agctttataa aacatatcta acggaagaat atatcattgg agctgttggt
     1681 cagctacaat tcgaagtatt ccaatatcgt atgttaaatg agtataacgc cgaagtaatc
     1741 atgtctccaa tgggacacaa aatcgctcgc tggatcgatc cagaagattt ggatgagaag
     1801 atgagttcaa gtcgcaatat cttggctcgt gaccgtttcg accaaccgtt gttcttattc
     1861 gagaaccaat ttgcagaacg ctggtttgcg gataaatatc ccaatgtaaa attaaaaagt
     1921 ttgatgtaaa gaagtcttga cacaagctgc cctgcatcaa gtaataagaa tagccaaaca
     1981 aaaacagcct ctcatatttt gtttagagcc gtgacggatt ttccgtgacg gctcttttta
     2041 ctatattaaa atcatagaaa tgtctaatca aaaaaatata aaaattattt tgcgtacata
     2101 tgattaaaga aaggagagtg tgacacatgg aaacagaatg gcaaagacgt gaaagaaaaa
     2161 aacagaaaaa agaagagatg ttacgattat gtcgattatt agatgtaaaa gactgggaca
     2221 aaaacgagca aattgcacaa aaagtacgat caatcatcca taaagaggaa aaagttaaaa
     2281 ataaagacac gcgtagaact gaaaatgaaa agagaaaagt acaaaagaaa agagaaaaat
     2341 caaaaagcta gaaagaaaaa gaggctgaga cagaagcgtt taactccaag aaataagctg
     2401 gaattcacaa aaatttgaaa agcaattttc gtgaatttca gcttatttcc gaaggagttg
     2461 cttctgcttt cgccgtttat acgtgtttag agcgtgagac aaaagtgtt
//
LOCUS       DAFEEZ010000143         2398 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000143
VERSION     DAFEEZ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.152"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            207..2069
                     /locus_tag="LP245_002899"
     CDS             207..2069
                     /locus_tag="LP245_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1520744.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="LP245_002900"
     CDS             2069..>2398
                     /locus_tag="LP245_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1520745.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DAFEEZ010000144         2204 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000144
VERSION     DAFEEZ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.153"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            274..1644
                     /locus_tag="LP245_002901"
     CDS             274..1644
                     /locus_tag="LP245_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4357 domain-containing protein"
                     /protein_id="HBL1520746.1"
                     /translation="MMDKSNEEQTTLYTKYWRRLEEVFDNSKGMEDFFRYYLAAITGE
                     YSAKHILYQAFKDYWHKERDVSSDAELLQKLVRYAGYFARLYYNKPEGKYSEVLSDFQ
                     SMESMMPAPFVLGLSEWYYHDQFITEDQYIDAIKVVNDYQLRRYFNGDDTSRVSKAFP
                     SYLKSVRKYAKANGYENIVDIVIYVLVTRNQSNNMALPSDKALKSNLLNANAYAMRLA
                     RWLLEKIENRENSATLDMSNLSIEHIMPQTSTSYWEEKAGTSGEEYTGLVNTIGNLTL
                     VTNPDNSAAGNKDFETKKKIFEDTLHIRMNKDLYELTEWTSSDISARSEALINELITM
                     YPYLRSSGDYEHDGNREIFLEAQGIKATGYLNEDETVIIHSGSEIYSKIKDIASDSLD
                     ETRQELLDNGIIEETIGGLQFVQDYTASSVSNAAALLLGGSRNGWDYWKYDNGISIND
                     SLRNKK"
     gene            1665..1949
                     /locus_tag="LP245_002902"
     CDS             1665..1949
                     /locus_tag="LP245_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520747.1"
                     /translation="MDKNKLRYAILKLRDEKKNPFIELKGQVPEEDILEQTKFLSRNG
                     LLESMVWADNTVHIWGSVSLEGEKYLVENSGLAKAYALAKEVKNWIPFWG"
BASE COUNT          755 a          320 c          464 g          665 t
ORIGIN      
        1 ccttgaatgt tataaaagta tctgtataat gttcagtata ttttgatgaa cgcatatgta
       61 gtcctcattt cttgggagtt ttgagactac tatatgcgtt ttttgttgat ttaccaacat
      121 gtttagacat tttcctctag gaaaaaatta actagcacca cgcgtattgt ttatattaaa
      181 ttagatgacc gtgataatgc acagcaaatt tttgaaagta tcaattctac cggtgaaaga
      241 ttgactgcct cggatttgat tcgaaacttc atcatgatgg ataaatctaa tgaagagcag
      301 actacgcttt atactaaata ttggcgtagg ttggaagaag tctttgataa ttctaaagga
      361 atggaagact ttttcagata ctaccttgct gcaataactg gggagtattc agcaaagcat
      421 attctttatc aagcattcaa agactattgg cataaagagc gcgatgtatc aagtgatgcc
      481 gaattgctcc aaaaattagt gcgatatgct ggttattttg cgagacttta ctataacaaa
      541 cctgaaggaa aatactcaga agtattgagc gatttccaaa gtatggaaag tatgatgcct
      601 gcaccttttg ttttgggatt atctgaatgg tactatcatg accaatttat cactgaagac
      661 caatatattg atgcgattaa ggtagtgaat gattatcagc ttaggagata ttttaatggg
      721 gatgatacaa gcagagtgtc aaaagcattt ccttcatatt tgaaaagtgt taggaagtac
      781 gctaaagcta atggatatga aaatatcgtt gatattgtaa tttatgttct tgttactaga
      841 aatcaatcaa ataatatggc acttccatct gacaaggcat tgaaatctaa tctattgaat
      901 gccaatgctt atgcgatgag attggcccgt tggttacttg aaaaaataga gaatcgagaa
      961 aattcagcaa cacttgatat gagtaacttg tccattgaac acatcatgcc acagactagt
     1021 acttcatatt gggaagagaa ggctggtaca tcgggggaag aatacacagg attagtaaat
     1081 accattggta atttaacact cgttacaaat cctgataatt cggccgcggg aaataaagac
     1141 tttgagacca aaaagaaaat ctttgaagat acccttcata ttcgtatgaa taaagatttg
     1201 tacgaattga ctgagtggac atcatcggat atttctgcca gaagtgaagc tctaatcaat
     1261 gaactgatta ctatgtatcc ctatttgaga tcgtcgggcg actatgaaca cgatgggaat
     1321 agggaaattt tcttagaggc gcaaggaata aaagcaactg ggtatttgaa cgaagacgag
     1381 accgtgatta tacattcagg ttcagaaatt tattctaaga ttaaagatat tgcatctgat
     1441 tcgctagatg aaactcgcca agagctgttg gataatggaa tcattgaaga aacaattggg
     1501 ggactacaat ttgttcaaga ttacactgcc tcatctgttt cgaatgcagc agctctgcta
     1561 ttagggggta gccggaatgg ttgggactac tggaaatatg ataacggaat aagtattaat
     1621 gattcgctaa gaaataagaa atagagcata gaggtggtgt taggttggat aagaacaaac
     1681 taagatatgc aattcttaaa ttgcgtgatg aaaaaaagaa tccttttatt gagcttaaag
     1741 ggcaagttcc agaagaagat attttagaac aaactaaatt tctttcgcgc aatggcttac
     1801 tagaatccat ggtttgggcg gataacactg ttcatatctg ggggagtgtt tctctggaag
     1861 gggaaaaata tttagttgaa aactcaggtc ttgctaaggc gtatgcattg gcaaaagaag
     1921 ttaaaaattg gattccattt tggggctaag ataagttttt aaacggagaa ggtagcaaat
     1981 cataattggt ttgttgcctt ttttgattgc ccaaaaagaa aaatgacaaa gtatagagat
     2041 aaatgacata gtacacggga aaaatgacat tgtatcaccg acaacgtcta aatagatgtt
     2101 gatatatata cgttccgtac aaataattat aaaaatttaa atgatttgag tagaagtatc
     2161 agtgaatatc tcaaggggaa tagctatctc aagattcgat tttc
//
LOCUS       DAFEEZ010000145         2194 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000145
VERSION     DAFEEZ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.154"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     misc_feature    109..234
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            278..802
                     /gene="infC"
                     /locus_tag="LP245_002903"
     CDS             278..802
                     /gene="infC"
                     /locus_tag="LP245_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBL1520748.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            874..1074
                     /gene="rpmI"
                     /locus_tag="LP245_002904"
     CDS             874..1074
                     /gene="rpmI"
                     /locus_tag="LP245_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBL1520749.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            1127..1486
                     /gene="rplT"
                     /locus_tag="LP245_002905"
     CDS             1127..1486
                     /gene="rplT"
                     /locus_tag="LP245_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBL1520750.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            1838..>2194
                     /locus_tag="LP245_002906"
     CDS             1838..>2194
                     /locus_tag="LP245_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBL1520751.1"
                     /translation="MATVWMGLALVGNTFSPNSAMEGQGVIDVLTHIYTTGPAEYAKS
                     ILVNVFFGAFFGRVLVDSGIAATLIRKVVELGGDKPRITMSLLCIVTAVIFMSMTGIG
                     PVISIAVIVLPILMSLG"
BASE COUNT          735 a          384 c          479 g          596 t
ORIGIN      
        1 aatcactgct agaaagcctg ctaatctaat cattttcaga aaaggaagac aaactgtatg
       61 aaaaacattg acaaaaagat tagtttttgc tatactataa tggttgagaa ataaaagcag
      121 aagcacccgc ttctcgcctt agttgataat gtcactgggc tagatagttt tcactggttc
      181 tattaggtga agtacgcgcg ggttctgtaa gagaactcgt ttttttattg ccgtttattc
      241 ggtaagcttt tctttctctc ataatatttg gaggtgaatg accatagcaa aggatatgat
      301 ggttaacgac ggcattcgtg cacgagagtt acgattgatc ggttcagatg gtgagcaatt
      361 aggagttaag acaaaagcag aagcattgaa tattgcagaa caagcaaact tggatcttgt
      421 gttagttgcc cctggtgcga aaccaccagt tgcgcgaatc atggactacg gtaaataccg
      481 tttcgaacaa caaaagaaag accgcgaagc gcgtaaaaaa caaaaagtga tcaatgtaaa
      541 agaagttcgc ttaagtccta cgatcgactt gaatgacttc aatacaaaac ttcgtaatgc
      601 acgtaagttc ttggaaaagg gcgataaagt gaaagcttct atccgtttca aaggccgtgc
      661 cattacccat aaagaaattg gtcaaaaagt cttgaatcgc ttagctgaag aaactgcgga
      721 tattgcaaca gtggaacaaa aagcgaaaat ggacggacgc agcatgttct tgacgctggc
      781 accgaaaaac gacagtaagt aatttgaatg actaactggc tgttggacag ccgatagtcg
      841 gataacgaaa gattttgagg aggaaatata gtcatgccaa aacaaaaaac acaccgcgga
      901 tcagcaaaac gtttcaaacg tactggtaaa ggcggattga aacgcttccg cgcgtttaca
      961 agtcaccgtt tccacggcaa aacaaaaaaa caacgccgtc aattgcgtaa agcaagcatg
     1021 gtttctagtg gcgacttcaa acgtattcgc caacaactag caaaaatgaa ataagaagta
     1081 caaataacag aatctgaaga tttattttta ttaggaggaa ttatacatgg cacgtgttaa
     1141 aggtggaaca gtaactcgta aacgtcgtaa aagagtgcta aaattagcaa aaggttacta
     1201 cggttcaaaa cacactttat ttaaaacagc aaaagaacaa gtaatgaatt catacaacta
     1261 cgcatatcgc gatcgtcgtc aaaagaaacg cgacttccgt aaattgtgga ttgctcgtat
     1321 caacgcagca gctcgtatga atggcttgag ctactcaaaa ttaatgcacg gtttgaaagt
     1381 tgctgaaatc gacatcaacc gtaaaatgtt agctgacttg gctgttaacg atgcagcagc
     1441 atttactgca ttggctgacc aagcaaaaga agctttggct aaataagcta aacaattata
     1501 aagaggaaag aagataacga aaagttatgt tctttcctct ttttttattt acaatcctcc
     1561 atcaaatgaa acaggacaat aacgtataag tctaaaataa cataattaag gttttttaat
     1621 tgaaaactga acatttatgg tcatccttta atgaaagcgc taactacata agttagaatg
     1681 agtttgactg atatattagt ttgcttatca gaaaaacaaa atggacggag gaataacatg
     1741 agtgatatta ttattggtat tttgttagtt atctcattct ttttcatggt ctggtactgt
     1801 gtaaaaggct acaacttgat ggtcggcttt tgtcatcatg gctactgtat ggatgggatt
     1861 agcgctagtc ggaaacacgt tttcaccaaa ctcggcgatg gaagggcaag gagtaattga
     1921 tgtgttgacg catatctata cgacggggcc agctgagtac gccaaatcga tcttggtaaa
     1981 tgtcttcttt ggtgcctttt tcgggcgtgt tctagtagat agcggaatcg cagctaccct
     2041 gattcgaaag gtagttgaac ttggagggga caagccaaga atcacgatga gcttactatg
     2101 tattgtaacc gctgttatat tcatgtcgat gacaggaatc ggaccagtga tttctattgc
     2161 agttattgtg ttgccgatct tgatgtcatt aggt
//
LOCUS       DAFEEZ010000146         2189 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.155, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000146
VERSION     DAFEEZ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2189
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.155"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(325..528)
                     /locus_tag="LP245_002907"
     CDS             complement(325..528)
                     /locus_tag="LP245_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520752.1"
                     /translation="MSQLGKCYSLSKSNRKVYTLFISDSAKEGFTLGFSISFKKGTKN
                     TSISHNNRELTDSQKINGLSGRK"
     gene            complement(987..1952)
                     /locus_tag="LP245_002908"
     CDS             complement(987..1952)
                     /locus_tag="LP245_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBL1520753.1"
                     /translation="MSKRGTIINEWENLTALSNRRLSVQTLTTPLKIQWSIDRITIVG
                     KLKENIYYHTQNDVLILDFEQLMRLNENNGYVKSVGLNGWQIVDKHDENIAYIEILKY
                     QEGQGRIDFNPNKISQFLAGSMKNFIHDLFLEPHFSRADIACDIIDVPDDFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQETKRKIVPPEIKTWWRLELQ
                     LRRGKATDWYAMVHESLDSFASPHFLPTDTKHTDRIMIAGLISDQNLWAGLARHTKYK
                     YRNLLKKESQSDELVNHLRETFSESADVLKKELDTWLLGLDVTEE"
BASE COUNT          629 a          506 c          346 g          708 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggctttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cgcgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaca ttttcctaat tgtgacatgg ctgtcacaat
      541 tccaaacgct ctccgagggt tttcgctgtc acaagtgaca acgaaaaaag gagccgaaag
      601 cgtgtcacgc tctcaactcc ttttacgctt tattttgctt cacgcaaaat aatcgcttat
      661 cttaaacatt gacgtaaatt tactctcact tatctgactt ttttactcgg tatcactccg
      721 agtaagccgt catattcatt gggataatct cgtctgcttc gctctaattt tccagagtga
      781 ggggtaactc cttcccccga attaccccaa agagtgacac tgggatatcc ctaaatttat
      841 tataaaaagc caagtctctt tgcgcaactg ttttatccaa gtcggcattt gcggattcgt
      901 tagcgttttt tcgctcttgc tgcaaacgca cgacccacca tgccgacttg tgctgaaaat
      961 aaaaaagtgg acaaaaattc atccactcat tcttccgtca cgtccaaccc caaaagccac
     1021 gtatccaatt cttttttcaa aacatctgcc gattccgaaa atgtctctcg taaatgatta
     1081 actaactcat cactttggct ttcttttttc aacaaatttc gatatttata ttttgtatga
     1141 cgagccaagc cagcccataa attttgatct gaaatcaatc ctgcaatcat aattctatca
     1201 gtatgctttg tatcagtcgg caaaaaatga ggacttgcga aactgtctaa actttcatga
     1261 accatcgcat accaatcagt agcttttcca cgccgtaact gcaattccag tcgccaccaa
     1321 gtttttattt ccggtggtac aattttccgt ttggtttctt gttccaattt tttgttgtac
     1381 atccttattt gtcgctcact ggcacgacta ccccaatatg ccgtttccag cttcccagac
     1441 cgcccataga ttggtttgaa tgaaacaggg tcaaccacac gatattgcgt aataaaatca
     1501 tcaggcacat cgataatgtc gcaagcaata tcagcacgtg agaaatgtgg ttctaaaaat
     1561 aaatcatgga taaagttctt catcgaaccc gccaaaaatt ggctaatttt atttgggtta
     1621 aagtcaattc gcccttgccc ttcttgatat ttcaaaattt caatgtaagc aatattctca
     1681 tcatgcttat ccacaatttg ccaaccattt agaccaacag atttaacata accattattt
     1741 tcattcagtc gcattaactg ttcaaagtct aaaatcaata catcattttg cgtgtgataa
     1801 taaatattct ctttgagttt tccaacaatg gtaattcggt caattgacca ctgtatttta
     1861 aggggggtgg tcaaagtttg cacacttaac cgcctgttag atagggctgt taaattttcc
     1921 cactcattta tgatcgtgcc acgtttactc aaattttgtt cctcctcaaa gaaaaagaga
     1981 cttttggaaa gaatttccag agttcacgta accctaaaaa ttcatatcca aaaatctcta
     2041 gcttgaagaa acctaaaaat attcgtataa tgaacctgag ttacggagct aggtgaagta
     2101 gtttccgtaa atagtcgaga gtgttagcgc actgctcggc ttttattttg ctcttttttc
     2161 tcgttttctt tgattatagc actcctcct
//
LOCUS       DAFEEZ010000147         2082 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000147
VERSION     DAFEEZ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.156"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..1342
                     /locus_tag="LP245_002909"
     rRNA            <1..1342
                     /locus_tag="LP245_002909"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            1437..1552
                     /gene="rrf"
                     /locus_tag="LP245_002910"
     rRNA            1437..1552
                     /gene="rrf"
                     /locus_tag="LP245_002910"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            1566..1638
                     /locus_tag="LP245_002911"
     tRNA            1566..1638
                     /locus_tag="LP245_002911"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1599..1601,aa:Val,seq:tac)
     gene            1642..1714
                     /locus_tag="LP245_002912"
     tRNA            1642..1714
                     /locus_tag="LP245_002912"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1675..1677,aa:Lys,seq:ttt)
     gene            1722..1803
                     /locus_tag="LP245_002913"
     tRNA            1722..1803
                     /locus_tag="LP245_002913"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1756..1758,aa:Leu,seq:tag)
     gene            1821..1893
                     /locus_tag="LP245_002914"
     tRNA            1821..1893
                     /locus_tag="LP245_002914"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1854..1856,aa:Thr,seq:tgt)
     gene            1905..1976
                     /locus_tag="LP245_002915"
     tRNA            1905..1976
                     /locus_tag="LP245_002915"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1937..1939,aa:Gly,seq:gcc)
     gene            1993..2078
                     /locus_tag="LP245_002916"
     tRNA            1993..2078
                     /locus_tag="LP245_002916"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2027..2029,aa:Leu,seq:taa)
BASE COUNT          546 a          463 c          609 g          464 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc catttcttta agaaagtaag atccctgaga
     1261 gatgatcagg tagataggtc aggagtggaa gtacagtgat gtatggagcg gactgatact
     1321 aatcgatcga ggacttaacc aataggttaa aagaaaagaa ctcggaaaaa aacttatgtg
     1381 acttcaaatc cagttttgag tgaacaaaat ttactcaata aaagataaca ccacagtgtg
     1441 gtggcgatag cgagaaggat acacctgtaa ccatgccgaa cacagaagtt aagcttctta
     1501 gcgccgattg tagtgagggg ttgccccttg tgagagtagg acgtcgccac gcttaagtta
     1561 tccatggagg tttagctcag ctgggagagc atctgcctta caagcagagg gtcagcggtt
     1621 cgatcccgtt aacctccata tgagccgtta gctcagttgg tagagcatct gacttttaat
     1681 cagagggtca caggttcgag ccctgtacgg ctcatatttt tgcgggtgtg gcggaattgg
     1741 cagacgcact agatttagga tctagcgcct tacggcgtgg gggttcaagt cccttcaccc
     1801 gcataattta agttttacat gccggcttag ctcagttggt agagcatctg atttgtaatc
     1861 agagggtcga gggttcaagt cctttagccg gcatctttaa acacgcggaa atagctcagt
     1921 ggtagagcac caccttgcca aggtgggggt cgcgggttcg aaccccgttt tccgctttgc
     1981 caaagcaatc gcgccggggt ggcggaactg gcagacgcac aggacttaaa atcctgcggt
     2041 gagtgatcac cgtaccggtt cgattccggt cctcggcatt tc
//
LOCUS       DAFEEZ010000148         2021 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000148
VERSION     DAFEEZ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.157"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..449)
                     /locus_tag="LP245_002917"
     CDS             complement(<1..449)
                     /locus_tag="LP245_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1520754.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYLK"
     gene            793..1200
                     /locus_tag="LP245_002918"
     CDS             793..1200
                     /locus_tag="LP245_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520755.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            1214..1615
                     /locus_tag="LP245_002919"
     CDS             1214..1615
                     /locus_tag="LP245_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520756.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1617..1988
                     /locus_tag="LP245_002920"
     CDS             1617..1988
                     /locus_tag="LP245_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520757.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
BASE COUNT          716 a          283 c          330 g          692 t
ORIGIN      
        1 ttttttaaat atgcgttctc tgctcttaaa cgaataactt cttcttcaag agactcatct
       61 ttaagttttt taggaatgtt tagcttggaa ttcatactaa tttttctgcc ccttttttgg
      121 ctctcaagtg aagaagcacc gccttcttca tattgctcta tccatttact tagagttcta
      181 tttgaaccga tattaaattt tttagcagtt tcttggatag aaagaccatt tgtttccata
      241 tattctataa catcaagttt aaattttgta gtgtagcttt tgccacctcc aaccaagcct
      301 tcccaaccat gatagttata aatccttacc caatgtctaa ccagtgtacg atttatttga
      361 tatttatgtg caagatattt gtagccgcct tcgttattta aatagtctga aactactttt
      421 ttcttaaaaa caaatgtata tttccgcaaa aaaagcaccc cttttaatta gatttctagt
      481 ctaacttttg gggtgcacat catttttgag gggaagtaca tatagttgtt gatatagttg
      541 ctaatattgt tagctaattt gttagtaaaa ctgtatacga atttagatag taaaaaaaca
      601 gtttgttcct tatatagagg cacttttact actgattaaa tgtcagatat gcttacaaat
      661 atacttataa atatgcttac aaaattagct aatatttccg ttgacaaagc tttgttacta
      721 ttgttaaact aaattgacta gcaaaagtga aacataaatt tattaaataa atgtaaaaat
      781 taggagaaat caatgtctta tagagtacaa ttaataattt cagaagatgt agaaagtcag
      841 caatttggca ctaatgttat taataaagta attaatccag ctctttctat taatgcgcct
      901 ttaattccta ctgctttatc attttctgta acagctgtgg tgtctgagat agaggataca
      961 gaaaagataa aaatagtaga aattgaagtt ttaaacaaga atgaaaaaca aattttttct
     1021 acgggtgaag tatcggtaag cttgcctcct caagttaacg atataaactt taatataaac
     1081 gccagaaatg tcttggttga agaagcagga gagcattatg ctgttgttaa atttaatgga
     1141 actgagattg gaaggcaaat ctttgatatc aaggtcaaca aaccagtgga aaaaaattaa
     1201 ggagacgata cggatgcttg atatagtacc atcaaataca catcggagtg gtagcttaat
     1261 aaattttgct gcgatttttg cttgcgcatc ggtaattcta gcatctccag ttgttgtgga
     1321 tgcaagttct actccgaaaa ctaaaaatga taatcaactt gtaattacta caaaaaatga
     1381 gattaacaca atttcaagta atgatggcaa aatttttgat gtgataaata cggttttaaa
     1441 aagaaaagct gaaatcaata taaaatatga tgaagattta aacttgtatt tctttgttat
     1501 caaaacaaca tctgaattgt tttcctcaga ttacgatgtt ttggatactc tcgataatgt
     1561 attatctgac tataaatata tggggaaatc tgtagtagca actttggggg aataaaatgt
     1621 ttgactttaa tgaatattta tctatttcca aacaaattga atcagatgat aaatataatt
     1681 ctaaagaatc ttatagaaga actgctgttt caagagcata ctacagtgct tttaaaaaat
     1741 ctgatgagta tttgaaagaa aattatgata ttatttataa tggaagtagc ggaaaaggaa
     1801 gccaccaaac cgtttggaat ttgttttcaa cagttaagga attgaatacc ttaggaatac
     1861 ataatagtgg gtatagaatg ttagagaaaa gaaaatgtgc tgactatatt cctaatgaaa
     1921 ccattacgaa aacagatatg gcgctgatga atcgagaagc agaaaaaata ataaacaaac
     1981 tcacctaatg aatttcaagc gagtttgttt gttatttttt t
//
LOCUS       DAFEEZ010000149         1948 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000149
VERSION     DAFEEZ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.158"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            181..483
                     /locus_tag="LP245_002921"
     CDS             181..483
                     /locus_tag="LP245_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520758.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(999..1072)
                     /locus_tag="LP245_002922"
     tRNA            complement(999..1072)
                     /locus_tag="LP245_002922"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1036..1038),aa:Ile,seq:cat)
     gene            complement(1627..1941)
                     /locus_tag="LP245_002923"
     CDS             complement(1627..1941)
                     /locus_tag="LP245_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520759.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          708 a          289 c          301 g          650 t
ORIGIN      
        1 ttttataagg gtttgagcat tttttatttt cgcagatttt cgttaaatga atgaaaatgg
       61 cattcaaaat agcattcaaa aagaacactt tttaatatat atgttccatc catattatca
      121 atgatattcc tactttacaa aaagaacatt agttcgtata ctctttttga ggtgaacatt
      181 atgttgatgg aaggaaaaac acaattatgg tttaaatttg atccttcgaa tagatttgtc
      241 aaagattttt ataaggtgtg ggattcagaa gttttctttt tagcaatcga agatagctta
      301 ttaatcaatc tctattactc taataagaac tactttaaaa ttccggcaac aaaaaccaga
      361 atgaagaaag atgtgtattt tttgtttgat atcgtgactg atgtgccaga cgcacggagc
      421 gatcatcggc gttatgacta tttgaagtat actttcgttg atccagaaag gtataaagat
      481 taaagtaggc tacctaaaaa aggtagcccg gaacggattt tatcaccata cttataaaag
      541 ggatattttt taagttagta ttaagattgt gtaatatgat gatatctata ttttatagta
      601 tcagtgctat aaaatcaaaa ataagtcact aattaactac cactccaatt ataagtcttt
      661 ttcccattat tttttacagt tatatggtat gctttttaat ggcttcaaat ataaaagagt
      721 ttaaagcgta acacacttat ggggaagtgg tttttgggga acgctttaaa ctcttcttta
      781 ttattatctc acaatataac ccaaatgtct ttccatttaa aaatcaaagt aaaacttttc
      841 aaatatacag aagtataact atgtgaaaca tcctttcatt aatccataaa aggatacata
      901 aaaaagccac tcatttgagt ggcaatgaag aaaagcttta gcttgtataa tactcttcaa
      961 aaaattctaa cacagaacga ttcaattggc tacattaatg taccctgtag gactcgaacc
     1021 tacgaccgga cggttatgag ccgtctgctc tgaccaactg agctaagggt agtggttgtt
     1081 gccacataaa gccataaaca atcaaccagt agaatgcgtg gcaacaaacc tgttatcgca
     1141 tatcttggag tgtgactatt tatgagtgat agtgaagata tgcgtctcca tatatgtatg
     1201 gttgagacag ataaacatgt atgaaaaacg ttgttaaatc aacgtttttt tattttggtc
     1261 aaggagagaa aagtagagaa atacaaaatt ttttgcattg attttgcatt caaaaaaaca
     1321 ttcaaacatt tagaaatccc caatacgtat tcaggaaaat ctattttaag gtttacaaaa
     1381 agaacttttg ttcgtacact ctttttgagg tgaactttta tgctgatgga aggaaaaaca
     1441 caattatggt ttaagcatgt tccttcaaat aagtttttta attataaact ctagagaaat
     1501 taattcatcc taacataaaa taattgttca ctcaaaagtt tttctagaac aattaaaaca
     1561 gcaggcttca cattcgctat acatttgtaa gaagtaataa ttcctgtact aaaaggcata
     1621 attgctttaa ttattttttg acttctcttc aaacacaaga agtagttgtg taataattgc
     1681 agaaataagg attccaataa tagatataaa atttgacatg gaaacgtcta taacattaaa
     1741 agaataaagt gttgaagaaa gtaaactgat tgaaataacc cctccgtaaa aaatagtctg
     1801 tgaatatacc cacttttttt cagaagacgt acttcgtttg gttctaaaac ctatccctgc
     1861 atttctactc ttatcaaaaa accaaatatt tagaagtaat aatattgcta ttattaagat
     1921 aaaattactg taaaaatcca aaagctat
//
LOCUS       DAFEEZ010000150         1832 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.159, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000150
VERSION     DAFEEZ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.159"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..85)
                     /locus_tag="LP245_002924"
     CDS             complement(<1..85)
                     /locus_tag="LP245_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1520760.1"
                     /translation="MPRRQRRTYSKEFKQQIVDLYLAGKPCA"
     gene            360..902
                     /locus_tag="LP245_002925"
     CDS             360..902
                     /locus_tag="LP245_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520761.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            1058..1507
                     /locus_tag="LP245_002926"
     CDS             1058..1507
                     /locus_tag="LP245_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBL1520762.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDGMATLFLTKIIRCCECCGVMAPIALDNEHPRI"
     gene            complement(1537..>1832)
                     /locus_tag="LP245_002927"
     CDS             complement(1537..>1832)
                     /locus_tag="LP245_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1520763.1"
                     /translation="ILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQFETLA
                     QLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          668 a          270 c          352 g          542 t
ORIGIN      
        1 ctgcgcaagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt ggcatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcaa attgatgaag cagatcccaa
      181 agggctgctt catcaatttt ttcgtaagtg tccgtacact tactgtgctt gctcatatat
      241 taatcgatca tatactaatc gtgtaagaac aactttaagc ataatactta tattgttata
      301 ccatagtttg gaaaaataaa aaattatatt tcatcaacgt ttcataaaag gtgtgtagaa
      361 tgttattgaa agtagctata aaatgctatt gtgtaaaaaa taaaggagga ataatttatg
      421 aaaaaatagt accaagagga gcatgcctat tacttgcatt atgtttgagc ttaagcgcag
      481 ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga aggacaatcc ataagttctg
      541 aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga aacttttaag ccatcagatt
      601 atacattgga ggcaaagaaa gaatatgttt atgaatattt agggcttaaa tttaaactct
      661 cagacaaatt tagaaattat atagctgata aaaagatagc gatgttagat gatcaaagtc
      721 ctatagataa agaactaaag tatgctattt tgacatttga gaaaatgaca gaagaacaaa
      781 agaatgcagt tatagaaaag atgggcgatg gatataaaaa ttggcaaaat gagcttgaaa
      841 gaattgggac tattggtata tttgaaaaaa atacatcaga agaaaaaaat ctaaaattat
      901 aaaatgtgat actcatacta aaataggagt ttcaagtgat ggaaaatacg attgctattt
      961 aagcacaaat agcggagctg aaagtaatct tcttgatgaa ttaaaaagaa ctgagattca
     1021 aattatagat aaaaaagaac gtcctaaaaa tggttttgtg ctatcagaaa aaactgattt
     1081 agaaaataca gaagcattta acaaagaatc ggttaaagat ttacgtaaac taccaacaaa
     1141 ggacataaat ggcaaggatt ttacaagtaa agattttgag aagtatgatc ttactatggt
     1201 aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa attcctgatt tggttgaggt
     1261 tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga gttgttacag atcctgttga
     1321 tgataacggt gaaaacaagg aagcaattga aaagtcaaag ttaatacatg aaaagacaaa
     1381 ggcttcatat cctttcttaa tgccagatgg aatggcaaca ctttttttga caaaaattat
     1441 aaggtgttgt gaatgctgcg gtgttatggc tccgattgcc cttgacaatg agcatcctcg
     1501 gatctgattt tctccggcag aagcacaatc attcaattac gctgcctctc cagaggtatc
     1561 agatccgcgc tcattatcaa ggattcgctt cgccaatctc tgttgtcgaa tttggatcgg
     1621 tgtttcatac gccaacgtgc catgtaagcg tagatagttc caccaatgca cataatcaaa
     1681 caattctaga cgtagctgtg ccagtgtctc aaattggtat tgatgcacga attctacttt
     1741 gacagattta taggttgatt ccacaacggc attatcatac ggacaaccct tcctactcaa
     1801 tgaacgagta attccaaaac cattcagaat ct
//
LOCUS       DAFEEZ010000151         1750 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000151
VERSION     DAFEEZ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1750
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.160"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(190..567)
                     /locus_tag="LP245_002928"
     CDS             complement(190..567)
                     /locus_tag="LP245_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520764.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(867..1748)
                     /gene="galU"
                     /locus_tag="LP245_002929"
     CDS             complement(867..1748)
                     /gene="galU"
                     /locus_tag="LP245_002929"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBL1520765.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT          501 a          381 c          254 g          614 t
ORIGIN      
        1 acattggtat gatttatata tatataaata acataaaaaa aggaatggct tatcccgata
       61 caacaagcat tcctttaaaa aagattcttt tatataagtg aaaaaagctt ttttccacca
      121 attaaataaa tctctcatct caatagttta tccattattt tatctttttt tgcgtatacc
      181 tactaaatat taccgtcttc ttctcgttct tctactttgt tcgagagaat ctgtactaga
      241 aaaagtagtt gtatgtctac cttttctgcc tatccgagac tttcttttca tatatgggat
      301 ataaatgatt agatacagta cagcaaaaaa taaagcaaat acgcaagctt cccaactacc
      361 taacgccaat tcaaccatca aggtagcaac cccaacggat gctgcatacc agataaaaat
      421 cagaaacgtt tctttttttc tgaccatgcg aaacatgata aatagactaa taagcaatag
      481 tggcaacaca aatatccaat tgcttccttc catcagccac ttgagtatat caagcagcga
      541 ctgtgcaaca gcgactaatt ttcccatagt gaacacacac ctttttttat aattaaaaaa
      601 ttcgcctttt tattctacta tgaatcttct ggcttggctt tcatttctct tatgtaatca
      661 ttttctttta tacaacttaa aaaaaaatta aaccattagc ataatatttt ctgaatctat
      721 tcacgaaagt ctttttctat ctttcgtttt ccacgactca actgatctag agtcaaaaaa
      781 ctaaaacgac agttgcgcaa atgacgcaca agctgccgct ttaataacaa atagcctttc
      841 attctcagca ggccacttat ttccagttaa ctttctgttc ttagcttttt actcaactgg
      901 ataatatatg cacttaatga agtcccaatt tccgaatgtt gaagtccata ttcaatattt
      961 gtcttcatat atcctaactt atcgcctacg tcgtatcttt ttcctttaaa ctctctcgca
     1021 tagaccgcct ctgtctggtt aagagtctga agtgcatccg ttagctgtat ctcgtttcct
     1081 gctcctggtt cttgagtttc taatatctca aatattttag gagtcagtag ataacgtccg
     1141 ataatggcta aattacttgg tgcttttccc atttcaggtt tttctacaaa cccttttact
     1201 ctgcaacgac ccttttcgct atctgtttta ggatcaataa ttccgtattt agatgtttca
     1261 ttttctggta cacgcatgac ggcaacagcg gaagcttgtg tttcttcata atccatcatc
     1321 aattgttgag tcaatgggat atcatctttc atcaaatcat cccccagcat gacgacaaac
     1381 ggttcatttc ctataaatgc ttttgcttga agcacggcat cccccagtcc tcttggatga
     1441 gattgacgga tgaagtgaag attgacttga gtcgtttctt caactaaagc gagtaattct
     1501 gttttttcct tttcccgcaa attgttttcc aattcgatat ttgcatcaaa gtgatcttca
     1561 atgggtcttt tttcttttcc cgttacgatc aagatgtctt cgattcccga atccaatgct
     1621 tcttccacaa taaactggat cgttggttta tccacgattg gaagcatttc ttttgccatg
     1681 gcttttgttg ccggcaaaaa acgtgttcct agcccagcgg caggaatgac tgcttttttg
     1741 accttcactt
//
LOCUS       DAFEEZ010000152         1744 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000152
VERSION     DAFEEZ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.161"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            131..505
                     /locus_tag="LP245_002930"
     CDS             131..505
                     /locus_tag="LP245_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL1520766.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="LP245_002931"
     CDS             complement(619..1248)
                     /locus_tag="LP245_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL1520767.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="LP245_002932"
     tRNA            complement(1382..1454)
                     /locus_tag="LP245_002932"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="LP245_002933"
     tRNA            1668..1741
                     /locus_tag="LP245_002933"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
BASE COUNT          602 a          256 c          306 g          580 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaa
//
LOCUS       DAFEEZ010000153         1704 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.162, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000153
VERSION     DAFEEZ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.162"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..566
                     /locus_tag="LP245_002934"
     CDS             <1..566
                     /locus_tag="LP245_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL1520768.1"
                     /translation="ANVLDRTFTQEQPLEAIVTDLTYVRVGKKWHYICLILDLFNREI
                     IGYSCGEKKDASLVKEAFGRIPYSLTDVKLFHTDWGKEFDNQTIHEILNGFGITRSLS
                     RKGCPYDNAVAESTYKSVKVEFVHQYQFETLAQLRLELFDYVHWWNYLRLHGTLAYET
                     PIQIRQQRLAKRILDNERGSDTSGEAA"
     gene            672..887
                     /locus_tag="LP245_002935"
                     /pseudo
     CDS             672..887
                     /locus_tag="LP245_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1178..1657)
                     /locus_tag="LP245_002936"
     CDS             complement(1178..1657)
                     /locus_tag="LP245_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520769.1"
                     /translation="MCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNSL
                     DFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKGKKIKKCDKCFESAVVKFPQFKLNP
                     AASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQISSNLEDIKKAFKIKTIGTAPNFK"
BASE COUNT          565 a          274 c          279 g          586 t
ORIGIN      
        1 cagcgaatgt attagatcgg acctttacac aagaacagcc attggaagcc atcgttacgg
       61 atcttactta tgttcgcgtg gggaaaaagt ggcattatat ctgcttaata cttgatttgt
      121 ttaatcgaga aattattggt tattcctgtg gtgagaagaa agatgcctca ttggtaaaag
      181 aagcctttgg acggataccg tattctttaa cagacgtcaa gctttttcat acagactggg
      241 gaaaggaatt tgataaccaa accattcatg agattctgaa tggttttgga attactcgtt
      301 cattgagtag gaagggttgt ccgtatgata atgccgttgc ggaatcaacc tataaatctg
      361 tcaaagtaga attcgtgcat caataccaat ttgagacact ggcacagcta cgtctagaat
      421 tgtttgatta tgtgcattgg tggaactatc tacgcttaca tggcacgttg gcgtatgaaa
      481 caccgatcca aattcgacaa cagagattgg cgaagcgaat ccttgataat gagcgcggat
      541 ctgatacctc tggagaggca gcgtaattga atgattgtgc ttctgccgga gaaaatcaga
      601 tccgaggatg ctcattgtca agggcaatcg gagccataac accgcagcat tcacaacacc
      661 ttataatttt tgtcaaaaaa agtgttgcca ttccaaccaa tctaatcgag tctttcaata
      721 agcaaattaa aagatacagc cgtagaaaag agcagtttca aaatgaagaa tcactagaac
      781 gctttctagt cagcattttt gatacataca atcaaaaatt tctaaacaga agccataaag
      841 gttttcaaca ggtaaccgat acattagttt caatgtttac tgagtaacta attattttgc
      901 aggaggacaa tttatttaca caaaattatt gacgctccct taacaataaa tgaagacttt
      961 tttattgtta attgtttatt tttctattat tagatatgaa aatcgcattt agataaaata
     1021 gaaaaatatg aatatatttt aaatattaag atgagagtca ttaacttatg atagtagtca
     1081 atttgctttt cactaattac aaaatatgtg atataggaag tttagttatt gttctcataa
     1141 tgccatcctg tttttagatt atctagtaat ttttttgtta tttaaaatta ggagcagtgc
     1201 caattgtttt aattttaaag gcttttttta tatcttctaa attagaagat atttgtatat
     1261 caatatggaa tatattacct tttttgtatt tttttatgtt atctttagct aaaacatcaa
     1321 atacatgtcc ttgaaattgt atcgaggcag ctggatttag tttaaattga ggaaacttta
     1381 ccacagctga ttcaaaacac ttgtcacatt tttttatttt tttacctttg taaaaatatt
     1441 cgattgaata ttctatttgg cacgactcac ttggcagtat atgtatgtca atatttttca
     1501 tctgtttcat aggtatttca aaatctaaac tattaaaaac atataattcc ctgtaattat
     1561 ttacatctaa ctctactaaa tttatctttg gaacaataga tcctccaccc attccaccat
     1621 aataaaaaaa atcttgttct ctatcaaaat agcacatatt aagctcagtt tgtttatcat
     1681 cctcaataat tttataaatc aaac
//
LOCUS       DAFEEZ010000154         1679 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000154
VERSION     DAFEEZ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.163"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(365..1657)
                     /locus_tag="LP245_002937"
     CDS             complement(365..1657)
                     /locus_tag="LP245_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL1520770.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
BASE COUNT          516 a          343 c          284 g          536 t
ORIGIN      
        1 tatgggctac tctgtgatac ttattagcca ttaaactatt ttacccacat agcatatatt
       61 ttgaaatcgt tcattccgta aattcaacta aatatgccta aaaaaataaa aaatctaaga
      121 tagaataaga tttattcagt cttagatgga tttatagcaa ctttttcgta acaactttaa
      181 aaaatacgaa aagaaagagc tgttttactc tgactacgtt gctaaattgt cgtttaatca
      241 ttcatttaaa ccaaatcttt ttttatagaa ttcgttttaa tcctcctgaa tccaaaaact
      301 atgaaaaccg taattaaata gttaagagtt tttaaccacc ataattctct cggctatttt
      361 gaaatcagat aaattttgat cggacacata gttgaataaa cctaccgttg ttacggaagg
      421 taaatcgcat acttttcatt ctagaggaga aggtctcgtt gatcattaac tgattaagca
      481 ccatagccca gttttgaatt cgaccacctg accacttcgc gtgtaattct ttcgtgcgta
      541 aataaagtag ttttaggagt gcattctcat tagagaacgc tccttttttt gtgacttttc
      601 tgaagctgga gtggacactt tcaaccgcat tggtagtgta cataattttt cgaatggcac
      661 taccataatc aaatagttgt tcaacatgtg caaagttccg tttccagaca tctacagcac
      721 cagaataatg agaccaccga ttttgaaaac tgtcaaaagc agcatgtgca gcgtttagag
      781 aagaagcacc gtagaacttt ttcatatctc ggcagacttc cttatagtcc ttacttggaa
      841 tatagcgcaa tgcatttcga acaagatgaa caatacagcg ctgaacaatt accgatggaa
      901 agatcgcttt tgcgccttct tcgaggccag aaacaccgtc catcgaaatg aaaaagacat
      961 cttcgacacc acgtgctttc agttcatcaa atacttgcat ccagcgattt ttagattctg
     1021 tttgatttaa ccataatcct aaaatctcct tatttccttt gagatcatag ccaagaatgg
     1081 tgtatacagc atattctttg gcttcataat tttctcgtaa agtaacatac atacaatcaa
     1141 cgaatagaaa ggcataacac tttgctaggg ggcgggcttg ccattcttcc aattcaggaa
     1201 ggacagcgtc agtgatatct gaaatcattt catgggaaat atcaaagcca taaatagctt
     1261 cgacggttgc ggcaatatct cgttgactca ttcctcgtgc atacatggaa agaaccttcc
     1321 cttcgatgtc ggagacatct cgttttctct taggaattaa ctctggttca aaggaagctt
     1381 cccggtctct aggaacatca atagctactt caccaaaact ggttttaagc gttttagttc
     1441 catagccatt tcgacggtta tcgtgttcct taggctcttt agaatgggca tcataaccta
     1501 aatgattatt caattctcct tgaagcattt tttcaaaaag gggcccaaac acatctttca
     1561 aagcatcttg catgtcatcg acagattcag gttgataggc attcagaatg gattcagcta
     1621 acttttcggc atcaggattt cttttctttc tagccatcgt gtaatcacct cttgatctt
//
LOCUS       DAFEEZ010000155         1538 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.165, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000155
VERSION     DAFEEZ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.165"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..1307
                     /locus_tag="LP245_002938"
                     /note="aph(2'')-Ia"
     CDS             <1..1307
                     /locus_tag="LP245_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HBL1520771.1"
                     /translation="LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYP
                     KTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRA
                     YQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSI
                     EIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYS
                     YISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECT
                     IDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNH
                     LLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKA
                     KEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1437..>1538)
                     /locus_tag="LP245_002939"
     CDS             complement(1437..>1538)
                     /locus_tag="LP245_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1520772.1"
                     /translation="PNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          641 a          129 c          261 g          507 t
ORIGIN      
        1 cattaaaaaa acattataca gagccttggg aagatgaagt ttttagagta attattgaat
       61 ataacaatgt tcctattgga tatggacaaa tatataaaat gtatgatgag ttatatactg
      121 attatcatta tccaaaaact gatgagatag tctatggtat ggatcaattt ataggagagc
      181 caaattattg gagtaaagga attggtacaa gatatattaa attgattttt gaatttttga
      241 aaaaagaaag aaatgctaat gcagttattt tagaccctca taaaaataat ccaagagcaa
      301 taagggcata ccaaaaatct ggttttagaa ttattgaaga tttgccagaa catgaattac
      361 acgagggcaa aaaagaagat tgttatttaa tggaatatag atatgatgat aatgccacaa
      421 atgttaaggc aatgaaatat ttaattgagc attactttga taatttcaaa gtagatagta
      481 ttgaaataat cggtagtggt tatgatagtg tggcatattt agttaataat gaatacattt
      541 ttaaaacaaa atttagtact aataagaaaa aaggttatgc aaaagaaaaa gcaatatata
      601 attttttaaa tacaaattta gaaactaatg taaaaattcc taatattgaa tattcgtata
      661 ttagtgatga attatctata ctaggttata aagaaattaa aggaactttt ttaacaccag
      721 aaatttattc tactatgtca gaagaagaac aaaatttgtt aaaacgagat attgccagtt
      781 ttttaagaca aatgcacggt ttagattata cagatattag tgaatgtact attgataata
      841 aacaaaatgt attagaagag tatatattgt tgcgtgaaac tatttataat gatttaactg
      901 atatagaaaa agattatata gaaagtttta tggaaagact aaatgcaaca acagtttttg
      961 agggtaaaaa gtgtttatgc cataatgatt ttagttgtaa tcatctattg ttagatggca
     1021 ataatagatt aactggaata attgattttg gagattctgg aattatagat gaatattgtg
     1081 attttatata cttacttgaa gatagtgaag aagaaatagg aacaaatttt ggagaagata
     1141 tattaagaat gtatggaaat atagatattg agaaagcaaa agaatatcaa gatatagttg
     1201 aagaatatta tcctattgaa actattgttt atggaattaa aaatattaaa caggaattta
     1261 tcgaaaatgg tagaaaagaa atttataaaa ggacttataa agattgatta tataatatat
     1321 gaaaagctat tataaaagac attagtatta aatagtttaa aaaaatgaaa aataataaag
     1381 gaagtgagtc aagtccagac tcctgtgtaa aatgctatac aatgttttta ccatttctac
     1441 ttatcaaaat tgatgtattt tcttgaagaa taaatccatt catcatgtag gtccataaga
     1501 acggctccaa ttaagcgatt ggctgatgtt tgattggg
//
LOCUS       DAFEEZ010000156         1519 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.166, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000156
VERSION     DAFEEZ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.166"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(329..628)
                     /locus_tag="LP245_002940"
     CDS             complement(329..628)
                     /locus_tag="LP245_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520773.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(634..864)
                     /locus_tag="LP245_002941"
     CDS             complement(634..864)
                     /locus_tag="LP245_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520774.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(1114..1314)
                     /locus_tag="LP245_002942"
     CDS             complement(1114..1314)
                     /locus_tag="LP245_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL1520775.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          539 a          244 c          223 g          513 t
ORIGIN      
        1 aaagacattt gggttatatt gtgagataat aataaagaag agtttaaagc gttccccaaa
       61 aaccactgcc ccataagtgt gttacgcttt aaactctttt atatttgaag ccattaaaaa
      121 gcataccata tttttgaaaa aaagtgagaa aaaaggctta taattggagt ggtagttaat
      181 tagtgactta tttttgattt tatagcactg atactataaa atatagatat catcatatta
      241 cacaatctta atactaactt aaaaaatatc tcctttcata agtatggtga taaaatccgt
      301 tccgggctac ctttttaggt agcctacttt aatctttgta tctttctgga tcaacgaaag
      361 tatactttat atagtcataa cgccgatgat cgcttcgagc gtctagcaca tcagtcacga
      421 tatcaaacaa aaaatatacg tctttcttca ttctagtttt cgcagcaggg attttaaagt
      481 agttcttatt agaatagtag agattaatta ataagctatc ttcgattgct aaaaagaaaa
      541 cttctgaatc ccacacctta taaaaatctt tgacaaatct attcgaagga tcaaatttaa
      601 accataattg cgtctcatta aaaagcataa ccattactcc gatctatttt taaacttagt
      661 ctctacctct aatatatatc gagtttttat tttgccttca gagaatactg tttctttttt
      721 tgcagttaca ggttgtttat tttcggaaaa agctaatata gctaaaattg aaacatccat
      781 ctggaatttg tctttttcgt tgctttgctc ataaaaatct gcatattcat cactaatatt
      841 ttttctaata aattcttcca tcataaagat cacctcgaaa agagtatacg aacaaacgtt
      901 ctttttgtaa aggtggaatt tattatacta aataaatagg tgaacaagta cttgtgccaa
      961 attatgtgcc aaaaaaaatc gaatttaata aaacacaaac aaaaagaaat cctattatga
     1021 taacatttct tataataaca aacacaacag aagacgtgta atagttagtc aggaacgtac
     1081 aaataacccc tgtatccttt gcggtacagg gggttatttt gtataagtag acattgtagt
     1141 ttctaaactg ctatgtccta aacgtttcga tacgctaagt atatttactc cttgataaag
     1201 taaaatagat gcatgcgtat gtcttagtcc atcaataaac agtcgaagag aaaataggga
     1261 aaaattgatt actaaagaaa aacttactag gtcgacggtg tagttgattt tcatacttca
     1321 atagattcga attaaacgat ttcgattggc ttataccagt cctatccaac gaaagatata
     1381 tcgttcttaa ctctagcggt ataacttgaa gctttacgta aagccaatgg gaatgaactg
     1441 gagatgactt tttattattt ttagtaatag ctgatgggtt aatacttaca actttccttt
     1501 tcaaagtacc atataaaaa
//
LOCUS       DAFEEZ010000157         1500 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000157
VERSION     DAFEEZ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.167"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            316..570
                     /locus_tag="LP245_002943"
     CDS             316..570
                     /locus_tag="LP245_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1520776.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEDNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="LP245_002944"
     CDS             571..888
                     /locus_tag="LP245_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL1520777.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
BASE COUNT          531 a          228 c          290 g          451 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 gacaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaacctt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgacg taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt
     1261 taaaagagga agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa
     1321 aatatacttc cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa
     1381 aggaatggga taaaatatag gtacaataac tatttgatgc taaatataat taatggagga
     1441 gagatagtga acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt
//
LOCUS       DAFEEZ010000158         1457 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000158
VERSION     DAFEEZ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.168"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            109..1041
                     /locus_tag="LP245_002945"
     CDS             109..1041
                     /locus_tag="LP245_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBL1520778.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1113..>1457
                     /locus_tag="LP245_002946"
     CDS             1113..>1457
                     /locus_tag="LP245_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520779.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          640 a          169 c          228 g          420 t
ORIGIN      
        1 gatgaaataa atcaaaagta tgatgaaaca ttaaaaaatg tctattcttc acttatcgtt
       61 tcaaatatag aagaaacttc atcttctgaa ataaaaaata agctttcttt gttaaaatta
      121 aaagaaaagg aatatattat tgacgatgct gtttctgtcc ctcttatttt aaataaacga
      181 gagaaaaata atttaaagaa aaaaatgctc attccatttg attcagaagt gaaaggatta
      241 ctcaataaac taactatttc taatatagac tcgactaggg aaaaaatcat aaaaatattt
      301 gataaaatta ataatttatt caagaatgac aatgctgaat taaggaaggg tcttttagag
      361 tttaaacttc aagaactaga acttcattac tcttatttag tgaaaattac cgaagaaaaa
      421 gaacaacaaa aagcaataaa agaacagatg atagaagagg aaaaagttcg tagagaaatt
      481 gatcgtgaaa agaaacgtat tgataaagaa caacgtcaat tcaattctga aatttccaaa
      541 ttaatcgcat atatgcaaaa agctaatgca gatgtggaaa aagaattata tgcaaataaa
      601 attcaagaac tggaagaaaa attaaaagaa ttagaagtta tacgtgaaaa tgtattacaa
      661 agagaattaa atactagagc cggttatgtg tatgtaatta gtaatattgg gtcttttggt
      721 gaagacatat ataaaattgg tatgactaga agattagaac ctatggatag aataaaagaa
      781 ttgagtagtg catcggttcc atttgaattt gacgttcatg cgatgatttt ttcagaggac
      841 gctccgtctt tggaaactaa attgcataat cattttagaa aacaagaagt taataaaatt
      901 aatcaaagaa aagaattttt caaagtttca ctagacgaaa tagagaaagt tgttttagaa
      961 aattataatg gaacagtaac atttacaaaa ttagctaaag ctgaacaata tagacgatct
     1021 ttagaattgt caaaagatta aatatataaa aagccttcgg gctttttctt ttaacaatta
     1081 ataggaacgt atattcgaaa ggaatagaaa taatgtggtt agaaaaaata aatgacaaaa
     1141 aatttaagta caccgaacgt tatacggatc ccttaactga aaaaaagaga aaagtgtccg
     1201 ttactttatc tagcaattca cgccaagctt ggaatcaagc taacttactt ttgaatgaaa
     1261 aaatcgcaga aaaaataaaa cgaaatgaag aattaccact aacttttgga gaattaaaaa
     1321 ctaaatggga tgaaaaatac aagccaactg taaaagaaag ttcctatcga acaactcagg
     1381 tttatctatc attaatttca aaatatataa aagatgatgt acttgtaaaa aacgttaata
     1441 gtaatcttat acaagat
//
LOCUS       DAFEEZ010000159         1424 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000159
VERSION     DAFEEZ010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.169"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(150..1337)
                     /locus_tag="LP245_002947"
     CDS             complement(150..1337)
                     /locus_tag="LP245_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBL1520780.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAFEEZ010000160         1375 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000160
VERSION     DAFEEZ010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.170"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..296
                     /locus_tag="LP245_002948"
     CDS             <1..296
                     /locus_tag="LP245_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBL1520781.1"
                     /translation="KVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSNDELFKD
                     SVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDVK"
     gene            293..523
                     /locus_tag="LP245_002949"
     CDS             293..523
                     /locus_tag="LP245_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520782.1"
                     /translation="MKYEIPLSEAGIQAIINGREVNIELPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSIDNTFRLGS"
     gene            530..733
                     /locus_tag="LP245_002950"
     CDS             530..733
                     /locus_tag="LP245_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBL1520783.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASDAIRKFGISILNDDRKWEEMR"
     gene            730..1029
                     /locus_tag="LP245_002951"
     CDS             730..1029
                     /locus_tag="LP245_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520784.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMEVINNEV"
     gene            1019..1183
                     /locus_tag="LP245_002952"
     CDS             1019..1183
                     /locus_tag="LP245_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520785.1"
                     /translation="MKFKIFEEDTRYKLEKELNDFAKNNEIQHISLATSKRGYANYYA
                     AVVSYVSREV"
     gene            1272..>1375
                     /locus_tag="LP245_002953"
     CDS             1272..>1375
                     /locus_tag="LP245_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBL1520786.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSL"
BASE COUNT          497 a          201 c          331 g          346 t
ORIGIN      
        1 caaaagtaga gcagtgggct aaagacaagg gactggatca agcagatcca aaagcacagt
       61 ttttgaaagt agctgaggaa ttcggggaaa tagcttcggc gatggcaaga agtaatgatg
      121 aactatttaa agatagcgta ggagacgtta tcgtcacgct gattatcctt tccatgcaaa
      181 aagggacaaa cgtacaagag tgtttagaaa tggcatacaa cgaaatcaaa ggacgcacag
      241 ggaaaatggt agatggtgta ttcgtgaagt cgagtgattt ggaggatgtg aaatgaaata
      301 cgaaatacca ctaagtgaag cgggcattca agcaattatc aatggtcggg aggttaacat
      361 agaacttcct gatggtactg aattagtcat cagacaaagt tatttgaaag atatggcagc
      421 tccagtatta attgatcgtt ttaacgtgac tgattctgtg gtagagaacc acttaaaaga
      481 atttcgatca agtatagaca acactttcag attagggagt tgattgacaa tgaacaccag
      541 acaccgcaga gtagcaaaac taagaaaaca ggaactaaat gtactaaaga caaagtttga
      601 aaaagaatat ggaatttcag cagaagaaac atataaagtg gcaagtcagt ttgttgctga
      661 tgcaagtgat gctattcgta agtttgggat ttcgatatta aatgatgatc gtaaatggga
      721 ggaaatgaga tgaaactaaa agacggattt tacgctagta gtcacggcat cggcggttta
      781 atgctagata tgccgacaaa gaaccctaaa acacgtaaga aaccaaaagt caaagtcggt
      841 gacatggttc gctgtgaagc agaagagttc atttatccgt ttcgtggata tgtagaacac
      901 gtctataatc actcagcgat cattcgtatt gaaaacacaa tggaatgcga taagtggtta
      961 gcgaaaagca aagagaattt agctgtagcg agattggtgg atatggaggt tataaacaat
     1021 gaagtttaaa atctttgaag aggacactcg ttataaatta gaaaaagaat taaacgattt
     1081 tgcgaaaaac aatgagattc agcatatatc tttagcaact tctaagagag gttatgcaaa
     1141 ttactatgca gctgttgtga gctatgtaag tcgagaagtg taactcggca aataaaaaaa
     1201 gccggatcgc tccgactgat tcaataaatc caacacattt attatatcac ataaaggagc
     1261 ggtttgactt gatgcaattg ttacgagagg tagatttcaa acagacaaga tgtaatgcga
     1321 gagatgtgct gaagaacttt cggcgtttgg agcggatggc aggtcgctct ttgat
//
LOCUS       DAFEEZ010000161         1360 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.171, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000161
VERSION     DAFEEZ010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.171"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            82..>1360
                     /locus_tag="LP245_002954"
     CDS             82..>1360
                     /locus_tag="LP245_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HBL1520787.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQ"
BASE COUNT          461 a          255 c          259 g          385 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg
      421 aatcatgtca gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaaatt gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc
      541 tacttaccaa agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt
      601 tcgcacgctt ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa
      661 ttaattgatg tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc
      721 gctaatcctg aagaagtaaa atttttagtc acagacatga acgccgccta cttccagctt
      781 accaaacgta ttctgccaaa tgcgaaagta gtgattgatc ggtttcatat tatcaaacac
      841 atgaatcaag cctttaatga gttgcgtatc cgtgaaatga atgaacttcg taaagtagga
      901 cagaaaagtc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagttttc gagcaccaaa atacccattt
     1021 cttacggaag cgatgatgat tgatcgattg cttggctttt ctacgtccct gaaggaggcg
     1081 tatccctatt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacggct ttcgggaaaa gctccaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcgatgatct atccttacac caatggaaaa
     1261 atagaagcga agaataccca tataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat
//
LOCUS       DAFEEZ010000162         1312 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000162
VERSION     DAFEEZ010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.172"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            82..>1312
                     /locus_tag="LP245_002955"
     CDS             82..>1312
                     /locus_tag="LP245_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBL1520788.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYG"
BASE COUNT          444 a          257 c          251 g          360 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg at
//
LOCUS       DAFEEZ010000163         1294 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000163
VERSION     DAFEEZ010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.173"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..1244
                     /locus_tag="LP245_002956"
     CDS             <1..1244
                     /locus_tag="LP245_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBL1520789.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          423 a          233 c          277 g          361 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaaaacgc caaacattcc
     1261 cgattctatt ctataggtcg ggttatttga cgta
//
LOCUS       DAFEEZ010000164         1292 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000164
VERSION     DAFEEZ010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.174"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            141..398
                     /locus_tag="LP245_002957"
     CDS             141..398
                     /locus_tag="LP245_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520790.1"
                     /translation="MSKLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="LP245_002958"
     CDS             complement(630..1061)
                     /locus_tag="LP245_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HBL1520791.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          489 a          167 c          161 g          475 t
ORIGIN      
        1 ttctgtccac gttcatatta ctccaaagtt ttcctcattc caaaagaaaa gcacagaata
       61 cacaaagaag cgtttttatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaaat tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 acaaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatccc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca cacataaaaa taaaaaacat
     1141 ttgtatttta tcaaagtttt attatacttg tcaatttgtg tacatcctaa aatataagct
     1201 atttgtttac ttctgtagaa tatatacttt gttgttagat aagttgcaca tgtttataga
     1261 atctaaataa taaattttta tgtaccgccc ct
//
LOCUS       DAFEEZ010000165         1177 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000165
VERSION     DAFEEZ010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.175"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..1143
                     /locus_tag="LP245_002959"
     CDS             <1..1143
                     /locus_tag="LP245_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL1520792.1"
                     /translation="NHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYF
                     TANTYIVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKV
                     KRNWLPRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERR
                     ARLKVKVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRN
                     DPTQAKYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELR
                     IAYFYYQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPY
                     SNAKIENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          378 a          239 c          219 g          341 t
ORIGIN      
        1 aatcatgaag gcatgatcgt taagaacgga aagaaaaaat cgctcattca acttaataaa
       61 tgtgcgaacc aactgactta tcttgcttta gcgaaacaac gctaccactg tcgtggctgc
      121 cacacctatt ttacggcgaa tacctacatt gtcgatagaa actgctttat cgctaaacaa
      181 gtgcgctata aaattttaga agagctaact gaaaaacaag caatgacgac aattgctaag
      241 cattgcggcg tttcttggtc gaccgtttct cggacactcg cttctctgat ccccatgaca
      301 aaagtaaaaa gaaattggtt accgcgttgt ttattaatgg atgaatttcg ttcactgaaa
      361 aatcaagtcg gtccctactc cttttcttgt atggatggcg atactggaaa attactggat
      421 attcttcctt cacggaagaa aaaggctctc gtttcttatt ttatgcaatt tgaacgacgc
      481 gcacgattga aggtaaaggt catcgtgacg gacatgaatg tttcttatgc ctctctgata
      541 aaggaatgtt ttccaaaggc aaaactcgtt gtggatcgtt ttcacattgt caaacatctc
      601 attcgtaaat ttgaggatat tcgcgtacga atcatgaaaa gctttgatcg aaacgatcca
      661 acacaagcca aatattatcg acaattaaag gcgttgtctc ggcttctgat caaacgacag
      721 gacaagcttg tttatgacaa atggaccaaa tggcgcaatt ttggttgggc gtatctcacc
      781 gaaagtgaag tggtggatcg tctgctttcg atctctgacg aattacgaat cgcctatttt
      841 tactatcaag aaattcttca agcgtttcac gacaaagagg cggacacttt ctttaaactt
      901 gtaagaacga tgcccaattc cgttccaaaa gaactgcatt ctataaaaaa agcttttata
      961 aactatgaat ccggcattcg tttagccctc gaattgcctt attcaaatgc caaaatagaa
     1021 aatctgcata cccacatcaa agcattgaaa cgagtcgctt atggctttcg aagctttcgg
     1081 aaaatgaaga ccagaatttt cttactaaat aatctgatta cctatgaatc aaaaaacatc
     1141 taaagtagaa aaggaattct accttagatg ttcttat
//
LOCUS       DAFEEZ010000166         1124 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000166
VERSION     DAFEEZ010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1124
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.176"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            96..>1124
                     /locus_tag="LP245_002960"
     CDS             96..>1124
                     /locus_tag="LP245_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL1520793.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAV"
BASE COUNT          357 a          229 c          209 g          329 t
ORIGIN      
        1 accagcatct tttttatttt ccaaaacata tagaaaagac accttgaaat cctttagaat
       61 taatttggcg aaccaaccca aaaggaggaa tcaagatgtc ttacactcac cttatcaaag
      121 aaacattaga tattctagac ttatcagtta cttttaacga aaattgtctc acaaaagaaa
      181 aatacaaagg gcaaatctgt catatttatc gtggaaactt gatttataca gcccaagaat
      241 gcatccactg taaacaccag attgcttcag atattgtgcg ttggggtaca acaaccgtcc
      301 ggttgttaat gaacgatgtt tctgaatacc gtacctacct cgaattgaaa aagcaacgct
      361 tcaaatgcaa agcttgtcag cggacctttg tcgcagatac ttctgttgcg aaaaaacatt
      421 gtttcatcag tgagaaagtc cgctggtctg tcgtgactcg tctgaaaaaa aatacctcaa
      481 tgacagagat cgccgctcag aaaaatctat cggtctcttc tgtttaccgt attatgaagc
      541 gattttatcg tccgttgaat ccttttcgga caccgttacc taaggtactt tgttttgatg
      601 aattcaaatc agttcggggt gtttcaggtg ctatgagttt catcatgatg gatggacaaa
      661 cacagcgctt attggacatt gtcgagaacc gacaactgcc ttttttaaaa cgttatttta
      721 gtcatttttc acgagaaatt cgtgaagcgg tcgaatggat cgtgattgat atgtacgctc
      781 cttatgtatc gctcgttaaa aagctgtttc caaaagcaca gctgattatt gaccggtttc
      841 acatcgtcca acatattggt cgtacctttc gcaatcatcg aatcaaagaa acgaaccaac
      901 tattaaaaag caaagaacaa aaacactatc aattaggtaa gcaattaaaa agatactgga
      961 aacttcttca aaaagatgaa cgcaagcttg attatactcg acgcctttgg cgacctggct
     1021 tcaaagctca tttaacagag accgatattg tggatcgctt actgaaaggg agccctgctt
     1081 tgcgtgtagg ctatcagtta tatcaagact ttctttacgc tgta
//
LOCUS       DAFEEZ010000167         1089 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000167
VERSION     DAFEEZ010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1089
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.177"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            41..>1089
                     /locus_tag="LP245_002961"
     CDS             41..>1089
                     /locus_tag="LP245_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HBL1520794.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRR"
BASE COUNT          405 a          202 c          198 g          284 t
ORIGIN      
        1 atgtttttaa cgacaaaaac atacccagga ggacttttac atgacccaag tacattttac
       61 actgaaaagc gaagagattc aaagcattat tgaatattct gtaaaggatg acgtttctaa
      121 aaatatttta acaacggtat ttaatcaact aatggaaaat caacgaacag aatatattca
      181 agcaaaagaa tatgaacgaa cagaaaaccg acaaagtcaa cgaaatggct attatgagcg
      241 cagctttacg acacgtgtag gcacgctaga attaaaagta cccagaacac gtgatggcca
      301 tttttcaccc acagtgtttg aacgttatca acgaaacgaa aaagccctca tggcttcaat
      361 gttggaaatg tatgtatcag gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact
      421 ttgtggtaaa tccgtctcta agtccttcgt ttctagctta acagaacagc tagaacctat
      481 ggttaacgag tggcagaatc gtttattatc agaaaaaaat tatccttact taatgaccga
      541 tgtactctat ataaaagtac gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc
      601 gattggaata accaaagatg gcgaccgtga aattatcggc ttcatgattc aaagtggcga
      661 aagcgaagag acctggacaa cattttttga atacctaaaa gaacgcggtt tacaaggtac
      721 ggaactcgtt atttctgatg cgcacaaagg attagtctct gccattagaa aatccttcac
      781 caacgtaagt tggcaaagat gccaagttca cttcctaaga aatatcttta ccaccattcc
      841 taaaaaaaat tcaaaatctt tcagagaagc tgttaaagga atttttaagt tcacagatat
      901 taacttagcg cgtgaggcta aaaatcgatt gattcatgat tatatcgatc aaccaaaata
      961 ttcaaaagct tgcgcatcat tggatgatgg attcgaagac gcctttcaat ataccgtaca
     1021 aggaaattcc cacaatcgac taaagagtac caatctaatt gaacgactga atcaagaagt
     1081 acgcagaag
//
LOCUS       DAFEEZ010000168         1058 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000168
VERSION     DAFEEZ010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.178"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(36..992)
                     /locus_tag="LP245_002962"
     CDS             complement(36..992)
                     /locus_tag="LP245_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520795.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgt
//
LOCUS       DAFEEZ010000169         1045 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000169
VERSION     DAFEEZ010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.179"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..203
                     /locus_tag="LP245_002963"
     CDS             <1..203
                     /locus_tag="LP245_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL1520796.1"
                     /translation="IYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQK
                     FLNRSHKGFQQVTDTLVSMFTE"
     gene            256..1038
                     /locus_tag="LP245_002964"
                     /pseudo
     CDS             256..1038
                     /locus_tag="LP245_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
BASE COUNT          438 a          154 c          137 g          316 t
ORIGIN      
        1 ccatttactc aaccaatcta atcgagtctt tcaataagca aattaaaaga tacagccgta
       61 gaaaagagca gtttcaaaat gaagaatcac tagaacgctt tctagtcagc atttttgata
      121 catacaatca aaaatttcta aacagaagcc ataaaggttt tcaacaggta accgatacat
      181 tagtttcaat gtttactgag taactaatta ttttgcagga ggacaattta tttacacaaa
      241 attattgacg ctccccaaga tatgctagat tactactatt ttgaaaaaaa tttatcatat
      301 aattatgtaa tacatttaaa aacttttaca ggaatgattt ttaaattcgc caaccgtcga
      361 tatggattaa aatataatcc cgtaaatggg gtttctttag caagaaaacc taagacaaac
      421 gaagaaataa aaaaagaaaa agatggttat ttatcaaaag aagaagttca aatgattgct
      481 agtaaacaaa aaagttcaca tcaacagtca cgttattctt taattactaa atttttgttt
      541 ttaactggac tacgttatgg tgaattgata tctttgactg aatctgatta tgatggtaat
      601 aaaattacgg tttctggtac ttatgattac gagttaaaaa ttaaaacaac aactaaaaat
      661 acaggttctt atagaaccat tgaattatca agtaatgcta aagaaatcat agatcaatta
      721 attgaagaaa acaaattaat taagaataat aaagataaat acattttcat ctctaaaaat
      781 ggtaacccga tatctattca agcatataat caatctttaa gagcagtatc caaagaatta
      841 aacatagata aaaaagtttc ttctcacatg ttaaggcatt cccacatttc tctacttaca
      901 gaattaggaa tcccattaaa agccattatg gatcgtgtag gacatgaaga ttcaaaaaca
      961 acattaaaga tttatactca tacaactaaa aatatgcaaa atcaactagt agaaaaacta
     1021 ggaaaaatag aaatttaaat tgccc
//
LOCUS       DAFEEZ010000170         1030 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.180, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000170
VERSION     DAFEEZ010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1030
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.180"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..931
                     /locus_tag="LP245_002965"
     CDS             <1..931
                     /locus_tag="LP245_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBL1520797.1"
                     /translation="EFNLGANEGSSQVANNQYILLHETANETATGRNEAQYMQRSWTS
                     AYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKATFEKNYKAYVE
                     LARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYD
                     LAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIENANLHVAGWHI
                     ANYKYEYIFIMDYNTGKELARVRADGIYRSDVNQAYNTSGNVGYHVSFNMRNFPNKKV
                     YVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          354 a          187 c          209 g          280 t
ORIGIN      
        1 tgaatttaat ttgggcgcaa atgaaggtag ctcacaagta gcaaataatc agtatatttt
       61 actgcatgaa acggctaatg aaacagcaac aggacgcaat gaagcgcagt atatgcaacg
      121 ttcatggact agcgcttata ctgcttatat tgtgggagac ggcggaattg tttatcaagt
      181 cggtcaacct ggttatgtac agtacggtgc tggttcgtat gctaatgcca acagtcctgt
      241 gcagattgag ttacaacaca cacatgataa agcaacgttt gagaaaaact acaaggcata
      301 cgttgaattg gctagagatt cagcaatgaa atatggtatt ccattaacgt tggacactcc
      361 ttataaccaa ccgggaatca aatcgcattt atgggtaaca caaaacatct ggggcgatca
      421 tacagatcct tacggttatc tttctgaaat gggcgtaagt aaagaaaaat tagcatatga
      481 tttagctcat ggatttaccg atgaaaatcc aacaacttct gaaaacaagc ctgtcattga
      541 tccaacacga gctggtgcag ctaatcctac actgacagat ggaacgaatt acgcccacat
      601 tgatcagttt ggagaaatcg aaaatgcaaa tttgcatgta gctggatggc acattgctaa
      661 ctataaatac gagtatatct tcattatgga ttacaatact gggaaagaat tagctcgagt
      721 aagagctgat ggaatttata gatcagatgt aaatcaagct tataatactt ctggaaatgt
      781 tggctatcat gtatctttta acatgcgtaa cttccctaat aagaaagtct atgtcatgat
      841 gcgggcaacg aatgatccag agggaaacac taaaggcggt gcgcaagatt tccatgacaa
      901 acgttggtat ttaaatattc ctaaacgata aaaatagctc ctcgttgagg agcattacat
      961 aactatattg acaactataa aaatcattcg ataaaatagt gatgttatcg catatcttca
     1021 ctatcaccca
//
LOCUS       DAFEEZ010000171         1009 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.181, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000171
VERSION     DAFEEZ010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.181"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            36..995
                     /locus_tag="LP245_002966"
     CDS             36..995
                     /locus_tag="LP245_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1520798.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
BASE COUNT          364 a          180 c          192 g          273 t
ORIGIN      
        1 agttccgacg aaagaattat aaggagtgag tacaaatgac ctataaccat cttacaccaa
       61 ctgaactcgt aatgatagaa gcttatttca atcaatcaca acctgtttca aaagtagcca
      121 atctgttaca acgttctcga caaactattt ataaggtcta tcgttttctt aaatctggtg
      181 gaagcgcaat gagctactat aaacaatata agaaaaacaa acgtaactgc ggaagacatc
      241 cgattgtttt acctgatgag caacaggaat acattcaaaa aaaggttgtt caagggtggg
      301 ctcctgatgt ccttattggt cgagcagagt ttcctattgc ttgttcggta cgcacactgt
      361 atcgaatgtt taaagataaa acctttgaca ctcacgattt accaatgaag ggaaaaagaa
      421 aaccaaacgg tcataaagaa aaaagaggaa aacaagggtt tcgccggtca atccgagaca
      481 gaaagacaga ctatacccag tttgatcatg aatttggtca cctggaaggt gacactatcg
      541 tgggtggaaa acataaaagc gcggtcatca cattagttga acggctatct aaagtcatca
      601 ttaccttgaa acccgaaggc agacaggcta aagacattga aaataggctg aatcaatggt
      661 ttcgttgtgt cccaaaaaac ttatttaaat ccatcacatt tgattgtgga aaagaattct
      721 caaattggaa aaagattagt aataccaacg atatttcaat ttattttgcg gatccaggaa
      781 caccttctca acgaggattg aatgaacatt caaatggctt attacgtaaa gatggtttgt
      841 ataaagctat ggattttaat ggtgtatctg aaacctttat ccaatcggtg gcatcgaaac
      901 gaaatcatat tcctagaaaa tcattacact atcggacacc aatggaagta tttttgagtt
      961 acgtcacaaa agatgatttg tctaacttaa tttgacaaac gaaaaaagt
//
LOCUS       DAFEEZ010000172         1000 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000172
VERSION     DAFEEZ010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.182"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            369..1000
                     /locus_tag="LP245_002967"
                     /pseudo
     CDS             369..1000
                     /locus_tag="LP245_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          343 a          181 c          183 g          293 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgaagaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DAFEEZ010000173          986 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000173
VERSION     DAFEEZ010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.183"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            33..>986
                     /locus_tag="LP245_002968"
     CDS             33..>986
                     /locus_tag="LP245_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HBL1520799.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRG
                     VQEVLLFITDGLKGMKDTIHQIYPKAKYQHCCIHVSRNIAHKVRVKDRKEICDDFKAV
                     YQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDLLTFYD"
BASE COUNT          359 a          184 c          170 g          273 t
ORIGIN      
        1 gacaaccaat tcacagaaaa gaggacttcc ctatgaatga ttttactaca gaaattgtgc
       61 aaactctagt cactaaaggc gatttaaatg aattattccg ttcgcactta gaaaaagcga
      121 taaacacact cctacggact gaattaacgg cttttttaga ttacgaaaaa tatgatcgca
      181 ctggttttaa ttcaggtaat tcgagaaacg gttcttactt tcgatcaatc aaaaccgaat
      241 atggtgaatt aacattggaa atacctagag atcgtaatgg tgagtttaaa caacaaactt
      301 taccagccta caaaagaaca aacgatacat tggaaaccac tattatccat ttattcgaaa
      361 aaggtgttac gatgtctgaa attgctgatt tgatcgaaaa aatgtacggt catcactata
      421 ctccacaaac catgtccaac atgactaaag ttctgactga agaagtaaat gcctttaaat
      481 ccagagcctt aaatgataag tatgtcgcta tttttatgga cgctacttac attccactaa
      541 aacgtcaaac cgtatccaaa gaagcgattt atattgccat tggtatacga gaagacggca
      601 ctaaagaagt actgagttat gcgattgctc caactgaatc aacatacgtt tggaatgagc
      661 tgctacagga tattaactcc agaggagttc aagaagtctt gctttttatt acggacggct
      721 taaaaggcat gaaagatact atccatcaaa tttatcctaa agcaaaatat cagcattgtt
      781 gtatccatgt atctcgtaac atcgctcata aagtacgtgt caaagaccga aaagaaatct
      841 gtgatgactt taaggctgtt tatcaagcta actcaaaaga agaagcgaat accttcttat
      901 ccggcatgat tgagaaatgg aagaaaaact atcctaaagt gacgcagtca ctcatagaaa
      961 accaagactt attaactttt tatgat
//
LOCUS       DAFEEZ010000174          943 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000174
VERSION     DAFEEZ010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.184"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..>943
                     /locus_tag="LP245_002969"
     rRNA            <1..>943
                     /locus_tag="LP245_002969"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DAFEEZ010000175          935 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000175
VERSION     DAFEEZ010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.185"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..818
                     /locus_tag="LP245_002970"
     CDS             <1..818
                     /locus_tag="LP245_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL1520800.1"
                     /translation="TRYQLIKQLIRTKQHFLENLTYKCNTLAREMRDESTSLFSATLI
                     SLMTEDFTLDELAELPLEAFCDLLQEKGKGRFKQPEKIAKAIQRAITMSYRLGALAQE
                     SINVVLSVLVREIRALEKNIKELDKAIEQVIVVIPEYQCLTSIPGVGKVYAAGLIAEI
                     GQIERFEDQTKLAKYAGLSWKVNQSGNYQSQNTPLTKQGNRYFRYYLVEAANSVKNYL
                     PEYKAFYQSKYKEVPKHQHKRALVLTARKFTRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          334 a          182 c          163 g          256 t
ORIGIN      
        1 gtactcgcta tcaacttatt aagcaattga ttcgtacaaa gcaacatttt cttgaaaatc
       61 taacgtacaa atgtaatacg cttgctcgag aaatgcgaga cgaatcgacg agtcttttta
      121 gtgcaaccct catttcactc atgacggaag atttcacatt ggatgaactt gctgagcttc
      181 ctttagaagc tttctgtgat ttacttcaag aaaaaggaaa aggccgtttc aagcaaccag
      241 aaaaaatcgc taaagcaatt caacgtgcaa ttaccatgag ttaccgccta ggtgctcttg
      301 cacaagaatc aattaatgtt gttttaagtg ttctcgtacg agaaatacga gcacttgaaa
      361 aaaatatcaa agaattagat aaagccatcg aacaagtaat tgttgtcatt ccagaatatc
      421 aatgcttaac cagtattcca ggcgttggta aagtctatgc tgccggttta atcgctgaaa
      481 ttggtcaaat cgaaagattt gaagatcaga caaaattggc aaaatacgct ggattaagtt
      541 ggaaagtgaa ccaatctgga aactatcagt cgcaaaatac acctctgaca aaacaaggaa
      601 atcgatattt tagatactac ttagttgaag ctgccaactc tgtaaaaaat tatcttcctg
      661 aatacaaagc tttttatcaa agtaaatata aggaggttcc aaagcatcaa cacaaacgtg
      721 cactcgtcct aaccgcaaga aaatttacgc gtctggtgga tacgctacta cgtaaacacc
      781 aactctatac gccaccaagg agtgtgatag agaaataaca atccgttatt gacgcaaatc
      841 cttgaatcaa cccgaaaaaa atttgatttt gatcgggtct agtttcgtgc gcttcaaaac
      901 atattactca ataaagaaaa tcttaaattt catct
//
LOCUS       DAFEEZ010000176          910 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000176
VERSION     DAFEEZ010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..910
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.186"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            25..708
                     /locus_tag="LP245_002971"
     CDS             25..708
                     /locus_tag="LP245_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL1520801.1"
                     /translation="MDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYLLTGQTEMAIR
                     EQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAKERGIHTIVAS
                     SNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNIPPSEALVFED
                     SIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADYEFYDLHQAKR
                     FLESKGLYL"
BASE COUNT          336 a          129 c          186 g          259 t
ORIGIN      
        1 aaaatcaagc tcttcatctt tgatatggat ggccttttat tagaaactgg acgtttagct
       61 tatcgtgctt atgtaaaatc agcacaaaag tatgattatg aaatgcgtaa ggaagtctat
      121 tatttactaa ctggccaaac agaaatggcg ataagagaac aaatgggcat tttgtacgga
      181 gaagatgttc catatatcaa atggcgagaa gcaatcaatc aatataaaga aaaaatcgtg
      241 aaagaagata agagagtata tacgaaaaaa ggagcagaag aaattttatc ttttgcaaaa
      301 gaaagaggaa tccatacaat cgtggcttcg tctaatacac gggtaaaagt agaaatgtat
      361 ttaaaaatgg aaaatctata tgccttgttt gatcaaatca tttcagggga tgatgtaaaa
      421 aaaggaaagc cggaaccaga gatctttttg aaagcttgtt caaaaatgaa tattcctcca
      481 agtgaagcac ttgtatttga agactcgatt gcagggatcg aagcagcaag gcgagcgggc
      541 attttgtctt ttctcatcaa agatcatttg atagggttgc ccgatcataa tgggaagcat
      601 aagttgaaag tagatgtaag tttatatgaa tccaataaag cagactatga attttatgac
      661 ctgcatcaag caaaacgatt tttagaaagt aaagggttgt atctctaata aagaggacta
      721 ttttctagtc ctctttattt attgtcctgc acgactgagg gaacagatga aaaagaagta
      781 attttttatt ttgaagtatc taccttattt gtagtgaaca atttagaaca aacacaaaac
      841 gcatctactg ttatctacca gtagatgcgt ttaaagagaa gaacgagaat cgtccatatg
      901 agggtttcca
//
LOCUS       DAFEEZ010000177          907 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000177
VERSION     DAFEEZ010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.187"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..881
                     /locus_tag="LP245_002972"
     CDS             <1..881
                     /locus_tag="LP245_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL1520802.1"
                     /translation="TSSVYRVMKRFYRPLNPFKQTLPKVLCFDEFKSVRSVASAMSFI
                     MMDGQSHALLDIVENRRLPYLERYFSRFSLATREAVQLIVIDMYAPYVSLVKKLFPNA
                     QLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHSQRGLGKKLKRYWKLLQKEEAKLN
                     YEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQLYQDILYAVKKRDQSLFEDCLTR
                     DISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGPLECLNNHIKVLKRNAYGFRNFYN
                     FKLRIMIRHGKTFLTK"
BASE COUNT          283 a          184 c          173 g          267 t
ORIGIN      
        1 ccacttcttc ggtctatcgt gtcatgaagc gattctaccg cccattgaat cctttcaaac
       61 agactttgcc aaaggtctta tgctttgatg aattcaaatc ggttcgaagt gttgccagtg
      121 caatgagttt tatcatgatg gacggacaaa gccatgcatt attggatatt gtcgaaaatc
      181 gacgcttgcc ttatttagaa cgctattttt ctcggttttc attagcgact cgtgaagccg
      241 ttcaattgat tgttattgat atgtatgcgc cttatgtttc gttggtgaaa aagcttttcc
      301 cgaatgctca gttgatcatc gatcgtttcc acatcgtcca acatattggc agaactttct
      361 tgaatcatcg agtgaaagaa accacggtac gacttaaagg aaattcccac tctcaacgag
      421 ggttagggaa aaaattgaag cgctattgga aactcctaca aaaagaagaa gcaaagttaa
      481 actatgaaaa acgggtttgg cgtgccagtt ttaaagatta tttgactgaa agtgagattg
      541 ccgatcgact gttagctgct tgtcccaact tacgccaagg ctatcagtta taccaagaca
      601 ttctttatgc ggtaaagaaa agagatcagt cactatttga ggattgttta actagagaca
      661 ttagcggtct gccagaaacc tatacaacca ctttacgaac gtttaaaaag tttctgccac
      721 agatccaaaa tgcgcttcac tacagctatt caaacggacc attggaatgc ttaaacaacc
      781 acatcaaagt attaaaacgc aatgcgtacg gctttcgcaa cttttacaat ttcaaactac
      841 gaattatgat tcgtcatggc aaaacatttt taaccaaata aacagaacag aaagaggttt
      901 tcttctt
//
LOCUS       DAFEEZ010000178          890 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.188, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000178
VERSION     DAFEEZ010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.188"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..888
                     /locus_tag="LP245_002973"
     CDS             <1..888
                     /locus_tag="LP245_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBL1520803.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          386 a          116 c          144 g          244 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt
//
LOCUS       DAFEEZ010000179          859 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000179
VERSION     DAFEEZ010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.189"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            28..>859
                     /locus_tag="LP245_002974"
     CDS             28..>859
                     /locus_tag="LP245_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1520804.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     V"
BASE COUNT          297 a          149 c          165 g          248 t
ORIGIN      
        1 ccaaagaatt ataaggagtg agtacaaatg acctataccc atcttacaac ggatgaactt
       61 gtaataatag agtcttattt caaaatgaat caatctgttg ctaaaactgc ccattgcttg
      121 aatcgttcaa gacaaacgat ccataaagta tatctgttct tcaagcaagg aaaatcagcc
      181 ttagaatatt atcaacagta taagaaaaac aaatcaaact gtggtagacg tccgcttgtt
      241 ttacccgagg aacaatcaga atatattcaa agaaaggttg ttcaaggatg gacacccgat
      301 gtgattgttg gtcgtgcagc gtttcctatt agttgttctg ctcgtaccat ttatcgtatg
      361 ttcaaaaagg ggctatttga ttcttctgac ttaccgatga aaggcaagcg taaaccgaat
      421 ggacatcaag aaagacgtgg aaaacaaact ttccgccgct ctattcatga acgtgaaaag
      481 gattatagcc aattctcaaa tgagtttggt caccttgaag gtgacactat cgtaggtctg
      541 aaacataaaa gtgctgtaat taccttagtt gaacgattat caaaagttat catcacattg
      601 aaaccgtgtg gtagacaagc gattgatatt gaaaaaaaat taaatcaatg gtttgaatct
      661 gtaccgaaaa acctattcaa atccatcact tttgattgtg gaaaggaatt ttcaaattgg
      721 aaacagatca gtaatgtcaa tgatattgcc atttatttcg ctgatccagg aacgccgtct
      781 caaagaggcc taaacgagaa ttctaacgga ttgttacgta gagatggttt attgaaatct
      841 atggatttca attcagtag
//
LOCUS       DAFEEZ010000180          820 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.190, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000180
VERSION     DAFEEZ010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.190"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            19..>820
                     /locus_tag="LP245_002975"
     CDS             19..>820
                     /locus_tag="LP245_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL1520805.1"
                     /translation="MPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILT
                     FLTGISSRDGEKFPVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTD
                     YDFAHLLFSDGSITQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVIS
                     TFALDFIHSNREIFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDD
                     LLDERLKNNIGLKFAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT          252 a          141 c          185 g          242 t
ORIGIN      
        1 ggagggtgga aagaaacctt gccagaaatt gcggatgaaa tcagtatcct caacttgacg
       61 agtaagtcag aaaatcaagg tctgcttgat ccttatgtga ttatgaagaa aaagaaagac
      121 tcggaaagtt tagcaattga tattctgact tttttaacag gaatttcaag tcgagacggg
      181 gagaagtttc ctgtgttacg taaagccatt cgaacggtga ctcaaagtga tcaacggggg
      241 ttattacaag ttattaacga attgcgaaaa gacgggtcac caatcgcgga aaatatcgcc
      301 gatcatatcg agtcctttac cgattatgat tttgctcatt tgcttttctc agacggctcg
      361 attacccaat cgattagttt agataaacag ctaaatatca ttcaagtggc ggatttggtt
      421 ttaccggatg cagaaacgac ttttgaagaa tataccacca tggaattgct tagtgtttcg
      481 atgctaatcg tcatttccac ttttgccttg gactttatcc atagtaaccg agaaatcttc
      541 aaaattgtcg atttggatga ggcttggagt tttcttcaag tggctcaagg aaaaacgtta
      601 tcgaataagc ttgttcgtgc tggtcgggcc atgaatgctg gggtctattt cgtcactcaa
      661 aatagcgacg atttattaga tgaacgttta aaaaataata tcgggttgaa gtttgctttt
      721 cgcagtaccg atattcatga aatcaagaaa accttggaat tctttggttt ggatcaggag
      781 gatcaaagca atcaaaaacg cctgcgagat ttggaaaacg
//
LOCUS       DAFEEZ010000181          791 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000181
VERSION     DAFEEZ010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.191"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..672
                     /locus_tag="LP245_002976"
     CDS             <1..672
                     /locus_tag="LP245_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1520806.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          292 a          123 c          147 g          229 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagtaa agaaatacgc tatcaagtat gctctattcc caagaagctc
      781 ccacttcaag c
//
LOCUS       DAFEEZ010000182          761 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.192, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000182
VERSION     DAFEEZ010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.192"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            51..731
                     /locus_tag="LP245_002977"
     CDS             51..731
                     /locus_tag="LP245_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HBL1520807.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEI
                     KVLLGIPA"
BASE COUNT          270 a          127 c          152 g          212 t
ORIGIN      
        1 tactatcaaa taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt
       61 ttaaaggaaa gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt
      121 ataaccttag ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc
      181 atacgacgat ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa
      241 agaaaaataa aaaatccttt tattcatgga aaatggatga aacgtacatc aaaattaaag
      301 gaaaatggca ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt
      361 tacgtaaaaa acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt
      421 ttgatgaacc gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga
      481 aactaaaaga atacggcttt tatcaaggga cagaacatcg taccattaaa tacctgaata
      541 atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac
      601 gcactgcctc taccacgatt aaaggcatgg aagccattcg aggattatat aagaaaaccc
      661 gaaaagaagg cactctcttc gggttttcgg tctgtactga aatcaaggta ttattgggaa
      721 tcccagctta aatcatagat accgtaaggg attttattct t
//
LOCUS       DAFEEZ010000183          705 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.193, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000183
VERSION     DAFEEZ010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.193"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(282..479)
                     /locus_tag="LP245_002978"
     CDS             complement(282..479)
                     /locus_tag="LP245_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL1520808.1"
                     /translation="MNNGTVKWFNSDKGFGFITGEDGNDVFAHFSAIQGEGFKSLDEG
                     QAVTYDIEEGQRGPQAVNIVK"
BASE COUNT          247 a          126 c           95 g          237 t
ORIGIN      
        1 cattgtgatc cacctctttt gtttattagt ttaaaccatc aaaccatttt taataaaata
       61 tgtaaattcc tttgctcaaa aaagtagctt ctttacgatt cgacaatttc aaataaagca
      121 ggtaaaaact ggctgtcaga aaatagccaa actgaagcaa aaaataatgt taaaattaat
      181 taatgaacga aaaaaatccc tcacctaata ttacggtgag gaattttttc taccgacata
      241 aacaaaaaaa ccacctcata tgaggcggtt aacgttcaac attattttac gatatttact
      301 gcttgaggac cacgttgtcc ttcttcaata tcataagtaa ctgcttggcc ttcatctaaa
      361 gacttaaagc cttctccttg gattgctgag aaatgagcga atacgtcatt tccatcttca
      421 ccagtgatga aaccaaaacc tttatctgag ttaaaccatt ttactgtacc gttattcata
      481 tatatttcct cctgatacgt atataatacg tgttttattg caattaatat tacttggtaa
      541 aaggagtttt tatagtgtga atatatcgct cagattacgt ttcaaattag attacttatt
      601 tactataaca cggatgtaat gctaacacaa ggataatcac tcgatatacg gtttaaatat
      661 tattatttgt caaattaagc gagacaaaac tttccattta cgtaa
//
LOCUS       DAFEEZ010000184          670 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.194, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000184
VERSION     DAFEEZ010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.194"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            232..399
                     /locus_tag="LP245_002979"
     CDS             232..399
                     /locus_tag="LP245_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520809.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPFILKGE"
     gene            404..628
                     /locus_tag="LP245_002980"
     CDS             404..628
                     /locus_tag="LP245_002980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520810.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQSKYFYDQL
                     ILQGFNRIRQKSPILYRWVMNAVRYEGYRW"
BASE COUNT          238 a          111 c          132 g          189 t
ORIGIN      
        1 aaacaggatc gacaaaataa acgaagggag gcaatctccc tcatcgtttt aaacttcttc
       61 ttagatagac agcaactaat tatgaagaaa aggatgtgaa ttcaactcct cctaaattct
      121 tcatcggttg ctgtttattt tgattagaca gcagcactca caaaactaaa catgttcttg
      181 tcgtctttca actgctgctg tctattaatt tatgtattgg agggaagaaa aatgaaatta
      241 tcagtagaag gcactccaga agaaatacaa gaattgctcc aagctattgg tagtagcaag
      301 gagcaaaagg taagtgtttc taattcagat attgacggta tttgcaattg tttaaacaga
      361 gaaaaaatat ctaatccttt tattttgaaa ggggagtaaa caaatgaacg aaaatcaatt
      421 aagagagttg tttaaaacga atgaagcaaa caaaacaatg gaggcgacat tctacgaaac
      481 tcaaaaaagc ttagcgttaa tcgcaaaaca atcaaagtat ttctacgatc agcttattct
      541 gcaaggattt aacagaatta ggcagaagtc gcccatcctc tataggtggg tgatgaatgc
      601 cgttcggtat gagggttacc gttggtaact cgaagaccga caactaaggc gtattgcctt
      661 tttattttgt
//
LOCUS       DAFEEZ010000185          630 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.195, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000185
VERSION     DAFEEZ010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.195"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..>630
                     /locus_tag="LP245_002981"
     rRNA            <1..>630
                     /locus_tag="LP245_002981"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          156 a          144 c          196 g          134 t
ORIGIN      
        1 gaaagccccc ggctcaaccg gggagggtca ttggaaactg ggagacttga gtgcagaaga
       61 ggagagtgga attccatgtg tagcggtgaa atgcgtagat atatggagga acaccagtgg
      121 cgaaggcggc tctctggtct gtaactgacg ctgaggctcg aaagcgtggg gagcaaacag
      181 gattagatac cctggtagtc cacgccgtaa acgatgagtg ctaagtgttg gagggtttcc
      241 gcccttcagt gctgcagcta acgcattaag cactccgcct ggggagtacg accgcaaggt
      301 tgaaactcaa aggaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga
      361 agcaacgcga agaaccttac caggtcttga catcctttga ccactctaga gatagagctt
      421 ccccttcggg ggcaaagtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg
      481 ttgggttaag tcccgcaacg agcgcaaccc ttattgttag ttgccatcat tcagttgggc
      541 actctagcaa gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat
      601 gccccttatg acctgggcta cacacgtgct
//
LOCUS       DAFEEZ010000186          609 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000186
VERSION     DAFEEZ010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.196"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            1..609
                     /locus_tag="LP245_002982"
                     /pseudo
     CDS             1..609
                     /locus_tag="LP245_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          249 a          107 c          111 g          142 t
ORIGIN      
        1 tctaagagaa cacgaagaac tttttcacaa gaattcaagc aacaaatcgt caatctttac
       61 ttagctggaa agccacgtgt agaaatcatt cgagaatatg aactaacggc ttcagcattt
      121 gacaaatggg taaagcaatc taaaacgagt ggttcattca aagaaaaaga taatcttacg
      181 cctgaacaaa aagaattgtt agaactacgt aaaagaaacc agcaattaga aatggaaaat
      241 gatattttaa agcaagcagc gctgatattc ggacgaagag acaagtaatc gatgcgaata
      301 agcatcttta ccctatatca gcgatgtgca gaatattagg tctatcacgt cagtcctatt
      361 attatcaatc aaaaccaaag aaagacgaat cagaacttga agaagtagtc gctgaagaat
      421 ttatccgcag ccgaaaggcc tacggctcaa gaaaaataaa aaaagcctta tcaaaacgag
      481 gcattcagat cagccgacga aaaattagta gaatcatgaa aaatagagga ttaaaatcga
      541 gctatactgt tgcttatttt aaagtacatc attctacttg caatgaagcc aaaacgacaa
      601 acgtattga
//
LOCUS       DAFEEZ010000187          592 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.197, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000187
VERSION     DAFEEZ010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.197"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..579
                     /locus_tag="LP245_002983"
     CDS             <1..579
                     /locus_tag="LP245_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL1520811.1"
                     /translation="GIKSHLWVTQNIWGDHTDPCGYLSEMGVSKEKLAYDLAHGFTDD
                     NPTTSDDNPTTSEDKPVIDPTRAGAANSTLTDGTNYAHVDQFGEIENANLHVAGWHIA
                     NYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVY
                     VMMRATNDPEGNTKGGAQDFHDKRWYLNIPQR"
BASE COUNT          203 a          105 c          122 g          162 t
ORIGIN      
        1 ggaatcaaat cgcatttatg ggtaacacaa aatatttggg gcgatcatac agatccttgc
       61 ggttatcttt ctgaaatggg tgtaagtaaa gaaaaactag cctatgattt ggctcatggt
      121 tttacggatg ataatccaac tacttcggat gataatccaa ctacttcgga ggataaacca
      181 gtaattgatc caactcgagc aggtgctgca aattctacgc tgacagatgg aacaaattac
      241 gcccacgttg atcagttcgg agaaatcgaa aacgcaaact tgcatgtagc tggatggcac
      301 attgctaatt ataaatacga gtatattttc attatggact acaatactgg aaaagaacta
      361 gctagagtaa gagctgatgg gatttataga ccagacgtaa atcaagctta taatacttta
      421 ggaaatgttg gctatcatgt atctttcaat atgcgtgatt tccctaataa gaaagtatac
      481 gtcatgatgc gtgcgacaaa cgatccagaa ggaaatacta agggtggagc acaagatttt
      541 catgacaagc gttggtattt aaatattcca caacgataaa aaattccccc ct
//
LOCUS       DAFEEZ010000188          548 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.198, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000188
VERSION     DAFEEZ010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.198"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..>548)
                     /locus_tag="LP245_002984"
     CDS             complement(<1..>548)
                     /locus_tag="LP245_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBL1520812.1"
                     /translation="SLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW
                     ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPT
                     IFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG
                     NDDLLEKYMSGKSLEALELEQE"
BASE COUNT          147 a          119 c           84 g          198 t
ORIGIN      
        1 tcctcttgtt cgagttccaa tgcttctaat gatttaccgg acatatattt ctctaaaagg
       61 tcatcgtttc cctctattac cgtatcccat tgttcagatt cggtaaagtt cgtcacacac
      121 atattaggat acagttctac cttctgtttg attacaattt cggcagaaag tttctcttta
      181 atatcctgat aaaccgttga taaatcaatt ccattttggt caatcttatt gataaaaaag
      241 attgtgggaa tccccatttt cctaagtgca tgaaataata tacgagtttg tgcttgtacg
      301 ccatcttttg cagaaatcag tagaattgcc ccatctaaaa ctgataatga acgatatact
      361 tctgctaaga aatccatatg tcctggcgtg tctatgatgt tcaccttcgt attttcccac
      421 tgaaaagagg ttattcctgt ctgaattgta attcctctct gacgttctaa aagcgtatta
      481 tccgtcctcg ttgtaccttt gtccacgctt cctaattctg taatcgctcc actgttatat
      541 aataagct
//
LOCUS       DAFEEZ010000189          542 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.199, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000189
VERSION     DAFEEZ010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.199"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..151
                     /locus_tag="LP245_002985"
     CDS             <1..151
                     /locus_tag="LP245_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL1520813.1"
                     /translation="SMDFREVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAF
                     YSSLI"
BASE COUNT          226 a           76 c           60 g          180 t
ORIGIN      
        1 atcaatggat tttagagaag tgaatcagac atttatttcc agtgtcagca atcaacgtaa
       61 tcatattcca agaaaatcat tgaattacag aacaccaatc gaaatatttt tgagctatgt
      121 acaagaagca ttttattcta gcttaatttg acaaatcata caaacaaaaa taaataaagt
      181 cggatttttc tgataattca acgcaaaaaa acgaacaatt tttcaataaa tcagtcttct
      241 aaaatagata acctaaaaaa aacgaacaaa caaataaaat gactgtcctt cattcactaa
      301 acatattttt attttttata ttgttaaaaa ttcacaatta ttttttaata gaattatctg
      361 ttttccaaat tttataacat aaaaaacctt ttttaacggc atttatatgc tttttcagaa
      421 attaactgat gatttcaaaa agaaaacatg tcataatatt tcccatattg tgcaaaaaaa
      481 tacaaggtgg aggctctact atgattgaag aatatattga gaaaaatatt ttaagacagc
      541 tg
//
LOCUS       DAFEEZ010000190          539 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.200, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000190
VERSION     DAFEEZ010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.200"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(264..527)
                     /locus_tag="LP245_002986"
     CDS             complement(264..527)
                     /locus_tag="LP245_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HBL1520814.1"
                     /translation="MKKNLLLVLPILGFAGFFVGVPMLSANIGISSYAAKKVIDIINT
                     GSTVATIISIVAAVVGGGLITAGIVATAKSLIKKYGAKYAAAW"
BASE COUNT          212 a           93 c           75 g          159 t
ORIGIN      
        1 tgaatttttt catgttgaaa acatcactaa tcaaaggcaa attataattt agaaatagaa
       61 tgaaaacact aaatgaaaat agaacattag aaaaaataga atcaaaaaaa cccaagacta
      121 gtgccgaaat aagggaaaca atcgaagcta caaaaaataa tgatttcgtt gaacaggacc
      181 aatttatttg tttccgatat ttctcaaaaa gaactttctt tgggaaagtt aaaggcgact
      241 gtaaagtcgc ctttagtcct tttttaccaa gctgctgcat atttagctcc atatttttta
      301 attaatgatt tggctgtagc aacaatacca gctgtaatta atccgcctcc aacaactgca
      361 gcaacaatag aaatgattgt agcaaccgtg ctaccagtat taattatgtc aataactttt
      421 ttagctgcat aagaagaaat tccaatgtta gcacttagca ttggtacacc aacaaagaat
      481 cccgcaaaac ctaaaattgg taaaactaat aataaattct ttttcataat aattcctct
//
LOCUS       DAFEEZ010000191          536 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.201, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000191
VERSION     DAFEEZ010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.201"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(6..359)
                     /gene="tnpB"
                     /locus_tag="LP245_002987"
     CDS             complement(6..359)
                     /gene="tnpB"
                     /locus_tag="LP245_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBL1520815.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(349..>536)
                     /locus_tag="LP245_002988"
     CDS             complement(349..>536)
                     /locus_tag="LP245_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520816.1"
                     /translation="LNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIYNGI
                     NNYILQAILKELLSNAL"
BASE COUNT          156 a          117 c           90 g          173 t
ORIGIN      
        1 ccagcttaaa aaactccttt ttttcctggc aaaatagctc gaggttgatc gatacttaat
       61 ccttctaaca accatcgaac ctgttggttc gttaaggttc gaacttcgtc tttcgtccga
      121 ggccatttta acttgccgtt ttctatccgc ttataacaga gaagaaaacc atcaccgtcc
      181 caatagagaa gtttgaaacg gtcttgacgg ttcccgcaaa ataaaaaaac ggcatcttcg
      241 taaagctcga gttgatactc ttgttgaata agactggcaa gaccatcaat tccttttcgc
      301 aaatctgttt ttccgcacac aatataaata tgtttggttt gaagtaaatc ataaagcatt
      361 ggacaacagt tctttcaaaa tagcttgaag aatataattg ttaataccgt tatagatcaa
      421 aacttcagaa ccattctctc ttttgatgcg catcgctaac ttggcagccg cgggtttacc
      481 tttttctggt gcactctttt cgtttcctaa ttggacagga acaatctcat ttaatt
//
LOCUS       DAFEEZ010000192          514 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.denovo.202, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000192
VERSION     DAFEEZ010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.denovo.202"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(<1..132)
                     /locus_tag="LP245_002989"
     CDS             complement(<1..132)
                     /locus_tag="LP245_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL1520817.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DAFEEZ010000193        23728 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.guided.041, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000193
VERSION     DAFEEZ010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.guided.041"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..212
                     /locus_tag="LP245_002990"
     CDS             <1..212
                     /locus_tag="LP245_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBL1520818.1"
                     /translation="ELEQEESIRFQNCSLFPLYHGSAKSNIGIDNLIEVITNKFYSST
                     HRGPSELCGNVFKIEYTKKRQRLAY"
     gene            447..683
                     /locus_tag="LP245_002991"
     CDS             447..683
                     /locus_tag="LP245_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520819.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            690..2642
                     /locus_tag="LP245_002992"
     CDS             690..2642
                     /locus_tag="LP245_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBL1520820.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2714..3211)
                     /gene="dfrG"
                     /locus_tag="LP245_002993"
     CDS             complement(2714..3211)
                     /gene="dfrG"
                     /locus_tag="LP245_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBL1520821.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3573..4613
                     /locus_tag="LP245_002994"
     CDS             3573..4613
                     /locus_tag="LP245_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBL1520822.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            4711..4899
                     /locus_tag="LP245_002995"
     CDS             4711..4899
                     /locus_tag="LP245_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBL1520823.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(4957..5310)
                     /locus_tag="LP245_002996"
     CDS             complement(4957..5310)
                     /locus_tag="LP245_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1520824.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            5841..6263
                     /locus_tag="LP245_002997"
     CDS             5841..6263
                     /locus_tag="LP245_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL1520825.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            6260..6490
                     /locus_tag="LP245_002998"
     CDS             6260..6490
                     /locus_tag="LP245_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL1520826.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            6988..7188
                     /locus_tag="LP245_002999"
     CDS             6988..7188
                     /locus_tag="LP245_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBL1520827.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            7215..8408
                     /locus_tag="LP245_003000"
     CDS             7215..8408
                     /locus_tag="LP245_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL1520828.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(8476..10041)
                     /gene="guaA"
                     /locus_tag="LP245_003001"
     CDS             complement(8476..10041)
                     /gene="guaA"
                     /locus_tag="LP245_003001"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBL1520829.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(10100..11023)
                     /locus_tag="LP245_003002"
     CDS             complement(10100..11023)
                     /locus_tag="LP245_003002"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBL1520830.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            11219..11824
                     /locus_tag="LP245_003003"
     CDS             11219..11824
                     /locus_tag="LP245_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL1520831.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12132..13148
                     /locus_tag="LP245_003004"
     CDS             12132..13148
                     /locus_tag="LP245_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL1520832.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13289..14590
                     /locus_tag="LP245_003005"
     CDS             13289..14590
                     /locus_tag="LP245_003005"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBL1520833.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14636..15298
                     /gene="deoC"
                     /locus_tag="LP245_003006"
     CDS             14636..15298
                     /gene="deoC"
                     /locus_tag="LP245_003006"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBL1520834.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            15319..15717
                     /locus_tag="LP245_003007"
     CDS             15319..15717
                     /locus_tag="LP245_003007"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBL1520835.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15783..16865
                     /locus_tag="LP245_003008"
     CDS             15783..16865
                     /locus_tag="LP245_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL1520836.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            17077..18639
                     /locus_tag="LP245_003009"
     CDS             17077..18639
                     /locus_tag="LP245_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL1520837.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18632..19765
                     /locus_tag="LP245_003010"
     CDS             18632..19765
                     /locus_tag="LP245_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1520838.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19765..20721
                     /locus_tag="LP245_003011"
     CDS             19765..20721
                     /locus_tag="LP245_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL1520839.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            20820..21986
                     /gene="deoB"
                     /locus_tag="LP245_003012"
     CDS             20820..21986
                     /gene="deoB"
                     /locus_tag="LP245_003012"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBL1520840.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            22010..22828
                     /locus_tag="LP245_003013"
     CDS             22010..22828
                     /locus_tag="LP245_003013"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL1520841.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            22845..23552
                     /gene="deoD"
                     /locus_tag="LP245_003014"
     CDS             22845..23552
                     /gene="deoD"
                     /locus_tag="LP245_003014"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL1520842.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT         7720 a         4202 c         4948 g         6858 t
ORIGIN      
        1 tggaactcga acaagaggaa agcataagat ttcagaattg ttctctgttc cctctttatc
       61 atggaagtgc aaaaagtaat atagggattg ataaccttat agaagttatt actaataaat
      121 tttattcatc aacacatcga ggtccgtctg aactttgcgg aaatgttttc aaaattgaat
      181 atacaaaaaa aagacaacgt cttgcatatt aagtagttca gttttggagt acaaaaagtg
      241 aaaatgtaaa cctaaatgag tatcaaattg caactgaatt tgatactcgt tttttattgt
      301 taaatcaacg tttgttgtta atttacacca caaaatgtaa gttaaaatgt atataaaaat
      361 gcgaacgtga aataattatt gtaggaatgc aaattggtgt gttaaaatgg ttacaattta
      421 ctaagcaaaa aggggtgcat tttcctatgc aatttcttga gccaaaaaat aagaacgcta
      481 agtctgtgga ttgggaaata tcagagcaag taagggtgat agttaagcaa tacgctgaat
      541 atgcagagcg tactgaaagc gaagcagtgg atgaattctt attgaacatt ttagacgata
      601 agaagtttat tgaatggatt gccaacaagc gaagtaataa gcggattgtt gaaaaaatgg
      661 gtatcaaaga tagagtgggt tgatagacaa tgaccaagct taaaagatta gccacgaagg
      721 aagatgaaat tgtagatgtt aaaattccga tttcaaacga agaattaaaa gatagggcta
      781 aacaatatga tttattaact ccaaaacgat ttgcaacaag gtataacaaa atgttgttct
      841 tgccaacgtc ttttaaatgg aacggttctg aatatcccat tcaatataat tactgcatca
      901 atccgttttg ttgtaatttt gggaaagaac agcacaaatt caaagatgta aaagggaaac
      961 caagtcgata taaaatgact ggtagttcca aagataaagg tcataaaggt atgtactgca
     1021 atgacaatcc tattggcaga ggtgtatcgc aaaactgtac agtaacccct ttatctaatt
     1081 ggtctgttgt tgaagaaatt aaacgcctta tagaaatcaa tagcatccaa gatgttgagc
     1141 cagattatca atttcataaa gaaggctgct cggaagaaga atcaacccca ttcaatgagc
     1201 cgaagcaatt ttacaaaagg gggaaaagta ggggcaaatc tcaacgctat caatgtaagg
     1261 cgtgtaagaa gttcactaat gttctaccaa aaagagaaga aaccactact tatcaccaac
     1321 aaaagaacac cattcttcca atgttcgcta agatggttgt tggaagggtt tcagtcagtc
     1381 gtacttgtga tattttagga attggagttg gaacctacta tcataagctg gagtggctgt
     1441 ataggcgttg tttggagttt ttagaacgat atgagacaca accccttcaa acaaagaaat
     1501 ttaacgagat gtggcttaat acggacaaga tgcactacta cctaaataac gtccgtaaga
     1561 aaggacaagg ttcaaagaaa tatacggggt ttgaagacct taatatgcaa acgtatatag
     1621 ttgtatctgc tgaggtctta tcaagatatg tgttccgttc tgatgttgcc tatgattgga
     1681 atatttcaat ggatgaatta aatgaagata caagaaaatt caaagaagac catctcaata
     1741 cttttagtcg taaaaatgat aggttagatt ggtcttatta tccacaagaa ccatccgcta
     1801 acgatagcga aaataggaat gcttatcttc acgaattagg gaaaattact aataggagta
     1861 gatttgtcga tggtttaaat gttgatgctc cttatactac aactgctcac tattggttaa
     1921 ttaaacaaat ggttaatgcc gacgaatggc gaatgattag tgatgatgac ttctctatta
     1981 gaaacgcctt ttatagagta ttcacgaaag aattaaggtt gagcgatgca catcatttta
     2041 tttgccaagt taacaagacg aaaagcagaa aacaatgctt aaaagaattc ggacaagcaa
     2101 aagcagaact gctcgattgg ggagatatca gaggattcaa aacaaagttt ctacggactt
     2161 tggcatctca ttatctaact gaattactaa caagtcatca attccacgaa gaggctatta
     2221 gtaaagatgg agaaagatat cgcaaatatg ccgataaccc tatcaaacat ccattagcca
     2281 ctaaggataa aggattttat tcagttgatt gtagaacgga tttatctgct ctggaaccaa
     2341 acgaaatcgc aaagatgcta ttaaatgtta atgaccattc gaccaatagc tttattcaac
     2401 agataagacg ttatatatca tctcttgaaa gaccattaac aacagctcgt ggtgataaga
     2461 agagctatat ttacgctaac ttcaatccga agtatgctca atttgcgatt acaattctaa
     2521 gaacttacta caacttttgt cgccctttta aatcagcgga taaaaaggtt ttgacacctg
     2581 ctcaaagatt agggattaca gataaacaat ttgattggaa agatataatt tatttcaaat
     2641 gacaaaaaga gcttggagta atcccaagct cttgtgcttt atctttactg ttcttcttca
     2701 attaacgcac ccgttaactc aataagtttt ttctttcata tacatgaaaa tagtagttat
     2761 acggattttt atcattcttt atcccttttt gggcaaatac ctcattccat tcctcataat
     2821 tcacttctgg aaaaaaagta tctccttcga attcatgatg tatttttgtg atgtacattt
     2881 tctcaacata agggaaaaac aaattataaa tctgttctcc tccgaaaata aaaatttctt
     2941 cttcgttttt acataactca aaaacatctt ctattgaatg aacaatttca caaccattaa
     3001 aggtaaaccc cttatctctc gtcagaataa tatttcttct gtcaggtaag gctcttccga
     3061 ttgattcaag gttcttccta cctaatatta tcggatgtcc ctttgtagta tttttaacat
     3121 attcccagtc cttgggaatc ctccaaggaa tgtcattctc tttgccaatc actctattct
     3181 tatccatcgc agcaatcaaa gaaactttca tttataacac agccttttta actaatttac
     3241 catctaattt cttatttcta tcaaaaaacc ttttctcatt atcctgcccg ttagttgaat
     3301 aagcaatttt ttctataagt tatattatca taataccaca aaatcacaaa ttttcattca
     3361 attatcattt tcaattgcat tttataaatc attttgtatg taatttggta tgtaagttaa
     3421 aatgaaaaaa gtagtccatt ttgaagtaca ttttgtcatt ttgtactcca aaactgaact
     3481 acttacttgc atatatacgc ctttatagtg gagtactaca tttacgagat tcggttagag
     3541 tatcagaaaa agaaaaaata aaagttacag aaatgtatac ttcaataaat ggtgaattat
     3601 gtaagattga tagagcttat tctggagaaa ttgttatttt gcaaaatgag tttttgaagt
     3661 taaatagtgt tcttggagat acaaaactat tgccacagag aaaaaagatt gaaaatccgc
     3721 accctctact acaaacaact gttgaaccga gtaaacctga acagagagaa atgttgcttg
     3781 atgccctttt ggaaatctca gatagtgatc cgcttctacg atattacgtg gattctacga
     3841 cacatgaaat tatactttct ttcttaggga aagtacaaat ggaagtgatt agtgcactgt
     3901 tgcaagaaaa gtatcatgtg gagatagaac taaaagagcc tacagtcatt tatatggaga
     3961 gaccgttaaa aaatgcagaa tataccattc acatcgaagt gccgccaaat cctttctggg
     4021 cttccattgg tttatctgta tcaccgcttc cgttgggaag tggaatgcag tatgagagct
     4081 cggtttctct tggatactta aatcaatcat ttcaaaatgc agttatggaa gggatacgct
     4141 atggttgcga acaaggatta tatggttgga atgtgacgga ttgtaaaatc tgttttaagt
     4201 acggtttata ctatagccct gttagtactc cagcagattt tcggatgctt actcctattg
     4261 tactggagca agcctttaga aaagctggaa cagaattgtt agagccatat cttagtttta
     4321 aagtttatgc accacaggaa tatctttcac gggcatataa cgatgctccc aaatattgtg
     4381 caaatatcgt aaatactcaa ctgaaaaata atgaggtcat tattattgga gaaattcctg
     4441 ctcgatgtat tcaagattat cgcaatgatt taactttttt tacaaatggg cttagtgttt
     4501 gtttagcaga gctaaaagga tatcaggtta ccactggcga acctgtttgc cagacccgtc
     4561 gtctaaatag tcggatagat aaagtaagat atatgttcaa taaaataact tagtgcgttt
     4621 tatgttgtta tataaatatg gtttcttatt aaataagatg aaatattctt taatatagat
     4681 ttgaattaaa gtggaaagga ggagattgtt attataaact acaagtggat attgtgtcct
     4741 atttgtggaa ataaaacaag actacgaata cgagtggata ctatacttaa aaatttccct
     4801 ttatactgcc ccaaatgtaa gaacgaaact ttaattaatg ttcaaaaaat gaatataata
     4861 acaatcaaag agccagacgc caagacgcag agccgataat ttgagaaatg aaactctcat
     4921 cttatcggct ctttttgttt atctgaattt tactgactag ccttcaatat ttcttgcttc
     4981 attgatacct tttgctagtg cttccattaa ggatagttct ttgtctgtaa agctatccat
     5041 gtatttttct acctgtaacc ttcgagtgct tttaatcaaa ttatctgtag gtaagaaaaa
     5101 ttcatcaata gatacatgga gtaatgatac aagatcatac agcacttgtg tacttgggtg
     5161 ttgtcctttg ttttctatat ttgttaaata acgtgggtca atttcaatca ttgttcccac
     5221 ttgttcacga gtgagacccc gtttcattcg agcctcttta atcgctaaac caacggctct
     5281 aaaatcgtat ttatcttctt ttttacgcat actaaatcac ctctatacat tttactgttc
     5341 ctatataacc ataaacaggt atagaaaaac atgttatata gtttatgagt tcctatagaa
     5401 cactgtggaa tttattaatg cgatgaatcc aatttcaaat agaaaggtcg ctgattttat
     5461 ttacctatac aactttataa aatttagtca tactcctaga aagtagataa aattggcgac
     5521 ttaatggagg gaaaagtcgc catgagaaag ataatctgtc atctagttct cttaattaag
     5581 ttcttatcaa aaaaacttat ccacctgtac tggatagata tgaccatcaa tgtggttttg
     5641 cagattacat agatagaaaa atcaaagcat atgaacagag aaaacaatct gtttatgtgc
     5701 ttttttggtc acttaataaa tatcttttag gatttctctt catttatgca acaaatcccc
     5761 cgttcgtgtc ggggtttagt atgaagggag ataaagaagc acatgccact ccctttcacg
     5821 acagaaaggg ggtgaaaagc atgaaaccat cttcttttca agaaaccata gaaaatcagt
     5881 ttgactatat ctgcaaacaa gttattgaag atgaacgaaa agattacttc aaacatctag
     5941 acagactatc agcaaaagaa gtctcgtttt ctgatataga taactacctt gtcaactctt
     6001 tttctactgt tgatacgtac gtcactgatt tccaactatt taaattattt ggattaagaa
     6061 tcaatgttga aagtgattta ttaagtgaag ccctgcgtca tctttcagag aaaaaacgga
     6121 acattatttt acttcattac tttatggata tgagtgatgt ggagattgcg gagttactaa
     6181 atttgaatcg ttcgactgtt tatcgtcatc gaataagtgg actagccatg attaaagaat
     6241 tcatgaagga gtgtaaagaa tgaaaacagc ttatccaagg gttcccttcc ccctcattgt
     6301 aaaggcgaca gatggcgacg tggaagcaat taatcagatt gttaaacatt atcgagggta
     6361 tacctcaaaa cgttcattac gtcgcatgac agacgaatat ggaaattctc atatggttat
     6421 tgatgaaacc ctacgtggca gaatggaaac gaaactcatc tctaagattt tatcgttcga
     6481 aattaaatag tcccattttt tcgtggaagc gtgtcgaatc gtatccacgc ttcccgattt
     6541 gggaggtttg ttattccatc aaagcatatt gtgtgttcag taggttttga taggctaaca
     6601 agccaaacgt tctttgacaa ccaaataaag gcaatcgaat acgtttcggt aagaaaagag
     6661 ctgatgaact aacacgccat gacctacaaa attagtgagc gattcatgtt agtaattcga
     6721 aagtaatctt tagcaggatt gctgccatga ctttcttatc gtgataatga tactcccgta
     6781 tagccatagt ccgagcgtta gaagcgtcac aggcaatggg tacggctaca tgagaaccat
     6841 gcagaagtga aattcctgtg agctttgcta gagctgttcg attgctaaga tattcttctc
     6901 ttgtcagtgt attattataa aactatttga tataattata ggtgaatatt ggagttttcc
     6961 tagcctataa ttgggaaagg agtaataatg ataacggtca caaaaaagga tttagttgag
     7021 ctaggatatg gaacttcttt ttcagcagac atcataaaaa aagcaaaaga attgatgatt
     7081 acaaaagggc atatctacta tcaatctcga aagctagata gagtccctcg tgaagctgtt
     7141 gaagaaattc taggaattcg gttttcaaat gaaaacaggt ctgagtagtt tttgcacagt
     7201 aaggagtaaa aactatggtt aaagacccaa taaaaaaagc aaagaatgga acctattatt
     7261 ttcgtgcaaa tctaggttat gattctaaag ggaaaaaaat tcaaaaatat cgtagtggat
     7321 tcactactaa aaaagaagca agagaagaat attcgaaact gctattgatg aaaccagaag
     7381 aattaagtga gaataaggat aaaatgacgt ttaaacatta tatctttgaa attttccttc
     7441 catggtataa gacacaggta aagctcagaa catatgaaaa tcgcttacca actattaaga
     7501 agcatttctc ttattttgat aaaatggctg tttccgatat tgagcctatt gatgtgcaaa
     7561 attggcaact aaaattatca aagaagtgta agtcttctta tgtaagagct gttcaaggac
     7621 tattttcagt tgctatggat cgagcaattg tccttgggat aaccaccaca aatccatcta
     7681 agattattgg caatgtgaaa aagcaaaagt ctaaaattga attttggaca aaagaagaat
     7741 ttgaaaaagt aatctctcta atttacaaag aagattacta tcaacacttt ttatttatct
     7801 ctctgtggtt tttatttatg actggaatgc gaattggtga agctactgcc attcaatggg
     7861 aagatattga ttttgactca ggagtactaa ccatcaacaa aacactctat tacaagaatc
     7921 aatcgaatta tagatttgtt gaaccaaaaa caaaggcgag cgttcgtcat attgtattag
     7981 ataaatgcac attaacttat ttatccgaat ggaaggaagt acaacaaaat ctaattcaga
     8041 cagactttgt aatgagctat aacggtattc ctacccaaaa acatacacta tcatatgcta
     8101 ttgaacgcta tgctaagctg gctggtatcc atcgaatcag aatccatggg ttacggcatt
     8161 ctcatgcttc cttgttaatc agtatgggag aaaatccact tatcattaaa gatcgtctag
     8221 gacacgaaga tattgagacg actttaggaa cgtatggaca tctttatcct aacagtaatt
     8281 tcgaggtagc taacaaatta aatggagcca tttcctttaa agaagcaaaa caaaattatg
     8341 atacttcacc aaagaatcaa tttactgtag actacttgcg aaacaaagaa atgaaaaaag
     8401 tgcaataaaa gtgcagtaaa aagataagaa gagccagaaa cccttggtat aagaggattt
     8461 ctagctctcc tacaactatt cccactccac tgttgctggt ggtttagaag tgatgtcata
     8521 cacgatacgg ttgacgtggg ctacttcgtt tacgatacgt acagagattt tttgcaagac
     8581 ttcccatggg atacgggcaa agtcagcggt cattccgtcg attgaagtta cagcacggat
     8641 accgactgtg tagtcgtaag tacgtccgtc acccataaca ccgacagagc ggatccctgg
     8701 aagaacagtg aaatattgcc agatatcacg gtcaagtcca gcagctgcga tttcttcacg
     8761 caagatagca tcagattcgc gtacgatttc tagcttgtct tcagtgattt cgccaagaac
     8821 acgaatacca agaccaggac cagggaatgg ctgacgccaa acgattgaat caggcatgcc
     8881 taactgagtc cctaattcac ggacttcgtc tttgaataat gtgtttaatg gttcgatcaa
     8941 ttcaaattgc atatcttctg gcagtccacc tacattatgg tgagatttga tcgtctgtgc
     9001 tgtttctgta ccagattcga taacgtcagt atacaacgtt ccttgtgcta ggaaagagac
     9061 gccttcttca ccagcaagtt ttgttgcttc gtcatcaaaa acatatacga attcattccc
     9121 aatgatttta cgtttttgtt ctgggtcaga tacacctttc aacttgtcta agaagcgatc
     9181 tcttgcatcg actttgatga tgttcaagcc gaattttccg cctagacttt ccattacttg
     9241 ttccgcttcg cctttgcgta gcagaccgtg gtcaacaaag atagatgtca attggtcacc
     9301 gatcgctttt tgtaaaagaa ccccaacgac actagaatca acgccacctg aaagaccaag
     9361 caagactttt ttgtcaccaa cttgttcacg gattttttct acttgcatat cgataaagtt
     9421 atccattgtc cagttacctt cacagtgaca aacatcaaag gcaaagtggc gcagcaattc
     9481 gattccgtat tcggaatgac gtacttctgc atggaattgg ataccataaa aattacgtgt
     9541 tgtgtcttgg atagaagcaa tcggacaatc tttgcttgtt ccgactgttt caaagccttc
     9601 aggaacttta gttaccaagt caccatggct catccatact gtttgttgtt ttggtgtttc
     9661 tttaaacaag acagcttgat cgcttgttac ttctaacaag gctttcccat attcgcggtt
     9721 tttagcaggc tctacggaac cgccaagttt gtacgtgatc aattgcatac catagcaaat
     9781 ccctaataca ggaataccta aattgaagat ctcaggatcg atcccaaatg cattctcatc
     9841 atatacactg tttggtccgc cagaaagaat gattcccttt ggattcatcg cttttacttc
     9901 ttctgcagta atgcggtggc tcaataattc ggaaaagact ccaagatcac gaatacgtct
     9961 tgtgatcaat tggttatact gactaccgta gtctaatacg ataatctttt caacgttcgt
    10021 catatcggca acgtttgtca aatttattac ccctatccct ttaaatttta tctcaaaata
    10081 gtcaaactat tttaaaatgc taatattttc gcatgaaaat cgaatcgatg atatgatttt
    10141 cagttttatg gagaattata tcggctcttc ctcgtgtagg caagatatat tcctgtaaat
    10201 ttttcaaatt cacatttttc catacatctt ttgccatttt aaaggcttct tcacgatctc
    10261 cgatagcaaa acgataataa taattctctg gattttggaa agccgtatcc agtaacgcac
    10321 caaaacgatc caaataccat ttttcgatca gcacgggatc ggcatcgaca tagacagaaa
    10381 aatcaaaaaa gtcgctgacg tagatttgct gattcgcagg taattgaagc gtattgatcc
    10441 cctcaacgat caagatatca ggctgctgga tcaattcgta cttgtctgga atgatatcat
    10501 acacatcatg tgagtaaaca ggtactttta tctcttcctg accagatttt acacggttca
    10561 agaaatcgat cagcatctcc atatcataac tttcaggaaa tcctttacgg tccatgattc
    10621 cacgctcttt taatatacga tttggataaa gaaatccgtc agtcgtgatc agctgaacgt
    10681 ttcttcgttt gaaggtacga gacaaaatcg tctgcagcag tctggctgtt gtactttttc
    10741 caacggctac acttccggcg atcccgataa taaaaggcgg tacttctacg tatttatgaa
    10801 gaaataaacc tttactcaag aacaaagatt caaattcttt catataaaga taaatcagat
    10861 gagcaagagg tacatagata tctcgaacat cctgcatgga aatgcggtca ttcaaacttt
    10921 tgatattatc tagttcatct tgtgtcaaag gtgcttgccc attacgataa aattctcgcc
    10981 attcttctct tgccacacgg tagtagttca ttggatcatt catattagcc tcctgcgttc
    11041 tcccatcaat ggaactattt taacacaaaa taaacgcaaa ccccaccact taagagagat
    11101 tgccgatctt tttgtataat ctttataata gaaagaaacg gagtcttatt cttgacttgc
    11161 gcacggatac ataaaaggat agactgttgt catgaaagaa atgagaagga tggaagacat
    11221 gacaaatcat tactattctg aacgcccaga tacggcgcac gattttgaac aatgggcttt
    11281 tgagttaaaa ggcagaacct ttcaatttgt aacagattct ggtgtatttt cacgtgaaac
    11341 agtggattat ggttcacgtg tcctgattga tgctttcgat tgggaagagt tacctgatga
    11401 aggaaagatc ttagatgtgg gatgcgggta tggaccgatt gggttagctt tggcatttgc
    11461 gacacagcgg tttgttgaaa tggtcgacat taatgaacga gcggtaagtc tagcgcaagg
    11521 aaacgcaaag cgtaaccaaa tcgaacatgt tgatatccat caatcgaata tctatgaagc
    11581 agttcatgaa gaaacctatg cagctatcgt aagcaatccg ccgatccgtg ctggaaaaaa
    11641 agttgtacat gaaattttga caggcgcata tcctcggttg aagaagggcg gtacactgac
    11701 aattgtgatc cagaagaaac aaggagcgcc gagtgcgcaa aagaaaatgg aagaaacatt
    11761 tggtaatgca gaaatcgtca caaaagataa aggatattat atcatcaaaa gtgtgaaaga
    11821 ataactagct gaaaaatagt ggagcgacga aagagtggaa ctgggcgtgc atgtacgggt
    11881 acgtatcagt tctttttttg ttgagaagtt tttaaaaaca aagaactatt ttttcttcaa
    11941 aaagaaatag taggaacaga gtcgttgttt tttacgataa aataaataag atacagaact
    12001 tgtatagaag gctgccaagt cggtagataa aggaggtttt tatcaaaaaa catactttcc
    12061 ttttttctct attcttttct tgggggtttt ggtacactga tagggaattt agatagaagg
    12121 gagccaatag gatgaagctg accatcagag atatcgcaga aatggcaggc gtatcagtaa
    12181 caactgtctc acagattttg aataacaaag gaagcagatt tagtgataag acaagaaaaa
    12241 aagtgttgtc gatcgtgaat gaacatcatt ataagcccga ttatttcgct tcaaatgtga
    12301 tcaatcgaca ttcaaagacc atcggaatga tcgtccctga tgtcactgat ttcttcttct
    12361 ccaaactgat cgaaggtgta gagagctatt tgaatccttt gggctatgtg atcatgttat
    12421 gcaattctcg tcatagccaa gaaaatgaga tcaagtattt acaagagctt tcccaccgct
    12481 cagtggacgg aatcttgctg gccacaccaa atattttacc tgagaaatat gcattagaca
    12541 gcggttttta tcaaaaaatg ccaatcattt taatcgatcg cggattgaat cgtcgggata
    12601 acggacggct tatcgtaaag gaatatgagg gcgcctatca agctgtttcg ctgtttattg
    12661 aaaatggcca tacgaagatc ggcatgctga aggaaaccac tggatactat caattagaag
    12721 aacgtttcaa cggatatcgt catgcgctga aagatcatgg cctgcctttt aatgggaaat
    12781 ttgttgaaca tggagagttg actgtccaag gtggatatac tgcatcaaaa aaattactca
    12841 aacataaaga tatcacggct attttttgcg ggaatgatgc catggcgatc ggatgctatc
    12901 aggcgatcga tgaattgggc aaaaaaatcc cagaagatat ctcagtcata ggattcgatg
    12961 gattaaagct gtcagaatac atgattccgc aattgacgac agtgcagcag ccaagttttg
    13021 atattggatt ttatgctgca cgtttcctga tcgatacgat cgaatttcct caaagaaaag
    13081 ttccgaacaa agtgttcgaa acaaaattaa ttattcgtga gagcgtaaaa gtattgacaa
    13141 agggctaact cggcggtata ttgcttatgt aagcatttac aaaggctagt tagtgctttt
    13201 tttattttta gtaaaccagt ttactaaagt ggtttacctt tcctaaaaat aatgtataat
    13261 accgaatgaa gacaaggagg atcaggcaat gcgaatggtg gatctgattg aaaaaaagag
    13321 ggatggaaac gagctgtcga aagaggaaat cgagtacatc gtcacgaact atacgaatgg
    13381 aaagattcca gattatcaag tcagtgcatt attgatggca attttttatc aagacatgac
    13441 aaatgaagaa atcacgaact taacattggc gattgctaat tctggtgatg tcatcgattt
    13501 gagttctctt gaaggaataa aggtagataa gcattcgaca ggtggcgttg gtgacacgac
    13561 cacattgatt ttagcccccc tagtagctag tgtcggagtg acagtggcta aaatgtctgg
    13621 acgcggtcta ggttacacag gtggtacact agacaagcta gaagcaattc ccggatttca
    13681 gatcgagctt tcggatgaag aatttgtacg cattgttaat gaaagtaaag tagcggtaat
    13741 tggtcaatca ggaaacttgg caccggcgga caaaaaattg tatgccttgc gtgacgtcac
    13801 agcgaccgtt gattctcttc cgctgattgc cagttcgatt atgagtaaaa aaatcgcggc
    13861 aggagcagat gcaatcgttt tggatgtgac cactggagac ggtgctttca tgaagaacat
    13921 cgaagatgca agacgtctgg caaagaccat gacgagcatt gggaaactgg ctaaccgaga
    13981 aacagtggcg gttatctcag atatgtcaga acctcttggc gaagctatcg gaaatagtct
    14041 agaagttgtc gaggcaatcg aaacattaca aggaaatggt ccagaagatc tagtagaaat
    14101 gtgctacgcc ttaggaagcc aaatggttgt tcttgctggc aaagctaaga caaccgatga
    14161 agcaagaacg ttgcttcaag aagctctgga atcaggtaaa gcgttagcaa aattcaaaga
    14221 aatgatccaa aatcaagggg gagacccagc gatcgtggaa catccagaac gaattttgac
    14281 tgcacgctac acaatggagc ttcctgctaa acaaagcgga gttgtgtcaa aaatcgtggc
    14341 aaatgaatta ggaattgctg caatgatgct aggtgctggg cgtaaaacca aagaagaaga
    14401 tattgatcac gctgttggat tgaaactgca taaaaaaatt ggtgacactg tgacaaaagg
    14461 tgagtcacta ttgacgatct atagtaacga cgaagaaatc acttctgtca ttgaattatt
    14521 atataaaaat attgaaattg gtgaatcggc aatgaagcca acgttgattc atgacatcat
    14581 cacagaataa aggaaaaaag cggactttac cgttttaaag aaaaggggaa aagaaatgga
    14641 actaaaccga atgatcgacc atactatttt gaaagcagac gcatctaaag aagctgtgat
    14701 gcaaattatc gaagaagcaa aaaaatacca tttttattct gtctgcatca atccagcatg
    14761 ggttgcgcta gcgaaagaac aattacaagg tgagccagta gccgtatgta cagtaatcgg
    14821 gtttcctcta ggagcaaaca cacccgagac aaaagcattt gaaacaacag atgccatcaa
    14881 taacggtgca gatgaagtcg atatggtcat caatatcggt gctttgaaat caaaggatga
    14941 tcaacaagtc caaaaagata tcgaagcagt tgttgaagca gcaaaagatc gtgcgcttgt
    15001 caaagttatt attgaaacat cgttattaga tagagaagaa atcatccgag cttgcgaaat
    15061 agcaaaagct gcaggcgctg attttgtcaa aacatcaact ggtttctcaa caggcggagc
    15121 aaaggtagag gatgtccgtt tgatgcgtga aactgtagga ccagaaatgg gtgtcaaagc
    15181 ttccggcggt atccataacg aagaagaagc aatggcaatg atcgaagctg gtgctacaag
    15241 aatcggaaca agcgcaggag tagcaatcgt atctggttca actggtgaag gctattaatt
    15301 ttttcaaagg agaagctcat ggcagaactc aaacaagaat ggatcaacac agctattgaa
    15361 gcgttagata aagcctatgt tccttattcc cattttccgg taggcgcttg tctcgtaacg
    15421 gaatcaggca agatttatca aggcatcaac attgagaatg catcatttgg attaacgaat
    15481 tgtgccgagc gcacagcttt tttcaaagca gtatctgaag gagaaaaaac atttacgcat
    15541 ctagtcgtag cggggcacac ccccgatcct atctctcctt gtggtgcatg tcgacaagta
    15601 atggcagaat tctgttcccc tgatatgccg gttacgctag taggagacaa tggtgtgacg
    15661 aaggcaacga ccgttcgtgc actgctgcct tatgcattta ctgaaaaaga tctataactc
    15721 atgttcattc agtcagctga ctgttgaaaa ataaaacaat tattttagga ggctttacag
    15781 aaatgaaaaa agcaaaatta tttggtttag gtgctgtcgc actagcagca gggttatttt
    15841 taggtgcatg cggcaacaac ggctctactg attcatccgg tggcaaaagc tcatcagaca
    15901 caacaactgc agcattgatc acagacacag gtggtgtaga cgaccgttca ttcaaccagt
    15961 cagcttggga aggactagaa aaatggggga aagatcaagg actttcacga ggaaatgatg
    16021 gcttccaata tttccaatct tcaaatgaat cagattacat cccaaatatt gaccaagcat
    16081 tgaatgctgg attcaaaacg atttttggta ttggttataa actaaaacca gcgatccaag
    16141 aacaagcaac aaacaataca ggtacgaact ttgttattat cgatgatgtc atcgatggat
    16201 tagataacgt tgtatctgca actttcaaag acaacgaagc ttcttatctt gcaggtgttg
    16261 cagcagctta tacgactgaa acaaacgtag tcggctttat cggcggtgta aaaggtgaag
    16321 taatcgatcg ttttgatgct ggattcaaag ccggtgttga tgcaggtgcg aaagaattag
    16381 gaaaagaaat caaagtattg aatcaatatg ctggtgactt ctctgctcca gataaaggac
    16441 gttcaattgc tcaaggtatg tatgcacaaa acgcagatat catcttccat gcttcaggcg
    16501 gtacaggtaa cggtgtattc caagaagcaa aatcattgaa cgaatcaggc gacaaaaaag
    16561 tttgggttat cggtgttgac cgcgaccaat cagacgaagg cgaatacaca ttaaacggcg
    16621 aaaagaaaaa cttcacattg acatctacac tgaaagcagt tggaacagta gtagaagatt
    16681 tggcacaaaa atcagcggac ggtaaattcc ctggcggcga acacactgtt tatggattga
    16741 aagaagacgg tgttggtcta acagaaggac aactttctga cgaagcgaaa aaagcagttg
    16801 atgaagcaaa agaaaaaatc atttcaggtg acgtaaaagt tccagaaact cctgaagaaa
    16861 actaaaacca tttctatagc cttgttagac acatgtttga caaggctatg gtttgattag
    16921 aacaagaatt tttcatttat ccaagctgcc ttgtgacagt ttggataagg gaacaactcc
    16981 ctgaagtaat gtttgtttca aaagaagaac gctcactaag cgtgaatctt agtcaatcgt
    17041 tgccctagat agaaatcgtt aggatgtgaa aaaaaggtgg ttcaagaaaa tattgtcata
    17101 gaaatgcaga atattaccaa agaatttgga acattcaagg caaatgacaa catcaattta
    17161 caagtaaagg caggagaaat tcatgcgttg cttggagaaa acggtgctgg caaatctaca
    17221 ttgatgaacg tgctttccgg attattagag ccgacatcag ggaaaatttt gatgcgtggg
    17281 aaagaagtaa agatcacaag tccgaccaaa gccaaccaat tagggattgg gatggtccat
    17341 cagcacttta tgcttgttga tgcctttact gtaacagaaa acatcgtgtt gggaagcgag
    17401 cctagtcgcg cagggatgct tgaccataaa aaagcacgaa aagagatcca aaaagtttct
    17461 gaacagtatg gattgtcagt caacccagat gcttacgttc gtgatatttc agttggaatg
    17521 gaacaacggg tagaaatttt aaaaacactt taccgaggag cagatgtact gatttttgat
    17581 gagccgacag ctgtattgac ccctcaagaa attgatgaat taatcgtgat catgaaggaa
    17641 ttagtcaaag aaggcaagtc gatcattttg attacgcata agttagatga aatcaaagca
    17701 gtagctgacc gctgtacagt tatccgccgt ggaaaaggaa tcggtacagt caacgttaaa
    17761 gacgtaacct cacaacaatt agccgatatg atggttggaa gaacggtttc attcaaaacg
    17821 atgaaaaaag aagcgaagcc tcaagaagtc gttttgtcta ttgaaaatct agtggtgaaa
    17881 gaaaatcgtg gattagaagc cgtgaaaaac ttgaacttag aggttcgtgc tggcgaagta
    17941 cttggtatcg ctggaatcga tggaaacggg cagtcggagt tgatccaagc tttgactggt
    18001 ttgcgaaagg cagaaagcgg acatatcaag ctaaaagggg aagacatcac taataaaaaa
    18061 ccccgaaaaa tcactgaaca tggtgtagga cacgtgccag aagaccgtca taaatacggg
    18121 ttagtcctag atatgacatt atctgaaaat atcgcactac aaacctatca tcaaaaacct
    18181 tacagtaaaa acggcatgct gaattattca gtaatgaatg aacatgccag agaattgatc
    18241 gaagaatatg atgttcgaac aacgaatgaa cttgttcccg caaaagcttt atcaggcgga
    18301 aatcagcaaa aagcaattat cgctcgtgaa gtcgaccgag atcctgatct gttgattgtt
    18361 gcaaatccaa ctcgtggact ggatgtaggt gcgatcgaat ttattcataa acgtctgatc
    18421 gaacaaaggg acaaatacaa agcagtgtta ctgatcagtt tcgaattaga agaaatttta
    18481 aatgtttcgg atcgtattgc tgttatccat gaaggagaaa ttgtcggtat cgttgatccg
    18541 aaagaaacat ctgaaaatga attaggtcta ttgatggcgg gctatacctt agaagaagca
    18601 cgaaaagagt tagaaaaggg ggctggcgca catgaatgat cgcagcgaaa aattccgtaa
    18661 tttattagtg cctgtacttt cagttgtttt aggattgatc ttaggcgcga tattgatggc
    18721 tgcttttggt tttcagccca tccaaggtta ttcttctatg ctagatgcag cccttggttc
    18781 gcaaagaggg ataggtgaaa cgttaaggca agcaacgccg ttgattttta cagcattagg
    18841 tttttctgta gctaactcag ctgggttttt caatattggg ctttctggac aagcactttg
    18901 cgggtggatc gtcagtgtct gggtggcact tgcgtttcca gatctgccaa aagttgtttt
    18961 gcttccgtta tgcgtgatct taggtgcctt agctggtgcg atggcagcgg ctgttccagg
    19021 tttacttcga gcattttttg gaacaagtga agtgatcgta acaatcatga tgaactatat
    19081 cttattatac gtaagcacat ttgctttaca tgaagtgatg cctgaaagct atcgctcaag
    19141 tttggactct tccaatatga tcagtcaaaa tgcctcactg cggttaccat ggttaacaca
    19201 agcttttggc ggctctcgcg taaactcagg attattttta gcaatcatcg cgcttatttt
    19261 cgtttggctg ctgatgaaga aaacgacttt aggatttgaa atccgttctg ttggattgaa
    19321 tccttttgct tctgagtatg caggaatgag tagtaaacgt acgatcgttt tgtcgatggt
    19381 catttctggc gctttggcag ggcttggcgg tgtggttgaa ggattaggaa cgtatcaaaa
    19441 cttctttgtt caaacgactt cgctatctat tggatttgac ggaatggctg tttccttgct
    19501 tggttctgga tcagcaatcg gtattctttt atcagcgatc ttgttcagta ttttgaagat
    19561 cggtggactt ggcatgcaga caggagcagg tgttccgttt gagatcgtca atgtatcgat
    19621 tgctttgatt atcttctttg tcgggatcaa cttcctgatt cgtttcgtca tggctaaagt
    19681 cttccaaggg aaaaaacaag aagagatcgt tgcgacaata gaatcgaaac caacgaatca
    19741 aaaccatgaa gggggcgaac tataatgtcg actatcgaat taattgcctt gatccttact
    19801 tctacactgg tttattcaac accgctaatt ctaacgtcac taggcggaac tttttctgaa
    19861 cgaagcggga tcgtaaacgt agggctagag ggaatcatgg tcatgggtgc ttttagttcc
    19921 atcgttttca acttgacgat gagtccatca cttggttcta tgacaccatg gatcgctatt
    19981 ttagtgggtg gcgtcgtagg tatcctattt tctctgattc acgcagtagc aacagtcagt
    20041 ttgcgtgctg accatattat cagcgggaca gtaattaatc tgatggcacc tgctttaggt
    20101 gttttcttga tcaaagcatg gtatggtaaa ggtcaaactg ataacatcac gcagaatctg
    20161 gggtattttt ctttcccagg attagcagat attccggtca ttggaccaat tttctttaaa
    20221 aatacattct tacctgctta ttgtgctatt ttgattgctg tcctagcttg ggtgatcatc
    20281 ttcaagacga aattcggctt gcgcctccgt tcagttggtg aaaatcctca agctgccgac
    20341 acattaggta tcaatgtata tgctatgcgt tattcaggcg tactgatttc tggcttgtta
    20401 ggcggtatgg gcggtgctgt ttttgctcag tcgatttccg gtaacttttc agctggtacg
    20461 atcgttggac aagggttcat ctccatggct gctatgatct ttggtaagtg gaatccttta
    20521 ggggcaatgg gtgcctcatt gttctttggt tttgctcaaa gcttgagtat cattggcgca
    20581 caattaccag ttatttcttc gattccgcca gtattgctgc aaattgctcc atatttgctg
    20641 acaatcattg tgctggttgt tttcttaggg aaagcttctg gtccaaaagc aaacgggaag
    20701 aactatatca aatcaaaata atcttttagc gaataaaaag ggtgggttac gggaagtgtt
    20761 tttcgtctcg ccctttttgt tttaaaggca ataaaaataa aaagaaagaa ggaataatca
    20821 tgtttaaacg cgtacatctg atcgtcatgg attcagtagg aattggagaa gcaccagatg
    20881 ccgataagtt cggtgatgtt ggttctgata cattaggaca cattgcgaaa gaagcaggat
    20941 tgaacgttcc acatttagag cagcttggtt taggaacgat ccgtcctctt gaaggtgtgg
    21001 aatcagtgaa agatcatcaa ggctatgcga cgaaattaga agaagtttct gtagggaaag
    21061 atacgatgac aggccactgg gaaatcatgg gattgaatat caaaactcca tttcgtgtgt
    21121 ttcctaatgg attccctgat gatctgatca aacaaatcga agaattttct ggccgtaaag
    21181 tcgtatgtaa caaaccttat agcggaacag ctgttattga cgattacggt gaacaccaaa
    21241 tgaaaacagg cgatttaatt gtatatactt ctgccgatcc tgtccttcag atcgcggcac
    21301 atgaagaaat cattccttta gaagaattat atcggatttg ccaattcgtt cgtgatataa
    21361 caaaagatga tccgtatatg attggccgaa tcattgcacg tccgtacgtg ggtgaaccag
    21421 gagacttcac acgaacaagc aatcgccatg attatgcgtt gaatccattc ggacacacag
    21481 tccttgattc tttgaaagaa gcaggaaagg acgtgattgc tgttggaaag atcaacgata
    21541 ttttcaacgg acaaggaatc actgaatctg tccgcacgaa aagcaatatg gatggcgttg
    21601 accagctgct gaaagttatg aaaaacgatt tttcaggaat cagctttacc aatttagtag
    21661 attttgatgc attatacggt catcgtcggg atgtagtcgg ctatgcgcat gcgattgaag
    21721 aatttgactt acgaattcca gaattgcttg aagcgatgga agaagacgac ttgctaatga
    21781 ttacagccga tcacggaaac gatccgacgt ttactggtac cgatcatacg cgagaatatg
    21841 taccgttatt ggtttacagt aaaaaaatga aagaacaagg ggcattgcct caaggatatt
    21901 attcagatat ttcagcaacg attgctgaga actttagtgt ttcttcgact gaaaatggcg
    21961 aaagcttctt gaaattatta aaataatctt tttaaatagg agaaagcaaa tgaccaagtt
    22021 aagcgagatg ttacaagaaa cgacccagtt tatccttgat aaaggagtaa aagaaattga
    22081 ttttggtttg attctaggtt caggattagg tgaattagca gatgaaatcg aagatgctgt
    22141 aatgatttct tatgatgaga tcccgttctt tcctgtttcg acagtagttg ggcatgcagg
    22201 aaagctagtt tatgggtctc tggcaggcaa gaaagtgtta gccatgcaag ggagattcca
    22261 ctactatgaa ggtcattcca tgcaaacagt gacctatcca gtacgtgtga tggccggact
    22321 aggggcccat tcagtcattg tgactaatgc atgtggtggt gtcaacgaat catttgtacc
    22381 aggagatttg atgctgatta ccgatcatat caattttact ggtgaaaatc ctttgatcgg
    22441 tccgaatgaa gatgcaatgg gccctagatt tccagatatg agtcaagctt atacgcctga
    22501 ctatcaagca acagcaaaag cagcagcaga aaaactaggt ttggatctta aagaaggcgt
    22561 atatatgggc tattctggac caacttatga aacgcctgcg gagatccgaa tgtctcggac
    22621 aataggagcc gatgcagtag ggatgtcgac tgttccagaa gtcatcgtag cagctcacag
    22681 cggattaaaa gtgttaggaa tctcttgtat taccaactta gcagcaggta tgcaagcgaa
    22741 tctgagccat gaagaagttg tagaaacaac tcagagagtc aaacaatctt ttaaagcatt
    22801 ggttaaagaa acattgacat tattgtaata ggaggaacaa taaaatgagt gtgcatattg
    22861 aagcgaaaga aggcgagatc gccgataaga ttttacttcc gggagatcct ttgcgagcta
    22921 aatatattgc ggagactttt ttggaagatc cagtttgtta caatcaggta cgcggtatgt
    22981 taggctttac cggcaaatat aaaggagaac gtatttctgt tcaaggaaca ggaatgggaa
    23041 tgccatcagc caccatctat gcccatgaat tgatccagtc gtatggtgta aagaaattga
    23101 ttcgagtagg tacatgcggt gcattgtcaa aagacgtcca tgttcgtgat ttagtactag
    23161 cacaaggtgc agcgaccagt tcttcgatga tcgaaaaaaa tttccaagcc tttcattttc
    23221 ctccaatcag tgatttcaat ctattactga aagcatatga gatagctaaa gaaaagggct
    23281 atacggttca tgtaggaaat gttctttcgg aagattcttt ctacaaagat gatttgacag
    23341 agacgttcca attagctgaa cttggcgttt taggagtgga aatggaagca gcggctcttt
    23401 attacttagg cgcgaaatac catgtgcaga cattaagttt gatgaccgtt agcgaccatt
    23461 tgatcaccgg tgaagaaaca acagctgcag aacgtcaatc tacgttcaat gaaatgatcg
    23521 aagtaggatt ggaaacagcg atagcagaat aagaaggaaa tgaaaaagct gccctgcatt
    23581 aagtaataag aacatccaag caaaaatagc tcctcatgtt tttgacttgg ctggacttat
    23641 tattgcaaat gtaagctttt gaacaccgtt taccaagagg ttgtgaatct gccgtttaac
    23701 tctgagtcac aaggaacaat ttcaaaaa
//
LOCUS       DAFEEZ010000194        20862 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.guided.048, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000194
VERSION     DAFEEZ010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.guided.048"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            267..1304
                     /locus_tag="LP245_003015"
     CDS             267..1304
                     /locus_tag="LP245_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL1520843.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(1393..1716)
                     /locus_tag="LP245_003016"
     CDS             complement(1393..1716)
                     /locus_tag="LP245_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBL1520844.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(1703..2410)
                     /locus_tag="LP245_003017"
     CDS             complement(1703..2410)
                     /locus_tag="LP245_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBL1520845.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            2496..2837
                     /locus_tag="LP245_003018"
     CDS             2496..2837
                     /locus_tag="LP245_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HBL1520846.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(3008..3856)
                     /locus_tag="LP245_003019"
     CDS             complement(3008..3856)
                     /locus_tag="LP245_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520847.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            4454..5317
                     /locus_tag="LP245_003020"
     CDS             4454..5317
                     /locus_tag="LP245_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL1520848.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            5417..5899
                     /locus_tag="LP245_003021"
     CDS             5417..5899
                     /locus_tag="LP245_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL1520849.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(6162..6629)
                     /locus_tag="LP245_003022"
     CDS             complement(6162..6629)
                     /locus_tag="LP245_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBL1520850.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            6752..7603
                     /locus_tag="LP245_003023"
     CDS             6752..7603
                     /locus_tag="LP245_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1520851.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(7854..9812)
                     /locus_tag="LP245_003024"
     CDS             complement(7854..9812)
                     /locus_tag="LP245_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL1520852.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(9809..10681)
                     /locus_tag="LP245_003025"
     CDS             complement(9809..10681)
                     /locus_tag="LP245_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL1520853.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(11023..11895)
                     /locus_tag="LP245_003026"
     CDS             complement(11023..11895)
                     /locus_tag="LP245_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL1520854.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            12023..12592
                     /locus_tag="LP245_003027"
     CDS             12023..12592
                     /locus_tag="LP245_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBL1520855.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12659..13396
                     /locus_tag="LP245_003028"
     CDS             12659..13396
                     /locus_tag="LP245_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL1520856.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            13627..14895
                     /locus_tag="LP245_003029"
     CDS             13627..14895
                     /locus_tag="LP245_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL1520857.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            15382..15846
                     /locus_tag="LP245_003030"
     CDS             15382..15846
                     /locus_tag="LP245_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL1520858.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            15830..16459
                     /locus_tag="LP245_003031"
     CDS             15830..16459
                     /locus_tag="LP245_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL1520859.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            16813..18291
                     /gene="msr(C)"
                     /locus_tag="LP245_003032"
     CDS             16813..18291
                     /gene="msr(C)"
                     /locus_tag="LP245_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBL1520860.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            18338..18784
                     /locus_tag="LP245_003033"
     CDS             18338..18784
                     /locus_tag="LP245_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBL1520861.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(18983..19498)
                     /locus_tag="LP245_003034"
     CDS             complement(18983..19498)
                     /locus_tag="LP245_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL1520862.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            19615..20816
                     /locus_tag="LP245_003035"
                     /pseudo
     CDS             19615..20816
                     /locus_tag="LP245_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         6631 a         3703 c         4315 g         6213 t
ORIGIN      
        1 caaggagcaa tttcaaaaaa cagcttctca tgtttgatga atattttgac ttgtgaccga
       61 agagttggta ggagaacacc gtttataaga ggttgtgaca aaagtcttgt cgcaacctct
      121 tttttaacca aaaaagtgca aatagtttac tttaagtaag agaataatta tgatgaataa
      181 aaaaggtgga acaaatagca tactatatat attgaaatga acactgtatg gatgctccaa
      241 cttgatgaag ctaaggagga attcgtatgt cagaaaagga attaatgaag gtagtcggtt
      301 tttatgaagg gttgccgatc gatgatccaa aaagctttat tgatgaaaaa gaacagatac
      361 ctgtacccag ttcacgggat cttctggtaa aagtcaacgc agtatctgtt aatcctgtcg
      421 atacgaaact tcgccaagat aacgggataa gaaatgcttt acgtatctta ggttttgatg
      481 gagtcgggaa agttgttgct gtaggtgacg aagtgcaaaa attttctgtc ggcgatcgcg
      541 ttttttacgc aggtacaaca acaagagcag gaagcaatca agaataccaa ctagttgacg
      601 aacgtattgt cgctcttgca ccaaaaaatc tttcagatga agaagctgca gccttgccgt
      661 tgacctcatt gaccgcttat gaattgttat ttgaaaaatt tggtctaact ccagaagaaa
      721 atgccaatcg cgggaaaaaa atcttagtga tcaacggatc cgggggcgtc ggttcgattt
      781 tgaatcaact agcgcattgg gctggcctag aagtctacgc gactgcaagt ccgaagaatt
      841 ttgaatggct gaaaaaaaca ggtgtagact atccaatcga ttatcatcac gacttaagta
      901 aaagttttcg tgaattagga atcgatcaag tagagtatgt cgctgtatta ttcgatatta
      961 cccgctactt tgatcaaatc aagcaccttg tccgaccatt tggacatgtg ggaacgatcg
     1021 tagggatcaa agagccgtta gatataggtg tttggaaaaa ccaatctatc agcttcgact
     1081 gggagtatat gttcgctaaa acagactata actatgaaat cgaaacgcaa ggagaagctt
     1141 tagcgcacat tgctgcttta gcaaatgaag ggattatccg cagtacattg agcaaggtct
     1201 attcagatgg gatgaatgcg aagaacttga aacaagcaac caaagacgta gaaacaggac
     1261 atatgttagg aaaagtcgtt gttagtggtc cgttcaacgg ataagcaaga atacgccgat
     1321 ttttttctta tttgactttg ataaaaacaa gagcgcatga cagtaatttg ccataagctc
     1381 ttgttttttt atttataata agcgaatcaa cgaaagggaa agaattcctg ccaagacgat
     1441 caccaataag ctttttgaaa gaatagcagc taaaagtgta ggaactgaag ccaaagcatt
     1501 ttcgagattg atctgcggca gatgtccgat attttgggta aatagactgc tgaaccataa
     1561 agcagacata atgacgatcg ggacaaaact taaatactca agcaacggtt gcggtaaatc
     1621 gaattttttc agtaagacaa atggtaggac cctagaaagc caagttgcta aagtacaacc
     1681 taaaatagtc agcaatgtaa actcaaaaga aggcatgttt gatccacacc cccaatccgc
     1741 acccaatcag tgttacaact acaatcacta agttgcttgg gataaaaatc agtccgacat
     1801 ataccagaat caaagtgaga ccaatcagga tcaactgtaa tcgtttagag gtgtttctat
     1861 cagaaatgac ttgaagataa agtaacccga taaacatagc gacgatggcg aaatccaaac
     1921 caaacttttt cggatcagta ataaaattcc ctaaaagtgc gccaacaaga gaagaaccca
     1981 cccacgtcaa ataagaaatc caattagctg tattcatcca acgaaagttt aacttttgtc
     2041 cagtatagtt caatttattc attcccagtg cgaaactttc atctgtcagc aatgtgccaa
     2101 tcagcagatt ttgaagcagc cgatttttct tgaaataagg agcaatcgtc atactcatca
     2161 gaatcattcg ggaattgact agaaaggtcg agaaaacgat ggaaagcaat gggctgtgac
     2221 tagcaagcat gctgactgtg ataaattggg cagaaccagc atagaccagc agggacatca
     2281 acgtgacgac tagtggatga aatccggcag ctttcccaac gataccaaat gcaagtccaa
     2341 taccgatata accgaaaacg gtaggtaacg tgtctttgat cgcagttttt atatctaact
     2401 tttcatccaa taacaaaact cctttagcac gacataaatt ttcataattg tcgttaaact
     2461 tgtgaatatt ctaaattttt aatgagcatt tgtcaatggt gggattgaaa cgtaaagaac
     2521 tagcgggtcg cagatttaca cgtattgttt cggtgggagg aggcgcgaaa aatcttgcat
     2581 ggctacaaat ccaagctgat attttcgatg caacggtcta ttgtttaagt atggaggaag
     2641 gacctgcatt aggcgcaaca atgattgctg cactagggtt agggtggttc gacacacctg
     2701 aaagttgttg tcagaatttt atccaatata cagatgcagc ggaacctctc ttacaaaatg
     2761 tagaaaagta tcataaaatc tatcaacaat gccggaaaat ctatccagca acgaaggaaa
     2821 tttgtcatga cttataaaac aaaacgcgta cctaatagtc aaatgactaa tattgggtac
     2881 gcgttaagtc ttctttactt catcctttgc atgattcgtg tttttaaagc aaggtctgct
     2941 gtatttcttg tggatttagg atggttgtta tcgtttactt gctatttttc attgaaatcg
     3001 tctttcttta ccgtttcttt agttttttat ctattttttt cttttggtta gaaaattctt
     3061 tttcccgaaa gtcttctttc aggattttta tagagtagcg ttttgaataa gaggcgtcag
     3121 tatgatcgac ttggcagacg aaccaagaga acatttgcct tttttctgca tgaggtgctt
     3181 ctgctaataa ttctttccat aaataataac agtcctctat cagaagaagg gttcgttcat
     3241 cctcaggctc ccaatagaat gtttcgagag tagcaatcac ttcattgatc aattcgaatg
     3301 cgggaagata ggcattttgc tgaataagcg attcaactgc ttcttggatg aactttcgca
     3361 tctccatgat gaacttcgct gttttcctgt ttttgttttt cttgataata tgatcgtatt
     3421 tatggatgat agttgttaat ttatctgaat aatttattgc atgaaatggc atcttaactt
     3481 tgaagcgttc gataaagtgc ggatgttcta taagaatctc tgttaaaagc tcccgtacaa
     3541 gagaggaact agcggaggaa acaagggacg agagttcgga aagtgagtag ttggattttt
     3601 ttattggacg ttcttcgtaa gcgaataaga cagcagccat gtgtttgcat ttttttcctt
     3661 ctatggcata tagacaatca caagtcatgt tggtcttttc atcccaagtg atcactacct
     3721 tataatcttc cgtgccagaa actgttgcgg acaagtactt gcttgtatag ttcaaatgac
     3781 ggacaaaacc gtgcagatga tagctgtaac cgcgttccaa aacgttttca ggaaaatact
     3841 caagccaatt attcatctag ttctcctttc atgaaacact tatttatatt tagtataaag
     3901 aaacgtttaa gaaaaaagta gctgatttta catatttgat aatcactttt gctcgaattg
     3961 tcaaaaattc attctccttt tcttttctta gagaatgtga gaaaaagtaa aagaatagcg
     4021 tgttttaaag atggaacttt ttttgttttt tatttatctg acaaaaatga agtgattttg
     4081 ttagaaataa ataattgttc caattgataa aagaggtatg atgtatcgca aagaaaaatc
     4141 caagcagcgt tctgatcagc agtttgaaca acaatttgct ttgtacagta ggtagtaagc
     4201 ggattaacta agggaataaa agatattttt accgctttgt ttacttagaa tctgtcttcc
     4261 ccaaaattta tttttctaaa ggtaaaacat agataggcag ataataccaa ttatccgtta
     4321 cgaaacgctg cttgagaatt ttctttagat ccatacaaca ttttctacat ctgactaaat
     4381 tggttcctga ttcatcaagt aattgacttt ctttgataat atgataaaaa ggcaatcaag
     4441 gaggaagata aatatgctta aagatctgaa ccaattgatc gattacatcg aagaacattt
     4501 gacagaagga ctttcctata aaataatagc cgaaaataca ggaatctctg aatatcaatt
     4561 aaaacgcatc tttacgttta ttgcagggat gtcgctaatg gactatatca aaaaccgtag
     4621 attggctttg gctaatcgcg atcttctaga tggatcaaga gtgacagaaa cggcgtttag
     4681 atatggatat gaaacagtcg aaggtttttc aagagctttt cgtgattggt caggatatct
     4741 gccttcagaa atcagtagat acggcataca aaaatctttt ccacgcttga cattttttat
     4801 tgatgtcaga ggaggaaaat cgatggaatt tcgtatcgaa aagaaagaac agttttatgt
     4861 ggcaggtgtg gcgaaaaaag ttcctgtcaa atttgaagga gtcaatcaag aaatacaaaa
     4921 gttagcgcag acgatcacgg agactcaaag ggaagagatg cataagttag gagatttata
     4981 tccaaatcaa gtaatcaacg tttcttatgg atttgatgga gaccgcttgg aagaaaaggg
     5041 cagtttgatg cacatgattg gctttgctac gacaaaagaa aatccgtacg ctgatttaga
     5101 aatgcttgct atagaagaac acacttgggc catttttcct aataaagggc catttcccca
     5161 aactttacaa gatacttggg ggaaaatcta tgcagaatgg cttccttctt cagattatgg
     5221 gttagtcgaa gctcccgaga tctcttttac aaaatgggga gaggatttca gtaatgttta
     5281 cagtgagatt tggattgcag tgaaagcaaa aaaatagtta aaaaataaaa atatccctag
     5341 aaaaaagagc gtaatcgtgt catttccctt taattttatg taagatgaac ttaatataat
     5401 agaaagggtg ggagaaatgg caaagtatag gatcgaagaa aaaccagatt ttacggtgac
     5461 gggtattggt gtggaattga agagtagcaa tacggatttt gtcggtttgg ctgcagagaa
     5521 acaagcattt gagcaaaaag ttatcggtaa tggaacaata gatgcattga aacaagctgc
     5581 tgaaaatcat tatttcttta cagtcaacga accctataac gggaaaatga tgtactatgt
     5641 cggtgttcaa acgagtcagg atgttccaaa cactacgcga atcatcccat tcccaaaagg
     5701 aacgtatctt gttgtaagcg ctttagcaga atcgcctgaa gaattaagaa atgatttgac
     5761 gaatacggcc tttgggcatg ttttaagaga agtagaagat tacgcctatg ttgggggtcc
     5821 aaatgctgta gtcgaaatgg gagttaccaa cgggaaatat atgggagaaa tctggatacc
     5881 ggtagtcaat aaaccatgat aatatagagg tcgtgaaagt agcgctttga cctgagcatt
     5941 agagaggaaa aatgggaaat agctttccat attttgcatt tttcagaact aatgccgagg
     6001 gtcagctact tgaacaccgt ttatcaagac gtcatgactt cagcgctttg acctgagcat
     6061 tagagaggaa aaaggggcat gacaaggctt ttgtcccccg gagaataaaa gaatttatgt
     6121 agacgattcc gatcagaaaa atgcaggcac agtagagaga attataaaaa tctctctacg
     6181 aggcctgtgt tttctggtct tttttctttt tccaaaacgg ctattttatg tatcagacta
     6241 tcaagtgtga tcttagccat ttcttcttct gcctttttct gcagccgagc gtagctttct
     6301 tctaaagctt cttggatatt cgcaccaacg acgcaatttg gatttgtttt tggatcgact
     6361 tggataagct gtgtattacc ttcgatgctg cgatagacat ctagtaaaga aatctgatct
     6421 ggacttttgg caagggaagg ctgcggtttt ccggtttttg taaagatcaa accggatttt
     6481 ttgagctgac tcatgatttt acgtacattt gctgcatttg tttcgatact actggcaatc
     6541 atctcactag aaagtgatcg ggtatcttga aacatttcaa tataggcaag tacatggatt
     6601 gcatcactaa attgcagaga atacttcatc agttgtcatc ctttcatttt ttttgcttga
     6661 cttatcttac cacactcttt atgataaagg tgtaatttat aaatgtacag ctgtaaatct
     6721 taacaaataa aaagaatagg gagtggcaaa tatgcattat ttagtaacag gagcaactgg
     6781 aggttttggt ggttatgcgc tggaattctt aaaaaagatg gttccacaaa atgaaatcta
     6841 tgtactagta cgtagtgaag aaaaaggaga agcactgaaa gaagctggat ttaatatacg
     6901 tattggtgat tatgatgatt tagactcaat gaaagaagcg ttgaaaggaa tagatcgatt
     6961 gctttttgtc tctggcgttc caggaaatcg tcaagccgaa cataagaatg tagtgaaggc
     7021 agcacaagca gctggggtat cttatatcgc ttatacaagt tttgcagatg ccgatcactc
     7081 gatcagtgta ttagcgccag atcaccaatt cactgaaaaa atgattaagg attcaggtat
     7141 ttcccataca tttttacgga ataattggta tgtagagaat gaattaccta tcattgggca
     7201 ggctttaaaa actggtcaat tcgtttatgc tgcaggaaat ggaaaaacag gttgggcatt
     7261 gaaacgtgaa tatgcagaag ctgcagcaaa agtactagta gaaagtgact ctccagaaat
     7321 cttagaatta tccggcaatc taactgacta tgaagaatta gccaaggcat tagagcgtgc
     7381 gacaggtaaa gagttagaaa ttattgaagc aagtgatgca gcgtttgtcg aaaatctaaa
     7441 agaagccgga ttccctcaag aagcagctga catgttttta gcgatccaac atgatattaa
     7501 aaaggatcag ttagctattt cctctgatga tttagaaaaa gtattgggaa aaccattaac
     7561 ttctcttgaa gcagcattaa aagaaatatt ggatcaggaa taatgtataa agaggttgtg
     7621 aaaaagccga ttagttttga gtatgaagaa aaattttgtg aaaaagctgt tctgcatcaa
     7681 gtaataagaa gagtcaaata aaaaatagct cttcatatgt ttcgtttagc tggacttatt
     7741 accgcggagt tggcaggaga acgccgtttt tattcggaaa aaggagctga gacaagattt
     7801 ttgtctcagc tcctgtttgt ttatcgataa aaaagtctgg ggaagacgat ggctcaggct
     7861 ttgttggaaa cagagccgat tttatcattt gcttttacat cacgtgcggg ttcgatttct
     7921 aagctttgga ctttgtcgcc atttgtgaat acaacgacca tatccgtgtt tttgcctgca
     7981 gattgaatag cggcaagatc aactaaagca atcaattgac ctcttgcgac tttttgacct
     8041 tcttctacat ataaagtgaa tggttcgcct tttaagtcaa cagtgttgat gcccatatga
     8101 agcaagactt cgataccagc atctgtttgg attccgacag catgtttcgt tgggaaaatg
     8161 tttgtgatcg taccagcgat tggagagaag atttctccat tttctggtaa tacagcatag
     8221 ccgtcaccca tcattttttc cgcgaataca tcatctgaaa cttcagtgat tggaatcagt
     8281 ttcccatttg cgatagcgta aatatcttgt tcgatcgttt caccggcaaa tgtttctgtt
     8341 ttaaccacgg tgtttgtttg tgcaggtcgt gctgcagcac caccatgtag ttttgccatc
     8401 tcatctgcaa cgaattgtac ttctgtacct acgatgactt gcgcattttt tccgtcgatg
     8461 atcttcatac caggtacgcc agtggctttg attttatttt gatcgatcag gcctgtatct
     8521 ttgacttgca aacgaaggcg tgtagtacag ttatcgatcg aagttacatt gtcggctccg
     8581 cctaatgcag cgtagatttt gcttgcttgt gccgcatatt tattgtctga attagtcgtt
     8641 gcagtatcgt catctgaaag atctgcttcc tcgcggccag gagtcatcag atggaatttt
     8701 ttgatagcaa agttaaagcc aaagtagtaa atcactgctg ttactaatcc ttggacgatc
     8761 aacatcaatg gctgattcgc aatcggattt ttcaaagata ggaagtaatc gacaaatccg
     8821 gcactaaagg caaatcctgc tgtccaatgg aagaatgcac tcactgctaa agaaatccca
     8881 gtgaaaattg catgcaagac atataatggc caagcaacga acataaatga aaattcaagt
     8941 ggttctgtca caccagtaaa gaatgaagca aaagctgctg ctagcatcaa ggaagctgtt
     9001 tttgctttgt tttctggacg tgcatttctg taaatagcat atgctcctgc tggaagcccg
     9061 aacatcatga ttgggaaaaa tccagcttga tacattcctg ttacgccttt tgttccttca
     9121 gaagccaaaa atttaccaat atcattgatt cctgctacgt caaaccagaa cacggagttc
     9181 attgcttgat gcaatcctgt agggatcagt aaacggttga agaagccata aagacctgca
     9241 ccaccccagc ctaaactcaa aatgaattta gcaaaagaaa ctaaagcaga gtaaaccgga
     9301 ggccatacga gcagtagcac tgcactgatc agcaacatga caaaggcagc caagattggc
     9361 actagacgct tgccgctaaa gaaagataaa gccatcggta attttgcttc gtggaaacga
     9421 ttataaagag ctgccgcaat caatccggca ataataccaa taaatacgtt actgatctga
     9481 gcaaaagatg gatcaactga ttctggtttg atattcaata aagtagctac tgaatcagtt
     9541 tttaaaacat ttactggaac ttcaaatgcg accaaacctg ccaaggcagc agcacctgat
     9601 ttgtccactg acatccctag tgctaaccca acggcaaaca gcaaaggtaa ttgacctaaa
     9661 actgcgttac cgccagcttg taaaaaatga gcgacaatgt cgttactata agatgcccac
     9721 cagtttccga tccctactag taaagcagca gcaggtaaga ccgcaactgg aagttgaagg
     9781 gaacgtccca ttcgttgtag atatgctttc aatttttttc ctcctcatga ttgttaacat
     9841 ttgtttgtac gattgcgctt cttaaacgct cgatatggat ggccaagtaa cccagttctt
     9901 ctttcgtgat cgcgagctgg tattctttgg tcagcaacac acggattttt ttagaaatct
     9961 tatagctttc tgggtatttt cgtttgacca tttctacgat ttccgtgtct aaaacagcat
    10021 attgttgcgc atgggttcgt tgtagaagca gtcgtaaatg attcaccagt cttgaataat
    10081 tcagtgaaaa tggttctgaa tggatatctg tttccaattc tgattccact aaatggatga
    10141 tgtcagatac aatcgtcact tcacggatac tgcgatggtt attgttccga ccgcttcgtc
    10201 cgctgtgaat atggattgcg atatatcctg cttcgtcata agtatatgga atcccaagct
    10261 cttttgtcag atactctact gcccattgag caatactgaa ttcatcactg taaagcactt
    10321 cgatttctct taaaagtttg ttgcggatga cgataccgtt attaatgttc tccgcagaaa
    10381 aagcaatgtg gtcggtcaaa gcgatcaata catgttcatt caacttttcc atcaaaacag
    10441 tttccgcatg atcaatgatc gtttctgctg caaataaaaa gcgttcatca atctgattaa
    10501 gtaaattttg caacttgatt tgaccttctg gttccatgac aaatatccgt tcgacatcac
    10561 gatcaaaaat caaatcattt ctttttctgt caaatccaat cccttttcca atagctactt
    10621 tttcctgtcc accgtcatct accaatactg cattttgatt aaagatcttt ttgattttca
    10681 tgcgcgcacc ctttttgaag atttggtttt cacgtttgct agaccagttg attgcggcca
    10741 aacaaaaata gacacgaaaa acctcctagg gaaaccatgt tcctcagaga tttttcatgc
    10801 ctagtatgat ctagtcacat gaaacgaatt attgttaacg taatcaattt tatatagaca
    10861 gttatgtttt gtcaattctt tttttataat tatagtaatt tactggaatt atcagaaata
    10921 aaaggaagaa ataaattaag aaacttatgt tatttaatcg ttggatcttt tgcttatctt
    10981 attcgttgtt aaaaagctga aagcgaagga aaaaaactct acttaactgt atttctccgt
    11041 taggacatct aaaaatttac gagcagcagg agaaagaggc tggtcttttt tccaaatgag
    11101 attcagtgaa gcttgtaatg gcggatcgag tgggatgaat attttttccg tcccataagt
    11161 attgatgatc ccatctagag ctaatgcacc aaaagtcccg ttatcgacca tcaaagaagc
    11221 attgtacaat aagttatatg ttccgacgat cgataactga tctatgctga aacctagcca
    11281 ttcagctagt tgactgtcca ctgacgtttg ccgggaaatg atcaaaggaa cagttttcag
    11341 ttcctgcgga tggatgacgg tttgctttgc taaaggatga tttcgatgta tcaaaagtcc
    11401 ccaacgatct tgggctggca gtcgaaatga ctggtatttt tgtttgtttg tcggttcgat
    11461 tacgagtcca aaatcaagta atccgctatc cagtttgtct atgatatcat ctgcattccc
    11521 gctatataaa tgaaactgga tatcaggatg cgccttgatc aacgaatgaa ggctatcaga
    11581 aatgaaagag attgctttag tttcgcctcc gccaatgtag atttctccag agatgattgc
    11641 gtcatttgtt aaattgttcg ccgttttttc taccaacgac aagatttctt ttccttttga
    11701 ataaagatat cgaccagaat ccgtcaactg tatctctcgg gagccccgag tgaaaagtgt
    11761 cacaccaagt tcttcttcta aatctttcag ttgttttgag agagtaggtt gcgtgatatg
    11821 cagagatttt gctgctcggc tgatattttt ttctctagct actgctaaaa aatacgtcag
    11881 tatacgaata tccatttttt ccctcctgtt tttaaaaaag cataccacta agtatagtta
    11941 aaaggaatag ttaagtatgt tttataagta ttagacatga taagccgtcc gttataaagt
    12001 aaggataaaa ggagggagca aaatgacaag cctcatcgaa aaacaaatcg tcaataaaga
    12061 gattcgagta acggatccgc tctttgaagt gatccatcag atccaagctg aaaacgaaga
    12121 gcctttagca gcgctgaata ctgggtacca tgaaccagca gatatccgca aacggctaga
    12181 aaatatcatt agtgacaaag tagatgatac ggtgactgtt ctgctgcctt tttatacaga
    12241 tttcggcaaa catattagta tagggaaaaa tgtctttatc aatcgtcaag tgatgttcgt
    12301 tgacttaggt ggcatctgtt tagaagattc agtattgatt ggtcctcgtg tcaacctcat
    12361 cacggtgaac catctaaccg atccaaaaga acgaagaggc ttgtcagtaa agccaatcca
    12421 catcaagaaa aatgcttgga tcggagcagg agcaactatt ctgccaggcg taacgattgg
    12481 cgagaatgcc attgttgcag cgaatgcaac tgttacgaaa gatgtcccag acaataccat
    12541 cgttgcagga atccctgcca aaatcgtcaa acctgtcgaa cggattattt gaacagtaag
    12601 atgaaataag agatagtgag tataagcaag agatttttca aaacaggagg agaatagaat
    12661 gaatgattta tcagaaaaag tgattgtcat catgggcgct tcaagcggaa tcggtgaagc
    12721 aacaacgaag ctattagcag aaaaaggggc taaactagtt atagctgcac gccgagaaga
    12781 tcgcctaaaa gcaataaaag aatctttacc agaagctgag ctatatattc aaacagcaga
    12841 tgtaagagat tttgcacaag tccaagcagt tatcgattta gcgatggaaa agttcggtcg
    12901 aatcgatgta ttgtacaata atgcaggaat catgccaacc gctccattag ttgaaggtca
    12961 ccgtgatgaa tggcaaaata tgcttgatat caacatcatg ggtgtgttaa atggaatttc
    13021 cgccgtactt ccaatcatgg aaaaacaaaa atctgggcat atcatttcaa ctgattctgt
    13081 ggcgggacat gttgtttatc ctgattccgc cgtttattgc ggaacaaaat ttgctgtccg
    13141 tgcaatcatg gaaggattac gtcaagagca acggcaaaat aacatcaaat ctacgatcat
    13201 ctctccagga gctgttcaaa ctgaattata tcaaaccatc agcgacaaaa aggctgctct
    13261 tgaacttcat gaagcgcaaa aagaatgggg attgacctcc gaagatatag cttctgctgt
    13321 agcatttgcg atagaaacgc cagaccggat gtctgtcagt aacatgatta tccgtccgac
    13381 gacacaggaa gtataatcca taacggataa tatccaaaga gaattacttg ttaaatagtt
    13441 attcaaacga ccatcaattt aaggcgtgaa tggagaagaa tattcttcat ttacgtcttt
    13501 ttatgtagaa aaagcaaatt tatcaaaaag aaacaaatgt tatttaaata tggacattga
    13561 cttgctttta cttttttagt tacactgtta tttaggaaaa gtttcataat tcaaaggaga
    13621 aaaaagatga aagcaaagaa tttattattt agcgttattc ttttaggaaa tctagcagtt
    13681 gccaacacaa cagtgctagc tgaagaatcg acagaaactg tcgcaactca gacatcgagt
    13741 tcttcagaaa caggaattga aaacgataca gagagtactt tgcagtcagc tactgtctca
    13801 gaaaatacaa tttcaaccga agaaccaaca actgaaacaa cagaacaaac acaaaccgaa
    13861 gacagtacat cagcagaagc tcagaacaat ccagagaatg cagaagaaat cacgaaccaa
    13921 ttgacagatg ggcaaacatt gacacatacc catcaagcag atttgtctga attcgaaaac
    13981 tatactggct atgcttttta tgctcgctca tctgctaatt ctcaacaagc gttcattgat
    14041 agtattgcct caactgcaca aagtttggca agtgccaatg acttatatgc atcagtcatg
    14101 attgctcaag ccatcgttga aagtggctgg gggaacagta ctttggcttc tgcccctaat
    14161 tacaatctat ttgggattaa aggaagctat aatggccaat ctgttacgat gcctacttcg
    14221 gaatatgtga atgggcaatg gattacggtg aatgccgctt ttagaaaata tccttcgtac
    14281 aaagaatcat tgcaagataa cgtaacggta ttgaagacga cttcttttca gccaggcgtt
    14341 tactactatt ccggtgcatg gaaaagcaat acgaactctt acaaagatgc tacggcttgg
    14401 ctaacaggtc gttatgccac tgcgcctaat tatggttcta cattgaacaa tgtaatcgaa
    14461 acctataatc tgacacagta tgatacagca ccaacttcaa cttctccgat gtatcgtctg
    14521 tataaccgtc atacaggaga acatttatat acattgaatg ccggagaaaa aaattatctg
    14581 ccaactgtag gctgggaata tgaagggatt gcttggcaag caccaaacag cggacaacct
    14641 gtctaccgtt tatacaatcc ttacagtgga gaccatcatt acacaatggc acaatctgag
    14701 atcaactctt taacaaaaat cggttggcgt tatgaaggtc taagttttta ttctggtggt
    14761 tccaagccaa tttatcgact atttaatcca aatgaaaaaa ctggtaccca tcactatacc
    14821 ttgagtgcta aggaaagaga ttggctaaca ccgatgggct ggagatatga aggaatagga
    14881 ttttatggtt attaaaaaga ggtagtgaaa aagctgccct gcatcaagta gtaagaacag
    14941 ccaaacaaaa acagattttc atgttttttg tttggttgaa cttattaccg cagatgcaag
    15001 tttttgaaca ccgtttactc aaaaaaggtt gtgacaacat cttgtcataa cttttttatt
    15061 actgtttaag catactgatc caatttctaa tattcgacgg gattcttgca aaaggcgatt
    15121 tcggaaattt ttggcggtgt aaaattttct actgcagaag agctatcttc tatagtttga
    15181 taagaatcaa taatcttggt tttagcgttg tgctttcttt atcatttttt ccgttcattc
    15241 tacaaaaaat ttcttttctc tatacttttc tattgagagc gtttttttta ttacacagct
    15301 gattctttga cttttttctt tttttattct attattgaca agtcaatcgt tgacgagtca
    15361 attattagaa aggaggaaat tatgtcttta gaagagatta gtcacctttt atatcaaatc
    15421 aaattagccg atcaaaaaat cgtccagatc tttgaagaaa atatcggtat aagtcttact
    15481 agatacgaga tcatgatgag actgaaagaa gaaaatccat tgctacaaag cagtttgcaa
    15541 gaaaagttgc agattgatca aggagcagtt actcgtcatc tgaaggtatt ggaagcaaat
    15601 ggctatgttt cgcgtcagag aaatcctcag aacaaccggg aagtgtatgt agcgctaaca
    15661 gaaaaagccc agaagaaaat cgagcattgt gaaatggacc ataaagatac aggttccgtg
    15721 ctatccccgg ctttcagcga tgtagaaatg aaacaatttc taacactttt agataaattg
    15781 aatacccaac tttgcaatat aacaacagaa acgaaagagg ttaataataa tggaacaaaa
    15841 aaatgatttt tcaacaatta tgactggtag aagatccgtt cgcgtatatg atgaaacata
    15901 caaaatccca cacgaagaaa tgctggaaat gatcaaagaa gcgacgactg caccttcttc
    15961 tgtcaatatg caaccatggc gctttgtggt cgctgaaagc gaggaagcaa aagaaatctt
    16021 gcgtcctttg atccgtttca atacgagaca aaatgatact tcttctgcaa tggtcatgat
    16081 ttttggcgat atgcaatgtt acgaatatgg cgaagaaatc tataaccaag cttacgaatc
    16141 agggaagatg ccaaaagaag tcagagatca acaattagct gcgatcattc cttattacaa
    16201 gagtttttca agagaagaaa tgaacgatgt agtcaaagtc gattctagct tagcggctat
    16261 gcaattcatg ttagttgcgc gtgatcatgg ctatgaaaca aatccaattg gtggattcga
    16321 agcagatcag ttggcagagg catttggttt ggataaagac cgttatgttc cagttattat
    16381 tttatcaata ggaaaagcgg tagaagaagg ttacgagtct gttcgtttag caccagaaaa
    16441 gatcactacg ttcgaataaa aggttttcag ttactattca gtagctattg ctttttttga
    16501 atcgtgtgtg gtaacctaat aaaaaaggag gtcggaaaaa tgactgcatc gatgaaatta
    16561 cgtttcgaac ttttgaataa caactaaata aattcaaaag acatgtataa acaacaattt
    16621 catggatgga gtatgtccat tttttcgaac gacagtagaa taggtgaaag ctatgacaga
    16681 tttggtgatt tagtcatagt tatttcgttc agagtaggaa aagatgtgat gcagtttttt
    16741 tgcaaacaga tttttctgct cttttttagt atcgataatt gttgttttac atgaaatagg
    16801 agtgtaaaac atatggaaaa tttagcagta aatataacaa atctacaagt cagctttggc
    16861 aaccagctag aactatctat tgattctctt cgtgtctatc agcaagatcg tatagggatc
    16921 ataggagaaa atggtgtcgg taaatcgact ttgctcaaac taatagccgg tgaacttttt
    16981 cccgatcatg ggaaaatcca aacagagatc accttcaact acctgcctca attaacctat
    17041 ctcgctgaag caaaggacct aaatttggaa ttagccagtc atttccagtt aagactggaa
    17101 gaaacttcag agcggaaatg gagcggaggg gaagaacgaa agatcgagtt gatacgtctt
    17161 ctttcttctt atgaacaagg gatgcttcta gacgagccaa caacccatct agatagaaaa
    17221 agtattgatc gactgattga agagcttcgt tattattatg gtacgctggt ttttgttagt
    17281 catgatcgct attttctaga tgagctagca tcgaaaatct gggaagtaaa agacggagaa
    17341 atccgagagt tttcggggaa ttatagtgcc tatctcactc aaaaggaatt ggagaaaaag
    17401 actcagctac gagaagcaga gtcgatcatg aaagagaaaa aacgattgga aaaatcgatc
    17461 caagaaaaga aaaaacaagc ggaaaagttg gaaaaagtgt ccagtaaaaa gaaaaagcaa
    17521 caaatcagac cggatcggtt gtcttcctct aaacaaaaag acagtgtaca aaaagccatc
    17581 caaaagaatg cgaaaacatt agagagaaga ctccaaaaaa taggagaaac aaccaagccg
    17641 cagcagatga aacaaatccg ttttccagta ccaaaatctc ttgaactcca cagccgctat
    17701 cccatcatgg gacaaaatgt ccaattggaa agaagtggga gaacattact ggtaaatggt
    17761 gattttcagt tttctttagg taaaaaaatc gcgattgtcg gtgaaaatgg ttcaggtaag
    17821 acaaccttat tagaacatat ccgcaaacaa ggagaaggaa tccttctctc tccgaaagta
    17881 agctttcaag tatatcagca aaagggttat caaatgacat ctgaagaatc catcattcgt
    17941 tttgtcatga gacaaacaga gttttcagaa tcgcttgtcc gtagtttgct gaatcactta
    18001 gggtttgctc aggaaacttt gacgaaaccg ttatgtacat taagtggggg agaagcgacc
    18061 cgtctgacga ttgctttgct ttttactaag ccaagtaatg tgttgctgtt agatgaaccg
    18121 actaatttta ttgatatggc aacgatcgaa gctttagaga agctaatgca aatatatccg
    18181 ggaacgattt tgtttacttc tcatgattct tactttgtcg agcgtacggc tgatgaagtt
    18241 tatgaaataa aagggcagaa aataaaaaaa gtacttacga gaaattttta aatgtgctac
    18301 gatgattttc gtgacaaatt taaaggagtg gtacagattg cctacaaata aaaaagaagg
    18361 aataattttt acaacaatga tgtgtttttt gatggtcttg gggatgagcg cgtataattt
    18421 atggctgcat caagatcttc atttatcaag tttgttgatt ggtctagtgc ctggattcgt
    18481 ggtggctttc attttggatg tcttcatcat cggtgtgctg gcgaaaaaaa ttgcctttaa
    18541 actaccagta aatccagaaa gcaaggtcca aatgatctta actatttcat gcttgatggt
    18601 tttaggaatg gtgacatgta tgtctttatt cggtgtgatc atggaacaag gaatacctga
    18661 tcaattattc tctgcttata tgaatgcttg gaaaatgaat gtgattgccg ctttaccgtt
    18721 gcagttgatc atcgttggcc cgctttcaag aagtgtgcta aaagcaattc aaagtaatga
    18781 atgatggaac actgttattt gaaaaaaggc cttggcatgc tttttgtcat agtctcttga
    18841 atgcagttct agaaaaatag tgatccgaac gataggtttt ggcctgtcgt tcggatcgct
    18901 ttttcttttc caactgtatt gctcttttat tgaagataat ttgctcttca atagatattt
    18961 ctagaaaggt tctgtttatc ccttactcaa aaaactgctg catttgttct cttacttgct
    19021 gacaccattg gagttcctgc tgacaaagca taattctgcg ctggatcaca acataacgtc
    19081 caaattcttg tttcttgtct agcgagaggt cattcaattt tttttgattt ttttgcatga
    19141 ttttgttcag ctgttgttct ctagtgaata gcagtccagt agctgttgtt ttatcgagcg
    19201 tcgaaaaagc atagattttt gctagaaatt catctttttg cgtaggagcg ggagtttcct
    19261 ctttgatcca ttcctctaca agagcacgtc cttcatcagt caagtggtag atcttttttt
    19321 gagagtgctc gtctttgtcc aaaacggtca cataaccctg ctggtctaac ttggcaagcg
    19381 ttgtatagat ctgactgtga tgggcttccc aaaaaattgt gatcagctgc ttcaattcat
    19441 acccagaacg tggtttggat aaaagcacgc ataataatat ataggctaaa gtattcataa
    19501 aaatcctacc tctcgtctta ttttctttat tatatcacag taaagtttcc acgttttaca
    19561 tgtgcatatt tacatgtaaa ataaatcatg tatgatgcta atagagagaa agggatggaa
    19621 atattggaga atcaaataga tatacaagaa caaacaaatg aagaaacaaa ggggaaaagt
    19681 tcagcgctag ttgtagcagc tacctgtatg atcgctttta tgggagtggg tctagtagac
    19741 ccaatcttaa aaacgattgc tgcacagtta aacgctacgc cagctgaaac gaccctgtta
    19801 tttactagtt acatgttagt cactggtgtg gtgatgctat ttacaggttt cttatctagt
    19861 cggatcggtt tgaaaaaaca ttgatgacag gattgtttat catcgttgta ttcgctggtc
    19921 ttggcggatt atctgggaat atcggaatgc tgattgggtt acgtgccggc tggggtgtcg
    19981 ggaatgcttt atttgtctct actgctttag caacgatcgt cagtatttta gttggtaaca
    20041 cagaaaaagc aatcatgatg tatgaagcag cacttggctg cggaatggct gttggccctc
    20101 tagtcggtgg ggtcttgggc agtggttcat ggcgttatcc attttttggg gtagcatttt
    20161 tgatgttttg cggttttata gccctagcgg tacttttacc tgaaactgag aaaccaaaga
    20221 gaaaagtagg cctttgggaa ggtgtcaaag cgttaagcaa tcataaactt cgttcagttg
    20281 gactaatcgc attgttatat aatttcggat tctttacttt acttgcgtat gcgccatttt
    20341 tattgattgg ctattctgaa ttagaagtcg gttttgtatt ttttggctgg ggtgtgcttc
    20401 tggctattgc ttcgattttc gttgcaccgg ctcttgagcg gaagtttacg acttatcgga
    20461 caattttagc agcatttgtc ttattcatta tttgtttgct gttattagga gctggaactt
    20521 ctatgccagt ccttgtaccg atcagcattg tgttagcagg atttttccaa ggaattatca
    20581 atacactgtt gacgacgatt gctatggaaa taccaggtct gcaacgaaac gttgcttcgt
    20641 ccagctatag ttttgtccgc tttttcggtg gagctttagc accatttatt gcaggtgtga
    20701 ttggtgaaca tattggtgaa agctatgcgt tttattttgc aggtgccatt gttcttatca
    20761 gtgtatgttg tatcatttat caccgtaatt attttgctac aaatgaagaa gaataagaaa
    20821 tcagaggttg tgaaaaagct gtcctgcatc aagtcataag aa
//
LOCUS       DAFEEZ010000195        18009 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.guided.059, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000195
VERSION     DAFEEZ010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.guided.059"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..324
                     /locus_tag="LP245_003036"
     CDS             <1..324
                     /locus_tag="LP245_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBL1520863.1"
                     /translation="SRGILELLREGQQGVTLRTFESMYFQKKLVTDNQAIAHYHFYRP
                     ENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKRFITNDSTIYEQYEYDLS
                     SVENK"
     gene            complement(474..1415)
                     /locus_tag="LP245_003037"
     CDS             complement(474..1415)
                     /locus_tag="LP245_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL1520864.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            1541..2662
                     /locus_tag="LP245_003038"
     CDS             1541..2662
                     /locus_tag="LP245_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL1520865.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            2920..4422
                     /gene="eat(A)"
                     /locus_tag="LP245_003039"
     CDS             2920..4422
                     /gene="eat(A)"
                     /locus_tag="LP245_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBL1520866.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            4450..5016
                     /locus_tag="LP245_003040"
     CDS             4450..5016
                     /locus_tag="LP245_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL1520867.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            5227..6288
                     /locus_tag="LP245_003041"
     CDS             5227..6288
                     /locus_tag="LP245_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL1520868.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6291..7187
                     /gene="murQ"
                     /locus_tag="LP245_003042"
     CDS             6291..7187
                     /gene="murQ"
                     /locus_tag="LP245_003042"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBL1520869.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7201..9183
                     /locus_tag="LP245_003043"
     CDS             7201..9183
                     /locus_tag="LP245_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL1520870.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9248..9694)
                     /gene="nrdI"
                     /locus_tag="LP245_003044"
     CDS             complement(9248..9694)
                     /gene="nrdI"
                     /locus_tag="LP245_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBL1520871.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            9905..11329
                     /locus_tag="LP245_003045"
     CDS             9905..11329
                     /locus_tag="LP245_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL1520872.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(11510..12283)
                     /locus_tag="LP245_003046"
     CDS             complement(11510..12283)
                     /locus_tag="LP245_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL1520873.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(12280..13185)
                     /locus_tag="LP245_003047"
     CDS             complement(12280..13185)
                     /locus_tag="LP245_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL1520874.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(13339..13659)
                     /locus_tag="LP245_003048"
     CDS             complement(13339..13659)
                     /locus_tag="LP245_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBL1520875.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            14133..14819
                     /locus_tag="LP245_003049"
     CDS             14133..14819
                     /locus_tag="LP245_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBL1520876.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            14821..15765
                     /locus_tag="LP245_003050"
     CDS             14821..15765
                     /locus_tag="LP245_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBL1520877.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            15964..16608
                     /gene="pcp"
                     /locus_tag="LP245_003051"
     CDS             15964..16608
                     /gene="pcp"
                     /locus_tag="LP245_003051"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBL1520878.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            16687..17964
                     /locus_tag="LP245_003052"
     CDS             16687..17964
                     /locus_tag="LP245_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520879.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         5752 a         3195 c         3847 g         5215 t
ORIGIN      
        1 tcgcgcggga ttctggaact gttgcgggag ggtcagcaag gagtgacttt gcggacattt
       61 gaatccatgt attttcaaaa gaaactagtg acggataatc aagcgattgc tcattatcat
      121 ttttatcgtc ctgaaaatat ttttttgctt cgagaacgtg atttagatga attaccggaa
      181 tttctgcata caccatttaa gccaatccta tcagagctat tggaatttta tgatgcagaa
      241 aattgggcaa aacgatttat cactaacgat tccactattt atgagcaata cgaatatgac
      301 ctctcctctg ttgaaaacaa ataaaaaacc tacattttga agagattatg tactgaaaca
      361 aacaagcaca attcttatgg catcatgaga gttgtgtttt ctttttgatc ttttattggg
      421 cttaaaaaaa gagaaccagc tgctgattca gctgattctc atcagagagc cttttattct
      481 gcgccaagga ttccttcttt tgcatggact aattgggtca aaaaggcaca atatggtgta
      541 gcaatatcat atttttgtcc ttttcgccaa atggcaccat tgatgtagtc gatttcagtc
      601 aaacgatggt ttttgatcag gtcttggtac atagatgggt aatgcaaccc gatgttgtca
      661 ggatcataag tagaagcaat atgttggtac acttcttctt gatctagtat gattccttct
      721 tttgctgcga tagaagcaaa ttcagatacg attgttcgaa ccatgctctc tgccgctttt
      781 tgcgcgccta gttcagcaat attacaatcc aaaatcgtgc ataaaccatt caatgttcca
      841 tttacacaag cttttcgcca aatggaataa cgaacgttat ggctatagat cggatttaaa
      901 tttgcttctt gaaagacttc tacaactttt tttgtaaatg cttcgccttc tggttccaag
      961 ttctctagtt cgatttctcc atcacctaac aatgtgactt ttccgggacc agctagacca
     1021 gctgtccaca tcgtgatccc aaataagata tttttctttg gcacatattt ttccagtaca
     1081 tcttcatgac ctaatccatt tagtaaacac aaaacataag tattgtcagt aataatggat
     1141 tggatcgaac aaaacatatc atctaattga ttggcttttg ttaatgctac gatcaagtcc
     1201 acgtgttcgt tgctttcgat gatttcttct ggtgaataga ttggcagttt tgcgaccact
     1261 tctttaccgt taaagtcagc aatcaaccca tttgtacgaa tggcttcaat gtgagcaggc
     1321 caacgatcga tcaagaggac ctcatttccg ctttgatgta gcatcaatcc gattcggctg
     1381 cccattgctc cggccccagc tattgcgatt ttcatgtttt ttctctcctt tattcaatga
     1441 gttccctttt agtatataga aaaatggaag aaaatagcat tgttttgttt gaaaaaaatg
     1501 aaaaaaagtg tcttacttaa gaagaaagtg agggatacag atggatattt tggcggcaat
     1561 tgattcattt aaaggaagtg cttcttcatt tgaactaaat caggcagttc taaatggctg
     1621 ggaagatcgt aaaggaagaa aaatcaatgt gccgattgca gatggcggag aaaatactgc
     1681 agaagcaatc tattacgcgc tcaggggaac atggcgtacc attgatggga tggatctctt
     1741 attccgtcag cgaaaaatca gctatttatt gacaacttgg caaggaaaaa acaccgcagt
     1801 catcgaatct gcacaagcat tggggttaga tctacttgat aaaccaacgg atcaaactat
     1861 ccgacttgct tccagttatg ccttaggaga acttattaaa gatgcactgc ttcaagaagt
     1921 agaacaaatt attgtcactt taggaggaag cgggtgtagc gatggtggtc taggattact
     1981 ccaatccttg ggtgcttctt tagaagggta cacagaagga aatcctttat tatctactaa
     2041 aaaacttcat tttgatcgaa gaaacgttct tgtttctaaa gtaaaattga ttatcgctgc
     2101 agatgttacc aatccatata caggtcaaca aggagctgct tggcaatttg gaagacaaaa
     2161 aggaggaata gatacgacgc tagctttctt agataaacaa gcaggaaaga ttgctcagca
     2221 aataaaagat ttctgggagg tggatttaga tgatattcca ggaagtggag cagcaggcgg
     2281 tattggtgga gccctttttt tgttgggagc gaagatggtt tctggtttcg atttagtcag
     2341 ccaaatcact ggattggaaa aaaagatcga acaagcagat gtcatcatta caggagaagg
     2401 gcggatcgat cagcaaacga tccacggaaa agttccatac ggtgtagcag tgcttgcaaa
     2461 aaaatatcga aaaccaataa tcgctatttg cggaagtaga gaccaagagc tagaaggact
     2521 ttctgatttt ctcccaattg tcttaagtat tcatttgggt ccaataggtt tagaagaagc
     2581 aatggaacac aggcaaacat tagaaaaaac aaaaatctta ggacagacac ttagcagatt
     2641 tttcaccatc ctcccgaagt agttgacaaa atcattttct ttatgctatc gtaatttcaa
     2701 atataggaca aagtgaggga tccgtgcatt gaaaaattaa gtcgattgat gaaagctgca
     2761 ttcagactgt accttgtgga gacaaggaag cagtgtgcag attttcggga ttggcttggt
     2821 tttttcgatg tatgggtctt tttgtgtgta tccaaccctt gcatcctctt tagccagttc
     2881 tgaaaatagg actggtcttt ttttacgagg tgatggaaaa tgtctaaaat cgaaataaaa
     2941 aatctgacat tcggctacga cagccaaggc acattattat ttgaacaagc aaatctaaat
     3001 tttgacacac aatggaaact aggacttatc ggacgaaacg gtcgaggaaa gacaacttta
     3061 ctgaatattc tacaaaacaa actaccttat caagggcaag taatccatca gcaagaattt
     3121 gcctatttcc cgcaacagac aaaagataaa gaacgtttaa cctattacgt gttaaatgat
     3181 attacggatt ttgagatatg ggaaatcgaa agagagctcc aattgatgca aacagatcct
     3241 gaaatcttat ggagagaatt cagcacacta tcggggggag agaagacaaa agtcctactg
     3301 gcacttttat ttgtggatga cactcatttc ccgttaatcg atgaaccaac gaatcatttg
     3361 gatatctctg gtagaaaaca agtagcggct tatttgaaaa agaaaaaaca aggcttcatc
     3421 gtggtcagcc atgaccgggg atttatcgat gaagtagtgg accatgtttt agcaatcgaa
     3481 aaaagtcaac tggaacttta tcaagggaat ttctctatct atgaagaaca gaaaaaactt
     3541 cgtgatgaat ttgaaatggc tcaaaatgaa aaattgaaaa aagaagtcag taggctaaag
     3601 aaaacagcag ctgaaaaagc cgaatggtct cgttcccgag aaggagataa aacaaagaaa
     3661 caagtcggat tcatcgatac tgaatctaga cgagtgaata aaggagcagt gggtgctgat
     3721 gctgcacgga cgatgaaacg atccaaagca atcgtgaatc ggatggagac ccagatcagc
     3781 gagaaagaaa aactattaaa agatatcgaa tatatcgatt ctttgacgat gaatagccaa
     3841 gcgtctcacc ataagcgact tttaagcgta gaagatcttc aattagggta tgaaaatctg
     3901 ttattcgagc caattcattt tacaatcgag cctcatcagc gggtggcgat ttcaggtcct
     3961 aacggtgcag gaaagtcatc cattatccat tatcttctgg gggcattcaa cggcaaggtt
     4021 ataggagaaa aataccagcc aaaacatctg agcattagtt atgcaagcca aaattatgaa
     4081 gacaatcgag gaacgttggc ggaatttgca gagaaaaacc aagtagacta ccaagcattt
     4141 ttgaacaacc tccgaaagct tgggatggaa agagatgttt ttcataacaa gatcgagcag
     4201 atgagtatgg gccaacggaa aaaagtggaa ttggctaaat ctttatcaca gccagctgaa
     4261 ctatatacat gggatgaacc attgaattat ttggatgtct tcaatcaaga acaattagaa
     4321 caactgatct tgaacgtgaa acctgccatg ttactagtgg aacatgatca aaccttcctg
     4381 gataaagtat ctactgagat tatttctctt gagagaatct aacccttgta atctcaagaa
     4441 caacaaggta tggttaaggg gaactttgcc aacgaaggag agaatcacat gctttatgta
     4501 acgagacacg gagaaacaac ttggaacgca caaggattag tttgcggacg ggcagatgtg
     4561 ccgctgactg aaaaaggaca gatgcaggca cagaaactag cagaaaaggt agtagatttg
     4621 cctgttccaa tcacgaaaat catccattcc cctcttcaac gagcaagaga tacagcacaa
     4681 gcagttgctg atcgtctcag cttgccgctg accgttgatg aacgattggt agaaatggat
     4741 tttggggatt atgatggact gccaagcaaa gatgagaact ttcaaaaagc acgtttagcg
     4801 ttcgctgtac gattcccaaa tggggagtca gtcttagatg tgtatgcacg gatcgttcct
     4861 ttattgaaag aatgcatcga agacgaagaa aatgtctatc tgttagtttg ccataatgcc
     4921 ttgataagag tgatcaatgc ttattttcat ccgatgccta atgaggggtt ctttacattc
     4981 atggtagata atacagaatt ggtttcttat gagtaattat gtttttgtgt tatttaaata
     5041 aaatatttca aggcactgct tttgcttagc agtgcctttt ttaggttatg acaattcttt
     5101 tgataatata aactcaacct ttagaaatga aatttaatta ttttaataaa agtattgaaa
     5161 ttttgtttct ttagatatat actctagtca tagaaatgaa gacggataca gaaaaagagg
     5221 gataatatgt ttggcttttc aatatttatg aacgattctt tgtcagaaga gaagaaacag
     5281 tatatccgcc aaatggcatc caatggcttt gtcggtattt tcacttccat gcatatacca
     5341 gaagatgatg tttcggcata tcaaaagcga ttgatcgaac taggaagcga agcgaaaaag
     5401 aataaactag aattgatggt cgatatttca ggagaggcat tggaacgagc gggtttttca
     5461 ttagaagatc taacgccttt gaaagcaatt ggtgtaacag gtttaagaat ggattatcat
     5521 atttccaatc agcagattgc cgactggtca catcaattga aaatcagttt gaatgctagc
     5581 acgatcacgc ctaaagatat cgatgaattg aaagaagcag aagctgattt ctcacagatt
     5641 gaagcttggc ataattatta tccacgtccc gaaacagggc tggacaaaga atggtatcag
     5701 aaaaaaaatc aatggctcaa aattcaaggt ctccttgtcc aaggttttgt accaggagat
     5761 acagagttga gaggcccact atatcaagga ttgccaactt tggaagaaca tcgagggatc
     5821 catcctcttg caggcgctct agatctatta gcaagtaaca cggatattgt ttacatcgga
     5881 gatgcaggtc tgtcagaaaa cgttcaggag caatttgctt ctttccaaaa agaacagaca
     5941 gtcttgctcc atacggaacc tgtagatgaa gaattttacg aatatatatt agggaagcat
     6001 acgaatcggc aagacgatgc aagagatgtc atacgaagcg tagatgcacg ttttcgagag
     6061 attccgccta tcccagcaag aaatacagct acgcgtatga aagggtctat tactttagat
     6121 aacgaaaagt atttgcgcta tatgggtgag atccaattaa ccaaatatga tttgccagcg
     6181 gatgaaaaag tgaatgtagt agctaaagtt atcaaagaag agctaccatt gatcaaccaa
     6241 atcaaagctg gtatgaacta tcaatttata agaaaagaag gaagataaaa atgagcaaaa
     6301 tcaatttaga gaacctaaca acggaacgca gaaaccaaga aacttttgga ttagatgaga
     6361 tgagtatttc tcaagccgtt caactaatga acaaagaaga tcagaaagtg gccgctgcgg
     6421 ttgaaaaaga actgacaagt atcgaaccag tgattgctaa cacgattgag tcctttaaaa
     6481 aaggtggacg tctgatttat atgggagccg gaacaagtgg aagactaggt gtgttagatg
     6541 ctgctgaatg cgtaccgaca ttcggtgtag aaccggaaat ggtcataggt ctaattgctg
     6601 gtggagaaga agcaatgact gtagctgtcg aaggggccga agattcttat gagctagggc
     6661 aagaagatct aatcaagctg aatttgacaa aaaatgatat agttattggt atcgcagcta
     6721 gcggtcgtac accatatgtg atcggtggat tagattacgc aaaatcgatc ggtgctgtca
     6781 caggaacgat ttcttgcaat aaacaagccg aaatcagtaa acacgcggat ttcccaatcg
     6841 aagtcgatgc aggtccagaa tttttgacag gctctactcg attgaagtca ggaacagcac
     6901 aaaaacttat cttgaatatg atttctacta tcagtatgat tggtataggt aaagtattca
     6961 ataacttgat ggtcgatgtc aaaccaacaa atgaaaaact aatcgaacgc tcaaaacgaa
     7021 tcatcatgca agcgacagaa gctgattacg aaacagctga aaagtacttt gaagaagcag
     7081 atcaaaatgt taagctggct atcgtcatga ttttgacaaa tagtgataaa gaggaagctc
     7141 aagcaaaatt agctgaagca aacggatttg taaaagggac cttatgaggg ggaaaagacc
     7201 atggcaaaaa acgaactgac tttggaagaa ctggcaaaac aaatttataa aggggcaggc
     7261 ggcatgggca atgtagaaag cattgtccac tgcatgactc gtgtgcgtat gaagatcatc
     7321 aatgatgatc ttgtaaatgt ctctgaatta aaagcgattc caggagtgct tggtgtagta
     7381 gaagatgaac agcttcaagt catcatcgga cctgggaaag tgaacaaagt agcacagcaa
     7441 atggttgatt tggcaggcgt gaaattagga gaaaaacttt cttctgtaag tacagctaca
     7501 gcaaattcat cagcatctgg aaaagaccgt gtaaacgaac gggcacaaga aatgaaagcg
     7561 gcacaaaaat cgaaacaaaa accatctaaa atcaaatcgg tattaaaaga catttctaat
     7621 atctttgtgc caatgattcc tgcatttgtc ggtactggga tcgtggcagg gattgccgca
     7681 gttttagcaa acttagtcac agccggaaca cttgatgcag caacatggca acaatatatc
     7741 gatgtgatga acatcttgaa aaacgggatg tttagctacc tagttatcta tacaggtatc
     7801 aatgctgcac aagtttttgg tgcaacacca actcttggtg gagttatcgg ggccgttgtg
     7861 atgctgacag ggatgaatcc ggaagcacca ctgaaaaact tatttactgg tgaagctctt
     7921 gcagctggac aaggtgggat cctaggtgtc atcttcgctg tttggctatt gtcaatcgtt
     7981 gagaaaaaac tgcataaagt agtacctgat gcggtagata tcatcgttac accaactctt
     8041 tcattgattg ccatcggtct gattgaaatt ttcttcatca tgcctttagc aggtttcatt
     8101 tctgatggca tggtcggtgg gatcaactgg gtacttggcg ttggtggagc atttgccggc
     8161 ttcgttctag gcacattatt cttgccgatg gttatgttcg gactgcatca aattttgact
     8221 ccaatccatg tgcaaatgat tgatgaaact ggtcgtacgc tattgcttcc aattcttgcg
     8281 atggctggtg caggacaagt gggtgcagca ttggcattat ggattcgctg caaaaaagat
     8341 aaagaattaa cagaaatgat caaaggagct ttaccagtcg ggatcctagg aatcggcgaa
     8401 ccattgattt acggagtaac attacctcta ggacgcccat ttattactgc ttgtatcggt
     8461 ggaggtatcg gcggggcagt gatcggaatg atcggaaatg tcggggctat cgctattgga
     8521 ccttcaggag ccgctttgat cccattgatc tctgacggta aatggttagg ctacatcctt
     8581 ggattattgg cagcttatgc tggtggcttc gttgctacat tcttcttcgg tattcctaaa
     8641 gaccgtttag aaaaagaaga attagcgact gaaacagcca cagtaaatga agtgcctgaa
     8701 aaagtagtac ctcaaacttc agctgaaagt gtgactatcc tctcatcagt tgctgacgga
     8761 acagttgttt ctttagataa agcaagtgat ccagtttttg cacaaaagat gatgggtgaa
     8821 ggctactttg tagaaccaga aaacggacat atctattctc cagttactgg ggtagtcagc
     8881 tctgtcttcc caacgaaaca cgctattggg atcacaacgc caaatggttt agaaatcttg
     8941 cttcatatgg gaatcaacac agttgactta ggcggtacgc catttgatgt gaaagtaaca
     9001 gaagggcagc aagtgacacc tgatacgctt gtagcagaag ctgacttaga agcgatcaaa
     9061 gcagcaggca aagaaacatc catgatcgtc ttggtaacca atatggatcg tgtaaaaaac
     9121 tttgtcttgg aaaaaacagg taaagcaaaa gcaaaagcac ctgtgatgga tgtcaaagct
     9181 taatatgata gaaacaatag aaacgaaaga agaaactgaa atctattttt cagcttcttc
     9241 ttttttatta tttattgttt tctgctaaaa tctgataaat tcgtgtcaca tcagatggtg
     9301 ttccccgtaa ttcataatct gccaagaaag gaaagccaaa tgtttgtgca tattgtttgg
     9361 ctgttagaca atactgatta ttgaagtttt tatttccgct accgactaca ccaagacaaa
     9421 gtttatgatt gtcttcatgt tccagatatt cacgcatcgt ttcggtcaag atttctgtat
     9481 caccgttatc taaaccattt ccgccgtcta aataagtagg aacgaaagta aaaaatggtt
     9541 ctgtttcttt cgtaaaatca ctattttcat ggatttcttt taaagtaact tcaggattga
     9601 caggatcttc tgcatgcatt ttttcagcat attctgctag atgtttggca aaggcacgcg
     9661 tatttcctga aatcgatata tataaaatgt tcatggatca tcctccaatt ctttcctttt
     9721 agtatagcat cttttttaag ttttttggtg gtgtaatttg gaaagggact aggcgctttg
     9781 cttgtataat gagaaaaaag ccggtagaat tatatttcta ttaaagtttt tattaattaa
     9841 gtaaaaataa aaaaggtttg ttatactttt tgataaaagc ggttttattt tggaggatgc
     9901 ttacatggat acagagcaac agaaaaaagg aattggttta attccacttg ctgccttagt
     9961 aattggttca gcgattggag gtggcgtatt tggtattatg acggacatct ccggatcggc
    10021 tggcggccca gctattttca gttgggtact cgtaggaaca gcaatgttga tgctctcctt
    10081 gtcgatcaat aatatcaata aaaaacgtcc agatttaaaa ggcgggatct ttagttacgc
    10141 agaagaaggt tttggccgtt tcgctggttt tatcagcggt tggggttact ggctcacatg
    10201 ctggttaggc aacgtagctt ttgcaacatt gttgatgagc gcattaggat atttcttccc
    10261 agtatttgaa ggtgggcaaa atctggcatc gatcgtgatg agtacagtct ttttatgggg
    10321 atatgcatgg ctagtgaatc ggggagtcga aaatgctagt ttcgtcaatg ctatcgtcac
    10381 attctgtaaa ttagtgccat tatttttatt tattgtagta gctatcagca cgttttcgat
    10441 ccaacaattc attgataact tttctagcga cattatattg aatgcgaatg gacagccgat
    10501 cccgttttcc agtcaagtat tgagttgcat catggtgatg ctttgggtat ttgttggtat
    10561 tgaaggagcc tctgtcgtag gttcacgagc aaaaaaacaa tcagatgttg ggaaagcaac
    10621 gattctaggg atattcggct tgattattat ttacgtcttg gtttccatgc ttccatatgg
    10681 gacaatgacg atgaatcagc tgcaaacgat caaggcgcag cctgctatgg gctatgtgtt
    10741 tgaaatgatg gttggtaaat ggggagcagt cgtgatcaac ggcggtttga tcatttcttt
    10801 agttggtgtt tggctctcat ggacgatctt accgattgaa acaatgggaa acatggctga
    10861 agacggactt ttgcctaaag catggggaaa actcaacaaa aatggggcac caacttatgc
    10921 tatcgtattg acgacgttat gtacgaatgt ctttttactt tcattattat tcactgacag
    10981 tgcttataac tttgcttaca cacttggtac agcagctatt ttcttcacgt ggcttttctt
    11041 aggattgtac caaatgaaac tttcttatca gcggaaagaa tgggtccaat ttttagtagg
    11101 gcttttagca agtgcctttc aagtatgggc tatgctagtc gtagccttta atgaagtaat
    11161 gcttgttctt gttcttttct tgccaggcat ttatttttac ctcaaagcac gtaaggagca
    11221 aaacgagcct gtacaacata tccacttaga taagatttta cttataggtg tgacgatggt
    11281 cggagtgatt gcaatggttt tatttgccac tgggatgctt cacgtataga agtataaaag
    11341 aagtataaag agaggttgtg agcctgtcgt ttattcaaaa acatactagg aaaggagctg
    11401 tgacacaaat gttgtcacag ctcctttttc agaataaacg gtgtttaaga gacagccaat
    11461 cggcaataag gctgaacgtc tctttcacag cctctttttt gatgagtcat catacatttt
    11521 ttcgcttaaa tacgagatat cctaatgcta agaacaaaac gatgtaagct aaattaccga
    11581 atagcatttg attagtagaa agatgagtca attgcttcat gatctcttcg tttccaattt
    11641 ggttttgcag attcaacata ctgatcggat tccatttgat ccactcccat ttttggatga
    11701 gtgcaataag gataccagat atgattgacg aagcaaaata aaagacgatt cctgctgaga
    11761 tggatgcgcc ggaactattg ataaagcaag caatcatcaa cactaaactt aaaatcagcc
    11821 ataaaccgat ataactaccc aaagtataag tgaacaagct ttggatcagt gtttgaccag
    11881 tagaaacctt ctccgtgaag gaaatcgaag ggaaaagaat cagtttcatc aacacagtga
    11941 caataatagc taaaaggtat aaataaacag aataaataac taatgtgatc catttgctta
    12001 ctaatatttc tcctcgagaa tactttcgat aaaggagatt tttcaatgta ccatattgtg
    12061 cttccatcga aatgatcgtg cttgcagctg caatcatgat aaagacaatc caagatgtgg
    12121 cactaaaaag ctgagcagtc atttcaactg gatcaatgat cgtcgtgtat tttttggcta
    12181 gaagtgctgt tcctatgagc aaaacaacta atagaacaga taaaacagca gttgactttt
    12241 tcttgatcaa tttaaataat tcttgtttta caagcaatgt catttttctt cttccccctt
    12301 tactgaatcc agaatttcca atagagaaga ttccaaatca ttcgtcagat gctggacgtc
    12361 tgtcacatgg atattttgtg cagacaatag ctggatcacg gttcctaata attcttcgtt
    12421 ttcttttaaa agcttgattt tatcaggatc ttccaaagta tatccagctt ctgtcaagat
    12481 cgttcgagca gctagatcat ttgttgtaga gataacgatg aaatcttgcg ctgtttggtt
    12541 caattcagcc attgtacatt gtttgatgat ctttccttga ttgatcagga tcagctcatc
    12601 gaccattttt tcaagctcgc tgagtaagtg actggagatc aagaaagagg tgccctgagt
    12661 agccaagtcg gtaatgattt ttcgcacatc tcttgttgct tgtggatcca aaccgttcat
    12721 cggctcatct aaaataacga tagacggatg gttcagtaag gcaagagcaa ttcccaattt
    12781 ttgtttcatt cccaacgagt aggatttcgc ttttttgtga atgtactttt ccatcttgag
    12841 ctgattcacg atagtgtcga tagcagatac atcgttggtt tcagagaata acttcagatg
    12901 atcatagcct gttaagaatg gatagatacc cgggtattcg atcaatgctc ctacttgttc
    12961 caacccttta tgactagagg gagaaatctc attttcacca atacagattg ttccatctga
    13021 gtaatggatc agtcctaaaa tagctttcat gatcgttgtt tttccagcgc cattaggacc
    13081 tactaatcca acgattttgc caggggataa gctaaaactg acatcgctga gggcttgttt
    13141 gtgaccaaag ttcttggata attcttggac cgaaagactt ttcaaaaata ttcactcctt
    13201 ttctatagat agtacaagca tacacctgat gagtggagaa gtcgctaggt cattggactt
    13261 atttcttatt ttttcataaa aaaattgaat attaaataaa aaggcttatt ttttctgatc
    13321 agtacttatt ccaagtgtct agtggccgct agtaatcttg atgccaatga tactgatgag
    13381 tagcatcccc acaaagaacc aagtggaaag attcagctta tcatgaaaca agaccacacc
    13441 aattatgacc gaaccaactg cgccaatccc tgtccagata ggataagaga gactcatcgg
    13501 caaacttttg attgcctttg acaaaaagta aaaactagca atcatgccaa tcactgtgta
    13561 aaaagaataa ttgattttag aaaaaccatc actccatttc atcatcgttg accagaatac
    13621 ttccaaaatt cctgctatga ttaattccat ccatgccata cttacattcc tccttaacta
    13681 taaaaaaata cacaaaaaga ggaaaatcat cccttcaaag acctaatgga atgatcatcc
    13741 tctttatcct acccggtggc agattgtata tctttttctg tagtatagca cacctatcca
    13801 gatatcggca atctcatact ttttagtaaa gtgtaccaag cactgacgga tatatcgtta
    13861 gcggaaaaga agatgaatgc tttgcaattt catagaaaga agttgttatt tattaatcat
    13921 ttaaaaaaaa cagtaactag accttatttc tatatattat cgggcaataa attaaaaaaa
    13981 gctttacctt acaataagta agataatttt tgtgataaaa aaataacgaa aaatatttaa
    14041 aaatagtgtc tatttcgtga gaaaacaact atatttttta tgtgttttgc tttataatta
    14101 aaaaaatatt gtcattttat ggaggaaaat atatggaaaa ttatcttagc cttttaggcg
    14161 tcttgattgt tattctcggg tttgcattta aattagactc gatattgatc gtaatggttg
    14221 ctttagttgt tacagctttg actggcggtc ttggcattca aggaatgtta gaacttttag
    14281 gtacaagttt tgtaaacaat cgcgggatgg cgatttttat catcattatg ttggcaacag
    14341 gaacgcttga aagaaatggt ctgaaagaat cagcggcttc cttgatcaag cgattcaaga
    14401 aagtatctgc tggtatgatt gtagatattt atgggatctt tcgaatgatc tttgcggctt
    14461 ttaacgtgag ttttggtgga gttgctggat ttgttcgtcc aatcatttta ccgatggcat
    14521 tggggaccat cgaatcaaaa gggttagaag tccatcctaa gcatgaagaa gaactaaaag
    14581 gtatggcttc agctatggaa aatgtctgct ggttctttgg ccaagtacta ttcatcggag
    14641 gagcaggggc gttgctagtc caatcaacac tgaaagatct aggatatgac gtaacattgg
    14701 gacagcttgc tttagtggaa gttccagtgg ctatcacggc tttagttgtg gcaagtgtct
    14761 acttctatct taaagaaaag aaattagcga agaaatatta tccaggaaag gggcaataag
    14821 atggactttt ttacaaatcc tgatatttta ttaggcgata aattactgga gatcctttat
    14881 atcgtgatgg gactcgtatt gatttacact ggagtaagaa atttaacaga taaaaccaat
    14941 cctcatcgtt atgggtcagc ctttttctgg acggtcttag gggtagttat tgcaggagga
    15001 agatggcttc cggcaatcgt gaacggtggc ttgatctttg cgatgaccat accagcaatt
    15061 gctaagaaag tcagcaaagg agaaagccgg cttccatcaa aagaatatat ggaaaaaatg
    15121 tcagacaaac taggaatgaa aatttttatt ccagctttga gtatcggtgt ctttgcgatc
    15181 ttgtttgctc tatttaccaa tttaggtgct ttagtcggcg tgggcgtcgg tgtttttgca
    15241 gccatgctaa tcttgatgtt cttttctcga gataatcgac caagtacatt tttagatgat
    15301 gcagcagata tgctgggcac agtagggccg ttaagcatgt tgccaatgct tttagcttct
    15361 ctaggtgcgg tatttacaag cgctggagtt gggacagtga tttccaatgc agtaggtacg
    15421 atcgttccag aaggaaatgt gaacatcggc atcatcattt acgctcttgg catggtgata
    15481 tttacggtaa tcatggggaa tgcatttgcg gccatcaccg tgatgacggt tgggatcggt
    15541 gcaccattcg tatttagtca tggagcgaat ccagcgttaa taggaatggt tgcattgact
    15601 tgcggttttt gtgggaccct gctgacaccg atggctgcta acttcaatat cgtgcctgta
    15661 gcgatgctgg agatgaaaga caaatacgga gtgatcaaaa accagttgtt tattgcgtta
    15721 tttatgctag ttttccaaat tgcttatatg attctattta aataatagaa gagaggggtt
    15781 gtgacagaat aattgtcgca acctcttcta acattgtagt ggaacactat ttttttataa
    15841 gaatatatta agtttgatct gttatgttat ttaaactatt gtttccttta tttacgctgt
    15901 tcaaggaaaa tggtatgata aaagataacc atatgttaaa tcaatcggac ggaggaacaa
    15961 cagatgaaag tactagtaac aggttttgat ccatttggtg gggacaaagt gaatccagcc
    16021 tatgaagcag taaaaaaaat gccagatgaa atcagcggtg ctgaaatcat caaagtggaa
    16081 gtaccgaccg tattcgaaaa aagcagtcaa gtagtcaaag aagccatcca acagcaccaa
    16141 ccagatgtcg tgatctgtgt cggacaagca ggtgggcggt cagcagtctc gttcgaacgt
    16201 gtcgcaatca atctagcaga agcaagaatc cctgataatg aaggaaatca gccattcgat
    16261 acggctttag aagaaaacgg tccagccgct tactttacct cattgccaat caaagcaatg
    16321 acaaaaaatg tacaagatca tggtctacca gcgtacatct cttatacagc aggaacattt
    16381 gtctgcaatg atatcatgta tcgtttgctt catttgatcg aaacacaatt cccggcaatt
    16441 cgaggtgggt tcatccacgt gccattctca cccgatcaag tgatcgatcg tccagtgggt
    16501 acgccttcta tgtctttaga agacattgct tcttctttga cttatgcagt tgaagcagca
    16561 gtagaaaata aagaagatat ttccggaaat gccggaacaa ctcactaatt tagcaagaaa
    16621 cactggctgg ttgctaacgt tatgttagta gccagctttt tgtaattaga aaggaaagaa
    16681 acagccgtgg aagaatggca atccgtcttt gaagaatggt ttccaaaaga aatcagcaaa
    16741 agctatccca tcaaaatttc taaacaatac acaagcagtc aacgttggga gatctatgca
    16801 aaattaacga aaaaacagcg ggaactagtc gataagcacc gccgatatct aatcagctct
    16861 cgttttatgg aagaacatta tttagctgca acagattggg tgttttctga cttcaagatc
    16921 aatccgtttt ttcgaacaaa acgaagccag caaaaattgt attgtgagtg tggtagagaa
    16981 ttaaaagtgc aatacatcgt taaatcgcca aaaaccggaa agatcctaaa actaggcatc
    17041 aaccactttg ccgatcacct gcatgtctct ccgacagtgg cagcttcgat ccatcaggga
    17101 atgacaaaag ttgatctggc cttagacgaa ttattatggc ttaagcagaa gaatatcgat
    17161 tttcctgaag gactatggca aaaatactgt tttgtcttgt accaaaatcg tcggatgaaa
    17221 cagccatatt taccggatat aaaattagct cagcggctcg cagaatttcg ccaagtagaa
    17281 atgccgattt acatagcgga ttatcaagca ttggaaaatg aaatcaagaa aataagtgaa
    17341 cacatcaatg ggcagtcaaa aaagcgacag ataaaaaaag aactatttga cgactttgca
    17401 gaagaattag taaaggatgt agaagaattc ttgatcaact atcgcgcatt tttacgtaaa
    17461 gattggcaat ccatcgtata tgaagaagtg ccagtacatc ctaatgctta ttttgaaaca
    17521 tttatttccg tgttgagaaa gacaaaacgt caacgaacac cagaagtcac tgctcagatg
    17581 gaatattttg cgaaaaacca acgattcatc caaccaaaaa tctatctatt tatttggaag
    17641 caatattgtc gctatggttt tacagaaggg ttcttcgaca gcattcctcg gatagtcaga
    17701 aatggttttt taaaagtatt gcgtaaagaa cgagaagcta tacaatctgc tgataagaaa
    17761 gaccgtacag tctcaaaaga aaaatggcaa ctagtagtga aagatatcca atctggaaat
    17821 gtgcaagaga caatcgacaa atggaaagga aaacattatc gttttactga agctcagaaa
    17881 caagcgttgg aatattatca gaagttagaa gaatcactgc gtttcaatga tgaggcaaga
    17941 aagtatctga aggaattact ataaaaaata gaggctggga cagaagcgtt taactccaag
    18001 aaataagaa
//
LOCUS       DAFEEZ010000196         8774 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.guided.093, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000196
VERSION     DAFEEZ010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8774
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.guided.093"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(565..792)
                     /locus_tag="LP245_003053"
     CDS             complement(565..792)
                     /locus_tag="LP245_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1520880.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            complement(801..1274)
                     /locus_tag="LP245_003054"
     CDS             complement(801..1274)
                     /locus_tag="LP245_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBL1520881.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            complement(1914..2087)
                     /locus_tag="LP245_003055"
     CDS             complement(1914..2087)
                     /locus_tag="LP245_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL1520882.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            2504..3070
                     /gene="amaP"
                     /locus_tag="LP245_003056"
     CDS             2504..3070
                     /gene="amaP"
                     /locus_tag="LP245_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBL1520883.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            3083..3271
                     /locus_tag="LP245_003057"
     CDS             3083..3271
                     /locus_tag="LP245_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBL1520884.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            3284..3841
                     /locus_tag="LP245_003058"
     CDS             3284..3841
                     /locus_tag="LP245_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL1520885.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            3873..4115
                     /locus_tag="LP245_003059"
     CDS             3873..4115
                     /locus_tag="LP245_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL1520886.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            4456..5670
                     /locus_tag="LP245_003060"
     CDS             4456..5670
                     /locus_tag="LP245_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBL1520887.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            5701..5919
                     /locus_tag="LP245_003061"
                     /pseudo
     CDS             5701..5919
                     /locus_tag="LP245_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6338..6811
                     /gene="dfrF"
                     /locus_tag="LP245_003062"
     CDS             6338..6811
                     /gene="dfrF"
                     /locus_tag="LP245_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBL1520888.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            6938..7594
                     /locus_tag="LP245_003063"
     CDS             6938..7594
                     /locus_tag="LP245_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBL1520889.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            7776..8306
                     /locus_tag="LP245_003064"
     CDS             7776..8306
                     /locus_tag="LP245_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL1520890.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
BASE COUNT         3064 a         1305 c         1731 g         2674 t
ORIGIN      
        1 ctcgagttac gagtttggaa cagcttttgt ctacagtctg tcattattat caaaataatg
       61 ttaaaaataa aaaagaattg tccatcactg ttattcaaat cattttatca aaactacata
      121 gtaaatgtta aaaagcaaca tgacataata tatagaaggc tttacagtat atatgggagc
      181 ttactaaaaa agaatggagt aagagttaac acaatgggcc attagctgaa gttttaagca
      241 cttcaaggta tgaaacagaa tggcctgtaa tactacatga ttatttagac tgctcaaact
      301 gctatcagtc tggtggaatg aataaagtat tatactaaaa gcagatccaa ctacaacgta
      361 acaggaaacc agttgtatca ggaaaagtga tagtacatgg agaagaaaag gccccctttg
      421 tatgagtcag tacatatctt atttatagat aaaacggtat tcaatcgaaa taaaaaatct
      481 gaataataga cgtaaataac ttctaaaagt ctcacacatc tatcattcag attatttttt
      541 atttactgtt tgttctactt tattttattc ttctggtata gtattcgagt catttttata
      601 ggtcaacaaa tcacctggtt gacactccaa aacttggcag attttttcga gagtggaaaa
      661 acggatggct tttgcttttc cattttttag aatagagatg tttgccatcg taatgcccac
      721 tttctcactc aattcagtca cactcatttt tttttgagct aatactacat ctaaattaac
      781 gataattgcc atgtcgcacc tcacactgtc aaatcatgat ctgtcttaag taaaatcgca
      841 tgttcaagca gtttttccag cacgcttgtt aatgtgtata ctgcaaaagg aatgaatacg
      901 acagcgattc ctaccaacat caaacctgga gcatcgtcta aatccgctac tttcataaat
      961 ttaggaagta agccaaaaaa ggcgaaacca ataaacaaaa tggttcgttc gatttttttt
     1021 agtatgttta agctttgagt ggaaaaagct tggttatctt cgattttttt caatagtttc
     1081 aataagaaat aagcaataac gatccctagg agaagggcaa agtaaatgac agaaacaaat
     1141 aatgtggtct gccaatcaaa attgaatcct ttttcgcttg tagcgatctg agtataaaaa
     1201 agtacgccga acaaaataaa tacggcactt atacctaaaa cgacaaattt taatagcaat
     1261 gttttaaatt tcatttttat ccctctttta tctttgatag ctaaaatata gcagaataat
     1321 tattgtaaaa caactatttt ttatcgaaaa acaataaaaa tatatcgttt ataaaaaatg
     1381 atagagtatg aaggtgtgga gtgcatttaa cagctttttt tgattgtaag aaacatttaa
     1441 aaccagttat tttagattct atgtgtgtct cttctataat gctagtttag atgcctggga
     1501 ttatattgga caatacagtt ggaggatttt ttattatcta gcgaagagaa gtgtaagtta
     1561 acagaactgt atgagaaaaa agacaactac gtagtagcta accgattcat taattttttc
     1621 aagttcatgt ttatttacgt atcagaattt ttcttattca atggtttggt gtaatcacca
     1681 cttatttgtc ctttattgct tatacaatgt tatacaaaag gaaaatcaag cattgacgca
     1741 tggggtggta ctatctagct gaaatagctt aataagcgca agtagatgca ttggattagt
     1801 ttataaatca aaagtgttag aggtattaag aagaagtaga aaaataaaat ggattgccga
     1861 ataaaaagta ccataaatcc taaaacatgt gccaacagat agatggcaca tgtttatttt
     1921 tttcgataat tttgtaacaa aaatacgaag atgaaaaaga atagagattc ccataatgta
     1981 gtagtccaac tgaattcttt actgatacca aataccatat ttcctagatt tgatacaatc
     2041 aaatagccaa tcgttatgat caatgaatag tacaatcttt tcatcatagg acatacctcg
     2101 tttttattta taagaatagt ataaaccaaa gaagtgaata agaaaaatga taatataaaa
     2161 ataaagtaag aacgcattaa agtaactaaa gttatttatt gtatttttta attctccgaa
     2221 aaaatttaat aaataaatag aatcttgtaa taataactga gcataatctt tgcaattttt
     2281 aatcttgaat aatatccttt aagtatagcc agcaatcaaa agtaaataga gaataagtaa
     2341 gcaattgtta tttcagtatc agactggcaa taaaacgccg ttatgatcca gcaatgtttg
     2401 gtagcgcttt atttactgat gctatgctaa ctgttcgcta tctatactgt gattgtcggt
     2461 agagttattt acagggtaaa aataagttta taggaggtgg aaaatgaata aggggttaaa
     2521 aataatcggt gttatcatga gtttactgct actttcagta tttctagcga ttgcgttgat
     2581 caatgcgccg tatattatgc ctgaacaatt ggaacgattt cgcttcttta ctttaacgaa
     2641 ttactacatg caacaatata ttttctgggc agctgtagta tttgccgttc ttgctattat
     2701 catcttgcta gtcgttcttt tctatccaaa gtcaagagga actttcgtta tgaaacggga
     2761 agatggcaaa ctaacaatcg acaaaaaagc gatcgaaggg ttggtacgtt cccatttaca
     2821 cgaagaagag ttcattcatt cacctaaagt acggatacgt tcaacgaaaa atcgaatcca
     2881 tatccatgtc aacggagact tgaaacgaac ttcttcatta gtagggaaaa caggtgtatt
     2941 gatgcaagat atcgaagaag aagtaactaa agtactcgga acaaaagaaa cggtcaaagt
     3001 ggcagtcaca tacagcggtt atgaagaaca agaagataca agagactaca agcactctcg
     3061 agtggaatag gagggccaaa taatgaaaga actattttca gcatacaagc tccctattat
     3121 ctttgggggt cttggactac tgctagctgt tttatggtta acgattggat ttttcaagac
     3181 attgttgatc ataatcatga cagcaattgg cgcaggaatc ggtttttatt tgaaacagtc
     3241 aggaatagtt gatcaatttt ttaaatcata ggaggaaaca aagatggaaa acaaaaacat
     3301 gaatacaaca aatggatcag ttttggcaaa tgaaaaagga gaaaaccgca tgatgaatgg
     3361 tgaattgact tatgaagaca aagtcatcca aaaaatcatc ggttatgcat tgaaagatgt
     3421 agatggtcta ttgacattag atggcggatt tttctcaaat atggctgaaa aattagtcaa
     3481 cacagataac gtaacagcag gtatcaatac agaagtaggt aagaaacaag tagctgtgga
     3541 tctagatgtg atcgtagaat acggtaaaga catcgaagat atttacaacc aaatcaaaga
     3601 attgatcagt actgaagtaa acaatatgac acatttagat gttatcgaag tgaatgtgaa
     3661 tgttgcagac atcaaaacac aagaagaata ccaaaaagat caagaaacag tacaagacaa
     3721 agtaacagaa gcagcaaaat ccacaggaca atttgcttca cgccaaacag ataaagcaaa
     3781 atctgctgta ggcaaaggtg cacaaaaagt caaagaaaat aacgaaccac gtgtacaata
     3841 agaagtaaga agtcagttag gaggaattta aaatgggatt tatttgggca ttaatcgtcg
     3901 gcggtatcat tggagcaatt gcaggagcaa tcacgaataa aggatcatca atggggatca
     3961 tcgcaaacat cattgctggt ttagtaggtt cagcaattgg acaagcttta ctaggaactt
     4021 ggggaccaac aattgcagga atggctatca ttccatcatt gatcggtgca atcattttag
     4081 tattagtcgt ttcattcttt gcacgtaaat tataagcaaa ttgaagaaaa acttatgttg
     4141 aaatgaagaa caaatttgag aaccgtagcg acactcgctg cggttctttt ttatatattt
     4201 tatatgaagt attctttatt ccttatgaaa aaatatcttt aaaaataaaa aaagacgaaa
     4261 ataaacggtt ttctataaaa agaagaccgt ttattttttg tctttatttg tgtgaaaaac
     4321 gaaaaagagc acaacacatc aagcttttat taattgtctg tcttttataa atgcaagtat
     4381 taattcaaaa aaacagaaga aaaaaacaac tacaccttct tttatactcg taatcgtaga
     4441 aaggaggcga aaaaaatgaa tacattacct atcaatacag gagatacagc attcatgatt
     4501 ttatgtacag caatggtttg cctgatgact cctggtctag ctttttttta cggcggatta
     4561 gcacggaaga ataatatact aacgatcatg tctcaatctt ttctctccgt tgggataaca
     4621 acgattatgt gggtatttgg tggattcgga ttggcctttg gacgggatat cggcggtgtt
     4681 attggaaacc cggcagattt ctttttgatg agacatgtta caagcttccc caacatgttt
     4741 catggtgcaa cgattccatt tttaatgttc tttctttacc aactgatgtt tatcgtgatt
     4801 accgttcctt tgatgacagg agcttttgca gggagattga atttaaaagg ctatattata
     4861 cttgttattt tttggaatct gctgatttat ttccctgttt gccactggat atggggtggc
     4921 ggatttttgg atcagatggg atttagagat ttcgctggtg gagcagtcat ccacacgaca
     4981 gctggattcg gctctttagc atgtatcctc acacttggtc aaagaaagat tcctttagga
     5041 gaaagaagtc agcatagcag tcttatggca gctgctatcg gtacaggact gctttggttt
     5101 ggctggttcg gttttaattc cggtggtgca cttcgagcag atgaacaagc agtcaatgca
     5161 tttggttcaa cattcatcgc tcttgcattt gcgatgatta cttggctgat cattgcaaaa
     5221 gtaaaaggaa atggctttga ttttgtcgac gtactaacag gatccgttgc tggattggca
     5281 gccattacgc cttgtgccgg ttatgtagaa gcaaaaagtg ccatgctgat tgggatcatt
     5341 gcgggtatcg tctgtcatgc tgctgttgat tttcgtaaaa agaaacaatg ggatgatgca
     5401 cttgatgtgt ggggtgttca tggcatgggc ggattcacag gtacgattct gatagggatc
     5461 tttgcatcta acagccattt actaacgaat ccaagcagct ggtacttctt agggattcaa
     5521 gtgattggtg tcatcattac tgccgtgtat gcctatgtgc tgacaacagt gattttaaaa
     5581 tcggcgatgc actttacaac gatcactact acaaaagaag aacaagaaga aggattggac
     5641 tttttcttct ttggcaacaa actcaattga aacaaattca aatagaaaag aggaagattc
     5701 atgcaacaaa gcaaaacgaa aattcctgca aaaaaattaa cgttctttgg ctttttggct
     5761 atgaccatct caatggtcgt ttcattatat gaatatccca cattcgcgac ctcaggcttc
     5821 agcttagtat ttttcttgtt attaggcggt ttgctatggt ttatccctgt ggcattgtgc
     5881 gcagcagaga tggcaacggt gaaaggatgg gaaaaaggtg tttcccaaac aaaaagatat
     5941 taagaaacag cccatgttta cctgcttgca aacaaaagaa tattgctact agactaagag
     6001 atactacata agtgtgttgg tatctctttt ttgttgccgt gaaacagcag actatttcat
     6061 ttctgcttga ttaccttaaa acttattagt ctatggtttg tcaagggctt gttgcgtgag
     6121 aaatgctgaa tatcaccctt tacaaaacat aggctgataa gtaacttttc aaaagcagaa
     6181 aagaaatggc aatgcttata acaatatgat ataatgcaga tgaagacaaa aaaggaattt
     6241 gtcgagctgg ttagttcgag ataattttga gtttgttaag atgtggtgca cttgatggaa
     6301 tcacaggtac gacatcatat tatggaggat gaaatagatg ataggtttga ttgttgcgag
     6361 gtcaaagaat aatgttatag gcaagaatgg taatatacca tggaaaataa agggagaaca
     6421 aaagcaattt agagagttaa caacgggtaa tgtggttatt atggggcgaa agtcttatga
     6481 agaaatcggt catccgttgc ctaatagaat gaatattgtt gtttccacca caacagagta
     6541 tcaaggagat aatttagttt cagttaaatc attagaagat gcattattat tggctaaagg
     6601 acgagatgta tacatatctg gtggatatgg actatttaag gaagctttgc aaatagtaga
     6661 taaaatgtat atcacagaag tagatttaaa tattgaagat ggagatacat tctttccaga
     6721 atttgatatc aatgattttg aagttttgat aggggaaaca cttggtgagg aagtgaaata
     6781 tacgagaaca ttttatgtaa ggaaaaaatg aattgagtaa attttggatt tagggtgttt
     6841 tcataaatat attgcttttt atgcatatat aaattgttgt aagacaaatt ccagtttgta
     6901 tggggcgata aaatcagaat ttgagagagg attgaatatg aataaggaat ggtctgaact
     6961 taataaaaca atgcaggcac aaataaaaaa gaaagatact tataagaggg gtattgatac
     7021 tttacttact ttacgaagtc agttaataca aaccttagta tctttcaaag aagaattatg
     7081 cagagaagat tttaactcaa tccccttcat aaacgctgat ggttatcata gtaagacgat
     7141 tgcttattct atttggcata ttttccgcat tgaagatata gttgtgcata cagtgataaa
     7201 tgaagatgaa caagtatttt ttgcaggcaa ttatcaagag cgtatcaatt cacctatcat
     7261 tacaacagga aatgaactca tgaaacagca gattgcagac ttttcaaaac agcttaatct
     7321 ggaagaatta tatttatata ttttcgaagt atgggaaagc actgagaaaa tgcttgaacg
     7381 gttatcttat gatgaattga aaagaaaaat accgaaagaa agaaaaggat acttagaatc
     7441 gttgaatgta gtaaacgaca atgaaaaagc aatttggctg attgattatt ggtgtaataa
     7501 agatatttgt ggactaattc aaatgccgtt ttcaagacat tggattatgc acacagaagc
     7561 ctgtttgcgt ataaagaaca agatacattc ataggcaaaa atttcagttt gtagaactaa
     7621 ggaaattgga atttaaggag gaataaagta tggttagtga ttttataaga gcagcatttc
     7681 catggatttt aatgggttta tttgtagcaa tcagttgttc ccttatgagt aaaaaagaga
     7741 aataaattcc tgtttgtatt tataaaagag aaaaaatgag aaaagtagtt ttatttattg
     7801 ccatgagcct tgacggatat attgcggacg gtaatggtgg agtagcttgg ctaaatggtc
     7861 atggaaatga caatgaaaac atcgacactt atacagaatt taccaaagat atagatactg
     7921 tcttaatggg gtggaatact tctcatcagg ttgttactga actttctccg caagaatggg
     7981 tatataataa atttacaact tatgtattaa cacataaaga gtgcaattct tcccaacaaa
     8041 ttcattttac aagtgaaaat cctgttttat tattggaacg gctaaaacaa gaagcaggaa
     8101 aggatatttg gatttgtggc ggagcaaatc ttgttcagca gttggtaagc aaaaatatga
     8161 ttgataaata ttacatttct gttattccta ctctgttagg aaatggggtt cgtcttttgg
     8221 gcaacataga cagggaaata aagttaaggc tttgtaaaac acagacttat aacggaataa
     8281 ccgatttgat ttatatgcgt agataactag agagaaacag aaaagctgtt aaaccgacgg
     8341 agcgatccga ccacgttggc gggaaaatcc ttaagatttt tccgccatgc ttgcaagggg
     8401 gcggttcgct tcggcggttc ggcgagcttg cgagccgttc aaagcccccg ttatctaaca
     8461 aggggggcac aaaaaacaag aaacactata cactaacaag cggaaaacgc tgtatttata
     8521 aggcaaaacc ccatttttac agtagtgata taaattgtac ctatatcact atgaaaattg
     8581 aatagtaaat atgagaaaga cagttgattt caaaaaataa gaaattgatt gtcgttttct
     8641 tttgcagaaa tttaagtgca ggcaattatg gtagttgtcg taattgctgt cagctcagtg
     8701 tttatcactg atggtgtgaa agatttacgg ttggagagta agcgccccat agaacagtac
     8761 cttactaaca aatg
//
LOCUS       DAFEEZ010000197         8062 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.guided.101, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000197
VERSION     DAFEEZ010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.guided.101"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            128..1564
                     /locus_tag="LP245_003065"
     CDS             128..1564
                     /locus_tag="LP245_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL1520891.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="LP245_003066"
     CDS             1753..4200
                     /locus_tag="LP245_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBL1520892.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="LP245_003067"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="LP245_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL1520893.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="LP245_003068"
     CDS             complement(5690..6793)
                     /locus_tag="LP245_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL1520894.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="LP245_003069"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="LP245_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBL1520895.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2697 a         1375 c         1751 g         2239 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattacttc ttgaattttt gtgaaattcc
     7981 aacttatttc cgaagaagct acttttggaa caccgtgtac cagaggttgt gaaaaagtcg
     8041 cttagtttcg agtagtaaga aa
//
LOCUS       DAFEEZ010000198         6376 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.guided.108, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000198
VERSION     DAFEEZ010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.guided.108"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="LP245_003070"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="LP245_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBL1520896.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="LP245_003071"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="LP245_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HBL1520897.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            3976..5238
                     /locus_tag="LP245_003072"
     CDS             3976..5238
                     /locus_tag="LP245_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBL1520898.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            5483..6370
                     /locus_tag="LP245_003073"
     CDS             5483..6370
                     /locus_tag="LP245_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001611915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HBL1520899.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHKKWFCCKVLNKE"
BASE COUNT         2210 a          906 c         1313 g         1947 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcgggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaggaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc
     3841 ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata gtgtgttata
     3901 ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg ccacctaaaa
     3961 aggagcgatt tacatatgag ttatgcagtt tgtagaatgc aaaaagtgaa atcagctgga
     4021 ctaaaaggca tgcaatttca taatcaaaga gagcgaaaaa gtagaacgaa tgatgatatt
     4081 gaccatgagc gaacacgtga aaattatgat ttgaaaaatg ataaaaatat tgattacaac
     4141 gaacgtgtca aagaaattat tgaatcacaa aaaacaggta caagaaaaac gaggaaagat
     4201 gctgttcttg taaatgagtt gctagtaaca tctgaccgag atttttttga gcaactggat
     4261 ccaggagaac aaaaacgatt ttttgaggaa agttataaat tattttccga acgatatggc
     4321 aagcaaaata ttgcttatgc aacagttcat aatgatgagc aaacccctca catgcattta
     4381 ggtgttgtgc ctatgcgtga tggaaaactg caaggaaaaa atgtgtttaa tcgtcaagaa
     4441 ctgttatggc tacaagataa attccccgag catatgaaaa aacagggttt tgagttgaag
     4501 cgtggtgaac gtggctctga ccgtaaacat attgagacag ctaaatttaa aaaacaaact
     4561 ttggaaaaag agattgattt tctagaaaaa aatttagcag ttaaaaaaga tgaatggact
     4621 gcttatagcg ataaagttaa atcagattta gaagtaccag cgaaacgaca catgaaaagt
     4681 gttgaagtgc caacgggtga aaagtccatg tttggtttgg gaaaagaaat aatgaaaaca
     4741 gaaaagaaac caaccaaaaa tgttgttata tcggagcgtg attataaaaa cttagtgact
     4801 gctgcgagag ataacgatag gttaaaacag catgttagaa atctcatgag tactgatatg
     4861 gcgagagaat ataaaaaatt aagtaaagaa catgggcaag ttaaagaaaa atatagtggt
     4921 cttgtagagc gatttaatga aaatgtaaat gattataatg agttgcttga agaaaacaag
     4981 tctttaaagt ctaaaataag cgatttaaag cgtgatgtga gtttaatcta tgaaagcact
     5041 aaggaattcc ttaaggaacg tacagacggc ttaaaagcct ttaaaaacgt ttttaagggg
     5101 tttgtagaca aggtaaagga taaaacagca caattccaag aaaaacacga tttagaacct
     5161 aaaaagaacg aatttgaact aactcataac cgagaggtaa aaaaagaacg aagtcgagat
     5221 cagggaatga gtttataaaa taaaaaaagc acctgaaaag gtgtcttttt ttgatggttt
     5281 tgaacttgtt ctttcttatc ttgatatata tagaaataac gtcattttta ttttagttgc
     5341 tgaaaggtgc gttgaagtgt tggtatgtat gtgttttaaa gtattgaaaa cccttaaaat
     5401 tggttgcaca gaaaaacccc atctgttaaa gttataagtg accaaacaaa taactaaata
     5461 gatgggggtt tcttttaata ttatgtgtcc taatagtagc atttattcag atgaaaaatc
     5521 aagggtttta gtggacaaga caaaaagtgg aaaagtgaga ccatggagag aaaagaaaat
     5581 cgctaatgtt gattactttg aacttctgca tattcttgaa tttaaaaagg ctgaaagagt
     5641 aaaagattgt gctgaaatat tagagtataa acaaaatcgt gaaacaggcg aaagaaagtt
     5701 gtatcgagtg tggttttgta aatccaggct ttgtccaatg tgcaactgga ggagagcaat
     5761 gaaacatggc attcagtcac aaaaggttgt tgctgaagtt attaaacaaa agccaacagt
     5821 tcgttggttg tttctcacat taacagttaa aaatgtttat gatggcgaag aattaaataa
     5881 gagtttgtca gatatggctc aaagatttcg ccgaatgatg caatataaaa aaattaataa
     5941 aaatcttgtt ggttttatgc gtgcaacgga agtgacaata aataataaag ataattctta
     6001 taatcagcac atgcatgtat tggtatgtgt ggaaccaact tattttaaga atacagaaaa
     6061 ctacgtgaat caaaaacaat ggattcaatt ttggaaaaag gcaatgaaat tagactatga
     6121 tccaaatgta aaagttcaaa tgattcgacc gaaaaataaa tataaatcgg atatacaatc
     6181 ggcaattgac gaaactgcaa aatatcctgt aaaggatacg gattttatga ccgatgatga
     6241 agaaaagaat ttgaaacgtt tgtctgattt ggaggaaggt ttacaccgta aaaggttaat
     6301 ctcctatggt ggtttgttaa aagaaataca taaaaaatgg ttctgttgca aagttttaaa
     6361 taaagaataa aatccc
//
LOCUS       DAFEEZ010000199         4995 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.guided.125, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000199
VERSION     DAFEEZ010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.guided.125"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            complement(30..2180)
                     /locus_tag="LP245_003074"
                     /pseudo
     CDS             complement(30..2180)
                     /locus_tag="LP245_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            2326..2901
                     /locus_tag="LP245_003075"
     CDS             2326..2901
                     /locus_tag="LP245_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1520900.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            3115..3810
                     /gene="vanR"
                     /locus_tag="LP245_003076"
     CDS             3115..3810
                     /gene="vanR"
                     /locus_tag="LP245_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBL1520901.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            3788..4942
                     /locus_tag="LP245_003077"
     CDS             3788..4942
                     /locus_tag="LP245_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBL1520902.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT         1560 a          939 c          967 g         1529 t
ORIGIN      
        1 aattttcttc tttcagcttt ttatttccca cttgtaaatc ggtagatggt ggctcctttt
       61 ccagttccat aatgtggatt tgcatctgca tgtagtgatg aaacacctag ctgcattctc
      121 ataccatctg acgaagatgt tgtaccgtcg ccccaataga aaggcaattg taatttatga
      181 tgaaagttta ctaatatggc ttgggcttta ttcatggcat cttcatacat gcgccattga
      241 gatacattgg ctagttgctt atatgtaagt ccgggtgtgg cttcggccat cttgctcaag
      301 ccaatattca ttcccattcc taaaagggca gccatgataa tgattgtttc ttccttatct
      361 ggttttcgat tattggaagc atgagtgaat tgctcatgaa atcctgttat atgggccaca
      421 tccatgagta aatcagttaa ttttattctt ggtagcatct gataaaggct tgcactaaat
      481 ttttttgctt cttctggaac atctttttct aagcgtgcaa gtgatagctt tcctttttca
      541 agagaaaccc catctaactt attggaattg gcagctaacc actttaacct ttcattaaag
      601 ctgctggttc tctccgttat ataatcttcg aatgataaac taactgataa tctcgtattc
      661 cccttcgatt gattccatgt atcttccgaa aacaaatatt cctcaaaatc cctatattgt
      721 ctgctgccaa caatggaaac atctcctgcc cgaacatgct cccgaagttc tgttaaaaca
      781 gccatttcat agtaatgacg attaattgtt gtaccatcat cctcgtataa atgtcttttc
      841 catcgttttg aaataaaatc cacaggtgag tcatcaggca cttttcgctt tccagattcg
      901 ttcattcctc ggataatctc aacagcttgt aaaagtggct catttgcctt tgtagaatga
      961 aattccaata ctcttaatag cgttggcgta tattttctta gtgaataaaa ccgtttttgc
     1021 agtaagtcta aataatcata gtcggcagga cgtgcaagtt cctgagcctc ttctactgaa
     1081 gagacaaagg tattccattc aataaccgat tctaaaacct taaaaacgtc taatttttcc
     1141 tctcttgctt taattaatgc ttgtccgatg ttcgtaaagt gtataacttt ctcatttagc
     1201 tttttaccgt tttgtttctg gatttcctct tgagccttac gaccttttga taacaaacta
     1261 agtatttgcc tatcatgaat ttcaaacgct ttatccgtta gctcctgagt aagttgtaat
     1321 aaatagatgg ttaatatcga ataacgttta ttttcttgaa agtcacggaa tgcatacggc
     1381 tcgtatcttg agcctaagcg agacagctgc aacaggcggt tacggtgcaa atgactaatt
     1441 tgcactgttt ctaaatccat tcctcgtatg tattcgagtc gttctattat ttttagaaaa
     1501 gtttcgggtg aaggatgacc cggtggctct tttaaccaac ccaatatcgt tttattggat
     1561 tcggatggat gctgcgaggt aataatccct tcaagctttt ctttttgctc atttgttaga
     1621 gatttactaa ccgtattaaa tagcttcttt tcagccattg cccttgcttc ccacaccatt
     1681 ctttcaagtg tagtgatagc aggcagtata attttgtttt ttcttagaaa atctatgcat
     1741 tcatgcagta gatgaatggc atcaccattt tccaaagcta attgatgaag gtacttaaat
     1801 gtcattcgat attcactcag ggtaaaagtt acaaagtcgt attcacttcg aatttctttc
     1861 aaatgatccc aaagtgtatt ttccctttga ggataatgat caagcgagga tggactaaca
     1921 ccaatctgtt tcgatatata ttgtatgacc gaatctggga tgcttttgat atgagtgtat
     1981 ggccaaccgg gataccgaag aacagctaat tgaacagcaa atcctaaacg gttttcttcc
     2041 ctccttcgct tattaactat ttctaaatcc cgtttggaaa aagtgaagta ggtccccagt
     2101 atccattcat cttcagggat ttgcataaaa gcctgtctct gttccggtgt aagcaattct
     2161 ctacctctcg caattttcat tcagtatcat tccatttctg tattttcaat ttattagttc
     2221 aattatatat caatagagtg tactctattg atacaaatgt agtagactga taaaatcata
     2281 gttaagagcg tctcataaga cttgtctcaa aaatgaggtg atattttgcg gaaaatcggt
     2341 tatattcgtg tcagttcgac taaccagaat ccttcaagac aatttcagca gttgaacgag
     2401 atcggaatgg atattatata tgaagagaaa gtttcaggag caacaaagga tcgcgagcaa
     2461 cttcaaaaag tgttagacga tttacaggaa gatgacatca tttatgttac agacttaact
     2521 cgaatcactc gtagtacaca agatctattt gaattaatcg ataacatacg agataaaaag
     2581 gcaagtttaa aatcactaaa agatacatgg cttgatttat cagaagataa tccatacagc
     2641 caattcttaa ttactgtaat ggctggtgtt aaccaattag agcgagatct tattcggatg
     2701 agacaacgtg aagggattga attggctaag aaagaaggaa agtttaaagg tcgattaaag
     2761 aagtatcata aaaatcacgc aggaatgaat tatgcggtaa agctatataa agaaggaaat
     2821 atgactgtaa atcaaatttg tgaaattact aatgtatcta gggcttcatt atacaggaaa
     2881 ttatcagaag tgaataatta gccattctgt attccgctaa tgggcaatat ttttaaagaa
     2941 gaaaaggaaa ctataaaata ttaacagcct cctagcgatg ccgaaaagcc ctttgataaa
     3001 aaaagaatca tcatcttaag aaattcttag tcatttatta tgtaaatgct tataaattcg
     3061 gccctataat ctgataaatt attaagggca aacttatgtg aaagggtgat aactatgagc
     3121 gataaaatac ttattgtgga tgatgaacat gaaattgccg atttggttga attatactta
     3181 aaaaacgaga attatacggt tttcaaatac tataccgcca aagaagcatt ggaatgtata
     3241 gacaagtctg agattgacct tgccatattg gacatcatgc ttcccggcac aagcggcctt
     3301 actatctgtc aaaaaataag ggacaagcac acctatccga ttatcatgct gaccgggaaa
     3361 gatacagagg tagataaaat tacagggtta acaatcggcg cggatgatta tataacgaag
     3421 ccctttcgcc cactggagtt aattgctcgg gtaaaggccc agttgcgccg atacaaaaaa
     3481 ttcagtggag taaaggagca gaacgaaaat gttatcgtcc actccggcct tgtcattaat
     3541 gttaacaccc atgagtgtta tctgaacgag aagcagttat cccttactcc caccgagttt
     3601 tcaatactgc gaatcctctg tgaaaacaag gggaatgtgg ttagctccga gctgctattt
     3661 catgagatat ggggcgacga atatttcagc aagagcaaca acaccatcac cgtgcatatc
     3721 cggcatttgc gcgaaaaaat gaacgacacc attgataatc cgaaatatat aaaaacggta
     3781 tggggggttg gttataaaat tgaaaaataa aaaaaacgac tattccaaac tagaacgaaa
     3841 actttacatg tatatcgttg caattgttgt ggtagcaatt gtattcgtgt tgtatattcg
     3901 ttcaatgatc cgagggaaac ttggggattg gatcttaagt attttggaaa acaaatatga
     3961 cttaaatcac ctggacgcga tgaaattata tcaatattcc atacggaaca atatagatat
     4021 ctttatttat gtggcgattg tcattagtat tcttattcta tgtcgcgtca tgctttcaaa
     4081 attcgcaaaa tactttgacg agataaatac cggcattgat gtacttattc agaacgaaga
     4141 taaacaaatt gagctttctg cggaaatgga tgttatggaa caaaagctca acacattaaa
     4201 acggactctg gaaaagcgag agcaggatgc aaagctggcc gaacaaagaa aaaatgacgt
     4261 tgttatgtac ttggcgcacg atattaaaac gccccttaca tccattatcg gttatttgag
     4321 cctgcttgac gaggctccag acatgccggt agatcaaaag gcaaagtatg tgcatatcac
     4381 gttggacaaa gcgtatcgac tcgaacagct aatcgacgag ttttttgaga ttacacggta
     4441 taacctacaa acgataacgc taacaaaaac gcacatagac ctatactata tgctggtgca
     4501 gatgaccgat gaattttatc ctcagctttc cgcacatgga aaacaggcgg ttattcacgc
     4561 ccccgaggat ctgaccgtgt ccggcgaccc tgataaactc gcgagagtct ttaacaacat
     4621 tttgaaaaac gccgctgcat acagtgagga taacagcatc attgacatta ccgcgggcct
     4681 ctccggggat gtggtgtcaa tcgaattcaa gaacactgga agcatcccaa aagataagct
     4741 agctgccata tttgaaaagt tctataggct ggacaatgct cgttcttccg atacgggtgg
     4801 cgcgggactt ggattggcga ttgcaaaaga aattattgtt cagcatggag ggcagattta
     4861 cgcggaaagc aatgataact atacgacgtt tagggtagag cttccagcga tgccagactt
     4921 ggttgataaa aggaggtcct aagagatgta tataattttg gctctttgtc aaatgatgtt
     4981 ggtaaagaga aatct
//
LOCUS       DAFEEZ010000200         4662 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.guided.129, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000200
VERSION     DAFEEZ010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.guided.129"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            366..1277
                     /locus_tag="LP245_003078"
     CDS             366..1277
                     /locus_tag="LP245_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HBL1520903.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1430..1915
                     /gene="vanZ"
                     /locus_tag="LP245_003079"
     CDS             1430..1915
                     /gene="vanZ"
                     /locus_tag="LP245_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBL1520904.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(2202..2531)
                     /locus_tag="LP245_003080"
     CDS             complement(2202..2531)
                     /locus_tag="LP245_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL1520905.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            2836..3165
                     /locus_tag="LP245_003081"
     CDS             2836..3165
                     /locus_tag="LP245_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL1520906.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            3155..3442
                     /locus_tag="LP245_003082"
     CDS             3155..3442
                     /locus_tag="LP245_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL1520907.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(3721..4284)
                     /locus_tag="LP245_003083"
     CDS             complement(3721..4284)
                     /locus_tag="LP245_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL1520908.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT         1625 a          716 c          801 g         1520 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacca ttgaagatgt aaggcagagc
       61 gatattgcgg tcattatctg cgtgcgctgc ggcaagatag cctgataata agactgatcg
      121 catagagggg tggtatttca caccgcccat tgtcaacagg cagttcagcc tcgttaaatt
      181 cagcatgggt atcacttatg aaaattcatc tacattggtg ataatagtaa atccagtagg
      241 gcgaaataat tgactgtaat ttacggggca aaacggcaca atctcaaacg agattgtgcc
      301 gtttaagggg aagattctag aaatatttca tacttccaac tatatagtta aggaggagac
      361 tgaaaatgaa gaagttgttt tttttattgt tattgttatt cttaatatac ttaggttatg
      421 actacgttaa tgaagcactg ttttctcagg aaaaagtcga atttcaaaat tatgatcaaa
      481 atcccaaaga acatttagaa aatagtggga cttctgaaaa tacccaagag aaaacaatta
      541 cagaagaaca ggtttatcaa ggaaatctgc tattaatcaa tagtaaatat cctgttcgcc
      601 aagaaagtgt gaagtcagat atcgtgaatt tatctaaaca tgacgaatta ataaatggat
      661 acgggttgct tgatagtaat atttatatgt caaaagaaat agcacaaaaa ttttcagaga
      721 tggtcaatga tgctgtaaag ggtggcgtta gtcattttat tattaatagt ggctatcgag
      781 actttgatga gcaaagtgtg ctttaccaag aaatgggggc tgagtatgcc ttaccagcag
      841 gttatagtga gcataattca ggtttatcac tagatgtagg atcaagcttg acgaaaatgg
      901 aacgagcccc tgaaggaaag tggatagaag aaaatgcttg gaaatacggg ttcattttac
      961 gttatccaga ggacaaaaca gagttaacag gaattcaata tgaaccatgg catattcgct
     1021 atgttggttt accacatagt gcgattatga aagaaaagaa tttcgttctc gaggaatata
     1081 tggattacct aaaagaagaa aaaaccattt ctgttagtgt aaatggggaa aaatatgaga
     1141 tcttttatta tcctgttact aaaaatacca ccattcatgt gccgactaat cttcgttatg
     1201 agatatcagg aaacaatata gacggtgtaa ttgtgacagt gtttcccgga tcaacacata
     1261 ctaattcaag gaggtaagga tggcggaatg aaaccaacga aattaatgaa cagcattatt
     1321 gtactagcac ttttggggta acgttagctt tttaatttaa aacccacgtt aactaggaca
     1381 ttgctatact aatgatacaa cttaaacaaa agaattagag gaaattatat tgggaaaaat
     1441 attatctaga ggattgctag ctttatattt agtgacacta atctggttag tgttattcaa
     1501 attacaatac aatattttat cagtatttaa ttatcatcaa agaagtctta acttgactcc
     1561 atttactgct actgggaatt tcagagagat gatagataat gttataatct ttattccatt
     1621 tggcttgctt ttgaatgtca attttaaaga aatcggattt ttacctaagt ttgcttttgt
     1681 actggtttta agtcttactt ttgaaataat tcaatttatc ttcgctattg gagcgacaga
     1741 cataacagat gtaattacaa atactgttgg aggctttctt ggactgaaat tatatggttt
     1801 aagcaataag catatgaatc aaaaaaaatt agacagagtt attatttttg taggtatact
     1861 tttgctcgta ttattgctcg tttaccgtac ccatttaaga ataaattacg tgtaagatgt
     1921 ctaaatcaag caatctgatc tttcatacac ataaagatat tgaatgaatt ggattagatg
     1981 gaaaacggga tgtggggaaa ctcgcccgta ggtgtgaagt gaggggaaaa ccggtgataa
     2041 agtaaaaagc ttacctaaca ctatagtaac aaagaaagcc caattatcaa ttttagtgct
     2101 gaggaattgg tctctttaat aaatttcctt aacgttgtaa atccgcattt tcctgacggt
     2161 acccccaaac taagatttca tagatagatt ttctgataac tttaaaaaac acgaatagcg
     2221 gaaaggatgt cttcattcgc taaagagtaa taaactactt ttccatcttg acgtgatttt
     2281 gccattccat gtttttttaa aaaacgtaaa tggtgtgacg ttgtagcgac actagcagta
     2341 agtatttctg ctaaatcaca gacgcacatt tccttatagg tttctaaagc atagaaaatt
     2401 ttaattctag aaaaatcgct gaaacatttc cctaacacaa gtaagtttga aaaatctttt
     2461 tgatccaatt tattttttat tccatttact ttttctttat gtacgacagt cacttggcaa
     2521 acttttttca ttcatctcac ctcacattca aacgattatt tgaatgaagt atacctattt
     2581 gatcactctt ttgtcaatct accttaattc caatacacta ttataagcaa tttcatgtat
     2641 tgaagtaaac ttacttgcaa gtgcgttttt gattccaagt taaaaacata ttattattct
     2701 acataatttc ctaatcaaat aaaactcctt tgaaaattgt tctaaaggag ttttattatt
     2761 ttgtatttct actaaaaata gcgtacaatg taattactaa gtaattacga aatgtaaaat
     2821 aatggaggaa ataatatgat tacaaaaaca agaaaacaag gaaattctat tatgttaacg
     2881 gtccctaaag aattcgatgt gcccaatggt gttgaagtag aagctaagct tgtagagaat
     2941 ggtatccttt atgagtttgt agagcctaaa aaagaatttt ttgattttag tgaagatatt
     3001 ttggctgata ttctttcaga aggttatagc aaacaagaga tcttaaaaga atttagaaat
     3061 agaaaaaatg cgttaacttc tgcatttaaa tctattgctg aagatactgt tgcaaattct
     3121 aaaccgatga caaaagagga gttggcagca gaaattggct tatgagattc taccttctaa
     3181 acacgtaata aagtatctaa aaaaattaaa agagaaaaca ttaaaagaac aatttttaac
     3241 gataatttat gatgagatag cagttcgtcc tcattcggga gaacaaaaaa cgggtgattt
     3301 atcaggaatt tgggctattg gattcaagta tgcaggtacg acatatcgcg ttgcatatga
     3361 aattaaagat aatgcagtga tacctatctt actatgtgga acgcatgaaa atttttatga
     3421 acaattaaaa aagattaggt aagaacccaa tgtttcaact tgagaggata gacgacactt
     3481 taaaagataa tttttaacag ctgagagttg taatacccta taattttaaa ccactaacct
     3541 atatatttat gaaaaataga aaaaattaaa acgcatttta agcctctttc aaattaaaag
     3601 cttcatcctt atgcacaaag agggcttaaa atgcgttatt ttatattgtt ttttagtaat
     3661 aataaaaaaa tcactctaat tctcccataa atattataga ttcctaaaga ttaaaataga
     3721 ttattcccta ttgtctttta agtagcggta gagtgttgcc ttgctaatac cagtcatttc
     3781 cgtaatttct tttacgctat aaacctgact tttatacaat tttactgctc gatcaacatc
     3841 tttctggttc actcgtggac ggccaccttt acgacctctc gcacgtgcac ttttcaaacc
     3901 ttctttggta cgttcaacaa ttaaatcacg ttcgaactga ctaaatgctt ggaagacagt
     3961 catcattaag cgtccgtgag gcgtgctggt atcgaagttt tctttcaagc tcaccagctt
     4021 aacatggtgt tcttcaaaat aggtaacaag gtcaatcaaa tcctttgtac tacgacccaa
     4081 tcgagaaaaa ctttctacaa ttaccgtatc tcccggacga attttatctt ttaaacgatt
     4141 tagttgggga cgaaccgctt tggttcccgt cattttctca gttaggattt cattacaatt
     4201 ttgttcattg agtaagtcta attgacgatt tagttcttgt gaacgtgtac tcactcgggc
     4261 ataaccataa atgtatccac tcatgctttt cttcctttcg tactttaatt ctggcttgat
     4321 tgtatcataa aagggagtta tagatacata gttaatgcaa caagttatga tacaaaatat
     4381 gacctctttt atttaataaa agaggtcatt tcattttgtc tcataatcga ttgtttttga
     4441 tacgagtgtg tatacgaaat aaacaaaaaa atcttaagta aatttctaga tacctaattt
     4501 aatcctaact agtgtatcct aaagttaata acgagtttat cacaatgaaa attataaaat
     4561 gctcccatat tagatataac atgcaatatt tgaattagaa ctacaaaatt tattcgtttt
     4621 ataaacgccg attgtaaaat taagctagac aactaaaaaa ag
//
LOCUS       DAFEEZ010000201         3000 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.guided.144, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000201
VERSION     DAFEEZ010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.guided.144"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            245..1213
                     /locus_tag="LP245_003084"
     CDS             245..1213
                     /locus_tag="LP245_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBL1520909.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1206..2237
                     /gene="vanA"
                     /locus_tag="LP245_003085"
     CDS             1206..2237
                     /gene="vanA"
                     /locus_tag="LP245_003085"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBL1520910.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2243..2851
                     /locus_tag="LP245_003086"
     CDS             2243..2851
                     /locus_tag="LP245_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBL1520911.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          894 a          574 c          722 g          810 t
ORIGIN      
        1 atgctggtgt catccaccaa catcaaaaag tatagagcca taatttttta ggaaaatctc
       61 aaggttatct ttactttttc ttaggaaatt aacaatttaa tattaagaaa cggctcgttc
      121 ttacacggta gacttaatac cgtaagaacg agccgttttc gttcttcaga gaaagatttg
      181 acaagattac cattggcatc cccgttttat ttggtgcctt tcacagaaag ggttggtctt
      241 aattatgaat aacatcggca ttactgttta tggatgtgag caggatgagg cagatgcatt
      301 ccatgctctt tcgcctcgct ttggcgttat ggcaacgata attaacgcca acgtgtcgga
      361 atccaacgcc aaatccgcgc ctttcaatca atgtatcagt gtgggacata aatcagagat
      421 ttccgcctct attcttcttg cgctgaagag agccggtgtg aaatatattt ctacccgaag
      481 catcggctgc aatcatatag atacaactgc tgctaagaga atgggcatca ctgtcgacaa
      541 tgtggcgtac tcgccggata gcgttgccga ttatactatg atgctaattc ttatggcagt
      601 acgcaacgta aaatcgattg tgcgctctgt ggaaaaacat gatttcaggt tggacagcga
      661 ccgtggcaag gtactcagcg acatgacagt tggtgtggtg ggaacgggcc agataggcaa
      721 agcggttatt gagcggctgc gaggatttgg atgtaaagtg ttggcttata gtcgcagccg
      781 aagtatagag gtaaactatg taccgtttga tgagttgctg caaaatagcg atatcgttac
      841 gcttcatgtg ccgctcaata cggatacgca ctatattatc agccacgaac aaatacagag
      901 aatgaagcaa ggagcatttc ttatcaatac tgggcgcggt ccacttgtag atacctatga
      961 gttggttaaa gcattagaaa acgggaaact gggcggtgcc gcattggatg tattggaagg
     1021 agaggaagag tttttctact ctgattgcac ccaaaaacca attgataatc aatttttact
     1081 taaacttcaa agaatgccta acgtgataat cacaccgcat acggcctatt ataccgagca
     1141 agcgttgcgt gataccgttg aaaaaaccat taaaaactgt ttggattttg aaaggagaca
     1201 ggagcatgaa tagaataaaa gttgcaatac tgtttggggg ttgctcagag gagcatgacg
     1261 tatcggtaaa atctgcaata gagatagccg ctaacattaa taaagaaaaa tacgagccgt
     1321 tatacattgg aattacgaaa tctggtgtat ggaaaatgtg cgaaaaacct tgcgcggaat
     1381 gggaaaacga caattgctat tcagctgtac tctcgccgga taaaaaaatg cacggattac
     1441 ttgttaaaaa gaaccatgaa tatgaaatca accatgttga tgtagcattt tcagctttgc
     1501 atggcaagtc aggtgaagat ggatccatac aaggtctgtt tgaattgtcc ggtatccctt
     1561 ttgtaggctg cgatattcaa agctcagcaa tttgtatgga caaatcgttg acatacatcg
     1621 ttgcgaaaaa tgctgggata gctactcccg ccttttgggt tattaataaa gatgataggc
     1681 cggtggcagc tacgtttacc tatcctgttt ttgttaagcc ggcgcgttca ggctcatcct
     1741 tcggtgtgaa aaaagtcaat agcgcggacg aattggacta cgcaattgaa tcggcaagac
     1801 aatatgacag caaaatctta attgagcagg ctgtttcggg ctgtgaggtc ggttgtgcgg
     1861 tattgggaaa cagtgccgcg ttagctgttg gcgaggtgga ccaaatcagg ctgcagtacg
     1921 gaatctttcg tattcatcag gaagtcgagc cggaaaaagg ctctgaaaac gcagttataa
     1981 ccgttcccgc agacctttca gcagaggagc gaggacggat acaggaaacg gcaaaaaaaa
     2041 tatataaagc gctcggctgt agaggtctag cccgtgtgga tatgttttta caagataacg
     2101 gccgcattgt actgaacgaa gtcaatactc tgcccggttt cacgtcatac agtcgttatc
     2161 cccgtatgat ggccgctgca ggtattgcac ttcccgaact gattgaccgc ttgatcgtat
     2221 tagcgttaaa ggggtgataa gcatggaaat aggatttact tttttagatg aaatagtaca
     2281 cggtgttcgt tgggacgcta aatatgccac ttgggataat ttcaccggaa aaccggttga
     2341 cggttatgaa gtaaatcgca ttgtagggac atacgagttg gctgaatcgc ttttgaaggc
     2401 aaaagaactg gctgctaccc aagggtacgg attgcttcta tgggacggtt accgtcctaa
     2461 tcgtgctgta aactgtttta tgcaatgggc tgcacagccg gaaaataacc tgacaaagga
     2521 aagttattat cccaatattg accgaactga gatgatttca aaaggatacg tggcttcaaa
     2581 atcaagccat agccgcggca gtgccattga tcttacgctt tatcgattag acacgggtga
     2641 gcttgtacca atggggagcc gatttgattt tatggatgaa cgctctcatc atgcggcaaa
     2701 tggaatatca tgcaatgaag cgcaaaatcg cagacgtttg cgctccatca tggaaaacag
     2761 tgggtttgaa gcatatagcc tcgaatggtg gcactatgta ttaagagacg aaccataccc
     2821 caatagctat tttgatttcc ccgttaaata aacttttaac cgttgcacgg acaaactata
     2881 taagctaact ctttcggcag gaaacccgac gtatgtaact ggttcttagg gaatttatat
     2941 atagtagata gtattgaaga ggttctgttg caaagtttta aataaagaat aaaatccctt
//
LOCUS       DAFEEZ010000202         1620 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR22780_1
            SAMN20574083-rid13343693.guided.164, whole genome shotgun sequence.
ACCESSION   DAFEEZ010000202
VERSION     DAFEEZ010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20574083
            Sequence Read Archive: SRR16917484
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001177207.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001177207.1
            Genome Coverage       :: 559x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 10:21:31
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,028
            Genes (coding)                    :: 2,960
            CDSs (with protein)               :: 2,960
            Genes (RNA)                       :: 60
            rRNAs                             :: 1, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 3, 2 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 31 of 68
            Pseudo Genes (incomplete)         :: 29 of 68
            Pseudo Genes (internal stop)      :: 16 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20574083-rid13343693.guided.164"
                     /isolate="PR22780_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2018-02"
                     /collected_by="University of Michigan"
     gene            <1..1348
                     /locus_tag="LP245_003087"
     CDS             <1..1348
                     /locus_tag="LP245_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HBL1520912.1"
                     /translation="DFILYLKLCNRTESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQI
                     YKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAV
                     ILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKY
                     LIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNT
                     NLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLR
                     QMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFE
                     GKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGE
                     DILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1478..>1620)
                     /locus_tag="LP245_003088"
     CDS             complement(1478..>1620)
                     /locus_tag="LP245_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL1520913.1"
                     /translation="QEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINF
                     DK"
BASE COUNT          664 a          143 c          273 g          540 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaaccgaa tcattaaaaa aacattatac
       61 agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg
      121 atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac
      181 tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg
      241 aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa
      301 tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc
      361 tggttttaga attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga
      421 ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata
      481 tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg
      541 ttatgatagt gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac
      601 taataagaaa aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt
      661 agaaactaat gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat
      721 actaggttat aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc
      781 agaagaagaa caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg
      841 tttagattat acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga
      901 gtatatattg ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat
      961 agaaagtttt atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg
     1021 ccataatgat tttagttgta atcatctatt gttagatggc aataatagat taactggaat
     1081 aattgatttt ggagattctg gaattataga tgaatattgt gattttatat acttacttga
     1141 agatagtgaa gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa
     1201 tatagatatt gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga
     1261 aactattgtt tatggaatta aaaatattaa acaggaattt atcgaaaatg gtagaaaaga
     1321 aatttataaa aggacttata aagattgatt atataatata tgaaaagcta ttataaaaga
     1381 cattagtatt aaatagttta aaaaaatgaa aaataataaa ggaagtgagt caagtccaga
     1441 ctcctgtgta aaatgctata caatgttttt accatttcta cttatcaaaa ttgatgtatt
     1501 ttcttgaaga ataaatccat tcatcatgta ggtccataag aacggctcca attaagcgat
     1561 tggctgatgt ttgattgggg aagatgcgaa taatcttttc tcttctgcgt acttcttgat
//
